locus-tag	class	description
JVX90_RS00120	COG2176	DNA-directed DNA polymerase activity
JVX90_RS00375	COG0739	heme binding
JVX90_RS00425	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JVX90_RS00430	COG1088	dTDP-glucose 4,6-dehydratase activity
JVX90_RS00435	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
JVX90_RS00440	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
JVX90_RS00445	COG1063	alcohol dehydrogenase
JVX90_RS00460	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JVX90_RS00475	COG1028	Short-chain dehydrogenase reductase Sdr
JVX90_RS00495	COG0351	phosphomethylpyrimidine kinase
JVX90_RS00500	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
JVX90_RS00550	COG2032	superoxide dismutase activity
JVX90_RS00560	COG1320	monovalent cation:proton antiporter activity
JVX90_RS00575	COG0651	ATP synthesis coupled electron transport
JVX90_RS00580	COG1006	Multisubunit Na H antiporter MnhC subunit
JVX90_RS00585	COG2111	Na H antiporter
JVX90_RS00585	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JVX90_RS00605	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JVX90_RS00610	COG1183	phosphatidylcholine synthase activity
JVX90_RS00615	COG0688	phosphatidylethanolamine metabolic process
JVX90_RS00625	COG1960	acyl-CoA dehydrogenase activity
JVX90_RS00630	COG1960	acyl-CoA dehydrogenase activity
JVX90_RS00635	COG0154	amidase activity
JVX90_RS00640	COG0477	Major facilitator Superfamily
JVX90_RS00645	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JVX90_RS00655	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JVX90_RS00665	COG3279	Response regulator of the LytR AlgR family
JVX90_RS00670	COG3275	phosphorelay sensor kinase activity
JVX90_RS00675	COG1785	Belongs to the alkaline phosphatase family
JVX90_RS00695	COG1473	amidohydrolase
JVX90_RS00700	COG2365	Tyrosine phosphatase family
JVX90_RS00720	COG2326	polyphosphate kinase activity
JVX90_RS00735	COG1120	ATPase activity
JVX90_RS00740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JVX90_RS00750	COG1505	serine-type exopeptidase activity
JVX90_RS00755	COG0477	Major facilitator Superfamily
JVX90_RS00775	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JVX90_RS00780	COG0833	amino acid
JVX90_RS00790	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JVX90_RS00810	COG1231	oxidoreductase activity
JVX90_RS00815	COG1309	transcriptional regulator
JVX90_RS00820	COG1960	acyl-CoA dehydrogenase activity
JVX90_RS00870	COG2224	Isocitrate lyase
JVX90_RS00885	COG2326	polyphosphate kinase activity
JVX90_RS00895	COG2733	membrane
JVX90_RS00910	COG0789	Transcriptional regulator
JVX90_RS00920	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JVX90_RS00965	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JVX90_RS00985	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
JVX90_RS00995	COG0789	Transcriptional regulator
JVX90_RS01030	COG2272	Belongs to the type-B carboxylesterase lipase family
JVX90_RS01045	COG0745	RESPONSE REGULATOR receiver
JVX90_RS01050	COG2205	protein histidine kinase activity
JVX90_RS01060	COG2132	Multicopper oxidase
JVX90_RS01090	COG0514	ATP-dependent DNA helicase (RecQ)
JVX90_RS01105	COG0667	Aldo Keto reductase
JVX90_RS01110	COG0259	pyridoxamine-phosphate oxidase activity
JVX90_RS01120	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JVX90_RS01130	COG0151	Belongs to the GarS family
JVX90_RS01145	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JVX90_RS01160	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JVX90_RS01170	COG0477	Major facilitator Superfamily
JVX90_RS01180	COG0386	Belongs to the glutathione peroxidase family
JVX90_RS01185	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JVX90_RS01190	COG0047	phosphoribosylformylglycinamidine synthase activity
JVX90_RS01195	COG1362	aminopeptidase activity
JVX90_RS01200	COG3237	CsbD-like
JVX90_RS01215	COG1733	regulation of RNA biosynthetic process
JVX90_RS01220	COG0702	epimerase
JVX90_RS01265	COG5479	isomerase activity
JVX90_RS01265	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
JVX90_RS01270	COG0657	acetylesterase activity
JVX90_RS01280	COG1028	Short-chain dehydrogenase reductase Sdr
JVX90_RS01295	COG3631	Ketosteroid isomerase-related protein
JVX90_RS01305	COG1053	succinate dehydrogenase
JVX90_RS01310	COG1053	succinate dehydrogenase
JVX90_RS01315	COG2072	flavoprotein involved in K transport
JVX90_RS01330	COG0346	lactoylglutathione lyase activity
JVX90_RS01345	COG1309	transcriptional regulator
JVX90_RS01350	COG1960	acyl-CoA dehydrogenase activity
JVX90_RS01355	COG1960	acyl-CoA dehydrogenase activity
JVX90_RS01360	COG2030	dehydratase
JVX90_RS01385	COG0488	(ABC) transporter
JVX90_RS01410	COG0477	Major facilitator Superfamily
JVX90_RS01420	COG2030	dehydratase
JVX90_RS01425	COG1053	succinate dehydrogenase
JVX90_RS01445	COG1053	succinate dehydrogenase
JVX90_RS01460	COG1960	acyl-CoA dehydrogenase activity
JVX90_RS01465	COG0346	lactoylglutathione lyase activity
JVX90_RS01470	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JVX90_RS01500	COG1960	acyl-CoA dehydrogenase activity
JVX90_RS01505	COG1960	acyl-CoA dehydrogenase activity
JVX90_RS01510	COG1024	Enoyl-CoA hydratase
JVX90_RS01530	COG0175	sulfate reduction
JVX90_RS01545	COG0464	growth
JVX90_RS01550	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JVX90_RS01595	COG0613	PHP domain protein
JVX90_RS01630	COG1271	oxidase subunit
JVX90_RS01635	COG1294	oxidase, subunit
JVX90_RS01640	COG4988	ABC transporter
JVX90_RS01645	COG4988	ABC transporter
JVX90_RS01650	COG1528	Iron-storage protein
JVX90_RS01655	COG4044	May play a role in the intracellular transport of hydrophobic ligands
JVX90_RS01665	COG2897	thiosulfate sulfurtransferase activity
JVX90_RS01675	COG0745	RESPONSE REGULATOR receiver
JVX90_RS01680	COG0456	acetyltransferase
JVX90_RS01680	COG0454	-acetyltransferase
JVX90_RS01695	COG0581	inorganic phosphate transmembrane transporter activity
JVX90_RS01700	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JVX90_RS01790	COG1674	ftsk spoiiie
JVX90_RS01830	COG3209	COG3209 Rhs family protein
JVX90_RS01880	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JVX90_RS01880	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JVX90_RS01905	COG2409	Drug exporters of the RND superfamily
JVX90_RS01920	COG0154	amidase activity
JVX90_RS01930	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JVX90_RS01965	COG1733	regulation of RNA biosynthetic process
JVX90_RS01975	COG1309	transcriptional regulator
JVX90_RS01985	COG0494	nUDIX hydrolase
JVX90_RS01990	COG2353	YceI-like domain
JVX90_RS02015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JVX90_RS02020	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JVX90_RS02025	COG1120	ATPase activity
JVX90_RS02065	COG1278	Cold shock
JVX90_RS02075	COG2814	Major facilitator Superfamily
JVX90_RS02090	COG0671	phosphoesterase, PA-phosphatase related
JVX90_RS02100	COG2252	PERMEase
JVX90_RS02125	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JVX90_RS02130	COG2364	Membrane
JVX90_RS02135	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JVX90_RS02150	COG2814	Major facilitator Superfamily
JVX90_RS02170	COG1984	allophanate hydrolase subunit 2
JVX90_RS02185	COG0545	Peptidyl-prolyl cis-trans isomerase
JVX90_RS02210	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JVX90_RS02275	COG1218	3'(2'),5'-bisphosphate nucleotidase
JVX90_RS02280	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JVX90_RS02295	COG0166	Belongs to the GPI family
JVX90_RS02315	COG0739	heme binding
JVX90_RS02320	COG0045	succinate-CoA ligase (ADP-forming) activity
JVX90_RS02360	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JVX90_RS02370	COG1960	acyl-CoA dehydrogenase activity
JVX90_RS02385	COG0318	PFAM AMP-dependent synthetase and ligase
JVX90_RS02390	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JVX90_RS02425	COG1131	(ABC) transporter
JVX90_RS02435	COG3012	SEC-C Motif Domain Protein
JVX90_RS02455	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JVX90_RS02460	COG4521	taurine ABC transporter
JVX90_RS02470	COG2175	clavaminate synthase activity
JVX90_RS02475	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
JVX90_RS02485	COG1305	Transglutaminase-like
JVX90_RS02520	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JVX90_RS02525	COG1012	belongs to the aldehyde dehydrogenase family
JVX90_RS02535	COG4221	oxidoreductase activity
JVX90_RS02555	COG2205	protein histidine kinase activity
JVX90_RS02560	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JVX90_RS02580	COG1970	mechanosensitive ion channel activity
JVX90_RS02590	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JVX90_RS02595	COG1115	amino acid carrier protein
JVX90_RS02610	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JVX90_RS02615	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JVX90_RS02625	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JVX90_RS02715	COG2814	Major facilitator Superfamily
JVX90_RS02760	COG0384	phenazine biosynthesis protein PhzF
JVX90_RS02765	COG0084	hydrolase, TatD family'
JVX90_RS02770	COG3583	domain protein
JVX90_RS02775	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JVX90_RS02780	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JVX90_RS02790	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JVX90_RS02805	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JVX90_RS02850	COG1028	Short-chain dehydrogenase reductase Sdr
JVX90_RS02855	COG2072	flavoprotein involved in K transport
JVX90_RS02880	COG2072	flavoprotein involved in K transport
JVX90_RS02885	COG4221	oxidoreductase activity
JVX90_RS02890	COG0488	(ABC) transporter
JVX90_RS02895	COG1024	Enoyl-CoA hydratase
JVX90_RS02905	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
JVX90_RS02940	COG0193	aminoacyl-tRNA hydrolase activity
JVX90_RS02945	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JVX90_RS02950	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
JVX90_RS02955	COG1393	Belongs to the ArsC family
JVX90_RS02965	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JVX90_RS02995	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JVX90_RS03015	COG1073	alpha beta
JVX90_RS03055	COG1113	amino acid transport
JVX90_RS03070	COG2847	Copper chaperone PCu(A)C
JVX90_RS03090	COG0488	(ABC) transporter
JVX90_RS03115	COG3956	TIGRFAM MazG family protein
JVX90_RS03140	COG2837	iron assimilation
JVX90_RS03150	COG0672	)-iron permease
JVX90_RS03165	COG1309	transcriptional regulator
JVX90_RS03175	COG0148	phosphopyruvate hydratase activity
JVX90_RS03260	COG1309	transcriptional regulator
JVX90_RS03310	COG2267	carboxylic ester hydrolase activity
JVX90_RS03315	COG4221	oxidoreductase activity
JVX90_RS03350	COG2409	Drug exporters of the RND superfamily
JVX90_RS03375	COG0135	phosphoribosylanthranilate isomerase activity
JVX90_RS03380	COG1263	PTS System
JVX90_RS03380	COG2190	(PTS) system
JVX90_RS03380	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JVX90_RS03390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JVX90_RS03395	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JVX90_RS03420	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
JVX90_RS03420	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
JVX90_RS03440	COG2814	Major facilitator Superfamily
JVX90_RS03455	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
JVX90_RS03465	COG2365	Tyrosine phosphatase family
JVX90_RS03490	COG1984	allophanate hydrolase subunit 2
JVX90_RS03515	COG1250	3-hydroxyacyl-CoA dehydrogenase
JVX90_RS03525	COG0477	Major facilitator Superfamily
JVX90_RS03550	COG2409	Drug exporters of the RND superfamily
JVX90_RS03575	COG2814	Major facilitator Superfamily
JVX90_RS03600	COG0183	Belongs to the thiolase family
JVX90_RS03645	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JVX90_RS03655	COG0318	PFAM AMP-dependent synthetase and ligase
JVX90_RS03670	COG1331	Highly conserved protein containing a thioredoxin domain
JVX90_RS03675	COG3573	Dehydrogenase
JVX90_RS03695	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JVX90_RS03725	COG1072	(Pantothenic acid kinase))
JVX90_RS03735	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JVX90_RS03755	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
JVX90_RS03785	COG2197	response regulator
JVX90_RS03790	COG4585	Histidine kinase
JVX90_RS03800	COG1136	(ABC) transporter
JVX90_RS03805	COG1494	fructose-1,6-bisphosphatase
JVX90_RS03820	COG1570	exodeoxyribonuclease VII activity
JVX90_RS03830	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JVX90_RS03840	COG1053	succinate dehydrogenase
JVX90_RS03845	COG1404	Belongs to the peptidase S8 family
JVX90_RS03855	COG1674	ftsk spoiiie
JVX90_RS03870	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JVX90_RS03880	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JVX90_RS03900	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JVX90_RS03910	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JVX90_RS03925	COG0456	acetyltransferase
JVX90_RS03925	COG1214	PFAM Peptidase M22, glycoprotease
JVX90_RS03930	COG0456	acetyltransferase
JVX90_RS03935	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JVX90_RS03940	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JVX90_RS03975	COG0516	GMP reductase activity
JVX90_RS03995	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JVX90_RS04000	COG1122	ATPase activity
JVX90_RS04005	COG1268	BioY protein
JVX90_RS04015	COG1595	DNA-templated transcription, initiation
JVX90_RS04060	COG0210	DNA helicase
JVX90_RS04065	COG1201	RNA secondary structure unwinding
JVX90_RS04085	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JVX90_RS04125	COG2197	response regulator
JVX90_RS04130	COG0515	serine threonine protein kinase
JVX90_RS04130	COG2815	serine threonine protein kinase
JVX90_RS04140	COG0390	transport system, permease component
JVX90_RS04165	COG0587	DNA-directed DNA polymerase activity
JVX90_RS04175	COG0372	Belongs to the citrate synthase family
JVX90_RS04185	COG1872	DUF167
JVX90_RS04200	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JVX90_RS04270	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JVX90_RS04280	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JVX90_RS04285	COG2873	o-acetylhomoserine
JVX90_RS04290	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
JVX90_RS04300	COG2814	Major facilitator Superfamily
JVX90_RS04315	COG0180	Tryptophanyl-tRNA synthetase
JVX90_RS04320	COG1295	ribonuclease BN
JVX90_RS04330	COG1686	Belongs to the peptidase S11 family
JVX90_RS04335	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JVX90_RS04340	COG1053	succinate dehydrogenase
JVX90_RS04350	COG2009	succinate dehydrogenase
JVX90_RS04385	COG1595	DNA-templated transcription, initiation
JVX90_RS04405	COG0791	NLP P60 protein
JVX90_RS04410	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JVX90_RS04425	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JVX90_RS04440	COG1473	amidohydrolase
JVX90_RS04440	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
JVX90_RS04480	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JVX90_RS04505	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JVX90_RS04510	COG1201	RNA secondary structure unwinding
JVX90_RS04535	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JVX90_RS04540	COG1960	acyl-CoA dehydrogenase activity
JVX90_RS04570	COG2072	flavoprotein involved in K transport
JVX90_RS04580	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JVX90_RS04585	COG1012	belongs to the aldehyde dehydrogenase family
JVX90_RS04590	COG3835	regulator
JVX90_RS04595	COG1396	sequence-specific DNA binding
JVX90_RS04595	COG3800	Transcriptional regulator
JVX90_RS04605	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
JVX90_RS04625	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JVX90_RS04630	COG0668	transmembrane transport
JVX90_RS04645	COG4770	biotin carboxylase activity
JVX90_RS04670	COG0424	maF-like protein
JVX90_RS04680	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JVX90_RS04700	COG0745	RESPONSE REGULATOR receiver
JVX90_RS04705	COG4191	Histidine kinase
JVX90_RS04720	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JVX90_RS04760	COG2203	Gaf domain
JVX90_RS04760	COG3706	GGDEF domain
JVX90_RS04760	COG4251	negative regulation of phosphorylation
JVX90_RS04760	COG5001	Diguanylate cyclase
JVX90_RS04765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JVX90_RS04775	COG1316	TRANSCRIPTIONal
JVX90_RS04795	COG4122	O-methyltransferase activity
JVX90_RS04810	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JVX90_RS04815	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JVX90_RS04830	COG1132	(ABC) transporter
JVX90_RS04880	COG0598	Magnesium transport protein CorA
JVX90_RS04885	COG2095	MarC family integral membrane protein
JVX90_RS04910	COG0508	dehydrogenase complex catalyzes the overall conversion of
JVX90_RS04910	COG0567	Dehydrogenase, E1 component
JVX90_RS04915	COG1132	(ABC) transporter
JVX90_RS04970	COG1252	NADH dehydrogenase
JVX90_RS04975	COG1595	DNA-templated transcription, initiation
JVX90_RS04980	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JVX90_RS05005	COG0018	arginyl-trna synthetase
JVX90_RS05010	COG0019	diaminopimelate decarboxylase activity
JVX90_RS05015	COG0460	homoserine dehydrogenase
JVX90_RS05020	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JVX90_RS05040	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JVX90_RS05045	COG0254	rRNA binding
JVX90_RS05050	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JVX90_RS05055	COG2890	protein-(glutamine-N5) methyltransferase activity
JVX90_RS05085	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JVX90_RS05100	COG0356	it plays a direct role in the translocation of protons across the membrane
JVX90_RS05105	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JVX90_RS05110	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JVX90_RS05120	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JVX90_RS05130	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JVX90_RS05170	COG1454	alcohol dehydrogenase
JVX90_RS05175	COG4585	Histidine kinase
JVX90_RS05180	COG2197	response regulator
JVX90_RS05210	COG2957	Belongs to the agmatine deiminase family
JVX90_RS05255	COG0318	PFAM AMP-dependent synthetase and ligase
JVX90_RS05270	COG1309	transcriptional regulator
JVX90_RS05290	COG0183	Belongs to the thiolase family
JVX90_RS05295	COG2409	Drug exporters of the RND superfamily
JVX90_RS05305	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JVX90_RS05315	COG1335	isochorismatase
JVX90_RS05320	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JVX90_RS05325	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
JVX90_RS05335	COG3191	aminopeptidase activity
JVX90_RS05345	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JVX90_RS05350	COG1234	tRNA 3'-trailer cleavage
JVX90_RS05375	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
JVX90_RS05380	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JVX90_RS05400	COG2205	protein histidine kinase activity
JVX90_RS05405	COG0745	RESPONSE REGULATOR receiver
JVX90_RS05425	COG1132	(ABC) transporter
JVX90_RS05440	COG1280	lysine exporter protein (LysE YggA)
JVX90_RS05470	COG2890	protein-(glutamine-N5) methyltransferase activity
JVX90_RS05540	COG2030	dehydratase
JVX90_RS05545	COG0736	holo-[acyl-carrier-protein] synthase activity
JVX90_RS05575	COG1376	ErfK ybiS ycfS ynhG family protein
JVX90_RS05580	COG1960	acyl-CoA dehydrogenase activity
JVX90_RS05585	COG0076	glutamate decarboxylase activity
JVX90_RS05610	COG0560	Phosphoserine phosphatase
JVX90_RS05610	COG3830	Belongs to the UPF0237 family
JVX90_RS05620	COG0351	phosphomethylpyrimidine kinase
JVX90_RS05650	COG3340	Belongs to the peptidase S51 family
JVX90_RS05655	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JVX90_RS05660	COG1953	Uracil, thiamine, allantoin
JVX90_RS05670	COG3257	ureidoglycine aminohydrolase activity
JVX90_RS05690	COG2154	pterin-4-alpha-carbinolamine dehydratase
JVX90_RS05730	COG0713	ATP synthesis coupled electron transport
JVX90_RS05740	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JVX90_RS05745	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
JVX90_RS05750	COG1034	ATP synthesis coupled electron transport
JVX90_RS05770	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JVX90_RS05775	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JVX90_RS05795	COG1063	alcohol dehydrogenase
JVX90_RS05815	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
JVX90_RS05820	COG0300	oxidoreductase activity
JVX90_RS05825	COG0446	pyridine nucleotide-disulphide oxidoreductase
JVX90_RS05825	COG1902	pentaerythritol trinitrate reductase activity
JVX90_RS05845	COG2223	nitrite transmembrane transporter activity
JVX90_RS05860	COG2146	nitrite reductase [NAD(P)H] activity
JVX90_RS05860	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JVX90_RS05865	COG2146	nitrite reductase [NAD(P)H] activity
JVX90_RS05865	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JVX90_RS05870	COG0243	molybdopterin cofactor binding
JVX90_RS05875	COG0183	Belongs to the thiolase family
JVX90_RS05880	COG1024	Enoyl-CoA hydratase
JVX90_RS05890	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JVX90_RS05895	COG2261	transglycosylase associated protein
JVX90_RS05915	COG3336	cytochrome c oxidase
JVX90_RS05940	COG2902	Dehydrogenase
JVX90_RS05955	COG0366	Alpha amylase catalytic
JVX90_RS05970	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
JVX90_RS05975	COG0318	PFAM AMP-dependent synthetase and ligase
JVX90_RS05985	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JVX90_RS05990	COG0501	Belongs to the peptidase M48B family
JVX90_RS06010	COG1376	ErfK ybiS ycfS ynhG family protein
JVX90_RS06020	COG3135	benzoate transporter
JVX90_RS06040	COG0544	peptidyl-prolyl cis-trans isomerase activity
JVX90_RS06045	COG0740	serine-type endopeptidase activity
JVX90_RS06050	COG0740	serine-type endopeptidase activity
JVX90_RS06065	COG0746	molybdenum cofactor guanylyltransferase activity
JVX90_RS06070	COG0525	valine-tRNA ligase activity
JVX90_RS06075	COG0285	dihydrofolate synthase activity
JVX90_RS06090	COG0105	UTP biosynthetic process
JVX90_RS06095	COG1530	ribonuclease E activity
JVX90_RS06110	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JVX90_RS06120	COG1917	Cupin 2, conserved barrel domain protein
JVX90_RS06130	COG0456	acetyltransferase
JVX90_RS06140	COG0742	ribosomal rna small subunit methyltransferase
JVX90_RS06160	COG0571	ribonuclease III activity
JVX90_RS06165	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JVX90_RS06185	COG1254	Belongs to the acylphosphatase family
JVX90_RS06200	COG1309	transcriptional regulator
JVX90_RS06205	COG1960	acyl-CoA dehydrogenase activity
JVX90_RS06225	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
JVX90_RS06245	COG0228	four-way junction DNA binding
JVX90_RS06255	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JVX90_RS06260	COG0336	Belongs to the RNA methyltransferase TrmD family
JVX90_RS06290	COG0792	nuclease activity
JVX90_RS06330	COG0052	Belongs to the universal ribosomal protein uS2 family
JVX90_RS06335	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JVX90_RS06340	COG0528	UMP kinase activity
JVX90_RS06360	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JVX90_RS06370	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
JVX90_RS06375	COG0750	zinc metalloprotease
JVX90_RS06400	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
JVX90_RS06405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JVX90_RS06420	COG1492	cobalamin metabolic process
JVX90_RS06425	COG0596	Alpha beta hydrolase
JVX90_RS06450	COG0579	oxidoreductase
JVX90_RS06490	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JVX90_RS06490	COG1648	precorrin-2 dehydrogenase activity
JVX90_RS06500	COG3022	response to hydroperoxide
JVX90_RS06505	COG0442	prolyl-tRNA aminoacylation
JVX90_RS06520	COG0779	Required for maturation of 30S ribosomal subunits
JVX90_RS06535	COG0481	GTPase activity
JVX90_RS06535	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JVX90_RS06540	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JVX90_RS06545	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JVX90_RS06550	COG0534	Mate efflux family protein
JVX90_RS06570	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
JVX90_RS06580	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JVX90_RS06600	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JVX90_RS06615	COG2197	response regulator
JVX90_RS06645	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JVX90_RS06675	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JVX90_RS06680	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JVX90_RS06690	COG2365	Tyrosine phosphatase family
JVX90_RS06705	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JVX90_RS06710	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JVX90_RS06740	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
JVX90_RS06750	COG1396	sequence-specific DNA binding
JVX90_RS06755	COG1842	Phage shock protein A
JVX90_RS06770	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JVX90_RS06780	COG0765	amino acid transport
JVX90_RS06785	COG0765	amino acid transport
JVX90_RS06790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JVX90_RS06795	COG1126	abc transporter atp-binding protein
JVX90_RS06800	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JVX90_RS06810	COG1196	nuclear chromosome segregation
JVX90_RS06820	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JVX90_RS06825	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JVX90_RS06830	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JVX90_RS06840	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JVX90_RS06840	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JVX90_RS06855	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JVX90_RS06865	COG1388	LysM domain
JVX90_RS06875	COG1643	Atp-dependent helicase
JVX90_RS06885	COG1660	Displays ATPase and GTPase activities
JVX90_RS06890	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JVX90_RS06900	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JVX90_RS06905	COG0450	alkyl hydroperoxide reductase
JVX90_RS06940	COG0123	including yeast histone deacetylase and acetoin utilization protein
JVX90_RS06965	COG0024	Methionine aminopeptidase
JVX90_RS06995	COG1309	transcriptional regulator
JVX90_RS07000	COG1028	Short-chain dehydrogenase reductase Sdr
JVX90_RS07005	COG1028	Short-chain dehydrogenase reductase Sdr
JVX90_RS07015	COG1960	acyl-CoA dehydrogenase activity
JVX90_RS07020	COG1960	acyl-CoA dehydrogenase activity
JVX90_RS07025	COG0318	PFAM AMP-dependent synthetase and ligase
JVX90_RS07045	COG0439	Biotin carboxylase
JVX90_RS07060	COG0483	inositol monophosphate 1-phosphatase activity
JVX90_RS07080	COG0756	dUTP diphosphatase activity
JVX90_RS07105	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JVX90_RS07105	COG1017	nitric oxide dioxygenase activity
JVX90_RS07115	COG0569	domain protein
JVX90_RS07120	COG0531	amino acid
JVX90_RS07125	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JVX90_RS07130	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JVX90_RS07135	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
JVX90_RS07145	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JVX90_RS07165	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JVX90_RS07275	COG1051	belongs to the nudix hydrolase family
JVX90_RS07280	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JVX90_RS07290	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JVX90_RS07295	COG1560	Kdo2-lipid A biosynthetic process
JVX90_RS07300	COG0438	transferase activity, transferring glycosyl groups
JVX90_RS07310	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
JVX90_RS07330	COG0631	protein serine/threonine phosphatase activity
JVX90_RS07350	COG1946	Acyl-CoA thioesterase
JVX90_RS07355	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
JVX90_RS07365	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
JVX90_RS07370	COG0632	four-way junction helicase activity
JVX90_RS07375	COG2255	four-way junction helicase activity
JVX90_RS07390	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JVX90_RS07395	COG0747	negative chemotaxis
JVX90_RS07400	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JVX90_RS07405	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JVX90_RS07420	COG0124	histidyl-tRNA synthetase
JVX90_RS07435	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JVX90_RS07450	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JVX90_RS07455	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JVX90_RS07465	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JVX90_RS07480	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JVX90_RS07485	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JVX90_RS07495	COG0006	proline dipeptidase activity
JVX90_RS07500	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JVX90_RS07505	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JVX90_RS07510	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JVX90_RS07515	COG0540	Belongs to the ATCase OTCase family
JVX90_RS07560	COG1758	RNA polymerase activity
JVX90_RS07570	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JVX90_RS07580	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JVX90_RS07610	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JVX90_RS07610	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JVX90_RS07625	COG0322	excinuclease ABC activity
JVX90_RS07630	COG1660	Displays ATPase and GTPase activities
JVX90_RS07635	COG0391	Required for morphogenesis under gluconeogenic growth conditions
JVX90_RS07645	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JVX90_RS07650	COG0126	phosphoglycerate kinase activity
JVX90_RS07655	COG0149	triose-phosphate isomerase activity
JVX90_RS07670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JVX90_RS07675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JVX90_RS07680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JVX90_RS07700	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
JVX90_RS07720	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JVX90_RS07730	COG0109	protoheme IX farnesyltransferase activity
JVX90_RS07755	COG1612	heme a metabolic process
JVX90_RS07790	COG0396	ATPase activity
JVX90_RS07800	COG0822	iron-sulfur transferase activity
JVX90_RS07805	COG2151	metal-sulfur cluster biosynthetic enzyme
JVX90_RS07810	COG0406	alpha-ribazole phosphatase activity
JVX90_RS07830	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JVX90_RS07845	COG1028	Short-chain dehydrogenase reductase Sdr
JVX90_RS07855	COG0488	(ABC) transporter
JVX90_RS07875	COG2072	flavoprotein involved in K transport
JVX90_RS07905	COG1309	transcriptional regulator
JVX90_RS07910	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JVX90_RS07920	COG3883	PFAM NLP P60 protein
JVX90_RS07920	COG0791	NLP P60 protein
JVX90_RS07925	COG0714	Associated with various cellular activities
JVX90_RS07945	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JVX90_RS07950	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JVX90_RS07980	COG0398	Pfam SNARE associated Golgi protein
JVX90_RS08025	COG2186	Transcriptional regulator
JVX90_RS08045	COG0604	alcohol dehydrogenase
JVX90_RS08060	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JVX90_RS08080	COG1968	undecaprenyl-diphosphatase activity
JVX90_RS08100	COG0215	cysteine-tRNA ligase activity
JVX90_RS08115	COG0646	methionine synthase
JVX90_RS08115	COG1410	methionine synthase
JVX90_RS08135	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JVX90_RS08150	COG1222	aaa ATPase
JVX90_RS08155	COG0842	Transport permease protein
JVX90_RS08155	COG1716	ATPase activity
JVX90_RS08155	COG1131	(ABC) transporter
JVX90_RS08170	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
JVX90_RS08175	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
JVX90_RS08190	COG2378	regulation of single-species biofilm formation
JVX90_RS08205	COG4581	dead DEAH box helicase
JVX90_RS08280	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JVX90_RS08325	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JVX90_RS08330	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
JVX90_RS08345	COG0671	phosphoesterase, PA-phosphatase related
JVX90_RS08355	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JVX90_RS08360	COG2814	Major facilitator Superfamily
JVX90_RS08380	COG1120	ATPase activity
JVX90_RS08385	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JVX90_RS08390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JVX90_RS08395	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JVX90_RS08405	COG1174	glycine betaine transport
JVX90_RS08415	COG1174	glycine betaine transport
JVX90_RS08420	COG1732	Glycine betaine
JVX90_RS08425	COG1231	oxidoreductase activity
JVX90_RS08430	COG1231	oxidoreductase activity
JVX90_RS08450	COG2175	clavaminate synthase activity
JVX90_RS08455	COG3246	L-lysine catabolic process to acetate
JVX90_RS08460	COG2814	Major facilitator Superfamily
JVX90_RS08470	COG0778	Nitroreductase
JVX90_RS08490	COG0183	Belongs to the thiolase family
JVX90_RS08510	COG1028	Short-chain dehydrogenase reductase Sdr
JVX90_RS08515	COG1960	acyl-CoA dehydrogenase activity
JVX90_RS08535	COG1902	pentaerythritol trinitrate reductase activity
JVX90_RS08555	COG1024	Enoyl-CoA hydratase
JVX90_RS08630	COG0640	Transcriptional regulator
JVX90_RS08635	COG0798	PFAM Bile acid sodium symporter
JVX90_RS08640	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JVX90_RS08700	COG0697	spore germination
JVX90_RS08705	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JVX90_RS08710	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
JVX90_RS08715	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JVX90_RS08730	COG0657	acetylesterase activity
JVX90_RS08745	COG1902	pentaerythritol trinitrate reductase activity
JVX90_RS08755	COG1280	lysine exporter protein (LysE YggA)
JVX90_RS08765	COG2072	flavoprotein involved in K transport
JVX90_RS08780	COG0657	acetylesterase activity
JVX90_RS08805	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JVX90_RS08860	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JVX90_RS08870	COG1074	ATP-dependent DNA helicase activity
JVX90_RS08875	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
JVX90_RS08890	COG1252	NADH dehydrogenase
JVX90_RS08895	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JVX90_RS08920	COG1253	flavin adenine dinucleotide binding
JVX90_RS08965	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JVX90_RS08970	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JVX90_RS08980	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JVX90_RS08980	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JVX90_RS09025	COG0653	protein targeting
JVX90_RS09035	COG2326	polyphosphate kinase activity
JVX90_RS09070	COG2814	Major facilitator Superfamily
JVX90_RS09080	COG1119	ATPase activity
JVX90_RS09090	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JVX90_RS09105	COG0435	Glutathione S-transferase
JVX90_RS09120	COG2188	Transcriptional regulator
JVX90_RS09150	COG1024	Enoyl-CoA hydratase
JVX90_RS09160	COG0583	DNA-binding transcription factor activity
JVX90_RS09170	COG0243	molybdopterin cofactor binding
JVX90_RS09175	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JVX90_RS09205	COG0303	'Molybdopterin
JVX90_RS09210	COG0315	cyclic pyranopterin monophosphate synthase activity
JVX90_RS09215	COG0746	molybdenum cofactor guanylyltransferase activity
JVX90_RS09230	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JVX90_RS09240	COG0521	Mo-molybdopterin cofactor biosynthetic process
JVX90_RS09240	COG0315	cyclic pyranopterin monophosphate synthase activity
JVX90_RS09245	COG0765	amino acid transport
JVX90_RS09250	COG1126	abc transporter atp-binding protein
JVX90_RS09270	COG1132	(ABC) transporter
JVX90_RS09275	COG1132	(ABC) transporter
JVX90_RS09285	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
JVX90_RS09290	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JVX90_RS09295	COG1535	isochorismatase
JVX90_RS09295	COG3433	isochorismatase activity
JVX90_RS09300	COG1021	2,3-dihydroxybenzoate-AMP ligase
JVX90_RS09305	COG3433	isochorismatase activity
JVX90_RS09305	COG1535	isochorismatase
JVX90_RS09310	COG1793	dna ligase
JVX90_RS09420	COG1160	GTP binding
JVX90_RS09425	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JVX90_RS09435	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JVX90_RS09470	COG0494	nUDIX hydrolase
JVX90_RS09495	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JVX90_RS09510	COG0647	UMP catabolic process
JVX90_RS09530	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JVX90_RS09535	COG2835	tetraacyldisaccharide 4'-kinase activity
JVX90_RS09545	COG0165	Argininosuccinate lyase
JVX90_RS09550	COG1438	arginine binding
JVX90_RS09555	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JVX90_RS09560	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JVX90_RS09570	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JVX90_RS09575	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JVX90_RS09580	COG1408	metallophosphoesterase
JVX90_RS09585	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JVX90_RS09585	COG0072	phenylalanine-tRNA ligase activity
JVX90_RS09590	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JVX90_RS09605	COG1120	ATPase activity
JVX90_RS09610	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JVX90_RS09615	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JVX90_RS09660	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JVX90_RS09675	COG3973	AAA domain
JVX90_RS09675	COG3973	AAA domain
JVX90_RS09690	COG0723	plastoquinol--plastocyanin reductase activity
JVX90_RS09715	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JVX90_RS09740	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JVX90_RS09740	COG0237	dephospho-CoA kinase activity
JVX90_RS09745	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JVX90_RS09750	COG4569	acetaldehyde dehydrogenase (acetylating) activity
JVX90_RS09755	COG3971	2-oxopent-4-enoate hydratase activity
JVX90_RS09765	COG0477	Major facilitator Superfamily
JVX90_RS09775	COG4101	3-hydroxyanthranilate 3,4-dioxygenase activity
JVX90_RS09800	COG0583	DNA-binding transcription factor activity
JVX90_RS09805	COG0318	PFAM AMP-dependent synthetase and ligase
JVX90_RS09835	COG0076	glutamate decarboxylase activity
JVX90_RS09855	COG2226	methyltransferase
JVX90_RS09865	COG1126	abc transporter atp-binding protein
JVX90_RS09870	COG0765	amino acid transport
JVX90_RS09880	COG0473	3-isopropylmalate dehydrogenase activity
JVX90_RS09915	COG3142	Participates in the control of copper homeostasis
JVX90_RS09935	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JVX90_RS09975	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JVX90_RS09990	COG0107	imidazoleglycerol-phosphate synthase activity
JVX90_RS09995	COG0483	inositol monophosphate 1-phosphatase activity
JVX90_RS10010	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JVX90_RS10020	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JVX90_RS10025	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JVX90_RS10065	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
JVX90_RS10070	COG0156	8-amino-7-oxononanoate synthase activity
JVX90_RS10075	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JVX90_RS10125	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JVX90_RS10130	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JVX90_RS10170	COG0252	asparaginase activity
JVX90_RS10190	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JVX90_RS10210	COG1799	cell septum assembly
JVX90_RS10215	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JVX90_RS10220	COG1496	oxidoreductase activity
JVX90_RS10225	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JVX90_RS10230	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JVX90_RS10235	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JVX90_RS10240	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JVX90_RS10250	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JVX90_RS10255	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JVX90_RS10265	COG0768	penicillin binding
JVX90_RS10310	COG0142	geranyltranstransferase activity
JVX90_RS10335	COG0183	Belongs to the thiolase family
JVX90_RS10350	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
JVX90_RS10370	COG1940	carbohydrate kinase activity
JVX90_RS10400	COG0438	transferase activity, transferring glycosyl groups
JVX90_RS10415	COG0791	NLP P60 protein
JVX90_RS10445	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JVX90_RS10455	COG1845	cytochrome c oxidase, subunit III
JVX90_RS10490	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JVX90_RS10500	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JVX90_RS10520	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
JVX90_RS10525	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
JVX90_RS10535	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JVX90_RS10540	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JVX90_RS10545	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JVX90_RS10550	COG0508	dehydrogenase complex catalyzes the overall conversion of
JVX90_RS10560	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JVX90_RS10600	COG0174	glutamine synthetase
JVX90_RS10615	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
JVX90_RS10640	COG0318	PFAM AMP-dependent synthetase and ligase
JVX90_RS10650	COG0318	PFAM AMP-dependent synthetase and ligase
JVX90_RS10665	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
JVX90_RS10670	COG0174	glutamine synthetase
JVX90_RS10675	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JVX90_RS10685	COG5607	PFAM CHAD domain containing protein
JVX90_RS10685	COG3025	triphosphatase activity
JVX90_RS10690	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
JVX90_RS10735	COG1764	response to oxidative stress
JVX90_RS10740	COG1846	Transcriptional regulator
JVX90_RS10745	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
JVX90_RS10785	COG1278	Cold shock
JVX90_RS10790	COG1120	ATPase activity
JVX90_RS10795	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JVX90_RS10800	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JVX90_RS10805	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JVX90_RS10815	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
JVX90_RS10850	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
JVX90_RS10865	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JVX90_RS10870	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JVX90_RS10905	COG0318	PFAM AMP-dependent synthetase and ligase
JVX90_RS10910	COG1024	Enoyl-CoA hydratase
JVX90_RS10915	COG1309	transcriptional regulator
JVX90_RS10925	COG1960	acyl-CoA dehydrogenase activity
JVX90_RS10930	COG1802	Transcriptional regulator
JVX90_RS10950	COG1937	Protein conserved in bacteria
JVX90_RS10955	COG1309	transcriptional regulator
JVX90_RS10965	COG0492	ferredoxin-NADP+ reductase activity
JVX90_RS10975	COG0477	Major facilitator Superfamily
JVX90_RS10985	COG1136	(ABC) transporter
JVX90_RS10985	COG0577	efflux transmembrane transporter activity
JVX90_RS10990	COG2197	response regulator
JVX90_RS11010	COG1297	OPT oligopeptide transporter protein
JVX90_RS11020	COG3422	double-strand break repair
JVX90_RS11030	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JVX90_RS11035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JVX90_RS11045	COG4592	Periplasmic binding protein
JVX90_RS11060	COG0596	Alpha beta hydrolase
JVX90_RS11070	COG0277	FAD linked oxidase domain protein
JVX90_RS11085	COG4942	peptidase
JVX90_RS11120	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JVX90_RS11140	COG1278	Cold shock
JVX90_RS11145	COG4552	Acetyltransferase involved in intracellular survival and related
JVX90_RS11165	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
JVX90_RS11170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JVX90_RS11190	COG0596	Alpha beta hydrolase
JVX90_RS11220	COG0423	glycine-tRNA ligase activity
JVX90_RS11240	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JVX90_RS11245	COG1381	Involved in DNA repair and RecF pathway recombination
JVX90_RS11250	COG2267	carboxylic ester hydrolase activity
JVX90_RS11270	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JVX90_RS11290	COG0484	heat shock protein binding
JVX90_RS11350	COG0657	acetylesterase activity
JVX90_RS11360	COG3842	ATPase activity
JVX90_RS11365	COG4208	sulfate ABC transporter
JVX90_RS11370	COG4208	sulfate ABC transporter
JVX90_RS11375	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
JVX90_RS11385	COG0339	signal peptide processing
JVX90_RS11390	COG0481	GTPase activity
JVX90_RS11470	COG2755	lipolytic protein G-D-S-L family
JVX90_RS11475	COG0406	alpha-ribazole phosphatase activity
JVX90_RS11485	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JVX90_RS11495	COG0542	response to heat
JVX90_RS11500	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JVX90_RS11505	COG5002	protein histidine kinase activity
JVX90_RS11510	COG0745	RESPONSE REGULATOR receiver
JVX90_RS11530	COG0477	Major facilitator Superfamily
JVX90_RS11545	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JVX90_RS11550	COG1461	Dihydroxyacetone kinase
JVX90_RS11555	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JVX90_RS11560	COG1024	Enoyl-CoA hydratase
JVX90_RS11570	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JVX90_RS11585	COG2304	oxidoreductase activity
JVX90_RS11590	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JVX90_RS11600	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JVX90_RS11605	COG0494	nUDIX hydrolase
JVX90_RS11605	COG0406	alpha-ribazole phosphatase activity
JVX90_RS11610	COG0776	regulation of translation
JVX90_RS11615	COG0066	3-isopropylmalate dehydratase activity
JVX90_RS11620	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JVX90_RS11630	COG3467	pyridoxamine 5'-phosphate
JVX90_RS11645	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JVX90_RS11655	COG0179	Fumarylacetoacetate (FAA) hydrolase
JVX90_RS11660	COG2271	Major facilitator Superfamily
JVX90_RS11695	COG0440	acetolactate synthase activity
JVX90_RS11710	COG2239	Acts as a magnesium transporter
JVX90_RS11715	COG0129	dihydroxy-acid dehydratase activity
JVX90_RS11730	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JVX90_RS11755	COG2197	response regulator
JVX90_RS11760	COG4585	Histidine kinase
JVX90_RS11775	COG0154	amidase activity
JVX90_RS11780	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JVX90_RS11795	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JVX90_RS11810	COG0482	sulfurtransferase activity
JVX90_RS11825	COG3629	intracellular signal transduction
JVX90_RS11825	COG3903	Transcriptional regulator
JVX90_RS11845	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
JVX90_RS11855	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JVX90_RS11895	COG0110	maltose O-acetyltransferase activity
JVX90_RS11910	COG2226	methyltransferase
JVX90_RS11980	COG1984	allophanate hydrolase subunit 2
JVX90_RS11985	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
JVX90_RS11990	COG0439	Biotin carboxylase
JVX90_RS12000	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
JVX90_RS12005	COG1942	4-Oxalocrotonate Tautomerase
JVX90_RS12015	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JVX90_RS12015	COG0543	2 iron, 2 sulfur cluster binding
JVX90_RS12045	COG1119	ATPase activity
JVX90_RS12050	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JVX90_RS12060	COG3830	Belongs to the UPF0237 family
JVX90_RS12060	COG0560	Phosphoserine phosphatase
JVX90_RS12075	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JVX90_RS12105	COG1063	alcohol dehydrogenase
JVX90_RS12155	COG1482	cell wall glycoprotein biosynthetic process
JVX90_RS12180	COG0391	Required for morphogenesis under gluconeogenic growth conditions
JVX90_RS12185	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
JVX90_RS12185	COG0778	Nitroreductase
JVX90_RS12220	COG0463	Glycosyl transferase, family 2
JVX90_RS12225	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JVX90_RS12230	COG0318	PFAM AMP-dependent synthetase and ligase
JVX90_RS12235	COG1611	Belongs to the LOG family
JVX90_RS12240	COG1611	Belongs to the LOG family
JVX90_RS12265	COG2171	N-acyltransferase activity
JVX90_RS12280	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
JVX90_RS12290	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JVX90_RS12295	COG4166	transmembrane transport
JVX90_RS12315	COG3842	ATPase activity
JVX90_RS12365	COG1012	belongs to the aldehyde dehydrogenase family
JVX90_RS12400	COG1960	acyl-CoA dehydrogenase activity
JVX90_RS12430	COG2197	response regulator
JVX90_RS12465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JVX90_RS12470	COG4172	Belongs to the ABC transporter superfamily
JVX90_RS12490	COG2197	response regulator
JVX90_RS12495	COG4585	Histidine kinase
JVX90_RS12500	COG1131	(ABC) transporter
JVX90_RS12520	COG1113	amino acid transport
JVX90_RS12550	COG2824	Alkylphosphonate utilization operon protein PhnA
JVX90_RS12615	COG0012	GTP binding
JVX90_RS12635	COG1322	Protein conserved in bacteria
JVX90_RS12645	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JVX90_RS12655	COG0860	N-Acetylmuramoyl-L-alanine amidase
JVX90_RS12670	COG1054	Belongs to the UPF0176 family
JVX90_RS12700	COG0765	amino acid transport
JVX90_RS12725	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
JVX90_RS12730	COG4139	cobalamin transport
JVX90_RS12755	COG2890	protein-(glutamine-N5) methyltransferase activity
JVX90_RS12765	COG0693	protein deglycase activity
JVX90_RS12780	COG3707	response regulator
JVX90_RS12820	COG2851	Citrate transporter
JVX90_RS12825	COG3290	protein histidine kinase activity
JVX90_RS12880	COG0488	(ABC) transporter
JVX90_RS12890	COG0477	Major facilitator Superfamily
JVX90_RS12900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JVX90_RS12935	COG2814	Major facilitator Superfamily
JVX90_RS12945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JVX90_RS12965	COG3706	GGDEF domain
JVX90_RS12980	COG2066	Belongs to the glutaminase family
JVX90_RS12995	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JVX90_RS13000	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JVX90_RS13005	COG1113	amino acid transport
JVX90_RS13030	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JVX90_RS13030	COG1796	DNA polymerase
JVX90_RS13055	COG0033	Phosphoglucomutase
JVX90_RS13065	COG1131	(ABC) transporter
JVX90_RS13085	COG0318	PFAM AMP-dependent synthetase and ligase
JVX90_RS13105	COG0582	viral genome integration into host DNA
JVX90_RS13120	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JVX90_RS13125	COG2177	Part of the ABC transporter FtsEX involved in
JVX90_RS13130	COG2884	Cell division ATP-binding protein ftsE
JVX90_RS13140	COG0668	transmembrane transport
JVX90_RS13145	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
JVX90_RS13155	COG0483	inositol monophosphate 1-phosphatase activity
JVX90_RS13165	COG1960	acyl-CoA dehydrogenase activity
JVX90_RS13170	COG1960	acyl-CoA dehydrogenase activity
JVX90_RS13175	COG1522	sequence-specific DNA binding
JVX90_RS13185	COG1687	branched-chain amino acid
JVX90_RS13215	COG3384	dioxygenase
JVX90_RS13220	COG1846	Transcriptional regulator
JVX90_RS13270	COG1615	UPF0182 protein
JVX90_RS13285	COG3480	Lon protease (S16) C-terminal proteolytic domain
JVX90_RS13300	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JVX90_RS13325	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JVX90_RS13340	COG0596	Alpha beta hydrolase
JVX90_RS13370	COG1309	transcriptional regulator
JVX90_RS13385	COG0513	Belongs to the DEAD box helicase family
JVX90_RS13395	COG1192	Involved in chromosome partitioning
JVX90_RS13405	COG1597	lipid kinase activity
JVX90_RS13420	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
JVX90_RS13430	COG1595	DNA-templated transcription, initiation
JVX90_RS13435	COG2135	peptidase activity
JVX90_RS13445	COG2072	flavoprotein involved in K transport
JVX90_RS13465	COG0656	L-ascorbic acid biosynthetic process
JVX90_RS13470	COG0436	Aminotransferase
JVX90_RS13495	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JVX90_RS13500	COG1162	GTPase activity
JVX90_RS13520	COG2318	DinB family
JVX90_RS13540	COG2354	Protein conserved in bacteria
JVX90_RS13545	COG0653	protein targeting
JVX90_RS13550	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JVX90_RS13565	COG5002	protein histidine kinase activity
JVX90_RS13570	COG0745	RESPONSE REGULATOR receiver
JVX90_RS13585	COG0531	amino acid
JVX90_RS13590	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JVX90_RS13860	COG1674	ftsk spoiiie
JVX90_RS13940	COG1252	NADH dehydrogenase
JVX90_RS13950	COG0318	PFAM AMP-dependent synthetase and ligase
JVX90_RS13975	COG0202	RNA polymerase activity
JVX90_RS13980	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JVX90_RS13985	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JVX90_RS13995	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JVX90_RS14000	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JVX90_RS14005	COG1950	PFAM Membrane protein of
JVX90_RS14015	COG1490	D-aminoacyl-tRNA deacylase activity
JVX90_RS14020	COG5650	phosphatidylinositol metabolic process
JVX90_RS14035	COG0563	adenylate kinase activity
JVX90_RS14060	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JVX90_RS14070	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JVX90_RS14085	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
JVX90_RS14090	COG0829	nickel cation binding
JVX90_RS14100	COG0804	urea catabolic process
JVX90_RS14105	COG0832	Belongs to the urease beta subunit family
JVX90_RS14110	COG0831	urea catabolic process
JVX90_RS14125	COG2860	membrane
JVX90_RS14140	COG0463	Glycosyl transferase, family 2
JVX90_RS14150	COG1216	Glycosyl transferase, family 2
JVX90_RS14150	COG1442	glycosyl transferase family 8
JVX90_RS14165	COG3706	GGDEF domain
JVX90_RS14175	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JVX90_RS14180	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JVX90_RS14190	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JVX90_RS14270	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JVX90_RS14290	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JVX90_RS14300	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JVX90_RS14305	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JVX90_RS14315	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JVX90_RS14320	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JVX90_RS14325	COG0089	rRNA binding
JVX90_RS14330	COG0088	Forms part of the polypeptide exit tunnel
JVX90_RS14335	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JVX90_RS14340	COG0051	transcription antitermination factor activity, RNA binding
JVX90_RS14390	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JVX90_RS14440	COG0535	radical SAM domain protein
JVX90_RS14510	COG4948	Mandelate Racemase Muconate Lactonizing
JVX90_RS14525	COG0346	lactoylglutathione lyase activity
JVX90_RS14550	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JVX90_RS14555	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JVX90_RS14560	COG0049	tRNA binding
JVX90_RS14565	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JVX90_RS14570	COG2186	Transcriptional regulator
JVX90_RS14575	COG2807	transmembrane transport
JVX90_RS14580	COG5343	regulation of RNA biosynthetic process
JVX90_RS14590	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JVX90_RS14625	COG3284	Transcriptional regulator
JVX90_RS14630	COG1012	belongs to the aldehyde dehydrogenase family
JVX90_RS14645	COG1309	transcriptional regulator
JVX90_RS14665	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JVX90_RS14690	COG4221	oxidoreductase activity
JVX90_RS14695	COG0183	Belongs to the thiolase family
JVX90_RS14700	COG1028	Short-chain dehydrogenase reductase Sdr
JVX90_RS14705	COG1169	isochorismate synthase
JVX90_RS14730	COG2124	cytochrome p450
JVX90_RS14735	COG4221	oxidoreductase activity
JVX90_RS14810	COG2755	lipolytic protein G-D-S-L family
JVX90_RS14815	COG1215	transferase activity, transferring glycosyl groups
JVX90_RS14840	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JVX90_RS14845	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
JVX90_RS14850	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JVX90_RS14900	COG2226	methyltransferase
JVX90_RS14905	COG0438	transferase activity, transferring glycosyl groups
JVX90_RS14945	COG0697	spore germination
JVX90_RS14995	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JVX90_RS15000	COG0085	RNA polymerase activity
JVX90_RS15045	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JVX90_RS15050	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JVX90_RS15060	COG0222	ribosome binding
JVX90_RS15110	COG0081	regulation of translation
JVX90_RS15115	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JVX90_RS15140	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JVX90_RS15160	COG1666	GTP binding
JVX90_RS15165	COG0501	Belongs to the peptidase M48B family
JVX90_RS15170	COG0142	geranyltranstransferase activity
JVX90_RS15180	COG2226	methyltransferase
JVX90_RS15190	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
JVX90_RS15200	COG3268	Saccharopine dehydrogenase
JVX90_RS15220	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JVX90_RS15230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JVX90_RS15275	COG0577	efflux transmembrane transporter activity
JVX90_RS15280	COG0577	efflux transmembrane transporter activity
JVX90_RS15280	COG1136	(ABC) transporter
JVX90_RS15300	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JVX90_RS15310	COG0785	Cytochrome C biogenesis protein
JVX90_RS15315	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JVX90_RS15320	COG0406	alpha-ribazole phosphatase activity
JVX90_RS15325	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JVX90_RS15330	COG2755	lipolytic protein G-D-S-L family
JVX90_RS15365	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JVX90_RS15440	COG5002	protein histidine kinase activity
JVX90_RS15450	COG0588	phosphoglycerate mutase activity
JVX90_RS15455	COG0318	PFAM AMP-dependent synthetase and ligase
JVX90_RS15465	COG0438	transferase activity, transferring glycosyl groups
JVX90_RS15475	COG1120	ATPase activity
JVX90_RS15480	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JVX90_RS15490	COG2272	Belongs to the type-B carboxylesterase lipase family
JVX90_RS15495	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
JVX90_RS15510	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JVX90_RS15515	COG0215	cysteine-tRNA ligase activity
JVX90_RS15525	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JVX90_RS15530	COG1329	Transcriptional regulator
JVX90_RS15540	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JVX90_RS15550	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
JVX90_RS15565	COG1194	a g-specific adenine glycosylase
JVX90_RS15570	COG0596	Alpha beta hydrolase
JVX90_RS15590	COG0745	RESPONSE REGULATOR receiver
JVX90_RS15595	COG3850	Histidine kinase
JVX90_RS15595	COG0642	Histidine kinase
JVX90_RS15645	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JVX90_RS15655	COG1028	Short-chain dehydrogenase reductase Sdr
JVX90_RS15665	COG1960	acyl-CoA dehydrogenase activity
JVX90_RS15670	COG1960	acyl-CoA dehydrogenase activity
JVX90_RS15675	COG0318	PFAM AMP-dependent synthetase and ligase
JVX90_RS15680	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JVX90_RS15685	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JVX90_RS15690	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JVX90_RS15695	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JVX90_RS15710	COG2070	2-Nitropropane dioxygenase
JVX90_RS15720	COG1024	Enoyl-CoA hydratase
JVX90_RS15730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JVX90_RS15765	COG2124	cytochrome p450
JVX90_RS15770	COG0183	Belongs to the thiolase family
JVX90_RS15775	COG0748	coenzyme F420 binding
JVX90_RS15790	COG0318	PFAM AMP-dependent synthetase and ligase
JVX90_RS15800	COG1028	Short-chain dehydrogenase reductase Sdr
JVX90_RS15805	COG1028	Short-chain dehydrogenase reductase Sdr
JVX90_RS15810	COG1024	Enoyl-CoA hydratase
JVX90_RS15840	COG2258	MOSC domain
JVX90_RS15845	COG1609	Transcriptional regulator
JVX90_RS15850	COG1960	acyl-CoA dehydrogenase activity
JVX90_RS15870	COG2813	Specifically methylates the guanine in position
JVX90_RS15895	COG1309	transcriptional regulator
JVX90_RS15910	COG1414	Transcriptional regulator
JVX90_RS15930	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
JVX90_RS15940	COG1012	belongs to the aldehyde dehydrogenase family
JVX90_RS15955	COG0183	Belongs to the thiolase family
JVX90_RS15960	COG1028	Short-chain dehydrogenase reductase Sdr
JVX90_RS15965	COG1960	acyl-CoA dehydrogenase activity
JVX90_RS15970	COG0318	PFAM AMP-dependent synthetase and ligase
JVX90_RS15975	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JVX90_RS15985	COG2318	DinB family
JVX90_RS15990	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JVX90_RS16005	COG1309	transcriptional regulator
JVX90_RS16035	COG2030	dehydratase
JVX90_RS16050	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
JVX90_RS16055	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JVX90_RS16080	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JVX90_RS16095	COG0302	gtp cyclohydrolase
JVX90_RS16100	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JVX90_RS16115	COG0037	tRNA processing
JVX90_RS16125	COG2027	D-alanyl-D-alanine carboxypeptidase
JVX90_RS16135	COG0477	Major facilitator Superfamily
JVX90_RS16145	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JVX90_RS16155	COG4260	virion core protein, lumpy skin disease virus
JVX90_RS16160	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JVX90_RS16200	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
JVX90_RS16220	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JVX90_RS16230	COG1994	Peptidase M50
JVX90_RS16235	COG0318	PFAM AMP-dependent synthetase and ligase
JVX90_RS16265	COG1960	acyl-CoA dehydrogenase activity
JVX90_RS16270	COG1028	Short-chain dehydrogenase reductase Sdr
JVX90_RS16275	COG2030	dehydratase
JVX90_RS16285	COG0183	Belongs to the thiolase family
JVX90_RS16300	COG4129	membrane
JVX90_RS16330	COG0748	coenzyme F420 binding
JVX90_RS16350	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JVX90_RS16370	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
JVX90_RS16375	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
JVX90_RS16400	COG1129	ABC transporter
JVX90_RS16400	COG0842	Transport permease protein
JVX90_RS16405	COG0542	response to heat
JVX90_RS16415	COG2197	response regulator
JVX90_RS16420	COG4585	Histidine kinase
JVX90_RS16425	COG2072	flavoprotein involved in K transport
JVX90_RS16440	COG1132	(ABC) transporter
JVX90_RS16445	COG1132	(ABC) transporter
JVX90_RS16455	COG4607	ABC-type enterochelin transport system periplasmic component
JVX90_RS16465	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JVX90_RS16470	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JVX90_RS16475	COG1120	ATPase activity
JVX90_RS16480	COG1073	alpha beta
JVX90_RS16560	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JVX90_RS16570	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JVX90_RS16580	COG2233	PERMEase
JVX90_RS16610	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JVX90_RS16610	COG1017	nitric oxide dioxygenase activity
JVX90_RS16615	COG0789	Transcriptional regulator
JVX90_RS16620	COG0783	Belongs to the Dps family
JVX90_RS16625	COG3237	CsbD-like
JVX90_RS16635	COG0702	epimerase
JVX90_RS16670	COG0789	Transcriptional regulator
JVX90_RS16675	COG0484	heat shock protein binding
JVX90_RS16680	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JVX90_RS16685	COG0443	Heat shock 70 kDa protein
JVX90_RS16705	COG0681	Belongs to the peptidase S26 family
JVX90_RS16730	COG3599	regulation of cell shape
JVX90_RS16740	COG4585	Histidine kinase
JVX90_RS16745	COG2197	response regulator
JVX90_RS16790	COG2181	nitrate reductase activity
JVX90_RS16790	COG0247	lactate metabolic process
JVX90_RS16875	COG0477	Major facilitator Superfamily
JVX90_RS16930	COG0183	Belongs to the thiolase family
JVX90_RS16975	COG2022	thiamine diphosphate biosynthetic process
JVX90_RS16985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JVX90_RS16985	COG2022	thiamine diphosphate biosynthetic process
JVX90_RS16990	COG0352	thiamine-phosphate diphosphorylase activity
JVX90_RS17010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JVX90_RS17040	COG1793	dna ligase
JVX90_RS17040	COG3285	dna ligase
JVX90_RS17045	COG1793	dna ligase
JVX90_RS17050	COG1522	sequence-specific DNA binding
JVX90_RS17075	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JVX90_RS17105	COG0343	queuine tRNA-ribosyltransferase activity
JVX90_RS17115	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JVX90_RS17120	COG1181	Belongs to the D-alanine--D-alanine ligase family
JVX90_RS17155	COG0287	Prephenate dehydrogenase
JVX90_RS17190	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JVX90_RS17210	COG2197	response regulator
JVX90_RS17215	COG4585	Histidine kinase
JVX90_RS17225	COG1131	(ABC) transporter
JVX90_RS17255	COG4221	oxidoreductase activity
JVX90_RS17265	COG2855	membrane
JVX90_RS17300	COG4977	sequence-specific DNA binding
JVX90_RS17305	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JVX90_RS17335	COG0477	Major facilitator Superfamily
JVX90_RS17375	COG1115	amino acid carrier protein
JVX90_RS17390	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JVX90_RS17400	COG1012	belongs to the aldehyde dehydrogenase family
JVX90_RS17420	COG0318	PFAM AMP-dependent synthetase and ligase
JVX90_RS17435	COG2072	flavoprotein involved in K transport
JVX90_RS17465	COG1028	Short-chain dehydrogenase reductase Sdr
JVX90_RS17465	COG3321	synthase
JVX90_RS17465	COG0604	alcohol dehydrogenase
JVX90_RS17495	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
JVX90_RS17505	COG0577	efflux transmembrane transporter activity
JVX90_RS17505	COG1136	(ABC) transporter
JVX90_RS17515	COG2197	response regulator
JVX90_RS17525	COG0326	Molecular chaperone. Has ATPase activity
JVX90_RS17530	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
JVX90_RS17535	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
JVX90_RS17540	COG0431	NADPH-dependent FMN reductase
JVX90_RS17540	COG1053	succinate dehydrogenase
JVX90_RS17540	COG3976	FMN-binding domain protein
JVX90_RS17545	COG2267	carboxylic ester hydrolase activity
JVX90_RS17555	COG1937	Protein conserved in bacteria
JVX90_RS17610	COG0583	DNA-binding transcription factor activity
JVX90_RS17625	COG0328	RNA-DNA hybrid ribonuclease activity
JVX90_RS17640	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
JVX90_RS17645	COG1960	acyl-CoA dehydrogenase activity
JVX90_RS17650	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JVX90_RS17655	COG1960	acyl-CoA dehydrogenase activity
JVX90_RS17670	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
JVX90_RS17680	COG1846	Transcriptional regulator
JVX90_RS17685	COG2755	lipolytic protein G-D-S-L family
JVX90_RS17695	COG1846	Transcriptional regulator
JVX90_RS17725	COG1028	Short-chain dehydrogenase reductase Sdr
JVX90_RS17735	COG0596	Alpha beta hydrolase
JVX90_RS17750	COG0477	Major facilitator Superfamily
JVX90_RS17760	COG1028	Short-chain dehydrogenase reductase Sdr
JVX90_RS17795	COG2814	Major facilitator Superfamily
JVX90_RS17800	COG2072	flavoprotein involved in K transport
JVX90_RS17805	COG1028	Short-chain dehydrogenase reductase Sdr
JVX90_RS17810	COG0657	acetylesterase activity
JVX90_RS17825	COG2409	Drug exporters of the RND superfamily
JVX90_RS17835	COG2072	flavoprotein involved in K transport
JVX90_RS17840	COG4221	oxidoreductase activity
JVX90_RS17845	COG4689	acetoacetate decarboxylase
JVX90_RS17850	COG0446	pyridine nucleotide-disulphide oxidoreductase
JVX90_RS17850	COG1902	pentaerythritol trinitrate reductase activity
JVX90_RS17855	COG1403	HNH endonuclease
JVX90_RS17865	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JVX90_RS17890	COG0305	Participates in initiation and elongation during chromosome replication
JVX90_RS17915	COG1309	transcriptional regulator
JVX90_RS17935	COG0183	Belongs to the thiolase family
JVX90_RS17940	COG0359	binds to the 23S rRNA
JVX90_RS17945	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JVX90_RS17970	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JVX90_RS17980	COG1695	Transcriptional regulator
JVX90_RS17985	COG1260	myo-inositol-1-phosphate synthase
JVX90_RS18015	COG1358	cellular component organization or biogenesis
JVX90_RS18045	COG0137	argininosuccinate synthase activity
JVX90_RS18055	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
JVX90_RS18070	COG0277	FAD linked oxidase domain protein
JVX90_RS18085	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JVX90_RS18110	COG2197	response regulator
JVX90_RS18120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JVX90_RS18130	COG1595	DNA-templated transcription, initiation
JVX90_RS18175	COG4221	oxidoreductase activity
JVX90_RS18180	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JVX90_RS18215	COG3631	Ketosteroid isomerase-related protein
JVX90_RS18220	COG1742	UPF0060 membrane protein
JVX90_RS18225	COG1960	acyl-CoA dehydrogenase activity
JVX90_RS18250	COG1690	Belongs to the RtcB family
JVX90_RS18255	COG0495	leucyl-tRNA aminoacylation
JVX90_RS18275	COG1678	Uncharacterized ACR, COG1678
JVX90_RS18290	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JVX90_RS18295	COG0617	tRNA 3'-terminal CCA addition
JVX90_RS18315	COG0519	Catalyzes the synthesis of GMP from XMP
JVX90_RS18395	COG1595	DNA-templated transcription, initiation
JVX90_RS18415	COG0860	N-Acetylmuramoyl-L-alanine amidase
JVX90_RS18415	COG3409	Peptidoglycan-binding domain 1 protein
JVX90_RS18430	COG1192	Involved in chromosome partitioning
JVX90_RS18435	COG0357	Ribosomal RNA small subunit methyltransferase G
JVX90_RS18445	COG0706	membrane insertase activity
JVX90_RS18455	COG0594	ribonuclease P activity
JVX90_RS18470	COG0592	DNA-directed DNA polymerase activity
JVX90_RS18475	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
JVX90_RS18480	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JVX90_RS18485	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
JVX90_RS18490	COG0187	DNA topoisomerase II activity
JVX90_RS18540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JVX90_RS18555	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JVX90_RS18580	COG0515	serine threonine protein kinase
JVX90_RS18580	COG2815	serine threonine protein kinase
JVX90_RS18585	COG0515	serine threonine protein kinase
JVX90_RS18590	COG0768	penicillin binding
JVX90_RS18605	COG1716	ATPase activity
JVX90_RS18610	COG1716	ATPase activity
JVX90_RS18665	COG0667	Aldo Keto reductase
JVX90_RS18695	COG1028	Short-chain dehydrogenase reductase Sdr
JVX90_RS18710	COG1028	Short-chain dehydrogenase reductase Sdr
JVX90_RS18720	COG1028	Short-chain dehydrogenase reductase Sdr
JVX90_RS18725	COG0656	L-ascorbic acid biosynthetic process
JVX90_RS18730	COG0477	Major facilitator Superfamily
JVX90_RS18750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JVX90_RS18755	COG1309	transcriptional regulator
JVX90_RS18805	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JVX90_RS18820	COG0300	oxidoreductase activity
JVX90_RS18835	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JVX90_RS18850	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JVX90_RS18860	COG0531	amino acid
JVX90_RS18870	COG0443	Heat shock 70 kDa protein
JVX90_RS18885	COG3304	Inner membrane component domain
JVX90_RS18915	COG0318	PFAM AMP-dependent synthetase and ligase
JVX90_RS18920	COG0657	acetylesterase activity
JVX90_RS18925	COG0067	glutamate synthase
JVX90_RS18925	COG0070	glutamate synthase
JVX90_RS18925	COG0069	glutamate synthase activity
JVX90_RS18950	COG4152	abc transporter atp-binding protein
JVX90_RS18960	COG1476	TRANSCRIPTIONal
JVX90_RS19025	COG2501	S4 domain
JVX90_RS19030	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JVX90_RS19030	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JVX90_RS19035	COG4335	DNA alkylation repair
JVX90_RS19045	COG1012	belongs to the aldehyde dehydrogenase family
JVX90_RS19070	COG2119	membrane
JVX90_RS19100	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JVX90_RS19110	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JVX90_RS19125	COG0425	Belongs to the sulfur carrier protein TusA family
JVX90_RS19125	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JVX90_RS19150	COG1528	Iron-storage protein
JVX90_RS19155	COG1316	TRANSCRIPTIONal
JVX90_RS19165	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JVX90_RS19185	COG0077	Prephenate dehydratase
JVX90_RS19215	COG1960	acyl-CoA dehydrogenase activity
JVX90_RS19230	COG0561	phosphatase activity
JVX90_RS19235	COG2385	sporulation resulting in formation of a cellular spore
JVX90_RS19245	COG1216	Glycosyl transferase, family 2
JVX90_RS19250	COG0671	phosphoesterase, PA-phosphatase related
JVX90_RS19255	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
JVX90_RS19260	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JVX90_RS19285	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
JVX90_RS19290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JVX90_RS19295	COG0318	PFAM AMP-dependent synthetase and ligase
JVX90_RS19300	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
JVX90_RS19300	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JVX90_RS19300	COG3321	synthase
JVX90_RS19305	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JVX90_RS19350	COG0346	lactoylglutathione lyase activity
JVX90_RS19360	COG5285	phytanoyl-CoA dioxygenase
JVX90_RS19375	COG0513	Belongs to the DEAD box helicase family
JVX90_RS19390	COG1028	Short-chain dehydrogenase reductase Sdr
JVX90_RS19395	COG0277	FAD linked oxidase domain protein
JVX90_RS19430	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
JVX90_RS19435	COG2030	dehydratase
JVX90_RS19445	COG1216	Glycosyl transferase, family 2
JVX90_RS19490	COG1960	acyl-CoA dehydrogenase activity
JVX90_RS19505	COG1304	FMN binding
JVX90_RS19555	COG1028	Short-chain dehydrogenase reductase Sdr
JVX90_RS19590	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
JVX90_RS19595	COG1309	transcriptional regulator
JVX90_RS19600	COG0183	Belongs to the thiolase family
JVX90_RS19605	COG1024	Enoyl-CoA hydratase
JVX90_RS19605	COG1250	3-hydroxyacyl-CoA dehydrogenase
JVX90_RS19615	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
JVX90_RS19630	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JVX90_RS19640	COG0446	pyridine nucleotide-disulphide oxidoreductase
JVX90_RS19660	COG1376	ErfK ybiS ycfS ynhG family protein
JVX90_RS19665	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JVX90_RS19670	COG1760	l-serine dehydratase
JVX90_RS19675	COG0583	DNA-binding transcription factor activity
JVX90_RS19680	COG0697	spore germination
JVX90_RS19685	COG3590	peptidase
JVX90_RS19720	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JVX90_RS19740	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
JVX90_RS19745	COG0577	efflux transmembrane transporter activity
JVX90_RS19745	COG1136	(ABC) transporter
JVX90_RS19760	COG0500	methyltransferase
JVX90_RS19765	COG0438	transferase activity, transferring glycosyl groups
JVX90_RS19775	COG2301	Belongs to the HpcH HpaI aldolase family
JVX90_RS19805	COG4981	capsule polysaccharide biosynthetic process
JVX90_RS19815	COG1472	Belongs to the glycosyl hydrolase 3 family
JVX90_RS19820	COG1309	transcriptional regulator
JVX90_RS19830	COG2030	dehydratase
JVX90_RS19835	COG1028	Short-chain dehydrogenase reductase Sdr
JVX90_RS19840	COG0183	Belongs to the thiolase family
JVX90_RS19870	COG2814	Major facilitator Superfamily
JVX90_RS19905	COG0477	Major facilitator Superfamily
JVX90_RS19910	COG0747	negative chemotaxis
JVX90_RS19920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JVX90_RS19925	COG4172	Belongs to the ABC transporter superfamily
JVX90_RS19930	COG1960	acyl-CoA dehydrogenase activity
JVX90_RS19960	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JVX90_RS19980	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JVX90_RS20005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JVX90_RS20015	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JVX90_RS20030	COG0564	pseudouridine synthase activity
JVX90_RS20040	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JVX90_RS20045	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JVX90_RS20055	COG1609	Transcriptional regulator
JVX90_RS20065	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JVX90_RS20070	COG1116	anion transmembrane transporter activity
JVX90_RS20080	COG3442	glutamine amidotransferase
JVX90_RS20085	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JVX90_RS20095	COG0477	Major facilitator Superfamily
JVX90_RS20100	COG0657	acetylesterase activity
JVX90_RS20105	COG0477	Major facilitator Superfamily
JVX90_RS20125	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JVX90_RS20130	COG0477	Major facilitator Superfamily
JVX90_RS20135	COG3842	ATPase activity
JVX90_RS20140	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
JVX90_RS20145	COG1176	ABC-type spermidine putrescine transport system, permease component I
JVX90_RS20150	COG1177	transmembrane transport
JVX90_RS20195	COG1764	response to oxidative stress
JVX90_RS20215	COG3655	Transcriptional regulator
JVX90_RS20245	COG1408	metallophosphoesterase
JVX90_RS20250	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
JVX90_RS20260	COG4399	Belongs to the UPF0754 family
JVX90_RS20285	COG0251	oxidation-reduction process
JVX90_RS20310	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JVX90_RS20325	COG0596	Alpha beta hydrolase
JVX90_RS20345	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JVX90_RS20365	COG0318	PFAM AMP-dependent synthetase and ligase
JVX90_RS20410	COG1205	dead DEAH box helicase
JVX90_RS20410	COG1111	helicase
JVX90_RS20415	COG1278	Cold shock
JVX90_RS20425	COG1754	DNA topoisomerase type I activity
JVX90_RS20425	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JVX90_RS20445	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JVX90_RS20450	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity