locus-tag	class	description
FLK62_RS00010	COG0592	DNA-directed DNA polymerase activity
FLK62_RS00015	COG0762	integral membrane protein
FLK62_RS00025	COG4137	Cytochrome C assembly protein
FLK62_RS00030	COG4536	flavin adenine dinucleotide binding
FLK62_RS00040	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FLK62_RS00045	COG0716	FMN binding
FLK62_RS00055	COG1045	serine acetyltransferase
FLK62_RS00065	COG0745	RESPONSE REGULATOR receiver
FLK62_RS00070	COG0295	cytidine deaminase activity
FLK62_RS00075	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FLK62_RS00090	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FLK62_RS00115	COG0445	tRNA wobble uridine modification
FLK62_RS00120	COG1349	DNA-binding transcription factor activity
FLK62_RS00140	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
FLK62_RS00145	COG1070	Carbohydrate kinase
FLK62_RS00155	COG0235	Class ii aldolase
FLK62_RS00170	COG3962	Belongs to the TPP enzyme family
FLK62_RS00180	COG0673	inositol 2-dehydrogenase activity
FLK62_RS00185	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FLK62_RS00195	COG0673	inositol 2-dehydrogenase activity
FLK62_RS00200	COG1172	Belongs to the binding-protein-dependent transport system permease family
FLK62_RS00205	COG1129	ABC transporter
FLK62_RS00210	COG1879	ABC-type sugar transport system periplasmic component
FLK62_RS00220	COG3718	enzyme involved in inositol metabolism
FLK62_RS00225	COG1129	ABC transporter
FLK62_RS00235	COG2168	tRNA wobble position uridine thiolation
FLK62_RS00240	COG2923	Belongs to the DsrF TusC family
FLK62_RS00245	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FLK62_RS00250	COG2964	Protein conserved in bacteria
FLK62_RS00255	COG0545	Peptidyl-prolyl cis-trans isomerase
FLK62_RS00260	COG2900	Belongs to the SlyX family
FLK62_RS00265	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FLK62_RS00285	COG4545	Glutaredoxin-related protein
FLK62_RS00295	COG2852	Protein conserved in bacteria
FLK62_RS00310	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FLK62_RS00320	COG2830	Protein of unknown function (DUF452)
FLK62_RS00325	COG2226	methyltransferase
FLK62_RS00330	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FLK62_RS00345	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FLK62_RS00350	COG4206	TonB-dependent receptor
FLK62_RS00350	COG1629	transport
FLK62_RS00360	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FLK62_RS00365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FLK62_RS00370	COG4558	Periplasmic binding protein
FLK62_RS00375	COG0758	DNA mediated transformation
FLK62_RS00415	COG3276	selenocysteine insertion sequence binding
FLK62_RS00445	COG3171	Protein conserved in bacteria
FLK62_RS00450	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FLK62_RS00455	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FLK62_RS00460	COG0210	DNA helicase
FLK62_RS00510	COG4974	Belongs to the 'phage' integrase family
FLK62_RS00520	COG0494	nUDIX hydrolase
FLK62_RS00550	COG1519	Transferase
FLK62_RS00565	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FLK62_RS00570	COG0795	lipopolysaccharide-transporting ATPase activity
FLK62_RS00575	COG0795	lipopolysaccharide-transporting ATPase activity
FLK62_RS00590	COG3590	peptidase
FLK62_RS00600	COG3676	manually curated
FLK62_RS00615	COG3328	transposase activity
FLK62_RS00655	COG3328	transposase activity
FLK62_RS00675	COG0202	RNA polymerase activity
FLK62_RS00690	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FLK62_RS00700	COG0201	protein transport
FLK62_RS00715	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FLK62_RS00735	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FLK62_RS00770	COG3328	transposase activity
FLK62_RS00785	COG1876	peptidase activity
FLK62_RS00790	COG4172	Belongs to the ABC transporter superfamily
FLK62_RS00805	COG0747	negative chemotaxis
FLK62_RS00810	COG2005	Transcriptional regulator
FLK62_RS00815	COG0725	ABC transporter, periplasmic molybdate-binding protein
FLK62_RS00865	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FLK62_RS00870	COG2195	Cleaves the N-terminal amino acid of tripeptides
FLK62_RS00875	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FLK62_RS00885	COG0194	GDP metabolic process
FLK62_RS00890	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FLK62_RS00900	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FLK62_RS00905	COG1459	type II secretion system
FLK62_RS00920	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FLK62_RS00930	COG2166	iron-sulfur cluster assembly
FLK62_RS00935	COG0471	metal ion transport
FLK62_RS00940	COG0009	L-threonylcarbamoyladenylate synthase
FLK62_RS00945	COG1187	pseudouridine synthase activity
FLK62_RS00960	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FLK62_RS00965	COG0512	Glutamine amidotransferase of anthranilate synthase
FLK62_RS00975	COG0134	indole-3-glycerol-phosphate synthase activity
FLK62_RS00975	COG0135	phosphoribosylanthranilate isomerase activity
FLK62_RS00985	COG0159	tryptophan synthase activity
FLK62_RS00990	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FLK62_RS01005	COG2153	protein acetylation
FLK62_RS01025	COG0525	valine-tRNA ligase activity
FLK62_RS01030	COG2990	Protein conserved in bacteria
FLK62_RS01050	COG3700	Belongs to the class B bacterial acid phosphatase family
FLK62_RS01060	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FLK62_RS01065	COG3172	ATPase kinase involved in NAD metabolism
FLK62_RS01070	COG2129	metallophosphoesterase
FLK62_RS01075	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FLK62_RS01080	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FLK62_RS01090	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FLK62_RS01125	COG3085	chromosome segregation
FLK62_RS01130	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
FLK62_RS01135	COG1522	sequence-specific DNA binding
FLK62_RS01155	COG3328	transposase activity
FLK62_RS01195	COG0640	Transcriptional regulator
FLK62_RS01335	COG3392	D12 class N6 adenine-specific DNA methyltransferase
FLK62_RS01375	COG0335	large ribosomal subunit rRNA binding
FLK62_RS01390	COG0335	large ribosomal subunit rRNA binding
FLK62_RS01395	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FLK62_RS01405	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FLK62_RS01410	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FLK62_RS01425	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FLK62_RS01440	COG2195	Cleaves the N-terminal amino acid of tripeptides
FLK62_RS01450	COG0561	phosphatase activity
FLK62_RS01460	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FLK62_RS01465	COG0733	neurotransmitter:sodium symporter activity
FLK62_RS01470	COG0686	Belongs to the AlaDH PNT family
FLK62_RS01475	COG0569	domain protein
FLK62_RS01480	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FLK62_RS01500	COG4804	nuclease activity
FLK62_RS01510	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FLK62_RS01555	COG2358	TRAP transporter, solute receptor (TAXI family
FLK62_RS01560	COG1739	Uncharacterized protein family UPF0029
FLK62_RS01570	COG0594	ribonuclease P activity
FLK62_RS01575	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FLK62_RS01600	COG0387	Pfam Sodium calcium exchanger
FLK62_RS01630	COG0180	Tryptophanyl-tRNA synthetase
FLK62_RS01640	COG3161	chorismate lyase activity
FLK62_RS01675	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FLK62_RS01690	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FLK62_RS01695	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FLK62_RS01700	COG1584	GPR1 FUN34 yaaH family protein
FLK62_RS01715	COG3719	Belongs to the RNase T2 family
FLK62_RS01720	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FLK62_RS01725	COG0728	peptidoglycan biosynthetic process
FLK62_RS01745	COG0497	DNA recombination
FLK62_RS01765	COG0861	Integral membrane protein TerC family
FLK62_RS01775	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FLK62_RS01780	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FLK62_RS01790	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FLK62_RS01795	COG0848	biopolymer transport protein
FLK62_RS01800	COG0811	peptide transport
FLK62_RS01810	COG0616	signal peptide processing
FLK62_RS01815	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FLK62_RS01825	COG2226	methyltransferase
FLK62_RS01845	COG0037	tRNA processing
FLK62_RS01860	COG3328	transposase activity
FLK62_RS01865	COG3468	outer membrane autotransporter barrel domain protein
FLK62_RS01880	COG3468	outer membrane autotransporter barrel domain protein
FLK62_RS01885	COG0488	(ABC) transporter
FLK62_RS01890	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FLK62_RS01900	COG0602	queuosine metabolic process
FLK62_RS01905	COG0720	synthase
FLK62_RS01930	COG0805	protein transport
FLK62_RS01935	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FLK62_RS01995	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FLK62_RS02020	COG0456	acetyltransferase
FLK62_RS02035	COG0513	Belongs to the DEAD box helicase family
FLK62_RS02045	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FLK62_RS02050	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FLK62_RS02095	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FLK62_RS02100	COG2003	Belongs to the UPF0758 family
FLK62_RS02125	COG0745	RESPONSE REGULATOR receiver
FLK62_RS02130	COG0642	Histidine kinase
FLK62_RS02150	COG1085	galactose-1-phosphate uridylyltransferase
FLK62_RS02180	COG0697	spore germination
FLK62_RS02185	COG0697	spore germination
FLK62_RS02200	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FLK62_RS02215	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FLK62_RS02220	COG4145	pantothenate transmembrane transporter activity
FLK62_RS02225	COG3924	membrane
FLK62_RS02235	COG0598	Magnesium transport protein CorA
FLK62_RS02240	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FLK62_RS02250	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FLK62_RS02260	COG0545	Peptidyl-prolyl cis-trans isomerase
FLK62_RS02270	COG0204	Acyl-transferase
FLK62_RS02295	COG1263	PTS System
FLK62_RS02295	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FLK62_RS02295	COG2190	(PTS) system
FLK62_RS02310	COG0582	viral genome integration into host DNA
FLK62_RS02320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FLK62_RS02325	COG0765	amino acid transport
FLK62_RS02330	COG1126	abc transporter atp-binding protein
FLK62_RS02340	COG0493	'glutamate synthase
FLK62_RS02345	COG0067	glutamate synthase
FLK62_RS02345	COG0070	glutamate synthase
FLK62_RS02345	COG0069	glutamate synthase activity
FLK62_RS02385	COG0251	oxidation-reduction process
FLK62_RS02390	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FLK62_RS02395	COG0583	DNA-binding transcription factor activity
FLK62_RS02400	COG1011	Hydrolase
FLK62_RS02405	COG0583	DNA-binding transcription factor activity
FLK62_RS02415	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FLK62_RS02420	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FLK62_RS02425	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FLK62_RS02430	COG1426	Protein conserved in bacteria
FLK62_RS02435	COG0616	signal peptide processing
FLK62_RS02445	COG3201	nicotinamide mononucleotide transporter
FLK62_RS02450	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FLK62_RS02455	COG4133	protoheme IX ABC transporter activity
FLK62_RS02460	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FLK62_RS02465	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FLK62_RS02470	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FLK62_RS02475	COG0471	metal ion transport
FLK62_RS02480	COG0126	phosphoglycerate kinase activity
FLK62_RS02485	COG0191	fructose-bisphosphate aldolase activity
FLK62_RS02490	COG4172	Belongs to the ABC transporter superfamily
FLK62_RS02495	COG0778	Nitroreductase
FLK62_RS02505	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FLK62_RS02530	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FLK62_RS02530	COG0517	IMP dehydrogenase activity
FLK62_RS02535	COG3063	Type IV pilus biogenesis stability protein PilW
FLK62_RS02595	COG2608	mercury ion transmembrane transporter activity
FLK62_RS02605	COG1674	ftsk spoiiie
FLK62_RS02625	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FLK62_RS02650	COG0330	HflC and HflK could
FLK62_RS02655	COG0330	HflC and HflK could
FLK62_RS02660	COG0456	acetyltransferase
FLK62_RS02665	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FLK62_RS02685	COG1538	Outer membrane efflux protein
FLK62_RS02690	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FLK62_RS02695	COG0346	lactoylglutathione lyase activity
FLK62_RS02705	COG2911	Protein conserved in bacteria
FLK62_RS02730	COG1476	TRANSCRIPTIONal
FLK62_RS02740	COG0280	phosphate acetyltransferase
FLK62_RS02740	COG0281	malic enzyme
FLK62_RS02745	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FLK62_RS02750	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FLK62_RS02770	COG0469	pyruvate kinase activity
FLK62_RS02775	COG2062	phosphohistidine phosphatase, SixA
FLK62_RS02790	COG3328	transposase activity
FLK62_RS02795	COG2932	Transcriptional regulator
FLK62_RS02800	COG2853	Lipoprotein
FLK62_RS02805	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FLK62_RS02810	COG3108	Peptidase M15
FLK62_RS02815	COG2989	Protein conserved in bacteria
FLK62_RS02820	COG0793	Belongs to the peptidase S41A family
FLK62_RS02825	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
FLK62_RS02840	COG3008	intermembrane lipid transfer
FLK62_RS02845	COG0735	belongs to the Fur family
FLK62_RS02850	COG0716	FMN binding
FLK62_RS02865	COG0730	response to heat
FLK62_RS02880	COG3639	organic phosphonate transmembrane transporter activity
FLK62_RS02885	COG3639	organic phosphonate transmembrane transporter activity
FLK62_RS02895	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
FLK62_RS02905	COG2337	Toxic component of a toxin-antitoxin (TA) module
FLK62_RS02910	COG0564	pseudouridine synthase activity
FLK62_RS02915	COG0534	Mate efflux family protein
FLK62_RS02950	COG1067	ATP-dependent peptidase activity
FLK62_RS02955	COG3120	sequence-specific DNA binding
FLK62_RS02960	COG1408	metallophosphoesterase
FLK62_RS02965	COG0753	catalase activity
FLK62_RS02970	COG0187	DNA topoisomerase II activity
FLK62_RS02985	COG4172	Belongs to the ABC transporter superfamily
FLK62_RS02990	COG4171	peptide transport system, permease
FLK62_RS03000	COG0556	nucleotide-excision repair
FLK62_RS03005	COG2983	Belongs to the UPF0260 family
FLK62_RS03010	COG0393	Putative heavy-metal-binding
FLK62_RS03015	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FLK62_RS03020	COG1560	Kdo2-lipid A biosynthetic process
FLK62_RS03030	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FLK62_RS03040	COG1629	transport
FLK62_RS03040	COG4771	TonB-dependent receptor
FLK62_RS03070	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FLK62_RS03075	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FLK62_RS03080	COG1792	Involved in formation and maintenance of cell shape
FLK62_RS03085	COG1077	Cell shape determining protein MreB Mrl
FLK62_RS03090	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FLK62_RS03095	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FLK62_RS03105	COG1138	Cytochrome C-type biogenesis protein
FLK62_RS03110	COG1216	Glycosyl transferase, family 2
FLK62_RS03115	COG1216	Glycosyl transferase, family 2
FLK62_RS03125	COG1083	cytidylyl-transferase
FLK62_RS03130	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FLK62_RS03140	COG1388	LysM domain
FLK62_RS03140	COG0860	N-Acetylmuramoyl-L-alanine amidase
FLK62_RS03145	COG0802	atpase or kinase
FLK62_RS03150	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FLK62_RS03155	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FLK62_RS03165	COG0308	aminopeptidase N
FLK62_RS03180	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
FLK62_RS03185	COG0500	methyltransferase
FLK62_RS03200	COG0583	DNA-binding transcription factor activity
FLK62_RS03210	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FLK62_RS03220	COG2271	Major facilitator Superfamily
FLK62_RS03230	COG3328	transposase activity
FLK62_RS03235	COG0626	cystathionine gamma-synthase activity
FLK62_RS03245	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FLK62_RS03250	COG0538	isocitrate dehydrogenase activity
FLK62_RS03260	COG0372	Belongs to the citrate synthase family
FLK62_RS03265	COG0563	adenylate kinase activity
FLK62_RS03270	COG0733	neurotransmitter:sodium symporter activity
FLK62_RS03275	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FLK62_RS03280	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FLK62_RS03285	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FLK62_RS03290	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FLK62_RS03315	COG4796	Type ii and iii secretion system protein
FLK62_RS03325	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FLK62_RS03330	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FLK62_RS03335	COG1280	lysine exporter protein (LysE YggA)
FLK62_RS03340	COG3118	belongs to the thioredoxin family
FLK62_RS03350	COG2050	protein possibly involved in aromatic compounds catabolism
FLK62_RS03355	COG0247	lactate metabolic process
FLK62_RS03355	COG0277	FAD linked oxidase domain protein
FLK62_RS03360	COG2885	chlorophyll binding
FLK62_RS03360	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FLK62_RS03370	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FLK62_RS03375	COG4974	Belongs to the 'phage' integrase family
FLK62_RS03380	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FLK62_RS03400	COG2801	Transposase and inactivated derivatives
FLK62_RS03410	COG2842	Transposition protein
FLK62_RS03465	COG3023	N-Acetylmuramoyl-L-alanine amidase
FLK62_RS03510	COG4383	Mu-like prophage protein gp29
FLK62_RS03515	COG2369	cell adhesion
FLK62_RS03520	COG5005	Phage virion morphogenesis
FLK62_RS03530	COG4397	Mu-like prophage major head subunit gpT
FLK62_RS03625	COG3392	D12 class N6 adenine-specific DNA methyltransferase
FLK62_RS03640	COG1053	succinate dehydrogenase
FLK62_RS03645	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FLK62_RS03655	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FLK62_RS03685	COG1965	Belongs to the frataxin family
FLK62_RS03715	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FLK62_RS03720	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FLK62_RS03725	COG1131	(ABC) transporter
FLK62_RS03730	COG0842	Transport permease protein
FLK62_RS03745	COG2925	Exonuclease
FLK62_RS03750	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
FLK62_RS03760	COG0613	PHP domain protein
FLK62_RS03765	COG0440	acetolactate synthase activity
FLK62_RS03770	COG0028	Belongs to the TPP enzyme family
FLK62_RS03780	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FLK62_RS03785	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FLK62_RS03790	COG1309	transcriptional regulator
FLK62_RS03800	COG0626	cystathionine gamma-synthase activity
FLK62_RS03805	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FLK62_RS03815	COG3691	Protein conserved in bacteria
FLK62_RS03825	COG1083	cytidylyl-transferase
FLK62_RS03830	COG1045	serine acetyltransferase
FLK62_RS03835	COG2244	polysaccharide biosynthetic process
FLK62_RS03850	COG0438	transferase activity, transferring glycosyl groups
FLK62_RS03855	COG3306	glycosyltransferase involved in LPS biosynthesis
FLK62_RS03865	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FLK62_RS03870	COG1596	polysaccharide export
FLK62_RS03880	COG0489	protein tyrosine kinase activity
FLK62_RS03880	COG3206	protein involved in exopolysaccharide biosynthesis
FLK62_RS03885	COG1959	2 iron, 2 sulfur cluster binding
FLK62_RS03895	COG0822	iron-sulfur transferase activity
FLK62_RS03920	COG0633	Ferredoxin
FLK62_RS03925	COG2975	iron-sulfur cluster assembly
FLK62_RS03935	COG1132	(ABC) transporter
FLK62_RS03950	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FLK62_RS03960	COG1271	oxidase subunit
FLK62_RS03965	COG1294	oxidase, subunit
FLK62_RS03980	COG0824	Thioesterase
FLK62_RS03985	COG0811	peptide transport
FLK62_RS03990	COG0848	biopolymer transport protein
FLK62_RS03995	COG3064	Membrane
FLK62_RS03995	COG3064	Membrane
FLK62_RS04000	COG0823	Involved in the tonB-independent uptake of proteins
FLK62_RS04010	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FLK62_RS04020	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FLK62_RS04035	COG1530	ribonuclease E activity
FLK62_RS04040	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FLK62_RS04050	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FLK62_RS04055	COG1137	ATPase activity
FLK62_RS04060	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FLK62_RS04070	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FLK62_RS04090	COG0747	negative chemotaxis
FLK62_RS04095	COG1760	l-serine dehydratase
FLK62_RS04095	COG1760	l-serine dehydratase
FLK62_RS04115	COG0058	SHG alpha-glucan phosphorylase activity
FLK62_RS04125	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FLK62_RS04130	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FLK62_RS04140	COG1477	protein flavinylation
FLK62_RS04145	COG2991	Protein conserved in bacteria
FLK62_RS04190	COG3116	cell division
FLK62_RS04195	COG0768	penicillin binding
FLK62_RS04200	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FLK62_RS04215	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FLK62_RS04225	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FLK62_RS04230	COG0772	Belongs to the SEDS family
FLK62_RS04255	COG0849	cell division
FLK62_RS04280	COG0681	Belongs to the peptidase S26 family
FLK62_RS04300	COG1943	Transposase
FLK62_RS04305	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FLK62_RS04315	COG0528	UMP kinase activity
FLK62_RS04330	COG1944	ATP diphosphatase activity
FLK62_RS04335	COG2252	PERMEase
FLK62_RS04340	COG0628	permease
FLK62_RS04345	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FLK62_RS04360	COG3978	acetolactate synthase activity
FLK62_RS04395	COG0494	nUDIX hydrolase
FLK62_RS04400	COG1238	metal cluster binding
FLK62_RS04405	COG2116	formate transmembrane transporter activity
FLK62_RS04410	COG1882	Formate acetyltransferase
FLK62_RS04415	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FLK62_RS04420	COG2268	Band 7 protein
FLK62_RS04430	COG0786	glutamate:sodium symporter activity
FLK62_RS04435	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FLK62_RS04440	COG3105	Protein conserved in bacteria
FLK62_RS04460	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FLK62_RS04465	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FLK62_RS04470	COG1840	ABC-type Fe3 transport system, periplasmic component
FLK62_RS04485	COG0305	Participates in initiation and elongation during chromosome replication
FLK62_RS04500	COG1509	lysine 2,3-aminomutase activity
FLK62_RS04520	COG3074	FtsZ-dependent cytokinesis
FLK62_RS04525	COG1435	thymidine kinase activity
FLK62_RS04530	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FLK62_RS04535	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FLK62_RS04535	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FLK62_RS04540	COG0670	Belongs to the BI1 family
FLK62_RS04545	COG0542	response to heat
FLK62_RS04550	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FLK62_RS04555	COG0739	heme binding
FLK62_RS04560	COG1121	(ABC) transporter
FLK62_RS04565	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FLK62_RS04570	COG0121	glutamine amidotransferase
FLK62_RS04575	COG3684	Belongs to the aldolase LacD family
FLK62_RS04590	COG3716	PTS system mannose fructose sorbose family IID component
FLK62_RS04600	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FLK62_RS04605	COG2222	sugar isomerase
FLK62_RS04610	COG1349	DNA-binding transcription factor activity
FLK62_RS04640	COG0195	Participates in both transcription termination and antitermination
FLK62_RS04645	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FLK62_RS04670	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FLK62_RS04675	COG2190	(PTS) system
FLK62_RS04680	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FLK62_RS04690	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FLK62_RS04715	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FLK62_RS04720	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FLK62_RS04725	COG1862	Preprotein translocase
FLK62_RS04730	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FLK62_RS04755	COG3101	peptidyl-lysine hydroxylation
FLK62_RS04760	COG0778	Nitroreductase
FLK62_RS04770	COG0859	PFAM glycosyl transferase family 9
FLK62_RS04785	COG1090	epimerase
FLK62_RS04800	COG3118	belongs to the thioredoxin family
FLK62_RS04805	COG0492	ferredoxin-NADP+ reductase activity
FLK62_RS04810	COG0463	Glycosyl transferase, family 2
FLK62_RS04815	COG1534	Rna-binding protein
FLK62_RS04855	COG0475	glutathione-regulated potassium exporter activity
FLK62_RS04855	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FLK62_RS04860	COG2255	four-way junction helicase activity
FLK62_RS04865	COG4166	transmembrane transport
FLK62_RS04870	COG0601	transmembrane transport
FLK62_RS04875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FLK62_RS04880	COG4172	Belongs to the ABC transporter superfamily
FLK62_RS04890	COG2909	trisaccharide binding
FLK62_RS04900	COG3071	HemY protein
FLK62_RS04905	COG2959	enzyme of heme biosynthesis
FLK62_RS04915	COG0181	hydroxymethylbilane synthase activity
FLK62_RS04920	COG1115	amino acid carrier protein
FLK62_RS04930	COG1025	Belongs to the peptidase M16 family
FLK62_RS04940	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FLK62_RS04955	COG1199	ATP-dependent helicase activity
FLK62_RS04965	COG0583	DNA-binding transcription factor activity
FLK62_RS04975	COG3306	glycosyltransferase involved in LPS biosynthesis
FLK62_RS04980	COG1442	glycosyl transferase family 8
FLK62_RS04985	COG1216	Glycosyl transferase, family 2
FLK62_RS05020	COG1218	3'(2'),5'-bisphosphate nucleotidase
FLK62_RS05025	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FLK62_RS05030	COG0363	glucosamine-6-phosphate deaminase activity
FLK62_RS05035	COG4804	nuclease activity
FLK62_RS05040	COG3759	membrane
FLK62_RS05055	COG1943	Transposase
FLK62_RS05070	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FLK62_RS05075	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FLK62_RS05095	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FLK62_RS05110	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FLK62_RS05115	COG3023	N-Acetylmuramoyl-L-alanine amidase
FLK62_RS05120	COG2431	L-lysine efflux transmembrane transporter activity
FLK62_RS05140	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FLK62_RS05145	COG4149	molybdate abc transporter
FLK62_RS05150	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FLK62_RS05160	COG3676	manually curated
FLK62_RS05165	COG2814	Major facilitator Superfamily
FLK62_RS05170	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FLK62_RS05175	COG2976	Protein conserved in bacteria
FLK62_RS05185	COG1177	transmembrane transport
FLK62_RS05190	COG1176	ABC-type spermidine putrescine transport system, permease component I
FLK62_RS05195	COG3842	ATPase activity
FLK62_RS05205	COG0676	glucose-6-phosphate 1-epimerase activity
FLK62_RS05210	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FLK62_RS05215	COG3068	Protein conserved in bacteria
FLK62_RS05250	COG1349	DNA-binding transcription factor activity
FLK62_RS05270	COG0305	Participates in initiation and elongation during chromosome replication
FLK62_RS05300	COG0629	single-stranded DNA binding
FLK62_RS05520	COG4104	PAAR repeat-containing protein
FLK62_RS05520	COG3209	COG3209 Rhs family protein
FLK62_RS05535	COG0786	glutamate:sodium symporter activity
FLK62_RS05550	COG0640	Transcriptional regulator
FLK62_RS05565	COG2826	transposase and inactivated derivatives, IS30 family
FLK62_RS05575	COG3692	DNA binding
FLK62_RS05650	COG3692	DNA binding
FLK62_RS05740	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FLK62_RS05780	COG3728	DNA packaging
FLK62_RS05860	COG0012	GTP binding
FLK62_RS05870	COG0582	viral genome integration into host DNA
FLK62_RS05885	COG2364	Membrane
FLK62_RS05890	COG4591	ABC-type transport system involved in lipoprotein release permease component
FLK62_RS05895	COG2032	superoxide dismutase activity
FLK62_RS05900	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FLK62_RS05905	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FLK62_RS05920	COG0783	Belongs to the Dps family
FLK62_RS05935	COG0792	nuclease activity
FLK62_RS05940	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FLK62_RS05945	COG2823	Periplasmic or secreted lipoprotein
FLK62_RS05950	COG1127	ABC transporter
FLK62_RS05955	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FLK62_RS05960	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FLK62_RS05965	COG2854	intermembrane phospholipid transfer
FLK62_RS05975	COG5007	Belongs to the BolA IbaG family
FLK62_RS05985	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FLK62_RS05990	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FLK62_RS05995	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FLK62_RS05995	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FLK62_RS06010	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FLK62_RS06040	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FLK62_RS06060	COG1595	DNA-templated transcription, initiation
FLK62_RS06065	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
FLK62_RS06070	COG3025	triphosphatase activity
FLK62_RS06095	COG2867	negative regulation of translational initiation
FLK62_RS06100	COG2914	Belongs to the UPF0125 (RnfH) family
FLK62_RS06115	COG0564	pseudouridine synthase activity
FLK62_RS06120	COG3098	single-species biofilm formation
FLK62_RS06135	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FLK62_RS06155	COG0251	oxidation-reduction process
FLK62_RS06165	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FLK62_RS06170	COG1286	toxin biosynthetic process
FLK62_RS06175	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FLK62_RS06190	COG0791	NLP P60 protein
FLK62_RS06200	COG0072	phenylalanine-tRNA ligase activity
FLK62_RS06200	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FLK62_RS06210	COG1392	Phosphate transport regulator
FLK62_RS06215	COG0306	phosphate transporter
FLK62_RS06220	COG4991	sh3 domain protein
FLK62_RS06235	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FLK62_RS06240	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FLK62_RS06250	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FLK62_RS06255	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FLK62_RS06260	COG0508	dehydrogenase complex catalyzes the overall conversion of
FLK62_RS06265	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FLK62_RS06270	COG2183	response to ionizing radiation
FLK62_RS06275	COG3302	dmso reductase anchor subunit
FLK62_RS06280	COG3302	dmso reductase anchor subunit
FLK62_RS06285	COG0437	4 iron, 4 sulfur cluster binding
FLK62_RS06290	COG0697	spore germination
FLK62_RS06295	COG2949	membrane
FLK62_RS06320	COG0784	Response regulator, receiver
FLK62_RS06320	COG5002	protein histidine kinase activity
FLK62_RS06320	COG2198	Histidine kinase
FLK62_RS06325	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FLK62_RS06350	COG4785	May be involved in cell division
FLK62_RS06355	COG0513	Belongs to the DEAD box helicase family
FLK62_RS06365	COG0590	tRNA wobble adenosine to inosine editing
FLK62_RS06370	COG3092	negative regulation of chromosome organization
FLK62_RS06385	COG1607	acyl-coa hydrolase
FLK62_RS06390	COG2350	Protein conserved in bacteria
FLK62_RS06400	COG0658	competence protein
FLK62_RS06400	COG2333	competence protein COMEC
FLK62_RS06405	COG0589	response to stress
FLK62_RS06410	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FLK62_RS06420	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FLK62_RS06425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FLK62_RS06430	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FLK62_RS06435	COG0539	negative regulation of cytoplasmic translation
FLK62_RS06445	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
FLK62_RS06450	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FLK62_RS06460	COG0023	Translation Initiation Factor
FLK62_RS06465	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FLK62_RS06475	COG5295	Hep Hag repeat protein
FLK62_RS06480	COG0489	protein tyrosine kinase activity
FLK62_RS06485	COG4166	transmembrane transport
FLK62_RS06490	COG2095	MarC family integral membrane protein
FLK62_RS06495	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FLK62_RS06515	COG4211	Belongs to the binding-protein-dependent transport system permease family
FLK62_RS06520	COG1129	ABC transporter
FLK62_RS06525	COG1879	ABC-type sugar transport system periplasmic component
FLK62_RS06530	COG1444	tRNA N-acetyltransferase activity
FLK62_RS06540	COG3594	Acyltransferase
FLK62_RS06550	COG4974	Belongs to the 'phage' integrase family
FLK62_RS06635	COG4695	Portal protein
FLK62_RS06790	COG0314	molybdopterin synthase activity
FLK62_RS06795	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FLK62_RS06825	COG2363	Small membrane protein
FLK62_RS06835	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FLK62_RS06845	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FLK62_RS06855	COG0582	viral genome integration into host DNA
FLK62_RS06910	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FLK62_RS06920	COG2369	cell adhesion
FLK62_RS06960	COG2731	YhcH YjgK YiaL family protein
FLK62_RS06965	COG1737	Transcriptional regulator
FLK62_RS06975	COG2081	HI0933 family
FLK62_RS06990	COG1448	Aminotransferase
FLK62_RS07010	COG0285	dihydrofolate synthase activity
FLK62_RS07020	COG0625	glutathione transferase activity
FLK62_RS07025	COG2969	positive regulation of protein catabolic process
FLK62_RS07035	COG0857	belongs to the CobB CobQ family
FLK62_RS07035	COG0280	phosphate acetyltransferase
FLK62_RS07055	COG3328	transposase activity
FLK62_RS07115	COG1943	Transposase
FLK62_RS07135	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FLK62_RS07140	COG1846	Transcriptional regulator
FLK62_RS07140	COG1940	carbohydrate kinase activity
FLK62_RS07160	COG3264	Mechanosensitive ion channel
FLK62_RS07160	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FLK62_RS07165	COG0318	PFAM AMP-dependent synthetase and ligase
FLK62_RS07175	COG0596	Alpha beta hydrolase
FLK62_RS07180	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FLK62_RS07205	COG3093	addiction module antidote protein HigA
FLK62_RS07210	COG0513	Belongs to the DEAD box helicase family
FLK62_RS07220	COG1373	ATPase (AAA superfamily
FLK62_RS07225	COG0629	single-stranded DNA binding
FLK62_RS07230	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FLK62_RS07235	COG3112	Uncharacterised protein family (UPF0231)
FLK62_RS07265	COG0741	lytic transglycosylase activity
FLK62_RS07270	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FLK62_RS07275	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FLK62_RS07280	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FLK62_RS07285	COG1278	Cold shock
FLK62_RS07290	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FLK62_RS07295	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FLK62_RS07315	COG0564	pseudouridine synthase activity
FLK62_RS07335	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FLK62_RS07340	COG0732	type I restriction modification DNA specificity domain
FLK62_RS07345	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FLK62_RS07365	COG0006	proline dipeptidase activity
FLK62_RS07375	COG3956	TIGRFAM MazG family protein
FLK62_RS07380	COG0745	RESPONSE REGULATOR receiver
FLK62_RS07385	COG2205	protein histidine kinase activity
FLK62_RS07395	COG2814	Major facilitator Superfamily
FLK62_RS07415	COG0312	modulator of DNA gyrase
FLK62_RS07430	COG0425	Belongs to the sulfur carrier protein TusA family
FLK62_RS07435	COG3945	hemerythrin HHE cation binding domain
FLK62_RS07440	COG0187	DNA topoisomerase II activity
FLK62_RS07455	COG3021	interspecies interaction between organisms
FLK62_RS07470	COG1214	PFAM Peptidase M22, glycoprotease
FLK62_RS07475	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FLK62_RS07480	COG1674	ftsk spoiiie
FLK62_RS07485	COG1522	sequence-specific DNA binding
FLK62_RS07510	COG0037	tRNA processing
FLK62_RS07515	COG2056	Na+-H+ antiporter family
FLK62_RS07520	COG0708	Exodeoxyribonuclease III
FLK62_RS07545	COG4735	regulation of single-species biofilm formation
FLK62_RS07605	COG3955	Domain of unknown function (DUF1919)
FLK62_RS07610	COG0516	GMP reductase activity
FLK62_RS07610	COG0517	IMP dehydrogenase activity
FLK62_RS07620	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FLK62_RS07625	COG1523	belongs to the glycosyl hydrolase 13 family
FLK62_RS07630	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FLK62_RS07650	COG2864	formate dehydrogenase
FLK62_RS07655	COG0437	4 iron, 4 sulfur cluster binding
FLK62_RS07685	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FLK62_RS07690	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FLK62_RS07700	COG0561	phosphatase activity
FLK62_RS07710	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FLK62_RS07715	COG1494	fructose-1,6-bisphosphatase
FLK62_RS07730	COG3021	interspecies interaction between organisms
FLK62_RS07745	COG3691	Protein conserved in bacteria
FLK62_RS07750	COG0778	Nitroreductase
FLK62_RS07755	COG0617	tRNA 3'-terminal CCA addition
FLK62_RS07775	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
FLK62_RS07785	COG0189	ligase activity
FLK62_RS07795	COG1960	acyl-CoA dehydrogenase activity
FLK62_RS07805	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FLK62_RS07810	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FLK62_RS07815	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FLK62_RS07835	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FLK62_RS07840	COG3842	ATPase activity
FLK62_RS07855	COG3833	ABC-type maltose transport systems, permease component
FLK62_RS07860	COG1640	4-alpha-glucanotransferase
FLK62_RS07865	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FLK62_RS07870	COG0617	tRNA 3'-terminal CCA addition
FLK62_RS07875	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FLK62_RS07900	COG0494	nUDIX hydrolase
FLK62_RS07905	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FLK62_RS07910	COG4988	ABC transporter
FLK62_RS07920	COG2911	Protein conserved in bacteria
FLK62_RS07925	COG0729	surface antigen
FLK62_RS07930	COG2861	carbohydrate metabolic process
FLK62_RS07935	COG4942	peptidase
FLK62_RS07940	COG0318	PFAM AMP-dependent synthetase and ligase
FLK62_RS07950	COG3026	antisigma factor binding
FLK62_RS07960	COG0301	tRNA thio-modification
FLK62_RS07960	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FLK62_RS07965	COG0302	gtp cyclohydrolase
FLK62_RS07970	COG3642	lipopolysaccharide core region biosynthetic process
FLK62_RS07980	COG3083	sulfuric ester hydrolase activity
FLK62_RS07985	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FLK62_RS07990	COG0583	DNA-binding transcription factor activity
FLK62_RS08005	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FLK62_RS08005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FLK62_RS08010	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FLK62_RS08025	COG0303	'Molybdopterin
FLK62_RS08030	COG2095	MarC family integral membrane protein
FLK62_RS08045	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FLK62_RS08055	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FLK62_RS08080	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FLK62_RS08095	COG0586	Pfam SNARE associated Golgi protein
FLK62_RS08110	COG2840	Smr protein MutS2
FLK62_RS08115	COG0814	amino acid
FLK62_RS08120	COG0814	amino acid
FLK62_RS08130	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FLK62_RS08135	COG0785	Cytochrome C biogenesis protein
FLK62_RS08140	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FLK62_RS08140	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FLK62_RS08150	COG1595	DNA-templated transcription, initiation
FLK62_RS08290	COG3328	transposase activity
FLK62_RS08315	COG1783	phage Terminase large subunit
FLK62_RS08320	COG3728	DNA packaging
FLK62_RS08335	COG3772	lysozyme
FLK62_RS08420	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FLK62_RS08495	COG0629	single-stranded DNA binding
FLK62_RS08570	COG3328	transposase activity
FLK62_RS08575	COG3328	transposase activity
FLK62_RS08710	COG1783	phage Terminase large subunit
FLK62_RS08715	COG3728	DNA packaging
FLK62_RS08735	COG3772	lysozyme
FLK62_RS08830	COG1724	mRNA binding
FLK62_RS08835	COG1598	PFAM Uncharacterised protein family UPF0150
FLK62_RS08840	COG3422	double-strand break repair
FLK62_RS08860	COG0582	viral genome integration into host DNA
FLK62_RS08875	COG2951	lytic endotransglycosylase activity
FLK62_RS08880	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FLK62_RS08910	COG0058	SHG alpha-glucan phosphorylase activity
FLK62_RS08920	COG0567	Dehydrogenase, E1 component
FLK62_RS08925	COG0508	dehydrogenase complex catalyzes the overall conversion of
FLK62_RS08935	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FLK62_RS08940	COG0475	glutathione-regulated potassium exporter activity
FLK62_RS08940	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FLK62_RS08955	COG2852	Protein conserved in bacteria
FLK62_RS08965	COG3106	COG3106 Predicted ATPase
FLK62_RS08970	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FLK62_RS08975	COG0709	Synthesizes selenophosphate from selenide and ATP
FLK62_RS08980	COG3036	rescue of stalled ribosome
FLK62_RS08985	COG2226	methyltransferase
FLK62_RS09010	COG1368	sulfuric ester hydrolase activity
FLK62_RS09015	COG0633	Ferredoxin
FLK62_RS09015	COG3217	Mosc domain protein beta barrel domain protein
FLK62_RS09025	COG0142	geranyltranstransferase activity
FLK62_RS09040	COG0183	Belongs to the thiolase family
FLK62_RS09045	COG1556	Lactate utilization protein
FLK62_RS09050	COG1139	Iron-sulfur cluster binding protein
FLK62_RS09055	COG0247	lactate metabolic process
FLK62_RS09060	COG1620	l-lactate permease
FLK62_RS09065	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FLK62_RS09070	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FLK62_RS09075	COG0730	response to heat
FLK62_RS09080	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FLK62_RS09110	COG0495	leucyl-tRNA aminoacylation
FLK62_RS09115	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
FLK62_RS09120	COG1466	dna polymerase III delta subunit
FLK62_RS09125	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FLK62_RS09130	COG0237	dephospho-CoA kinase activity
FLK62_RS09135	COG1393	Belongs to the ArsC family
FLK62_RS09140	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FLK62_RS09150	COG0494	nUDIX hydrolase
FLK62_RS09170	COG4608	Belongs to the ABC transporter superfamily
FLK62_RS09175	COG0444	Belongs to the ABC transporter superfamily
FLK62_RS09180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FLK62_RS09185	COG0601	transmembrane transport
FLK62_RS09190	COG0747	negative chemotaxis
FLK62_RS09195	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FLK62_RS09210	COG1678	Uncharacterized ACR, COG1678
FLK62_RS09215	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FLK62_RS09220	COG3056	Lipoprotein
FLK62_RS09225	COG0271	Belongs to the BolA IbaG family
FLK62_RS09235	COG0564	pseudouridine synthase activity
FLK62_RS09240	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FLK62_RS09265	COG0196	riboflavin kinase activity
FLK62_RS09285	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FLK62_RS09290	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
FLK62_RS09345	COG3328	transposase activity
FLK62_RS09355	COG3077	Addiction module antitoxin, RelB DinJ family
FLK62_RS09435	COG3772	lysozyme
FLK62_RS09505	COG1028	Short-chain dehydrogenase reductase Sdr
FLK62_RS09510	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FLK62_RS09515	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FLK62_RS09520	COG0142	geranyltranstransferase activity
FLK62_RS09525	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FLK62_RS09530	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FLK62_RS09535	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FLK62_RS09540	COG0859	PFAM glycosyl transferase family 9
FLK62_RS09550	COG3061	Opacity-associated protein A
FLK62_RS09550	COG3266	domain, Protein
FLK62_RS09555	COG1555	photosystem II stabilization
FLK62_RS09565	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FLK62_RS09580	COG0084	hydrolase, TatD family'
FLK62_RS09590	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FLK62_RS09600	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FLK62_RS09615	COG2814	Major facilitator Superfamily
FLK62_RS09645	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FLK62_RS09680	COG1720	tRNA m6t6A37 methyltransferase activity
FLK62_RS09685	COG1575	Belongs to the MenA family. Type 1 subfamily
FLK62_RS09695	COG1663	tetraacyldisaccharide 4'-kinase activity
FLK62_RS09705	COG3721	Heme iron utilization protein
FLK62_RS09710	COG0748	coenzyme F420 binding
FLK62_RS09715	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FLK62_RS09720	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FLK62_RS09740	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FLK62_RS09745	COG4160	amino acid transport
FLK62_RS09750	COG4215	(ABC) transporter
FLK62_RS09755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FLK62_RS09760	COG1126	abc transporter atp-binding protein
FLK62_RS09765	COG0210	DNA helicase
FLK62_RS09780	COG2965	DNA replication, synthesis of RNA primer
FLK62_RS09790	COG0477	Major facilitator Superfamily
FLK62_RS09805	COG0537	adenosine 5'-monophosphoramidase activity
FLK62_RS09815	COG0316	Belongs to the HesB IscA family
FLK62_RS09815	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FLK62_RS09825	COG1805	sodium ion transport
FLK62_RS09830	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FLK62_RS09835	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FLK62_RS09845	COG2871	sodium ion transport
FLK62_RS09850	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
FLK62_RS09855	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
FLK62_RS09860	COG1178	ABC-type Fe3 transport system permease component
FLK62_RS09870	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FLK62_RS09875	COG0437	4 iron, 4 sulfur cluster binding
FLK62_RS09880	COG3301	Polysulphide reductase, NrfD
FLK62_RS09890	COG0560	Phosphoserine phosphatase
FLK62_RS09905	COG1162	GTPase activity
FLK62_RS09915	COG1121	(ABC) transporter
FLK62_RS09920	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FLK62_RS09925	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FLK62_RS09930	COG4316	Uncharacterized protein conserved in bacteria (DUF2251)
FLK62_RS09945	COG1396	sequence-specific DNA binding
FLK62_RS09950	COG1621	beta-fructofuranosidase activity
FLK62_RS09960	COG2824	Alkylphosphonate utilization operon protein PhnA
FLK62_RS09965	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FLK62_RS09970	COG1027	Aspartate ammonia-lyase
FLK62_RS09980	COG2027	D-alanyl-D-alanine carboxypeptidase
FLK62_RS09985	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FLK62_RS10005	COG0697	spore germination
FLK62_RS10015	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FLK62_RS10020	COG4608	Belongs to the ABC transporter superfamily
FLK62_RS10025	COG0444	Belongs to the ABC transporter superfamily
FLK62_RS10045	COG0788	formyltetrahydrofolate deformylase activity
FLK62_RS10055	COG1757	Na H antiporter
FLK62_RS10060	COG1138	Cytochrome C-type biogenesis protein
FLK62_RS10070	COG4235	cytochrome complex assembly
FLK62_RS10070	COG3088	subunit of a heme lyase
FLK62_RS10075	COG4235	cytochrome complex assembly
FLK62_RS10075	COG3088	subunit of a heme lyase
FLK62_RS10080	COG3842	ATPase activity
FLK62_RS10090	COG1840	ABC-type Fe3 transport system, periplasmic component
FLK62_RS10095	COG1858	cytochrome C peroxidase
FLK62_RS10100	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FLK62_RS10110	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FLK62_RS10135	COG1122	ATPase activity
FLK62_RS10240	COG0596	Alpha beta hydrolase
FLK62_RS10260	COG2190	(PTS) system
FLK62_RS10260	COG1263	PTS System
FLK62_RS10260	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FLK62_RS10280	COG0799	negative regulation of ribosome biogenesis
FLK62_RS10285	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FLK62_RS10290	COG0768	penicillin binding
FLK62_RS10295	COG0772	Belongs to the SEDS family
FLK62_RS10305	COG1686	Belongs to the peptidase S11 family
FLK62_RS10315	COG0321	lipoyl(octanoyl) transferase activity
FLK62_RS10360	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FLK62_RS10370	COG0018	arginyl-trna synthetase
FLK62_RS10375	COG3102	Protein conserved in bacteria
FLK62_RS10400	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FLK62_RS10405	COG1957	nucleoside hydrolase
FLK62_RS10405	COG1957	nucleoside hydrolase
FLK62_RS10410	COG1522	sequence-specific DNA binding
FLK62_RS10410	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FLK62_RS10430	COG0546	phosphoglycolate phosphatase activity
FLK62_RS10435	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FLK62_RS10460	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FLK62_RS10470	COG4168	peptide transport system, permease
FLK62_RS10475	COG4166	transmembrane transport
FLK62_RS10490	COG0747	negative chemotaxis
FLK62_RS10500	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FLK62_RS10505	COG1530	ribonuclease E activity
FLK62_RS10525	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FLK62_RS10535	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FLK62_RS10555	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FLK62_RS10565	COG2137	regulation of response to DNA damage stimulus
FLK62_RS10575	COG0551	DNA topoisomerase type I activity
FLK62_RS10580	COG0009	L-threonylcarbamoyladenylate synthase
FLK62_RS10610	COG2960	long-chain fatty acid transporting porin activity
FLK62_RS10625	COG0641	radical SAM
FLK62_RS10630	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FLK62_RS10640	COG1322	Protein conserved in bacteria
FLK62_RS10645	COG0512	Glutamine amidotransferase of anthranilate synthase
FLK62_RS10665	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FLK62_RS10675	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FLK62_RS10695	COG1702	phosphate starvation-inducible protein PhoH
FLK62_RS10700	COG4143	(ABC) transporter
FLK62_RS10705	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FLK62_RS10720	COG0436	Aminotransferase
FLK62_RS10725	COG1169	isochorismate synthase
FLK62_RS10730	COG0671	phosphoesterase, PA-phosphatase related
FLK62_RS10735	COG1940	carbohydrate kinase activity
FLK62_RS10750	COG0575	Belongs to the CDS family
FLK62_RS10755	COG0750	zinc metalloprotease
FLK62_RS10770	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FLK62_RS10775	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FLK62_RS10785	COG0460	homoserine dehydrogenase
FLK62_RS10785	COG0527	aspartate kinase activity
FLK62_RS10790	COG0083	homoserine kinase activity
FLK62_RS10795	COG0287	Prephenate dehydrogenase
FLK62_RS10795	COG1605	Chorismate mutase
FLK62_RS10800	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FLK62_RS10805	COG0859	PFAM glycosyl transferase family 9
FLK62_RS10810	COG2920	part of a sulfur-relay system
FLK62_RS10820	COG1115	amino acid carrier protein
FLK62_RS10825	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FLK62_RS10830	COG3683	transport system, periplasmic component
FLK62_RS10840	COG0339	signal peptide processing
FLK62_RS10845	COG1605	Chorismate mutase
FLK62_RS10845	COG0077	Prephenate dehydratase
FLK62_RS10860	COG0439	Biotin carboxylase
FLK62_RS10865	COG0511	ligase activity, forming carbon-carbon bonds
FLK62_RS10885	COG1399	metal-binding, possibly nucleic acid-binding protein
FLK62_RS10895	COG0416	fatty acid biosynthetic process
FLK62_RS10905	COG0076	glutamate decarboxylase activity
FLK62_RS10910	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FLK62_RS10920	COG1561	YicC-like family, N-terminal region
FLK62_RS10925	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FLK62_RS10930	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FLK62_RS10930	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FLK62_RS10935	COG2832	Protein of unknown function (DUF454)
FLK62_RS10940	COG0521	Mo-molybdopterin cofactor biosynthetic process
FLK62_RS10950	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FLK62_RS10960	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FLK62_RS10965	COG1194	a g-specific adenine glycosylase
FLK62_RS10990	COG0247	lactate metabolic process
FLK62_RS11000	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FLK62_RS11015	COG0564	pseudouridine synthase activity
FLK62_RS11020	COG0668	transmembrane transport
FLK62_RS11025	COG0501	Belongs to the peptidase M48B family
FLK62_RS11030	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FLK62_RS11110	COG0277	FAD linked oxidase domain protein
FLK62_RS11130	COG2610	gluconate transmembrane transporter activity
FLK62_RS11135	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FLK62_RS11140	COG3622	Belongs to the hyi family
FLK62_RS11145	COG0235	Class ii aldolase
FLK62_RS11150	COG3395	kinase activity
FLK62_RS11155	COG2084	Dehydrogenase
FLK62_RS11160	COG1349	DNA-binding transcription factor activity
FLK62_RS11170	COG0625	glutathione transferase activity
FLK62_RS11185	COG2177	Part of the ABC transporter FtsEX involved in
FLK62_RS11190	COG2884	Cell division ATP-binding protein ftsE
FLK62_RS11195	COG0552	protein localization to endoplasmic reticulum
FLK62_RS11200	COG0742	ribosomal rna small subunit methyltransferase
FLK62_RS11240	COG3550	peptidyl-serine autophosphorylation
FLK62_RS11260	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FLK62_RS11275	COG3381	protein complex oligomerization
FLK62_RS11290	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FLK62_RS11295	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FLK62_RS11300	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FLK62_RS11305	COG2731	YhcH YjgK YiaL family protein
FLK62_RS11315	COG1414	Transcriptional regulator
FLK62_RS11330	COG3084	Protein conserved in bacteria
FLK62_RS11335	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FLK62_RS11340	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FLK62_RS11345	COG1309	transcriptional regulator
FLK62_RS11350	COG0583	DNA-binding transcription factor activity
FLK62_RS11355	COG0730	response to heat
FLK62_RS11360	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FLK62_RS11370	COG3119	arylsulfatase activity
FLK62_RS11375	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FLK62_RS11385	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FLK62_RS11390	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FLK62_RS11395	COG3062	negative regulation of establishment of protein localization
FLK62_RS11405	COG0437	4 iron, 4 sulfur cluster binding
FLK62_RS11410	COG0348	domain, Protein
FLK62_RS11415	COG3043	anaerobic respiration
FLK62_RS11420	COG3005	denitrification pathway
FLK62_RS11425	COG1609	Transcriptional regulator
FLK62_RS11430	COG3265	gluconokinase activity
FLK62_RS11435	COG2610	gluconate transmembrane transporter activity
FLK62_RS11445	COG1312	Catalyzes the dehydration of D-mannonate
FLK62_RS11450	COG2186	Transcriptional regulator
FLK62_RS11455	COG1063	alcohol dehydrogenase
FLK62_RS11460	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FLK62_RS11465	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FLK62_RS11470	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FLK62_RS11475	COG1028	Short-chain dehydrogenase reductase Sdr
FLK62_RS11480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FLK62_RS11485	COG0800	Aldolase
FLK62_RS11490	COG1694	Mazg nucleotide pyrophosphohydrolase
FLK62_RS11510	COG0235	Class ii aldolase
FLK62_RS11515	COG3623	hexulose-6-phosphate isomerase
FLK62_RS11540	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
FLK62_RS11545	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FLK62_RS11565	COG0300	oxidoreductase activity
FLK62_RS11570	COG4232	protein-disulfide reductase activity
FLK62_RS11575	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FLK62_RS11580	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FLK62_RS11635	COG0354	folic acid binding
FLK62_RS11645	COG2995	paraquat-inducible protein a
FLK62_RS11660	COG1388	LysM domain
FLK62_RS11660	COG4942	peptidase
FLK62_RS11665	COG4942	peptidase
FLK62_RS11665	COG1388	LysM domain
FLK62_RS11670	COG1238	metal cluster binding
FLK62_RS11675	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FLK62_RS11705	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FLK62_RS11720	COG0470	DNA polymerase III
FLK62_RS11725	COG0606	chelatase, subunit chli
FLK62_RS11745	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FLK62_RS11750	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FLK62_RS11760	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FLK62_RS11760	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FLK62_RS11765	COG3715	PTS system
FLK62_RS11770	COG3716	PTS system mannose fructose sorbose family IID component
FLK62_RS11780	COG1482	cell wall glycoprotein biosynthetic process
FLK62_RS11785	COG1129	ABC transporter
FLK62_RS11790	COG1172	Belongs to the binding-protein-dependent transport system permease family
FLK62_RS11795	COG1879	ABC-type sugar transport system periplasmic component
FLK62_RS11810	COG1733	regulation of RNA biosynthetic process
FLK62_RS11825	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FLK62_RS11875	COG2259	Doxx family
FLK62_RS11895	COG0791	NLP P60 protein
FLK62_RS11905	COG3381	protein complex oligomerization
FLK62_RS11940	COG1022	Amp-dependent synthetase and ligase
FLK62_RS11945	COG2927	DNA polymerase III (CHI subunit)
FLK62_RS11965	COG2017	converts alpha-aldose to the beta-anomer
FLK62_RS11980	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FLK62_RS12005	COG2801	Transposase and inactivated derivatives
FLK62_RS12015	COG0037	tRNA processing
FLK62_RS12045	COG2878	Part of a membrane complex involved in electron transport
FLK62_RS12050	COG4656	Part of a membrane complex involved in electron transport
FLK62_RS12075	COG1943	Transposase
FLK62_RS12085	COG1560	Kdo2-lipid A biosynthetic process
FLK62_RS12090	COG2226	methyltransferase
FLK62_RS12095	COG1252	NADH dehydrogenase
FLK62_RS12100	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FLK62_RS12105	COG0402	S-adenosylhomocysteine deaminase activity
FLK62_RS12110	COG4591	ABC-type transport system involved in lipoprotein release permease component
FLK62_RS12115	COG1136	(ABC) transporter
FLK62_RS12120	COG0288	reversible hydration of carbon dioxide
FLK62_RS12125	COG4221	oxidoreductase activity
FLK62_RS12135	COG0754	glutathionylspermidine amidase activity
FLK62_RS12140	COG2252	PERMEase
FLK62_RS12155	COG0330	HflC and HflK could
FLK62_RS12160	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FLK62_RS12165	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FLK62_RS12170	COG1643	Atp-dependent helicase
FLK62_RS12205	COG1074	ATP-dependent DNA helicase activity
FLK62_RS12250	COG3328	transposase activity
FLK62_RS12255	COG0174	glutamine synthetase
FLK62_RS12260	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FLK62_RS12270	COG1879	ABC-type sugar transport system periplasmic component
FLK62_RS12275	COG1172	Belongs to the binding-protein-dependent transport system permease family
FLK62_RS12295	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FLK62_RS12320	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FLK62_RS12340	COG0471	metal ion transport
FLK62_RS12340	COG0490	domain, Protein
FLK62_RS12375	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FLK62_RS12385	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FLK62_RS12395	COG0089	rRNA binding
FLK62_RS12410	COG0051	transcription antitermination factor activity, RNA binding
FLK62_RS12440	COG0019	diaminopimelate decarboxylase activity
FLK62_RS12445	COG0814	amino acid
FLK62_RS12460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FLK62_RS12465	COG1966	Carbon starvation protein
FLK62_RS12490	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FLK62_RS12515	COG0024	Methionine aminopeptidase
FLK62_RS12520	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FLK62_RS12525	COG1349	DNA-binding transcription factor activity
FLK62_RS12550	COG3111	PFAM Bacterial OB fold (BOF) protein
FLK62_RS12555	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FLK62_RS12560	COG2850	peptidyl-arginine hydroxylation
FLK62_RS12565	COG4285	Biotin-protein ligase, N terminal
FLK62_RS12570	COG1268	BioY protein
FLK62_RS12575	COG0561	phosphatase activity
FLK62_RS12580	COG1040	competence protein
FLK62_RS12585	COG0084	hydrolase, TatD family'
FLK62_RS12590	COG0557	exoribonuclease II activity
FLK62_RS12595	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane