locus-tag	class	description
HUN08_RS00010	COG0592	DNA-directed DNA polymerase activity
HUN08_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HUN08_RS00020	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
HUN08_RS00025	COG0187	DNA topoisomerase II activity
HUN08_RS00050	COG2936	dipeptidyl-peptidase activity
HUN08_RS00065	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HUN08_RS00070	COG0705	Rhomboid family
HUN08_RS00070	COG0457	Tetratricopeptide repeat
HUN08_RS00100	COG0515	serine threonine protein kinase
HUN08_RS00105	COG0768	penicillin binding
HUN08_RS00120	COG1716	ATPase activity
HUN08_RS00125	COG1716	ATPase activity
HUN08_RS00135	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HUN08_RS00145	COG4399	Belongs to the UPF0754 family
HUN08_RS00160	COG3243	poly(R)-hydroxyalkanoic acid synthase
HUN08_RS00180	COG4221	oxidoreductase activity
HUN08_RS00205	COG2814	Major facilitator Superfamily
HUN08_RS00215	COG0477	Major facilitator Superfamily
HUN08_RS00225	COG1793	dna ligase
HUN08_RS00245	COG1704	LemA family
HUN08_RS00260	COG0657	acetylesterase activity
HUN08_RS00265	COG0069	glutamate synthase activity
HUN08_RS00265	COG0070	glutamate synthase
HUN08_RS00265	COG0067	glutamate synthase
HUN08_RS00275	COG3781	membrane
HUN08_RS00295	COG2501	S4 domain
HUN08_RS00300	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HUN08_RS00300	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HUN08_RS00310	COG1012	belongs to the aldehyde dehydrogenase family
HUN08_RS00330	COG1595	DNA-templated transcription, initiation
HUN08_RS00345	COG4762	Protein conserved in bacteria
HUN08_RS00385	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HUN08_RS00415	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HUN08_RS00440	COG1316	TRANSCRIPTIONal
HUN08_RS00470	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HUN08_RS00475	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HUN08_RS00480	COG0077	Prephenate dehydratase
HUN08_RS00500	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HUN08_RS00555	COG0204	Acyl-transferase
HUN08_RS00565	COG0204	Acyl-transferase
HUN08_RS00570	COG0561	phosphatase activity
HUN08_RS00575	COG2385	sporulation resulting in formation of a cellular spore
HUN08_RS00595	COG1216	Glycosyl transferase, family 2
HUN08_RS00600	COG0671	phosphoesterase, PA-phosphatase related
HUN08_RS00605	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HUN08_RS00610	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HUN08_RS00615	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
HUN08_RS00640	COG0318	PFAM AMP-dependent synthetase and ligase
HUN08_RS00645	COG3321	synthase
HUN08_RS00645	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUN08_RS00650	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUN08_RS00680	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
HUN08_RS00690	COG1028	Short-chain dehydrogenase reductase Sdr
HUN08_RS00695	COG0277	FAD linked oxidase domain protein
HUN08_RS00735	COG1216	Glycosyl transferase, family 2
HUN08_RS00775	COG3321	synthase
HUN08_RS00775	COG0604	alcohol dehydrogenase
HUN08_RS00785	COG2076	Multidrug Resistance protein
HUN08_RS00810	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
HUN08_RS00825	COG0318	PFAM AMP-dependent synthetase and ligase
HUN08_RS00830	COG1021	2,3-dihydroxybenzoate-AMP ligase
HUN08_RS00860	COG3486	L-lysine 6-monooxygenase (NADPH) activity
HUN08_RS00875	COG0183	Belongs to the thiolase family
HUN08_RS00885	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HUN08_RS00890	COG3012	SEC-C Motif Domain Protein
HUN08_RS00925	COG0270	DNA (cytosine-5-)-methyltransferase activity
HUN08_RS01005	COG2409	Drug exporters of the RND superfamily
HUN08_RS01020	COG0254	rRNA binding
HUN08_RS01030	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HUN08_RS01040	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HUN08_RS01045	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HUN08_RS01090	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HUN08_RS01120	COG1063	alcohol dehydrogenase
HUN08_RS01135	COG0183	Belongs to the thiolase family
HUN08_RS01145	COG0287	Prephenate dehydrogenase
HUN08_RS01155	COG0590	tRNA wobble adenosine to inosine editing
HUN08_RS01200	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUN08_RS01205	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HUN08_RS01210	COG1034	ATP synthesis coupled electron transport
HUN08_RS01215	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HUN08_RS01225	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUN08_RS01230	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUN08_RS01250	COG1181	Belongs to the D-alanine--D-alanine ligase family
HUN08_RS01255	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HUN08_RS01270	COG0789	Transcriptional regulator
HUN08_RS01280	COG0343	queuine tRNA-ribosyltransferase activity
HUN08_RS01285	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HUN08_RS01295	COG1793	dna ligase
HUN08_RS01320	COG3158	transport of potassium into the cell
HUN08_RS01350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUN08_RS01355	COG5650	phosphatidylinositol metabolic process
HUN08_RS01370	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HUN08_RS01385	COG0564	pseudouridine synthase activity
HUN08_RS01405	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HUN08_RS01420	COG3442	glutamine amidotransferase
HUN08_RS01425	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HUN08_RS01435	COG0477	Major facilitator Superfamily
HUN08_RS01440	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HUN08_RS01445	COG0477	Major facilitator Superfamily
HUN08_RS01460	COG2264	protein methyltransferase activity
HUN08_RS01510	COG0477	Major facilitator Superfamily
HUN08_RS01545	COG1073	alpha beta
HUN08_RS01565	COG1764	response to oxidative stress
HUN08_RS01585	COG1408	metallophosphoesterase
HUN08_RS01590	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HUN08_RS01600	COG0003	Pfam Anion-transporting ATPase
HUN08_RS01645	COG0494	nUDIX hydrolase
HUN08_RS01655	COG0596	Alpha beta hydrolase
HUN08_RS01665	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUN08_RS01690	COG2197	response regulator
HUN08_RS01740	COG1741	Belongs to the pirin family
HUN08_RS01745	COG1111	helicase
HUN08_RS01745	COG1205	dead DEAH box helicase
HUN08_RS01750	COG1278	Cold shock
HUN08_RS01760	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HUN08_RS01785	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HUN08_RS01785	COG1754	DNA topoisomerase type I activity
HUN08_RS01795	COG0470	DNA polymerase III
HUN08_RS01800	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUN08_RS01895	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HUN08_RS01900	COG1088	dTDP-glucose 4,6-dehydratase activity
HUN08_RS01905	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HUN08_RS01910	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
HUN08_RS01920	COG2259	Doxx family
HUN08_RS01945	COG0657	acetylesterase activity
HUN08_RS01950	COG1960	acyl-CoA dehydrogenase activity
HUN08_RS01955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUN08_RS01960	COG1309	transcriptional regulator
HUN08_RS01970	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HUN08_RS01975	COG3795	YCII-related domain
HUN08_RS01980	COG4941	Belongs to the sigma-70 factor family
HUN08_RS01990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUN08_RS02020	COG1403	HNH endonuclease
HUN08_RS02025	COG0352	thiamine-phosphate diphosphorylase activity
HUN08_RS02040	COG2022	thiamine diphosphate biosynthetic process
HUN08_RS02045	COG0477	Major facilitator Superfamily
HUN08_RS02050	COG0351	phosphomethylpyrimidine kinase
HUN08_RS02055	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HUN08_RS02075	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HUN08_RS02080	COG0657	acetylesterase activity
HUN08_RS02085	COG2072	flavoprotein involved in K transport
HUN08_RS02110	COG0756	dUTP diphosphatase activity
HUN08_RS02115	COG0756	dUTP diphosphatase activity
HUN08_RS02150	COG4221	oxidoreductase activity
HUN08_RS02190	COG2032	superoxide dismutase activity
HUN08_RS02205	COG2212	antiporter activity
HUN08_RS02225	COG2111	Na H antiporter
HUN08_RS02225	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HUN08_RS02235	COG1937	Protein conserved in bacteria
HUN08_RS02250	COG0688	phosphatidylethanolamine metabolic process
HUN08_RS02260	COG3766	membrane
HUN08_RS02265	COG1960	acyl-CoA dehydrogenase activity
HUN08_RS02270	COG1960	acyl-CoA dehydrogenase activity
HUN08_RS02290	COG2723	6-phospho-beta-galactosidase activity
HUN08_RS02375	COG1505	serine-type exopeptidase activity
HUN08_RS02400	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HUN08_RS02415	COG1131	(ABC) transporter
HUN08_RS02435	COG2226	methyltransferase
HUN08_RS02480	COG2224	Isocitrate lyase
HUN08_RS02490	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HUN08_RS02495	COG2326	polyphosphate kinase activity
HUN08_RS02505	COG2733	membrane
HUN08_RS02535	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HUN08_RS02560	COG0788	formyltetrahydrofolate deformylase activity
HUN08_RS02565	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HUN08_RS02610	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HUN08_RS02620	COG2909	trisaccharide binding
HUN08_RS02620	COG2909	trisaccharide binding
HUN08_RS02655	COG0745	RESPONSE REGULATOR receiver
HUN08_RS02660	COG2205	protein histidine kinase activity
HUN08_RS02675	COG0514	ATP-dependent DNA helicase (RecQ)
HUN08_RS02710	COG1960	acyl-CoA dehydrogenase activity
HUN08_RS02725	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HUN08_RS02735	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
HUN08_RS02760	COG2030	dehydratase
HUN08_RS02765	COG0477	Major facilitator Superfamily
HUN08_RS02775	COG0386	Belongs to the glutathione peroxidase family
HUN08_RS02780	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HUN08_RS02785	COG0047	phosphoribosylformylglycinamidine synthase activity
HUN08_RS02790	COG1362	aminopeptidase activity
HUN08_RS02830	COG1309	transcriptional regulator
HUN08_RS02835	COG1960	acyl-CoA dehydrogenase activity
HUN08_RS02845	COG1960	acyl-CoA dehydrogenase activity
HUN08_RS02850	COG2030	dehydratase
HUN08_RS02855	COG0183	Belongs to the thiolase family
HUN08_RS02875	COG0477	Major facilitator Superfamily
HUN08_RS02890	COG2030	dehydratase
HUN08_RS02895	COG1053	succinate dehydrogenase
HUN08_RS02900	COG3971	2-oxopent-4-enoate hydratase activity
HUN08_RS02905	COG4569	acetaldehyde dehydrogenase (acetylating) activity
HUN08_RS02910	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HUN08_RS02995	COG1960	acyl-CoA dehydrogenase activity
HUN08_RS03000	COG0346	lactoylglutathione lyase activity
HUN08_RS03005	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HUN08_RS03015	COG1028	Short-chain dehydrogenase reductase Sdr
HUN08_RS03025	COG1960	acyl-CoA dehydrogenase activity
HUN08_RS03030	COG1960	acyl-CoA dehydrogenase activity
HUN08_RS03035	COG1960	acyl-CoA dehydrogenase activity
HUN08_RS03040	COG1024	Enoyl-CoA hydratase
HUN08_RS03070	COG0175	sulfate reduction
HUN08_RS03080	COG1218	3'(2'),5'-bisphosphate nucleotidase
HUN08_RS03130	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUN08_RS03195	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
HUN08_RS03205	COG0354	folic acid binding
HUN08_RS03220	COG1271	oxidase subunit
HUN08_RS03225	COG1294	oxidase, subunit
HUN08_RS03230	COG4988	ABC transporter
HUN08_RS03235	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HUN08_RS03245	COG4044	May play a role in the intracellular transport of hydrophobic ligands
HUN08_RS03265	COG1024	Enoyl-CoA hydratase
HUN08_RS03275	COG2897	thiosulfate sulfurtransferase activity
HUN08_RS03285	COG0745	RESPONSE REGULATOR receiver
HUN08_RS03290	COG0456	acetyltransferase
HUN08_RS03290	COG0454	-acetyltransferase
HUN08_RS03415	COG2855	membrane
HUN08_RS03445	COG2353	YceI-like domain
HUN08_RS03525	COG1278	Cold shock
HUN08_RS03535	COG2814	Major facilitator Superfamily
HUN08_RS03550	COG0671	phosphoesterase, PA-phosphatase related
HUN08_RS03565	COG2252	PERMEase
HUN08_RS03575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUN08_RS03595	COG2197	response regulator
HUN08_RS03620	COG1309	transcriptional regulator
HUN08_RS03625	COG1131	(ABC) transporter
HUN08_RS03635	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HUN08_RS03655	COG2814	Major facilitator Superfamily
HUN08_RS03675	COG1984	allophanate hydrolase subunit 2
HUN08_RS03680	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HUN08_RS03690	COG0545	Peptidyl-prolyl cis-trans isomerase
HUN08_RS03720	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HUN08_RS03725	COG2094	Belongs to the DNA glycosylase MPG family
HUN08_RS03750	COG1218	3'(2'),5'-bisphosphate nucleotidase
HUN08_RS03755	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HUN08_RS03790	COG0667	Aldo Keto reductase
HUN08_RS03795	COG0259	pyridoxamine-phosphate oxidase activity
HUN08_RS03810	COG4942	peptidase
HUN08_RS03815	COG0045	succinate-CoA ligase (ADP-forming) activity
HUN08_RS03845	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUN08_RS03855	COG1960	acyl-CoA dehydrogenase activity
HUN08_RS03880	COG0318	PFAM AMP-dependent synthetase and ligase
HUN08_RS03895	COG1984	allophanate hydrolase subunit 2
HUN08_RS03945	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
HUN08_RS03975	COG5473	translation initiation factor activity
HUN08_RS03990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUN08_RS04015	COG1132	(ABC) transporter
HUN08_RS04020	COG1970	mechanosensitive ion channel activity
HUN08_RS04035	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HUN08_RS04040	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HUN08_RS04050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUN08_RS04060	COG0842	Transport permease protein
HUN08_RS04065	COG0842	Transport permease protein
HUN08_RS04065	COG1129	ABC transporter
HUN08_RS04115	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HUN08_RS04135	COG2205	protein histidine kinase activity
HUN08_RS04140	COG0745	RESPONSE REGULATOR receiver
HUN08_RS04145	COG0513	Belongs to the DEAD box helicase family
HUN08_RS04150	COG2272	Belongs to the type-B carboxylesterase lipase family
HUN08_RS04170	COG0589	response to stress
HUN08_RS04175	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HUN08_RS04230	COG0384	phenazine biosynthesis protein PhzF
HUN08_RS04235	COG0084	hydrolase, TatD family'
HUN08_RS04240	COG3583	domain protein
HUN08_RS04245	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HUN08_RS04250	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HUN08_RS04260	COG0488	(ABC) transporter
HUN08_RS04280	COG0488	(ABC) transporter
HUN08_RS04315	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HUN08_RS04350	COG2072	flavoprotein involved in K transport
HUN08_RS04355	COG0318	PFAM AMP-dependent synthetase and ligase
HUN08_RS04370	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
HUN08_RS04380	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUN08_RS04385	COG0193	aminoacyl-tRNA hydrolase activity
HUN08_RS04420	COG1131	(ABC) transporter
HUN08_RS04430	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
HUN08_RS04510	COG1247	-acetyltransferase
HUN08_RS04530	COG2837	iron assimilation
HUN08_RS04550	COG0148	phosphopyruvate hydratase activity
HUN08_RS04640	COG2267	carboxylic ester hydrolase activity
HUN08_RS04650	COG0745	RESPONSE REGULATOR receiver
HUN08_RS04655	COG3850	Histidine kinase
HUN08_RS04655	COG5002	protein histidine kinase activity
HUN08_RS04665	COG0671	phosphoesterase, PA-phosphatase related
HUN08_RS04675	COG0604	alcohol dehydrogenase
HUN08_RS04690	COG1028	Short-chain dehydrogenase reductase Sdr
HUN08_RS04695	COG1960	acyl-CoA dehydrogenase activity
HUN08_RS04700	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
HUN08_RS04710	COG0135	phosphoribosylanthranilate isomerase activity
HUN08_RS04755	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HUN08_RS04780	COG2197	response regulator
HUN08_RS04800	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HUN08_RS04845	COG1024	Enoyl-CoA hydratase
