locus-tag	class	description
C3363_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
C3363_RS00010	COG0592	DNA-directed DNA polymerase activity
C3363_RS00015	COG0762	integral membrane protein
C3363_RS00025	COG4137	Cytochrome C assembly protein
C3363_RS00030	COG4536	flavin adenine dinucleotide binding
C3363_RS00040	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C3363_RS00045	COG0716	FMN binding
C3363_RS00050	COG2826	transposase and inactivated derivatives, IS30 family
C3363_RS00065	COG1045	serine acetyltransferase
C3363_RS00075	COG0745	RESPONSE REGULATOR receiver
C3363_RS00080	COG0295	cytidine deaminase activity
C3363_RS00085	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C3363_RS00100	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
C3363_RS00105	COG0445	tRNA wobble uridine modification
C3363_RS00110	COG1349	DNA-binding transcription factor activity
C3363_RS00130	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
C3363_RS00135	COG1070	Carbohydrate kinase
C3363_RS00145	COG0235	Class ii aldolase
C3363_RS00160	COG3962	Belongs to the TPP enzyme family
C3363_RS00170	COG0673	inositol 2-dehydrogenase activity
C3363_RS00175	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C3363_RS00185	COG0673	inositol 2-dehydrogenase activity
C3363_RS00190	COG1172	Belongs to the binding-protein-dependent transport system permease family
C3363_RS00195	COG1129	ABC transporter
C3363_RS00200	COG1879	ABC-type sugar transport system periplasmic component
C3363_RS00210	COG3718	enzyme involved in inositol metabolism
C3363_RS00215	COG2168	tRNA wobble position uridine thiolation
C3363_RS00220	COG2923	Belongs to the DsrF TusC family
C3363_RS00225	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
C3363_RS00230	COG2964	Protein conserved in bacteria
C3363_RS00235	COG0545	Peptidyl-prolyl cis-trans isomerase
C3363_RS00240	COG2900	Belongs to the SlyX family
C3363_RS00245	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C3363_RS00265	COG4545	Glutaredoxin-related protein
C3363_RS00275	COG2852	Protein conserved in bacteria
C3363_RS00290	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C3363_RS00300	COG2830	Protein of unknown function (DUF452)
C3363_RS00305	COG2226	methyltransferase
C3363_RS00310	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
C3363_RS00325	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C3363_RS00340	COG5295	Hep Hag repeat protein
C3363_RS00370	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
C3363_RS00375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C3363_RS00380	COG4558	Periplasmic binding protein
C3363_RS00385	COG0758	DNA mediated transformation
C3363_RS00445	COG3728	DNA packaging
C3363_RS00480	COG0582	viral genome integration into host DNA
C3363_RS00495	COG3276	selenocysteine insertion sequence binding
C3363_RS00515	COG3171	Protein conserved in bacteria
C3363_RS00520	COG0220	tRNA (guanine-N7-)-methyltransferase activity
C3363_RS00525	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C3363_RS00530	COG0210	DNA helicase
C3363_RS00590	COG4974	Belongs to the 'phage' integrase family
C3363_RS00600	COG0494	nUDIX hydrolase
C3363_RS00605	COG3223	Belongs to the PsiE family
C3363_RS00630	COG1519	Transferase
C3363_RS00645	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
C3363_RS00650	COG0795	lipopolysaccharide-transporting ATPase activity
C3363_RS00655	COG0795	lipopolysaccharide-transporting ATPase activity
C3363_RS00670	COG3590	peptidase
C3363_RS00705	COG0202	RNA polymerase activity
C3363_RS00720	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C3363_RS00730	COG0201	protein transport
C3363_RS00745	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
C3363_RS00765	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C3363_RS00780	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
C3363_RS00820	COG1876	peptidase activity
C3363_RS00825	COG4172	Belongs to the ABC transporter superfamily
C3363_RS00840	COG0747	negative chemotaxis
C3363_RS00845	COG2005	Transcriptional regulator
C3363_RS00850	COG0725	ABC transporter, periplasmic molybdate-binding protein
C3363_RS00900	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C3363_RS00905	COG2195	Cleaves the N-terminal amino acid of tripeptides
C3363_RS00910	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
C3363_RS00915	COG0194	GDP metabolic process
C3363_RS00920	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
C3363_RS00930	COG2852	Protein conserved in bacteria
C3363_RS00935	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C3363_RS00940	COG1459	type II secretion system
C3363_RS00955	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
C3363_RS00965	COG2166	iron-sulfur cluster assembly
C3363_RS00975	COG0009	L-threonylcarbamoyladenylate synthase
C3363_RS00980	COG1187	pseudouridine synthase activity
C3363_RS00995	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C3363_RS01000	COG0512	Glutamine amidotransferase of anthranilate synthase
C3363_RS01010	COG0134	indole-3-glycerol-phosphate synthase activity
C3363_RS01010	COG0135	phosphoribosylanthranilate isomerase activity
C3363_RS01020	COG0159	tryptophan synthase activity
C3363_RS01025	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
C3363_RS01045	COG3177	Filamentation induced by cAMP protein fic
C3363_RS01055	COG0525	valine-tRNA ligase activity
C3363_RS01060	COG2990	Protein conserved in bacteria
C3363_RS01080	COG3700	Belongs to the class B bacterial acid phosphatase family
C3363_RS01090	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C3363_RS01095	COG3172	ATPase kinase involved in NAD metabolism
C3363_RS01100	COG2129	metallophosphoesterase
C3363_RS01105	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
C3363_RS01110	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C3363_RS01120	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C3363_RS01155	COG3085	chromosome segregation
C3363_RS01160	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
C3363_RS01165	COG1522	sequence-specific DNA binding
C3363_RS01220	COG3328	transposase activity
C3363_RS01255	COG0335	large ribosomal subunit rRNA binding
C3363_RS01270	COG0335	large ribosomal subunit rRNA binding
C3363_RS01275	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C3363_RS01285	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
C3363_RS01290	COG0291	Belongs to the bacterial ribosomal protein bL35 family
C3363_RS01315	COG2195	Cleaves the N-terminal amino acid of tripeptides
C3363_RS01325	COG0561	phosphatase activity
C3363_RS01335	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C3363_RS01340	COG0733	neurotransmitter:sodium symporter activity
C3363_RS01345	COG0686	Belongs to the AlaDH PNT family
C3363_RS01350	COG0569	domain protein
C3363_RS01355	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C3363_RS01380	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C3363_RS01395	COG4804	nuclease activity
C3363_RS01415	COG1739	Uncharacterized protein family UPF0029
C3363_RS01425	COG0594	ribonuclease P activity
C3363_RS01430	COG0230	Belongs to the bacterial ribosomal protein bL34 family
C3363_RS01455	COG0387	Pfam Sodium calcium exchanger
C3363_RS01480	COG0180	Tryptophanyl-tRNA synthetase
C3363_RS01490	COG3161	chorismate lyase activity
C3363_RS01525	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C3363_RS01540	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C3363_RS01545	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C3363_RS01550	COG1584	GPR1 FUN34 yaaH family protein
C3363_RS01565	COG3719	Belongs to the RNase T2 family
C3363_RS01570	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C3363_RS01575	COG0728	peptidoglycan biosynthetic process
C3363_RS01595	COG0497	DNA recombination
C3363_RS01620	COG0861	Integral membrane protein TerC family
C3363_RS01625	COG1380	Effector of murein hydrolase LrgA
C3363_RS01630	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
C3363_RS01635	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C3363_RS01645	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
C3363_RS01650	COG0848	biopolymer transport protein
C3363_RS01655	COG0811	peptide transport
C3363_RS01665	COG0616	signal peptide processing
C3363_RS01670	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C3363_RS01680	COG2226	methyltransferase
C3363_RS01700	COG0037	tRNA processing
C3363_RS01730	COG3468	outer membrane autotransporter barrel domain protein
C3363_RS01735	COG0488	(ABC) transporter
C3363_RS01740	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C3363_RS01750	COG0602	queuosine metabolic process
C3363_RS01755	COG0720	synthase
C3363_RS01780	COG0805	protein transport
C3363_RS01785	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C3363_RS01840	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C3363_RS01865	COG0456	acetyltransferase
C3363_RS01880	COG0513	Belongs to the DEAD box helicase family
C3363_RS01890	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
C3363_RS01895	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C3363_RS01940	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C3363_RS01945	COG2003	Belongs to the UPF0758 family
C3363_RS01970	COG0745	RESPONSE REGULATOR receiver
C3363_RS01975	COG0642	Histidine kinase
C3363_RS01995	COG1085	galactose-1-phosphate uridylyltransferase
C3363_RS02035	COG0697	spore germination
C3363_RS02040	COG0697	spore germination
C3363_RS02055	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C3363_RS02070	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C3363_RS02075	COG4145	pantothenate transmembrane transporter activity
C3363_RS02080	COG3924	membrane
C3363_RS02090	COG0598	Magnesium transport protein CorA
C3363_RS02095	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C3363_RS02105	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C3363_RS02110	COG2271	Major facilitator Superfamily
C3363_RS02115	COG0545	Peptidyl-prolyl cis-trans isomerase
C3363_RS02125	COG0204	Acyl-transferase
C3363_RS02150	COG1263	PTS System
C3363_RS02150	COG2190	(PTS) system
C3363_RS02150	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C3363_RS02170	COG0582	viral genome integration into host DNA
C3363_RS02180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C3363_RS02185	COG0765	amino acid transport
C3363_RS02190	COG1126	abc transporter atp-binding protein
C3363_RS02200	COG0493	'glutamate synthase
C3363_RS02205	COG0070	glutamate synthase
C3363_RS02205	COG0067	glutamate synthase
C3363_RS02205	COG0069	glutamate synthase activity
C3363_RS02240	COG0251	oxidation-reduction process
C3363_RS02245	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C3363_RS02250	COG0583	DNA-binding transcription factor activity
C3363_RS02255	COG1011	Hydrolase
C3363_RS02260	COG0583	DNA-binding transcription factor activity
C3363_RS02270	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C3363_RS02275	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C3363_RS02290	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
C3363_RS02295	COG1426	Protein conserved in bacteria
C3363_RS02300	COG0616	signal peptide processing
C3363_RS02310	COG3201	nicotinamide mononucleotide transporter
C3363_RS02315	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
C3363_RS02320	COG4133	protoheme IX ABC transporter activity
C3363_RS02325	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C3363_RS02330	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C3363_RS02335	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C3363_RS02340	COG0471	metal ion transport
C3363_RS02345	COG0126	phosphoglycerate kinase activity
C3363_RS02350	COG0191	fructose-bisphosphate aldolase activity
C3363_RS02355	COG4172	Belongs to the ABC transporter superfamily
C3363_RS02360	COG0778	Nitroreductase
C3363_RS02370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C3363_RS02395	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C3363_RS02395	COG0517	IMP dehydrogenase activity
C3363_RS02400	COG3063	Type IV pilus biogenesis stability protein PilW
C3363_RS02415	COG2944	sequence-specific DNA binding
C3363_RS02420	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
C3363_RS02465	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C3363_RS02490	COG0330	HflC and HflK could
C3363_RS02495	COG0330	HflC and HflK could
C3363_RS02500	COG0456	acetyltransferase
C3363_RS02505	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C3363_RS02525	COG1538	Outer membrane efflux protein
C3363_RS02530	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C3363_RS02535	COG0346	lactoylglutathione lyase activity
C3363_RS02545	COG2911	Protein conserved in bacteria
C3363_RS02575	COG0280	phosphate acetyltransferase
C3363_RS02575	COG0281	malic enzyme
C3363_RS02580	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
C3363_RS02585	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C3363_RS02605	COG0469	pyruvate kinase activity
C3363_RS02610	COG2062	phosphohistidine phosphatase, SixA
C3363_RS02640	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C3363_RS02650	COG0583	DNA-binding transcription factor activity
C3363_RS02665	COG0500	methyltransferase
C3363_RS02670	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
C3363_RS02685	COG0308	aminopeptidase N
C3363_RS02695	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
C3363_RS02700	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
C3363_RS02705	COG0802	atpase or kinase
C3363_RS02710	COG0860	N-Acetylmuramoyl-L-alanine amidase
C3363_RS02710	COG1388	LysM domain
C3363_RS02720	COG1434	Gram-negative-bacterium-type cell wall biogenesis
C3363_RS02725	COG1083	cytidylyl-transferase
C3363_RS02740	COG1216	Glycosyl transferase, family 2
C3363_RS02745	COG1138	Cytochrome C-type biogenesis protein
C3363_RS02755	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
C3363_RS02760	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
C3363_RS02765	COG1077	Cell shape determining protein MreB Mrl
C3363_RS02770	COG1792	Involved in formation and maintenance of cell shape
C3363_RS02775	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
C3363_RS02790	COG3392	D12 class N6 adenine-specific DNA methyltransferase
C3363_RS02885	COG4397	Mu-like prophage major head subunit gpT
C3363_RS02895	COG5005	Phage virion morphogenesis
C3363_RS02905	COG2369	cell adhesion
C3363_RS02910	COG4383	Mu-like prophage protein gp29
C3363_RS02950	COG3023	N-Acetylmuramoyl-L-alanine amidase
C3363_RS02980	COG4396	Host-nuclease inhibitor protein Gam
C3363_RS02995	COG2842	Transposition protein
C3363_RS03010	COG3423	Transcriptional regulator
C3363_RS03015	COG2932	Transcriptional regulator
C3363_RS03050	COG1629	transport
C3363_RS03050	COG4771	TonB-dependent receptor
C3363_RS03055	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C3363_RS03065	COG1560	Kdo2-lipid A biosynthetic process
C3363_RS03070	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
C3363_RS03075	COG0393	Putative heavy-metal-binding
C3363_RS03080	COG2983	Belongs to the UPF0260 family
C3363_RS03085	COG0556	nucleotide-excision repair
C3363_RS03095	COG4171	peptide transport system, permease
C3363_RS03100	COG4172	Belongs to the ABC transporter superfamily
C3363_RS03115	COG0187	DNA topoisomerase II activity
C3363_RS03120	COG0753	catalase activity
C3363_RS03125	COG1408	metallophosphoesterase
C3363_RS03130	COG3120	sequence-specific DNA binding
C3363_RS03135	COG1067	ATP-dependent peptidase activity
C3363_RS03170	COG0534	Mate efflux family protein
C3363_RS03175	COG0564	pseudouridine synthase activity
C3363_RS03180	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
C3363_RS03190	COG3639	organic phosphonate transmembrane transporter activity
C3363_RS03210	COG0730	response to heat
C3363_RS03225	COG0716	FMN binding
C3363_RS03230	COG0735	belongs to the Fur family
C3363_RS03235	COG3008	intermembrane lipid transfer
C3363_RS03245	COG3676	manually curated
C3363_RS03250	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
C3363_RS03255	COG0793	Belongs to the peptidase S41A family
C3363_RS03260	COG2989	Protein conserved in bacteria
C3363_RS03265	COG3108	Peptidase M15
C3363_RS03270	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C3363_RS03275	COG2853	Lipoprotein
C3363_RS03280	COG2932	Transcriptional regulator
C3363_RS03285	COG0626	cystathionine gamma-synthase activity
C3363_RS03295	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C3363_RS03300	COG0538	isocitrate dehydrogenase activity
C3363_RS03310	COG0372	Belongs to the citrate synthase family
C3363_RS03315	COG0563	adenylate kinase activity
C3363_RS03320	COG0733	neurotransmitter:sodium symporter activity
C3363_RS03325	COG0338	D12 class N6 adenine-specific DNA methyltransferase
C3363_RS03330	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
C3363_RS03335	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C3363_RS03340	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
C3363_RS03365	COG4796	Type ii and iii secretion system protein
C3363_RS03375	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
C3363_RS03380	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C3363_RS03385	COG1280	lysine exporter protein (LysE YggA)
C3363_RS03390	COG3118	belongs to the thioredoxin family
C3363_RS03400	COG2050	protein possibly involved in aromatic compounds catabolism
C3363_RS03405	COG0247	lactate metabolic process
C3363_RS03405	COG0277	FAD linked oxidase domain protein
C3363_RS03410	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
C3363_RS03410	COG2885	chlorophyll binding
C3363_RS03420	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C3363_RS03425	COG4974	Belongs to the 'phage' integrase family
C3363_RS03430	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C3363_RS03480	COG1053	succinate dehydrogenase
C3363_RS03485	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C3363_RS03495	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
C3363_RS03525	COG1965	Belongs to the frataxin family
C3363_RS03535	COG2259	Doxx family
C3363_RS03545	COG3220	belongs to the UPF0276 family
C3363_RS03550	COG3219	Protein conserved in bacteria
C3363_RS03555	COG1595	DNA-templated transcription, initiation
C3363_RS03570	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C3363_RS03575	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C3363_RS03580	COG1131	(ABC) transporter
C3363_RS03585	COG0842	Transport permease protein
C3363_RS03600	COG2925	Exonuclease
C3363_RS03605	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
C3363_RS03610	COG0613	PHP domain protein
C3363_RS03615	COG0440	acetolactate synthase activity
C3363_RS03620	COG0028	Belongs to the TPP enzyme family
C3363_RS03630	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C3363_RS03635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C3363_RS03650	COG0626	cystathionine gamma-synthase activity
C3363_RS03655	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C3363_RS03670	COG3691	Protein conserved in bacteria
C3363_RS03680	COG1083	cytidylyl-transferase
C3363_RS03685	COG2244	polysaccharide biosynthetic process
C3363_RS03700	COG0438	transferase activity, transferring glycosyl groups
C3363_RS03705	COG3306	glycosyltransferase involved in LPS biosynthesis
C3363_RS03715	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C3363_RS03720	COG1596	polysaccharide export
C3363_RS03735	COG1959	2 iron, 2 sulfur cluster binding
C3363_RS03745	COG0822	iron-sulfur transferase activity
C3363_RS03770	COG0633	Ferredoxin
C3363_RS03775	COG2975	iron-sulfur cluster assembly
C3363_RS03780	COG1132	(ABC) transporter
C3363_RS03795	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C3363_RS03805	COG1271	oxidase subunit
C3363_RS03810	COG1294	oxidase, subunit
C3363_RS03825	COG0824	Thioesterase
C3363_RS03830	COG0811	peptide transport
C3363_RS03835	COG0848	biopolymer transport protein
C3363_RS03840	COG3064	Membrane
C3363_RS03845	COG0823	Involved in the tonB-independent uptake of proteins
C3363_RS03855	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
C3363_RS03860	COG3647	Membrane
C3363_RS03865	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C3363_RS03880	COG1530	ribonuclease E activity
C3363_RS03885	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C3363_RS03895	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
C3363_RS03900	COG1137	ATPase activity
C3363_RS03905	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C3363_RS03915	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C3363_RS03935	COG0747	negative chemotaxis
C3363_RS03940	COG1760	l-serine dehydratase
C3363_RS03940	COG1760	l-serine dehydratase
C3363_RS03950	COG1120	ATPase activity
C3363_RS03955	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C3363_RS03970	COG0058	SHG alpha-glucan phosphorylase activity
C3363_RS03980	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C3363_RS03985	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
C3363_RS03995	COG1477	protein flavinylation
C3363_RS04000	COG2991	Protein conserved in bacteria
C3363_RS04045	COG3116	cell division
C3363_RS04050	COG0768	penicillin binding
C3363_RS04055	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C3363_RS04060	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C3363_RS04070	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C3363_RS04075	COG0772	Belongs to the SEDS family
C3363_RS04105	COG0849	cell division
C3363_RS04125	COG0481	GTPase activity
C3363_RS04130	COG0681	Belongs to the peptidase S26 family
C3363_RS04150	COG1943	Transposase
C3363_RS04155	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C3363_RS04165	COG0528	UMP kinase activity
C3363_RS04180	COG1944	ATP diphosphatase activity
C3363_RS04185	COG2252	PERMEase
C3363_RS04190	COG0628	permease
C3363_RS04195	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C3363_RS04210	COG3978	acetolactate synthase activity
C3363_RS04250	COG0494	nUDIX hydrolase
C3363_RS04255	COG1238	metal cluster binding
C3363_RS04260	COG2116	formate transmembrane transporter activity
C3363_RS04265	COG1882	Formate acetyltransferase
C3363_RS04270	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C3363_RS04275	COG2268	Band 7 protein
C3363_RS04285	COG0786	glutamate:sodium symporter activity
C3363_RS04290	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
C3363_RS04295	COG3105	Protein conserved in bacteria
C3363_RS04315	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C3363_RS04320	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
C3363_RS04325	COG1840	ABC-type Fe3 transport system, periplasmic component
C3363_RS04340	COG0305	Participates in initiation and elongation during chromosome replication
C3363_RS04355	COG1509	lysine 2,3-aminomutase activity
C3363_RS04375	COG3074	FtsZ-dependent cytokinesis
C3363_RS04380	COG1435	thymidine kinase activity
C3363_RS04385	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C3363_RS04390	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C3363_RS04390	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C3363_RS04395	COG0670	Belongs to the BI1 family
C3363_RS04400	COG0542	response to heat
C3363_RS04405	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C3363_RS04410	COG0739	heme binding
C3363_RS04415	COG1121	(ABC) transporter
C3363_RS04420	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C3363_RS04425	COG0121	glutamine amidotransferase
C3363_RS04430	COG3684	Belongs to the aldolase LacD family
C3363_RS04445	COG3716	PTS system mannose fructose sorbose family IID component
C3363_RS04455	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C3363_RS04460	COG2222	sugar isomerase
C3363_RS04465	COG1349	DNA-binding transcription factor activity
C3363_RS04495	COG0195	Participates in both transcription termination and antitermination
C3363_RS04500	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
C3363_RS04525	COG0583	DNA-binding transcription factor activity
C3363_RS04530	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C3363_RS04535	COG3083	sulfuric ester hydrolase activity
C3363_RS04545	COG3642	lipopolysaccharide core region biosynthetic process
C3363_RS04550	COG0302	gtp cyclohydrolase
C3363_RS04555	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C3363_RS04555	COG0301	tRNA thio-modification
C3363_RS04565	COG3026	antisigma factor binding
C3363_RS04575	COG0318	PFAM AMP-dependent synthetase and ligase
C3363_RS04580	COG4942	peptidase
C3363_RS04585	COG2861	carbohydrate metabolic process
C3363_RS04590	COG0729	surface antigen
C3363_RS04595	COG2911	Protein conserved in bacteria
C3363_RS04605	COG4988	ABC transporter
C3363_RS04610	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C3363_RS04615	COG0494	nUDIX hydrolase
C3363_RS04640	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C3363_RS04645	COG0617	tRNA 3'-terminal CCA addition
C3363_RS04650	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C3363_RS04655	COG1640	4-alpha-glucanotransferase
C3363_RS04660	COG3833	ABC-type maltose transport systems, permease component
C3363_RS04680	COG3842	ATPase activity
C3363_RS04685	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C3363_RS04705	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C3363_RS04710	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C3363_RS04715	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C3363_RS04725	COG1960	acyl-CoA dehydrogenase activity
C3363_RS04735	COG0189	ligase activity
C3363_RS04745	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
C3363_RS04765	COG0617	tRNA 3'-terminal CCA addition
C3363_RS04770	COG0778	Nitroreductase
C3363_RS04775	COG3691	Protein conserved in bacteria
C3363_RS04790	COG3021	interspecies interaction between organisms
C3363_RS04805	COG1494	fructose-1,6-bisphosphatase
C3363_RS04810	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C3363_RS04820	COG0561	phosphatase activity
C3363_RS04830	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C3363_RS04835	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C3363_RS04870	COG0437	4 iron, 4 sulfur cluster binding
C3363_RS04875	COG2864	formate dehydrogenase
C3363_RS04890	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
C3363_RS04895	COG1523	belongs to the glycosyl hydrolase 13 family
C3363_RS04900	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C3363_RS04910	COG0517	IMP dehydrogenase activity
C3363_RS04910	COG0516	GMP reductase activity
C3363_RS04915	COG3955	Domain of unknown function (DUF1919)
C3363_RS04975	COG4735	regulation of single-species biofilm formation
C3363_RS05000	COG0708	Exodeoxyribonuclease III
C3363_RS05005	COG2056	Na+-H+ antiporter family
C3363_RS05010	COG0037	tRNA processing
C3363_RS05035	COG1522	sequence-specific DNA binding
C3363_RS05040	COG1674	ftsk spoiiie
C3363_RS05045	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C3363_RS05050	COG1214	PFAM Peptidase M22, glycoprotease
C3363_RS05065	COG3021	interspecies interaction between organisms
C3363_RS05080	COG0187	DNA topoisomerase II activity
C3363_RS05085	COG3945	hemerythrin HHE cation binding domain
C3363_RS05090	COG0425	Belongs to the sulfur carrier protein TusA family
C3363_RS05105	COG0312	modulator of DNA gyrase
C3363_RS05125	COG2814	Major facilitator Superfamily
C3363_RS05135	COG2205	protein histidine kinase activity
C3363_RS05140	COG0745	RESPONSE REGULATOR receiver
C3363_RS05145	COG3956	TIGRFAM MazG family protein
C3363_RS05150	COG0006	proline dipeptidase activity
C3363_RS05170	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
C3363_RS05175	COG0732	type I restriction modification DNA specificity domain
C3363_RS05180	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
C3363_RS05195	COG0564	pseudouridine synthase activity
C3363_RS05210	COG0248	Ppx GppA phosphatase
C3363_RS05215	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
C3363_RS05220	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
C3363_RS05225	COG1278	Cold shock
C3363_RS05230	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C3363_RS05235	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C3363_RS05240	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
C3363_RS05245	COG0741	lytic transglycosylase activity
C3363_RS05250	COG2826	transposase and inactivated derivatives, IS30 family
C3363_RS05300	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C3363_RS05305	COG0629	single-stranded DNA binding
C3363_RS05310	COG1373	ATPase (AAA superfamily
C3363_RS05320	COG0513	Belongs to the DEAD box helicase family
C3363_RS05325	COG3093	addiction module antidote protein HigA
C3363_RS05350	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C3363_RS05360	COG0596	Alpha beta hydrolase
C3363_RS05370	COG0318	PFAM AMP-dependent synthetase and ligase
C3363_RS05375	COG3264	Mechanosensitive ion channel
C3363_RS05375	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
C3363_RS05395	COG1940	carbohydrate kinase activity
C3363_RS05395	COG1846	Transcriptional regulator
C3363_RS05400	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
C3363_RS05425	COG1943	Transposase
C3363_RS05485	COG3328	transposase activity
C3363_RS05515	COG0857	belongs to the CobB CobQ family
C3363_RS05515	COG0280	phosphate acetyltransferase
C3363_RS05525	COG2969	positive regulation of protein catabolic process
C3363_RS05530	COG0625	glutathione transferase activity
C3363_RS05540	COG0285	dihydrofolate synthase activity
C3363_RS05560	COG1448	Aminotransferase
C3363_RS05565	COG0697	spore germination
C3363_RS05570	COG2081	HI0933 family
C3363_RS05580	COG1737	Transcriptional regulator
C3363_RS05585	COG2731	YhcH YjgK YiaL family protein
C3363_RS05660	COG2369	cell adhesion
C3363_RS05680	COG0582	viral genome integration into host DNA
C3363_RS05690	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C3363_RS05700	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
C3363_RS05710	COG2363	Small membrane protein
C3363_RS05745	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
C3363_RS05750	COG0314	molybdopterin synthase activity
C3363_RS05760	COG1444	tRNA N-acetyltransferase activity
C3363_RS05765	COG1879	ABC-type sugar transport system periplasmic component
C3363_RS05770	COG1129	ABC transporter
C3363_RS05775	COG4211	Belongs to the binding-protein-dependent transport system permease family
C3363_RS05795	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C3363_RS05800	COG2095	MarC family integral membrane protein
C3363_RS05805	COG4166	transmembrane transport
C3363_RS05810	COG0489	protein tyrosine kinase activity
C3363_RS05815	COG5295	Hep Hag repeat protein
C3363_RS05815	COG5295	Hep Hag repeat protein
C3363_RS05830	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C3363_RS05835	COG0023	Translation Initiation Factor
C3363_RS05845	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
C3363_RS05850	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
C3363_RS05860	COG0539	negative regulation of cytoplasmic translation
C3363_RS05865	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
C3363_RS05870	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C3363_RS05880	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C3363_RS05890	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C3363_RS05895	COG0589	response to stress
C3363_RS05905	COG2333	competence protein COMEC
C3363_RS05905	COG0658	competence protein
C3363_RS05910	COG2350	Protein conserved in bacteria
C3363_RS05915	COG1607	acyl-coa hydrolase
C3363_RS05930	COG3092	negative regulation of chromosome organization
C3363_RS05935	COG0590	tRNA wobble adenosine to inosine editing
C3363_RS05940	COG0513	Belongs to the DEAD box helicase family
C3363_RS05945	COG4785	May be involved in cell division
C3363_RS05955	COG4178	(ABC) transporter
C3363_RS05970	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C3363_RS05975	COG2198	Histidine kinase
C3363_RS05975	COG5002	protein histidine kinase activity
C3363_RS05975	COG0784	Response regulator, receiver
C3363_RS05985	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C3363_RS06000	COG2949	membrane
C3363_RS06005	COG0697	spore germination
C3363_RS06010	COG0437	4 iron, 4 sulfur cluster binding
C3363_RS06020	COG2183	response to ionizing radiation
C3363_RS06025	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C3363_RS06030	COG0508	dehydrogenase complex catalyzes the overall conversion of
C3363_RS06035	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
C3363_RS06040	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C3363_RS06050	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C3363_RS06055	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C3363_RS06075	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C3363_RS06075	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
C3363_RS06095	COG0303	'Molybdopterin
C3363_RS06105	COG2095	MarC family integral membrane protein
C3363_RS06120	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C3363_RS06130	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C3363_RS06150	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
C3363_RS06170	COG0586	Pfam SNARE associated Golgi protein
C3363_RS06185	COG2840	Smr protein MutS2
C3363_RS06190	COG0814	amino acid
C3363_RS06195	COG0814	amino acid
C3363_RS06205	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C3363_RS06210	COG0785	Cytochrome C biogenesis protein
C3363_RS06215	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C3363_RS06215	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C3363_RS06225	COG1595	DNA-templated transcription, initiation
C3363_RS06340	COG0305	Participates in initiation and elongation during chromosome replication
C3363_RS06390	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C3363_RS06400	COG3422	double-strand break repair
C3363_RS06445	COG2951	lytic endotransglycosylase activity
C3363_RS06450	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
C3363_RS06480	COG0058	SHG alpha-glucan phosphorylase activity
C3363_RS06490	COG0567	Dehydrogenase, E1 component
C3363_RS06495	COG0508	dehydrogenase complex catalyzes the overall conversion of
C3363_RS06505	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C3363_RS06510	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C3363_RS06510	COG0475	glutathione-regulated potassium exporter activity
C3363_RS06520	COG2852	Protein conserved in bacteria
C3363_RS06530	COG3106	COG3106 Predicted ATPase
C3363_RS06535	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C3363_RS06540	COG0709	Synthesizes selenophosphate from selenide and ATP
C3363_RS06545	COG3036	rescue of stalled ribosome
C3363_RS06550	COG2226	methyltransferase
C3363_RS06570	COG1368	sulfuric ester hydrolase activity
C3363_RS06575	COG0633	Ferredoxin
C3363_RS06575	COG3217	Mosc domain protein beta barrel domain protein
C3363_RS06585	COG0142	geranyltranstransferase activity
C3363_RS06600	COG0183	Belongs to the thiolase family
C3363_RS06605	COG1556	Lactate utilization protein
C3363_RS06610	COG1139	Iron-sulfur cluster binding protein
C3363_RS06615	COG0247	lactate metabolic process
C3363_RS06620	COG1620	l-lactate permease
C3363_RS06625	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C3363_RS06630	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C3363_RS06635	COG0730	response to heat
C3363_RS06640	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C3363_RS06665	COG0783	Belongs to the Dps family
C3363_RS06680	COG0792	nuclease activity
C3363_RS06685	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
C3363_RS06690	COG2823	Periplasmic or secreted lipoprotein
C3363_RS06695	COG1127	ABC transporter
C3363_RS06700	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C3363_RS06705	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C3363_RS06710	COG2854	intermembrane phospholipid transfer
C3363_RS06720	COG5007	Belongs to the BolA IbaG family
C3363_RS06730	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C3363_RS06735	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C3363_RS06740	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
C3363_RS06740	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
C3363_RS06755	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C3363_RS06785	COG0815	Transfers the fatty acyl group on membrane lipoproteins
C3363_RS06810	COG1595	DNA-templated transcription, initiation
C3363_RS06815	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
C3363_RS06820	COG3025	triphosphatase activity
C3363_RS06845	COG2867	negative regulation of translational initiation
C3363_RS06850	COG2914	Belongs to the UPF0125 (RnfH) family
C3363_RS06865	COG0564	pseudouridine synthase activity
C3363_RS06870	COG3098	single-species biofilm formation
C3363_RS06885	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C3363_RS06905	COG0251	oxidation-reduction process
C3363_RS06915	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C3363_RS06920	COG1286	toxin biosynthetic process
C3363_RS06925	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C3363_RS06940	COG0791	NLP P60 protein
C3363_RS06960	COG1392	Phosphate transport regulator
C3363_RS06965	COG0306	phosphate transporter
C3363_RS06970	COG4991	sh3 domain protein
C3363_RS07010	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C3363_RS07015	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C3363_RS07020	COG2032	superoxide dismutase activity
C3363_RS07025	COG4591	ABC-type transport system involved in lipoprotein release permease component
C3363_RS07030	COG2364	Membrane
C3363_RS07060	COG0012	GTP binding
C3363_RS07165	COG3728	DNA packaging
C3363_RS07215	COG1349	DNA-binding transcription factor activity
C3363_RS07245	COG3068	Protein conserved in bacteria
C3363_RS07250	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
C3363_RS07255	COG0676	glucose-6-phosphate 1-epimerase activity
C3363_RS07265	COG3842	ATPase activity
C3363_RS07270	COG1176	ABC-type spermidine putrescine transport system, permease component I
C3363_RS07275	COG1177	transmembrane transport
C3363_RS07285	COG2976	Protein conserved in bacteria
C3363_RS07290	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C3363_RS07295	COG2814	Major facilitator Superfamily
C3363_RS07310	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
C3363_RS07315	COG4149	molybdate abc transporter
C3363_RS07320	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C3363_RS07340	COG2431	L-lysine efflux transmembrane transporter activity
C3363_RS07345	COG3023	N-Acetylmuramoyl-L-alanine amidase
C3363_RS07350	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
C3363_RS07365	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C3363_RS07385	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C3363_RS07390	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C3363_RS07405	COG1943	Transposase
C3363_RS07410	COG3759	membrane
C3363_RS07420	COG0363	glucosamine-6-phosphate deaminase activity
C3363_RS07425	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C3363_RS07430	COG1218	3'(2'),5'-bisphosphate nucleotidase
C3363_RS07470	COG3306	glycosyltransferase involved in LPS biosynthesis
C3363_RS07480	COG0859	PFAM glycosyl transferase family 9
C3363_RS07485	COG0583	DNA-binding transcription factor activity
C3363_RS07495	COG1199	ATP-dependent helicase activity
C3363_RS07510	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C3363_RS07520	COG1025	Belongs to the peptidase M16 family
C3363_RS07530	COG1115	amino acid carrier protein
C3363_RS07535	COG0181	hydroxymethylbilane synthase activity
C3363_RS07545	COG2959	enzyme of heme biosynthesis
C3363_RS07550	COG3071	HemY protein
C3363_RS07560	COG2909	trisaccharide binding
C3363_RS07570	COG4172	Belongs to the ABC transporter superfamily
C3363_RS07575	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C3363_RS07580	COG0601	transmembrane transport
C3363_RS07585	COG4166	transmembrane transport
C3363_RS07590	COG2255	four-way junction helicase activity
C3363_RS07595	COG0475	glutathione-regulated potassium exporter activity
C3363_RS07595	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C3363_RS07640	COG1534	Rna-binding protein
C3363_RS07645	COG0463	Glycosyl transferase, family 2
C3363_RS07650	COG0492	ferredoxin-NADP+ reductase activity
C3363_RS07655	COG3118	belongs to the thioredoxin family
C3363_RS07670	COG1090	epimerase
C3363_RS07685	COG0859	PFAM glycosyl transferase family 9
C3363_RS07695	COG0778	Nitroreductase
C3363_RS07700	COG3101	peptidyl-lysine hydroxylation
C3363_RS07720	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
C3363_RS07725	COG1862	Preprotein translocase
C3363_RS07730	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C3363_RS07735	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C3363_RS07765	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C3363_RS07775	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C3363_RS07780	COG2190	(PTS) system
C3363_RS07785	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C3363_RS07815	COG0495	leucyl-tRNA aminoacylation
C3363_RS07820	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
C3363_RS07825	COG1466	dna polymerase III delta subunit
C3363_RS07830	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
C3363_RS07835	COG0237	dephospho-CoA kinase activity
C3363_RS07840	COG1393	Belongs to the ArsC family
C3363_RS07845	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C3363_RS07855	COG0494	nUDIX hydrolase
C3363_RS07875	COG4608	Belongs to the ABC transporter superfamily
C3363_RS07880	COG0444	Belongs to the ABC transporter superfamily
C3363_RS07885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C3363_RS07890	COG0601	transmembrane transport
C3363_RS07895	COG0747	negative chemotaxis
C3363_RS07900	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C3363_RS07915	COG1678	Uncharacterized ACR, COG1678
C3363_RS07920	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C3363_RS07925	COG3056	Lipoprotein
C3363_RS07930	COG0271	Belongs to the BolA IbaG family
C3363_RS07940	COG0564	pseudouridine synthase activity
C3363_RS07945	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C3363_RS07970	COG0196	riboflavin kinase activity
C3363_RS07990	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C3363_RS07995	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
C3363_RS08065	COG3077	Addiction module antitoxin, RelB DinJ family
C3363_RS08105	COG0740	serine-type endopeptidase activity
C3363_RS08135	COG3772	lysozyme
C3363_RS08205	COG1028	Short-chain dehydrogenase reductase Sdr
C3363_RS08210	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C3363_RS08215	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C3363_RS08220	COG0142	geranyltranstransferase activity
C3363_RS08225	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C3363_RS08230	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C3363_RS08235	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C3363_RS08240	COG0859	PFAM glycosyl transferase family 9
C3363_RS08250	COG3061	Opacity-associated protein A
C3363_RS08250	COG3266	domain, Protein
C3363_RS08255	COG1555	photosystem II stabilization
C3363_RS08265	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
C3363_RS08270	COG0084	hydrolase, TatD family'
C3363_RS08280	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C3363_RS08285	COG1215	transferase activity, transferring glycosyl groups
C3363_RS08290	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C3363_RS08305	COG2814	Major facilitator Superfamily
C3363_RS08320	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
C3363_RS08335	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C3363_RS08365	COG1720	tRNA m6t6A37 methyltransferase activity
C3363_RS08370	COG1575	Belongs to the MenA family. Type 1 subfamily
C3363_RS08380	COG1663	tetraacyldisaccharide 4'-kinase activity
C3363_RS08390	COG3721	Heme iron utilization protein
C3363_RS08395	COG0748	coenzyme F420 binding
C3363_RS08400	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
C3363_RS08425	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C3363_RS08430	COG4160	amino acid transport
C3363_RS08435	COG4215	(ABC) transporter
C3363_RS08440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C3363_RS08445	COG1126	abc transporter atp-binding protein
C3363_RS08450	COG0210	DNA helicase
C3363_RS08465	COG2965	DNA replication, synthesis of RNA primer
C3363_RS08475	COG0477	Major facilitator Superfamily
C3363_RS08490	COG0537	adenosine 5'-monophosphoramidase activity
C3363_RS08505	COG0316	Belongs to the HesB IscA family
C3363_RS08505	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
C3363_RS08515	COG1805	sodium ion transport
C3363_RS08520	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
C3363_RS08525	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
C3363_RS08535	COG2871	sodium ion transport
C3363_RS08540	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
C3363_RS08545	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
C3363_RS08550	COG1178	ABC-type Fe3 transport system permease component
C3363_RS08560	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
C3363_RS08565	COG0437	4 iron, 4 sulfur cluster binding
C3363_RS08570	COG3301	Polysulphide reductase, NrfD
C3363_RS08580	COG0560	Phosphoserine phosphatase
C3363_RS08595	COG1162	GTPase activity
C3363_RS08605	COG1121	(ABC) transporter
C3363_RS08610	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C3363_RS08615	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C3363_RS08620	COG4316	Uncharacterized protein conserved in bacteria (DUF2251)
C3363_RS08635	COG1396	sequence-specific DNA binding
C3363_RS08640	COG1621	beta-fructofuranosidase activity
C3363_RS08650	COG2824	Alkylphosphonate utilization operon protein PhnA
C3363_RS08655	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C3363_RS08660	COG1027	Aspartate ammonia-lyase
C3363_RS08675	COG2027	D-alanyl-D-alanine carboxypeptidase
C3363_RS08680	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C3363_RS08685	COG3328	transposase activity
C3363_RS08700	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C3363_RS08705	COG4608	Belongs to the ABC transporter superfamily
C3363_RS08710	COG0444	Belongs to the ABC transporter superfamily
C3363_RS08730	COG0788	formyltetrahydrofolate deformylase activity
C3363_RS08735	COG2916	Histone family protein nucleoid-structuring protein H-NS
C3363_RS08740	COG1757	Na H antiporter
C3363_RS08745	COG1138	Cytochrome C-type biogenesis protein
C3363_RS08755	COG4235	cytochrome complex assembly
C3363_RS08755	COG3088	subunit of a heme lyase
C3363_RS08760	COG4235	cytochrome complex assembly
C3363_RS08760	COG3088	subunit of a heme lyase
C3363_RS08765	COG3842	ATPase activity
C3363_RS08775	COG1840	ABC-type Fe3 transport system, periplasmic component
C3363_RS08780	COG1858	cytochrome C peroxidase
C3363_RS08785	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
C3363_RS08795	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C3363_RS08820	COG1122	ATPase activity
C3363_RS08855	COG0582	viral genome integration into host DNA
C3363_RS08930	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C3363_RS08940	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
C3363_RS08960	COG0512	Glutamine amidotransferase of anthranilate synthase
C3363_RS08965	COG1322	Protein conserved in bacteria
C3363_RS08975	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C3363_RS08980	COG0641	radical SAM
C3363_RS08995	COG2960	long-chain fatty acid transporting porin activity
C3363_RS09025	COG0009	L-threonylcarbamoyladenylate synthase
C3363_RS09030	COG0551	DNA topoisomerase type I activity
C3363_RS09040	COG2137	regulation of response to DNA damage stimulus
C3363_RS09050	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C3363_RS09070	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C3363_RS09080	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C3363_RS09105	COG1530	ribonuclease E activity
C3363_RS09110	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C3363_RS09120	COG0747	negative chemotaxis
C3363_RS09135	COG4166	transmembrane transport
C3363_RS09140	COG4168	peptide transport system, permease
C3363_RS09150	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C3363_RS09175	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C3363_RS09180	COG0546	phosphoglycolate phosphatase activity
C3363_RS09200	COG1522	sequence-specific DNA binding
C3363_RS09200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C3363_RS09210	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C3363_RS09235	COG3102	Protein conserved in bacteria
C3363_RS09240	COG0018	arginyl-trna synthetase
C3363_RS09250	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C3363_RS09290	COG0321	lipoyl(octanoyl) transferase activity
C3363_RS09295	COG2921	Belongs to the UPF0250 family
C3363_RS09300	COG1686	Belongs to the peptidase S11 family
C3363_RS09310	COG0772	Belongs to the SEDS family
C3363_RS09315	COG0768	penicillin binding
C3363_RS09320	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
C3363_RS09325	COG0799	negative regulation of ribosome biogenesis
C3363_RS09345	COG1263	PTS System
C3363_RS09345	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C3363_RS09375	COG1702	phosphate starvation-inducible protein PhoH
C3363_RS09380	COG4143	(ABC) transporter
C3363_RS09385	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C3363_RS09400	COG0436	Aminotransferase
C3363_RS09405	COG1169	isochorismate synthase
C3363_RS09410	COG0671	phosphoesterase, PA-phosphatase related
C3363_RS09415	COG1940	carbohydrate kinase activity
C3363_RS09430	COG0575	Belongs to the CDS family
C3363_RS09435	COG0750	zinc metalloprotease
C3363_RS09450	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C3363_RS09455	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C3363_RS09465	COG0460	homoserine dehydrogenase
C3363_RS09465	COG0527	aspartate kinase activity
C3363_RS09470	COG0083	homoserine kinase activity
C3363_RS09475	COG0287	Prephenate dehydrogenase
C3363_RS09475	COG1605	Chorismate mutase
C3363_RS09480	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C3363_RS09485	COG0859	PFAM glycosyl transferase family 9
C3363_RS09490	COG2920	part of a sulfur-relay system
C3363_RS09500	COG1115	amino acid carrier protein
C3363_RS09505	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
C3363_RS09510	COG3683	transport system, periplasmic component
C3363_RS09520	COG0339	signal peptide processing
C3363_RS09525	COG0077	Prephenate dehydratase
C3363_RS09525	COG1605	Chorismate mutase
C3363_RS09540	COG0439	Biotin carboxylase
C3363_RS09545	COG0511	ligase activity, forming carbon-carbon bonds
C3363_RS09565	COG1399	metal-binding, possibly nucleic acid-binding protein
C3363_RS09575	COG0416	fatty acid biosynthetic process
C3363_RS09580	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C3363_RS09585	COG0076	glutamate decarboxylase activity
C3363_RS09590	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C3363_RS09600	COG1561	YicC-like family, N-terminal region
C3363_RS09605	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C3363_RS09610	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
C3363_RS09610	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
C3363_RS09615	COG2832	Protein of unknown function (DUF454)
C3363_RS09620	COG0521	Mo-molybdopterin cofactor biosynthetic process
C3363_RS09630	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
C3363_RS09640	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
C3363_RS09645	COG1194	a g-specific adenine glycosylase
C3363_RS09670	COG0247	lactate metabolic process
C3363_RS09680	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C3363_RS09695	COG0564	pseudouridine synthase activity
C3363_RS09700	COG0668	transmembrane transport
C3363_RS09705	COG0501	Belongs to the peptidase M48B family
C3363_RS09710	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
C3363_RS09715	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C3363_RS09820	COG2610	gluconate transmembrane transporter activity
C3363_RS09825	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C3363_RS09830	COG3622	Belongs to the hyi family
C3363_RS09835	COG0235	Class ii aldolase
C3363_RS09840	COG3395	kinase activity
C3363_RS09845	COG2084	Dehydrogenase
C3363_RS09850	COG1349	DNA-binding transcription factor activity
C3363_RS09860	COG0625	glutathione transferase activity
C3363_RS09880	COG2177	Part of the ABC transporter FtsEX involved in
C3363_RS09885	COG2884	Cell division ATP-binding protein ftsE
C3363_RS09890	COG0552	protein localization to endoplasmic reticulum
C3363_RS09895	COG0742	ribosomal rna small subunit methyltransferase
C3363_RS09930	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C3363_RS09935	COG3550	peptidyl-serine autophosphorylation
C3363_RS09965	COG0351	phosphomethylpyrimidine kinase
C3363_RS09970	COG0352	thiamine-phosphate diphosphorylase activity
C3363_RS09980	COG4804	nuclease activity
C3363_RS10000	COG0300	oxidoreductase activity
C3363_RS10005	COG2207	Transcriptional regulator
C3363_RS10020	COG0789	Transcriptional regulator
C3363_RS10070	COG3550	peptidyl-serine autophosphorylation
C3363_RS10090	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C3363_RS10120	COG1414	Transcriptional regulator
C3363_RS10130	COG3084	Protein conserved in bacteria
C3363_RS10135	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C3363_RS10140	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C3363_RS10145	COG1309	transcriptional regulator
C3363_RS10150	COG0583	DNA-binding transcription factor activity
C3363_RS10155	COG0730	response to heat
C3363_RS10160	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C3363_RS10170	COG3119	arylsulfatase activity
C3363_RS10175	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C3363_RS10185	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C3363_RS10190	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C3363_RS10195	COG3062	negative regulation of establishment of protein localization
C3363_RS10205	COG0437	4 iron, 4 sulfur cluster binding
C3363_RS10210	COG0348	domain, Protein
C3363_RS10215	COG3043	anaerobic respiration
C3363_RS10220	COG3005	denitrification pathway
C3363_RS10225	COG1609	Transcriptional regulator
C3363_RS10230	COG3265	gluconokinase activity
C3363_RS10235	COG2610	gluconate transmembrane transporter activity
C3363_RS10240	COG1694	Mazg nucleotide pyrophosphohydrolase
C3363_RS10260	COG0235	Class ii aldolase
C3363_RS10265	COG3623	hexulose-6-phosphate isomerase
C3363_RS10280	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
C3363_RS10285	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
C3363_RS10315	COG0300	oxidoreductase activity
C3363_RS10320	COG4232	protein-disulfide reductase activity
C3363_RS10325	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
C3363_RS10330	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C3363_RS10380	COG0354	folic acid binding
C3363_RS10390	COG2995	paraquat-inducible protein a
C3363_RS10415	COG4942	peptidase
C3363_RS10415	COG1388	LysM domain
C3363_RS10420	COG1388	LysM domain
C3363_RS10420	COG4942	peptidase
C3363_RS10425	COG1238	metal cluster binding
C3363_RS10430	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
C3363_RS10460	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C3363_RS10480	COG0470	DNA polymerase III
C3363_RS10485	COG0606	chelatase, subunit chli
C3363_RS10505	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C3363_RS10510	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
C3363_RS10520	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C3363_RS10520	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C3363_RS10525	COG3715	PTS system
C3363_RS10530	COG3716	PTS system mannose fructose sorbose family IID component
C3363_RS10540	COG1482	cell wall glycoprotein biosynthetic process
C3363_RS10545	COG1129	ABC transporter
C3363_RS10550	COG1172	Belongs to the binding-protein-dependent transport system permease family
C3363_RS10555	COG1879	ABC-type sugar transport system periplasmic component
C3363_RS10575	COG1733	regulation of RNA biosynthetic process
C3363_RS10590	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
C3363_RS10635	COG2259	Doxx family
C3363_RS10655	COG0791	NLP P60 protein
C3363_RS10665	COG3381	protein complex oligomerization
C3363_RS10705	COG1022	Amp-dependent synthetase and ligase
C3363_RS10710	COG2927	DNA polymerase III (CHI subunit)
C3363_RS10730	COG2017	converts alpha-aldose to the beta-anomer
C3363_RS10740	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C3363_RS10780	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
C3363_RS10795	COG2878	Part of a membrane complex involved in electron transport
C3363_RS10800	COG4656	Part of a membrane complex involved in electron transport
C3363_RS10825	COG1560	Kdo2-lipid A biosynthetic process
C3363_RS10830	COG2226	methyltransferase
C3363_RS10835	COG1252	NADH dehydrogenase
C3363_RS10840	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C3363_RS10845	COG0402	S-adenosylhomocysteine deaminase activity
C3363_RS10850	COG4591	ABC-type transport system involved in lipoprotein release permease component
C3363_RS10860	COG0288	reversible hydration of carbon dioxide
C3363_RS10865	COG4221	oxidoreductase activity
C3363_RS10875	COG0754	glutathionylspermidine amidase activity
C3363_RS10880	COG2252	PERMEase
C3363_RS10895	COG0330	HflC and HflK could
C3363_RS10900	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C3363_RS10905	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C3363_RS10910	COG1643	Atp-dependent helicase
C3363_RS10945	COG1074	ATP-dependent DNA helicase activity
C3363_RS10975	COG1028	Short-chain dehydrogenase reductase Sdr
C3363_RS10990	COG0174	glutamine synthetase
C3363_RS10995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C3363_RS11000	COG1879	ABC-type sugar transport system periplasmic component
C3363_RS11005	COG1172	Belongs to the binding-protein-dependent transport system permease family
C3363_RS11020	COG1609	Transcriptional regulator
C3363_RS11025	COG0355	proton-transporting ATP synthase activity, rotational mechanism
C3363_RS11050	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
C3363_RS11070	COG0490	domain, Protein
C3363_RS11070	COG0471	metal ion transport
C3363_RS11105	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
C3363_RS11115	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
C3363_RS11125	COG0089	rRNA binding
C3363_RS11140	COG0051	transcription antitermination factor activity, RNA binding
C3363_RS11155	COG0439	Biotin carboxylase
C3363_RS11170	COG0019	diaminopimelate decarboxylase activity
C3363_RS11175	COG0814	amino acid
C3363_RS11190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C3363_RS11195	COG1966	Carbon starvation protein
C3363_RS11220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C3363_RS11245	COG0024	Methionine aminopeptidase
C3363_RS11250	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C3363_RS11255	COG1349	DNA-binding transcription factor activity
C3363_RS11290	COG3111	PFAM Bacterial OB fold (BOF) protein
C3363_RS11295	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C3363_RS11300	COG2850	peptidyl-arginine hydroxylation
C3363_RS11305	COG4285	Biotin-protein ligase, N terminal
C3363_RS11310	COG1268	BioY protein
C3363_RS11315	COG0561	phosphatase activity
C3363_RS11320	COG1040	competence protein
C3363_RS11325	COG0084	hydrolase, TatD family'
C3363_RS11330	COG0557	exoribonuclease II activity
C3363_RS11335	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane