locus-tag	class	description
F0M17_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
F0M17_RS00010	COG0592	DNA-directed DNA polymerase activity
F0M17_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
F0M17_RS00020	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
F0M17_RS00025	COG0187	DNA topoisomerase II activity
F0M17_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
F0M17_RS00035	COG3266	domain, Protein
F0M17_RS00060	COG0385	Bile acid
F0M17_RS00090	COG0583	DNA-binding transcription factor activity
F0M17_RS00095	COG2076	Multidrug Resistance protein
F0M17_RS00105	COG3764	Sortase (surface protein transpeptidase)
F0M17_RS00115	COG0515	serine threonine protein kinase
F0M17_RS00115	COG2815	serine threonine protein kinase
F0M17_RS00120	COG0515	serine threonine protein kinase
F0M17_RS00125	COG0768	penicillin binding
F0M17_RS00140	COG1716	ATPase activity
F0M17_RS00155	COG1683	Conserved Protein
F0M17_RS00170	COG1609	Transcriptional regulator
F0M17_RS00175	COG1957	nucleoside hydrolase
F0M17_RS00180	COG0412	Dienelactone hydrolase
F0M17_RS00195	COG1024	Enoyl-CoA hydratase
F0M17_RS00210	COG0561	phosphatase activity
F0M17_RS00230	COG0477	Major facilitator Superfamily
F0M17_RS00235	COG2233	PERMEase
F0M17_RS00240	COG0352	thiamine-phosphate diphosphorylase activity
F0M17_RS00240	COG0351	phosphomethylpyrimidine kinase
F0M17_RS00240	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
F0M17_RS00245	COG0352	thiamine-phosphate diphosphorylase activity
F0M17_RS00250	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
F0M17_RS00265	COG1012	belongs to the aldehyde dehydrogenase family
F0M17_RS00270	COG0833	amino acid
F0M17_RS00275	COG0033	Phosphoglucomutase
F0M17_RS00285	COG3104	oligopeptide transport
F0M17_RS00290	COG0154	amidase activity
F0M17_RS00300	COG0077	Prephenate dehydratase
F0M17_RS00310	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
F0M17_RS00315	COG0561	phosphatase activity
F0M17_RS00325	COG0515	serine threonine protein kinase
F0M17_RS00345	COG2364	Membrane
F0M17_RS00360	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
F0M17_RS00365	COG2027	D-alanyl-D-alanine carboxypeptidase
F0M17_RS00375	COG0037	tRNA processing
F0M17_RS00385	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
F0M17_RS00390	COG0302	gtp cyclohydrolase
F0M17_RS00400	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
F0M17_RS00425	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
F0M17_RS00450	COG1476	TRANSCRIPTIONal
F0M17_RS00485	COG3590	peptidase
F0M17_RS00490	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
F0M17_RS00520	COG4977	sequence-specific DNA binding
F0M17_RS00530	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
F0M17_RS00550	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
F0M17_RS00555	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
F0M17_RS00580	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
F0M17_RS00590	COG1395	domain, Protein
F0M17_RS00595	COG0306	phosphate transporter
F0M17_RS00630	COG0488	(ABC) transporter
F0M17_RS00645	COG2226	methyltransferase
F0M17_RS00665	COG0583	DNA-binding transcription factor activity
F0M17_RS00700	COG1937	Protein conserved in bacteria
F0M17_RS00705	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F0M17_RS00720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F0M17_RS00735	COG0277	FAD linked oxidase domain protein
F0M17_RS00745	COG0531	amino acid
F0M17_RS00760	COG0589	response to stress
F0M17_RS00770	COG1802	Transcriptional regulator
F0M17_RS00785	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
F0M17_RS00805	COG3265	gluconokinase activity
F0M17_RS00870	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
F0M17_RS00890	COG4122	O-methyltransferase activity
F0M17_RS00915	COG2252	PERMEase
F0M17_RS00930	COG2801	Transposase and inactivated derivatives
F0M17_RS00970	COG1024	Enoyl-CoA hydratase
F0M17_RS00985	COG1960	acyl-CoA dehydrogenase activity
F0M17_RS01005	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
F0M17_RS01015	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
F0M17_RS01020	COG1609	Transcriptional regulator
F0M17_RS01030	COG1175	transmembrane transport
F0M17_RS01040	COG1472	Belongs to the glycosyl hydrolase 3 family
F0M17_RS01065	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F0M17_RS01065	COG0357	Ribosomal RNA small subunit methyltransferase G
F0M17_RS01070	COG1196	nuclear chromosome segregation
F0M17_RS01070	COG0739	heme binding
F0M17_RS01070	COG0741	lytic transglycosylase activity
F0M17_RS01095	COG0745	RESPONSE REGULATOR receiver
F0M17_RS01100	COG5002	protein histidine kinase activity
F0M17_RS01125	COG1435	thymidine kinase activity
F0M17_RS01135	COG1070	Carbohydrate kinase
F0M17_RS01145	COG1940	carbohydrate kinase activity
F0M17_RS01155	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
F0M17_RS01165	COG0028	Belongs to the TPP enzyme family
F0M17_RS01205	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
F0M17_RS01210	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F0M17_RS01210	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F0M17_RS01210	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F0M17_RS01220	COG1349	DNA-binding transcription factor activity
F0M17_RS01225	COG1832	CoA-binding protein
F0M17_RS01230	COG2873	o-acetylhomoserine
F0M17_RS01235	COG0406	alpha-ribazole phosphatase activity
F0M17_RS01245	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F0M17_RS01250	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
F0M17_RS01260	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
F0M17_RS01265	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F0M17_RS01270	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F0M17_RS01295	COG0405	Gamma-glutamyltransferase
F0M17_RS01300	COG0702	epimerase
F0M17_RS01305	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
F0M17_RS01310	COG2011	ABC-type metal ion transport system permease component
F0M17_RS01315	COG1464	Belongs to the NlpA lipoprotein family
F0M17_RS01320	COG0747	negative chemotaxis
F0M17_RS01325	COG0601	transmembrane transport
F0M17_RS01330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F0M17_RS01340	COG1960	acyl-CoA dehydrogenase activity
F0M17_RS01350	COG1832	CoA-binding protein
F0M17_RS01355	COG2315	Protein conserved in bacteria
F0M17_RS01365	COG0737	Belongs to the 5'-nucleotidase family
F0M17_RS01380	COG4592	Periplasmic binding protein
F0M17_RS01390	COG2824	Alkylphosphonate utilization operon protein PhnA
F0M17_RS01395	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F0M17_RS01405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F0M17_RS01415	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
F0M17_RS01420	COG0047	phosphoribosylformylglycinamidine synthase activity
F0M17_RS01425	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
F0M17_RS01430	COG3012	SEC-C Motif Domain Protein
F0M17_RS01460	COG2318	DinB family
F0M17_RS01470	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
F0M17_RS01480	COG1316	TRANSCRIPTIONal
F0M17_RS01490	COG2851	Citrate transporter
F0M17_RS01495	COG3290	protein histidine kinase activity
F0M17_RS01500	COG4565	transcriptional regulatory protein
F0M17_RS01530	COG1846	Transcriptional regulator
F0M17_RS01540	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
F0M17_RS01550	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
F0M17_RS01605	COG0406	alpha-ribazole phosphatase activity
F0M17_RS01625	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
F0M17_RS01675	COG0542	response to heat
F0M17_RS01680	COG2197	response regulator
F0M17_RS01690	COG0778	Nitroreductase
F0M17_RS01725	COG1472	Belongs to the glycosyl hydrolase 3 family
F0M17_RS01730	COG1404	Belongs to the peptidase S8 family
F0M17_RS01740	COG0351	phosphomethylpyrimidine kinase
F0M17_RS01750	COG1309	transcriptional regulator
F0M17_RS01760	COG1120	ATPase activity
F0M17_RS01775	COG0343	queuine tRNA-ribosyltransferase activity
F0M17_RS01790	COG2814	Major facilitator Superfamily
F0M17_RS01805	COG0564	pseudouridine synthase activity
F0M17_RS01810	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
F0M17_RS01820	COG1201	RNA secondary structure unwinding
F0M17_RS01835	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
F0M17_RS01840	COG0671	phosphoesterase, PA-phosphatase related
F0M17_RS01845	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F0M17_RS01860	COG0824	Thioesterase
F0M17_RS01875	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
F0M17_RS01880	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F0M17_RS01895	COG3485	protocatechuate 3,4-dioxygenase
F0M17_RS01900	COG3485	protocatechuate 3,4-dioxygenase
F0M17_RS01915	COG1028	Short-chain dehydrogenase reductase Sdr
F0M17_RS01925	COG1960	acyl-CoA dehydrogenase activity
F0M17_RS01945	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F0M17_RS01950	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F0M17_RS01955	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F0M17_RS01960	COG1116	anion transmembrane transporter activity
F0M17_RS01975	COG0543	2 iron, 2 sulfur cluster binding
F0M17_RS01975	COG0633	Ferredoxin
F0M17_RS01980	COG2814	Major facilitator Superfamily
F0M17_RS01990	COG0477	Major facilitator Superfamily
F0M17_RS01995	COG1234	tRNA 3'-trailer cleavage
F0M17_RS02010	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
F0M17_RS02020	COG2814	Major facilitator Superfamily
F0M17_RS02025	COG0183	Belongs to the thiolase family
F0M17_RS02035	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
F0M17_RS02040	COG1414	Transcriptional regulator
F0M17_RS02090	COG0315	cyclic pyranopterin monophosphate synthase activity
F0M17_RS02090	COG0521	Mo-molybdopterin cofactor biosynthetic process
F0M17_RS02095	COG0315	cyclic pyranopterin monophosphate synthase activity
F0M17_RS02120	COG1349	DNA-binding transcription factor activity
F0M17_RS02125	COG2318	DinB family
F0M17_RS02130	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
F0M17_RS02155	COG0746	molybdenum cofactor guanylyltransferase activity
F0M17_RS02170	COG1140	nitrate reductase beta subunit
F0M17_RS02195	COG0584	glycerophosphoryl diester phosphodiesterase
F0M17_RS02410	COG0739	heme binding
F0M17_RS02435	COG0438	transferase activity, transferring glycosyl groups
F0M17_RS02485	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
F0M17_RS02490	COG2205	protein histidine kinase activity
F0M17_RS02495	COG0745	RESPONSE REGULATOR receiver
F0M17_RS02515	COG1132	(ABC) transporter
F0M17_RS02520	COG1309	transcriptional regulator
F0M17_RS02525	COG1511	domain protein
F0M17_RS02555	COG2723	6-phospho-beta-galactosidase activity
F0M17_RS02575	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F0M17_RS02585	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
F0M17_RS02595	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
F0M17_RS02595	COG0596	Alpha beta hydrolase
F0M17_RS02600	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F0M17_RS02600	COG1017	nitric oxide dioxygenase activity
F0M17_RS02605	COG1959	2 iron, 2 sulfur cluster binding
F0M17_RS02620	COG0514	ATP-dependent DNA helicase (RecQ)
F0M17_RS02635	COG1505	serine-type exopeptidase activity
F0M17_RS02650	COG3321	synthase
F0M17_RS02650	COG0604	alcohol dehydrogenase
F0M17_RS02650	COG1028	Short-chain dehydrogenase reductase Sdr
F0M17_RS02655	COG1966	Carbon starvation protein
F0M17_RS02670	COG0656	L-ascorbic acid biosynthetic process
F0M17_RS02685	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
F0M17_RS02690	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
F0M17_RS02695	COG0626	cystathionine gamma-synthase activity
F0M17_RS02705	COG0588	phosphoglycerate mutase activity
F0M17_RS02720	COG5002	protein histidine kinase activity
F0M17_RS02740	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
F0M17_RS02740	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
F0M17_RS02745	COG0215	cysteine-tRNA ligase activity
F0M17_RS02775	COG0277	FAD linked oxidase domain protein
F0M17_RS02810	COG1028	Short-chain dehydrogenase reductase Sdr
F0M17_RS02820	COG3842	ATPase activity
F0M17_RS02845	COG2354	Protein conserved in bacteria
F0M17_RS02880	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
F0M17_RS02895	COG0459	protein refolding
F0M17_RS02910	COG2205	protein histidine kinase activity
F0M17_RS02915	COG0745	RESPONSE REGULATOR receiver
F0M17_RS02925	COG1278	Cold shock
F0M17_RS02945	COG0739	heme binding
F0M17_RS02960	COG0494	nUDIX hydrolase
F0M17_RS02985	COG0045	succinate-CoA ligase (ADP-forming) activity
F0M17_RS02995	COG0477	Major facilitator Superfamily
F0M17_RS03005	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
F0M17_RS03030	COG1396	sequence-specific DNA binding
F0M17_RS03040	COG0531	amino acid
F0M17_RS03060	COG0028	Belongs to the TPP enzyme family
F0M17_RS03075	COG1846	Transcriptional regulator
F0M17_RS03080	COG0477	Major facilitator Superfamily
F0M17_RS03085	COG1802	Transcriptional regulator
F0M17_RS03105	COG1250	3-hydroxyacyl-CoA dehydrogenase
F0M17_RS03135	COG2818	Glycosylase
F0M17_RS03150	COG1136	(ABC) transporter
F0M17_RS03150	COG0577	efflux transmembrane transporter activity
F0M17_RS03155	COG0577	efflux transmembrane transporter activity
F0M17_RS03155	COG1136	(ABC) transporter
F0M17_RS03200	COG1295	ribonuclease BN
F0M17_RS03210	COG1804	L-carnitine dehydratase bile acid-inducible protein F
F0M17_RS03220	COG3483	tryptophan 2,3-dioxygenase activity
F0M17_RS03225	COG0431	NADPH-dependent FMN reductase
F0M17_RS03230	COG3971	2-oxopent-4-enoate hydratase activity
F0M17_RS03295	COG0477	Major facilitator Superfamily
F0M17_RS03305	COG0138	bifunctional purine biosynthesis protein purh
F0M17_RS03320	COG1914	H( )-stimulated, divalent metal cation uptake system
F0M17_RS03325	COG4336	lyase activity
F0M17_RS03330	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
F0M17_RS03340	COG4770	biotin carboxylase activity
F0M17_RS03345	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
F0M17_RS03350	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
F0M17_RS03360	COG2759	Belongs to the formate--tetrahydrofolate ligase family
F0M17_RS03370	COG2838	Isocitrate dehydrogenase
F0M17_RS03385	COG0232	Belongs to the dGTPase family. Type 2 subfamily
F0M17_RS03430	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
F0M17_RS03545	COG2963	transposase activity
F0M17_RS03550	COG2801	Transposase and inactivated derivatives
F0M17_RS03615	COG0789	Transcriptional regulator
F0M17_RS03645	COG2072	flavoprotein involved in K transport
F0M17_RS03650	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
F0M17_RS03655	COG0477	Major facilitator Superfamily
F0M17_RS03670	COG2197	response regulator
F0M17_RS03690	COG0708	Exodeoxyribonuclease III
F0M17_RS03695	COG0180	Tryptophanyl-tRNA synthetase
F0M17_RS03710	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
F0M17_RS03725	COG2009	succinate dehydrogenase
F0M17_RS03730	COG0662	Cupin 2, conserved barrel domain protein
F0M17_RS03730	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
F0M17_RS03735	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
F0M17_RS03740	COG1012	belongs to the aldehyde dehydrogenase family
F0M17_RS03750	COG1473	amidohydrolase
F0M17_RS03750	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
F0M17_RS03755	COG1744	ABC transporter substrate-binding protein PnrA-like
F0M17_RS03760	COG3845	ABC transporter
F0M17_RS03765	COG4603	Belongs to the binding-protein-dependent transport system permease family
F0M17_RS03770	COG1079	Belongs to the binding-protein-dependent transport system permease family
F0M17_RS03785	COG0586	Pfam SNARE associated Golgi protein
F0M17_RS03790	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
F0M17_RS03800	COG3956	TIGRFAM MazG family protein
F0M17_RS03805	COG0148	phosphopyruvate hydratase activity
F0M17_RS03830	COG1252	NADH dehydrogenase
F0M17_RS03845	COG0531	amino acid
F0M17_RS03855	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
F0M17_RS03860	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
F0M17_RS03870	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
F0M17_RS03880	COG1331	Highly conserved protein containing a thioredoxin domain
F0M17_RS03885	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
F0M17_RS03890	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
F0M17_RS03915	COG0114	fumarate hydratase activity
F0M17_RS03920	COG0288	reversible hydration of carbon dioxide
F0M17_RS03940	COG1316	TRANSCRIPTIONal
F0M17_RS03945	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
F0M17_RS04030	COG0714	Associated with various cellular activities
F0M17_RS04035	COG0084	hydrolase, TatD family'
F0M17_RS04040	COG3583	domain protein
F0M17_RS04045	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
F0M17_RS04050	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
F0M17_RS04055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F0M17_RS04090	COG0488	(ABC) transporter
F0M17_RS04100	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
F0M17_RS04105	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
F0M17_RS04115	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
F0M17_RS04125	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
F0M17_RS04130	COG0193	aminoacyl-tRNA hydrolase activity
F0M17_RS04140	COG0822	iron-sulfur transferase activity
F0M17_RS04145	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
F0M17_RS04170	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
F0M17_RS04175	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
F0M17_RS04190	COG0477	Major facilitator Superfamily
F0M17_RS04205	COG4770	biotin carboxylase activity
F0M17_RS04225	COG0424	maF-like protein
F0M17_RS04230	COG2409	Drug exporters of the RND superfamily
F0M17_RS04240	COG1823	symporter activity
F0M17_RS04250	COG0346	lactoylglutathione lyase activity
F0M17_RS04265	COG0714	Associated with various cellular activities
F0M17_RS04285	COG0631	protein serine/threonine phosphatase activity
F0M17_RS04310	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
F0M17_RS04320	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
F0M17_RS04320	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
F0M17_RS04340	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
F0M17_RS04360	COG0363	glucosamine-6-phosphate deaminase activity
F0M17_RS04390	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
F0M17_RS04395	COG0154	amidase activity
F0M17_RS04400	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
F0M17_RS04425	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F0M17_RS04430	COG1846	Transcriptional regulator
F0M17_RS04435	COG2814	Major facilitator Superfamily
F0M17_RS04455	COG2814	Major facilitator Superfamily
F0M17_RS04465	COG1063	alcohol dehydrogenase
F0M17_RS04475	COG1609	Transcriptional regulator
F0M17_RS04480	COG1653	transport
F0M17_RS04485	COG1175	transmembrane transport
F0M17_RS04490	COG0395	ABC-type sugar transport system, permease component
F0M17_RS04495	COG1228	amidohydrolase
F0M17_RS04505	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
F0M17_RS04525	COG2873	o-acetylhomoserine
F0M17_RS04530	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
F0M17_RS04555	COG0423	glycine-tRNA ligase activity
F0M17_RS04570	COG2059	Chromate
F0M17_RS04595	COG0358	DNA primase activity
F0M17_RS04630	COG1929	Belongs to the glycerate kinase type-1 family
F0M17_RS04655	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F0M17_RS04665	COG0024	Methionine aminopeptidase
F0M17_RS04670	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
F0M17_RS04680	COG0156	8-amino-7-oxononanoate synthase activity
F0M17_RS04685	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
F0M17_RS04690	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
F0M17_RS04735	COG0076	glutamate decarboxylase activity
F0M17_RS04765	COG0438	transferase activity, transferring glycosyl groups
F0M17_RS04780	COG0052	Belongs to the universal ribosomal protein uS2 family
F0M17_RS04785	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
F0M17_RS04790	COG0528	UMP kinase activity
F0M17_RS04795	COG0233	cytoplasmic translational termination
F0M17_RS04810	COG1846	Transcriptional regulator
F0M17_RS04815	COG0697	spore germination
F0M17_RS04820	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F0M17_RS04830	COG3279	Response regulator of the LytR AlgR family
F0M17_RS04835	COG3275	phosphorelay sensor kinase activity
F0M17_RS04845	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F0M17_RS04860	COG0022	dehydrogenase e1 component
F0M17_RS04865	COG0508	dehydrogenase complex catalyzes the overall conversion of
F0M17_RS04875	COG0601	transmembrane transport
F0M17_RS04880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F0M17_RS04890	COG0747	negative chemotaxis
F0M17_RS04900	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F0M17_RS04920	COG1960	acyl-CoA dehydrogenase activity
F0M17_RS04925	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
F0M17_RS04930	COG0750	zinc metalloprotease
F0M17_RS04940	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
F0M17_RS04950	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
F0M17_RS04955	COG0456	acetyltransferase
F0M17_RS04975	COG0442	prolyl-tRNA aminoacylation
F0M17_RS04995	COG0779	Required for maturation of 30S ribosomal subunits
F0M17_RS05010	COG0481	GTPase activity
F0M17_RS05010	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
F0M17_RS05015	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
F0M17_RS05040	COG1595	DNA-templated transcription, initiation
F0M17_RS05050	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
F0M17_RS05065	COG0196	riboflavin kinase activity
F0M17_RS05075	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
F0M17_RS05085	COG1574	metal-dependent hydrolase with the TIM-barrel fold
F0M17_RS05090	COG3639	organic phosphonate transmembrane transporter activity
F0M17_RS05095	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
F0M17_RS05110	COG2188	Transcriptional regulator
F0M17_RS05120	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
F0M17_RS05135	COG1619	proteins homologs of microcin C7 resistance protein MccF
F0M17_RS05145	COG0589	response to stress
F0M17_RS05160	COG3181	Tripartite tricarboxylate transporter family receptor
F0M17_RS05165	COG3290	protein histidine kinase activity
F0M17_RS05170	COG4565	transcriptional regulatory protein
F0M17_RS05185	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
F0M17_RS05190	COG0022	dehydrogenase e1 component
F0M17_RS05200	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F0M17_RS05205	COG0318	PFAM AMP-dependent synthetase and ligase
F0M17_RS05210	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
F0M17_RS05215	COG3314	Sporulation integral membrane protein YlbJ
F0M17_RS05225	COG1397	ADP-ribosylglycohydrolase
F0M17_RS05240	COG1064	alcohol dehydrogenase
F0M17_RS05245	COG1185	polyribonucleotide nucleotidyltransferase activity
F0M17_RS05270	COG1234	tRNA 3'-trailer cleavage
F0M17_RS05280	COG2814	Major facilitator Superfamily
F0M17_RS05295	COG0028	Belongs to the TPP enzyme family
F0M17_RS05325	COG0179	Fumarylacetoacetate (FAA) hydrolase
F0M17_RS05355	COG0612	Peptidase, M16
F0M17_RS05370	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
F0M17_RS05385	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F0M17_RS05390	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
F0M17_RS05400	COG1125	glycine betaine transport
F0M17_RS05400	COG0517	IMP dehydrogenase activity
F0M17_RS05405	COG1174	glycine betaine transport
F0M17_RS05445	COG4139	cobalamin transport
F0M17_RS05450	COG1120	ATPase activity
F0M17_RS05470	COG1674	ftsk spoiiie
F0M17_RS05480	COG1546	Belongs to the CinA family
F0M17_RS05480	COG1058	Belongs to the CinA family
F0M17_RS05495	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
F0M17_RS05510	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
F0M17_RS05515	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
F0M17_RS05520	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
F0M17_RS05525	COG2813	Specifically methylates the guanine in position
F0M17_RS05530	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
F0M17_RS05545	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
F0M17_RS05555	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
F0M17_RS05560	COG0131	Imidazoleglycerol-phosphate dehydratase
F0M17_RS05565	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
F0M17_RS05570	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
F0M17_RS05595	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
F0M17_RS05600	COG0291	Belongs to the bacterial ribosomal protein bL35 family
F0M17_RS05605	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
F0M17_RS05610	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F0M17_RS05615	COG0494	nUDIX hydrolase
F0M17_RS05625	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
F0M17_RS05630	COG0072	phenylalanine-tRNA ligase activity
F0M17_RS05630	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F0M17_RS05670	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
F0M17_RS05675	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
F0M17_RS05680	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
F0M17_RS05685	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F0M17_RS05690	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
F0M17_RS05695	COG1438	arginine binding
F0M17_RS05710	COG0165	Argininosuccinate lyase
F0M17_RS05720	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
F0M17_RS05730	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
F0M17_RS05760	COG0647	UMP catabolic process
F0M17_RS05770	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
F0M17_RS05775	COG0497	DNA recombination
F0M17_RS05780	COG0504	CTP synthase activity
F0M17_RS05785	COG0494	nUDIX hydrolase
F0M17_RS05790	COG4974	Belongs to the 'phage' integrase family
F0M17_RS05795	COG0494	nUDIX hydrolase
F0M17_RS05800	COG3655	Transcriptional regulator
F0M17_RS05815	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
F0M17_RS05820	COG2079	MmgE PrpD family protein
F0M17_RS05825	COG2186	Transcriptional regulator
F0M17_RS05835	COG4565	transcriptional regulatory protein
F0M17_RS05840	COG3290	protein histidine kinase activity
F0M17_RS05845	COG1301	dicarboxylic acid transport
F0M17_RS05870	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
F0M17_RS05885	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
F0M17_RS05890	COG1160	GTP binding
F0M17_RS05900	COG0384	phenazine biosynthesis protein PhzF
F0M17_RS05905	COG0488	(ABC) transporter
F0M17_RS05915	COG3189	MarR family transcriptional regulator
F0M17_RS05920	COG1716	ATPase activity
F0M17_RS05940	COG1192	Involved in chromosome partitioning
F0M17_RS05945	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
F0M17_RS05975	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
F0M17_RS05980	COG0515	serine threonine protein kinase
F0M17_RS05980	COG2815	serine threonine protein kinase
F0M17_RS05990	COG1674	ftsk spoiiie
F0M17_RS06030	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
F0M17_RS06035	COG2884	Cell division ATP-binding protein ftsE
F0M17_RS06045	COG1196	nuclear chromosome segregation
F0M17_RS06045	COG0739	heme binding
F0M17_RS06045	COG0741	lytic transglycosylase activity
F0M17_RS06050	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
F0M17_RS06065	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
F0M17_RS06070	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
F0M17_RS06100	COG1321	iron dependent repressor
F0M17_RS06100	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F0M17_RS06105	COG0483	inositol monophosphate 1-phosphatase activity
F0M17_RS06115	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
F0M17_RS06120	COG1595	DNA-templated transcription, initiation
F0M17_RS06135	COG0508	dehydrogenase complex catalyzes the overall conversion of
F0M17_RS06135	COG0567	Dehydrogenase, E1 component
F0M17_RS06140	COG1253	flavin adenine dinucleotide binding
F0M17_RS06145	COG1253	flavin adenine dinucleotide binding
F0M17_RS06150	COG3842	ATPase activity
F0M17_RS06185	COG0537	adenosine 5'-monophosphoramidase activity
F0M17_RS06200	COG1643	Atp-dependent helicase
F0M17_RS06215	COG1116	anion transmembrane transporter activity
F0M17_RS06235	COG0018	arginyl-trna synthetase
F0M17_RS06240	COG0019	diaminopimelate decarboxylase activity
F0M17_RS06245	COG0460	homoserine dehydrogenase
F0M17_RS06250	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
F0M17_RS06255	COG0083	homoserine kinase activity
F0M17_RS06265	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
F0M17_RS06280	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
F0M17_RS06290	COG0356	it plays a direct role in the translocation of protons across the membrane
F0M17_RS06295	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
F0M17_RS06300	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
F0M17_RS06305	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
F0M17_RS06310	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
F0M17_RS06315	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
F0M17_RS06320	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
F0M17_RS06325	COG0355	proton-transporting ATP synthase activity, rotational mechanism
F0M17_RS06345	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
F0M17_RS06390	COG1335	isochorismatase
F0M17_RS06395	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
F0M17_RS06400	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
F0M17_RS06410	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
F0M17_RS06415	COG1234	tRNA 3'-trailer cleavage
F0M17_RS06425	COG1012	belongs to the aldehyde dehydrogenase family
F0M17_RS06435	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
F0M17_RS06450	COG2124	cytochrome p450
F0M17_RS06460	COG1414	Transcriptional regulator
F0M17_RS06465	COG0477	Major facilitator Superfamily
F0M17_RS06480	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
F0M17_RS06485	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
F0M17_RS06495	COG2188	Transcriptional regulator
F0M17_RS06500	COG1131	(ABC) transporter
F0M17_RS06515	COG2176	DNA-directed DNA polymerase activity
F0M17_RS06525	COG0420	3'-5' exonuclease activity
F0M17_RS06530	COG0419	ATPase involved in DNA repair
F0M17_RS06555	COG0366	Alpha amylase catalytic
F0M17_RS06560	COG2182	Extracellular solute-binding protein
F0M17_RS06565	COG1175	transmembrane transport
F0M17_RS06570	COG3833	ABC-type maltose transport systems, permease component
F0M17_RS06585	COG0477	Major facilitator Superfamily
F0M17_RS06600	COG0488	(ABC) transporter
F0M17_RS06605	COG0640	Transcriptional regulator
F0M17_RS06620	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
F0M17_RS06640	COG1012	belongs to the aldehyde dehydrogenase family
F0M17_RS06645	COG1802	Transcriptional regulator
F0M17_RS06660	COG1136	(ABC) transporter
F0M17_RS06660	COG0577	efflux transmembrane transporter activity
F0M17_RS06670	COG0129	dihydroxy-acid dehydratase activity
F0M17_RS06690	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
F0M17_RS06695	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
F0M17_RS06710	COG1876	peptidase activity
F0M17_RS06740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F0M17_RS06745	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
F0M17_RS06750	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
F0M17_RS06770	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
F0M17_RS06790	COG1815	bacterial-type flagellum-dependent cell motility
F0M17_RS06810	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
F0M17_RS06820	COG1157	protein secretion by the type III secretion system
F0M17_RS06830	COG0791	NLP P60 protein
F0M17_RS06840	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
F0M17_RS06855	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
F0M17_RS06880	COG1338	Plays a role in the flagellum-specific transport system
F0M17_RS06895	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
F0M17_RS06900	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
F0M17_RS06910	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
F0M17_RS06915	COG2197	response regulator
F0M17_RS06945	COG1764	response to oxidative stress
F0M17_RS06950	COG1846	Transcriptional regulator
F0M17_RS06970	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F0M17_RS06980	COG0579	oxidoreductase
F0M17_RS06985	COG0747	negative chemotaxis
F0M17_RS06990	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F0M17_RS07020	COG1846	Transcriptional regulator
F0M17_RS07025	COG0702	epimerase
F0M17_RS07040	COG0142	geranyltranstransferase activity
F0M17_RS07050	COG1233	COG1233 Phytoene dehydrogenase and related
F0M17_RS07070	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
F0M17_RS07090	COG0440	acetolactate synthase activity
F0M17_RS07095	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
F0M17_RS07105	COG2226	methyltransferase
F0M17_RS07110	COG3764	Sortase (surface protein transpeptidase)
F0M17_RS07135	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F0M17_RS07160	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
F0M17_RS07195	COG1432	Conserved Protein
F0M17_RS07205	COG2197	response regulator
F0M17_RS07210	COG4585	Histidine kinase
F0M17_RS07215	COG0473	3-isopropylmalate dehydrogenase activity
F0M17_RS07220	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
F0M17_RS07225	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
F0M17_RS07235	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
F0M17_RS07270	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
F0M17_RS07275	COG1414	Transcriptional regulator
F0M17_RS07280	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
F0M17_RS07285	COG0066	3-isopropylmalate dehydratase activity
F0M17_RS07290	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
F0M17_RS07300	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
F0M17_RS07305	COG1181	Belongs to the D-alanine--D-alanine ligase family
F0M17_RS07315	COG1316	TRANSCRIPTIONal
F0M17_RS07320	COG1461	Dihydroxyacetone kinase
F0M17_RS07330	COG0742	ribosomal rna small subunit methyltransferase
F0M17_RS07345	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
F0M17_RS07350	COG1210	Utp--glucose-1-phosphate uridylyltransferase
F0M17_RS07355	COG1316	TRANSCRIPTIONal
F0M17_RS07365	COG1388	LysM domain
F0M17_RS07365	COG1134	teichoic acid transport
F0M17_RS07385	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
F0M17_RS07405	COG0333	Belongs to the bacterial ribosomal protein bL32 family
F0M17_RS07410	COG0571	ribonuclease III activity
F0M17_RS07415	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
F0M17_RS07425	COG1196	nuclear chromosome segregation
F0M17_RS07450	COG2755	lipolytic protein G-D-S-L family
F0M17_RS07450	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
F0M17_RS07455	COG2094	Belongs to the DNA glycosylase MPG family
F0M17_RS07475	COG1295	ribonuclease BN
F0M17_RS07555	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F0M17_RS07560	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F0M17_RS07565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F0M17_RS07570	COG2514	catechol 2,3-dioxygenase activity
F0M17_RS07585	COG4607	ABC-type enterochelin transport system periplasmic component
F0M17_RS07590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F0M17_RS07595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F0M17_RS07605	COG1280	lysine exporter protein (LysE YggA)
F0M17_RS07610	COG0228	four-way junction DNA binding
F0M17_RS07615	COG1837	Belongs to the UPF0109 family
F0M17_RS07620	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
F0M17_RS07625	COG0336	Belongs to the RNA methyltransferase TrmD family
F0M17_RS07630	COG0335	large ribosomal subunit rRNA binding
F0M17_RS07635	COG0681	Belongs to the peptidase S26 family
F0M17_RS07650	COG0681	Belongs to the peptidase S26 family
F0M17_RS07655	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
F0M17_RS07665	COG0792	nuclease activity
F0M17_RS07675	COG0758	DNA mediated transformation
F0M17_RS07675	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
F0M17_RS07680	COG4974	Belongs to the 'phage' integrase family
F0M17_RS07700	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F0M17_RS07705	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F0M17_RS07720	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
F0M17_RS07760	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
F0M17_RS07785	COG2261	transglycosylase associated protein
F0M17_RS07790	COG3265	gluconokinase activity
F0M17_RS07795	COG2610	gluconate transmembrane transporter activity
F0M17_RS07805	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
F0M17_RS07825	COG2130	NADP-dependent
F0M17_RS07840	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
F0M17_RS07850	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
F0M17_RS07855	COG1045	serine acetyltransferase
F0M17_RS07865	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
F0M17_RS07870	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
F0M17_RS07880	COG3022	response to hydroperoxide
F0M17_RS07905	COG0242	peptide deformylase activity
F0M17_RS07910	COG1960	acyl-CoA dehydrogenase activity
F0M17_RS07960	COG0488	(ABC) transporter
F0M17_RS07985	COG1028	Short-chain dehydrogenase reductase Sdr
F0M17_RS07990	COG1028	Short-chain dehydrogenase reductase Sdr
F0M17_RS08005	COG1119	ATPase activity
F0M17_RS08020	COG0254	rRNA binding
F0M17_RS08040	COG2186	Transcriptional regulator
F0M17_RS08045	COG0747	negative chemotaxis
F0M17_RS08055	COG0444	Belongs to the ABC transporter superfamily
F0M17_RS08060	COG4608	Belongs to the ABC transporter superfamily
F0M17_RS08065	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F0M17_RS08070	COG1940	carbohydrate kinase activity
F0M17_RS08075	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
F0M17_RS08120	COG1028	Short-chain dehydrogenase reductase Sdr
F0M17_RS08130	COG0438	transferase activity, transferring glycosyl groups
F0M17_RS08135	COG2267	carboxylic ester hydrolase activity
F0M17_RS08150	COG3976	FMN-binding domain protein
F0M17_RS08150	COG1053	succinate dehydrogenase
F0M17_RS08165	COG0745	RESPONSE REGULATOR receiver
F0M17_RS08170	COG0642	Histidine kinase
F0M17_RS08180	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F0M17_RS08200	COG1968	undecaprenyl-diphosphatase activity
F0M17_RS08205	COG0215	cysteine-tRNA ligase activity
F0M17_RS08215	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F0M17_RS08220	COG0517	IMP dehydrogenase activity
F0M17_RS08220	COG1994	Peptidase M50
F0M17_RS08230	COG1222	aaa ATPase
F0M17_RS08245	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
F0M17_RS08270	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
F0M17_RS08275	COG0805	protein transport
F0M17_RS08285	COG1228	amidohydrolase
F0M17_RS08290	COG1216	Glycosyl transferase, family 2
F0M17_RS08310	COG2226	methyltransferase
F0M17_RS08315	COG0242	peptide deformylase activity
F0M17_RS08365	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
F0M17_RS08370	COG1845	cytochrome c oxidase, subunit III
F0M17_RS08375	COG2010	Cytochrome c
F0M17_RS08380	COG0723	plastoquinol--plastocyanin reductase activity
F0M17_RS08385	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
F0M17_RS08390	COG2188	Transcriptional regulator
F0M17_RS08400	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
F0M17_RS08405	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
F0M17_RS08425	COG0167	dihydroorotate dehydrogenase activity
F0M17_RS08435	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
F0M17_RS08440	COG1381	Involved in DNA repair and RecF pathway recombination
F0M17_RS08445	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
F0M17_RS08455	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
F0M17_RS08465	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
F0M17_RS08485	COG0484	heat shock protein binding
F0M17_RS08490	COG1420	regulation of RNA biosynthetic process
F0M17_RS08510	COG0481	GTPase activity
F0M17_RS08520	COG0268	Binds directly to 16S ribosomal RNA
F0M17_RS08535	COG2333	competence protein COMEC
F0M17_RS08535	COG0658	competence protein
F0M17_RS08545	COG1307	EDD domain protein, DegV family
F0M17_RS08550	COG0495	leucyl-tRNA aminoacylation
F0M17_RS08560	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
F0M17_RS08565	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
F0M17_RS08570	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
F0M17_RS08575	COG2390	Transcriptional regulator
F0M17_RS08590	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
F0M17_RS08600	COG1758	RNA polymerase activity
F0M17_RS08605	COG0194	GDP metabolic process
F0M17_RS08615	COG0284	orotidine-5'-phosphate decarboxylase activity
F0M17_RS08620	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
F0M17_RS08625	COG0505	Belongs to the CarA family
F0M17_RS08635	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
F0M17_RS08640	COG0540	Belongs to the ATCase OTCase family
F0M17_RS08645	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
F0M17_RS08655	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
F0M17_RS08660	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
F0M17_RS08670	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
F0M17_RS08675	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
F0M17_RS08680	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
F0M17_RS08685	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
F0M17_RS08695	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
F0M17_RS08700	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
F0M17_RS08715	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
F0M17_RS08725	COG1490	D-aminoacyl-tRNA deacylase activity
F0M17_RS08730	COG1960	acyl-CoA dehydrogenase activity
F0M17_RS08740	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
F0M17_RS08745	COG0124	histidyl-tRNA synthetase
F0M17_RS08750	COG1196	nuclear chromosome segregation
F0M17_RS08760	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
F0M17_RS08765	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
F0M17_RS08775	COG1862	Preprotein translocase
F0M17_RS08780	COG2255	four-way junction helicase activity
F0M17_RS08785	COG0632	four-way junction helicase activity
F0M17_RS08790	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
F0M17_RS08795	COG0217	transcriptional regulatory protein
F0M17_RS08800	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
F0M17_RS08820	COG0339	signal peptide processing
F0M17_RS08845	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
F0M17_RS08855	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
F0M17_RS08880	COG0587	DNA-directed DNA polymerase activity
F0M17_RS08895	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F0M17_RS08905	COG2135	peptidase activity
F0M17_RS08950	COG2814	Major facilitator Superfamily
F0M17_RS08955	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
F0M17_RS08960	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
F0M17_RS08965	COG1780	Probably involved in ribonucleotide reductase function
F0M17_RS08975	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
F0M17_RS08980	COG0028	Belongs to the TPP enzyme family
F0M17_RS08985	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
F0M17_RS08995	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
F0M17_RS09020	COG0488	(ABC) transporter
F0M17_RS09030	COG1053	succinate dehydrogenase
F0M17_RS09035	COG0583	DNA-binding transcription factor activity
F0M17_RS09055	COG0300	oxidoreductase activity
F0M17_RS09060	COG1522	sequence-specific DNA binding
F0M17_RS09065	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
F0M17_RS09070	COG1113	amino acid transport
F0M17_RS09085	COG0598	Magnesium transport protein CorA
F0M17_RS09120	COG0799	negative regulation of ribosome biogenesis
F0M17_RS09130	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
F0M17_RS09140	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
F0M17_RS09145	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
F0M17_RS09150	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
F0M17_RS09155	COG0211	Belongs to the bacterial ribosomal protein bL27 family
F0M17_RS09160	COG0261	This protein binds to 23S rRNA in the presence of protein L20
F0M17_RS09165	COG1530	ribonuclease E activity
F0M17_RS09190	COG0105	UTP biosynthetic process
F0M17_RS09200	COG0285	dihydrofolate synthase activity
F0M17_RS09205	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
F0M17_RS09215	COG3973	AAA domain
F0M17_RS09220	COG4585	Histidine kinase
F0M17_RS09225	COG2197	response regulator
F0M17_RS09230	COG2409	Drug exporters of the RND superfamily
F0M17_RS09275	COG0175	sulfate reduction
F0M17_RS09280	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F0M17_RS09300	COG0525	valine-tRNA ligase activity
F0M17_RS09315	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
F0M17_RS09320	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
F0M17_RS09325	COG0740	serine-type endopeptidase activity
F0M17_RS09335	COG0544	peptidyl-prolyl cis-trans isomerase activity
F0M17_RS09365	COG0698	ribose 5-phosphate isomerase
F0M17_RS09390	COG1946	Acyl-CoA thioesterase
F0M17_RS09395	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F0M17_RS09395	COG1017	nitric oxide dioxygenase activity
F0M17_RS09415	COG0629	single-stranded DNA binding
F0M17_RS09435	COG0738	Major facilitator superfamily
F0M17_RS09440	COG1522	sequence-specific DNA binding
F0M17_RS09445	COG1280	lysine exporter protein (LysE YggA)
F0M17_RS09450	COG1122	ATPase activity
F0M17_RS09455	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
F0M17_RS09460	COG1268	BioY protein
F0M17_RS09475	COG2151	metal-sulfur cluster biosynthetic enzyme
F0M17_RS09480	COG2151	metal-sulfur cluster biosynthetic enzyme
F0M17_RS09485	COG0396	ATPase activity
F0M17_RS09505	COG1131	(ABC) transporter
F0M17_RS09520	COG0109	protoheme IX farnesyltransferase activity
F0M17_RS09530	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
F0M17_RS09550	COG0363	glucosamine-6-phosphate deaminase activity
F0M17_RS09560	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
F0M17_RS09565	COG0569	domain protein
F0M17_RS09570	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
F0M17_RS09575	COG0149	triose-phosphate isomerase activity
F0M17_RS09580	COG0126	phosphoglycerate kinase activity
F0M17_RS09595	COG1481	regulation of sporulation
F0M17_RS09600	COG0391	Required for morphogenesis under gluconeogenic growth conditions
F0M17_RS09605	COG1660	Displays ATPase and GTPase activities
F0M17_RS09610	COG0322	excinuclease ABC activity
F0M17_RS09655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F0M17_RS09670	COG4106	trans-aconitate 2-methyltransferase activity
F0M17_RS09710	COG1846	Transcriptional regulator
F0M17_RS09720	COG0556	nucleotide-excision repair
F0M17_RS09730	COG0237	dephospho-CoA kinase activity
F0M17_RS09730	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
F0M17_RS09735	COG1739	Uncharacterized protein family UPF0029
F0M17_RS09740	COG2813	Specifically methylates the guanine in position
F0M17_RS09755	COG0539	negative regulation of cytoplasmic translation
F0M17_RS09805	COG0469	pyruvate kinase activity
F0M17_RS09815	COG0069	glutamate synthase activity
F0M17_RS09815	COG0070	glutamate synthase
F0M17_RS09815	COG0067	glutamate synthase
F0M17_RS09830	COG0159	tryptophan synthase activity
F0M17_RS09835	COG0133	tryptophan synthase activity
F0M17_RS09840	COG0134	indole-3-glycerol-phosphate synthase activity
F0M17_RS09860	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
F0M17_RS09885	COG0107	imidazoleglycerol-phosphate synthase activity
F0M17_RS09890	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
F0M17_RS09895	COG0140	phosphoribosyl-ATP diphosphatase activity
F0M17_RS09900	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
F0M17_RS09905	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
F0M17_RS09905	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
F0M17_RS09925	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
F0M17_RS09935	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
F0M17_RS09940	COG0242	peptide deformylase activity
F0M17_RS09990	COG3135	benzoate transporter
F0M17_RS10010	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
F0M17_RS10020	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
F0M17_RS10050	COG0183	Belongs to the thiolase family
F0M17_RS10055	COG1250	3-hydroxyacyl-CoA dehydrogenase
F0M17_RS10055	COG1024	Enoyl-CoA hydratase
F0M17_RS10060	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F0M17_RS10070	COG0667	Aldo Keto reductase
F0M17_RS10075	COG0137	argininosuccinate synthase activity
F0M17_RS10105	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
F0M17_RS10115	COG2226	methyltransferase
F0M17_RS10120	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
F0M17_RS10130	COG0531	amino acid
F0M17_RS10135	COG0569	domain protein
F0M17_RS10160	COG0756	dUTP diphosphatase activity
F0M17_RS10195	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
F0M17_RS10200	COG4988	ABC transporter
F0M17_RS10205	COG1294	oxidase, subunit
F0M17_RS10210	COG1271	oxidase subunit
F0M17_RS10235	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
F0M17_RS10245	COG2223	nitrite transmembrane transporter activity
F0M17_RS10255	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
F0M17_RS10260	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F0M17_RS10265	COG0508	dehydrogenase complex catalyzes the overall conversion of
F0M17_RS10280	COG0321	lipoyl(octanoyl) transferase activity
F0M17_RS10285	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
F0M17_RS10300	COG0174	glutamine synthetase
F0M17_RS10310	COG0590	tRNA wobble adenosine to inosine editing
F0M17_RS10320	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
F0M17_RS10325	COG0174	glutamine synthetase
F0M17_RS10330	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
F0M17_RS10345	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
F0M17_RS10350	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
F0M17_RS10355	COG0587	DNA-directed DNA polymerase activity
F0M17_RS10365	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
F0M17_RS10370	COG3599	regulation of cell shape
F0M17_RS10380	COG1799	cell septum assembly
F0M17_RS10385	COG1496	oxidoreductase activity
F0M17_RS10390	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
F0M17_RS10395	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
F0M17_RS10400	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
F0M17_RS10405	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
F0M17_RS10410	COG0772	Belongs to the SEDS family
F0M17_RS10415	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
F0M17_RS10420	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
F0M17_RS10435	COG0768	penicillin binding
F0M17_RS10445	COG0275	rRNA processing
F0M17_RS10450	COG2001	Belongs to the MraZ family
F0M17_RS10460	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
F0M17_RS10465	COG0142	geranyltranstransferase activity
F0M17_RS10485	COG2902	Dehydrogenase
F0M17_RS10515	COG0653	protein targeting
F0M17_RS10520	COG3214	Protein conserved in bacteria
F0M17_RS10525	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
F0M17_RS10535	COG5401	PFAM Sporulation and spore germination
F0M17_RS10540	COG5002	protein histidine kinase activity
F0M17_RS10540	COG5000	phosphorelay sensor kinase activity
F0M17_RS10545	COG0745	RESPONSE REGULATOR receiver
F0M17_RS10565	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F0M17_RS10570	COG0601	transmembrane transport
F0M17_RS10575	COG4533	DNA binding
F0M17_RS10585	COG0482	sulfurtransferase activity
F0M17_RS10600	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
F0M17_RS10620	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
F0M17_RS10635	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
F0M17_RS10645	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F0M17_RS10655	COG1842	Phage shock protein A
F0M17_RS10675	COG1615	UPF0182 protein
F0M17_RS10680	COG3480	Lon protease (S16) C-terminal proteolytic domain
F0M17_RS10710	COG0210	DNA helicase
F0M17_RS10730	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
F0M17_RS10735	COG2011	ABC-type metal ion transport system permease component
F0M17_RS10740	COG1464	Belongs to the NlpA lipoprotein family
F0M17_RS10745	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
F0M17_RS10750	COG0113	porphobilinogen synthase activity
F0M17_RS10760	COG0181	hydroxymethylbilane synthase activity
F0M17_RS10765	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
F0M17_RS10770	COG3253	May function as heme-dependent peroxidase
F0M17_RS10775	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
F0M17_RS10780	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
F0M17_RS10785	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
F0M17_RS10790	COG1309	transcriptional regulator
F0M17_RS10810	COG2189	Belongs to the N(4) N(6)-methyltransferase family
F0M17_RS10820	COG0006	proline dipeptidase activity
F0M17_RS10830	COG2239	Acts as a magnesium transporter
F0M17_RS10870	COG1611	Belongs to the LOG family
F0M17_RS10875	COG1126	abc transporter atp-binding protein
F0M17_RS10880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0M17_RS10885	COG0765	amino acid transport
F0M17_RS10890	COG0765	amino acid transport
F0M17_RS10895	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F0M17_RS10900	COG2171	N-acyltransferase activity
F0M17_RS10940	COG1217	gtp-binding protein TYPA
F0M17_RS10955	COG2022	thiamine diphosphate biosynthetic process
F0M17_RS10965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F0M17_RS10980	COG1765	OsmC-like protein
F0M17_RS11065	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
F0M17_RS11070	COG0183	Belongs to the thiolase family
F0M17_RS11075	COG1960	acyl-CoA dehydrogenase activity
F0M17_RS11080	COG0823	Involved in the tonB-independent uptake of proteins
F0M17_RS11085	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F0M17_RS11110	COG2267	carboxylic ester hydrolase activity
F0M17_RS11150	COG0596	Alpha beta hydrolase
F0M17_RS11165	COG0012	GTP binding
F0M17_RS11170	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
F0M17_RS11180	COG1570	exodeoxyribonuclease VII activity
F0M17_RS11185	COG1722	exodeoxyribonuclease VII activity
F0M17_RS11190	COG2326	polyphosphate kinase activity
F0M17_RS11205	COG1051	belongs to the nudix hydrolase family
F0M17_RS11210	COG1522	sequence-specific DNA binding
F0M17_RS11245	COG0519	Catalyzes the synthesis of GMP from XMP
F0M17_RS11245	COG0518	GMP synthase (glutamine-hydrolyzing) activity
F0M17_RS11260	COG0516	GMP reductase activity
F0M17_RS11280	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
F0M17_RS11280	COG2755	lipolytic protein G-D-S-L family
F0M17_RS11285	COG0459	protein refolding
F0M17_RS11290	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
F0M17_RS11295	COG0833	amino acid
F0M17_RS11305	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
F0M17_RS11315	COG2188	Transcriptional regulator
F0M17_RS11320	COG2807	transmembrane transport
F0M17_RS11330	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
F0M17_RS11335	COG1247	-acetyltransferase
F0M17_RS11345	COG0802	atpase or kinase
F0M17_RS11350	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
F0M17_RS11355	COG1970	mechanosensitive ion channel activity
F0M17_RS11360	COG1072	(Pantothenic acid kinase))
F0M17_RS11365	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
F0M17_RS11370	COG0736	holo-[acyl-carrier-protein] synthase activity
F0M17_RS11375	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
F0M17_RS11380	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
F0M17_RS11385	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
F0M17_RS11390	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
F0M17_RS11395	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
F0M17_RS11400	COG0101	tRNA pseudouridine synthase activity
F0M17_RS11415	COG0203	ribosomal protein L17
F0M17_RS11420	COG0202	RNA polymerase activity
F0M17_RS11425	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
F0M17_RS11430	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
F0M17_RS11435	COG0257	Belongs to the bacterial ribosomal protein bL36 family
F0M17_RS11440	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
F0M17_RS11450	COG0563	adenylate kinase activity
F0M17_RS11460	COG0200	Binds to the 23S rRNA
F0M17_RS11465	COG1841	ribosomal large subunit assembly
F0M17_RS11470	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
F0M17_RS11475	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
F0M17_RS11480	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
F0M17_RS11485	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
F0M17_RS11490	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
F0M17_RS11495	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
F0M17_RS11500	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
F0M17_RS11520	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
F0M17_RS11530	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
F0M17_RS11535	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
F0M17_RS11540	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
F0M17_RS11545	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
F0M17_RS11550	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
F0M17_RS11555	COG0089	rRNA binding
F0M17_RS11560	COG0088	Forms part of the polypeptide exit tunnel
F0M17_RS11565	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
F0M17_RS11570	COG0051	transcription antitermination factor activity, RNA binding
F0M17_RS11580	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
F0M17_RS11585	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
F0M17_RS11590	COG0049	tRNA binding
F0M17_RS11595	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
F0M17_RS11600	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
F0M17_RS11605	COG0085	RNA polymerase activity
F0M17_RS11620	COG0222	ribosome binding
F0M17_RS11625	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
F0M17_RS11630	COG0081	regulation of translation
F0M17_RS11635	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
F0M17_RS11640	COG0250	Participates in transcription elongation, termination and antitermination
F0M17_RS11655	COG0436	Aminotransferase
F0M17_RS11660	COG2197	response regulator
F0M17_RS11690	COG0354	folic acid binding
F0M17_RS11695	COG3485	protocatechuate 3,4-dioxygenase
F0M17_RS11705	COG0745	RESPONSE REGULATOR receiver
F0M17_RS11710	COG0456	acetyltransferase
F0M17_RS11715	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
F0M17_RS11730	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
F0M17_RS11745	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
F0M17_RS11750	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F0M17_RS11755	COG0812	UDP-N-acetylmuramate dehydrogenase activity
F0M17_RS11760	COG0738	Major facilitator superfamily
F0M17_RS11770	COG2030	dehydratase
F0M17_RS11785	COG2357	RelA SpoT domain protein
F0M17_RS11835	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F0M17_RS11845	COG1666	GTP binding
F0M17_RS11855	COG0501	Belongs to the peptidase M48B family
F0M17_RS11875	COG0733	neurotransmitter:sodium symporter activity
F0M17_RS11895	COG0142	geranyltranstransferase activity
F0M17_RS11910	COG0765	amino acid transport
F0M17_RS11915	COG1126	abc transporter atp-binding protein
F0M17_RS11920	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
F0M17_RS11930	COG4948	Mandelate Racemase Muconate Lactonizing
F0M17_RS11945	COG0508	dehydrogenase complex catalyzes the overall conversion of
F0M17_RS11950	COG0022	dehydrogenase e1 component
F0M17_RS11965	COG1024	Enoyl-CoA hydratase
F0M17_RS11970	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F0M17_RS11975	COG2151	metal-sulfur cluster biosynthetic enzyme
F0M17_RS11980	COG3396	Phenylacetate-CoA oxygenase
F0M17_RS11985	COG3460	Phenylacetate-CoA oxygenase
F0M17_RS11990	COG3396	Phenylacetate-CoA oxygenase
F0M17_RS11995	COG2259	Doxx family
F0M17_RS12000	COG1126	abc transporter atp-binding protein
F0M17_RS12005	COG0765	amino acid transport
F0M17_RS12015	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
F0M17_RS12020	COG2050	protein possibly involved in aromatic compounds catabolism
F0M17_RS12045	COG1012	belongs to the aldehyde dehydrogenase family
F0M17_RS12045	COG2030	dehydratase
F0M17_RS12070	COG1250	3-hydroxyacyl-CoA dehydrogenase
F0M17_RS12075	COG1024	Enoyl-CoA hydratase
F0M17_RS12085	COG0477	Major facilitator Superfamily
F0M17_RS12095	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
F0M17_RS12120	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
F0M17_RS12130	COG0785	Cytochrome C biogenesis protein
F0M17_RS12135	COG3118	belongs to the thioredoxin family
F0M17_RS12140	COG0406	alpha-ribazole phosphatase activity
F0M17_RS12150	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
F0M17_RS12175	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
F0M17_RS12180	COG0640	Transcriptional regulator
F0M17_RS12185	COG0123	including yeast histone deacetylase and acetoin utilization protein
F0M17_RS12190	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
F0M17_RS12195	COG0569	domain protein
F0M17_RS12200	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
F0M17_RS12205	COG1082	Xylose isomerase domain protein TIM barrel
F0M17_RS12210	COG0248	Ppx GppA phosphatase
F0M17_RS12215	COG1754	DNA topoisomerase type I activity
F0M17_RS12215	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
F0M17_RS12225	COG2890	protein-(glutamine-N5) methyltransferase activity
F0M17_RS12235	COG1054	Belongs to the UPF0176 family
F0M17_RS12245	COG1111	helicase
F0M17_RS12245	COG1205	dead DEAH box helicase
F0M17_RS12285	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
F0M17_RS12285	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
F0M17_RS12295	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
F0M17_RS12300	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F0M17_RS12305	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
F0M17_RS12325	COG0251	oxidation-reduction process
F0M17_RS12340	COG1132	(ABC) transporter
F0M17_RS12345	COG1132	(ABC) transporter
F0M17_RS12355	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
F0M17_RS12360	COG0151	Belongs to the GarS family
F0M17_RS12380	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
F0M17_RS12385	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
F0M17_RS12400	COG0542	response to heat
F0M17_RS12415	COG3304	Inner membrane component domain
F0M17_RS12420	COG0220	tRNA (guanine-N7-)-methyltransferase activity
F0M17_RS12430	COG0789	Transcriptional regulator
F0M17_RS12435	COG0484	heat shock protein binding
F0M17_RS12440	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
F0M17_RS12445	COG0443	Heat shock 70 kDa protein
F0M17_RS12465	COG2409	Drug exporters of the RND superfamily
F0M17_RS12475	COG1280	lysine exporter protein (LysE YggA)
F0M17_RS12490	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F0M17_RS12500	COG1122	ATPase activity
F0M17_RS12505	COG4721	ABC-type cobalt transport system, permease component
F0M17_RS12515	COG1320	monovalent cation:proton antiporter activity
F0M17_RS12520	COG2212	antiporter activity
F0M17_RS12525	COG1863	multisubunit Na H antiporter MnhE subunit
F0M17_RS12530	COG0651	ATP synthesis coupled electron transport
F0M17_RS12535	COG1006	Multisubunit Na H antiporter MnhC subunit
F0M17_RS12540	COG2111	Na H antiporter
F0M17_RS12540	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
F0M17_RS12550	COG0717	Belongs to the dCTP deaminase family
F0M17_RS12560	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
F0M17_RS12560	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
F0M17_RS12580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0M17_RS12585	COG0765	amino acid transport
F0M17_RS12590	COG1126	abc transporter atp-binding protein
F0M17_RS12595	COG0433	COG0433 Predicted ATPase
F0M17_RS12640	COG0776	regulation of translation
F0M17_RS12645	COG0776	regulation of translation
F0M17_RS12660	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
F0M17_RS12665	COG0267	Belongs to the bacterial ribosomal protein bL33 family
F0M17_RS12670	COG0227	Belongs to the bacterial ribosomal protein bL28 family
F0M17_RS12675	COG1846	Transcriptional regulator
F0M17_RS12680	COG1177	transmembrane transport
F0M17_RS12690	COG3842	ATPase activity
F0M17_RS12705	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
F0M17_RS12740	COG0277	FAD linked oxidase domain protein
F0M17_RS12755	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
F0M17_RS12765	COG1012	belongs to the aldehyde dehydrogenase family
F0M17_RS12775	COG2207	Transcriptional regulator
F0M17_RS12780	COG3226	Transcriptional regulator
F0M17_RS12795	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F0M17_RS12835	COG1902	pentaerythritol trinitrate reductase activity
F0M17_RS12840	COG2239	Acts as a magnesium transporter
F0M17_RS12850	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
F0M17_RS12855	COG0509	glycine decarboxylation via glycine cleavage system
F0M17_RS12860	COG0404	The glycine cleavage system catalyzes the degradation of glycine
F0M17_RS12865	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
F0M17_RS12865	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
F0M17_RS12880	COG0531	amino acid
F0M17_RS12885	COG0328	RNA-DNA hybrid ribonuclease activity
F0M17_RS12895	COG0435	Glutathione S-transferase
F0M17_RS12910	COG1132	(ABC) transporter
F0M17_RS12920	COG1120	ATPase activity
F0M17_RS12925	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F0M17_RS12930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F0M17_RS12935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F0M17_RS12950	COG1136	(ABC) transporter
F0M17_RS12950	COG0577	efflux transmembrane transporter activity
F0M17_RS12995	COG1309	transcriptional regulator
F0M17_RS13000	COG1960	acyl-CoA dehydrogenase activity
F0M17_RS13005	COG1643	Atp-dependent helicase
F0M17_RS13010	COG0596	Alpha beta hydrolase
F0M17_RS13015	COG0667	Aldo Keto reductase
F0M17_RS13020	COG1012	belongs to the aldehyde dehydrogenase family
F0M17_RS13070	COG4946	Tricorn protease homolog
F0M17_RS13070	COG0823	Involved in the tonB-independent uptake of proteins
F0M17_RS13070	COG1506	peptidase
F0M17_RS13080	COG2860	membrane
F0M17_RS13095	COG0477	Major facilitator Superfamily
F0M17_RS13100	COG1278	Cold shock
F0M17_RS13105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F0M17_RS13130	COG0583	DNA-binding transcription factor activity
F0M17_RS13135	COG1024	Enoyl-CoA hydratase
F0M17_RS13140	COG0069	glutamate synthase activity
F0M17_RS13145	COG1132	(ABC) transporter
F0M17_RS13150	COG4988	ABC transporter
F0M17_RS13160	COG0135	phosphoribosylanthranilate isomerase activity
F0M17_RS13170	COG4585	Histidine kinase
F0M17_RS13175	COG2197	response regulator
F0M17_RS13180	COG4152	abc transporter atp-binding protein
F0M17_RS13190	COG0154	amidase activity
F0M17_RS13195	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F0M17_RS13205	COG0583	DNA-binding transcription factor activity
F0M17_RS13215	COG1012	belongs to the aldehyde dehydrogenase family
F0M17_RS13220	COG0583	DNA-binding transcription factor activity
F0M17_RS13225	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F0M17_RS13230	COG1090	epimerase
F0M17_RS13270	COG0561	phosphatase activity
F0M17_RS13275	COG1940	carbohydrate kinase activity
F0M17_RS13280	COG1940	carbohydrate kinase activity
F0M17_RS13285	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
F0M17_RS13365	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
F0M17_RS13390	COG0590	tRNA wobble adenosine to inosine editing
F0M17_RS13400	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
F0M17_RS13415	COG1414	Transcriptional regulator
F0M17_RS13445	COG2814	Major facilitator Superfamily
F0M17_RS13460	COG1648	precorrin-2 dehydrogenase activity
F0M17_RS13460	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
F0M17_RS13470	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F0M17_RS13480	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
F0M17_RS13485	COG0783	Belongs to the Dps family
F0M17_RS13500	COG2986	histidine ammonia-lyase
F0M17_RS13510	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
F0M17_RS13540	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F0M17_RS13545	COG1879	ABC-type sugar transport system periplasmic component
F0M17_RS13550	COG1172	Belongs to the binding-protein-dependent transport system permease family
F0M17_RS13555	COG1129	ABC transporter
F0M17_RS13575	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F0M17_RS13580	COG1121	(ABC) transporter
F0M17_RS13590	COG0010	Belongs to the arginase family
F0M17_RS13615	COG0789	Transcriptional regulator
F0M17_RS13635	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
F0M17_RS13690	COG2211	Major facilitator Superfamily
F0M17_RS13700	COG2146	nitrite reductase [NAD(P)H] activity
F0M17_RS13715	COG2188	Transcriptional regulator
F0M17_RS13720	COG2610	gluconate transmembrane transporter activity
F0M17_RS13725	COG0589	response to stress
F0M17_RS13745	COG0583	DNA-binding transcription factor activity
F0M17_RS13750	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F0M17_RS13760	COG4948	Mandelate Racemase Muconate Lactonizing
F0M17_RS13770	COG1404	Belongs to the peptidase S8 family
F0M17_RS13775	COG3384	dioxygenase
F0M17_RS13780	COG4608	Belongs to the ABC transporter superfamily
F0M17_RS13785	COG0444	Belongs to the ABC transporter superfamily
F0M17_RS13790	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F0M17_RS13795	COG0601	transmembrane transport
F0M17_RS13800	COG0747	negative chemotaxis
F0M17_RS13805	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F0M17_RS13810	COG0583	DNA-binding transcription factor activity
F0M17_RS13815	COG4948	Mandelate Racemase Muconate Lactonizing
F0M17_RS13820	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F0M17_RS13830	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
F0M17_RS13840	COG2188	Transcriptional regulator
F0M17_RS13845	COG1620	l-lactate permease
F0M17_RS13850	COG0247	lactate metabolic process
F0M17_RS13855	COG1139	Iron-sulfur cluster binding protein
F0M17_RS13860	COG1556	Lactate utilization protein
F0M17_RS13875	COG2814	Major facilitator Superfamily
F0M17_RS13890	COG1732	Glycine betaine
F0M17_RS13895	COG1174	glycine betaine transport
F0M17_RS13905	COG1174	glycine betaine transport
F0M17_RS13910	COG0179	Fumarylacetoacetate (FAA) hydrolase
F0M17_RS13920	COG0257	Belongs to the bacterial ribosomal protein bL36 family
F0M17_RS13925	COG1115	amino acid carrier protein
F0M17_RS13930	COG2301	Belongs to the HpcH HpaI aldolase family
F0M17_RS13935	COG1113	amino acid transport
F0M17_RS13960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F0M17_RS13970	COG1414	Transcriptional regulator
F0M17_RS13980	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
F0M17_RS13995	COG1028	Short-chain dehydrogenase reductase Sdr
F0M17_RS14015	COG1733	regulation of RNA biosynthetic process
F0M17_RS14035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F0M17_RS14070	COG0318	PFAM AMP-dependent synthetase and ligase
F0M17_RS14105	COG0183	Belongs to the thiolase family
F0M17_RS14110	COG0406	alpha-ribazole phosphatase activity
F0M17_RS14115	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
F0M17_RS14120	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
F0M17_RS14140	COG2186	Transcriptional regulator
F0M17_RS14150	COG1027	Aspartate ammonia-lyase
F0M17_RS14160	COG0277	FAD linked oxidase domain protein
F0M17_RS14160	COG0247	lactate metabolic process
F0M17_RS14185	COG0823	Involved in the tonB-independent uptake of proteins
F0M17_RS14185	COG1506	peptidase
F0M17_RS14215	COG0508	dehydrogenase complex catalyzes the overall conversion of
F0M17_RS14220	COG0022	dehydrogenase e1 component
F0M17_RS14230	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
F0M17_RS14235	COG1950	PFAM Membrane protein of
F0M17_RS14250	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
F0M17_RS14260	COG0277	FAD linked oxidase domain protein
F0M17_RS14320	COG1529	Aldehyde oxidase and xanthine dehydrogenase
F0M17_RS14330	COG2252	PERMEase
F0M17_RS14335	COG0590	tRNA wobble adenosine to inosine editing
F0M17_RS14345	COG2223	nitrite transmembrane transporter activity
F0M17_RS14350	COG0243	molybdopterin cofactor binding
F0M17_RS14355	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F0M17_RS14370	COG2146	nitrite reductase [NAD(P)H] activity
F0M17_RS14370	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F0M17_RS14385	COG2233	PERMEase
F0M17_RS14395	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
F0M17_RS14405	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
F0M17_RS14410	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
F0M17_RS14420	COG1802	Transcriptional regulator
F0M17_RS14435	COG0596	Alpha beta hydrolase
F0M17_RS14440	COG1012	belongs to the aldehyde dehydrogenase family
F0M17_RS14450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F0M17_RS14465	COG0318	PFAM AMP-dependent synthetase and ligase
F0M17_RS14470	COG1024	Enoyl-CoA hydratase
F0M17_RS14480	COG2197	response regulator
F0M17_RS14485	COG4585	Histidine kinase
F0M17_RS14495	COG1131	(ABC) transporter
F0M17_RS14515	COG0436	Aminotransferase
F0M17_RS14530	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F0M17_RS14535	COG0820	rRNA (adenine-C2-)-methyltransferase activity
F0M17_RS14555	COG3424	synthase
F0M17_RS14590	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F0M17_RS14595	COG2957	Belongs to the agmatine deiminase family
F0M17_RS14600	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F0M17_RS14640	COG2066	Belongs to the glutaminase family
F0M17_RS14645	COG1607	acyl-coa hydrolase
F0M17_RS14680	COG1070	Carbohydrate kinase
F0M17_RS14690	COG2814	Major facilitator Superfamily
F0M17_RS14705	COG1129	ABC transporter
F0M17_RS14725	COG2807	transmembrane transport
F0M17_RS14760	COG1937	Protein conserved in bacteria
F0M17_RS14780	COG1473	amidohydrolase
F0M17_RS14790	COG1113	amino acid transport
F0M17_RS14800	COG1289	transmembrane transporter activity
F0M17_RS14830	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
F0M17_RS14835	COG0531	amino acid
F0M17_RS14865	COG0534	Mate efflux family protein
F0M17_RS14875	COG2814	Major facilitator Superfamily
F0M17_RS14880	COG1266	CAAX protease self-immunity
F0M17_RS14925	COG2154	pterin-4-alpha-carbinolamine dehydratase
F0M17_RS14935	COG2323	membrane
F0M17_RS14945	COG1335	isochorismatase
F0M17_RS14975	COG1028	Short-chain dehydrogenase reductase Sdr
F0M17_RS14995	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
F0M17_RS15015	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
F0M17_RS15025	COG1012	belongs to the aldehyde dehydrogenase family
F0M17_RS15045	COG0415	Belongs to the DNA photolyase family
F0M17_RS15060	COG1063	alcohol dehydrogenase
F0M17_RS15075	COG0747	negative chemotaxis
F0M17_RS15085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F0M17_RS15090	COG4172	Belongs to the ABC transporter superfamily
F0M17_RS15100	COG1028	Short-chain dehydrogenase reductase Sdr
F0M17_RS15110	COG3959	Transketolase, thiamine diphosphate binding domain
F0M17_RS15115	COG3958	Transketolase
F0M17_RS15125	COG1902	pentaerythritol trinitrate reductase activity
F0M17_RS15130	COG1122	ATPase activity
F0M17_RS15145	COG1957	nucleoside hydrolase
F0M17_RS15170	COG1401	restriction endodeoxyribonuclease activity
F0M17_RS15190	COG2186	Transcriptional regulator
F0M17_RS15195	COG0531	amino acid
F0M17_RS15205	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
F0M17_RS15210	COG1012	belongs to the aldehyde dehydrogenase family
F0M17_RS15220	COG0019	diaminopimelate decarboxylase activity
F0M17_RS15230	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
F0M17_RS15235	COG1132	(ABC) transporter
F0M17_RS15240	COG1132	(ABC) transporter
F0M17_RS15245	COG5265	(ABC) transporter
F0M17_RS15255	COG0477	Major facilitator Superfamily
F0M17_RS15260	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
F0M17_RS15280	COG0693	protein deglycase activity
F0M17_RS15285	COG1802	Transcriptional regulator
F0M17_RS15300	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
F0M17_RS15310	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
F0M17_RS15325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F0M17_RS15335	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
F0M17_RS15340	COG0798	PFAM Bile acid sodium symporter
F0M17_RS15380	COG2066	Belongs to the glutaminase family
F0M17_RS15390	COG3949	Membrane
F0M17_RS15400	COG2261	transglycosylase associated protein
F0M17_RS15445	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
F0M17_RS15455	COG3177	Filamentation induced by cAMP protein fic
F0M17_RS15460	COG2855	membrane
F0M17_RS15475	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F0M17_RS15495	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
F0M17_RS15500	COG1063	alcohol dehydrogenase
F0M17_RS15505	COG0583	DNA-binding transcription factor activity
F0M17_RS15540	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
F0M17_RS15545	COG3404	Formiminotransferase-cyclodeaminase
F0M17_RS15575	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
F0M17_RS15580	COG3960	tartronate-semialdehyde synthase activity
F0M17_RS15585	COG2084	Dehydrogenase
F0M17_RS15590	COG3622	Belongs to the hyi family
F0M17_RS15595	COG1953	Uracil, thiamine, allantoin
F0M17_RS15630	COG1028	Short-chain dehydrogenase reductase Sdr
F0M17_RS15635	COG3848	Pyruvate phosphate dikinase
F0M17_RS15635	COG0574	Belongs to the PEP-utilizing enzyme family
F0M17_RS15650	COG1414	Transcriptional regulator
F0M17_RS15690	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F0M17_RS15695	COG0738	Major facilitator superfamily
F0M17_RS15710	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
F0M17_RS15755	COG2149	membrane
F0M17_RS15765	COG0477	Major facilitator Superfamily
F0M17_RS15790	COG2610	gluconate transmembrane transporter activity
F0M17_RS15795	COG3835	regulator
F0M17_RS15795	COG3835	regulator
F0M17_RS15840	COG2368	4-hydroxyphenylacetate
F0M17_RS15845	COG0477	Major facilitator Superfamily
F0M17_RS15850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F0M17_RS15855	COG0583	DNA-binding transcription factor activity
F0M17_RS15870	COG1309	transcriptional regulator
F0M17_RS15880	COG1116	anion transmembrane transporter activity
F0M17_RS15885	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F0M17_RS15900	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F0M17_RS15920	COG2267	carboxylic ester hydrolase activity
F0M17_RS15935	COG1802	Transcriptional regulator
F0M17_RS15955	COG0179	Fumarylacetoacetate (FAA) hydrolase
F0M17_RS15960	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F0M17_RS15975	COG1929	Belongs to the glycerate kinase type-1 family
F0M17_RS15985	COG0477	Major facilitator Superfamily
F0M17_RS15990	COG1028	Short-chain dehydrogenase reductase Sdr
F0M17_RS15995	COG0477	Major facilitator Superfamily
F0M17_RS16000	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F0M17_RS16005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F0M17_RS16010	COG0006	proline dipeptidase activity
F0M17_RS16025	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
F0M17_RS16035	COG0686	Belongs to the AlaDH PNT family
F0M17_RS16040	COG0659	secondary active sulfate transmembrane transporter activity
F0M17_RS16060	COG0463	Glycosyl transferase, family 2
F0M17_RS16065	COG0318	PFAM AMP-dependent synthetase and ligase
F0M17_RS16075	COG0583	DNA-binding transcription factor activity
F0M17_RS16085	COG4829	muconolactone delta-isomerase
F0M17_RS16090	COG3485	protocatechuate 3,4-dioxygenase
F0M17_RS16115	COG2814	Major facilitator Superfamily
F0M17_RS16130	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
F0M17_RS16135	COG4638	Rieske (2fe-2S)
F0M17_RS16160	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
F0M17_RS16185	COG3012	SEC-C Motif Domain Protein
F0M17_RS16195	COG0523	cobalamin synthesis protein
F0M17_RS16205	COG4115	mRNA cleavage
F0M17_RS16215	COG3257	ureidoglycine aminohydrolase activity
F0M17_RS16225	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
F0M17_RS16240	COG1053	succinate dehydrogenase
F0M17_RS16245	COG1132	(ABC) transporter
F0M17_RS16260	COG0477	Major facilitator Superfamily
F0M17_RS16275	COG0579	oxidoreductase
F0M17_RS16285	COG1309	transcriptional regulator
F0M17_RS16290	COG0667	Aldo Keto reductase
F0M17_RS16305	COG0531	amino acid
F0M17_RS16320	COG0673	inositol 2-dehydrogenase activity
F0M17_RS16330	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
F0M17_RS16340	COG2017	converts alpha-aldose to the beta-anomer
F0M17_RS16345	COG4214	carbohydrate transport
F0M17_RS16355	COG4213	ABC transporter substrate-binding protein
F0M17_RS16360	COG2160	L-arabinose isomerase activity
F0M17_RS16375	COG1609	Transcriptional regulator
F0M17_RS16425	COG2233	PERMEase
F0M17_RS16435	COG2351	hydroxyisourate hydrolase activity
F0M17_RS16465	COG0679	Auxin Efflux Carrier
F0M17_RS16470	COG1028	Short-chain dehydrogenase reductase Sdr
F0M17_RS16490	COG1846	Transcriptional regulator
F0M17_RS16520	COG0305	Participates in initiation and elongation during chromosome replication
F0M17_RS16525	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F0M17_RS16540	COG0318	PFAM AMP-dependent synthetase and ligase
F0M17_RS16560	COG2133	pyrroloquinoline quinone binding
F0M17_RS16655	COG0740	serine-type endopeptidase activity
F0M17_RS16790	COG2176	DNA-directed DNA polymerase activity
F0M17_RS16830	COG0359	binds to the 23S rRNA
F0M17_RS16835	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
F0M17_RS16845	COG0360	Binds together with S18 to 16S ribosomal RNA
F0M17_RS16865	COG1362	aminopeptidase activity
F0M17_RS16875	COG2197	response regulator
F0M17_RS16880	COG4585	Histidine kinase
F0M17_RS16915	COG2089	acid synthase
F0M17_RS16920	COG1216	Glycosyl transferase, family 2
F0M17_RS16920	COG1442	glycosyl transferase family 8
F0M17_RS16940	COG1260	myo-inositol-1-phosphate synthase
F0M17_RS16945	COG0617	tRNA 3'-terminal CCA addition
F0M17_RS16965	COG0492	ferredoxin-NADP+ reductase activity
F0M17_RS16970	COG3118	belongs to the thioredoxin family
F0M17_RS16985	COG1475	DNA binding
F0M17_RS16990	COG1192	Involved in chromosome partitioning
F0M17_RS16995	COG0357	Ribosomal RNA small subunit methyltransferase G
F0M17_RS17005	COG0706	membrane insertase activity
F0M17_RS17010	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
F0M17_RS17015	COG0594	ribonuclease P activity
F0M17_RS17020	COG0230	Belongs to the bacterial ribosomal protein bL34 family
F0M17_RS17085	COG4638	Rieske (2fe-2S)
F0M17_RS17135	COG1733	regulation of RNA biosynthetic process
F0M17_RS17150	COG1414	Transcriptional regulator
F0M17_RS17190	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
F0M17_RS17240	COG0656	L-ascorbic acid biosynthetic process
F0M17_RS17255	COG2801	Transposase and inactivated derivatives
F0M17_RS17315	COG1192	Involved in chromosome partitioning