locus-tag	class	description
AOZ07_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AOZ07_RS00010	COG0592	DNA-directed DNA polymerase activity
AOZ07_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AOZ07_RS00020	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
AOZ07_RS00025	COG0187	DNA topoisomerase II activity
AOZ07_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AOZ07_RS00035	COG3266	domain, Protein
AOZ07_RS00060	COG0385	Bile acid
AOZ07_RS00090	COG0583	DNA-binding transcription factor activity
AOZ07_RS00095	COG2076	Multidrug Resistance protein
AOZ07_RS00105	COG3764	Sortase (surface protein transpeptidase)
AOZ07_RS00115	COG2815	serine threonine protein kinase
AOZ07_RS00115	COG0515	serine threonine protein kinase
AOZ07_RS00120	COG0515	serine threonine protein kinase
AOZ07_RS00125	COG0768	penicillin binding
AOZ07_RS00140	COG1716	ATPase activity
AOZ07_RS00160	COG1609	Transcriptional regulator
AOZ07_RS00165	COG1957	nucleoside hydrolase
AOZ07_RS00170	COG0412	Dienelactone hydrolase
AOZ07_RS00185	COG1024	Enoyl-CoA hydratase
AOZ07_RS00195	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AOZ07_RS00200	COG0561	phosphatase activity
AOZ07_RS00215	COG2211	Major facilitator Superfamily
AOZ07_RS00220	COG4948	Mandelate Racemase Muconate Lactonizing
AOZ07_RS00225	COG1175	transmembrane transport
AOZ07_RS00230	COG0395	ABC-type sugar transport system, permease component
AOZ07_RS00235	COG0673	inositol 2-dehydrogenase activity
AOZ07_RS00265	COG0673	inositol 2-dehydrogenase activity
AOZ07_RS00270	COG1609	Transcriptional regulator
AOZ07_RS00290	COG0477	Major facilitator Superfamily
AOZ07_RS00295	COG2233	PERMEase
AOZ07_RS00300	COG0352	thiamine-phosphate diphosphorylase activity
AOZ07_RS00300	COG0351	phosphomethylpyrimidine kinase
AOZ07_RS00300	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AOZ07_RS00305	COG0352	thiamine-phosphate diphosphorylase activity
AOZ07_RS00310	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AOZ07_RS00315	COG1725	Transcriptional regulator
AOZ07_RS00325	COG1012	belongs to the aldehyde dehydrogenase family
AOZ07_RS00330	COG0833	amino acid
AOZ07_RS00335	COG0033	Phosphoglucomutase
AOZ07_RS00345	COG3104	oligopeptide transport
AOZ07_RS00350	COG0154	amidase activity
AOZ07_RS00370	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AOZ07_RS00375	COG0561	phosphatase activity
AOZ07_RS00410	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AOZ07_RS00415	COG2027	D-alanyl-D-alanine carboxypeptidase
AOZ07_RS00425	COG0037	tRNA processing
AOZ07_RS00435	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AOZ07_RS00440	COG0302	gtp cyclohydrolase
AOZ07_RS00450	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AOZ07_RS00475	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AOZ07_RS00540	COG3590	peptidase
AOZ07_RS00545	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AOZ07_RS00585	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AOZ07_RS00605	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
AOZ07_RS00610	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AOZ07_RS00635	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AOZ07_RS00645	COG1395	domain, Protein
AOZ07_RS00685	COG0488	(ABC) transporter
AOZ07_RS00690	COG2226	methyltransferase
AOZ07_RS00705	COG1309	transcriptional regulator
AOZ07_RS00710	COG0702	epimerase
AOZ07_RS00740	COG1937	Protein conserved in bacteria
AOZ07_RS00745	COG0730	response to heat
AOZ07_RS00770	COG0277	FAD linked oxidase domain protein
AOZ07_RS00790	COG0531	amino acid
AOZ07_RS00820	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AOZ07_RS00845	COG1690	Belongs to the RtcB family
AOZ07_RS00890	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AOZ07_RS00895	COG0246	Mannitol dehydrogenase
AOZ07_RS00900	COG2814	Major facilitator Superfamily
AOZ07_RS00905	COG1349	DNA-binding transcription factor activity
AOZ07_RS00910	COG1070	Carbohydrate kinase
AOZ07_RS00915	COG0584	glycerophosphoryl diester phosphodiesterase
AOZ07_RS00940	COG4122	O-methyltransferase activity
AOZ07_RS00965	COG2252	PERMEase
AOZ07_RS01035	COG1960	acyl-CoA dehydrogenase activity
AOZ07_RS01055	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AOZ07_RS01065	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AOZ07_RS01075	COG1653	transport
AOZ07_RS01080	COG1175	transmembrane transport
AOZ07_RS01085	COG0395	ABC-type sugar transport system, permease component
AOZ07_RS01090	COG1472	Belongs to the glycosyl hydrolase 3 family
AOZ07_RS01100	COG1131	(ABC) transporter
AOZ07_RS01105	COG1309	transcriptional regulator
AOZ07_RS01115	COG0357	Ribosomal RNA small subunit methyltransferase G
AOZ07_RS01115	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AOZ07_RS01120	COG0739	heme binding
AOZ07_RS01120	COG1196	nuclear chromosome segregation
AOZ07_RS01120	COG0741	lytic transglycosylase activity
AOZ07_RS01145	COG0745	RESPONSE REGULATOR receiver
AOZ07_RS01150	COG5002	protein histidine kinase activity
AOZ07_RS01170	COG1113	amino acid transport
AOZ07_RS01175	COG1435	thymidine kinase activity
AOZ07_RS01195	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AOZ07_RS01200	COG0004	ammonium transporteR
AOZ07_RS01225	COG0583	DNA-binding transcription factor activity
AOZ07_RS01235	COG0697	spore germination
AOZ07_RS01250	COG0277	FAD linked oxidase domain protein
AOZ07_RS01255	COG1070	Carbohydrate kinase
AOZ07_RS01265	COG1940	carbohydrate kinase activity
AOZ07_RS01265	COG1846	Transcriptional regulator
AOZ07_RS01280	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AOZ07_RS01315	COG0028	Belongs to the TPP enzyme family
AOZ07_RS01425	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AOZ07_RS01515	COG1132	(ABC) transporter
AOZ07_RS01520	COG1132	(ABC) transporter
AOZ07_RS01530	COG4584	PFAM Integrase catalytic
AOZ07_RS01620	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AOZ07_RS01625	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AOZ07_RS01625	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AOZ07_RS01625	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AOZ07_RS01635	COG1349	DNA-binding transcription factor activity
AOZ07_RS01640	COG1832	CoA-binding protein
AOZ07_RS01645	COG2873	o-acetylhomoserine
AOZ07_RS01650	COG0406	alpha-ribazole phosphatase activity
AOZ07_RS01660	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AOZ07_RS01670	COG0477	Major facilitator Superfamily
AOZ07_RS01680	COG1115	amino acid carrier protein
AOZ07_RS01685	COG1802	Transcriptional regulator
AOZ07_RS01690	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AOZ07_RS01700	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AOZ07_RS01705	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AOZ07_RS01715	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AOZ07_RS01720	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AOZ07_RS01740	COG0405	Gamma-glutamyltransferase
AOZ07_RS01745	COG0702	epimerase
AOZ07_RS01750	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AOZ07_RS01755	COG2011	ABC-type metal ion transport system permease component
AOZ07_RS01760	COG1464	Belongs to the NlpA lipoprotein family
AOZ07_RS01765	COG1960	acyl-CoA dehydrogenase activity
AOZ07_RS01775	COG1832	CoA-binding protein
AOZ07_RS01780	COG2315	Protein conserved in bacteria
AOZ07_RS01790	COG0737	Belongs to the 5'-nucleotidase family
AOZ07_RS01805	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ07_RS01810	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOZ07_RS01815	COG4592	Periplasmic binding protein
AOZ07_RS01825	COG2824	Alkylphosphonate utilization operon protein PhnA
AOZ07_RS01835	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOZ07_RS01845	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AOZ07_RS01860	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AOZ07_RS01865	COG0047	phosphoribosylformylglycinamidine synthase activity
AOZ07_RS01870	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AOZ07_RS01875	COG3012	SEC-C Motif Domain Protein
AOZ07_RS01890	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AOZ07_RS01910	COG2318	DinB family
AOZ07_RS01920	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AOZ07_RS01925	COG2851	Citrate transporter
AOZ07_RS01930	COG3290	protein histidine kinase activity
AOZ07_RS01935	COG4565	transcriptional regulatory protein
AOZ07_RS01970	COG0477	Major facilitator Superfamily
AOZ07_RS01975	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AOZ07_RS01985	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AOZ07_RS02040	COG0406	alpha-ribazole phosphatase activity
AOZ07_RS02050	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AOZ07_RS02065	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AOZ07_RS02075	COG4133	protoheme IX ABC transporter activity
AOZ07_RS02100	COG0542	response to heat
AOZ07_RS02105	COG2197	response regulator
AOZ07_RS02110	COG4585	Histidine kinase
AOZ07_RS02160	COG0351	phosphomethylpyrimidine kinase
AOZ07_RS02180	COG1121	(ABC) transporter
AOZ07_RS02195	COG0343	queuine tRNA-ribosyltransferase activity
AOZ07_RS02210	COG2814	Major facilitator Superfamily
AOZ07_RS02225	COG0564	pseudouridine synthase activity
AOZ07_RS02230	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AOZ07_RS02235	COG1201	RNA secondary structure unwinding
AOZ07_RS02260	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AOZ07_RS02265	COG0671	phosphoesterase, PA-phosphatase related
AOZ07_RS02270	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AOZ07_RS02290	COG0824	Thioesterase
AOZ07_RS02295	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AOZ07_RS02310	COG3485	protocatechuate 3,4-dioxygenase
AOZ07_RS02315	COG3485	protocatechuate 3,4-dioxygenase
AOZ07_RS02330	COG2814	Major facilitator Superfamily
AOZ07_RS02335	COG0183	Belongs to the thiolase family
AOZ07_RS02345	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AOZ07_RS02350	COG1414	Transcriptional regulator
AOZ07_RS02375	COG0521	Mo-molybdopterin cofactor biosynthetic process
AOZ07_RS02375	COG0315	cyclic pyranopterin monophosphate synthase activity
AOZ07_RS02380	COG0315	cyclic pyranopterin monophosphate synthase activity
AOZ07_RS02405	COG1473	amidohydrolase
AOZ07_RS02425	COG2378	regulation of single-species biofilm formation
AOZ07_RS02430	COG2318	DinB family
AOZ07_RS02445	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AOZ07_RS02470	COG0746	molybdenum cofactor guanylyltransferase activity
AOZ07_RS02490	COG0584	glycerophosphoryl diester phosphodiesterase
AOZ07_RS02505	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AOZ07_RS02510	COG2205	protein histidine kinase activity
AOZ07_RS02515	COG0745	RESPONSE REGULATOR receiver
AOZ07_RS02535	COG1132	(ABC) transporter
AOZ07_RS02540	COG1309	transcriptional regulator
AOZ07_RS02545	COG1511	domain protein
AOZ07_RS02575	COG2723	6-phospho-beta-galactosidase activity
AOZ07_RS02600	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
AOZ07_RS02610	COG0596	Alpha beta hydrolase
AOZ07_RS02610	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AOZ07_RS02620	COG1959	2 iron, 2 sulfur cluster binding
AOZ07_RS02635	COG0514	ATP-dependent DNA helicase (RecQ)
AOZ07_RS02650	COG1505	serine-type exopeptidase activity
AOZ07_RS02665	COG3321	synthase
AOZ07_RS02665	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ07_RS02665	COG0604	alcohol dehydrogenase
AOZ07_RS02670	COG1966	Carbon starvation protein
AOZ07_RS02685	COG0656	L-ascorbic acid biosynthetic process
AOZ07_RS02705	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AOZ07_RS02710	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AOZ07_RS02725	COG0588	phosphoglycerate mutase activity
AOZ07_RS02740	COG5002	protein histidine kinase activity
AOZ07_RS02760	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AOZ07_RS02760	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AOZ07_RS02765	COG0215	cysteine-tRNA ligase activity
AOZ07_RS02770	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AOZ07_RS02790	COG0277	FAD linked oxidase domain protein
AOZ07_RS02885	COG0629	single-stranded DNA binding
AOZ07_RS03135	COG3858	chitin binding
AOZ07_RS03135	COG1388	LysM domain
AOZ07_RS03210	COG3842	ATPase activity
AOZ07_RS03235	COG2354	Protein conserved in bacteria
AOZ07_RS03270	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AOZ07_RS03285	COG0459	protein refolding
AOZ07_RS03300	COG2205	protein histidine kinase activity
AOZ07_RS03305	COG0745	RESPONSE REGULATOR receiver
AOZ07_RS03315	COG1278	Cold shock
AOZ07_RS03340	COG1388	LysM domain
AOZ07_RS03340	COG0791	NLP P60 protein
AOZ07_RS03350	COG1051	belongs to the nudix hydrolase family
AOZ07_RS03410	COG0045	succinate-CoA ligase (ADP-forming) activity
AOZ07_RS03420	COG0477	Major facilitator Superfamily
AOZ07_RS03430	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AOZ07_RS03455	COG1396	sequence-specific DNA binding
AOZ07_RS03470	COG0028	Belongs to the TPP enzyme family
AOZ07_RS03480	COG1802	Transcriptional regulator
AOZ07_RS03495	COG1012	belongs to the aldehyde dehydrogenase family
AOZ07_RS03500	COG1250	3-hydroxyacyl-CoA dehydrogenase
AOZ07_RS03520	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AOZ07_RS03525	COG0519	Catalyzes the synthesis of GMP from XMP
AOZ07_RS03540	COG0577	efflux transmembrane transporter activity
AOZ07_RS03540	COG1136	(ABC) transporter
AOZ07_RS03590	COG1295	ribonuclease BN
AOZ07_RS03600	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AOZ07_RS03610	COG3483	tryptophan 2,3-dioxygenase activity
AOZ07_RS03615	COG0431	NADPH-dependent FMN reductase
AOZ07_RS03620	COG3971	2-oxopent-4-enoate hydratase activity
AOZ07_RS03675	COG0477	Major facilitator Superfamily
AOZ07_RS03685	COG0138	bifunctional purine biosynthesis protein purh
AOZ07_RS03700	COG1122	ATPase activity
AOZ07_RS03705	COG1914	H( )-stimulated, divalent metal cation uptake system
AOZ07_RS03710	COG4336	lyase activity
AOZ07_RS03715	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AOZ07_RS03725	COG4770	biotin carboxylase activity
AOZ07_RS03730	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AOZ07_RS03735	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AOZ07_RS03745	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AOZ07_RS03760	COG2814	Major facilitator Superfamily
AOZ07_RS03770	COG2838	Isocitrate dehydrogenase
AOZ07_RS03775	COG4691	Plasmid stability protein
AOZ07_RS03780	COG1487	ribonuclease activity
AOZ07_RS03790	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AOZ07_RS03885	COG3708	Transcriptional regulator
AOZ07_RS03885	COG2207	Transcriptional regulator
AOZ07_RS03915	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AOZ07_RS03920	COG0477	Major facilitator Superfamily
AOZ07_RS03945	COG4585	Histidine kinase
AOZ07_RS03950	COG2197	response regulator
AOZ07_RS03955	COG2314	TM2 domain
AOZ07_RS03965	COG0477	Major facilitator Superfamily
AOZ07_RS03980	COG2197	response regulator
AOZ07_RS04005	COG0180	Tryptophanyl-tRNA synthetase
AOZ07_RS04015	COG0583	DNA-binding transcription factor activity
AOZ07_RS04030	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AOZ07_RS04045	COG2009	succinate dehydrogenase
AOZ07_RS04050	COG0662	Cupin 2, conserved barrel domain protein
AOZ07_RS04050	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AOZ07_RS04055	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AOZ07_RS04060	COG1012	belongs to the aldehyde dehydrogenase family
AOZ07_RS04070	COG1473	amidohydrolase
AOZ07_RS04070	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AOZ07_RS04075	COG1744	ABC transporter substrate-binding protein PnrA-like
AOZ07_RS04080	COG3845	ABC transporter
AOZ07_RS04085	COG4603	Belongs to the binding-protein-dependent transport system permease family
AOZ07_RS04090	COG1079	Belongs to the binding-protein-dependent transport system permease family
AOZ07_RS04110	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AOZ07_RS04115	COG3956	TIGRFAM MazG family protein
AOZ07_RS04120	COG0148	phosphopyruvate hydratase activity
AOZ07_RS04145	COG1252	NADH dehydrogenase
AOZ07_RS04160	COG0531	amino acid
AOZ07_RS04170	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AOZ07_RS04175	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AOZ07_RS04185	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AOZ07_RS04195	COG1331	Highly conserved protein containing a thioredoxin domain
AOZ07_RS04200	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AOZ07_RS04205	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AOZ07_RS04220	COG1051	belongs to the nudix hydrolase family
AOZ07_RS04240	COG0114	fumarate hydratase activity
AOZ07_RS04245	COG0288	reversible hydration of carbon dioxide
AOZ07_RS04255	COG1494	fructose-1,6-bisphosphatase
AOZ07_RS04265	COG1316	TRANSCRIPTIONal
AOZ07_RS04270	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AOZ07_RS04355	COG0714	Associated with various cellular activities
AOZ07_RS04360	COG0084	hydrolase, TatD family'
AOZ07_RS04365	COG3583	domain protein
AOZ07_RS04370	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AOZ07_RS04375	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AOZ07_RS04380	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AOZ07_RS04390	COG0488	(ABC) transporter
AOZ07_RS04400	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AOZ07_RS04405	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AOZ07_RS04415	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AOZ07_RS04420	COG0193	aminoacyl-tRNA hydrolase activity
AOZ07_RS04430	COG0822	iron-sulfur transferase activity
AOZ07_RS04435	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AOZ07_RS04460	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AOZ07_RS04465	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AOZ07_RS04480	COG0477	Major facilitator Superfamily
AOZ07_RS04495	COG4770	biotin carboxylase activity
AOZ07_RS04515	COG0424	maF-like protein
AOZ07_RS04520	COG2409	Drug exporters of the RND superfamily
AOZ07_RS04530	COG1823	symporter activity
AOZ07_RS04540	COG0346	lactoylglutathione lyase activity
AOZ07_RS04555	COG0714	Associated with various cellular activities
AOZ07_RS04575	COG0631	protein serine/threonine phosphatase activity
AOZ07_RS04600	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AOZ07_RS04605	COG3347	Dehydrogenase
AOZ07_RS04605	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ07_RS04630	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AOZ07_RS04645	COG1802	Transcriptional regulator
AOZ07_RS04660	COG0402	S-adenosylhomocysteine deaminase activity
AOZ07_RS04680	COG3314	Sporulation integral membrane protein YlbJ
AOZ07_RS04705	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AOZ07_RS04725	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AOZ07_RS04730	COG0154	amidase activity
AOZ07_RS04735	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AOZ07_RS04745	COG4977	sequence-specific DNA binding
AOZ07_RS04750	COG1335	isochorismatase
AOZ07_RS04780	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AOZ07_RS04785	COG1846	Transcriptional regulator
AOZ07_RS04790	COG2814	Major facilitator Superfamily
AOZ07_RS04795	COG0656	L-ascorbic acid biosynthetic process
AOZ07_RS04800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AOZ07_RS04820	COG1063	alcohol dehydrogenase
AOZ07_RS04830	COG1609	Transcriptional regulator
AOZ07_RS04835	COG1653	transport
AOZ07_RS04840	COG1175	transmembrane transport
AOZ07_RS04845	COG0395	ABC-type sugar transport system, permease component
AOZ07_RS04850	COG1228	amidohydrolase
AOZ07_RS04865	COG2813	Specifically methylates the guanine in position
AOZ07_RS04865	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AOZ07_RS04870	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AOZ07_RS04885	COG0456	acetyltransferase
AOZ07_RS04895	COG2873	o-acetylhomoserine
AOZ07_RS04900	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AOZ07_RS04925	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AOZ07_RS04930	COG0423	glycine-tRNA ligase activity
AOZ07_RS04945	COG2059	Chromate
AOZ07_RS04970	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AOZ07_RS04975	COG0358	DNA primase activity
AOZ07_RS05030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOZ07_RS05075	COG3486	L-lysine 6-monooxygenase (NADPH) activity
AOZ07_RS05080	COG0076	glutamate decarboxylase activity
AOZ07_RS05110	COG0438	transferase activity, transferring glycosyl groups
AOZ07_RS05130	COG0052	Belongs to the universal ribosomal protein uS2 family
AOZ07_RS05135	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AOZ07_RS05140	COG0528	UMP kinase activity
AOZ07_RS05145	COG0233	cytoplasmic translational termination
AOZ07_RS05150	COG0575	Belongs to the CDS family
AOZ07_RS05160	COG1846	Transcriptional regulator
AOZ07_RS05165	COG0697	spore germination
AOZ07_RS05170	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AOZ07_RS05180	COG3279	Response regulator of the LytR AlgR family
AOZ07_RS05185	COG3275	phosphorelay sensor kinase activity
AOZ07_RS05195	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AOZ07_RS05210	COG0022	dehydrogenase e1 component
AOZ07_RS05215	COG0508	dehydrogenase complex catalyzes the overall conversion of
AOZ07_RS05225	COG0601	transmembrane transport
AOZ07_RS05230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOZ07_RS05255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOZ07_RS05280	COG1960	acyl-CoA dehydrogenase activity
AOZ07_RS05285	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AOZ07_RS05290	COG0750	zinc metalloprotease
AOZ07_RS05310	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AOZ07_RS05335	COG0442	prolyl-tRNA aminoacylation
AOZ07_RS05355	COG0779	Required for maturation of 30S ribosomal subunits
AOZ07_RS05370	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AOZ07_RS05370	COG0481	GTPase activity
AOZ07_RS05375	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AOZ07_RS05415	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AOZ07_RS05430	COG0196	riboflavin kinase activity
AOZ07_RS05435	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AOZ07_RS05440	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AOZ07_RS05460	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AOZ07_RS05465	COG1304	FMN binding
AOZ07_RS05475	COG0765	amino acid transport
AOZ07_RS05495	COG0589	response to stress
AOZ07_RS05510	COG3181	Tripartite tricarboxylate transporter family receptor
AOZ07_RS05515	COG3290	protein histidine kinase activity
AOZ07_RS05520	COG4565	transcriptional regulatory protein
AOZ07_RS05530	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AOZ07_RS05535	COG0318	PFAM AMP-dependent synthetase and ligase
AOZ07_RS05540	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AOZ07_RS05545	COG0384	phenazine biosynthesis protein PhzF
AOZ07_RS05550	COG1609	Transcriptional regulator
AOZ07_RS05555	COG1621	beta-fructofuranosidase activity
AOZ07_RS05575	COG1064	alcohol dehydrogenase
AOZ07_RS05590	COG1185	polyribonucleotide nucleotidyltransferase activity
AOZ07_RS05595	COG2031	fatty acid transporter
AOZ07_RS05615	COG0612	Peptidase, M16
AOZ07_RS05630	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AOZ07_RS05645	COG1940	carbohydrate kinase activity
AOZ07_RS05660	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AOZ07_RS05690	COG1940	carbohydrate kinase activity
AOZ07_RS05695	COG0142	geranyltranstransferase activity
AOZ07_RS05700	COG1172	Belongs to the binding-protein-dependent transport system permease family
AOZ07_RS05705	COG1129	ABC transporter
AOZ07_RS05710	COG1879	ABC-type sugar transport system periplasmic component
AOZ07_RS05730	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AOZ07_RS05735	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AOZ07_RS05745	COG1125	glycine betaine transport
AOZ07_RS05745	COG0517	IMP dehydrogenase activity
AOZ07_RS05750	COG1174	glycine betaine transport
AOZ07_RS05790	COG4139	cobalamin transport
AOZ07_RS05795	COG1120	ATPase activity
AOZ07_RS05810	COG1674	ftsk spoiiie
AOZ07_RS05820	COG1058	Belongs to the CinA family
AOZ07_RS05820	COG1546	Belongs to the CinA family
AOZ07_RS05835	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AOZ07_RS05850	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AOZ07_RS05855	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AOZ07_RS05860	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AOZ07_RS05865	COG2813	Specifically methylates the guanine in position
AOZ07_RS05870	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AOZ07_RS05885	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AOZ07_RS05895	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AOZ07_RS05900	COG0131	Imidazoleglycerol-phosphate dehydratase
AOZ07_RS05905	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AOZ07_RS05910	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AOZ07_RS05935	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AOZ07_RS05940	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AOZ07_RS05945	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AOZ07_RS05950	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AOZ07_RS05955	COG0494	nUDIX hydrolase
AOZ07_RS05965	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AOZ07_RS05970	COG0072	phenylalanine-tRNA ligase activity
AOZ07_RS05970	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AOZ07_RS06000	COG2326	polyphosphate kinase activity
AOZ07_RS06020	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AOZ07_RS06025	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AOZ07_RS06030	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AOZ07_RS06035	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AOZ07_RS06040	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AOZ07_RS06045	COG1438	arginine binding
AOZ07_RS06060	COG0165	Argininosuccinate lyase
AOZ07_RS06070	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AOZ07_RS06080	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AOZ07_RS06105	COG0647	UMP catabolic process
AOZ07_RS06115	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AOZ07_RS06120	COG0497	DNA recombination
AOZ07_RS06125	COG0504	CTP synthase activity
AOZ07_RS06130	COG0494	nUDIX hydrolase
AOZ07_RS06135	COG4974	Belongs to the 'phage' integrase family
AOZ07_RS06145	COG3655	Transcriptional regulator
AOZ07_RS06160	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AOZ07_RS06165	COG2079	MmgE PrpD family protein
AOZ07_RS06170	COG2186	Transcriptional regulator
AOZ07_RS06180	COG4565	transcriptional regulatory protein
AOZ07_RS06185	COG3290	protein histidine kinase activity
AOZ07_RS06190	COG1301	dicarboxylic acid transport
AOZ07_RS06225	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AOZ07_RS06230	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AOZ07_RS06245	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AOZ07_RS06250	COG1160	GTP binding
AOZ07_RS06260	COG0384	phenazine biosynthesis protein PhzF
AOZ07_RS06265	COG0488	(ABC) transporter
AOZ07_RS06275	COG3189	MarR family transcriptional regulator
AOZ07_RS06280	COG1716	ATPase activity
AOZ07_RS06300	COG1192	Involved in chromosome partitioning
AOZ07_RS06305	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AOZ07_RS06315	COG1022	Amp-dependent synthetase and ligase
AOZ07_RS06335	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AOZ07_RS06340	COG2815	serine threonine protein kinase
AOZ07_RS06340	COG0515	serine threonine protein kinase
AOZ07_RS06390	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AOZ07_RS06395	COG2884	Cell division ATP-binding protein ftsE
AOZ07_RS06405	COG0739	heme binding
AOZ07_RS06405	COG0741	lytic transglycosylase activity
AOZ07_RS06405	COG1196	nuclear chromosome segregation
AOZ07_RS06410	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AOZ07_RS06425	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AOZ07_RS06430	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AOZ07_RS06435	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AOZ07_RS06435	COG1321	iron dependent repressor
AOZ07_RS06440	COG0483	inositol monophosphate 1-phosphatase activity
AOZ07_RS06450	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AOZ07_RS06455	COG1595	DNA-templated transcription, initiation
AOZ07_RS06470	COG0567	Dehydrogenase, E1 component
AOZ07_RS06470	COG0508	dehydrogenase complex catalyzes the overall conversion of
AOZ07_RS06475	COG1253	flavin adenine dinucleotide binding
AOZ07_RS06480	COG1253	flavin adenine dinucleotide binding
AOZ07_RS06485	COG1120	ATPase activity
AOZ07_RS06500	COG0735	belongs to the Fur family
AOZ07_RS06515	COG0537	adenosine 5'-monophosphoramidase activity
AOZ07_RS06520	COG1643	Atp-dependent helicase
AOZ07_RS06535	COG1125	glycine betaine transport
AOZ07_RS06535	COG0517	IMP dehydrogenase activity
AOZ07_RS06540	COG0456	acetyltransferase
AOZ07_RS06540	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AOZ07_RS06560	COG0018	arginyl-trna synthetase
AOZ07_RS06565	COG0019	diaminopimelate decarboxylase activity
AOZ07_RS06570	COG0460	homoserine dehydrogenase
AOZ07_RS06575	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AOZ07_RS06580	COG0083	homoserine kinase activity
AOZ07_RS06590	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AOZ07_RS06595	COG2890	protein-(glutamine-N5) methyltransferase activity
AOZ07_RS06600	COG0009	L-threonylcarbamoyladenylate synthase
AOZ07_RS06605	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AOZ07_RS06615	COG0356	it plays a direct role in the translocation of protons across the membrane
AOZ07_RS06620	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AOZ07_RS06625	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AOZ07_RS06630	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AOZ07_RS06635	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AOZ07_RS06640	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AOZ07_RS06645	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AOZ07_RS06650	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AOZ07_RS06660	COG1228	amidohydrolase
AOZ07_RS06665	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
AOZ07_RS06720	COG1335	isochorismatase
AOZ07_RS06725	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AOZ07_RS06730	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AOZ07_RS06740	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AOZ07_RS06745	COG1234	tRNA 3'-trailer cleavage
AOZ07_RS06750	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AOZ07_RS06755	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AOZ07_RS06775	COG2188	Transcriptional regulator
AOZ07_RS06780	COG1131	(ABC) transporter
AOZ07_RS06795	COG2176	DNA-directed DNA polymerase activity
AOZ07_RS06805	COG0420	3'-5' exonuclease activity
AOZ07_RS06810	COG0419	ATPase involved in DNA repair
AOZ07_RS06830	COG1609	Transcriptional regulator
AOZ07_RS06835	COG0366	Alpha amylase catalytic
AOZ07_RS06845	COG1175	transmembrane transport
AOZ07_RS06850	COG3833	ABC-type maltose transport systems, permease component
AOZ07_RS06865	COG0477	Major facilitator Superfamily
AOZ07_RS06875	COG0488	(ABC) transporter
AOZ07_RS06895	COG2186	Transcriptional regulator
AOZ07_RS06925	COG1012	belongs to the aldehyde dehydrogenase family
AOZ07_RS06930	COG1802	Transcriptional regulator
AOZ07_RS06945	COG0577	efflux transmembrane transporter activity
AOZ07_RS06945	COG1136	(ABC) transporter
AOZ07_RS06960	COG1132	(ABC) transporter
AOZ07_RS06965	COG1132	(ABC) transporter
AOZ07_RS06980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOZ07_RS06985	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOZ07_RS06990	COG1120	ATPase activity
AOZ07_RS07000	COG0129	dihydroxy-acid dehydratase activity
AOZ07_RS07020	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AOZ07_RS07025	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AOZ07_RS07035	COG1104	cysteine desulfurase activity
AOZ07_RS07045	COG2084	Dehydrogenase
AOZ07_RS07060	COG0477	Major facilitator Superfamily
AOZ07_RS07095	COG1846	Transcriptional regulator
AOZ07_RS07100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOZ07_RS07105	COG2197	response regulator
AOZ07_RS07140	COG1764	response to oxidative stress
AOZ07_RS07150	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AOZ07_RS07155	COG0667	Aldo Keto reductase
AOZ07_RS07165	COG0579	oxidoreductase
AOZ07_RS07170	COG0747	negative chemotaxis
AOZ07_RS07175	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AOZ07_RS07205	COG1846	Transcriptional regulator
AOZ07_RS07210	COG0702	epimerase
AOZ07_RS07225	COG0142	geranyltranstransferase activity
AOZ07_RS07235	COG1233	COG1233 Phytoene dehydrogenase and related
AOZ07_RS07255	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AOZ07_RS07265	COG0129	dihydroxy-acid dehydratase activity
AOZ07_RS07275	COG0440	acetolactate synthase activity
AOZ07_RS07280	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AOZ07_RS07315	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AOZ07_RS07360	COG1484	DNA-dependent DNA replication
AOZ07_RS07365	COG0463	Glycosyl transferase, family 2
AOZ07_RS07365	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AOZ07_RS07370	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AOZ07_RS07370	COG0463	Glycosyl transferase, family 2
AOZ07_RS07375	COG1432	Conserved Protein
AOZ07_RS07385	COG2197	response regulator
AOZ07_RS07390	COG4585	Histidine kinase
AOZ07_RS07395	COG0473	3-isopropylmalate dehydrogenase activity
AOZ07_RS07400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AOZ07_RS07405	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AOZ07_RS07415	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AOZ07_RS07430	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AOZ07_RS07435	COG1160	GTP binding
AOZ07_RS07440	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AOZ07_RS07445	COG1414	Transcriptional regulator
AOZ07_RS07450	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AOZ07_RS07455	COG0066	3-isopropylmalate dehydratase activity
AOZ07_RS07460	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AOZ07_RS07470	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AOZ07_RS07475	COG1181	Belongs to the D-alanine--D-alanine ligase family
AOZ07_RS07480	COG1316	TRANSCRIPTIONal
AOZ07_RS07485	COG1461	Dihydroxyacetone kinase
AOZ07_RS07495	COG0742	ribosomal rna small subunit methyltransferase
AOZ07_RS07510	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AOZ07_RS07515	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AOZ07_RS07525	COG1316	TRANSCRIPTIONal
AOZ07_RS07565	COG0463	Glycosyl transferase, family 2
AOZ07_RS07565	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AOZ07_RS07585	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AOZ07_RS07590	COG0571	ribonuclease III activity
AOZ07_RS07595	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AOZ07_RS07645	COG2814	Major facilitator Superfamily
AOZ07_RS07665	COG2755	lipolytic protein G-D-S-L family
AOZ07_RS07665	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AOZ07_RS07670	COG2094	Belongs to the DNA glycosylase MPG family
AOZ07_RS07730	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AOZ07_RS07740	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AOZ07_RS07745	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AOZ07_RS07755	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AOZ07_RS07760	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AOZ07_RS07765	COG2514	catechol 2,3-dioxygenase activity
AOZ07_RS07780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOZ07_RS07785	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOZ07_RS07810	COG2837	iron assimilation
AOZ07_RS07820	COG0672	)-iron permease
AOZ07_RS07825	COG0228	four-way junction DNA binding
AOZ07_RS07830	COG1837	Belongs to the UPF0109 family
AOZ07_RS07835	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AOZ07_RS07840	COG0336	Belongs to the RNA methyltransferase TrmD family
AOZ07_RS07845	COG0335	large ribosomal subunit rRNA binding
AOZ07_RS07850	COG0681	Belongs to the peptidase S26 family
AOZ07_RS07865	COG0681	Belongs to the peptidase S26 family
AOZ07_RS07870	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AOZ07_RS07880	COG2113	Glycine betaine
AOZ07_RS07885	COG4176	ABC-type proline glycine betaine transport system permease component
AOZ07_RS07890	COG4175	Glycine betaine
AOZ07_RS07890	COG0517	IMP dehydrogenase activity
AOZ07_RS07895	COG0792	nuclease activity
AOZ07_RS07905	COG0758	DNA mediated transformation
AOZ07_RS07905	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AOZ07_RS07910	COG4974	Belongs to the 'phage' integrase family
AOZ07_RS07930	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AOZ07_RS07935	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AOZ07_RS07950	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AOZ07_RS08005	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AOZ07_RS08015	COG1272	protein, Hemolysin III
AOZ07_RS08025	COG3265	gluconokinase activity
AOZ07_RS08030	COG2610	gluconate transmembrane transporter activity
AOZ07_RS08035	COG1802	Transcriptional regulator
AOZ07_RS08040	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AOZ07_RS08070	COG2130	NADP-dependent
AOZ07_RS08080	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AOZ07_RS08085	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AOZ07_RS08090	COG1045	serine acetyltransferase
AOZ07_RS08100	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AOZ07_RS08105	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AOZ07_RS08115	COG3022	response to hydroperoxide
AOZ07_RS08135	COG0242	peptide deformylase activity
AOZ07_RS08140	COG1960	acyl-CoA dehydrogenase activity
AOZ07_RS08190	COG0488	(ABC) transporter
AOZ07_RS08215	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ07_RS08220	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ07_RS08235	COG1119	ATPase activity
AOZ07_RS08280	COG0254	rRNA binding
AOZ07_RS08300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOZ07_RS08335	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ07_RS08345	COG0438	transferase activity, transferring glycosyl groups
AOZ07_RS08365	COG1914	H( )-stimulated, divalent metal cation uptake system
AOZ07_RS08370	COG0745	RESPONSE REGULATOR receiver
AOZ07_RS08375	COG0642	Histidine kinase
AOZ07_RS08385	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AOZ07_RS08400	COG1968	undecaprenyl-diphosphatase activity
AOZ07_RS08405	COG0215	cysteine-tRNA ligase activity
AOZ07_RS08415	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AOZ07_RS08420	COG1994	Peptidase M50
AOZ07_RS08420	COG0517	IMP dehydrogenase activity
AOZ07_RS08430	COG1222	aaa ATPase
AOZ07_RS08445	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
AOZ07_RS08450	COG0545	Peptidyl-prolyl cis-trans isomerase
AOZ07_RS08470	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AOZ07_RS08475	COG0805	protein transport
AOZ07_RS08485	COG1228	amidohydrolase
AOZ07_RS08490	COG1216	Glycosyl transferase, family 2
AOZ07_RS08525	COG0640	Transcriptional regulator
AOZ07_RS08560	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AOZ07_RS08565	COG1845	cytochrome c oxidase, subunit III
AOZ07_RS08570	COG2010	Cytochrome c
AOZ07_RS08575	COG0723	plastoquinol--plastocyanin reductase activity
AOZ07_RS08580	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AOZ07_RS08585	COG2188	Transcriptional regulator
AOZ07_RS08595	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AOZ07_RS08600	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AOZ07_RS08620	COG0167	dihydroorotate dehydrogenase activity
AOZ07_RS08630	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AOZ07_RS08635	COG1381	Involved in DNA repair and RecF pathway recombination
AOZ07_RS08640	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AOZ07_RS08650	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AOZ07_RS08660	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AOZ07_RS08680	COG0484	heat shock protein binding
AOZ07_RS08685	COG1420	regulation of RNA biosynthetic process
AOZ07_RS08705	COG0481	GTPase activity
AOZ07_RS08715	COG0268	Binds directly to 16S ribosomal RNA
AOZ07_RS08730	COG0658	competence protein
AOZ07_RS08730	COG2333	competence protein COMEC
AOZ07_RS08740	COG1307	EDD domain protein, DegV family
AOZ07_RS08745	COG0495	leucyl-tRNA aminoacylation
AOZ07_RS08755	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AOZ07_RS08760	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AOZ07_RS08785	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AOZ07_RS08795	COG1758	RNA polymerase activity
AOZ07_RS08800	COG0194	GDP metabolic process
AOZ07_RS08810	COG0284	orotidine-5'-phosphate decarboxylase activity
AOZ07_RS08815	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AOZ07_RS08820	COG0505	Belongs to the CarA family
AOZ07_RS08830	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AOZ07_RS08835	COG0540	Belongs to the ATCase OTCase family
AOZ07_RS08840	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AOZ07_RS08845	COG2318	DinB family
AOZ07_RS08850	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AOZ07_RS08855	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AOZ07_RS08865	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AOZ07_RS08870	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AOZ07_RS08875	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AOZ07_RS08880	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AOZ07_RS08890	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AOZ07_RS08895	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AOZ07_RS08910	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AOZ07_RS08920	COG1490	D-aminoacyl-tRNA deacylase activity
AOZ07_RS08925	COG1960	acyl-CoA dehydrogenase activity
AOZ07_RS08935	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AOZ07_RS08940	COG0124	histidyl-tRNA synthetase
AOZ07_RS08945	COG1196	nuclear chromosome segregation
AOZ07_RS08955	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AOZ07_RS08960	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AOZ07_RS08965	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AOZ07_RS08970	COG1862	Preprotein translocase
AOZ07_RS08975	COG2255	four-way junction helicase activity
AOZ07_RS08980	COG0632	four-way junction helicase activity
AOZ07_RS08985	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AOZ07_RS08990	COG0217	transcriptional regulatory protein
AOZ07_RS09030	COG2814	Major facilitator Superfamily
AOZ07_RS09040	COG0789	Transcriptional regulator
AOZ07_RS09050	COG2161	toxin-antitoxin pair type II binding
AOZ07_RS09055	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
AOZ07_RS09065	COG1131	(ABC) transporter
AOZ07_RS09075	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AOZ07_RS09085	COG0156	8-amino-7-oxononanoate synthase activity
AOZ07_RS09090	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AOZ07_RS09095	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AOZ07_RS09105	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AOZ07_RS09130	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AOZ07_RS09170	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOZ07_RS09180	COG2135	peptidase activity
AOZ07_RS09225	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AOZ07_RS09230	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AOZ07_RS09235	COG1780	Probably involved in ribonucleotide reductase function
AOZ07_RS09245	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AOZ07_RS09250	COG0028	Belongs to the TPP enzyme family
AOZ07_RS09260	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AOZ07_RS09280	COG1250	3-hydroxyacyl-CoA dehydrogenase
AOZ07_RS09285	COG0488	(ABC) transporter
AOZ07_RS09305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOZ07_RS09310	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AOZ07_RS09315	COG0829	nickel cation binding
AOZ07_RS09325	COG0830	nickel cation binding
AOZ07_RS09330	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
AOZ07_RS09335	COG0804	urea catabolic process
AOZ07_RS09340	COG0832	Belongs to the urease beta subunit family
AOZ07_RS09345	COG0831	urea catabolic process
AOZ07_RS09350	COG1053	succinate dehydrogenase
AOZ07_RS09355	COG0583	DNA-binding transcription factor activity
AOZ07_RS09380	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AOZ07_RS09385	COG1113	amino acid transport
AOZ07_RS09400	COG0598	Magnesium transport protein CorA
AOZ07_RS09410	COG0799	negative regulation of ribosome biogenesis
AOZ07_RS09420	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AOZ07_RS09430	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AOZ07_RS09435	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AOZ07_RS09440	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AOZ07_RS09450	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AOZ07_RS09455	COG1530	ribonuclease E activity
AOZ07_RS09480	COG0105	UTP biosynthetic process
AOZ07_RS09490	COG0285	dihydrofolate synthase activity
AOZ07_RS09495	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AOZ07_RS09500	COG3973	AAA domain
AOZ07_RS09505	COG4585	Histidine kinase
AOZ07_RS09510	COG2197	response regulator
AOZ07_RS09515	COG2409	Drug exporters of the RND superfamily
AOZ07_RS09525	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AOZ07_RS09545	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AOZ07_RS09545	COG1116	anion transmembrane transporter activity
AOZ07_RS09570	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AOZ07_RS09585	COG0525	valine-tRNA ligase activity
AOZ07_RS09600	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AOZ07_RS09605	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AOZ07_RS09610	COG0740	serine-type endopeptidase activity
AOZ07_RS09615	COG0740	serine-type endopeptidase activity
AOZ07_RS09620	COG0544	peptidyl-prolyl cis-trans isomerase activity
AOZ07_RS09650	COG0698	ribose 5-phosphate isomerase
AOZ07_RS09670	COG1946	Acyl-CoA thioesterase
AOZ07_RS09675	COG1017	nitric oxide dioxygenase activity
AOZ07_RS09675	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AOZ07_RS09695	COG0629	single-stranded DNA binding
AOZ07_RS09715	COG0738	Major facilitator superfamily
AOZ07_RS09725	COG1280	lysine exporter protein (LysE YggA)
AOZ07_RS09730	COG1122	ATPase activity
AOZ07_RS09735	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AOZ07_RS09740	COG1268	BioY protein
AOZ07_RS09755	COG2151	metal-sulfur cluster biosynthetic enzyme
AOZ07_RS09760	COG2151	metal-sulfur cluster biosynthetic enzyme
AOZ07_RS09765	COG0396	ATPase activity
AOZ07_RS09785	COG1131	(ABC) transporter
AOZ07_RS09800	COG0109	protoheme IX farnesyltransferase activity
AOZ07_RS09810	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AOZ07_RS09840	COG0058	SHG alpha-glucan phosphorylase activity
AOZ07_RS09845	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AOZ07_RS09855	COG0297	glycogen (starch) synthase activity
AOZ07_RS09865	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AOZ07_RS09870	COG0569	domain protein
AOZ07_RS09875	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AOZ07_RS09880	COG0149	triose-phosphate isomerase activity
AOZ07_RS09885	COG0126	phosphoglycerate kinase activity
AOZ07_RS09890	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AOZ07_RS09900	COG1481	regulation of sporulation
AOZ07_RS09905	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AOZ07_RS09910	COG1660	Displays ATPase and GTPase activities
AOZ07_RS09915	COG0322	excinuclease ABC activity
AOZ07_RS09945	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOZ07_RS09955	COG4106	trans-aconitate 2-methyltransferase activity
AOZ07_RS10005	COG0556	nucleotide-excision repair
AOZ07_RS10015	COG0237	dephospho-CoA kinase activity
AOZ07_RS10015	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AOZ07_RS10020	COG1739	Uncharacterized protein family UPF0029
AOZ07_RS10025	COG2813	Specifically methylates the guanine in position
AOZ07_RS10040	COG0539	negative regulation of cytoplasmic translation
AOZ07_RS10045	COG4552	Acetyltransferase involved in intracellular survival and related
AOZ07_RS10090	COG0469	pyruvate kinase activity
AOZ07_RS10100	COG0067	glutamate synthase
AOZ07_RS10100	COG0069	glutamate synthase activity
AOZ07_RS10100	COG0070	glutamate synthase
AOZ07_RS10110	COG0159	tryptophan synthase activity
AOZ07_RS10115	COG0133	tryptophan synthase activity
AOZ07_RS10120	COG0134	indole-3-glycerol-phosphate synthase activity
AOZ07_RS10140	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AOZ07_RS10160	COG0107	imidazoleglycerol-phosphate synthase activity
AOZ07_RS10165	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AOZ07_RS10170	COG0140	phosphoribosyl-ATP diphosphatase activity
AOZ07_RS10175	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AOZ07_RS10180	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AOZ07_RS10180	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AOZ07_RS10200	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AOZ07_RS10210	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AOZ07_RS10215	COG0242	peptide deformylase activity
AOZ07_RS10265	COG3135	benzoate transporter
AOZ07_RS10285	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AOZ07_RS10295	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AOZ07_RS10325	COG0183	Belongs to the thiolase family
AOZ07_RS10330	COG1024	Enoyl-CoA hydratase
AOZ07_RS10330	COG1250	3-hydroxyacyl-CoA dehydrogenase
AOZ07_RS10340	COG0667	Aldo Keto reductase
AOZ07_RS10345	COG0137	argininosuccinate synthase activity
AOZ07_RS10370	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AOZ07_RS10390	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AOZ07_RS10400	COG0531	amino acid
AOZ07_RS10405	COG0569	domain protein
AOZ07_RS10430	COG0756	dUTP diphosphatase activity
AOZ07_RS10460	COG0045	succinate-CoA ligase (ADP-forming) activity
AOZ07_RS10465	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AOZ07_RS10470	COG4988	ABC transporter
AOZ07_RS10475	COG1294	oxidase, subunit
AOZ07_RS10480	COG1271	oxidase subunit
AOZ07_RS10495	COG0187	DNA topoisomerase II activity
AOZ07_RS10505	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AOZ07_RS10515	COG2223	nitrite transmembrane transporter activity
AOZ07_RS10525	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AOZ07_RS10530	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AOZ07_RS10535	COG0508	dehydrogenase complex catalyzes the overall conversion of
AOZ07_RS10550	COG0321	lipoyl(octanoyl) transferase activity
AOZ07_RS10555	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AOZ07_RS10570	COG0174	glutamine synthetase
AOZ07_RS10585	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AOZ07_RS10590	COG0174	glutamine synthetase
AOZ07_RS10595	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AOZ07_RS10610	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AOZ07_RS10615	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AOZ07_RS10620	COG0587	DNA-directed DNA polymerase activity
AOZ07_RS10630	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AOZ07_RS10645	COG1799	cell septum assembly
AOZ07_RS10650	COG1496	oxidoreductase activity
AOZ07_RS10655	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AOZ07_RS10660	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AOZ07_RS10665	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AOZ07_RS10670	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AOZ07_RS10675	COG0772	Belongs to the SEDS family
AOZ07_RS10680	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AOZ07_RS10685	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AOZ07_RS10695	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AOZ07_RS10710	COG0275	rRNA processing
AOZ07_RS10715	COG2001	Belongs to the MraZ family
AOZ07_RS10725	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AOZ07_RS10730	COG0142	geranyltranstransferase activity
AOZ07_RS10740	COG1388	LysM domain
AOZ07_RS10740	COG3942	CHAP domain
AOZ07_RS10750	COG2902	Dehydrogenase
AOZ07_RS10775	COG0653	protein targeting
AOZ07_RS10780	COG3214	Protein conserved in bacteria
AOZ07_RS10785	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AOZ07_RS10795	COG5401	PFAM Sporulation and spore germination
AOZ07_RS10800	COG5002	protein histidine kinase activity
AOZ07_RS10800	COG5000	phosphorelay sensor kinase activity
AOZ07_RS10805	COG0745	RESPONSE REGULATOR receiver
AOZ07_RS10825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOZ07_RS10830	COG0601	transmembrane transport
AOZ07_RS10835	COG4533	DNA binding
AOZ07_RS10845	COG0482	sulfurtransferase activity
AOZ07_RS10860	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AOZ07_RS10875	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AOZ07_RS10890	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AOZ07_RS10900	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AOZ07_RS10910	COG1842	Phage shock protein A
AOZ07_RS10935	COG1615	UPF0182 protein
AOZ07_RS10940	COG3480	Lon protease (S16) C-terminal proteolytic domain
AOZ07_RS10970	COG0210	DNA helicase
AOZ07_RS10990	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AOZ07_RS10995	COG2011	ABC-type metal ion transport system permease component
AOZ07_RS11000	COG1464	Belongs to the NlpA lipoprotein family
AOZ07_RS11005	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AOZ07_RS11010	COG0113	porphobilinogen synthase activity
AOZ07_RS11020	COG0181	hydroxymethylbilane synthase activity
AOZ07_RS11025	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AOZ07_RS11030	COG3253	May function as heme-dependent peroxidase
AOZ07_RS11035	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AOZ07_RS11040	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AOZ07_RS11045	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AOZ07_RS11050	COG1309	transcriptional regulator
AOZ07_RS11060	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
AOZ07_RS11070	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AOZ07_RS11080	COG0006	proline dipeptidase activity
AOZ07_RS11090	COG2239	Acts as a magnesium transporter
AOZ07_RS11100	COG2151	metal-sulfur cluster biosynthetic enzyme
AOZ07_RS11100	COG0489	protein tyrosine kinase activity
AOZ07_RS11105	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AOZ07_RS11130	COG1126	abc transporter atp-binding protein
AOZ07_RS11135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOZ07_RS11140	COG0765	amino acid transport
AOZ07_RS11145	COG0765	amino acid transport
AOZ07_RS11150	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AOZ07_RS11155	COG2171	N-acyltransferase activity
AOZ07_RS11190	COG1217	gtp-binding protein TYPA
AOZ07_RS11205	COG2022	thiamine diphosphate biosynthetic process
AOZ07_RS11220	COG0668	transmembrane transport
AOZ07_RS11235	COG0596	Alpha beta hydrolase
AOZ07_RS11245	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AOZ07_RS11265	COG4335	DNA alkylation repair
AOZ07_RS11270	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AOZ07_RS11285	COG0183	Belongs to the thiolase family
AOZ07_RS11290	COG1960	acyl-CoA dehydrogenase activity
AOZ07_RS11295	COG0823	Involved in the tonB-independent uptake of proteins
AOZ07_RS11360	COG1473	amidohydrolase
AOZ07_RS11385	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
AOZ07_RS11410	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOZ07_RS11415	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AOZ07_RS11525	COG1396	sequence-specific DNA binding
AOZ07_RS11550	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
AOZ07_RS11580	COG0012	GTP binding
AOZ07_RS11585	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AOZ07_RS11595	COG1570	exodeoxyribonuclease VII activity
AOZ07_RS11600	COG1722	exodeoxyribonuclease VII activity
AOZ07_RS11605	COG2326	polyphosphate kinase activity
AOZ07_RS11625	COG1522	sequence-specific DNA binding
AOZ07_RS11640	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AOZ07_RS11660	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AOZ07_RS11660	COG0519	Catalyzes the synthesis of GMP from XMP
AOZ07_RS11675	COG0516	GMP reductase activity
AOZ07_RS11685	COG3226	Transcriptional regulator
AOZ07_RS11690	COG0110	maltose O-acetyltransferase activity
AOZ07_RS11700	COG3246	L-lysine catabolic process to acetate
AOZ07_RS11705	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ07_RS11715	COG1609	Transcriptional regulator
AOZ07_RS11735	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AOZ07_RS11735	COG2755	lipolytic protein G-D-S-L family
AOZ07_RS11740	COG0459	protein refolding
AOZ07_RS11745	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AOZ07_RS11750	COG0833	amino acid
AOZ07_RS11760	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AOZ07_RS11780	COG0477	Major facilitator Superfamily
AOZ07_RS11785	COG2188	Transcriptional regulator
AOZ07_RS11790	COG2807	transmembrane transport
AOZ07_RS11795	COG0179	Fumarylacetoacetate (FAA) hydrolase
AOZ07_RS11800	COG1609	Transcriptional regulator
AOZ07_RS11805	COG1621	beta-fructofuranosidase activity
AOZ07_RS11820	COG1621	beta-fructofuranosidase activity
AOZ07_RS11825	COG1609	Transcriptional regulator
AOZ07_RS11830	COG0395	ABC-type sugar transport system, permease component
AOZ07_RS11835	COG1175	transmembrane transport
AOZ07_RS11850	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AOZ07_RS11855	COG1247	-acetyltransferase
AOZ07_RS11860	COG1214	PFAM Peptidase M22, glycoprotease
AOZ07_RS11860	COG0456	acetyltransferase
AOZ07_RS11865	COG0802	atpase or kinase
AOZ07_RS11870	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AOZ07_RS11875	COG1970	mechanosensitive ion channel activity
AOZ07_RS11880	COG1072	(Pantothenic acid kinase))
AOZ07_RS11885	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AOZ07_RS11890	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AOZ07_RS11895	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AOZ07_RS11905	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AOZ07_RS11905	COG2213	PTS system mannitol-specific
AOZ07_RS11910	COG0246	Mannitol dehydrogenase
AOZ07_RS11915	COG0736	holo-[acyl-carrier-protein] synthase activity
AOZ07_RS11920	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AOZ07_RS11925	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AOZ07_RS11930	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AOZ07_RS11935	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AOZ07_RS11940	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AOZ07_RS11945	COG0101	tRNA pseudouridine synthase activity
AOZ07_RS11960	COG0203	ribosomal protein L17
AOZ07_RS11965	COG0202	RNA polymerase activity
AOZ07_RS11970	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AOZ07_RS11975	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AOZ07_RS11980	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AOZ07_RS11990	COG0563	adenylate kinase activity
AOZ07_RS12000	COG0200	Binds to the 23S rRNA
AOZ07_RS12005	COG1841	ribosomal large subunit assembly
AOZ07_RS12010	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AOZ07_RS12015	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AOZ07_RS12020	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AOZ07_RS12025	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AOZ07_RS12030	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AOZ07_RS12035	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AOZ07_RS12040	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AOZ07_RS12075	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AOZ07_RS12085	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AOZ07_RS12090	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AOZ07_RS12095	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AOZ07_RS12100	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AOZ07_RS12105	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AOZ07_RS12110	COG0089	rRNA binding
AOZ07_RS12115	COG0088	Forms part of the polypeptide exit tunnel
AOZ07_RS12120	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AOZ07_RS12125	COG0051	transcription antitermination factor activity, RNA binding
AOZ07_RS12135	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AOZ07_RS12140	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AOZ07_RS12145	COG0049	tRNA binding
AOZ07_RS12150	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AOZ07_RS12155	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AOZ07_RS12160	COG0085	RNA polymerase activity
AOZ07_RS12175	COG0222	ribosome binding
AOZ07_RS12180	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AOZ07_RS12185	COG0081	regulation of translation
AOZ07_RS12190	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AOZ07_RS12210	COG0436	Aminotransferase
AOZ07_RS12215	COG2197	response regulator
AOZ07_RS12250	COG3485	protocatechuate 3,4-dioxygenase
AOZ07_RS12260	COG0745	RESPONSE REGULATOR receiver
AOZ07_RS12265	COG0456	acetyltransferase
AOZ07_RS12270	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AOZ07_RS12285	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AOZ07_RS12300	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AOZ07_RS12310	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AOZ07_RS12315	COG0738	Major facilitator superfamily
AOZ07_RS12325	COG2030	dehydratase
AOZ07_RS12340	COG1120	ATPase activity
AOZ07_RS12345	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOZ07_RS12350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOZ07_RS12365	COG2357	RelA SpoT domain protein
AOZ07_RS12415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AOZ07_RS12425	COG1666	GTP binding
AOZ07_RS12505	COG0501	Belongs to the peptidase M48B family
AOZ07_RS12520	COG0733	neurotransmitter:sodium symporter activity
AOZ07_RS12540	COG0142	geranyltranstransferase activity
AOZ07_RS12550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOZ07_RS12555	COG0765	amino acid transport
AOZ07_RS12560	COG1126	abc transporter atp-binding protein
AOZ07_RS12565	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AOZ07_RS12575	COG4948	Mandelate Racemase Muconate Lactonizing
AOZ07_RS12590	COG0508	dehydrogenase complex catalyzes the overall conversion of
AOZ07_RS12595	COG0022	dehydrogenase e1 component
AOZ07_RS12605	COG1522	sequence-specific DNA binding
AOZ07_RS12610	COG1024	Enoyl-CoA hydratase
AOZ07_RS12615	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AOZ07_RS12620	COG2151	metal-sulfur cluster biosynthetic enzyme
AOZ07_RS12625	COG3396	Phenylacetate-CoA oxygenase
AOZ07_RS12630	COG3460	Phenylacetate-CoA oxygenase
AOZ07_RS12635	COG3396	Phenylacetate-CoA oxygenase
AOZ07_RS12640	COG2259	Doxx family
AOZ07_RS12650	COG0765	amino acid transport
AOZ07_RS12665	COG2050	protein possibly involved in aromatic compounds catabolism
AOZ07_RS12690	COG1012	belongs to the aldehyde dehydrogenase family
AOZ07_RS12690	COG2030	dehydratase
AOZ07_RS12705	COG1250	3-hydroxyacyl-CoA dehydrogenase
AOZ07_RS12710	COG1024	Enoyl-CoA hydratase
AOZ07_RS12720	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AOZ07_RS12745	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AOZ07_RS12755	COG0785	Cytochrome C biogenesis protein
AOZ07_RS12765	COG0406	alpha-ribazole phosphatase activity
AOZ07_RS12775	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AOZ07_RS12795	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AOZ07_RS12800	COG0640	Transcriptional regulator
AOZ07_RS12805	COG0123	including yeast histone deacetylase and acetoin utilization protein
AOZ07_RS12810	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AOZ07_RS12815	COG0569	domain protein
AOZ07_RS12825	COG1082	Xylose isomerase domain protein TIM barrel
AOZ07_RS12830	COG0248	Ppx GppA phosphatase
AOZ07_RS12835	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AOZ07_RS12835	COG1754	DNA topoisomerase type I activity
AOZ07_RS12845	COG2890	protein-(glutamine-N5) methyltransferase activity
AOZ07_RS12855	COG1054	Belongs to the UPF0176 family
AOZ07_RS12865	COG1111	helicase
AOZ07_RS12865	COG1205	dead DEAH box helicase
AOZ07_RS12905	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AOZ07_RS12905	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AOZ07_RS12915	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AOZ07_RS12920	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AOZ07_RS12925	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AOZ07_RS12950	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AOZ07_RS12960	COG1132	(ABC) transporter
AOZ07_RS12965	COG1132	(ABC) transporter
AOZ07_RS12970	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AOZ07_RS12975	COG0151	Belongs to the GarS family
AOZ07_RS13000	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AOZ07_RS13015	COG0745	RESPONSE REGULATOR receiver
AOZ07_RS13025	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AOZ07_RS13040	COG0542	response to heat
AOZ07_RS13050	COG0456	acetyltransferase
AOZ07_RS13060	COG3304	Inner membrane component domain
AOZ07_RS13065	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AOZ07_RS13085	COG0789	Transcriptional regulator
AOZ07_RS13090	COG0484	heat shock protein binding
AOZ07_RS13095	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AOZ07_RS13100	COG0443	Heat shock 70 kDa protein
AOZ07_RS13130	COG2409	Drug exporters of the RND superfamily
AOZ07_RS13140	COG1280	lysine exporter protein (LysE YggA)
AOZ07_RS13155	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AOZ07_RS13165	COG1122	ATPase activity
AOZ07_RS13170	COG4721	ABC-type cobalt transport system, permease component
AOZ07_RS13180	COG1320	monovalent cation:proton antiporter activity
AOZ07_RS13185	COG2212	antiporter activity
AOZ07_RS13190	COG1863	multisubunit Na H antiporter MnhE subunit
AOZ07_RS13195	COG0651	ATP synthesis coupled electron transport
AOZ07_RS13200	COG1006	Multisubunit Na H antiporter MnhC subunit
AOZ07_RS13205	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AOZ07_RS13205	COG2111	Na H antiporter
AOZ07_RS13215	COG0717	Belongs to the dCTP deaminase family
AOZ07_RS13230	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AOZ07_RS13230	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AOZ07_RS13250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOZ07_RS13255	COG0765	amino acid transport
AOZ07_RS13260	COG1126	abc transporter atp-binding protein
AOZ07_RS13265	COG0433	COG0433 Predicted ATPase
AOZ07_RS13275	COG2814	Major facilitator Superfamily
AOZ07_RS13300	COG2847	Copper chaperone PCu(A)C
AOZ07_RS13315	COG0776	regulation of translation
AOZ07_RS13320	COG0776	regulation of translation
AOZ07_RS13335	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AOZ07_RS13340	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AOZ07_RS13345	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AOZ07_RS13355	COG1177	transmembrane transport
AOZ07_RS13360	COG1176	ABC-type spermidine putrescine transport system, permease component I
AOZ07_RS13365	COG3842	ATPase activity
AOZ07_RS13380	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AOZ07_RS13410	COG0277	FAD linked oxidase domain protein
AOZ07_RS13420	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AOZ07_RS13445	COG3226	Transcriptional regulator
AOZ07_RS13460	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOZ07_RS13490	COG1266	CAAX protease self-immunity
AOZ07_RS13500	COG1902	pentaerythritol trinitrate reductase activity
AOZ07_RS13505	COG2239	Acts as a magnesium transporter
AOZ07_RS13515	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AOZ07_RS13520	COG0509	glycine decarboxylation via glycine cleavage system
AOZ07_RS13525	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AOZ07_RS13530	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AOZ07_RS13530	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AOZ07_RS13540	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AOZ07_RS13545	COG0531	amino acid
AOZ07_RS13550	COG0328	RNA-DNA hybrid ribonuclease activity
AOZ07_RS13560	COG0435	Glutathione S-transferase
AOZ07_RS13570	COG1132	(ABC) transporter
AOZ07_RS13580	COG1120	ATPase activity
AOZ07_RS13585	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOZ07_RS13590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOZ07_RS13595	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOZ07_RS13610	COG0577	efflux transmembrane transporter activity
AOZ07_RS13610	COG1136	(ABC) transporter
AOZ07_RS13650	COG1309	transcriptional regulator
AOZ07_RS13655	COG1960	acyl-CoA dehydrogenase activity
AOZ07_RS13660	COG1643	Atp-dependent helicase
AOZ07_RS13665	COG2267	carboxylic ester hydrolase activity
AOZ07_RS13670	COG0667	Aldo Keto reductase
AOZ07_RS13675	COG1012	belongs to the aldehyde dehydrogenase family
AOZ07_RS13700	COG2197	response regulator
AOZ07_RS13730	COG1506	peptidase
AOZ07_RS13730	COG4946	Tricorn protease homolog
AOZ07_RS13730	COG0823	Involved in the tonB-independent uptake of proteins
AOZ07_RS13740	COG2860	membrane
AOZ07_RS13755	COG0477	Major facilitator Superfamily
AOZ07_RS13760	COG1278	Cold shock
AOZ07_RS13765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOZ07_RS13785	COG0583	DNA-binding transcription factor activity
AOZ07_RS13790	COG1024	Enoyl-CoA hydratase
AOZ07_RS13795	COG0069	glutamate synthase activity
AOZ07_RS13800	COG1132	(ABC) transporter
AOZ07_RS13805	COG4988	ABC transporter
AOZ07_RS13815	COG0135	phosphoribosylanthranilate isomerase activity
AOZ07_RS13825	COG4585	Histidine kinase
AOZ07_RS13830	COG2197	response regulator
AOZ07_RS13835	COG4152	abc transporter atp-binding protein
AOZ07_RS13850	COG1012	belongs to the aldehyde dehydrogenase family
AOZ07_RS13855	COG0583	DNA-binding transcription factor activity
AOZ07_RS13860	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AOZ07_RS13865	COG1090	epimerase
AOZ07_RS13890	COG0154	amidase activity
AOZ07_RS13910	COG0561	phosphatase activity
AOZ07_RS13970	COG0604	alcohol dehydrogenase
AOZ07_RS13970	COG3321	synthase
AOZ07_RS14035	COG2814	Major facilitator Superfamily
AOZ07_RS14070	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AOZ07_RS14080	COG0783	Belongs to the Dps family
AOZ07_RS14095	COG2986	histidine ammonia-lyase
AOZ07_RS14100	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AOZ07_RS14120	COG1621	beta-fructofuranosidase activity
AOZ07_RS14160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AOZ07_RS14165	COG1879	ABC-type sugar transport system periplasmic component
AOZ07_RS14170	COG1172	Belongs to the binding-protein-dependent transport system permease family
AOZ07_RS14175	COG1129	ABC transporter
AOZ07_RS14180	COG1609	Transcriptional regulator
AOZ07_RS14185	COG1321	iron dependent repressor
AOZ07_RS14195	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AOZ07_RS14200	COG1121	(ABC) transporter
AOZ07_RS14210	COG0010	Belongs to the arginase family
AOZ07_RS14225	COG0789	Transcriptional regulator
AOZ07_RS14245	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AOZ07_RS14290	COG1522	sequence-specific DNA binding
AOZ07_RS14300	COG2211	Major facilitator Superfamily
AOZ07_RS14305	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AOZ07_RS14310	COG2146	nitrite reductase [NAD(P)H] activity
AOZ07_RS14315	COG2971	BadF BadG BcrA BcrD
AOZ07_RS14325	COG4608	Belongs to the ABC transporter superfamily
AOZ07_RS14330	COG0444	Belongs to the ABC transporter superfamily
AOZ07_RS14335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOZ07_RS14340	COG0601	transmembrane transport
AOZ07_RS14345	COG0747	negative chemotaxis
AOZ07_RS14350	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AOZ07_RS14355	COG0579	oxidoreductase
AOZ07_RS14360	COG2186	Transcriptional regulator
AOZ07_RS14375	COG4221	oxidoreductase activity
AOZ07_RS14380	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ07_RS14385	COG1309	transcriptional regulator
AOZ07_RS14390	COG2610	gluconate transmembrane transporter activity
AOZ07_RS14395	COG0589	response to stress
AOZ07_RS14415	COG0583	DNA-binding transcription factor activity
AOZ07_RS14420	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AOZ07_RS14430	COG4948	Mandelate Racemase Muconate Lactonizing
AOZ07_RS14445	COG0583	DNA-binding transcription factor activity
AOZ07_RS14450	COG4948	Mandelate Racemase Muconate Lactonizing
AOZ07_RS14455	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AOZ07_RS14475	COG1063	alcohol dehydrogenase
AOZ07_RS14480	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ07_RS14485	COG2188	Transcriptional regulator
AOZ07_RS14490	COG1620	l-lactate permease
AOZ07_RS14495	COG0247	lactate metabolic process
AOZ07_RS14500	COG1139	Iron-sulfur cluster binding protein
AOZ07_RS14505	COG1556	Lactate utilization protein
AOZ07_RS14540	COG1732	Glycine betaine
AOZ07_RS14545	COG1174	glycine betaine transport
AOZ07_RS14555	COG1174	glycine betaine transport
AOZ07_RS14560	COG0179	Fumarylacetoacetate (FAA) hydrolase
AOZ07_RS14575	COG1115	amino acid carrier protein
AOZ07_RS14580	COG2301	Belongs to the HpcH HpaI aldolase family
AOZ07_RS14585	COG1113	amino acid transport
AOZ07_RS14615	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOZ07_RS14620	COG1414	Transcriptional regulator
AOZ07_RS14630	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AOZ07_RS14645	COG2855	membrane
AOZ07_RS14650	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ07_RS14685	COG1960	acyl-CoA dehydrogenase activity
AOZ07_RS14700	COG1473	amidohydrolase
AOZ07_RS14705	COG0477	Major facilitator Superfamily
AOZ07_RS14710	COG1733	regulation of RNA biosynthetic process
AOZ07_RS14730	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOZ07_RS14780	COG0183	Belongs to the thiolase family
AOZ07_RS14785	COG0406	alpha-ribazole phosphatase activity
AOZ07_RS14790	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AOZ07_RS14795	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AOZ07_RS14800	COG0640	Transcriptional regulator
AOZ07_RS14815	COG2186	Transcriptional regulator
AOZ07_RS14825	COG1850	ribulose-bisphosphate carboxylase activity
AOZ07_RS14840	COG2186	Transcriptional regulator
AOZ07_RS14850	COG1027	Aspartate ammonia-lyase
AOZ07_RS14870	COG0823	Involved in the tonB-independent uptake of proteins
AOZ07_RS14870	COG1506	peptidase
AOZ07_RS14895	COG0508	dehydrogenase complex catalyzes the overall conversion of
AOZ07_RS14900	COG0022	dehydrogenase e1 component
AOZ07_RS14910	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AOZ07_RS14915	COG1950	PFAM Membrane protein of
AOZ07_RS14930	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AOZ07_RS14990	COG2197	response regulator
AOZ07_RS15000	COG0833	amino acid
AOZ07_RS15015	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AOZ07_RS15025	COG2252	PERMEase
AOZ07_RS15030	COG0590	tRNA wobble adenosine to inosine editing
AOZ07_RS15035	COG2223	nitrite transmembrane transporter activity
AOZ07_RS15040	COG0243	molybdopterin cofactor binding
AOZ07_RS15045	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AOZ07_RS15055	COG2146	nitrite reductase [NAD(P)H] activity
AOZ07_RS15055	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AOZ07_RS15075	COG2233	PERMEase
AOZ07_RS15085	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AOZ07_RS15090	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AOZ07_RS15100	COG1802	Transcriptional regulator
AOZ07_RS15115	COG0596	Alpha beta hydrolase
AOZ07_RS15120	COG1012	belongs to the aldehyde dehydrogenase family
AOZ07_RS15125	COG1942	4-Oxalocrotonate Tautomerase
AOZ07_RS15130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOZ07_RS15145	COG0318	PFAM AMP-dependent synthetase and ligase
AOZ07_RS15160	COG1172	Belongs to the binding-protein-dependent transport system permease family
AOZ07_RS15165	COG1172	Belongs to the binding-protein-dependent transport system permease family
AOZ07_RS15175	COG1879	ABC-type sugar transport system periplasmic component
AOZ07_RS15185	COG2197	response regulator
AOZ07_RS15190	COG4585	Histidine kinase
AOZ07_RS15200	COG1131	(ABC) transporter
AOZ07_RS15215	COG0436	Aminotransferase
AOZ07_RS15220	COG3949	Membrane
AOZ07_RS15230	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AOZ07_RS15235	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AOZ07_RS15265	COG2957	Belongs to the agmatine deiminase family
AOZ07_RS15310	COG2066	Belongs to the glutaminase family
AOZ07_RS15315	COG1607	acyl-coa hydrolase
AOZ07_RS15330	COG0473	3-isopropylmalate dehydrogenase activity
AOZ07_RS15335	COG1802	Transcriptional regulator
AOZ07_RS15340	COG1012	belongs to the aldehyde dehydrogenase family
AOZ07_RS15345	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ07_RS15350	COG2186	Transcriptional regulator
AOZ07_RS15355	COG0154	amidase activity
AOZ07_RS15365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOZ07_RS15380	COG2186	Transcriptional regulator
AOZ07_RS15420	COG1129	ABC transporter
AOZ07_RS15450	COG3177	Filamentation induced by cAMP protein fic
AOZ07_RS15475	COG1937	Protein conserved in bacteria
AOZ07_RS15520	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AOZ07_RS15525	COG0531	amino acid
AOZ07_RS15540	COG1012	belongs to the aldehyde dehydrogenase family
AOZ07_RS15565	COG2072	flavoprotein involved in K transport
AOZ07_RS15610	COG4592	Periplasmic binding protein
AOZ07_RS15615	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOZ07_RS15620	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOZ07_RS15635	COG0534	Mate efflux family protein
AOZ07_RS15645	COG2814	Major facilitator Superfamily
AOZ07_RS15650	COG1266	CAAX protease self-immunity
AOZ07_RS15665	COG0583	DNA-binding transcription factor activity
AOZ07_RS15700	COG2154	pterin-4-alpha-carbinolamine dehydratase
AOZ07_RS15740	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ07_RS15755	COG1012	belongs to the aldehyde dehydrogenase family
AOZ07_RS15775	COG0640	Transcriptional regulator
AOZ07_RS15790	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AOZ07_RS15795	COG3285	dna ligase
AOZ07_RS15795	COG1793	dna ligase
AOZ07_RS15810	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AOZ07_RS15830	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AOZ07_RS15835	COG0531	amino acid
AOZ07_RS15855	COG0747	negative chemotaxis
AOZ07_RS15865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOZ07_RS15870	COG4172	Belongs to the ABC transporter superfamily
AOZ07_RS15890	COG1902	pentaerythritol trinitrate reductase activity
AOZ07_RS15895	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ07_RS15900	COG1122	ATPase activity
AOZ07_RS15915	COG1957	nucleoside hydrolase
AOZ07_RS15925	COG0494	nUDIX hydrolase
AOZ07_RS15930	COG2271	Major facilitator Superfamily
AOZ07_RS15935	COG4948	Mandelate Racemase Muconate Lactonizing
AOZ07_RS15940	COG0800	Aldolase
AOZ07_RS15945	COG3734	2-keto-3-deoxy-galactonokinase
AOZ07_RS15950	COG1414	Transcriptional regulator
AOZ07_RS15955	COG2186	Transcriptional regulator
AOZ07_RS15960	COG0531	amino acid
AOZ07_RS15970	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AOZ07_RS15975	COG1012	belongs to the aldehyde dehydrogenase family
AOZ07_RS15995	COG3639	organic phosphonate transmembrane transporter activity
AOZ07_RS16000	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AOZ07_RS16010	COG0666	response to abiotic stimulus
AOZ07_RS16015	COG4585	Histidine kinase
AOZ07_RS16020	COG2197	response regulator
AOZ07_RS16040	COG0673	inositol 2-dehydrogenase activity
AOZ07_RS16055	COG1609	Transcriptional regulator
AOZ07_RS16065	COG0800	Aldolase
AOZ07_RS16095	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AOZ07_RS16100	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOZ07_RS16105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOZ07_RS16110	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AOZ07_RS16130	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AOZ07_RS16165	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
AOZ07_RS16170	COG1136	(ABC) transporter
AOZ07_RS16180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOZ07_RS16190	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AOZ07_RS16225	COG2814	Major facilitator Superfamily
AOZ07_RS16230	COG3250	beta-galactosidase activity
AOZ07_RS16260	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AOZ07_RS16275	COG1309	transcriptional regulator
AOZ07_RS16280	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AOZ07_RS16295	COG1309	transcriptional regulator
AOZ07_RS16300	COG3250	beta-galactosidase activity
AOZ07_RS16305	COG1113	amino acid transport
AOZ07_RS16320	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AOZ07_RS16325	COG0798	PFAM Bile acid sodium symporter
AOZ07_RS16345	COG0659	secondary active sulfate transmembrane transporter activity
AOZ07_RS16360	COG1073	alpha beta
AOZ07_RS16405	COG2084	Dehydrogenase
AOZ07_RS16410	COG2610	gluconate transmembrane transporter activity
AOZ07_RS16425	COG1280	lysine exporter protein (LysE YggA)
AOZ07_RS16445	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AOZ07_RS16450	COG1063	alcohol dehydrogenase
AOZ07_RS16455	COG0583	DNA-binding transcription factor activity
AOZ07_RS16475	COG2261	transglycosylase associated protein
AOZ07_RS16500	COG1192	Involved in chromosome partitioning
AOZ07_RS16525	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AOZ07_RS16530	COG0436	Aminotransferase
AOZ07_RS16540	COG0415	Belongs to the DNA photolyase family
AOZ07_RS16545	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AOZ07_RS16550	COG3404	Formiminotransferase-cyclodeaminase
AOZ07_RS16555	COG0583	DNA-binding transcription factor activity
AOZ07_RS16570	COG0589	response to stress
AOZ07_RS16575	COG1846	Transcriptional regulator
AOZ07_RS16600	COG3960	tartronate-semialdehyde synthase activity
AOZ07_RS16605	COG2084	Dehydrogenase
AOZ07_RS16610	COG3622	Belongs to the hyi family
AOZ07_RS16615	COG1953	Uracil, thiamine, allantoin
AOZ07_RS16630	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AOZ07_RS16635	COG0473	3-isopropylmalate dehydrogenase activity
AOZ07_RS16640	COG3619	membrane
AOZ07_RS16705	COG0583	DNA-binding transcription factor activity
AOZ07_RS16710	COG1280	lysine exporter protein (LysE YggA)
AOZ07_RS16720	COG2837	iron assimilation
AOZ07_RS16735	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ07_RS16750	COG0667	Aldo Keto reductase
AOZ07_RS16760	COG0444	Belongs to the ABC transporter superfamily
AOZ07_RS16765	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOZ07_RS16770	COG0601	transmembrane transport
AOZ07_RS16775	COG0747	negative chemotaxis
AOZ07_RS16780	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AOZ07_RS16795	COG2828	Protein conserved in bacteria
AOZ07_RS16825	COG1302	Protein conserved in bacteria
AOZ07_RS16830	COG4941	Belongs to the sigma-70 factor family
AOZ07_RS16850	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AOZ07_RS16875	COG2207	Transcriptional regulator
AOZ07_RS16880	COG1120	ATPase activity
AOZ07_RS16900	COG1940	carbohydrate kinase activity
AOZ07_RS16910	COG1175	transmembrane transport
AOZ07_RS16915	COG0395	ABC-type sugar transport system, permease component
AOZ07_RS16920	COG0366	Alpha amylase catalytic
AOZ07_RS16955	COG2149	membrane
AOZ07_RS16965	COG0477	Major facilitator Superfamily
AOZ07_RS16990	COG1172	Belongs to the binding-protein-dependent transport system permease family
AOZ07_RS16995	COG1172	Belongs to the binding-protein-dependent transport system permease family
AOZ07_RS17000	COG1129	ABC transporter
AOZ07_RS17005	COG1879	ABC-type sugar transport system periplasmic component
AOZ07_RS17015	COG2610	gluconate transmembrane transporter activity
AOZ07_RS17035	COG1929	Belongs to the glycerate kinase type-1 family
AOZ07_RS17040	COG0659	secondary active sulfate transmembrane transporter activity
AOZ07_RS17045	COG0456	acetyltransferase
AOZ07_RS17050	COG2199	diguanylate cyclase activity
AOZ07_RS17065	COG0463	Glycosyl transferase, family 2
AOZ07_RS17070	COG0318	PFAM AMP-dependent synthetase and ligase
AOZ07_RS17120	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AOZ07_RS17130	COG2813	Specifically methylates the guanine in position
AOZ07_RS17140	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ07_RS17140	COG3347	Dehydrogenase
AOZ07_RS17145	COG2814	Major facilitator Superfamily
AOZ07_RS17190	COG3257	ureidoglycine aminohydrolase activity
AOZ07_RS17200	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AOZ07_RS17205	COG1414	Transcriptional regulator
AOZ07_RS17210	COG2814	Major facilitator Superfamily
AOZ07_RS17220	COG1132	(ABC) transporter
AOZ07_RS17225	COG1301	dicarboxylic acid transport
AOZ07_RS17230	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ07_RS17245	COG0667	Aldo Keto reductase
AOZ07_RS17250	COG0673	inositol 2-dehydrogenase activity
AOZ07_RS17255	COG2814	Major facilitator Superfamily
AOZ07_RS17265	COG0667	Aldo Keto reductase
AOZ07_RS17280	COG0673	inositol 2-dehydrogenase activity
AOZ07_RS17290	COG0673	inositol 2-dehydrogenase activity
AOZ07_RS17315	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AOZ07_RS17325	COG2017	converts alpha-aldose to the beta-anomer
AOZ07_RS17330	COG4214	carbohydrate transport
AOZ07_RS17340	COG4213	ABC transporter substrate-binding protein
AOZ07_RS17345	COG2160	L-arabinose isomerase activity
AOZ07_RS17360	COG1609	Transcriptional regulator
AOZ07_RS17365	COG2814	Major facilitator Superfamily
AOZ07_RS17375	COG0673	inositol 2-dehydrogenase activity
AOZ07_RS17380	COG1129	ABC transporter
AOZ07_RS17385	COG1172	Belongs to the binding-protein-dependent transport system permease family
AOZ07_RS17395	COG1609	Transcriptional regulator
AOZ07_RS17400	COG0673	inositol 2-dehydrogenase activity
AOZ07_RS17405	COG2188	Transcriptional regulator
AOZ07_RS17410	COG3718	enzyme involved in inositol metabolism
AOZ07_RS17420	COG0673	inositol 2-dehydrogenase activity
AOZ07_RS17425	COG1609	Transcriptional regulator
AOZ07_RS17430	COG2814	Major facilitator Superfamily
AOZ07_RS17435	COG1082	Xylose isomerase domain protein TIM barrel
AOZ07_RS17440	COG1082	Xylose isomerase domain protein TIM barrel
AOZ07_RS17445	COG0673	inositol 2-dehydrogenase activity
AOZ07_RS17450	COG1082	Xylose isomerase domain protein TIM barrel
AOZ07_RS17460	COG3962	Belongs to the TPP enzyme family
AOZ07_RS17470	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AOZ07_RS17475	COG1609	Transcriptional regulator
AOZ07_RS17490	COG0778	Nitroreductase
AOZ07_RS17495	COG2814	Major facilitator Superfamily
AOZ07_RS17530	COG0601	transmembrane transport
AOZ07_RS17535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOZ07_RS17540	COG4172	Belongs to the ABC transporter superfamily
AOZ07_RS17555	COG2971	BadF BadG BcrA BcrD
AOZ07_RS17560	COG1940	carbohydrate kinase activity
AOZ07_RS17575	COG4209	transmembrane transport
AOZ07_RS17580	COG0395	ABC-type sugar transport system, permease component
AOZ07_RS17585	COG1653	transport
AOZ07_RS17600	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AOZ07_RS17605	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AOZ07_RS17615	COG1349	DNA-binding transcription factor activity
AOZ07_RS17625	COG1175	transmembrane transport
AOZ07_RS17630	COG0395	ABC-type sugar transport system, permease component
AOZ07_RS17640	COG2233	PERMEase
AOZ07_RS17650	COG2351	hydroxyisourate hydrolase activity
AOZ07_RS17670	COG4221	oxidoreductase activity
AOZ07_RS17690	COG1846	Transcriptional regulator
AOZ07_RS17750	COG0305	Participates in initiation and elongation during chromosome replication
AOZ07_RS17755	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AOZ07_RS17790	COG0359	binds to the 23S rRNA
AOZ07_RS17795	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AOZ07_RS17805	COG0360	Binds together with S18 to 16S ribosomal RNA
AOZ07_RS17810	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AOZ07_RS17810	COG2755	lipolytic protein G-D-S-L family
AOZ07_RS17825	COG1362	aminopeptidase activity
AOZ07_RS17830	COG5416	Lipopolysaccharide assembly protein A domain
AOZ07_RS17835	COG2197	response regulator
AOZ07_RS17840	COG4585	Histidine kinase
AOZ07_RS17875	COG2089	acid synthase
AOZ07_RS17880	COG1442	glycosyl transferase family 8
AOZ07_RS17880	COG1216	Glycosyl transferase, family 2
AOZ07_RS17900	COG1260	myo-inositol-1-phosphate synthase
AOZ07_RS17905	COG0617	tRNA 3'-terminal CCA addition
AOZ07_RS17915	COG0728	peptidoglycan biosynthetic process
AOZ07_RS17925	COG0492	ferredoxin-NADP+ reductase activity
AOZ07_RS17930	COG3118	belongs to the thioredoxin family
AOZ07_RS17940	COG1475	DNA binding
AOZ07_RS17945	COG1192	Involved in chromosome partitioning
AOZ07_RS17950	COG0357	Ribosomal RNA small subunit methyltransferase G
AOZ07_RS17955	COG1847	R3H domain protein
AOZ07_RS17960	COG0706	membrane insertase activity
AOZ07_RS18025	COG0010	Belongs to the arginase family
AOZ07_RS18135	COG1876	peptidase activity
AOZ07_RS18145	COG0739	heme binding
AOZ07_RS18145	COG1196	nuclear chromosome segregation
AOZ07_RS18145	COG0741	lytic transglycosylase activity
AOZ07_RS18190	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AOZ07_RS18205	COG0515	serine threonine protein kinase
AOZ07_RS18205	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AOZ07_RS18225	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOZ07_RS18225	COG2022	thiamine diphosphate biosynthetic process
AOZ07_RS18250	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AOZ07_RS18305	COG2610	gluconate transmembrane transporter activity
AOZ07_RS18350	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AOZ07_RS18355	COG0594	ribonuclease P activity
AOZ07_RS18360	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AOZ07_RS18380	COG0477	Major facilitator Superfamily
AOZ07_RS18385	COG0477	Major facilitator Superfamily
AOZ07_RS18450	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AOZ07_RS18520	COG0739	heme binding