HUN08_RS04860	COG1741	Belongs to the pirin family
HUN08_RS04885	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HUN08_RS04905	COG2409	Drug exporters of the RND superfamily
HUN08_RS04920	COG0183	Belongs to the thiolase family
HUN08_RS04925	COG2755	lipolytic protein G-D-S-L family
HUN08_RS04950	COG1228	amidohydrolase
HUN08_RS04955	COG1309	transcriptional regulator
HUN08_RS04960	COG2409	Drug exporters of the RND superfamily
HUN08_RS04975	COG3177	Filamentation induced by cAMP protein fic
HUN08_RS04985	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HUN08_RS05010	COG1331	Highly conserved protein containing a thioredoxin domain
HUN08_RS05025	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HUN08_RS05045	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HUN08_RS05060	COG1072	(Pantothenic acid kinase))
HUN08_RS05070	COG0477	Major facilitator Superfamily
HUN08_RS05080	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HUN08_RS05090	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
HUN08_RS05125	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HUN08_RS05125	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HUN08_RS05130	COG2197	response regulator
HUN08_RS05150	COG1494	fructose-1,6-bisphosphatase
HUN08_RS05160	COG1722	exodeoxyribonuclease VII activity
HUN08_RS05165	COG1570	exodeoxyribonuclease VII activity
HUN08_RS05175	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HUN08_RS05190	COG1404	Belongs to the peptidase S8 family
HUN08_RS05200	COG1674	ftsk spoiiie
HUN08_RS05210	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HUN08_RS05225	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HUN08_RS05230	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HUN08_RS05265	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HUN08_RS05280	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HUN08_RS05305	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HUN08_RS05310	COG1028	Short-chain dehydrogenase reductase Sdr
HUN08_RS05315	COG3433	isochorismatase activity
HUN08_RS05315	COG1535	isochorismatase
HUN08_RS05325	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HUN08_RS05325	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUN08_RS05330	COG1021	2,3-dihydroxybenzoate-AMP ligase
HUN08_RS05335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUN08_RS05340	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUN08_RS05345	COG1120	ATPase activity
HUN08_RS05350	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
HUN08_RS05350	COG1473	amidohydrolase
HUN08_RS05395	COG0516	GMP reductase activity
HUN08_RS05415	COG1487	ribonuclease activity
HUN08_RS05425	COG3708	Transcriptional regulator
HUN08_RS05425	COG2207	Transcriptional regulator
HUN08_RS05445	COG2815	serine threonine protein kinase
HUN08_RS05445	COG0515	serine threonine protein kinase
HUN08_RS05490	COG0587	DNA-directed DNA polymerase activity
HUN08_RS05505	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HUN08_RS05510	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HUN08_RS05525	COG2873	o-acetylhomoserine
HUN08_RS05555	COG0180	Tryptophanyl-tRNA synthetase
HUN08_RS05560	COG1295	ribonuclease BN
HUN08_RS05585	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HUN08_RS05600	COG2009	succinate dehydrogenase
HUN08_RS05625	COG0791	NLP P60 protein
HUN08_RS05625	COG0741	lytic transglycosylase activity
HUN08_RS05640	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HUN08_RS05700	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HUN08_RS05705	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HUN08_RS05715	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HUN08_RS05730	COG1201	RNA secondary structure unwinding
HUN08_RS05775	COG1960	acyl-CoA dehydrogenase activity
HUN08_RS05780	COG2072	flavoprotein involved in K transport
HUN08_RS05785	COG2508	Transcriptional regulator
HUN08_RS05800	COG1396	sequence-specific DNA binding
HUN08_RS05800	COG3800	Transcriptional regulator
HUN08_RS05810	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HUN08_RS05830	COG2814	Major facilitator Superfamily
HUN08_RS05900	COG4770	biotin carboxylase activity
HUN08_RS05920	COG0424	maF-like protein
HUN08_RS05930	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUN08_RS05935	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
HUN08_RS05935	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
HUN08_RS05950	COG0745	RESPONSE REGULATOR receiver
HUN08_RS06030	COG1316	TRANSCRIPTIONal
HUN08_RS06050	COG4122	O-methyltransferase activity
HUN08_RS06055	COG1595	DNA-templated transcription, initiation
HUN08_RS06060	COG5662	AntiSigma factor
HUN08_RS06065	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUN08_RS06070	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HUN08_RS06090	COG2239	Acts as a magnesium transporter
HUN08_RS06140	COG0598	Magnesium transport protein CorA
HUN08_RS06175	COG0435	Glutathione S-transferase
HUN08_RS06230	COG0018	arginyl-trna synthetase
HUN08_RS06235	COG0019	diaminopimelate decarboxylase activity
HUN08_RS06240	COG0460	homoserine dehydrogenase
HUN08_RS06245	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HUN08_RS06265	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HUN08_RS06270	COG0254	rRNA binding
HUN08_RS06275	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HUN08_RS06280	COG2890	protein-(glutamine-N5) methyltransferase activity
HUN08_RS06290	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HUN08_RS06305	COG0356	it plays a direct role in the translocation of protons across the membrane
HUN08_RS06310	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HUN08_RS06315	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HUN08_RS06320	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HUN08_RS06325	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HUN08_RS06390	COG0346	lactoylglutathione lyase activity
HUN08_RS06395	COG0183	Belongs to the thiolase family
HUN08_RS06400	COG2409	Drug exporters of the RND superfamily
HUN08_RS06410	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HUN08_RS06420	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HUN08_RS06435	COG3191	aminopeptidase activity
HUN08_RS06455	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HUN08_RS06465	COG1234	tRNA 3'-trailer cleavage
HUN08_RS06470	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HUN08_RS06475	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HUN08_RS06510	COG2890	protein-(glutamine-N5) methyltransferase activity
HUN08_RS06565	COG1376	ErfK ybiS ycfS ynhG family protein
HUN08_RS06575	COG1376	ErfK ybiS ycfS ynhG family protein
HUN08_RS06580	COG1960	acyl-CoA dehydrogenase activity
HUN08_RS06610	COG0456	acetyltransferase
HUN08_RS06615	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HUN08_RS06640	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HUN08_RS06645	COG1028	Short-chain dehydrogenase reductase Sdr
HUN08_RS06650	COG0446	pyridine nucleotide-disulphide oxidoreductase
HUN08_RS06650	COG1902	pentaerythritol trinitrate reductase activity
HUN08_RS06655	COG1695	Transcriptional regulator
HUN08_RS06685	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUN08_RS06690	COG1116	anion transmembrane transporter activity
HUN08_RS06700	COG0521	Mo-molybdopterin cofactor biosynthetic process
HUN08_RS06700	COG0315	cyclic pyranopterin monophosphate synthase activity
HUN08_RS06710	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HUN08_RS06730	COG2223	nitrite transmembrane transporter activity
HUN08_RS06755	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HUN08_RS06755	COG2146	nitrite reductase [NAD(P)H] activity
HUN08_RS06760	COG0746	molybdenum cofactor guanylyltransferase activity
HUN08_RS06765	COG0243	molybdopterin cofactor binding
HUN08_RS06770	COG1073	alpha beta
HUN08_RS06790	COG2015	COG2015, Alkyl sulfatase and related hydrolases
HUN08_RS06800	COG2902	Dehydrogenase
HUN08_RS06805	COG0824	Thioesterase
HUN08_RS06815	COG3177	Filamentation induced by cAMP protein fic
HUN08_RS06820	COG0366	Alpha amylase catalytic
HUN08_RS06840	COG0318	PFAM AMP-dependent synthetase and ligase
HUN08_RS06850	COG2072	flavoprotein involved in K transport
HUN08_RS06865	COG0406	alpha-ribazole phosphatase activity
HUN08_RS06900	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HUN08_RS06915	COG1301	dicarboxylic acid transport
HUN08_RS06935	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
HUN08_RS07125	COG3266	domain, Protein
HUN08_RS07130	COG1404	Belongs to the peptidase S8 family
HUN08_RS07140	COG1674	ftsk spoiiie
HUN08_RS07145	COG0464	growth
HUN08_RS07150	COG1376	ErfK ybiS ycfS ynhG family protein
HUN08_RS07165	COG0544	peptidyl-prolyl cis-trans isomerase activity
HUN08_RS07175	COG0740	serine-type endopeptidase activity
HUN08_RS07190	COG0525	valine-tRNA ligase activity
HUN08_RS07195	COG0285	dihydrofolate synthase activity
HUN08_RS07210	COG0105	UTP biosynthetic process
HUN08_RS07215	COG1530	ribonuclease E activity
HUN08_RS07215	COG1530	ribonuclease E activity
HUN08_RS07230	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HUN08_RS07235	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HUN08_RS07240	COG0742	ribosomal rna small subunit methyltransferase
HUN08_RS07265	COG0571	ribonuclease III activity
HUN08_RS07295	COG1254	Belongs to the acylphosphatase family
HUN08_RS07300	COG1196	nuclear chromosome segregation
HUN08_RS07315	COG0789	Transcriptional regulator
HUN08_RS07330	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
HUN08_RS07345	COG0228	four-way junction DNA binding
HUN08_RS07355	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HUN08_RS07360	COG0336	Belongs to the RNA methyltransferase TrmD family
HUN08_RS07375	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HUN08_RS07385	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HUN08_RS07390	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HUN08_RS07395	COG0406	alpha-ribazole phosphatase activity
HUN08_RS07435	COG4974	Belongs to the 'phage' integrase family
HUN08_RS07450	COG0052	Belongs to the universal ribosomal protein uS2 family
HUN08_RS07455	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HUN08_RS07460	COG0528	UMP kinase activity
HUN08_RS07465	COG0233	cytoplasmic translational termination
HUN08_RS07505	COG0820	rRNA (adenine-C2-)-methyltransferase activity
HUN08_RS07515	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HUN08_RS07520	COG0750	zinc metalloprotease
HUN08_RS07525	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HUN08_RS07540	COG0318	PFAM AMP-dependent synthetase and ligase
HUN08_RS07560	COG1492	cobalamin metabolic process
HUN08_RS07565	COG0596	Alpha beta hydrolase
HUN08_RS07575	COG0579	oxidoreductase
HUN08_RS07625	COG3022	response to hydroperoxide
HUN08_RS07630	COG0442	prolyl-tRNA aminoacylation
HUN08_RS07645	COG0779	Required for maturation of 30S ribosomal subunits
HUN08_RS07660	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HUN08_RS07665	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HUN08_RS07670	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
HUN08_RS07705	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HUN08_RS07710	COG1946	Acyl-CoA thioesterase
HUN08_RS07770	COG0183	Belongs to the thiolase family
HUN08_RS07785	COG1116	anion transmembrane transporter activity
HUN08_RS07825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUN08_RS07830	COG0765	amino acid transport
HUN08_RS07835	COG1126	abc transporter atp-binding protein
HUN08_RS07840	COG0473	3-isopropylmalate dehydrogenase activity
HUN08_RS07845	COG3467	pyridoxamine 5'-phosphate
HUN08_RS07850	COG1968	undecaprenyl-diphosphatase activity
HUN08_RS07855	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HUN08_RS07870	COG1528	Iron-storage protein
HUN08_RS07875	COG1335	isochorismatase
HUN08_RS07885	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HUN08_RS07885	COG0237	dephospho-CoA kinase activity
HUN08_RS07905	COG3973	AAA domain
HUN08_RS07915	COG3177	Filamentation induced by cAMP protein fic
HUN08_RS07920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUN08_RS07950	COG0291	Belongs to the bacterial ribosomal protein bL35 family
HUN08_RS07955	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HUN08_RS07975	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HUN08_RS07980	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HUN08_RS07980	COG0072	phenylalanine-tRNA ligase activity
HUN08_RS07995	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HUN08_RS08000	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HUN08_RS08005	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HUN08_RS08015	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HUN08_RS08025	COG0137	argininosuccinate synthase activity
HUN08_RS08030	COG0165	Argininosuccinate lyase
HUN08_RS08040	COG2835	tetraacyldisaccharide 4'-kinase activity
HUN08_RS08045	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HUN08_RS08065	COG0647	UMP catabolic process
HUN08_RS08080	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HUN08_RS08110	COG0504	CTP synthase activity
HUN08_RS08135	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HUN08_RS08145	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
HUN08_RS08150	COG1160	GTP binding
HUN08_RS08165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUN08_RS08170	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
HUN08_RS08205	COG1316	TRANSCRIPTIONal
HUN08_RS08210	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HUN08_RS08290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUN08_RS08315	COG1305	Transglutaminase-like
HUN08_RS08335	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HUN08_RS08345	COG0488	(ABC) transporter
HUN08_RS08360	COG1309	transcriptional regulator
HUN08_RS08365	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HUN08_RS08375	COG0791	NLP P60 protein
HUN08_RS08375	COG3883	PFAM NLP P60 protein
HUN08_RS08380	COG0714	Associated with various cellular activities
HUN08_RS08390	COG2304	oxidoreductase activity
HUN08_RS08400	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HUN08_RS08510	COG0569	domain protein
HUN08_RS08515	COG0531	amino acid
HUN08_RS08520	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HUN08_RS08525	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HUN08_RS08530	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
HUN08_RS08540	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HUN08_RS08555	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HUN08_RS08610	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HUN08_RS08620	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HUN08_RS08625	COG1560	Kdo2-lipid A biosynthetic process
HUN08_RS08630	COG0438	transferase activity, transferring glycosyl groups
HUN08_RS08640	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HUN08_RS08645	COG0631	protein serine/threonine phosphatase activity
HUN08_RS08660	COG1946	Acyl-CoA thioesterase
HUN08_RS08665	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HUN08_RS08675	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HUN08_RS08680	COG0632	four-way junction helicase activity
HUN08_RS08685	COG2255	four-way junction helicase activity
HUN08_RS08700	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HUN08_RS08705	COG0747	negative chemotaxis
HUN08_RS08715	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HUN08_RS08720	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HUN08_RS08755	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HUN08_RS08760	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HUN08_RS08765	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HUN08_RS08770	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HUN08_RS08780	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HUN08_RS08790	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HUN08_RS08800	COG0006	proline dipeptidase activity
HUN08_RS08805	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HUN08_RS08810	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HUN08_RS08815	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HUN08_RS08820	COG0540	Belongs to the ATCase OTCase family
HUN08_RS08835	COG0505	Belongs to the CarA family
HUN08_RS08845	COG0284	orotidine-5'-phosphate decarboxylase activity
HUN08_RS08860	COG0194	GDP metabolic process
HUN08_RS08865	COG1758	RNA polymerase activity
HUN08_RS08875	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HUN08_RS08915	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUN08_RS08915	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUN08_RS08920	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
HUN08_RS08935	COG0322	excinuclease ABC activity
HUN08_RS08955	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HUN08_RS08960	COG0126	phosphoglycerate kinase activity
HUN08_RS08965	COG0149	triose-phosphate isomerase activity
HUN08_RS08975	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HUN08_RS08980	COG0300	oxidoreductase activity
HUN08_RS08995	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HUN08_RS09010	COG2261	transglycosylase associated protein
HUN08_RS09040	COG2837	iron assimilation
HUN08_RS09045	COG2847	Copper chaperone PCu(A)C
HUN08_RS09115	COG1012	belongs to the aldehyde dehydrogenase family
HUN08_RS09140	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
HUN08_RS09145	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUN08_RS09175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUN08_RS09190	COG1914	H( )-stimulated, divalent metal cation uptake system
HUN08_RS09205	COG3104	oligopeptide transport
HUN08_RS09245	COG2267	carboxylic ester hydrolase activity
HUN08_RS09285	COG2241	protein methyltransferase activity
HUN08_RS09285	COG2242	protein methyltransferase activity
HUN08_RS09290	COG0300	oxidoreductase activity
HUN08_RS09335	COG1074	ATP-dependent DNA helicase activity
HUN08_RS09380	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HUN08_RS09390	COG1253	flavin adenine dinucleotide binding
HUN08_RS09405	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HUN08_RS09435	COG1716	ATPase activity
HUN08_RS09440	COG0509	glycine decarboxylation via glycine cleavage system
HUN08_RS09450	COG0653	protein targeting
HUN08_RS09465	COG1119	ATPase activity
HUN08_RS09475	COG2151	metal-sulfur cluster biosynthetic enzyme
HUN08_RS09480	COG0822	iron-sulfur transferase activity
HUN08_RS09490	COG0396	ATPase activity
HUN08_RS09515	COG1131	(ABC) transporter
HUN08_RS09540	COG0109	protoheme IX farnesyltransferase activity
HUN08_RS09550	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HUN08_RS09570	COG0318	PFAM AMP-dependent synthetase and ligase
HUN08_RS09615	COG0326	Molecular chaperone. Has ATPase activity
HUN08_RS09620	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HUN08_RS09650	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HUN08_RS09670	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
HUN08_RS09675	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
HUN08_RS09680	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
HUN08_RS09695	COG1222	aaa ATPase
HUN08_RS09710	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
HUN08_RS09740	COG1410	methionine synthase
HUN08_RS09740	COG0646	methionine synthase
HUN08_RS09755	COG0215	cysteine-tRNA ligase activity
HUN08_RS09775	COG1968	undecaprenyl-diphosphatase activity
HUN08_RS09865	COG0123	including yeast histone deacetylase and acetoin utilization protein
HUN08_RS09910	COG0450	alkyl hydroperoxide reductase
HUN08_RS09915	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUN08_RS09925	COG1643	Atp-dependent helicase
HUN08_RS09930	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HUN08_RS09940	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HUN08_RS09945	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HUN08_RS09950	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HUN08_RS09955	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HUN08_RS09965	COG1196	nuclear chromosome segregation
HUN08_RS09970	COG2329	Antibiotic biosynthesis monooxygenase
HUN08_RS09980	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HUN08_RS09985	COG1126	abc transporter atp-binding protein
HUN08_RS09990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUN08_RS09995	COG0765	amino acid transport
HUN08_RS10000	COG0765	amino acid transport
HUN08_RS10005	COG2137	regulation of response to DNA damage stimulus
HUN08_RS10010	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HUN08_RS10030	COG1396	sequence-specific DNA binding
HUN08_RS10035	COG1058	Belongs to the CinA family
HUN08_RS10035	COG1546	Belongs to the CinA family
HUN08_RS10045	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HUN08_RS10055	COG1674	ftsk spoiiie
HUN08_RS10060	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HUN08_RS10065	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUN08_RS10070	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
HUN08_RS10090	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HUN08_RS10095	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HUN08_RS10105	COG0477	Major facilitator Superfamily
HUN08_RS10145	COG0154	amidase activity
HUN08_RS10160	COG1185	polyribonucleotide nucleotidyltransferase activity
HUN08_RS10170	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUN08_RS10230	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HUN08_RS10235	COG0159	tryptophan synthase activity
HUN08_RS10245	COG0134	indole-3-glycerol-phosphate synthase activity
HUN08_RS10255	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HUN08_RS10265	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HUN08_RS10270	COG0107	imidazoleglycerol-phosphate synthase activity
HUN08_RS10275	COG0483	inositol monophosphate 1-phosphatase activity
HUN08_RS10290	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HUN08_RS10295	COG0131	Imidazoleglycerol-phosphate dehydratase
HUN08_RS10300	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HUN08_RS10305	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HUN08_RS10315	COG1012	belongs to the aldehyde dehydrogenase family
HUN08_RS10345	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HUN08_RS10350	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HUN08_RS10360	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HUN08_RS10415	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HUN08_RS10420	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HUN08_RS10440	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HUN08_RS10455	COG0252	asparaginase activity
HUN08_RS10465	COG5650	phosphatidylinositol metabolic process
HUN08_RS10475	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HUN08_RS10495	COG1799	cell septum assembly
HUN08_RS10505	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HUN08_RS10510	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HUN08_RS10515	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HUN08_RS10530	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HUN08_RS10535	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HUN08_RS10550	COG0768	penicillin binding
HUN08_RS10565	COG2001	Belongs to the MraZ family
HUN08_RS10595	COG0142	geranyltranstransferase activity
HUN08_RS10625	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
HUN08_RS10635	COG1051	belongs to the nudix hydrolase family
HUN08_RS10640	COG0204	Acyl-transferase
HUN08_RS10645	COG1940	carbohydrate kinase activity
HUN08_RS10675	COG0438	transferase activity, transferring glycosyl groups
HUN08_RS10690	COG0791	NLP P60 protein
HUN08_RS10690	COG0741	lytic transglycosylase activity
HUN08_RS10710	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HUN08_RS10715	COG1845	cytochrome c oxidase, subunit III
HUN08_RS10740	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HUN08_RS10755	COG0583	DNA-binding transcription factor activity
HUN08_RS10760	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUN08_RS10780	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
HUN08_RS10790	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HUN08_RS10795	COG0404	The glycine cleavage system catalyzes the degradation of glycine
HUN08_RS10800	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HUN08_RS10805	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUN08_RS10815	COG0321	lipoyl(octanoyl) transferase activity
HUN08_RS10820	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HUN08_RS10845	COG0174	glutamine synthetase
HUN08_RS10860	COG0477	Major facilitator Superfamily
HUN08_RS10885	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
HUN08_RS10890	COG0174	glutamine synthetase
HUN08_RS10895	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
HUN08_RS10905	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUN08_RS10940	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HUN08_RS11030	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HUN08_RS11050	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUN08_RS11085	COG0318	PFAM AMP-dependent synthetase and ligase
HUN08_RS11090	COG1024	Enoyl-CoA hydratase
HUN08_RS11135	COG1247	-acetyltransferase
HUN08_RS11155	COG0402	S-adenosylhomocysteine deaminase activity
HUN08_RS11165	COG0402	S-adenosylhomocysteine deaminase activity
HUN08_RS11205	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HUN08_RS11220	COG1802	Transcriptional regulator
HUN08_RS11265	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HUN08_RS11285	COG0385	Bile acid
HUN08_RS11290	COG0358	DNA primase activity
HUN08_RS11300	COG1278	Cold shock
HUN08_RS11310	COG0423	glycine-tRNA ligase activity
HUN08_RS11340	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HUN08_RS11345	COG1381	Involved in DNA repair and RecF pathway recombination
HUN08_RS11370	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HUN08_RS11390	COG0484	heat shock protein binding
HUN08_RS11395	COG1420	regulation of RNA biosynthetic process
HUN08_RS11415	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HUN08_RS11455	COG3842	ATPase activity
HUN08_RS11460	COG4208	sulfate ABC transporter
HUN08_RS11465	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HUN08_RS11480	COG0339	signal peptide processing
HUN08_RS11485	COG0481	GTPase activity
HUN08_RS11520	COG1555	photosystem II stabilization
HUN08_RS11520	COG1596	polysaccharide export
HUN08_RS11545	COG2755	lipolytic protein G-D-S-L family
HUN08_RS11555	COG0799	negative regulation of ribosome biogenesis
HUN08_RS11560	COG1113	amino acid transport
HUN08_RS11565	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HUN08_RS11575	COG0542	response to heat
HUN08_RS11580	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HUN08_RS11590	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUN08_RS11610	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HUN08_RS11620	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HUN08_RS11625	COG1024	Enoyl-CoA hydratase
HUN08_RS11645	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HUN08_RS11665	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
HUN08_RS11675	COG1920	GTP binding
HUN08_RS11695	COG0066	3-isopropylmalate dehydratase activity
HUN08_RS11700	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HUN08_RS11725	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HUN08_RS11735	COG0179	Fumarylacetoacetate (FAA) hydrolase
HUN08_RS11740	COG2271	Major facilitator Superfamily
HUN08_RS11745	COG0473	3-isopropylmalate dehydrogenase activity
HUN08_RS11760	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HUN08_RS11765	COG0440	acetolactate synthase activity
HUN08_RS11780	COG0129	dihydroxy-acid dehydratase activity
HUN08_RS11795	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HUN08_RS11840	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HUN08_RS11855	COG0482	sulfurtransferase activity
HUN08_RS11900	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HUN08_RS11920	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HUN08_RS11935	COG0110	maltose O-acetyltransferase activity
HUN08_RS11940	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HUN08_RS11955	COG1024	Enoyl-CoA hydratase
HUN08_RS11975	COG1119	ATPase activity
HUN08_RS11980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUN08_RS11985	COG3757	hydrolase, family 25
HUN08_RS11990	COG3757	hydrolase, family 25
HUN08_RS12000	COG0560	Phosphoserine phosphatase
HUN08_RS12000	COG3830	Belongs to the UPF0237 family
HUN08_RS12020	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HUN08_RS12070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUN08_RS12120	COG1482	cell wall glycoprotein biosynthetic process
HUN08_RS12150	COG0778	Nitroreductase
HUN08_RS12150	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
HUN08_RS12160	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HUN08_RS12165	COG2226	methyltransferase
HUN08_RS12180	COG0463	Glycosyl transferase, family 2
HUN08_RS12185	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HUN08_RS12190	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUN08_RS12195	COG1611	Belongs to the LOG family
HUN08_RS12200	COG1611	Belongs to the LOG family
HUN08_RS12215	COG4122	O-methyltransferase activity
HUN08_RS12235	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
HUN08_RS12245	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HUN08_RS12270	COG1177	transmembrane transport
HUN08_RS12395	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HUN08_RS12395	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HUN08_RS12740	COG0640	Transcriptional regulator
HUN08_RS12785	COG1309	transcriptional regulator
HUN08_RS12790	COG3119	arylsulfatase activity
HUN08_RS12795	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HUN08_RS12830	COG5290	Psort location Cytoplasmic, score
HUN08_RS12835	COG0012	GTP binding
HUN08_RS12845	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HUN08_RS12860	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HUN08_RS12900	COG1322	Protein conserved in bacteria
HUN08_RS12910	COG0439	Biotin carboxylase
HUN08_RS12945	COG0561	phosphatase activity
HUN08_RS12950	COG2066	Belongs to the glutaminase family
HUN08_RS12965	COG0477	Major facilitator Superfamily
HUN08_RS12995	COG3852	Histidine kinase
HUN08_RS13045	COG0033	Phosphoglucomutase
HUN08_RS13070	COG3119	arylsulfatase activity
HUN08_RS13090	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HUN08_RS13095	COG2177	Part of the ABC transporter FtsEX involved in
HUN08_RS13100	COG2884	Cell division ATP-binding protein ftsE
HUN08_RS13110	COG0668	transmembrane transport
HUN08_RS13115	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HUN08_RS13125	COG0483	inositol monophosphate 1-phosphatase activity
HUN08_RS13130	COG0069	glutamate synthase activity
HUN08_RS13165	COG1960	acyl-CoA dehydrogenase activity
HUN08_RS13285	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HUN08_RS13295	COG1595	DNA-templated transcription, initiation
HUN08_RS13345	COG2326	polyphosphate kinase activity
HUN08_RS13360	COG1615	UPF0182 protein
HUN08_RS13375	COG3480	Lon protease (S16) C-terminal proteolytic domain
HUN08_RS13390	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HUN08_RS13420	COG0210	DNA helicase
HUN08_RS13430	COG0596	Alpha beta hydrolase
HUN08_RS13465	COG1309	transcriptional regulator
HUN08_RS13495	COG0513	Belongs to the DEAD box helicase family
HUN08_RS13505	COG1192	Involved in chromosome partitioning
HUN08_RS13515	COG1597	lipid kinase activity
HUN08_RS13530	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HUN08_RS13545	COG2135	peptidase activity
HUN08_RS13575	COG0277	FAD linked oxidase domain protein
HUN08_RS13585	COG2261	transglycosylase associated protein
HUN08_RS13590	COG2814	Major facilitator Superfamily
HUN08_RS13620	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HUN08_RS13630	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HUN08_RS13635	COG1162	GTPase activity
HUN08_RS13690	COG0653	protein targeting
HUN08_RS13695	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HUN08_RS13705	COG5401	PFAM Sporulation and spore germination
HUN08_RS13710	COG5002	protein histidine kinase activity
HUN08_RS13745	COG0531	amino acid
HUN08_RS13805	COG0203	ribosomal protein L17
HUN08_RS13815	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HUN08_RS13820	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HUN08_RS13830	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HUN08_RS13835	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HUN08_RS13845	COG1100	Small GTP-binding protein
HUN08_RS13885	COG1950	PFAM Membrane protein of
HUN08_RS13900	COG1490	D-aminoacyl-tRNA deacylase activity
HUN08_RS13910	COG0563	adenylate kinase activity
HUN08_RS13930	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HUN08_RS13935	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HUN08_RS13940	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HUN08_RS13945	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HUN08_RS13955	COG1140	nitrate reductase beta subunit
HUN08_RS13980	COG0604	alcohol dehydrogenase
HUN08_RS14015	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HUN08_RS14025	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HUN08_RS14030	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HUN08_RS14055	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUN08_RS14085	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUN08_RS14090	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HUN08_RS14105	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HUN08_RS14110	COG0255	Belongs to the universal ribosomal protein uL29 family
HUN08_RS14115	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HUN08_RS14120	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HUN08_RS14130	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HUN08_RS14135	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HUN08_RS14145	COG0088	Forms part of the polypeptide exit tunnel
HUN08_RS14150	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HUN08_RS14155	COG0051	transcription antitermination factor activity, RNA binding
HUN08_RS14235	COG0535	radical SAM domain protein
HUN08_RS14295	COG4221	oxidoreductase activity
HUN08_RS14320	COG4948	Mandelate Racemase Muconate Lactonizing
HUN08_RS14350	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HUN08_RS14355	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HUN08_RS14360	COG0049	tRNA binding
HUN08_RS14365	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HUN08_RS14390	COG0574	Belongs to the PEP-utilizing enzyme family
HUN08_RS14390	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HUN08_RS14395	COG1012	belongs to the aldehyde dehydrogenase family
HUN08_RS14395	COG1454	alcohol dehydrogenase
HUN08_RS14440	COG0708	Exodeoxyribonuclease III
HUN08_RS14445	COG2186	Transcriptional regulator
HUN08_RS14450	COG2807	transmembrane transport
HUN08_RS14460	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
HUN08_RS14465	COG2890	protein-(glutamine-N5) methyltransferase activity
HUN08_RS14485	COG1309	transcriptional regulator
HUN08_RS14490	COG1024	Enoyl-CoA hydratase
HUN08_RS14505	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUN08_RS14530	COG0640	Transcriptional regulator
HUN08_RS14570	COG0300	oxidoreductase activity
HUN08_RS14630	COG3321	synthase
HUN08_RS14630	COG1028	Short-chain dehydrogenase reductase Sdr
HUN08_RS14630	COG0604	alcohol dehydrogenase
HUN08_RS14640	COG3214	Protein conserved in bacteria
HUN08_RS14655	COG2226	methyltransferase
HUN08_RS14660	COG0438	transferase activity, transferring glycosyl groups
HUN08_RS14675	COG1994	Peptidase M50
HUN08_RS14680	COG1733	regulation of RNA biosynthetic process
HUN08_RS14720	COG0406	alpha-ribazole phosphatase activity
HUN08_RS14735	COG3422	double-strand break repair
HUN08_RS14760	COG2801	Transposase and inactivated derivatives
HUN08_RS14760	COG3415	Transposase
HUN08_RS14780	COG1960	acyl-CoA dehydrogenase activity
HUN08_RS14790	COG0697	spore germination
HUN08_RS14840	COG0783	Belongs to the Dps family
HUN08_RS14870	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HUN08_RS14875	COG0085	RNA polymerase activity
HUN08_RS14920	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HUN08_RS14925	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HUN08_RS14935	COG0222	ribosome binding
HUN08_RS14955	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HUN08_RS15020	COG0081	regulation of translation
HUN08_RS15025	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HUN08_RS15045	COG2030	dehydratase
HUN08_RS15050	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HUN08_RS15070	COG1666	GTP binding
HUN08_RS15075	COG3415	Transposase
HUN08_RS15075	COG2801	Transposase and inactivated derivatives
HUN08_RS15080	COG0501	Belongs to the peptidase M48B family
HUN08_RS15090	COG0644	oxidoreductase
HUN08_RS15100	COG2226	methyltransferase
HUN08_RS15105	COG0438	transferase activity, transferring glycosyl groups
HUN08_RS15115	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HUN08_RS15125	COG2226	methyltransferase
HUN08_RS15130	COG3268	Saccharopine dehydrogenase
HUN08_RS15150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUN08_RS15200	COG3415	Transposase
HUN08_RS15200	COG2801	Transposase and inactivated derivatives
HUN08_RS15210	COG1136	(ABC) transporter
HUN08_RS15235	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HUN08_RS15245	COG0785	Cytochrome C biogenesis protein
HUN08_RS15250	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HUN08_RS15255	COG0406	alpha-ribazole phosphatase activity
HUN08_RS15260	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HUN08_RS15265	COG2755	lipolytic protein G-D-S-L family
HUN08_RS15275	COG1473	amidohydrolase
HUN08_RS15300	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
HUN08_RS15305	COG1648	precorrin-2 dehydrogenase activity
HUN08_RS15305	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HUN08_RS15310	COG0181	hydroxymethylbilane synthase activity
HUN08_RS15315	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HUN08_RS15320	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HUN08_RS15415	COG5002	protein histidine kinase activity
HUN08_RS15425	COG0588	phosphoglycerate mutase activity
HUN08_RS15435	COG0438	transferase activity, transferring glycosyl groups
HUN08_RS15440	COG5650	phosphatidylinositol metabolic process
HUN08_RS15460	COG1121	(ABC) transporter
HUN08_RS15465	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HUN08_RS15480	COG2272	Belongs to the type-B carboxylesterase lipase family
HUN08_RS15495	COG0215	cysteine-tRNA ligase activity
HUN08_RS15505	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
HUN08_RS15510	COG1329	Transcriptional regulator
HUN08_RS15515	COG2847	Copper chaperone PCu(A)C
HUN08_RS15520	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HUN08_RS15530	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HUN08_RS15545	COG1194	a g-specific adenine glycosylase
HUN08_RS15605	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HUN08_RS15615	COG1028	Short-chain dehydrogenase reductase Sdr
HUN08_RS15625	COG1960	acyl-CoA dehydrogenase activity
HUN08_RS15630	COG1960	acyl-CoA dehydrogenase activity
HUN08_RS15635	COG0318	PFAM AMP-dependent synthetase and ligase
HUN08_RS15640	COG3284	Transcriptional regulator
HUN08_RS15645	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUN08_RS15655	COG1012	belongs to the aldehyde dehydrogenase family
HUN08_RS15670	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUN08_RS15680	COG1024	Enoyl-CoA hydratase
HUN08_RS15685	COG1028	Short-chain dehydrogenase reductase Sdr
HUN08_RS15715	COG0739	heme binding
HUN08_RS15730	COG2070	2-Nitropropane dioxygenase
HUN08_RS15740	COG1024	Enoyl-CoA hydratase
HUN08_RS15790	COG1285	pathogenesis
HUN08_RS15815	COG1595	DNA-templated transcription, initiation
HUN08_RS15820	COG1252	NADH dehydrogenase
HUN08_RS15835	COG2124	cytochrome p450
HUN08_RS15840	COG0183	Belongs to the thiolase family
HUN08_RS15865	COG2124	cytochrome p450
HUN08_RS15875	COG0318	PFAM AMP-dependent synthetase and ligase
HUN08_RS15885	COG1028	Short-chain dehydrogenase reductase Sdr
HUN08_RS15895	COG1024	Enoyl-CoA hydratase
HUN08_RS15915	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUN08_RS15930	COG2813	Specifically methylates the guanine in position
HUN08_RS15935	COG2814	Major facilitator Superfamily
HUN08_RS15945	COG1309	transcriptional regulator
HUN08_RS15960	COG1012	belongs to the aldehyde dehydrogenase family
HUN08_RS15965	COG0183	Belongs to the thiolase family
HUN08_RS15975	COG1960	acyl-CoA dehydrogenase activity
HUN08_RS15980	COG0318	PFAM AMP-dependent synthetase and ligase
HUN08_RS16005	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HUN08_RS16030	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HUN08_RS16035	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HUN08_RS16040	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HUN08_RS16080	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HUN08_RS16095	COG0037	tRNA processing
HUN08_RS16105	COG2027	D-alanyl-D-alanine carboxypeptidase
HUN08_RS16115	COG1169	isochorismate synthase
HUN08_RS16160	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HUN08_RS16185	COG4129	membrane
HUN08_RS16190	COG0390	transport system, permease component
HUN08_RS16210	COG0586	Pfam SNARE associated Golgi protein
HUN08_RS16215	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUN08_RS16230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUN08_RS16245	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
HUN08_RS16250	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HUN08_RS16265	COG0542	response to heat
HUN08_RS16300	COG0318	PFAM AMP-dependent synthetase and ligase
HUN08_RS16340	COG0789	Transcriptional regulator
HUN08_RS16345	COG0484	heat shock protein binding
HUN08_RS16350	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HUN08_RS16355	COG0443	Heat shock 70 kDa protein
HUN08_RS16415	COG0247	lactate metabolic process
HUN08_RS16415	COG2181	nitrate reductase activity
HUN08_RS16455	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HUN08_RS16460	COG2271	Major facilitator Superfamily
HUN08_RS16470	COG0039	L-malate dehydrogenase activity
HUN08_RS16475	COG0300	oxidoreductase activity
HUN08_RS16520	COG0738	Major facilitator superfamily
HUN08_RS16570	COG1073	alpha beta
HUN08_RS16575	COG2211	Major facilitator Superfamily
HUN08_RS16605	COG0604	alcohol dehydrogenase
HUN08_RS16610	COG1733	regulation of RNA biosynthetic process
HUN08_RS16620	COG1872	DUF167
HUN08_RS16625	COG2818	Glycosylase
HUN08_RS16640	COG4424	Sulfotransferase
HUN08_RS16645	COG3119	arylsulfatase activity
HUN08_RS16680	COG0701	Predicted permease
HUN08_RS16695	COG2197	response regulator
HUN08_RS16725	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HUN08_RS16755	COG1742	UPF0060 membrane protein
HUN08_RS16765	COG1960	acyl-CoA dehydrogenase activity
HUN08_RS16780	COG0076	glutamate decarboxylase activity
HUN08_RS16800	COG1028	Short-chain dehydrogenase reductase Sdr
HUN08_RS16805	COG2030	dehydratase
HUN08_RS16815	COG1472	Belongs to the glycosyl hydrolase 3 family
HUN08_RS16820	COG4981	capsule polysaccharide biosynthetic process
HUN08_RS16870	COG3552	Protein containing von Willebrand factor type A (VWA) domain
HUN08_RS16880	COG0714	Associated with various cellular activities
HUN08_RS16885	COG3831	ATPase activity
HUN08_RS16895	COG1260	myo-inositol-1-phosphate synthase
HUN08_RS16900	COG1695	Transcriptional regulator
HUN08_RS16910	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HUN08_RS16935	COG3654	unkown
HUN08_RS16960	COG0359	binds to the 23S rRNA
HUN08_RS16970	COG0305	Participates in initiation and elongation during chromosome replication
HUN08_RS17005	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HUN08_RS17075	COG1484	DNA-dependent DNA replication
HUN08_RS17110	COG1012	belongs to the aldehyde dehydrogenase family
HUN08_RS17115	COG4221	oxidoreductase activity
HUN08_RS17125	COG0318	PFAM AMP-dependent synthetase and ligase
HUN08_RS17140	COG0477	Major facilitator Superfamily
HUN08_RS17180	COG1733	regulation of RNA biosynthetic process
HUN08_RS17200	COG0583	DNA-binding transcription factor activity
HUN08_RS17240	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HUN08_RS17245	COG0318	PFAM AMP-dependent synthetase and ligase
HUN08_RS17260	COG0438	transferase activity, transferring glycosyl groups
HUN08_RS17300	COG1024	Enoyl-CoA hydratase
HUN08_RS17300	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUN08_RS17305	COG0183	Belongs to the thiolase family
HUN08_RS17310	COG1309	transcriptional regulator
HUN08_RS17315	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
HUN08_RS17335	COG0110	maltose O-acetyltransferase activity
HUN08_RS17350	COG1960	acyl-CoA dehydrogenase activity
HUN08_RS17375	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUN08_RS17385	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUN08_RS17395	COG1063	alcohol dehydrogenase
HUN08_RS17400	COG2070	2-Nitropropane dioxygenase
HUN08_RS17405	COG0183	Belongs to the thiolase family
HUN08_RS17415	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUN08_RS17420	COG2827	Endonuclease containing a URI domain
HUN08_RS17425	COG1012	belongs to the aldehyde dehydrogenase family
HUN08_RS17435	COG1309	transcriptional regulator
HUN08_RS17450	COG1960	acyl-CoA dehydrogenase activity
HUN08_RS17460	COG1012	belongs to the aldehyde dehydrogenase family
HUN08_RS17470	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUN08_RS17475	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUN08_RS17480	COG1960	acyl-CoA dehydrogenase activity
HUN08_RS17485	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUN08_RS17495	COG1960	acyl-CoA dehydrogenase activity
HUN08_RS17500	COG2301	Belongs to the HpcH HpaI aldolase family
HUN08_RS17510	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
HUN08_RS17555	COG0183	Belongs to the thiolase family
HUN08_RS17560	COG1960	acyl-CoA dehydrogenase activity
HUN08_RS17580	COG3284	Transcriptional regulator
HUN08_RS17590	COG2079	MmgE PrpD family protein
HUN08_RS17610	COG1129	ABC transporter
HUN08_RS17635	COG2197	response regulator
HUN08_RS17640	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HUN08_RS17645	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HUN08_RS17675	COG2855	membrane
HUN08_RS17695	COG2072	flavoprotein involved in K transport
HUN08_RS17725	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HUN08_RS17730	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HUN08_RS17785	COG3976	FMN-binding domain protein
HUN08_RS17785	COG1053	succinate dehydrogenase
HUN08_RS17795	COG1937	Protein conserved in bacteria
HUN08_RS17830	COG2119	membrane
HUN08_RS17835	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
HUN08_RS17860	COG2837	iron assimilation
HUN08_RS17890	COG1960	acyl-CoA dehydrogenase activity
HUN08_RS17915	COG0714	Associated with various cellular activities
HUN08_RS17935	COG3631	Ketosteroid isomerase-related protein
HUN08_RS17940	COG4221	oxidoreductase activity
HUN08_RS17955	COG1846	Transcriptional regulator
HUN08_RS17960	COG2814	Major facilitator Superfamily
HUN08_RS17975	COG0577	efflux transmembrane transporter activity
HUN08_RS17975	COG1136	(ABC) transporter
HUN08_RS17980	COG1136	(ABC) transporter
HUN08_RS17980	COG0577	efflux transmembrane transporter activity
HUN08_RS17985	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
HUN08_RS18000	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HUN08_RS18015	COG2197	response regulator
HUN08_RS18020	COG4585	Histidine kinase
HUN08_RS18050	COG3590	peptidase
HUN08_RS18090	COG0328	RNA-DNA hybrid ribonuclease activity
HUN08_RS18095	COG4106	trans-aconitate 2-methyltransferase activity
HUN08_RS18110	COG0495	leucyl-tRNA aminoacylation
HUN08_RS18135	COG1678	Uncharacterized ACR, COG1678
HUN08_RS18145	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HUN08_RS18155	COG3304	Inner membrane component domain
HUN08_RS18180	COG0617	tRNA 3'-terminal CCA addition
HUN08_RS18200	COG1595	DNA-templated transcription, initiation
HUN08_RS18220	COG0860	N-Acetylmuramoyl-L-alanine amidase
HUN08_RS18220	COG3409	Peptidoglycan-binding domain 1 protein
HUN08_RS18235	COG1192	Involved in chromosome partitioning
HUN08_RS18240	COG0357	Ribosomal RNA small subunit methyltransferase G
HUN08_RS18250	COG0706	membrane insertase activity
HUN08_RS18255	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
HUN08_RS18260	COG0594	ribonuclease P activity
HUN08_RS18265	COG0230	Belongs to the bacterial ribosomal protein bL34 family