GBCGDNIH2_RS08720 070b9cef0df03f2a7f22f05af98707bd 237 SMART SM00862 150 225 9.3E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 GBCGDNIH2_RS08720 070b9cef0df03f2a7f22f05af98707bd 237 Pfam PF00072 Response regulator receiver domain 8 118 5.0E-21 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GBCGDNIH2_RS08720 070b9cef0df03f2a7f22f05af98707bd 237 Gene3D G3DSA:3.40.50.2300 2 124 5.8E-30 T 29-03-2018 GBCGDNIH2_RS08720 070b9cef0df03f2a7f22f05af98707bd 237 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 225 5.3E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 GBCGDNIH2_RS08720 070b9cef0df03f2a7f22f05af98707bd 237 Gene3D G3DSA:1.10.10.10 125 232 3.0E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS08720 070b9cef0df03f2a7f22f05af98707bd 237 SMART SM00448 6 117 5.1E-32 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GBCGDNIH2_RS08720 070b9cef0df03f2a7f22f05af98707bd 237 SUPERFAMILY SSF52172 4 177 6.64E-36 T 29-03-2018 IPR011006 CheY-like superfamily GBCGDNIH2_RS09650 eb4280a24567f49ae8bdb9b8b4fd6240 559 Pfam PF01494 FAD binding domain 100 130 2.9E-5 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 GBCGDNIH2_RS09650 eb4280a24567f49ae8bdb9b8b4fd6240 559 PIRSF PIRSF038984 1 543 2.3E-231 T 29-03-2018 IPR028348 FAD dependent protein GBCGDNIH2_RS09650 eb4280a24567f49ae8bdb9b8b4fd6240 559 SUPERFAMILY SSF51905 100 291 6.15E-33 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS09650 eb4280a24567f49ae8bdb9b8b4fd6240 559 SUPERFAMILY SSF51905 485 536 6.15E-33 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS09650 eb4280a24567f49ae8bdb9b8b4fd6240 559 Gene3D G3DSA:3.50.50.60 85 540 7.5E-46 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS10090 35f94a07dfae2a192b8b2c832f254415 518 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 145 316 5.6E-47 T 29-03-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS10090 35f94a07dfae2a192b8b2c832f254415 518 SUPERFAMILY SSF142019 97 337 5.23E-89 T 29-03-2018 GBCGDNIH2_RS10090 35f94a07dfae2a192b8b2c832f254415 518 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 264 279 - T 29-03-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS10090 35f94a07dfae2a192b8b2c832f254415 518 SMART SM00928 426 471 5.2E-19 T 29-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS10090 35f94a07dfae2a192b8b2c832f254415 518 SUPERFAMILY SSF140490 423 511 2.48E-30 T 29-03-2018 GBCGDNIH2_RS10090 35f94a07dfae2a192b8b2c832f254415 518 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 439 450 - T 29-03-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS10090 35f94a07dfae2a192b8b2c832f254415 518 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 428 509 8.0E-31 T 29-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS10090 35f94a07dfae2a192b8b2c832f254415 518 SUPERFAMILY SSF142984 340 421 3.4E-19 T 29-03-2018 GBCGDNIH2_RS08620 9928c97ebd6a141d72a6718ac5b33b45 304 Gene3D G3DSA:3.40.190.10 88 177 6.8E-15 T 29-03-2018 GBCGDNIH2_RS08620 9928c97ebd6a141d72a6718ac5b33b45 304 Gene3D G3DSA:1.10.10.10 1 84 3.8E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS08620 9928c97ebd6a141d72a6718ac5b33b45 304 SUPERFAMILY SSF46785 3 110 3.1E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS08620 9928c97ebd6a141d72a6718ac5b33b45 304 Gene3D G3DSA:3.40.190.10 178 271 4.6E-12 T 29-03-2018 GBCGDNIH2_RS08620 9928c97ebd6a141d72a6718ac5b33b45 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 5.0E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS08620 9928c97ebd6a141d72a6718ac5b33b45 304 SUPERFAMILY SSF53850 91 299 2.9E-27 T 29-03-2018 GBCGDNIH2_RS08620 9928c97ebd6a141d72a6718ac5b33b45 304 Pfam PF03466 LysR substrate binding domain 89 297 1.3E-26 T 29-03-2018 IPR005119 LysR, substrate-binding GBCGDNIH2_RS10380 648adcd677c7cf6e941a0b0c1060027f 537 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 238 265 6.7E-6 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 GBCGDNIH2_RS10380 648adcd677c7cf6e941a0b0c1060027f 537 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 507 533 4.9E-4 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 GBCGDNIH2_RS10380 648adcd677c7cf6e941a0b0c1060027f 537 Gene3D G3DSA:3.40.50.300 278 534 2.4E-72 T 29-03-2018 GBCGDNIH2_RS10380 648adcd677c7cf6e941a0b0c1060027f 537 Gene3D G3DSA:3.40.50.300 13 268 7.5E-63 T 29-03-2018 GBCGDNIH2_RS10380 648adcd677c7cf6e941a0b0c1060027f 537 SUPERFAMILY SSF52540 9 263 2.57E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS10380 648adcd677c7cf6e941a0b0c1060027f 537 Pfam PF00005 ABC transporter 305 456 6.2E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GBCGDNIH2_RS10380 648adcd677c7cf6e941a0b0c1060027f 537 Pfam PF00005 ABC transporter 33 186 3.4E-24 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GBCGDNIH2_RS10380 648adcd677c7cf6e941a0b0c1060027f 537 SMART SM00382 41 236 4.1E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS10380 648adcd677c7cf6e941a0b0c1060027f 537 SMART SM00382 313 505 1.2E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS10380 648adcd677c7cf6e941a0b0c1060027f 537 SUPERFAMILY SSF52540 280 527 1.42E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS10380 648adcd677c7cf6e941a0b0c1060027f 537 ProSitePatterns PS00211 ABC transporters family signature. 428 442 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GBCGDNIH2_RS10380 648adcd677c7cf6e941a0b0c1060027f 537 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GBCGDNIH2_RS06470 9745fb466c5c17b269011084d96d5ca1 247 SUPERFAMILY SSF52540 4 224 1.2E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS06470 9745fb466c5c17b269011084d96d5ca1 247 SMART SM00382 29 219 6.8E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS06470 9745fb466c5c17b269011084d96d5ca1 247 Gene3D G3DSA:3.40.50.300 1 246 3.2E-60 T 29-03-2018 GBCGDNIH2_RS06470 9745fb466c5c17b269011084d96d5ca1 247 Pfam PF00005 ABC transporter 21 163 4.1E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GBCGDNIH2_RS06410 9dd937c68a8ee65f54558abc2bbe9b15 162 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 10 133 2.9E-35 T 29-03-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 GBCGDNIH2_RS06410 9dd937c68a8ee65f54558abc2bbe9b15 162 Gene3D G3DSA:3.30.530.20 1 143 1.2E-38 T 29-03-2018 IPR023393 START-like domain GBCGDNIH2_RS06410 9dd937c68a8ee65f54558abc2bbe9b15 162 SUPERFAMILY SSF55961 1 141 2.65E-37 T 29-03-2018 GBCGDNIH2_RS05200 a3d8a3de252ad6bfccb3b372d82caf1f 476 ProSitePatterns PS00180 Glutamine synthetase signature 1. 58 76 - T 29-03-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 GBCGDNIH2_RS05200 a3d8a3de252ad6bfccb3b372d82caf1f 476 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 266 281 - T 29-03-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 GBCGDNIH2_RS05200 a3d8a3de252ad6bfccb3b372d82caf1f 476 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 13 475 4.0E-196 T 29-03-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 GBCGDNIH2_RS05200 a3d8a3de252ad6bfccb3b372d82caf1f 476 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 23 103 8.8E-30 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 GBCGDNIH2_RS05200 a3d8a3de252ad6bfccb3b372d82caf1f 476 Gene3D G3DSA:3.30.590.10 113 465 6.8E-115 T 29-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 GBCGDNIH2_RS05200 a3d8a3de252ad6bfccb3b372d82caf1f 476 SUPERFAMILY SSF54368 11 109 1.14E-35 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 GBCGDNIH2_RS05200 a3d8a3de252ad6bfccb3b372d82caf1f 476 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 393 405 - T 29-03-2018 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 GBCGDNIH2_RS05200 a3d8a3de252ad6bfccb3b372d82caf1f 476 Pfam PF00120 Glutamine synthetase, catalytic domain 111 473 4.6E-133 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 GBCGDNIH2_RS05200 a3d8a3de252ad6bfccb3b372d82caf1f 476 SUPERFAMILY SSF55931 111 475 7.06E-130 T 29-03-2018 GBCGDNIH2_RS05200 a3d8a3de252ad6bfccb3b372d82caf1f 476 Gene3D G3DSA:3.10.20.70 10 112 5.5E-27 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 GBCGDNIH2_RS05200 a3d8a3de252ad6bfccb3b372d82caf1f 476 SMART SM01230 110 386 6.1E-133 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 GBCGDNIH2_RS00115 669ea3bbb863d96db1cfa83dbe711b69 226 PRINTS PR00773 GrpE protein signature 177 192 9.3E-17 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 GBCGDNIH2_RS00115 669ea3bbb863d96db1cfa83dbe711b69 226 PRINTS PR00773 GrpE protein signature 90 106 9.3E-17 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 GBCGDNIH2_RS00115 669ea3bbb863d96db1cfa83dbe711b69 226 PRINTS PR00773 GrpE protein signature 204 223 9.3E-17 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 GBCGDNIH2_RS00115 669ea3bbb863d96db1cfa83dbe711b69 226 PRINTS PR00773 GrpE protein signature 118 133 9.3E-17 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 GBCGDNIH2_RS00115 669ea3bbb863d96db1cfa83dbe711b69 226 SUPERFAMILY SSF58014 69 169 2.62E-19 T 29-03-2018 GBCGDNIH2_RS00115 669ea3bbb863d96db1cfa83dbe711b69 226 Gene3D G3DSA:3.90.20.20 34 168 4.9E-20 T 29-03-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 GBCGDNIH2_RS00115 669ea3bbb863d96db1cfa83dbe711b69 226 Pfam PF01025 GrpE 57 225 1.0E-44 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 GBCGDNIH2_RS00115 669ea3bbb863d96db1cfa83dbe711b69 226 Hamap MF_01151 Protein GrpE [grpE]. 35 225 16.758 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 GBCGDNIH2_RS00115 669ea3bbb863d96db1cfa83dbe711b69 226 Gene3D G3DSA:2.30.22.10 169 225 9.5E-17 T 29-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 GBCGDNIH2_RS00115 669ea3bbb863d96db1cfa83dbe711b69 226 SUPERFAMILY SSF51064 173 225 1.31E-14 T 29-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 GBCGDNIH2_RS07575 e40309a4bdb72bfe494a5fa24932c41e 811 SMART SM00044 575 790 0.0094 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 GBCGDNIH2_RS07575 e40309a4bdb72bfe494a5fa24932c41e 811 SUPERFAMILY SSF55781 448 573 9.48E-10 T 29-03-2018 IPR029016 GAF domain-like GBCGDNIH2_RS07575 e40309a4bdb72bfe494a5fa24932c41e 811 Gene3D G3DSA:3.30.450.40 441 584 4.1E-10 T 29-03-2018 IPR029016 GAF domain-like GBCGDNIH2_RS07575 e40309a4bdb72bfe494a5fa24932c41e 811 SUPERFAMILY SSF55073 647 797 1.0E-19 T 29-03-2018 IPR029787 Nucleotide cyclase GBCGDNIH2_RS07575 e40309a4bdb72bfe494a5fa24932c41e 811 Gene3D G3DSA:3.30.450.20 249 379 3.0E-11 T 29-03-2018 GBCGDNIH2_RS07575 e40309a4bdb72bfe494a5fa24932c41e 811 Pfam PF02743 Cache domain 88 367 1.4E-23 T 29-03-2018 IPR033479 Double Cache domain 1 GBCGDNIH2_RS07575 e40309a4bdb72bfe494a5fa24932c41e 811 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 646 795 3.4E-14 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 GBCGDNIH2_RS07575 e40309a4bdb72bfe494a5fa24932c41e 811 Gene3D G3DSA:3.30.450.20 129 248 3.3E-15 T 29-03-2018 GBCGDNIH2_RS07575 e40309a4bdb72bfe494a5fa24932c41e 811 Gene3D G3DSA:3.30.70.1230 635 811 1.6E-18 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 GBCGDNIH2_RS00440 0b98a33d1c4873e43c9bd97ce1d626e2 200 Gene3D G3DSA:1.10.286.10 10 58 7.3E-21 T 29-03-2018 GBCGDNIH2_RS00440 0b98a33d1c4873e43c9bd97ce1d626e2 200 Gene3D G3DSA:3.30.1130.10 59 193 6.0E-53 T 29-03-2018 GBCGDNIH2_RS00440 0b98a33d1c4873e43c9bd97ce1d626e2 200 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 13 191 2.9E-64 T 29-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 GBCGDNIH2_RS00440 0b98a33d1c4873e43c9bd97ce1d626e2 200 Pfam PF01227 GTP cyclohydrolase I 13 190 3.4E-74 T 29-03-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 GBCGDNIH2_RS00440 0b98a33d1c4873e43c9bd97ce1d626e2 200 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 8 191 37.857 T 29-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 GBCGDNIH2_RS00440 0b98a33d1c4873e43c9bd97ce1d626e2 200 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 70 86 - T 29-03-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 GBCGDNIH2_RS00440 0b98a33d1c4873e43c9bd97ce1d626e2 200 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 118 128 - T 29-03-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 GBCGDNIH2_RS00440 0b98a33d1c4873e43c9bd97ce1d626e2 200 SUPERFAMILY SSF55620 4 191 1.56E-73 T 29-03-2018 GBCGDNIH2_RS11230 aee876fe52dbda9e6b124304abfc1692 100 TIGRFAM TIGR00193 urease_gam: urease, gamma subunit 1 100 4.3E-49 T 29-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 GBCGDNIH2_RS11230 aee876fe52dbda9e6b124304abfc1692 100 SUPERFAMILY SSF54111 1 100 3.92E-46 T 29-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 GBCGDNIH2_RS11230 aee876fe52dbda9e6b124304abfc1692 100 Pfam PF00547 Urease, gamma subunit 1 99 1.9E-48 T 29-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 GBCGDNIH2_RS11230 aee876fe52dbda9e6b124304abfc1692 100 PIRSF PIRSF001223 1 100 1.1E-51 T 29-03-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 GBCGDNIH2_RS11230 aee876fe52dbda9e6b124304abfc1692 100 Hamap MF_00739 Urease subunit gamma [ureA]. 1 100 34.944 T 29-03-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 GBCGDNIH2_RS11230 aee876fe52dbda9e6b124304abfc1692 100 ProDom PD002319 SUBUNIT GAMMA HYDROLASE UREASE UREA AMIDOHYDROLASE UREASE ALPHA GAMMA/BETA METAL-BINDING 9 99 3.0E-40 T 29-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 GBCGDNIH2_RS11230 aee876fe52dbda9e6b124304abfc1692 100 Gene3D G3DSA:3.30.280.10 2 99 2.2E-49 T 29-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 GBCGDNIH2_RS02090 6fc5a3e25ca9fedf972084cb38d53706 897 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 20 893 0.0 T 29-03-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 GBCGDNIH2_RS02090 6fc5a3e25ca9fedf972084cb38d53706 897 SUPERFAMILY SSF53732 7 628 4.19E-226 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 GBCGDNIH2_RS02090 6fc5a3e25ca9fedf972084cb38d53706 897 PRINTS PR00415 Aconitase family signature 148 161 1.1E-40 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 GBCGDNIH2_RS02090 6fc5a3e25ca9fedf972084cb38d53706 897 PRINTS PR00415 Aconitase family signature 281 294 1.1E-40 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 GBCGDNIH2_RS02090 6fc5a3e25ca9fedf972084cb38d53706 897 PRINTS PR00415 Aconitase family signature 295 308 1.1E-40 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 GBCGDNIH2_RS02090 6fc5a3e25ca9fedf972084cb38d53706 897 PRINTS PR00415 Aconitase family signature 495 508 1.1E-40 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 GBCGDNIH2_RS02090 6fc5a3e25ca9fedf972084cb38d53706 897 PRINTS PR00415 Aconitase family signature 172 180 1.1E-40 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 GBCGDNIH2_RS02090 6fc5a3e25ca9fedf972084cb38d53706 897 PRINTS PR00415 Aconitase family signature 205 218 1.1E-40 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 GBCGDNIH2_RS02090 6fc5a3e25ca9fedf972084cb38d53706 897 PRINTS PR00415 Aconitase family signature 219 234 1.1E-40 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 GBCGDNIH2_RS02090 6fc5a3e25ca9fedf972084cb38d53706 897 PRINTS PR00415 Aconitase family signature 433 444 1.1E-40 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 GBCGDNIH2_RS02090 6fc5a3e25ca9fedf972084cb38d53706 897 PRINTS PR00415 Aconitase family signature 375 389 1.1E-40 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 GBCGDNIH2_RS02090 6fc5a3e25ca9fedf972084cb38d53706 897 ProSitePatterns PS00450 Aconitase family signature 1. 429 445 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 GBCGDNIH2_RS02090 6fc5a3e25ca9fedf972084cb38d53706 897 SUPERFAMILY SSF52016 634 892 6.08E-91 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel GBCGDNIH2_RS02090 6fc5a3e25ca9fedf972084cb38d53706 897 Gene3D G3DSA:3.30.499.10 375 578 7.3E-65 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 GBCGDNIH2_RS02090 6fc5a3e25ca9fedf972084cb38d53706 897 Gene3D G3DSA:3.30.499.10 25 241 1.1E-75 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 GBCGDNIH2_RS02090 6fc5a3e25ca9fedf972084cb38d53706 897 Gene3D G3DSA:3.20.19.10 657 895 2.7E-90 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel GBCGDNIH2_RS02090 6fc5a3e25ca9fedf972084cb38d53706 897 ProSitePatterns PS01244 Aconitase family signature 2. 495 508 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 GBCGDNIH2_RS02090 6fc5a3e25ca9fedf972084cb38d53706 897 Pfam PF00694 Aconitase C-terminal domain 695 822 6.4E-46 T 29-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 GBCGDNIH2_RS02090 6fc5a3e25ca9fedf972084cb38d53706 897 Gene3D G3DSA:3.40.1060.10 242 374 1.7E-46 T 29-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 GBCGDNIH2_RS02090 6fc5a3e25ca9fedf972084cb38d53706 897 Pfam PF00330 Aconitase family (aconitate hydratase) 72 564 7.3E-184 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 GBCGDNIH2_RS06565 288563b6cf25f9dd14033162327efa8d 918 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 24 489 6.2E-150 T 29-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GBCGDNIH2_RS06565 288563b6cf25f9dd14033162327efa8d 918 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 2 885 0.0 T 29-03-2018 GBCGDNIH2_RS06565 288563b6cf25f9dd14033162327efa8d 918 SMART SM00434 3 482 1.0E-270 T 29-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GBCGDNIH2_RS06565 288563b6cf25f9dd14033162327efa8d 918 SUPERFAMILY SSF101904 788 898 1.18E-89 T 29-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal GBCGDNIH2_RS06565 288563b6cf25f9dd14033162327efa8d 918 SUPERFAMILY SSF101904 516 729 1.18E-89 T 29-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal GBCGDNIH2_RS06565 288563b6cf25f9dd14033162327efa8d 918 Gene3D G3DSA:3.90.199.10 26 206 1.4E-81 T 29-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 GBCGDNIH2_RS06565 288563b6cf25f9dd14033162327efa8d 918 Gene3D G3DSA:1.10.268.10 336 504 1.2E-43 T 29-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GBCGDNIH2_RS06565 288563b6cf25f9dd14033162327efa8d 918 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 842 888 3.8E-12 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 GBCGDNIH2_RS06565 288563b6cf25f9dd14033162327efa8d 918 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 631 674 2.9E-7 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 GBCGDNIH2_RS06565 288563b6cf25f9dd14033162327efa8d 918 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 678 727 1.8E-8 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 GBCGDNIH2_RS06565 288563b6cf25f9dd14033162327efa8d 918 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 522 561 1.6E-8 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 GBCGDNIH2_RS06565 288563b6cf25f9dd14033162327efa8d 918 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 572 619 2.9E-5 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 GBCGDNIH2_RS06565 288563b6cf25f9dd14033162327efa8d 918 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 791 834 3.9E-8 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 GBCGDNIH2_RS06565 288563b6cf25f9dd14033162327efa8d 918 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 1 890 23.483 T 29-03-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 GBCGDNIH2_RS06565 288563b6cf25f9dd14033162327efa8d 918 Gene3D G3DSA:3.30.1360.40 228 324 1.3E-36 T 29-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 GBCGDNIH2_RS06565 288563b6cf25f9dd14033162327efa8d 918 Gene3D G3DSA:2.120.10.90 516 905 9.8E-104 T 29-03-2018 GBCGDNIH2_RS06565 288563b6cf25f9dd14033162327efa8d 918 SUPERFAMILY SSF56719 22 504 3.79E-174 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 GBCGDNIH2_RS11065 b5a1981260a5cb5f8d2cfc9f4bc96dfa 487 SUPERFAMILY SSF103473 32 221 6.15E-54 T 29-03-2018 IPR020846 Major facilitator superfamily domain GBCGDNIH2_RS11065 b5a1981260a5cb5f8d2cfc9f4bc96dfa 487 SUPERFAMILY SSF103473 267 475 6.15E-54 T 29-03-2018 IPR020846 Major facilitator superfamily domain GBCGDNIH2_RS11065 b5a1981260a5cb5f8d2cfc9f4bc96dfa 487 Pfam PF07690 Major Facilitator Superfamily 36 427 3.3E-46 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 GBCGDNIH2_RS11065 b5a1981260a5cb5f8d2cfc9f4bc96dfa 487 Gene3D G3DSA:1.20.1250.20 278 482 5.1E-15 T 29-03-2018 GBCGDNIH2_RS11065 b5a1981260a5cb5f8d2cfc9f4bc96dfa 487 Gene3D G3DSA:1.20.1250.20 22 215 5.7E-31 T 29-03-2018 GBCGDNIH2_RS03490 4c56e6e724c8bc02d3f2b03a0c9c2490 677 SMART SM00433 58 670 8.3E-265 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GBCGDNIH2_RS03490 4c56e6e724c8bc02d3f2b03a0c9c2490 677 Pfam PF01751 Toprim domain 459 566 2.5E-17 T 29-03-2018 IPR006171 TOPRIM domain GBCGDNIH2_RS03490 4c56e6e724c8bc02d3f2b03a0c9c2490 677 PRINTS PR00418 DNA topoisomerase II family signature 311 324 2.3E-62 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GBCGDNIH2_RS03490 4c56e6e724c8bc02d3f2b03a0c9c2490 677 PRINTS PR00418 DNA topoisomerase II family signature 93 106 2.3E-62 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GBCGDNIH2_RS03490 4c56e6e724c8bc02d3f2b03a0c9c2490 677 PRINTS PR00418 DNA topoisomerase II family signature 460 474 2.3E-62 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GBCGDNIH2_RS03490 4c56e6e724c8bc02d3f2b03a0c9c2490 677 PRINTS PR00418 DNA topoisomerase II family signature 544 561 2.3E-62 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GBCGDNIH2_RS03490 4c56e6e724c8bc02d3f2b03a0c9c2490 677 PRINTS PR00418 DNA topoisomerase II family signature 607 623 2.3E-62 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GBCGDNIH2_RS03490 4c56e6e724c8bc02d3f2b03a0c9c2490 677 PRINTS PR00418 DNA topoisomerase II family signature 137 151 2.3E-62 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GBCGDNIH2_RS03490 4c56e6e724c8bc02d3f2b03a0c9c2490 677 PRINTS PR00418 DNA topoisomerase II family signature 526 542 2.3E-62 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GBCGDNIH2_RS03490 4c56e6e724c8bc02d3f2b03a0c9c2490 677 PRINTS PR00418 DNA topoisomerase II family signature 564 576 2.3E-62 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GBCGDNIH2_RS03490 4c56e6e724c8bc02d3f2b03a0c9c2490 677 PRINTS PR00418 DNA topoisomerase II family signature 58 73 2.3E-62 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GBCGDNIH2_RS03490 4c56e6e724c8bc02d3f2b03a0c9c2490 677 PRINTS PR01159 DNA gyrase subunit B signature 646 662 3.5E-9 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 GBCGDNIH2_RS03490 4c56e6e724c8bc02d3f2b03a0c9c2490 677 PRINTS PR01159 DNA gyrase subunit B signature 29 39 3.5E-9 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 GBCGDNIH2_RS03490 4c56e6e724c8bc02d3f2b03a0c9c2490 677 PRINTS PR01159 DNA gyrase subunit B signature 510 519 3.5E-9 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 GBCGDNIH2_RS03490 4c56e6e724c8bc02d3f2b03a0c9c2490 677 PRINTS PR01159 DNA gyrase subunit B signature 415 435 3.5E-9 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 GBCGDNIH2_RS03490 4c56e6e724c8bc02d3f2b03a0c9c2490 677 PRINTS PR01159 DNA gyrase subunit B signature 353 369 3.5E-9 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 GBCGDNIH2_RS03490 4c56e6e724c8bc02d3f2b03a0c9c2490 677 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 603 666 6.2E-21 T 29-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 GBCGDNIH2_RS03490 4c56e6e724c8bc02d3f2b03a0c9c2490 677 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 54 199 4.5E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS03490 4c56e6e724c8bc02d3f2b03a0c9c2490 677 Pfam PF00204 DNA gyrase B 284 431 1.4E-40 T 29-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GBCGDNIH2_RS03490 4c56e6e724c8bc02d3f2b03a0c9c2490 677 SUPERFAMILY SSF54211 290 431 7.02E-38 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold GBCGDNIH2_RS03490 4c56e6e724c8bc02d3f2b03a0c9c2490 677 Gene3D G3DSA:3.30.565.10 41 239 5.9E-58 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS03490 4c56e6e724c8bc02d3f2b03a0c9c2490 677 Gene3D G3DSA:3.40.50.670 439 673 1.1E-84 T 29-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GBCGDNIH2_RS03490 4c56e6e724c8bc02d3f2b03a0c9c2490 677 Gene3D G3DSA:3.30.230.10 255 433 1.8E-36 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup GBCGDNIH2_RS03490 4c56e6e724c8bc02d3f2b03a0c9c2490 677 SUPERFAMILY SSF56719 434 670 2.62E-76 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 GBCGDNIH2_RS03490 4c56e6e724c8bc02d3f2b03a0c9c2490 677 ProSitePatterns PS00177 DNA topoisomerase II signature. 462 470 - T 29-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GBCGDNIH2_RS03490 4c56e6e724c8bc02d3f2b03a0c9c2490 677 SUPERFAMILY SSF55874 29 232 6.81E-58 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS03490 4c56e6e724c8bc02d3f2b03a0c9c2490 677 Hamap MF_00938 DNA topoisomerase 4 subunit B [parE]. 26 674 41.875 T 29-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 GBCGDNIH2_RS03490 4c56e6e724c8bc02d3f2b03a0c9c2490 677 TIGRFAM TIGR01055 parE_Gneg: DNA topoisomerase IV, B subunit 28 668 5.7E-227 T 29-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 GBCGDNIH2_RS03490 4c56e6e724c8bc02d3f2b03a0c9c2490 677 SMART SM00387 54 200 6.9E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS05595 d95f21aaf029bc0922c8442532508ba9 159 ProSitePatterns PS00763 Glutathione peroxidases signature 2. 60 67 - T 29-03-2018 IPR029760 Glutathione peroxidase conserved site Reactome: R-HSA-3299685 GBCGDNIH2_RS05595 d95f21aaf029bc0922c8442532508ba9 159 SUPERFAMILY SSF52833 3 159 1.14E-59 T 29-03-2018 IPR012336 Thioredoxin-like fold GBCGDNIH2_RS05595 d95f21aaf029bc0922c8442532508ba9 159 PIRSF PIRSF000303 1 159 9.3E-65 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 GBCGDNIH2_RS05595 d95f21aaf029bc0922c8442532508ba9 159 PRINTS PR01011 Glutathione peroxidase family signature 123 132 2.3E-19 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 GBCGDNIH2_RS05595 d95f21aaf029bc0922c8442532508ba9 159 PRINTS PR01011 Glutathione peroxidase family signature 22 39 2.3E-19 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 GBCGDNIH2_RS05595 d95f21aaf029bc0922c8442532508ba9 159 PRINTS PR01011 Glutathione peroxidase family signature 57 73 2.3E-19 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 GBCGDNIH2_RS05595 d95f21aaf029bc0922c8442532508ba9 159 Pfam PF00255 Glutathione peroxidase 4 110 6.1E-42 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 GBCGDNIH2_RS05595 d95f21aaf029bc0922c8442532508ba9 159 Gene3D G3DSA:3.40.30.10 2 159 4.3E-44 T 29-03-2018 GBCGDNIH2_RS02665 1ef135391217ab9a67e264a52de55580 295 SMART SM00460 175 246 1.3E-14 T 29-03-2018 IPR002931 Transglutaminase-like GBCGDNIH2_RS02665 1ef135391217ab9a67e264a52de55580 295 Gene3D G3DSA:3.90.260.10 164 252 1.9E-8 T 29-03-2018 IPR002931 Transglutaminase-like GBCGDNIH2_RS02665 1ef135391217ab9a67e264a52de55580 295 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 4 82 5.6E-24 T 29-03-2018 IPR013589 Bacterial transglutaminase-like, N-terminal GBCGDNIH2_RS02665 1ef135391217ab9a67e264a52de55580 295 Pfam PF01841 Transglutaminase-like superfamily 145 244 8.3E-18 T 29-03-2018 IPR002931 Transglutaminase-like GBCGDNIH2_RS02665 1ef135391217ab9a67e264a52de55580 295 SUPERFAMILY SSF54001 86 271 2.52E-37 T 29-03-2018 GBCGDNIH2_RS11980 d3ec27cfe00503853eb483af83ce430d 310 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 1 117 2.2E-48 T 29-03-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 GBCGDNIH2_RS11980 d3ec27cfe00503853eb483af83ce430d 310 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 1 310 1.7E-114 T 29-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 GBCGDNIH2_RS11980 d3ec27cfe00503853eb483af83ce430d 310 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 125 140 - T 29-03-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 GBCGDNIH2_RS11980 d3ec27cfe00503853eb483af83ce430d 310 Gene3D G3DSA:3.40.50.2020 1 141 9.4E-66 T 29-03-2018 GBCGDNIH2_RS11980 d3ec27cfe00503853eb483af83ce430d 310 SMART SM01400 1 117 1.5E-77 T 29-03-2018 GBCGDNIH2_RS11980 d3ec27cfe00503853eb483af83ce430d 310 Pfam PF14572 Phosphoribosyl synthetase-associated domain 201 309 3.4E-20 T 29-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 GBCGDNIH2_RS11980 d3ec27cfe00503853eb483af83ce430d 310 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 1 310 47.567 T 29-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 GBCGDNIH2_RS11980 d3ec27cfe00503853eb483af83ce430d 310 SUPERFAMILY SSF53271 66 300 3.69E-60 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like GBCGDNIH2_RS11980 d3ec27cfe00503853eb483af83ce430d 310 Gene3D G3DSA:3.40.50.2020 142 310 1.0E-38 T 29-03-2018 GBCGDNIH2_RS06200 06494c065c9e277e52785c4bcef44980 203 Pfam PF08445 FR47-like protein 105 162 9.7E-10 T 29-03-2018 IPR013653 FR47-like GO:0016747 GBCGDNIH2_RS06200 06494c065c9e277e52785c4bcef44980 203 SUPERFAMILY SSF55729 1 166 9.0E-21 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase GBCGDNIH2_RS06200 06494c065c9e277e52785c4bcef44980 203 Gene3D G3DSA:3.40.630.30 2 185 1.7E-23 T 29-03-2018 GBCGDNIH2_RS07935 b674a070ec794a9a736581847d00187e 723 Gene3D G3DSA:2.170.130.10 39 191 4.0E-20 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 GBCGDNIH2_RS07935 b674a070ec794a9a736581847d00187e 723 Pfam PF00593 TonB dependent receptor 257 722 1.9E-56 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 GBCGDNIH2_RS07935 b674a070ec794a9a736581847d00187e 723 Gene3D G3DSA:2.40.170.20 197 723 6.9E-81 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 GBCGDNIH2_RS07935 b674a070ec794a9a736581847d00187e 723 SUPERFAMILY SSF56935 45 723 4.35E-120 T 29-03-2018 GBCGDNIH2_RS07935 b674a070ec794a9a736581847d00187e 723 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 86 723 1.1E-98 T 29-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 GBCGDNIH2_RS07935 b674a070ec794a9a736581847d00187e 723 Pfam PF07715 TonB-dependent Receptor Plug Domain 84 184 6.0E-13 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 GBCGDNIH2_RS06650 f990b5605acc8257e1ee4ba815054bf9 757 Gene3D G3DSA:2.30.30.60 597 641 1.6E-6 T 29-03-2018 GBCGDNIH2_RS06650 f990b5605acc8257e1ee4ba815054bf9 757 Gene3D G3DSA:3.30.70.100 642 741 8.0E-7 T 29-03-2018 GBCGDNIH2_RS06650 f990b5605acc8257e1ee4ba815054bf9 757 SUPERFAMILY SSF82689 652 745 2.62E-8 T 29-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 GBCGDNIH2_RS06650 f990b5605acc8257e1ee4ba815054bf9 757 SUPERFAMILY SSF50182 580 641 1.05E-10 T 29-03-2018 IPR010920 LSM domain GBCGDNIH2_RS06650 f990b5605acc8257e1ee4ba815054bf9 757 SUPERFAMILY SSF82861 503 578 3.92E-14 T 29-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 GBCGDNIH2_RS06650 f990b5605acc8257e1ee4ba815054bf9 757 Pfam PF00924 Mechanosensitive ion channel 537 736 2.4E-35 T 29-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 GBCGDNIH2_RS05065 aa576d385e8e170821da5b7cfff30a6d 225 SUPERFAMILY SSF56281 12 225 2.94E-48 T 29-03-2018 IPR001279 Metallo-beta-lactamase GBCGDNIH2_RS05065 aa576d385e8e170821da5b7cfff30a6d 225 Gene3D G3DSA:3.60.15.10 12 225 9.2E-35 T 29-03-2018 IPR001279 Metallo-beta-lactamase GBCGDNIH2_RS05065 aa576d385e8e170821da5b7cfff30a6d 225 Pfam PF00753 Metallo-beta-lactamase superfamily 20 208 1.9E-22 T 29-03-2018 IPR001279 Metallo-beta-lactamase GBCGDNIH2_RS05065 aa576d385e8e170821da5b7cfff30a6d 225 SMART SM00849 23 208 2.1E-31 T 29-03-2018 IPR001279 Metallo-beta-lactamase GBCGDNIH2_RS08105 34d0763a54e92585199ae38f73c93cf4 442 Gene3D G3DSA:2.40.50.100 277 424 0.001 T 29-03-2018 GBCGDNIH2_RS08105 34d0763a54e92585199ae38f73c93cf4 442 Gene3D G3DSA:2.40.50.100 86 276 5.9E-6 T 29-03-2018 GBCGDNIH2_RS08105 34d0763a54e92585199ae38f73c93cf4 442 Pfam PF13437 HlyD family secretion protein 263 346 5.7E-9 T 29-03-2018 GBCGDNIH2_RS08105 34d0763a54e92585199ae38f73c93cf4 442 TIGRFAM TIGR03794 NHLM_micro_HlyD: NHLM bacteriocin system secretion protein 29 438 8.3E-60 T 29-03-2018 IPR022275 NHPM bacteriocin system secretion protein, HylD GBCGDNIH2_RS10295 bc81ef3111bda39d167874d15104b0c8 506 Pfam PF00199 Catalase 20 401 4.2E-190 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 GBCGDNIH2_RS10295 bc81ef3111bda39d167874d15104b0c8 506 Gene3D G3DSA:2.40.180.10 10 370 2.3E-163 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 GBCGDNIH2_RS10295 bc81ef3111bda39d167874d15104b0c8 506 SUPERFAMILY SSF56634 14 494 1.57E-210 T 29-03-2018 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 GBCGDNIH2_RS10295 bc81ef3111bda39d167874d15104b0c8 506 SMART SM01060 20 404 1.4E-288 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 GBCGDNIH2_RS10295 bc81ef3111bda39d167874d15104b0c8 506 PIRSF PIRSF038928 10 494 3.7E-226 T 29-03-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 GBCGDNIH2_RS10295 bc81ef3111bda39d167874d15104b0c8 506 PRINTS PR00067 Catalase signature 136 154 2.8E-71 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 GBCGDNIH2_RS10295 bc81ef3111bda39d167874d15104b0c8 506 PRINTS PR00067 Catalase signature 333 359 2.8E-71 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 GBCGDNIH2_RS10295 bc81ef3111bda39d167874d15104b0c8 506 PRINTS PR00067 Catalase signature 33 56 2.8E-71 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 GBCGDNIH2_RS10295 bc81ef3111bda39d167874d15104b0c8 506 PRINTS PR00067 Catalase signature 96 114 2.8E-71 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 GBCGDNIH2_RS10295 bc81ef3111bda39d167874d15104b0c8 506 PRINTS PR00067 Catalase signature 117 134 2.8E-71 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 GBCGDNIH2_RS10295 bc81ef3111bda39d167874d15104b0c8 506 PRINTS PR00067 Catalase signature 301 328 2.8E-71 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 GBCGDNIH2_RS10295 bc81ef3111bda39d167874d15104b0c8 506 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 346 354 - T 29-03-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 GBCGDNIH2_RS10295 bc81ef3111bda39d167874d15104b0c8 506 Pfam PF06628 Catalase-related immune-responsive 427 488 3.9E-20 T 29-03-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 GBCGDNIH2_RS03800 a21499a3bbb4521fbac064458fbcd480 239 SUPERFAMILY SSF52172 6 129 3.56E-39 T 29-03-2018 IPR011006 CheY-like superfamily GBCGDNIH2_RS03800 a21499a3bbb4521fbac064458fbcd480 239 SMART SM00448 5 115 1.9E-42 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GBCGDNIH2_RS03800 a21499a3bbb4521fbac064458fbcd480 239 SUPERFAMILY SSF46894 139 233 3.97E-24 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 GBCGDNIH2_RS03800 a21499a3bbb4521fbac064458fbcd480 239 SMART SM00862 156 232 5.5E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 GBCGDNIH2_RS03800 a21499a3bbb4521fbac064458fbcd480 239 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 232 1.8E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 GBCGDNIH2_RS03800 a21499a3bbb4521fbac064458fbcd480 239 Pfam PF00072 Response regulator receiver domain 7 116 1.4E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GBCGDNIH2_RS03800 a21499a3bbb4521fbac064458fbcd480 239 Gene3D G3DSA:1.10.10.10 130 238 8.9E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS03800 a21499a3bbb4521fbac064458fbcd480 239 Gene3D G3DSA:3.40.50.2300 4 129 7.5E-37 T 29-03-2018 GBCGDNIH2_RS02515 9c484e853c1fc4e30e3b8f61dc2fedbd 350 SUPERFAMILY SSF55961 123 330 4.39E-25 T 29-03-2018 GBCGDNIH2_RS02515 9c484e853c1fc4e30e3b8f61dc2fedbd 350 Pfam PF00355 Rieske [2Fe-2S] domain 25 105 1.4E-19 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 GBCGDNIH2_RS02515 9c484e853c1fc4e30e3b8f61dc2fedbd 350 Gene3D G3DSA:3.90.380.10 127 332 6.0E-29 T 29-03-2018 GBCGDNIH2_RS02515 9c484e853c1fc4e30e3b8f61dc2fedbd 350 SUPERFAMILY SSF50022 9 134 1.44E-37 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 GBCGDNIH2_RS02515 9c484e853c1fc4e30e3b8f61dc2fedbd 350 Gene3D G3DSA:2.102.10.10 11 126 2.3E-29 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 GBCGDNIH2_RS07230 e84c8fa1e83eb254c180dead7698e7f9 336 SMART SM00829 19 332 2.8E-55 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 GBCGDNIH2_RS07230 e84c8fa1e83eb254c180dead7698e7f9 336 Gene3D G3DSA:3.40.50.720 144 318 9.3E-44 T 29-03-2018 GBCGDNIH2_RS07230 e84c8fa1e83eb254c180dead7698e7f9 336 Gene3D G3DSA:3.90.180.10 1 143 4.6E-39 T 29-03-2018 GBCGDNIH2_RS07230 e84c8fa1e83eb254c180dead7698e7f9 336 Pfam PF00107 Zinc-binding dehydrogenase 160 284 3.2E-28 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 GBCGDNIH2_RS07230 e84c8fa1e83eb254c180dead7698e7f9 336 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 37 108 2.0E-8 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 GBCGDNIH2_RS07230 e84c8fa1e83eb254c180dead7698e7f9 336 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 10 333 1.3E-141 T 29-03-2018 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 GBCGDNIH2_RS07230 e84c8fa1e83eb254c180dead7698e7f9 336 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 149 170 - T 29-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 GBCGDNIH2_RS07230 e84c8fa1e83eb254c180dead7698e7f9 336 SUPERFAMILY SSF50129 10 150 3.3E-36 T 29-03-2018 IPR011032 GroES-like GBCGDNIH2_RS07230 e84c8fa1e83eb254c180dead7698e7f9 336 SUPERFAMILY SSF51735 120 296 2.39E-50 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS06435 d3177fea321cffd4fd7988910524d11e 700 Pfam PF01464 Transglycosylase SLT domain 548 644 3.6E-24 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 GBCGDNIH2_RS06435 d3177fea321cffd4fd7988910524d11e 700 Gene3D G3DSA:1.25.20.10 66 435 1.2E-21 T 29-03-2018 GBCGDNIH2_RS06435 d3177fea321cffd4fd7988910524d11e 700 Gene3D G3DSA:1.10.530.10 544 690 5.7E-36 T 29-03-2018 GBCGDNIH2_RS06435 d3177fea321cffd4fd7988910524d11e 700 SUPERFAMILY SSF48435 73 527 1.11E-52 T 29-03-2018 IPR016026 Lytic transglycosylase, superhelical U-shaped and linker domain GO:0004553|GO:0042597 GBCGDNIH2_RS06435 d3177fea321cffd4fd7988910524d11e 700 SUPERFAMILY SSF53955 548 684 4.3E-42 T 29-03-2018 IPR023346 Lysozyme-like domain GBCGDNIH2_RS06435 d3177fea321cffd4fd7988910524d11e 700 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 556 584 - T 29-03-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 GBCGDNIH2_RS04010 9c7df42e3d6701dfbaaf0b422cdcab1e 533 Gene3D G3DSA:2.30.40.10 426 494 0.0099 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 GBCGDNIH2_RS04010 9c7df42e3d6701dfbaaf0b422cdcab1e 533 Gene3D G3DSA:2.30.40.10 1 63 3.9E-15 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 GBCGDNIH2_RS04010 9c7df42e3d6701dfbaaf0b422cdcab1e 533 TIGRFAM TIGR03121 one_C_dehyd_A: formylmethanofuran dehydrogenase subunit A 3 521 4.6E-184 T 29-03-2018 IPR012027 Formylmethanofuran dehydrogenase, subunit A GBCGDNIH2_RS04010 9c7df42e3d6701dfbaaf0b422cdcab1e 533 Pfam PF07969 Amidohydrolase family 41 478 7.3E-45 T 29-03-2018 IPR013108 Amidohydrolase 3 GBCGDNIH2_RS04010 9c7df42e3d6701dfbaaf0b422cdcab1e 533 SUPERFAMILY SSF51556 53 437 3.18E-23 T 29-03-2018 IPR032466 Metal-dependent hydrolase GBCGDNIH2_RS04010 9c7df42e3d6701dfbaaf0b422cdcab1e 533 SUPERFAMILY SSF51338 3 66 5.59E-14 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 GBCGDNIH2_RS04010 9c7df42e3d6701dfbaaf0b422cdcab1e 533 Gene3D G3DSA:3.20.20.140 64 425 1.1E-13 T 29-03-2018 GBCGDNIH2_RS04010 9c7df42e3d6701dfbaaf0b422cdcab1e 533 PIRSF PIRSF006453 1 532 1.9E-216 T 29-03-2018 IPR012027 Formylmethanofuran dehydrogenase, subunit A GBCGDNIH2_RS04010 9c7df42e3d6701dfbaaf0b422cdcab1e 533 SUPERFAMILY SSF51338 410 495 1.37E-16 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 GBCGDNIH2_RS08985 fdf754a2ed343e95e15104a82efbd939 512 SUPERFAMILY SSF64158 81 299 1.44E-73 T 29-03-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 GBCGDNIH2_RS08985 fdf754a2ed343e95e15104a82efbd939 512 Gene3D G3DSA:3.40.720.10 298 481 4.7E-24 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 GBCGDNIH2_RS08985 fdf754a2ed343e95e15104a82efbd939 512 Pfam PF01676 Metalloenzyme superfamily 9 500 1.6E-77 T 29-03-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 GBCGDNIH2_RS08985 fdf754a2ed343e95e15104a82efbd939 512 Hamap MF_01038 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [gpmI]. 8 512 47.303 T 29-03-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 GBCGDNIH2_RS08985 fdf754a2ed343e95e15104a82efbd939 512 Pfam PF06415 BPG-independent PGAM N-terminus (iPGM_N) 86 294 4.1E-67 T 29-03-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 GBCGDNIH2_RS08985 fdf754a2ed343e95e15104a82efbd939 512 PIRSF PIRSF001492 4 512 1.0E-191 T 29-03-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 GBCGDNIH2_RS08985 fdf754a2ed343e95e15104a82efbd939 512 Gene3D G3DSA:3.40.1450.10 81 297 1.0E-74 T 29-03-2018 GBCGDNIH2_RS08985 fdf754a2ed343e95e15104a82efbd939 512 SUPERFAMILY SSF53649 8 81 2.45E-75 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 GBCGDNIH2_RS08985 fdf754a2ed343e95e15104a82efbd939 512 SUPERFAMILY SSF53649 308 511 2.45E-75 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 GBCGDNIH2_RS08985 fdf754a2ed343e95e15104a82efbd939 512 TIGRFAM TIGR01307 pgm_bpd_ind: phosphoglycerate mutase (2,3-diphosphoglycerate-independent) 9 511 9.0E-196 T 29-03-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 GBCGDNIH2_RS05870 5b2a6fe93a77b068dc511732eb2d9db7 187 SUPERFAMILY SSF50249 130 186 1.25E-17 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold GBCGDNIH2_RS05870 5b2a6fe93a77b068dc511732eb2d9db7 187 Gene3D G3DSA:2.40.50.140 130 185 2.9E-24 T 29-03-2018 GBCGDNIH2_RS05870 5b2a6fe93a77b068dc511732eb2d9db7 187 Gene3D G3DSA:2.30.30.30 3 62 7.5E-22 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 GBCGDNIH2_RS05870 5b2a6fe93a77b068dc511732eb2d9db7 187 Pfam PF09285 Elongation factor P, C-terminal 130 185 3.2E-24 T 29-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 GBCGDNIH2_RS05870 5b2a6fe93a77b068dc511732eb2d9db7 187 SUPERFAMILY SSF50104 4 63 4.99E-16 T 29-03-2018 IPR008991 Translation protein SH3-like domain GBCGDNIH2_RS05870 5b2a6fe93a77b068dc511732eb2d9db7 187 SMART SM00841 130 185 9.6E-31 T 29-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 GBCGDNIH2_RS05870 5b2a6fe93a77b068dc511732eb2d9db7 187 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 5 61 2.5E-20 T 29-03-2018 IPR013185 Translation elongation factor, KOW-like GBCGDNIH2_RS05870 5b2a6fe93a77b068dc511732eb2d9db7 187 TIGRFAM TIGR00038 efp: translation elongation factor P 4 186 8.5E-71 T 29-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 GBCGDNIH2_RS05870 5b2a6fe93a77b068dc511732eb2d9db7 187 PIRSF PIRSF005901 1 187 2.5E-68 T 29-03-2018 IPR020599 Translation elongation factor P/YeiP GBCGDNIH2_RS05870 5b2a6fe93a77b068dc511732eb2d9db7 187 Hamap MF_00141 Elongation factor P [efp]. 2 186 42.626 T 29-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 GBCGDNIH2_RS05870 5b2a6fe93a77b068dc511732eb2d9db7 187 SMART SM01185 68 122 7.5E-24 T 29-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 GBCGDNIH2_RS05870 5b2a6fe93a77b068dc511732eb2d9db7 187 ProSitePatterns PS01275 Elongation factor P signature. 151 170 - T 29-03-2018 IPR013852 Translation elongation factor P/YeiP, conserved site GBCGDNIH2_RS05870 5b2a6fe93a77b068dc511732eb2d9db7 187 Gene3D G3DSA:2.40.50.140 66 128 1.0E-21 T 29-03-2018 GBCGDNIH2_RS05870 5b2a6fe93a77b068dc511732eb2d9db7 187 Pfam PF01132 Elongation factor P (EF-P) OB domain 69 122 1.5E-20 T 29-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 GBCGDNIH2_RS05870 5b2a6fe93a77b068dc511732eb2d9db7 187 SUPERFAMILY SSF50249 67 127 2.18E-16 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold GBCGDNIH2_RS04530 aa4a15b657a2cfb3a27819abe0df4b74 592 SMART SM00382 411 583 5.8E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS04530 aa4a15b657a2cfb3a27819abe0df4b74 592 Pfam PF06472 ABC transporter transmembrane region 2 6 303 1.6E-63 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 GBCGDNIH2_RS04530 aa4a15b657a2cfb3a27819abe0df4b74 592 SUPERFAMILY SSF52540 381 580 1.66E-36 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS04530 aa4a15b657a2cfb3a27819abe0df4b74 592 Pfam PF00005 ABC transporter 404 536 1.3E-17 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GBCGDNIH2_RS04530 aa4a15b657a2cfb3a27819abe0df4b74 592 Gene3D G3DSA:3.40.50.300 379 587 3.6E-35 T 29-03-2018 GBCGDNIH2_RS04530 aa4a15b657a2cfb3a27819abe0df4b74 592 SUPERFAMILY SSF90123 28 349 1.01E-21 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 GBCGDNIH2_RS04530 aa4a15b657a2cfb3a27819abe0df4b74 592 ProSitePatterns PS00211 ABC transporters family signature. 508 522 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GBCGDNIH2_RS04530 aa4a15b657a2cfb3a27819abe0df4b74 592 Gene3D G3DSA:1.20.1560.10 5 360 8.7E-35 T 29-03-2018 GBCGDNIH2_RS08715 46b35e2f1d50cb0ca4ba7b4fb1109fde 271 Gene3D G3DSA:1.10.150.20 90 135 7.5E-8 T 29-03-2018 GBCGDNIH2_RS08715 46b35e2f1d50cb0ca4ba7b4fb1109fde 271 SUPERFAMILY SSF47781 62 129 5.56E-9 T 29-03-2018 IPR010994 RuvA domain 2-like GBCGDNIH2_RS08715 46b35e2f1d50cb0ca4ba7b4fb1109fde 271 Pfam PF04002 RadC-like JAB domain 150 269 4.3E-45 T 29-03-2018 IPR025657 RadC-like JAB domain GBCGDNIH2_RS08715 46b35e2f1d50cb0ca4ba7b4fb1109fde 271 TIGRFAM TIGR00608 radc: DNA repair protein RadC 58 271 2.6E-71 T 29-03-2018 IPR001405 RadC protein GBCGDNIH2_RS08715 46b35e2f1d50cb0ca4ba7b4fb1109fde 271 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 220 225 - T 29-03-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site GBCGDNIH2_RS08715 46b35e2f1d50cb0ca4ba7b4fb1109fde 271 SUPERFAMILY SSF102712 196 239 2.75E-6 T 29-03-2018 GBCGDNIH2_RS08715 46b35e2f1d50cb0ca4ba7b4fb1109fde 271 Gene3D G3DSA:3.40.140.10 146 271 5.9E-52 T 29-03-2018 GBCGDNIH2_RS01660 ad5580c82cbf67cbcc86eaa39f2a53a4 810 PRINTS PR01159 DNA gyrase subunit B signature 763 775 2.0E-71 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 GBCGDNIH2_RS01660 ad5580c82cbf67cbcc86eaa39f2a53a4 810 PRINTS PR01159 DNA gyrase subunit B signature 779 795 2.0E-71 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 GBCGDNIH2_RS01660 ad5580c82cbf67cbcc86eaa39f2a53a4 810 PRINTS PR01159 DNA gyrase subunit B signature 325 341 2.0E-71 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 GBCGDNIH2_RS01660 ad5580c82cbf67cbcc86eaa39f2a53a4 810 PRINTS PR01159 DNA gyrase subunit B signature 373 387 2.0E-71 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 GBCGDNIH2_RS01660 ad5580c82cbf67cbcc86eaa39f2a53a4 810 PRINTS PR01159 DNA gyrase subunit B signature 14 24 2.0E-71 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 GBCGDNIH2_RS01660 ad5580c82cbf67cbcc86eaa39f2a53a4 810 PRINTS PR01159 DNA gyrase subunit B signature 231 253 2.0E-71 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 GBCGDNIH2_RS01660 ad5580c82cbf67cbcc86eaa39f2a53a4 810 PRINTS PR01159 DNA gyrase subunit B signature 190 205 2.0E-71 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 GBCGDNIH2_RS01660 ad5580c82cbf67cbcc86eaa39f2a53a4 810 PRINTS PR01159 DNA gyrase subunit B signature 257 275 2.0E-71 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 GBCGDNIH2_RS01660 ad5580c82cbf67cbcc86eaa39f2a53a4 810 PRINTS PR01159 DNA gyrase subunit B signature 483 492 2.0E-71 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 GBCGDNIH2_RS01660 ad5580c82cbf67cbcc86eaa39f2a53a4 810 PRINTS PR01159 DNA gyrase subunit B signature 205 218 2.0E-71 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 GBCGDNIH2_RS01660 ad5580c82cbf67cbcc86eaa39f2a53a4 810 PRINTS PR01159 DNA gyrase subunit B signature 387 407 2.0E-71 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 GBCGDNIH2_RS01660 ad5580c82cbf67cbcc86eaa39f2a53a4 810 SUPERFAMILY SSF56719 736 801 2.48E-81 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 GBCGDNIH2_RS01660 ad5580c82cbf67cbcc86eaa39f2a53a4 810 SUPERFAMILY SSF56719 407 578 2.48E-81 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 GBCGDNIH2_RS01660 ad5580c82cbf67cbcc86eaa39f2a53a4 810 SUPERFAMILY SSF55874 14 219 4.85E-66 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS01660 ad5580c82cbf67cbcc86eaa39f2a53a4 810 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 11 810 93.285 T 29-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 GBCGDNIH2_RS01660 ad5580c82cbf67cbcc86eaa39f2a53a4 810 Pfam PF00204 DNA gyrase B 232 403 5.3E-52 T 29-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GBCGDNIH2_RS01660 ad5580c82cbf67cbcc86eaa39f2a53a4 810 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 738 798 3.5E-26 T 29-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 GBCGDNIH2_RS01660 ad5580c82cbf67cbcc86eaa39f2a53a4 810 Pfam PF01751 Toprim domain 432 549 6.5E-17 T 29-03-2018 IPR006171 TOPRIM domain GBCGDNIH2_RS01660 ad5580c82cbf67cbcc86eaa39f2a53a4 810 ProSitePatterns PS00177 DNA topoisomerase II signature. 435 443 - T 29-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GBCGDNIH2_RS01660 ad5580c82cbf67cbcc86eaa39f2a53a4 810 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 41 181 4.8E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS01660 ad5580c82cbf67cbcc86eaa39f2a53a4 810 SMART SM00433 44 803 8.1E-235 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GBCGDNIH2_RS01660 ad5580c82cbf67cbcc86eaa39f2a53a4 810 Gene3D G3DSA:3.30.565.10 26 231 1.6E-70 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS01660 ad5580c82cbf67cbcc86eaa39f2a53a4 810 SUPERFAMILY SSF54211 232 404 7.4E-49 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold GBCGDNIH2_RS01660 ad5580c82cbf67cbcc86eaa39f2a53a4 810 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 14 810 3.4E-278 T 29-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 GBCGDNIH2_RS01660 ad5580c82cbf67cbcc86eaa39f2a53a4 810 SMART SM00387 40 185 9.7E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS01660 ad5580c82cbf67cbcc86eaa39f2a53a4 810 Gene3D G3DSA:3.40.50.670 412 807 2.5E-101 T 29-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GBCGDNIH2_RS01660 ad5580c82cbf67cbcc86eaa39f2a53a4 810 Gene3D G3DSA:3.30.230.10 232 405 6.7E-53 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup GBCGDNIH2_RS01660 ad5580c82cbf67cbcc86eaa39f2a53a4 810 PRINTS PR00418 DNA topoisomerase II family signature 433 447 2.2E-66 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GBCGDNIH2_RS01660 ad5580c82cbf67cbcc86eaa39f2a53a4 810 PRINTS PR00418 DNA topoisomerase II family signature 523 540 2.2E-66 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GBCGDNIH2_RS01660 ad5580c82cbf67cbcc86eaa39f2a53a4 810 PRINTS PR00418 DNA topoisomerase II family signature 505 521 2.2E-66 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GBCGDNIH2_RS01660 ad5580c82cbf67cbcc86eaa39f2a53a4 810 PRINTS PR00418 DNA topoisomerase II family signature 543 555 2.2E-66 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GBCGDNIH2_RS01660 ad5580c82cbf67cbcc86eaa39f2a53a4 810 PRINTS PR00418 DNA topoisomerase II family signature 79 92 2.2E-66 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GBCGDNIH2_RS01660 ad5580c82cbf67cbcc86eaa39f2a53a4 810 PRINTS PR00418 DNA topoisomerase II family signature 122 136 2.2E-66 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GBCGDNIH2_RS01660 ad5580c82cbf67cbcc86eaa39f2a53a4 810 PRINTS PR00418 DNA topoisomerase II family signature 283 296 2.2E-66 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GBCGDNIH2_RS01660 ad5580c82cbf67cbcc86eaa39f2a53a4 810 PRINTS PR00418 DNA topoisomerase II family signature 44 59 2.2E-66 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GBCGDNIH2_RS01660 ad5580c82cbf67cbcc86eaa39f2a53a4 810 PRINTS PR00418 DNA topoisomerase II family signature 742 758 2.2E-66 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GBCGDNIH2_RS02565 0d4195b07fa1dd77a84572aaeb11cc8f 424 Gene3D G3DSA:3.90.1150.10 315 418 4.2E-6 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 GBCGDNIH2_RS02565 0d4195b07fa1dd77a84572aaeb11cc8f 424 Gene3D G3DSA:3.40.640.10 189 314 6.0E-38 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GBCGDNIH2_RS02565 0d4195b07fa1dd77a84572aaeb11cc8f 424 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 235 272 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 GBCGDNIH2_RS02565 0d4195b07fa1dd77a84572aaeb11cc8f 424 SUPERFAMILY SSF53383 7 418 9.25E-115 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase GBCGDNIH2_RS02565 0d4195b07fa1dd77a84572aaeb11cc8f 424 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 12 415 1.2E-156 T 29-03-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 GBCGDNIH2_RS02565 0d4195b07fa1dd77a84572aaeb11cc8f 424 Gene3D G3DSA:3.90.1150.10 2 188 3.8E-46 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 GBCGDNIH2_RS02565 0d4195b07fa1dd77a84572aaeb11cc8f 424 Pfam PF00202 Aminotransferase class-III 26 410 2.4E-107 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 GBCGDNIH2_RS06120 4359a8264e29cecfbbe12c4c8ab39914 1148 Gene3D G3DSA:3.30.450.20 832 972 5.9E-16 T 29-03-2018 GBCGDNIH2_RS06120 4359a8264e29cecfbbe12c4c8ab39914 1148 SMART SM00091 835 902 5.0 T 29-03-2018 IPR000014 PAS domain GBCGDNIH2_RS06120 4359a8264e29cecfbbe12c4c8ab39914 1148 SMART SM00091 518 584 16.0 T 29-03-2018 IPR000014 PAS domain GBCGDNIH2_RS06120 4359a8264e29cecfbbe12c4c8ab39914 1148 SMART SM00091 713 781 22.0 T 29-03-2018 IPR000014 PAS domain GBCGDNIH2_RS06120 4359a8264e29cecfbbe12c4c8ab39914 1148 Pfam PF03705 CheR methyltransferase, all-alpha domain 222 270 3.6E-13 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal GBCGDNIH2_RS06120 4359a8264e29cecfbbe12c4c8ab39914 1148 SMART SM00911 961 1042 1.8E-26 T 29-03-2018 IPR011102 Signal transduction histidine kinase, HWE region GO:0004673 GBCGDNIH2_RS06120 4359a8264e29cecfbbe12c4c8ab39914 1148 Gene3D G3DSA:1.10.155.10 213 281 2.9E-13 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal GBCGDNIH2_RS06120 4359a8264e29cecfbbe12c4c8ab39914 1148 Pfam PF01739 CheR methyltransferase, SAM binding domain 284 474 2.3E-50 T 29-03-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal GBCGDNIH2_RS06120 4359a8264e29cecfbbe12c4c8ab39914 1148 SMART SM00138 218 479 3.8E-79 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 GBCGDNIH2_RS06120 4359a8264e29cecfbbe12c4c8ab39914 1148 Pfam PF08447 PAS fold 876 941 1.0E-9 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 GBCGDNIH2_RS06120 4359a8264e29cecfbbe12c4c8ab39914 1148 SUPERFAMILY SSF52738 20 204 4.58E-52 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 GBCGDNIH2_RS06120 4359a8264e29cecfbbe12c4c8ab39914 1148 Pfam PF07536 HWE histidine kinase 961 1041 1.6E-17 T 29-03-2018 IPR011102 Signal transduction histidine kinase, HWE region GO:0004673 GBCGDNIH2_RS06120 4359a8264e29cecfbbe12c4c8ab39914 1148 PRINTS PR00996 Glutamate methyltransferase family signature 317 337 1.7E-26 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 GBCGDNIH2_RS06120 4359a8264e29cecfbbe12c4c8ab39914 1148 PRINTS PR00996 Glutamate methyltransferase family signature 277 289 1.7E-26 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 GBCGDNIH2_RS06120 4359a8264e29cecfbbe12c4c8ab39914 1148 PRINTS PR00996 Glutamate methyltransferase family signature 353 369 1.7E-26 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 GBCGDNIH2_RS06120 4359a8264e29cecfbbe12c4c8ab39914 1148 PRINTS PR00996 Glutamate methyltransferase family signature 438 461 1.7E-26 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 GBCGDNIH2_RS06120 4359a8264e29cecfbbe12c4c8ab39914 1148 PRINTS PR00996 Glutamate methyltransferase family signature 240 253 1.7E-26 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 GBCGDNIH2_RS06120 4359a8264e29cecfbbe12c4c8ab39914 1148 PRINTS PR00996 Glutamate methyltransferase family signature 419 433 1.7E-26 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 GBCGDNIH2_RS06120 4359a8264e29cecfbbe12c4c8ab39914 1148 Gene3D G3DSA:3.30.450.20 709 831 2.6E-16 T 29-03-2018 GBCGDNIH2_RS06120 4359a8264e29cecfbbe12c4c8ab39914 1148 Gene3D G3DSA:3.30.450.20 507 664 4.6E-5 T 29-03-2018 GBCGDNIH2_RS06120 4359a8264e29cecfbbe12c4c8ab39914 1148 Pfam PF01339 CheB methylesterase 23 198 1.6E-50 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 GBCGDNIH2_RS06120 4359a8264e29cecfbbe12c4c8ab39914 1148 Pfam PF13596 PAS domain 715 821 1.9E-17 T 29-03-2018 GBCGDNIH2_RS06120 4359a8264e29cecfbbe12c4c8ab39914 1148 Gene3D G3DSA:3.30.565.10 1011 1143 0.0042 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS06120 4359a8264e29cecfbbe12c4c8ab39914 1148 SUPERFAMILY SSF55785 820 946 4.36E-12 T 29-03-2018 IPR000014 PAS domain GBCGDNIH2_RS06120 4359a8264e29cecfbbe12c4c8ab39914 1148 SUPERFAMILY SSF53335 284 475 1.52E-45 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GBCGDNIH2_RS06120 4359a8264e29cecfbbe12c4c8ab39914 1148 SUPERFAMILY SSF47757 219 286 7.98E-13 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal GBCGDNIH2_RS06120 4359a8264e29cecfbbe12c4c8ab39914 1148 Gene3D G3DSA:1.20.5.1000 665 708 1.6E-8 T 29-03-2018 GBCGDNIH2_RS06120 4359a8264e29cecfbbe12c4c8ab39914 1148 Gene3D G3DSA:3.40.50.150 283 481 7.8E-42 T 29-03-2018 GBCGDNIH2_RS06120 4359a8264e29cecfbbe12c4c8ab39914 1148 Gene3D G3DSA:3.40.50.180 11 210 7.8E-61 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 GBCGDNIH2_RS06120 4359a8264e29cecfbbe12c4c8ab39914 1148 SUPERFAMILY SSF55785 700 821 2.97E-8 T 29-03-2018 IPR000014 PAS domain GBCGDNIH2_RS05685 b942374c6ca28656946ed24d37a00dba 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 250 1.4E-50 T 29-03-2018 GBCGDNIH2_RS05685 b942374c6ca28656946ed24d37a00dba 251 SUPERFAMILY SSF51735 7 250 7.35E-66 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS05685 b942374c6ca28656946ed24d37a00dba 251 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 GBCGDNIH2_RS05685 b942374c6ca28656946ed24d37a00dba 251 Gene3D G3DSA:3.40.50.10090 1 48 9.1E-9 T 29-03-2018 GBCGDNIH2_RS05685 b942374c6ca28656946ed24d37a00dba 251 Gene3D G3DSA:3.40.50.720 49 251 3.7E-51 T 29-03-2018 GBCGDNIH2_RS05685 b942374c6ca28656946ed24d37a00dba 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 2.4E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS05685 b942374c6ca28656946ed24d37a00dba 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 2.4E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS05685 b942374c6ca28656946ed24d37a00dba 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 2.4E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS05685 b942374c6ca28656946ed24d37a00dba 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 6.4E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS05685 b942374c6ca28656946ed24d37a00dba 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 6.4E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS05685 b942374c6ca28656946ed24d37a00dba 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 6.4E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS05685 b942374c6ca28656946ed24d37a00dba 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 6.4E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS05685 b942374c6ca28656946ed24d37a00dba 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 6.4E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS05685 b942374c6ca28656946ed24d37a00dba 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 6.4E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS05985 dc06aaf29543dccf4a68a8cc877a0e9d 158 Gene3D G3DSA:3.30.1330.60 32 155 3.1E-32 T 29-03-2018 IPR006665 OmpA-like domain GBCGDNIH2_RS05985 dc06aaf29543dccf4a68a8cc877a0e9d 158 SUPERFAMILY SSF103088 45 152 1.44E-31 T 29-03-2018 IPR006665 OmpA-like domain GBCGDNIH2_RS05985 dc06aaf29543dccf4a68a8cc877a0e9d 158 TIGRFAM TIGR02802 Pal_lipo: peptidoglycan-associated lipoprotein 54 155 1.1E-40 T 29-03-2018 IPR014169 Peptidoglycan-associated lipoprotein GO:0009279 GBCGDNIH2_RS05985 dc06aaf29543dccf4a68a8cc877a0e9d 158 PRINTS PR01021 OMPA domain signature 57 79 7.5E-15 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 GBCGDNIH2_RS05985 dc06aaf29543dccf4a68a8cc877a0e9d 158 PRINTS PR01021 OMPA domain signature 87 102 7.5E-15 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 GBCGDNIH2_RS05985 dc06aaf29543dccf4a68a8cc877a0e9d 158 PRINTS PR01021 OMPA domain signature 102 118 7.5E-15 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 GBCGDNIH2_RS05985 dc06aaf29543dccf4a68a8cc877a0e9d 158 Pfam PF00691 OmpA family 56 151 4.7E-19 T 29-03-2018 IPR006665 OmpA-like domain GBCGDNIH2_RS10755 879cb6dc740a950f017ee83570dca5fa 319 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 4 316 2.6E-120 T 29-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 GBCGDNIH2_RS10755 879cb6dc740a950f017ee83570dca5fa 319 Hamap MF_00536 4-hydroxythreonine-4-phosphate dehydrogenase [pdxA]. 1 316 33.273 T 29-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 GBCGDNIH2_RS10755 879cb6dc740a950f017ee83570dca5fa 319 SUPERFAMILY SSF53659 4 317 2.56E-103 T 29-03-2018 GBCGDNIH2_RS10755 879cb6dc740a950f017ee83570dca5fa 319 Gene3D G3DSA:3.40.718.10 2 319 1.2E-117 T 29-03-2018 GBCGDNIH2_RS10755 879cb6dc740a950f017ee83570dca5fa 319 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 53 312 4.3E-98 T 29-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 GBCGDNIH2_RS06575 b8dbc00aa0325806acd7a7f418f143da 956 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 5 924 0.0 T 29-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 GBCGDNIH2_RS06575 b8dbc00aa0325806acd7a7f418f143da 956 Hamap MF_00205 UvrABC system protein A [uvrA]. 2 939 22.309 T 29-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 GBCGDNIH2_RS06575 b8dbc00aa0325806acd7a7f418f143da 956 ProSitePatterns PS00211 ABC transporters family signature. 487 501 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GBCGDNIH2_RS06575 b8dbc00aa0325806acd7a7f418f143da 956 Gene3D G3DSA:1.10.8.280 285 391 6.3E-34 T 29-03-2018 GBCGDNIH2_RS06575 b8dbc00aa0325806acd7a7f418f143da 956 SUPERFAMILY SSF52540 617 909 7.45E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS06575 b8dbc00aa0325806acd7a7f418f143da 956 Gene3D G3DSA:3.40.50.300 9 36 0.27 T 29-03-2018 GBCGDNIH2_RS06575 b8dbc00aa0325806acd7a7f418f143da 956 ProSitePatterns PS00211 ABC transporters family signature. 829 843 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GBCGDNIH2_RS06575 b8dbc00aa0325806acd7a7f418f143da 956 Gene3D G3DSA:3.40.50.300 392 606 6.2E-27 T 29-03-2018 GBCGDNIH2_RS06575 b8dbc00aa0325806acd7a7f418f143da 956 Pfam PF00005 ABC transporter 790 859 2.7E-5 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GBCGDNIH2_RS06575 b8dbc00aa0325806acd7a7f418f143da 956 SUPERFAMILY SSF52540 431 569 5.77E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS06575 b8dbc00aa0325806acd7a7f418f143da 956 SUPERFAMILY SSF52540 6 205 5.77E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS06575 b8dbc00aa0325806acd7a7f418f143da 956 Gene3D G3DSA:3.40.50.300 607 945 1.7E-54 T 29-03-2018 GBCGDNIH2_RS06575 b8dbc00aa0325806acd7a7f418f143da 956 Gene3D G3DSA:3.40.50.300 37 72 4.1E-4 T 29-03-2018 GBCGDNIH2_RS06575 b8dbc00aa0325806acd7a7f418f143da 956 Gene3D G3DSA:3.30.190.20 128 247 8.9E-40 T 29-03-2018 GBCGDNIH2_RS04100 3b573cb87db64b812415dd3a6cd25a30 665 Pfam PF05170 AsmA family 21 560 1.2E-33 T 29-03-2018 IPR007844 AsmA GBCGDNIH2_RS00555 b3a21caebc059fd6508765c57aa3085f 1237 SUPERFAMILY SSF51730 195 558 4.71E-109 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like GBCGDNIH2_RS00555 b3a21caebc059fd6508765c57aa3085f 1237 SUPERFAMILY SSF81935 26 193 8.89E-55 T 29-03-2018 IPR024089 Proline dehydrogenase PutA, domain I/II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 GBCGDNIH2_RS00555 b3a21caebc059fd6508765c57aa3085f 1237 TIGRFAM TIGR01238 D1pyr5carbox3: delta-1-pyrroline-5-carboxylate dehydrogenase 551 1042 5.7E-200 T 29-03-2018 IPR005933 Delta-1-pyrroline-5-carboxylate dehydrogenase 3 GO:0003842|GO:0006561|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 GBCGDNIH2_RS00555 b3a21caebc059fd6508765c57aa3085f 1237 Pfam PF01619 Proline dehydrogenase 204 512 3.0E-95 T 29-03-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 GBCGDNIH2_RS00555 b3a21caebc059fd6508765c57aa3085f 1237 Gene3D G3DSA:3.40.605.10 585 837 7.2E-67 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 GBCGDNIH2_RS00555 b3a21caebc059fd6508765c57aa3085f 1237 Gene3D G3DSA:3.40.309.10 838 1021 3.2E-45 T 29-03-2018 GBCGDNIH2_RS00555 b3a21caebc059fd6508765c57aa3085f 1237 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 846 857 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 GBCGDNIH2_RS00555 b3a21caebc059fd6508765c57aa3085f 1237 Pfam PF00171 Aldehyde dehydrogenase family 595 1039 9.8E-109 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 GBCGDNIH2_RS00555 b3a21caebc059fd6508765c57aa3085f 1237 Gene3D G3DSA:3.20.20.220 25 119 9.1E-10 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like GBCGDNIH2_RS00555 b3a21caebc059fd6508765c57aa3085f 1237 Gene3D G3DSA:3.20.20.220 120 549 1.1E-100 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like GBCGDNIH2_RS00555 b3a21caebc059fd6508765c57aa3085f 1237 SUPERFAMILY SSF53720 594 1042 7.72E-120 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 GBCGDNIH2_RS00555 b3a21caebc059fd6508765c57aa3085f 1237 Pfam PF14850 DNA-binding domain of Proline dehydrogenase 81 192 5.7E-41 T 29-03-2018 IPR024082 Proline dehydrogenase PutA, domain II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 GBCGDNIH2_RS00555 b3a21caebc059fd6508765c57aa3085f 1237 PIRSF PIRSF000197 15 1237 0.0 T 29-03-2018 IPR025703 Bifunctional protein PutA GO:0003700|GO:0003842|GO:0004657|GO:0006355|GO:0010133 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 GBCGDNIH2_RS01235 04b538012b18b7c46c0849e6667e4554 406 Gene3D G3DSA:3.40.50.2000 221 386 2.5E-45 T 29-03-2018 GBCGDNIH2_RS01235 04b538012b18b7c46c0849e6667e4554 406 Pfam PF13439 Glycosyltransferase Family 4 103 206 4.4E-15 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 GBCGDNIH2_RS01235 04b538012b18b7c46c0849e6667e4554 406 Gene3D G3DSA:3.40.50.2000 10 220 1.4E-12 T 29-03-2018 GBCGDNIH2_RS01235 04b538012b18b7c46c0849e6667e4554 406 SUPERFAMILY SSF53756 102 403 6.78E-75 T 29-03-2018 GBCGDNIH2_RS01235 04b538012b18b7c46c0849e6667e4554 406 Pfam PF00534 Glycosyl transferases group 1 215 379 1.4E-39 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 GBCGDNIH2_RS05705 99aefe902f24a7d86a884153f0df73c3 204 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 203 29.125 T 29-03-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 GBCGDNIH2_RS05705 99aefe902f24a7d86a884153f0df73c3 204 Pfam PF02525 Flavodoxin-like fold 3 192 1.6E-38 T 29-03-2018 IPR003680 Flavodoxin-like fold GBCGDNIH2_RS05705 99aefe902f24a7d86a884153f0df73c3 204 SUPERFAMILY SSF52218 1 198 3.88E-47 T 29-03-2018 IPR029039 Flavoprotein-like domain GBCGDNIH2_RS05705 99aefe902f24a7d86a884153f0df73c3 204 Gene3D G3DSA:3.40.50.360 3 204 2.4E-35 T 29-03-2018 IPR029039 Flavoprotein-like domain GBCGDNIH2_RS02165 556a0740079cbda90845736d6fed0823 565 SUPERFAMILY SSF52540 1 217 8.2E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS02165 556a0740079cbda90845736d6fed0823 565 PIRSF PIRSF003128 1 565 4.0E-150 T 29-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 GBCGDNIH2_RS02165 556a0740079cbda90845736d6fed0823 565 Gene3D G3DSA:3.40.50.300 1 544 5.3E-38 T 29-03-2018 GBCGDNIH2_RS02165 556a0740079cbda90845736d6fed0823 565 Pfam PF02463 RecF/RecN/SMC N terminal domain 14 518 1.2E-17 T 29-03-2018 IPR003395 RecF/RecN/SMC, N-terminal GBCGDNIH2_RS02165 556a0740079cbda90845736d6fed0823 565 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 563 1.5E-142 T 29-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 GBCGDNIH2_RS02165 556a0740079cbda90845736d6fed0823 565 SUPERFAMILY SSF52540 318 509 3.58E-28 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS02165 556a0740079cbda90845736d6fed0823 565 SUPERFAMILY SSF52540 4 50 3.58E-28 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS00105 cfe2462b42d41941a198158970f4e8ab 374 Pfam PF00684 DnaJ central domain 145 206 7.8E-13 T 29-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 GBCGDNIH2_RS00105 cfe2462b42d41941a198158970f4e8ab 374 PRINTS PR00625 DnaJ domain signature 42 62 8.0E-33 T 29-03-2018 IPR001623 DnaJ domain GBCGDNIH2_RS00105 cfe2462b42d41941a198158970f4e8ab 374 PRINTS PR00625 DnaJ domain signature 62 81 8.0E-33 T 29-03-2018 IPR001623 DnaJ domain GBCGDNIH2_RS00105 cfe2462b42d41941a198158970f4e8ab 374 PRINTS PR00625 DnaJ domain signature 25 40 8.0E-33 T 29-03-2018 IPR001623 DnaJ domain GBCGDNIH2_RS00105 cfe2462b42d41941a198158970f4e8ab 374 PRINTS PR00625 DnaJ domain signature 7 25 8.0E-33 T 29-03-2018 IPR001623 DnaJ domain GBCGDNIH2_RS00105 cfe2462b42d41941a198158970f4e8ab 374 Gene3D G3DSA:1.10.287.110 1 111 8.7E-38 T 29-03-2018 IPR001623 DnaJ domain GBCGDNIH2_RS00105 cfe2462b42d41941a198158970f4e8ab 374 SMART SM00271 4 62 1.0E-30 T 29-03-2018 IPR001623 DnaJ domain GBCGDNIH2_RS00105 cfe2462b42d41941a198158970f4e8ab 374 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 2 370 40.918 T 29-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 GBCGDNIH2_RS00105 cfe2462b42d41941a198158970f4e8ab 374 Gene3D G3DSA:2.60.260.20 112 169 1.5E-11 T 29-03-2018 GBCGDNIH2_RS00105 cfe2462b42d41941a198158970f4e8ab 374 SUPERFAMILY SSF57938 132 210 1.57E-18 T 29-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 GBCGDNIH2_RS00105 cfe2462b42d41941a198158970f4e8ab 374 SUPERFAMILY SSF46565 1 104 5.89E-36 T 29-03-2018 IPR001623 DnaJ domain GBCGDNIH2_RS00105 cfe2462b42d41941a198158970f4e8ab 374 SUPERFAMILY SSF49493 258 344 4.06E-22 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 GBCGDNIH2_RS00105 cfe2462b42d41941a198158970f4e8ab 374 Pfam PF01556 DnaJ C terminal domain 119 333 2.1E-40 T 29-03-2018 IPR002939 Chaperone DnaJ, C-terminal GBCGDNIH2_RS00105 cfe2462b42d41941a198158970f4e8ab 374 Gene3D G3DSA:2.60.260.20 170 252 9.0E-20 T 29-03-2018 GBCGDNIH2_RS00105 cfe2462b42d41941a198158970f4e8ab 374 Gene3D G3DSA:2.60.260.20 253 364 1.0E-30 T 29-03-2018 GBCGDNIH2_RS00105 cfe2462b42d41941a198158970f4e8ab 374 SUPERFAMILY SSF49493 163 168 2.35E-20 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 GBCGDNIH2_RS00105 cfe2462b42d41941a198158970f4e8ab 374 SUPERFAMILY SSF49493 212 261 2.35E-20 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 GBCGDNIH2_RS00105 cfe2462b42d41941a198158970f4e8ab 374 SUPERFAMILY SSF49493 112 136 2.35E-20 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 GBCGDNIH2_RS00105 cfe2462b42d41941a198158970f4e8ab 374 ProSitePatterns PS00636 Nt-dnaJ domain signature. 47 66 - T 29-03-2018 IPR018253 DnaJ domain, conserved site GBCGDNIH2_RS00105 cfe2462b42d41941a198158970f4e8ab 374 Pfam PF00226 DnaJ domain 5 67 5.6E-27 T 29-03-2018 IPR001623 DnaJ domain GBCGDNIH2_RS00105 cfe2462b42d41941a198158970f4e8ab 374 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 5 350 2.8E-134 T 29-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 GBCGDNIH2_RS09050 4cba5b8df23533a532182876e747f335 910 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 15 66 3.2E-18 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS09050 4cba5b8df23533a532182876e747f335 910 Pfam PF00384 Molybdopterin oxidoreductase 70 492 8.6E-74 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS09050 4cba5b8df23533a532182876e747f335 910 SMART SM00926 13 67 1.2E-17 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS09050 4cba5b8df23533a532182876e747f335 910 Gene3D G3DSA:3.40.50.740 73 235 5.8E-44 T 29-03-2018 GBCGDNIH2_RS09050 4cba5b8df23533a532182876e747f335 910 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 18 36 - T 29-03-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 GBCGDNIH2_RS09050 4cba5b8df23533a532182876e747f335 910 Gene3D G3DSA:3.40.50.740 260 557 6.8E-74 T 29-03-2018 GBCGDNIH2_RS09050 4cba5b8df23533a532182876e747f335 910 Pfam PF04324 BFD-like [2Fe-2S] binding domain 850 898 1.0E-11 T 29-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain GBCGDNIH2_RS09050 4cba5b8df23533a532182876e747f335 910 Gene3D G3DSA:2.40.40.20 562 719 7.9E-43 T 29-03-2018 GBCGDNIH2_RS09050 4cba5b8df23533a532182876e747f335 910 Gene3D G3DSA:2.20.25.90 14 67 5.1E-19 T 29-03-2018 GBCGDNIH2_RS09050 4cba5b8df23533a532182876e747f335 910 Pfam PF01568 Molydopterin dinucleotide binding domain 597 707 3.3E-29 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 GBCGDNIH2_RS09050 4cba5b8df23533a532182876e747f335 910 SUPERFAMILY SSF53706 16 599 1.44E-179 T 29-03-2018 GBCGDNIH2_RS09050 4cba5b8df23533a532182876e747f335 910 PIRSF PIRSF036643 1 721 1.2E-141 T 29-03-2018 GBCGDNIH2_RS09050 4cba5b8df23533a532182876e747f335 910 SUPERFAMILY SSF50692 569 714 5.65E-43 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain GBCGDNIH2_RS05210 664e59727564cdd4029c11bc119d84ca 407 Gene3D G3DSA:3.90.1150.10 312 407 1.0E-20 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 GBCGDNIH2_RS05210 664e59727564cdd4029c11bc119d84ca 407 SUPERFAMILY SSF53383 25 405 2.55E-101 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase GBCGDNIH2_RS05210 664e59727564cdd4029c11bc119d84ca 407 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 250 263 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 GBCGDNIH2_RS05210 664e59727564cdd4029c11bc119d84ca 407 Pfam PF00155 Aminotransferase class I and II 49 400 6.5E-61 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 GBCGDNIH2_RS05210 664e59727564cdd4029c11bc119d84ca 407 Gene3D G3DSA:3.40.640.10 63 311 1.1E-57 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GBCGDNIH2_RS11995 704687ce277b13f9f5e294175b7ae995 191 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 107 117 - T 29-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 GBCGDNIH2_RS11995 704687ce277b13f9f5e294175b7ae995 191 Gene3D G3DSA:3.40.50.1470 1 189 4.2E-63 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 GBCGDNIH2_RS11995 704687ce277b13f9f5e294175b7ae995 191 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 2 184 8.8E-52 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 GBCGDNIH2_RS11995 704687ce277b13f9f5e294175b7ae995 191 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 1 178 31.507 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 GBCGDNIH2_RS11995 704687ce277b13f9f5e294175b7ae995 191 SUPERFAMILY SSF53178 2 184 3.01E-62 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 GBCGDNIH2_RS11995 704687ce277b13f9f5e294175b7ae995 191 Pfam PF01195 Peptidyl-tRNA hydrolase 5 183 1.2E-46 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 GBCGDNIH2_RS00935 1566dbb1f9d539c5d167cbde7b464f2d 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 224 3.7E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 GBCGDNIH2_RS00935 1566dbb1f9d539c5d167cbde7b464f2d 232 Pfam PF00072 Response regulator receiver domain 6 115 3.2E-32 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GBCGDNIH2_RS00935 1566dbb1f9d539c5d167cbde7b464f2d 232 SUPERFAMILY SSF52172 1 177 2.99E-43 T 29-03-2018 IPR011006 CheY-like superfamily GBCGDNIH2_RS00935 1566dbb1f9d539c5d167cbde7b464f2d 232 SMART SM00448 4 115 1.6E-43 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GBCGDNIH2_RS00935 1566dbb1f9d539c5d167cbde7b464f2d 232 SMART SM00862 150 224 2.3E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 GBCGDNIH2_RS00935 1566dbb1f9d539c5d167cbde7b464f2d 232 Gene3D G3DSA:3.40.50.2300 1 122 6.6E-40 T 29-03-2018 GBCGDNIH2_RS00935 1566dbb1f9d539c5d167cbde7b464f2d 232 Gene3D G3DSA:1.10.10.10 123 230 5.3E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS11715 284762aec3653c3ab9a8fe07ba6ea170 69 SMART SM00357 3 68 7.6E-21 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 GBCGDNIH2_RS11715 284762aec3653c3ab9a8fe07ba6ea170 69 SUPERFAMILY SSF50249 1 66 7.93E-22 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold GBCGDNIH2_RS11715 284762aec3653c3ab9a8fe07ba6ea170 69 Pfam PF00313 'Cold-shock' DNA-binding domain 3 62 3.4E-25 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 GBCGDNIH2_RS11715 284762aec3653c3ab9a8fe07ba6ea170 69 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 29-03-2018 IPR019844 Cold-shock conserved site GBCGDNIH2_RS11715 284762aec3653c3ab9a8fe07ba6ea170 69 Gene3D G3DSA:2.40.50.140 1 68 2.6E-24 T 29-03-2018 GBCGDNIH2_RS11715 284762aec3653c3ab9a8fe07ba6ea170 69 PIRSF PIRSF002599 1 69 4.0E-23 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 GBCGDNIH2_RS11715 284762aec3653c3ab9a8fe07ba6ea170 69 PRINTS PR00050 Cold shock protein signature 40 58 1.1E-15 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 GBCGDNIH2_RS11715 284762aec3653c3ab9a8fe07ba6ea170 69 PRINTS PR00050 Cold shock protein signature 25 34 1.1E-15 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 GBCGDNIH2_RS11715 284762aec3653c3ab9a8fe07ba6ea170 69 PRINTS PR00050 Cold shock protein signature 4 19 1.1E-15 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 GBCGDNIH2_RS08955 2078cee01465aa5f3a7d566120f01100 381 Pfam PF00696 Amino acid kinase family 20 246 1.7E-41 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase GBCGDNIH2_RS08955 2078cee01465aa5f3a7d566120f01100 381 Pfam PF01472 PUA domain 291 364 1.2E-19 T 29-03-2018 IPR002478 PUA domain GO:0003723 GBCGDNIH2_RS08955 2078cee01465aa5f3a7d566120f01100 381 Gene3D G3DSA:2.30.130.10 289 380 4.2E-26 T 29-03-2018 IPR002478 PUA domain GO:0003723 GBCGDNIH2_RS08955 2078cee01465aa5f3a7d566120f01100 381 Hamap MF_00456 Glutamate 5-kinase [proB]. 19 275 34.042 T 29-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 GBCGDNIH2_RS08955 2078cee01465aa5f3a7d566120f01100 381 PRINTS PR00474 Glutamate 5-kinase family signature 131 152 3.2E-46 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 GBCGDNIH2_RS08955 2078cee01465aa5f3a7d566120f01100 381 PRINTS PR00474 Glutamate 5-kinase family signature 57 71 3.2E-46 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 GBCGDNIH2_RS08955 2078cee01465aa5f3a7d566120f01100 381 PRINTS PR00474 Glutamate 5-kinase family signature 224 244 3.2E-46 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 GBCGDNIH2_RS08955 2078cee01465aa5f3a7d566120f01100 381 PRINTS PR00474 Glutamate 5-kinase family signature 91 119 3.2E-46 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 GBCGDNIH2_RS08955 2078cee01465aa5f3a7d566120f01100 381 PRINTS PR00474 Glutamate 5-kinase family signature 163 190 3.2E-46 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 GBCGDNIH2_RS08955 2078cee01465aa5f3a7d566120f01100 381 Gene3D G3DSA:3.40.1160.10 8 279 2.5E-59 T 29-03-2018 GBCGDNIH2_RS08955 2078cee01465aa5f3a7d566120f01100 381 SUPERFAMILY SSF88697 290 380 4.92E-25 T 29-03-2018 IPR015947 PUA-like domain GBCGDNIH2_RS08955 2078cee01465aa5f3a7d566120f01100 381 PIRSF PIRSF000729 14 381 2.7E-112 T 29-03-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 GBCGDNIH2_RS08955 2078cee01465aa5f3a7d566120f01100 381 SMART SM00359 291 373 3.1E-19 T 29-03-2018 IPR002478 PUA domain GO:0003723 GBCGDNIH2_RS08955 2078cee01465aa5f3a7d566120f01100 381 SUPERFAMILY SSF53633 19 270 4.84E-62 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase GBCGDNIH2_RS08955 2078cee01465aa5f3a7d566120f01100 381 TIGRFAM TIGR01027 proB: glutamate 5-kinase 19 379 3.1E-113 T 29-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 GBCGDNIH2_RS12090 dbcdacff8d11a866213926dd7ea860c3 308 Gene3D G3DSA:1.10.10.10 1 93 1.5E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS12090 dbcdacff8d11a866213926dd7ea860c3 308 SUPERFAMILY SSF53850 95 301 5.25E-39 T 29-03-2018 GBCGDNIH2_RS12090 dbcdacff8d11a866213926dd7ea860c3 308 SUPERFAMILY SSF46785 8 87 2.0E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS12090 dbcdacff8d11a866213926dd7ea860c3 308 Pfam PF03466 LysR substrate binding domain 104 300 1.7E-19 T 29-03-2018 IPR005119 LysR, substrate-binding GBCGDNIH2_RS12090 dbcdacff8d11a866213926dd7ea860c3 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 13 72 7.1E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS12090 dbcdacff8d11a866213926dd7ea860c3 308 Gene3D G3DSA:3.40.190.10 95 308 1.0E-20 T 29-03-2018 GBCGDNIH2_RS12090 dbcdacff8d11a866213926dd7ea860c3 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 49 3.6E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS12090 dbcdacff8d11a866213926dd7ea860c3 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 28 39 3.6E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS12090 dbcdacff8d11a866213926dd7ea860c3 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 49 60 3.6E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS11015 8135223f26e6ba6c7523191c206e4f6d 252 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 18 239 2.3E-55 T 29-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 GBCGDNIH2_RS11015 8135223f26e6ba6c7523191c206e4f6d 252 Pfam PF06508 Queuosine biosynthesis protein QueC 18 246 2.4E-68 T 29-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 GBCGDNIH2_RS11015 8135223f26e6ba6c7523191c206e4f6d 252 PIRSF PIRSF006293 14 252 5.4E-64 T 29-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 GBCGDNIH2_RS11015 8135223f26e6ba6c7523191c206e4f6d 252 Gene3D G3DSA:3.40.50.620 15 252 2.6E-41 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GBCGDNIH2_RS11015 8135223f26e6ba6c7523191c206e4f6d 252 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 16 252 47.229 T 29-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 GBCGDNIH2_RS11015 8135223f26e6ba6c7523191c206e4f6d 252 SUPERFAMILY SSF52402 17 246 7.81E-50 T 29-03-2018 GBCGDNIH2_RS00735 9450b121d11c370f5607b7373d6a7529 498 Gene3D G3DSA:3.30.565.10 332 483 2.5E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS00735 9450b121d11c370f5607b7373d6a7529 498 SMART SM00304 206 259 4.6E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 GBCGDNIH2_RS00735 9450b121d11c370f5607b7373d6a7529 498 Gene3D G3DSA:1.10.287.130 250 322 5.7E-5 T 29-03-2018 GBCGDNIH2_RS00735 9450b121d11c370f5607b7373d6a7529 498 SUPERFAMILY SSF47384 243 326 8.04E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GBCGDNIH2_RS00735 9450b121d11c370f5607b7373d6a7529 498 PRINTS PR00344 Bacterial sensor protein C-terminal signature 441 459 1.5E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS00735 9450b121d11c370f5607b7373d6a7529 498 PRINTS PR00344 Bacterial sensor protein C-terminal signature 408 422 1.5E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS00735 9450b121d11c370f5607b7373d6a7529 498 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 371 467 7.3E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS00735 9450b121d11c370f5607b7373d6a7529 498 SUPERFAMILY SSF158472 210 257 5.75E-7 T 29-03-2018 GBCGDNIH2_RS00735 9450b121d11c370f5607b7373d6a7529 498 SMART SM00387 371 480 4.8E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS00735 9450b121d11c370f5607b7373d6a7529 498 SUPERFAMILY SSF55874 316 476 1.83E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS00735 9450b121d11c370f5607b7373d6a7529 498 Pfam PF00672 HAMP domain 210 254 1.5E-7 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 GBCGDNIH2_RS00735 9450b121d11c370f5607b7373d6a7529 498 SMART SM00388 260 326 0.0012 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GBCGDNIH2_RS09675 ca154064fa7ad13a3ed21a7cc20ca752 672 SUPERFAMILY SSF48452 371 504 7.21E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS09675 ca154064fa7ad13a3ed21a7cc20ca752 672 SUPERFAMILY SSF48452 151 181 7.21E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS09675 ca154064fa7ad13a3ed21a7cc20ca752 672 Gene3D G3DSA:1.25.40.10 493 546 2.8E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS09675 ca154064fa7ad13a3ed21a7cc20ca752 672 Pfam PF09976 Tetratricopeptide repeat-like domain 407 504 5.3E-6 T 29-03-2018 IPR018704 Tetratricopeptide repeat-like domain Reactome: R-HSA-192823|Reactome: R-HSA-381038|Reactome: R-HSA-381426|Reactome: R-HSA-6798695|Reactome: R-HSA-8957275 GBCGDNIH2_RS09675 ca154064fa7ad13a3ed21a7cc20ca752 672 Gene3D G3DSA:1.25.40.10 278 422 6.6E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS09675 ca154064fa7ad13a3ed21a7cc20ca752 672 SMART SM00028 472 505 0.029 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 GBCGDNIH2_RS09675 ca154064fa7ad13a3ed21a7cc20ca752 672 SMART SM00028 144 179 320.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 GBCGDNIH2_RS09675 ca154064fa7ad13a3ed21a7cc20ca752 672 SMART SM00028 613 646 12.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 GBCGDNIH2_RS09675 ca154064fa7ad13a3ed21a7cc20ca752 672 SMART SM00028 438 471 450.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 GBCGDNIH2_RS09675 ca154064fa7ad13a3ed21a7cc20ca752 672 SMART SM00028 544 578 33.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 GBCGDNIH2_RS09675 ca154064fa7ad13a3ed21a7cc20ca752 672 SMART SM00028 510 543 8.2E-5 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 GBCGDNIH2_RS09675 ca154064fa7ad13a3ed21a7cc20ca752 672 SMART SM00028 579 612 3.5 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 GBCGDNIH2_RS09675 ca154064fa7ad13a3ed21a7cc20ca752 672 Pfam PF07719 Tetratricopeptide repeat 512 542 5.2E-5 T 29-03-2018 IPR013105 Tetratricopeptide repeat 2 GBCGDNIH2_RS09675 ca154064fa7ad13a3ed21a7cc20ca752 672 Gene3D G3DSA:1.25.40.10 423 492 1.5E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS09675 ca154064fa7ad13a3ed21a7cc20ca752 672 Pfam PF13432 Tetratricopeptide repeat 585 640 1.2E-7 T 29-03-2018 GBCGDNIH2_RS09675 ca154064fa7ad13a3ed21a7cc20ca752 672 Gene3D G3DSA:1.25.40.10 129 235 3.2E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS09675 ca154064fa7ad13a3ed21a7cc20ca752 672 Gene3D G3DSA:1.25.40.10 547 670 5.0E-27 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS09675 ca154064fa7ad13a3ed21a7cc20ca752 672 SUPERFAMILY SSF48452 469 646 1.99E-35 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS10220 4a331dd49f5abb09060144392f30034b 450 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 285 292 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 GBCGDNIH2_RS10220 4a331dd49f5abb09060144392f30034b 450 SUPERFAMILY SSF52440 1 113 8.63E-50 T 29-03-2018 IPR016185 Pre-ATP-grasp domain GBCGDNIH2_RS10220 4a331dd49f5abb09060144392f30034b 450 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 2.1E-45 T 29-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 GBCGDNIH2_RS10220 4a331dd49f5abb09060144392f30034b 450 SMART SM00878 335 440 6.3E-67 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 GBCGDNIH2_RS10220 4a331dd49f5abb09060144392f30034b 450 SUPERFAMILY SSF51246 330 442 2.2E-43 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 GBCGDNIH2_RS10220 4a331dd49f5abb09060144392f30034b 450 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 442 6.0E-215 T 29-03-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 GBCGDNIH2_RS10220 4a331dd49f5abb09060144392f30034b 450 Pfam PF02785 Biotin carboxylase C-terminal domain 335 440 4.4E-40 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 GBCGDNIH2_RS10220 4a331dd49f5abb09060144392f30034b 450 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 321 4.0E-81 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 GBCGDNIH2_RS10220 4a331dd49f5abb09060144392f30034b 450 Gene3D G3DSA:3.30.1490.20 124 209 8.4E-23 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 GBCGDNIH2_RS10220 4a331dd49f5abb09060144392f30034b 450 SUPERFAMILY SSF56059 83 345 5.66E-69 T 29-03-2018 GBCGDNIH2_RS10220 4a331dd49f5abb09060144392f30034b 450 Gene3D G3DSA:3.30.470.20 210 443 6.8E-98 T 29-03-2018 GBCGDNIH2_RS10220 4a331dd49f5abb09060144392f30034b 450 Gene3D G3DSA:3.40.50.20 1 123 1.2E-52 T 29-03-2018 GBCGDNIH2_RS10220 4a331dd49f5abb09060144392f30034b 450 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 GBCGDNIH2_RS09490 0fb63554fdb74fecf8d65234c8c18c69 412 Pfam PF13416 Bacterial extracellular solute-binding protein 54 378 5.9E-53 T 29-03-2018 GBCGDNIH2_RS09490 0fb63554fdb74fecf8d65234c8c18c69 412 SUPERFAMILY SSF53850 178 411 8.7E-27 T 29-03-2018 GBCGDNIH2_RS09490 0fb63554fdb74fecf8d65234c8c18c69 412 SUPERFAMILY SSF53850 49 130 8.7E-27 T 29-03-2018 GBCGDNIH2_RS09490 0fb63554fdb74fecf8d65234c8c18c69 412 Gene3D G3DSA:3.40.190.10 183 366 2.9E-13 T 29-03-2018 GBCGDNIH2_RS08660 2f6a4c89f4b07a95deb86804251a1e4d 127 Gene3D G3DSA:1.10.10.10 61 126 4.4E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS08660 2f6a4c89f4b07a95deb86804251a1e4d 127 Pfam PF00325 Bacterial regulatory proteins, crp family 105 124 5.5E-7 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 GBCGDNIH2_RS00870 50b9d8d77b13de4629289c0f728e1906 750 Pfam PF00593 TonB dependent receptor 301 749 4.1E-53 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 GBCGDNIH2_RS00870 50b9d8d77b13de4629289c0f728e1906 750 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 106 748 3.1E-101 T 29-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 GBCGDNIH2_RS00870 50b9d8d77b13de4629289c0f728e1906 750 Pfam PF07715 TonB-dependent Receptor Plug Domain 105 204 1.6E-18 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 GBCGDNIH2_RS00870 50b9d8d77b13de4629289c0f728e1906 750 SUPERFAMILY SSF56935 70 750 3.92E-120 T 29-03-2018 GBCGDNIH2_RS00870 50b9d8d77b13de4629289c0f728e1906 750 Gene3D G3DSA:2.170.130.10 61 212 8.0E-24 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 GBCGDNIH2_RS00870 50b9d8d77b13de4629289c0f728e1906 750 Gene3D G3DSA:2.40.170.20 218 750 7.0E-72 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 GBCGDNIH2_RS07060 4dc5ac981cd4ab099229efdc95350c0e 1037 SUPERFAMILY SSF82693 136 182 1.05E-19 T 29-03-2018 GBCGDNIH2_RS07060 4dc5ac981cd4ab099229efdc95350c0e 1037 SUPERFAMILY SSF82693 272 328 1.05E-19 T 29-03-2018 GBCGDNIH2_RS07060 4dc5ac981cd4ab099229efdc95350c0e 1037 Pfam PF00873 AcrB/AcrD/AcrF family 5 1016 3.8E-302 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS07060 4dc5ac981cd4ab099229efdc95350c0e 1037 PRINTS PR00702 Acriflavin resistance protein family signature 334 357 3.0E-77 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS07060 4dc5ac981cd4ab099229efdc95350c0e 1037 PRINTS PR00702 Acriflavin resistance protein family signature 361 382 3.0E-77 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS07060 4dc5ac981cd4ab099229efdc95350c0e 1037 PRINTS PR00702 Acriflavin resistance protein family signature 389 413 3.0E-77 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS07060 4dc5ac981cd4ab099229efdc95350c0e 1037 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 3.0E-77 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS07060 4dc5ac981cd4ab099229efdc95350c0e 1037 PRINTS PR00702 Acriflavin resistance protein family signature 442 465 3.0E-77 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS07060 4dc5ac981cd4ab099229efdc95350c0e 1037 PRINTS PR00702 Acriflavin resistance protein family signature 547 564 3.0E-77 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS07060 4dc5ac981cd4ab099229efdc95350c0e 1037 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 3.0E-77 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS07060 4dc5ac981cd4ab099229efdc95350c0e 1037 PRINTS PR00702 Acriflavin resistance protein family signature 467 490 3.0E-77 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS07060 4dc5ac981cd4ab099229efdc95350c0e 1037 PRINTS PR00702 Acriflavin resistance protein family signature 614 628 3.0E-77 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS07060 4dc5ac981cd4ab099229efdc95350c0e 1037 Gene3D G3DSA:3.30.2090.10 181 268 2.4E-15 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains GBCGDNIH2_RS07060 4dc5ac981cd4ab099229efdc95350c0e 1037 SUPERFAMILY SSF82866 294 494 8.24E-48 T 29-03-2018 GBCGDNIH2_RS07060 4dc5ac981cd4ab099229efdc95350c0e 1037 SUPERFAMILY SSF82866 797 1020 6.41E-41 T 29-03-2018 GBCGDNIH2_RS07060 4dc5ac981cd4ab099229efdc95350c0e 1037 Gene3D G3DSA:1.20.1640.10 284 502 4.6E-45 T 29-03-2018 GBCGDNIH2_RS07060 4dc5ac981cd4ab099229efdc95350c0e 1037 Gene3D G3DSA:1.20.1640.10 811 1029 7.5E-32 T 29-03-2018 GBCGDNIH2_RS07060 4dc5ac981cd4ab099229efdc95350c0e 1037 Gene3D G3DSA:3.30.70.1430 40 141 2.5E-21 T 29-03-2018 GBCGDNIH2_RS07060 4dc5ac981cd4ab099229efdc95350c0e 1037 SUPERFAMILY SSF82714 711 792 7.32E-15 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains GBCGDNIH2_RS07060 4dc5ac981cd4ab099229efdc95350c0e 1037 SUPERFAMILY SSF82714 184 265 1.11E-15 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains GBCGDNIH2_RS07060 4dc5ac981cd4ab099229efdc95350c0e 1037 SUPERFAMILY SSF82693 560 658 6.28E-11 T 29-03-2018 GBCGDNIH2_RS07060 4dc5ac981cd4ab099229efdc95350c0e 1037 Gene3D G3DSA:3.30.2090.10 709 795 1.9E-17 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains GBCGDNIH2_RS07060 4dc5ac981cd4ab099229efdc95350c0e 1037 SUPERFAMILY SSF82693 40 133 6.8E-20 T 29-03-2018 GBCGDNIH2_RS07060 4dc5ac981cd4ab099229efdc95350c0e 1037 Gene3D G3DSA:3.30.70.1430 562 660 3.3E-9 T 29-03-2018 GBCGDNIH2_RS11185 d9128209bc3cbfd8a286dccbfbf1367e 854 Pfam PF00535 Glycosyl transferase family 2 548 670 2.2E-14 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 GBCGDNIH2_RS11185 d9128209bc3cbfd8a286dccbfbf1367e 854 Pfam PF00535 Glycosyl transferase family 2 291 420 1.5E-24 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 GBCGDNIH2_RS11185 d9128209bc3cbfd8a286dccbfbf1367e 854 Gene3D G3DSA:3.90.550.10 257 529 1.7E-36 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS11185 d9128209bc3cbfd8a286dccbfbf1367e 854 Gene3D G3DSA:3.90.550.10 535 841 5.2E-41 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS11185 d9128209bc3cbfd8a286dccbfbf1367e 854 SUPERFAMILY SSF53448 544 791 1.41E-46 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS11185 d9128209bc3cbfd8a286dccbfbf1367e 854 SUPERFAMILY SSF53448 289 500 4.09E-47 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS01800 08b0e5f85372fc501b79527b5b4f3775 103 Pfam PF02315 Methanol dehydrogenase beta subunit 14 97 2.3E-41 T 29-03-2018 IPR003420 Methanol dehydrogenase, beta subunit GO:0004022|GO:0015946|GO:0055114 KEGG: 00010+1.1.2.7|KEGG: 00625+1.1.2.7|KEGG: 00680+1.1.2.7|MetaCyc: PWY-6966 GBCGDNIH2_RS01800 08b0e5f85372fc501b79527b5b4f3775 103 PIRSF PIRSF029163 2 99 7.3E-38 T 29-03-2018 IPR003420 Methanol dehydrogenase, beta subunit GO:0004022|GO:0015946|GO:0055114 KEGG: 00010+1.1.2.7|KEGG: 00625+1.1.2.7|KEGG: 00680+1.1.2.7|MetaCyc: PWY-6966 GBCGDNIH2_RS01800 08b0e5f85372fc501b79527b5b4f3775 103 SUPERFAMILY SSF48666 28 101 3.4E-35 T 29-03-2018 IPR003420 Methanol dehydrogenase, beta subunit GO:0004022|GO:0015946|GO:0055114 KEGG: 00010+1.1.2.7|KEGG: 00625+1.1.2.7|KEGG: 00680+1.1.2.7|MetaCyc: PWY-6966 GBCGDNIH2_RS01800 08b0e5f85372fc501b79527b5b4f3775 103 Gene3D G3DSA:4.10.160.10 28 98 3.7E-37 T 29-03-2018 IPR003420 Methanol dehydrogenase, beta subunit GO:0004022|GO:0015946|GO:0055114 KEGG: 00010+1.1.2.7|KEGG: 00625+1.1.2.7|KEGG: 00680+1.1.2.7|MetaCyc: PWY-6966 GBCGDNIH2_RS11530 eac101bce2c34c838e09d442f9fb9fb7 733 SUPERFAMILY SSF52540 479 596 5.94E-36 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS11530 eac101bce2c34c838e09d442f9fb9fb7 733 SUPERFAMILY SSF52540 53 102 5.94E-36 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS11530 eac101bce2c34c838e09d442f9fb9fb7 733 Pfam PF04851 Type III restriction enzyme, res subunit 35 159 3.8E-11 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 GBCGDNIH2_RS11530 eac101bce2c34c838e09d442f9fb9fb7 733 Gene3D G3DSA:3.40.50.300 435 609 1.0E-30 T 29-03-2018 GBCGDNIH2_RS11530 eac101bce2c34c838e09d442f9fb9fb7 733 SUPERFAMILY SSF46600 636 680 2.22E-10 T 29-03-2018 IPR001943 UVR domain GO:0005515 GBCGDNIH2_RS11530 eac101bce2c34c838e09d442f9fb9fb7 733 Gene3D G3DSA:3.40.50.300 31 433 5.8E-31 T 29-03-2018 GBCGDNIH2_RS11530 eac101bce2c34c838e09d442f9fb9fb7 733 Hamap MF_00204 UvrABC system protein B [uvrB]. 23 680 41.828 T 29-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 GBCGDNIH2_RS11530 eac101bce2c34c838e09d442f9fb9fb7 733 Gene3D G3DSA:4.10.860.10 611 682 3.6E-13 T 29-03-2018 IPR001943 UVR domain GO:0005515 GBCGDNIH2_RS11530 eac101bce2c34c838e09d442f9fb9fb7 733 Pfam PF12344 Ultra-violet resistance protein B 572 613 7.3E-19 T 29-03-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain GBCGDNIH2_RS11530 eac101bce2c34c838e09d442f9fb9fb7 733 SMART SM00487 29 445 3.4E-26 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain GBCGDNIH2_RS11530 eac101bce2c34c838e09d442f9fb9fb7 733 Pfam PF00271 Helicase conserved C-terminal domain 462 564 7.4E-18 T 29-03-2018 IPR001650 Helicase, C-terminal GBCGDNIH2_RS11530 eac101bce2c34c838e09d442f9fb9fb7 733 Pfam PF02151 UvrB/uvrC motif 647 679 3.5E-8 T 29-03-2018 IPR001943 UVR domain GO:0005515 GBCGDNIH2_RS11530 eac101bce2c34c838e09d442f9fb9fb7 733 SUPERFAMILY SSF52540 23 433 1.37E-132 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS11530 eac101bce2c34c838e09d442f9fb9fb7 733 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 26 677 0.0 T 29-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 GBCGDNIH2_RS11530 eac101bce2c34c838e09d442f9fb9fb7 733 SMART SM00490 480 566 3.2E-20 T 29-03-2018 IPR001650 Helicase, C-terminal GBCGDNIH2_RS09150 42f698e038837f84aefbb6704c8f36d9 1197 SUPERFAMILY SSF160467 796 886 1.24E-17 T 29-03-2018 GBCGDNIH2_RS09150 42f698e038837f84aefbb6704c8f36d9 1197 TIGRFAM TIGR02712 urea_carbox: urea carboxylase 2 1194 0.0 T 29-03-2018 IPR014084 Urea carboxylase KEGG: 00220+3.5.1.54+6.3.4.6|KEGG: 00791+3.5.1.54+6.3.4.6|MetaCyc: PWY-5169|MetaCyc: PWY-5703 GBCGDNIH2_RS09150 42f698e038837f84aefbb6704c8f36d9 1197 Gene3D G3DSA:3.30.1360.40 779 875 6.4E-24 T 29-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 GBCGDNIH2_RS09150 42f698e038837f84aefbb6704c8f36d9 1197 SUPERFAMILY SSF50891 910 1042 1.59E-26 T 29-03-2018 IPR029000 Cyclophilin-like domain GBCGDNIH2_RS09150 42f698e038837f84aefbb6704c8f36d9 1197 SUPERFAMILY SSF51246 328 441 3.45E-33 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 GBCGDNIH2_RS09150 42f698e038837f84aefbb6704c8f36d9 1197 SUPERFAMILY SSF51230 1120 1194 1.31E-20 T 29-03-2018 IPR011053 Single hybrid motif GBCGDNIH2_RS09150 42f698e038837f84aefbb6704c8f36d9 1197 SUPERFAMILY SSF52440 1 112 2.66E-46 T 29-03-2018 IPR016185 Pre-ATP-grasp domain GBCGDNIH2_RS09150 42f698e038837f84aefbb6704c8f36d9 1197 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 447 768 1.6E-84 T 29-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B GBCGDNIH2_RS09150 42f698e038837f84aefbb6704c8f36d9 1197 Gene3D G3DSA:3.40.50.20 1 123 2.2E-50 T 29-03-2018 GBCGDNIH2_RS09150 42f698e038837f84aefbb6704c8f36d9 1197 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 319 1.6E-62 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 GBCGDNIH2_RS09150 42f698e038837f84aefbb6704c8f36d9 1197 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 795 1015 5.6E-50 T 29-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D GBCGDNIH2_RS09150 42f698e038837f84aefbb6704c8f36d9 1197 SUPERFAMILY SSF56059 83 319 1.24E-62 T 29-03-2018 GBCGDNIH2_RS09150 42f698e038837f84aefbb6704c8f36d9 1197 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 GBCGDNIH2_RS09150 42f698e038837f84aefbb6704c8f36d9 1197 Pfam PF00364 Biotin-requiring enzyme 1129 1192 3.9E-17 T 29-03-2018 IPR000089 Biotin/lipoyl attachment GBCGDNIH2_RS09150 42f698e038837f84aefbb6704c8f36d9 1197 SMART SM00878 334 439 7.4E-48 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 GBCGDNIH2_RS09150 42f698e038837f84aefbb6704c8f36d9 1197 Gene3D G3DSA:3.30.1490.20 124 208 8.7E-17 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 GBCGDNIH2_RS09150 42f698e038837f84aefbb6704c8f36d9 1197 SUPERFAMILY SSF50891 625 751 3.79E-31 T 29-03-2018 IPR029000 Cyclophilin-like domain GBCGDNIH2_RS09150 42f698e038837f84aefbb6704c8f36d9 1197 Gene3D G3DSA:3.30.470.20 209 441 1.9E-91 T 29-03-2018 GBCGDNIH2_RS09150 42f698e038837f84aefbb6704c8f36d9 1197 SMART SM00797 470 761 9.9E-156 T 29-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B GBCGDNIH2_RS09150 42f698e038837f84aefbb6704c8f36d9 1197 SMART SM00796 793 1026 3.4E-110 T 29-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D GBCGDNIH2_RS09150 42f698e038837f84aefbb6704c8f36d9 1197 Gene3D G3DSA:2.40.100.10 881 1044 1.1E-49 T 29-03-2018 IPR029000 Cyclophilin-like domain GBCGDNIH2_RS09150 42f698e038837f84aefbb6704c8f36d9 1197 Gene3D G3DSA:2.40.50.100 1124 1195 9.0E-20 T 29-03-2018 GBCGDNIH2_RS09150 42f698e038837f84aefbb6704c8f36d9 1197 Pfam PF02785 Biotin carboxylase C-terminal domain 334 438 1.9E-33 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 GBCGDNIH2_RS09150 42f698e038837f84aefbb6704c8f36d9 1197 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 152 166 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 GBCGDNIH2_RS09150 42f698e038837f84aefbb6704c8f36d9 1197 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 471 744 1.3E-82 T 29-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B GBCGDNIH2_RS09150 42f698e038837f84aefbb6704c8f36d9 1197 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 1.2E-43 T 29-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 GBCGDNIH2_RS02905 d84fbfeabccb5e5f9f1986db63a62009 132 Gene3D G3DSA:3.30.1370.30 2 74 2.5E-19 T 29-03-2018 GBCGDNIH2_RS02905 d84fbfeabccb5e5f9f1986db63a62009 132 ProSitePatterns PS00053 Ribosomal protein S8 signature. 102 119 - T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02905 d84fbfeabccb5e5f9f1986db63a62009 132 Pfam PF00410 Ribosomal protein S8 5 132 3.1E-45 T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02905 d84fbfeabccb5e5f9f1986db63a62009 132 SUPERFAMILY SSF56047 4 132 1.01E-42 T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02905 d84fbfeabccb5e5f9f1986db63a62009 132 Gene3D G3DSA:3.30.1490.10 76 131 3.0E-22 T 29-03-2018 GBCGDNIH2_RS02905 d84fbfeabccb5e5f9f1986db63a62009 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 30.46 T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02825 4e8ac729e7604b410eee2ca753663797 396 Gene3D G3DSA:2.40.30.10 302 394 1.8E-31 T 29-03-2018 GBCGDNIH2_RS02825 4e8ac729e7604b410eee2ca753663797 396 Gene3D G3DSA:3.40.50.300 75 205 5.3E-29 T 29-03-2018 GBCGDNIH2_RS02825 4e8ac729e7604b410eee2ca753663797 396 Pfam PF03144 Elongation factor Tu domain 2 227 295 1.0E-17 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 GBCGDNIH2_RS02825 4e8ac729e7604b410eee2ca753663797 396 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 394 6.6E-229 T 29-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 GBCGDNIH2_RS02825 4e8ac729e7604b410eee2ca753663797 396 Pfam PF03143 Elongation factor Tu C-terminal domain 300 394 2.8E-33 T 29-03-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal GBCGDNIH2_RS02825 4e8ac729e7604b410eee2ca753663797 396 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 14 149 6.0E-14 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 GBCGDNIH2_RS02825 4e8ac729e7604b410eee2ca753663797 396 Gene3D G3DSA:3.40.50.300 2 74 2.0E-11 T 29-03-2018 GBCGDNIH2_RS02825 4e8ac729e7604b410eee2ca753663797 396 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site GBCGDNIH2_RS02825 4e8ac729e7604b410eee2ca753663797 396 PRINTS PR00315 GTP-binding elongation factor signature 94 105 2.4E-23 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GBCGDNIH2_RS02825 4e8ac729e7604b410eee2ca753663797 396 PRINTS PR00315 GTP-binding elongation factor signature 131 140 2.4E-23 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GBCGDNIH2_RS02825 4e8ac729e7604b410eee2ca753663797 396 PRINTS PR00315 GTP-binding elongation factor signature 78 88 2.4E-23 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GBCGDNIH2_RS02825 4e8ac729e7604b410eee2ca753663797 396 PRINTS PR00315 GTP-binding elongation factor signature 58 66 2.4E-23 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GBCGDNIH2_RS02825 4e8ac729e7604b410eee2ca753663797 396 PRINTS PR00315 GTP-binding elongation factor signature 14 27 2.4E-23 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GBCGDNIH2_RS02825 4e8ac729e7604b410eee2ca753663797 396 SUPERFAMILY SSF50465 304 395 2.23E-35 T 29-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal GBCGDNIH2_RS02825 4e8ac729e7604b410eee2ca753663797 396 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 9.5E-57 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GBCGDNIH2_RS02825 4e8ac729e7604b410eee2ca753663797 396 SUPERFAMILY SSF50447 205 303 4.71E-31 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain GBCGDNIH2_RS02825 4e8ac729e7604b410eee2ca753663797 396 Gene3D G3DSA:2.40.30.10 208 301 1.7E-31 T 29-03-2018 GBCGDNIH2_RS02825 4e8ac729e7604b410eee2ca753663797 396 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 60.342 T 29-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 GBCGDNIH2_RS02825 4e8ac729e7604b410eee2ca753663797 396 SUPERFAMILY SSF52540 9 228 1.18E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS11665 7008349f796fb4dc3877fb9ded0d1a79 502 SUPERFAMILY SSF55486 11 501 3.0E-105 T 29-03-2018 GBCGDNIH2_RS11665 7008349f796fb4dc3877fb9ded0d1a79 502 Pfam PF02074 Carboxypeptidase Taq (M32) metallopeptidase 16 499 4.2E-68 T 29-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 GBCGDNIH2_RS11665 7008349f796fb4dc3877fb9ded0d1a79 502 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 338 357 3.4E-41 T 29-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 GBCGDNIH2_RS11665 7008349f796fb4dc3877fb9ded0d1a79 502 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 153 173 3.4E-41 T 29-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 GBCGDNIH2_RS11665 7008349f796fb4dc3877fb9ded0d1a79 502 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 250 269 3.4E-41 T 29-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 GBCGDNIH2_RS11665 7008349f796fb4dc3877fb9ded0d1a79 502 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 297 313 3.4E-41 T 29-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 GBCGDNIH2_RS11665 7008349f796fb4dc3877fb9ded0d1a79 502 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 384 401 3.4E-41 T 29-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 GBCGDNIH2_RS11665 7008349f796fb4dc3877fb9ded0d1a79 502 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 452 470 3.4E-41 T 29-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 GBCGDNIH2_RS11665 7008349f796fb4dc3877fb9ded0d1a79 502 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 407 428 3.4E-41 T 29-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 GBCGDNIH2_RS11665 7008349f796fb4dc3877fb9ded0d1a79 502 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 270 289 3.4E-41 T 29-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 GBCGDNIH2_RS11665 7008349f796fb4dc3877fb9ded0d1a79 502 Gene3D G3DSA:1.10.1370.10 172 500 1.4E-28 T 29-03-2018 GBCGDNIH2_RS11665 7008349f796fb4dc3877fb9ded0d1a79 502 PIRSF PIRSF006615 8 502 6.3E-159 T 29-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 GBCGDNIH2_RS03200 f1000754dc63fd500eb5e8f2145fafdc 604 SUPERFAMILY SSF51120 354 446 7.59E-9 T 29-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal GBCGDNIH2_RS03200 f1000754dc63fd500eb5e8f2145fafdc 604 SUPERFAMILY SSF51120 490 590 7.59E-9 T 29-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal GBCGDNIH2_RS03200 f1000754dc63fd500eb5e8f2145fafdc 604 PRINTS PR00313 NodO calcium binding signature 493 501 5.6E-6 T 29-03-2018 GBCGDNIH2_RS03200 f1000754dc63fd500eb5e8f2145fafdc 604 PRINTS PR00313 NodO calcium binding signature 511 519 5.6E-6 T 29-03-2018 GBCGDNIH2_RS03200 f1000754dc63fd500eb5e8f2145fafdc 604 PRINTS PR00313 NodO calcium binding signature 429 440 5.6E-6 T 29-03-2018 GBCGDNIH2_RS03200 f1000754dc63fd500eb5e8f2145fafdc 604 PRINTS PR00313 NodO calcium binding signature 529 538 5.6E-6 T 29-03-2018 GBCGDNIH2_RS03200 f1000754dc63fd500eb5e8f2145fafdc 604 Gene3D G3DSA:2.150.10.10 383 460 0.0027 T 29-03-2018 GBCGDNIH2_RS03200 f1000754dc63fd500eb5e8f2145fafdc 604 Gene3D G3DSA:2.150.10.10 461 598 2.0E-15 T 29-03-2018 GBCGDNIH2_RS07995 3b5dfa2f4a47b7482a2a5b61492ed1ed 601 SUPERFAMILY SSF54980 298 375 6.47E-18 T 29-03-2018 IPR035647 EF-G domain III/V-like GBCGDNIH2_RS07995 3b5dfa2f4a47b7482a2a5b61492ed1ed 601 SUPERFAMILY SSF52540 5 237 1.12E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS07995 3b5dfa2f4a47b7482a2a5b61492ed1ed 601 SUPERFAMILY SSF54980 404 498 2.35E-25 T 29-03-2018 IPR035647 EF-G domain III/V-like GBCGDNIH2_RS07995 3b5dfa2f4a47b7482a2a5b61492ed1ed 601 TIGRFAM TIGR01393 lepA: elongation factor 4 8 600 1.6E-292 T 29-03-2018 IPR006297 Elongation factor 4 GO:0005525 GBCGDNIH2_RS07995 3b5dfa2f4a47b7482a2a5b61492ed1ed 601 SMART SM00838 403 488 0.0022 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like GBCGDNIH2_RS07995 3b5dfa2f4a47b7482a2a5b61492ed1ed 601 Pfam PF00679 Elongation factor G C-terminus 404 487 1.2E-21 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like GBCGDNIH2_RS07995 3b5dfa2f4a47b7482a2a5b61492ed1ed 601 Gene3D G3DSA:3.30.70.870 293 372 1.4E-26 T 29-03-2018 GBCGDNIH2_RS07995 3b5dfa2f4a47b7482a2a5b61492ed1ed 601 Gene3D G3DSA:3.40.50.300 6 196 5.8E-35 T 29-03-2018 GBCGDNIH2_RS07995 3b5dfa2f4a47b7482a2a5b61492ed1ed 601 Gene3D G3DSA:3.30.70.240 399 553 4.7E-27 T 29-03-2018 GBCGDNIH2_RS07995 3b5dfa2f4a47b7482a2a5b61492ed1ed 601 Hamap MF_00071 Elongation factor 4 [lepA]. 1 601 300.129 T 29-03-2018 IPR006297 Elongation factor 4 GO:0005525 GBCGDNIH2_RS07995 3b5dfa2f4a47b7482a2a5b61492ed1ed 601 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 10 179 2.3E-20 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 GBCGDNIH2_RS07995 3b5dfa2f4a47b7482a2a5b61492ed1ed 601 PRINTS PR00315 GTP-binding elongation factor signature 79 89 3.1E-13 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GBCGDNIH2_RS07995 3b5dfa2f4a47b7482a2a5b61492ed1ed 601 PRINTS PR00315 GTP-binding elongation factor signature 131 140 3.1E-13 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GBCGDNIH2_RS07995 3b5dfa2f4a47b7482a2a5b61492ed1ed 601 PRINTS PR00315 GTP-binding elongation factor signature 54 62 3.1E-13 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GBCGDNIH2_RS07995 3b5dfa2f4a47b7482a2a5b61492ed1ed 601 PRINTS PR00315 GTP-binding elongation factor signature 11 24 3.1E-13 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GBCGDNIH2_RS07995 3b5dfa2f4a47b7482a2a5b61492ed1ed 601 PRINTS PR00315 GTP-binding elongation factor signature 95 106 3.1E-13 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GBCGDNIH2_RS07995 3b5dfa2f4a47b7482a2a5b61492ed1ed 601 Gene3D G3DSA:2.40.30.10 197 292 2.2E-23 T 29-03-2018 GBCGDNIH2_RS07995 3b5dfa2f4a47b7482a2a5b61492ed1ed 601 Pfam PF03144 Elongation factor Tu domain 2 210 280 3.3E-10 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 GBCGDNIH2_RS07995 3b5dfa2f4a47b7482a2a5b61492ed1ed 601 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 47 62 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site GBCGDNIH2_RS07995 3b5dfa2f4a47b7482a2a5b61492ed1ed 601 Pfam PF06421 GTP-binding protein LepA C-terminus 492 598 4.5E-49 T 29-03-2018 IPR013842 GTP-binding protein LepA, C-terminal GBCGDNIH2_RS07995 3b5dfa2f4a47b7482a2a5b61492ed1ed 601 Pfam PF00009 Elongation factor Tu GTP binding domain 8 186 2.1E-51 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GBCGDNIH2_RS01385 37b15494f00af44ae987ae60ad2fb2c6 97 Pfam PF03795 YCII-related domain 1 84 8.5E-20 T 29-03-2018 IPR005545 YCII-related GBCGDNIH2_RS01385 37b15494f00af44ae987ae60ad2fb2c6 97 Gene3D G3DSA:3.30.70.1060 1 95 1.4E-23 T 29-03-2018 GBCGDNIH2_RS01385 37b15494f00af44ae987ae60ad2fb2c6 97 SUPERFAMILY SSF54909 1 90 4.56E-23 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel GBCGDNIH2_RS10545 cfbc4a00931568ea2a3711f3869e5a86 571 PRINTS PR00681 Ribosomal protein S1 signature 166 186 7.0E-84 T 29-03-2018 GBCGDNIH2_RS10545 cfbc4a00931568ea2a3711f3869e5a86 571 PRINTS PR00681 Ribosomal protein S1 signature 119 135 7.0E-84 T 29-03-2018 GBCGDNIH2_RS10545 cfbc4a00931568ea2a3711f3869e5a86 571 PRINTS PR00681 Ribosomal protein S1 signature 223 244 7.0E-84 T 29-03-2018 GBCGDNIH2_RS10545 cfbc4a00931568ea2a3711f3869e5a86 571 PRINTS PR00681 Ribosomal protein S1 signature 301 320 7.0E-84 T 29-03-2018 GBCGDNIH2_RS10545 cfbc4a00931568ea2a3711f3869e5a86 571 PRINTS PR00681 Ribosomal protein S1 signature 50 64 7.0E-84 T 29-03-2018 GBCGDNIH2_RS10545 cfbc4a00931568ea2a3711f3869e5a86 571 PRINTS PR00681 Ribosomal protein S1 signature 341 359 7.0E-84 T 29-03-2018 GBCGDNIH2_RS10545 cfbc4a00931568ea2a3711f3869e5a86 571 PRINTS PR00681 Ribosomal protein S1 signature 32 50 7.0E-84 T 29-03-2018 GBCGDNIH2_RS10545 cfbc4a00931568ea2a3711f3869e5a86 571 PRINTS PR00681 Ribosomal protein S1 signature 95 114 7.0E-84 T 29-03-2018 GBCGDNIH2_RS10545 cfbc4a00931568ea2a3711f3869e5a86 571 PRINTS PR00681 Ribosomal protein S1 signature 137 154 7.0E-84 T 29-03-2018 GBCGDNIH2_RS10545 cfbc4a00931568ea2a3711f3869e5a86 571 Gene3D G3DSA:2.40.50.140 107 188 1.0E-5 T 29-03-2018 GBCGDNIH2_RS10545 cfbc4a00931568ea2a3711f3869e5a86 571 Gene3D G3DSA:2.40.50.140 196 277 1.6E-26 T 29-03-2018 GBCGDNIH2_RS10545 cfbc4a00931568ea2a3711f3869e5a86 571 SUPERFAMILY SSF50249 266 375 4.33E-27 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold GBCGDNIH2_RS10545 cfbc4a00931568ea2a3711f3869e5a86 571 SUPERFAMILY SSF50249 20 123 6.55E-18 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold GBCGDNIH2_RS10545 cfbc4a00931568ea2a3711f3869e5a86 571 Gene3D G3DSA:2.40.50.140 375 459 6.2E-19 T 29-03-2018 GBCGDNIH2_RS10545 cfbc4a00931568ea2a3711f3869e5a86 571 SMART SM00316 460 531 1.8E-14 T 29-03-2018 IPR022967 RNA-binding domain, S1 GBCGDNIH2_RS10545 cfbc4a00931568ea2a3711f3869e5a86 571 SMART SM00316 373 445 6.8E-18 T 29-03-2018 IPR022967 RNA-binding domain, S1 GBCGDNIH2_RS10545 cfbc4a00931568ea2a3711f3869e5a86 571 SMART SM00316 30 98 4.0E-9 T 29-03-2018 IPR022967 RNA-binding domain, S1 GBCGDNIH2_RS10545 cfbc4a00931568ea2a3711f3869e5a86 571 SMART SM00316 286 358 9.1E-25 T 29-03-2018 IPR022967 RNA-binding domain, S1 GBCGDNIH2_RS10545 cfbc4a00931568ea2a3711f3869e5a86 571 SMART SM00316 201 271 2.6E-28 T 29-03-2018 IPR022967 RNA-binding domain, S1 GBCGDNIH2_RS10545 cfbc4a00931568ea2a3711f3869e5a86 571 SMART SM00316 114 182 5.5E-4 T 29-03-2018 IPR022967 RNA-binding domain, S1 GBCGDNIH2_RS10545 cfbc4a00931568ea2a3711f3869e5a86 571 Gene3D G3DSA:2.40.50.140 286 359 2.3E-24 T 29-03-2018 GBCGDNIH2_RS10545 cfbc4a00931568ea2a3711f3869e5a86 571 Gene3D G3DSA:2.40.50.140 460 540 1.4E-16 T 29-03-2018 GBCGDNIH2_RS10545 cfbc4a00931568ea2a3711f3869e5a86 571 Gene3D G3DSA:2.40.50.140 31 106 6.8E-10 T 29-03-2018 GBCGDNIH2_RS10545 cfbc4a00931568ea2a3711f3869e5a86 571 Pfam PF00575 S1 RNA binding domain 462 531 1.8E-12 T 29-03-2018 IPR003029 S1 domain GO:0003676 GBCGDNIH2_RS10545 cfbc4a00931568ea2a3711f3869e5a86 571 Pfam PF00575 S1 RNA binding domain 114 182 1.1E-10 T 29-03-2018 IPR003029 S1 domain GO:0003676 GBCGDNIH2_RS10545 cfbc4a00931568ea2a3711f3869e5a86 571 Pfam PF00575 S1 RNA binding domain 31 97 9.1E-7 T 29-03-2018 IPR003029 S1 domain GO:0003676 GBCGDNIH2_RS10545 cfbc4a00931568ea2a3711f3869e5a86 571 Pfam PF00575 S1 RNA binding domain 201 271 1.7E-20 T 29-03-2018 IPR003029 S1 domain GO:0003676 GBCGDNIH2_RS10545 cfbc4a00931568ea2a3711f3869e5a86 571 Pfam PF00575 S1 RNA binding domain 372 445 2.7E-15 T 29-03-2018 IPR003029 S1 domain GO:0003676 GBCGDNIH2_RS10545 cfbc4a00931568ea2a3711f3869e5a86 571 Pfam PF00575 S1 RNA binding domain 286 358 1.2E-19 T 29-03-2018 IPR003029 S1 domain GO:0003676 GBCGDNIH2_RS10545 cfbc4a00931568ea2a3711f3869e5a86 571 TIGRFAM TIGR00717 rpsA: ribosomal protein bS1 14 531 1.3E-193 T 29-03-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 GBCGDNIH2_RS10545 cfbc4a00931568ea2a3711f3869e5a86 571 SUPERFAMILY SSF50249 200 287 3.07E-26 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold GBCGDNIH2_RS10545 cfbc4a00931568ea2a3711f3869e5a86 571 PIRSF PIRSF002111 1 545 1.7E-199 T 29-03-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 GBCGDNIH2_RS10545 cfbc4a00931568ea2a3711f3869e5a86 571 SUPERFAMILY SSF50249 440 544 5.22E-18 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold GBCGDNIH2_RS10545 cfbc4a00931568ea2a3711f3869e5a86 571 SUPERFAMILY SSF50249 358 450 1.42E-19 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold GBCGDNIH2_RS10545 cfbc4a00931568ea2a3711f3869e5a86 571 SUPERFAMILY SSF50249 117 196 8.58E-13 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold GBCGDNIH2_RS04080 6b709ca96ab17299363aeaed31c6993a 150 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 5 58 4.6E-7 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 GBCGDNIH2_RS04080 6b709ca96ab17299363aeaed31c6993a 150 Gene3D G3DSA:1.10.150.120 74 150 2.1E-28 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 GBCGDNIH2_RS04080 6b709ca96ab17299363aeaed31c6993a 150 SUPERFAMILY SSF54292 2 77 8.0E-25 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 GBCGDNIH2_RS04080 6b709ca96ab17299363aeaed31c6993a 150 SUPERFAMILY SSF47741 81 149 9.16E-29 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 GBCGDNIH2_RS04080 6b709ca96ab17299363aeaed31c6993a 150 Pfam PF01799 [2Fe-2S] binding domain 72 145 3.1E-26 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 GBCGDNIH2_RS04080 6b709ca96ab17299363aeaed31c6993a 150 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 38 46 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 GBCGDNIH2_RS04080 6b709ca96ab17299363aeaed31c6993a 150 Gene3D G3DSA:3.10.20.30 1 73 2.5E-23 T 29-03-2018 IPR012675 Beta-grasp domain GBCGDNIH2_RS03150 ac681da796b41d63e05760818334485d 290 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 3 285 51.779 T 29-03-2018 IPR023009 Tyrosine recombinase XerC/XerD GBCGDNIH2_RS03150 ac681da796b41d63e05760818334485d 290 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 5 87 1.5E-17 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 GBCGDNIH2_RS03150 ac681da796b41d63e05760818334485d 290 SUPERFAMILY SSF56349 5 277 1.03E-51 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 GBCGDNIH2_RS03150 ac681da796b41d63e05760818334485d 290 Gene3D G3DSA:1.10.443.10 109 279 4.8E-42 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 GBCGDNIH2_RS03150 ac681da796b41d63e05760818334485d 290 Gene3D G3DSA:1.10.150.130 1 108 4.0E-23 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal GBCGDNIH2_RS03150 ac681da796b41d63e05760818334485d 290 Pfam PF00589 Phage integrase family 108 270 4.5E-40 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 GBCGDNIH2_RS08110 2997546751c2daaf2768a318bf97bd19 736 Pfam PF00664 ABC transporter transmembrane region 198 451 6.8E-19 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 GBCGDNIH2_RS08110 2997546751c2daaf2768a318bf97bd19 736 Gene3D G3DSA:3.90.70.10 30 158 2.6E-41 T 29-03-2018 GBCGDNIH2_RS08110 2997546751c2daaf2768a318bf97bd19 736 ProSitePatterns PS00211 ABC transporters family signature. 640 654 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GBCGDNIH2_RS08110 2997546751c2daaf2768a318bf97bd19 736 SUPERFAMILY SSF90123 167 480 1.83E-43 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 GBCGDNIH2_RS08110 2997546751c2daaf2768a318bf97bd19 736 Pfam PF00005 ABC transporter 520 668 3.0E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GBCGDNIH2_RS08110 2997546751c2daaf2768a318bf97bd19 736 SUPERFAMILY SSF52540 498 734 2.25E-74 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS08110 2997546751c2daaf2768a318bf97bd19 736 Gene3D G3DSA:1.20.1560.10 159 484 2.4E-34 T 29-03-2018 GBCGDNIH2_RS08110 2997546751c2daaf2768a318bf97bd19 736 TIGRFAM TIGR03796 NHLM_micro_ABC1: NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein 27 734 1.1E-300 T 29-03-2018 IPR022514 NHPM bacteriocin system ABC transporter, peptidase/ATP-binding protein GBCGDNIH2_RS08110 2997546751c2daaf2768a318bf97bd19 736 Gene3D G3DSA:3.40.50.300 489 736 2.9E-65 T 29-03-2018 GBCGDNIH2_RS08110 2997546751c2daaf2768a318bf97bd19 736 Pfam PF03412 Peptidase C39 family 28 156 3.1E-38 T 29-03-2018 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 GBCGDNIH2_RS08110 2997546751c2daaf2768a318bf97bd19 736 SMART SM00382 528 718 6.1E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS02100 ce6d98ee149969b19453f8ca6f72062a 219 Pfam PF03379 CcmB protein 3 215 3.4E-62 T 29-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 GBCGDNIH2_RS02100 ce6d98ee149969b19453f8ca6f72062a 219 PIRSF PIRSF002764 1 219 1.7E-65 T 29-03-2018 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria GBCGDNIH2_RS02100 ce6d98ee149969b19453f8ca6f72062a 219 TIGRFAM TIGR01190 ccmB: heme exporter protein CcmB 5 215 1.1E-62 T 29-03-2018 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria GBCGDNIH2_RS02100 ce6d98ee149969b19453f8ca6f72062a 219 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 192 215 1.6E-50 T 29-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 GBCGDNIH2_RS02100 ce6d98ee149969b19453f8ca6f72062a 219 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 52 69 1.6E-50 T 29-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 GBCGDNIH2_RS02100 ce6d98ee149969b19453f8ca6f72062a 219 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 155 174 1.6E-50 T 29-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 GBCGDNIH2_RS02100 ce6d98ee149969b19453f8ca6f72062a 219 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 26 47 1.6E-50 T 29-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 GBCGDNIH2_RS02100 ce6d98ee149969b19453f8ca6f72062a 219 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 100 118 1.6E-50 T 29-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 GBCGDNIH2_RS02100 ce6d98ee149969b19453f8ca6f72062a 219 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 75 98 1.6E-50 T 29-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 GBCGDNIH2_RS12570 6b3ec5526dcf5fd7b162064e1b0679b7 294 Gene3D G3DSA:3.40.50.150 1 277 1.3E-69 T 29-03-2018 GBCGDNIH2_RS12570 6b3ec5526dcf5fd7b162064e1b0679b7 294 Hamap MF_00934 Ribosomal RNA large subunit methyltransferase J [rlmJ]. 1 269 37.782 T 29-03-2018 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 GBCGDNIH2_RS12570 6b3ec5526dcf5fd7b162064e1b0679b7 294 Pfam PF04378 Ribosomal RNA large subunit methyltransferase D, RlmJ 32 268 9.9E-67 T 29-03-2018 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 GBCGDNIH2_RS12570 6b3ec5526dcf5fd7b162064e1b0679b7 294 SUPERFAMILY SSF53335 8 267 6.37E-71 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GBCGDNIH2_RS11745 21cc3873aecbc580b5fdb914e71481d5 231 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 114 193 8.8E-6 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 GBCGDNIH2_RS11745 21cc3873aecbc580b5fdb914e71481d5 231 Gene3D G3DSA:3.40.50.1000 5 225 7.8E-13 T 29-03-2018 IPR023214 HAD-like domain GBCGDNIH2_RS11745 21cc3873aecbc580b5fdb914e71481d5 231 SUPERFAMILY SSF56784 1 208 1.29E-54 T 29-03-2018 IPR023214 HAD-like domain GBCGDNIH2_RS11745 21cc3873aecbc580b5fdb914e71481d5 231 Hamap MF_01681 Enolase-phosphatase E1 [mtnC]. 3 222 41.249 T 29-03-2018 IPR023943 Enolase-phosphatase E1 GO:0000287|GO:0019509|GO:0043874 KEGG: 00270+3.1.3.77|Reactome: R-HSA-1237112 GBCGDNIH2_RS11745 21cc3873aecbc580b5fdb914e71481d5 231 TIGRFAM TIGR01691 enolase-ppase: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase 5 209 2.6E-76 T 29-03-2018 IPR023943 Enolase-phosphatase E1 GO:0000287|GO:0019509|GO:0043874 KEGG: 00270+3.1.3.77|Reactome: R-HSA-1237112 GBCGDNIH2_RS09590 75d750f98a318751e9a42275c0e6dda3 229 SUPERFAMILY SSF52540 2 219 1.96E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS09590 75d750f98a318751e9a42275c0e6dda3 229 Gene3D G3DSA:3.40.50.300 1 228 1.6E-59 T 29-03-2018 GBCGDNIH2_RS09590 75d750f98a318751e9a42275c0e6dda3 229 TIGRFAM TIGR03410 urea_trans_UrtE: urea ABC transporter, ATP-binding protein UrtE 2 229 2.8E-99 T 29-03-2018 IPR017780 ABC transporter, urea, ATP-binding protein, UrtE GBCGDNIH2_RS09590 75d750f98a318751e9a42275c0e6dda3 229 SMART SM00382 26 208 4.2E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS09590 75d750f98a318751e9a42275c0e6dda3 229 Pfam PF00005 ABC transporter 17 158 5.1E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GBCGDNIH2_RS09995 76de00b38959ec4f86eac83cc359457f 420 SUPERFAMILY SSF53822 78 383 8.41E-20 T 29-03-2018 IPR028082 Periplasmic binding protein-like I GBCGDNIH2_RS09995 76de00b38959ec4f86eac83cc359457f 420 Gene3D G3DSA:3.40.50.2300 35 379 7.5E-12 T 29-03-2018 GBCGDNIH2_RS09995 76de00b38959ec4f86eac83cc359457f 420 TIGRFAM TIGR03863 PQQ_ABC_bind: ABC transporter, substrate binding protein, PQQ-dependent alcohol dehydrogenase system 68 418 2.0E-152 T 29-03-2018 IPR022478 ABC transporter, substrate-binding protein, PQQ-dependent alcohol dehydrogenase system GBCGDNIH2_RS07195 40d1c8a5219a9cf756b488a14b8e7591 239 SUPERFAMILY SSF48150 42 211 1.92E-39 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 GBCGDNIH2_RS07195 40d1c8a5219a9cf756b488a14b8e7591 239 SMART SM00478 57 214 3.8E-14 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 GBCGDNIH2_RS07195 40d1c8a5219a9cf756b488a14b8e7591 239 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 53 195 5.1E-14 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 GBCGDNIH2_RS07195 40d1c8a5219a9cf756b488a14b8e7591 239 Gene3D G3DSA:1.10.340.30 16 177 1.8E-28 T 29-03-2018 GBCGDNIH2_RS07195 40d1c8a5219a9cf756b488a14b8e7591 239 Gene3D G3DSA:1.10.1670.10 178 218 3.1E-16 T 29-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 GBCGDNIH2_RS12100 8792090f6a9bb3a670ed1f2baefa5e36 417 ProSitePatterns PS00810 ADP-glucose pyrophosphorylase signature 3. 202 212 - T 29-03-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 GBCGDNIH2_RS12100 8792090f6a9bb3a670ed1f2baefa5e36 417 SUPERFAMILY SSF53448 12 285 1.99E-76 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS12100 8792090f6a9bb3a670ed1f2baefa5e36 417 SUPERFAMILY SSF53448 369 384 1.99E-76 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS12100 8792090f6a9bb3a670ed1f2baefa5e36 417 Gene3D G3DSA:2.160.10.10 305 396 4.2E-6 T 29-03-2018 GBCGDNIH2_RS12100 8792090f6a9bb3a670ed1f2baefa5e36 417 Pfam PF00483 Nucleotidyl transferase 14 282 1.3E-65 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 GBCGDNIH2_RS12100 8792090f6a9bb3a670ed1f2baefa5e36 417 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 12 388 4.4E-151 T 29-03-2018 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 GBCGDNIH2_RS12100 8792090f6a9bb3a670ed1f2baefa5e36 417 Hamap MF_00624 Glucose-1-phosphate adenylyltransferase [glgC]. 8 414 51.255 T 29-03-2018 IPR023049 Glucose-1-phosphate adenylyltransferase GlgC, bacterial GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 GBCGDNIH2_RS12100 8792090f6a9bb3a670ed1f2baefa5e36 417 SUPERFAMILY SSF51161 301 399 9.64E-14 T 29-03-2018 IPR011004 Trimeric LpxA-like GBCGDNIH2_RS12100 8792090f6a9bb3a670ed1f2baefa5e36 417 ProSitePatterns PS00808 ADP-glucose pyrophosphorylase signature 1. 17 36 - T 29-03-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 GBCGDNIH2_RS12100 8792090f6a9bb3a670ed1f2baefa5e36 417 Gene3D G3DSA:3.90.550.10 11 304 4.8E-67 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS12100 8792090f6a9bb3a670ed1f2baefa5e36 417 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 104 112 - T 29-03-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 GBCGDNIH2_RS03120 d2ac7a52d8388d1afbcfdcc902816e59 306 Pfam PF00293 NUDIX domain 140 261 3.5E-7 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 GBCGDNIH2_RS03120 d2ac7a52d8388d1afbcfdcc902816e59 306 SUPERFAMILY SSF55811 117 281 3.5E-17 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 GBCGDNIH2_RS03120 d2ac7a52d8388d1afbcfdcc902816e59 306 Pfam PF15916 Domain of unknown function (DUF4743) 38 136 2.6E-6 T 29-03-2018 IPR031804 Domain of unknown function DUF4743 GBCGDNIH2_RS03120 d2ac7a52d8388d1afbcfdcc902816e59 306 Gene3D G3DSA:3.90.79.10 121 300 1.7E-22 T 29-03-2018 GBCGDNIH2_RS07065 a9e895ee12ff3d1618785e0f7ef59406 1066 SUPERFAMILY SSF82693 40 134 1.23E-20 T 29-03-2018 GBCGDNIH2_RS07065 a9e895ee12ff3d1618785e0f7ef59406 1066 SUPERFAMILY SSF82866 828 1053 2.75E-44 T 29-03-2018 GBCGDNIH2_RS07065 a9e895ee12ff3d1618785e0f7ef59406 1066 SUPERFAMILY SSF82693 559 654 2.2E-11 T 29-03-2018 GBCGDNIH2_RS07065 a9e895ee12ff3d1618785e0f7ef59406 1066 SUPERFAMILY SSF82866 290 491 7.72E-46 T 29-03-2018 GBCGDNIH2_RS07065 a9e895ee12ff3d1618785e0f7ef59406 1066 SUPERFAMILY SSF82714 710 784 1.24E-11 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains GBCGDNIH2_RS07065 a9e895ee12ff3d1618785e0f7ef59406 1066 Gene3D G3DSA:3.30.70.1430 40 142 7.7E-22 T 29-03-2018 GBCGDNIH2_RS07065 a9e895ee12ff3d1618785e0f7ef59406 1066 Pfam PF00873 AcrB/AcrD/AcrF family 7 1050 7.7E-287 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS07065 a9e895ee12ff3d1618785e0f7ef59406 1066 Gene3D G3DSA:3.30.70.1430 562 660 1.6E-12 T 29-03-2018 GBCGDNIH2_RS07065 a9e895ee12ff3d1618785e0f7ef59406 1066 Gene3D G3DSA:3.30.2090.10 181 266 1.5E-11 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains GBCGDNIH2_RS07065 a9e895ee12ff3d1618785e0f7ef59406 1066 Gene3D G3DSA:1.20.1640.10 267 493 3.7E-46 T 29-03-2018 GBCGDNIH2_RS07065 a9e895ee12ff3d1618785e0f7ef59406 1066 Gene3D G3DSA:1.20.1640.10 851 1053 1.5E-36 T 29-03-2018 GBCGDNIH2_RS07065 a9e895ee12ff3d1618785e0f7ef59406 1066 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 1.3E-67 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS07065 a9e895ee12ff3d1618785e0f7ef59406 1066 PRINTS PR00702 Acriflavin resistance protein family signature 613 627 1.3E-67 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS07065 a9e895ee12ff3d1618785e0f7ef59406 1066 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 1.3E-67 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS07065 a9e895ee12ff3d1618785e0f7ef59406 1066 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 1.3E-67 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS07065 a9e895ee12ff3d1618785e0f7ef59406 1066 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 1.3E-67 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS07065 a9e895ee12ff3d1618785e0f7ef59406 1066 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 1.3E-67 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS07065 a9e895ee12ff3d1618785e0f7ef59406 1066 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 1.3E-67 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS07065 a9e895ee12ff3d1618785e0f7ef59406 1066 PRINTS PR00702 Acriflavin resistance protein family signature 546 563 1.3E-67 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS07065 a9e895ee12ff3d1618785e0f7ef59406 1066 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 1.3E-67 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS07065 a9e895ee12ff3d1618785e0f7ef59406 1066 SUPERFAMILY SSF82714 183 265 1.31E-12 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains GBCGDNIH2_RS07065 a9e895ee12ff3d1618785e0f7ef59406 1066 Gene3D G3DSA:3.30.2090.10 709 831 1.7E-15 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains GBCGDNIH2_RS07065 a9e895ee12ff3d1618785e0f7ef59406 1066 SUPERFAMILY SSF82693 138 182 9.42E-25 T 29-03-2018 GBCGDNIH2_RS07065 a9e895ee12ff3d1618785e0f7ef59406 1066 SUPERFAMILY SSF82693 268 324 9.42E-25 T 29-03-2018 GBCGDNIH2_RS02755 87e96479c7ce8fa6c250e9392e0b1c5d 350 Pfam PF13439 Glycosyltransferase Family 4 18 121 3.9E-9 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 GBCGDNIH2_RS02755 87e96479c7ce8fa6c250e9392e0b1c5d 350 Pfam PF00534 Glycosyl transferases group 1 169 309 3.8E-22 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 GBCGDNIH2_RS02755 87e96479c7ce8fa6c250e9392e0b1c5d 350 SUPERFAMILY SSF53756 10 338 6.28E-50 T 29-03-2018 GBCGDNIH2_RS02755 87e96479c7ce8fa6c250e9392e0b1c5d 350 Gene3D G3DSA:3.40.50.2000 161 336 1.7E-28 T 29-03-2018 GBCGDNIH2_RS02300 3d1fbdf7281cd011221713d26dc3793b 393 ProSitePatterns PS00099 Thiolases active site. 372 385 - T 29-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 GBCGDNIH2_RS02300 3d1fbdf7281cd011221713d26dc3793b 393 Pfam PF02803 Thiolase, C-terminal domain 270 390 1.9E-48 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 GBCGDNIH2_RS02300 3d1fbdf7281cd011221713d26dc3793b 393 Pfam PF00108 Thiolase, N-terminal domain 5 260 3.0E-97 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 GBCGDNIH2_RS02300 3d1fbdf7281cd011221713d26dc3793b 393 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 84 102 - T 29-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 GBCGDNIH2_RS02300 3d1fbdf7281cd011221713d26dc3793b 393 Gene3D G3DSA:3.40.47.10 1 263 2.3E-57 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 GBCGDNIH2_RS02300 3d1fbdf7281cd011221713d26dc3793b 393 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 389 2.7E-137 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 GBCGDNIH2_RS02300 3d1fbdf7281cd011221713d26dc3793b 393 ProSitePatterns PS00737 Thiolases signature 2. 337 353 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 GBCGDNIH2_RS02300 3d1fbdf7281cd011221713d26dc3793b 393 PIRSF PIRSF000429 1 392 2.5E-127 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 GBCGDNIH2_RS02300 3d1fbdf7281cd011221713d26dc3793b 393 SUPERFAMILY SSF53901 5 267 2.58E-84 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 GBCGDNIH2_RS02300 3d1fbdf7281cd011221713d26dc3793b 393 Gene3D G3DSA:3.40.47.10 264 388 8.6E-33 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 GBCGDNIH2_RS02300 3d1fbdf7281cd011221713d26dc3793b 393 SUPERFAMILY SSF53901 270 390 2.66E-43 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 GBCGDNIH2_RS02000 a3586a8233b91f73bb1ca5e1474c1792 244 SUPERFAMILY SSF53067 22 124 1.75E-10 T 29-03-2018 GBCGDNIH2_RS02000 a3586a8233b91f73bb1ca5e1474c1792 244 Gene3D G3DSA:3.30.420.40 19 151 1.3E-16 T 29-03-2018 GBCGDNIH2_RS02000 a3586a8233b91f73bb1ca5e1474c1792 244 Pfam PF00814 Glycoprotease family 60 150 8.4E-8 T 29-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 GBCGDNIH2_RS09120 55d7a8051ecbbf5c2fa9d7d69ed8d6ea 384 SUPERFAMILY SSF55729 183 348 1.32E-34 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase GBCGDNIH2_RS09120 55d7a8051ecbbf5c2fa9d7d69ed8d6ea 384 Pfam PF04339 Peptidogalycan biosysnthesis/recognition 17 381 2.3E-150 T 29-03-2018 IPR007434 Peptidogalycan biosysnthesis/recognition GBCGDNIH2_RS09120 55d7a8051ecbbf5c2fa9d7d69ed8d6ea 384 Gene3D G3DSA:3.40.630.30 190 351 9.8E-33 T 29-03-2018 GBCGDNIH2_RS09120 55d7a8051ecbbf5c2fa9d7d69ed8d6ea 384 Gene3D G3DSA:3.40.630.30 16 189 2.1E-11 T 29-03-2018 GBCGDNIH2_RS01960 cbd53d27770f430ce3f82e71f31ff56d 386 SUPERFAMILY SSF53383 28 384 7.85E-92 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase GBCGDNIH2_RS01960 cbd53d27770f430ce3f82e71f31ff56d 386 Gene3D G3DSA:3.90.1150.10 295 385 5.6E-14 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 GBCGDNIH2_RS01960 cbd53d27770f430ce3f82e71f31ff56d 386 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 234 247 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 GBCGDNIH2_RS01960 cbd53d27770f430ce3f82e71f31ff56d 386 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 166 190 7.4E-11 T 29-03-2018 GBCGDNIH2_RS01960 cbd53d27770f430ce3f82e71f31ff56d 386 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 202 225 7.4E-11 T 29-03-2018 GBCGDNIH2_RS01960 cbd53d27770f430ce3f82e71f31ff56d 386 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 120 141 7.4E-11 T 29-03-2018 GBCGDNIH2_RS01960 cbd53d27770f430ce3f82e71f31ff56d 386 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 98 118 7.4E-11 T 29-03-2018 GBCGDNIH2_RS01960 cbd53d27770f430ce3f82e71f31ff56d 386 Gene3D G3DSA:3.40.640.10 52 294 7.7E-55 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GBCGDNIH2_RS01960 cbd53d27770f430ce3f82e71f31ff56d 386 Pfam PF00155 Aminotransferase class I and II 37 382 2.6E-52 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 GBCGDNIH2_RS11455 809ac53dc2afce9a188a00814ad6f48b 431 SUPERFAMILY SSF53901 12 273 3.4E-73 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 GBCGDNIH2_RS11455 809ac53dc2afce9a188a00814ad6f48b 431 PIRSF PIRSF000447 9 431 4.3E-177 T 29-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 GBCGDNIH2_RS11455 809ac53dc2afce9a188a00814ad6f48b 431 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 12 266 1.1E-59 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal GBCGDNIH2_RS11455 809ac53dc2afce9a188a00814ad6f48b 431 SMART SM00825 Beta-ketoacyl synthase 14 431 4.1E-14 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain GBCGDNIH2_RS11455 809ac53dc2afce9a188a00814ad6f48b 431 SUPERFAMILY SSF53901 235 430 5.76E-68 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 GBCGDNIH2_RS11455 809ac53dc2afce9a188a00814ad6f48b 431 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 12 429 7.9E-188 T 29-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 GBCGDNIH2_RS11455 809ac53dc2afce9a188a00814ad6f48b 431 Gene3D G3DSA:3.40.47.10 282 431 6.2E-49 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 GBCGDNIH2_RS11455 809ac53dc2afce9a188a00814ad6f48b 431 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 274 388 5.9E-37 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal GBCGDNIH2_RS11455 809ac53dc2afce9a188a00814ad6f48b 431 Gene3D G3DSA:3.40.47.10 14 279 9.0E-81 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 GBCGDNIH2_RS11455 809ac53dc2afce9a188a00814ad6f48b 431 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 173 189 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site GBCGDNIH2_RS02160 ab8f94aeedb7fa32b5210ee1da6237d3 700 SUPERFAMILY SSF50249 333 417 1.01E-26 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold GBCGDNIH2_RS02160 ab8f94aeedb7fa32b5210ee1da6237d3 700 Gene3D G3DSA:3.40.50.10190 594 697 1.1E-20 T 29-03-2018 IPR001357 BRCT domain GBCGDNIH2_RS02160 ab8f94aeedb7fa32b5210ee1da6237d3 700 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 337 413 1.6E-34 T 29-03-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 GBCGDNIH2_RS02160 ab8f94aeedb7fa32b5210ee1da6237d3 700 Hamap MF_01588 DNA ligase [ligA]. 20 697 48.229 T 29-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 GBCGDNIH2_RS02160 ab8f94aeedb7fa32b5210ee1da6237d3 700 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 133 162 - T 29-03-2018 IPR018239 NAD-dependent DNA ligase, active site GBCGDNIH2_RS02160 ab8f94aeedb7fa32b5210ee1da6237d3 700 Pfam PF12826 Helix-hairpin-helix motif 528 600 8.5E-13 T 29-03-2018 GBCGDNIH2_RS02160 ab8f94aeedb7fa32b5210ee1da6237d3 700 Gene3D G3DSA:3.30.470.30 137 254 4.4E-50 T 29-03-2018 GBCGDNIH2_RS02160 ab8f94aeedb7fa32b5210ee1da6237d3 700 Gene3D G3DSA:2.40.50.140 338 406 1.6E-34 T 29-03-2018 GBCGDNIH2_RS02160 ab8f94aeedb7fa32b5210ee1da6237d3 700 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 30 693 5.4E-223 T 29-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 GBCGDNIH2_RS02160 ab8f94aeedb7fa32b5210ee1da6237d3 700 SUPERFAMILY SSF47781 422 605 2.07E-46 T 29-03-2018 IPR010994 RuvA domain 2-like GBCGDNIH2_RS02160 ab8f94aeedb7fa32b5210ee1da6237d3 700 SUPERFAMILY SSF56091 18 332 2.24E-112 T 29-03-2018 GBCGDNIH2_RS02160 ab8f94aeedb7fa32b5210ee1da6237d3 700 Gene3D G3DSA:1.10.287.610 12 84 7.7E-20 T 29-03-2018 GBCGDNIH2_RS02160 ab8f94aeedb7fa32b5210ee1da6237d3 700 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 21 334 1.2E-114 T 29-03-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 GBCGDNIH2_RS02160 ab8f94aeedb7fa32b5210ee1da6237d3 700 PIRSF PIRSF001604 15 698 2.7E-222 T 29-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 GBCGDNIH2_RS02160 ab8f94aeedb7fa32b5210ee1da6237d3 700 Gene3D G3DSA:1.10.150.20 521 593 2.8E-24 T 29-03-2018 GBCGDNIH2_RS02160 ab8f94aeedb7fa32b5210ee1da6237d3 700 Gene3D G3DSA:1.10.150.20 448 520 2.7E-21 T 29-03-2018 GBCGDNIH2_RS02160 ab8f94aeedb7fa32b5210ee1da6237d3 700 SMART SM00532 21 464 6.1E-236 T 29-03-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 GBCGDNIH2_RS02160 ab8f94aeedb7fa32b5210ee1da6237d3 700 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 423 450 6.2E-10 T 29-03-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 GBCGDNIH2_RS02160 ab8f94aeedb7fa32b5210ee1da6237d3 700 Gene3D G3DSA:3.30.1490.70 255 337 1.6E-24 T 29-03-2018 GBCGDNIH2_RS02160 ab8f94aeedb7fa32b5210ee1da6237d3 700 SMART SM00292 623 700 7.1E-12 T 29-03-2018 IPR001357 BRCT domain GBCGDNIH2_RS02160 ab8f94aeedb7fa32b5210ee1da6237d3 700 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 624 696 2.8E-14 T 29-03-2018 IPR001357 BRCT domain GBCGDNIH2_RS02160 ab8f94aeedb7fa32b5210ee1da6237d3 700 SUPERFAMILY SSF52113 623 696 1.68E-18 T 29-03-2018 IPR001357 BRCT domain GBCGDNIH2_RS04385 55d0fed57ba6721c202619b5cfd7adb7 325 Gene3D G3DSA:1.10.1040.10 187 324 2.9E-40 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 GBCGDNIH2_RS04385 55d0fed57ba6721c202619b5cfd7adb7 325 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 185 303 1.6E-19 T 29-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 GBCGDNIH2_RS04385 55d0fed57ba6721c202619b5cfd7adb7 325 Gene3D G3DSA:3.40.50.720 1 186 1.9E-35 T 29-03-2018 GBCGDNIH2_RS04385 55d0fed57ba6721c202619b5cfd7adb7 325 SUPERFAMILY SSF48179 183 309 3.81E-38 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 GBCGDNIH2_RS04385 55d0fed57ba6721c202619b5cfd7adb7 325 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 154 2.2E-42 T 29-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 GBCGDNIH2_RS04385 55d0fed57ba6721c202619b5cfd7adb7 325 SMART SM01350 185 324 7.0E-5 T 29-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 GBCGDNIH2_RS04385 55d0fed57ba6721c202619b5cfd7adb7 325 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 1 24 1.7E-19 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 GBCGDNIH2_RS04385 55d0fed57ba6721c202619b5cfd7adb7 325 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 174 202 1.7E-19 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 GBCGDNIH2_RS04385 55d0fed57ba6721c202619b5cfd7adb7 325 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 258 285 1.7E-19 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 GBCGDNIH2_RS04385 55d0fed57ba6721c202619b5cfd7adb7 325 TIGRFAM TIGR00872 gnd_rel: 6-phosphogluconate dehydrogenase (decarboxylating) 1 324 1.9E-122 T 29-03-2018 IPR004849 6-phosphogluconate dehydrogenase, YqeC-type GO:0055114 GBCGDNIH2_RS04385 55d0fed57ba6721c202619b5cfd7adb7 325 SUPERFAMILY SSF51735 1 160 1.75E-48 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS11755 d85e4292cb86aadfe290f149edfa50fc 317 Pfam PF01430 Hsp33 protein 24 308 7.0E-69 T 29-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 GBCGDNIH2_RS11755 d85e4292cb86aadfe290f149edfa50fc 317 SUPERFAMILY SSF118352 263 314 1.7E-12 T 29-03-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 GBCGDNIH2_RS11755 d85e4292cb86aadfe290f149edfa50fc 317 PIRSF PIRSF005261 14 317 2.0E-66 T 29-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 GBCGDNIH2_RS11755 d85e4292cb86aadfe290f149edfa50fc 317 SUPERFAMILY SSF64397 24 271 1.7E-55 T 29-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 GBCGDNIH2_RS11755 d85e4292cb86aadfe290f149edfa50fc 317 Gene3D G3DSA:3.90.1280.10 265 315 4.5E-14 T 29-03-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 GBCGDNIH2_RS11755 d85e4292cb86aadfe290f149edfa50fc 317 Gene3D G3DSA:3.55.30.10 23 264 1.6E-63 T 29-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 GBCGDNIH2_RS05795 0519914ef5f9fc991813c6a1d974d4f9 331 SUPERFAMILY SSF53955 27 328 9.14E-97 T 29-03-2018 IPR023346 Lysozyme-like domain GBCGDNIH2_RS05795 0519914ef5f9fc991813c6a1d974d4f9 331 Gene3D G3DSA:1.10.530.10 210 331 1.4E-33 T 29-03-2018 GBCGDNIH2_RS05795 0519914ef5f9fc991813c6a1d974d4f9 331 Gene3D G3DSA:1.10.8.350 100 204 3.5E-33 T 29-03-2018 GBCGDNIH2_RS05795 0519914ef5f9fc991813c6a1d974d4f9 331 TIGRFAM TIGR02283 MltB_2: lytic murein transglycosylase 35 329 8.8E-106 T 29-03-2018 IPR011970 Lytic murein transglycosylase GBCGDNIH2_RS05795 0519914ef5f9fc991813c6a1d974d4f9 331 Pfam PF13406 Transglycosylase SLT domain 36 327 1.7E-107 T 29-03-2018 IPR031304 Transglycosylase SLT domain 2 GBCGDNIH2_RS01325 880277eca21525cc228c5c48277c7d83 686 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 48 411 1.7E-122 T 29-03-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 GBCGDNIH2_RS01325 880277eca21525cc228c5c48277c7d83 686 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 284 426 2.4E-52 T 29-03-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 GBCGDNIH2_RS01325 880277eca21525cc228c5c48277c7d83 686 Pfam PF12362 DNA polymerase III gamma and tau subunits C terminal 495 607 4.3E-35 T 29-03-2018 IPR022107 DNA polymerase III, subunit gamma/ tau, C-terminal GBCGDNIH2_RS01325 880277eca21525cc228c5c48277c7d83 686 Gene3D G3DSA:1.20.272.10 295 416 1.5E-15 T 29-03-2018 GBCGDNIH2_RS01325 880277eca21525cc228c5c48277c7d83 686 Pfam PF13177 DNA polymerase III, delta subunit 65 228 8.4E-39 T 29-03-2018 GBCGDNIH2_RS01325 880277eca21525cc228c5c48277c7d83 686 SUPERFAMILY SSF48019 295 421 2.89E-29 T 29-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 GBCGDNIH2_RS01325 880277eca21525cc228c5c48277c7d83 686 SMART SM00382 82 229 1.6E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS01325 880277eca21525cc228c5c48277c7d83 686 Gene3D G3DSA:3.40.50.300 40 216 2.0E-41 T 29-03-2018 GBCGDNIH2_RS01325 880277eca21525cc228c5c48277c7d83 686 SUPERFAMILY SSF52540 79 271 4.13E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS01325 880277eca21525cc228c5c48277c7d83 686 Gene3D G3DSA:1.10.8.60 217 294 3.8E-18 T 29-03-2018 GBCGDNIH2_RS07250 0d5344bfbf10dd415706f2723d81d995 209 Pfam PF02798 Glutathione S-transferase, N-terminal domain 5 77 6.8E-11 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 GBCGDNIH2_RS07250 0d5344bfbf10dd415706f2723d81d995 209 SUPERFAMILY SSF52833 5 94 1.82E-18 T 29-03-2018 IPR012336 Thioredoxin-like fold GBCGDNIH2_RS07250 0d5344bfbf10dd415706f2723d81d995 209 Gene3D G3DSA:1.20.1050.10 98 209 2.6E-17 T 29-03-2018 GBCGDNIH2_RS07250 0d5344bfbf10dd415706f2723d81d995 209 SUPERFAMILY SSF47616 82 208 5.01E-20 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like GBCGDNIH2_RS07250 0d5344bfbf10dd415706f2723d81d995 209 Gene3D G3DSA:3.40.30.10 2 97 1.2E-25 T 29-03-2018 GBCGDNIH2_RS07250 0d5344bfbf10dd415706f2723d81d995 209 Pfam PF00043 Glutathione S-transferase, C-terminal domain 130 178 2.9E-5 T 29-03-2018 IPR004046 Glutathione S-transferase, C-terminal GBCGDNIH2_RS03285 ff4c229957ae9527cdafde519245d72d 495 Gene3D G3DSA:3.50.50.60 405 489 0.094 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS03285 ff4c229957ae9527cdafde519245d72d 495 Gene3D G3DSA:3.50.50.60 200 399 5.6E-6 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS03285 ff4c229957ae9527cdafde519245d72d 495 SUPERFAMILY SSF51905 218 264 9.36E-6 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS03285 ff4c229957ae9527cdafde519245d72d 495 SUPERFAMILY SSF51905 335 477 9.36E-6 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS03285 ff4c229957ae9527cdafde519245d72d 495 SUPERFAMILY SSF51905 22 257 1.81E-13 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS03285 ff4c229957ae9527cdafde519245d72d 495 Pfam PF13454 FAD-NAD(P)-binding 24 183 8.9E-32 T 29-03-2018 GBCGDNIH2_RS03285 ff4c229957ae9527cdafde519245d72d 495 Gene3D G3DSA:3.50.50.60 21 199 1.4E-10 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS03075 91f22a6659ae7d3476ce71c7fc1e40de 355 SUPERFAMILY SSF51412 32 350 1.04E-47 T 29-03-2018 GBCGDNIH2_RS03075 91f22a6659ae7d3476ce71c7fc1e40de 355 Pfam PF03060 Nitronate monooxygenase 33 344 1.5E-47 T 29-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 GBCGDNIH2_RS03075 91f22a6659ae7d3476ce71c7fc1e40de 355 Gene3D G3DSA:3.20.20.70 20 352 2.8E-47 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS07560 3e2d1867edae4edff2b9d4e1f4104424 379 Gene3D G3DSA:3.90.1170.20 7 118 2.3E-17 T 29-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 GBCGDNIH2_RS07560 3e2d1867edae4edff2b9d4e1f4104424 379 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 55 108 2.2E-4 T 29-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 GBCGDNIH2_RS07560 3e2d1867edae4edff2b9d4e1f4104424 379 Gene3D G3DSA:3.20.20.70 119 347 1.0E-30 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS07560 3e2d1867edae4edff2b9d4e1f4104424 379 SUPERFAMILY SSF51690 117 250 7.98E-33 T 29-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 GBCGDNIH2_RS07560 3e2d1867edae4edff2b9d4e1f4104424 379 SUPERFAMILY SSF51690 287 371 7.98E-33 T 29-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 GBCGDNIH2_RS07560 3e2d1867edae4edff2b9d4e1f4104424 379 SUPERFAMILY SSF54675 28 108 2.22E-6 T 29-03-2018 GBCGDNIH2_RS03425 86192729e83f68de2e83e82926abb129 1044 Gene3D G3DSA:3.30.70.1320 766 844 5.9E-11 T 29-03-2018 GBCGDNIH2_RS03425 86192729e83f68de2e83e82926abb129 1044 Gene3D G3DSA:3.30.70.1430 566 667 2.8E-21 T 29-03-2018 GBCGDNIH2_RS03425 86192729e83f68de2e83e82926abb129 1044 Pfam PF00873 AcrB/AcrD/AcrF family 2 1025 0.0 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS03425 86192729e83f68de2e83e82926abb129 1044 SUPERFAMILY SSF82693 39 133 1.28E-22 T 29-03-2018 GBCGDNIH2_RS03425 86192729e83f68de2e83e82926abb129 1044 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 3 1030 0.0 T 29-03-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 GBCGDNIH2_RS03425 86192729e83f68de2e83e82926abb129 1044 Gene3D G3DSA:1.20.1640.10 845 1038 9.7E-33 T 29-03-2018 GBCGDNIH2_RS03425 86192729e83f68de2e83e82926abb129 1044 SUPERFAMILY SSF82693 564 670 1.31E-29 T 29-03-2018 GBCGDNIH2_RS03425 86192729e83f68de2e83e82926abb129 1044 SUPERFAMILY SSF82866 298 501 8.5E-50 T 29-03-2018 GBCGDNIH2_RS03425 86192729e83f68de2e83e82926abb129 1044 Gene3D G3DSA:1.20.1640.10 275 503 1.5E-48 T 29-03-2018 GBCGDNIH2_RS03425 86192729e83f68de2e83e82926abb129 1044 SUPERFAMILY SSF82693 139 183 9.42E-23 T 29-03-2018 GBCGDNIH2_RS03425 86192729e83f68de2e83e82926abb129 1044 SUPERFAMILY SSF82693 276 332 9.42E-23 T 29-03-2018 GBCGDNIH2_RS03425 86192729e83f68de2e83e82926abb129 1044 Gene3D G3DSA:3.30.70.1440 671 765 1.8E-17 T 29-03-2018 GBCGDNIH2_RS03425 86192729e83f68de2e83e82926abb129 1044 PRINTS PR00702 Acriflavin resistance protein family signature 620 634 7.6E-88 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS03425 86192729e83f68de2e83e82926abb129 1044 PRINTS PR00702 Acriflavin resistance protein family signature 473 496 7.6E-88 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS03425 86192729e83f68de2e83e82926abb129 1044 PRINTS PR00702 Acriflavin resistance protein family signature 338 361 7.6E-88 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS03425 86192729e83f68de2e83e82926abb129 1044 PRINTS PR00702 Acriflavin resistance protein family signature 393 417 7.6E-88 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS03425 86192729e83f68de2e83e82926abb129 1044 PRINTS PR00702 Acriflavin resistance protein family signature 448 471 7.6E-88 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS03425 86192729e83f68de2e83e82926abb129 1044 PRINTS PR00702 Acriflavin resistance protein family signature 37 55 7.6E-88 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS03425 86192729e83f68de2e83e82926abb129 1044 PRINTS PR00702 Acriflavin resistance protein family signature 9 33 7.6E-88 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS03425 86192729e83f68de2e83e82926abb129 1044 PRINTS PR00702 Acriflavin resistance protein family signature 551 568 7.6E-88 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS03425 86192729e83f68de2e83e82926abb129 1044 PRINTS PR00702 Acriflavin resistance protein family signature 365 386 7.6E-88 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS03425 86192729e83f68de2e83e82926abb129 1044 SUPERFAMILY SSF82866 805 1028 7.72E-41 T 29-03-2018 GBCGDNIH2_RS03425 86192729e83f68de2e83e82926abb129 1044 Gene3D G3DSA:3.30.2090.10 182 274 3.7E-17 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains GBCGDNIH2_RS03425 86192729e83f68de2e83e82926abb129 1044 Gene3D G3DSA:3.30.70.1430 39 141 3.5E-22 T 29-03-2018 GBCGDNIH2_RS03425 86192729e83f68de2e83e82926abb129 1044 SUPERFAMILY SSF82714 721 806 1.44E-21 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains GBCGDNIH2_RS03425 86192729e83f68de2e83e82926abb129 1044 SUPERFAMILY SSF82714 184 273 7.32E-21 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains GBCGDNIH2_RS09310 fe8ddff6db7d7ef8f33524275e4f24c1 224 Gene3D G3DSA:1.10.10.60 11 52 1.6E-10 T 29-03-2018 GBCGDNIH2_RS09310 fe8ddff6db7d7ef8f33524275e4f24c1 224 Pfam PF00440 Bacterial regulatory proteins, tetR family 32 78 7.0E-14 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GBCGDNIH2_RS09310 fe8ddff6db7d7ef8f33524275e4f24c1 224 SUPERFAMILY SSF46689 24 86 9.75E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 GBCGDNIH2_RS09310 fe8ddff6db7d7ef8f33524275e4f24c1 224 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 45 2.9E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GBCGDNIH2_RS09310 fe8ddff6db7d7ef8f33524275e4f24c1 224 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 53 76 2.9E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GBCGDNIH2_RS09310 fe8ddff6db7d7ef8f33524275e4f24c1 224 Gene3D G3DSA:1.10.357.10 77 217 7.4E-14 T 29-03-2018 GBCGDNIH2_RS09310 fe8ddff6db7d7ef8f33524275e4f24c1 224 Gene3D G3DSA:1.10.260.40 53 76 1.4E-8 T 29-03-2018 GBCGDNIH2_RS06300 496b3ce60d61e75b539a9ac5b1a5dc7c 299 SUPERFAMILY SSF46785 4 82 3.23E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS06300 496b3ce60d61e75b539a9ac5b1a5dc7c 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 1.7E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS06300 496b3ce60d61e75b539a9ac5b1a5dc7c 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 1.7E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS06300 496b3ce60d61e75b539a9ac5b1a5dc7c 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 1.7E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS06300 496b3ce60d61e75b539a9ac5b1a5dc7c 299 SUPERFAMILY SSF53850 97 295 1.1E-31 T 29-03-2018 GBCGDNIH2_RS06300 496b3ce60d61e75b539a9ac5b1a5dc7c 299 Gene3D G3DSA:3.40.190.10 95 178 6.7E-17 T 29-03-2018 GBCGDNIH2_RS06300 496b3ce60d61e75b539a9ac5b1a5dc7c 299 Gene3D G3DSA:3.40.190.10 179 261 7.4E-20 T 29-03-2018 GBCGDNIH2_RS06300 496b3ce60d61e75b539a9ac5b1a5dc7c 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 67 7.8E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS06300 496b3ce60d61e75b539a9ac5b1a5dc7c 299 Gene3D G3DSA:1.10.10.10 6 87 3.6E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS06300 496b3ce60d61e75b539a9ac5b1a5dc7c 299 Pfam PF03466 LysR substrate binding domain 96 291 9.4E-31 T 29-03-2018 IPR005119 LysR, substrate-binding GBCGDNIH2_RS11705 dc7ff948c5d65b32779649cda36dd415 300 SUPERFAMILY SSF81464 41 137 7.03E-29 T 29-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS11705 dc7ff948c5d65b32779649cda36dd415 300 Gene3D G3DSA:2.60.40.420 137 297 4.9E-55 T 29-03-2018 IPR008972 Cupredoxin GBCGDNIH2_RS11705 dc7ff948c5d65b32779649cda36dd415 300 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 208 256 - T 29-03-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS11705 dc7ff948c5d65b32779649cda36dd415 300 Gene3D G3DSA:1.10.287.90 46 136 6.3E-30 T 29-03-2018 GBCGDNIH2_RS11705 dc7ff948c5d65b32779649cda36dd415 300 PRINTS PR01166 Cytochrome c oxidase subunit II signature 245 262 6.4E-47 T 29-03-2018 GBCGDNIH2_RS11705 dc7ff948c5d65b32779649cda36dd415 300 PRINTS PR01166 Cytochrome c oxidase subunit II signature 140 159 6.4E-47 T 29-03-2018 GBCGDNIH2_RS11705 dc7ff948c5d65b32779649cda36dd415 300 PRINTS PR01166 Cytochrome c oxidase subunit II signature 207 227 6.4E-47 T 29-03-2018 GBCGDNIH2_RS11705 dc7ff948c5d65b32779649cda36dd415 300 PRINTS PR01166 Cytochrome c oxidase subunit II signature 106 118 6.4E-47 T 29-03-2018 GBCGDNIH2_RS11705 dc7ff948c5d65b32779649cda36dd415 300 PRINTS PR01166 Cytochrome c oxidase subunit II signature 183 204 6.4E-47 T 29-03-2018 GBCGDNIH2_RS11705 dc7ff948c5d65b32779649cda36dd415 300 PRINTS PR01166 Cytochrome c oxidase subunit II signature 227 244 6.4E-47 T 29-03-2018 GBCGDNIH2_RS11705 dc7ff948c5d65b32779649cda36dd415 300 PRINTS PR01166 Cytochrome c oxidase subunit II signature 118 138 6.4E-47 T 29-03-2018 GBCGDNIH2_RS11705 dc7ff948c5d65b32779649cda36dd415 300 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 145 263 4.8E-42 T 29-03-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS11705 dc7ff948c5d65b32779649cda36dd415 300 SUPERFAMILY SSF49503 141 278 2.87E-54 T 29-03-2018 IPR008972 Cupredoxin GBCGDNIH2_RS11705 dc7ff948c5d65b32779649cda36dd415 300 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 59 273 4.7E-56 T 29-03-2018 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS11705 dc7ff948c5d65b32779649cda36dd415 300 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 45 132 5.3E-24 T 29-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS11295 7097563f78401ef4ceaa6787953273d7 968 SUPERFAMILY SSF52540 895 920 3.31E-14 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS11295 7097563f78401ef4ceaa6787953273d7 968 SUPERFAMILY SSF52540 181 317 3.31E-14 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS11295 7097563f78401ef4ceaa6787953273d7 968 SUPERFAMILY SSF52540 399 455 3.31E-14 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS11295 7097563f78401ef4ceaa6787953273d7 968 SUPERFAMILY SSF52540 858 868 3.31E-14 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS11295 7097563f78401ef4ceaa6787953273d7 968 SMART SM00491 799 925 4.7E-7 T 29-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 GBCGDNIH2_RS11295 7097563f78401ef4ceaa6787953273d7 968 Gene3D G3DSA:3.40.50.300 217 734 8.6E-21 T 29-03-2018 GBCGDNIH2_RS11295 7097563f78401ef4ceaa6787953273d7 968 Pfam PF13307 Helicase C-terminal domain 784 924 4.9E-16 T 29-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 GBCGDNIH2_RS11295 7097563f78401ef4ceaa6787953273d7 968 Gene3D G3DSA:3.40.50.300 763 948 8.5E-7 T 29-03-2018 GBCGDNIH2_RS01130 ee418bd738ef5e90066bab8548c11014 1318 SUPERFAMILY SSF56801 14 537 4.71E-148 T 29-03-2018 GBCGDNIH2_RS01130 ee418bd738ef5e90066bab8548c11014 1318 Gene3D G3DSA:1.10.1200.10 533 601 3.8E-12 T 29-03-2018 GBCGDNIH2_RS01130 ee418bd738ef5e90066bab8548c11014 1318 Gene3D G3DSA:3.40.50.980 10 167 4.7E-41 T 29-03-2018 GBCGDNIH2_RS01130 ee418bd738ef5e90066bab8548c11014 1318 SUPERFAMILY SSF51161 728 841 4.99E-16 T 29-03-2018 IPR011004 Trimeric LpxA-like GBCGDNIH2_RS01130 ee418bd738ef5e90066bab8548c11014 1318 TIGRFAM TIGR02353 NRPS_term_dom: non-ribosomal peptide synthetase terminal domain of unknown function 623 1314 6.8E-206 T 29-03-2018 IPR012728 Non-ribosomal peptide synthetase, C-terminal GBCGDNIH2_RS01130 ee418bd738ef5e90066bab8548c11014 1318 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 40 440 2.6E-117 T 29-03-2018 IPR010071 Amino acid adenylation domain GBCGDNIH2_RS01130 ee418bd738ef5e90066bab8548c11014 1318 Pfam PF13193 AMP-binding enzyme C-terminal domain 424 499 6.6E-8 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain GBCGDNIH2_RS01130 ee418bd738ef5e90066bab8548c11014 1318 ProSitePatterns PS00012 Phosphopantetheine attachment site. 552 567 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site GBCGDNIH2_RS01130 ee418bd738ef5e90066bab8548c11014 1318 Gene3D G3DSA:2.160.10.10 732 849 6.8E-14 T 29-03-2018 GBCGDNIH2_RS01130 ee418bd738ef5e90066bab8548c11014 1318 Pfam PF00550 Phosphopantetheine attachment site 546 592 3.8E-5 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain GBCGDNIH2_RS01130 ee418bd738ef5e90066bab8548c11014 1318 Gene3D G3DSA:3.30.300.30 411 532 4.0E-33 T 29-03-2018 GBCGDNIH2_RS01130 ee418bd738ef5e90066bab8548c11014 1318 SUPERFAMILY SSF51161 1194 1316 1.39E-12 T 29-03-2018 IPR011004 Trimeric LpxA-like GBCGDNIH2_RS01130 ee418bd738ef5e90066bab8548c11014 1318 SUPERFAMILY SSF47336 521 616 8.51E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain GBCGDNIH2_RS01130 ee418bd738ef5e90066bab8548c11014 1318 SUPERFAMILY SSF51161 965 1079 1.52E-13 T 29-03-2018 IPR011004 Trimeric LpxA-like GBCGDNIH2_RS01130 ee418bd738ef5e90066bab8548c11014 1318 Pfam PF00501 AMP-binding enzyme 20 415 2.1E-89 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 GBCGDNIH2_RS01130 ee418bd738ef5e90066bab8548c11014 1318 Gene3D G3DSA:3.40.50.980 168 311 4.5E-34 T 29-03-2018 GBCGDNIH2_RS01130 ee418bd738ef5e90066bab8548c11014 1318 Gene3D G3DSA:2.30.38.10 312 408 1.2E-21 T 29-03-2018 GBCGDNIH2_RS01130 ee418bd738ef5e90066bab8548c11014 1318 Gene3D G3DSA:2.160.10.10 1208 1318 1.4E-10 T 29-03-2018 GBCGDNIH2_RS01130 ee418bd738ef5e90066bab8548c11014 1318 Gene3D G3DSA:2.160.10.10 954 1066 3.0E-12 T 29-03-2018 GBCGDNIH2_RS00745 fbcb15036f21227d39e2c51f8c5f9928 372 Gene3D G3DSA:2.40.10.10 45 173 2.3E-34 T 29-03-2018 GBCGDNIH2_RS00745 fbcb15036f21227d39e2c51f8c5f9928 372 PRINTS PR00834 HtrA/DegQ protease family signature 137 157 2.9E-51 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 GBCGDNIH2_RS00745 fbcb15036f21227d39e2c51f8c5f9928 372 PRINTS PR00834 HtrA/DegQ protease family signature 312 324 2.9E-51 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 GBCGDNIH2_RS00745 fbcb15036f21227d39e2c51f8c5f9928 372 PRINTS PR00834 HtrA/DegQ protease family signature 178 202 2.9E-51 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 GBCGDNIH2_RS00745 fbcb15036f21227d39e2c51f8c5f9928 372 PRINTS PR00834 HtrA/DegQ protease family signature 212 229 2.9E-51 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 GBCGDNIH2_RS00745 fbcb15036f21227d39e2c51f8c5f9928 372 PRINTS PR00834 HtrA/DegQ protease family signature 234 251 2.9E-51 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 GBCGDNIH2_RS00745 fbcb15036f21227d39e2c51f8c5f9928 372 PRINTS PR00834 HtrA/DegQ protease family signature 116 128 2.9E-51 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 GBCGDNIH2_RS00745 fbcb15036f21227d39e2c51f8c5f9928 372 SMART SM00228 280 354 2.0E-14 T 29-03-2018 IPR001478 PDZ domain GO:0005515 GBCGDNIH2_RS00745 fbcb15036f21227d39e2c51f8c5f9928 372 Pfam PF13365 Trypsin-like peptidase domain 107 241 4.8E-31 T 29-03-2018 GBCGDNIH2_RS00745 fbcb15036f21227d39e2c51f8c5f9928 372 SUPERFAMILY SSF50156 249 367 6.44E-23 T 29-03-2018 IPR001478 PDZ domain GO:0005515 GBCGDNIH2_RS00745 fbcb15036f21227d39e2c51f8c5f9928 372 Gene3D G3DSA:2.30.42.10 278 372 1.9E-20 T 29-03-2018 GBCGDNIH2_RS00745 fbcb15036f21227d39e2c51f8c5f9928 372 SUPERFAMILY SSF50494 48 276 1.46E-59 T 29-03-2018 IPR009003 Peptidase S1, PA clan GBCGDNIH2_RS00745 fbcb15036f21227d39e2c51f8c5f9928 372 Gene3D G3DSA:2.40.10.10 174 274 3.6E-34 T 29-03-2018 GBCGDNIH2_RS00745 fbcb15036f21227d39e2c51f8c5f9928 372 Pfam PF13180 PDZ domain 280 363 2.8E-18 T 29-03-2018 IPR001478 PDZ domain GO:0005515 GBCGDNIH2_RS02055 706c7576cb7cf6d28ce6843b90301f8c 93 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 17 24 - T 29-03-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site GBCGDNIH2_RS02055 706c7576cb7cf6d28ce6843b90301f8c 93 Gene3D G3DSA:3.30.1340.10 2 86 2.8E-29 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like GBCGDNIH2_RS02055 706c7576cb7cf6d28ce6843b90301f8c 93 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 43 58 - T 29-03-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site GBCGDNIH2_RS02055 706c7576cb7cf6d28ce6843b90301f8c 93 PRINTS PR00107 Phosphocarrier protein signature 57 74 1.4E-13 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like GBCGDNIH2_RS02055 706c7576cb7cf6d28ce6843b90301f8c 93 PRINTS PR00107 Phosphocarrier protein signature 17 33 1.4E-13 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like GBCGDNIH2_RS02055 706c7576cb7cf6d28ce6843b90301f8c 93 PRINTS PR00107 Phosphocarrier protein signature 42 57 1.4E-13 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like GBCGDNIH2_RS02055 706c7576cb7cf6d28ce6843b90301f8c 93 SUPERFAMILY SSF55594 7 91 1.3E-27 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like GBCGDNIH2_RS02055 706c7576cb7cf6d28ce6843b90301f8c 93 Pfam PF00381 PTS HPr component phosphorylation site 7 86 1.1E-25 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like GBCGDNIH2_RS02055 706c7576cb7cf6d28ce6843b90301f8c 93 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 6 86 1.8E-27 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like GBCGDNIH2_RS00265 43ffde1432676df2ae46153541aa5310 298 SMART SM00881 4 100 3.4E-29 T 29-03-2018 IPR003781 CoA-binding GO:0048037 GBCGDNIH2_RS00265 43ffde1432676df2ae46153541aa5310 298 PRINTS PR01798 Succinyl-CoA synthase signature 181 199 6.5E-30 T 29-03-2018 GBCGDNIH2_RS00265 43ffde1432676df2ae46153541aa5310 298 PRINTS PR01798 Succinyl-CoA synthase signature 244 261 6.5E-30 T 29-03-2018 GBCGDNIH2_RS00265 43ffde1432676df2ae46153541aa5310 298 PRINTS PR01798 Succinyl-CoA synthase signature 212 225 6.5E-30 T 29-03-2018 GBCGDNIH2_RS00265 43ffde1432676df2ae46153541aa5310 298 PRINTS PR01798 Succinyl-CoA synthase signature 82 99 6.5E-30 T 29-03-2018 GBCGDNIH2_RS00265 43ffde1432676df2ae46153541aa5310 298 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 3 292 8.6E-125 T 29-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 GBCGDNIH2_RS00265 43ffde1432676df2ae46153541aa5310 298 PIRSF PIRSF001553 1 295 9.2E-124 T 29-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 GBCGDNIH2_RS00265 43ffde1432676df2ae46153541aa5310 298 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 240 253 - T 29-03-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site GBCGDNIH2_RS00265 43ffde1432676df2ae46153541aa5310 298 SUPERFAMILY SSF52210 127 293 7.46E-51 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 GBCGDNIH2_RS00265 43ffde1432676df2ae46153541aa5310 298 Pfam PF00549 CoA-ligase 155 270 5.1E-14 T 29-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 GBCGDNIH2_RS00265 43ffde1432676df2ae46153541aa5310 298 SUPERFAMILY SSF51735 1 126 4.33E-36 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS00265 43ffde1432676df2ae46153541aa5310 298 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 156 185 - T 29-03-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site GBCGDNIH2_RS00265 43ffde1432676df2ae46153541aa5310 298 Pfam PF02629 CoA binding domain 6 99 6.2E-26 T 29-03-2018 IPR003781 CoA-binding GO:0048037 GBCGDNIH2_RS00265 43ffde1432676df2ae46153541aa5310 298 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 292 40.352 T 29-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 GBCGDNIH2_RS00265 43ffde1432676df2ae46153541aa5310 298 Gene3D G3DSA:3.40.50.720 1 123 4.1E-41 T 29-03-2018 GBCGDNIH2_RS00265 43ffde1432676df2ae46153541aa5310 298 Gene3D G3DSA:3.40.50.261 124 298 2.9E-52 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 GBCGDNIH2_RS10095 43df68a1652967ec5a46385f8397d1a0 947 Pfam PF00384 Molybdopterin oxidoreductase 298 727 2.9E-75 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS10095 43df68a1652967ec5a46385f8397d1a0 947 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 242 289 3.7E-15 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS10095 43df68a1652967ec5a46385f8397d1a0 947 Gene3D G3DSA:3.40.228.10 401 481 4.5E-20 T 29-03-2018 GBCGDNIH2_RS10095 43df68a1652967ec5a46385f8397d1a0 947 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 101 140 1.6E-17 T 29-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS10095 43df68a1652967ec5a46385f8397d1a0 947 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 243 918 1.6E-285 T 29-03-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.2.1.2|KEGG: 00680+1.2.1.2|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696 GBCGDNIH2_RS10095 43df68a1652967ec5a46385f8397d1a0 947 Gene3D G3DSA:2.20.25.90 243 293 4.1E-13 T 29-03-2018 GBCGDNIH2_RS10095 43df68a1652967ec5a46385f8397d1a0 947 Pfam PF01568 Molydopterin dinucleotide binding domain 810 914 6.3E-27 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 GBCGDNIH2_RS10095 43df68a1652967ec5a46385f8397d1a0 947 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 211 222 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site GBCGDNIH2_RS10095 43df68a1652967ec5a46385f8397d1a0 947 Gene3D G3DSA:3.10.20.30 15 131 3.8E-16 T 29-03-2018 IPR012675 Beta-grasp domain GBCGDNIH2_RS10095 43df68a1652967ec5a46385f8397d1a0 947 Gene3D G3DSA:2.40.40.20 791 941 4.2E-34 T 29-03-2018 GBCGDNIH2_RS10095 43df68a1652967ec5a46385f8397d1a0 947 SMART SM00929 101 141 3.1E-20 T 29-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS10095 43df68a1652967ec5a46385f8397d1a0 947 PIRSF PIRSF036643 15 947 0.0 T 29-03-2018 GBCGDNIH2_RS10095 43df68a1652967ec5a46385f8397d1a0 947 SMART SM00926 238 292 5.6E-13 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS10095 43df68a1652967ec5a46385f8397d1a0 947 Pfam PF12838 4Fe-4S dicluster domain 166 224 2.4E-6 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain GBCGDNIH2_RS10095 43df68a1652967ec5a46385f8397d1a0 947 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 18 94 2.1E-25 T 29-03-2018 GBCGDNIH2_RS10095 43df68a1652967ec5a46385f8397d1a0 947 Gene3D G3DSA:3.40.50.740 295 400 1.2E-21 T 29-03-2018 GBCGDNIH2_RS10095 43df68a1652967ec5a46385f8397d1a0 947 Gene3D G3DSA:3.30.70.20 132 176 4.2E-4 T 29-03-2018 GBCGDNIH2_RS10095 43df68a1652967ec5a46385f8397d1a0 947 Gene3D G3DSA:3.30.70.20 213 242 0.033 T 29-03-2018 GBCGDNIH2_RS10095 43df68a1652967ec5a46385f8397d1a0 947 Gene3D G3DSA:3.30.70.20 177 212 3.1E-9 T 29-03-2018 GBCGDNIH2_RS10095 43df68a1652967ec5a46385f8397d1a0 947 SUPERFAMILY SSF50692 778 920 6.56E-39 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain GBCGDNIH2_RS10095 43df68a1652967ec5a46385f8397d1a0 947 SUPERFAMILY SSF54292 20 92 9.27E-20 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 GBCGDNIH2_RS10095 43df68a1652967ec5a46385f8397d1a0 947 Gene3D G3DSA:3.40.50.740 482 778 3.1E-80 T 29-03-2018 GBCGDNIH2_RS10095 43df68a1652967ec5a46385f8397d1a0 947 SUPERFAMILY SSF54862 93 233 2.09E-38 T 29-03-2018 GBCGDNIH2_RS10095 43df68a1652967ec5a46385f8397d1a0 947 SUPERFAMILY SSF53706 241 764 4.71E-190 T 29-03-2018 GBCGDNIH2_RS07010 629c40a2dd83f74692806739eb996add 810 SUPERFAMILY SSF52540 320 594 6.46E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS07010 629c40a2dd83f74692806739eb996add 810 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 365 384 3.8E-55 T 29-03-2018 GBCGDNIH2_RS07010 629c40a2dd83f74692806739eb996add 810 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 603 619 3.8E-55 T 29-03-2018 GBCGDNIH2_RS07010 629c40a2dd83f74692806739eb996add 810 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 711 730 3.8E-55 T 29-03-2018 GBCGDNIH2_RS07010 629c40a2dd83f74692806739eb996add 810 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 734 752 3.8E-55 T 29-03-2018 GBCGDNIH2_RS07010 629c40a2dd83f74692806739eb996add 810 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 681 700 3.8E-55 T 29-03-2018 GBCGDNIH2_RS07010 629c40a2dd83f74692806739eb996add 810 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 684 692 - T 29-03-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 GBCGDNIH2_RS07010 629c40a2dd83f74692806739eb996add 810 PIRSF PIRSF001174 5 783 0.0 T 29-03-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 GBCGDNIH2_RS07010 629c40a2dd83f74692806739eb996add 810 Hamap MF_01973 Lon protease [lon]. 20 780 72.951 T 29-03-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 GBCGDNIH2_RS07010 629c40a2dd83f74692806739eb996add 810 SUPERFAMILY SSF54211 603 778 3.6E-58 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold GBCGDNIH2_RS07010 629c40a2dd83f74692806739eb996add 810 Gene3D G3DSA:2.30.130.40 3 127 1.2E-31 T 29-03-2018 GBCGDNIH2_RS07010 629c40a2dd83f74692806739eb996add 810 SMART SM00382 357 503 3.4E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS07010 629c40a2dd83f74692806739eb996add 810 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 578 780 9.7E-98 T 29-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 GBCGDNIH2_RS07010 629c40a2dd83f74692806739eb996add 810 SUPERFAMILY SSF88697 20 210 1.94E-51 T 29-03-2018 IPR015947 PUA-like domain GBCGDNIH2_RS07010 629c40a2dd83f74692806739eb996add 810 SMART SM00464 19 211 2.5E-79 T 29-03-2018 IPR003111 Lon, substrate-binding domain GBCGDNIH2_RS07010 629c40a2dd83f74692806739eb996add 810 TIGRFAM TIGR00763 lon: endopeptidase La 21 778 6.5E-304 T 29-03-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 GBCGDNIH2_RS07010 629c40a2dd83f74692806739eb996add 810 Gene3D G3DSA:1.10.8.60 500 592 6.6E-31 T 29-03-2018 GBCGDNIH2_RS07010 629c40a2dd83f74692806739eb996add 810 Gene3D G3DSA:3.40.50.300 322 499 8.2E-32 T 29-03-2018 GBCGDNIH2_RS07010 629c40a2dd83f74692806739eb996add 810 Gene3D G3DSA:1.10.4060.10 131 220 2.8E-30 T 29-03-2018 GBCGDNIH2_RS07010 629c40a2dd83f74692806739eb996add 810 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 20 210 4.2E-44 T 29-03-2018 IPR003111 Lon, substrate-binding domain GBCGDNIH2_RS07010 629c40a2dd83f74692806739eb996add 810 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 361 496 2.2E-19 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 GBCGDNIH2_RS07010 629c40a2dd83f74692806739eb996add 810 Gene3D G3DSA:3.30.230.10 593 780 4.6E-69 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup GBCGDNIH2_RS08600 85602fca8f3e5f68cc3ba874ee857783 406 SUPERFAMILY SSF81891 141 398 3.01E-37 T 29-03-2018 GBCGDNIH2_RS08600 85602fca8f3e5f68cc3ba874ee857783 406 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 181 233 2.3E-11 T 29-03-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 GBCGDNIH2_RS08600 85602fca8f3e5f68cc3ba874ee857783 406 Gene3D G3DSA:3.30.460.10 9 139 2.0E-39 T 29-03-2018 GBCGDNIH2_RS08600 85602fca8f3e5f68cc3ba874ee857783 406 SUPERFAMILY SSF81301 12 139 9.81E-38 T 29-03-2018 GBCGDNIH2_RS08600 85602fca8f3e5f68cc3ba874ee857783 406 Pfam PF01743 Poly A polymerase head domain 24 143 1.1E-27 T 29-03-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 GBCGDNIH2_RS08600 85602fca8f3e5f68cc3ba874ee857783 406 Gene3D G3DSA:1.10.3090.10 140 399 2.3E-30 T 29-03-2018 GBCGDNIH2_RS07540 d0a77a9cd7aa007a446bc4935b424545 164 PIRSF PIRSF006092 23 163 2.8E-19 T 29-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 GBCGDNIH2_RS07540 d0a77a9cd7aa007a446bc4935b424545 164 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 90 161 2.2E-18 T 29-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 GBCGDNIH2_RS07540 d0a77a9cd7aa007a446bc4935b424545 164 SUPERFAMILY SSF54534 89 156 8.5E-14 T 29-03-2018 GBCGDNIH2_RS07540 d0a77a9cd7aa007a446bc4935b424545 164 Gene3D G3DSA:3.10.50.30 85 162 1.5E-16 T 29-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 GBCGDNIH2_RS12170 df365b99d93824e8844df511257523f7 307 SUPERFAMILY SSF51735 16 176 1.83E-41 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS12170 df365b99d93824e8844df511257523f7 307 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 17 171 2.6E-38 T 29-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 GBCGDNIH2_RS12170 df365b99d93824e8844df511257523f7 307 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 181 299 3.0E-15 T 29-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 GBCGDNIH2_RS12170 df365b99d93824e8844df511257523f7 307 Gene3D G3DSA:3.40.50.720 1 176 6.0E-32 T 29-03-2018 GBCGDNIH2_RS12170 df365b99d93824e8844df511257523f7 307 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 20 33 - T 29-03-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 GBCGDNIH2_RS12170 df365b99d93824e8844df511257523f7 307 Gene3D G3DSA:1.10.1040.10 177 306 2.1E-21 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 GBCGDNIH2_RS12170 df365b99d93824e8844df511257523f7 307 PIRSF PIRSF000103 10 307 4.2E-83 T 29-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 GBCGDNIH2_RS12170 df365b99d93824e8844df511257523f7 307 SUPERFAMILY SSF48179 181 304 7.03E-25 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 GBCGDNIH2_RS01650 9bf3f4f8004dafc120de0e3a8e06bd4c 375 PIRSF PIRSF000804 1 375 2.8E-107 T 29-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GBCGDNIH2_RS01650 9bf3f4f8004dafc120de0e3a8e06bd4c 375 SUPERFAMILY SSF55979 127 251 7.3E-25 T 29-03-2018 GBCGDNIH2_RS01650 9bf3f4f8004dafc120de0e3a8e06bd4c 375 SUPERFAMILY SSF55979 1 118 3.56E-25 T 29-03-2018 GBCGDNIH2_RS01650 9bf3f4f8004dafc120de0e3a8e06bd4c 375 Gene3D G3DSA:3.10.150.10 255 375 6.6E-24 T 29-03-2018 GBCGDNIH2_RS01650 9bf3f4f8004dafc120de0e3a8e06bd4c 375 SUPERFAMILY SSF55979 252 375 6.28E-29 T 29-03-2018 GBCGDNIH2_RS01650 9bf3f4f8004dafc120de0e3a8e06bd4c 375 Gene3D G3DSA:3.10.150.10 126 254 5.9E-32 T 29-03-2018 GBCGDNIH2_RS01650 9bf3f4f8004dafc120de0e3a8e06bd4c 375 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 253 374 2.0E-25 T 29-03-2018 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GBCGDNIH2_RS01650 9bf3f4f8004dafc120de0e3a8e06bd4c 375 Pfam PF02767 DNA polymerase III beta subunit, central domain 131 250 6.5E-30 T 29-03-2018 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GBCGDNIH2_RS01650 9bf3f4f8004dafc120de0e3a8e06bd4c 375 SMART SM00480 17 371 5.3E-112 T 29-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GBCGDNIH2_RS01650 9bf3f4f8004dafc120de0e3a8e06bd4c 375 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 374 9.0E-81 T 29-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GBCGDNIH2_RS01650 9bf3f4f8004dafc120de0e3a8e06bd4c 375 Gene3D G3DSA:3.10.150.10 1 123 2.7E-27 T 29-03-2018 GBCGDNIH2_RS01650 9bf3f4f8004dafc120de0e3a8e06bd4c 375 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 120 1.0E-30 T 29-03-2018 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GBCGDNIH2_RS12605 481235db31f6204d9bcd9a149c065293 377 ProSitePatterns PS00534 Ferrochelatase signature. 216 234 - T 29-03-2018 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 GBCGDNIH2_RS12605 481235db31f6204d9bcd9a149c065293 377 SUPERFAMILY SSF53800 28 350 1.96E-91 T 29-03-2018 GBCGDNIH2_RS12605 481235db31f6204d9bcd9a149c065293 377 Gene3D G3DSA:3.40.50.1400 194 328 9.6E-35 T 29-03-2018 GBCGDNIH2_RS12605 481235db31f6204d9bcd9a149c065293 377 TIGRFAM TIGR00109 hemH: ferrochelatase 26 345 2.9E-83 T 29-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 GBCGDNIH2_RS12605 481235db31f6204d9bcd9a149c065293 377 Pfam PF00762 Ferrochelatase 30 344 5.4E-102 T 29-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 GBCGDNIH2_RS12605 481235db31f6204d9bcd9a149c065293 377 Hamap MF_00323 Ferrochelatase [hemH]. 28 346 32.908 T 29-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 GBCGDNIH2_RS12605 481235db31f6204d9bcd9a149c065293 377 Gene3D G3DSA:3.40.50.1400 25 193 2.5E-31 T 29-03-2018 GBCGDNIH2_RS09325 ea3e76668bdd672d0b5b819397176008 265 SUPERFAMILY SSF50475 95 232 1.1E-20 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 GBCGDNIH2_RS09325 ea3e76668bdd672d0b5b819397176008 265 Gene3D G3DSA:2.30.110.10 84 235 4.2E-29 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 GBCGDNIH2_RS09325 ea3e76668bdd672d0b5b819397176008 265 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 93 182 4.8E-14 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 GBCGDNIH2_RS09325 ea3e76668bdd672d0b5b819397176008 265 TIGRFAM TIGR04025 PPOX_FMN_DR2398: pyridoxamine 5'-phosphate oxidase, FMN-binding family 70 265 2.2E-77 T 29-03-2018 IPR024029 Pyridoxamine 5-phosphate oxidase, FMN-dependent GBCGDNIH2_RS11195 6a1c60e7c6b6b29ad1bacf3d3a269cb8 571 Gene3D G3DSA:1.25.40.10 202 263 8.1E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS11195 6a1c60e7c6b6b29ad1bacf3d3a269cb8 571 SUPERFAMILY SSF48452 54 275 1.25E-21 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS11195 6a1c60e7c6b6b29ad1bacf3d3a269cb8 571 Pfam PF13432 Tetratricopeptide repeat 83 128 0.0014 T 29-03-2018 GBCGDNIH2_RS11195 6a1c60e7c6b6b29ad1bacf3d3a269cb8 571 Pfam PF13432 Tetratricopeptide repeat 16 76 0.0045 T 29-03-2018 GBCGDNIH2_RS11195 6a1c60e7c6b6b29ad1bacf3d3a269cb8 571 SMART SM00028 181 214 210.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 GBCGDNIH2_RS11195 6a1c60e7c6b6b29ad1bacf3d3a269cb8 571 SMART SM00028 44 77 57.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 GBCGDNIH2_RS11195 6a1c60e7c6b6b29ad1bacf3d3a269cb8 571 SMART SM00028 78 111 25.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 GBCGDNIH2_RS11195 6a1c60e7c6b6b29ad1bacf3d3a269cb8 571 SMART SM00028 147 180 0.015 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 GBCGDNIH2_RS11195 6a1c60e7c6b6b29ad1bacf3d3a269cb8 571 SMART SM00028 250 283 120.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 GBCGDNIH2_RS11195 6a1c60e7c6b6b29ad1bacf3d3a269cb8 571 SMART SM00028 112 145 110.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 GBCGDNIH2_RS11195 6a1c60e7c6b6b29ad1bacf3d3a269cb8 571 Gene3D G3DSA:1.20.58.280 264 411 0.055 T 29-03-2018 GBCGDNIH2_RS11195 6a1c60e7c6b6b29ad1bacf3d3a269cb8 571 Gene3D G3DSA:1.25.40.10 9 80 1.9E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS11195 6a1c60e7c6b6b29ad1bacf3d3a269cb8 571 Gene3D G3DSA:1.25.40.10 81 201 5.3E-22 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS11195 6a1c60e7c6b6b29ad1bacf3d3a269cb8 571 Pfam PF13181 Tetratricopeptide repeat 149 179 0.0049 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 GBCGDNIH2_RS01690 c7a0e808222c8b218db7ad76bfe183e7 381 SUPERFAMILY SSF53756 64 370 2.08E-53 T 29-03-2018 GBCGDNIH2_RS01690 c7a0e808222c8b218db7ad76bfe183e7 381 Pfam PF00534 Glycosyl transferases group 1 190 352 2.2E-26 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 GBCGDNIH2_RS01690 c7a0e808222c8b218db7ad76bfe183e7 381 Gene3D G3DSA:3.40.50.2000 173 357 4.1E-35 T 29-03-2018 GBCGDNIH2_RS08680 499a44902c922010b8ea718245f005b0 516 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 7 516 43.5 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 GBCGDNIH2_RS08680 499a44902c922010b8ea718245f005b0 516 Pfam PF01808 AICARFT/IMPCHase bienzyme 138 450 3.1E-119 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 GBCGDNIH2_RS08680 499a44902c922010b8ea718245f005b0 516 SUPERFAMILY SSF52335 7 196 2.52E-64 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain GBCGDNIH2_RS08680 499a44902c922010b8ea718245f005b0 516 Gene3D G3DSA:3.40.140.20 231 362 7.5E-52 T 29-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 GBCGDNIH2_RS08680 499a44902c922010b8ea718245f005b0 516 Pfam PF02142 MGS-like domain 19 132 7.4E-24 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain GBCGDNIH2_RS08680 499a44902c922010b8ea718245f005b0 516 SUPERFAMILY SSF53927 215 516 2.31E-125 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 GBCGDNIH2_RS08680 499a44902c922010b8ea718245f005b0 516 Gene3D G3DSA:3.40.140.20 365 506 8.4E-49 T 29-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 GBCGDNIH2_RS08680 499a44902c922010b8ea718245f005b0 516 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 8 516 1.2E-202 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 GBCGDNIH2_RS08680 499a44902c922010b8ea718245f005b0 516 Gene3D G3DSA:3.40.50.1380 1 196 3.6E-71 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain GBCGDNIH2_RS08680 499a44902c922010b8ea718245f005b0 516 SMART SM00851 19 133 2.9E-51 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain GBCGDNIH2_RS08680 499a44902c922010b8ea718245f005b0 516 PIRSF PIRSF000414 1 516 1.3E-207 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 GBCGDNIH2_RS08680 499a44902c922010b8ea718245f005b0 516 SMART SM00798 138 451 2.7E-198 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 GBCGDNIH2_RS08500 940cf1bbf29afa61e0b33981ab811eb5 194 TIGRFAM TIGR03384 betaine_BetI: transcriptional repressor BetI 2 190 5.8E-64 T 29-03-2018 IPR017757 Transcriptional repressor BetI GBCGDNIH2_RS08500 940cf1bbf29afa61e0b33981ab811eb5 194 Gene3D G3DSA:1.10.10.60 49 70 2.0E-10 T 29-03-2018 GBCGDNIH2_RS08500 940cf1bbf29afa61e0b33981ab811eb5 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 6.0E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GBCGDNIH2_RS08500 940cf1bbf29afa61e0b33981ab811eb5 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 6.0E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GBCGDNIH2_RS08500 940cf1bbf29afa61e0b33981ab811eb5 194 Hamap MF_00768 HTH-type transcriptional regulator BetI [betI]. 1 194 90.45 T 29-03-2018 IPR017757 Transcriptional repressor BetI GBCGDNIH2_RS08500 940cf1bbf29afa61e0b33981ab811eb5 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 2.0E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GBCGDNIH2_RS08500 940cf1bbf29afa61e0b33981ab811eb5 194 Gene3D G3DSA:1.10.10.60 9 48 8.7E-15 T 29-03-2018 GBCGDNIH2_RS08500 940cf1bbf29afa61e0b33981ab811eb5 194 SUPERFAMILY SSF48498 81 174 2.13E-15 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal GBCGDNIH2_RS08500 940cf1bbf29afa61e0b33981ab811eb5 194 SUPERFAMILY SSF46689 5 79 1.33E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 GBCGDNIH2_RS08500 940cf1bbf29afa61e0b33981ab811eb5 194 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 84 188 1.7E-25 T 29-03-2018 GBCGDNIH2_RS08500 940cf1bbf29afa61e0b33981ab811eb5 194 Gene3D G3DSA:1.10.357.10 71 192 6.3E-5 T 29-03-2018 GBCGDNIH2_RS03265 bed337f439427de6cb9acbb6ce50e598 515 Pfam PF02910 Fumarate reductase flavoprotein C-term 450 482 1.0E-6 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 GBCGDNIH2_RS03265 bed337f439427de6cb9acbb6ce50e598 515 Gene3D G3DSA:3.50.50.60 3 275 9.1E-41 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS03265 bed337f439427de6cb9acbb6ce50e598 515 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 9 475 1.3E-139 T 29-03-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 GBCGDNIH2_RS03265 bed337f439427de6cb9acbb6ce50e598 515 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 335 357 2.5E-10 T 29-03-2018 GBCGDNIH2_RS03265 bed337f439427de6cb9acbb6ce50e598 515 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 2.5E-10 T 29-03-2018 GBCGDNIH2_RS03265 bed337f439427de6cb9acbb6ce50e598 515 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 308 324 2.5E-10 T 29-03-2018 GBCGDNIH2_RS03265 bed337f439427de6cb9acbb6ce50e598 515 SUPERFAMILY SSF56425 225 332 5.38E-32 T 29-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 GBCGDNIH2_RS03265 bed337f439427de6cb9acbb6ce50e598 515 SUPERFAMILY SSF46977 415 476 7.19E-16 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 GBCGDNIH2_RS03265 bed337f439427de6cb9acbb6ce50e598 515 Gene3D G3DSA:3.50.50.60 276 388 4.2E-16 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS03265 bed337f439427de6cb9acbb6ce50e598 515 Gene3D G3DSA:1.20.58.100 447 478 1.2E-8 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 GBCGDNIH2_RS03265 bed337f439427de6cb9acbb6ce50e598 515 Gene3D G3DSA:1.20.58.100 410 446 0.0054 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 GBCGDNIH2_RS03265 bed337f439427de6cb9acbb6ce50e598 515 Pfam PF00890 FAD binding domain 10 372 9.0E-81 T 29-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 GBCGDNIH2_RS03265 bed337f439427de6cb9acbb6ce50e598 515 SUPERFAMILY SSF51905 336 392 3.53E-54 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS03265 bed337f439427de6cb9acbb6ce50e598 515 SUPERFAMILY SSF51905 9 251 3.53E-54 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS06845 4298e77326ccd3f4e1d80ed7e7ee533e 663 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 280 334 - T 29-03-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS06845 4298e77326ccd3f4e1d80ed7e7ee533e 663 Gene3D G3DSA:1.20.210.10 43 561 5.1E-185 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS06845 4298e77326ccd3f4e1d80ed7e7ee533e 663 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 56 504 4.8E-137 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS06845 4298e77326ccd3f4e1d80ed7e7ee533e 663 TIGRFAM TIGR02843 CyoB: cytochrome o ubiquinol oxidase, subunit I 2 647 0.0 T 29-03-2018 IPR014207 Cytochrome o ubiquinol oxidase, subunit I GO:0016682|GO:0055114 MetaCyc: PWY-7544 GBCGDNIH2_RS06845 4298e77326ccd3f4e1d80ed7e7ee533e 663 SUPERFAMILY SSF81442 43 558 2.75E-176 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS06845 4298e77326ccd3f4e1d80ed7e7ee533e 663 Gene3D G3DSA:1.10.287.70 573 640 1.4E-17 T 29-03-2018 GBCGDNIH2_RS06845 4298e77326ccd3f4e1d80ed7e7ee533e 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 97 120 3.1E-91 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS06845 4298e77326ccd3f4e1d80ed7e7ee533e 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 383 401 3.1E-91 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS06845 4298e77326ccd3f4e1d80ed7e7ee533e 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 461 482 3.1E-91 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS06845 4298e77326ccd3f4e1d80ed7e7ee533e 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 166 178 3.1E-91 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS06845 4298e77326ccd3f4e1d80ed7e7ee533e 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 198 216 3.1E-91 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS06845 4298e77326ccd3f4e1d80ed7e7ee533e 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 324 339 3.1E-91 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS06845 4298e77326ccd3f4e1d80ed7e7ee533e 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 348 369 3.1E-91 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS06845 4298e77326ccd3f4e1d80ed7e7ee533e 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 227 246 3.1E-91 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS06845 4298e77326ccd3f4e1d80ed7e7ee533e 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 278 299 3.1E-91 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS06845 4298e77326ccd3f4e1d80ed7e7ee533e 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 411 430 3.1E-91 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS06845 4298e77326ccd3f4e1d80ed7e7ee533e 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 47 72 3.1E-91 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS06845 4298e77326ccd3f4e1d80ed7e7ee533e 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 124 148 3.1E-91 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS02655 f6171b2522c161ddd8ee8a1671f45880 1138 Gene3D G3DSA:3.20.20.70 589 698 9.7E-4 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS02655 f6171b2522c161ddd8ee8a1671f45880 1138 SUPERFAMILY SSF54001 9 342 4.02E-67 T 29-03-2018 GBCGDNIH2_RS02655 f6171b2522c161ddd8ee8a1671f45880 1138 Pfam PF01841 Transglutaminase-like superfamily 149 251 8.9E-18 T 29-03-2018 IPR002931 Transglutaminase-like GBCGDNIH2_RS02655 f6171b2522c161ddd8ee8a1671f45880 1138 Gene3D G3DSA:3.90.260.10 172 291 1.9E-6 T 29-03-2018 IPR002931 Transglutaminase-like GBCGDNIH2_RS02655 f6171b2522c161ddd8ee8a1671f45880 1138 Pfam PF09899 Putative amidoligase enzyme (DUF2126) 281 1135 0.0 T 29-03-2018 IPR018667 Domain of unknown function DUF2126 GBCGDNIH2_RS02655 f6171b2522c161ddd8ee8a1671f45880 1138 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 6 83 9.2E-29 T 29-03-2018 IPR013589 Bacterial transglutaminase-like, N-terminal GBCGDNIH2_RS02655 f6171b2522c161ddd8ee8a1671f45880 1138 SMART SM00460 177 253 1.9E-18 T 29-03-2018 IPR002931 Transglutaminase-like GBCGDNIH2_RS04290 de6500222d0b47c328568ae6e40b16d1 1149 SUPERFAMILY SSF52540 362 461 3.54E-18 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS04290 de6500222d0b47c328568ae6e40b16d1 1149 SUPERFAMILY SSF52540 2 336 8.82E-90 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS04290 de6500222d0b47c328568ae6e40b16d1 1149 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 13 1135 27.93 T 29-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 GBCGDNIH2_RS04290 de6500222d0b47c328568ae6e40b16d1 1149 SUPERFAMILY SSF52540 772 980 1.38E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS04290 de6500222d0b47c328568ae6e40b16d1 1149 SMART SM01058 470 566 2.6E-43 T 29-03-2018 IPR003711 CarD-like/TRCF domain GBCGDNIH2_RS04290 de6500222d0b47c328568ae6e40b16d1 1149 SMART SM00982 996 1096 3.2E-42 T 29-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 GBCGDNIH2_RS04290 de6500222d0b47c328568ae6e40b16d1 1149 Gene3D G3DSA:3.40.50.300 350 771 1.8E-34 T 29-03-2018 GBCGDNIH2_RS04290 de6500222d0b47c328568ae6e40b16d1 1149 SMART SM00487 590 780 6.1E-34 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain GBCGDNIH2_RS04290 de6500222d0b47c328568ae6e40b16d1 1149 Pfam PF00271 Helicase conserved C-terminal domain 798 899 3.1E-15 T 29-03-2018 IPR001650 Helicase, C-terminal GBCGDNIH2_RS04290 de6500222d0b47c328568ae6e40b16d1 1149 Pfam PF03461 TRCF domain 998 1089 4.9E-25 T 29-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 GBCGDNIH2_RS04290 de6500222d0b47c328568ae6e40b16d1 1149 SUPERFAMILY SSF143517 987 1139 1.83E-33 T 29-03-2018 GBCGDNIH2_RS04290 de6500222d0b47c328568ae6e40b16d1 1149 SUPERFAMILY SSF52540 515 774 3.24E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS04290 de6500222d0b47c328568ae6e40b16d1 1149 Pfam PF02559 CarD-like/TRCF domain 473 564 2.9E-23 T 29-03-2018 IPR003711 CarD-like/TRCF domain GBCGDNIH2_RS04290 de6500222d0b47c328568ae6e40b16d1 1149 SMART SM00490 816 900 7.2E-17 T 29-03-2018 IPR001650 Helicase, C-terminal GBCGDNIH2_RS04290 de6500222d0b47c328568ae6e40b16d1 1149 SUPERFAMILY SSF141259 462 538 4.97E-19 T 29-03-2018 IPR003711 CarD-like/TRCF domain GBCGDNIH2_RS04290 de6500222d0b47c328568ae6e40b16d1 1149 Pfam PF00270 DEAD/DEAH box helicase 595 754 3.2E-16 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 GBCGDNIH2_RS04290 de6500222d0b47c328568ae6e40b16d1 1149 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 133 1070 0.0 T 29-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 GBCGDNIH2_RS04290 de6500222d0b47c328568ae6e40b16d1 1149 Gene3D G3DSA:3.40.50.300 787 946 4.2E-22 T 29-03-2018 GBCGDNIH2_RS09465 c9f79c848224931bd08811c34b5e0a4a 197 SUPERFAMILY SSF101738 11 124 3.14E-43 T 29-03-2018 IPR007481 Stringent starvation protein B GBCGDNIH2_RS09465 c9f79c848224931bd08811c34b5e0a4a 197 Pfam PF04386 Stringent starvation protein B 18 187 2.4E-48 T 29-03-2018 IPR007481 Stringent starvation protein B GBCGDNIH2_RS09465 c9f79c848224931bd08811c34b5e0a4a 197 Gene3D G3DSA:2.30.30.220 9 124 7.8E-48 T 29-03-2018 IPR007481 Stringent starvation protein B GBCGDNIH2_RS06390 739cbd66cac66b945cfcf996a62a6cfa 416 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 186 415 2.8E-82 T 29-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 GBCGDNIH2_RS06390 739cbd66cac66b945cfcf996a62a6cfa 416 SUPERFAMILY SSF51230 1 96 1.09E-28 T 29-03-2018 IPR011053 Single hybrid motif GBCGDNIH2_RS06390 739cbd66cac66b945cfcf996a62a6cfa 416 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 GBCGDNIH2_RS06390 739cbd66cac66b945cfcf996a62a6cfa 416 Pfam PF02817 e3 binding domain 127 162 3.7E-16 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 GBCGDNIH2_RS06390 739cbd66cac66b945cfcf996a62a6cfa 416 SUPERFAMILY SSF52777 186 416 1.82E-80 T 29-03-2018 GBCGDNIH2_RS06390 739cbd66cac66b945cfcf996a62a6cfa 416 Pfam PF00364 Biotin-requiring enzyme 4 77 1.8E-20 T 29-03-2018 IPR000089 Biotin/lipoyl attachment GBCGDNIH2_RS06390 739cbd66cac66b945cfcf996a62a6cfa 416 Gene3D G3DSA:3.90.1170.30 1 49 1.2E-16 T 29-03-2018 GBCGDNIH2_RS06390 739cbd66cac66b945cfcf996a62a6cfa 416 TIGRFAM TIGR01349 PDHac_trf_mito: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase 5 416 4.7E-161 T 29-03-2018 IPR006257 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex GO:0004742|GO:0006090|GO:0045254 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-70268 GBCGDNIH2_RS06390 739cbd66cac66b945cfcf996a62a6cfa 416 Gene3D G3DSA:4.10.320.10 110 176 9.7E-20 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 GBCGDNIH2_RS06390 739cbd66cac66b945cfcf996a62a6cfa 416 SUPERFAMILY SSF47005 123 165 5.49E-12 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 GBCGDNIH2_RS06390 739cbd66cac66b945cfcf996a62a6cfa 416 Gene3D G3DSA:3.30.559.10 177 416 7.9E-90 T 29-03-2018 GBCGDNIH2_RS05130 588996c7f2455ac336434d8ea2404c8e 341 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 283 311 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 GBCGDNIH2_RS05130 588996c7f2455ac336434d8ea2404c8e 341 TIGRFAM TIGR01853 lipid_A_lpxD: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD 24 340 6.4E-108 T 29-03-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 GBCGDNIH2_RS05130 588996c7f2455ac336434d8ea2404c8e 341 Pfam PF04613 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD 39 106 3.6E-22 T 29-03-2018 IPR020573 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, non-repeat region GO:0009245|GO:0016747 GBCGDNIH2_RS05130 588996c7f2455ac336434d8ea2404c8e 341 Gene3D G3DSA:2.160.10.10 222 340 1.3E-25 T 29-03-2018 GBCGDNIH2_RS05130 588996c7f2455ac336434d8ea2404c8e 341 Hamap MF_00523 UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase [lpxD]. 24 341 35.589 T 29-03-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 GBCGDNIH2_RS05130 588996c7f2455ac336434d8ea2404c8e 341 Gene3D G3DSA:2.160.10.10 105 159 5.0E-11 T 29-03-2018 GBCGDNIH2_RS05130 588996c7f2455ac336434d8ea2404c8e 341 Gene3D G3DSA:2.160.10.10 160 221 2.9E-15 T 29-03-2018 GBCGDNIH2_RS05130 588996c7f2455ac336434d8ea2404c8e 341 SUPERFAMILY SSF51161 47 331 2.93E-77 T 29-03-2018 IPR011004 Trimeric LpxA-like GBCGDNIH2_RS05130 588996c7f2455ac336434d8ea2404c8e 341 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 274 307 0.0012 T 29-03-2018 IPR001451 Hexapeptide repeat GBCGDNIH2_RS05130 588996c7f2455ac336434d8ea2404c8e 341 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 132 160 6.6E-8 T 29-03-2018 IPR001451 Hexapeptide repeat GBCGDNIH2_RS05130 588996c7f2455ac336434d8ea2404c8e 341 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 238 273 3.5E-5 T 29-03-2018 IPR001451 Hexapeptide repeat GBCGDNIH2_RS05130 588996c7f2455ac336434d8ea2404c8e 341 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 162 195 9.4E-4 T 29-03-2018 IPR001451 Hexapeptide repeat GBCGDNIH2_RS04945 0e6a56b1ceac7acda9d5b3a74360f321 567 Gene3D G3DSA:3.30.413.10 423 563 5.0E-24 T 29-03-2018 GBCGDNIH2_RS04945 0e6a56b1ceac7acda9d5b3a74360f321 567 SUPERFAMILY SSF55124 8 140 7.03E-29 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 GBCGDNIH2_RS04945 0e6a56b1ceac7acda9d5b3a74360f321 567 SUPERFAMILY SSF56014 426 562 8.9E-31 T 29-03-2018 GBCGDNIH2_RS04945 0e6a56b1ceac7acda9d5b3a74360f321 567 PRINTS PR00397 Sirohaem Fe-binding site signature 475 493 1.5E-8 T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 GBCGDNIH2_RS04945 0e6a56b1ceac7acda9d5b3a74360f321 567 PRINTS PR00397 Sirohaem Fe-binding site signature 427 445 1.5E-8 T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 GBCGDNIH2_RS04945 0e6a56b1ceac7acda9d5b3a74360f321 567 SUPERFAMILY SSF56014 141 337 5.23E-46 T 29-03-2018 GBCGDNIH2_RS04945 0e6a56b1ceac7acda9d5b3a74360f321 567 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 68 130 4.4E-19 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 GBCGDNIH2_RS04945 0e6a56b1ceac7acda9d5b3a74360f321 567 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 345 414 9.5E-10 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 GBCGDNIH2_RS04945 0e6a56b1ceac7acda9d5b3a74360f321 567 Gene3D G3DSA:3.30.413.10 136 338 5.7E-41 T 29-03-2018 GBCGDNIH2_RS04945 0e6a56b1ceac7acda9d5b3a74360f321 567 Gene3D G3DSA:3.30.413.10 72 135 1.1E-5 T 29-03-2018 GBCGDNIH2_RS04945 0e6a56b1ceac7acda9d5b3a74360f321 567 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 475 491 - T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 GBCGDNIH2_RS04945 0e6a56b1ceac7acda9d5b3a74360f321 567 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 166 327 4.2E-40 T 29-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 GBCGDNIH2_RS04945 0e6a56b1ceac7acda9d5b3a74360f321 567 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 472 561 2.9E-7 T 29-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 GBCGDNIH2_RS04945 0e6a56b1ceac7acda9d5b3a74360f321 567 SUPERFAMILY SSF55124 342 417 6.71E-16 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 GBCGDNIH2_RS05360 a1aacba6c8ce32c03c36ece6a2f51d92 760 Gene3D G3DSA:3.30.460.10 224 360 2.5E-39 T 29-03-2018 GBCGDNIH2_RS05360 a1aacba6c8ce32c03c36ece6a2f51d92 760 Gene3D G3DSA:3.30.70.260 680 760 1.1E-5 T 29-03-2018 GBCGDNIH2_RS05360 a1aacba6c8ce32c03c36ece6a2f51d92 760 Pfam PF13328 HD domain 57 207 1.4E-47 T 29-03-2018 IPR003607 HD/PDEase domain GBCGDNIH2_RS05360 a1aacba6c8ce32c03c36ece6a2f51d92 760 SMART SM00471 72 184 1.1E-7 T 29-03-2018 IPR003607 HD/PDEase domain GBCGDNIH2_RS05360 a1aacba6c8ce32c03c36ece6a2f51d92 760 SUPERFAMILY SSF81301 212 426 2.29E-56 T 29-03-2018 GBCGDNIH2_RS05360 a1aacba6c8ce32c03c36ece6a2f51d92 760 Pfam PF04607 Region found in RelA / SpoT proteins 268 380 7.7E-34 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 GBCGDNIH2_RS05360 a1aacba6c8ce32c03c36ece6a2f51d92 760 Pfam PF02824 TGS domain 423 481 4.0E-22 T 29-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 GBCGDNIH2_RS05360 a1aacba6c8ce32c03c36ece6a2f51d92 760 Pfam PF13291 ACT domain 682 757 2.1E-23 T 29-03-2018 IPR002912 ACT domain GBCGDNIH2_RS05360 a1aacba6c8ce32c03c36ece6a2f51d92 760 SMART SM00954 268 380 6.3E-60 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 GBCGDNIH2_RS05360 a1aacba6c8ce32c03c36ece6a2f51d92 760 SUPERFAMILY SSF109604 37 222 8.47E-65 T 29-03-2018 GBCGDNIH2_RS05360 a1aacba6c8ce32c03c36ece6a2f51d92 760 SUPERFAMILY SSF81271 409 481 1.44E-22 T 29-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 GBCGDNIH2_RS05360 a1aacba6c8ce32c03c36ece6a2f51d92 760 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 57 756 3.0E-209 T 29-03-2018 IPR004811 RelA/SpoT family GO:0015969 GBCGDNIH2_RS05360 a1aacba6c8ce32c03c36ece6a2f51d92 760 Gene3D G3DSA:3.10.20.30 416 489 2.0E-24 T 29-03-2018 IPR012675 Beta-grasp domain GBCGDNIH2_RS03595 7b0bf3efdfa8ebfe9b51510fc6be625f 493 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 148 459 7.4E-30 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS03595 7b0bf3efdfa8ebfe9b51510fc6be625f 493 Gene3D G3DSA:3.50.50.60 242 319 1.6E-22 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS03595 7b0bf3efdfa8ebfe9b51510fc6be625f 493 Gene3D G3DSA:3.50.50.60 320 403 1.2E-19 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS03595 7b0bf3efdfa8ebfe9b51510fc6be625f 493 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 25 134 2.2E-37 T 29-03-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 GBCGDNIH2_RS03595 7b0bf3efdfa8ebfe9b51510fc6be625f 493 Gene3D G3DSA:1.10.1060.10 2 143 5.4E-40 T 29-03-2018 GBCGDNIH2_RS03595 7b0bf3efdfa8ebfe9b51510fc6be625f 493 TIGRFAM TIGR01318 gltD_gamma_fam: glutamate synthase, small subunit 7 471 1.0E-157 T 29-03-2018 IPR006006 Glutamate synthase, NADH/NADPH, small subunit 2 GO:0006537|GO:0016639 GBCGDNIH2_RS03595 7b0bf3efdfa8ebfe9b51510fc6be625f 493 Gene3D G3DSA:3.40.50.720 144 241 6.0E-18 T 29-03-2018 GBCGDNIH2_RS03595 7b0bf3efdfa8ebfe9b51510fc6be625f 493 Gene3D G3DSA:3.50.50.60 406 488 7.4E-12 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS03595 7b0bf3efdfa8ebfe9b51510fc6be625f 493 SUPERFAMILY SSF51971 148 403 1.94E-67 T 29-03-2018 GBCGDNIH2_RS03595 7b0bf3efdfa8ebfe9b51510fc6be625f 493 PRINTS PR00419 Adrenodoxin reductase family signature 328 341 4.3E-31 T 29-03-2018 GBCGDNIH2_RS03595 7b0bf3efdfa8ebfe9b51510fc6be625f 493 PRINTS PR00419 Adrenodoxin reductase family signature 148 170 4.3E-31 T 29-03-2018 GBCGDNIH2_RS03595 7b0bf3efdfa8ebfe9b51510fc6be625f 493 PRINTS PR00419 Adrenodoxin reductase family signature 213 223 4.3E-31 T 29-03-2018 GBCGDNIH2_RS03595 7b0bf3efdfa8ebfe9b51510fc6be625f 493 PRINTS PR00419 Adrenodoxin reductase family signature 171 184 4.3E-31 T 29-03-2018 GBCGDNIH2_RS03595 7b0bf3efdfa8ebfe9b51510fc6be625f 493 PRINTS PR00419 Adrenodoxin reductase family signature 294 308 4.3E-31 T 29-03-2018 GBCGDNIH2_RS03595 7b0bf3efdfa8ebfe9b51510fc6be625f 493 SUPERFAMILY SSF46548 5 157 1.78E-37 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 GBCGDNIH2_RS11810 04c4dc4f184549a278df6208f623e263 447 Gene3D G3DSA:3.30.465.10 68 193 5.6E-22 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 GBCGDNIH2_RS11810 04c4dc4f184549a278df6208f623e263 447 SUPERFAMILY SSF56176 15 190 4.49E-28 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 GBCGDNIH2_RS11810 04c4dc4f184549a278df6208f623e263 447 Pfam PF01565 FAD binding domain 48 157 8.0E-16 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 GBCGDNIH2_RS08545 79921f4052c3a7282f61b1c6c399f3b7 86 SUPERFAMILY SSF50037 4 76 3.2E-12 T 29-03-2018 IPR008988 Transcriptional repressor, C-terminal GBCGDNIH2_RS08545 79921f4052c3a7282f61b1c6c399f3b7 86 Gene3D G3DSA:2.30.30.90 1 82 1.6E-17 T 29-03-2018 GBCGDNIH2_RS08545 79921f4052c3a7282f61b1c6c399f3b7 86 SMART SM00899 1 77 7.0E-17 T 29-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 GBCGDNIH2_RS08545 79921f4052c3a7282f61b1c6c399f3b7 86 Pfam PF04023 FeoA domain 1 75 7.5E-14 T 29-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 GBCGDNIH2_RS02885 5e0c9fde49dad6856143d0c04905f295 122 Gene3D G3DSA:2.40.150.20 1 122 4.2E-52 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 GBCGDNIH2_RS02885 5e0c9fde49dad6856143d0c04905f295 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 2.0E-56 T 29-03-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 GBCGDNIH2_RS02885 5e0c9fde49dad6856143d0c04905f295 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 3.0E-54 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 GBCGDNIH2_RS02885 5e0c9fde49dad6856143d0c04905f295 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 27.759 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 GBCGDNIH2_RS02885 5e0c9fde49dad6856143d0c04905f295 122 SUPERFAMILY SSF50193 1 122 1.28E-50 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 GBCGDNIH2_RS02885 5e0c9fde49dad6856143d0c04905f295 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 29-03-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02885 5e0c9fde49dad6856143d0c04905f295 122 SMART SM01374 1 122 8.5E-83 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 GBCGDNIH2_RS02270 d16a4f8c3e2138c008c9aebe856ac5d8 276 SMART SM00271 210 275 1.9E-5 T 29-03-2018 IPR001623 DnaJ domain GBCGDNIH2_RS02270 d16a4f8c3e2138c008c9aebe856ac5d8 276 Pfam PF05099 Tellurite resistance protein TerB 77 195 1.7E-27 T 29-03-2018 IPR007791 Co-chaperone DjlA, N-terminal GBCGDNIH2_RS02270 d16a4f8c3e2138c008c9aebe856ac5d8 276 SUPERFAMILY SSF46565 204 272 2.36E-11 T 29-03-2018 IPR001623 DnaJ domain GBCGDNIH2_RS02270 d16a4f8c3e2138c008c9aebe856ac5d8 276 SUPERFAMILY SSF158682 72 224 1.96E-15 T 29-03-2018 GBCGDNIH2_RS02270 d16a4f8c3e2138c008c9aebe856ac5d8 276 SUPERFAMILY SSF158682 12 21 1.96E-15 T 29-03-2018 GBCGDNIH2_RS02270 d16a4f8c3e2138c008c9aebe856ac5d8 276 Gene3D G3DSA:1.10.287.110 195 273 3.9E-8 T 29-03-2018 IPR001623 DnaJ domain GBCGDNIH2_RS02270 d16a4f8c3e2138c008c9aebe856ac5d8 276 Gene3D G3DSA:1.10.3680.10 61 194 6.5E-16 T 29-03-2018 IPR029024 TerB-like GBCGDNIH2_RS12335 0c7fdb1bcc6a081fe2e48b77102aeb79 348 Gene3D G3DSA:3.40.630.30 148 344 1.7E-20 T 29-03-2018 GBCGDNIH2_RS12335 0c7fdb1bcc6a081fe2e48b77102aeb79 348 Pfam PF13523 Acetyltransferase (GNAT) domain 183 327 6.9E-52 T 29-03-2018 GBCGDNIH2_RS12335 0c7fdb1bcc6a081fe2e48b77102aeb79 348 SUPERFAMILY SSF55729 148 340 2.6E-57 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase GBCGDNIH2_RS12335 0c7fdb1bcc6a081fe2e48b77102aeb79 348 SMART SM01006 179 226 1.3E-21 T 29-03-2018 IPR019432 Siderophore biosynthesis protein, conserved domain GBCGDNIH2_RS12195 449455183c47a665ca0c51d2857e33a2 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 5 89 6.6E-38 T 29-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS12195 449455183c47a665ca0c51d2857e33a2 89 Pfam PF00312 Ribosomal protein S15 10 88 6.4E-37 T 29-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS12195 449455183c47a665ca0c51d2857e33a2 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 29-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS12195 449455183c47a665ca0c51d2857e33a2 89 SUPERFAMILY SSF47060 3 89 9.12E-35 T 29-03-2018 IPR009068 S15/NS1, RNA-binding GBCGDNIH2_RS12195 449455183c47a665ca0c51d2857e33a2 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 12 88 8.0E-31 T 29-03-2018 GBCGDNIH2_RS12195 449455183c47a665ca0c51d2857e33a2 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 22.481 T 29-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS12195 449455183c47a665ca0c51d2857e33a2 89 Gene3D G3DSA:1.10.287.10 2 89 1.8E-34 T 29-03-2018 GBCGDNIH2_RS12195 449455183c47a665ca0c51d2857e33a2 89 SMART SM01387 8 88 7.7E-51 T 29-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS04220 2b60e0146baa7c70f6ed2685dd156d3f 552 Gene3D G3DSA:1.25.40.10 2 56 7.3E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS04220 2b60e0146baa7c70f6ed2685dd156d3f 552 Gene3D G3DSA:1.25.40.10 158 196 1.3E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS04220 2b60e0146baa7c70f6ed2685dd156d3f 552 SUPERFAMILY SSF53756 260 508 4.6E-25 T 29-03-2018 GBCGDNIH2_RS04220 2b60e0146baa7c70f6ed2685dd156d3f 552 SUPERFAMILY SSF48452 5 233 1.9E-31 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS04220 2b60e0146baa7c70f6ed2685dd156d3f 552 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 444 498 4.7E-7 T 29-03-2018 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 GBCGDNIH2_RS04220 2b60e0146baa7c70f6ed2685dd156d3f 552 Pfam PF13432 Tetratricopeptide repeat 10 73 7.2E-4 T 29-03-2018 GBCGDNIH2_RS04220 2b60e0146baa7c70f6ed2685dd156d3f 552 Gene3D G3DSA:3.40.50.2000 349 522 3.3E-34 T 29-03-2018 GBCGDNIH2_RS04220 2b60e0146baa7c70f6ed2685dd156d3f 552 Gene3D G3DSA:1.20.58.280 82 101 0.049 T 29-03-2018 GBCGDNIH2_RS04220 2b60e0146baa7c70f6ed2685dd156d3f 552 Gene3D G3DSA:1.25.40.10 57 81 1.4E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS04220 2b60e0146baa7c70f6ed2685dd156d3f 552 Gene3D G3DSA:1.25.40.10 197 229 3.8E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS04220 2b60e0146baa7c70f6ed2685dd156d3f 552 Gene3D G3DSA:1.25.40.10 102 157 4.6E-15 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS04220 2b60e0146baa7c70f6ed2685dd156d3f 552 Pfam PF13429 Tetratricopeptide repeat 88 203 1.9E-8 T 29-03-2018 GBCGDNIH2_RS04220 2b60e0146baa7c70f6ed2685dd156d3f 552 SMART SM00028 5 38 3.8 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 GBCGDNIH2_RS04220 2b60e0146baa7c70f6ed2685dd156d3f 552 SMART SM00028 107 140 38.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 GBCGDNIH2_RS04220 2b60e0146baa7c70f6ed2685dd156d3f 552 SMART SM00028 39 72 20.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 GBCGDNIH2_RS04220 2b60e0146baa7c70f6ed2685dd156d3f 552 SMART SM00028 141 174 46.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 GBCGDNIH2_RS04220 2b60e0146baa7c70f6ed2685dd156d3f 552 SMART SM00028 73 106 2.4 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 GBCGDNIH2_RS04220 2b60e0146baa7c70f6ed2685dd156d3f 552 SMART SM00028 175 208 0.11 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 GBCGDNIH2_RS01275 ad153c84be224ce0935a84e959945382 294 Pfam PF00085 Thioredoxin 6 109 8.5E-23 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 GBCGDNIH2_RS01275 ad153c84be224ce0935a84e959945382 294 ProSitePatterns PS00194 Thioredoxin family active site. 24 42 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 GBCGDNIH2_RS01275 ad153c84be224ce0935a84e959945382 294 SUPERFAMILY SSF52833 6 114 7.27E-30 T 29-03-2018 IPR012336 Thioredoxin-like fold GBCGDNIH2_RS01275 ad153c84be224ce0935a84e959945382 294 Gene3D G3DSA:1.25.40.10 122 209 1.7E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS01275 ad153c84be224ce0935a84e959945382 294 Gene3D G3DSA:3.40.30.10 2 116 2.2E-26 T 29-03-2018 GBCGDNIH2_RS01275 ad153c84be224ce0935a84e959945382 294 PRINTS PR00421 Thioredoxin family signature 76 87 3.5E-5 T 29-03-2018 GBCGDNIH2_RS01275 ad153c84be224ce0935a84e959945382 294 PRINTS PR00421 Thioredoxin family signature 31 40 3.5E-5 T 29-03-2018 GBCGDNIH2_RS01275 ad153c84be224ce0935a84e959945382 294 PRINTS PR00421 Thioredoxin family signature 23 31 3.5E-5 T 29-03-2018 GBCGDNIH2_RS01275 ad153c84be224ce0935a84e959945382 294 SUPERFAMILY SSF48452 129 178 1.14E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS01275 ad153c84be224ce0935a84e959945382 294 SUPERFAMILY SSF48452 205 256 1.14E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS01275 ad153c84be224ce0935a84e959945382 294 Pfam PF14561 Tetratricopeptide repeat 206 293 5.7E-28 T 29-03-2018 GBCGDNIH2_RS01275 ad153c84be224ce0935a84e959945382 294 Gene3D G3DSA:1.25.40.10 210 293 2.6E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS01275 ad153c84be224ce0935a84e959945382 294 Pfam PF14559 Tetratricopeptide repeat 133 186 5.3E-7 T 29-03-2018 GBCGDNIH2_RS06605 15fd0ce59e26c6b35925e222401fa72b 350 Pfam PF01207 Dihydrouridine synthase (Dus) 24 331 8.8E-103 T 29-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 GBCGDNIH2_RS06605 15fd0ce59e26c6b35925e222401fa72b 350 Gene3D G3DSA:3.20.20.70 17 262 4.7E-55 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS06605 15fd0ce59e26c6b35925e222401fa72b 350 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 17 333 1.8E-111 T 29-03-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 GBCGDNIH2_RS06605 15fd0ce59e26c6b35925e222401fa72b 350 PIRSF PIRSF006621 14 342 1.8E-103 T 29-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 GBCGDNIH2_RS06605 15fd0ce59e26c6b35925e222401fa72b 350 Gene3D G3DSA:1.10.1200.80 267 345 2.8E-21 T 29-03-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 GBCGDNIH2_RS06605 15fd0ce59e26c6b35925e222401fa72b 350 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 108 127 - T 29-03-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 GBCGDNIH2_RS06605 15fd0ce59e26c6b35925e222401fa72b 350 SUPERFAMILY SSF51395 22 333 1.48E-86 T 29-03-2018 GBCGDNIH2_RS10970 70879757bfcfdff12b807e6120db459a 933 PRINTS PR00344 Bacterial sensor protein C-terminal signature 712 722 1.0E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS10970 70879757bfcfdff12b807e6120db459a 933 PRINTS PR00344 Bacterial sensor protein C-terminal signature 694 708 1.0E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS10970 70879757bfcfdff12b807e6120db459a 933 PRINTS PR00344 Bacterial sensor protein C-terminal signature 725 743 1.0E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS10970 70879757bfcfdff12b807e6120db459a 933 PRINTS PR00344 Bacterial sensor protein C-terminal signature 749 762 1.0E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS10970 70879757bfcfdff12b807e6120db459a 933 Gene3D G3DSA:3.30.450.20 396 518 4.2E-25 T 29-03-2018 GBCGDNIH2_RS10970 70879757bfcfdff12b807e6120db459a 933 SUPERFAMILY SSF55785 141 252 1.77E-14 T 29-03-2018 IPR000014 PAS domain GBCGDNIH2_RS10970 70879757bfcfdff12b807e6120db459a 933 Pfam PF00072 Response regulator receiver domain 796 914 6.9E-15 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GBCGDNIH2_RS10970 70879757bfcfdff12b807e6120db459a 933 SMART SM00091 394 460 8.7E-8 T 29-03-2018 IPR000014 PAS domain GBCGDNIH2_RS10970 70879757bfcfdff12b807e6120db459a 933 SMART SM00091 130 197 2.4 T 29-03-2018 IPR000014 PAS domain GBCGDNIH2_RS10970 70879757bfcfdff12b807e6120db459a 933 SMART SM00091 256 323 3.2E-11 T 29-03-2018 IPR000014 PAS domain GBCGDNIH2_RS10970 70879757bfcfdff12b807e6120db459a 933 SMART SM00387 633 765 7.6E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS10970 70879757bfcfdff12b807e6120db459a 933 SMART SM00086 328 371 5.2E-9 T 29-03-2018 IPR001610 PAC motif GBCGDNIH2_RS10970 70879757bfcfdff12b807e6120db459a 933 SMART SM00086 202 244 22.0 T 29-03-2018 IPR001610 PAC motif GBCGDNIH2_RS10970 70879757bfcfdff12b807e6120db459a 933 SMART SM00086 466 502 4.3 T 29-03-2018 IPR001610 PAC motif GBCGDNIH2_RS10970 70879757bfcfdff12b807e6120db459a 933 Gene3D G3DSA:3.40.50.2300 785 932 9.0E-22 T 29-03-2018 GBCGDNIH2_RS10970 70879757bfcfdff12b807e6120db459a 933 Gene3D G3DSA:1.10.287.130 519 588 2.4E-9 T 29-03-2018 GBCGDNIH2_RS10970 70879757bfcfdff12b807e6120db459a 933 Pfam PF08447 PAS fold 278 363 2.9E-17 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 GBCGDNIH2_RS10970 70879757bfcfdff12b807e6120db459a 933 Pfam PF08447 PAS fold 417 488 1.4E-11 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 GBCGDNIH2_RS10970 70879757bfcfdff12b807e6120db459a 933 SUPERFAMILY SSF52172 794 928 3.7E-25 T 29-03-2018 IPR011006 CheY-like superfamily GBCGDNIH2_RS10970 70879757bfcfdff12b807e6120db459a 933 SUPERFAMILY SSF47384 516 589 4.51E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GBCGDNIH2_RS10970 70879757bfcfdff12b807e6120db459a 933 Gene3D G3DSA:3.30.565.10 597 779 5.8E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS10970 70879757bfcfdff12b807e6120db459a 933 Pfam PF00512 His Kinase A (phospho-acceptor) domain 525 590 2.9E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GBCGDNIH2_RS10970 70879757bfcfdff12b807e6120db459a 933 SUPERFAMILY SSF55874 583 766 1.2E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS10970 70879757bfcfdff12b807e6120db459a 933 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 254 378 9.1E-18 T 29-03-2018 IPR000014 PAS domain GBCGDNIH2_RS10970 70879757bfcfdff12b807e6120db459a 933 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 134 251 1.5E-9 T 29-03-2018 IPR000014 PAS domain GBCGDNIH2_RS10970 70879757bfcfdff12b807e6120db459a 933 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 397 507 1.7E-12 T 29-03-2018 IPR000014 PAS domain GBCGDNIH2_RS10970 70879757bfcfdff12b807e6120db459a 933 SMART SM00388 524 592 2.2E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GBCGDNIH2_RS10970 70879757bfcfdff12b807e6120db459a 933 Gene3D G3DSA:3.30.450.20 248 395 1.7E-39 T 29-03-2018 GBCGDNIH2_RS10970 70879757bfcfdff12b807e6120db459a 933 SMART SM00448 794 914 1.2E-16 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GBCGDNIH2_RS10970 70879757bfcfdff12b807e6120db459a 933 SUPERFAMILY SSF55785 403 501 4.51E-18 T 29-03-2018 IPR000014 PAS domain GBCGDNIH2_RS10970 70879757bfcfdff12b807e6120db459a 933 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 634 762 1.2E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS10970 70879757bfcfdff12b807e6120db459a 933 SUPERFAMILY SSF55785 241 368 2.24E-27 T 29-03-2018 IPR000014 PAS domain GBCGDNIH2_RS10970 70879757bfcfdff12b807e6120db459a 933 Gene3D G3DSA:3.30.450.20 127 247 1.1E-20 T 29-03-2018 GBCGDNIH2_RS10970 70879757bfcfdff12b807e6120db459a 933 Pfam PF08448 PAS fold 138 246 1.2E-12 T 29-03-2018 IPR013656 PAS fold-4 GBCGDNIH2_RS06195 0dce217d8a3a2a5aa8362044b85614d4 428 Gene3D G3DSA:3.40.50.150 217 428 6.5E-58 T 29-03-2018 GBCGDNIH2_RS06195 0dce217d8a3a2a5aa8362044b85614d4 428 Pfam PF01189 16S rRNA methyltransferase RsmB/F 233 422 8.3E-45 T 29-03-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 GBCGDNIH2_RS06195 0dce217d8a3a2a5aa8362044b85614d4 428 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 237 247 7.4E-29 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 GBCGDNIH2_RS06195 0dce217d8a3a2a5aa8362044b85614d4 428 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 305 317 7.4E-29 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 GBCGDNIH2_RS06195 0dce217d8a3a2a5aa8362044b85614d4 428 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 355 371 7.4E-29 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 GBCGDNIH2_RS06195 0dce217d8a3a2a5aa8362044b85614d4 428 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 407 424 7.4E-29 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 GBCGDNIH2_RS06195 0dce217d8a3a2a5aa8362044b85614d4 428 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 208 222 7.4E-29 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 GBCGDNIH2_RS06195 0dce217d8a3a2a5aa8362044b85614d4 428 Gene3D G3DSA:3.30.70.1170 159 216 1.6E-15 T 29-03-2018 GBCGDNIH2_RS06195 0dce217d8a3a2a5aa8362044b85614d4 428 SUPERFAMILY SSF53335 122 424 2.34E-70 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GBCGDNIH2_RS06195 0dce217d8a3a2a5aa8362044b85614d4 428 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 304 315 - T 29-03-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 GBCGDNIH2_RS02615 568835e0788fd25e754c7a7fcc32c9e9 648 PIRSF PIRSF000549 1 648 1.0E-278 T 29-03-2018 IPR016230 Serine-protein kinase, PrkA GO:0004672 GBCGDNIH2_RS02615 568835e0788fd25e754c7a7fcc32c9e9 648 SMART SM00763 23 384 1.3E-196 T 29-03-2018 IPR013153 PrkA AAA domain GBCGDNIH2_RS02615 568835e0788fd25e754c7a7fcc32c9e9 648 SUPERFAMILY SSF52540 79 353 8.69E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS02615 568835e0788fd25e754c7a7fcc32c9e9 648 Pfam PF06798 PrkA serine protein kinase C-terminal domain 387 640 1.0E-74 T 29-03-2018 IPR010650 PrkA C-terminal domain GBCGDNIH2_RS02615 568835e0788fd25e754c7a7fcc32c9e9 648 Gene3D G3DSA:3.40.50.300 71 357 2.2E-9 T 29-03-2018 GBCGDNIH2_RS02615 568835e0788fd25e754c7a7fcc32c9e9 648 Pfam PF08298 PrkA AAA domain 23 381 1.1E-169 T 29-03-2018 IPR013153 PrkA AAA domain GBCGDNIH2_RS03500 95e4da2afed69ed9d2d5d1a172411de4 280 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 136 169 9.2E-5 T 29-03-2018 IPR001451 Hexapeptide repeat GBCGDNIH2_RS03500 95e4da2afed69ed9d2d5d1a172411de4 280 Hamap MF_00811 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 3 280 55.073 T 29-03-2018 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 GBCGDNIH2_RS03500 95e4da2afed69ed9d2d5d1a172411de4 280 Gene3D G3DSA:1.10.166.10 5 71 8.6E-26 T 29-03-2018 IPR023180 Tetrahydrodipicolinate-N-succinyltransferase, chain A, domain 1 KEGG: 00300+2.3.1.117 GBCGDNIH2_RS03500 95e4da2afed69ed9d2d5d1a172411de4 280 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 178 213 3.0E-10 T 29-03-2018 IPR001451 Hexapeptide repeat GBCGDNIH2_RS03500 95e4da2afed69ed9d2d5d1a172411de4 280 SUPERFAMILY SSF51161 6 264 4.44E-68 T 29-03-2018 IPR011004 Trimeric LpxA-like GBCGDNIH2_RS03500 95e4da2afed69ed9d2d5d1a172411de4 280 Pfam PF14805 Tetrahydrodipicolinate N-succinyltransferase N-terminal 6 71 6.2E-24 T 29-03-2018 IPR023180 Tetrahydrodipicolinate-N-succinyltransferase, chain A, domain 1 KEGG: 00300+2.3.1.117 GBCGDNIH2_RS03500 95e4da2afed69ed9d2d5d1a172411de4 280 TIGRFAM TIGR00965 dapD: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 6 279 5.9E-122 T 29-03-2018 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 GBCGDNIH2_RS03500 95e4da2afed69ed9d2d5d1a172411de4 280 Gene3D G3DSA:2.160.10.10 90 265 1.9E-34 T 29-03-2018 GBCGDNIH2_RS11205 6aee5a367c96f8e4848d2b295cec67d7 220 SUPERFAMILY SSF53639 3 215 2.16E-63 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal GBCGDNIH2_RS11205 6aee5a367c96f8e4848d2b295cec67d7 220 SMART SM01007 9 186 2.5E-65 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal GBCGDNIH2_RS11205 6aee5a367c96f8e4848d2b295cec67d7 220 Gene3D G3DSA:3.40.225.10 1 216 4.2E-59 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal GBCGDNIH2_RS11205 6aee5a367c96f8e4848d2b295cec67d7 220 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 10 185 1.1E-44 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal GBCGDNIH2_RS04175 f7ed7d1885f2eb393444650f92ee2cd0 784 Gene3D G3DSA:3.40.50.740 111 326 1.1E-39 T 29-03-2018 GBCGDNIH2_RS04175 f7ed7d1885f2eb393444650f92ee2cd0 784 Gene3D G3DSA:3.40.50.740 327 618 7.9E-43 T 29-03-2018 GBCGDNIH2_RS04175 f7ed7d1885f2eb393444650f92ee2cd0 784 SUPERFAMILY SSF50692 639 763 2.26E-14 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain GBCGDNIH2_RS04175 f7ed7d1885f2eb393444650f92ee2cd0 784 TIGRFAM TIGR01701 Fdhalpha-like: oxidoreductase alpha (molybdopterin) subunit 14 758 5.8E-293 T 29-03-2018 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 GBCGDNIH2_RS04175 f7ed7d1885f2eb393444650f92ee2cd0 784 Pfam PF01568 Molydopterin dinucleotide binding domain 646 737 2.5E-7 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 GBCGDNIH2_RS04175 f7ed7d1885f2eb393444650f92ee2cd0 784 Gene3D G3DSA:2.40.40.20 632 767 4.9E-19 T 29-03-2018 GBCGDNIH2_RS04175 f7ed7d1885f2eb393444650f92ee2cd0 784 PIRSF PIRSF000144 1 762 0.0 T 29-03-2018 GBCGDNIH2_RS04175 f7ed7d1885f2eb393444650f92ee2cd0 784 Pfam PF00384 Molybdopterin oxidoreductase 110 414 1.2E-24 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS04175 f7ed7d1885f2eb393444650f92ee2cd0 784 SUPERFAMILY SSF53706 49 638 7.98E-146 T 29-03-2018 GBCGDNIH2_RS01605 3af3aeee327fc26baace1ce8a0cb4037 337 SMART SM00846 3 156 2.1E-81 T 29-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 GBCGDNIH2_RS01605 3af3aeee327fc26baace1ce8a0cb4037 337 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 273 288 3.0E-35 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 GBCGDNIH2_RS01605 3af3aeee327fc26baace1ce8a0cb4037 337 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 233 250 3.0E-35 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 GBCGDNIH2_RS01605 3af3aeee327fc26baace1ce8a0cb4037 337 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 177 193 3.0E-35 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 GBCGDNIH2_RS01605 3af3aeee327fc26baace1ce8a0cb4037 337 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 150 168 3.0E-35 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 GBCGDNIH2_RS01605 3af3aeee327fc26baace1ce8a0cb4037 337 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 114 127 3.0E-35 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 GBCGDNIH2_RS01605 3af3aeee327fc26baace1ce8a0cb4037 337 PIRSF PIRSF000149 1 336 5.7E-126 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 GBCGDNIH2_RS01605 3af3aeee327fc26baace1ce8a0cb4037 337 Gene3D G3DSA:3.40.50.720 1 165 6.9E-68 T 29-03-2018 GBCGDNIH2_RS01605 3af3aeee327fc26baace1ce8a0cb4037 337 Gene3D G3DSA:3.30.360.10 166 319 6.9E-69 T 29-03-2018 GBCGDNIH2_RS01605 3af3aeee327fc26baace1ce8a0cb4037 337 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 161 317 2.2E-65 T 29-03-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 GBCGDNIH2_RS01605 3af3aeee327fc26baace1ce8a0cb4037 337 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 328 4.2E-125 T 29-03-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GBCGDNIH2_RS01605 3af3aeee327fc26baace1ce8a0cb4037 337 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 108 2.8E-30 T 29-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 GBCGDNIH2_RS01605 3af3aeee327fc26baace1ce8a0cb4037 337 SUPERFAMILY SSF55347 156 318 1.07E-69 T 29-03-2018 GBCGDNIH2_RS01605 3af3aeee327fc26baace1ce8a0cb4037 337 SUPERFAMILY SSF51735 3 172 5.72E-53 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS01605 3af3aeee327fc26baace1ce8a0cb4037 337 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 154 161 - T 29-03-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 GBCGDNIH2_RS07040 979b5f160d6a228e1e85a32958cd99b8 524 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 238 467 2.5E-51 T 29-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 GBCGDNIH2_RS07040 979b5f160d6a228e1e85a32958cd99b8 524 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 429 439 - T 29-03-2018 IPR017953 Carbohydrate kinase, predicted, conserved site GBCGDNIH2_RS07040 979b5f160d6a228e1e85a32958cd99b8 524 SUPERFAMILY SSF53613 234 482 5.14E-55 T 29-03-2018 IPR029056 Ribokinase-like GBCGDNIH2_RS07040 979b5f160d6a228e1e85a32958cd99b8 524 Gene3D G3DSA:3.40.1190.20 229 490 3.4E-41 T 29-03-2018 IPR029056 Ribokinase-like GBCGDNIH2_RS07040 979b5f160d6a228e1e85a32958cd99b8 524 Gene3D G3DSA:3.40.50.10260 13 226 3.9E-55 T 29-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 GBCGDNIH2_RS07040 979b5f160d6a228e1e85a32958cd99b8 524 SUPERFAMILY SSF64153 33 253 8.76E-53 T 29-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 GBCGDNIH2_RS07040 979b5f160d6a228e1e85a32958cd99b8 524 Pfam PF01256 Carbohydrate kinase 254 467 1.3E-46 T 29-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 GBCGDNIH2_RS07040 979b5f160d6a228e1e85a32958cd99b8 524 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 231 500 17.567 T 29-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 GBCGDNIH2_RS07040 979b5f160d6a228e1e85a32958cd99b8 524 PIRSF PIRSF017184 13 492 2.0E-99 T 29-03-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 GBCGDNIH2_RS07040 979b5f160d6a228e1e85a32958cd99b8 524 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 21 218 22.396 T 29-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 GBCGDNIH2_RS07040 979b5f160d6a228e1e85a32958cd99b8 524 Pfam PF03853 YjeF-related protein N-terminus 42 197 1.0E-35 T 29-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 GBCGDNIH2_RS07040 979b5f160d6a228e1e85a32958cd99b8 524 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 34 218 2.2E-33 T 29-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 GBCGDNIH2_RS08420 1750c8e10fa2bb9d90cdc6ed7b9ea28f 293 Pfam PF07120 Protein of unknown function (DUF1376) 25 111 5.9E-17 T 29-03-2018 IPR010781 Protein of unknown function DUF1376 GBCGDNIH2_RS06160 a069f24a0245b32c270b572c8b10df6f 651 SUPERFAMILY SSF53448 280 498 6.28E-52 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS06160 a069f24a0245b32c270b572c8b10df6f 651 SUPERFAMILY SSF53448 1 58 2.06E-6 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS06160 a069f24a0245b32c270b572c8b10df6f 651 Gene3D G3DSA:3.90.550.10 1 110 6.1E-4 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS06160 a069f24a0245b32c270b572c8b10df6f 651 Pfam PF00535 Glycosyl transferase family 2 283 452 7.5E-28 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 GBCGDNIH2_RS06160 a069f24a0245b32c270b572c8b10df6f 651 Gene3D G3DSA:3.90.550.10 222 585 1.9E-47 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS06160 a069f24a0245b32c270b572c8b10df6f 651 Pfam PF13704 Glycosyl transferase family 2 11 99 2.3E-12 T 29-03-2018 GBCGDNIH2_RS08920 c5dfc6183f7c1efbcc74bf10358e4d98 247 Gene3D G3DSA:3.30.70.1210 103 239 1.1E-20 T 29-03-2018 GBCGDNIH2_RS08920 c5dfc6183f7c1efbcc74bf10358e4d98 247 Pfam PF08798 CRISPR associated protein 3 239 3.3E-33 T 29-03-2018 IPR010179 CRISPR-associated protein Cse3 GBCGDNIH2_RS08920 c5dfc6183f7c1efbcc74bf10358e4d98 247 SMART SM01101 2 239 9.5E-61 T 29-03-2018 IPR010179 CRISPR-associated protein Cse3 GBCGDNIH2_RS08920 c5dfc6183f7c1efbcc74bf10358e4d98 247 SUPERFAMILY SSF117987 155 239 2.88E-21 T 29-03-2018 GBCGDNIH2_RS08920 c5dfc6183f7c1efbcc74bf10358e4d98 247 SUPERFAMILY SSF117987 104 126 2.88E-21 T 29-03-2018 GBCGDNIH2_RS02800 be07ee75b4849044bb780aa12eb64db4 125 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 61 125 7.0E-22 T 29-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS02800 be07ee75b4849044bb780aa12eb64db4 125 Gene3D G3DSA:1.20.5.710 2 54 2.0E-18 T 29-03-2018 GBCGDNIH2_RS02800 be07ee75b4849044bb780aa12eb64db4 125 Gene3D G3DSA:3.30.1390.10 55 125 5.0E-32 T 29-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like GBCGDNIH2_RS02800 be07ee75b4849044bb780aa12eb64db4 125 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 5 50 1.3E-19 T 29-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS02800 be07ee75b4849044bb780aa12eb64db4 125 SUPERFAMILY SSF48300 3 61 3.4E-16 T 29-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS02800 be07ee75b4849044bb780aa12eb64db4 125 SUPERFAMILY SSF54736 54 125 3.49E-25 T 29-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like GBCGDNIH2_RS02800 be07ee75b4849044bb780aa12eb64db4 125 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 125 1.4E-48 T 29-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS02800 be07ee75b4849044bb780aa12eb64db4 125 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 59 125 1.3E-30 T 29-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS02800 be07ee75b4849044bb780aa12eb64db4 125 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 1 125 24.86 T 29-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS03220 43fc3a4c3a66da36ca19aa56ea50b75f 628 SMART SM00327 416 625 2.7E-4 T 29-03-2018 IPR002035 von Willebrand factor, type A GBCGDNIH2_RS03220 43fc3a4c3a66da36ca19aa56ea50b75f 628 Gene3D G3DSA:3.40.50.410 389 626 2.3E-18 T 29-03-2018 IPR002035 von Willebrand factor, type A GBCGDNIH2_RS03220 43fc3a4c3a66da36ca19aa56ea50b75f 628 Pfam PF11775 Cobalamin biosynthesis protein CobT VWA domain 405 622 1.1E-108 T 29-03-2018 IPR025861 Cobalamin biosynthesis protein CobT VWA domain KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 GBCGDNIH2_RS03220 43fc3a4c3a66da36ca19aa56ea50b75f 628 SUPERFAMILY SSF53300 419 615 3.4E-16 T 29-03-2018 IPR002035 von Willebrand factor, type A GBCGDNIH2_RS03220 43fc3a4c3a66da36ca19aa56ea50b75f 628 Pfam PF06213 Cobalamin biosynthesis protein CobT 21 296 8.9E-88 T 29-03-2018 IPR006538 Cobalt chelatase, CobT subunit GO:0009236 KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 GBCGDNIH2_RS03220 43fc3a4c3a66da36ca19aa56ea50b75f 628 PIRSF PIRSF031715 12 628 1.0E-249 T 29-03-2018 IPR006538 Cobalt chelatase, CobT subunit GO:0009236 KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 GBCGDNIH2_RS03220 43fc3a4c3a66da36ca19aa56ea50b75f 628 TIGRFAM TIGR01651 CobT: cobaltochelatase, CobT subunit 24 623 5.5E-248 T 29-03-2018 IPR006538 Cobalt chelatase, CobT subunit GO:0009236 KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 GBCGDNIH2_RS03985 50296e7552ff634af6b5c6310893b19d 383 Gene3D G3DSA:3.30.470.20 112 373 3.3E-10 T 29-03-2018 GBCGDNIH2_RS03985 50296e7552ff634af6b5c6310893b19d 383 SUPERFAMILY SSF56059 112 278 5.21E-11 T 29-03-2018 GBCGDNIH2_RS03985 50296e7552ff634af6b5c6310893b19d 383 Pfam PF02655 ATP-grasp domain 126 277 6.1E-8 T 29-03-2018 IPR003806 ATP-grasp fold, DUF201-type GO:0005524|GO:0046872 GBCGDNIH2_RS03985 50296e7552ff634af6b5c6310893b19d 383 PIRSF PIRSF016817 2 383 2.0E-68 T 29-03-2018 IPR016677 Uncharacterised conserved protein UCP016817, ATP-dependent carboligase GBCGDNIH2_RS02205 3ea8fe039e15fddfd22e2f9cba1f6a41 481 Pfam PF01225 Mur ligase family, catalytic domain 10 108 3.7E-30 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 GBCGDNIH2_RS02205 3ea8fe039e15fddfd22e2f9cba1f6a41 481 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 8 466 40.067 T 29-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GBCGDNIH2_RS02205 3ea8fe039e15fddfd22e2f9cba1f6a41 481 Gene3D G3DSA:3.90.190.20 320 466 1.2E-35 T 29-03-2018 GBCGDNIH2_RS02205 3ea8fe039e15fddfd22e2f9cba1f6a41 481 Gene3D G3DSA:3.40.50.720 11 96 2.1E-16 T 29-03-2018 GBCGDNIH2_RS02205 3ea8fe039e15fddfd22e2f9cba1f6a41 481 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 11 459 1.4E-156 T 29-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GBCGDNIH2_RS02205 3ea8fe039e15fddfd22e2f9cba1f6a41 481 SUPERFAMILY SSF51984 10 95 8.89E-28 T 29-03-2018 GBCGDNIH2_RS02205 3ea8fe039e15fddfd22e2f9cba1f6a41 481 SUPERFAMILY SSF53244 318 462 5.72E-45 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 GBCGDNIH2_RS02205 3ea8fe039e15fddfd22e2f9cba1f6a41 481 Pfam PF08245 Mur ligase middle domain 113 299 5.4E-28 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 GBCGDNIH2_RS02205 3ea8fe039e15fddfd22e2f9cba1f6a41 481 Pfam PF02875 Mur ligase family, glutamate ligase domain 319 404 5.5E-18 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 GBCGDNIH2_RS02205 3ea8fe039e15fddfd22e2f9cba1f6a41 481 Gene3D G3DSA:3.40.1190.10 97 319 2.1E-49 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 GBCGDNIH2_RS02205 3ea8fe039e15fddfd22e2f9cba1f6a41 481 SUPERFAMILY SSF53623 94 317 6.67E-66 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 GBCGDNIH2_RS00360 c62b8222c012332007fe2529e44684c7 424 Gene3D G3DSA:3.40.50.620 102 266 5.0E-21 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GBCGDNIH2_RS00360 c62b8222c012332007fe2529e44684c7 424 SMART SM00893 103 278 2.1E-11 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 GBCGDNIH2_RS00360 c62b8222c012332007fe2529e44684c7 424 Pfam PF01012 Electron transfer flavoprotein domain 109 240 1.0E-19 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 GBCGDNIH2_RS00360 c62b8222c012332007fe2529e44684c7 424 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 285 362 7.0E-23 T 29-03-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 GBCGDNIH2_RS00360 c62b8222c012332007fe2529e44684c7 424 Gene3D G3DSA:3.40.50.1220 280 407 2.3E-36 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain GBCGDNIH2_RS00360 c62b8222c012332007fe2529e44684c7 424 SUPERFAMILY SSF52402 103 235 2.09E-20 T 29-03-2018 GBCGDNIH2_RS00360 c62b8222c012332007fe2529e44684c7 424 SUPERFAMILY SSF52467 285 400 4.71E-31 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain GBCGDNIH2_RS10785 ea1e7bb91926c054bd1238f1861f5eb4 317 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 147 310 1.9E-28 T 29-03-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 GBCGDNIH2_RS10785 ea1e7bb91926c054bd1238f1861f5eb4 317 PIRSF PIRSF000102 1 317 3.3E-102 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 GBCGDNIH2_RS10785 ea1e7bb91926c054bd1238f1861f5eb4 317 SUPERFAMILY SSF51735 5 144 5.15E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS10785 ea1e7bb91926c054bd1238f1861f5eb4 317 TIGRFAM TIGR01763 MalateDH_bact: malate dehydrogenase, NAD-dependent 3 309 1.7E-126 T 29-03-2018 IPR011275 Malate dehydrogenase, type 3 GO:0016616|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 GBCGDNIH2_RS10785 ea1e7bb91926c054bd1238f1861f5eb4 317 Gene3D G3DSA:3.90.110.10 146 317 7.3E-52 T 29-03-2018 GBCGDNIH2_RS10785 ea1e7bb91926c054bd1238f1861f5eb4 317 SUPERFAMILY SSF56327 144 310 3.03E-56 T 29-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 GBCGDNIH2_RS10785 ea1e7bb91926c054bd1238f1861f5eb4 317 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 5 143 1.9E-37 T 29-03-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 GBCGDNIH2_RS10785 ea1e7bb91926c054bd1238f1861f5eb4 317 Gene3D G3DSA:3.40.50.720 5 145 5.5E-38 T 29-03-2018 GBCGDNIH2_RS10785 ea1e7bb91926c054bd1238f1861f5eb4 317 PRINTS PR00086 L-lactate dehydrogenase signature 171 184 1.4E-27 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 GBCGDNIH2_RS10785 ea1e7bb91926c054bd1238f1861f5eb4 317 PRINTS PR00086 L-lactate dehydrogenase signature 5 29 1.4E-27 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 GBCGDNIH2_RS10785 ea1e7bb91926c054bd1238f1861f5eb4 317 PRINTS PR00086 L-lactate dehydrogenase signature 117 137 1.4E-27 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 GBCGDNIH2_RS10785 ea1e7bb91926c054bd1238f1861f5eb4 317 PRINTS PR00086 L-lactate dehydrogenase signature 29 53 1.4E-27 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 GBCGDNIH2_RS10785 ea1e7bb91926c054bd1238f1861f5eb4 317 PRINTS PR00086 L-lactate dehydrogenase signature 141 159 1.4E-27 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 GBCGDNIH2_RS10785 ea1e7bb91926c054bd1238f1861f5eb4 317 Hamap MF_00487 Malate dehydrogenase [mdh]. 3 313 45.418 T 29-03-2018 IPR011275 Malate dehydrogenase, type 3 GO:0016616|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 GBCGDNIH2_RS04540 210d0d78cf1abfcbdb73ac263e24d915 454 Gene3D G3DSA:3.30.70.20 6 34 0.028 T 29-03-2018 GBCGDNIH2_RS04540 210d0d78cf1abfcbdb73ac263e24d915 454 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 25 36 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site GBCGDNIH2_RS04540 210d0d78cf1abfcbdb73ac263e24d915 454 Gene3D G3DSA:3.30.70.20 78 376 1.5E-4 T 29-03-2018 GBCGDNIH2_RS04540 210d0d78cf1abfcbdb73ac263e24d915 454 PIRSF PIRSF000139 5 436 1.0E-122 T 29-03-2018 GBCGDNIH2_RS04540 210d0d78cf1abfcbdb73ac263e24d915 454 Pfam PF02754 Cysteine-rich domain 331 414 1.1E-9 T 29-03-2018 IPR004017 Cysteine-rich domain GBCGDNIH2_RS04540 210d0d78cf1abfcbdb73ac263e24d915 454 Pfam PF02754 Cysteine-rich domain 197 282 1.6E-12 T 29-03-2018 IPR004017 Cysteine-rich domain GBCGDNIH2_RS04540 210d0d78cf1abfcbdb73ac263e24d915 454 Pfam PF12838 4Fe-4S dicluster domain 24 90 1.1E-11 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain GBCGDNIH2_RS04540 210d0d78cf1abfcbdb73ac263e24d915 454 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 76 87 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site GBCGDNIH2_RS04540 210d0d78cf1abfcbdb73ac263e24d915 454 SUPERFAMILY SSF46548 21 103 5.75E-21 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 GBCGDNIH2_RS04540 210d0d78cf1abfcbdb73ac263e24d915 454 Gene3D G3DSA:3.30.70.20 35 77 9.3E-8 T 29-03-2018 GBCGDNIH2_RS04485 19a15b83a15aea9445f42fe0e8048b61 563 Gene3D G3DSA:3.40.50.300 331 562 5.7E-57 T 29-03-2018 GBCGDNIH2_RS04485 19a15b83a15aea9445f42fe0e8048b61 563 SUPERFAMILY SSF90123 14 316 2.88E-33 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 GBCGDNIH2_RS04485 19a15b83a15aea9445f42fe0e8048b61 563 Pfam PF00005 ABC transporter 362 510 8.2E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GBCGDNIH2_RS04485 19a15b83a15aea9445f42fe0e8048b61 563 Pfam PF00664 ABC transporter transmembrane region 23 268 7.0E-10 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 GBCGDNIH2_RS04485 19a15b83a15aea9445f42fe0e8048b61 563 Gene3D G3DSA:1.20.1560.10 6 314 7.5E-23 T 29-03-2018 GBCGDNIH2_RS04485 19a15b83a15aea9445f42fe0e8048b61 563 SUPERFAMILY SSF52540 340 559 7.99E-66 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS04485 19a15b83a15aea9445f42fe0e8048b61 563 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 14 541 1.0E-119 T 29-03-2018 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0006810|GO:0016021|GO:0042626 GBCGDNIH2_RS04485 19a15b83a15aea9445f42fe0e8048b61 563 SMART SM00382 371 563 2.0E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS10720 e7e0bba6847a5cacaf13ae3533b0463f 511 Gene3D G3DSA:3.40.50.300 84 373 1.6E-121 T 29-03-2018 GBCGDNIH2_RS10720 e7e0bba6847a5cacaf13ae3533b0463f 511 SUPERFAMILY SSF50615 10 95 6.28E-28 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 GBCGDNIH2_RS10720 e7e0bba6847a5cacaf13ae3533b0463f 511 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 25 92 3.9E-18 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 GBCGDNIH2_RS10720 e7e0bba6847a5cacaf13ae3533b0463f 511 Gene3D G3DSA:1.20.150.20 382 509 7.8E-50 T 29-03-2018 GBCGDNIH2_RS10720 e7e0bba6847a5cacaf13ae3533b0463f 511 SUPERFAMILY SSF47917 381 509 4.71E-46 T 29-03-2018 GBCGDNIH2_RS10720 e7e0bba6847a5cacaf13ae3533b0463f 511 PIRSF PIRSF039088 1 511 1.3E-284 T 29-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 GBCGDNIH2_RS10720 e7e0bba6847a5cacaf13ae3533b0463f 511 Gene3D G3DSA:2.40.30.20 3 83 1.5E-40 T 29-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 GBCGDNIH2_RS10720 e7e0bba6847a5cacaf13ae3533b0463f 511 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 150 373 5.9E-71 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 GBCGDNIH2_RS10720 e7e0bba6847a5cacaf13ae3533b0463f 511 SUPERFAMILY SSF52540 97 379 1.91E-99 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS10720 e7e0bba6847a5cacaf13ae3533b0463f 511 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 510 50.821 T 29-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 GBCGDNIH2_RS10720 e7e0bba6847a5cacaf13ae3533b0463f 511 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 380 504 2.7E-47 T 29-03-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 GBCGDNIH2_RS10720 e7e0bba6847a5cacaf13ae3533b0463f 511 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 364 373 - T 29-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 GBCGDNIH2_RS10720 e7e0bba6847a5cacaf13ae3533b0463f 511 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 3 510 8.7E-250 T 29-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 GBCGDNIH2_RS02295 d75977427ef4abc02da608def8142d76 397 PIRSF PIRSF006004 35 397 4.9E-134 T 29-03-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 GBCGDNIH2_RS02295 d75977427ef4abc02da608def8142d76 397 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 41 392 72.127 T 29-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 GBCGDNIH2_RS02295 d75977427ef4abc02da608def8142d76 397 Pfam PF04055 Radical SAM superfamily 147 321 3.1E-14 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 GBCGDNIH2_RS02295 d75977427ef4abc02da608def8142d76 397 SUPERFAMILY SSF102114 136 368 1.83E-13 T 29-03-2018 GBCGDNIH2_RS02295 d75977427ef4abc02da608def8142d76 397 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 39 394 5.8E-116 T 29-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 GBCGDNIH2_RS02295 d75977427ef4abc02da608def8142d76 397 Gene3D G3DSA:3.20.20.70 48 385 2.8E-38 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS07825 36bfbf8e7c13cde255fb1d53ff70b7a1 298 Pfam PF04085 rod shape-determining protein MreC 148 270 1.8E-22 T 29-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 GBCGDNIH2_RS07825 36bfbf8e7c13cde255fb1d53ff70b7a1 298 PIRSF PIRSF038471 5 272 5.9E-48 T 29-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 GBCGDNIH2_RS04190 422d758f6f335fe329c78664ce10889f 242 Gene3D G3DSA:1.10.10.10 1 68 1.4E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS04190 422d758f6f335fe329c78664ce10889f 242 SUPERFAMILY SSF51306 118 240 6.63E-32 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C GBCGDNIH2_RS04190 422d758f6f335fe329c78664ce10889f 242 TIGRFAM TIGR00498 lexA: repressor LexA 110 241 5.3E-36 T 29-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 GBCGDNIH2_RS04190 422d758f6f335fe329c78664ce10889f 242 Pfam PF00717 Peptidase S24-like 158 222 3.7E-11 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C GBCGDNIH2_RS04190 422d758f6f335fe329c78664ce10889f 242 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 166 177 3.5E-10 T 29-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 GBCGDNIH2_RS04190 422d758f6f335fe329c78664ce10889f 242 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 155 165 3.5E-10 T 29-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 GBCGDNIH2_RS04190 422d758f6f335fe329c78664ce10889f 242 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 195 207 3.5E-10 T 29-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 GBCGDNIH2_RS04190 422d758f6f335fe329c78664ce10889f 242 SUPERFAMILY SSF46785 2 68 1.92E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS04190 422d758f6f335fe329c78664ce10889f 242 Pfam PF01726 LexA DNA binding domain 2 63 2.8E-14 T 29-03-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 GBCGDNIH2_RS04190 422d758f6f335fe329c78664ce10889f 242 Gene3D G3DSA:2.10.109.10 124 242 1.7E-21 T 29-03-2018 GBCGDNIH2_RS04190 422d758f6f335fe329c78664ce10889f 242 Hamap MF_00015 LexA repressor [lexA]. 1 242 32.42 T 29-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 GBCGDNIH2_RS03135 79aaabe8f3af5d8b3902eba60b58b264 100 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 58 1.6E-24 T 29-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS03135 79aaabe8f3af5d8b3902eba60b58b264 100 Pfam PF00830 Ribosomal L28 family 3 61 1.3E-24 T 29-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS03135 79aaabe8f3af5d8b3902eba60b58b264 100 SUPERFAMILY SSF143800 1 80 6.08E-27 T 29-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS03135 79aaabe8f3af5d8b3902eba60b58b264 100 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 68 21.439 T 29-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS03135 79aaabe8f3af5d8b3902eba60b58b264 100 Gene3D G3DSA:2.30.170.40 2 76 7.2E-29 T 29-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS00815 5a28397445d59a1b2c29896919890406 525 SMART SM00382 221 352 4.2E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS00815 5a28397445d59a1b2c29896919890406 525 Gene3D G3DSA:1.10.8.60 357 426 3.3E-25 T 29-03-2018 GBCGDNIH2_RS00815 5a28397445d59a1b2c29896919890406 525 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 46 523 4.8E-159 T 29-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 GBCGDNIH2_RS00815 5a28397445d59a1b2c29896919890406 525 Gene3D G3DSA:3.40.50.300 185 354 2.2E-16 T 29-03-2018 GBCGDNIH2_RS00815 5a28397445d59a1b2c29896919890406 525 SMART SM00760 433 502 1.4E-37 T 29-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 GBCGDNIH2_RS00815 5a28397445d59a1b2c29896919890406 525 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 43 524 31.182 T 29-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 GBCGDNIH2_RS00815 5a28397445d59a1b2c29896919890406 525 ProSitePatterns PS01008 DnaA protein signature. 483 502 - T 29-03-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 GBCGDNIH2_RS00815 5a28397445d59a1b2c29896919890406 525 SUPERFAMILY SSF52540 189 401 1.22E-35 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS00815 5a28397445d59a1b2c29896919890406 525 Gene3D G3DSA:1.10.1750.10 427 524 1.2E-32 T 29-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 GBCGDNIH2_RS00815 5a28397445d59a1b2c29896919890406 525 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 483 502 4.4E-44 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like GBCGDNIH2_RS00815 5a28397445d59a1b2c29896919890406 525 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 321 348 4.4E-44 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like GBCGDNIH2_RS00815 5a28397445d59a1b2c29896919890406 525 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 287 301 4.4E-44 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like GBCGDNIH2_RS00815 5a28397445d59a1b2c29896919890406 525 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 222 242 4.4E-44 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like GBCGDNIH2_RS00815 5a28397445d59a1b2c29896919890406 525 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 255 269 4.4E-44 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like GBCGDNIH2_RS00815 5a28397445d59a1b2c29896919890406 525 Pfam PF00308 Bacterial dnaA protein 188 406 1.5E-84 T 29-03-2018 IPR013317 Chromosomal replication initiator protein DnaA GBCGDNIH2_RS00815 5a28397445d59a1b2c29896919890406 525 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 434 502 1.4E-27 T 29-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 GBCGDNIH2_RS00815 5a28397445d59a1b2c29896919890406 525 Pfam PF11638 DnaA N-terminal domain 44 105 1.8E-21 T 29-03-2018 IPR024633 DnaA N-terminal domain GBCGDNIH2_RS00815 5a28397445d59a1b2c29896919890406 525 SUPERFAMILY SSF48295 420 524 2.33E-36 T 29-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 GBCGDNIH2_RS10640 2e60b64098f59122f8a9ed34834f73c6 176 Gene3D G3DSA:2.30.30.30 118 176 1.3E-20 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 GBCGDNIH2_RS10640 2e60b64098f59122f8a9ed34834f73c6 176 SUPERFAMILY SSF50104 121 176 1.05E-18 T 29-03-2018 IPR008991 Translation protein SH3-like domain GBCGDNIH2_RS10640 2e60b64098f59122f8a9ed34834f73c6 176 ProSitePatterns PS01014 Transcription termination factor nusG signature. 159 168 - T 29-03-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site GBCGDNIH2_RS10640 2e60b64098f59122f8a9ed34834f73c6 176 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 2 176 24.942 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 GBCGDNIH2_RS10640 2e60b64098f59122f8a9ed34834f73c6 176 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 5 176 6.7E-69 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 GBCGDNIH2_RS10640 2e60b64098f59122f8a9ed34834f73c6 176 SMART SM00739 122 149 2.2E-4 T 29-03-2018 IPR005824 KOW GBCGDNIH2_RS10640 2e60b64098f59122f8a9ed34834f73c6 176 Gene3D G3DSA:3.30.70.940 2 114 5.6E-41 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 GBCGDNIH2_RS10640 2e60b64098f59122f8a9ed34834f73c6 176 SMART SM00738 2 110 7.8E-47 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 GBCGDNIH2_RS10640 2e60b64098f59122f8a9ed34834f73c6 176 Pfam PF00467 KOW motif 125 155 7.4E-5 T 29-03-2018 IPR005824 KOW GBCGDNIH2_RS10640 2e60b64098f59122f8a9ed34834f73c6 176 Pfam PF02357 Transcription termination factor nusG 3 107 5.6E-27 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 GBCGDNIH2_RS10640 2e60b64098f59122f8a9ed34834f73c6 176 SUPERFAMILY SSF82679 3 112 8.89E-38 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 GBCGDNIH2_RS10640 2e60b64098f59122f8a9ed34834f73c6 176 PRINTS PR00338 Transcription termination factor NUSG signature 152 168 1.8E-20 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 GBCGDNIH2_RS10640 2e60b64098f59122f8a9ed34834f73c6 176 PRINTS PR00338 Transcription termination factor NUSG signature 57 69 1.8E-20 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 GBCGDNIH2_RS10640 2e60b64098f59122f8a9ed34834f73c6 176 PRINTS PR00338 Transcription termination factor NUSG signature 134 149 1.8E-20 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 GBCGDNIH2_RS06690 947a2c9440b41b2a698f0ed042bb5817 115 PRINTS PR00189 Transthyretin signature 3 23 3.6E-8 T 29-03-2018 IPR000895 Transthyretin/hydroxyisourate hydrolase Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 GBCGDNIH2_RS06690 947a2c9440b41b2a698f0ed042bb5817 115 PRINTS PR00189 Transthyretin signature 93 115 3.6E-8 T 29-03-2018 IPR000895 Transthyretin/hydroxyisourate hydrolase Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 GBCGDNIH2_RS06690 947a2c9440b41b2a698f0ed042bb5817 115 ProSitePatterns PS00769 Transthyretin signature 2. 98 110 - T 29-03-2018 IPR023419 Transthyretin, conserved site Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 GBCGDNIH2_RS06690 947a2c9440b41b2a698f0ed042bb5817 115 SUPERFAMILY SSF49472 1 115 1.31E-39 T 29-03-2018 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 GBCGDNIH2_RS06690 947a2c9440b41b2a698f0ed042bb5817 115 Pfam PF00576 HIUase/Transthyretin family 4 114 1.6E-33 T 29-03-2018 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 GBCGDNIH2_RS06690 947a2c9440b41b2a698f0ed042bb5817 115 ProSitePatterns PS00768 Transthyretin signature 1. 7 22 - T 29-03-2018 IPR023418 Transthyretin, thyroxine binding site Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 GBCGDNIH2_RS06690 947a2c9440b41b2a698f0ed042bb5817 115 Gene3D G3DSA:2.60.40.180 1 115 4.0E-36 T 29-03-2018 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 GBCGDNIH2_RS06690 947a2c9440b41b2a698f0ed042bb5817 115 TIGRFAM TIGR02962 hdxy_isourate: hydroxyisourate hydrolase 2 115 8.1E-38 T 29-03-2018 IPR014306 Hydroxyisourate hydrolase GO:0006144|GO:0033971 KEGG: 00230+3.5.2.17|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 GBCGDNIH2_RS00590 add8a179597f04f088fdb0041de1c757 143 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 40 135 1.4E-22 T 29-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 GBCGDNIH2_RS00590 add8a179597f04f088fdb0041de1c757 143 Gene3D G3DSA:3.40.390.30 7 143 1.2E-31 T 29-03-2018 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 GBCGDNIH2_RS00590 add8a179597f04f088fdb0041de1c757 143 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 1 138 17.883 T 29-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 GBCGDNIH2_RS00590 add8a179597f04f088fdb0041de1c757 143 SUPERFAMILY SSF55486 30 140 5.86E-31 T 29-03-2018 GBCGDNIH2_RS00590 add8a179597f04f088fdb0041de1c757 143 Pfam PF02130 Uncharacterized protein family UPF0054 35 133 1.6E-24 T 29-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 GBCGDNIH2_RS03000 e508523b6d2f805846a96ddc31a494c4 239 Gene3D G3DSA:3.30.930.10 19 233 4.3E-54 T 29-03-2018 GBCGDNIH2_RS03000 e508523b6d2f805846a96ddc31a494c4 239 Pfam PF03099 Biotin/lipoate A/B protein ligase family 88 188 4.0E-5 T 29-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 GBCGDNIH2_RS03000 e508523b6d2f805846a96ddc31a494c4 239 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 54 215 7.6E-46 T 29-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 GBCGDNIH2_RS03000 e508523b6d2f805846a96ddc31a494c4 239 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 91 106 - T 29-03-2018 IPR020605 Octanoyltransferase, conserved site GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 GBCGDNIH2_RS03000 e508523b6d2f805846a96ddc31a494c4 239 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 96 153 2.0E-15 T 29-03-2018 GBCGDNIH2_RS03000 e508523b6d2f805846a96ddc31a494c4 239 SUPERFAMILY SSF55681 27 233 1.49E-59 T 29-03-2018 GBCGDNIH2_RS03000 e508523b6d2f805846a96ddc31a494c4 239 Hamap MF_00013 Octanoyltransferase [lipB]. 24 235 33.154 T 29-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 GBCGDNIH2_RS03000 e508523b6d2f805846a96ddc31a494c4 239 PIRSF PIRSF016262 21 236 6.1E-52 T 29-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 GBCGDNIH2_RS01730 cf853fbd6c19f3098c625a72d2e03114 171 Gene3D G3DSA:3.40.50.2020 1 167 2.8E-43 T 29-03-2018 GBCGDNIH2_RS01730 cf853fbd6c19f3098c625a72d2e03114 171 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 3 169 34.638 T 29-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 GBCGDNIH2_RS01730 cf853fbd6c19f3098c625a72d2e03114 171 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 3 167 2.2E-60 T 29-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 GBCGDNIH2_RS01730 cf853fbd6c19f3098c625a72d2e03114 171 Pfam PF00156 Phosphoribosyl transferase domain 46 149 7.9E-18 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 GBCGDNIH2_RS01730 cf853fbd6c19f3098c625a72d2e03114 171 SUPERFAMILY SSF53271 2 160 2.62E-49 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like GBCGDNIH2_RS12095 4699f675f45a8589a65843232fd7ea68 597 ProSitePatterns PS00211 ABC transporters family signature. 489 503 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GBCGDNIH2_RS12095 4699f675f45a8589a65843232fd7ea68 597 SUPERFAMILY SSF52540 341 588 4.35E-90 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS12095 4699f675f45a8589a65843232fd7ea68 597 Pfam PF00664 ABC transporter transmembrane region 35 298 1.1E-13 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 GBCGDNIH2_RS12095 4699f675f45a8589a65843232fd7ea68 597 Pfam PF00005 ABC transporter 369 517 5.9E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GBCGDNIH2_RS12095 4699f675f45a8589a65843232fd7ea68 597 SMART SM00382 377 563 5.9E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS12095 4699f675f45a8589a65843232fd7ea68 597 Gene3D G3DSA:3.40.50.300 344 592 3.3E-76 T 29-03-2018 GBCGDNIH2_RS12095 4699f675f45a8589a65843232fd7ea68 597 SUPERFAMILY SSF90123 18 336 2.09E-44 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 GBCGDNIH2_RS12095 4699f675f45a8589a65843232fd7ea68 597 Gene3D G3DSA:1.20.1560.10 10 341 1.8E-32 T 29-03-2018 GBCGDNIH2_RS10235 df08fa2d4e17f4e6429e3677c44be455 70 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 7 70 1.8E-21 T 29-03-2018 IPR010035 ThiS, thiamine-biosynthesis GBCGDNIH2_RS10235 df08fa2d4e17f4e6429e3677c44be455 70 Gene3D G3DSA:3.10.20.30 6 70 1.8E-20 T 29-03-2018 IPR012675 Beta-grasp domain GBCGDNIH2_RS10235 df08fa2d4e17f4e6429e3677c44be455 70 Pfam PF02597 ThiS family 15 70 8.5E-13 T 29-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 GBCGDNIH2_RS10235 df08fa2d4e17f4e6429e3677c44be455 70 SUPERFAMILY SSF54285 7 69 6.87E-17 T 29-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp GBCGDNIH2_RS02910 1546dcbc59776ce3fa826c364898a7c4 177 Gene3D G3DSA:3.90.930.12 83 177 2.1E-37 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02910 1546dcbc59776ce3fa826c364898a7c4 177 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 176 1.1E-70 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 GBCGDNIH2_RS02910 1546dcbc59776ce3fa826c364898a7c4 177 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 35.759 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 GBCGDNIH2_RS02910 1546dcbc59776ce3fa826c364898a7c4 177 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 154 162 - T 29-03-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS02910 1546dcbc59776ce3fa826c364898a7c4 177 PIRSF PIRSF002162 1 177 9.9E-47 T 29-03-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02910 1546dcbc59776ce3fa826c364898a7c4 177 SUPERFAMILY SSF56053 1 82 3.66E-25 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02910 1546dcbc59776ce3fa826c364898a7c4 177 SUPERFAMILY SSF56053 83 177 1.61E-34 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02910 1546dcbc59776ce3fa826c364898a7c4 177 PRINTS PR00059 Ribosomal protein L6 signature 71 96 9.6E-31 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 GBCGDNIH2_RS02910 1546dcbc59776ce3fa826c364898a7c4 177 PRINTS PR00059 Ribosomal protein L6 signature 99 115 9.6E-31 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 GBCGDNIH2_RS02910 1546dcbc59776ce3fa826c364898a7c4 177 PRINTS PR00059 Ribosomal protein L6 signature 141 162 9.6E-31 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 GBCGDNIH2_RS02910 1546dcbc59776ce3fa826c364898a7c4 177 Gene3D G3DSA:3.90.930.12 2 82 1.8E-28 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02910 1546dcbc59776ce3fa826c364898a7c4 177 Pfam PF00347 Ribosomal protein L6 91 164 2.7E-16 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02910 1546dcbc59776ce3fa826c364898a7c4 177 Pfam PF00347 Ribosomal protein L6 11 82 7.5E-18 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02840 2397baf545795422553c1aa68a0172be 215 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 9 205 29.543 T 29-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS02840 2397baf545795422553c1aa68a0172be 215 SUPERFAMILY SSF52166 1 204 1.7E-64 T 29-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 GBCGDNIH2_RS02840 2397baf545795422553c1aa68a0172be 215 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 17 201 2.8E-63 T 29-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS02840 2397baf545795422553c1aa68a0172be 215 Pfam PF00573 Ribosomal protein L4/L1 family 17 202 5.8E-57 T 29-03-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 GBCGDNIH2_RS02840 2397baf545795422553c1aa68a0172be 215 Gene3D G3DSA:3.40.1370.10 134 203 7.5E-8 T 29-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 GBCGDNIH2_RS02840 2397baf545795422553c1aa68a0172be 215 Gene3D G3DSA:3.40.1370.10 1 133 1.8E-47 T 29-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 GBCGDNIH2_RS11475 59bf4969f2911a90611ae1908d4dd6ed 154 Pfam PF01250 Ribosomal protein S6 4 92 2.2E-29 T 29-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS11475 59bf4969f2911a90611ae1908d4dd6ed 154 Gene3D G3DSA:3.30.70.60 1 99 3.2E-31 T 29-03-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 GBCGDNIH2_RS11475 59bf4969f2911a90611ae1908d4dd6ed 154 TIGRFAM TIGR00166 S6: ribosomal protein bS6 2 94 7.4E-23 T 29-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS11475 59bf4969f2911a90611ae1908d4dd6ed 154 SUPERFAMILY SSF54995 1 102 6.93E-33 T 29-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS11475 59bf4969f2911a90611ae1908d4dd6ed 154 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 95 20.936 T 29-03-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 GBCGDNIH2_RS07030 6e1b3679a5bc6b98b271207b24864653 444 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 159 237 1.4E-10 T 29-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GBCGDNIH2_RS07030 6e1b3679a5bc6b98b271207b24864653 444 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 262 420 2.9E-38 T 29-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 GBCGDNIH2_RS07030 6e1b3679a5bc6b98b271207b24864653 444 TIGRFAM TIGR00115 tig: trigger factor 11 419 8.9E-124 T 29-03-2018 IPR005215 Trigger factor GO:0015031 GBCGDNIH2_RS07030 6e1b3679a5bc6b98b271207b24864653 444 Pfam PF05697 Bacterial trigger factor protein (TF) 1 143 3.0E-36 T 29-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 GBCGDNIH2_RS07030 6e1b3679a5bc6b98b271207b24864653 444 Gene3D G3DSA:3.10.50.40 159 228 2.6E-11 T 29-03-2018 GBCGDNIH2_RS07030 6e1b3679a5bc6b98b271207b24864653 444 Gene3D G3DSA:3.30.70.1050 1 118 3.6E-32 T 29-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 GBCGDNIH2_RS07030 6e1b3679a5bc6b98b271207b24864653 444 Gene3D G3DSA:1.10.3120.10 229 396 5.7E-42 T 29-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 GBCGDNIH2_RS07030 6e1b3679a5bc6b98b271207b24864653 444 Hamap MF_00303 Trigger factor [tig]. 1 425 20.357 T 29-03-2018 IPR005215 Trigger factor GO:0015031 GBCGDNIH2_RS07030 6e1b3679a5bc6b98b271207b24864653 444 PIRSF PIRSF003095 1 440 3.0E-117 T 29-03-2018 IPR005215 Trigger factor GO:0015031 GBCGDNIH2_RS07030 6e1b3679a5bc6b98b271207b24864653 444 SUPERFAMILY SSF109998 250 434 7.26E-44 T 29-03-2018 IPR027304 Trigger factor/SurA domain GBCGDNIH2_RS07030 6e1b3679a5bc6b98b271207b24864653 444 SUPERFAMILY SSF54534 88 243 1.36E-26 T 29-03-2018 GBCGDNIH2_RS07030 6e1b3679a5bc6b98b271207b24864653 444 SUPERFAMILY SSF102735 1 130 3.01E-35 T 29-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 GBCGDNIH2_RS02635 d906b3ed47bd525953a67793aee6dc74 485 Pfam PF01467 Cytidylyltransferase-like 355 437 1.6E-9 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 GBCGDNIH2_RS02635 d906b3ed47bd525953a67793aee6dc74 485 TIGRFAM TIGR02199 rfaE_dom_II: bifunctional protein RfaE, domain II 341 482 3.9E-55 T 29-03-2018 IPR011914 RfaE bifunctional protein, domain II GO:0005975|GO:0016773|GO:0016779 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.7.70+2.7.1.167 GBCGDNIH2_RS02635 d906b3ed47bd525953a67793aee6dc74 485 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 352 416 3.9E-13 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 GBCGDNIH2_RS02635 d906b3ed47bd525953a67793aee6dc74 485 SUPERFAMILY SSF52374 352 481 2.73E-19 T 29-03-2018 GBCGDNIH2_RS02635 d906b3ed47bd525953a67793aee6dc74 485 TIGRFAM TIGR02198 rfaE_dom_I: bifunctional protein RfaE, domain I 3 318 2.3E-111 T 29-03-2018 IPR011913 RfaE bifunctional protein, domain I GO:0005975|GO:0016773|GO:0016779 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.7.70+2.7.1.167 GBCGDNIH2_RS02635 d906b3ed47bd525953a67793aee6dc74 485 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 46 69 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 GBCGDNIH2_RS02635 d906b3ed47bd525953a67793aee6dc74 485 Gene3D G3DSA:3.40.50.620 334 484 3.2E-19 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GBCGDNIH2_RS02635 d906b3ed47bd525953a67793aee6dc74 485 SUPERFAMILY SSF53613 7 321 1.22E-48 T 29-03-2018 IPR029056 Ribokinase-like GBCGDNIH2_RS02635 d906b3ed47bd525953a67793aee6dc74 485 Gene3D G3DSA:3.40.1190.20 1 330 9.1E-43 T 29-03-2018 IPR029056 Ribokinase-like GBCGDNIH2_RS02635 d906b3ed47bd525953a67793aee6dc74 485 Hamap MF_01603 Bifunctional protein HldE [hldE]. 1 484 40.386 T 29-03-2018 IPR023030 Bifunctional protein HldE GO:0016773|GO:0016779 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.7.70+2.7.1.167 GBCGDNIH2_RS02635 d906b3ed47bd525953a67793aee6dc74 485 Pfam PF00294 pfkB family carbohydrate kinase 6 309 4.3E-33 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB GBCGDNIH2_RS11175 63c8c8ca1d8912344d73a49e3861084a 320 Pfam PF03631 Virulence factor BrkB 59 311 1.7E-55 T 29-03-2018 IPR017039 Virulence factor BrkB GBCGDNIH2_RS11175 63c8c8ca1d8912344d73a49e3861084a 320 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 58 310 4.1E-23 T 29-03-2018 IPR017039 Virulence factor BrkB GBCGDNIH2_RS11175 63c8c8ca1d8912344d73a49e3861084a 320 PIRSF PIRSF035875 33 320 2.0E-55 T 29-03-2018 IPR017039 Virulence factor BrkB GBCGDNIH2_RS07740 1002a5d191784c040d9adf092dac483f 246 Pfam PF00005 ABC transporter 15 163 1.8E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GBCGDNIH2_RS07740 1002a5d191784c040d9adf092dac483f 246 SMART SM00382 23 222 6.0E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS07740 1002a5d191784c040d9adf092dac483f 246 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GBCGDNIH2_RS07740 1002a5d191784c040d9adf092dac483f 246 SUPERFAMILY SSF52540 2 236 1.5E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS07740 1002a5d191784c040d9adf092dac483f 246 Gene3D G3DSA:3.40.50.300 1 245 8.5E-53 T 29-03-2018 GBCGDNIH2_RS04160 f8af586ce698d6e6e00d686feae94779 316 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 7 303 8.4E-94 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 GBCGDNIH2_RS04160 f8af586ce698d6e6e00d686feae94779 316 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 7 148 8.9E-41 T 29-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 GBCGDNIH2_RS04160 f8af586ce698d6e6e00d686feae94779 316 Gene3D G3DSA:3.40.50.1370 163 306 1.4E-49 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 GBCGDNIH2_RS04160 f8af586ce698d6e6e00d686feae94779 316 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 5 306 40.341 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 GBCGDNIH2_RS04160 f8af586ce698d6e6e00d686feae94779 316 SUPERFAMILY SSF53671 3 305 3.27E-99 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 GBCGDNIH2_RS04160 f8af586ce698d6e6e00d686feae94779 316 Gene3D G3DSA:3.40.50.1370 1 162 4.6E-64 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 GBCGDNIH2_RS04160 f8af586ce698d6e6e00d686feae94779 316 PRINTS PR00101 Aspartate carbamoyltransferase signature 285 299 4.5E-32 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 GBCGDNIH2_RS04160 f8af586ce698d6e6e00d686feae94779 316 PRINTS PR00101 Aspartate carbamoyltransferase signature 80 89 4.5E-32 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 GBCGDNIH2_RS04160 f8af586ce698d6e6e00d686feae94779 316 PRINTS PR00101 Aspartate carbamoyltransferase signature 219 228 4.5E-32 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 GBCGDNIH2_RS04160 f8af586ce698d6e6e00d686feae94779 316 PRINTS PR00101 Aspartate carbamoyltransferase signature 42 64 4.5E-32 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 GBCGDNIH2_RS04160 f8af586ce698d6e6e00d686feae94779 316 PRINTS PR00101 Aspartate carbamoyltransferase signature 135 152 4.5E-32 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 GBCGDNIH2_RS04160 f8af586ce698d6e6e00d686feae94779 316 PRINTS PR00101 Aspartate carbamoyltransferase signature 260 265 4.5E-32 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 GBCGDNIH2_RS04160 f8af586ce698d6e6e00d686feae94779 316 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 52 71 3.0E-16 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 GBCGDNIH2_RS04160 f8af586ce698d6e6e00d686feae94779 316 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 256 265 3.0E-16 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 GBCGDNIH2_RS04160 f8af586ce698d6e6e00d686feae94779 316 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 136 147 3.0E-16 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 GBCGDNIH2_RS04160 f8af586ce698d6e6e00d686feae94779 316 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 268 291 3.0E-16 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 GBCGDNIH2_RS04160 f8af586ce698d6e6e00d686feae94779 316 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 155 302 1.7E-23 T 29-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 GBCGDNIH2_RS04160 f8af586ce698d6e6e00d686feae94779 316 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 52 59 - T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 GBCGDNIH2_RS03355 4ba28030957cfa450e9d78e8e69c94c8 392 SUPERFAMILY SSF55124 214 277 4.42E-6 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 GBCGDNIH2_RS03355 4ba28030957cfa450e9d78e8e69c94c8 392 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 11 77 3.4E-12 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 GBCGDNIH2_RS03355 4ba28030957cfa450e9d78e8e69c94c8 392 Gene3D G3DSA:3.90.480.10 20 294 1.9E-27 T 29-03-2018 GBCGDNIH2_RS03355 4ba28030957cfa450e9d78e8e69c94c8 392 SUPERFAMILY SSF56014 296 386 3.66E-12 T 29-03-2018 GBCGDNIH2_RS03355 4ba28030957cfa450e9d78e8e69c94c8 392 SUPERFAMILY SSF55124 2 81 3.05E-19 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 GBCGDNIH2_RS03355 4ba28030957cfa450e9d78e8e69c94c8 392 Gene3D G3DSA:3.30.413.10 295 384 7.1E-9 T 29-03-2018 GBCGDNIH2_RS03600 ba654d75b296354705277a3ffba955e2 1524 SUPERFAMILY SSF69336 1249 1511 5.62E-91 T 29-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 GBCGDNIH2_RS03600 ba654d75b296354705277a3ffba955e2 1524 Pfam PF01645 Conserved region in glutamate synthase 836 1199 8.1E-152 T 29-03-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 GBCGDNIH2_RS03600 ba654d75b296354705277a3ffba955e2 1524 Gene3D G3DSA:3.60.20.10 47 472 7.6E-136 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal GBCGDNIH2_RS03600 ba654d75b296354705277a3ffba955e2 1524 Gene3D G3DSA:3.20.20.70 473 816 3.2E-80 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS03600 ba654d75b296354705277a3ffba955e2 1524 Pfam PF04898 Glutamate synthase central domain 492 773 8.5E-100 T 29-03-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 GBCGDNIH2_RS03600 ba654d75b296354705277a3ffba955e2 1524 SUPERFAMILY SSF51395 480 1235 9.16E-260 T 29-03-2018 GBCGDNIH2_RS03600 ba654d75b296354705277a3ffba955e2 1524 SUPERFAMILY SSF56235 47 465 3.43E-141 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal GBCGDNIH2_RS03600 ba654d75b296354705277a3ffba955e2 1524 Gene3D G3DSA:2.160.20.60 1252 1522 1.1E-96 T 29-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 GBCGDNIH2_RS03600 ba654d75b296354705277a3ffba955e2 1524 Gene3D G3DSA:3.20.20.70 817 1249 9.3E-148 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS03600 ba654d75b296354705277a3ffba955e2 1524 Pfam PF01493 GXGXG motif 1278 1456 1.0E-73 T 29-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 GBCGDNIH2_RS03600 ba654d75b296354705277a3ffba955e2 1524 Pfam PF00310 Glutamine amidotransferases class-II 47 463 6.7E-150 T 29-03-2018 IPR017932 Glutamine amidotransferase type 2 domain GBCGDNIH2_RS00160 eef01f998ea270e2d6728e25302edbbd 799 Pfam PF03176 MMPL family 212 426 2.2E-8 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 GBCGDNIH2_RS00160 eef01f998ea270e2d6728e25302edbbd 799 Gene3D G3DSA:1.20.1640.10 201 395 1.3E-14 T 29-03-2018 GBCGDNIH2_RS00160 eef01f998ea270e2d6728e25302edbbd 799 Gene3D G3DSA:1.20.1640.10 603 784 4.2E-16 T 29-03-2018 GBCGDNIH2_RS00160 eef01f998ea270e2d6728e25302edbbd 799 SUPERFAMILY SSF82866 218 392 1.31E-14 T 29-03-2018 GBCGDNIH2_RS00160 eef01f998ea270e2d6728e25302edbbd 799 SUPERFAMILY SSF82866 627 782 1.15E-14 T 29-03-2018 GBCGDNIH2_RS02185 e11bfcd35d4b38e0f053cc40e1571049 432 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 31 397 1.3E-104 T 29-03-2018 IPR020823 Cell division protein FtsA GO:0007049 GBCGDNIH2_RS02185 e11bfcd35d4b38e0f053cc40e1571049 432 Pfam PF14450 Cell division protein FtsA 31 211 3.2E-9 T 29-03-2018 GBCGDNIH2_RS02185 e11bfcd35d4b38e0f053cc40e1571049 432 Pfam PF14450 Cell division protein FtsA 227 395 6.0E-21 T 29-03-2018 GBCGDNIH2_RS02185 e11bfcd35d4b38e0f053cc40e1571049 432 SUPERFAMILY SSF53067 218 397 9.72E-42 T 29-03-2018 GBCGDNIH2_RS02185 e11bfcd35d4b38e0f053cc40e1571049 432 SMART SM00842 29 215 1.9E-82 T 29-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 GBCGDNIH2_RS02185 e11bfcd35d4b38e0f053cc40e1571049 432 Gene3D G3DSA:3.30.420.40 227 372 7.6E-23 T 29-03-2018 GBCGDNIH2_RS02185 e11bfcd35d4b38e0f053cc40e1571049 432 PIRSF PIRSF003101 20 432 5.4E-143 T 29-03-2018 IPR020823 Cell division protein FtsA GO:0007049 GBCGDNIH2_RS02185 e11bfcd35d4b38e0f053cc40e1571049 432 Hamap MF_02033 Cell division protein FtsA [ftsA]. 25 432 25.721 T 29-03-2018 IPR020823 Cell division protein FtsA GO:0007049 GBCGDNIH2_RS02185 e11bfcd35d4b38e0f053cc40e1571049 432 Pfam PF02491 SHS2 domain inserted in FTSA 108 180 1.9E-18 T 29-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 GBCGDNIH2_RS02185 e11bfcd35d4b38e0f053cc40e1571049 432 Gene3D G3DSA:3.30.420.40 29 158 7.4E-28 T 29-03-2018 GBCGDNIH2_RS02185 e11bfcd35d4b38e0f053cc40e1571049 432 SUPERFAMILY SSF53067 31 216 5.18E-44 T 29-03-2018 GBCGDNIH2_RS01785 318f84209f8d2e6ed16d392f760c841e 625 Pfam PF01011 PQQ enzyme repeat 514 550 1.2E-6 T 29-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat GBCGDNIH2_RS01785 318f84209f8d2e6ed16d392f760c841e 625 TIGRFAM TIGR03075 PQQ_enz_alc_DH: PQQ-dependent dehydrogenase, methanol/ethanol family 25 568 1.4E-201 T 29-03-2018 IPR017512 PQQ-dependent dehydrogenase, methanol/ethanol family GO:0005509|GO:0016020|GO:0016614|GO:0055114 GBCGDNIH2_RS01785 318f84209f8d2e6ed16d392f760c841e 625 Pfam PF13360 PQQ-like domain 84 227 5.9E-8 T 29-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat GBCGDNIH2_RS01785 318f84209f8d2e6ed16d392f760c841e 625 SUPERFAMILY SSF50998 37 622 5.89E-166 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily GBCGDNIH2_RS01785 318f84209f8d2e6ed16d392f760c841e 625 ProSitePatterns PS00364 Bacterial quinoprotein dehydrogenases signature 2. 272 293 - T 29-03-2018 IPR001479 Quinoprotein dehydrogenase, conserved site GO:0030288|GO:0055114 GBCGDNIH2_RS01785 318f84209f8d2e6ed16d392f760c841e 625 SMART SM00564 191 228 0.0072 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat GBCGDNIH2_RS01785 318f84209f8d2e6ed16d392f760c841e 625 SMART SM00564 150 177 67.0 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat GBCGDNIH2_RS01785 318f84209f8d2e6ed16d392f760c841e 625 SMART SM00564 509 540 3.3E-4 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat GBCGDNIH2_RS01785 318f84209f8d2e6ed16d392f760c841e 625 Gene3D G3DSA:2.140.10.10 30 624 5.5E-108 T 29-03-2018 GBCGDNIH2_RS10865 11aeea1258151ae2226cdd64f467bc14 162 Pfam PF02391 MoaE protein 10 125 1.3E-29 T 29-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 GBCGDNIH2_RS10865 11aeea1258151ae2226cdd64f467bc14 162 SUPERFAMILY SSF54690 7 156 1.16E-42 T 29-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 GBCGDNIH2_RS10865 11aeea1258151ae2226cdd64f467bc14 162 Gene3D G3DSA:3.90.1170.40 4 157 2.4E-49 T 29-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 GBCGDNIH2_RS04250 f4acea0bb561a64ae5c35306e93960ae 544 Pfam PF00117 Glutamine amidotransferase class-I 302 535 8.6E-57 T 29-03-2018 IPR017926 Glutamine amidotransferase GBCGDNIH2_RS04250 f4acea0bb561a64ae5c35306e93960ae 544 SUPERFAMILY SSF52540 1 267 9.45E-119 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS04250 f4acea0bb561a64ae5c35306e93960ae 544 Pfam PF06418 CTP synthase N-terminus 3 266 1.7E-120 T 29-03-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 GBCGDNIH2_RS04250 f4acea0bb561a64ae5c35306e93960ae 544 Hamap MF_01227 CTP synthase [pyrG]. 2 541 50.194 T 29-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 GBCGDNIH2_RS04250 f4acea0bb561a64ae5c35306e93960ae 544 Gene3D G3DSA:3.40.50.880 287 543 2.2E-67 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like GBCGDNIH2_RS04250 f4acea0bb561a64ae5c35306e93960ae 544 TIGRFAM TIGR00337 PyrG: CTP synthase 2 536 1.0E-228 T 29-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 GBCGDNIH2_RS04250 f4acea0bb561a64ae5c35306e93960ae 544 SUPERFAMILY SSF52317 291 539 1.72E-77 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like GBCGDNIH2_RS04250 f4acea0bb561a64ae5c35306e93960ae 544 Gene3D G3DSA:3.40.50.300 1 286 2.4E-123 T 29-03-2018 GBCGDNIH2_RS09870 82354cc68bd7489d27d90936434c6674 204 Gene3D G3DSA:2.40.40.10 93 202 3.5E-14 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain GBCGDNIH2_RS09870 82354cc68bd7489d27d90936434c6674 204 Pfam PF03330 Lytic transglycolase 113 200 3.7E-17 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain GBCGDNIH2_RS09870 82354cc68bd7489d27d90936434c6674 204 Hamap MF_02071 Endolytic peptidoglycan transglycosylase RlpA [rlpA]. 21 204 19.77 T 29-03-2018 IPR034718 Endolytic peptidoglycan transglycosylase RlpA GO:0016829 GBCGDNIH2_RS09870 82354cc68bd7489d27d90936434c6674 204 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 115 202 1.5E-27 T 29-03-2018 IPR012997 Rare lipoprotein A GBCGDNIH2_RS09870 82354cc68bd7489d27d90936434c6674 204 SUPERFAMILY SSF50685 107 200 3.92E-11 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain GBCGDNIH2_RS03965 67000aa75a63b9a8d65e894b93b1c4a3 169 SUPERFAMILY SSF54211 6 167 2.05E-66 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold GBCGDNIH2_RS03965 67000aa75a63b9a8d65e894b93b1c4a3 169 TIGRFAM TIGR03126 one_C_fae: formaldehyde-activating enzyme 8 166 2.2E-72 T 29-03-2018 IPR014826 Formaldehyde-activating enzyme GO:0016051|GO:0016840 KEGG: 00030+4.1.2.43|KEGG: 00680+4.2.1.147+4.1.2.43|MetaCyc: PWY-1723|MetaCyc: PWY-1861|MetaCyc: PWY-7796 GBCGDNIH2_RS03965 67000aa75a63b9a8d65e894b93b1c4a3 169 Pfam PF08714 Formaldehyde-activating enzyme (Fae) 9 166 3.9E-69 T 29-03-2018 IPR014826 Formaldehyde-activating enzyme GO:0016051|GO:0016840 KEGG: 00030+4.1.2.43|KEGG: 00680+4.2.1.147+4.1.2.43|MetaCyc: PWY-1723|MetaCyc: PWY-1861|MetaCyc: PWY-7796 GBCGDNIH2_RS03965 67000aa75a63b9a8d65e894b93b1c4a3 169 Gene3D G3DSA:3.30.230.60 7 167 3.3E-75 T 29-03-2018 IPR014826 Formaldehyde-activating enzyme GO:0016051|GO:0016840 KEGG: 00030+4.1.2.43|KEGG: 00680+4.2.1.147+4.1.2.43|MetaCyc: PWY-1723|MetaCyc: PWY-1861|MetaCyc: PWY-7796 GBCGDNIH2_RS04970 99700bea3dd3b12079d5bab187e6c731 245 SUPERFAMILY SSF109755 12 232 1.36E-72 T 29-03-2018 GBCGDNIH2_RS04970 99700bea3dd3b12079d5bab187e6c731 245 PIRSF PIRSF003107 8 226 3.8E-65 T 29-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 GBCGDNIH2_RS04970 99700bea3dd3b12079d5bab187e6c731 245 Gene3D G3DSA:1.20.58.220 6 118 2.1E-28 T 29-03-2018 GBCGDNIH2_RS04970 99700bea3dd3b12079d5bab187e6c731 245 Pfam PF01895 PhoU domain 25 112 7.5E-23 T 29-03-2018 IPR026022 PhoU domain GBCGDNIH2_RS04970 99700bea3dd3b12079d5bab187e6c731 245 Pfam PF01895 PhoU domain 128 212 4.2E-20 T 29-03-2018 IPR026022 PhoU domain GBCGDNIH2_RS04970 99700bea3dd3b12079d5bab187e6c731 245 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 13 219 2.1E-68 T 29-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 GBCGDNIH2_RS04970 99700bea3dd3b12079d5bab187e6c731 245 Gene3D G3DSA:1.20.58.220 125 238 6.8E-29 T 29-03-2018 GBCGDNIH2_RS10580 71034ffd9cdf2d1eee9b12f72cc2ee44 676 SUPERFAMILY SSF49503 524 675 3.77E-38 T 29-03-2018 IPR008972 Cupredoxin GBCGDNIH2_RS10580 71034ffd9cdf2d1eee9b12f72cc2ee44 676 SUPERFAMILY SSF49503 61 192 4.08E-38 T 29-03-2018 IPR008972 Cupredoxin GBCGDNIH2_RS10580 71034ffd9cdf2d1eee9b12f72cc2ee44 676 Pfam PF00394 Multicopper oxidase 179 353 3.0E-27 T 29-03-2018 IPR001117 Multicopper oxidase, type 1 GO:0055114 GBCGDNIH2_RS10580 71034ffd9cdf2d1eee9b12f72cc2ee44 676 Pfam PF07731 Multicopper oxidase 559 675 4.1E-25 T 29-03-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 GBCGDNIH2_RS10580 71034ffd9cdf2d1eee9b12f72cc2ee44 676 ProSitePatterns PS00080 Multicopper oxidases signature 2. 658 669 - T 29-03-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 GBCGDNIH2_RS10580 71034ffd9cdf2d1eee9b12f72cc2ee44 676 Gene3D G3DSA:2.60.40.420 422 676 6.2E-50 T 29-03-2018 IPR008972 Cupredoxin GBCGDNIH2_RS10580 71034ffd9cdf2d1eee9b12f72cc2ee44 676 SUPERFAMILY SSF49503 174 386 2.94E-54 T 29-03-2018 IPR008972 Cupredoxin GBCGDNIH2_RS10580 71034ffd9cdf2d1eee9b12f72cc2ee44 676 TIGRFAM TIGR01480 copper_res_A: copper-resistance protein, CopA family 13 433 1.3E-157 T 29-03-2018 IPR006376 Copper-resistance protein CopA GO:0005507|GO:0042597 GBCGDNIH2_RS10580 71034ffd9cdf2d1eee9b12f72cc2ee44 676 Pfam PF07732 Multicopper oxidase 66 169 8.0E-38 T 29-03-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 GBCGDNIH2_RS10580 71034ffd9cdf2d1eee9b12f72cc2ee44 676 Gene3D G3DSA:2.60.40.420 174 390 3.2E-35 T 29-03-2018 IPR008972 Cupredoxin GBCGDNIH2_RS10580 71034ffd9cdf2d1eee9b12f72cc2ee44 676 Gene3D G3DSA:2.60.40.420 33 168 2.7E-31 T 29-03-2018 IPR008972 Cupredoxin GBCGDNIH2_RS05205 1a81acecad7536b6aa4d2f0cdb4d24ae 112 SUPERFAMILY SSF54913 1 112 2.56E-47 T 29-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta GBCGDNIH2_RS05205 1a81acecad7536b6aa4d2f0cdb4d24ae 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 29-03-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 GBCGDNIH2_RS05205 1a81acecad7536b6aa4d2f0cdb4d24ae 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 29-03-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 GBCGDNIH2_RS05205 1a81acecad7536b6aa4d2f0cdb4d24ae 112 PRINTS PR00340 P-II protein signature 52 75 5.2E-45 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 GBCGDNIH2_RS05205 1a81acecad7536b6aa4d2f0cdb4d24ae 112 PRINTS PR00340 P-II protein signature 23 41 5.2E-45 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 GBCGDNIH2_RS05205 1a81acecad7536b6aa4d2f0cdb4d24ae 112 PRINTS PR00340 P-II protein signature 83 103 5.2E-45 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 GBCGDNIH2_RS05205 1a81acecad7536b6aa4d2f0cdb4d24ae 112 PRINTS PR00340 P-II protein signature 2 17 5.2E-45 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 GBCGDNIH2_RS05205 1a81acecad7536b6aa4d2f0cdb4d24ae 112 PIRSF PIRSF039144 1 112 6.1E-55 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 GBCGDNIH2_RS05205 1a81acecad7536b6aa4d2f0cdb4d24ae 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 2.9E-44 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 GBCGDNIH2_RS05205 1a81acecad7536b6aa4d2f0cdb4d24ae 112 Gene3D G3DSA:3.30.70.120 1 109 6.9E-53 T 29-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal GBCGDNIH2_RS05205 1a81acecad7536b6aa4d2f0cdb4d24ae 112 SMART SM00938 4 105 5.6E-69 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 GBCGDNIH2_RS10820 ef91211ad23e6cedc1ff295fb470707c 603 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 17 603 1.8E-298 T 29-03-2018 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 GBCGDNIH2_RS10820 ef91211ad23e6cedc1ff295fb470707c 603 Gene3D G3DSA:3.50.50.60 2 315 5.1E-49 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS10820 ef91211ad23e6cedc1ff295fb470707c 603 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 20 603 5.1E-240 T 29-03-2018 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 GBCGDNIH2_RS10820 ef91211ad23e6cedc1ff295fb470707c 603 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 54 63 - T 29-03-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 GBCGDNIH2_RS10820 ef91211ad23e6cedc1ff295fb470707c 603 Gene3D G3DSA:4.10.80.40 552 603 1.1E-22 T 29-03-2018 GBCGDNIH2_RS10820 ef91211ad23e6cedc1ff295fb470707c 603 SUPERFAMILY SSF46977 462 603 2.09E-47 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 GBCGDNIH2_RS10820 ef91211ad23e6cedc1ff295fb470707c 603 Pfam PF02910 Fumarate reductase flavoprotein C-term 470 603 7.9E-43 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 GBCGDNIH2_RS10820 ef91211ad23e6cedc1ff295fb470707c 603 SUPERFAMILY SSF51905 369 438 5.19E-80 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS10820 ef91211ad23e6cedc1ff295fb470707c 603 SUPERFAMILY SSF51905 12 270 5.19E-80 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS10820 ef91211ad23e6cedc1ff295fb470707c 603 Gene3D G3DSA:1.20.58.100 441 551 1.8E-33 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 GBCGDNIH2_RS10820 ef91211ad23e6cedc1ff295fb470707c 603 Pfam PF00890 FAD binding domain 20 415 1.2E-120 T 29-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 GBCGDNIH2_RS10820 ef91211ad23e6cedc1ff295fb470707c 603 Gene3D G3DSA:3.50.50.60 324 431 5.0E-18 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS10820 ef91211ad23e6cedc1ff295fb470707c 603 SUPERFAMILY SSF56425 247 365 2.24E-41 T 29-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 GBCGDNIH2_RS10820 ef91211ad23e6cedc1ff295fb470707c 603 PIRSF PIRSF000171 10 592 2.1E-34 T 29-03-2018 GBCGDNIH2_RS12405 e37dc2e09cfc1d07b332b6d53215576d 915 Gene3D G3DSA:3.40.50.300 409 581 1.8E-38 T 29-03-2018 GBCGDNIH2_RS12405 e37dc2e09cfc1d07b332b6d53215576d 915 Pfam PF00009 Elongation factor Tu GTP binding domain 419 576 2.1E-31 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GBCGDNIH2_RS12405 e37dc2e09cfc1d07b332b6d53215576d 915 SUPERFAMILY SSF50447 587 670 3.95E-26 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain GBCGDNIH2_RS12405 e37dc2e09cfc1d07b332b6d53215576d 915 ProSitePatterns PS01176 Initiation factor 2 signature. 868 890 - T 29-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 GBCGDNIH2_RS12405 e37dc2e09cfc1d07b332b6d53215576d 915 SUPERFAMILY SSF52540 409 587 1.17E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS12405 e37dc2e09cfc1d07b332b6d53215576d 915 Gene3D G3DSA:2.40.30.10 818 914 6.0E-30 T 29-03-2018 GBCGDNIH2_RS12405 e37dc2e09cfc1d07b332b6d53215576d 915 Pfam PF11987 Translation-initiation factor 2 702 807 5.4E-34 T 29-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 GBCGDNIH2_RS12405 e37dc2e09cfc1d07b332b6d53215576d 915 Pfam PF08364 Bacterial translation initiation factor IF-2 associated region 20 55 1.4E-12 T 29-03-2018 IPR013575 Initiation factor 2 associated domain, bacterial GBCGDNIH2_RS12405 e37dc2e09cfc1d07b332b6d53215576d 915 Gene3D G3DSA:3.30.56.50 341 382 5.1E-9 T 29-03-2018 GBCGDNIH2_RS12405 e37dc2e09cfc1d07b332b6d53215576d 915 SUPERFAMILY SSF52156 701 824 3.79E-32 T 29-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 GBCGDNIH2_RS12405 e37dc2e09cfc1d07b332b6d53215576d 915 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 417 571 7.2E-32 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 GBCGDNIH2_RS12405 e37dc2e09cfc1d07b332b6d53215576d 915 SUPERFAMILY SSF50447 819 912 5.5E-33 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain GBCGDNIH2_RS12405 e37dc2e09cfc1d07b332b6d53215576d 915 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 333 911 2.6E-244 T 29-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 GBCGDNIH2_RS12405 e37dc2e09cfc1d07b332b6d53215576d 915 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 338 388 4.1E-16 T 29-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal GBCGDNIH2_RS12405 e37dc2e09cfc1d07b332b6d53215576d 915 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 11 915 17.037 T 29-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 GBCGDNIH2_RS12405 e37dc2e09cfc1d07b332b6d53215576d 915 Gene3D G3DSA:2.40.30.10 582 680 1.3E-15 T 29-03-2018 GBCGDNIH2_RS12405 e37dc2e09cfc1d07b332b6d53215576d 915 Gene3D G3DSA:3.40.50.10050 715 796 2.3E-27 T 29-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 GBCGDNIH2_RS12545 ad9054e69476b582bd5301556fcabb24 434 Gene3D G3DSA:1.25.40.10 220 293 0.023 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS12545 ad9054e69476b582bd5301556fcabb24 434 SUPERFAMILY SSF48452 165 341 1.13E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS12545 ad9054e69476b582bd5301556fcabb24 434 Gene3D G3DSA:1.25.40.10 294 383 5.7E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS12545 ad9054e69476b582bd5301556fcabb24 434 Pfam PF07219 HemY protein N-terminus 35 133 5.9E-21 T 29-03-2018 IPR010817 HemY, N-terminal GBCGDNIH2_RS12545 ad9054e69476b582bd5301556fcabb24 434 Gene3D G3DSA:1.25.40.10 69 217 2.9E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS07760 14d02323c93071dbb6ea23db46d09d1b 205 Pfam PF14246 AefR-like transcriptional repressor, C-terminal region 147 201 1.2E-16 T 29-03-2018 GBCGDNIH2_RS07760 14d02323c93071dbb6ea23db46d09d1b 205 SUPERFAMILY SSF48498 80 201 1.93E-10 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal GBCGDNIH2_RS07760 14d02323c93071dbb6ea23db46d09d1b 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 58 1.1E-17 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GBCGDNIH2_RS07760 14d02323c93071dbb6ea23db46d09d1b 205 Gene3D G3DSA:1.10.10.60 7 59 8.9E-19 T 29-03-2018 GBCGDNIH2_RS07760 14d02323c93071dbb6ea23db46d09d1b 205 Gene3D G3DSA:1.10.357.10 60 205 1.6E-24 T 29-03-2018 GBCGDNIH2_RS07760 14d02323c93071dbb6ea23db46d09d1b 205 ProSitePatterns PS01081 TetR-type HTH domain signature. 27 57 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site GBCGDNIH2_RS07760 14d02323c93071dbb6ea23db46d09d1b 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 3.9E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GBCGDNIH2_RS07760 14d02323c93071dbb6ea23db46d09d1b 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 3.9E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GBCGDNIH2_RS07760 14d02323c93071dbb6ea23db46d09d1b 205 SUPERFAMILY SSF46689 4 86 2.43E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 GBCGDNIH2_RS02805 9c79a8bd92735175c8bcbd115f439831 1391 ProSitePatterns PS01166 RNA polymerases beta chain signature. 1109 1121 - T 29-03-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GBCGDNIH2_RS02805 9c79a8bd92735175c8bcbd115f439831 1391 Gene3D G3DSA:2.40.270.10 1091 1289 3.6E-80 T 29-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GBCGDNIH2_RS02805 9c79a8bd92735175c8bcbd115f439831 1391 Pfam PF04561 RNA polymerase Rpb2, domain 2 390 489 9.2E-17 T 29-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GBCGDNIH2_RS02805 9c79a8bd92735175c8bcbd115f439831 1391 Pfam PF04565 RNA polymerase Rpb2, domain 3 548 616 6.7E-32 T 29-03-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GBCGDNIH2_RS02805 9c79a8bd92735175c8bcbd115f439831 1391 Gene3D G3DSA:2.40.50.100 749 828 1.2E-25 T 29-03-2018 GBCGDNIH2_RS02805 9c79a8bd92735175c8bcbd115f439831 1391 Pfam PF04560 RNA polymerase Rpb2, domain 7 1313 1387 1.1E-26 T 29-03-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GBCGDNIH2_RS02805 9c79a8bd92735175c8bcbd115f439831 1391 Gene3D G3DSA:3.90.1100.10 468 680 1.6E-78 T 29-03-2018 GBCGDNIH2_RS02805 9c79a8bd92735175c8bcbd115f439831 1391 Gene3D G3DSA:3.90.1100.10 681 748 7.9E-14 T 29-03-2018 GBCGDNIH2_RS02805 9c79a8bd92735175c8bcbd115f439831 1391 Pfam PF04563 RNA polymerase beta subunit 34 532 1.8E-28 T 29-03-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GBCGDNIH2_RS02805 9c79a8bd92735175c8bcbd115f439831 1391 Gene3D G3DSA:3.90.1800.10 1314 1356 9.8E-12 T 29-03-2018 GBCGDNIH2_RS02805 9c79a8bd92735175c8bcbd115f439831 1391 Pfam PF00562 RNA polymerase Rpb2, domain 6 752 1311 2.2E-165 T 29-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GBCGDNIH2_RS02805 9c79a8bd92735175c8bcbd115f439831 1391 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 20 1389 12.324 T 29-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GBCGDNIH2_RS02805 9c79a8bd92735175c8bcbd115f439831 1391 Pfam PF10385 RNA polymerase beta subunit external 1 domain 626 691 6.4E-21 T 29-03-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GBCGDNIH2_RS02805 9c79a8bd92735175c8bcbd115f439831 1391 SUPERFAMILY SSF64484 378 972 0.0 T 29-03-2018 GBCGDNIH2_RS02805 9c79a8bd92735175c8bcbd115f439831 1391 SUPERFAMILY SSF64484 19 240 0.0 T 29-03-2018 GBCGDNIH2_RS02805 9c79a8bd92735175c8bcbd115f439831 1391 SUPERFAMILY SSF64484 1085 1388 0.0 T 29-03-2018 GBCGDNIH2_RS02805 9c79a8bd92735175c8bcbd115f439831 1391 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 16 1385 0.0 T 29-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GBCGDNIH2_RS02805 9c79a8bd92735175c8bcbd115f439831 1391 Gene3D G3DSA:2.40.50.150 862 1090 5.5E-55 T 29-03-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GBCGDNIH2_RS02805 9c79a8bd92735175c8bcbd115f439831 1391 Gene3D G3DSA:3.90.1110.10 161 467 5.4E-67 T 29-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GBCGDNIH2_RS12245 6138165cf1fab182021e617146f9b98a 220 Gene3D G3DSA:3.40.109.10 34 220 6.0E-36 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 GBCGDNIH2_RS12245 6138165cf1fab182021e617146f9b98a 220 Hamap MF_01204 Probable malonic semialdehyde reductase RutE [rutE]. 26 220 41.652 T 29-03-2018 IPR023936 NADH dehydrogenase/NAD(P)H nitroreductase, putative, RutE GO:0016491|GO:0055114 GBCGDNIH2_RS12245 6138165cf1fab182021e617146f9b98a 220 Pfam PF00881 Nitroreductase family 48 198 1.7E-14 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 GBCGDNIH2_RS12245 6138165cf1fab182021e617146f9b98a 220 SUPERFAMILY SSF55469 37 218 6.81E-42 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 GBCGDNIH2_RS05365 bc408849ffb31080b4bf6d895b4eb773 145 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 1 131 1.2E-25 T 29-03-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 GBCGDNIH2_RS05365 bc408849ffb31080b4bf6d895b4eb773 145 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 8 101 4.0E-31 T 29-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 GBCGDNIH2_RS05365 bc408849ffb31080b4bf6d895b4eb773 145 Gene3D G3DSA:3.90.470.20 1 136 2.2E-30 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 GBCGDNIH2_RS05365 bc408849ffb31080b4bf6d895b4eb773 145 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 4 99 1.2E-16 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 GBCGDNIH2_RS05365 bc408849ffb31080b4bf6d895b4eb773 145 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 3 131 23.129 T 29-03-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 GBCGDNIH2_RS05365 bc408849ffb31080b4bf6d895b4eb773 145 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 2 130 1.1E-21 T 29-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 GBCGDNIH2_RS05365 bc408849ffb31080b4bf6d895b4eb773 145 SUPERFAMILY SSF56214 1 129 5.1E-27 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 GBCGDNIH2_RS11490 04bdc36d5a7b66464bda30165f7e3079 507 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 21 499 5.6E-147 T 29-03-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 GBCGDNIH2_RS11490 04bdc36d5a7b66464bda30165f7e3079 507 SUPERFAMILY SSF52540 465 489 5.73E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS11490 04bdc36d5a7b66464bda30165f7e3079 507 SUPERFAMILY SSF52540 202 431 5.73E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS11490 04bdc36d5a7b66464bda30165f7e3079 507 Pfam PF00772 DnaB-like helicase N terminal domain 22 123 4.4E-24 T 29-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 GBCGDNIH2_RS11490 04bdc36d5a7b66464bda30165f7e3079 507 Gene3D G3DSA:3.40.50.300 186 506 3.8E-64 T 29-03-2018 GBCGDNIH2_RS11490 04bdc36d5a7b66464bda30165f7e3079 507 Pfam PF03796 DnaB-like helicase C terminal domain 204 497 1.4E-99 T 29-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 GBCGDNIH2_RS11490 04bdc36d5a7b66464bda30165f7e3079 507 SMART SM00382 221 433 7.8E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS11490 04bdc36d5a7b66464bda30165f7e3079 507 Gene3D G3DSA:1.10.860.10 16 169 1.1E-35 T 29-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal GBCGDNIH2_RS11490 04bdc36d5a7b66464bda30165f7e3079 507 SUPERFAMILY SSF48024 20 131 2.62E-28 T 29-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 GBCGDNIH2_RS01440 2108bdcf8db4ef9b47db585e2ef6f744 292 SUPERFAMILY SSF53187 206 282 4.39E-50 T 29-03-2018 GBCGDNIH2_RS01440 2108bdcf8db4ef9b47db585e2ef6f744 292 SUPERFAMILY SSF53187 63 159 4.39E-50 T 29-03-2018 GBCGDNIH2_RS01440 2108bdcf8db4ef9b47db585e2ef6f744 292 SMART SM00646 125 279 4.2E-28 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 GBCGDNIH2_RS01440 2108bdcf8db4ef9b47db585e2ef6f744 292 Gene3D G3DSA:3.40.630.40 64 284 6.7E-51 T 29-03-2018 GBCGDNIH2_RS01440 2108bdcf8db4ef9b47db585e2ef6f744 292 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 65 279 1.0E-45 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 GBCGDNIH2_RS02570 909ea3e29547c04f5814d37fa4440317 30 Pfam PF08042 PqqA family 6 24 7.5E-8 T 29-03-2018 IPR011725 Coenzyme PQQ biosynthesis protein A GO:0018189 GBCGDNIH2_RS02570 909ea3e29547c04f5814d37fa4440317 30 Hamap MF_00656 Coenzyme PQQ synthesis protein A [pqqA]. 6 28 10.483 T 29-03-2018 IPR011725 Coenzyme PQQ biosynthesis protein A GO:0018189 GBCGDNIH2_RS02570 909ea3e29547c04f5814d37fa4440317 30 TIGRFAM TIGR02107 PQQ_syn_pqqA: coenzyme PQQ precursor peptide PqqA 7 27 3.8E-10 T 29-03-2018 IPR011725 Coenzyme PQQ biosynthesis protein A GO:0018189 GBCGDNIH2_RS10350 d53557ae13673500355fe8d62babecc0 282 Gene3D G3DSA:1.10.600.10 2 280 8.3E-79 T 29-03-2018 IPR008949 Isoprenoid synthase domain GBCGDNIH2_RS10350 d53557ae13673500355fe8d62babecc0 282 TIGRFAM TIGR03465 HpnD: squalene synthase HpnD 18 281 1.5E-101 T 29-03-2018 IPR017828 Squalene/phytoene synthase HpnD GO:0016117|GO:0016767 GBCGDNIH2_RS10350 d53557ae13673500355fe8d62babecc0 282 SUPERFAMILY SSF48576 10 279 7.19E-75 T 29-03-2018 IPR008949 Isoprenoid synthase domain GBCGDNIH2_RS10350 d53557ae13673500355fe8d62babecc0 282 ProSitePatterns PS01045 Squalene and phytoene synthases signature 2. 160 185 - T 29-03-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 GBCGDNIH2_RS10350 d53557ae13673500355fe8d62babecc0 282 Pfam PF00494 Squalene/phytoene synthase 19 271 2.9E-72 T 29-03-2018 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 GBCGDNIH2_RS10555 69e1e4f879d15749aac9a4616bae185f 454 Gene3D G3DSA:3.65.10.10 238 454 2.8E-46 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 GBCGDNIH2_RS10555 69e1e4f879d15749aac9a4616bae185f 454 ProSitePatterns PS00104 EPSP synthase signature 1. 101 115 - T 29-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 GBCGDNIH2_RS10555 69e1e4f879d15749aac9a4616bae185f 454 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 28 449 7.7E-117 T 29-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 GBCGDNIH2_RS10555 69e1e4f879d15749aac9a4616bae185f 454 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 22 450 30.818 T 29-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 GBCGDNIH2_RS10555 69e1e4f879d15749aac9a4616bae185f 454 ProSitePatterns PS00885 EPSP synthase signature 2. 359 377 - T 29-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 GBCGDNIH2_RS10555 69e1e4f879d15749aac9a4616bae185f 454 PIRSF PIRSF000505 16 454 1.1E-115 T 29-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 GBCGDNIH2_RS10555 69e1e4f879d15749aac9a4616bae185f 454 Gene3D G3DSA:3.65.10.10 33 237 1.6E-45 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 GBCGDNIH2_RS10555 69e1e4f879d15749aac9a4616bae185f 454 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 27 441 7.4E-101 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 GBCGDNIH2_RS10555 69e1e4f879d15749aac9a4616bae185f 454 SUPERFAMILY SSF55205 25 450 3.43E-121 T 29-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 GBCGDNIH2_RS03995 e87121a759eeabf5c40098d4ad9aef83 344 SUPERFAMILY SSF54211 39 178 1.75E-16 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold GBCGDNIH2_RS03995 e87121a759eeabf5c40098d4ad9aef83 344 Gene3D G3DSA:3.30.70.890 193 344 1.6E-10 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain GBCGDNIH2_RS03995 e87121a759eeabf5c40098d4ad9aef83 344 Pfam PF00288 GHMP kinases N terminal domain 109 169 1.0E-5 T 29-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 GBCGDNIH2_RS03995 e87121a759eeabf5c40098d4ad9aef83 344 Pfam PF08544 GHMP kinases C terminal 240 324 2.3E-5 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain GBCGDNIH2_RS03995 e87121a759eeabf5c40098d4ad9aef83 344 TIGRFAM TIGR00144 beta_RFAP_syn: beta-ribofuranosylaminobenzene 5'-phosphate synthase family 40 341 5.8E-39 T 29-03-2018 IPR004422 GHMP kinase group 1 MetaCyc: PWY-6148 GBCGDNIH2_RS03995 e87121a759eeabf5c40098d4ad9aef83 344 Gene3D G3DSA:3.30.230.10 37 182 3.6E-13 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup GBCGDNIH2_RS03995 e87121a759eeabf5c40098d4ad9aef83 344 PIRSF PIRSF004884 35 344 5.1E-84 T 29-03-2018 IPR004422 GHMP kinase group 1 MetaCyc: PWY-6148 GBCGDNIH2_RS01525 b002fd753af22a26ddd11b72d6ff51da 79 Gene3D G3DSA:1.10.3990.20 1 79 9.4E-21 T 29-03-2018 GBCGDNIH2_RS01525 b002fd753af22a26ddd11b72d6ff51da 79 Pfam PF13467 Ribbon-helix-helix domain 4 65 2.3E-22 T 29-03-2018 IPR027373 Ribbon-helix-helix domain GBCGDNIH2_RS11350 1a25eb3bf6d268e7961f36e0e81a1605 462 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 72 366 6.1E-81 T 29-03-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 GBCGDNIH2_RS11350 1a25eb3bf6d268e7961f36e0e81a1605 462 PIRSF PIRSF017901 1 461 6.8E-183 T 29-03-2018 IPR035434 Glutamate--cysteine ligase, bacteria and plant GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 GBCGDNIH2_RS11350 1a25eb3bf6d268e7961f36e0e81a1605 462 SUPERFAMILY SSF55931 75 273 1.28E-59 T 29-03-2018 GBCGDNIH2_RS11350 1a25eb3bf6d268e7961f36e0e81a1605 462 SUPERFAMILY SSF55931 316 446 1.28E-59 T 29-03-2018 GBCGDNIH2_RS11350 1a25eb3bf6d268e7961f36e0e81a1605 462 SUPERFAMILY SSF55931 24 47 1.28E-59 T 29-03-2018 GBCGDNIH2_RS11350 1a25eb3bf6d268e7961f36e0e81a1605 462 TIGRFAM TIGR01436 glu_cys_lig_pln: glutamate--cysteine ligase 11 459 9.4E-164 T 29-03-2018 IPR011556 Glutamate--cysteine ligase, plant-type GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 GBCGDNIH2_RS00880 8c1560891ffa1724bd78d236af0f5583 1006 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 285 303 7.3E-9 T 29-03-2018 GBCGDNIH2_RS00880 8c1560891ffa1724bd78d236af0f5583 1006 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 176 195 7.3E-9 T 29-03-2018 GBCGDNIH2_RS00880 8c1560891ffa1724bd78d236af0f5583 1006 PIRSF PIRSF037980 5 1006 0.0 T 29-03-2018 IPR006277 Sarcosine oxidase, alpha subunit GO:0008115|GO:0046653 KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 GBCGDNIH2_RS00880 8c1560891ffa1724bd78d236af0f5583 1006 SUPERFAMILY SSF101790 911 1003 4.09E-13 T 29-03-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain GBCGDNIH2_RS00880 8c1560891ffa1724bd78d236af0f5583 1006 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 888 992 6.6E-8 T 29-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 GBCGDNIH2_RS00880 8c1560891ffa1724bd78d236af0f5583 1006 Gene3D G3DSA:3.50.50.60 353 550 1.1E-8 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS00880 8c1560891ffa1724bd78d236af0f5583 1006 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 23 105 7.2E-26 T 29-03-2018 GBCGDNIH2_RS00880 8c1560891ffa1724bd78d236af0f5583 1006 SUPERFAMILY SSF51905 146 482 2.78E-35 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS00880 8c1560891ffa1724bd78d236af0f5583 1006 Gene3D G3DSA:3.30.1360.120 610 744 1.6E-27 T 29-03-2018 GBCGDNIH2_RS00880 8c1560891ffa1724bd78d236af0f5583 1006 Gene3D G3DSA:2.40.30.110 903 1006 3.4E-15 T 29-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 GBCGDNIH2_RS00880 8c1560891ffa1724bd78d236af0f5583 1006 Pfam PF12831 FAD dependent oxidoreductase 175 213 8.7E-11 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS00880 8c1560891ffa1724bd78d236af0f5583 1006 Pfam PF01571 Aminomethyltransferase folate-binding domain 614 877 4.9E-62 T 29-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal GBCGDNIH2_RS00880 8c1560891ffa1724bd78d236af0f5583 1006 TIGRFAM TIGR01372 soxA: sarcosine oxidase, alpha subunit family 7 1005 0.0 T 29-03-2018 IPR006277 Sarcosine oxidase, alpha subunit GO:0008115|GO:0046653 KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 GBCGDNIH2_RS00880 8c1560891ffa1724bd78d236af0f5583 1006 SUPERFAMILY SSF103025 607 883 5.02E-76 T 29-03-2018 GBCGDNIH2_RS00880 8c1560891ffa1724bd78d236af0f5583 1006 Gene3D G3DSA:3.30.1360.120 745 860 5.3E-17 T 29-03-2018 GBCGDNIH2_RS00880 8c1560891ffa1724bd78d236af0f5583 1006 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 175 197 6.8E-9 T 29-03-2018 GBCGDNIH2_RS00880 8c1560891ffa1724bd78d236af0f5583 1006 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 288 297 6.8E-9 T 29-03-2018 GBCGDNIH2_RS00880 8c1560891ffa1724bd78d236af0f5583 1006 Gene3D G3DSA:3.50.50.60 162 352 8.6E-22 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS02955 8e56266a997b970b29673039aab167d4 339 SUPERFAMILY SSF56553 57 178 2.09E-43 T 29-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GBCGDNIH2_RS02955 8e56266a997b970b29673039aab167d4 339 SUPERFAMILY SSF55257 153 237 5.36E-30 T 29-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GBCGDNIH2_RS02955 8e56266a997b970b29673039aab167d4 339 SUPERFAMILY SSF55257 14 61 5.36E-30 T 29-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GBCGDNIH2_RS02955 8e56266a997b970b29673039aab167d4 339 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 253 310 1.8E-25 T 29-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GBCGDNIH2_RS02955 8e56266a997b970b29673039aab167d4 339 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 63 159 1.5E-21 T 29-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GBCGDNIH2_RS02955 8e56266a997b970b29673039aab167d4 339 SMART SM00662 27 234 1.1E-96 T 29-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GBCGDNIH2_RS02955 8e56266a997b970b29673039aab167d4 339 Gene3D G3DSA:1.10.150.20 248 330 1.4E-27 T 29-03-2018 GBCGDNIH2_RS02955 8e56266a997b970b29673039aab167d4 339 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 7 319 36.206 T 29-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GBCGDNIH2_RS02955 8e56266a997b970b29673039aab167d4 339 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 259 330 1.0E-32 T 29-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GBCGDNIH2_RS02955 8e56266a997b970b29673039aab167d4 339 SUPERFAMILY SSF47789 253 328 4.32E-27 T 29-03-2018 GBCGDNIH2_RS02955 8e56266a997b970b29673039aab167d4 339 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 33 228 1.2E-22 T 29-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GBCGDNIH2_RS02955 8e56266a997b970b29673039aab167d4 339 Gene3D G3DSA:3.30.1360.10 116 231 3.2E-25 T 29-03-2018 GBCGDNIH2_RS02955 8e56266a997b970b29673039aab167d4 339 Gene3D G3DSA:3.30.1360.10 6 92 9.1E-18 T 29-03-2018 GBCGDNIH2_RS02955 8e56266a997b970b29673039aab167d4 339 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 28 318 5.6E-117 T 29-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GBCGDNIH2_RS09180 a5846c84f4e1cdf033171e245544f54a 786 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 227 358 2.2E-11 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 GBCGDNIH2_RS09180 a5846c84f4e1cdf033171e245544f54a 786 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 669 749 1.3E-24 T 29-03-2018 IPR019489 Clp ATPase, C-terminal GBCGDNIH2_RS09180 a5846c84f4e1cdf033171e245544f54a 786 SMART SM01086 669 758 3.0E-37 T 29-03-2018 IPR019489 Clp ATPase, C-terminal GBCGDNIH2_RS09180 a5846c84f4e1cdf033171e245544f54a 786 TIGRFAM TIGR02639 ClpA: ATP-dependent Clp protease ATP-binding subunit ClpA 3 750 0.0 T 29-03-2018 IPR013461 ATP-dependent Clp protease ATP-binding subunit ClpA GO:0004176 GBCGDNIH2_RS09180 a5846c84f4e1cdf033171e245544f54a 786 SUPERFAMILY SSF52540 453 752 1.38E-76 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS09180 a5846c84f4e1cdf033171e245544f54a 786 SUPERFAMILY SSF52540 183 435 2.6E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS09180 a5846c84f4e1cdf033171e245544f54a 786 Pfam PF07724 AAA domain (Cdc48 subfamily) 502 662 6.6E-45 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 GBCGDNIH2_RS09180 a5846c84f4e1cdf033171e245544f54a 786 Gene3D G3DSA:3.40.50.300 181 366 1.4E-25 T 29-03-2018 GBCGDNIH2_RS09180 a5846c84f4e1cdf033171e245544f54a 786 Gene3D G3DSA:1.10.8.60 669 768 9.9E-24 T 29-03-2018 GBCGDNIH2_RS09180 a5846c84f4e1cdf033171e245544f54a 786 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 13 62 4.9E-13 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 GBCGDNIH2_RS09180 a5846c84f4e1cdf033171e245544f54a 786 Gene3D G3DSA:3.40.50.300 458 668 1.1E-43 T 29-03-2018 GBCGDNIH2_RS09180 a5846c84f4e1cdf033171e245544f54a 786 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 318 330 - T 29-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 GBCGDNIH2_RS09180 a5846c84f4e1cdf033171e245544f54a 786 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 534 552 - T 29-03-2018 IPR028299 ClpA/B, conserved site 2 GBCGDNIH2_RS09180 a5846c84f4e1cdf033171e245544f54a 786 SMART SM00382 222 367 1.3E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS09180 a5846c84f4e1cdf033171e245544f54a 786 SMART SM00382 503 670 1.7E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS09180 a5846c84f4e1cdf033171e245544f54a 786 SUPERFAMILY SSF81923 1 141 4.71E-57 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 GBCGDNIH2_RS09180 a5846c84f4e1cdf033171e245544f54a 786 Gene3D G3DSA:1.10.1780.10 1 142 2.4E-25 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 GBCGDNIH2_RS09180 a5846c84f4e1cdf033171e245544f54a 786 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 578 596 1.5E-36 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 GBCGDNIH2_RS09180 a5846c84f4e1cdf033171e245544f54a 786 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 611 625 1.5E-36 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 GBCGDNIH2_RS09180 a5846c84f4e1cdf033171e245544f54a 786 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 507 525 1.5E-36 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 GBCGDNIH2_RS09180 a5846c84f4e1cdf033171e245544f54a 786 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 549 567 1.5E-36 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 GBCGDNIH2_RS09180 a5846c84f4e1cdf033171e245544f54a 786 Gene3D G3DSA:1.10.8.60 367 453 4.8E-25 T 29-03-2018 GBCGDNIH2_RS06140 8a14c36090f847e8b819b877d73dd12c 257 Pfam PF00588 SpoU rRNA Methylase family 18 168 8.0E-26 T 29-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 GBCGDNIH2_RS06140 8a14c36090f847e8b819b877d73dd12c 257 PIRSF PIRSF004808 13 254 1.6E-74 T 29-03-2018 IPR004384 RNA methyltransferase TrmH, group 1 GO:0006396|GO:0008173 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 GBCGDNIH2_RS06140 8a14c36090f847e8b819b877d73dd12c 257 Gene3D G3DSA:3.40.1280.10 11 179 4.2E-33 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal GBCGDNIH2_RS06140 8a14c36090f847e8b819b877d73dd12c 257 SUPERFAMILY SSF75217 11 178 1.9E-32 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases GBCGDNIH2_RS07330 9d012cb3af4cc2c51551a40cb506f20e 880 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 6 861 1.1E-287 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 GBCGDNIH2_RS07330 9d012cb3af4cc2c51551a40cb506f20e 880 SUPERFAMILY SSF55681 3 245 4.47E-108 T 29-03-2018 GBCGDNIH2_RS07330 9d012cb3af4cc2c51551a40cb506f20e 880 SUPERFAMILY SSF101353 246 461 5.62E-58 T 29-03-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 GBCGDNIH2_RS07330 9d012cb3af4cc2c51551a40cb506f20e 880 SMART SM00863 654 705 2.8E-22 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 GBCGDNIH2_RS07330 9d012cb3af4cc2c51551a40cb506f20e 880 SUPERFAMILY SSF50447 453 553 2.31E-19 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain GBCGDNIH2_RS07330 9d012cb3af4cc2c51551a40cb506f20e 880 SUPERFAMILY SSF55186 553 716 4.32E-48 T 29-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 GBCGDNIH2_RS07330 9d012cb3af4cc2c51551a40cb506f20e 880 Gene3D G3DSA:3.30.930.10 1 242 3.9E-111 T 29-03-2018 GBCGDNIH2_RS07330 9d012cb3af4cc2c51551a40cb506f20e 880 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 654 705 9.6E-18 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 GBCGDNIH2_RS07330 9d012cb3af4cc2c51551a40cb506f20e 880 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 880 194.503 T 29-03-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 GBCGDNIH2_RS07330 9d012cb3af4cc2c51551a40cb506f20e 880 Pfam PF01411 tRNA synthetases class II (A) 6 557 2.3E-212 T 29-03-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 GBCGDNIH2_RS07330 9d012cb3af4cc2c51551a40cb506f20e 880 Gene3D G3DSA:3.30.980.10 554 722 1.9E-44 T 29-03-2018 GBCGDNIH2_RS07330 9d012cb3af4cc2c51551a40cb506f20e 880 PRINTS PR00980 Alanyl-tRNA synthetase signature 199 210 2.8E-32 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 GBCGDNIH2_RS07330 9d012cb3af4cc2c51551a40cb506f20e 880 PRINTS PR00980 Alanyl-tRNA synthetase signature 75 86 2.8E-32 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 GBCGDNIH2_RS07330 9d012cb3af4cc2c51551a40cb506f20e 880 PRINTS PR00980 Alanyl-tRNA synthetase signature 226 239 2.8E-32 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 GBCGDNIH2_RS07330 9d012cb3af4cc2c51551a40cb506f20e 880 PRINTS PR00980 Alanyl-tRNA synthetase signature 274 290 2.8E-32 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 GBCGDNIH2_RS07330 9d012cb3af4cc2c51551a40cb506f20e 880 PRINTS PR00980 Alanyl-tRNA synthetase signature 298 311 2.8E-32 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 GBCGDNIH2_RS07330 9d012cb3af4cc2c51551a40cb506f20e 880 Pfam PF02272 DHHA1 domain 742 877 3.0E-20 T 29-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 GBCGDNIH2_RS08670 17eeee3e24c295c0782535b1d8c6fe94 427 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 241 359 9.9E-10 T 29-03-2018 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 GBCGDNIH2_RS08670 17eeee3e24c295c0782535b1d8c6fe94 427 Gene3D G3DSA:3.40.50.2000 231 417 9.1E-27 T 29-03-2018 GBCGDNIH2_RS08670 17eeee3e24c295c0782535b1d8c6fe94 427 TIGRFAM TIGR04414 hepto_Aah_TibC: autotransporter strand-loop-strand O-heptosyltransferase 29 413 1.1E-188 T 29-03-2018 IPR030929 Glycosyltransferase Aah/TibC GO:0016757 GBCGDNIH2_RS08670 17eeee3e24c295c0782535b1d8c6fe94 427 SUPERFAMILY SSF53756 127 412 1.76E-22 T 29-03-2018 GBCGDNIH2_RS05055 e09beff79c0f43766edd90b4b5703246 459 Gene3D G3DSA:3.40.640.10 56 319 7.1E-36 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GBCGDNIH2_RS05055 e09beff79c0f43766edd90b4b5703246 459 TIGRFAM TIGR01788 Glu-decarb-GAD: glutamate decarboxylase 9 438 4.0E-189 T 29-03-2018 IPR010107 Glutamate decarboxylase GO:0004351|GO:0006536|GO:0030170 KEGG: 00250+4.1.1.15|KEGG: 00410+4.1.1.15|KEGG: 00430+4.1.1.15|KEGG: 00650+4.1.1.15|MetaCyc: PWY-4321 GBCGDNIH2_RS05055 e09beff79c0f43766edd90b4b5703246 459 Gene3D G3DSA:3.90.1150.10 320 437 2.5E-21 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 GBCGDNIH2_RS05055 e09beff79c0f43766edd90b4b5703246 459 SUPERFAMILY SSF53383 2 442 1.47E-134 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase GBCGDNIH2_RS05055 e09beff79c0f43766edd90b4b5703246 459 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 39 372 7.8E-87 T 29-03-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 GBCGDNIH2_RS09985 dfa5a8c1f5b04735bcdf348423102080 235 SUPERFAMILY SSF161098 37 221 2.75E-31 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GBCGDNIH2_RS09985 dfa5a8c1f5b04735bcdf348423102080 235 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 61 219 7.9E-18 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GBCGDNIH2_RS09985 dfa5a8c1f5b04735bcdf348423102080 235 Gene3D G3DSA:1.10.3720.10 2 235 2.1E-25 T 29-03-2018 GBCGDNIH2_RS06970 d5cfd106c3bbfdffa1df4869d78fe47f 194 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 46 187 2.1E-77 T 29-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS06970 d5cfd106c3bbfdffa1df4869d78fe47f 194 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 35 186 42.382 T 29-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS06970 d5cfd106c3bbfdffa1df4869d78fe47f 194 Gene3D G3DSA:3.40.50.700 45 190 6.3E-51 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS06970 d5cfd106c3bbfdffa1df4869d78fe47f 194 SUPERFAMILY SSF56770 44 188 2.49E-68 T 29-03-2018 GBCGDNIH2_RS06970 d5cfd106c3bbfdffa1df4869d78fe47f 194 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 153 169 - T 29-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS06970 d5cfd106c3bbfdffa1df4869d78fe47f 194 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 73 181 1.2E-22 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS07555 38ea199baf6487dceecc21218cfc8ad5 364 Pfam PF10005 zinc-ribbon domain 3 98 1.7E-32 T 29-03-2018 IPR011201 Zinc-ribbon domain, bacteria GBCGDNIH2_RS07555 38ea199baf6487dceecc21218cfc8ad5 364 Pfam PF15887 Putative zinc-binding metallo-peptidase 102 347 3.4E-107 T 29-03-2018 IPR031321 Uncharacterised conserved protein UCP012641, putative zinc-binding metallo-peptidase GBCGDNIH2_RS07555 38ea199baf6487dceecc21218cfc8ad5 364 PIRSF PIRSF012641 1 363 2.9E-144 T 29-03-2018 IPR031321 Uncharacterised conserved protein UCP012641, putative zinc-binding metallo-peptidase GBCGDNIH2_RS07555 38ea199baf6487dceecc21218cfc8ad5 364 Gene3D G3DSA:3.40.390.10 101 285 1.5E-16 T 29-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 GBCGDNIH2_RS07025 674f2fc24391d93d9dcf4f5cfa224653 215 Gene3D G3DSA:3.90.226.10 13 205 1.9E-49 T 29-03-2018 GBCGDNIH2_RS07025 674f2fc24391d93d9dcf4f5cfa224653 215 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 14 204 42.999 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 GBCGDNIH2_RS07025 674f2fc24391d93d9dcf4f5cfa224653 215 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 13 203 5.5E-95 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 GBCGDNIH2_RS07025 674f2fc24391d93d9dcf4f5cfa224653 215 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 123 136 - T 29-03-2018 IPR033135 ClpP, histidine active site GBCGDNIH2_RS07025 674f2fc24391d93d9dcf4f5cfa224653 215 Pfam PF00574 Clp protease 24 203 9.7E-85 T 29-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA GBCGDNIH2_RS07025 674f2fc24391d93d9dcf4f5cfa224653 215 PRINTS PR00127 Clp protease catalytic subunit P signature 70 90 1.2E-50 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 GBCGDNIH2_RS07025 674f2fc24391d93d9dcf4f5cfa224653 215 PRINTS PR00127 Clp protease catalytic subunit P signature 179 198 1.2E-50 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 GBCGDNIH2_RS07025 674f2fc24391d93d9dcf4f5cfa224653 215 PRINTS PR00127 Clp protease catalytic subunit P signature 30 45 1.2E-50 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 GBCGDNIH2_RS07025 674f2fc24391d93d9dcf4f5cfa224653 215 PRINTS PR00127 Clp protease catalytic subunit P signature 122 141 1.2E-50 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 GBCGDNIH2_RS07025 674f2fc24391d93d9dcf4f5cfa224653 215 PRINTS PR00127 Clp protease catalytic subunit P signature 101 118 1.2E-50 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 GBCGDNIH2_RS07025 674f2fc24391d93d9dcf4f5cfa224653 215 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 101 112 - T 29-03-2018 IPR018215 ClpP, Ser active site GBCGDNIH2_RS07025 674f2fc24391d93d9dcf4f5cfa224653 215 SUPERFAMILY SSF52096 22 205 8.22E-72 T 29-03-2018 IPR029045 ClpP/crotonase-like domain GBCGDNIH2_RS05270 f0e09295d5001add8d85bb0c1e3cfe2d 284 Gene3D G3DSA:3.40.250.10 159 283 9.8E-26 T 29-03-2018 IPR001763 Rhodanese-like domain GBCGDNIH2_RS05270 f0e09295d5001add8d85bb0c1e3cfe2d 284 Pfam PF00581 Rhodanese-like domain 160 272 7.8E-11 T 29-03-2018 IPR001763 Rhodanese-like domain GBCGDNIH2_RS05270 f0e09295d5001add8d85bb0c1e3cfe2d 284 Pfam PF00581 Rhodanese-like domain 10 127 1.2E-14 T 29-03-2018 IPR001763 Rhodanese-like domain GBCGDNIH2_RS05270 f0e09295d5001add8d85bb0c1e3cfe2d 284 SMART SM00450 156 277 2.4E-15 T 29-03-2018 IPR001763 Rhodanese-like domain GBCGDNIH2_RS05270 f0e09295d5001add8d85bb0c1e3cfe2d 284 SMART SM00450 8 131 1.8E-20 T 29-03-2018 IPR001763 Rhodanese-like domain GBCGDNIH2_RS05270 f0e09295d5001add8d85bb0c1e3cfe2d 284 SUPERFAMILY SSF52821 160 277 1.83E-32 T 29-03-2018 IPR001763 Rhodanese-like domain GBCGDNIH2_RS05270 f0e09295d5001add8d85bb0c1e3cfe2d 284 Gene3D G3DSA:3.40.250.10 1 149 6.6E-31 T 29-03-2018 IPR001763 Rhodanese-like domain GBCGDNIH2_RS05270 f0e09295d5001add8d85bb0c1e3cfe2d 284 SUPERFAMILY SSF52821 5 143 1.83E-43 T 29-03-2018 IPR001763 Rhodanese-like domain GBCGDNIH2_RS05270 f0e09295d5001add8d85bb0c1e3cfe2d 284 ProSitePatterns PS00380 Rhodanese signature 1. 42 53 - T 29-03-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 GBCGDNIH2_RS05270 f0e09295d5001add8d85bb0c1e3cfe2d 284 ProSitePatterns PS00683 Rhodanese C-terminal signature. 261 271 - T 29-03-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 GBCGDNIH2_RS11450 20868f382380d189017d1a559812afa1 429 Pfam PF02618 YceG-like family 149 421 1.6E-71 T 29-03-2018 IPR003770 Endolytic murein transglycosylase GBCGDNIH2_RS11450 20868f382380d189017d1a559812afa1 429 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 116 424 31.428 T 29-03-2018 IPR003770 Endolytic murein transglycosylase GBCGDNIH2_RS11450 20868f382380d189017d1a559812afa1 429 Gene3D G3DSA:3.30.160.60 396 429 2.6E-12 T 29-03-2018 GBCGDNIH2_RS11450 20868f382380d189017d1a559812afa1 429 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 247 422 2.4E-52 T 29-03-2018 IPR003770 Endolytic murein transglycosylase GBCGDNIH2_RS04375 c806c105b16706eccbb7f17025863dab 267 Gene3D G3DSA:3.40.50.1000 78 266 3.3E-24 T 29-03-2018 IPR023214 HAD-like domain GBCGDNIH2_RS04375 c806c105b16706eccbb7f17025863dab 267 SUPERFAMILY SSF56784 3 266 1.58E-67 T 29-03-2018 IPR023214 HAD-like domain GBCGDNIH2_RS04375 c806c105b16706eccbb7f17025863dab 267 ProSitePatterns PS01229 Hypothetical cof family signature 2. 215 237 - T 29-03-2018 GBCGDNIH2_RS04375 c806c105b16706eccbb7f17025863dab 267 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 7 234 8.8E-27 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 GBCGDNIH2_RS04375 c806c105b16706eccbb7f17025863dab 267 Pfam PF08282 haloacid dehalogenase-like hydrolase 8 261 6.9E-62 T 29-03-2018 IPR023214 HAD-like domain GBCGDNIH2_RS04375 c806c105b16706eccbb7f17025863dab 267 Gene3D G3DSA:3.40.50.1000 1 77 7.9E-11 T 29-03-2018 IPR023214 HAD-like domain GBCGDNIH2_RS04375 c806c105b16706eccbb7f17025863dab 267 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 8 261 7.1E-58 T 29-03-2018 IPR000150 Cof family GO:0016787 GBCGDNIH2_RS10765 5713d71f7c4283d83227feddfaacb273 447 SUPERFAMILY SSF52777 216 445 2.89E-88 T 29-03-2018 GBCGDNIH2_RS10765 5713d71f7c4283d83227feddfaacb273 447 Gene3D G3DSA:3.90.1170.30 45 91 0.2 T 29-03-2018 GBCGDNIH2_RS10765 5713d71f7c4283d83227feddfaacb273 447 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 GBCGDNIH2_RS10765 5713d71f7c4283d83227feddfaacb273 447 SUPERFAMILY SSF47005 151 192 2.62E-6 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 GBCGDNIH2_RS10765 5713d71f7c4283d83227feddfaacb273 447 TIGRFAM TIGR01347 sucB: dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex 4 446 3.0E-164 T 29-03-2018 IPR006255 Dihydrolipoamide succinyltransferase GO:0004149|GO:0006099|GO:0045252 KEGG: 00020+2.3.1.61|KEGG: 00310+2.3.1.61|MetaCyc: PWY-5084|Reactome: R-HSA-389661|Reactome: R-HSA-71064|Reactome: R-HSA-71403 GBCGDNIH2_RS10765 5713d71f7c4283d83227feddfaacb273 447 Gene3D G3DSA:4.10.320.10 149 200 1.6E-12 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 GBCGDNIH2_RS10765 5713d71f7c4283d83227feddfaacb273 447 SUPERFAMILY SSF51230 1 96 9.42E-26 T 29-03-2018 IPR011053 Single hybrid motif GBCGDNIH2_RS10765 5713d71f7c4283d83227feddfaacb273 447 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 216 445 9.1E-80 T 29-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 GBCGDNIH2_RS10765 5713d71f7c4283d83227feddfaacb273 447 Gene3D G3DSA:3.30.559.10 201 445 2.3E-91 T 29-03-2018 GBCGDNIH2_RS10765 5713d71f7c4283d83227feddfaacb273 447 Gene3D G3DSA:3.90.1170.30 2 44 5.7E-14 T 29-03-2018 GBCGDNIH2_RS10765 5713d71f7c4283d83227feddfaacb273 447 Pfam PF02817 e3 binding domain 156 188 2.0E-9 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 GBCGDNIH2_RS10765 5713d71f7c4283d83227feddfaacb273 447 Pfam PF00364 Biotin-requiring enzyme 4 76 6.6E-19 T 29-03-2018 IPR000089 Biotin/lipoyl attachment GBCGDNIH2_RS09610 bbced53bc418b10b9831d8d4880122bf 416 TIGRFAM TIGR03407 urea_ABC_UrtA: urea ABC transporter, urea binding protein 52 411 1.3E-162 T 29-03-2018 IPR017777 Urea ABC transporter, substrate-binding protein UrtA-like GBCGDNIH2_RS09610 bbced53bc418b10b9831d8d4880122bf 416 SUPERFAMILY SSF53822 51 412 6.73E-94 T 29-03-2018 IPR028082 Periplasmic binding protein-like I GBCGDNIH2_RS09610 bbced53bc418b10b9831d8d4880122bf 416 Pfam PF13433 Periplasmic binding protein domain 53 413 1.6E-132 T 29-03-2018 GBCGDNIH2_RS09610 bbced53bc418b10b9831d8d4880122bf 416 Gene3D G3DSA:3.40.50.2300 176 354 5.6E-34 T 29-03-2018 GBCGDNIH2_RS09610 bbced53bc418b10b9831d8d4880122bf 416 Gene3D G3DSA:3.40.50.2300 43 175 4.2E-22 T 29-03-2018 GBCGDNIH2_RS07850 f1c1efea220414eb8e1e699fb9f834a0 4713 SUPERFAMILY SSF51294 4511 4644 7.85E-14 T 29-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 GBCGDNIH2_RS07850 f1c1efea220414eb8e1e699fb9f834a0 4713 Pfam PF13403 Hint domain 4510 4645 1.3E-46 T 29-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 GBCGDNIH2_RS07850 f1c1efea220414eb8e1e699fb9f834a0 4713 Gene3D G3DSA:2.170.16.10 4503 4702 2.0E-17 T 29-03-2018 GBCGDNIH2_RS07850 f1c1efea220414eb8e1e699fb9f834a0 4713 SMART SM00710 3754 3773 5600.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat GBCGDNIH2_RS07850 f1c1efea220414eb8e1e699fb9f834a0 4713 SMART SM00710 998 1025 1700.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat GBCGDNIH2_RS07850 f1c1efea220414eb8e1e699fb9f834a0 4713 SMART SM00710 3388 3411 5100.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat GBCGDNIH2_RS07850 f1c1efea220414eb8e1e699fb9f834a0 4713 SMART SM00710 3413 3434 7200.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat GBCGDNIH2_RS07850 f1c1efea220414eb8e1e699fb9f834a0 4713 SMART SM00710 2544 2568 1900.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat GBCGDNIH2_RS07850 f1c1efea220414eb8e1e699fb9f834a0 4713 SMART SM00710 2810 2837 2300.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat GBCGDNIH2_RS07850 f1c1efea220414eb8e1e699fb9f834a0 4713 SMART SM00710 2986 3017 6600.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat GBCGDNIH2_RS07850 f1c1efea220414eb8e1e699fb9f834a0 4713 SMART SM00710 522 546 1900.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat GBCGDNIH2_RS07850 f1c1efea220414eb8e1e699fb9f834a0 4713 SMART SM00710 2276 2303 2200.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat GBCGDNIH2_RS07850 f1c1efea220414eb8e1e699fb9f834a0 4713 SMART SM00710 1266 1290 1900.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat GBCGDNIH2_RS07850 f1c1efea220414eb8e1e699fb9f834a0 4713 SMART SM00710 254 281 2000.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat GBCGDNIH2_RS07850 f1c1efea220414eb8e1e699fb9f834a0 4713 SMART SM00710 2599 2621 7400.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat GBCGDNIH2_RS07850 f1c1efea220414eb8e1e699fb9f834a0 4713 SMART SM00710 2010 2034 1900.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat GBCGDNIH2_RS07850 f1c1efea220414eb8e1e699fb9f834a0 4713 SMART SM00710 1321 1343 7400.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat GBCGDNIH2_RS07850 f1c1efea220414eb8e1e699fb9f834a0 4713 SMART SM00710 3315 3342 9500.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat GBCGDNIH2_RS07850 f1c1efea220414eb8e1e699fb9f834a0 4713 SMART SM00710 577 599 7400.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat GBCGDNIH2_RS07850 f1c1efea220414eb8e1e699fb9f834a0 4713 SMART SM00710 3941 3968 1700.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat GBCGDNIH2_RS07850 f1c1efea220414eb8e1e699fb9f834a0 4713 SMART SM00710 2065 2087 7400.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat GBCGDNIH2_RS07850 f1c1efea220414eb8e1e699fb9f834a0 4713 SMART SM00710 3070 3093 9500.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat GBCGDNIH2_RS07850 f1c1efea220414eb8e1e699fb9f834a0 4713 SMART SM00710 784 805 1600.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat GBCGDNIH2_RS07850 f1c1efea220414eb8e1e699fb9f834a0 4713 SMART SM00710 1742 1769 1700.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat GBCGDNIH2_RS07850 f1c1efea220414eb8e1e699fb9f834a0 4713 SMART SM00710 735 757 1600.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat GBCGDNIH2_RS07850 f1c1efea220414eb8e1e699fb9f834a0 4713 SMART SM00710 1528 1549 1600.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat GBCGDNIH2_RS07850 f1c1efea220414eb8e1e699fb9f834a0 4713 SMART SM00710 1479 1501 1600.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat GBCGDNIH2_RS04380 0692611f4c4ed87f280d406d98d0cc13 512 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 20 509 78.317 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 GBCGDNIH2_RS04380 0692611f4c4ed87f280d406d98d0cc13 512 SUPERFAMILY SSF51735 11 211 6.1E-54 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS04380 0692611f4c4ed87f280d406d98d0cc13 512 PIRSF PIRSF000110 4 511 2.9E-166 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 GBCGDNIH2_RS04380 0692611f4c4ed87f280d406d98d0cc13 512 Gene3D G3DSA:3.30.360.10 210 510 6.3E-124 T 29-03-2018 GBCGDNIH2_RS04380 0692611f4c4ed87f280d406d98d0cc13 512 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 210 508 8.1E-113 T 29-03-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 GBCGDNIH2_RS04380 0692611f4c4ed87f280d406d98d0cc13 512 SUPERFAMILY SSF55347 203 508 7.19E-112 T 29-03-2018 GBCGDNIH2_RS04380 0692611f4c4ed87f280d406d98d0cc13 512 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 198 204 - T 29-03-2018 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 GBCGDNIH2_RS04380 0692611f4c4ed87f280d406d98d0cc13 512 Gene3D G3DSA:3.40.50.720 18 209 9.5E-61 T 29-03-2018 GBCGDNIH2_RS04380 0692611f4c4ed87f280d406d98d0cc13 512 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 24 208 1.4E-56 T 29-03-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 GBCGDNIH2_RS04380 0692611f4c4ed87f280d406d98d0cc13 512 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 164 177 8.7E-45 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 GBCGDNIH2_RS04380 0692611f4c4ed87f280d406d98d0cc13 512 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 258 274 8.7E-45 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 GBCGDNIH2_RS04380 0692611f4c4ed87f280d406d98d0cc13 512 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 188 216 8.7E-45 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 GBCGDNIH2_RS04380 0692611f4c4ed87f280d406d98d0cc13 512 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 240 257 8.7E-45 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 GBCGDNIH2_RS04380 0692611f4c4ed87f280d406d98d0cc13 512 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 349 375 8.7E-45 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 GBCGDNIH2_RS04380 0692611f4c4ed87f280d406d98d0cc13 512 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 20 509 5.7E-180 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 GBCGDNIH2_RS03420 fca60a9297d98e11e388d9f995ca9b9e 249 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 249 38.359 T 29-03-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 GBCGDNIH2_RS03420 fca60a9297d98e11e388d9f995ca9b9e 249 TIGRFAM TIGR00317 cobS: cobalamin 5'-phosphate synthase 10 238 7.8E-39 T 29-03-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 GBCGDNIH2_RS03420 fca60a9297d98e11e388d9f995ca9b9e 249 Pfam PF02654 Cobalamin-5-phosphate synthase 16 242 2.0E-43 T 29-03-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 GBCGDNIH2_RS11680 59578d6a21957783f4a99569758ccf02 443 Pfam PF01523 Putative modulator of DNA gyrase 23 312 5.3E-56 T 29-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 GBCGDNIH2_RS11680 59578d6a21957783f4a99569758ccf02 443 Gene3D G3DSA:3.30.2290.10 2 221 9.1E-49 T 29-03-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal domain GBCGDNIH2_RS11680 59578d6a21957783f4a99569758ccf02 443 SUPERFAMILY SSF111283 3 442 4.19E-118 T 29-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 GBCGDNIH2_RS11635 12e78c94e5ea00ba93deb0cf223c3978 237 Gene3D G3DSA:3.40.1130.10 59 220 1.6E-6 T 29-03-2018 GBCGDNIH2_RS11635 12e78c94e5ea00ba93deb0cf223c3978 237 Pfam PF04028 Domain of unknown function (DUF374) 73 137 2.1E-24 T 29-03-2018 IPR007172 Domain of unknown function DUF374 GBCGDNIH2_RS11635 12e78c94e5ea00ba93deb0cf223c3978 237 ProDom PD032436 LIPOPROTEIN UNCHARACTERIZED PROBABLE CJ0457C SIMILAR TRANSFERASE BACTERIA PRECURSOR SIGNAL CC0304 22 137 2.0E-19 T 29-03-2018 IPR007172 Domain of unknown function DUF374 GBCGDNIH2_RS12560 4c644fab9dab0c41666dcf4369ee63fa 344 Gene3D G3DSA:3.30.160.40 259 342 5.0E-16 T 29-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 GBCGDNIH2_RS12560 4c644fab9dab0c41666dcf4369ee63fa 344 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 33 333 1.2E-90 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 GBCGDNIH2_RS12560 4c644fab9dab0c41666dcf4369ee63fa 344 PIRSF PIRSF001438 14 344 7.8E-104 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 GBCGDNIH2_RS12560 4c644fab9dab0c41666dcf4369ee63fa 344 Gene3D G3DSA:3.40.190.10 137 237 1.4E-32 T 29-03-2018 GBCGDNIH2_RS12560 4c644fab9dab0c41666dcf4369ee63fa 344 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 269 285 - T 29-03-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 GBCGDNIH2_RS12560 4c644fab9dab0c41666dcf4369ee63fa 344 Gene3D G3DSA:3.40.190.10 26 136 1.9E-37 T 29-03-2018 GBCGDNIH2_RS12560 4c644fab9dab0c41666dcf4369ee63fa 344 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 32 336 33.623 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 GBCGDNIH2_RS12560 4c644fab9dab0c41666dcf4369ee63fa 344 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 33 250 6.3E-69 T 29-03-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 GBCGDNIH2_RS12560 4c644fab9dab0c41666dcf4369ee63fa 344 SUPERFAMILY SSF54782 259 342 7.45E-19 T 29-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 GBCGDNIH2_RS12560 4c644fab9dab0c41666dcf4369ee63fa 344 PRINTS PR00151 Porphobilinogen deaminase signature 181 198 1.2E-31 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 GBCGDNIH2_RS12560 4c644fab9dab0c41666dcf4369ee63fa 344 PRINTS PR00151 Porphobilinogen deaminase signature 76 96 1.2E-31 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 GBCGDNIH2_RS12560 4c644fab9dab0c41666dcf4369ee63fa 344 PRINTS PR00151 Porphobilinogen deaminase signature 107 126 1.2E-31 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 GBCGDNIH2_RS12560 4c644fab9dab0c41666dcf4369ee63fa 344 PRINTS PR00151 Porphobilinogen deaminase signature 268 285 1.2E-31 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 GBCGDNIH2_RS12560 4c644fab9dab0c41666dcf4369ee63fa 344 SUPERFAMILY SSF53850 32 256 1.85E-65 T 29-03-2018 GBCGDNIH2_RS12560 4c644fab9dab0c41666dcf4369ee63fa 344 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 266 334 2.9E-14 T 29-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 GBCGDNIH2_RS10775 029ccba3e137f50a3489cf2ce6796b15 291 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 3 288 2.0E-136 T 29-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 GBCGDNIH2_RS10775 029ccba3e137f50a3489cf2ce6796b15 291 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 152 181 - T 29-03-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site GBCGDNIH2_RS10775 029ccba3e137f50a3489cf2ce6796b15 291 PIRSF PIRSF001553 1 291 1.4E-129 T 29-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 GBCGDNIH2_RS10775 029ccba3e137f50a3489cf2ce6796b15 291 Pfam PF00549 CoA-ligase 151 272 2.2E-21 T 29-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 GBCGDNIH2_RS10775 029ccba3e137f50a3489cf2ce6796b15 291 Gene3D G3DSA:3.40.50.720 1 119 5.4E-46 T 29-03-2018 GBCGDNIH2_RS10775 029ccba3e137f50a3489cf2ce6796b15 291 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 289 42.446 T 29-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 GBCGDNIH2_RS10775 029ccba3e137f50a3489cf2ce6796b15 291 Gene3D G3DSA:3.40.50.261 120 291 3.8E-56 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 GBCGDNIH2_RS10775 029ccba3e137f50a3489cf2ce6796b15 291 Pfam PF02629 CoA binding domain 8 99 2.7E-28 T 29-03-2018 IPR003781 CoA-binding GO:0048037 GBCGDNIH2_RS10775 029ccba3e137f50a3489cf2ce6796b15 291 PRINTS PR01798 Succinyl-CoA synthase signature 208 221 1.1E-36 T 29-03-2018 GBCGDNIH2_RS10775 029ccba3e137f50a3489cf2ce6796b15 291 PRINTS PR01798 Succinyl-CoA synthase signature 241 258 1.1E-36 T 29-03-2018 GBCGDNIH2_RS10775 029ccba3e137f50a3489cf2ce6796b15 291 PRINTS PR01798 Succinyl-CoA synthase signature 82 99 1.1E-36 T 29-03-2018 GBCGDNIH2_RS10775 029ccba3e137f50a3489cf2ce6796b15 291 PRINTS PR01798 Succinyl-CoA synthase signature 177 195 1.1E-36 T 29-03-2018 GBCGDNIH2_RS10775 029ccba3e137f50a3489cf2ce6796b15 291 SUPERFAMILY SSF52210 123 287 5.49E-54 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 GBCGDNIH2_RS10775 029ccba3e137f50a3489cf2ce6796b15 291 SMART SM00881 4 100 1.6E-32 T 29-03-2018 IPR003781 CoA-binding GO:0048037 GBCGDNIH2_RS10775 029ccba3e137f50a3489cf2ce6796b15 291 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 237 250 - T 29-03-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site GBCGDNIH2_RS10775 029ccba3e137f50a3489cf2ce6796b15 291 SUPERFAMILY SSF51735 1 122 7.89E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS00205 a76cf6acdb439b9f2ea97fd605672ea3 296 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 215 293 4.9E-19 T 29-03-2018 IPR006260 TonB, C-terminal GO:0006810 GBCGDNIH2_RS00205 a76cf6acdb439b9f2ea97fd605672ea3 296 SUPERFAMILY SSF74653 211 282 7.06E-17 T 29-03-2018 GBCGDNIH2_RS00205 a76cf6acdb439b9f2ea97fd605672ea3 296 PRINTS PR01374 Gram-negative bacterial tonB protein signature 153 163 1.0E-6 T 29-03-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 GBCGDNIH2_RS00205 a76cf6acdb439b9f2ea97fd605672ea3 296 PRINTS PR01374 Gram-negative bacterial tonB protein signature 209 230 1.0E-6 T 29-03-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 GBCGDNIH2_RS00205 a76cf6acdb439b9f2ea97fd605672ea3 296 PRINTS PR01374 Gram-negative bacterial tonB protein signature 230 248 1.0E-6 T 29-03-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 GBCGDNIH2_RS00205 a76cf6acdb439b9f2ea97fd605672ea3 296 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 215 292 2.4E-16 T 29-03-2018 IPR006260 TonB, C-terminal GO:0006810 GBCGDNIH2_RS00205 a76cf6acdb439b9f2ea97fd605672ea3 296 Gene3D G3DSA:3.30.1150.10 89 296 1.1E-21 T 29-03-2018 GBCGDNIH2_RS06370 954a47d783f6d9e9d94189954b566dfc 425 SUPERFAMILY SSF51604 139 421 1.5E-122 T 29-03-2018 IPR029065 Enolase C-terminal domain-like GBCGDNIH2_RS06370 954a47d783f6d9e9d94189954b566dfc 425 Pfam PF00113 Enolase, C-terminal TIM barrel domain 141 422 4.7E-125 T 29-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 GBCGDNIH2_RS06370 954a47d783f6d9e9d94189954b566dfc 425 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 421 7.4E-202 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 GBCGDNIH2_RS06370 954a47d783f6d9e9d94189954b566dfc 425 SMART SM01193 4 134 1.4E-91 T 29-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 GBCGDNIH2_RS06370 954a47d783f6d9e9d94189954b566dfc 425 ProSitePatterns PS00164 Enolase signature. 334 347 - T 29-03-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GBCGDNIH2_RS06370 954a47d783f6d9e9d94189954b566dfc 425 SUPERFAMILY SSF54826 4 138 1.85E-55 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 GBCGDNIH2_RS06370 954a47d783f6d9e9d94189954b566dfc 425 Gene3D G3DSA:3.20.20.120 128 424 2.1E-100 T 29-03-2018 IPR029065 Enolase C-terminal domain-like GBCGDNIH2_RS06370 954a47d783f6d9e9d94189954b566dfc 425 Gene3D G3DSA:3.30.390.10 3 127 2.3E-50 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 GBCGDNIH2_RS06370 954a47d783f6d9e9d94189954b566dfc 425 PIRSF PIRSF001400 1 424 2.0E-184 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 GBCGDNIH2_RS06370 954a47d783f6d9e9d94189954b566dfc 425 Pfam PF03952 Enolase, N-terminal domain 4 134 1.1E-57 T 29-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 GBCGDNIH2_RS06370 954a47d783f6d9e9d94189954b566dfc 425 PRINTS PR00148 Enolase signature 37 51 4.2E-45 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 GBCGDNIH2_RS06370 954a47d783f6d9e9d94189954b566dfc 425 PRINTS PR00148 Enolase signature 311 322 4.2E-45 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 GBCGDNIH2_RS06370 954a47d783f6d9e9d94189954b566dfc 425 PRINTS PR00148 Enolase signature 161 174 4.2E-45 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 GBCGDNIH2_RS06370 954a47d783f6d9e9d94189954b566dfc 425 PRINTS PR00148 Enolase signature 334 348 4.2E-45 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 GBCGDNIH2_RS06370 954a47d783f6d9e9d94189954b566dfc 425 PRINTS PR00148 Enolase signature 107 123 4.2E-45 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 GBCGDNIH2_RS06370 954a47d783f6d9e9d94189954b566dfc 425 PRINTS PR00148 Enolase signature 363 380 4.2E-45 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 GBCGDNIH2_RS06370 954a47d783f6d9e9d94189954b566dfc 425 SMART SM01192 139 425 4.2E-211 T 29-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 GBCGDNIH2_RS06370 954a47d783f6d9e9d94189954b566dfc 425 Hamap MF_00318 Enolase [eno]. 2 411 43.579 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 GBCGDNIH2_RS12655 d551db536d7cc25c33ea11b15284d46d 254 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 35 253 2.7E-36 T 29-03-2018 IPR024455 Phage capsid GBCGDNIH2_RS12655 d551db536d7cc25c33ea11b15284d46d 254 Pfam PF05065 Phage capsid family 147 253 1.2E-16 T 29-03-2018 IPR024455 Phage capsid GBCGDNIH2_RS12655 d551db536d7cc25c33ea11b15284d46d 254 SUPERFAMILY SSF56563 141 252 5.62E-18 T 29-03-2018 GBCGDNIH2_RS12655 d551db536d7cc25c33ea11b15284d46d 254 Gene3D G3DSA:3.30.2400.10 168 254 8.6E-13 T 29-03-2018 GBCGDNIH2_RS11110 fa73871851f34d84a53819bd72d61b6c 112 PIRSF PIRSF039144 1 112 3.8E-53 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 GBCGDNIH2_RS11110 fa73871851f34d84a53819bd72d61b6c 112 SMART SM00938 4 105 5.6E-65 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 GBCGDNIH2_RS11110 fa73871851f34d84a53819bd72d61b6c 112 Gene3D G3DSA:3.30.70.120 1 108 1.5E-47 T 29-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal GBCGDNIH2_RS11110 fa73871851f34d84a53819bd72d61b6c 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 29-03-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 GBCGDNIH2_RS11110 fa73871851f34d84a53819bd72d61b6c 112 SUPERFAMILY SSF54913 1 112 2.67E-44 T 29-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta GBCGDNIH2_RS11110 fa73871851f34d84a53819bd72d61b6c 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 29-03-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 GBCGDNIH2_RS11110 fa73871851f34d84a53819bd72d61b6c 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 6.1E-43 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 GBCGDNIH2_RS11110 fa73871851f34d84a53819bd72d61b6c 112 PRINTS PR00340 P-II protein signature 23 41 2.7E-40 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 GBCGDNIH2_RS11110 fa73871851f34d84a53819bd72d61b6c 112 PRINTS PR00340 P-II protein signature 52 75 2.7E-40 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 GBCGDNIH2_RS11110 fa73871851f34d84a53819bd72d61b6c 112 PRINTS PR00340 P-II protein signature 2 17 2.7E-40 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 GBCGDNIH2_RS11110 fa73871851f34d84a53819bd72d61b6c 112 PRINTS PR00340 P-II protein signature 83 103 2.7E-40 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 GBCGDNIH2_RS04400 4829288a20205c5c67d8da07ea539426 230 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 6 223 2.6E-74 T 29-03-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 GBCGDNIH2_RS04400 4829288a20205c5c67d8da07ea539426 230 Gene3D G3DSA:3.40.50.1360 1 140 5.1E-41 T 29-03-2018 GBCGDNIH2_RS04400 4829288a20205c5c67d8da07ea539426 230 SUPERFAMILY SSF75445 131 209 3.4E-19 T 29-03-2018 GBCGDNIH2_RS04400 4829288a20205c5c67d8da07ea539426 230 Gene3D G3DSA:3.30.70.260 141 206 3.5E-23 T 29-03-2018 GBCGDNIH2_RS04400 4829288a20205c5c67d8da07ea539426 230 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 3 226 31.013 T 29-03-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 GBCGDNIH2_RS04400 4829288a20205c5c67d8da07ea539426 230 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 51 221 4.2E-58 T 29-03-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 GBCGDNIH2_RS04400 4829288a20205c5c67d8da07ea539426 230 SUPERFAMILY SSF100950 5 144 1.23E-37 T 29-03-2018 GBCGDNIH2_RS02940 69e3ccaea86bbeaf9c339463aa9f0515 226 TIGRFAM TIGR01351 adk: adenylate kinase 6 217 6.4E-77 T 29-03-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 GBCGDNIH2_RS02940 69e3ccaea86bbeaf9c339463aa9f0515 226 Pfam PF05191 Adenylate kinase, active site lid 131 167 2.6E-12 T 29-03-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 GBCGDNIH2_RS02940 69e3ccaea86bbeaf9c339463aa9f0515 226 SUPERFAMILY SSF52540 7 218 2.46E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS02940 69e3ccaea86bbeaf9c339463aa9f0515 226 PRINTS PR00094 Adenylate kinase signature 85 101 7.1E-36 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 GBCGDNIH2_RS02940 69e3ccaea86bbeaf9c339463aa9f0515 226 PRINTS PR00094 Adenylate kinase signature 165 180 7.1E-36 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 GBCGDNIH2_RS02940 69e3ccaea86bbeaf9c339463aa9f0515 226 PRINTS PR00094 Adenylate kinase signature 8 21 7.1E-36 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 GBCGDNIH2_RS02940 69e3ccaea86bbeaf9c339463aa9f0515 226 PRINTS PR00094 Adenylate kinase signature 36 50 7.1E-36 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 GBCGDNIH2_RS02940 69e3ccaea86bbeaf9c339463aa9f0515 226 PRINTS PR00094 Adenylate kinase signature 182 196 7.1E-36 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 GBCGDNIH2_RS02940 69e3ccaea86bbeaf9c339463aa9f0515 226 Gene3D G3DSA:3.40.50.300 5 222 4.2E-58 T 29-03-2018 GBCGDNIH2_RS02940 69e3ccaea86bbeaf9c339463aa9f0515 226 Hamap MF_00235 Adenylate kinase [adk]. 5 218 48.424 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 GBCGDNIH2_RS02940 69e3ccaea86bbeaf9c339463aa9f0515 226 ProSitePatterns PS00113 Adenylate kinase signature. 85 96 - T 29-03-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 GBCGDNIH2_RS02940 69e3ccaea86bbeaf9c339463aa9f0515 226 Pfam PF00406 Adenylate kinase 9 195 1.8E-56 T 29-03-2018 GBCGDNIH2_RS02180 b7d1efdde1f4cf6ce0a014842ecce1c7 547 Pfam PF12327 FtsZ family, C-terminal domain 227 322 5.9E-39 T 29-03-2018 IPR024757 Cell division protein FtsZ, C-terminal GBCGDNIH2_RS02180 b7d1efdde1f4cf6ce0a014842ecce1c7 547 Gene3D G3DSA:3.30.1330.20 220 329 1.6E-49 T 29-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 GBCGDNIH2_RS02180 b7d1efdde1f4cf6ce0a014842ecce1c7 547 SUPERFAMILY SSF55307 209 324 2.75E-44 T 29-03-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 GBCGDNIH2_RS02180 b7d1efdde1f4cf6ce0a014842ecce1c7 547 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 14 330 3.3E-126 T 29-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 GBCGDNIH2_RS02180 b7d1efdde1f4cf6ce0a014842ecce1c7 547 Gene3D G3DSA:3.40.50.1440 11 219 8.8E-44 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 GBCGDNIH2_RS02180 b7d1efdde1f4cf6ce0a014842ecce1c7 547 ProSitePatterns PS01135 FtsZ protein signature 2. 102 123 - T 29-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 GBCGDNIH2_RS02180 b7d1efdde1f4cf6ce0a014842ecce1c7 547 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 14 342 37.855 T 29-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 GBCGDNIH2_RS02180 b7d1efdde1f4cf6ce0a014842ecce1c7 547 SMART SM00865 212 330 2.4E-60 T 29-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 GBCGDNIH2_RS02180 b7d1efdde1f4cf6ce0a014842ecce1c7 547 PRINTS PR00423 Cell division protein FtsZ signature 217 238 7.1E-51 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 GBCGDNIH2_RS02180 b7d1efdde1f4cf6ce0a014842ecce1c7 547 PRINTS PR00423 Cell division protein FtsZ signature 103 123 7.1E-51 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 GBCGDNIH2_RS02180 b7d1efdde1f4cf6ce0a014842ecce1c7 547 PRINTS PR00423 Cell division protein FtsZ signature 131 152 7.1E-51 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 GBCGDNIH2_RS02180 b7d1efdde1f4cf6ce0a014842ecce1c7 547 PRINTS PR00423 Cell division protein FtsZ signature 194 216 7.1E-51 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 GBCGDNIH2_RS02180 b7d1efdde1f4cf6ce0a014842ecce1c7 547 ProSitePatterns PS01134 FtsZ protein signature 1. 49 83 - T 29-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 GBCGDNIH2_RS02180 b7d1efdde1f4cf6ce0a014842ecce1c7 547 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 18 178 4.1E-41 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 GBCGDNIH2_RS02180 b7d1efdde1f4cf6ce0a014842ecce1c7 547 SMART SM00864 18 210 5.4E-108 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 GBCGDNIH2_RS02180 b7d1efdde1f4cf6ce0a014842ecce1c7 547 SUPERFAMILY SSF52490 17 213 1.7E-68 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 GBCGDNIH2_RS01935 41e8615904197230627e70e3c4ac94a0 112 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 15 30 3.3E-11 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 GBCGDNIH2_RS01935 41e8615904197230627e70e3c4ac94a0 112 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 62 77 3.3E-11 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 GBCGDNIH2_RS01935 41e8615904197230627e70e3c4ac94a0 112 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 47 62 3.3E-11 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 GBCGDNIH2_RS01935 41e8615904197230627e70e3c4ac94a0 112 Gene3D G3DSA:1.10.10.10 1 100 3.8E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS01935 41e8615904197230627e70e3c4ac94a0 112 Pfam PF01022 Bacterial regulatory protein, arsR family 21 65 1.5E-11 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 GBCGDNIH2_RS01935 41e8615904197230627e70e3c4ac94a0 112 SMART SM00418 13 91 3.0E-22 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 GBCGDNIH2_RS01935 41e8615904197230627e70e3c4ac94a0 112 SUPERFAMILY SSF46785 3 92 6.59E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS07805 e97e4795d887a706d01ac4317a9acda2 445 Gene3D G3DSA:2.150.10.10 288 442 1.3E-11 T 29-03-2018 GBCGDNIH2_RS07805 e97e4795d887a706d01ac4317a9acda2 445 Gene3D G3DSA:2.150.10.10 158 287 0.0081 T 29-03-2018 GBCGDNIH2_RS07805 e97e4795d887a706d01ac4317a9acda2 445 PRINTS PR00313 NodO calcium binding signature 251 262 4.3E-6 T 29-03-2018 GBCGDNIH2_RS07805 e97e4795d887a706d01ac4317a9acda2 445 PRINTS PR00313 NodO calcium binding signature 350 358 4.3E-6 T 29-03-2018 GBCGDNIH2_RS07805 e97e4795d887a706d01ac4317a9acda2 445 PRINTS PR00313 NodO calcium binding signature 339 347 4.3E-6 T 29-03-2018 GBCGDNIH2_RS07805 e97e4795d887a706d01ac4317a9acda2 445 PRINTS PR00313 NodO calcium binding signature 368 377 4.3E-6 T 29-03-2018 GBCGDNIH2_RS07805 e97e4795d887a706d01ac4317a9acda2 445 SUPERFAMILY SSF51120 239 431 5.46E-15 T 29-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal GBCGDNIH2_RS01230 10441aec0f0660015551bb6c4bdaba3e 164 Pfam PF09912 Uncharacterized protein conserved in bacteria (DUF2141) 47 155 4.2E-25 T 29-03-2018 IPR018673 Protein of unknown function DUF2141 GBCGDNIH2_RS11830 42e00b0c280b0055cb83f8c55f14b7b9 654 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 416 641 2.2E-38 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GBCGDNIH2_RS11830 42e00b0c280b0055cb83f8c55f14b7b9 654 Pfam PF04545 Sigma-70, region 4 588 641 5.3E-19 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GBCGDNIH2_RS11830 42e00b0c280b0055cb83f8c55f14b7b9 654 SUPERFAMILY SSF88659 493 566 4.36E-21 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GBCGDNIH2_RS11830 42e00b0c280b0055cb83f8c55f14b7b9 654 Pfam PF00140 Sigma-70 factor, region 1.2 117 148 1.8E-13 T 29-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GBCGDNIH2_RS11830 42e00b0c280b0055cb83f8c55f14b7b9 654 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 25 653 43.343 T 29-03-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 GBCGDNIH2_RS11830 42e00b0c280b0055cb83f8c55f14b7b9 654 Pfam PF04546 Sigma-70, non-essential region 159 387 1.3E-48 T 29-03-2018 IPR007631 RNA polymerase sigma factor 70, non-essential domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GBCGDNIH2_RS11830 42e00b0c280b0055cb83f8c55f14b7b9 654 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 613 639 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GBCGDNIH2_RS11830 42e00b0c280b0055cb83f8c55f14b7b9 654 Gene3D G3DSA:1.10.10.10 493 544 1.6E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS11830 42e00b0c280b0055cb83f8c55f14b7b9 654 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 444 457 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GBCGDNIH2_RS11830 42e00b0c280b0055cb83f8c55f14b7b9 654 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 416 652 2.9E-120 T 29-03-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 GBCGDNIH2_RS11830 42e00b0c280b0055cb83f8c55f14b7b9 654 Pfam PF03979 Sigma-70 factor, region 1.1 25 102 5.0E-24 T 29-03-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 GBCGDNIH2_RS11830 42e00b0c280b0055cb83f8c55f14b7b9 654 SUPERFAMILY SSF88659 550 652 2.11E-26 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GBCGDNIH2_RS11830 42e00b0c280b0055cb83f8c55f14b7b9 654 SUPERFAMILY SSF88946 134 487 5.81E-96 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GBCGDNIH2_RS11830 42e00b0c280b0055cb83f8c55f14b7b9 654 Pfam PF04539 Sigma-70 region 3 499 572 1.4E-28 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GBCGDNIH2_RS11830 42e00b0c280b0055cb83f8c55f14b7b9 654 Gene3D G3DSA:1.10.601.10 1 133 5.0E-11 T 29-03-2018 GBCGDNIH2_RS11830 42e00b0c280b0055cb83f8c55f14b7b9 654 Gene3D G3DSA:1.10.601.10 134 489 5.0E-103 T 29-03-2018 GBCGDNIH2_RS11830 42e00b0c280b0055cb83f8c55f14b7b9 654 Pfam PF04542 Sigma-70 region 2 420 489 1.9E-21 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GBCGDNIH2_RS11830 42e00b0c280b0055cb83f8c55f14b7b9 654 PRINTS PR00046 Major sigma-70 factor signature 468 476 3.4E-31 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GBCGDNIH2_RS11830 42e00b0c280b0055cb83f8c55f14b7b9 654 PRINTS PR00046 Major sigma-70 factor signature 628 639 3.4E-31 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GBCGDNIH2_RS11830 42e00b0c280b0055cb83f8c55f14b7b9 654 PRINTS PR00046 Major sigma-70 factor signature 444 457 3.4E-31 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GBCGDNIH2_RS11830 42e00b0c280b0055cb83f8c55f14b7b9 654 PRINTS PR00046 Major sigma-70 factor signature 592 604 3.4E-31 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GBCGDNIH2_RS11830 42e00b0c280b0055cb83f8c55f14b7b9 654 PRINTS PR00046 Major sigma-70 factor signature 613 628 3.4E-31 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GBCGDNIH2_RS11830 42e00b0c280b0055cb83f8c55f14b7b9 654 Gene3D G3DSA:1.10.10.10 582 653 2.6E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS02880 6d404564b8b55b821a7372e528e02419 115 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 1 74 3.0E-31 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS02880 6d404564b8b55b821a7372e528e02419 115 Pfam PF00366 Ribosomal protein S17 8 74 7.9E-33 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS02880 6d404564b8b55b821a7372e528e02419 115 Gene3D G3DSA:2.40.50.140 1 110 7.9E-35 T 29-03-2018 GBCGDNIH2_RS02880 6d404564b8b55b821a7372e528e02419 115 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 3 74 2.4E-35 T 29-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS02880 6d404564b8b55b821a7372e528e02419 115 SUPERFAMILY SSF50249 2 74 9.0E-32 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold GBCGDNIH2_RS02880 6d404564b8b55b821a7372e528e02419 115 PRINTS PR00973 Ribosomal protein S17 family signature 54 64 8.6E-11 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS02880 6d404564b8b55b821a7372e528e02419 115 PRINTS PR00973 Ribosomal protein S17 family signature 22 45 8.6E-11 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS02880 6d404564b8b55b821a7372e528e02419 115 PRINTS PR00973 Ribosomal protein S17 family signature 64 71 8.6E-11 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS02880 6d404564b8b55b821a7372e528e02419 115 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 3 82 23.516 T 29-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS01700 5df6404c4638ab17d29834115fd17880 267 Gene3D G3DSA:2.60.200.30 127 242 2.3E-24 T 29-03-2018 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 GBCGDNIH2_RS01700 5df6404c4638ab17d29834115fd17880 267 Pfam PF01513 ATP-NAD kinase 46 193 6.9E-19 T 29-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 GBCGDNIH2_RS01700 5df6404c4638ab17d29834115fd17880 267 Hamap MF_00361 NAD kinase [nadK]. 16 267 19.327 T 29-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 GBCGDNIH2_RS01700 5df6404c4638ab17d29834115fd17880 267 Gene3D G3DSA:3.40.50.10330 23 126 6.6E-18 T 29-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 GBCGDNIH2_RS01700 5df6404c4638ab17d29834115fd17880 267 SUPERFAMILY SSF111331 38 254 1.57E-53 T 29-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain GBCGDNIH2_RS04445 fde62c453a5cd4872733881aaef653d5 550 Gene3D G3DSA:3.50.50.60 148 273 1.3E-13 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS04445 fde62c453a5cd4872733881aaef653d5 550 Gene3D G3DSA:3.90.190.10 1 140 9.3E-5 T 29-03-2018 IPR029021 Protein-tyrosine phosphatase-like GBCGDNIH2_RS04445 fde62c453a5cd4872733881aaef653d5 550 Gene3D G3DSA:3.50.50.60 394 477 5.1E-6 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS04445 fde62c453a5cd4872733881aaef653d5 550 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 149 270 7.1E-7 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS04445 fde62c453a5cd4872733881aaef653d5 550 Pfam PF04273 Putative phosphatase (DUF442) 3 110 1.7E-27 T 29-03-2018 IPR005939 Beta-lactamase hydrolase-like GO:0016787 GBCGDNIH2_RS04445 fde62c453a5cd4872733881aaef653d5 550 SUPERFAMILY SSF51905 343 468 2.24E-27 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS04445 fde62c453a5cd4872733881aaef653d5 550 SUPERFAMILY SSF51905 147 246 2.24E-27 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS04445 fde62c453a5cd4872733881aaef653d5 550 TIGRFAM TIGR01244 TIGR01244: TIGR01244 family protein 3 136 4.8E-31 T 29-03-2018 IPR005939 Beta-lactamase hydrolase-like GO:0016787 GBCGDNIH2_RS04445 fde62c453a5cd4872733881aaef653d5 550 Gene3D G3DSA:3.50.50.60 274 393 5.7E-32 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS01795 fc01698e50692572581bd35ca45b714d 205 Gene3D G3DSA:1.10.760.10 53 203 3.2E-18 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 GBCGDNIH2_RS01795 fc01698e50692572581bd35ca45b714d 205 PIRSF PIRSF000008 7 205 1.0E-66 T 29-03-2018 IPR009153 Cytochrome cL GO:0005506|GO:0009055|GO:0020037|GO:0042597 GBCGDNIH2_RS01795 fc01698e50692572581bd35ca45b714d 205 TIGRFAM TIGR03872 cytochrome_MoxG: cytochrome c(L), periplasmic 39 168 4.2E-65 T 29-03-2018 IPR009153 Cytochrome cL GO:0005506|GO:0009055|GO:0020037|GO:0042597 GBCGDNIH2_RS01795 fc01698e50692572581bd35ca45b714d 205 SUPERFAMILY SSF46626 61 162 9.89E-24 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 GBCGDNIH2_RS01795 fc01698e50692572581bd35ca45b714d 205 SUPERFAMILY SSF46626 6 26 9.89E-24 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 GBCGDNIH2_RS01795 fc01698e50692572581bd35ca45b714d 205 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 84 156 1.4E-10 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 GBCGDNIH2_RS00430 2b95ab8d007ead4694bf60f9b06b7141 283 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 271 9.3E-25 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GBCGDNIH2_RS00430 2b95ab8d007ead4694bf60f9b06b7141 283 Gene3D G3DSA:1.10.3720.10 31 280 7.4E-32 T 29-03-2018 GBCGDNIH2_RS00430 2b95ab8d007ead4694bf60f9b06b7141 283 SUPERFAMILY SSF161098 91 277 5.23E-39 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GBCGDNIH2_RS00430 2b95ab8d007ead4694bf60f9b06b7141 283 TIGRFAM TIGR03416 ABC_choXWV_perm: choline ABC transporter, permease protein 10 276 3.0E-122 T 29-03-2018 IPR017784 ABC transporter, choline, permease protein GBCGDNIH2_RS09450 e359b9e1d55eb16c5a6c1e51b4e3c16e 169 Gene3D G3DSA:3.10.50.30 86 169 2.5E-21 T 29-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 GBCGDNIH2_RS09450 e359b9e1d55eb16c5a6c1e51b4e3c16e 169 Pfam PF03449 Transcription elongation factor, N-terminal 14 83 8.6E-23 T 29-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 GBCGDNIH2_RS09450 e359b9e1d55eb16c5a6c1e51b4e3c16e 169 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 26 57 - T 29-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 GBCGDNIH2_RS09450 e359b9e1d55eb16c5a6c1e51b4e3c16e 169 Gene3D G3DSA:1.10.287.180 12 85 4.3E-26 T 29-03-2018 GBCGDNIH2_RS09450 e359b9e1d55eb16c5a6c1e51b4e3c16e 169 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 129 145 - T 29-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 GBCGDNIH2_RS09450 e359b9e1d55eb16c5a6c1e51b4e3c16e 169 TIGRFAM TIGR01461 greB: transcription elongation factor GreB 14 166 1.0E-56 T 29-03-2018 IPR006358 Transcription elongation factor GreB GO:0003677|GO:0032784 GBCGDNIH2_RS09450 e359b9e1d55eb16c5a6c1e51b4e3c16e 169 PIRSF PIRSF006092 8 167 6.8E-42 T 29-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 GBCGDNIH2_RS09450 e359b9e1d55eb16c5a6c1e51b4e3c16e 169 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 92 165 8.4E-24 T 29-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 GBCGDNIH2_RS09450 e359b9e1d55eb16c5a6c1e51b4e3c16e 169 SUPERFAMILY SSF54534 91 165 1.96E-18 T 29-03-2018 GBCGDNIH2_RS09450 e359b9e1d55eb16c5a6c1e51b4e3c16e 169 SUPERFAMILY SSF46557 12 86 8.11E-25 T 29-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 GBCGDNIH2_RS09450 e359b9e1d55eb16c5a6c1e51b4e3c16e 169 Hamap MF_00930 Transcription elongation factor GreB [greB]. 10 166 45.783 T 29-03-2018 IPR006358 Transcription elongation factor GreB GO:0003677|GO:0032784 GBCGDNIH2_RS09450 e359b9e1d55eb16c5a6c1e51b4e3c16e 169 Hamap MF_00105 Transcription elongation factor GreA [greA]. 11 164 25.871 T 29-03-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 GBCGDNIH2_RS07395 17a9760886f609f09ee5b28be61d93b9 293 TIGRFAM TIGR00417 speE: spermidine synthase 12 286 8.7E-89 T 29-03-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 GBCGDNIH2_RS07395 17a9760886f609f09ee5b28be61d93b9 293 Gene3D G3DSA:3.40.50.150 64 293 6.6E-37 T 29-03-2018 GBCGDNIH2_RS07395 17a9760886f609f09ee5b28be61d93b9 293 Pfam PF01564 Spermine/spermidine synthase domain 66 247 3.5E-52 T 29-03-2018 GBCGDNIH2_RS07395 17a9760886f609f09ee5b28be61d93b9 293 Gene3D G3DSA:2.30.140.10 10 62 2.2E-15 T 29-03-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 GBCGDNIH2_RS07395 17a9760886f609f09ee5b28be61d93b9 293 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 11 292 36.337 T 29-03-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 GBCGDNIH2_RS07395 17a9760886f609f09ee5b28be61d93b9 293 SUPERFAMILY SSF53335 10 290 8.33E-83 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GBCGDNIH2_RS07395 17a9760886f609f09ee5b28be61d93b9 293 Pfam PF17284 Spermidine synthase tetramerisation domain 12 63 4.1E-12 T 29-03-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 GBCGDNIH2_RS05640 6a95b650194693ccc9394e987de12c5f 491 Gene3D G3DSA:1.10.275.10 27 161 2.7E-59 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal GBCGDNIH2_RS05640 6a95b650194693ccc9394e987de12c5f 491 Gene3D G3DSA:1.10.40.30 439 485 6.1E-19 T 29-03-2018 GBCGDNIH2_RS05640 6a95b650194693ccc9394e987de12c5f 491 Pfam PF00206 Lyase 36 366 8.9E-101 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal GBCGDNIH2_RS05640 6a95b650194693ccc9394e987de12c5f 491 Hamap MF_00743 Fumarate hydratase class II [fumC]. 28 486 81.55 T 29-03-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 GBCGDNIH2_RS05640 6a95b650194693ccc9394e987de12c5f 491 TIGRFAM TIGR00979 fumC_II: fumarate hydratase, class II 29 485 8.5E-206 T 29-03-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 GBCGDNIH2_RS05640 6a95b650194693ccc9394e987de12c5f 491 PRINTS PR00149 Fumarate lyase superfamily signature 341 357 1.1E-32 T 29-03-2018 IPR000362 Fumarate lyase family GBCGDNIH2_RS05640 6a95b650194693ccc9394e987de12c5f 491 PRINTS PR00149 Fumarate lyase superfamily signature 158 176 1.1E-32 T 29-03-2018 IPR000362 Fumarate lyase family GBCGDNIH2_RS05640 6a95b650194693ccc9394e987de12c5f 491 PRINTS PR00149 Fumarate lyase superfamily signature 204 222 1.1E-32 T 29-03-2018 IPR000362 Fumarate lyase family GBCGDNIH2_RS05640 6a95b650194693ccc9394e987de12c5f 491 PRINTS PR00149 Fumarate lyase superfamily signature 295 322 1.1E-32 T 29-03-2018 IPR000362 Fumarate lyase family GBCGDNIH2_RS05640 6a95b650194693ccc9394e987de12c5f 491 Gene3D G3DSA:1.20.200.10 162 438 4.5E-82 T 29-03-2018 GBCGDNIH2_RS05640 6a95b650194693ccc9394e987de12c5f 491 Pfam PF10415 Fumarase C C-terminus 432 485 1.3E-18 T 29-03-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 GBCGDNIH2_RS05640 6a95b650194693ccc9394e987de12c5f 491 ProSitePatterns PS00163 Fumarate lyases signature. 341 350 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 GBCGDNIH2_RS05640 6a95b650194693ccc9394e987de12c5f 491 PRINTS PR00145 Argininosuccinate lyase family signature 341 357 2.9E-6 T 29-03-2018 GBCGDNIH2_RS05640 6a95b650194693ccc9394e987de12c5f 491 PRINTS PR00145 Argininosuccinate lyase family signature 157 179 2.9E-6 T 29-03-2018 GBCGDNIH2_RS05640 6a95b650194693ccc9394e987de12c5f 491 PRINTS PR00145 Argininosuccinate lyase family signature 199 219 2.9E-6 T 29-03-2018 GBCGDNIH2_RS05640 6a95b650194693ccc9394e987de12c5f 491 SUPERFAMILY SSF48557 29 483 1.05E-143 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 GBCGDNIH2_RS00655 38816fc580902ab9906db5a4eaae7824 445 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 31 436 9.7E-134 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 GBCGDNIH2_RS00655 38816fc580902ab9906db5a4eaae7824 445 SUPERFAMILY SSF51419 46 304 1.6E-73 T 29-03-2018 IPR029066 PLP-binding barrel GBCGDNIH2_RS00655 38816fc580902ab9906db5a4eaae7824 445 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 35 436 39.413 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 GBCGDNIH2_RS00655 38816fc580902ab9906db5a4eaae7824 445 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 250 263 - T 29-03-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site GBCGDNIH2_RS00655 38816fc580902ab9906db5a4eaae7824 445 Gene3D G3DSA:3.20.20.10 55 288 7.5E-64 T 29-03-2018 IPR029066 PLP-binding barrel GBCGDNIH2_RS00655 38816fc580902ab9906db5a4eaae7824 445 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 101 393 1.4E-22 T 29-03-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 GBCGDNIH2_RS00655 38816fc580902ab9906db5a4eaae7824 445 PRINTS PR01181 Diaminopimelate decarboxylase signature 97 114 1.1E-26 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 GBCGDNIH2_RS00655 38816fc580902ab9906db5a4eaae7824 445 PRINTS PR01181 Diaminopimelate decarboxylase signature 186 195 1.1E-26 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 GBCGDNIH2_RS00655 38816fc580902ab9906db5a4eaae7824 445 PRINTS PR01181 Diaminopimelate decarboxylase signature 403 425 1.1E-26 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 GBCGDNIH2_RS00655 38816fc580902ab9906db5a4eaae7824 445 PRINTS PR01181 Diaminopimelate decarboxylase signature 320 338 1.1E-26 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 GBCGDNIH2_RS00655 38816fc580902ab9906db5a4eaae7824 445 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 79 97 - T 29-03-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site GBCGDNIH2_RS00655 38816fc580902ab9906db5a4eaae7824 445 SUPERFAMILY SSF50621 276 438 1.53E-49 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 GBCGDNIH2_RS00655 38816fc580902ab9906db5a4eaae7824 445 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 292 311 2.5E-21 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 GBCGDNIH2_RS00655 38816fc580902ab9906db5a4eaae7824 445 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 393 406 2.5E-21 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 GBCGDNIH2_RS00655 38816fc580902ab9906db5a4eaae7824 445 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 79 97 2.5E-21 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 GBCGDNIH2_RS00655 38816fc580902ab9906db5a4eaae7824 445 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 212 225 2.5E-21 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 GBCGDNIH2_RS00655 38816fc580902ab9906db5a4eaae7824 445 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 99 111 2.5E-21 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 GBCGDNIH2_RS00655 38816fc580902ab9906db5a4eaae7824 445 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 56 301 5.2E-54 T 29-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 GBCGDNIH2_RS00655 38816fc580902ab9906db5a4eaae7824 445 Gene3D G3DSA:2.40.37.10 289 441 1.7E-39 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 GBCGDNIH2_RS06660 7b48fb6cbccb7ea438d5929ef0dc80f1 607 Pfam PF13522 Glutamine amidotransferase domain 67 191 1.4E-20 T 29-03-2018 GBCGDNIH2_RS06660 7b48fb6cbccb7ea438d5929ef0dc80f1 607 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 607 38.384 T 29-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 GBCGDNIH2_RS06660 7b48fb6cbccb7ea438d5929ef0dc80f1 607 SUPERFAMILY SSF56235 2 232 1.89E-69 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal GBCGDNIH2_RS06660 7b48fb6cbccb7ea438d5929ef0dc80f1 607 Pfam PF01380 SIS domain 291 414 1.5E-24 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 GBCGDNIH2_RS06660 7b48fb6cbccb7ea438d5929ef0dc80f1 607 Pfam PF01380 SIS domain 460 589 4.0E-22 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 GBCGDNIH2_RS06660 7b48fb6cbccb7ea438d5929ef0dc80f1 607 SUPERFAMILY SSF53697 245 607 3.71E-101 T 29-03-2018 GBCGDNIH2_RS06660 7b48fb6cbccb7ea438d5929ef0dc80f1 607 Gene3D G3DSA:3.40.50.10490 238 453 1.6E-51 T 29-03-2018 GBCGDNIH2_RS06660 7b48fb6cbccb7ea438d5929ef0dc80f1 607 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 607 7.7E-231 T 29-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 GBCGDNIH2_RS06660 7b48fb6cbccb7ea438d5929ef0dc80f1 607 Gene3D G3DSA:3.60.20.10 2 237 9.9E-61 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal GBCGDNIH2_RS06660 7b48fb6cbccb7ea438d5929ef0dc80f1 607 Gene3D G3DSA:3.40.50.10490 454 605 6.7E-47 T 29-03-2018 GBCGDNIH2_RS09680 5f16fe1468d48981a0b5b1989f7155ad 282 Pfam PF03167 Uracil DNA glycosylase superfamily 124 273 1.8E-38 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 GBCGDNIH2_RS09680 5f16fe1468d48981a0b5b1989f7155ad 282 SMART SM00986 121 274 3.2E-36 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 GBCGDNIH2_RS09680 5f16fe1468d48981a0b5b1989f7155ad 282 SMART SM00987 121 274 3.2E-36 T 29-03-2018 GBCGDNIH2_RS09680 5f16fe1468d48981a0b5b1989f7155ad 282 Gene3D G3DSA:3.40.470.10 82 282 5.8E-58 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 GBCGDNIH2_RS09680 5f16fe1468d48981a0b5b1989f7155ad 282 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 108 279 9.4E-55 T 29-03-2018 IPR005273 Uracil-DNA glycosylase family 4 GBCGDNIH2_RS09680 5f16fe1468d48981a0b5b1989f7155ad 282 SUPERFAMILY SSF52141 94 281 1.24E-57 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 GBCGDNIH2_RS04705 b5b691b382e69bf4ca709b1f07f0e05a 100 Hamap MF_00797 UPF0335 protein . 23 100 20.518 T 29-03-2018 IPR018753 Azospirillum phage Cd, Gp10 GBCGDNIH2_RS04705 b5b691b382e69bf4ca709b1f07f0e05a 100 Pfam PF10073 Uncharacterized protein conserved in bacteria (DUF2312) 28 99 4.5E-32 T 29-03-2018 IPR018753 Azospirillum phage Cd, Gp10 GBCGDNIH2_RS11080 090026fa4050aa1f162b27c4447792ca 506 Gene3D G3DSA:1.20.1600.10 23 476 1.8E-88 T 29-03-2018 GBCGDNIH2_RS11080 090026fa4050aa1f162b27c4447792ca 506 SUPERFAMILY SSF56954 8 473 2.35E-100 T 29-03-2018 GBCGDNIH2_RS11080 090026fa4050aa1f162b27c4447792ca 506 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 16 470 2.4E-102 T 29-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 GBCGDNIH2_RS11080 090026fa4050aa1f162b27c4447792ca 506 Pfam PF02321 Outer membrane efflux protein 67 257 4.0E-18 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 GBCGDNIH2_RS11080 090026fa4050aa1f162b27c4447792ca 506 Pfam PF02321 Outer membrane efflux protein 286 468 2.2E-22 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 GBCGDNIH2_RS02960 2866732f526aad56098a8550075daa25 138 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS02960 2866732f526aad56098a8550075daa25 138 SUPERFAMILY SSF64263 1 119 1.44E-50 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS02960 2866732f526aad56098a8550075daa25 138 Gene3D G3DSA:3.90.1030.10 1 117 9.2E-51 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS02960 2866732f526aad56098a8550075daa25 138 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 26.634 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS02960 2866732f526aad56098a8550075daa25 138 TIGRFAM TIGR00059 L17: ribosomal protein bL17 8 117 2.8E-46 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS02960 2866732f526aad56098a8550075daa25 138 Pfam PF01196 Ribosomal protein L17 20 116 3.3E-37 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS09635 25e6c108c43c3077107eda329d5a611d 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 4.7E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS09635 25e6c108c43c3077107eda329d5a611d 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 4.7E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS09635 25e6c108c43c3077107eda329d5a611d 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 4.7E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS09635 25e6c108c43c3077107eda329d5a611d 299 SUPERFAMILY SSF53850 90 295 2.53E-42 T 29-03-2018 GBCGDNIH2_RS09635 25e6c108c43c3077107eda329d5a611d 299 Pfam PF03466 LysR substrate binding domain 89 292 5.9E-40 T 29-03-2018 IPR005119 LysR, substrate-binding GBCGDNIH2_RS09635 25e6c108c43c3077107eda329d5a611d 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 1.9E-21 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS09635 25e6c108c43c3077107eda329d5a611d 299 Gene3D G3DSA:3.40.190.10 175 263 7.3E-27 T 29-03-2018 GBCGDNIH2_RS09635 25e6c108c43c3077107eda329d5a611d 299 Gene3D G3DSA:1.10.10.10 4 85 1.3E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS09635 25e6c108c43c3077107eda329d5a611d 299 Gene3D G3DSA:3.40.190.10 87 174 6.2E-15 T 29-03-2018 GBCGDNIH2_RS09635 25e6c108c43c3077107eda329d5a611d 299 SUPERFAMILY SSF46785 5 107 1.82E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS05645 f0136914536f465004733cc2389b8e46 432 Pfam PF12821 Threonine/Serine exporter, ThrE 288 418 9.1E-10 T 29-03-2018 IPR024528 Threonine/Serine exporter, ThrE GBCGDNIH2_RS05645 f0136914536f465004733cc2389b8e46 432 Pfam PF06738 Putative threonine/serine exporter 26 263 3.9E-30 T 29-03-2018 IPR010619 Putative threonine/serine exporter GBCGDNIH2_RS12105 b40df90dfa637953c7f3c5f5cc6a7059 480 TIGRFAM TIGR02095 glgA: glycogen/starch synthase, ADP-glucose type 1 475 2.4E-164 T 29-03-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 GBCGDNIH2_RS12105 b40df90dfa637953c7f3c5f5cc6a7059 480 Gene3D G3DSA:3.40.50.2000 15 262 1.2E-8 T 29-03-2018 GBCGDNIH2_RS12105 b40df90dfa637953c7f3c5f5cc6a7059 480 SUPERFAMILY SSF53756 5 478 3.01E-114 T 29-03-2018 GBCGDNIH2_RS12105 b40df90dfa637953c7f3c5f5cc6a7059 480 Pfam PF08323 Starch synthase catalytic domain 2 236 5.2E-76 T 29-03-2018 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 GBCGDNIH2_RS12105 b40df90dfa637953c7f3c5f5cc6a7059 480 Hamap MF_00484 Glycogen synthase [glgA]. 1 476 44.59 T 29-03-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 GBCGDNIH2_RS12105 b40df90dfa637953c7f3c5f5cc6a7059 480 Gene3D G3DSA:3.40.50.2000 263 458 1.3E-37 T 29-03-2018 GBCGDNIH2_RS12105 b40df90dfa637953c7f3c5f5cc6a7059 480 Pfam PF00534 Glycosyl transferases group 1 293 438 2.9E-14 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 GBCGDNIH2_RS10185 660ff0f765825af5dd2da2562184a9f6 960 Gene3D G3DSA:3.30.460.10 623 796 8.4E-45 T 29-03-2018 GBCGDNIH2_RS10185 660ff0f765825af5dd2da2562184a9f6 960 Gene3D G3DSA:3.30.460.10 86 266 9.3E-48 T 29-03-2018 GBCGDNIH2_RS10185 660ff0f765825af5dd2da2562184a9f6 960 Hamap MF_00802 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme [glnE]. 4 937 16.463 T 29-03-2018 IPR023057 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme GO:0008882 GBCGDNIH2_RS10185 660ff0f765825af5dd2da2562184a9f6 960 SUPERFAMILY SSF81301 2 268 2.21E-56 T 29-03-2018 GBCGDNIH2_RS10185 660ff0f765825af5dd2da2562184a9f6 960 Pfam PF08335 GlnD PII-uridylyltransferase 279 433 4.4E-44 T 29-03-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 GBCGDNIH2_RS10185 660ff0f765825af5dd2da2562184a9f6 960 Pfam PF08335 GlnD PII-uridylyltransferase 811 946 1.0E-13 T 29-03-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 GBCGDNIH2_RS10185 660ff0f765825af5dd2da2562184a9f6 960 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 545 789 1.9E-53 T 29-03-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 GBCGDNIH2_RS10185 660ff0f765825af5dd2da2562184a9f6 960 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 9 258 4.0E-55 T 29-03-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 GBCGDNIH2_RS10185 660ff0f765825af5dd2da2562184a9f6 960 SUPERFAMILY SSF81593 804 946 2.43E-23 T 29-03-2018 GBCGDNIH2_RS10185 660ff0f765825af5dd2da2562184a9f6 960 Gene3D G3DSA:1.10.4050.10 510 622 8.5E-12 T 29-03-2018 GBCGDNIH2_RS10185 660ff0f765825af5dd2da2562184a9f6 960 Gene3D G3DSA:1.10.4050.10 1 85 1.7E-4 T 29-03-2018 GBCGDNIH2_RS10185 660ff0f765825af5dd2da2562184a9f6 960 SUPERFAMILY SSF81593 269 433 6.36E-38 T 29-03-2018 GBCGDNIH2_RS10185 660ff0f765825af5dd2da2562184a9f6 960 SUPERFAMILY SSF81301 517 793 1.39E-64 T 29-03-2018 GBCGDNIH2_RS10185 660ff0f765825af5dd2da2562184a9f6 960 Gene3D G3DSA:1.20.120.330 798 953 1.0E-29 T 29-03-2018 GBCGDNIH2_RS10185 660ff0f765825af5dd2da2562184a9f6 960 Gene3D G3DSA:1.20.120.330 267 436 6.9E-47 T 29-03-2018 GBCGDNIH2_RS09020 eddcbb31d1134fc21ec57c3d1c362590 50 Pfam PF11752 Protein of unknown function (DUF3309) 2 50 3.5E-24 T 29-03-2018 IPR021738 Protein of unknown function DUF3309 GBCGDNIH2_RS10505 da8796d1cc0fa3fd57648dc99c697b2d 278 SUPERFAMILY SSF51366 2 249 1.22E-85 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 GBCGDNIH2_RS10505 da8796d1cc0fa3fd57648dc99c697b2d 278 Gene3D G3DSA:3.20.20.70 2 277 1.3E-75 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS10505 da8796d1cc0fa3fd57648dc99c697b2d 278 Pfam PF00290 Tryptophan synthase alpha chain 8 253 2.9E-89 T 29-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 GBCGDNIH2_RS10505 da8796d1cc0fa3fd57648dc99c697b2d 278 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 14 271 34.551 T 29-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 GBCGDNIH2_RS10505 da8796d1cc0fa3fd57648dc99c697b2d 278 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 48 61 - T 29-03-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 GBCGDNIH2_RS10505 da8796d1cc0fa3fd57648dc99c697b2d 278 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 8 248 2.5E-73 T 29-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 GBCGDNIH2_RS03685 a6dc9c82f89a95f260096680edbec252 320 SUPERFAMILY SSF51905 3 305 2.66E-56 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS03685 a6dc9c82f89a95f260096680edbec252 320 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 135 155 - T 29-03-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 GBCGDNIH2_RS03685 a6dc9c82f89a95f260096680edbec252 320 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 105 123 5.6E-42 T 29-03-2018 GBCGDNIH2_RS03685 a6dc9c82f89a95f260096680edbec252 320 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 234 250 5.6E-42 T 29-03-2018 GBCGDNIH2_RS03685 a6dc9c82f89a95f260096680edbec252 320 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 5.6E-42 T 29-03-2018 GBCGDNIH2_RS03685 a6dc9c82f89a95f260096680edbec252 320 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 283 5.6E-42 T 29-03-2018 GBCGDNIH2_RS03685 a6dc9c82f89a95f260096680edbec252 320 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 5.6E-42 T 29-03-2018 GBCGDNIH2_RS03685 a6dc9c82f89a95f260096680edbec252 320 Gene3D G3DSA:3.50.50.60 3 146 1.3E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS03685 a6dc9c82f89a95f260096680edbec252 320 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 6 28 4.2E-78 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 GBCGDNIH2_RS03685 a6dc9c82f89a95f260096680edbec252 320 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 195 211 4.2E-78 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 GBCGDNIH2_RS03685 a6dc9c82f89a95f260096680edbec252 320 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 106 114 4.2E-78 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 GBCGDNIH2_RS03685 a6dc9c82f89a95f260096680edbec252 320 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 271 289 4.2E-78 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 GBCGDNIH2_RS03685 a6dc9c82f89a95f260096680edbec252 320 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 60 70 4.2E-78 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 GBCGDNIH2_RS03685 a6dc9c82f89a95f260096680edbec252 320 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 143 167 4.2E-78 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 GBCGDNIH2_RS03685 a6dc9c82f89a95f260096680edbec252 320 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 128 140 4.2E-78 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 GBCGDNIH2_RS03685 a6dc9c82f89a95f260096680edbec252 320 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 39 54 4.2E-78 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 GBCGDNIH2_RS03685 a6dc9c82f89a95f260096680edbec252 320 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 236 257 4.2E-78 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 GBCGDNIH2_RS03685 a6dc9c82f89a95f260096680edbec252 320 Gene3D G3DSA:3.40.50.720 147 257 2.5E-24 T 29-03-2018 GBCGDNIH2_RS03685 a6dc9c82f89a95f260096680edbec252 320 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 6 307 4.8E-122 T 29-03-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 GBCGDNIH2_RS03685 a6dc9c82f89a95f260096680edbec252 320 Gene3D G3DSA:3.50.50.60 258 320 1.7E-9 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS03685 a6dc9c82f89a95f260096680edbec252 320 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 297 8.0E-52 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS05185 07ee034a9088d29971420d3b513ed337 200 Gene3D G3DSA:1.10.287.990 21 89 3.1E-26 T 29-03-2018 GBCGDNIH2_RS05185 07ee034a9088d29971420d3b513ed337 200 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 6.0E-21 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 GBCGDNIH2_RS05185 07ee034a9088d29971420d3b513ed337 200 PRINTS PR01703 Manganese superoxide dismutase signature 28 41 6.0E-21 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 GBCGDNIH2_RS05185 07ee034a9088d29971420d3b513ed337 200 PRINTS PR01703 Manganese superoxide dismutase signature 162 174 6.0E-21 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 GBCGDNIH2_RS05185 07ee034a9088d29971420d3b513ed337 200 PRINTS PR01703 Manganese superoxide dismutase signature 72 85 6.0E-21 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 GBCGDNIH2_RS05185 07ee034a9088d29971420d3b513ed337 200 PRINTS PR01703 Manganese superoxide dismutase signature 124 132 6.0E-21 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 GBCGDNIH2_RS05185 07ee034a9088d29971420d3b513ed337 200 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 89 1.1E-25 T 29-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 GBCGDNIH2_RS05185 07ee034a9088d29971420d3b513ed337 200 PIRSF PIRSF000349 1 200 1.2E-71 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 GBCGDNIH2_RS05185 07ee034a9088d29971420d3b513ed337 200 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 98 197 3.3E-31 T 29-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 GBCGDNIH2_RS05185 07ee034a9088d29971420d3b513ed337 200 SUPERFAMILY SSF54719 91 198 7.86E-36 T 29-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 GBCGDNIH2_RS05185 07ee034a9088d29971420d3b513ed337 200 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 164 171 - T 29-03-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 GBCGDNIH2_RS05185 07ee034a9088d29971420d3b513ed337 200 SUPERFAMILY SSF46609 1 90 5.11E-31 T 29-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 GBCGDNIH2_RS08965 5bf4d02fd26cdd78a9b2ba6d61d7b19f 421 PIRSF PIRSF000151 5 421 4.6E-159 T 29-03-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 GBCGDNIH2_RS08965 5bf4d02fd26cdd78a9b2ba6d61d7b19f 421 SUPERFAMILY SSF53720 12 420 9.69E-108 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 GBCGDNIH2_RS08965 5bf4d02fd26cdd78a9b2ba6d61d7b19f 421 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 12 420 37.928 T 29-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 GBCGDNIH2_RS08965 5bf4d02fd26cdd78a9b2ba6d61d7b19f 421 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 327 349 - T 29-03-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 GBCGDNIH2_RS08965 5bf4d02fd26cdd78a9b2ba6d61d7b19f 421 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 20 410 1.5E-126 T 29-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 GBCGDNIH2_RS08965 5bf4d02fd26cdd78a9b2ba6d61d7b19f 421 Gene3D G3DSA:3.40.605.10 245 421 3.9E-33 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 GBCGDNIH2_RS08965 5bf4d02fd26cdd78a9b2ba6d61d7b19f 421 Gene3D G3DSA:3.40.605.10 2 244 7.1E-40 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 GBCGDNIH2_RS08965 5bf4d02fd26cdd78a9b2ba6d61d7b19f 421 Pfam PF00171 Aldehyde dehydrogenase family 5 288 1.4E-16 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 GBCGDNIH2_RS06005 5d9909ff27a54e46f9e49a99f15a5ce6 348 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 85 100 - T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 GBCGDNIH2_RS06005 5d9909ff27a54e46f9e49a99f15a5ce6 348 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 85 342 2.3E-89 T 29-03-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 GBCGDNIH2_RS06005 5d9909ff27a54e46f9e49a99f15a5ce6 348 SUPERFAMILY SSF51717 82 342 8.63E-90 T 29-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 GBCGDNIH2_RS06005 5d9909ff27a54e46f9e49a99f15a5ce6 348 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 119 132 - T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 GBCGDNIH2_RS06005 5d9909ff27a54e46f9e49a99f15a5ce6 348 Gene3D G3DSA:3.20.20.20 70 347 4.5E-100 T 29-03-2018 GBCGDNIH2_RS06005 5d9909ff27a54e46f9e49a99f15a5ce6 348 Pfam PF00809 Pterin binding enzyme 86 330 2.5E-77 T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 GBCGDNIH2_RS02095 2e50db56e077903df3ac7a82ea5c3eef 238 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GBCGDNIH2_RS02095 2e50db56e077903df3ac7a82ea5c3eef 238 Pfam PF00005 ABC transporter 40 168 3.2E-24 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GBCGDNIH2_RS02095 2e50db56e077903df3ac7a82ea5c3eef 238 SUPERFAMILY SSF52540 3 199 3.59E-36 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS02095 2e50db56e077903df3ac7a82ea5c3eef 238 SMART SM00382 36 230 1.7E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS02095 2e50db56e077903df3ac7a82ea5c3eef 238 TIGRFAM TIGR01189 ccmA: heme ABC exporter, ATP-binding protein CcmA 2 208 6.5E-58 T 29-03-2018 IPR005895 ABC transporter, haem export, CcmA GO:0005215|GO:0017004|GO:0030288 GBCGDNIH2_RS02095 2e50db56e077903df3ac7a82ea5c3eef 238 Gene3D G3DSA:3.40.50.300 1 204 1.8E-38 T 29-03-2018 GBCGDNIH2_RS07070 475be103f56e7ad83aad0e12414a3fbe 605 SUPERFAMILY SSF48208 197 595 5.95E-112 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 GBCGDNIH2_RS07070 475be103f56e7ad83aad0e12414a3fbe 605 Gene3D G3DSA:1.50.10.10 197 550 7.0E-101 T 29-03-2018 GBCGDNIH2_RS07070 475be103f56e7ad83aad0e12414a3fbe 605 Pfam PF00723 Glycosyl hydrolases family 15 226 589 7.9E-69 T 29-03-2018 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: R-HSA-70221 GBCGDNIH2_RS12190 cc0bfc0912ff8d87c91d3586cad3684e 720 Gene3D G3DSA:2.40.50.140 629 696 7.6E-22 T 29-03-2018 GBCGDNIH2_RS12190 cc0bfc0912ff8d87c91d3586cad3684e 720 Gene3D G3DSA:3.30.230.70 13 226 4.6E-50 T 29-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 GBCGDNIH2_RS12190 cc0bfc0912ff8d87c91d3586cad3684e 720 Pfam PF00575 S1 RNA binding domain 618 690 9.7E-16 T 29-03-2018 IPR003029 S1 domain GO:0003676 GBCGDNIH2_RS12190 cc0bfc0912ff8d87c91d3586cad3684e 720 SUPERFAMILY SSF54211 291 488 3.64E-50 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold GBCGDNIH2_RS12190 cc0bfc0912ff8d87c91d3586cad3684e 720 Pfam PF03725 3' exoribonuclease family, domain 2 147 211 3.2E-15 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 GBCGDNIH2_RS12190 cc0bfc0912ff8d87c91d3586cad3684e 720 SUPERFAMILY SSF54211 2 144 5.06E-53 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold GBCGDNIH2_RS12190 cc0bfc0912ff8d87c91d3586cad3684e 720 Gene3D G3DSA:3.30.1370.10 555 628 4.6E-15 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 GBCGDNIH2_RS12190 cc0bfc0912ff8d87c91d3586cad3684e 720 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 3 693 30.869 T 29-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 GBCGDNIH2_RS12190 cc0bfc0912ff8d87c91d3586cad3684e 720 Pfam PF00013 KH domain 556 613 9.1E-11 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 GBCGDNIH2_RS12190 cc0bfc0912ff8d87c91d3586cad3684e 720 SMART SM00322 552 617 4.0E-11 T 29-03-2018 IPR004087 K Homology domain GO:0003676 GBCGDNIH2_RS12190 cc0bfc0912ff8d87c91d3586cad3684e 720 Gene3D G3DSA:3.30.230.70 318 544 7.2E-58 T 29-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 GBCGDNIH2_RS12190 cc0bfc0912ff8d87c91d3586cad3684e 720 SUPERFAMILY SSF55666 450 544 2.38E-26 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 GBCGDNIH2_RS12190 cc0bfc0912ff8d87c91d3586cad3684e 720 SMART SM00316 620 690 2.8E-21 T 29-03-2018 IPR022967 RNA-binding domain, S1 GBCGDNIH2_RS12190 cc0bfc0912ff8d87c91d3586cad3684e 720 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 11 690 0.0 T 29-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 GBCGDNIH2_RS12190 cc0bfc0912ff8d87c91d3586cad3684e 720 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 243 320 5.7E-12 T 29-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 GBCGDNIH2_RS12190 cc0bfc0912ff8d87c91d3586cad3684e 720 SUPERFAMILY SSF55666 138 230 5.37E-27 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 GBCGDNIH2_RS12190 cc0bfc0912ff8d87c91d3586cad3684e 720 Gene3D G3DSA:1.10.10.400 240 317 8.5E-14 T 29-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 GBCGDNIH2_RS12190 cc0bfc0912ff8d87c91d3586cad3684e 720 PIRSF PIRSF005499 1 714 1.4E-292 T 29-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 GBCGDNIH2_RS12190 cc0bfc0912ff8d87c91d3586cad3684e 720 SUPERFAMILY SSF54791 555 640 1.21E-21 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 GBCGDNIH2_RS12190 cc0bfc0912ff8d87c91d3586cad3684e 720 Pfam PF01138 3' exoribonuclease family, domain 1 14 144 1.6E-23 T 29-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 GBCGDNIH2_RS12190 cc0bfc0912ff8d87c91d3586cad3684e 720 Pfam PF01138 3' exoribonuclease family, domain 1 324 456 5.1E-22 T 29-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 GBCGDNIH2_RS12190 cc0bfc0912ff8d87c91d3586cad3684e 720 SUPERFAMILY SSF50249 620 702 6.79E-20 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold GBCGDNIH2_RS06560 7c406a7d386502cdde36dc1f3733632f 183 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 13 166 4.0E-57 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 GBCGDNIH2_RS06560 7c406a7d386502cdde36dc1f3733632f 183 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 11 172 34.579 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 GBCGDNIH2_RS06560 7c406a7d386502cdde36dc1f3733632f 183 SUPERFAMILY SSF52374 11 165 4.02E-40 T 29-03-2018 GBCGDNIH2_RS06560 7c406a7d386502cdde36dc1f3733632f 183 Gene3D G3DSA:3.40.50.620 1 170 8.1E-33 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GBCGDNIH2_RS06560 7c406a7d386502cdde36dc1f3733632f 183 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 13 67 2.3E-18 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 GBCGDNIH2_RS06560 7c406a7d386502cdde36dc1f3733632f 183 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 99 115 3.3E-36 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 GBCGDNIH2_RS06560 7c406a7d386502cdde36dc1f3733632f 183 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 126 148 3.3E-36 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 GBCGDNIH2_RS06560 7c406a7d386502cdde36dc1f3733632f 183 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 29 50 3.3E-36 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 GBCGDNIH2_RS06560 7c406a7d386502cdde36dc1f3733632f 183 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 11 29 3.3E-36 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 GBCGDNIH2_RS06560 7c406a7d386502cdde36dc1f3733632f 183 Pfam PF01467 Cytidylyltransferase-like 14 146 1.2E-18 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 GBCGDNIH2_RS08120 4748a0c4f814df4d8e94e3893e6c5534 488 SMART SM00987 309 469 1.9E-34 T 29-03-2018 GBCGDNIH2_RS08120 4748a0c4f814df4d8e94e3893e6c5534 488 Gene3D G3DSA:3.40.470.10 271 476 1.9E-49 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 GBCGDNIH2_RS08120 4748a0c4f814df4d8e94e3893e6c5534 488 Pfam PF03167 Uracil DNA glycosylase superfamily 309 462 4.1E-29 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 GBCGDNIH2_RS08120 4748a0c4f814df4d8e94e3893e6c5534 488 SUPERFAMILY SSF52141 285 475 1.24E-49 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 GBCGDNIH2_RS08120 4748a0c4f814df4d8e94e3893e6c5534 488 Pfam PF13566 Domain of unknown function (DUF4130 76 233 1.6E-36 T 29-03-2018 IPR025404 Domain of unknown function DUF4130 GBCGDNIH2_RS08120 4748a0c4f814df4d8e94e3893e6c5534 488 TIGRFAM TIGR03915 SAM_7_link_chp: probable DNA metabolism protein 13 234 7.3E-51 T 29-03-2018 IPR023875 DNA metabolism protein, putative GBCGDNIH2_RS08120 4748a0c4f814df4d8e94e3893e6c5534 488 SMART SM00986 309 469 1.9E-34 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 GBCGDNIH2_RS08120 4748a0c4f814df4d8e94e3893e6c5534 488 TIGRFAM TIGR03914 UDG_fam_dom: uracil-DNA glycosylase family domain 236 470 2.0E-84 T 29-03-2018 IPR005273 Uracil-DNA glycosylase family 4 GBCGDNIH2_RS11415 4b25d22516fdeef9400785db1947ce85 341 SUPERFAMILY SSF55821 15 210 3.05E-54 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain GBCGDNIH2_RS11415 4b25d22516fdeef9400785db1947ce85 341 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 18 208 2.5E-47 T 29-03-2018 IPR006070 YrdC-like domain GO:0003725 GBCGDNIH2_RS11415 4b25d22516fdeef9400785db1947ce85 341 Pfam PF01300 Telomere recombination 21 197 9.9E-47 T 29-03-2018 IPR006070 YrdC-like domain GO:0003725 GBCGDNIH2_RS11415 4b25d22516fdeef9400785db1947ce85 341 PIRSF PIRSF004930 9 335 7.6E-92 T 29-03-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 GBCGDNIH2_RS11415 4b25d22516fdeef9400785db1947ce85 341 Gene3D G3DSA:3.90.870.10 8 213 3.7E-66 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain GBCGDNIH2_RS11415 4b25d22516fdeef9400785db1947ce85 341 Pfam PF03481 Putative GTP-binding controlling metal-binding 199 329 4.9E-17 T 29-03-2018 IPR005145 Putative GTP-binding controlling metal-binding domain GBCGDNIH2_RS03865 aa23ba92405c09a61fba837b2dd36e0c 734 SUPERFAMILY SSF81296 21 117 1.61E-13 T 29-03-2018 IPR014756 Immunoglobulin E-set GBCGDNIH2_RS03865 aa23ba92405c09a61fba837b2dd36e0c 734 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 111 731 1.1E-274 T 29-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 GBCGDNIH2_RS03865 aa23ba92405c09a61fba837b2dd36e0c 734 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 103 733 44.261 T 29-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 GBCGDNIH2_RS03865 aa23ba92405c09a61fba837b2dd36e0c 734 SUPERFAMILY SSF51445 181 623 3.84E-114 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily GBCGDNIH2_RS03865 aa23ba92405c09a61fba837b2dd36e0c 734 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 634 732 5.6E-21 T 29-03-2018 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 GBCGDNIH2_RS03865 aa23ba92405c09a61fba837b2dd36e0c 734 Gene3D G3DSA:2.60.40.1180 629 733 1.7E-31 T 29-03-2018 GBCGDNIH2_RS03865 aa23ba92405c09a61fba837b2dd36e0c 734 Pfam PF00128 Alpha amylase, catalytic domain 271 355 6.1E-7 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 GBCGDNIH2_RS03865 aa23ba92405c09a61fba837b2dd36e0c 734 SUPERFAMILY SSF81296 117 229 2.03E-21 T 29-03-2018 IPR014756 Immunoglobulin E-set GBCGDNIH2_RS03865 aa23ba92405c09a61fba837b2dd36e0c 734 PIRSF PIRSF000463 11 734 8.3E-281 T 29-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 GBCGDNIH2_RS03865 aa23ba92405c09a61fba837b2dd36e0c 734 Gene3D G3DSA:3.20.20.80 252 618 5.9E-75 T 29-03-2018 GBCGDNIH2_RS03865 aa23ba92405c09a61fba837b2dd36e0c 734 Gene3D G3DSA:2.60.40.10 116 251 3.5E-30 T 29-03-2018 IPR013783 Immunoglobulin-like fold GBCGDNIH2_RS03865 aa23ba92405c09a61fba837b2dd36e0c 734 Gene3D G3DSA:2.60.40.10 8 108 8.9E-9 T 29-03-2018 IPR013783 Immunoglobulin-like fold GBCGDNIH2_RS03865 aa23ba92405c09a61fba837b2dd36e0c 734 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 127 215 2.9E-21 T 29-03-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077 GBCGDNIH2_RS03865 aa23ba92405c09a61fba837b2dd36e0c 734 SUPERFAMILY SSF51011 630 733 2.16E-34 T 29-03-2018 GBCGDNIH2_RS03865 aa23ba92405c09a61fba837b2dd36e0c 734 SMART SM00642 259 612 5.2E-6 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 GBCGDNIH2_RS06600 f8d6250feb528bc033eee0cc6c901fee 361 Gene3D G3DSA:3.30.565.10 190 360 4.3E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS06600 f8d6250feb528bc033eee0cc6c901fee 361 SMART SM00387 231 354 1.0E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS06600 f8d6250feb528bc033eee0cc6c901fee 361 SUPERFAMILY SSF47384 121 185 2.55E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GBCGDNIH2_RS06600 f8d6250feb528bc033eee0cc6c901fee 361 PRINTS PR00344 Bacterial sensor protein C-terminal signature 286 300 1.2E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS06600 f8d6250feb528bc033eee0cc6c901fee 361 PRINTS PR00344 Bacterial sensor protein C-terminal signature 338 351 1.2E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS06600 f8d6250feb528bc033eee0cc6c901fee 361 PRINTS PR00344 Bacterial sensor protein C-terminal signature 304 314 1.2E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS06600 f8d6250feb528bc033eee0cc6c901fee 361 PRINTS PR00344 Bacterial sensor protein C-terminal signature 315 333 1.2E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS06600 f8d6250feb528bc033eee0cc6c901fee 361 Gene3D G3DSA:1.10.287.130 119 185 2.7E-11 T 29-03-2018 GBCGDNIH2_RS06600 f8d6250feb528bc033eee0cc6c901fee 361 SMART SM00388 127 191 7.8E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GBCGDNIH2_RS06600 f8d6250feb528bc033eee0cc6c901fee 361 SUPERFAMILY SSF55874 187 356 1.44E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS06600 f8d6250feb528bc033eee0cc6c901fee 361 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 232 351 6.2E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS06600 f8d6250feb528bc033eee0cc6c901fee 361 SMART SM00091 2 69 8.4E-6 T 29-03-2018 IPR000014 PAS domain GBCGDNIH2_RS06600 f8d6250feb528bc033eee0cc6c901fee 361 Gene3D G3DSA:3.30.450.20 9 118 1.9E-9 T 29-03-2018 GBCGDNIH2_RS06600 f8d6250feb528bc033eee0cc6c901fee 361 SUPERFAMILY SSF55785 11 56 3.59E-6 T 29-03-2018 IPR000014 PAS domain GBCGDNIH2_RS06600 f8d6250feb528bc033eee0cc6c901fee 361 Pfam PF00512 His Kinase A (phospho-acceptor) domain 131 184 2.4E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GBCGDNIH2_RS06600 f8d6250feb528bc033eee0cc6c901fee 361 Pfam PF00989 PAS fold 12 108 5.1E-7 T 29-03-2018 IPR013767 PAS fold GO:0006355 GBCGDNIH2_RS00940 5cda02812d03b0840878d8b5176adecf 297 SUPERFAMILY SSF103481 190 288 8.11E-11 T 29-03-2018 GBCGDNIH2_RS00940 5cda02812d03b0840878d8b5176adecf 297 SUPERFAMILY SSF103481 60 136 9.94E-10 T 29-03-2018 GBCGDNIH2_RS00940 5cda02812d03b0840878d8b5176adecf 297 Pfam PF00892 EamA-like transporter family 160 287 1.2E-10 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 GBCGDNIH2_RS00940 5cda02812d03b0840878d8b5176adecf 297 Pfam PF00892 EamA-like transporter family 2 135 2.7E-11 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 GBCGDNIH2_RS10980 f8978ca70f63ff9202c043713c857291 435 Gene3D G3DSA:3.10.20.70 2 94 1.8E-14 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 GBCGDNIH2_RS10980 f8978ca70f63ff9202c043713c857291 435 SMART SM01230 97 349 3.6E-110 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 GBCGDNIH2_RS10980 f8978ca70f63ff9202c043713c857291 435 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 225 240 - T 29-03-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 GBCGDNIH2_RS10980 f8978ca70f63ff9202c043713c857291 435 Gene3D G3DSA:3.30.590.10 96 435 1.4E-106 T 29-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 GBCGDNIH2_RS10980 f8978ca70f63ff9202c043713c857291 435 SUPERFAMILY SSF55931 98 434 2.45E-107 T 29-03-2018 GBCGDNIH2_RS10980 f8978ca70f63ff9202c043713c857291 435 Pfam PF00120 Glutamine synthetase, catalytic domain 99 431 1.2E-104 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 GBCGDNIH2_RS10980 f8978ca70f63ff9202c043713c857291 435 TIGRFAM TIGR03105 gln_synth_III: glutamine synthetase, type III 6 434 6.9E-193 T 29-03-2018 IPR017536 Glutamine synthetase, type III GBCGDNIH2_RS10980 f8978ca70f63ff9202c043713c857291 435 SUPERFAMILY SSF54368 7 90 1.44E-17 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 GBCGDNIH2_RS00610 86998e2c5a894398178b8172648ca8e0 654 Gene3D G3DSA:3.10.20.310 64 166 0.35 T 29-03-2018 GBCGDNIH2_RS00610 86998e2c5a894398178b8172648ca8e0 654 Gene3D G3DSA:3.10.20.310 179 248 2.4E-6 T 29-03-2018 GBCGDNIH2_RS00610 86998e2c5a894398178b8172648ca8e0 654 Gene3D G3DSA:2.40.160.50 292 654 2.5E-62 T 29-03-2018 GBCGDNIH2_RS00610 86998e2c5a894398178b8172648ca8e0 654 Pfam PF01103 Surface antigen 350 654 5.4E-38 T 29-03-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 GBCGDNIH2_RS00610 86998e2c5a894398178b8172648ca8e0 654 Gene3D G3DSA:3.10.20.310 250 291 0.029 T 29-03-2018 GBCGDNIH2_RS00610 86998e2c5a894398178b8172648ca8e0 654 Pfam PF07244 Surface antigen variable number repeat 252 322 5.1E-7 T 29-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 GBCGDNIH2_RS00610 86998e2c5a894398178b8172648ca8e0 654 Pfam PF07244 Surface antigen variable number repeat 186 246 2.0E-4 T 29-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 GBCGDNIH2_RS08055 e97e6c532edba164463f87544c82a595 110 SUPERFAMILY SSF143100 1 75 2.17E-5 T 29-03-2018 IPR035069 TTHA1013/TTHA0281-like GBCGDNIH2_RS08055 e97e6c532edba164463f87544c82a595 110 SUPERFAMILY SSF47598 71 109 1.19E-8 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 GBCGDNIH2_RS08055 e97e6c532edba164463f87544c82a595 110 Gene3D G3DSA:1.10.1220.10 54 110 2.4E-17 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 GBCGDNIH2_RS08055 e97e6c532edba164463f87544c82a595 110 Pfam PF05534 HicB family 54 104 2.3E-19 T 29-03-2018 IPR008651 Uncharacterised protein family HicB GBCGDNIH2_RS12035 695f674b3054e83685e403253da54aee 312 Gene3D G3DSA:3.40.50.150 53 312 1.1E-55 T 29-03-2018 GBCGDNIH2_RS12035 695f674b3054e83685e403253da54aee 312 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 110 130 7.1E-26 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 GBCGDNIH2_RS12035 695f674b3054e83685e403253da54aee 312 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 264 282 7.1E-26 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 GBCGDNIH2_RS12035 695f674b3054e83685e403253da54aee 312 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 287 307 7.1E-26 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 GBCGDNIH2_RS12035 695f674b3054e83685e403253da54aee 312 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 245 262 7.1E-26 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 GBCGDNIH2_RS12035 695f674b3054e83685e403253da54aee 312 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 75 89 7.1E-26 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 GBCGDNIH2_RS12035 695f674b3054e83685e403253da54aee 312 Pfam PF01555 DNA methylase 76 303 6.9E-42 T 29-03-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 GBCGDNIH2_RS12035 695f674b3054e83685e403253da54aee 312 SUPERFAMILY SSF53335 52 307 2.16E-57 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GBCGDNIH2_RS12035 695f674b3054e83685e403253da54aee 312 ProSitePatterns PS00093 N-4 cytosine-specific DNA methylases signature. 80 85 - T 29-03-2018 IPR017985 DNA methylase, N-4 cytosine-specific, conserved site GO:0003677|GO:0015667|GO:0090124 KEGG: 00860+2.1.1.11|MetaCyc: PWY-5531|MetaCyc: PWY-7159 GBCGDNIH2_RS06945 3d61732018d7d3640c4d2917d4275c57 685 Pfam PF00384 Molybdopterin oxidoreductase 272 593 3.5E-64 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS06945 3d61732018d7d3640c4d2917d4275c57 685 Gene3D G3DSA:3.10.20.30 1 164 1.5E-16 T 29-03-2018 IPR012675 Beta-grasp domain GBCGDNIH2_RS06945 3d61732018d7d3640c4d2917d4275c57 685 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 1 77 6.4E-19 T 29-03-2018 GBCGDNIH2_RS06945 3d61732018d7d3640c4d2917d4275c57 685 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 99 111 - T 29-03-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS06945 3d61732018d7d3640c4d2917d4275c57 685 SUPERFAMILY SSF53706 214 621 1.45E-92 T 29-03-2018 GBCGDNIH2_RS06945 3d61732018d7d3640c4d2917d4275c57 685 SUPERFAMILY SSF54292 1 75 2.42E-21 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 GBCGDNIH2_RS06945 3d61732018d7d3640c4d2917d4275c57 685 TIGRFAM TIGR01973 NuoG: NADH dehydrogenase (quinone), G subunit 4 590 6.9E-221 T 29-03-2018 IPR010228 NADH:ubiquinone oxidoreductase, subunit G GO:0016651|GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS06945 3d61732018d7d3640c4d2917d4275c57 685 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 84 123 1.7E-17 T 29-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS06945 3d61732018d7d3640c4d2917d4275c57 685 Gene3D G3DSA:3.40.50.740 421 602 4.2E-29 T 29-03-2018 GBCGDNIH2_RS06945 3d61732018d7d3640c4d2917d4275c57 685 Gene3D G3DSA:3.40.50.740 262 420 1.3E-17 T 29-03-2018 GBCGDNIH2_RS06945 3d61732018d7d3640c4d2917d4275c57 685 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 31 48 - T 29-03-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS06945 3d61732018d7d3640c4d2917d4275c57 685 ProSitePatterns PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. 146 156 - T 29-03-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS06945 3d61732018d7d3640c4d2917d4275c57 685 SUPERFAMILY SSF54862 76 212 1.42E-37 T 29-03-2018 GBCGDNIH2_RS06945 3d61732018d7d3640c4d2917d4275c57 685 Pfam PF09326 NADH-ubiquinone oxidoreductase subunit G, C-terminal 633 669 8.0E-12 T 29-03-2018 IPR015405 NADH-quinone oxidoreductase, chain G, C-terminal GO:0016651|GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS06945 3d61732018d7d3640c4d2917d4275c57 685 SMART SM00929 84 124 2.8E-21 T 29-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS11105 de9379329f5b706413b358faa38aa84d 470 ProSitePatterns PS01219 Ammonium transporters signature. 224 249 - T 29-03-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 GBCGDNIH2_RS11105 de9379329f5b706413b358faa38aa84d 470 SUPERFAMILY SSF111352 60 451 4.71E-130 T 29-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 GBCGDNIH2_RS11105 de9379329f5b706413b358faa38aa84d 470 TIGRFAM TIGR00836 amt: ammonium transporter 64 467 5.9E-137 T 29-03-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 GBCGDNIH2_RS11105 de9379329f5b706413b358faa38aa84d 470 Gene3D G3DSA:1.10.3430.10 56 451 1.7E-134 T 29-03-2018 GBCGDNIH2_RS11105 de9379329f5b706413b358faa38aa84d 470 Pfam PF00909 Ammonium Transporter Family 66 467 1.4E-123 T 29-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 GBCGDNIH2_RS05720 b6f5474d46e3620251e6c9b5e55ee19d 313 Gene3D G3DSA:3.90.180.10 1 144 8.5E-28 T 29-03-2018 GBCGDNIH2_RS05720 b6f5474d46e3620251e6c9b5e55ee19d 313 Gene3D G3DSA:3.40.50.720 145 262 1.1E-13 T 29-03-2018 GBCGDNIH2_RS05720 b6f5474d46e3620251e6c9b5e55ee19d 313 SMART SM00829 10 310 1.4E-5 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 GBCGDNIH2_RS05720 b6f5474d46e3620251e6c9b5e55ee19d 313 SUPERFAMILY SSF50129 1 137 6.45E-21 T 29-03-2018 IPR011032 GroES-like GBCGDNIH2_RS05720 b6f5474d46e3620251e6c9b5e55ee19d 313 SUPERFAMILY SSF51735 104 263 5.59E-24 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS06855 cf64e66a8d46a810d33b4cd650a91c9c 304 Hamap MF_00050 Elongation factor Ts [tsf]. 1 301 76.816 T 29-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 GBCGDNIH2_RS06855 cf64e66a8d46a810d33b4cd650a91c9c 304 Gene3D G3DSA:1.10.8.10 1 56 1.1E-26 T 29-03-2018 GBCGDNIH2_RS06855 cf64e66a8d46a810d33b4cd650a91c9c 304 Gene3D G3DSA:3.30.479.20 58 161 3.0E-21 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 GBCGDNIH2_RS06855 cf64e66a8d46a810d33b4cd650a91c9c 304 ProSitePatterns PS01127 Elongation factor Ts signature 2. 75 85 - T 29-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 GBCGDNIH2_RS06855 cf64e66a8d46a810d33b4cd650a91c9c 304 ProSitePatterns PS01126 Elongation factor Ts signature 1. 12 27 - T 29-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 GBCGDNIH2_RS06855 cf64e66a8d46a810d33b4cd650a91c9c 304 Gene3D G3DSA:3.30.479.20 162 300 5.0E-44 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 GBCGDNIH2_RS06855 cf64e66a8d46a810d33b4cd650a91c9c 304 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 300 4.5E-92 T 29-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 GBCGDNIH2_RS06855 cf64e66a8d46a810d33b4cd650a91c9c 304 SUPERFAMILY SSF54713 150 301 1.57E-43 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 GBCGDNIH2_RS06855 cf64e66a8d46a810d33b4cd650a91c9c 304 SUPERFAMILY SSF46934 4 55 1.41E-19 T 29-03-2018 IPR009060 UBA-like GO:0005515 GBCGDNIH2_RS06855 cf64e66a8d46a810d33b4cd650a91c9c 304 Pfam PF00889 Elongation factor TS 71 283 3.5E-66 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 GBCGDNIH2_RS06855 cf64e66a8d46a810d33b4cd650a91c9c 304 SUPERFAMILY SSF54713 56 145 3.92E-19 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 GBCGDNIH2_RS04405 796aa06eeb32c3315f4bc13e724261b2 168 TIGRFAM TIGR01313 therm_gnt_kin: carbohydrate kinase, thermoresistant glucokinase family 9 165 3.4E-48 T 29-03-2018 IPR006001 Carbohydrate kinase, thermoresistant glucokinase GO:0005975|GO:0016301 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530 GBCGDNIH2_RS04405 796aa06eeb32c3315f4bc13e724261b2 168 Gene3D G3DSA:3.40.50.300 5 168 7.8E-35 T 29-03-2018 GBCGDNIH2_RS04405 796aa06eeb32c3315f4bc13e724261b2 168 Pfam PF01202 Shikimate kinase 15 167 1.6E-13 T 29-03-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 GBCGDNIH2_RS04405 796aa06eeb32c3315f4bc13e724261b2 168 SUPERFAMILY SSF52540 5 167 1.12E-28 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS04105 d3fc012b3a3ff90cb2dfed3b2a4e8aa0 492 PIRSF PIRSF000110 1 489 8.3E-168 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 GBCGDNIH2_RS04105 d3fc012b3a3ff90cb2dfed3b2a4e8aa0 492 Gene3D G3DSA:3.40.50.720 7 189 2.6E-60 T 29-03-2018 GBCGDNIH2_RS04105 d3fc012b3a3ff90cb2dfed3b2a4e8aa0 492 Gene3D G3DSA:3.30.360.10 190 488 1.3E-125 T 29-03-2018 GBCGDNIH2_RS04105 d3fc012b3a3ff90cb2dfed3b2a4e8aa0 492 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 238 254 6.6E-49 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 GBCGDNIH2_RS04105 d3fc012b3a3ff90cb2dfed3b2a4e8aa0 492 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 168 196 6.6E-49 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 GBCGDNIH2_RS04105 d3fc012b3a3ff90cb2dfed3b2a4e8aa0 492 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 220 237 6.6E-49 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 GBCGDNIH2_RS04105 d3fc012b3a3ff90cb2dfed3b2a4e8aa0 492 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 327 353 6.6E-49 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 GBCGDNIH2_RS04105 d3fc012b3a3ff90cb2dfed3b2a4e8aa0 492 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 144 157 6.6E-49 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 GBCGDNIH2_RS04105 d3fc012b3a3ff90cb2dfed3b2a4e8aa0 492 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 178 184 - T 29-03-2018 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 GBCGDNIH2_RS04105 d3fc012b3a3ff90cb2dfed3b2a4e8aa0 492 SUPERFAMILY SSF51735 4 191 7.87E-56 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS04105 d3fc012b3a3ff90cb2dfed3b2a4e8aa0 492 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 13 188 1.7E-57 T 29-03-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 GBCGDNIH2_RS04105 d3fc012b3a3ff90cb2dfed3b2a4e8aa0 492 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 13 487 6.7E-176 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 GBCGDNIH2_RS04105 d3fc012b3a3ff90cb2dfed3b2a4e8aa0 492 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 9 487 84.518 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 GBCGDNIH2_RS04105 d3fc012b3a3ff90cb2dfed3b2a4e8aa0 492 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 191 486 1.6E-112 T 29-03-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 GBCGDNIH2_RS04105 d3fc012b3a3ff90cb2dfed3b2a4e8aa0 492 SUPERFAMILY SSF55347 183 486 3.27E-112 T 29-03-2018 GBCGDNIH2_RS11800 b21b7ae6952e1dae9ab95f20fe94baf7 313 SUPERFAMILY SSF51735 5 276 6.32E-53 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS11800 b21b7ae6952e1dae9ab95f20fe94baf7 313 Gene3D G3DSA:3.40.50.720 3 276 4.9E-43 T 29-03-2018 GBCGDNIH2_RS11800 b21b7ae6952e1dae9ab95f20fe94baf7 313 Pfam PF01370 NAD dependent epimerase/dehydratase family 7 214 2.6E-21 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 GBCGDNIH2_RS08735 69093c05169810bb7aeb9ebd7e092c80 443 Gene3D G3DSA:1.20.200.10 101 356 7.3E-74 T 29-03-2018 GBCGDNIH2_RS08735 69093c05169810bb7aeb9ebd7e092c80 443 Pfam PF10397 Adenylosuccinate lyase C-terminus 358 440 1.1E-23 T 29-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 GBCGDNIH2_RS08735 69093c05169810bb7aeb9ebd7e092c80 443 Pfam PF00206 Lyase 8 292 2.7E-52 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal GBCGDNIH2_RS08735 69093c05169810bb7aeb9ebd7e092c80 443 SMART SM00998 357 442 2.6E-33 T 29-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 GBCGDNIH2_RS08735 69093c05169810bb7aeb9ebd7e092c80 443 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 2 441 1.4E-144 T 29-03-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 GBCGDNIH2_RS08735 69093c05169810bb7aeb9ebd7e092c80 443 ProSitePatterns PS00163 Fumarate lyases signature. 269 278 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 GBCGDNIH2_RS08735 69093c05169810bb7aeb9ebd7e092c80 443 PRINTS PR00149 Fumarate lyase superfamily signature 269 285 6.6E-22 T 29-03-2018 IPR000362 Fumarate lyase family GBCGDNIH2_RS08735 69093c05169810bb7aeb9ebd7e092c80 443 PRINTS PR00149 Fumarate lyase superfamily signature 141 159 6.6E-22 T 29-03-2018 IPR000362 Fumarate lyase family GBCGDNIH2_RS08735 69093c05169810bb7aeb9ebd7e092c80 443 PRINTS PR00149 Fumarate lyase superfamily signature 96 114 6.6E-22 T 29-03-2018 IPR000362 Fumarate lyase family GBCGDNIH2_RS08735 69093c05169810bb7aeb9ebd7e092c80 443 PRINTS PR00149 Fumarate lyase superfamily signature 224 251 6.6E-22 T 29-03-2018 IPR000362 Fumarate lyase family GBCGDNIH2_RS08735 69093c05169810bb7aeb9ebd7e092c80 443 Gene3D G3DSA:1.10.275.10 1 98 3.1E-22 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal GBCGDNIH2_RS08735 69093c05169810bb7aeb9ebd7e092c80 443 Gene3D G3DSA:1.10.40.30 357 441 1.0E-22 T 29-03-2018 GBCGDNIH2_RS08735 69093c05169810bb7aeb9ebd7e092c80 443 SUPERFAMILY SSF48557 3 441 2.2E-124 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 GBCGDNIH2_RS08940 5e1ce467708ed6e8d873f8e2f893a795 104 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 101 8.7E-40 T 29-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS08940 5e1ce467708ed6e8d873f8e2f893a795 104 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 102 1.6E-33 T 29-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS08940 5e1ce467708ed6e8d873f8e2f893a795 104 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 103 26.026 T 29-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS08940 5e1ce467708ed6e8d873f8e2f893a795 104 SUPERFAMILY SSF141091 1 102 2.62E-36 T 29-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS10005 a1e4f28b9eb60ffa2c5dcaf2f0602509 258 Pfam PF00005 ABC transporter 27 170 2.0E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GBCGDNIH2_RS10005 a1e4f28b9eb60ffa2c5dcaf2f0602509 258 TIGRFAM TIGR03864 PQQ_ABC_ATP: ABC transporter, ATP-binding subunit, PQQ-dependent alcohol dehydrogenase system 11 246 2.0E-106 T 29-03-2018 IPR022467 ABC transporter, ATP-binding subunit, PQQ-dependent alcohol dehydrogenase system GBCGDNIH2_RS10005 a1e4f28b9eb60ffa2c5dcaf2f0602509 258 SUPERFAMILY SSF52540 11 233 7.14E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS10005 a1e4f28b9eb60ffa2c5dcaf2f0602509 258 SMART SM00382 36 219 1.1E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS10005 a1e4f28b9eb60ffa2c5dcaf2f0602509 258 Gene3D G3DSA:3.40.50.300 8 258 8.4E-62 T 29-03-2018 GBCGDNIH2_RS10005 a1e4f28b9eb60ffa2c5dcaf2f0602509 258 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GBCGDNIH2_RS03655 cbff9a87af1be53ce8df08923cd339bd 184 Gene3D G3DSA:1.20.1550.10 15 181 4.9E-23 T 29-03-2018 IPR023380 Disulphide bond formation protein DsbB-like domain GBCGDNIH2_RS03655 cbff9a87af1be53ce8df08923cd339bd 184 PIRSF PIRSF033913 2 183 1.7E-21 T 29-03-2018 IPR024199 Uncharacterised conserved protein, DsbB-like GBCGDNIH2_RS03655 cbff9a87af1be53ce8df08923cd339bd 184 SUPERFAMILY SSF158442 27 175 7.72E-22 T 29-03-2018 IPR023380 Disulphide bond formation protein DsbB-like domain GBCGDNIH2_RS03655 cbff9a87af1be53ce8df08923cd339bd 184 Pfam PF02600 Disulfide bond formation protein DsbB 24 173 1.9E-22 T 29-03-2018 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 GBCGDNIH2_RS08510 ac2c326b33b696238b24e48ed3f34570 587 Pfam PF13403 Hint domain 227 366 8.5E-39 T 29-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 GBCGDNIH2_RS08510 ac2c326b33b696238b24e48ed3f34570 587 Gene3D G3DSA:2.170.16.10 227 423 1.3E-16 T 29-03-2018 GBCGDNIH2_RS08510 ac2c326b33b696238b24e48ed3f34570 587 SUPERFAMILY SSF51294 228 363 1.78E-9 T 29-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 GBCGDNIH2_RS12415 e00774fbd6716f13a874916286743e52 507 SUPERFAMILY SSF69705 8 130 8.37E-37 T 29-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 GBCGDNIH2_RS12415 e00774fbd6716f13a874916286743e52 507 Gene3D G3DSA:1.10.150.20 431 503 2.0E-19 T 29-03-2018 GBCGDNIH2_RS12415 e00774fbd6716f13a874916286743e52 507 Gene3D G3DSA:1.10.150.20 356 425 2.5E-12 T 29-03-2018 GBCGDNIH2_RS12415 e00774fbd6716f13a874916286743e52 507 SUPERFAMILY SSF54814 204 281 3.92E-31 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 GBCGDNIH2_RS12415 e00774fbd6716f13a874916286743e52 507 Pfam PF08529 NusA N-terminal domain 9 128 8.7E-33 T 29-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 GBCGDNIH2_RS12415 e00774fbd6716f13a874916286743e52 507 SUPERFAMILY SSF47794 353 414 2.51E-15 T 29-03-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 GBCGDNIH2_RS12415 e00774fbd6716f13a874916286743e52 507 SMART SM00316 138 204 5.8E-8 T 29-03-2018 IPR022967 RNA-binding domain, S1 GBCGDNIH2_RS12415 e00774fbd6716f13a874916286743e52 507 Pfam PF13184 NusA-like KH domain 234 300 2.5E-27 T 29-03-2018 IPR025249 KH domain, NusA-like GO:0003723 GBCGDNIH2_RS12415 e00774fbd6716f13a874916286743e52 507 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 7 415 30.141 T 29-03-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 GBCGDNIH2_RS12415 e00774fbd6716f13a874916286743e52 507 Pfam PF00575 S1 RNA binding domain 136 197 4.1E-6 T 29-03-2018 IPR003029 S1 domain GO:0003676 GBCGDNIH2_RS12415 e00774fbd6716f13a874916286743e52 507 Gene3D G3DSA:3.30.300.20 203 280 2.7E-35 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta GBCGDNIH2_RS12415 e00774fbd6716f13a874916286743e52 507 SUPERFAMILY SSF50249 136 203 5.8E-19 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold GBCGDNIH2_RS12415 e00774fbd6716f13a874916286743e52 507 SUPERFAMILY SSF54814 285 346 5.23E-16 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 GBCGDNIH2_RS12415 e00774fbd6716f13a874916286743e52 507 Gene3D G3DSA:3.30.1480.10 7 133 8.7E-43 T 29-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 GBCGDNIH2_RS12415 e00774fbd6716f13a874916286743e52 507 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 10 346 1.7E-131 T 29-03-2018 IPR010213 Transcription termination factor NusA GO:0003723 GBCGDNIH2_RS12415 e00774fbd6716f13a874916286743e52 507 SUPERFAMILY SSF47794 433 499 5.97E-12 T 29-03-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 GBCGDNIH2_RS12415 e00774fbd6716f13a874916286743e52 507 Gene3D G3DSA:2.40.50.140 134 202 1.2E-15 T 29-03-2018 GBCGDNIH2_RS12415 e00774fbd6716f13a874916286743e52 507 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 369 414 5.6E-16 T 29-03-2018 IPR010214 Transcription termination factor NusA, C-terminal duplication GBCGDNIH2_RS12415 e00774fbd6716f13a874916286743e52 507 SMART SM00322 305 418 4.9E-4 T 29-03-2018 IPR004087 K Homology domain GO:0003676 GBCGDNIH2_RS12415 e00774fbd6716f13a874916286743e52 507 SMART SM00322 234 297 9.8 T 29-03-2018 IPR004087 K Homology domain GO:0003676 GBCGDNIH2_RS12415 e00774fbd6716f13a874916286743e52 507 Pfam PF14520 Helix-hairpin-helix domain 437 493 2.6E-6 T 29-03-2018 GBCGDNIH2_RS12415 e00774fbd6716f13a874916286743e52 507 Pfam PF14520 Helix-hairpin-helix domain 373 413 6.7E-4 T 29-03-2018 GBCGDNIH2_RS12415 e00774fbd6716f13a874916286743e52 507 Gene3D G3DSA:3.30.300.20 282 352 2.9E-15 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta GBCGDNIH2_RS07165 80a3cae91dc3f0603ad54b99868919ee 212 Pfam PF13628 Domain of unknown function (DUF4142) 36 171 3.2E-35 T 29-03-2018 IPR025419 Domain of unknown function DUF4142 GBCGDNIH2_RS07165 80a3cae91dc3f0603ad54b99868919ee 212 Gene3D G3DSA:1.20.1260.10 26 173 5.2E-21 T 29-03-2018 IPR012347 Ferritin-related GBCGDNIH2_RS03700 f0e5f5bba1fdd4d97d3ff0c1e1f16eb9 44 ProSitePatterns PS00784 Ribosomal protein L34 signature. 2 21 - T 29-03-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS03700 f0e5f5bba1fdd4d97d3ff0c1e1f16eb9 44 Pfam PF00468 Ribosomal protein L34 2 44 1.0E-23 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS03700 f0e5f5bba1fdd4d97d3ff0c1e1f16eb9 44 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 2 44 7.7E-24 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS03700 f0e5f5bba1fdd4d97d3ff0c1e1f16eb9 44 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 15.646 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS03700 f0e5f5bba1fdd4d97d3ff0c1e1f16eb9 44 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 1 42 6.0E-13 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS10890 fce77f74e2b35098b5af5baa6f7d9cd7 323 SUPERFAMILY SSF48179 217 316 7.57E-33 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 GBCGDNIH2_RS10890 fce77f74e2b35098b5af5baa6f7d9cd7 323 Gene3D G3DSA:3.40.50.720 15 216 6.7E-55 T 29-03-2018 GBCGDNIH2_RS10890 fce77f74e2b35098b5af5baa6f7d9cd7 323 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 37 214 4.4E-60 T 29-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 GBCGDNIH2_RS10890 fce77f74e2b35098b5af5baa6f7d9cd7 323 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 219 314 2.5E-34 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 GBCGDNIH2_RS10890 fce77f74e2b35098b5af5baa6f7d9cd7 323 Gene3D G3DSA:1.10.1040.10 217 318 8.9E-35 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 GBCGDNIH2_RS10890 fce77f74e2b35098b5af5baa6f7d9cd7 323 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 215 240 - T 29-03-2018 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 GBCGDNIH2_RS10890 fce77f74e2b35098b5af5baa6f7d9cd7 323 SUPERFAMILY SSF51735 34 217 4.72E-57 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS10890 fce77f74e2b35098b5af5baa6f7d9cd7 323 PIRSF PIRSF000105 30 323 8.2E-85 T 29-03-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 GBCGDNIH2_RS08140 8dbda0c1773fd4715750bea4096f67f4 526 Pfam PF05050 Methyltransferase FkbM domain 60 221 3.8E-13 T 29-03-2018 IPR006342 Methyltransferase FkbM GBCGDNIH2_RS08140 8dbda0c1773fd4715750bea4096f67f4 526 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 57 202 4.2E-21 T 29-03-2018 IPR006342 Methyltransferase FkbM GBCGDNIH2_RS08140 8dbda0c1773fd4715750bea4096f67f4 526 SUPERFAMILY SSF53335 29 223 1.74E-41 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GBCGDNIH2_RS08140 8dbda0c1773fd4715750bea4096f67f4 526 Gene3D G3DSA:3.40.50.150 48 234 3.5E-27 T 29-03-2018 GBCGDNIH2_RS07600 b7d2b97b7719884f0771431ee494c53a 459 Gene3D G3DSA:3.30.390.30 343 458 1.2E-35 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 GBCGDNIH2_RS07600 b7d2b97b7719884f0771431ee494c53a 459 PIRSF PIRSF000350 1 449 2.5E-84 T 29-03-2018 GBCGDNIH2_RS07600 b7d2b97b7719884f0771431ee494c53a 459 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 344 451 1.1E-32 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 GBCGDNIH2_RS07600 b7d2b97b7719884f0771431ee494c53a 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 287 309 1.3E-29 T 29-03-2018 GBCGDNIH2_RS07600 b7d2b97b7719884f0771431ee494c53a 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.3E-29 T 29-03-2018 GBCGDNIH2_RS07600 b7d2b97b7719884f0771431ee494c53a 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 173 191 1.3E-29 T 29-03-2018 GBCGDNIH2_RS07600 b7d2b97b7719884f0771431ee494c53a 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 274 1.3E-29 T 29-03-2018 GBCGDNIH2_RS07600 b7d2b97b7719884f0771431ee494c53a 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 136 154 1.3E-29 T 29-03-2018 GBCGDNIH2_RS07600 b7d2b97b7719884f0771431ee494c53a 459 SUPERFAMILY SSF55424 342 452 2.92E-33 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 GBCGDNIH2_RS07600 b7d2b97b7719884f0771431ee494c53a 459 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 29-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 GBCGDNIH2_RS07600 b7d2b97b7719884f0771431ee494c53a 459 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 322 9.7E-64 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS07600 b7d2b97b7719884f0771431ee494c53a 459 Gene3D G3DSA:3.50.50.60 1 154 1.8E-28 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS07600 b7d2b97b7719884f0771431ee494c53a 459 SUPERFAMILY SSF51905 5 365 3.63E-52 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS07600 b7d2b97b7719884f0771431ee494c53a 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 302 309 5.3E-66 T 29-03-2018 GBCGDNIH2_RS07600 b7d2b97b7719884f0771431ee494c53a 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 426 446 5.3E-66 T 29-03-2018 GBCGDNIH2_RS07600 b7d2b97b7719884f0771431ee494c53a 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 404 419 5.3E-66 T 29-03-2018 GBCGDNIH2_RS07600 b7d2b97b7719884f0771431ee494c53a 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 173 198 5.3E-66 T 29-03-2018 GBCGDNIH2_RS07600 b7d2b97b7719884f0771431ee494c53a 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 340 361 5.3E-66 T 29-03-2018 GBCGDNIH2_RS07600 b7d2b97b7719884f0771431ee494c53a 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 259 273 5.3E-66 T 29-03-2018 GBCGDNIH2_RS07600 b7d2b97b7719884f0771431ee494c53a 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 5.3E-66 T 29-03-2018 GBCGDNIH2_RS07600 b7d2b97b7719884f0771431ee494c53a 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 139 148 5.3E-66 T 29-03-2018 GBCGDNIH2_RS07600 b7d2b97b7719884f0771431ee494c53a 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 5.3E-66 T 29-03-2018 GBCGDNIH2_RS07600 b7d2b97b7719884f0771431ee494c53a 459 Gene3D G3DSA:3.50.50.60 275 332 6.7E-11 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS07600 b7d2b97b7719884f0771431ee494c53a 459 Gene3D G3DSA:3.50.50.60 155 274 3.0E-27 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS00920 318a71b6a1272464f8bffc5bbe9aea27 676 SUPERFAMILY SSF81665 41 94 3.79E-7 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 GBCGDNIH2_RS00920 318a71b6a1272464f8bffc5bbe9aea27 676 SUPERFAMILY SSF81665 204 295 3.79E-7 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 GBCGDNIH2_RS00920 318a71b6a1272464f8bffc5bbe9aea27 676 Gene3D G3DSA:3.40.1110.10 312 437 1.6E-22 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 GBCGDNIH2_RS00920 318a71b6a1272464f8bffc5bbe9aea27 676 Gene3D G3DSA:2.70.150.10 23 204 2.7E-24 T 29-03-2018 GBCGDNIH2_RS00920 318a71b6a1272464f8bffc5bbe9aea27 676 Pfam PF00702 haloacid dehalogenase-like hydrolase 297 524 2.1E-30 T 29-03-2018 GBCGDNIH2_RS00920 318a71b6a1272464f8bffc5bbe9aea27 676 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 303 309 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 GBCGDNIH2_RS00920 318a71b6a1272464f8bffc5bbe9aea27 676 Pfam PF00122 E1-E2 ATPase 112 279 2.8E-31 T 29-03-2018 GBCGDNIH2_RS00920 318a71b6a1272464f8bffc5bbe9aea27 676 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 301 315 4.0E-23 T 29-03-2018 GBCGDNIH2_RS00920 318a71b6a1272464f8bffc5bbe9aea27 676 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 533 545 4.0E-23 T 29-03-2018 GBCGDNIH2_RS00920 318a71b6a1272464f8bffc5bbe9aea27 676 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 457 467 4.0E-23 T 29-03-2018 GBCGDNIH2_RS00920 318a71b6a1272464f8bffc5bbe9aea27 676 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 150 164 4.0E-23 T 29-03-2018 GBCGDNIH2_RS00920 318a71b6a1272464f8bffc5bbe9aea27 676 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 510 529 4.0E-23 T 29-03-2018 GBCGDNIH2_RS00920 318a71b6a1272464f8bffc5bbe9aea27 676 Gene3D G3DSA:3.40.50.1000 438 567 2.9E-31 T 29-03-2018 IPR023214 HAD-like domain GBCGDNIH2_RS00920 318a71b6a1272464f8bffc5bbe9aea27 676 SUPERFAMILY SSF81653 112 203 5.89E-22 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 GBCGDNIH2_RS00920 318a71b6a1272464f8bffc5bbe9aea27 676 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 368 593 6.6E-45 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 GBCGDNIH2_RS00920 318a71b6a1272464f8bffc5bbe9aea27 676 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 63 335 1.6E-29 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 GBCGDNIH2_RS00920 318a71b6a1272464f8bffc5bbe9aea27 676 SUPERFAMILY SSF56784 289 313 3.38E-36 T 29-03-2018 IPR023214 HAD-like domain GBCGDNIH2_RS00920 318a71b6a1272464f8bffc5bbe9aea27 676 SUPERFAMILY SSF56784 373 400 3.38E-36 T 29-03-2018 IPR023214 HAD-like domain GBCGDNIH2_RS00920 318a71b6a1272464f8bffc5bbe9aea27 676 SUPERFAMILY SSF56784 429 553 3.38E-36 T 29-03-2018 IPR023214 HAD-like domain GBCGDNIH2_RS00920 318a71b6a1272464f8bffc5bbe9aea27 676 ProSitePatterns PS01229 Hypothetical cof family signature 2. 510 532 - T 29-03-2018 GBCGDNIH2_RS00920 318a71b6a1272464f8bffc5bbe9aea27 676 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 4 670 0.0 T 29-03-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 GBCGDNIH2_RS00920 318a71b6a1272464f8bffc5bbe9aea27 676 SUPERFAMILY SSF81660 313 444 2.42E-32 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 GBCGDNIH2_RS00920 318a71b6a1272464f8bffc5bbe9aea27 676 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 1 674 41.191 T 29-03-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 GBCGDNIH2_RS03305 f6e6f11148b3f219e1d168dea14e500e 262 Gene3D G3DSA:3.40.50.1820 7 258 2.1E-31 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS03305 f6e6f11148b3f219e1d168dea14e500e 262 SUPERFAMILY SSF53474 13 251 1.37E-36 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS03305 f6e6f11148b3f219e1d168dea14e500e 262 Pfam PF12146 Serine aminopeptidase, S33 32 139 4.2E-11 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 GBCGDNIH2_RS01170 1b04b9aa50b02dc56261658fa75169fa 1060 Pfam PF00873 AcrB/AcrD/AcrF family 7 1049 6.0E-180 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS01170 1b04b9aa50b02dc56261658fa75169fa 1060 SUPERFAMILY SSF82693 41 136 8.89E-15 T 29-03-2018 GBCGDNIH2_RS01170 1b04b9aa50b02dc56261658fa75169fa 1060 SUPERFAMILY SSF82693 269 323 1.15E-13 T 29-03-2018 GBCGDNIH2_RS01170 1b04b9aa50b02dc56261658fa75169fa 1060 SUPERFAMILY SSF82693 137 183 1.15E-13 T 29-03-2018 GBCGDNIH2_RS01170 1b04b9aa50b02dc56261658fa75169fa 1060 Gene3D G3DSA:1.20.1640.10 282 498 9.6E-35 T 29-03-2018 GBCGDNIH2_RS01170 1b04b9aa50b02dc56261658fa75169fa 1060 Gene3D G3DSA:1.20.1640.10 850 1060 2.4E-28 T 29-03-2018 GBCGDNIH2_RS01170 1b04b9aa50b02dc56261658fa75169fa 1060 Gene3D G3DSA:3.30.2090.10 183 269 1.1E-9 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains GBCGDNIH2_RS01170 1b04b9aa50b02dc56261658fa75169fa 1060 SUPERFAMILY SSF82866 292 490 2.22E-38 T 29-03-2018 GBCGDNIH2_RS01170 1b04b9aa50b02dc56261658fa75169fa 1060 SUPERFAMILY SSF82714 186 265 5.49E-11 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains GBCGDNIH2_RS01170 1b04b9aa50b02dc56261658fa75169fa 1060 SUPERFAMILY SSF82866 834 1053 3.27E-40 T 29-03-2018 GBCGDNIH2_RS01170 1b04b9aa50b02dc56261658fa75169fa 1060 PRINTS PR00702 Acriflavin resistance protein family signature 464 487 1.1E-35 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS01170 1b04b9aa50b02dc56261658fa75169fa 1060 PRINTS PR00702 Acriflavin resistance protein family signature 11 35 1.1E-35 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS01170 1b04b9aa50b02dc56261658fa75169fa 1060 PRINTS PR00702 Acriflavin resistance protein family signature 386 410 1.1E-35 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS01170 1b04b9aa50b02dc56261658fa75169fa 1060 PRINTS PR00702 Acriflavin resistance protein family signature 331 354 1.1E-35 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS01170 1b04b9aa50b02dc56261658fa75169fa 1060 PRINTS PR00702 Acriflavin resistance protein family signature 439 462 1.1E-35 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS01170 1b04b9aa50b02dc56261658fa75169fa 1060 PRINTS PR00702 Acriflavin resistance protein family signature 358 379 1.1E-35 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS01170 1b04b9aa50b02dc56261658fa75169fa 1060 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 1.1E-35 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS01170 1b04b9aa50b02dc56261658fa75169fa 1060 Gene3D G3DSA:3.30.70.1430 41 143 4.4E-15 T 29-03-2018 GBCGDNIH2_RS01115 a89cfd5fcb228b3de24e553e77ee65d5 309 SUPERFAMILY SSF48576 21 302 2.09E-79 T 29-03-2018 IPR008949 Isoprenoid synthase domain GBCGDNIH2_RS01115 a89cfd5fcb228b3de24e553e77ee65d5 309 Pfam PF00348 Polyprenyl synthetase 46 279 2.8E-56 T 29-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 GBCGDNIH2_RS01115 a89cfd5fcb228b3de24e553e77ee65d5 309 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 228 240 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site GBCGDNIH2_RS01115 a89cfd5fcb228b3de24e553e77ee65d5 309 Gene3D G3DSA:1.10.600.10 6 309 3.0E-84 T 29-03-2018 IPR008949 Isoprenoid synthase domain GBCGDNIH2_RS01115 a89cfd5fcb228b3de24e553e77ee65d5 309 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 96 112 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site GBCGDNIH2_RS08030 38b77728c0060fa01691c331359a945a 526 Pfam PF10412 Type IV secretion-system coupling protein DNA-binding domain 172 501 8.1E-102 T 29-03-2018 IPR019476 Type IV secretion system coupling protein TraD, DNA-binding domain GBCGDNIH2_RS08030 38b77728c0060fa01691c331359a945a 526 SUPERFAMILY SSF52540 177 498 2.51E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS08030 38b77728c0060fa01691c331359a945a 526 Gene3D G3DSA:3.40.50.300 133 508 2.2E-31 T 29-03-2018 GBCGDNIH2_RS10870 a5b6856e79657252e33a200817b9fb83 68 Gene3D G3DSA:3.30.70.100 1 68 1.8E-16 T 29-03-2018 GBCGDNIH2_RS10870 a5b6856e79657252e33a200817b9fb83 68 ProSitePatterns PS01047 Heavy-metal-associated domain. 9 38 - T 29-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 GBCGDNIH2_RS10870 a5b6856e79657252e33a200817b9fb83 68 Pfam PF00403 Heavy-metal-associated domain 7 60 2.7E-10 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 GBCGDNIH2_RS10870 a5b6856e79657252e33a200817b9fb83 68 SUPERFAMILY SSF55008 4 65 6.81E-14 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 GBCGDNIH2_RS01880 bc78b780f263c3591374d9fd3fb66954 475 SUPERFAMILY SSF52935 324 474 2.09E-37 T 29-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 GBCGDNIH2_RS01880 bc78b780f263c3591374d9fd3fb66954 475 PRINTS PR01050 Pyruvate kinase family signature 191 205 3.7E-64 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 GBCGDNIH2_RS01880 bc78b780f263c3591374d9fd3fb66954 475 PRINTS PR01050 Pyruvate kinase family signature 314 330 3.7E-64 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 GBCGDNIH2_RS01880 bc78b780f263c3591374d9fd3fb66954 475 PRINTS PR01050 Pyruvate kinase family signature 245 269 3.7E-64 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 GBCGDNIH2_RS01880 bc78b780f263c3591374d9fd3fb66954 475 PRINTS PR01050 Pyruvate kinase family signature 218 244 3.7E-64 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 GBCGDNIH2_RS01880 bc78b780f263c3591374d9fd3fb66954 475 PRINTS PR01050 Pyruvate kinase family signature 270 294 3.7E-64 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 GBCGDNIH2_RS01880 bc78b780f263c3591374d9fd3fb66954 475 PRINTS PR01050 Pyruvate kinase family signature 295 313 3.7E-64 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 GBCGDNIH2_RS01880 bc78b780f263c3591374d9fd3fb66954 475 PRINTS PR01050 Pyruvate kinase family signature 66 82 3.7E-64 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 GBCGDNIH2_RS01880 bc78b780f263c3591374d9fd3fb66954 475 Gene3D G3DSA:3.20.20.60 165 322 7.6E-62 T 29-03-2018 GBCGDNIH2_RS01880 bc78b780f263c3591374d9fd3fb66954 475 Gene3D G3DSA:3.20.20.60 2 114 1.8E-19 T 29-03-2018 GBCGDNIH2_RS01880 bc78b780f263c3591374d9fd3fb66954 475 SUPERFAMILY SSF50800 77 172 6.11E-25 T 29-03-2018 IPR011037 Pyruvate kinase-like, insert domain GBCGDNIH2_RS01880 bc78b780f263c3591374d9fd3fb66954 475 SUPERFAMILY SSF51621 161 342 6.28E-99 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 GBCGDNIH2_RS01880 bc78b780f263c3591374d9fd3fb66954 475 SUPERFAMILY SSF51621 4 81 6.28E-99 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 GBCGDNIH2_RS01880 bc78b780f263c3591374d9fd3fb66954 475 Gene3D G3DSA:3.40.1380.20 323 475 1.6E-47 T 29-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 GBCGDNIH2_RS01880 bc78b780f263c3591374d9fd3fb66954 475 Gene3D G3DSA:2.40.33.10 115 164 4.5E-20 T 29-03-2018 GBCGDNIH2_RS01880 bc78b780f263c3591374d9fd3fb66954 475 Pfam PF00224 Pyruvate kinase, barrel domain 9 338 6.7E-116 T 29-03-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 GBCGDNIH2_RS01880 bc78b780f263c3591374d9fd3fb66954 475 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 9 474 2.9E-155 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 GBCGDNIH2_RS01880 bc78b780f263c3591374d9fd3fb66954 475 Pfam PF02887 Pyruvate kinase, alpha/beta domain 359 471 2.9E-31 T 29-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 GBCGDNIH2_RS00270 6cb1816cd06ba84047acae8746fdf709 926 Gene3D G3DSA:1.20.1440.90 280 409 9.9E-15 T 29-03-2018 GBCGDNIH2_RS00270 6cb1816cd06ba84047acae8746fdf709 926 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 575 595 1.0E-52 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 GBCGDNIH2_RS00270 6cb1816cd06ba84047acae8746fdf709 926 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 251 266 1.0E-52 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 GBCGDNIH2_RS00270 6cb1816cd06ba84047acae8746fdf709 926 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 187 203 1.0E-52 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 GBCGDNIH2_RS00270 6cb1816cd06ba84047acae8746fdf709 926 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 754 780 1.0E-52 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 GBCGDNIH2_RS00270 6cb1816cd06ba84047acae8746fdf709 926 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 134 147 1.0E-52 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 GBCGDNIH2_RS00270 6cb1816cd06ba84047acae8746fdf709 926 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 617 646 1.0E-52 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 GBCGDNIH2_RS00270 6cb1816cd06ba84047acae8746fdf709 926 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 407 427 1.0E-52 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 GBCGDNIH2_RS00270 6cb1816cd06ba84047acae8746fdf709 926 Pfam PF00311 Phosphoenolpyruvate carboxylase 130 926 5.8E-222 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 GBCGDNIH2_RS00270 6cb1816cd06ba84047acae8746fdf709 926 SUPERFAMILY SSF51621 28 926 4.87E-254 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 GBCGDNIH2_RS00270 6cb1816cd06ba84047acae8746fdf709 926 ProSitePatterns PS00393 Phosphoenolpyruvate carboxylase active site 2. 577 589 - T 29-03-2018 IPR033129 Phosphoenolpyruvate carboxylase, His active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 GBCGDNIH2_RS09560 2585db747ca9818fb4aac64f9a86cf84 369 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 269 355 1.5E-14 T 29-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 GBCGDNIH2_RS09560 2585db747ca9818fb4aac64f9a86cf84 369 Gene3D G3DSA:4.10.1250.10 230 282 5.8E-7 T 29-03-2018 GBCGDNIH2_RS09560 2585db747ca9818fb4aac64f9a86cf84 369 Gene3D G3DSA:3.30.1360.120 8 129 4.2E-17 T 29-03-2018 GBCGDNIH2_RS09560 2585db747ca9818fb4aac64f9a86cf84 369 Gene3D G3DSA:3.30.1360.120 130 229 5.3E-18 T 29-03-2018 GBCGDNIH2_RS09560 2585db747ca9818fb4aac64f9a86cf84 369 PIRSF PIRSF006487 2 369 5.9E-86 T 29-03-2018 GBCGDNIH2_RS09560 2585db747ca9818fb4aac64f9a86cf84 369 SUPERFAMILY SSF101790 287 366 1.13E-15 T 29-03-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain GBCGDNIH2_RS09560 2585db747ca9818fb4aac64f9a86cf84 369 SUPERFAMILY SSF103025 6 279 1.7E-70 T 29-03-2018 GBCGDNIH2_RS09560 2585db747ca9818fb4aac64f9a86cf84 369 Gene3D G3DSA:2.40.30.110 283 368 1.0E-15 T 29-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 GBCGDNIH2_RS09560 2585db747ca9818fb4aac64f9a86cf84 369 Pfam PF01571 Aminomethyltransferase folate-binding domain 12 261 8.8E-67 T 29-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal GBCGDNIH2_RS10805 44a7fdd95bcbf68bc1975d2e00d77040 433 SUPERFAMILY SSF103473 10 428 1.57E-64 T 29-03-2018 IPR020846 Major facilitator superfamily domain GBCGDNIH2_RS10805 44a7fdd95bcbf68bc1975d2e00d77040 433 ProSitePatterns PS00217 Sugar transport proteins signature 2. 126 151 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 GBCGDNIH2_RS10805 44a7fdd95bcbf68bc1975d2e00d77040 433 Gene3D G3DSA:1.20.1250.20 224 433 4.6E-25 T 29-03-2018 GBCGDNIH2_RS10805 44a7fdd95bcbf68bc1975d2e00d77040 433 Pfam PF00083 Sugar (and other) transporter 23 226 1.6E-28 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 GBCGDNIH2_RS10805 44a7fdd95bcbf68bc1975d2e00d77040 433 Pfam PF00083 Sugar (and other) transporter 230 429 1.4E-13 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 GBCGDNIH2_RS10805 44a7fdd95bcbf68bc1975d2e00d77040 433 Gene3D G3DSA:1.20.1250.20 5 223 2.0E-28 T 29-03-2018 GBCGDNIH2_RS06045 51553f0c31ee1aa6521be76dfa6dd72e 378 Gene3D G3DSA:2.30.40.10 1 55 4.6E-12 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 GBCGDNIH2_RS06045 51553f0c31ee1aa6521be76dfa6dd72e 378 SUPERFAMILY SSF51556 217 344 2.53E-13 T 29-03-2018 IPR032466 Metal-dependent hydrolase GBCGDNIH2_RS06045 51553f0c31ee1aa6521be76dfa6dd72e 378 SUPERFAMILY SSF51556 53 180 2.53E-13 T 29-03-2018 IPR032466 Metal-dependent hydrolase GBCGDNIH2_RS06045 51553f0c31ee1aa6521be76dfa6dd72e 378 TIGRFAM TIGR02318 phosphono_phnM: phosphonate metabolism protein PhnM 5 377 8.7E-128 T 29-03-2018 IPR012696 Phosphonate metabolism PhnM GO:0019700 KEGG: 00440+3.6.1.63|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 GBCGDNIH2_RS06045 51553f0c31ee1aa6521be76dfa6dd72e 378 Gene3D G3DSA:3.20.20.140 56 376 1.7E-22 T 29-03-2018 GBCGDNIH2_RS06045 51553f0c31ee1aa6521be76dfa6dd72e 378 Pfam PF07969 Amidohydrolase family 287 358 1.1E-10 T 29-03-2018 IPR013108 Amidohydrolase 3 GBCGDNIH2_RS06045 51553f0c31ee1aa6521be76dfa6dd72e 378 PIRSF PIRSF038971 2 378 1.2E-137 T 29-03-2018 IPR012696 Phosphonate metabolism PhnM GO:0019700 KEGG: 00440+3.6.1.63|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 GBCGDNIH2_RS06045 51553f0c31ee1aa6521be76dfa6dd72e 378 SUPERFAMILY SSF51338 2 53 1.21E-15 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 GBCGDNIH2_RS06045 51553f0c31ee1aa6521be76dfa6dd72e 378 SUPERFAMILY SSF51338 345 377 1.21E-15 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 GBCGDNIH2_RS12460 4adc0a50ce4aeebd69be60aac5501bb1 212 TIGRFAM TIGR03481 HpnM: hopanoid biosynthesis associated membrane protein HpnM 17 206 2.2E-54 T 29-03-2018 IPR017842 Hopanoid biosynthesis-associated membrane protein HpnM GBCGDNIH2_RS12460 4adc0a50ce4aeebd69be60aac5501bb1 212 Gene3D G3DSA:3.10.450.50 83 174 1.2E-16 T 29-03-2018 GBCGDNIH2_RS12460 4adc0a50ce4aeebd69be60aac5501bb1 212 Pfam PF05494 MlaC protein 45 202 1.4E-33 T 29-03-2018 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC GBCGDNIH2_RS04165 90c75280168d410aa15b4fb388acb927 316 SUPERFAMILY SSF53850 90 302 3.57E-47 T 29-03-2018 GBCGDNIH2_RS04165 90c75280168d410aa15b4fb388acb927 316 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 2.8E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS04165 90c75280168d410aa15b4fb388acb927 316 Gene3D G3DSA:1.10.10.10 3 84 3.5E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS04165 90c75280168d410aa15b4fb388acb927 316 SUPERFAMILY SSF46785 6 87 1.1E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS04165 90c75280168d410aa15b4fb388acb927 316 Gene3D G3DSA:3.40.190.10 88 175 1.9E-15 T 29-03-2018 GBCGDNIH2_RS04165 90c75280168d410aa15b4fb388acb927 316 Pfam PF03466 LysR substrate binding domain 88 297 1.2E-46 T 29-03-2018 IPR005119 LysR, substrate-binding GBCGDNIH2_RS04165 90c75280168d410aa15b4fb388acb927 316 Gene3D G3DSA:3.40.190.10 176 264 9.7E-28 T 29-03-2018 GBCGDNIH2_RS10195 f8d66c63cf1171f6f4b7eb59ed677ed2 484 PIRSF PIRSF006060 22 481 4.1E-88 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 GBCGDNIH2_RS10195 f8d66c63cf1171f6f4b7eb59ed677ed2 484 Pfam PF13520 Amino acid permease 37 442 1.4E-51 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 GBCGDNIH2_RS07665 412955ba26fa30f6b58900f22a3f5576 452 SUPERFAMILY SSF53955 77 199 6.14E-35 T 29-03-2018 IPR023346 Lysozyme-like domain GBCGDNIH2_RS07665 412955ba26fa30f6b58900f22a3f5576 452 Pfam PF01464 Transglycosylase SLT domain 83 186 8.4E-24 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 GBCGDNIH2_RS07665 412955ba26fa30f6b58900f22a3f5576 452 Gene3D G3DSA:3.30.70.1070 365 451 2.0E-12 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 GBCGDNIH2_RS07665 412955ba26fa30f6b58900f22a3f5576 452 Pfam PF05036 Sporulation related domain 368 449 7.9E-10 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 GBCGDNIH2_RS07665 412955ba26fa30f6b58900f22a3f5576 452 Gene3D G3DSA:1.10.530.10 65 204 5.7E-35 T 29-03-2018 GBCGDNIH2_RS03155 991cbc52051331433e5ad06cfc26839a 327 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 12 323 46.155 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 GBCGDNIH2_RS03155 991cbc52051331433e5ad06cfc26839a 327 Gene3D G3DSA:3.90.226.10 2 284 2.3E-61 T 29-03-2018 GBCGDNIH2_RS03155 991cbc52051331433e5ad06cfc26839a 327 SUPERFAMILY SSF52096 13 322 2.7E-94 T 29-03-2018 IPR029045 ClpP/crotonase-like domain GBCGDNIH2_RS03155 991cbc52051331433e5ad06cfc26839a 327 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 95 106 4.7E-37 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 GBCGDNIH2_RS03155 991cbc52051331433e5ad06cfc26839a 327 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 141 157 4.7E-37 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 GBCGDNIH2_RS03155 991cbc52051331433e5ad06cfc26839a 327 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 160 173 4.7E-37 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 GBCGDNIH2_RS03155 991cbc52051331433e5ad06cfc26839a 327 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 176 189 4.7E-37 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 GBCGDNIH2_RS03155 991cbc52051331433e5ad06cfc26839a 327 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 204 213 4.7E-37 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 GBCGDNIH2_RS03155 991cbc52051331433e5ad06cfc26839a 327 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 120 138 4.7E-37 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 GBCGDNIH2_RS03155 991cbc52051331433e5ad06cfc26839a 327 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 13 154 4.4E-59 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 GBCGDNIH2_RS03155 991cbc52051331433e5ad06cfc26839a 327 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 9 323 1.4E-121 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 GBCGDNIH2_RS03245 bae6a10638e685a0febe7d24890b37cd 113 SUPERFAMILY SSF69118 6 107 1.44E-28 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 GBCGDNIH2_RS03245 bae6a10638e685a0febe7d24890b37cd 113 Pfam PF02627 Carboxymuconolactone decarboxylase family 34 105 1.2E-19 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 GBCGDNIH2_RS03245 bae6a10638e685a0febe7d24890b37cd 113 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 41 90 1.4E-19 T 29-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 GBCGDNIH2_RS03245 bae6a10638e685a0febe7d24890b37cd 113 Gene3D G3DSA:1.20.1290.10 3 113 2.0E-24 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 GBCGDNIH2_RS02715 929b01a909bf8c267aebf14a6ee53f7b 205 SUPERFAMILY SSF55174 5 205 4.19E-64 T 29-03-2018 GBCGDNIH2_RS02715 929b01a909bf8c267aebf14a6ee53f7b 205 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 6 93 9.7E-26 T 29-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 GBCGDNIH2_RS02715 929b01a909bf8c267aebf14a6ee53f7b 205 Gene3D G3DSA:1.10.1050.10 150 205 3.3E-13 T 29-03-2018 GBCGDNIH2_RS02715 929b01a909bf8c267aebf14a6ee53f7b 205 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 5 205 5.6E-76 T 29-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 GBCGDNIH2_RS02715 929b01a909bf8c267aebf14a6ee53f7b 205 SMART SM00363 94 158 3.6E-19 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 GBCGDNIH2_RS02715 929b01a909bf8c267aebf14a6ee53f7b 205 ProSitePatterns PS00632 Ribosomal protein S4 signature. 92 116 - T 29-03-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02715 929b01a909bf8c267aebf14a6ee53f7b 205 SMART SM01390 3 93 3.3E-42 T 29-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 GBCGDNIH2_RS02715 929b01a909bf8c267aebf14a6ee53f7b 205 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 205 33.008 T 29-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 GBCGDNIH2_RS02715 929b01a909bf8c267aebf14a6ee53f7b 205 Gene3D G3DSA:3.10.290.10 99 149 1.5E-20 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 GBCGDNIH2_RS02715 929b01a909bf8c267aebf14a6ee53f7b 205 Pfam PF01479 S4 domain 94 141 1.1E-19 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 GBCGDNIH2_RS02715 929b01a909bf8c267aebf14a6ee53f7b 205 Gene3D G3DSA:1.10.1050.10 1 98 4.7E-39 T 29-03-2018 GBCGDNIH2_RS06185 174dbe17a953ea900a6661b1cd0cbf35 230 Gene3D G3DSA:3.40.50.150 17 229 1.6E-61 T 29-03-2018 GBCGDNIH2_RS06185 174dbe17a953ea900a6661b1cd0cbf35 230 SUPERFAMILY SSF53335 19 226 1.3E-43 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GBCGDNIH2_RS06185 174dbe17a953ea900a6661b1cd0cbf35 230 Hamap MF_01547 Ribosomal RNA large subunit methyltransferase E [rlmE]. 34 224 30.584 T 29-03-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 KEGG: 00564+2.1.1.16 GBCGDNIH2_RS06185 174dbe17a953ea900a6661b1cd0cbf35 230 PIRSF PIRSF005461 16 230 3.7E-76 T 29-03-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 KEGG: 00564+2.1.1.16 GBCGDNIH2_RS06185 174dbe17a953ea900a6661b1cd0cbf35 230 Pfam PF01728 FtsJ-like methyltransferase 50 223 7.8E-57 T 29-03-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 GBCGDNIH2_RS07900 7bee35560b6e2cb178da494546b2cfe0 293 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 279 3.2E-30 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS07900 7bee35560b6e2cb178da494546b2cfe0 293 Gene3D G3DSA:1.10.3470.10 1 280 2.4E-39 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like GBCGDNIH2_RS06935 6e4fa670f20315c6d839a605d77682ca 162 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 102 113 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site GBCGDNIH2_RS06935 6e4fa670f20315c6d839a605d77682ca 162 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 10 146 28.478 T 29-03-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS06935 6e4fa670f20315c6d839a605d77682ca 162 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 19 140 4.1E-50 T 29-03-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS06935 6e4fa670f20315c6d839a605d77682ca 162 Pfam PF12838 4Fe-4S dicluster domain 62 116 6.6E-13 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain GBCGDNIH2_RS06935 6e4fa670f20315c6d839a605d77682ca 162 SUPERFAMILY SSF54862 36 146 1.09E-27 T 29-03-2018 GBCGDNIH2_RS06935 6e4fa670f20315c6d839a605d77682ca 162 Gene3D G3DSA:3.30.70.20 29 73 2.3E-6 T 29-03-2018 GBCGDNIH2_RS06935 6e4fa670f20315c6d839a605d77682ca 162 Gene3D G3DSA:3.30.70.20 106 155 2.7E-8 T 29-03-2018 GBCGDNIH2_RS06935 6e4fa670f20315c6d839a605d77682ca 162 Gene3D G3DSA:3.30.70.20 74 105 1.2E-14 T 29-03-2018 GBCGDNIH2_RS05110 cb5d79ff9c6ad5dc1bce8cf213e035ea 390 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 9 382 3.1E-133 T 29-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 GBCGDNIH2_RS05110 cb5d79ff9c6ad5dc1bce8cf213e035ea 390 SUPERFAMILY SSF69055 294 385 2.09E-30 T 29-03-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 GBCGDNIH2_RS05110 cb5d79ff9c6ad5dc1bce8cf213e035ea 390 Gene3D G3DSA:1.10.1740.10 305 388 5.7E-29 T 29-03-2018 GBCGDNIH2_RS05110 cb5d79ff9c6ad5dc1bce8cf213e035ea 390 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 10 384 44.403 T 29-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 GBCGDNIH2_RS05110 cb5d79ff9c6ad5dc1bce8cf213e035ea 390 PIRSF PIRSF006205 7 390 4.0E-142 T 29-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 GBCGDNIH2_RS05110 cb5d79ff9c6ad5dc1bce8cf213e035ea 390 Pfam PF13288 DXP reductoisomerase C-terminal domain 263 379 3.5E-40 T 29-03-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 GBCGDNIH2_RS05110 cb5d79ff9c6ad5dc1bce8cf213e035ea 390 SUPERFAMILY SSF51735 7 152 1.74E-42 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS05110 cb5d79ff9c6ad5dc1bce8cf213e035ea 390 SUPERFAMILY SSF55347 128 266 8.5E-57 T 29-03-2018 GBCGDNIH2_RS05110 cb5d79ff9c6ad5dc1bce8cf213e035ea 390 Gene3D G3DSA:3.40.50.720 7 152 1.7E-41 T 29-03-2018 GBCGDNIH2_RS05110 cb5d79ff9c6ad5dc1bce8cf213e035ea 390 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 10 134 2.1E-34 T 29-03-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 GBCGDNIH2_RS05110 cb5d79ff9c6ad5dc1bce8cf213e035ea 390 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 148 231 1.2E-37 T 29-03-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 GBCGDNIH2_RS09525 7aa2ca2696fbf287893e4f64be9ef21d 261 SUPERFAMILY SSF52540 46 242 8.91E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS09525 7aa2ca2696fbf287893e4f64be9ef21d 261 Pfam PF00005 ABC transporter 49 181 2.6E-17 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GBCGDNIH2_RS09525 7aa2ca2696fbf287893e4f64be9ef21d 261 SMART SM00382 58 230 1.7E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS09525 7aa2ca2696fbf287893e4f64be9ef21d 261 Gene3D G3DSA:3.40.50.300 2 256 2.2E-39 T 29-03-2018 GBCGDNIH2_RS06080 21adc3c6d761dd00d95eea98497b3ab0 460 Pfam PF16360 GTP-binding GTPase Middle Region 138 217 2.1E-29 T 29-03-2018 IPR032305 GTP-binding protein, middle domain GBCGDNIH2_RS06080 21adc3c6d761dd00d95eea98497b3ab0 460 PIRSF PIRSF006809 20 449 4.4E-135 T 29-03-2018 IPR016496 GTPase HflX GO:0005525 GBCGDNIH2_RS06080 21adc3c6d761dd00d95eea98497b3ab0 460 Hamap MF_00900 GTPase HflX [hflX]. 51 417 43.795 T 29-03-2018 IPR016496 GTPase HflX GO:0005525 GBCGDNIH2_RS06080 21adc3c6d761dd00d95eea98497b3ab0 460 Gene3D G3DSA:3.40.50.300 256 386 1.0E-13 T 29-03-2018 GBCGDNIH2_RS06080 21adc3c6d761dd00d95eea98497b3ab0 460 SUPERFAMILY SSF52540 223 391 9.3E-36 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS06080 21adc3c6d761dd00d95eea98497b3ab0 460 Pfam PF01926 50S ribosome-binding GTPase 225 324 1.2E-18 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 GBCGDNIH2_RS06080 21adc3c6d761dd00d95eea98497b3ab0 460 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 292 310 1.9E-7 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 GBCGDNIH2_RS06080 21adc3c6d761dd00d95eea98497b3ab0 460 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 225 245 1.9E-7 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 GBCGDNIH2_RS06080 21adc3c6d761dd00d95eea98497b3ab0 460 Gene3D G3DSA:3.40.50.300 191 255 8.0E-13 T 29-03-2018 GBCGDNIH2_RS06080 21adc3c6d761dd00d95eea98497b3ab0 460 Pfam PF13167 GTP-binding GTPase N-terminal 49 135 5.0E-23 T 29-03-2018 IPR025121 GTPase HflX, N-terminal GBCGDNIH2_RS06080 21adc3c6d761dd00d95eea98497b3ab0 460 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 46 387 1.1E-126 T 29-03-2018 IPR016496 GTPase HflX GO:0005525 GBCGDNIH2_RS03675 b3b63546386df29c7692c71ac7099beb 491 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 47 418 1.9E-60 T 29-03-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 GBCGDNIH2_RS03675 b3b63546386df29c7692c71ac7099beb 491 SUPERFAMILY SSF53383 15 480 9.11E-119 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase GBCGDNIH2_RS03675 b3b63546386df29c7692c71ac7099beb 491 Gene3D G3DSA:3.90.1150.10 368 482 4.2E-27 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 GBCGDNIH2_RS03675 b3b63546386df29c7692c71ac7099beb 491 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 85 104 9.5E-12 T 29-03-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 GBCGDNIH2_RS03675 b3b63546386df29c7692c71ac7099beb 491 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 59 78 9.5E-12 T 29-03-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 GBCGDNIH2_RS03675 b3b63546386df29c7692c71ac7099beb 491 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 19 38 9.5E-12 T 29-03-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 GBCGDNIH2_RS03675 b3b63546386df29c7692c71ac7099beb 491 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 123 142 9.5E-12 T 29-03-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 GBCGDNIH2_RS03675 b3b63546386df29c7692c71ac7099beb 491 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 353 368 9.5E-12 T 29-03-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 GBCGDNIH2_RS03675 b3b63546386df29c7692c71ac7099beb 491 Gene3D G3DSA:1.20.1340.10 14 92 5.3E-16 T 29-03-2018 GBCGDNIH2_RS03675 b3b63546386df29c7692c71ac7099beb 491 Gene3D G3DSA:3.40.640.10 95 367 3.0E-49 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GBCGDNIH2_RS12500 409975abf85812da3ada749fbc52e976 217 ProSitePatterns PS01081 TetR-type HTH domain signature. 53 84 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site GBCGDNIH2_RS12500 409975abf85812da3ada749fbc52e976 217 Pfam PF00440 Bacterial regulatory proteins, tetR family 41 87 1.4E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GBCGDNIH2_RS12500 409975abf85812da3ada749fbc52e976 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 54 3.8E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GBCGDNIH2_RS12500 409975abf85812da3ada749fbc52e976 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 62 85 3.8E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GBCGDNIH2_RS12500 409975abf85812da3ada749fbc52e976 217 Gene3D G3DSA:1.10.357.10 85 216 3.1E-13 T 29-03-2018 GBCGDNIH2_RS12500 409975abf85812da3ada749fbc52e976 217 Gene3D G3DSA:1.10.10.60 11 84 3.0E-19 T 29-03-2018 GBCGDNIH2_RS12500 409975abf85812da3ada749fbc52e976 217 SUPERFAMILY SSF46689 26 106 2.24E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 GBCGDNIH2_RS08980 d0b692759601c9d703492c818210a618 157 Gene3D G3DSA:3.40.1280.10 4 153 7.1E-41 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal GBCGDNIH2_RS08980 d0b692759601c9d703492c818210a618 157 PIRSF PIRSF004505 3 151 1.2E-38 T 29-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 GBCGDNIH2_RS08980 d0b692759601c9d703492c818210a618 157 Pfam PF02590 Predicted SPOUT methyltransferase 6 150 7.3E-39 T 29-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 GBCGDNIH2_RS08980 d0b692759601c9d703492c818210a618 157 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 3 151 24.276 T 29-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 GBCGDNIH2_RS08980 d0b692759601c9d703492c818210a618 157 SUPERFAMILY SSF75217 5 150 6.54E-38 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases GBCGDNIH2_RS06205 a522b23c8104455a73564f86b4f27fef 522 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 9 522 53.707 T 29-03-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 GBCGDNIH2_RS06205 a522b23c8104455a73564f86b4f27fef 522 Gene3D G3DSA:3.40.50.880 8 229 1.9E-50 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like GBCGDNIH2_RS06205 a522b23c8104455a73564f86b4f27fef 522 Pfam PF00958 GMP synthase C terminal domain 430 521 4.2E-43 T 29-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 GBCGDNIH2_RS06205 a522b23c8104455a73564f86b4f27fef 522 Pfam PF00117 Glutamine amidotransferase class-I 14 195 1.3E-39 T 29-03-2018 IPR017926 Glutamine amidotransferase GBCGDNIH2_RS06205 a522b23c8104455a73564f86b4f27fef 522 Pfam PF02540 NAD synthase 225 270 1.9E-5 T 29-03-2018 IPR022310 NAD/GMP synthase GBCGDNIH2_RS06205 a522b23c8104455a73564f86b4f27fef 522 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 213 522 3.3E-145 T 29-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 GBCGDNIH2_RS06205 a522b23c8104455a73564f86b4f27fef 522 SUPERFAMILY SSF54810 402 522 9.15E-51 T 29-03-2018 GBCGDNIH2_RS06205 a522b23c8104455a73564f86b4f27fef 522 SUPERFAMILY SSF52402 194 415 1.79E-58 T 29-03-2018 GBCGDNIH2_RS06205 a522b23c8104455a73564f86b4f27fef 522 PRINTS PR00096 Glutamine amidotransferase superfamily signature 174 187 4.8E-9 T 29-03-2018 GBCGDNIH2_RS06205 a522b23c8104455a73564f86b4f27fef 522 PRINTS PR00096 Glutamine amidotransferase superfamily signature 56 65 4.8E-9 T 29-03-2018 GBCGDNIH2_RS06205 a522b23c8104455a73564f86b4f27fef 522 PRINTS PR00096 Glutamine amidotransferase superfamily signature 83 94 4.8E-9 T 29-03-2018 GBCGDNIH2_RS06205 a522b23c8104455a73564f86b4f27fef 522 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 12 201 5.1E-71 T 29-03-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 GBCGDNIH2_RS06205 a522b23c8104455a73564f86b4f27fef 522 Gene3D G3DSA:3.30.300.10 398 522 1.5E-53 T 29-03-2018 GBCGDNIH2_RS06205 a522b23c8104455a73564f86b4f27fef 522 Gene3D G3DSA:3.40.50.620 230 390 1.9E-33 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GBCGDNIH2_RS06205 a522b23c8104455a73564f86b4f27fef 522 PRINTS PR00097 Anthranilate synthase component II signature 174 187 1.0E-7 T 29-03-2018 GBCGDNIH2_RS06205 a522b23c8104455a73564f86b4f27fef 522 PRINTS PR00097 Anthranilate synthase component II signature 83 94 1.0E-7 T 29-03-2018 GBCGDNIH2_RS06205 a522b23c8104455a73564f86b4f27fef 522 PRINTS PR00097 Anthranilate synthase component II signature 56 65 1.0E-7 T 29-03-2018 GBCGDNIH2_RS06205 a522b23c8104455a73564f86b4f27fef 522 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 53 67 1.1E-5 T 29-03-2018 GBCGDNIH2_RS06205 a522b23c8104455a73564f86b4f27fef 522 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 12 26 1.1E-5 T 29-03-2018 GBCGDNIH2_RS06205 a522b23c8104455a73564f86b4f27fef 522 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 83 99 1.1E-5 T 29-03-2018 GBCGDNIH2_RS06205 a522b23c8104455a73564f86b4f27fef 522 SUPERFAMILY SSF52317 4 234 1.7E-57 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like GBCGDNIH2_RS02785 2c12321852640073eef3782c171c895a 144 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 74 3.0E-15 T 29-03-2018 GBCGDNIH2_RS02785 2c12321852640073eef3782c171c895a 144 Pfam PF00298 Ribosomal protein L11, RNA binding domain 72 141 7.3E-21 T 29-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 GBCGDNIH2_RS02785 2c12321852640073eef3782c171c895a 144 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 143 30.19 T 29-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 GBCGDNIH2_RS02785 2c12321852640073eef3782c171c895a 144 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 142 2.1E-61 T 29-03-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS02785 2c12321852640073eef3782c171c895a 144 Gene3D G3DSA:3.30.1550.10 3 72 6.6E-36 T 29-03-2018 IPR020784 Ribosomal protein L11, N-terminal GBCGDNIH2_RS02785 2c12321852640073eef3782c171c895a 144 SUPERFAMILY SSF54747 3 73 4.58E-31 T 29-03-2018 IPR020784 Ribosomal protein L11, N-terminal GBCGDNIH2_RS02785 2c12321852640073eef3782c171c895a 144 Gene3D G3DSA:1.10.10.250 73 141 2.1E-18 T 29-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 GBCGDNIH2_RS02785 2c12321852640073eef3782c171c895a 144 SUPERFAMILY SSF46906 68 141 3.92E-22 T 29-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 GBCGDNIH2_RS02785 2c12321852640073eef3782c171c895a 144 ProSitePatterns PS00359 Ribosomal protein L11 signature. 128 143 - T 29-03-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02785 2c12321852640073eef3782c171c895a 144 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 67 2.0E-30 T 29-03-2018 IPR020784 Ribosomal protein L11, N-terminal GBCGDNIH2_RS02785 2c12321852640073eef3782c171c895a 144 SMART SM00649 9 142 6.5E-78 T 29-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 GBCGDNIH2_RS10020 f155a5f9bba7b3d36df40451bbee749b 183 TIGRFAM TIGR03865 PQQ_CXXCW: PQQ-dependent catabolism-associated CXXCW motif protein 11 176 1.0E-67 T 29-03-2018 IPR022376 PQQ-dependent catabolism-associated CXXCW motif GBCGDNIH2_RS10020 f155a5f9bba7b3d36df40451bbee749b 183 SUPERFAMILY SSF52821 46 179 1.83E-16 T 29-03-2018 IPR001763 Rhodanese-like domain GBCGDNIH2_RS10020 f155a5f9bba7b3d36df40451bbee749b 183 Gene3D G3DSA:3.40.250.10 37 182 1.6E-13 T 29-03-2018 IPR001763 Rhodanese-like domain GBCGDNIH2_RS00760 80b460ad35bd08b0c14db010a50ecea8 186 Gene3D G3DSA:3.30.1370.70 1 88 6.9E-33 T 29-03-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal GBCGDNIH2_RS00760 80b460ad35bd08b0c14db010a50ecea8 186 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 120 184 5.0E-29 T 29-03-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 GBCGDNIH2_RS00760 80b460ad35bd08b0c14db010a50ecea8 186 Pfam PF08712 Scaffold protein Nfu/NifU N terminal 3 88 5.7E-32 T 29-03-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal GBCGDNIH2_RS00760 80b460ad35bd08b0c14db010a50ecea8 186 SUPERFAMILY SSF117916 106 184 3.92E-28 T 29-03-2018 IPR034904 Fe-S cluster assembly domain GBCGDNIH2_RS00760 80b460ad35bd08b0c14db010a50ecea8 186 PIRSF PIRSF036773 1 186 1.1E-75 T 29-03-2018 IPR035433 NFU1-like GBCGDNIH2_RS00760 80b460ad35bd08b0c14db010a50ecea8 186 Gene3D G3DSA:3.30.300.130 107 186 1.3E-31 T 29-03-2018 IPR034904 Fe-S cluster assembly domain GBCGDNIH2_RS00760 80b460ad35bd08b0c14db010a50ecea8 186 Pfam PF01106 NifU-like domain 116 182 2.3E-28 T 29-03-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 GBCGDNIH2_RS00760 80b460ad35bd08b0c14db010a50ecea8 186 SMART SM00932 3 89 9.2E-52 T 29-03-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal GBCGDNIH2_RS00760 80b460ad35bd08b0c14db010a50ecea8 186 SUPERFAMILY SSF110836 1 91 1.15E-30 T 29-03-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal GBCGDNIH2_RS07915 d8f7bf1fc149e10452de913e5db9d931 525 Gene3D G3DSA:2.40.10.10 210 312 9.8E-39 T 29-03-2018 GBCGDNIH2_RS07915 d8f7bf1fc149e10452de913e5db9d931 525 Gene3D G3DSA:2.40.10.10 58 209 8.3E-34 T 29-03-2018 GBCGDNIH2_RS07915 d8f7bf1fc149e10452de913e5db9d931 525 Gene3D G3DSA:2.30.42.10 427 522 4.1E-15 T 29-03-2018 GBCGDNIH2_RS07915 d8f7bf1fc149e10452de913e5db9d931 525 SUPERFAMILY SSF50156 432 522 1.12E-14 T 29-03-2018 IPR001478 PDZ domain GO:0005515 GBCGDNIH2_RS07915 d8f7bf1fc149e10452de913e5db9d931 525 SMART SM00228 311 393 1.8E-11 T 29-03-2018 IPR001478 PDZ domain GO:0005515 GBCGDNIH2_RS07915 d8f7bf1fc149e10452de913e5db9d931 525 SMART SM00228 430 515 9.2E-10 T 29-03-2018 IPR001478 PDZ domain GO:0005515 GBCGDNIH2_RS07915 d8f7bf1fc149e10452de913e5db9d931 525 SUPERFAMILY SSF50494 60 303 8.48E-65 T 29-03-2018 IPR009003 Peptidase S1, PA clan GBCGDNIH2_RS07915 d8f7bf1fc149e10452de913e5db9d931 525 PRINTS PR00834 HtrA/DegQ protease family signature 166 186 4.0E-52 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 GBCGDNIH2_RS07915 d8f7bf1fc149e10452de913e5db9d931 525 PRINTS PR00834 HtrA/DegQ protease family signature 351 363 4.0E-52 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 GBCGDNIH2_RS07915 d8f7bf1fc149e10452de913e5db9d931 525 PRINTS PR00834 HtrA/DegQ protease family signature 243 260 4.0E-52 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 GBCGDNIH2_RS07915 d8f7bf1fc149e10452de913e5db9d931 525 PRINTS PR00834 HtrA/DegQ protease family signature 145 157 4.0E-52 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 GBCGDNIH2_RS07915 d8f7bf1fc149e10452de913e5db9d931 525 PRINTS PR00834 HtrA/DegQ protease family signature 209 233 4.0E-52 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 GBCGDNIH2_RS07915 d8f7bf1fc149e10452de913e5db9d931 525 PRINTS PR00834 HtrA/DegQ protease family signature 265 282 4.0E-52 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 GBCGDNIH2_RS07915 d8f7bf1fc149e10452de913e5db9d931 525 Pfam PF13365 Trypsin-like peptidase domain 135 272 3.6E-34 T 29-03-2018 GBCGDNIH2_RS07915 d8f7bf1fc149e10452de913e5db9d931 525 Gene3D G3DSA:2.30.42.10 313 416 1.5E-27 T 29-03-2018 GBCGDNIH2_RS07915 d8f7bf1fc149e10452de913e5db9d931 525 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 62 513 6.5E-152 T 29-03-2018 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 GBCGDNIH2_RS07915 d8f7bf1fc149e10452de913e5db9d931 525 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 443 511 2.3E-8 T 29-03-2018 IPR001478 PDZ domain GO:0005515 GBCGDNIH2_RS07915 d8f7bf1fc149e10452de913e5db9d931 525 Pfam PF13180 PDZ domain 311 400 1.2E-15 T 29-03-2018 IPR001478 PDZ domain GO:0005515 GBCGDNIH2_RS07915 d8f7bf1fc149e10452de913e5db9d931 525 SUPERFAMILY SSF50156 269 394 2.5E-25 T 29-03-2018 IPR001478 PDZ domain GO:0005515 GBCGDNIH2_RS07360 79ed1a27cbcdb4efd7dc0d21662efe0b 167 TIGRFAM TIGR02548 casB_cse2: CRISPR type I-E/ECOLI-associated protein CasB/Cse2 16 154 3.7E-15 T 29-03-2018 IPR013382 CRISPR-associated protein Cse2 GBCGDNIH2_RS07360 79ed1a27cbcdb4efd7dc0d21662efe0b 167 Pfam PF09485 CRISPR-associated protein Cse2 (CRISPR_cse2) 34 154 2.4E-10 T 29-03-2018 IPR013382 CRISPR-associated protein Cse2 GBCGDNIH2_RS07920 568aae1811e40017953bad92a6d399a0 379 Hamap MF_02040 Iron-sulfur cluster carrier protein. 116 363 37.027 T 29-03-2018 IPR019591 Mrp/NBP35 ATP-binding protein GBCGDNIH2_RS07920 568aae1811e40017953bad92a6d399a0 379 Gene3D G3DSA:3.40.50.300 123 376 8.9E-65 T 29-03-2018 GBCGDNIH2_RS07920 568aae1811e40017953bad92a6d399a0 379 Pfam PF01883 Iron-sulfur cluster assembly protein 15 84 2.8E-12 T 29-03-2018 IPR002744 MIP18 family-like GBCGDNIH2_RS07920 568aae1811e40017953bad92a6d399a0 379 SUPERFAMILY SSF117916 14 95 9.81E-14 T 29-03-2018 IPR034904 Fe-S cluster assembly domain GBCGDNIH2_RS07920 568aae1811e40017953bad92a6d399a0 379 SUPERFAMILY SSF52540 124 368 6.96E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS07920 568aae1811e40017953bad92a6d399a0 379 Gene3D G3DSA:3.30.300.130 11 101 4.2E-9 T 29-03-2018 IPR034904 Fe-S cluster assembly domain GBCGDNIH2_RS07920 568aae1811e40017953bad92a6d399a0 379 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 121 362 1.3E-100 T 29-03-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 GBCGDNIH2_RS07920 568aae1811e40017953bad92a6d399a0 379 ProSitePatterns PS01215 Mrp family signature. 226 242 - T 29-03-2018 IPR000808 Mrp, conserved site GO:0005524 GBCGDNIH2_RS01245 fa0797561bac1721916ccb57a854190d 331 Pfam PF04055 Radical SAM superfamily 35 166 1.3E-18 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 GBCGDNIH2_RS01245 fa0797561bac1721916ccb57a854190d 331 SMART SM00729 31 221 1.8E-5 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 GBCGDNIH2_RS01245 fa0797561bac1721916ccb57a854190d 331 Gene3D G3DSA:3.20.20.70 21 299 8.8E-35 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS01245 fa0797561bac1721916ccb57a854190d 331 SUPERFAMILY SSF102114 28 290 4.71E-39 T 29-03-2018 GBCGDNIH2_RS01245 fa0797561bac1721916ccb57a854190d 331 Pfam PF13353 4Fe-4S single cluster domain 35 116 1.3E-6 T 29-03-2018 GBCGDNIH2_RS07265 9bd24ab2d27a0ca06820b7e27c4fb236 75 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 69 2.5E-33 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS07265 9bd24ab2d27a0ca06820b7e27c4fb236 75 PRINTS PR01249 Ribosomal protein L31 signature 2 19 1.9E-14 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS07265 9bd24ab2d27a0ca06820b7e27c4fb236 75 PRINTS PR01249 Ribosomal protein L31 signature 34 49 1.9E-14 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS07265 9bd24ab2d27a0ca06820b7e27c4fb236 75 PRINTS PR01249 Ribosomal protein L31 signature 49 67 1.9E-14 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS07265 9bd24ab2d27a0ca06820b7e27c4fb236 75 Pfam PF01197 Ribosomal protein L31 1 68 8.9E-27 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS07265 9bd24ab2d27a0ca06820b7e27c4fb236 75 ProSitePatterns PS01143 Ribosomal protein L31 signature. 38 59 - T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS07265 9bd24ab2d27a0ca06820b7e27c4fb236 75 SUPERFAMILY SSF143800 1 70 7.85E-23 T 29-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS07265 9bd24ab2d27a0ca06820b7e27c4fb236 75 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 71 26.208 T 29-03-2018 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS01225 e0e14da5d745c0f20e687219c90d49ce 582 Pfam PF00501 AMP-binding enzyme 49 469 5.4E-65 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 GBCGDNIH2_RS01225 e0e14da5d745c0f20e687219c90d49ce 582 Gene3D G3DSA:2.30.38.10 372 461 1.3E-18 T 29-03-2018 GBCGDNIH2_RS01225 e0e14da5d745c0f20e687219c90d49ce 582 Gene3D G3DSA:3.40.50.980 20 187 7.4E-22 T 29-03-2018 GBCGDNIH2_RS01225 e0e14da5d745c0f20e687219c90d49ce 582 Gene3D G3DSA:3.40.50.980 188 359 5.7E-30 T 29-03-2018 GBCGDNIH2_RS01225 e0e14da5d745c0f20e687219c90d49ce 582 SUPERFAMILY SSF56801 385 570 1.03E-92 T 29-03-2018 GBCGDNIH2_RS01225 e0e14da5d745c0f20e687219c90d49ce 582 SUPERFAMILY SSF56801 23 357 1.03E-92 T 29-03-2018 GBCGDNIH2_RS01225 e0e14da5d745c0f20e687219c90d49ce 582 Gene3D G3DSA:3.30.300.30 462 569 2.1E-15 T 29-03-2018 GBCGDNIH2_RS01970 4aa0e24db42cd0f3577e136c0d7dda48 545 Gene3D G3DSA:2.40.10.10 92 221 1.4E-36 T 29-03-2018 GBCGDNIH2_RS01970 4aa0e24db42cd0f3577e136c0d7dda48 545 SMART SM00228 328 415 2.9E-7 T 29-03-2018 IPR001478 PDZ domain GO:0005515 GBCGDNIH2_RS01970 4aa0e24db42cd0f3577e136c0d7dda48 545 SMART SM00228 446 529 4.0E-14 T 29-03-2018 IPR001478 PDZ domain GO:0005515 GBCGDNIH2_RS01970 4aa0e24db42cd0f3577e136c0d7dda48 545 SUPERFAMILY SSF50156 355 465 1.84E-19 T 29-03-2018 IPR001478 PDZ domain GO:0005515 GBCGDNIH2_RS01970 4aa0e24db42cd0f3577e136c0d7dda48 545 Gene3D G3DSA:2.30.42.10 323 437 4.8E-21 T 29-03-2018 GBCGDNIH2_RS01970 4aa0e24db42cd0f3577e136c0d7dda48 545 Gene3D G3DSA:2.30.42.10 442 545 8.1E-23 T 29-03-2018 GBCGDNIH2_RS01970 4aa0e24db42cd0f3577e136c0d7dda48 545 PRINTS PR00834 HtrA/DegQ protease family signature 226 250 1.9E-51 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 GBCGDNIH2_RS01970 4aa0e24db42cd0f3577e136c0d7dda48 545 PRINTS PR00834 HtrA/DegQ protease family signature 260 277 1.9E-51 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 GBCGDNIH2_RS01970 4aa0e24db42cd0f3577e136c0d7dda48 545 PRINTS PR00834 HtrA/DegQ protease family signature 282 299 1.9E-51 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 GBCGDNIH2_RS01970 4aa0e24db42cd0f3577e136c0d7dda48 545 PRINTS PR00834 HtrA/DegQ protease family signature 164 176 1.9E-51 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 GBCGDNIH2_RS01970 4aa0e24db42cd0f3577e136c0d7dda48 545 PRINTS PR00834 HtrA/DegQ protease family signature 373 385 1.9E-51 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 GBCGDNIH2_RS01970 4aa0e24db42cd0f3577e136c0d7dda48 545 PRINTS PR00834 HtrA/DegQ protease family signature 185 205 1.9E-51 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 GBCGDNIH2_RS01970 4aa0e24db42cd0f3577e136c0d7dda48 545 Pfam PF13180 PDZ domain 328 423 1.8E-14 T 29-03-2018 IPR001478 PDZ domain GO:0005515 GBCGDNIH2_RS01970 4aa0e24db42cd0f3577e136c0d7dda48 545 Pfam PF13180 PDZ domain 446 531 1.2E-12 T 29-03-2018 IPR001478 PDZ domain GO:0005515 GBCGDNIH2_RS01970 4aa0e24db42cd0f3577e136c0d7dda48 545 SUPERFAMILY SSF50494 94 319 2.82E-64 T 29-03-2018 IPR009003 Peptidase S1, PA clan GBCGDNIH2_RS01970 4aa0e24db42cd0f3577e136c0d7dda48 545 Pfam PF13365 Trypsin-like peptidase domain 155 289 6.0E-36 T 29-03-2018 GBCGDNIH2_RS01970 4aa0e24db42cd0f3577e136c0d7dda48 545 SUPERFAMILY SSF50156 446 536 6.31E-19 T 29-03-2018 IPR001478 PDZ domain GO:0005515 GBCGDNIH2_RS01970 4aa0e24db42cd0f3577e136c0d7dda48 545 Gene3D G3DSA:2.40.10.10 222 322 4.3E-37 T 29-03-2018 GBCGDNIH2_RS03190 5183e85626c72227532f184def922b57 261 SMART SM00852 11 171 2.5E-33 T 29-03-2018 IPR001453 MoaB/Mog domain GBCGDNIH2_RS03190 5183e85626c72227532f184def922b57 261 Pfam PF00994 Probable molybdopterin binding domain 12 169 7.1E-30 T 29-03-2018 IPR001453 MoaB/Mog domain GBCGDNIH2_RS03190 5183e85626c72227532f184def922b57 261 Gene3D G3DSA:3.40.980.10 7 171 1.1E-42 T 29-03-2018 IPR001453 MoaB/Mog domain GBCGDNIH2_RS03190 5183e85626c72227532f184def922b57 261 SUPERFAMILY SSF53218 10 202 1.83E-38 T 29-03-2018 IPR001453 MoaB/Mog domain GBCGDNIH2_RS00740 d07184631f2a66c0f8ce3f3230e12897 226 Pfam PF00072 Response regulator receiver domain 3 113 2.1E-23 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GBCGDNIH2_RS00740 d07184631f2a66c0f8ce3f3230e12897 226 SUPERFAMILY SSF52172 1 179 1.81E-34 T 29-03-2018 IPR011006 CheY-like superfamily GBCGDNIH2_RS00740 d07184631f2a66c0f8ce3f3230e12897 226 SMART SM00862 147 222 3.7E-28 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 GBCGDNIH2_RS00740 d07184631f2a66c0f8ce3f3230e12897 226 Gene3D G3DSA:3.40.50.2300 1 123 8.4E-30 T 29-03-2018 GBCGDNIH2_RS00740 d07184631f2a66c0f8ce3f3230e12897 226 Gene3D G3DSA:1.10.10.10 124 226 4.6E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS00740 d07184631f2a66c0f8ce3f3230e12897 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 222 2.0E-27 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 GBCGDNIH2_RS00740 d07184631f2a66c0f8ce3f3230e12897 226 SMART SM00448 1 113 5.0E-36 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GBCGDNIH2_RS09830 7baff0aeba04959468d67f0e99408fa8 204 Pfam PF02622 Uncharacterized ACR, COG1678 33 189 1.6E-44 T 29-03-2018 IPR003774 Protein of unknown function UPF0301 GBCGDNIH2_RS09830 7baff0aeba04959468d67f0e99408fa8 204 SUPERFAMILY SSF143456 23 204 3.14E-60 T 29-03-2018 GBCGDNIH2_RS09830 7baff0aeba04959468d67f0e99408fa8 204 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 22 204 35.86 T 29-03-2018 IPR003774 Protein of unknown function UPF0301 GBCGDNIH2_RS09830 7baff0aeba04959468d67f0e99408fa8 204 Gene3D G3DSA:3.40.1740.10 9 110 6.7E-25 T 29-03-2018 GBCGDNIH2_RS09830 7baff0aeba04959468d67f0e99408fa8 204 Gene3D G3DSA:3.40.1740.10 132 196 1.9E-8 T 29-03-2018 GBCGDNIH2_RS05670 e44f33d1e3c66d5864d4926386419dce 340 Pfam PF02371 Transposase IS116/IS110/IS902 family 211 291 1.9E-24 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 GBCGDNIH2_RS05670 e44f33d1e3c66d5864d4926386419dce 340 Pfam PF01548 Transposase 5 149 5.4E-13 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 GBCGDNIH2_RS05670 e44f33d1e3c66d5864d4926386419dce 340 Gene3D G3DSA:1.10.150.20 81 240 0.002 T 29-03-2018 GBCGDNIH2_RS02235 33772a23ad41b686c0961783af2c56a7 542 Gene3D G3DSA:3.40.1390.10 53 155 4.3E-20 T 29-03-2018 GBCGDNIH2_RS02235 33772a23ad41b686c0961783af2c56a7 542 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 53 537 28.76 T 29-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 GBCGDNIH2_RS02235 33772a23ad41b686c0961783af2c56a7 542 Pfam PF08245 Mur ligase middle domain 164 368 1.2E-36 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 GBCGDNIH2_RS02235 33772a23ad41b686c0961783af2c56a7 542 Pfam PF02875 Mur ligase family, glutamate ligase domain 387 472 5.9E-19 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 GBCGDNIH2_RS02235 33772a23ad41b686c0961783af2c56a7 542 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 77 536 1.6E-125 T 29-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 GBCGDNIH2_RS02235 33772a23ad41b686c0961783af2c56a7 542 Pfam PF01225 Mur ligase family, catalytic domain 77 125 9.0E-10 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 GBCGDNIH2_RS02235 33772a23ad41b686c0961783af2c56a7 542 SUPERFAMILY SSF53244 387 537 9.68E-45 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 GBCGDNIH2_RS02235 33772a23ad41b686c0961783af2c56a7 542 Gene3D G3DSA:3.40.1190.10 156 391 1.3E-41 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 GBCGDNIH2_RS02235 33772a23ad41b686c0961783af2c56a7 542 Gene3D G3DSA:3.90.190.20 396 542 8.5E-48 T 29-03-2018 GBCGDNIH2_RS02235 33772a23ad41b686c0961783af2c56a7 542 SUPERFAMILY SSF63418 68 153 7.32E-19 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 GBCGDNIH2_RS02235 33772a23ad41b686c0961783af2c56a7 542 SUPERFAMILY SSF53623 157 374 5.84E-58 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 GBCGDNIH2_RS05880 55d5e8d9097a46e5b15c99864c82329a 362 TIGRFAM TIGR03822 AblA_like_2: lysine-2,3-aminomutase-related protein 27 341 4.6E-160 T 29-03-2018 IPR022447 Lysine-2,3-aminomutase-related GBCGDNIH2_RS05880 55d5e8d9097a46e5b15c99864c82329a 362 Pfam PF04055 Radical SAM superfamily 117 263 2.2E-9 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 GBCGDNIH2_RS05880 55d5e8d9097a46e5b15c99864c82329a 362 Gene3D G3DSA:3.20.20.70 102 333 1.3E-21 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS05880 55d5e8d9097a46e5b15c99864c82329a 362 PIRSF PIRSF004911 9 357 1.7E-111 T 29-03-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase GBCGDNIH2_RS05880 55d5e8d9097a46e5b15c99864c82329a 362 TIGRFAM TIGR00238 TIGR00238: KamA family protein 28 328 1.2E-73 T 29-03-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase GBCGDNIH2_RS05880 55d5e8d9097a46e5b15c99864c82329a 362 Pfam PF13353 4Fe-4S single cluster domain 120 171 5.8E-5 T 29-03-2018 GBCGDNIH2_RS05880 55d5e8d9097a46e5b15c99864c82329a 362 Pfam PF12544 Lysine-2,3-aminomutase 308 345 4.5E-9 T 29-03-2018 IPR025895 Lysine-2,3-aminomutase, C-terminal domain GBCGDNIH2_RS05880 55d5e8d9097a46e5b15c99864c82329a 362 SUPERFAMILY SSF102114 100 341 2.22E-31 T 29-03-2018 GBCGDNIH2_RS00975 c100ea7996926edfc9bb9b83b093b75e 757 Gene3D G3DSA:3.90.70.10 36 156 8.7E-8 T 29-03-2018 GBCGDNIH2_RS00975 c100ea7996926edfc9bb9b83b093b75e 757 SMART SM00382 526 723 1.9E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS00975 c100ea7996926edfc9bb9b83b093b75e 757 ProSitePatterns PS00211 ABC transporters family signature. 638 652 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GBCGDNIH2_RS00975 c100ea7996926edfc9bb9b83b093b75e 757 SUPERFAMILY SSF90123 165 484 9.94E-54 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 GBCGDNIH2_RS00975 c100ea7996926edfc9bb9b83b093b75e 757 Pfam PF00664 ABC transporter transmembrane region 186 447 1.7E-30 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 GBCGDNIH2_RS00975 c100ea7996926edfc9bb9b83b093b75e 757 Gene3D G3DSA:1.20.1560.10 157 486 1.6E-42 T 29-03-2018 GBCGDNIH2_RS00975 c100ea7996926edfc9bb9b83b093b75e 757 SUPERFAMILY SSF52540 494 736 1.64E-81 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS00975 c100ea7996926edfc9bb9b83b093b75e 757 Gene3D G3DSA:3.40.50.300 487 742 2.6E-70 T 29-03-2018 GBCGDNIH2_RS00975 c100ea7996926edfc9bb9b83b093b75e 757 Pfam PF00005 ABC transporter 519 666 1.7E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GBCGDNIH2_RS08635 85847debfeb4c7b2b8822229fbb99b53 954 Pfam PF07584 Aerotolerance regulator N-terminal 1 75 2.2E-18 T 29-03-2018 IPR024163 Aerotolerance regulator, N-terminal GBCGDNIH2_RS08635 85847debfeb4c7b2b8822229fbb99b53 954 Gene3D G3DSA:3.40.50.880 317 555 3.4E-19 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like GBCGDNIH2_RS08635 85847debfeb4c7b2b8822229fbb99b53 954 Pfam PF13709 Domain of unknown function (DUF4159) 727 934 2.5E-49 T 29-03-2018 IPR025297 Domain of unknown function DUF4159 GBCGDNIH2_RS08635 85847debfeb4c7b2b8822229fbb99b53 954 SUPERFAMILY SSF52317 360 453 1.99E-8 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like GBCGDNIH2_RS08635 85847debfeb4c7b2b8822229fbb99b53 954 SUPERFAMILY SSF52317 486 537 1.99E-8 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like GBCGDNIH2_RS08635 85847debfeb4c7b2b8822229fbb99b53 954 Gene3D G3DSA:3.40.50.880 756 936 1.3E-9 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like GBCGDNIH2_RS08635 85847debfeb4c7b2b8822229fbb99b53 954 TIGRFAM TIGR02226 two_anch: N-terminal double-transmembrane domain 1 78 4.1E-20 T 29-03-2018 IPR011933 Double transmembrane domain GBCGDNIH2_RS09195 65266f8e683ce708413f0df758351746 440 SUPERFAMILY SSF53335 194 437 1.67E-54 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GBCGDNIH2_RS09195 65266f8e683ce708413f0df758351746 440 Pfam PF01189 16S rRNA methyltransferase RsmB/F 234 437 1.2E-45 T 29-03-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 GBCGDNIH2_RS09195 65266f8e683ce708413f0df758351746 440 Gene3D G3DSA:3.40.50.150 224 440 1.4E-50 T 29-03-2018 GBCGDNIH2_RS09195 65266f8e683ce708413f0df758351746 440 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 422 439 1.4E-24 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 GBCGDNIH2_RS09195 65266f8e683ce708413f0df758351746 440 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 215 229 1.4E-24 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 GBCGDNIH2_RS09195 65266f8e683ce708413f0df758351746 440 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 307 319 1.4E-24 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 GBCGDNIH2_RS09195 65266f8e683ce708413f0df758351746 440 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 244 254 1.4E-24 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 GBCGDNIH2_RS09195 65266f8e683ce708413f0df758351746 440 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 357 373 1.4E-24 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 GBCGDNIH2_RS09195 65266f8e683ce708413f0df758351746 440 SUPERFAMILY SSF48013 23 159 5.56E-27 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 GBCGDNIH2_RS09195 65266f8e683ce708413f0df758351746 440 Pfam PF01029 NusB family 22 138 1.6E-21 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 GBCGDNIH2_RS09195 65266f8e683ce708413f0df758351746 440 Gene3D G3DSA:1.10.940.10 19 153 9.0E-26 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 GBCGDNIH2_RS11700 4fb6ecdc40c2d6d7e397640805f275e6 531 PRINTS PR01165 Cytochrome c oxidase subunit I signature 172 190 1.1E-145 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS11700 4fb6ecdc40c2d6d7e397640805f275e6 531 PRINTS PR01165 Cytochrome c oxidase subunit I signature 99 123 1.1E-145 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS11700 4fb6ecdc40c2d6d7e397640805f275e6 531 PRINTS PR01165 Cytochrome c oxidase subunit I signature 298 313 1.1E-145 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS11700 4fb6ecdc40c2d6d7e397640805f275e6 531 PRINTS PR01165 Cytochrome c oxidase subunit I signature 385 404 1.1E-145 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS11700 4fb6ecdc40c2d6d7e397640805f275e6 531 PRINTS PR01165 Cytochrome c oxidase subunit I signature 201 220 1.1E-145 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS11700 4fb6ecdc40c2d6d7e397640805f275e6 531 PRINTS PR01165 Cytochrome c oxidase subunit I signature 252 273 1.1E-145 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS11700 4fb6ecdc40c2d6d7e397640805f275e6 531 PRINTS PR01165 Cytochrome c oxidase subunit I signature 435 456 1.1E-145 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS11700 4fb6ecdc40c2d6d7e397640805f275e6 531 PRINTS PR01165 Cytochrome c oxidase subunit I signature 140 152 1.1E-145 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS11700 4fb6ecdc40c2d6d7e397640805f275e6 531 PRINTS PR01165 Cytochrome c oxidase subunit I signature 71 94 1.1E-145 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS11700 4fb6ecdc40c2d6d7e397640805f275e6 531 PRINTS PR01165 Cytochrome c oxidase subunit I signature 322 343 1.1E-145 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS11700 4fb6ecdc40c2d6d7e397640805f275e6 531 PRINTS PR01165 Cytochrome c oxidase subunit I signature 23 48 1.1E-145 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS11700 4fb6ecdc40c2d6d7e397640805f275e6 531 PRINTS PR01165 Cytochrome c oxidase subunit I signature 357 375 1.1E-145 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS11700 4fb6ecdc40c2d6d7e397640805f275e6 531 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 32 477 2.2E-154 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS11700 4fb6ecdc40c2d6d7e397640805f275e6 531 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 254 308 - T 29-03-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS11700 4fb6ecdc40c2d6d7e397640805f275e6 531 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 24 530 1.5E-215 T 29-03-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 GBCGDNIH2_RS11700 4fb6ecdc40c2d6d7e397640805f275e6 531 Gene3D G3DSA:1.20.210.10 19 531 9.7E-251 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS11700 4fb6ecdc40c2d6d7e397640805f275e6 531 SUPERFAMILY SSF81442 21 530 1.19E-213 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS07215 cfc77d4bf18d0648a63cfcf412411500 272 SUPERFAMILY SSF51294 74 201 1.96E-13 T 29-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 GBCGDNIH2_RS07215 cfc77d4bf18d0648a63cfcf412411500 272 Pfam PF13403 Hint domain 74 202 4.4E-45 T 29-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 GBCGDNIH2_RS07215 cfc77d4bf18d0648a63cfcf412411500 272 Gene3D G3DSA:2.170.16.10 73 269 3.9E-16 T 29-03-2018 GBCGDNIH2_RS03605 48a9e55991d654b82479d2771b91bb6b 222 SUPERFAMILY SSF52833 1 103 5.99E-27 T 29-03-2018 IPR012336 Thioredoxin-like fold GBCGDNIH2_RS03605 48a9e55991d654b82479d2771b91bb6b 222 Pfam PF13417 Glutathione S-transferase, N-terminal domain 4 77 2.1E-22 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 GBCGDNIH2_RS03605 48a9e55991d654b82479d2771b91bb6b 222 Gene3D G3DSA:1.20.1050.10 98 212 1.2E-19 T 29-03-2018 GBCGDNIH2_RS03605 48a9e55991d654b82479d2771b91bb6b 222 SUPERFAMILY SSF47616 70 216 7.53E-26 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like GBCGDNIH2_RS03605 48a9e55991d654b82479d2771b91bb6b 222 Pfam PF00043 Glutathione S-transferase, C-terminal domain 143 198 8.6E-6 T 29-03-2018 IPR004046 Glutathione S-transferase, C-terminal GBCGDNIH2_RS03605 48a9e55991d654b82479d2771b91bb6b 222 Gene3D G3DSA:3.40.30.10 2 97 1.2E-28 T 29-03-2018 GBCGDNIH2_RS09860 d6f731590b597c2d2d17acf3c4edba60 428 SUPERFAMILY SSF53335 30 158 2.07E-12 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GBCGDNIH2_RS09860 d6f731590b597c2d2d17acf3c4edba60 428 Gene3D G3DSA:3.40.50.150 84 291 1.8E-7 T 29-03-2018 GBCGDNIH2_RS02930 cbeb23bb74510d8f35e0d4e4870640f8 160 SUPERFAMILY SSF52080 4 151 2.62E-39 T 29-03-2018 IPR021131 Ribosomal protein L18e/L15P GBCGDNIH2_RS02930 cbeb23bb74510d8f35e0d4e4870640f8 160 ProSitePatterns PS00475 Ribosomal protein L15 signature. 116 146 - T 29-03-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02930 cbeb23bb74510d8f35e0d4e4870640f8 160 Gene3D G3DSA:3.100.10.10 41 160 3.5E-28 T 29-03-2018 GBCGDNIH2_RS02930 cbeb23bb74510d8f35e0d4e4870640f8 160 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 27 150 8.2E-34 T 29-03-2018 IPR021131 Ribosomal protein L18e/L15P GBCGDNIH2_RS02930 cbeb23bb74510d8f35e0d4e4870640f8 160 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 149 1.4E-44 T 29-03-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS02930 cbeb23bb74510d8f35e0d4e4870640f8 160 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 152 19.901 T 29-03-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 GBCGDNIH2_RS07535 cc049a5a5f1574b5d12b7e102b119a58 221 Pfam PF14366 Domain of unknown function (DUF4410) 43 183 9.1E-43 T 29-03-2018 IPR025522 Protein of unknown function DUF4410 GBCGDNIH2_RS01920 04fb903cb6545710217d1706b5754cc9 746 Gene3D G3DSA:2.170.130.10 48 179 1.4E-9 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 GBCGDNIH2_RS01920 04fb903cb6545710217d1706b5754cc9 746 Gene3D G3DSA:2.40.170.20 191 746 3.2E-46 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 GBCGDNIH2_RS01920 04fb903cb6545710217d1706b5754cc9 746 Pfam PF00593 TonB dependent receptor 245 745 2.8E-24 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 GBCGDNIH2_RS01920 04fb903cb6545710217d1706b5754cc9 746 Pfam PF07715 TonB-dependent Receptor Plug Domain 72 174 7.5E-11 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 GBCGDNIH2_RS01920 04fb903cb6545710217d1706b5754cc9 746 SUPERFAMILY SSF56935 473 746 8.42E-76 T 29-03-2018 GBCGDNIH2_RS01920 04fb903cb6545710217d1706b5754cc9 746 SUPERFAMILY SSF56935 61 430 8.42E-76 T 29-03-2018 GBCGDNIH2_RS11070 2af6164c5b8b4449ce6d8bc6b821da3f 876 SMART SM00843 806 871 4.2E-37 T 29-03-2018 IPR018541 FtsK gamma domain GBCGDNIH2_RS11070 2af6164c5b8b4449ce6d8bc6b821da3f 876 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 26 192 2.1E-28 T 29-03-2018 IPR025199 DNA translocase FtsK, 4TM region GBCGDNIH2_RS11070 2af6164c5b8b4449ce6d8bc6b821da3f 876 Gene3D G3DSA:3.40.50.300 269 749 3.9E-54 T 29-03-2018 GBCGDNIH2_RS11070 2af6164c5b8b4449ce6d8bc6b821da3f 876 Pfam PF01580 FtsK/SpoIIIE family 484 703 1.3E-63 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 GBCGDNIH2_RS11070 2af6164c5b8b4449ce6d8bc6b821da3f 876 SMART SM00382 519 724 6.7E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS11070 2af6164c5b8b4449ce6d8bc6b821da3f 876 SUPERFAMILY SSF52540 464 774 1.45E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS11070 2af6164c5b8b4449ce6d8bc6b821da3f 876 Gene3D G3DSA:1.10.10.10 809 862 4.5E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS11070 2af6164c5b8b4449ce6d8bc6b821da3f 876 SUPERFAMILY SSF46785 807 870 6.8E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS11070 2af6164c5b8b4449ce6d8bc6b821da3f 876 Pfam PF09397 Ftsk gamma domain 811 868 8.5E-27 T 29-03-2018 IPR018541 FtsK gamma domain GBCGDNIH2_RS05075 6d5bd7a0f9844497e7790adf09ce5d76 220 Gene3D G3DSA:3.40.50.150 14 213 1.8E-22 T 29-03-2018 GBCGDNIH2_RS05075 6d5bd7a0f9844497e7790adf09ce5d76 220 SUPERFAMILY SSF53335 9 182 1.44E-30 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GBCGDNIH2_RS05075 6d5bd7a0f9844497e7790adf09ce5d76 220 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 19 176 1.0E-24 T 29-03-2018 GBCGDNIH2_RS01430 19f3549ac19e156ef77f6b393a246364 355 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 222 238 - T 29-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 GBCGDNIH2_RS01430 19f3549ac19e156ef77f6b393a246364 355 SUPERFAMILY SSF75620 9 342 7.72E-129 T 29-03-2018 GBCGDNIH2_RS01430 19f3549ac19e156ef77f6b393a246364 355 Gene3D G3DSA:3.30.160.20 203 286 2.6E-34 T 29-03-2018 GBCGDNIH2_RS01430 19f3549ac19e156ef77f6b393a246364 355 Pfam PF03462 PCRF domain 8 197 4.3E-59 T 29-03-2018 IPR005139 Peptide chain release factor GO:0006415 GBCGDNIH2_RS01430 19f3549ac19e156ef77f6b393a246364 355 Hamap MF_00094 Peptide chain release factor 2 [prfB]. 1 343 38.831 T 29-03-2018 IPR020853 Peptide chain release factor 2, bacterial GO:0005737|GO:0006415|GO:0016149 GBCGDNIH2_RS01430 19f3549ac19e156ef77f6b393a246364 355 Pfam PF00472 RF-1 domain 205 315 5.3E-42 T 29-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 GBCGDNIH2_RS01430 19f3549ac19e156ef77f6b393a246364 355 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 2 342 2.4E-152 T 29-03-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 GBCGDNIH2_RS01430 19f3549ac19e156ef77f6b393a246364 355 Gene3D G3DSA:1.20.58.410 1 93 2.7E-20 T 29-03-2018 GBCGDNIH2_RS01430 19f3549ac19e156ef77f6b393a246364 355 SMART SM00937 62 172 1.7E-52 T 29-03-2018 IPR005139 Peptide chain release factor GO:0006415 GBCGDNIH2_RS06920 82f457748b95b19c34374a03373b6d98 644 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 274 296 1.3E-10 T 29-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 GBCGDNIH2_RS06920 82f457748b95b19c34374a03373b6d98 644 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 427 449 1.3E-10 T 29-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 GBCGDNIH2_RS06920 82f457748b95b19c34374a03373b6d98 644 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 85 105 1.3E-10 T 29-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 GBCGDNIH2_RS06920 82f457748b95b19c34374a03373b6d98 644 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 67 123 2.7E-21 T 29-03-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS06920 82f457748b95b19c34374a03373b6d98 644 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 112 132 2.3E-62 T 29-03-2018 GBCGDNIH2_RS06920 82f457748b95b19c34374a03373b6d98 644 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 428 447 2.3E-62 T 29-03-2018 GBCGDNIH2_RS06920 82f457748b95b19c34374a03373b6d98 644 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 159 180 2.3E-62 T 29-03-2018 GBCGDNIH2_RS06920 82f457748b95b19c34374a03373b6d98 644 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 256 282 2.3E-62 T 29-03-2018 GBCGDNIH2_RS06920 82f457748b95b19c34374a03373b6d98 644 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 234 255 2.3E-62 T 29-03-2018 GBCGDNIH2_RS06920 82f457748b95b19c34374a03373b6d98 644 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 324 336 2.3E-62 T 29-03-2018 GBCGDNIH2_RS06920 82f457748b95b19c34374a03373b6d98 644 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 83 108 2.3E-62 T 29-03-2018 GBCGDNIH2_RS06920 82f457748b95b19c34374a03373b6d98 644 Pfam PF00361 Proton-conducting membrane transporter 135 428 7.5E-95 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS06920 82f457748b95b19c34374a03373b6d98 644 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 2 640 6.3E-250 T 29-03-2018 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS06240 ae4f4d888383772655ba138d783517e9 315 Gene3D G3DSA:3.40.190.10 116 201 9.5E-12 T 29-03-2018 GBCGDNIH2_RS06240 ae4f4d888383772655ba138d783517e9 315 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 34 90 2.4E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS06240 ae4f4d888383772655ba138d783517e9 315 Pfam PF03466 LysR substrate binding domain 117 313 2.7E-25 T 29-03-2018 IPR005119 LysR, substrate-binding GBCGDNIH2_RS06240 ae4f4d888383772655ba138d783517e9 315 Gene3D G3DSA:3.40.190.10 202 282 4.1E-9 T 29-03-2018 GBCGDNIH2_RS06240 ae4f4d888383772655ba138d783517e9 315 Gene3D G3DSA:1.10.10.10 25 112 4.3E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS06240 ae4f4d888383772655ba138d783517e9 315 SUPERFAMILY SSF46785 27 138 1.03E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS06240 ae4f4d888383772655ba138d783517e9 315 SUPERFAMILY SSF53850 117 315 5.07E-29 T 29-03-2018 GBCGDNIH2_RS03465 68f3064f422d734d9c189afa8f5f966d 175 Pfam PF02627 Carboxymuconolactone decarboxylase family 94 173 1.1E-16 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 GBCGDNIH2_RS03465 68f3064f422d734d9c189afa8f5f966d 175 SUPERFAMILY SSF69118 3 174 4.32E-48 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 GBCGDNIH2_RS03465 68f3064f422d734d9c189afa8f5f966d 175 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 111 159 8.1E-16 T 29-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 GBCGDNIH2_RS03465 68f3064f422d734d9c189afa8f5f966d 175 Hamap MF_01676 Alkyl hydroperoxide reductase AhpD [ahpD]. 1 175 82.986 T 29-03-2018 IPR004674 Alkylhydroperoxidase AhpD GO:0006979|GO:0032843|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 GBCGDNIH2_RS03465 68f3064f422d734d9c189afa8f5f966d 175 TIGRFAM TIGR00777 ahpD: alkylhydroperoxidase, AhpD family 2 175 2.8E-71 T 29-03-2018 IPR004674 Alkylhydroperoxidase AhpD GO:0006979|GO:0032843|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 GBCGDNIH2_RS03465 68f3064f422d734d9c189afa8f5f966d 175 Gene3D G3DSA:1.20.1290.10 1 175 1.3E-45 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 GBCGDNIH2_RS05025 b6a0e93d233d57f63fadc6bac9b32417 547 PIRSF PIRSF036626 1 544 2.1E-138 T 29-03-2018 IPR012184 Bifunctional molybdopterin binding protein /nucleotidyl transferase, putative GBCGDNIH2_RS05025 b6a0e93d233d57f63fadc6bac9b32417 547 Gene3D G3DSA:3.90.550.10 346 542 6.5E-35 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS05025 b6a0e93d233d57f63fadc6bac9b32417 547 Gene3D G3DSA:3.40.980.10 130 304 2.4E-15 T 29-03-2018 IPR001453 MoaB/Mog domain GBCGDNIH2_RS05025 b6a0e93d233d57f63fadc6bac9b32417 547 SUPERFAMILY SSF53218 191 303 5.37E-12 T 29-03-2018 IPR001453 MoaB/Mog domain GBCGDNIH2_RS05025 b6a0e93d233d57f63fadc6bac9b32417 547 SUPERFAMILY SSF53448 349 538 7.89E-34 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS05025 b6a0e93d233d57f63fadc6bac9b32417 547 Pfam PF12804 MobA-like NTP transferase domain 353 513 1.2E-39 T 29-03-2018 IPR025877 MobA-like NTP transferase GBCGDNIH2_RS01835 1b33100ee8859e77a15440bacd5d0042 478 SMART SM00387 372 471 3.9E-7 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS01835 1b33100ee8859e77a15440bacd5d0042 478 Pfam PF07730 Histidine kinase 263 333 1.1E-7 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 GBCGDNIH2_RS01835 1b33100ee8859e77a15440bacd5d0042 478 SUPERFAMILY SSF55874 330 469 8.9E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS01835 1b33100ee8859e77a15440bacd5d0042 478 Gene3D G3DSA:3.30.565.10 330 477 1.3E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS01835 1b33100ee8859e77a15440bacd5d0042 478 SMART SM00304 196 247 8.3E-5 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 GBCGDNIH2_RS07020 50f7abee57eaf9589ba5c88165601249 418 SUPERFAMILY SSF52540 61 397 1.67E-74 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS07020 50f7abee57eaf9589ba5c88165601249 418 SMART SM00994 10 49 1.7E-24 T 29-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 GBCGDNIH2_RS07020 50f7abee57eaf9589ba5c88165601249 418 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 312 389 1.9E-14 T 29-03-2018 IPR019489 Clp ATPase, C-terminal GBCGDNIH2_RS07020 50f7abee57eaf9589ba5c88165601249 418 SMART SM00382 108 328 1.4E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS07020 50f7abee57eaf9589ba5c88165601249 418 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 8 405 1.8E-198 T 29-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 GBCGDNIH2_RS07020 50f7abee57eaf9589ba5c88165601249 418 SUPERFAMILY SSF57716 11 46 1.17E-11 T 29-03-2018 GBCGDNIH2_RS07020 50f7abee57eaf9589ba5c88165601249 418 Gene3D G3DSA:1.10.8.60 312 403 7.8E-30 T 29-03-2018 GBCGDNIH2_RS07020 50f7abee57eaf9589ba5c88165601249 418 SMART SM01086 312 404 4.9E-29 T 29-03-2018 IPR019489 Clp ATPase, C-terminal GBCGDNIH2_RS07020 50f7abee57eaf9589ba5c88165601249 418 Pfam PF07724 AAA domain (Cdc48 subfamily) 109 305 3.8E-50 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 GBCGDNIH2_RS07020 50f7abee57eaf9589ba5c88165601249 418 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 410 52.894 T 29-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 GBCGDNIH2_RS07020 50f7abee57eaf9589ba5c88165601249 418 Pfam PF06689 ClpX C4-type zinc finger 11 48 5.9E-20 T 29-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 GBCGDNIH2_RS07020 50f7abee57eaf9589ba5c88165601249 418 Gene3D G3DSA:3.40.50.300 54 310 5.2E-69 T 29-03-2018 GBCGDNIH2_RS12220 cfe2c0acc2f5335197115a356108e1d4 1659 Gene3D G3DSA:1.50.10.20 1155 1439 2.0E-21 T 29-03-2018 GBCGDNIH2_RS12220 cfe2c0acc2f5335197115a356108e1d4 1659 Pfam PF01835 MG2 domain 387 483 1.1E-21 T 29-03-2018 IPR002890 Alpha-2-macroglobulin, N-terminal GO:0004866 GBCGDNIH2_RS12220 cfe2c0acc2f5335197115a356108e1d4 1659 SUPERFAMILY SSF48239 1157 1435 9.42E-24 T 29-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid GBCGDNIH2_RS12220 cfe2c0acc2f5335197115a356108e1d4 1659 Pfam PF00207 Alpha-2-macroglobulin family 960 1033 6.1E-8 T 29-03-2018 IPR001599 Alpha-2-macroglobulin GO:0004866 GBCGDNIH2_RS12220 cfe2c0acc2f5335197115a356108e1d4 1659 SMART SM01359 747 894 1.6E-37 T 29-03-2018 IPR011625 Alpha-2-macroglobulin, N-terminal 2 GBCGDNIH2_RS12220 cfe2c0acc2f5335197115a356108e1d4 1659 PIRSF PIRSF038980 3 1659 0.0 T 29-03-2018 IPR026284 Alpha-2-macroglobulin domain protein, bacteria GBCGDNIH2_RS12220 cfe2c0acc2f5335197115a356108e1d4 1659 Gene3D G3DSA:2.60.40.10 387 473 3.8E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold GBCGDNIH2_RS12220 cfe2c0acc2f5335197115a356108e1d4 1659 SMART SM01360 957 1046 8.5E-26 T 29-03-2018 IPR001599 Alpha-2-macroglobulin GO:0004866 GBCGDNIH2_RS12220 cfe2c0acc2f5335197115a356108e1d4 1659 Pfam PF07703 Alpha-2-macroglobulin family N-terminal region 748 894 1.2E-16 T 29-03-2018 IPR011625 Alpha-2-macroglobulin, N-terminal 2 GBCGDNIH2_RS12220 cfe2c0acc2f5335197115a356108e1d4 1659 Pfam PF11974 Alpha-2-macroglobulin MG1 domain 280 380 3.3E-22 T 29-03-2018 GBCGDNIH2_RS11985 7769a4c642b456052c3e74bc284cf54d 192 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 14 165 5.4E-41 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 GBCGDNIH2_RS11985 7769a4c642b456052c3e74bc284cf54d 192 Gene3D G3DSA:3.40.50.1240 12 180 2.1E-37 T 29-03-2018 IPR029033 Histidine phosphatase superfamily GBCGDNIH2_RS11985 7769a4c642b456052c3e74bc284cf54d 192 SMART SM00855 13 156 6.8E-18 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 GBCGDNIH2_RS11985 7769a4c642b456052c3e74bc284cf54d 192 SUPERFAMILY SSF53254 14 179 5.55E-40 T 29-03-2018 IPR029033 Histidine phosphatase superfamily GBCGDNIH2_RS08830 1d629803f34add337d58bff5cff95c8e 369 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 247 266 - T 29-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 GBCGDNIH2_RS08830 1d629803f34add337d58bff5cff95c8e 369 SUPERFAMILY SSF53659 4 367 1.07E-111 T 29-03-2018 GBCGDNIH2_RS08830 1d629803f34add337d58bff5cff95c8e 369 SMART SM01329 6 361 4.1E-184 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 GBCGDNIH2_RS08830 1d629803f34add337d58bff5cff95c8e 369 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 5 365 49.559 T 29-03-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 GBCGDNIH2_RS08830 1d629803f34add337d58bff5cff95c8e 369 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 7 361 5.5E-142 T 29-03-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 GBCGDNIH2_RS08830 1d629803f34add337d58bff5cff95c8e 369 Gene3D G3DSA:3.40.718.10 1 369 7.2E-117 T 29-03-2018 GBCGDNIH2_RS08830 1d629803f34add337d58bff5cff95c8e 369 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 7 361 1.5E-127 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 GBCGDNIH2_RS11970 89262e57f7c6e4794a2cb250d363ae2d 265 SUPERFAMILY SSF64438 20 258 1.83E-64 T 29-03-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic GBCGDNIH2_RS11970 89262e57f7c6e4794a2cb250d363ae2d 265 Gene3D G3DSA:3.60.140.10 3 262 8.4E-69 T 29-03-2018 GBCGDNIH2_RS11970 89262e57f7c6e4794a2cb250d363ae2d 265 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 26 257 1.4E-60 T 29-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase GBCGDNIH2_RS05980 727d0416bd594b72d279caaa85fd8c60 452 Gene3D G3DSA:2.130.10.150 185 267 2.3E-6 T 29-03-2018 GBCGDNIH2_RS05980 727d0416bd594b72d279caaa85fd8c60 452 Pfam PF07676 WD40-like Beta Propeller Repeat 264 294 1.2E-6 T 29-03-2018 IPR011659 WD40-like Beta Propeller GBCGDNIH2_RS05980 727d0416bd594b72d279caaa85fd8c60 452 Pfam PF07676 WD40-like Beta Propeller Repeat 303 338 3.3E-10 T 29-03-2018 IPR011659 WD40-like Beta Propeller GBCGDNIH2_RS05980 727d0416bd594b72d279caaa85fd8c60 452 Pfam PF07676 WD40-like Beta Propeller Repeat 347 372 9.2E-4 T 29-03-2018 IPR011659 WD40-like Beta Propeller GBCGDNIH2_RS05980 727d0416bd594b72d279caaa85fd8c60 452 Hamap MF_00671 Protein TolB [tolB]. 32 447 29.647 T 29-03-2018 IPR014167 Tol-Pal system beta propeller repeat-containing protein, TolB GO:0017038|GO:0042597 GBCGDNIH2_RS05980 727d0416bd594b72d279caaa85fd8c60 452 Pfam PF04052 TolB amino-terminal domain 52 150 2.9E-29 T 29-03-2018 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 GBCGDNIH2_RS05980 727d0416bd594b72d279caaa85fd8c60 452 Gene3D G3DSA:3.40.50.10070 51 184 8.2E-31 T 29-03-2018 GBCGDNIH2_RS05980 727d0416bd594b72d279caaa85fd8c60 452 SUPERFAMILY SSF69304 177 449 5.36E-55 T 29-03-2018 GBCGDNIH2_RS05980 727d0416bd594b72d279caaa85fd8c60 452 Gene3D G3DSA:2.60.120.20 268 301 2.8E-4 T 29-03-2018 GBCGDNIH2_RS05980 727d0416bd594b72d279caaa85fd8c60 452 Gene3D G3DSA:2.60.120.20 302 352 3.7E-17 T 29-03-2018 GBCGDNIH2_RS05980 727d0416bd594b72d279caaa85fd8c60 452 Gene3D G3DSA:2.60.120.20 353 386 2.9E-6 T 29-03-2018 GBCGDNIH2_RS05980 727d0416bd594b72d279caaa85fd8c60 452 Gene3D G3DSA:2.140.10.30 387 451 2.1E-6 T 29-03-2018 GBCGDNIH2_RS05980 727d0416bd594b72d279caaa85fd8c60 452 SUPERFAMILY SSF52964 59 182 1.57E-37 T 29-03-2018 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 GBCGDNIH2_RS05980 727d0416bd594b72d279caaa85fd8c60 452 TIGRFAM TIGR02800 propeller_TolB: Tol-Pal system beta propeller repeat protein TolB 43 448 3.1E-126 T 29-03-2018 IPR014167 Tol-Pal system beta propeller repeat-containing protein, TolB GO:0017038|GO:0042597 GBCGDNIH2_RS09445 ea80e05e2f4c103ace6468c3bd7faa2c 865 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 711 725 2.6E-41 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 GBCGDNIH2_RS09445 ea80e05e2f4c103ace6468c3bd7faa2c 865 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 604 622 2.6E-41 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 GBCGDNIH2_RS09445 ea80e05e2f4c103ace6468c3bd7faa2c 865 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 678 696 2.6E-41 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 GBCGDNIH2_RS09445 ea80e05e2f4c103ace6468c3bd7faa2c 865 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 649 667 2.6E-41 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 GBCGDNIH2_RS09445 ea80e05e2f4c103ace6468c3bd7faa2c 865 SUPERFAMILY SSF52540 549 849 1.08E-82 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS09445 ea80e05e2f4c103ace6468c3bd7faa2c 865 Gene3D G3DSA:3.40.50.300 158 343 2.0E-23 T 29-03-2018 GBCGDNIH2_RS09445 ea80e05e2f4c103ace6468c3bd7faa2c 865 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 204 317 4.4E-12 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 GBCGDNIH2_RS09445 ea80e05e2f4c103ace6468c3bd7faa2c 865 Gene3D G3DSA:3.40.50.300 555 768 1.0E-52 T 29-03-2018 GBCGDNIH2_RS09445 ea80e05e2f4c103ace6468c3bd7faa2c 865 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 295 307 - T 29-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 GBCGDNIH2_RS09445 ea80e05e2f4c103ace6468c3bd7faa2c 865 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 769 849 3.2E-26 T 29-03-2018 IPR019489 Clp ATPase, C-terminal GBCGDNIH2_RS09445 ea80e05e2f4c103ace6468c3bd7faa2c 865 Gene3D G3DSA:1.10.8.60 344 550 1.6E-46 T 29-03-2018 GBCGDNIH2_RS09445 ea80e05e2f4c103ace6468c3bd7faa2c 865 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 68 7.5E-12 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 GBCGDNIH2_RS09445 ea80e05e2f4c103ace6468c3bd7faa2c 865 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 95 145 9.8E-10 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 GBCGDNIH2_RS09445 ea80e05e2f4c103ace6468c3bd7faa2c 865 SUPERFAMILY SSF52540 158 548 1.05E-100 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS09445 ea80e05e2f4c103ace6468c3bd7faa2c 865 SMART SM01086 769 858 1.5E-35 T 29-03-2018 IPR019489 Clp ATPase, C-terminal GBCGDNIH2_RS09445 ea80e05e2f4c103ace6468c3bd7faa2c 865 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 856 0.0 T 29-03-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0016485 GBCGDNIH2_RS09445 ea80e05e2f4c103ace6468c3bd7faa2c 865 Gene3D G3DSA:1.10.1780.10 1 152 5.9E-36 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 GBCGDNIH2_RS09445 ea80e05e2f4c103ace6468c3bd7faa2c 865 Pfam PF07724 AAA domain (Cdc48 subfamily) 599 763 6.9E-55 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 GBCGDNIH2_RS09445 ea80e05e2f4c103ace6468c3bd7faa2c 865 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 634 652 - T 29-03-2018 IPR028299 ClpA/B, conserved site 2 GBCGDNIH2_RS09445 ea80e05e2f4c103ace6468c3bd7faa2c 865 SUPERFAMILY SSF81923 4 156 4.05E-39 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 GBCGDNIH2_RS09445 ea80e05e2f4c103ace6468c3bd7faa2c 865 SMART SM00382 600 751 7.1E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS09445 ea80e05e2f4c103ace6468c3bd7faa2c 865 SMART SM00382 199 344 1.2E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS09445 ea80e05e2f4c103ace6468c3bd7faa2c 865 Gene3D G3DSA:1.10.8.60 769 863 2.2E-24 T 29-03-2018 GBCGDNIH2_RS08640 80f54104cdc0182af87190a540ec92a2 748 SUPERFAMILY SSF52317 281 554 2.98E-50 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like GBCGDNIH2_RS08640 80f54104cdc0182af87190a540ec92a2 748 Gene3D G3DSA:3.40.50.410 67 117 0.12 T 29-03-2018 IPR002035 von Willebrand factor, type A GBCGDNIH2_RS08640 80f54104cdc0182af87190a540ec92a2 748 Gene3D G3DSA:3.40.50.880 297 576 1.5E-34 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like GBCGDNIH2_RS07960 b52a17cd893aa3e96826ff180144d4d2 275 SUPERFAMILY SSF54506 3 127 4.19E-38 T 29-03-2018 GBCGDNIH2_RS07960 b52a17cd893aa3e96826ff180144d4d2 275 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 3 269 1.8E-72 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 GBCGDNIH2_RS07960 b52a17cd893aa3e96826ff180144d4d2 275 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 3 270 33.853 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 GBCGDNIH2_RS07960 b52a17cd893aa3e96826ff180144d4d2 275 Gene3D G3DSA:3.10.310.10 122 257 1.4E-43 T 29-03-2018 GBCGDNIH2_RS07960 b52a17cd893aa3e96826ff180144d4d2 275 SUPERFAMILY SSF54506 142 268 3.59E-47 T 29-03-2018 GBCGDNIH2_RS07960 b52a17cd893aa3e96826ff180144d4d2 275 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 65 79 - T 29-03-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 GBCGDNIH2_RS07960 b52a17cd893aa3e96826ff180144d4d2 275 Gene3D G3DSA:3.10.310.10 1 121 1.3E-40 T 29-03-2018 GBCGDNIH2_RS07960 b52a17cd893aa3e96826ff180144d4d2 275 Pfam PF01678 Diaminopimelate epimerase 5 118 1.3E-20 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 GBCGDNIH2_RS07960 b52a17cd893aa3e96826ff180144d4d2 275 Pfam PF01678 Diaminopimelate epimerase 149 262 5.1E-25 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 GBCGDNIH2_RS00490 71d4a7b9de5c13ce70df9d792e7c01d5 293 Gene3D G3DSA:3.30.1150.10 56 293 1.5E-18 T 29-03-2018 GBCGDNIH2_RS00490 71d4a7b9de5c13ce70df9d792e7c01d5 293 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 215 290 1.5E-22 T 29-03-2018 IPR006260 TonB, C-terminal GO:0006810 GBCGDNIH2_RS00490 71d4a7b9de5c13ce70df9d792e7c01d5 293 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 216 280 1.2E-16 T 29-03-2018 IPR006260 TonB, C-terminal GO:0006810 GBCGDNIH2_RS00490 71d4a7b9de5c13ce70df9d792e7c01d5 293 SUPERFAMILY SSF74653 211 290 1.7E-21 T 29-03-2018 GBCGDNIH2_RS05250 a6697deb0b6fe45ccacc6e5a4d5cf320 306 Gene3D G3DSA:3.30.360.10 132 286 1.9E-41 T 29-03-2018 GBCGDNIH2_RS05250 a6697deb0b6fe45ccacc6e5a4d5cf320 306 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 46 107 1.6E-5 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 GBCGDNIH2_RS05250 a6697deb0b6fe45ccacc6e5a4d5cf320 306 SUPERFAMILY SSF51735 4 139 1.69E-21 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS05250 a6697deb0b6fe45ccacc6e5a4d5cf320 306 Hamap MF_01110 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 4 305 50.588 T 29-03-2018 IPR010136 N-acetyl-gamma-glutamyl-phosphate reductase, type 2 GO:0003942|GO:0005737|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 GBCGDNIH2_RS05250 a6697deb0b6fe45ccacc6e5a4d5cf320 306 SUPERFAMILY SSF55347 122 286 4.25E-34 T 29-03-2018 GBCGDNIH2_RS05250 a6697deb0b6fe45ccacc6e5a4d5cf320 306 SMART SM00859 7 111 1.2E-12 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 GBCGDNIH2_RS05250 a6697deb0b6fe45ccacc6e5a4d5cf320 306 Gene3D G3DSA:3.40.50.720 21 131 5.6E-13 T 29-03-2018 GBCGDNIH2_RS05250 a6697deb0b6fe45ccacc6e5a4d5cf320 306 TIGRFAM TIGR01851 argC_other: N-acetyl-gamma-glutamyl-phosphate reductase 7 305 1.7E-102 T 29-03-2018 IPR010136 N-acetyl-gamma-glutamyl-phosphate reductase, type 2 GO:0003942|GO:0005737|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 GBCGDNIH2_RS04085 2297af5bb2c2479adb1b9aae1648031f 717 Gene3D G3DSA:3.30.365.10 577 717 3.2E-33 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 GBCGDNIH2_RS04085 2297af5bb2c2479adb1b9aae1648031f 717 Gene3D G3DSA:3.90.1170.50 186 324 7.9E-36 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead GBCGDNIH2_RS04085 2297af5bb2c2479adb1b9aae1648031f 717 Gene3D G3DSA:3.30.365.10 325 418 1.1E-27 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 GBCGDNIH2_RS04085 2297af5bb2c2479adb1b9aae1648031f 717 SUPERFAMILY SSF56003 13 243 4.88E-39 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 GBCGDNIH2_RS04085 2297af5bb2c2479adb1b9aae1648031f 717 SUPERFAMILY SSF56003 310 709 6.28E-114 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 GBCGDNIH2_RS04085 2297af5bb2c2479adb1b9aae1648031f 717 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 312 547 1.5E-34 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 GBCGDNIH2_RS04085 2297af5bb2c2479adb1b9aae1648031f 717 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 45 192 4.4E-10 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 GBCGDNIH2_RS04085 2297af5bb2c2479adb1b9aae1648031f 717 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 585 664 1.2E-17 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 GBCGDNIH2_RS04085 2297af5bb2c2479adb1b9aae1648031f 717 SMART SM01008 209 287 1.7E-21 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead GBCGDNIH2_RS04085 2297af5bb2c2479adb1b9aae1648031f 717 Gene3D G3DSA:3.30.365.10 419 576 1.5E-37 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 GBCGDNIH2_RS04085 2297af5bb2c2479adb1b9aae1648031f 717 PIRSF PIRSF036389 1 715 4.8E-248 T 29-03-2018 IPR012368 Oxidoreductase molybdopterin-binding subunit, IorB-related GBCGDNIH2_RS04085 2297af5bb2c2479adb1b9aae1648031f 717 Gene3D G3DSA:3.30.365.10 29 185 5.2E-34 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 GBCGDNIH2_RS01475 cafdf831004945ff1a3f82cf78da7f8f 690 Pfam PF02540 NAD synthase 355 549 3.7E-23 T 29-03-2018 IPR022310 NAD/GMP synthase GBCGDNIH2_RS01475 cafdf831004945ff1a3f82cf78da7f8f 690 Gene3D G3DSA:3.60.110.10 13 362 1.0E-74 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 GBCGDNIH2_RS01475 cafdf831004945ff1a3f82cf78da7f8f 690 TIGRFAM TIGR00552 nadE: NAD+ synthetase 359 527 2.1E-19 T 29-03-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 GBCGDNIH2_RS01475 cafdf831004945ff1a3f82cf78da7f8f 690 Gene3D G3DSA:3.40.50.620 363 678 1.0E-51 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GBCGDNIH2_RS01475 cafdf831004945ff1a3f82cf78da7f8f 690 SUPERFAMILY SSF56317 20 301 5.62E-48 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 GBCGDNIH2_RS01475 cafdf831004945ff1a3f82cf78da7f8f 690 Pfam PF00795 Carbon-nitrogen hydrolase 22 288 8.3E-17 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 GBCGDNIH2_RS01475 cafdf831004945ff1a3f82cf78da7f8f 690 PIRSF PIRSF006630 18 678 1.1E-157 T 29-03-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 GBCGDNIH2_RS01475 cafdf831004945ff1a3f82cf78da7f8f 690 SUPERFAMILY SSF52402 624 655 3.72E-66 T 29-03-2018 GBCGDNIH2_RS01475 cafdf831004945ff1a3f82cf78da7f8f 690 SUPERFAMILY SSF52402 332 583 3.72E-66 T 29-03-2018 GBCGDNIH2_RS01000 2aff7829ec7154ab2fec12df9359b7b0 408 Gene3D G3DSA:3.40.50.2000 12 199 9.0E-4 T 29-03-2018 GBCGDNIH2_RS01000 2aff7829ec7154ab2fec12df9359b7b0 408 Pfam PF00534 Glycosyl transferases group 1 210 381 4.8E-17 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 GBCGDNIH2_RS01000 2aff7829ec7154ab2fec12df9359b7b0 408 SUPERFAMILY SSF53756 17 403 3.02E-42 T 29-03-2018 GBCGDNIH2_RS01000 2aff7829ec7154ab2fec12df9359b7b0 408 Pfam PF12000 Gkycosyl transferase family 4 group 26 191 7.4E-55 T 29-03-2018 IPR022623 Domain of unknown function DUF3495 GBCGDNIH2_RS01000 2aff7829ec7154ab2fec12df9359b7b0 408 Gene3D G3DSA:3.40.50.2000 200 383 3.2E-29 T 29-03-2018 GBCGDNIH2_RS11135 05797c5c00b085d3a2d74e9016ae9d48 224 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 10 219 4.7E-87 T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 GBCGDNIH2_RS11135 05797c5c00b085d3a2d74e9016ae9d48 224 Pfam PF00834 Ribulose-phosphate 3 epimerase family 10 204 8.6E-83 T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 GBCGDNIH2_RS11135 05797c5c00b085d3a2d74e9016ae9d48 224 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 139 161 - T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 GBCGDNIH2_RS11135 05797c5c00b085d3a2d74e9016ae9d48 224 SUPERFAMILY SSF51366 8 220 7.4E-73 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 GBCGDNIH2_RS11135 05797c5c00b085d3a2d74e9016ae9d48 224 Gene3D G3DSA:3.20.20.70 1 222 2.2E-86 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS11135 05797c5c00b085d3a2d74e9016ae9d48 224 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 37 51 - T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 GBCGDNIH2_RS11135 05797c5c00b085d3a2d74e9016ae9d48 224 PIRSF PIRSF001461 4 224 9.8E-92 T 29-03-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 GBCGDNIH2_RS07925 64b50b22cce9c1c4eee327f5e66d8d9a 518 SMART SM00065 148 320 8.5E-8 T 29-03-2018 IPR003018 GAF domain GO:0005515 GBCGDNIH2_RS07925 64b50b22cce9c1c4eee327f5e66d8d9a 518 Gene3D G3DSA:3.30.450.20 4 122 1.1E-18 T 29-03-2018 GBCGDNIH2_RS07925 64b50b22cce9c1c4eee327f5e66d8d9a 518 SUPERFAMILY SSF55785 5 121 1.41E-27 T 29-03-2018 IPR000014 PAS domain GBCGDNIH2_RS07925 64b50b22cce9c1c4eee327f5e66d8d9a 518 PRINTS PR01033 Phytochrome signature 248 269 1.6E-15 T 29-03-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 GBCGDNIH2_RS07925 64b50b22cce9c1c4eee327f5e66d8d9a 518 PRINTS PR01033 Phytochrome signature 46 68 1.6E-15 T 29-03-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 GBCGDNIH2_RS07925 64b50b22cce9c1c4eee327f5e66d8d9a 518 PRINTS PR01033 Phytochrome signature 344 364 1.6E-15 T 29-03-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 GBCGDNIH2_RS07925 64b50b22cce9c1c4eee327f5e66d8d9a 518 PRINTS PR01033 Phytochrome signature 429 448 1.6E-15 T 29-03-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 GBCGDNIH2_RS07925 64b50b22cce9c1c4eee327f5e66d8d9a 518 PRINTS PR01033 Phytochrome signature 462 480 1.6E-15 T 29-03-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 GBCGDNIH2_RS07925 64b50b22cce9c1c4eee327f5e66d8d9a 518 SUPERFAMILY SSF55781 326 502 7.95E-42 T 29-03-2018 IPR029016 GAF domain-like GBCGDNIH2_RS07925 64b50b22cce9c1c4eee327f5e66d8d9a 518 Pfam PF01590 GAF domain 152 307 1.4E-17 T 29-03-2018 IPR003018 GAF domain GO:0005515 GBCGDNIH2_RS07925 64b50b22cce9c1c4eee327f5e66d8d9a 518 SUPERFAMILY SSF55781 139 314 4.66E-54 T 29-03-2018 IPR029016 GAF domain-like GBCGDNIH2_RS07925 64b50b22cce9c1c4eee327f5e66d8d9a 518 Pfam PF08446 PAS fold 13 121 5.5E-14 T 29-03-2018 IPR013654 PAS fold-2 GO:0006355 GBCGDNIH2_RS07925 64b50b22cce9c1c4eee327f5e66d8d9a 518 Pfam PF00360 Phytochrome region 342 502 8.7E-41 T 29-03-2018 IPR013515 Phytochrome, central region GO:0006355|GO:0009584|GO:0018298 GBCGDNIH2_RS07925 64b50b22cce9c1c4eee327f5e66d8d9a 518 Gene3D G3DSA:3.30.450.40 133 314 2.4E-37 T 29-03-2018 IPR029016 GAF domain-like GBCGDNIH2_RS06420 25cb4c0dae63973186cf2fc80c627d10 292 Pfam PF02274 Amidinotransferase 74 287 1.2E-17 T 29-03-2018 GBCGDNIH2_RS06420 25cb4c0dae63973186cf2fc80c627d10 292 Gene3D G3DSA:3.75.10.10 11 287 3.1E-48 T 29-03-2018 GBCGDNIH2_RS06420 25cb4c0dae63973186cf2fc80c627d10 292 SUPERFAMILY SSF55909 10 290 4.12E-53 T 29-03-2018 GBCGDNIH2_RS10875 b35000f620faf70b714395a7b921d558 728 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 267 281 1.6E-24 T 29-03-2018 GBCGDNIH2_RS10875 b35000f620faf70b714395a7b921d558 728 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 417 431 1.6E-24 T 29-03-2018 GBCGDNIH2_RS10875 b35000f620faf70b714395a7b921d558 728 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 565 575 1.6E-24 T 29-03-2018 GBCGDNIH2_RS10875 b35000f620faf70b714395a7b921d558 728 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 641 653 1.6E-24 T 29-03-2018 GBCGDNIH2_RS10875 b35000f620faf70b714395a7b921d558 728 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 618 637 1.6E-24 T 29-03-2018 GBCGDNIH2_RS10875 b35000f620faf70b714395a7b921d558 728 SUPERFAMILY SSF56784 415 435 1.13E-51 T 29-03-2018 IPR023214 HAD-like domain GBCGDNIH2_RS10875 b35000f620faf70b714395a7b921d558 728 SUPERFAMILY SSF56784 478 718 1.13E-51 T 29-03-2018 IPR023214 HAD-like domain GBCGDNIH2_RS10875 b35000f620faf70b714395a7b921d558 728 Gene3D G3DSA:1.20.1110.10 171 430 4.9E-46 T 29-03-2018 GBCGDNIH2_RS10875 b35000f620faf70b714395a7b921d558 728 Gene3D G3DSA:1.20.1110.10 585 727 1.8E-29 T 29-03-2018 GBCGDNIH2_RS10875 b35000f620faf70b714395a7b921d558 728 SUPERFAMILY SSF55008 6 77 4.06E-17 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 GBCGDNIH2_RS10875 b35000f620faf70b714395a7b921d558 728 PRINTS PR00943 Copper-transporting ATPase signature 140 159 2.6E-8 T 29-03-2018 GBCGDNIH2_RS10875 b35000f620faf70b714395a7b921d558 728 PRINTS PR00943 Copper-transporting ATPase signature 340 354 2.6E-8 T 29-03-2018 GBCGDNIH2_RS10875 b35000f620faf70b714395a7b921d558 728 PRINTS PR00943 Copper-transporting ATPase signature 400 415 2.6E-8 T 29-03-2018 GBCGDNIH2_RS10875 b35000f620faf70b714395a7b921d558 728 PRINTS PR00943 Copper-transporting ATPase signature 595 612 2.6E-8 T 29-03-2018 GBCGDNIH2_RS10875 b35000f620faf70b714395a7b921d558 728 SUPERFAMILY SSF81653 220 317 2.75E-22 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 GBCGDNIH2_RS10875 b35000f620faf70b714395a7b921d558 728 Gene3D G3DSA:3.40.1110.10 431 584 1.3E-32 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 GBCGDNIH2_RS10875 b35000f620faf70b714395a7b921d558 728 Pfam PF00122 E1-E2 ATPase 218 397 5.4E-54 T 29-03-2018 GBCGDNIH2_RS10875 b35000f620faf70b714395a7b921d558 728 Pfam PF00403 Heavy-metal-associated domain 15 71 6.0E-11 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 GBCGDNIH2_RS10875 b35000f620faf70b714395a7b921d558 728 Pfam PF00702 haloacid dehalogenase-like hydrolase 413 632 2.3E-31 T 29-03-2018 GBCGDNIH2_RS10875 b35000f620faf70b714395a7b921d558 728 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 155 720 4.5E-172 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 GBCGDNIH2_RS10875 b35000f620faf70b714395a7b921d558 728 ProSitePatterns PS01047 Heavy-metal-associated domain. 17 46 - T 29-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 GBCGDNIH2_RS10875 b35000f620faf70b714395a7b921d558 728 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 419 425 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 GBCGDNIH2_RS10875 b35000f620faf70b714395a7b921d558 728 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 190 699 1.5E-76 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 GBCGDNIH2_RS10875 b35000f620faf70b714395a7b921d558 728 Gene3D G3DSA:3.30.70.100 9 96 2.0E-19 T 29-03-2018 GBCGDNIH2_RS10875 b35000f620faf70b714395a7b921d558 728 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 137 721 1.9E-162 T 29-03-2018 GBCGDNIH2_RS10875 b35000f620faf70b714395a7b921d558 728 SUPERFAMILY SSF81665 318 411 6.67E-16 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 GBCGDNIH2_RS10875 b35000f620faf70b714395a7b921d558 728 SUPERFAMILY SSF81665 667 694 6.67E-16 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 GBCGDNIH2_RS10875 b35000f620faf70b714395a7b921d558 728 SUPERFAMILY SSF81665 171 217 6.67E-16 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 GBCGDNIH2_RS02130 727e496faca799f2d903b016424e9ef0 330 SMART SM00354 3 72 6.9E-27 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 GBCGDNIH2_RS02130 727e496faca799f2d903b016424e9ef0 330 Pfam PF00356 Bacterial regulatory proteins, lacI family 6 49 2.9E-14 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 GBCGDNIH2_RS02130 727e496faca799f2d903b016424e9ef0 330 SUPERFAMILY SSF47413 2 60 1.03E-13 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GBCGDNIH2_RS02130 727e496faca799f2d903b016424e9ef0 330 Gene3D G3DSA:1.10.260.40 4 54 1.1E-19 T 29-03-2018 GBCGDNIH2_RS02130 727e496faca799f2d903b016424e9ef0 330 Gene3D G3DSA:3.40.50.2300 174 304 2.6E-36 T 29-03-2018 GBCGDNIH2_RS02130 727e496faca799f2d903b016424e9ef0 330 Pfam PF13377 Periplasmic binding protein-like domain 168 325 4.2E-33 T 29-03-2018 GBCGDNIH2_RS02130 727e496faca799f2d903b016424e9ef0 330 SUPERFAMILY SSF53822 60 314 4.52E-65 T 29-03-2018 IPR028082 Periplasmic binding protein-like I GBCGDNIH2_RS02130 727e496faca799f2d903b016424e9ef0 330 ProSitePatterns PS00356 LacI-type HTH domain signature. 6 24 - T 29-03-2018 GBCGDNIH2_RS02130 727e496faca799f2d903b016424e9ef0 330 Gene3D G3DSA:3.40.50.2300 55 173 1.8E-34 T 29-03-2018 GBCGDNIH2_RS09685 5d1bc8f6666f3f5c31e1439071d0e26e 612 Gene3D G3DSA:1.25.40.10 255 424 9.6E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS09685 5d1bc8f6666f3f5c31e1439071d0e26e 612 Pfam PF01464 Transglycosylase SLT domain 441 542 1.5E-19 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 GBCGDNIH2_RS09685 5d1bc8f6666f3f5c31e1439071d0e26e 612 Gene3D G3DSA:1.25.20.10 60 249 2.4E-8 T 29-03-2018 GBCGDNIH2_RS09685 5d1bc8f6666f3f5c31e1439071d0e26e 612 SUPERFAMILY SSF53955 442 584 4.02E-35 T 29-03-2018 IPR023346 Lysozyme-like domain GBCGDNIH2_RS09685 5d1bc8f6666f3f5c31e1439071d0e26e 612 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 451 479 - T 29-03-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 GBCGDNIH2_RS09685 5d1bc8f6666f3f5c31e1439071d0e26e 612 Gene3D G3DSA:1.10.530.10 435 585 1.7E-26 T 29-03-2018 GBCGDNIH2_RS09685 5d1bc8f6666f3f5c31e1439071d0e26e 612 SUPERFAMILY SSF48435 198 421 2.62E-11 T 29-03-2018 IPR016026 Lytic transglycosylase, superhelical U-shaped and linker domain GO:0004553|GO:0042597 GBCGDNIH2_RS09380 956db667faf75118e6f6148165474449 296 SUPERFAMILY SSF53335 87 265 7.45E-28 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GBCGDNIH2_RS09380 956db667faf75118e6f6148165474449 296 Gene3D G3DSA:3.40.50.150 20 290 1.2E-22 T 29-03-2018 GBCGDNIH2_RS09380 956db667faf75118e6f6148165474449 296 Pfam PF08241 Methyltransferase domain 99 193 1.2E-14 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 GBCGDNIH2_RS00715 c611333077656fc8129a6e35c97be7a6 278 Gene3D G3DSA:1.20.59.10 1 80 1.1E-16 T 29-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 GBCGDNIH2_RS00715 c611333077656fc8129a6e35c97be7a6 278 Pfam PF01817 Chorismate mutase type II 3 76 4.0E-14 T 29-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 GBCGDNIH2_RS00715 c611333077656fc8129a6e35c97be7a6 278 SUPERFAMILY SSF48600 2 70 1.37E-12 T 29-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 GBCGDNIH2_RS00715 c611333077656fc8129a6e35c97be7a6 278 SMART SM00830 3 79 5.9E-18 T 29-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 GBCGDNIH2_RS10150 b1b42c32cd0d0d6acb7fdc1a66711758 416 Gene3D G3DSA:3.40.640.10 40 274 8.6E-52 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GBCGDNIH2_RS10150 b1b42c32cd0d0d6acb7fdc1a66711758 416 SUPERFAMILY SSF53383 32 388 7.76E-81 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase GBCGDNIH2_RS10150 b1b42c32cd0d0d6acb7fdc1a66711758 416 Gene3D G3DSA:3.90.1150.10 286 399 1.3E-24 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 GBCGDNIH2_RS10150 b1b42c32cd0d0d6acb7fdc1a66711758 416 PIRSF PIRSF005572 30 399 2.6E-105 T 29-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 GBCGDNIH2_RS10150 b1b42c32cd0d0d6acb7fdc1a66711758 416 Pfam PF00266 Aminotransferase class-V 32 385 3.3E-55 T 29-03-2018 IPR000192 Aminotransferase class V domain GBCGDNIH2_RS02965 733e09d21feaffda939a655e04e7cc32 320 Pfam PF03547 Membrane transport protein 5 150 1.5E-12 T 29-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 GBCGDNIH2_RS02965 733e09d21feaffda939a655e04e7cc32 320 Pfam PF03547 Membrane transport protein 165 316 3.9E-15 T 29-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 GBCGDNIH2_RS11895 d20336f44946b805fc167b82ba96107d 424 Gene3D G3DSA:3.40.50.20 2 84 4.2E-38 T 29-03-2018 GBCGDNIH2_RS11895 d20336f44946b805fc167b82ba96107d 424 Gene3D G3DSA:3.30.1490.20 85 187 2.0E-24 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 GBCGDNIH2_RS11895 d20336f44946b805fc167b82ba96107d 424 SMART SM01209 101 293 1.5E-127 T 29-03-2018 GBCGDNIH2_RS11895 d20336f44946b805fc167b82ba96107d 424 SUPERFAMILY SSF51246 326 421 2.12E-26 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 GBCGDNIH2_RS11895 d20336f44946b805fc167b82ba96107d 424 SUPERFAMILY SSF52440 1 101 4.6E-36 T 29-03-2018 IPR016185 Pre-ATP-grasp domain GBCGDNIH2_RS11895 d20336f44946b805fc167b82ba96107d 424 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 421 1.3E-158 T 29-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 GBCGDNIH2_RS11895 d20336f44946b805fc167b82ba96107d 424 SMART SM01210 327 421 1.4E-43 T 29-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 GBCGDNIH2_RS11895 d20336f44946b805fc167b82ba96107d 424 Gene3D G3DSA:3.30.470.20 189 325 2.2E-57 T 29-03-2018 GBCGDNIH2_RS11895 d20336f44946b805fc167b82ba96107d 424 Gene3D G3DSA:3.90.600.10 327 421 1.2E-29 T 29-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 GBCGDNIH2_RS11895 d20336f44946b805fc167b82ba96107d 424 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 421 41.638 T 29-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 GBCGDNIH2_RS11895 d20336f44946b805fc167b82ba96107d 424 SUPERFAMILY SSF56059 102 316 1.66E-58 T 29-03-2018 GBCGDNIH2_RS11895 d20336f44946b805fc167b82ba96107d 424 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 293 9.1E-75 T 29-03-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 GBCGDNIH2_RS11895 d20336f44946b805fc167b82ba96107d 424 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 328 419 2.6E-23 T 29-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 GBCGDNIH2_RS11895 d20336f44946b805fc167b82ba96107d 424 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 100 2.1E-36 T 29-03-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 GBCGDNIH2_RS11895 d20336f44946b805fc167b82ba96107d 424 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 287 294 - T 29-03-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 GBCGDNIH2_RS00810 d9fe81973703dd7a80f903ed4155c9ba 89 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 86 1.8E-24 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS00810 d9fe81973703dd7a80f903ed4155c9ba 89 Pfam PF01649 Ribosomal protein S20 2 84 2.5E-26 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS00810 d9fe81973703dd7a80f903ed4155c9ba 89 Gene3D G3DSA:1.20.58.110 1 89 3.1E-28 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS00810 d9fe81973703dd7a80f903ed4155c9ba 89 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 17.501 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS00810 d9fe81973703dd7a80f903ed4155c9ba 89 SUPERFAMILY SSF46992 3 86 6.93E-29 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS00810 d9fe81973703dd7a80f903ed4155c9ba 89 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 23 89 2.0E-21 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS04195 35f43abf53d6b08365304e34dd473c53 400 Pfam PF00994 Probable molybdopterin binding domain 174 310 2.8E-22 T 29-03-2018 IPR001453 MoaB/Mog domain GBCGDNIH2_RS04195 35f43abf53d6b08365304e34dd473c53 400 SMART SM00852 174 311 7.5E-38 T 29-03-2018 IPR001453 MoaB/Mog domain GBCGDNIH2_RS04195 35f43abf53d6b08365304e34dd473c53 400 Gene3D G3DSA:3.40.980.10 144 318 1.8E-46 T 29-03-2018 IPR001453 MoaB/Mog domain GBCGDNIH2_RS04195 35f43abf53d6b08365304e34dd473c53 400 Gene3D G3DSA:2.170.190.11 59 135 7.2E-22 T 29-03-2018 GBCGDNIH2_RS04195 35f43abf53d6b08365304e34dd473c53 400 Gene3D G3DSA:2.40.340.10 321 397 7.0E-18 T 29-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 GBCGDNIH2_RS04195 35f43abf53d6b08365304e34dd473c53 400 Gene3D G3DSA:3.90.105.10 20 58 4.5E-9 T 29-03-2018 GBCGDNIH2_RS04195 35f43abf53d6b08365304e34dd473c53 400 SUPERFAMILY SSF63867 320 397 1.7E-18 T 29-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 GBCGDNIH2_RS04195 35f43abf53d6b08365304e34dd473c53 400 SUPERFAMILY SSF63882 1 169 1.96E-46 T 29-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 GBCGDNIH2_RS04195 35f43abf53d6b08365304e34dd473c53 400 Pfam PF03453 MoeA N-terminal region (domain I and II) 2 160 2.3E-35 T 29-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 GBCGDNIH2_RS04195 35f43abf53d6b08365304e34dd473c53 400 Pfam PF03454 MoeA C-terminal region (domain IV) 325 395 1.6E-18 T 29-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 GBCGDNIH2_RS04195 35f43abf53d6b08365304e34dd473c53 400 SUPERFAMILY SSF53218 171 316 1.96E-38 T 29-03-2018 IPR001453 MoaB/Mog domain GBCGDNIH2_RS09285 e522d8850b438065c7d0b820aeb6b2cb 275 Gene3D G3DSA:3.40.50.720 1 274 5.8E-65 T 29-03-2018 GBCGDNIH2_RS09285 e522d8850b438065c7d0b820aeb6b2cb 275 Pfam PF00106 short chain dehydrogenase 3 182 1.5E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS09285 e522d8850b438065c7d0b820aeb6b2cb 275 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 131 159 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 GBCGDNIH2_RS09285 e522d8850b438065c7d0b820aeb6b2cb 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 124 132 1.2E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS09285 e522d8850b438065c7d0b820aeb6b2cb 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 71 82 1.2E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS09285 e522d8850b438065c7d0b820aeb6b2cb 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 163 1.2E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS09285 e522d8850b438065c7d0b820aeb6b2cb 275 SUPERFAMILY SSF51735 1 241 4.83E-59 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS09285 e522d8850b438065c7d0b820aeb6b2cb 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 5.2E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS09285 e522d8850b438065c7d0b820aeb6b2cb 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 134 5.2E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS09285 e522d8850b438065c7d0b820aeb6b2cb 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 5.2E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS09285 e522d8850b438065c7d0b820aeb6b2cb 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 163 5.2E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS09285 e522d8850b438065c7d0b820aeb6b2cb 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 5.2E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS09285 e522d8850b438065c7d0b820aeb6b2cb 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 71 82 5.2E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS11960 0407e677b6924470eab87b8b793a46df 278 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 12 260 2.5E-74 T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 GBCGDNIH2_RS11960 0407e677b6924470eab87b8b793a46df 278 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 9 266 18.787 T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 GBCGDNIH2_RS11960 0407e677b6924470eab87b8b793a46df 278 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 4 265 1.1E-73 T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 GBCGDNIH2_RS11960 0407e677b6924470eab87b8b793a46df 278 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 141 153 - T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 GBCGDNIH2_RS11255 68f6b72359a067513fd71b006978ea9f 216 PIRSF PIRSF005624 1 211 2.4E-50 T 29-03-2018 IPR012202 [NiFe]-hydrogenase/urease maturation factor, Ni2-binding GTPase GO:0003924|GO:0016151 GBCGDNIH2_RS11255 68f6b72359a067513fd71b006978ea9f 216 Hamap MF_01389 Urease accessory protein UreG [ureG]. 13 211 47.78 T 29-03-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 GBCGDNIH2_RS11255 68f6b72359a067513fd71b006978ea9f 216 TIGRFAM TIGR00101 ureG: urease accessory protein UreG 15 205 8.0E-104 T 29-03-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 GBCGDNIH2_RS11255 68f6b72359a067513fd71b006978ea9f 216 SUPERFAMILY SSF52540 11 206 1.19E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS11255 68f6b72359a067513fd71b006978ea9f 216 Gene3D G3DSA:3.40.50.300 13 211 3.2E-18 T 29-03-2018 GBCGDNIH2_RS11255 68f6b72359a067513fd71b006978ea9f 216 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 17 187 3.3E-36 T 29-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain GBCGDNIH2_RS12235 98faad336dd87c828197fc82fd11f6f6 1140 PRINTS PR01988 Putative bacilysin exporter bacE signature 155 176 6.5E-6 T 29-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 GBCGDNIH2_RS12235 98faad336dd87c828197fc82fd11f6f6 1140 PRINTS PR01988 Putative bacilysin exporter bacE signature 275 292 6.5E-6 T 29-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 GBCGDNIH2_RS12235 98faad336dd87c828197fc82fd11f6f6 1140 PRINTS PR01988 Putative bacilysin exporter bacE signature 115 133 6.5E-6 T 29-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 GBCGDNIH2_RS12235 98faad336dd87c828197fc82fd11f6f6 1140 Gene3D G3DSA:3.40.50.980 640 809 2.9E-23 T 29-03-2018 GBCGDNIH2_RS12235 98faad336dd87c828197fc82fd11f6f6 1140 Pfam PF01553 Acyltransferase 448 570 7.3E-12 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 GBCGDNIH2_RS12235 98faad336dd87c828197fc82fd11f6f6 1140 Gene3D G3DSA:3.40.1130.10 432 639 1.6E-22 T 29-03-2018 GBCGDNIH2_RS12235 98faad336dd87c828197fc82fd11f6f6 1140 SUPERFAMILY SSF69593 437 575 2.22E-17 T 29-03-2018 GBCGDNIH2_RS12235 98faad336dd87c828197fc82fd11f6f6 1140 Gene3D G3DSA:3.40.50.980 810 959 5.3E-40 T 29-03-2018 GBCGDNIH2_RS12235 98faad336dd87c828197fc82fd11f6f6 1140 Gene3D G3DSA:1.20.1250.20 220 431 1.1E-10 T 29-03-2018 GBCGDNIH2_RS12235 98faad336dd87c828197fc82fd11f6f6 1140 SUPERFAMILY SSF103473 10 432 1.83E-21 T 29-03-2018 IPR020846 Major facilitator superfamily domain GBCGDNIH2_RS12235 98faad336dd87c828197fc82fd11f6f6 1140 SUPERFAMILY SSF56801 627 1137 9.81E-94 T 29-03-2018 GBCGDNIH2_RS12235 98faad336dd87c828197fc82fd11f6f6 1140 Gene3D G3DSA:2.30.38.10 960 1037 1.1E-9 T 29-03-2018 GBCGDNIH2_RS12235 98faad336dd87c828197fc82fd11f6f6 1140 SMART SM00563 463 573 8.3E-18 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 GBCGDNIH2_RS12235 98faad336dd87c828197fc82fd11f6f6 1140 Pfam PF07690 Major Facilitator Superfamily 21 307 1.1E-12 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 GBCGDNIH2_RS12235 98faad336dd87c828197fc82fd11f6f6 1140 Pfam PF00501 AMP-binding enzyme 664 1044 6.7E-61 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 GBCGDNIH2_RS12235 98faad336dd87c828197fc82fd11f6f6 1140 Gene3D G3DSA:1.20.1250.20 8 204 5.1E-10 T 29-03-2018 GBCGDNIH2_RS12235 98faad336dd87c828197fc82fd11f6f6 1140 ProSitePatterns PS00455 Putative AMP-binding domain signature. 804 815 - T 29-03-2018 IPR020845 AMP-binding, conserved site GBCGDNIH2_RS12235 98faad336dd87c828197fc82fd11f6f6 1140 Gene3D G3DSA:3.30.300.30 1042 1140 2.5E-11 T 29-03-2018 GBCGDNIH2_RS12075 49498e8e0f1eedbe1935aaabecc29d90 228 Pfam PF04280 Tim44-like domain 83 226 2.5E-41 T 29-03-2018 IPR007379 Tim44-like domain GBCGDNIH2_RS12075 49498e8e0f1eedbe1935aaabecc29d90 228 SUPERFAMILY SSF54427 22 225 1.93E-43 T 29-03-2018 IPR032710 NTF2-like domain GBCGDNIH2_RS12075 49498e8e0f1eedbe1935aaabecc29d90 228 SMART SM00978 82 227 4.0E-43 T 29-03-2018 IPR007379 Tim44-like domain GBCGDNIH2_RS12075 49498e8e0f1eedbe1935aaabecc29d90 228 PIRSF PIRSF031890 7 228 1.7E-57 T 29-03-2018 IPR016985 Uncharacterised conserved protein UCP031890, Tim44-related GBCGDNIH2_RS00110 030a7f738a318530350ffb00c1bc2fec 632 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 332 346 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 GBCGDNIH2_RS00110 030a7f738a318530350ffb00c1bc2fec 632 SUPERFAMILY SSF100934 502 599 6.15E-18 T 29-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain GBCGDNIH2_RS00110 030a7f738a318530350ffb00c1bc2fec 632 Gene3D G3DSA:3.30.420.40 196 361 3.8E-49 T 29-03-2018 GBCGDNIH2_RS00110 030a7f738a318530350ffb00c1bc2fec 632 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 191 204 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 GBCGDNIH2_RS00110 030a7f738a318530350ffb00c1bc2fec 632 SUPERFAMILY SSF53067 187 377 1.54E-66 T 29-03-2018 GBCGDNIH2_RS00110 030a7f738a318530350ffb00c1bc2fec 632 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 599 5.6E-300 T 29-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 GBCGDNIH2_RS00110 030a7f738a318530350ffb00c1bc2fec 632 Gene3D G3DSA:1.20.1270.10 527 612 2.4E-22 T 29-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain GBCGDNIH2_RS00110 030a7f738a318530350ffb00c1bc2fec 632 Gene3D G3DSA:2.60.34.10 385 526 2.9E-70 T 29-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 GBCGDNIH2_RS00110 030a7f738a318530350ffb00c1bc2fec 632 Pfam PF00012 Hsp70 protein 4 599 1.4E-276 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 GBCGDNIH2_RS00110 030a7f738a318530350ffb00c1bc2fec 632 SUPERFAMILY SSF100920 379 535 1.23E-63 T 29-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 GBCGDNIH2_RS00110 030a7f738a318530350ffb00c1bc2fec 632 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 626 37.718 T 29-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 GBCGDNIH2_RS00110 030a7f738a318530350ffb00c1bc2fec 632 SUPERFAMILY SSF53067 4 184 6.15E-66 T 29-03-2018 GBCGDNIH2_RS00110 030a7f738a318530350ffb00c1bc2fec 632 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 GBCGDNIH2_RS00110 030a7f738a318530350ffb00c1bc2fec 632 PRINTS PR00301 70kDa heat shock protein signature 31 43 7.3E-81 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 GBCGDNIH2_RS00110 030a7f738a318530350ffb00c1bc2fec 632 PRINTS PR00301 70kDa heat shock protein signature 329 345 7.3E-81 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 GBCGDNIH2_RS00110 030a7f738a318530350ffb00c1bc2fec 632 PRINTS PR00301 70kDa heat shock protein signature 360 380 7.3E-81 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 GBCGDNIH2_RS00110 030a7f738a318530350ffb00c1bc2fec 632 PRINTS PR00301 70kDa heat shock protein signature 464 480 7.3E-81 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 GBCGDNIH2_RS00110 030a7f738a318530350ffb00c1bc2fec 632 PRINTS PR00301 70kDa heat shock protein signature 3 16 7.3E-81 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 GBCGDNIH2_RS00110 030a7f738a318530350ffb00c1bc2fec 632 PRINTS PR00301 70kDa heat shock protein signature 54 62 7.3E-81 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 GBCGDNIH2_RS00110 030a7f738a318530350ffb00c1bc2fec 632 PRINTS PR00301 70kDa heat shock protein signature 138 158 7.3E-81 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 GBCGDNIH2_RS00110 030a7f738a318530350ffb00c1bc2fec 632 PRINTS PR00301 70kDa heat shock protein signature 383 402 7.3E-81 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 GBCGDNIH2_RS00110 030a7f738a318530350ffb00c1bc2fec 632 PRINTS PR00301 70kDa heat shock protein signature 197 207 7.3E-81 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 GBCGDNIH2_RS00110 030a7f738a318530350ffb00c1bc2fec 632 Gene3D G3DSA:3.30.420.40 1 195 4.2E-81 T 29-03-2018 GBCGDNIH2_RS05395 5350c3818d56f8c125ee2d9711c333a9 267 PIRSF PIRSF037208 2 250 4.9E-84 T 29-03-2018 IPR017138 Putative arginyl-tRNA--protein transferase, prokaryotic MetaCyc: PWY-7799 GBCGDNIH2_RS05395 5350c3818d56f8c125ee2d9711c333a9 267 Pfam PF04376 Arginine-tRNA-protein transferase, N terminus 19 89 3.2E-15 T 29-03-2018 IPR007471 Arginine-tRNA-protein transferase, N-terminal GO:0004057|GO:0016598 MetaCyc: PWY-7799 GBCGDNIH2_RS05395 5350c3818d56f8c125ee2d9711c333a9 267 Gene3D G3DSA:3.40.630.30 29 229 3.2E-6 T 29-03-2018 GBCGDNIH2_RS05395 5350c3818d56f8c125ee2d9711c333a9 267 Pfam PF04377 Arginine-tRNA-protein transferase, C terminus 109 231 6.6E-35 T 29-03-2018 IPR007472 Arginine-tRNA-protein transferase, C-terminal GO:0004057|GO:0016598 MetaCyc: PWY-7799 GBCGDNIH2_RS05395 5350c3818d56f8c125ee2d9711c333a9 267 Hamap MF_00689 Putative arginyl-tRNA--protein transferase [ate]. 2 240 42.538 T 29-03-2018 IPR017138 Putative arginyl-tRNA--protein transferase, prokaryotic MetaCyc: PWY-7799 GBCGDNIH2_RS05395 5350c3818d56f8c125ee2d9711c333a9 267 SUPERFAMILY SSF55729 86 239 9.28E-21 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase GBCGDNIH2_RS03715 f11b4890204e8981c91e740974c0bb63 578 Hamap MF_01810 Membrane protein insertase YidC [yidC]. 4 568 21.519 T 29-03-2018 IPR019998 Membrane insertase YidC GO:0016021|GO:0051205 GBCGDNIH2_RS03715 f11b4890204e8981c91e740974c0bb63 578 TIGRFAM TIGR03593 yidC_nterm: membrane protein insertase, YidC/Oxa1 family, N-terminal domain 3 364 1.6E-82 T 29-03-2018 IPR028053 Membrane insertase YidC, N-terminal GBCGDNIH2_RS03715 f11b4890204e8981c91e740974c0bb63 578 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 365 566 7.5E-69 T 29-03-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal GBCGDNIH2_RS03715 f11b4890204e8981c91e740974c0bb63 578 PRINTS PR00701 60kDa inner membrane protein signature 254 269 4.7E-15 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 GBCGDNIH2_RS03715 f11b4890204e8981c91e740974c0bb63 578 PRINTS PR00701 60kDa inner membrane protein signature 336 356 4.7E-15 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 GBCGDNIH2_RS03715 f11b4890204e8981c91e740974c0bb63 578 PRINTS PR00701 60kDa inner membrane protein signature 427 450 4.7E-15 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 GBCGDNIH2_RS03715 f11b4890204e8981c91e740974c0bb63 578 Pfam PF14849 YidC periplasmic domain 70 354 9.5E-78 T 29-03-2018 IPR028053 Membrane insertase YidC, N-terminal GBCGDNIH2_RS03715 f11b4890204e8981c91e740974c0bb63 578 PRINTS PR01900 YidC translocation/secretion protein signature 502 517 2.0E-22 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 GBCGDNIH2_RS03715 f11b4890204e8981c91e740974c0bb63 578 PRINTS PR01900 YidC translocation/secretion protein signature 521 545 2.0E-22 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 GBCGDNIH2_RS03715 f11b4890204e8981c91e740974c0bb63 578 PRINTS PR01900 YidC translocation/secretion protein signature 351 367 2.0E-22 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 GBCGDNIH2_RS03715 f11b4890204e8981c91e740974c0bb63 578 Pfam PF02096 60Kd inner membrane protein 366 566 2.4E-60 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 GBCGDNIH2_RS07385 9197b3c2d75b820284599bc8055f201e 351 Hamap MF_00268 Protein RecA [recA]. 9 334 52.71 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 GBCGDNIH2_RS07385 9197b3c2d75b820284599bc8055f201e 351 PRINTS PR00142 RecA protein signature 132 161 9.8E-86 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 GBCGDNIH2_RS07385 9197b3c2d75b820284599bc8055f201e 351 PRINTS PR00142 RecA protein signature 215 243 9.8E-86 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 GBCGDNIH2_RS07385 9197b3c2d75b820284599bc8055f201e 351 PRINTS PR00142 RecA protein signature 248 277 9.8E-86 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 GBCGDNIH2_RS07385 9197b3c2d75b820284599bc8055f201e 351 PRINTS PR00142 RecA protein signature 302 319 9.8E-86 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 GBCGDNIH2_RS07385 9197b3c2d75b820284599bc8055f201e 351 PRINTS PR00142 RecA protein signature 98 127 9.8E-86 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 GBCGDNIH2_RS07385 9197b3c2d75b820284599bc8055f201e 351 PRINTS PR00142 RecA protein signature 170 199 9.8E-86 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 GBCGDNIH2_RS07385 9197b3c2d75b820284599bc8055f201e 351 Pfam PF00154 recA bacterial DNA recombination protein 11 273 1.1E-145 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 GBCGDNIH2_RS07385 9197b3c2d75b820284599bc8055f201e 351 SUPERFAMILY SSF52540 9 272 1.76E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS07385 9197b3c2d75b820284599bc8055f201e 351 Gene3D G3DSA:3.30.250.10 274 330 5.2E-26 T 29-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal GBCGDNIH2_RS07385 9197b3c2d75b820284599bc8055f201e 351 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 8 329 6.9E-176 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 GBCGDNIH2_RS07385 9197b3c2d75b820284599bc8055f201e 351 Gene3D G3DSA:3.40.50.300 30 273 1.5E-47 T 29-03-2018 GBCGDNIH2_RS07385 9197b3c2d75b820284599bc8055f201e 351 ProSitePatterns PS00321 recA signature. 218 226 - T 29-03-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 GBCGDNIH2_RS07385 9197b3c2d75b820284599bc8055f201e 351 SUPERFAMILY SSF54752 273 330 5.62E-23 T 29-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal GBCGDNIH2_RS07385 9197b3c2d75b820284599bc8055f201e 351 SMART SM00382 62 233 1.7E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS09175 a12de42640eda3fa0162e963461a26fa 357 Gene3D G3DSA:3.40.190.10 135 325 9.0E-19 T 29-03-2018 GBCGDNIH2_RS09175 a12de42640eda3fa0162e963461a26fa 357 SUPERFAMILY SSF53850 37 251 1.51E-35 T 29-03-2018 GBCGDNIH2_RS09175 a12de42640eda3fa0162e963461a26fa 357 Pfam PF09084 NMT1/THI5 like 60 248 4.2E-10 T 29-03-2018 IPR015168 SsuA/THI5-like GBCGDNIH2_RS09175 a12de42640eda3fa0162e963461a26fa 357 TIGRFAM TIGR03427 ABC_peri_uca: ABC transporter periplasmic binding protein, urea carboxylase region 30 357 4.5E-166 T 29-03-2018 IPR017793 ABC transporter, urea utilisation-associated, substrate-binding protein GBCGDNIH2_RS09175 a12de42640eda3fa0162e963461a26fa 357 Gene3D G3DSA:3.40.190.10 27 134 1.5E-9 T 29-03-2018 GBCGDNIH2_RS00010 4e9981a01489740065b95b5da153f5cc 343 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 139 155 - T 29-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 GBCGDNIH2_RS00010 4e9981a01489740065b95b5da153f5cc 343 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 5 342 1.8E-118 T 29-03-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 GBCGDNIH2_RS00010 4e9981a01489740065b95b5da153f5cc 343 Gene3D G3DSA:3.20.20.210 1 343 6.2E-83 T 29-03-2018 GBCGDNIH2_RS00010 4e9981a01489740065b95b5da153f5cc 343 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 2 342 1.1E-112 T 29-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 GBCGDNIH2_RS00010 4e9981a01489740065b95b5da153f5cc 343 SUPERFAMILY SSF51726 2 343 1.12E-95 T 29-03-2018 GBCGDNIH2_RS00010 4e9981a01489740065b95b5da153f5cc 343 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 18 27 - T 29-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 GBCGDNIH2_RS00010 4e9981a01489740065b95b5da153f5cc 343 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 2 343 44.95 T 29-03-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 GBCGDNIH2_RS06940 315e7ae51a6d1c30395e51541e4a0629 339 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 213 226 - T 29-03-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS06940 315e7ae51a6d1c30395e51541e4a0629 339 Pfam PF00146 NADH dehydrogenase 19 326 6.8E-126 T 29-03-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS06940 315e7ae51a6d1c30395e51541e4a0629 339 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 12 332 24.571 T 29-03-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS02590 2fc86b6da93feeef98d124f33ace40e8 270 Gene3D G3DSA:3.90.226.10 2 236 2.9E-27 T 29-03-2018 GBCGDNIH2_RS02590 2fc86b6da93feeef98d124f33ace40e8 270 Pfam PF01343 Peptidase family S49 84 228 1.1E-28 T 29-03-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 GBCGDNIH2_RS02590 2fc86b6da93feeef98d124f33ace40e8 270 SUPERFAMILY SSF52096 159 220 5.24E-31 T 29-03-2018 IPR029045 ClpP/crotonase-like domain GBCGDNIH2_RS02590 2fc86b6da93feeef98d124f33ace40e8 270 SUPERFAMILY SSF52096 47 130 5.24E-31 T 29-03-2018 IPR029045 ClpP/crotonase-like domain GBCGDNIH2_RS07100 1eb822a2f968f0e74bd468d1268a1d4f 427 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 25 426 8.9E-167 T 29-03-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 GBCGDNIH2_RS07100 1eb822a2f968f0e74bd468d1268a1d4f 427 Gene3D G3DSA:3.90.1150.10 304 422 1.6E-41 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 GBCGDNIH2_RS07100 1eb822a2f968f0e74bd468d1268a1d4f 427 SUPERFAMILY SSF53383 21 423 2.06E-118 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase GBCGDNIH2_RS07100 1eb822a2f968f0e74bd468d1268a1d4f 427 Gene3D G3DSA:3.40.640.10 53 303 1.4E-56 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GBCGDNIH2_RS07100 1eb822a2f968f0e74bd468d1268a1d4f 427 Pfam PF00266 Aminotransferase class-V 43 414 6.3E-137 T 29-03-2018 IPR000192 Aminotransferase class V domain GBCGDNIH2_RS01015 8841a4370e005bca7876e3e0cd39ec5e 559 Pfam PF12848 ABC transporter 234 301 3.6E-12 T 29-03-2018 IPR032781 ABC-transporter extension domain GBCGDNIH2_RS01015 8841a4370e005bca7876e3e0cd39ec5e 559 Gene3D G3DSA:3.40.50.300 302 553 1.4E-55 T 29-03-2018 GBCGDNIH2_RS01015 8841a4370e005bca7876e3e0cd39ec5e 559 Gene3D G3DSA:3.40.50.300 6 301 1.6E-55 T 29-03-2018 GBCGDNIH2_RS01015 8841a4370e005bca7876e3e0cd39ec5e 559 SMART SM00382 33 244 3.0E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS01015 8841a4370e005bca7876e3e0cd39ec5e 559 SMART SM00382 352 528 7.8E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS01015 8841a4370e005bca7876e3e0cd39ec5e 559 SUPERFAMILY SSF52540 311 526 1.66E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS01015 8841a4370e005bca7876e3e0cd39ec5e 559 ProSitePatterns PS00211 ABC transporters family signature. 167 181 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GBCGDNIH2_RS01015 8841a4370e005bca7876e3e0cd39ec5e 559 SUPERFAMILY SSF52540 10 241 1.87E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS01015 8841a4370e005bca7876e3e0cd39ec5e 559 Pfam PF00005 ABC transporter 344 477 9.2E-24 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GBCGDNIH2_RS01015 8841a4370e005bca7876e3e0cd39ec5e 559 Pfam PF00005 ABC transporter 25 195 1.4E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GBCGDNIH2_RS01015 8841a4370e005bca7876e3e0cd39ec5e 559 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 5 557 7.2E-293 T 29-03-2018 IPR022374 ABC transporter, ATP-binding protein, ChvD GBCGDNIH2_RS09735 86dcf6b5fc006d25ba07915918bcf2d8 510 Pfam PF00854 POT family 85 451 8.6E-48 T 29-03-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 GBCGDNIH2_RS09735 86dcf6b5fc006d25ba07915918bcf2d8 510 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 14 492 7.6E-86 T 29-03-2018 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 GBCGDNIH2_RS09735 86dcf6b5fc006d25ba07915918bcf2d8 510 SUPERFAMILY SSF103473 11 303 7.98E-20 T 29-03-2018 IPR020846 Major facilitator superfamily domain GBCGDNIH2_RS09735 86dcf6b5fc006d25ba07915918bcf2d8 510 SUPERFAMILY SSF103473 315 496 6.54E-6 T 29-03-2018 IPR020846 Major facilitator superfamily domain GBCGDNIH2_RS09735 86dcf6b5fc006d25ba07915918bcf2d8 510 Gene3D G3DSA:1.20.1250.20 11 216 5.2E-23 T 29-03-2018 GBCGDNIH2_RS09735 86dcf6b5fc006d25ba07915918bcf2d8 510 Gene3D G3DSA:1.20.1250.20 271 498 2.1E-5 T 29-03-2018 GBCGDNIH2_RS07315 d1d5586630e17507a42e1e6d9a9c4175 404 SMART SM01329 9 395 6.7E-126 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 GBCGDNIH2_RS07315 d1d5586630e17507a42e1e6d9a9c4175 404 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 270 289 - T 29-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 GBCGDNIH2_RS07315 d1d5586630e17507a42e1e6d9a9c4175 404 Gene3D G3DSA:3.40.718.10 1 404 3.7E-126 T 29-03-2018 GBCGDNIH2_RS07315 d1d5586630e17507a42e1e6d9a9c4175 404 TIGRFAM TIGR00127 nadp_idh_euk: isocitrate dehydrogenase, NADP-dependent 3 403 1.2E-202 T 29-03-2018 IPR004790 Isocitrate dehydrogenase NADP-dependent GO:0004450|GO:0006102|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 GBCGDNIH2_RS07315 d1d5586630e17507a42e1e6d9a9c4175 404 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 7 379 9.7E-68 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 GBCGDNIH2_RS07315 d1d5586630e17507a42e1e6d9a9c4175 404 PIRSF PIRSF000108 1 404 2.5E-216 T 29-03-2018 IPR004790 Isocitrate dehydrogenase NADP-dependent GO:0004450|GO:0006102|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 GBCGDNIH2_RS07315 d1d5586630e17507a42e1e6d9a9c4175 404 SUPERFAMILY SSF53659 1 402 3.84E-147 T 29-03-2018 GBCGDNIH2_RS05240 82f55b342e6028c2c7c85856c1d689dd 154 PIRSF PIRSF002181 1 154 8.1E-46 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 GBCGDNIH2_RS05240 82f55b342e6028c2c7c85856c1d689dd 154 Gene3D G3DSA:3.90.1180.10 1 154 2.9E-53 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 GBCGDNIH2_RS05240 82f55b342e6028c2c7c85856c1d689dd 154 Pfam PF00572 Ribosomal protein L13 16 140 8.5E-50 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 GBCGDNIH2_RS05240 82f55b342e6028c2c7c85856c1d689dd 154 SUPERFAMILY SSF52161 7 144 1.7E-51 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 GBCGDNIH2_RS05240 82f55b342e6028c2c7c85856c1d689dd 154 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 16 143 26.437 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 GBCGDNIH2_RS05240 82f55b342e6028c2c7c85856c1d689dd 154 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 8 143 4.3E-56 T 29-03-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS01445 ce90dd203114defa59332715517e4ec0 919 SUPERFAMILY SSF50249 197 241 4.24E-15 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold GBCGDNIH2_RS01445 ce90dd203114defa59332715517e4ec0 919 SUPERFAMILY SSF50249 40 81 4.24E-15 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold GBCGDNIH2_RS01445 ce90dd203114defa59332715517e4ec0 919 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 14 546 1.2E-153 T 29-03-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 GBCGDNIH2_RS01445 ce90dd203114defa59332715517e4ec0 919 Gene3D G3DSA:2.40.50.140 33 240 1.2E-34 T 29-03-2018 GBCGDNIH2_RS01445 ce90dd203114defa59332715517e4ec0 919 Hamap MF_00970 Ribonuclease E [rne]. 2 919 28.478 T 29-03-2018 IPR028878 Ribonuclease E GO:0006396|GO:0008995 GBCGDNIH2_RS01445 ce90dd203114defa59332715517e4ec0 919 Pfam PF00575 S1 RNA binding domain 37 79 1.3E-4 T 29-03-2018 IPR003029 S1 domain GO:0003676 GBCGDNIH2_RS01445 ce90dd203114defa59332715517e4ec0 919 Pfam PF10150 Ribonuclease E/G family 237 512 1.3E-92 T 29-03-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 GBCGDNIH2_RS08710 fe43cf21f67f7a8bcdc9389f1b7b7598 267 Gene3D G3DSA:3.90.230.10 4 264 2.9E-83 T 29-03-2018 GBCGDNIH2_RS08710 fe43cf21f67f7a8bcdc9389f1b7b7598 267 SUPERFAMILY SSF55920 13 259 5.1E-86 T 29-03-2018 IPR000994 Peptidase M24 GBCGDNIH2_RS08710 fe43cf21f67f7a8bcdc9389f1b7b7598 267 Hamap MF_01974 Methionine aminopeptidase [map]. 10 256 40.835 T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 GBCGDNIH2_RS08710 fe43cf21f67f7a8bcdc9389f1b7b7598 267 PRINTS PR00599 Methionine aminopeptidase-1 signature 167 179 1.3E-22 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 GBCGDNIH2_RS08710 fe43cf21f67f7a8bcdc9389f1b7b7598 267 PRINTS PR00599 Methionine aminopeptidase-1 signature 97 113 1.3E-22 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 GBCGDNIH2_RS08710 fe43cf21f67f7a8bcdc9389f1b7b7598 267 PRINTS PR00599 Methionine aminopeptidase-1 signature 198 210 1.3E-22 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 GBCGDNIH2_RS08710 fe43cf21f67f7a8bcdc9389f1b7b7598 267 PRINTS PR00599 Methionine aminopeptidase-1 signature 75 88 1.3E-22 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 GBCGDNIH2_RS08710 fe43cf21f67f7a8bcdc9389f1b7b7598 267 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 173 191 - T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 GBCGDNIH2_RS08710 fe43cf21f67f7a8bcdc9389f1b7b7598 267 Pfam PF00557 Metallopeptidase family M24 21 247 4.2E-51 T 29-03-2018 IPR000994 Peptidase M24 GBCGDNIH2_RS08710 fe43cf21f67f7a8bcdc9389f1b7b7598 267 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 10 255 6.8E-93 T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 GBCGDNIH2_RS05700 3fdb8d9ea625135f682e499ed6e03ee4 378 SUPERFAMILY SSF51905 281 362 2.44E-48 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS05700 3fdb8d9ea625135f682e499ed6e03ee4 378 SUPERFAMILY SSF51905 5 167 2.44E-48 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS05700 3fdb8d9ea625135f682e499ed6e03ee4 378 Gene3D G3DSA:3.50.50.60 1 372 1.5E-39 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS05700 3fdb8d9ea625135f682e499ed6e03ee4 378 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 301 317 6.9E-19 T 29-03-2018 GBCGDNIH2_RS05700 3fdb8d9ea625135f682e499ed6e03ee4 378 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 146 161 6.9E-19 T 29-03-2018 GBCGDNIH2_RS05700 3fdb8d9ea625135f682e499ed6e03ee4 378 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 6.9E-19 T 29-03-2018 GBCGDNIH2_RS05700 3fdb8d9ea625135f682e499ed6e03ee4 378 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 286 301 6.9E-19 T 29-03-2018 GBCGDNIH2_RS05700 3fdb8d9ea625135f682e499ed6e03ee4 378 Pfam PF01494 FAD binding domain 5 162 2.0E-7 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 GBCGDNIH2_RS05700 3fdb8d9ea625135f682e499ed6e03ee4 378 Pfam PF01494 FAD binding domain 289 349 2.0E-8 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 GBCGDNIH2_RS02010 0f7322fa80e9e3ca3aa4a11d72b3635a 91 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 22 46 - T 29-03-2018 IPR001455 TusA-like domain GBCGDNIH2_RS02010 0f7322fa80e9e3ca3aa4a11d72b3635a 91 SUPERFAMILY SSF64307 9 90 1.44E-16 T 29-03-2018 IPR001455 TusA-like domain GBCGDNIH2_RS02010 0f7322fa80e9e3ca3aa4a11d72b3635a 91 Gene3D G3DSA:3.30.110.40 13 91 5.2E-15 T 29-03-2018 IPR001455 TusA-like domain GBCGDNIH2_RS02010 0f7322fa80e9e3ca3aa4a11d72b3635a 91 Pfam PF01206 Sulfurtransferase TusA 22 90 7.2E-17 T 29-03-2018 IPR001455 TusA-like domain GBCGDNIH2_RS09280 bb44c264aa31c2b02264ded785fd36ec 328 SUPERFAMILY SSF53474 89 324 1.49E-51 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS09280 bb44c264aa31c2b02264ded785fd36ec 328 Gene3D G3DSA:3.40.50.1820 34 328 4.5E-45 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS09280 bb44c264aa31c2b02264ded785fd36ec 328 Pfam PF07859 alpha/beta hydrolase fold 107 303 2.5E-52 T 29-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 GBCGDNIH2_RS09255 12532e6976eb390940de84d0471f9b77 299 Pfam PF03934 Type II secretion system (T2SS), protein K 46 202 2.4E-10 T 29-03-2018 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 GBCGDNIH2_RS09255 12532e6976eb390940de84d0471f9b77 299 Gene3D G3DSA:1.10.40.60 50 204 7.6E-11 T 29-03-2018 GBCGDNIH2_RS09255 12532e6976eb390940de84d0471f9b77 299 SUPERFAMILY SSF158544 107 201 3.66E-9 T 29-03-2018 GBCGDNIH2_RS08810 f9cdaf4d0bc2c733b02c24c5f9083c14 141 Gene3D G3DSA:1.10.10.10 1 137 4.1E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS08810 f9cdaf4d0bc2c733b02c24c5f9083c14 141 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 126 9.8E-34 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type GBCGDNIH2_RS08810 f9cdaf4d0bc2c733b02c24c5f9083c14 141 SUPERFAMILY SSF46785 2 128 1.36E-36 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS08810 f9cdaf4d0bc2c733b02c24c5f9083c14 141 Pfam PF02082 Transcriptional regulator 1 80 1.3E-24 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type GBCGDNIH2_RS05995 15ab61038f446d25483a5c0a668a5c1c 433 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 40 219 7.0E-41 T 29-03-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 GBCGDNIH2_RS05995 15ab61038f446d25483a5c0a668a5c1c 433 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 26 274 17.319 T 29-03-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 GBCGDNIH2_RS05995 15ab61038f446d25483a5c0a668a5c1c 433 Gene3D G3DSA:3.40.50.620 37 257 1.1E-31 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GBCGDNIH2_RS05995 15ab61038f446d25483a5c0a668a5c1c 433 SUPERFAMILY SSF52402 39 221 1.15E-41 T 29-03-2018 GBCGDNIH2_RS05995 15ab61038f446d25483a5c0a668a5c1c 433 Pfam PF01171 PP-loop family 41 218 2.1E-43 T 29-03-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 GBCGDNIH2_RS11725 7512e37341cb494286e1f21640774d86 207 Gene3D G3DSA:3.90.1720.10 47 159 5.1E-4 T 29-03-2018 GBCGDNIH2_RS11725 7512e37341cb494286e1f21640774d86 207 Pfam PF05257 CHAP domain 63 137 1.1E-9 T 29-03-2018 IPR007921 CHAP domain GBCGDNIH2_RS11725 7512e37341cb494286e1f21640774d86 207 SUPERFAMILY SSF54001 58 184 6.77E-27 T 29-03-2018 GBCGDNIH2_RS10305 d2bade8da57ae754b2a4ef6addf88475 233 Pfam PF00072 Response regulator receiver domain 5 114 1.4E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GBCGDNIH2_RS10305 d2bade8da57ae754b2a4ef6addf88475 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 229 4.4E-21 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 GBCGDNIH2_RS10305 d2bade8da57ae754b2a4ef6addf88475 233 SUPERFAMILY SSF52172 3 121 1.31E-38 T 29-03-2018 IPR011006 CheY-like superfamily GBCGDNIH2_RS10305 d2bade8da57ae754b2a4ef6addf88475 233 SUPERFAMILY SSF46894 136 230 4.82E-25 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 GBCGDNIH2_RS10305 d2bade8da57ae754b2a4ef6addf88475 233 SMART SM00448 3 113 7.7E-40 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GBCGDNIH2_RS10305 d2bade8da57ae754b2a4ef6addf88475 233 Gene3D G3DSA:1.10.10.10 125 233 1.0E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS10305 d2bade8da57ae754b2a4ef6addf88475 233 Gene3D G3DSA:3.40.50.2300 2 124 6.5E-37 T 29-03-2018 GBCGDNIH2_RS10305 d2bade8da57ae754b2a4ef6addf88475 233 SMART SM00862 154 230 8.1E-19 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 GBCGDNIH2_RS12720 61d84ae71a1313281a7547504d4d1423 298 PRINTS PR00126 ATP synthase gamma subunit signature 276 297 1.7E-33 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 GBCGDNIH2_RS12720 61d84ae71a1313281a7547504d4d1423 298 PRINTS PR00126 ATP synthase gamma subunit signature 171 188 1.7E-33 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 GBCGDNIH2_RS12720 61d84ae71a1313281a7547504d4d1423 298 PRINTS PR00126 ATP synthase gamma subunit signature 245 264 1.7E-33 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 GBCGDNIH2_RS12720 61d84ae71a1313281a7547504d4d1423 298 PRINTS PR00126 ATP synthase gamma subunit signature 76 95 1.7E-33 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 GBCGDNIH2_RS12720 61d84ae71a1313281a7547504d4d1423 298 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 1 298 6.2E-102 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 GBCGDNIH2_RS12720 61d84ae71a1313281a7547504d4d1423 298 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 298 33.165 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 GBCGDNIH2_RS12720 61d84ae71a1313281a7547504d4d1423 298 Gene3D G3DSA:1.10.287.80 184 279 6.0E-30 T 29-03-2018 GBCGDNIH2_RS12720 61d84ae71a1313281a7547504d4d1423 298 PIRSF PIRSF039089 1 298 7.4E-103 T 29-03-2018 GBCGDNIH2_RS12720 61d84ae71a1313281a7547504d4d1423 298 Gene3D G3DSA:3.40.1380.10 68 183 1.6E-31 T 29-03-2018 GBCGDNIH2_RS12720 61d84ae71a1313281a7547504d4d1423 298 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 284 297 - T 29-03-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 GBCGDNIH2_RS12720 61d84ae71a1313281a7547504d4d1423 298 Pfam PF00231 ATP synthase 3 298 5.6E-96 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 GBCGDNIH2_RS12720 61d84ae71a1313281a7547504d4d1423 298 Gene3D G3DSA:1.10.287.80 2 58 1.2E-18 T 29-03-2018 GBCGDNIH2_RS12720 61d84ae71a1313281a7547504d4d1423 298 SUPERFAMILY SSF52943 2 298 2.49E-87 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 GBCGDNIH2_RS08390 9dbc04fea9995d7b37bfbe06c2e0a6ce 266 Gene3D G3DSA:1.10.760.10 167 266 3.4E-15 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 GBCGDNIH2_RS08390 9dbc04fea9995d7b37bfbe06c2e0a6ce 266 Gene3D G3DSA:3.90.420.10 7 166 7.5E-5 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 GBCGDNIH2_RS08390 9dbc04fea9995d7b37bfbe06c2e0a6ce 266 SUPERFAMILY SSF46626 159 266 8.61E-16 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 GBCGDNIH2_RS08390 9dbc04fea9995d7b37bfbe06c2e0a6ce 266 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 180 263 1.3E-8 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 GBCGDNIH2_RS04130 4919de0252948b3d2f40c58ca16e6b08 812 Pfam PF00575 S1 RNA binding domain 693 736 2.2E-6 T 29-03-2018 IPR003029 S1 domain GO:0003676 GBCGDNIH2_RS04130 4919de0252948b3d2f40c58ca16e6b08 812 ProSitePatterns PS01175 Ribonuclease II family signature. 614 638 - T 29-03-2018 IPR022966 Ribonuclease II/R, conserved site GBCGDNIH2_RS04130 4919de0252948b3d2f40c58ca16e6b08 812 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 236 769 3.5E-141 T 29-03-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 GBCGDNIH2_RS04130 4919de0252948b3d2f40c58ca16e6b08 812 Pfam PF00773 RNB domain 329 645 2.9E-94 T 29-03-2018 GBCGDNIH2_RS04130 4919de0252948b3d2f40c58ca16e6b08 812 SUPERFAMILY SSF50249 693 775 3.43E-15 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold GBCGDNIH2_RS04130 4919de0252948b3d2f40c58ca16e6b08 812 Gene3D G3DSA:2.40.50.140 692 776 1.4E-9 T 29-03-2018 GBCGDNIH2_RS04130 4919de0252948b3d2f40c58ca16e6b08 812 SMART SM00316 693 776 0.0056 T 29-03-2018 IPR022967 RNA-binding domain, S1 GBCGDNIH2_RS04130 4919de0252948b3d2f40c58ca16e6b08 812 SMART SM00955 329 647 9.9E-156 T 29-03-2018 GBCGDNIH2_RS04130 4919de0252948b3d2f40c58ca16e6b08 812 TIGRFAM TIGR02063 RNase_R: ribonuclease R 44 776 2.0E-187 T 29-03-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 GBCGDNIH2_RS04130 4919de0252948b3d2f40c58ca16e6b08 812 Hamap MF_01895 Ribonuclease R [rnr]. 63 776 53.221 T 29-03-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 GBCGDNIH2_RS04130 4919de0252948b3d2f40c58ca16e6b08 812 SUPERFAMILY SSF50249 299 693 1.63E-132 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold GBCGDNIH2_RS09235 7d482c1637d0f280b5ff791e29b3deb0 212 Pfam PF10741 Type II secretion system (T2SS), protein M subtype b 89 201 2.7E-28 T 29-03-2018 IPR034756 Type II secretion system (T2SS), protein M subtype b GBCGDNIH2_RS09235 7d482c1637d0f280b5ff791e29b3deb0 212 Gene3D G3DSA:3.30.70.60 98 211 7.5E-7 T 29-03-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 GBCGDNIH2_RS10985 3f6fa8ec600e9d51d4434b2a05fb44fe 448 Gene3D G3DSA:3.20.20.70 19 439 5.5E-84 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS10985 3f6fa8ec600e9d51d4434b2a05fb44fe 448 PIRSF PIRSF500061 7 446 1.4E-164 T 29-03-2018 GBCGDNIH2_RS10985 3f6fa8ec600e9d51d4434b2a05fb44fe 448 Pfam PF01645 Conserved region in glutamate synthase 86 338 1.7E-77 T 29-03-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 GBCGDNIH2_RS10985 3f6fa8ec600e9d51d4434b2a05fb44fe 448 SUPERFAMILY SSF51395 16 431 6.96E-87 T 29-03-2018 GBCGDNIH2_RS10985 3f6fa8ec600e9d51d4434b2a05fb44fe 448 PIRSF PIRSF006429 6 447 2.2E-147 T 29-03-2018 IPR024188 Glutamate synthase large subunit-like protein GBCGDNIH2_RS06065 b85b4065f12b156ef5173740db34ecc2 288 SUPERFAMILY SSF56752 3 279 1.12E-67 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 GBCGDNIH2_RS06065 b85b4065f12b156ef5173740db34ecc2 288 Gene3D G3DSA:3.20.10.10 136 287 7.7E-37 T 29-03-2018 GBCGDNIH2_RS06065 b85b4065f12b156ef5173740db34ecc2 288 Gene3D G3DSA:3.30.470.10 1 135 7.2E-28 T 29-03-2018 GBCGDNIH2_RS06065 b85b4065f12b156ef5173740db34ecc2 288 Pfam PF01063 Amino-transferase class IV 32 257 2.2E-42 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 GBCGDNIH2_RS02485 2c3405e7da02c5d11bb02a59a11f886a 214 Pfam PF08511 COQ9 117 192 2.4E-24 T 29-03-2018 IPR013718 COQ9 Reactome: R-HSA-2142789 GBCGDNIH2_RS02485 2c3405e7da02c5d11bb02a59a11f886a 214 TIGRFAM TIGR02396 diverge_rpsU: rpsU-divergently transcribed protein 15 196 2.4E-41 T 29-03-2018 IPR012762 Ubiquinone biosynthesis protein COQ9 GO:0006744 Reactome: R-HSA-2142789 GBCGDNIH2_RS00950 05e7b233ba92819da51b60cbde9ef045 125 Gene3D G3DSA:3.40.30.10 1 125 3.9E-31 T 29-03-2018 GBCGDNIH2_RS00950 05e7b233ba92819da51b60cbde9ef045 125 SUPERFAMILY SSF52833 2 116 5.79E-31 T 29-03-2018 IPR012336 Thioredoxin-like fold GBCGDNIH2_RS00950 05e7b233ba92819da51b60cbde9ef045 125 Pfam PF03960 ArsC family 6 112 5.7E-15 T 29-03-2018 IPR006660 Arsenate reductase-like GBCGDNIH2_RS00950 05e7b233ba92819da51b60cbde9ef045 125 TIGRFAM TIGR00014 arsC: arsenate reductase (glutaredoxin) 3 115 1.7E-33 T 29-03-2018 IPR006659 Arsenate reductase GO:0008794|GO:0055114 MetaCyc: PWY-4202|MetaCyc: PWY-4621 GBCGDNIH2_RS00235 478e54341114f1eed4efcd2ff297f354 572 Hamap MF_01543 Formate--tetrahydrofolate ligase [fhs]. 16 572 48.807 T 29-03-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 GBCGDNIH2_RS00235 478e54341114f1eed4efcd2ff297f354 572 Gene3D G3DSA:3.10.410.10 460 548 8.1E-35 T 29-03-2018 GBCGDNIH2_RS00235 478e54341114f1eed4efcd2ff297f354 572 ProSitePatterns PS00722 Formate--tetrahydrofolate ligase signature 2. 344 355 - T 29-03-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 GBCGDNIH2_RS00235 478e54341114f1eed4efcd2ff297f354 572 Pfam PF01268 Formate--tetrahydrofolate ligase 17 572 4.6E-268 T 29-03-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 GBCGDNIH2_RS00235 478e54341114f1eed4efcd2ff297f354 572 Gene3D G3DSA:3.40.50.300 27 248 8.6E-97 T 29-03-2018 GBCGDNIH2_RS00235 478e54341114f1eed4efcd2ff297f354 572 Gene3D G3DSA:3.40.50.300 249 458 6.0E-78 T 29-03-2018 GBCGDNIH2_RS00235 478e54341114f1eed4efcd2ff297f354 572 ProSitePatterns PS00721 Formate--tetrahydrofolate ligase signature 1. 119 129 - T 29-03-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 GBCGDNIH2_RS00235 478e54341114f1eed4efcd2ff297f354 572 SUPERFAMILY SSF52540 19 570 1.33E-246 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS00365 fbe82e9f7425dfc3b93d44660510e28d 654 Gene3D G3DSA:1.10.1060.10 220 360 4.7E-25 T 29-03-2018 GBCGDNIH2_RS00365 fbe82e9f7425dfc3b93d44660510e28d 654 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 325 336 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site GBCGDNIH2_RS00365 fbe82e9f7425dfc3b93d44660510e28d 654 Pfam PF02754 Cysteine-rich domain 417 484 8.1E-5 T 29-03-2018 IPR004017 Cysteine-rich domain GBCGDNIH2_RS00365 fbe82e9f7425dfc3b93d44660510e28d 654 Pfam PF02754 Cysteine-rich domain 527 613 3.6E-14 T 29-03-2018 IPR004017 Cysteine-rich domain GBCGDNIH2_RS00365 fbe82e9f7425dfc3b93d44660510e28d 654 SUPERFAMILY SSF46548 235 352 3.14E-20 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 GBCGDNIH2_RS00365 fbe82e9f7425dfc3b93d44660510e28d 654 Pfam PF13187 4Fe-4S dicluster domain 250 337 2.5E-10 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain GBCGDNIH2_RS00365 fbe82e9f7425dfc3b93d44660510e28d 654 Pfam PF11982 Domain of unknown function (DUF3483) 6 229 5.3E-71 T 29-03-2018 IPR021872 Protein of unknown function DUF3483 GBCGDNIH2_RS03215 341c458e9d7ce9f7bf27a2f8f0e1ff1c 344 Gene3D G3DSA:3.40.50.300 69 329 1.1E-17 T 29-03-2018 GBCGDNIH2_RS03215 341c458e9d7ce9f7bf27a2f8f0e1ff1c 344 Pfam PF07728 AAA domain (dynein-related subfamily) 81 203 2.9E-12 T 29-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 GBCGDNIH2_RS03215 341c458e9d7ce9f7bf27a2f8f0e1ff1c 344 TIGRFAM TIGR01650 PD_CobS: cobaltochelatase, CobS subunit 24 336 4.6E-177 T 29-03-2018 IPR006537 Cobaltochelatase subunit CobS KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 GBCGDNIH2_RS03215 341c458e9d7ce9f7bf27a2f8f0e1ff1c 344 SMART SM00382 77 223 0.005 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS03215 341c458e9d7ce9f7bf27a2f8f0e1ff1c 344 Pfam PF12556 Cobaltochelatase CobS subunit N terminal 22 54 1.4E-17 T 29-03-2018 IPR025865 Cobaltochelatase subunit CobS N-terminal domain KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 GBCGDNIH2_RS03215 341c458e9d7ce9f7bf27a2f8f0e1ff1c 344 SUPERFAMILY SSF52540 70 304 6.11E-30 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS07455 24d000da27c5390b3c51e9a63b3e045f 362 PIRSF PIRSF004532 47 361 4.4E-136 T 29-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 GBCGDNIH2_RS07455 24d000da27c5390b3c51e9a63b3e045f 362 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 49 355 7.7E-140 T 29-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 GBCGDNIH2_RS07455 24d000da27c5390b3c51e9a63b3e045f 362 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 49 359 8.6E-112 T 29-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 GBCGDNIH2_RS07455 24d000da27c5390b3c51e9a63b3e045f 362 Gene3D G3DSA:3.30.540.10 45 197 5.1E-54 T 29-03-2018 GBCGDNIH2_RS07455 24d000da27c5390b3c51e9a63b3e045f 362 Gene3D G3DSA:3.30.540.10 198 362 1.3E-54 T 29-03-2018 GBCGDNIH2_RS07455 24d000da27c5390b3c51e9a63b3e045f 362 SUPERFAMILY SSF56655 46 358 1.19E-107 T 29-03-2018 GBCGDNIH2_RS04150 55df54e39abb9ae82b5a2050519a42fe 429 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 28 427 6.8E-104 T 29-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 GBCGDNIH2_RS04150 55df54e39abb9ae82b5a2050519a42fe 429 Gene3D G3DSA:2.30.40.10 6 76 3.9E-18 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 GBCGDNIH2_RS04150 55df54e39abb9ae82b5a2050519a42fe 429 Hamap MF_00220_B Dihydroorotase [pyrC]. 8 429 34.409 T 29-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 GBCGDNIH2_RS04150 55df54e39abb9ae82b5a2050519a42fe 429 Gene3D G3DSA:3.20.20.140 77 394 2.6E-83 T 29-03-2018 GBCGDNIH2_RS04150 55df54e39abb9ae82b5a2050519a42fe 429 SUPERFAMILY SSF51338 7 61 1.3E-24 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 GBCGDNIH2_RS04150 55df54e39abb9ae82b5a2050519a42fe 429 SUPERFAMILY SSF51338 373 428 1.3E-24 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 GBCGDNIH2_RS04150 55df54e39abb9ae82b5a2050519a42fe 429 Pfam PF01979 Amidohydrolase family 59 427 1.7E-21 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 GBCGDNIH2_RS04150 55df54e39abb9ae82b5a2050519a42fe 429 SUPERFAMILY SSF51556 62 373 4.43E-90 T 29-03-2018 IPR032466 Metal-dependent hydrolase GBCGDNIH2_RS08775 a7944828dbd301deb7913b5109bd103e 254 Gene3D G3DSA:3.30.470.20 94 224 2.5E-46 T 29-03-2018 GBCGDNIH2_RS08775 a7944828dbd301deb7913b5109bd103e 254 SUPERFAMILY SSF56104 4 236 1.44E-77 T 29-03-2018 GBCGDNIH2_RS08775 a7944828dbd301deb7913b5109bd103e 254 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 4 238 31.796 T 29-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 GBCGDNIH2_RS08775 a7944828dbd301deb7913b5109bd103e 254 Gene3D G3DSA:3.30.200.20 1 93 1.4E-24 T 29-03-2018 GBCGDNIH2_RS08775 a7944828dbd301deb7913b5109bd103e 254 Pfam PF01259 SAICAR synthetase 7 235 1.9E-61 T 29-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 GBCGDNIH2_RS08775 a7944828dbd301deb7913b5109bd103e 254 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 4 237 4.9E-65 T 29-03-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 GBCGDNIH2_RS08775 a7944828dbd301deb7913b5109bd103e 254 ProSitePatterns PS01058 SAICAR synthetase signature 2. 173 181 - T 29-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 GBCGDNIH2_RS08775 a7944828dbd301deb7913b5109bd103e 254 ProSitePatterns PS01057 SAICAR synthetase signature 1. 86 100 - T 29-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 GBCGDNIH2_RS02360 fec409f3e8a6869147da665f2dc39254 251 SUPERFAMILY SSF55120 76 240 2.73E-36 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 GBCGDNIH2_RS02360 fec409f3e8a6869147da665f2dc39254 251 SUPERFAMILY SSF55174 14 76 1.31E-14 T 29-03-2018 GBCGDNIH2_RS02360 fec409f3e8a6869147da665f2dc39254 251 Gene3D G3DSA:3.10.290.10 14 77 5.0E-17 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 GBCGDNIH2_RS02360 fec409f3e8a6869147da665f2dc39254 251 Pfam PF00849 RNA pseudouridylate synthase 85 209 1.5E-9 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 GBCGDNIH2_RS02360 fec409f3e8a6869147da665f2dc39254 251 Pfam PF01479 S4 domain 17 63 4.2E-14 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 GBCGDNIH2_RS02360 fec409f3e8a6869147da665f2dc39254 251 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 115 129 - T 29-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 GBCGDNIH2_RS02360 fec409f3e8a6869147da665f2dc39254 251 SMART SM00363 17 77 1.4E-12 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 GBCGDNIH2_RS02360 fec409f3e8a6869147da665f2dc39254 251 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 82 240 4.3E-41 T 29-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 GBCGDNIH2_RS02360 fec409f3e8a6869147da665f2dc39254 251 Gene3D G3DSA:3.30.70.1560 161 222 9.4E-17 T 29-03-2018 GBCGDNIH2_RS02360 fec409f3e8a6869147da665f2dc39254 251 Gene3D G3DSA:3.30.70.580 78 160 2.3E-15 T 29-03-2018 GBCGDNIH2_RS02140 a221c18bbe84dea1f4238f9d78efea49 963 Hamap MF_00277 Bifunctional uridylyltransferase/uridylyl-removing enzyme [glnD]. 45 950 262.486 T 29-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 GBCGDNIH2_RS02140 a221c18bbe84dea1f4238f9d78efea49 963 Gene3D G3DSA:3.30.70.260 858 942 1.2E-14 T 29-03-2018 GBCGDNIH2_RS02140 a221c18bbe84dea1f4238f9d78efea49 963 SUPERFAMILY SSF81301 50 214 5.61E-25 T 29-03-2018 GBCGDNIH2_RS02140 a221c18bbe84dea1f4238f9d78efea49 963 Pfam PF01966 HD domain 520 631 1.7E-9 T 29-03-2018 IPR006674 HD domain GBCGDNIH2_RS02140 a221c18bbe84dea1f4238f9d78efea49 963 SUPERFAMILY SSF55021 865 934 9.58E-12 T 29-03-2018 GBCGDNIH2_RS02140 a221c18bbe84dea1f4238f9d78efea49 963 SUPERFAMILY SSF81593 245 364 3.53E-9 T 29-03-2018 GBCGDNIH2_RS02140 a221c18bbe84dea1f4238f9d78efea49 963 SUPERFAMILY SSF55021 754 810 7.5E-11 T 29-03-2018 GBCGDNIH2_RS02140 a221c18bbe84dea1f4238f9d78efea49 963 SUPERFAMILY SSF109604 483 631 1.04E-13 T 29-03-2018 GBCGDNIH2_RS02140 a221c18bbe84dea1f4238f9d78efea49 963 Gene3D G3DSA:3.30.460.10 9 219 1.7E-18 T 29-03-2018 GBCGDNIH2_RS02140 a221c18bbe84dea1f4238f9d78efea49 963 TIGRFAM TIGR01693 UTase_glnD: protein-P-II uridylyltransferase 79 937 2.5E-250 T 29-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 GBCGDNIH2_RS02140 a221c18bbe84dea1f4238f9d78efea49 963 PIRSF PIRSF006288 45 945 1.5E-300 T 29-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 GBCGDNIH2_RS02140 a221c18bbe84dea1f4238f9d78efea49 963 Gene3D G3DSA:1.10.3090.10 401 708 2.7E-39 T 29-03-2018 GBCGDNIH2_RS02140 a221c18bbe84dea1f4238f9d78efea49 963 Gene3D G3DSA:3.30.70.260 750 842 2.0E-13 T 29-03-2018 GBCGDNIH2_RS02140 a221c18bbe84dea1f4238f9d78efea49 963 Pfam PF08335 GlnD PII-uridylyltransferase 225 368 5.8E-36 T 29-03-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 GBCGDNIH2_RS02140 a221c18bbe84dea1f4238f9d78efea49 963 Gene3D G3DSA:1.20.120.330 224 369 4.9E-23 T 29-03-2018 GBCGDNIH2_RS03410 4764df1a3f6d7ce75eaca7039db6ff48 358 SUPERFAMILY SSF55961 151 350 1.95E-23 T 29-03-2018 GBCGDNIH2_RS03410 4764df1a3f6d7ce75eaca7039db6ff48 358 Gene3D G3DSA:2.102.10.10 36 139 5.6E-23 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 GBCGDNIH2_RS03410 4764df1a3f6d7ce75eaca7039db6ff48 358 SUPERFAMILY SSF50022 29 146 2.62E-31 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 GBCGDNIH2_RS03410 4764df1a3f6d7ce75eaca7039db6ff48 358 Pfam PF00355 Rieske [2Fe-2S] domain 39 118 3.4E-17 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 GBCGDNIH2_RS03410 4764df1a3f6d7ce75eaca7039db6ff48 358 Gene3D G3DSA:3.90.380.10 140 351 1.3E-41 T 29-03-2018 GBCGDNIH2_RS06625 ea175497f0ab24c730f774453a1a4143 41 Pfam PF00444 Ribosomal protein L36 1 41 2.1E-17 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS06625 ea175497f0ab24c730f774453a1a4143 41 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 41 7.1E-8 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS06625 ea175497f0ab24c730f774453a1a4143 41 SUPERFAMILY SSF57840 1 41 4.97E-13 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS06625 ea175497f0ab24c730f774453a1a4143 41 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 41 17.47 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS05090 5db04f3464d7ed2f4e69c5f6633b2a34 241 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 7 237 7.9E-101 T 29-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 GBCGDNIH2_RS05090 5db04f3464d7ed2f4e69c5f6633b2a34 241 Gene3D G3DSA:3.40.1160.10 1 239 2.7E-42 T 29-03-2018 GBCGDNIH2_RS05090 5db04f3464d7ed2f4e69c5f6633b2a34 241 Pfam PF00696 Amino acid kinase family 8 217 6.0E-29 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase GBCGDNIH2_RS05090 5db04f3464d7ed2f4e69c5f6633b2a34 241 SUPERFAMILY SSF53633 5 238 1.15E-70 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase GBCGDNIH2_RS05090 5db04f3464d7ed2f4e69c5f6633b2a34 241 Hamap MF_01220_B Uridylate kinase [pyrH]. 5 238 44.538 T 29-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 GBCGDNIH2_RS05090 5db04f3464d7ed2f4e69c5f6633b2a34 241 PIRSF PIRSF005650 2 241 1.8E-94 T 29-03-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 GBCGDNIH2_RS06320 09bc4d4f70952c3de4967c477c77d0c2 294 Gene3D G3DSA:3.40.710.10 29 294 3.8E-33 T 29-03-2018 GBCGDNIH2_RS06320 09bc4d4f70952c3de4967c477c77d0c2 294 ProSitePatterns PS00146 Beta-lactamase class-A active site. 71 86 - T 29-03-2018 IPR023650 Beta-lactamase, class-A active site KEGG: 00311+3.5.2.6 GBCGDNIH2_RS06320 09bc4d4f70952c3de4967c477c77d0c2 294 SUPERFAMILY SSF56601 35 291 7.45E-64 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like GBCGDNIH2_RS06320 09bc4d4f70952c3de4967c477c77d0c2 294 PRINTS PR00118 Beta-lactamase class A signature 38 62 2.2E-50 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 GBCGDNIH2_RS06320 09bc4d4f70952c3de4967c477c77d0c2 294 PRINTS PR00118 Beta-lactamase class A signature 69 86 2.2E-50 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 GBCGDNIH2_RS06320 09bc4d4f70952c3de4967c477c77d0c2 294 PRINTS PR00118 Beta-lactamase class A signature 173 198 2.2E-50 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 GBCGDNIH2_RS06320 09bc4d4f70952c3de4967c477c77d0c2 294 PRINTS PR00118 Beta-lactamase class A signature 227 242 2.2E-50 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 GBCGDNIH2_RS06320 09bc4d4f70952c3de4967c477c77d0c2 294 PRINTS PR00118 Beta-lactamase class A signature 147 171 2.2E-50 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 GBCGDNIH2_RS06320 09bc4d4f70952c3de4967c477c77d0c2 294 PRINTS PR00118 Beta-lactamase class A signature 111 136 2.2E-50 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 GBCGDNIH2_RS06320 09bc4d4f70952c3de4967c477c77d0c2 294 Pfam PF13354 Beta-lactamase enzyme family 59 266 2.9E-35 T 29-03-2018 GBCGDNIH2_RS00285 69e4a805152270ca8b64570b2924d538 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 186 203 2.9E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS00285 69e4a805152270ca8b64570b2924d538 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 2.9E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS00285 69e4a805152270ca8b64570b2924d538 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 18 35 2.9E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS00285 69e4a805152270ca8b64570b2924d538 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 2.9E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS00285 69e4a805152270ca8b64570b2924d538 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 155 2.9E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS00285 69e4a805152270ca8b64570b2924d538 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 184 2.9E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS00285 69e4a805152270ca8b64570b2924d538 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 17 201 1.0E-4 T 29-03-2018 GBCGDNIH2_RS00285 69e4a805152270ca8b64570b2924d538 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 165 184 7.8E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS00285 69e4a805152270ca8b64570b2924d538 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 92 103 7.8E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS00285 69e4a805152270ca8b64570b2924d538 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 153 7.8E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS00285 69e4a805152270ca8b64570b2924d538 253 SUPERFAMILY SSF51735 19 252 5.75E-69 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS00285 69e4a805152270ca8b64570b2924d538 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 25 252 1.6E-52 T 29-03-2018 GBCGDNIH2_RS00285 69e4a805152270ca8b64570b2924d538 253 Gene3D G3DSA:3.40.50.720 17 253 7.7E-62 T 29-03-2018 GBCGDNIH2_RS02355 d4491797993aa825b3358f7cefe7c2cb 240 Pfam PF07722 Peptidase C26 7 220 7.9E-60 T 29-03-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 GBCGDNIH2_RS02355 d4491797993aa825b3358f7cefe7c2cb 240 Gene3D G3DSA:3.40.50.880 3 240 1.8E-44 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like GBCGDNIH2_RS02355 d4491797993aa825b3358f7cefe7c2cb 240 SUPERFAMILY SSF52317 26 238 3.21E-42 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like GBCGDNIH2_RS05840 36d2de8db3fba4f82ca095ed2258fe17 262 SUPERFAMILY SSF56281 1 258 1.83E-47 T 29-03-2018 IPR001279 Metallo-beta-lactamase GBCGDNIH2_RS05840 36d2de8db3fba4f82ca095ed2258fe17 262 Gene3D G3DSA:3.60.15.10 1 260 2.4E-46 T 29-03-2018 IPR001279 Metallo-beta-lactamase GBCGDNIH2_RS05840 36d2de8db3fba4f82ca095ed2258fe17 262 SMART SM00849 39 231 1.1E-9 T 29-03-2018 IPR001279 Metallo-beta-lactamase GBCGDNIH2_RS05840 36d2de8db3fba4f82ca095ed2258fe17 262 Pfam PF12706 Beta-lactamase superfamily domain 50 232 6.9E-36 T 29-03-2018 IPR001279 Metallo-beta-lactamase GBCGDNIH2_RS02920 627940ad0af41417ead30155f703071d 190 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 172 35.465 T 29-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 GBCGDNIH2_RS02920 627940ad0af41417ead30155f703071d 190 Pfam PF03719 Ribosomal protein S5, C-terminal domain 96 166 2.3E-28 T 29-03-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 GBCGDNIH2_RS02920 627940ad0af41417ead30155f703071d 190 Gene3D G3DSA:3.30.160.20 18 80 7.3E-27 T 29-03-2018 GBCGDNIH2_RS02920 627940ad0af41417ead30155f703071d 190 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 18 172 8.1E-65 T 29-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 GBCGDNIH2_RS02920 627940ad0af41417ead30155f703071d 190 SUPERFAMILY SSF54768 16 84 6.07E-23 T 29-03-2018 GBCGDNIH2_RS02920 627940ad0af41417ead30155f703071d 190 SUPERFAMILY SSF54211 88 168 2.78E-25 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold GBCGDNIH2_RS02920 627940ad0af41417ead30155f703071d 190 ProSitePatterns PS00585 Ribosomal protein S5 signature. 36 68 - T 29-03-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site GBCGDNIH2_RS02920 627940ad0af41417ead30155f703071d 190 Pfam PF00333 Ribosomal protein S5, N-terminal domain 21 83 1.1E-28 T 29-03-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 GBCGDNIH2_RS02920 627940ad0af41417ead30155f703071d 190 Gene3D G3DSA:3.30.230.10 85 175 1.0E-31 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup GBCGDNIH2_RS02725 dd936fcd5673a6e8865fb9f2c8bc64e1 249 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 54 222 8.7E-35 T 29-03-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 GBCGDNIH2_RS02725 dd936fcd5673a6e8865fb9f2c8bc64e1 249 PIRSF PIRSF000857 8 249 1.4E-75 T 29-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 GBCGDNIH2_RS02725 dd936fcd5673a6e8865fb9f2c8bc64e1 249 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 47 246 2.2E-49 T 29-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 GBCGDNIH2_RS02725 dd936fcd5673a6e8865fb9f2c8bc64e1 249 SUPERFAMILY SSF52402 46 210 5.79E-42 T 29-03-2018 GBCGDNIH2_RS02725 dd936fcd5673a6e8865fb9f2c8bc64e1 249 Gene3D G3DSA:3.40.50.620 2 249 5.5E-33 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GBCGDNIH2_RS12580 b0200a773f9e16dcd874f9610acced7e 215 SMART SM00478 38 185 6.9E-50 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 GBCGDNIH2_RS12580 b0200a773f9e16dcd874f9610acced7e 215 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 34 163 7.7E-18 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 GBCGDNIH2_RS12580 b0200a773f9e16dcd874f9610acced7e 215 Gene3D G3DSA:1.10.340.30 19 117 1.5E-25 T 29-03-2018 GBCGDNIH2_RS12580 b0200a773f9e16dcd874f9610acced7e 215 SUPERFAMILY SSF48150 7 208 5.02E-69 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 GBCGDNIH2_RS12580 b0200a773f9e16dcd874f9610acced7e 215 Gene3D G3DSA:1.10.1670.10 118 213 1.0E-30 T 29-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 GBCGDNIH2_RS12580 b0200a773f9e16dcd874f9610acced7e 215 PIRSF PIRSF001435 1 209 3.2E-47 T 29-03-2018 GBCGDNIH2_RS12580 b0200a773f9e16dcd874f9610acced7e 215 TIGRFAM TIGR01083 nth: endonuclease III 8 194 3.7E-76 T 29-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 GBCGDNIH2_RS12580 b0200a773f9e16dcd874f9610acced7e 215 Hamap MF_00942 Endonuclease III [nth]. 1 209 35.288 T 29-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 GBCGDNIH2_RS12580 b0200a773f9e16dcd874f9610acced7e 215 Pfam PF00633 Helix-hairpin-helix motif 99 127 4.0E-10 T 29-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 GBCGDNIH2_RS12580 b0200a773f9e16dcd874f9610acced7e 215 ProSitePatterns PS01155 Endonuclease III family signature. 102 131 - T 29-03-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 GBCGDNIH2_RS10440 cb8d0bf1f7f0dcf35ffd6bf237513028 230 Gene3D G3DSA:3.40.50.2300 2 122 3.8E-32 T 29-03-2018 GBCGDNIH2_RS10440 cb8d0bf1f7f0dcf35ffd6bf237513028 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 228 1.7E-21 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 GBCGDNIH2_RS10440 cb8d0bf1f7f0dcf35ffd6bf237513028 230 SMART SM00448 5 119 3.5E-35 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GBCGDNIH2_RS10440 cb8d0bf1f7f0dcf35ffd6bf237513028 230 SUPERFAMILY SSF46894 129 228 5.1E-20 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 GBCGDNIH2_RS10440 cb8d0bf1f7f0dcf35ffd6bf237513028 230 SUPERFAMILY SSF52172 3 131 2.13E-36 T 29-03-2018 IPR011006 CheY-like superfamily GBCGDNIH2_RS10440 cb8d0bf1f7f0dcf35ffd6bf237513028 230 Pfam PF00072 Response regulator receiver domain 7 120 2.0E-22 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GBCGDNIH2_RS10440 cb8d0bf1f7f0dcf35ffd6bf237513028 230 Gene3D G3DSA:1.10.10.10 123 230 4.8E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS10440 cb8d0bf1f7f0dcf35ffd6bf237513028 230 SMART SM00862 153 228 1.2E-18 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 GBCGDNIH2_RS03370 0924758818edc0afe054caa4eca8a445 252 Gene3D G3DSA:3.40.1010.10 2 125 3.7E-27 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GBCGDNIH2_RS03370 0924758818edc0afe054caa4eca8a445 252 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 6 213 8.7E-35 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GBCGDNIH2_RS03370 0924758818edc0afe054caa4eca8a445 252 Gene3D G3DSA:3.30.950.10 126 248 4.0E-44 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GBCGDNIH2_RS03370 0924758818edc0afe054caa4eca8a445 252 TIGRFAM TIGR01466 cobJ_cbiH: precorrin-3B C17-methyltransferase 5 249 5.2E-79 T 29-03-2018 IPR006363 Precorrin-3B C17-methyltransferase domain GO:0008168|GO:0009236 GBCGDNIH2_RS03370 0924758818edc0afe054caa4eca8a445 252 SUPERFAMILY SSF53790 1 234 2.62E-48 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GBCGDNIH2_RS02145 17880f5651e31fff505c90e009910d78 873 PIRSF PIRSF037677 214 813 4.6E-115 T 29-03-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 GBCGDNIH2_RS02145 17880f5651e31fff505c90e009910d78 873 PIRSF PIRSF037677 1 175 1.9E-31 T 29-03-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 GBCGDNIH2_RS02145 17880f5651e31fff505c90e009910d78 873 Gene3D G3DSA:1.10.1420.10 249 393 2.6E-28 T 29-03-2018 GBCGDNIH2_RS02145 17880f5651e31fff505c90e009910d78 873 SMART SM00533 269 579 3.0E-61 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 GBCGDNIH2_RS02145 17880f5651e31fff505c90e009910d78 873 SUPERFAMILY SSF53150 109 263 2.75E-28 T 29-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 GBCGDNIH2_RS02145 17880f5651e31fff505c90e009910d78 873 Pfam PF05192 MutS domain III 255 547 3.5E-33 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 GBCGDNIH2_RS02145 17880f5651e31fff505c90e009910d78 873 Pfam PF05190 MutS family domain IV 414 506 4.9E-17 T 29-03-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 GBCGDNIH2_RS02145 17880f5651e31fff505c90e009910d78 873 Pfam PF00488 MutS domain V 601 788 1.2E-76 T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 GBCGDNIH2_RS02145 17880f5651e31fff505c90e009910d78 873 SUPERFAMILY SSF48334 253 551 1.7E-67 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 GBCGDNIH2_RS02145 17880f5651e31fff505c90e009910d78 873 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 1 856 5.3E-239 T 29-03-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 GBCGDNIH2_RS02145 17880f5651e31fff505c90e009910d78 873 Gene3D G3DSA:3.40.50.300 555 823 1.2E-42 T 29-03-2018 GBCGDNIH2_RS02145 17880f5651e31fff505c90e009910d78 873 Pfam PF05188 MutS domain II 120 236 1.4E-11 T 29-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 GBCGDNIH2_RS02145 17880f5651e31fff505c90e009910d78 873 Pfam PF01624 MutS domain I 1 111 2.4E-38 T 29-03-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 GBCGDNIH2_RS02145 17880f5651e31fff505c90e009910d78 873 Gene3D G3DSA:3.30.420.110 124 247 4.0E-20 T 29-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 GBCGDNIH2_RS02145 17880f5651e31fff505c90e009910d78 873 SMART SM00534 598 785 2.3E-103 T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 GBCGDNIH2_RS02145 17880f5651e31fff505c90e009910d78 873 SUPERFAMILY SSF52540 555 788 4.71E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS02145 17880f5651e31fff505c90e009910d78 873 Gene3D G3DSA:3.40.1170.10 1 123 4.6E-43 T 29-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 GBCGDNIH2_RS02145 17880f5651e31fff505c90e009910d78 873 Gene3D G3DSA:1.10.1420.10 394 523 1.0E-24 T 29-03-2018 GBCGDNIH2_RS02145 17880f5651e31fff505c90e009910d78 873 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 679 695 - T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 GBCGDNIH2_RS02145 17880f5651e31fff505c90e009910d78 873 SUPERFAMILY SSF55271 1 107 8.37E-37 T 29-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 GBCGDNIH2_RS00535 27e1d0885727e50172bdc8edc9d9dfcb 314 Pfam PF00535 Glycosyl transferase family 2 10 122 1.4E-14 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 GBCGDNIH2_RS00535 27e1d0885727e50172bdc8edc9d9dfcb 314 SUPERFAMILY SSF53448 6 231 3.56E-31 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS00535 27e1d0885727e50172bdc8edc9d9dfcb 314 Gene3D G3DSA:3.90.550.10 2 281 2.6E-22 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS05610 ddee74bf82bfaf51999844a6475806a3 420 Gene3D G3DSA:3.65.10.10 223 420 2.2E-47 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 GBCGDNIH2_RS05610 ddee74bf82bfaf51999844a6475806a3 420 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 417 1.1E-175 T 29-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GBCGDNIH2_RS05610 ddee74bf82bfaf51999844a6475806a3 420 Gene3D G3DSA:3.65.10.10 21 222 1.7E-51 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 GBCGDNIH2_RS05610 ddee74bf82bfaf51999844a6475806a3 420 SUPERFAMILY SSF55205 1 419 1.06E-139 T 29-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 GBCGDNIH2_RS05610 ddee74bf82bfaf51999844a6475806a3 420 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 418 45.177 T 29-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GBCGDNIH2_RS05610 ddee74bf82bfaf51999844a6475806a3 420 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 408 1.1E-101 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 GBCGDNIH2_RS07985 620161921f81d6b47eaa50dcb220701f 356 SUPERFAMILY SSF55681 93 343 5.27E-73 T 29-03-2018 GBCGDNIH2_RS07985 620161921f81d6b47eaa50dcb220701f 356 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 21 88 1.3E-20 T 29-03-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 GBCGDNIH2_RS07985 620161921f81d6b47eaa50dcb220701f 356 Gene3D G3DSA:3.30.930.10 8 344 8.9E-81 T 29-03-2018 GBCGDNIH2_RS07985 620161921f81d6b47eaa50dcb220701f 356 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 39 341 3.4E-99 T 29-03-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 GBCGDNIH2_RS07985 620161921f81d6b47eaa50dcb220701f 356 Pfam PF01409 tRNA synthetases class II core domain (F) 93 341 5.9E-96 T 29-03-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 GBCGDNIH2_RS07985 620161921f81d6b47eaa50dcb220701f 356 SUPERFAMILY SSF46589 15 99 1.57E-16 T 29-03-2018 IPR010978 tRNA-binding arm GO:0000166 GBCGDNIH2_RS07985 620161921f81d6b47eaa50dcb220701f 356 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 9 342 44.74 T 29-03-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 GBCGDNIH2_RS01520 9f73b91801d0b27831f0a7d8b67bc8d6 349 Hamap MF_00916 Epoxyqueuosine reductase [queG]. 2 309 44.162 T 29-03-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 GBCGDNIH2_RS01520 9f73b91801d0b27831f0a7d8b67bc8d6 349 Gene3D G3DSA:3.30.70.20 193 260 1.7E-10 T 29-03-2018 GBCGDNIH2_RS01520 9f73b91801d0b27831f0a7d8b67bc8d6 349 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 9 341 5.7E-132 T 29-03-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 GBCGDNIH2_RS01520 9f73b91801d0b27831f0a7d8b67bc8d6 349 Pfam PF13484 4Fe-4S double cluster binding domain 186 250 5.8E-18 T 29-03-2018 GBCGDNIH2_RS01520 9f73b91801d0b27831f0a7d8b67bc8d6 349 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 187 198 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site GBCGDNIH2_RS01520 9f73b91801d0b27831f0a7d8b67bc8d6 349 Gene3D G3DSA:3.30.70.20 109 192 3.2E-4 T 29-03-2018 GBCGDNIH2_RS01520 9f73b91801d0b27831f0a7d8b67bc8d6 349 Gene3D G3DSA:1.25.40.70 261 344 8.6E-4 T 29-03-2018 GBCGDNIH2_RS01520 9f73b91801d0b27831f0a7d8b67bc8d6 349 SUPERFAMILY SSF46548 133 251 1.67E-18 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 GBCGDNIH2_RS01520 9f73b91801d0b27831f0a7d8b67bc8d6 349 Pfam PF08331 Domain of unknown function (DUF1730) 58 134 5.2E-22 T 29-03-2018 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700 GBCGDNIH2_RS02045 db5553c616f5cbd1eb7b0c8d03310c82 324 Pfam PF03668 P-loop ATPase protein family 9 285 3.2E-72 T 29-03-2018 IPR005337 RapZ-like family GO:0005524 GBCGDNIH2_RS02045 db5553c616f5cbd1eb7b0c8d03310c82 324 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 7 286 37.068 T 29-03-2018 IPR005337 RapZ-like family GO:0005524 GBCGDNIH2_RS02045 db5553c616f5cbd1eb7b0c8d03310c82 324 Gene3D G3DSA:3.40.50.300 23 156 5.0E-8 T 29-03-2018 GBCGDNIH2_RS02045 db5553c616f5cbd1eb7b0c8d03310c82 324 PIRSF PIRSF005052 7 289 1.1E-83 T 29-03-2018 IPR005337 RapZ-like family GO:0005524 GBCGDNIH2_RS02045 db5553c616f5cbd1eb7b0c8d03310c82 324 Gene3D G3DSA:3.40.50.300 2 22 0.0028 T 29-03-2018 GBCGDNIH2_RS02045 db5553c616f5cbd1eb7b0c8d03310c82 324 SUPERFAMILY SSF52540 8 155 7.31E-11 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS02045 db5553c616f5cbd1eb7b0c8d03310c82 324 SUPERFAMILY SSF52540 8 41 3.88E-5 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS02045 db5553c616f5cbd1eb7b0c8d03310c82 324 SUPERFAMILY SSF52540 162 233 3.88E-5 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS08825 706985e507b833badd600593b2bf0adf 742 Gene3D G3DSA:1.10.520.10 445 606 7.6E-42 T 29-03-2018 GBCGDNIH2_RS08825 706985e507b833badd600593b2bf0adf 742 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 60 73 6.6E-41 T 29-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 GBCGDNIH2_RS08825 706985e507b833badd600593b2bf0adf 742 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 75 100 6.6E-41 T 29-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 GBCGDNIH2_RS08825 706985e507b833badd600593b2bf0adf 742 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 484 510 6.6E-41 T 29-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 GBCGDNIH2_RS08825 706985e507b833badd600593b2bf0adf 742 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 268 291 6.6E-41 T 29-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 GBCGDNIH2_RS08825 706985e507b833badd600593b2bf0adf 742 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 34 56 6.6E-41 T 29-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 GBCGDNIH2_RS08825 706985e507b833badd600593b2bf0adf 742 Gene3D G3DSA:1.10.520.10 64 213 6.6E-35 T 29-03-2018 GBCGDNIH2_RS08825 706985e507b833badd600593b2bf0adf 742 Gene3D G3DSA:1.10.420.10 607 715 2.4E-36 T 29-03-2018 GBCGDNIH2_RS08825 706985e507b833badd600593b2bf0adf 742 TIGRFAM TIGR00198 cat_per_HPI: catalase/peroxidase HPI 36 741 0.0 T 29-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 GBCGDNIH2_RS08825 706985e507b833badd600593b2bf0adf 742 Pfam PF00141 Peroxidase 407 714 4.0E-38 T 29-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 GBCGDNIH2_RS08825 706985e507b833badd600593b2bf0adf 742 Pfam PF00141 Peroxidase 90 399 7.4E-47 T 29-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 GBCGDNIH2_RS08825 706985e507b833badd600593b2bf0adf 742 Gene3D G3DSA:1.10.420.10 237 426 3.2E-36 T 29-03-2018 GBCGDNIH2_RS08825 706985e507b833badd600593b2bf0adf 742 SUPERFAMILY SSF48113 434 739 5.16E-113 T 29-03-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 GBCGDNIH2_RS08825 706985e507b833badd600593b2bf0adf 742 Hamap MF_01961 Catalase-peroxidase [katG]. 18 740 40.683 T 29-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 GBCGDNIH2_RS08825 706985e507b833badd600593b2bf0adf 742 ProSitePatterns PS00435 Peroxidases proximal heme-ligand signature. 260 270 - T 29-03-2018 IPR019793 Peroxidases heam-ligand binding site Reactome: R-HSA-2408557 GBCGDNIH2_RS08825 706985e507b833badd600593b2bf0adf 742 PRINTS PR00458 Haem peroxidase superfamily signature 176 188 1.8E-15 T 29-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 GBCGDNIH2_RS08825 706985e507b833badd600593b2bf0adf 742 PRINTS PR00458 Haem peroxidase superfamily signature 260 275 1.8E-15 T 29-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 GBCGDNIH2_RS08825 706985e507b833badd600593b2bf0adf 742 PRINTS PR00458 Haem peroxidase superfamily signature 98 112 1.8E-15 T 29-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 GBCGDNIH2_RS08825 706985e507b833badd600593b2bf0adf 742 PRINTS PR00458 Haem peroxidase superfamily signature 320 335 1.8E-15 T 29-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 GBCGDNIH2_RS08825 706985e507b833badd600593b2bf0adf 742 PRINTS PR00458 Haem peroxidase superfamily signature 158 175 1.8E-15 T 29-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 GBCGDNIH2_RS08825 706985e507b833badd600593b2bf0adf 742 SUPERFAMILY SSF48113 32 433 8.4E-141 T 29-03-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 GBCGDNIH2_RS08825 706985e507b833badd600593b2bf0adf 742 ProSitePatterns PS00436 Peroxidases active site signature. 98 109 - T 29-03-2018 IPR019794 Peroxidase, active site GO:0004601|GO:0055114 GBCGDNIH2_RS06825 69534b4bf49b783f8ca848f132949bfc 1055 SUPERFAMILY SSF82866 291 497 2.22E-38 T 29-03-2018 GBCGDNIH2_RS06825 69534b4bf49b783f8ca848f132949bfc 1055 Gene3D G3DSA:1.20.1640.10 284 507 2.9E-39 T 29-03-2018 GBCGDNIH2_RS06825 69534b4bf49b783f8ca848f132949bfc 1055 Gene3D G3DSA:3.30.2090.10 181 267 2.9E-15 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains GBCGDNIH2_RS06825 69534b4bf49b783f8ca848f132949bfc 1055 SUPERFAMILY SSF82714 721 808 1.7E-11 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains GBCGDNIH2_RS06825 69534b4bf49b783f8ca848f132949bfc 1055 SUPERFAMILY SSF82693 42 127 1.75E-19 T 29-03-2018 GBCGDNIH2_RS06825 69534b4bf49b783f8ca848f132949bfc 1055 Gene3D G3DSA:3.30.2090.10 721 810 5.3E-15 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains GBCGDNIH2_RS06825 69534b4bf49b783f8ca848f132949bfc 1055 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 1 1029 3.9E-294 T 29-03-2018 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 GBCGDNIH2_RS06825 69534b4bf49b783f8ca848f132949bfc 1055 Gene3D G3DSA:3.30.70.1430 564 664 1.5E-8 T 29-03-2018 GBCGDNIH2_RS06825 69534b4bf49b783f8ca848f132949bfc 1055 Gene3D G3DSA:1.20.1640.10 811 1030 4.5E-35 T 29-03-2018 GBCGDNIH2_RS06825 69534b4bf49b783f8ca848f132949bfc 1055 PRINTS PR00702 Acriflavin resistance protein family signature 12 36 8.7E-36 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS06825 69534b4bf49b783f8ca848f132949bfc 1055 PRINTS PR00702 Acriflavin resistance protein family signature 386 410 8.7E-36 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS06825 69534b4bf49b783f8ca848f132949bfc 1055 PRINTS PR00702 Acriflavin resistance protein family signature 549 566 8.7E-36 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS06825 69534b4bf49b783f8ca848f132949bfc 1055 PRINTS PR00702 Acriflavin resistance protein family signature 331 354 8.7E-36 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS06825 69534b4bf49b783f8ca848f132949bfc 1055 PRINTS PR00702 Acriflavin resistance protein family signature 358 379 8.7E-36 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS06825 69534b4bf49b783f8ca848f132949bfc 1055 PRINTS PR00702 Acriflavin resistance protein family signature 470 493 8.7E-36 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS06825 69534b4bf49b783f8ca848f132949bfc 1055 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 8.7E-36 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS06825 69534b4bf49b783f8ca848f132949bfc 1055 SUPERFAMILY SSF82866 806 1029 4.32E-50 T 29-03-2018 GBCGDNIH2_RS06825 69534b4bf49b783f8ca848f132949bfc 1055 SUPERFAMILY SSF82693 139 182 1.5E-19 T 29-03-2018 GBCGDNIH2_RS06825 69534b4bf49b783f8ca848f132949bfc 1055 SUPERFAMILY SSF82693 268 325 1.5E-19 T 29-03-2018 GBCGDNIH2_RS06825 69534b4bf49b783f8ca848f132949bfc 1055 Pfam PF00873 AcrB/AcrD/AcrF family 6 1027 4.8E-273 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS06825 69534b4bf49b783f8ca848f132949bfc 1055 SUPERFAMILY SSF82714 184 265 4.97E-13 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains GBCGDNIH2_RS06825 69534b4bf49b783f8ca848f132949bfc 1055 Gene3D G3DSA:3.30.70.1430 42 141 1.9E-20 T 29-03-2018 GBCGDNIH2_RS01315 730fedd6e63404a626a271ce16a4a13f 202 Gene3D G3DSA:3.40.1360.10 76 174 6.7E-29 T 29-03-2018 GBCGDNIH2_RS01315 730fedd6e63404a626a271ce16a4a13f 202 SUPERFAMILY SSF111304 4 201 1.44E-65 T 29-03-2018 IPR023627 Recombination protein RecR GBCGDNIH2_RS01315 730fedd6e63404a626a271ce16a4a13f 202 TIGRFAM TIGR00615 recR: recombination protein RecR 5 200 9.0E-58 T 29-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 GBCGDNIH2_RS01315 730fedd6e63404a626a271ce16a4a13f 202 Pfam PF02132 RecR protein 40 76 4.6E-13 T 29-03-2018 IPR023628 Recombination protein RecR, C4-type zinc finger GBCGDNIH2_RS01315 730fedd6e63404a626a271ce16a4a13f 202 Pfam PF13662 Toprim domain 80 175 2.3E-19 T 29-03-2018 IPR006171 TOPRIM domain GBCGDNIH2_RS01315 730fedd6e63404a626a271ce16a4a13f 202 Hamap MF_00017 Recombination protein RecR [recR]. 1 202 88.889 T 29-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 GBCGDNIH2_RS01315 730fedd6e63404a626a271ce16a4a13f 202 SMART SM00493 79 169 0.0054 T 29-03-2018 IPR006171 TOPRIM domain GBCGDNIH2_RS00770 8f703f3e9d2feb3ea46096c00b6b9678 320 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 1.2E-12 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 GBCGDNIH2_RS00770 8f703f3e9d2feb3ea46096c00b6b9678 320 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 5 20 1.2E-12 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 GBCGDNIH2_RS00770 8f703f3e9d2feb3ea46096c00b6b9678 320 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 24 35 1.2E-12 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 GBCGDNIH2_RS00770 8f703f3e9d2feb3ea46096c00b6b9678 320 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 37 52 1.2E-12 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 GBCGDNIH2_RS00770 8f703f3e9d2feb3ea46096c00b6b9678 320 Pfam PF08241 Methyltransferase domain 149 245 2.4E-23 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 GBCGDNIH2_RS00770 8f703f3e9d2feb3ea46096c00b6b9678 320 Pfam PF01022 Bacterial regulatory protein, arsR family 11 55 4.1E-12 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 GBCGDNIH2_RS00770 8f703f3e9d2feb3ea46096c00b6b9678 320 SUPERFAMILY SSF46785 2 185 2.3E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS00770 8f703f3e9d2feb3ea46096c00b6b9678 320 Gene3D G3DSA:3.40.50.150 140 305 2.8E-33 T 29-03-2018 GBCGDNIH2_RS00770 8f703f3e9d2feb3ea46096c00b6b9678 320 Gene3D G3DSA:1.10.10.10 2 139 1.9E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS00770 8f703f3e9d2feb3ea46096c00b6b9678 320 SUPERFAMILY SSF53335 134 303 3.16E-38 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GBCGDNIH2_RS00770 8f703f3e9d2feb3ea46096c00b6b9678 320 SMART SM00418 3 81 1.1E-14 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 GBCGDNIH2_RS11240 2a6283e054c4faf3f4ec5e0dc9696088 570 SUPERFAMILY SSF51338 426 479 6.99E-6 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 GBCGDNIH2_RS11240 2a6283e054c4faf3f4ec5e0dc9696088 570 TIGRFAM TIGR01792 urease_alph: urease, alpha subunit 5 570 6.8E-290 T 29-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 GBCGDNIH2_RS11240 2a6283e054c4faf3f4ec5e0dc9696088 570 ProSitePatterns PS00145 Urease active site. 319 335 - T 29-03-2018 IPR017950 Urease active site GO:0009039 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 GBCGDNIH2_RS11240 2a6283e054c4faf3f4ec5e0dc9696088 570 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 336 352 3.9E-32 T 29-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 GBCGDNIH2_RS11240 2a6283e054c4faf3f4ec5e0dc9696088 570 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 429 442 3.9E-32 T 29-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 GBCGDNIH2_RS11240 2a6283e054c4faf3f4ec5e0dc9696088 570 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 297 314 3.9E-32 T 29-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 GBCGDNIH2_RS11240 2a6283e054c4faf3f4ec5e0dc9696088 570 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 403 418 3.9E-32 T 29-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 GBCGDNIH2_RS11240 2a6283e054c4faf3f4ec5e0dc9696088 570 SUPERFAMILY SSF51556 132 433 1.0E-191 T 29-03-2018 IPR032466 Metal-dependent hydrolase GBCGDNIH2_RS11240 2a6283e054c4faf3f4ec5e0dc9696088 570 SUPERFAMILY SSF51556 482 570 1.0E-191 T 29-03-2018 IPR032466 Metal-dependent hydrolase GBCGDNIH2_RS11240 2a6283e054c4faf3f4ec5e0dc9696088 570 Gene3D G3DSA:2.30.40.10 66 144 4.8E-18 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 GBCGDNIH2_RS11240 2a6283e054c4faf3f4ec5e0dc9696088 570 SUPERFAMILY SSF51338 3 179 9.1E-62 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 GBCGDNIH2_RS11240 2a6283e054c4faf3f4ec5e0dc9696088 570 Pfam PF00449 Urease alpha-subunit, N-terminal domain 4 121 1.2E-56 T 29-03-2018 IPR011612 Urease alpha-subunit, N-terminal domain KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 GBCGDNIH2_RS11240 2a6283e054c4faf3f4ec5e0dc9696088 570 Gene3D G3DSA:3.20.20.140 424 556 7.5E-43 T 29-03-2018 GBCGDNIH2_RS11240 2a6283e054c4faf3f4ec5e0dc9696088 570 Gene3D G3DSA:3.20.20.140 145 423 2.3E-159 T 29-03-2018 GBCGDNIH2_RS11240 2a6283e054c4faf3f4ec5e0dc9696088 570 ProSitePatterns PS01120 Urease nickel ligands signature. 129 142 - T 29-03-2018 IPR029754 Urease nickel binding site GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 GBCGDNIH2_RS11240 2a6283e054c4faf3f4ec5e0dc9696088 570 Hamap MF_01953 Urease subunit alpha [ureC]. 3 570 56.177 T 29-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 GBCGDNIH2_RS11240 2a6283e054c4faf3f4ec5e0dc9696088 570 Pfam PF01979 Amidohydrolase family 127 453 2.4E-71 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 GBCGDNIH2_RS04435 7c7c62118e322040445b1c34839b93e4 222 SUPERFAMILY SSF52833 21 212 4.0E-58 T 29-03-2018 IPR012336 Thioredoxin-like fold GBCGDNIH2_RS04435 7c7c62118e322040445b1c34839b93e4 222 Gene3D G3DSA:3.40.30.10 9 170 9.8E-36 T 29-03-2018 GBCGDNIH2_RS04435 7c7c62118e322040445b1c34839b93e4 222 Pfam PF00578 AhpC/TSA family 25 153 1.7E-31 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 GBCGDNIH2_RS04435 7c7c62118e322040445b1c34839b93e4 222 Gene3D G3DSA:3.30.1020.10 171 217 5.3E-11 T 29-03-2018 GBCGDNIH2_RS04435 7c7c62118e322040445b1c34839b93e4 222 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 174 203 7.0E-8 T 29-03-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 GBCGDNIH2_RS04435 7c7c62118e322040445b1c34839b93e4 222 PIRSF PIRSF000239 18 220 3.4E-69 T 29-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 GBCGDNIH2_RS06570 e1f359709164b363d089b69e63259503 173 Gene3D G3DSA:2.40.50.140 1 119 1.9E-43 T 29-03-2018 GBCGDNIH2_RS06570 e1f359709164b363d089b69e63259503 173 Hamap MF_00984 Single-stranded DNA-binding protein. 5 118 35.448 T 29-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 GBCGDNIH2_RS06570 e1f359709164b363d089b69e63259503 173 SUPERFAMILY SSF50249 4 173 5.14E-53 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold GBCGDNIH2_RS06570 e1f359709164b363d089b69e63259503 173 Pfam PF00436 Single-strand binding protein family 5 107 5.6E-40 T 29-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 GBCGDNIH2_RS06570 e1f359709164b363d089b69e63259503 173 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 3 173 3.4E-48 T 29-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 GBCGDNIH2_RS11290 eee8baa0149f4e9b8d1c3d7d31c52234 520 Gene3D G3DSA:3.40.50.620 5 273 6.6E-47 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GBCGDNIH2_RS11290 eee8baa0149f4e9b8d1c3d7d31c52234 520 Hamap MF_00177 Lysine--tRNA ligase [lysS]. 6 512 28.636 T 29-03-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 GBCGDNIH2_RS11290 eee8baa0149f4e9b8d1c3d7d31c52234 520 Pfam PF01921 tRNA synthetases class I (K) 6 355 8.9E-123 T 29-03-2018 GBCGDNIH2_RS11290 eee8baa0149f4e9b8d1c3d7d31c52234 520 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 36 45 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 GBCGDNIH2_RS11290 eee8baa0149f4e9b8d1c3d7d31c52234 520 Gene3D G3DSA:1.10.10.350 419 512 4.2E-18 T 29-03-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 GBCGDNIH2_RS11290 eee8baa0149f4e9b8d1c3d7d31c52234 520 SUPERFAMILY SSF48163 321 512 1.44E-35 T 29-03-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 GBCGDNIH2_RS11290 eee8baa0149f4e9b8d1c3d7d31c52234 520 SUPERFAMILY SSF52374 8 322 2.82E-54 T 29-03-2018 GBCGDNIH2_RS03755 985a165af61448ec6c5eb23bce2e81d9 437 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 276 309 - T 29-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 GBCGDNIH2_RS03755 985a165af61448ec6c5eb23bce2e81d9 437 Pfam PF13241 Putative NAD(P)-binding 7 94 3.6E-10 T 29-03-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 GBCGDNIH2_RS03755 985a165af61448ec6c5eb23bce2e81d9 437 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 201 215 - T 29-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 GBCGDNIH2_RS03755 985a165af61448ec6c5eb23bce2e81d9 437 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 196 428 8.7E-84 T 29-03-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 GBCGDNIH2_RS03755 985a165af61448ec6c5eb23bce2e81d9 437 Gene3D G3DSA:3.30.950.10 321 434 8.0E-27 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GBCGDNIH2_RS03755 985a165af61448ec6c5eb23bce2e81d9 437 SUPERFAMILY SSF75615 93 187 5.23E-24 T 29-03-2018 GBCGDNIH2_RS03755 985a165af61448ec6c5eb23bce2e81d9 437 Gene3D G3DSA:3.30.160.110 86 125 3.0E-19 T 29-03-2018 GBCGDNIH2_RS03755 985a165af61448ec6c5eb23bce2e81d9 437 Pfam PF14824 Sirohaem biosynthesis protein central 98 124 6.2E-10 T 29-03-2018 IPR028281 Siroheme synthase, central domain KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 GBCGDNIH2_RS03755 985a165af61448ec6c5eb23bce2e81d9 437 Pfam PF10414 Sirohaem synthase dimerisation region 129 185 9.2E-16 T 29-03-2018 IPR019478 Sirohaem synthase, dimerisation domain GO:0006779|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 GBCGDNIH2_RS03755 985a165af61448ec6c5eb23bce2e81d9 437 SUPERFAMILY SSF53790 195 431 1.7E-72 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GBCGDNIH2_RS03755 985a165af61448ec6c5eb23bce2e81d9 437 Gene3D G3DSA:3.40.50.720 49 85 0.011 T 29-03-2018 GBCGDNIH2_RS03755 985a165af61448ec6c5eb23bce2e81d9 437 Gene3D G3DSA:3.40.1010.10 196 320 4.8E-35 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GBCGDNIH2_RS03755 985a165af61448ec6c5eb23bce2e81d9 437 Gene3D G3DSA:3.40.50.720 1 42 0.003 T 29-03-2018 GBCGDNIH2_RS03755 985a165af61448ec6c5eb23bce2e81d9 437 SUPERFAMILY SSF51735 1 91 2.17E-9 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS03755 985a165af61448ec6c5eb23bce2e81d9 437 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 43 185 1.3E-42 T 29-03-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 GBCGDNIH2_RS03755 985a165af61448ec6c5eb23bce2e81d9 437 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 198 407 8.4E-46 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GBCGDNIH2_RS03755 985a165af61448ec6c5eb23bce2e81d9 437 Gene3D G3DSA:1.10.8.210 130 187 1.9E-13 T 29-03-2018 IPR019478 Sirohaem synthase, dimerisation domain GO:0006779|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 GBCGDNIH2_RS03755 985a165af61448ec6c5eb23bce2e81d9 437 PIRSF PIRSF036426 39 436 1.6E-146 T 29-03-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 GBCGDNIH2_RS03755 985a165af61448ec6c5eb23bce2e81d9 437 PIRSF PIRSF036426 1 43 2.7E-6 T 29-03-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 GBCGDNIH2_RS00055 1ba09f02b871ec1f9c9ac3c9fd3564de 629 SMART SM01228 549 620 1.5E-26 T 29-03-2018 GBCGDNIH2_RS00055 1ba09f02b871ec1f9c9ac3c9fd3564de 629 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 10 627 39.949 T 29-03-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 GBCGDNIH2_RS00055 1ba09f02b871ec1f9c9ac3c9fd3564de 629 Gene3D G3DSA:3.50.50.60 10 272 3.7E-66 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS00055 1ba09f02b871ec1f9c9ac3c9fd3564de 629 SUPERFAMILY SSF51905 102 268 3.4E-41 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS00055 1ba09f02b871ec1f9c9ac3c9fd3564de 629 SUPERFAMILY SSF51905 12 71 3.4E-41 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS00055 1ba09f02b871ec1f9c9ac3c9fd3564de 629 Pfam PF13932 GidA associated domain 409 618 2.6E-64 T 29-03-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 GBCGDNIH2_RS00055 1ba09f02b871ec1f9c9ac3c9fd3564de 629 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 12 625 2.3E-238 T 29-03-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 GBCGDNIH2_RS00055 1ba09f02b871ec1f9c9ac3c9fd3564de 629 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 280 294 - T 29-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 GBCGDNIH2_RS00055 1ba09f02b871ec1f9c9ac3c9fd3564de 629 Pfam PF01134 Glucose inhibited division protein A 13 405 8.8E-162 T 29-03-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 GBCGDNIH2_RS00055 1ba09f02b871ec1f9c9ac3c9fd3564de 629 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 375 398 - T 29-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 GBCGDNIH2_RS05955 49ec4659de8ce6873dd9e3c1098ae99c 359 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 260 333 3.2E-29 T 29-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 GBCGDNIH2_RS05955 49ec4659de8ce6873dd9e3c1098ae99c 359 Gene3D G3DSA:1.10.8.60 191 261 4.3E-30 T 29-03-2018 GBCGDNIH2_RS05955 49ec4659de8ce6873dd9e3c1098ae99c 359 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 258 335 3.0E-32 T 29-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 GBCGDNIH2_RS05955 49ec4659de8ce6873dd9e3c1098ae99c 359 SMART SM00382 58 185 1.7E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS05955 49ec4659de8ce6873dd9e3c1098ae99c 359 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 17 242 4.0E-111 T 29-03-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 GBCGDNIH2_RS05955 49ec4659de8ce6873dd9e3c1098ae99c 359 Gene3D G3DSA:3.40.50.300 25 188 1.1E-26 T 29-03-2018 GBCGDNIH2_RS05955 49ec4659de8ce6873dd9e3c1098ae99c 359 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 359 164.129 T 29-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 GBCGDNIH2_RS05955 49ec4659de8ce6873dd9e3c1098ae99c 359 SUPERFAMILY SSF52540 27 258 6.0E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS05955 49ec4659de8ce6873dd9e3c1098ae99c 359 SUPERFAMILY SSF46785 263 337 5.99E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS05955 49ec4659de8ce6873dd9e3c1098ae99c 359 Gene3D G3DSA:1.10.10.10 264 334 3.2E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS05955 49ec4659de8ce6873dd9e3c1098ae99c 359 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 31 333 3.6E-131 T 29-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 GBCGDNIH2_RS00635 08df28e34833103e58925d2fe8f4f928 545 Gene3D G3DSA:3.90.76.10 52 172 4.8E-33 T 29-03-2018 GBCGDNIH2_RS00635 08df28e34833103e58925d2fe8f4f928 545 Gene3D G3DSA:3.10.105.10 308 509 2.3E-50 T 29-03-2018 GBCGDNIH2_RS00635 08df28e34833103e58925d2fe8f4f928 545 PIRSF PIRSF002741 2 530 8.1E-108 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 GBCGDNIH2_RS00635 08df28e34833103e58925d2fe8f4f928 545 Gene3D G3DSA:3.40.190.10 173 307 2.2E-41 T 29-03-2018 GBCGDNIH2_RS00635 08df28e34833103e58925d2fe8f4f928 545 SUPERFAMILY SSF53850 32 528 1.03E-122 T 29-03-2018 GBCGDNIH2_RS00635 08df28e34833103e58925d2fe8f4f928 545 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 80 450 1.3E-86 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain GBCGDNIH2_RS10455 1e06ce185d4b5e5f92511512f7d190d5 266 Gene3D G3DSA:3.40.50.880 20 260 6.8E-39 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like GBCGDNIH2_RS10455 1e06ce185d4b5e5f92511512f7d190d5 266 SUPERFAMILY SSF52317 37 242 9.62E-36 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like GBCGDNIH2_RS10455 1e06ce185d4b5e5f92511512f7d190d5 266 Pfam PF07722 Peptidase C26 3 223 3.9E-63 T 29-03-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 GBCGDNIH2_RS07050 069e34b167188f6895bda6204c60c730 486 SUPERFAMILY SSF56954 4 478 1.83E-106 T 29-03-2018 GBCGDNIH2_RS07050 069e34b167188f6895bda6204c60c730 486 Gene3D G3DSA:1.20.1600.10 19 479 3.1E-106 T 29-03-2018 GBCGDNIH2_RS07050 069e34b167188f6895bda6204c60c730 486 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 11 475 1.7E-109 T 29-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 GBCGDNIH2_RS07050 069e34b167188f6895bda6204c60c730 486 Pfam PF02321 Outer membrane efflux protein 61 265 5.0E-26 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 GBCGDNIH2_RS07050 069e34b167188f6895bda6204c60c730 486 Pfam PF02321 Outer membrane efflux protein 295 473 6.3E-27 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 GBCGDNIH2_RS11555 4bef6c283c0bf5f1e08cfbcb6096c031 258 SUPERFAMILY SSF51366 2 250 6.28E-83 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 GBCGDNIH2_RS11555 4bef6c283c0bf5f1e08cfbcb6096c031 258 Pfam PF00977 Histidine biosynthesis protein 5 233 6.3E-86 T 29-03-2018 IPR006062 Histidine biosynthesis GO:0000105 GBCGDNIH2_RS11555 4bef6c283c0bf5f1e08cfbcb6096c031 258 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 249 46.082 T 29-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 GBCGDNIH2_RS11555 4bef6c283c0bf5f1e08cfbcb6096c031 258 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 2 249 6.2E-101 T 29-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 GBCGDNIH2_RS11555 4bef6c283c0bf5f1e08cfbcb6096c031 258 Gene3D G3DSA:3.20.20.70 4 245 3.1E-66 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS02120 b3441e95a86deeb653c4f51528941332 339 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 4 315 5.5E-87 T 29-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 GBCGDNIH2_RS02120 b3441e95a86deeb653c4f51528941332 339 Pfam PF00294 pfkB family carbohydrate kinase 9 303 1.4E-45 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB GBCGDNIH2_RS02120 b3441e95a86deeb653c4f51528941332 339 Gene3D G3DSA:2.20.150.10 11 42 9.9E-11 T 29-03-2018 IPR023314 Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain GBCGDNIH2_RS02120 b3441e95a86deeb653c4f51528941332 339 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 258 271 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 GBCGDNIH2_RS02120 b3441e95a86deeb653c4f51528941332 339 Gene3D G3DSA:3.40.1190.20 43 321 1.5E-42 T 29-03-2018 IPR029056 Ribokinase-like GBCGDNIH2_RS02120 b3441e95a86deeb653c4f51528941332 339 PIRSF PIRSF000535 1 319 2.4E-82 T 29-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 GBCGDNIH2_RS02120 b3441e95a86deeb653c4f51528941332 339 SUPERFAMILY SSF53613 4 307 2.81E-61 T 29-03-2018 IPR029056 Ribokinase-like GBCGDNIH2_RS10360 f14428faecd9f5b1bf71eb5478c442ca 585 Pfam PF13537 Glutamine amidotransferase domain 48 162 4.9E-31 T 29-03-2018 IPR017932 Glutamine amidotransferase type 2 domain GBCGDNIH2_RS10360 f14428faecd9f5b1bf71eb5478c442ca 585 SUPERFAMILY SSF56235 1 212 5.83E-47 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal GBCGDNIH2_RS10360 f14428faecd9f5b1bf71eb5478c442ca 585 Gene3D G3DSA:3.40.50.620 219 574 2.1E-69 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GBCGDNIH2_RS10360 f14428faecd9f5b1bf71eb5478c442ca 585 PIRSF PIRSF001589 1 581 4.6E-159 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 GBCGDNIH2_RS10360 f14428faecd9f5b1bf71eb5478c442ca 585 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 506 4.7E-112 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 GBCGDNIH2_RS10360 f14428faecd9f5b1bf71eb5478c442ca 585 Pfam PF00733 Asparagine synthase 237 517 3.7E-75 T 29-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 GBCGDNIH2_RS10360 f14428faecd9f5b1bf71eb5478c442ca 585 Gene3D G3DSA:3.60.20.10 1 217 8.9E-41 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal GBCGDNIH2_RS10360 f14428faecd9f5b1bf71eb5478c442ca 585 SUPERFAMILY SSF52402 228 376 1.45E-65 T 29-03-2018 GBCGDNIH2_RS10360 f14428faecd9f5b1bf71eb5478c442ca 585 SUPERFAMILY SSF52402 423 565 1.45E-65 T 29-03-2018 GBCGDNIH2_RS04975 77ee3de8236d1817125beab547a3e747 249 Gene3D G3DSA:1.10.10.10 142 249 8.6E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS04975 77ee3de8236d1817125beab547a3e747 249 Pfam PF00072 Response regulator receiver domain 24 136 5.9E-33 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GBCGDNIH2_RS04975 77ee3de8236d1817125beab547a3e747 249 TIGRFAM TIGR02154 PhoB: phosphate regulon transcriptional regulatory protein PhoB 22 245 3.0E-101 T 29-03-2018 IPR011879 Signal transduction response regulator, phosphate regulon transcriptional regulatory protein PhoB GO:0000156|GO:0000160|GO:0003677|GO:0006817 GBCGDNIH2_RS04975 77ee3de8236d1817125beab547a3e747 249 SMART SM00448 22 135 7.5E-50 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GBCGDNIH2_RS04975 77ee3de8236d1817125beab547a3e747 249 SMART SM00862 169 244 9.0E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 GBCGDNIH2_RS04975 77ee3de8236d1817125beab547a3e747 249 Gene3D G3DSA:3.40.50.2300 4 141 1.1E-42 T 29-03-2018 GBCGDNIH2_RS04975 77ee3de8236d1817125beab547a3e747 249 Pfam PF00486 Transcriptional regulatory protein, C terminal 170 244 5.0E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 GBCGDNIH2_RS04975 77ee3de8236d1817125beab547a3e747 249 SUPERFAMILY SSF52172 22 207 1.57E-47 T 29-03-2018 IPR011006 CheY-like superfamily GBCGDNIH2_RS11535 8f698895b557921b8905cb85bc39ffc9 259 SUPERFAMILY SSF51735 13 250 8.72E-61 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS11535 8f698895b557921b8905cb85bc39ffc9 259 Gene3D G3DSA:3.40.50.720 11 252 4.0E-52 T 29-03-2018 GBCGDNIH2_RS11535 8f698895b557921b8905cb85bc39ffc9 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 1.3E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS11535 8f698895b557921b8905cb85bc39ffc9 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 1.3E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS11535 8f698895b557921b8905cb85bc39ffc9 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 1.3E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS11535 8f698895b557921b8905cb85bc39ffc9 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 1.3E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS11535 8f698895b557921b8905cb85bc39ffc9 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 1.3E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS11535 8f698895b557921b8905cb85bc39ffc9 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 1.4E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS11535 8f698895b557921b8905cb85bc39ffc9 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 150 1.4E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS11535 8f698895b557921b8905cb85bc39ffc9 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 89 100 1.4E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS11535 8f698895b557921b8905cb85bc39ffc9 259 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 149 177 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 GBCGDNIH2_RS11535 8f698895b557921b8905cb85bc39ffc9 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 248 3.3E-42 T 29-03-2018 GBCGDNIH2_RS00960 bc44f24b5bffa36b755e46933bafcfcd 572 Pfam PF02470 MlaD protein 308 399 4.1E-7 T 29-03-2018 IPR003399 Mce/MlaD GBCGDNIH2_RS00960 bc44f24b5bffa36b755e46933bafcfcd 572 Pfam PF02470 MlaD protein 54 145 1.4E-10 T 29-03-2018 IPR003399 Mce/MlaD GBCGDNIH2_RS11355 016443112b7b71b7a959c6863c4c0262 250 SUPERFAMILY SSF88697 15 82 1.09E-13 T 29-03-2018 IPR015947 PUA-like domain GBCGDNIH2_RS11355 016443112b7b71b7a959c6863c4c0262 250 PIRSF PIRSF015601 15 242 7.1E-53 T 29-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 GBCGDNIH2_RS11355 016443112b7b71b7a959c6863c4c0262 250 Gene3D G3DSA:2.40.240.20 15 83 3.2E-16 T 29-03-2018 GBCGDNIH2_RS11355 016443112b7b71b7a959c6863c4c0262 250 SUPERFAMILY SSF75217 91 240 1.52E-38 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases GBCGDNIH2_RS11355 016443112b7b71b7a959c6863c4c0262 250 Gene3D G3DSA:3.40.1280.10 89 242 4.6E-42 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal GBCGDNIH2_RS11355 016443112b7b71b7a959c6863c4c0262 250 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 27 240 6.7E-32 T 29-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 GBCGDNIH2_RS11355 016443112b7b71b7a959c6863c4c0262 250 Pfam PF04452 RNA methyltransferase 30 240 3.4E-51 T 29-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 GBCGDNIH2_RS03090 73655392ad3139a2280815362c781202 387 Gene3D G3DSA:3.20.20.120 20 227 1.3E-22 T 29-03-2018 IPR029065 Enolase C-terminal domain-like GBCGDNIH2_RS03090 73655392ad3139a2280815362c781202 387 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 9 360 33.569 T 29-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 GBCGDNIH2_RS03090 73655392ad3139a2280815362c781202 387 SUPERFAMILY SSF51412 26 133 6.68E-10 T 29-03-2018 GBCGDNIH2_RS03090 73655392ad3139a2280815362c781202 387 SUPERFAMILY SSF56014 269 355 3.74E-13 T 29-03-2018 GBCGDNIH2_RS03090 73655392ad3139a2280815362c781202 387 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 11 356 1.8E-136 T 29-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 GBCGDNIH2_RS03090 73655392ad3139a2280815362c781202 387 PIRSF PIRSF004640 4 366 7.4E-145 T 29-03-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 GBCGDNIH2_RS03090 73655392ad3139a2280815362c781202 387 Pfam PF04551 GcpE protein 15 356 3.7E-130 T 29-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 GBCGDNIH2_RS09165 9bdb61f9c7e64081d63b67add064c6ae 265 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GBCGDNIH2_RS09165 9bdb61f9c7e64081d63b67add064c6ae 265 Pfam PF00005 ABC transporter 19 168 3.6E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GBCGDNIH2_RS09165 9bdb61f9c7e64081d63b67add064c6ae 265 SUPERFAMILY SSF52540 4 219 1.45E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS09165 9bdb61f9c7e64081d63b67add064c6ae 265 Gene3D G3DSA:3.40.50.300 1 257 6.8E-58 T 29-03-2018 GBCGDNIH2_RS09165 9bdb61f9c7e64081d63b67add064c6ae 265 SMART SM00382 28 218 4.2E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS03830 56b44b8582b8845fb7e222e1c12831bf 1211 Gene3D G3DSA:3.40.50.2000 750 897 2.8E-22 T 29-03-2018 GBCGDNIH2_RS03830 56b44b8582b8845fb7e222e1c12831bf 1211 Gene3D G3DSA:1.20.5.110 267 749 0.0015 T 29-03-2018 GBCGDNIH2_RS03830 56b44b8582b8845fb7e222e1c12831bf 1211 Pfam PF08241 Methyltransferase domain 50 143 2.6E-21 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 GBCGDNIH2_RS03830 56b44b8582b8845fb7e222e1c12831bf 1211 Pfam PF00535 Glycosyl transferase family 2 963 1093 3.2E-24 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 GBCGDNIH2_RS03830 56b44b8582b8845fb7e222e1c12831bf 1211 SUPERFAMILY SSF53335 35 185 5.77E-31 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GBCGDNIH2_RS03830 56b44b8582b8845fb7e222e1c12831bf 1211 Gene3D G3DSA:3.90.550.10 919 1192 6.4E-40 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS03830 56b44b8582b8845fb7e222e1c12831bf 1211 Gene3D G3DSA:3.40.50.150 19 203 9.4E-28 T 29-03-2018 GBCGDNIH2_RS03830 56b44b8582b8845fb7e222e1c12831bf 1211 SUPERFAMILY SSF53448 963 1168 3.28E-42 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS03830 56b44b8582b8845fb7e222e1c12831bf 1211 SUPERFAMILY SSF53756 571 904 3.49E-24 T 29-03-2018 GBCGDNIH2_RS03830 56b44b8582b8845fb7e222e1c12831bf 1211 Pfam PF13524 Glycosyl transferases group 1 830 907 1.6E-12 T 29-03-2018 GBCGDNIH2_RS01685 0e2b185c5273dbc7521def570cc70f0f 460 Gene3D G3DSA:3.30.230.10 248 459 2.8E-35 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup GBCGDNIH2_RS01685 0e2b185c5273dbc7521def570cc70f0f 460 Pfam PF13541 Subunit ChlI of Mg-chelatase 343 423 6.2E-8 T 29-03-2018 GBCGDNIH2_RS01685 0e2b185c5273dbc7521def570cc70f0f 460 SUPERFAMILY SSF52540 66 286 4.13E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS01685 0e2b185c5273dbc7521def570cc70f0f 460 PRINTS PR01874 DNA repair protein radA signature 171 195 8.3E-89 T 29-03-2018 GBCGDNIH2_RS01685 0e2b185c5273dbc7521def570cc70f0f 460 PRINTS PR01874 DNA repair protein radA signature 210 238 8.3E-89 T 29-03-2018 GBCGDNIH2_RS01685 0e2b185c5273dbc7521def570cc70f0f 460 PRINTS PR01874 DNA repair protein radA signature 245 271 8.3E-89 T 29-03-2018 GBCGDNIH2_RS01685 0e2b185c5273dbc7521def570cc70f0f 460 PRINTS PR01874 DNA repair protein radA signature 10 34 8.3E-89 T 29-03-2018 GBCGDNIH2_RS01685 0e2b185c5273dbc7521def570cc70f0f 460 PRINTS PR01874 DNA repair protein radA signature 319 342 8.3E-89 T 29-03-2018 GBCGDNIH2_RS01685 0e2b185c5273dbc7521def570cc70f0f 460 PRINTS PR01874 DNA repair protein radA signature 78 106 8.3E-89 T 29-03-2018 GBCGDNIH2_RS01685 0e2b185c5273dbc7521def570cc70f0f 460 PRINTS PR01874 DNA repair protein radA signature 120 137 8.3E-89 T 29-03-2018 GBCGDNIH2_RS01685 0e2b185c5273dbc7521def570cc70f0f 460 SMART SM00382 86 241 3.5E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS01685 0e2b185c5273dbc7521def570cc70f0f 460 SUPERFAMILY SSF54211 252 266 4.17E-34 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold GBCGDNIH2_RS01685 0e2b185c5273dbc7521def570cc70f0f 460 SUPERFAMILY SSF54211 300 454 4.17E-34 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold GBCGDNIH2_RS01685 0e2b185c5273dbc7521def570cc70f0f 460 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 450 2.2E-164 T 29-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 GBCGDNIH2_RS01685 0e2b185c5273dbc7521def570cc70f0f 460 Gene3D G3DSA:3.40.50.300 58 247 1.2E-21 T 29-03-2018 GBCGDNIH2_RS01685 0e2b185c5273dbc7521def570cc70f0f 460 Hamap MF_01498 DNA repair protein RadA [radA]. 21 456 43.106 T 29-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 GBCGDNIH2_RS01685 0e2b185c5273dbc7521def570cc70f0f 460 Pfam PF13481 AAA domain 69 219 3.5E-17 T 29-03-2018 GBCGDNIH2_RS11860 2e07813cfd55be31fb7e807faf4ac11d 398 Gene3D G3DSA:3.40.50.1100 138 307 8.8E-38 T 29-03-2018 GBCGDNIH2_RS11860 2e07813cfd55be31fb7e807faf4ac11d 398 Pfam PF01842 ACT domain 326 391 7.9E-8 T 29-03-2018 IPR002912 ACT domain GBCGDNIH2_RS11860 2e07813cfd55be31fb7e807faf4ac11d 398 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 17 301 1.4E-71 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme GBCGDNIH2_RS11860 2e07813cfd55be31fb7e807faf4ac11d 398 TIGRFAM TIGR01127 ilvA_1Cterm: threonine ammonia-lyase 21 391 3.4E-119 T 29-03-2018 IPR005789 Threonine dehydratase, catabolic GO:0004794|GO:0006567 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 GBCGDNIH2_RS11860 2e07813cfd55be31fb7e807faf4ac11d 398 Gene3D G3DSA:3.40.50.1100 27 137 1.7E-29 T 29-03-2018 GBCGDNIH2_RS11860 2e07813cfd55be31fb7e807faf4ac11d 398 Gene3D G3DSA:3.30.70.260 323 398 3.9E-10 T 29-03-2018 GBCGDNIH2_RS11860 2e07813cfd55be31fb7e807faf4ac11d 398 SUPERFAMILY SSF53686 4 348 2.1E-88 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme GBCGDNIH2_RS02900 2534140e5ef133c8ff1c7f778305e488 101 ProSitePatterns PS00527 Ribosomal protein S14 signature. 63 85 - T 29-03-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02900 2534140e5ef133c8ff1c7f778305e488 101 SUPERFAMILY SSF57716 2 101 9.27E-32 T 29-03-2018 GBCGDNIH2_RS02900 2534140e5ef133c8ff1c7f778305e488 101 Pfam PF00253 Ribosomal protein S14p/S29e 48 100 5.9E-22 T 29-03-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS02900 2534140e5ef133c8ff1c7f778305e488 101 Gene3D G3DSA:4.10.830.10 1 101 2.9E-28 T 29-03-2018 GBCGDNIH2_RS02900 2534140e5ef133c8ff1c7f778305e488 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 24.61 T 29-03-2018 IPR023036 Ribosomal protein S14, bacterial/plastid GBCGDNIH2_RS09670 d6ba68d17ab6455a33e3bcf12bd242aa 302 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 10 270 4.0E-44 T 29-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 GBCGDNIH2_RS09670 d6ba68d17ab6455a33e3bcf12bd242aa 302 Pfam PF08544 GHMP kinases C terminal 199 274 7.6E-10 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain GBCGDNIH2_RS09670 d6ba68d17ab6455a33e3bcf12bd242aa 302 PIRSF PIRSF010376 5 296 1.4E-71 T 29-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 GBCGDNIH2_RS09670 d6ba68d17ab6455a33e3bcf12bd242aa 302 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 6 296 29.891 T 29-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 GBCGDNIH2_RS09670 d6ba68d17ab6455a33e3bcf12bd242aa 302 Pfam PF00288 GHMP kinases N terminal domain 94 148 4.8E-7 T 29-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 GBCGDNIH2_RS09670 d6ba68d17ab6455a33e3bcf12bd242aa 302 Gene3D G3DSA:3.30.70.890 167 287 2.8E-24 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain GBCGDNIH2_RS09670 d6ba68d17ab6455a33e3bcf12bd242aa 302 Gene3D G3DSA:3.30.230.10 6 166 2.0E-36 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup GBCGDNIH2_RS09670 d6ba68d17ab6455a33e3bcf12bd242aa 302 SUPERFAMILY SSF55060 169 278 1.78E-23 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain GBCGDNIH2_RS09670 d6ba68d17ab6455a33e3bcf12bd242aa 302 SUPERFAMILY SSF54211 7 163 9.87E-33 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold GBCGDNIH2_RS06665 8174c1eef7f70bf4784a003d5a74c501 451 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 277 306 3.3E-4 T 29-03-2018 IPR001451 Hexapeptide repeat GBCGDNIH2_RS06665 8174c1eef7f70bf4784a003d5a74c501 451 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 385 417 1.1E-6 T 29-03-2018 IPR001451 Hexapeptide repeat GBCGDNIH2_RS06665 8174c1eef7f70bf4784a003d5a74c501 451 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 307 341 4.0E-6 T 29-03-2018 IPR001451 Hexapeptide repeat GBCGDNIH2_RS06665 8174c1eef7f70bf4784a003d5a74c501 451 SUPERFAMILY SSF51161 252 435 1.18E-46 T 29-03-2018 IPR011004 Trimeric LpxA-like GBCGDNIH2_RS06665 8174c1eef7f70bf4784a003d5a74c501 451 Gene3D G3DSA:3.90.550.10 4 257 1.8E-44 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS06665 8174c1eef7f70bf4784a003d5a74c501 451 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 11 442 36.568 T 29-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 GBCGDNIH2_RS06665 8174c1eef7f70bf4784a003d5a74c501 451 Gene3D G3DSA:2.160.10.10 258 429 5.1E-40 T 29-03-2018 GBCGDNIH2_RS06665 8174c1eef7f70bf4784a003d5a74c501 451 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 14 440 1.8E-139 T 29-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 GBCGDNIH2_RS06665 8174c1eef7f70bf4784a003d5a74c501 451 Pfam PF12804 MobA-like NTP transferase domain 14 134 1.1E-20 T 29-03-2018 IPR025877 MobA-like NTP transferase GBCGDNIH2_RS06665 8174c1eef7f70bf4784a003d5a74c501 451 SUPERFAMILY SSF53448 13 257 1.21E-50 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS12200 92edb5d8534ca8bed5ec869ffc7c7e0f 307 Gene3D G3DSA:2.30.130.10 242 307 5.0E-12 T 29-03-2018 IPR002478 PUA domain GO:0003723 GBCGDNIH2_RS12200 92edb5d8534ca8bed5ec869ffc7c7e0f 307 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 10 307 17.59 T 29-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 GBCGDNIH2_RS12200 92edb5d8534ca8bed5ec869ffc7c7e0f 307 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 181 240 2.1E-10 T 29-03-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 GBCGDNIH2_RS12200 92edb5d8534ca8bed5ec869ffc7c7e0f 307 SUPERFAMILY SSF55120 9 221 3.17E-70 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 GBCGDNIH2_RS12200 92edb5d8534ca8bed5ec869ffc7c7e0f 307 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 11 217 2.0E-60 T 29-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 GBCGDNIH2_RS12200 92edb5d8534ca8bed5ec869ffc7c7e0f 307 Pfam PF09157 Pseudouridine synthase II TruB, C-terminal 244 306 6.6E-7 T 29-03-2018 IPR015240 tRNA pseudouridine synthase II, TruB, subfamily 1, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 GBCGDNIH2_RS12200 92edb5d8534ca8bed5ec869ffc7c7e0f 307 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 32 180 2.5E-46 T 29-03-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 GBCGDNIH2_RS12200 92edb5d8534ca8bed5ec869ffc7c7e0f 307 Gene3D G3DSA:3.30.2350.10 9 225 5.7E-72 T 29-03-2018 GBCGDNIH2_RS05400 92d2f04500dd17a285e5654c86665aa0 839 Gene3D G3DSA:3.60.20.10 704 830 1.9E-10 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal GBCGDNIH2_RS05400 92d2f04500dd17a285e5654c86665aa0 839 Gene3D G3DSA:3.60.20.10 303 394 2.5E-25 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal GBCGDNIH2_RS05400 92d2f04500dd17a285e5654c86665aa0 839 SUPERFAMILY SSF56235 98 829 3.09E-195 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal GBCGDNIH2_RS05400 92d2f04500dd17a285e5654c86665aa0 839 Gene3D G3DSA:1.10.439.10 88 252 2.6E-48 T 29-03-2018 IPR023343 Penicillin amidase type, domain1 GO:0016811 GBCGDNIH2_RS05400 92d2f04500dd17a285e5654c86665aa0 839 PIRSF PIRSF001227 58 837 1.2E-164 T 29-03-2018 IPR014395 Penicillin/GL-7-ACA/AHL acylase GO:0016811 GBCGDNIH2_RS05400 92d2f04500dd17a285e5654c86665aa0 839 Pfam PF01804 Penicillin amidase 101 827 1.4E-192 T 29-03-2018 IPR002692 Penicillin/GL-7-ACA/AHL/aculeacin-A acylase GO:0016787|GO:0017000 GBCGDNIH2_RS05400 92d2f04500dd17a285e5654c86665aa0 839 Gene3D G3DSA:1.10.1400.10 596 703 7.2E-21 T 29-03-2018 GBCGDNIH2_RS05400 92d2f04500dd17a285e5654c86665aa0 839 Gene3D G3DSA:3.60.20.10 398 595 2.8E-41 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal GBCGDNIH2_RS00130 4189dffdf5de7ddb1ff8d1fcd8355c1d 205 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 11 201 43.253 T 29-03-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 GBCGDNIH2_RS00130 4189dffdf5de7ddb1ff8d1fcd8355c1d 205 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 13 197 1.3E-47 T 29-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 GBCGDNIH2_RS00130 4189dffdf5de7ddb1ff8d1fcd8355c1d 205 Pfam PF01725 Ham1 family 13 197 2.5E-50 T 29-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 GBCGDNIH2_RS00130 4189dffdf5de7ddb1ff8d1fcd8355c1d 205 Gene3D G3DSA:3.90.950.10 1 201 4.8E-72 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like GBCGDNIH2_RS00130 4189dffdf5de7ddb1ff8d1fcd8355c1d 205 SUPERFAMILY SSF52972 8 199 3.66E-63 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like GBCGDNIH2_RS09865 d48b2ff7487eec8e6f30cb89919bc997 265 SUPERFAMILY SSF55811 88 257 1.9E-11 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 GBCGDNIH2_RS09865 d48b2ff7487eec8e6f30cb89919bc997 265 Gene3D G3DSA:3.90.79.10 88 264 7.9E-10 T 29-03-2018 GBCGDNIH2_RS06260 7559d4170e99b4f07d753e105dc67e2a 175 SUPERFAMILY SSF46785 6 145 1.85E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS06260 7559d4170e99b4f07d753e105dc67e2a 175 Pfam PF01638 HxlR-like helix-turn-helix 20 104 2.3E-19 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type GBCGDNIH2_RS06260 7559d4170e99b4f07d753e105dc67e2a 175 Gene3D G3DSA:1.10.10.10 1 169 1.5E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS01340 42564db3632169a66f13756d6c90ba2f 409 Gene3D G3DSA:3.90.1260.10 166 359 9.2E-88 T 29-03-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 GBCGDNIH2_RS01340 42564db3632169a66f13756d6c90ba2f 409 Gene3D G3DSA:3.40.50.620 2 165 2.9E-27 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GBCGDNIH2_RS01340 42564db3632169a66f13756d6c90ba2f 409 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 120 131 - T 29-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 GBCGDNIH2_RS01340 42564db3632169a66f13756d6c90ba2f 409 Gene3D G3DSA:1.20.5.470 370 402 3.6E-12 T 29-03-2018 GBCGDNIH2_RS01340 42564db3632169a66f13756d6c90ba2f 409 SUPERFAMILY SSF69864 179 400 1.03E-89 T 29-03-2018 GBCGDNIH2_RS01340 42564db3632169a66f13756d6c90ba2f 409 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 12 20 - T 29-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 GBCGDNIH2_RS01340 42564db3632169a66f13756d6c90ba2f 409 SUPERFAMILY SSF52402 7 170 5.07E-46 T 29-03-2018 GBCGDNIH2_RS01340 42564db3632169a66f13756d6c90ba2f 409 TIGRFAM TIGR00032 argG: argininosuccinate synthase 8 398 1.7E-141 T 29-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 GBCGDNIH2_RS01340 42564db3632169a66f13756d6c90ba2f 409 Pfam PF00764 Arginosuccinate synthase 10 398 3.9E-153 T 29-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 GBCGDNIH2_RS01340 42564db3632169a66f13756d6c90ba2f 409 Hamap MF_00005 Argininosuccinate synthase [argG]. 6 404 52.376 T 29-03-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 GBCGDNIH2_RS08190 bb111bf7f6d623a0b37015be816c9099 681 SUPERFAMILY SSF54001 54 249 1.54E-29 T 29-03-2018 GBCGDNIH2_RS08190 bb111bf7f6d623a0b37015be816c9099 681 Gene3D G3DSA:3.90.70.10 180 253 4.7E-5 T 29-03-2018 GBCGDNIH2_RS08190 bb111bf7f6d623a0b37015be816c9099 681 Pfam PF00648 Calpain family cysteine protease 58 249 1.5E-16 T 29-03-2018 IPR001300 Peptidase C2, calpain, catalytic domain GO:0004198|GO:0005622|GO:0006508 Reactome: R-HSA-1474228 GBCGDNIH2_RS08190 bb111bf7f6d623a0b37015be816c9099 681 SMART SM00230 15 282 6.0E-4 T 29-03-2018 IPR001300 Peptidase C2, calpain, catalytic domain GO:0004198|GO:0005622|GO:0006508 Reactome: R-HSA-1474228 GBCGDNIH2_RS01610 9adb18a8403cdf5d47c123f82e29cdae 396 Gene3D G3DSA:3.40.50.1260 3 178 2.5E-69 T 29-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GBCGDNIH2_RS01610 9adb18a8403cdf5d47c123f82e29cdae 396 PRINTS PR00477 Phosphoglycerate kinase family signature 312 337 5.9E-75 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GBCGDNIH2_RS01610 9adb18a8403cdf5d47c123f82e29cdae 396 PRINTS PR00477 Phosphoglycerate kinase family signature 190 209 5.9E-75 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GBCGDNIH2_RS01610 9adb18a8403cdf5d47c123f82e29cdae 396 PRINTS PR00477 Phosphoglycerate kinase family signature 349 360 5.9E-75 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GBCGDNIH2_RS01610 9adb18a8403cdf5d47c123f82e29cdae 396 PRINTS PR00477 Phosphoglycerate kinase family signature 372 389 5.9E-75 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GBCGDNIH2_RS01610 9adb18a8403cdf5d47c123f82e29cdae 396 PRINTS PR00477 Phosphoglycerate kinase family signature 31 53 5.9E-75 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GBCGDNIH2_RS01610 9adb18a8403cdf5d47c123f82e29cdae 396 PRINTS PR00477 Phosphoglycerate kinase family signature 109 124 5.9E-75 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GBCGDNIH2_RS01610 9adb18a8403cdf5d47c123f82e29cdae 396 PRINTS PR00477 Phosphoglycerate kinase family signature 167 189 5.9E-75 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GBCGDNIH2_RS01610 9adb18a8403cdf5d47c123f82e29cdae 396 PRINTS PR00477 Phosphoglycerate kinase family signature 137 159 5.9E-75 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GBCGDNIH2_RS01610 9adb18a8403cdf5d47c123f82e29cdae 396 PRINTS PR00477 Phosphoglycerate kinase family signature 10 26 5.9E-75 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GBCGDNIH2_RS01610 9adb18a8403cdf5d47c123f82e29cdae 396 PIRSF PIRSF000724 1 396 6.6E-140 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GBCGDNIH2_RS01610 9adb18a8403cdf5d47c123f82e29cdae 396 Gene3D G3DSA:3.40.50.1260 179 384 1.4E-69 T 29-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GBCGDNIH2_RS01610 9adb18a8403cdf5d47c123f82e29cdae 396 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 5 396 38.906 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GBCGDNIH2_RS01610 9adb18a8403cdf5d47c123f82e29cdae 396 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 15 25 - T 29-03-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GBCGDNIH2_RS01610 9adb18a8403cdf5d47c123f82e29cdae 396 SUPERFAMILY SSF53748 1 395 8.13E-147 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GBCGDNIH2_RS01610 9adb18a8403cdf5d47c123f82e29cdae 396 Pfam PF00162 Phosphoglycerate kinase 8 386 1.1E-143 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GBCGDNIH2_RS10050 73409cce630cece7cd0efb4ca8810bf2 374 Pfam PF13186 Iron-sulfur cluster-binding domain 238 304 9.0E-8 T 29-03-2018 IPR023885 4Fe4S-binding SPASM domain GBCGDNIH2_RS10050 73409cce630cece7cd0efb4ca8810bf2 374 SUPERFAMILY SSF102114 6 313 3.53E-72 T 29-03-2018 GBCGDNIH2_RS10050 73409cce630cece7cd0efb4ca8810bf2 374 PIRSF PIRSF037420 1 349 3.0E-115 T 29-03-2018 GBCGDNIH2_RS10050 73409cce630cece7cd0efb4ca8810bf2 374 Hamap MF_00660 Coenzyme PQQ synthesis protein E [pqqE]. 1 371 179.298 T 29-03-2018 IPR011843 Coenzyme PQQ biosynthesis protein E, bacteria GO:0018189|GO:0051539 GBCGDNIH2_RS10050 73409cce630cece7cd0efb4ca8810bf2 374 SMART SM00729 8 208 1.6E-4 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 GBCGDNIH2_RS10050 73409cce630cece7cd0efb4ca8810bf2 374 Gene3D G3DSA:3.20.20.70 5 294 4.8E-43 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS10050 73409cce630cece7cd0efb4ca8810bf2 374 Pfam PF04055 Radical SAM superfamily 14 168 4.5E-26 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 GBCGDNIH2_RS10050 73409cce630cece7cd0efb4ca8810bf2 374 Pfam PF13353 4Fe-4S single cluster domain 15 100 1.3E-7 T 29-03-2018 GBCGDNIH2_RS10050 73409cce630cece7cd0efb4ca8810bf2 374 TIGRFAM TIGR02109 PQQ_syn_pqqE: coenzyme PQQ biosynthesis enzyme PqqE 3 350 1.9E-169 T 29-03-2018 IPR011843 Coenzyme PQQ biosynthesis protein E, bacteria GO:0018189|GO:0051539 GBCGDNIH2_RS10050 73409cce630cece7cd0efb4ca8810bf2 374 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 14 25 - T 29-03-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 Reactome: R-HSA-947581 GBCGDNIH2_RS10050 73409cce630cece7cd0efb4ca8810bf2 374 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 241 331 7.1E-8 T 29-03-2018 IPR023885 4Fe4S-binding SPASM domain GBCGDNIH2_RS12715 9f1a1cd90e83d939f51dd6dc2ac8c3e6 476 Gene3D G3DSA:2.40.10.170 1 77 3.2E-29 T 29-03-2018 GBCGDNIH2_RS12715 9f1a1cd90e83d939f51dd6dc2ac8c3e6 476 SMART SM00382 144 331 4.4E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS12715 9f1a1cd90e83d939f51dd6dc2ac8c3e6 476 Hamap MF_01347 ATP synthase subunit beta [atpB]. 4 472 57.644 T 29-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 GBCGDNIH2_RS12715 9f1a1cd90e83d939f51dd6dc2ac8c3e6 476 SUPERFAMILY SSF47917 357 472 7.32E-53 T 29-03-2018 GBCGDNIH2_RS12715 9f1a1cd90e83d939f51dd6dc2ac8c3e6 476 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 132 354 1.9E-61 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 GBCGDNIH2_RS12715 9f1a1cd90e83d939f51dd6dc2ac8c3e6 476 PIRSF PIRSF039072 1 476 1.1E-274 T 29-03-2018 GBCGDNIH2_RS12715 9f1a1cd90e83d939f51dd6dc2ac8c3e6 476 SUPERFAMILY SSF50615 4 77 2.88E-23 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 GBCGDNIH2_RS12715 9f1a1cd90e83d939f51dd6dc2ac8c3e6 476 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 345 354 - T 29-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 GBCGDNIH2_RS12715 9f1a1cd90e83d939f51dd6dc2ac8c3e6 476 SUPERFAMILY SSF52540 79 359 8.08E-88 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS12715 9f1a1cd90e83d939f51dd6dc2ac8c3e6 476 Gene3D G3DSA:1.10.1140.10 360 470 1.4E-42 T 29-03-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 GBCGDNIH2_RS12715 9f1a1cd90e83d939f51dd6dc2ac8c3e6 476 Gene3D G3DSA:3.40.50.300 78 359 6.6E-92 T 29-03-2018 GBCGDNIH2_RS12715 9f1a1cd90e83d939f51dd6dc2ac8c3e6 476 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 9 75 7.9E-20 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 GBCGDNIH2_RS12715 9f1a1cd90e83d939f51dd6dc2ac8c3e6 476 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 6 472 3.4E-250 T 29-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 GBCGDNIH2_RS05455 206cd1ba97a635b03ac252900a31641a 157 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 155 84.464 T 29-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 GBCGDNIH2_RS05455 206cd1ba97a635b03ac252900a31641a 157 Pfam PF03477 ATP cone domain 50 136 6.2E-18 T 29-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 GBCGDNIH2_RS05455 206cd1ba97a635b03ac252900a31641a 157 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 141 1.0E-54 T 29-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 GBCGDNIH2_RS08450 1d4a82b80eb96eac35d433361ec86597 714 Gene3D G3DSA:2.40.180.10 35 403 1.3E-157 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 GBCGDNIH2_RS08450 1d4a82b80eb96eac35d433361ec86597 714 ProSitePatterns PS00438 Catalase proximal active site signature. 84 100 - T 29-03-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 GBCGDNIH2_RS08450 1d4a82b80eb96eac35d433361ec86597 714 PRINTS PR00067 Catalase signature 365 391 3.4E-65 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 GBCGDNIH2_RS08450 1d4a82b80eb96eac35d433361ec86597 714 PRINTS PR00067 Catalase signature 333 360 3.4E-65 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 GBCGDNIH2_RS08450 1d4a82b80eb96eac35d433361ec86597 714 PRINTS PR00067 Catalase signature 164 182 3.4E-65 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 GBCGDNIH2_RS08450 1d4a82b80eb96eac35d433361ec86597 714 PRINTS PR00067 Catalase signature 61 84 3.4E-65 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 GBCGDNIH2_RS08450 1d4a82b80eb96eac35d433361ec86597 714 PRINTS PR00067 Catalase signature 124 142 3.4E-65 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 GBCGDNIH2_RS08450 1d4a82b80eb96eac35d433361ec86597 714 PRINTS PR00067 Catalase signature 145 162 3.4E-65 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 GBCGDNIH2_RS08450 1d4a82b80eb96eac35d433361ec86597 714 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 378 386 - T 29-03-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 GBCGDNIH2_RS08450 1d4a82b80eb96eac35d433361ec86597 714 SMART SM01060 48 436 2.2E-263 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 GBCGDNIH2_RS08450 1d4a82b80eb96eac35d433361ec86597 714 Pfam PF00199 Catalase 48 432 2.3E-175 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 GBCGDNIH2_RS08450 1d4a82b80eb96eac35d433361ec86597 714 SUPERFAMILY SSF56634 39 534 6.41E-210 T 29-03-2018 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 GBCGDNIH2_RS08450 1d4a82b80eb96eac35d433361ec86597 714 Gene3D G3DSA:3.40.50.880 561 713 9.0E-14 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like GBCGDNIH2_RS08450 1d4a82b80eb96eac35d433361ec86597 714 Pfam PF06628 Catalase-related immune-responsive 463 526 3.7E-21 T 29-03-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 GBCGDNIH2_RS08450 1d4a82b80eb96eac35d433361ec86597 714 PIRSF PIRSF038927 33 714 7.4E-295 T 29-03-2018 IPR024712 Catalase, mono-functional, haem-containing, clade 2 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 GBCGDNIH2_RS08450 1d4a82b80eb96eac35d433361ec86597 714 SUPERFAMILY SSF52317 562 708 3.66E-13 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like GBCGDNIH2_RS09515 58b357a10df6b6637244f3ed87aa70c5 407 Pfam PF01464 Transglycosylase SLT domain 83 190 7.2E-20 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 GBCGDNIH2_RS09515 58b357a10df6b6637244f3ed87aa70c5 407 SUPERFAMILY SSF53955 64 206 2.38E-35 T 29-03-2018 IPR023346 Lysozyme-like domain GBCGDNIH2_RS09515 58b357a10df6b6637244f3ed87aa70c5 407 Pfam PF05036 Sporulation related domain 327 400 6.1E-13 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 GBCGDNIH2_RS09515 58b357a10df6b6637244f3ed87aa70c5 407 Gene3D G3DSA:3.30.70.1070 328 403 9.4E-11 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 GBCGDNIH2_RS09515 58b357a10df6b6637244f3ed87aa70c5 407 Gene3D G3DSA:1.10.530.10 43 211 2.5E-36 T 29-03-2018 GBCGDNIH2_RS01125 4e6681961adccd9c87fed1200dabe5e3 246 Gene3D G3DSA:3.10.290.10 1 62 2.1E-14 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 GBCGDNIH2_RS01125 4e6681961adccd9c87fed1200dabe5e3 246 SUPERFAMILY SSF53335 56 244 4.32E-26 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GBCGDNIH2_RS01125 4e6681961adccd9c87fed1200dabe5e3 246 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 5 238 3.1E-65 T 29-03-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 GBCGDNIH2_RS01125 4e6681961adccd9c87fed1200dabe5e3 246 PIRSF PIRSF005578 1 246 1.2E-96 T 29-03-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 GBCGDNIH2_RS01125 4e6681961adccd9c87fed1200dabe5e3 246 Pfam PF01728 FtsJ-like methyltransferase 60 242 3.5E-20 T 29-03-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 GBCGDNIH2_RS01125 4e6681961adccd9c87fed1200dabe5e3 246 Gene3D G3DSA:3.40.50.150 63 246 1.4E-53 T 29-03-2018 GBCGDNIH2_RS01125 4e6681961adccd9c87fed1200dabe5e3 246 SUPERFAMILY SSF55174 4 68 1.62E-7 T 29-03-2018 GBCGDNIH2_RS12660 f24adc04d3a00a66a1f252d7b8369fec 177 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 2 175 4.8E-60 T 29-03-2018 IPR024455 Phage capsid GBCGDNIH2_RS12660 f24adc04d3a00a66a1f252d7b8369fec 177 Pfam PF05065 Phage capsid family 2 175 2.0E-46 T 29-03-2018 IPR024455 Phage capsid GBCGDNIH2_RS12660 f24adc04d3a00a66a1f252d7b8369fec 177 SUPERFAMILY SSF56563 1 175 5.49E-41 T 29-03-2018 GBCGDNIH2_RS12660 f24adc04d3a00a66a1f252d7b8369fec 177 Gene3D G3DSA:3.30.2320.10 33 144 5.8E-27 T 29-03-2018 GBCGDNIH2_RS09345 c54da149698a686f0a7c9fcbbde23edc 328 Gene3D G3DSA:3.40.50.1820 23 328 5.8E-44 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS09345 c54da149698a686f0a7c9fcbbde23edc 328 SUPERFAMILY SSF53474 88 323 9.76E-51 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS09345 c54da149698a686f0a7c9fcbbde23edc 328 Pfam PF07859 alpha/beta hydrolase fold 107 303 1.0E-50 T 29-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 GBCGDNIH2_RS03255 8e4f4f991574b170d9ace2dd6e49c2b9 202 Pfam PF03567 Sulfotransferase family 18 135 2.9E-6 T 29-03-2018 IPR005331 Sulfotransferase GO:0008146|GO:0016021 GBCGDNIH2_RS00550 882a57e4c867aa248c2ded3adfc6c818 283 Pfam PF13369 Transglutaminase-like superfamily 67 201 1.8E-28 T 29-03-2018 IPR032698 Protein SirB1, N-terminal Reactome: R-HSA-8951664|Reactome: R-HSA-983168 GBCGDNIH2_RS00550 882a57e4c867aa248c2ded3adfc6c818 283 Gene3D G3DSA:1.25.40.10 10 283 3.9E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS00550 882a57e4c867aa248c2ded3adfc6c818 283 Pfam PF13371 Tetratricopeptide repeat 204 275 5.3E-18 T 29-03-2018 GBCGDNIH2_RS00550 882a57e4c867aa248c2ded3adfc6c818 283 SUPERFAMILY SSF48452 185 277 4.22E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS02970 881af7ac2e8fd05a87f7beda87b394af 452 SUPERFAMILY SSF52540 26 236 2.34E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS02970 881af7ac2e8fd05a87f7beda87b394af 452 SUPERFAMILY SSF48019 260 446 2.44E-67 T 29-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 GBCGDNIH2_RS02970 881af7ac2e8fd05a87f7beda87b394af 452 SMART SM00382 65 181 6.2E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS02970 881af7ac2e8fd05a87f7beda87b394af 452 Pfam PF16193 AAA C-terminal domain 200 274 1.1E-18 T 29-03-2018 IPR032423 AAA C-terminal domain GBCGDNIH2_RS02970 881af7ac2e8fd05a87f7beda87b394af 452 Pfam PF12002 MgsA AAA+ ATPase C terminal 275 443 7.9E-62 T 29-03-2018 IPR021886 MgsA AAA+ ATPase C-terminal GBCGDNIH2_RS02970 881af7ac2e8fd05a87f7beda87b394af 452 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 69 177 3.2E-15 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 GBCGDNIH2_RS02970 881af7ac2e8fd05a87f7beda87b394af 452 Gene3D G3DSA:1.20.272.10 259 353 3.3E-37 T 29-03-2018 GBCGDNIH2_RS02970 881af7ac2e8fd05a87f7beda87b394af 452 Gene3D G3DSA:1.10.8.60 170 248 1.7E-19 T 29-03-2018 GBCGDNIH2_RS02970 881af7ac2e8fd05a87f7beda87b394af 452 Gene3D G3DSA:3.40.50.300 20 169 5.8E-30 T 29-03-2018 GBCGDNIH2_RS02970 881af7ac2e8fd05a87f7beda87b394af 452 Gene3D G3DSA:1.10.3710.10 355 451 8.0E-27 T 29-03-2018 GBCGDNIH2_RS01885 5fc28469c8369b6332626a0e34d35d52 422 Pfam PF13660 Domain of unknown function (DUF4147) 12 232 5.6E-83 T 29-03-2018 IPR025286 MOFRL-associated domain Reactome: R-HSA-70350 GBCGDNIH2_RS01885 5fc28469c8369b6332626a0e34d35d52 422 Pfam PF05161 MOFRL family 308 415 8.0E-37 T 29-03-2018 IPR007835 MOFRL domain Reactome: R-HSA-70350 GBCGDNIH2_RS01885 5fc28469c8369b6332626a0e34d35d52 422 Gene3D G3DSA:3.40.50.10180 13 242 9.3E-87 T 29-03-2018 GBCGDNIH2_RS01885 5fc28469c8369b6332626a0e34d35d52 422 SUPERFAMILY SSF82544 9 421 7.59E-145 T 29-03-2018 GBCGDNIH2_RS01885 5fc28469c8369b6332626a0e34d35d52 422 Gene3D G3DSA:3.40.1480.10 243 422 4.9E-61 T 29-03-2018 IPR007835 MOFRL domain Reactome: R-HSA-70350 GBCGDNIH2_RS11775 14c5d207e50f3f70592578c5baeacd0c 316 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 19 156 3.4E-50 T 29-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 GBCGDNIH2_RS11775 14c5d207e50f3f70592578c5baeacd0c 316 Gene3D G3DSA:3.40.50.1370 17 172 2.9E-62 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 GBCGDNIH2_RS11775 14c5d207e50f3f70592578c5baeacd0c 316 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 19 312 6.3E-114 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 GBCGDNIH2_RS11775 14c5d207e50f3f70592578c5baeacd0c 316 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 265 274 6.5E-29 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 GBCGDNIH2_RS11775 14c5d207e50f3f70592578c5baeacd0c 316 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 143 154 6.5E-29 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 GBCGDNIH2_RS11775 14c5d207e50f3f70592578c5baeacd0c 316 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 277 300 6.5E-29 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 GBCGDNIH2_RS11775 14c5d207e50f3f70592578c5baeacd0c 316 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 61 80 6.5E-29 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 GBCGDNIH2_RS11775 14c5d207e50f3f70592578c5baeacd0c 316 PRINTS PR00102 Ornithine carbamoyltransferase signature 132 146 9.7E-30 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 GBCGDNIH2_RS11775 14c5d207e50f3f70592578c5baeacd0c 316 PRINTS PR00102 Ornithine carbamoyltransferase signature 92 105 9.7E-30 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 GBCGDNIH2_RS11775 14c5d207e50f3f70592578c5baeacd0c 316 PRINTS PR00102 Ornithine carbamoyltransferase signature 231 241 9.7E-30 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 GBCGDNIH2_RS11775 14c5d207e50f3f70592578c5baeacd0c 316 PRINTS PR00102 Ornithine carbamoyltransferase signature 59 73 9.7E-30 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 GBCGDNIH2_RS11775 14c5d207e50f3f70592578c5baeacd0c 316 PRINTS PR00102 Ornithine carbamoyltransferase signature 291 302 9.7E-30 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 GBCGDNIH2_RS11775 14c5d207e50f3f70592578c5baeacd0c 316 Gene3D G3DSA:3.40.50.1370 173 314 9.2E-50 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 GBCGDNIH2_RS11775 14c5d207e50f3f70592578c5baeacd0c 316 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 61 68 - T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 GBCGDNIH2_RS11775 14c5d207e50f3f70592578c5baeacd0c 316 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 163 310 8.9E-50 T 29-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 GBCGDNIH2_RS11775 14c5d207e50f3f70592578c5baeacd0c 316 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 18 313 75.502 T 29-03-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 GBCGDNIH2_RS11775 14c5d207e50f3f70592578c5baeacd0c 316 SUPERFAMILY SSF53671 18 313 1.31E-107 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 GBCGDNIH2_RS03145 60078afa80a4cfc24fe7ed031ba00817 590 ProSitePatterns PS01128 Shikimate kinase signature. 107 132 - T 29-03-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 GBCGDNIH2_RS03145 60078afa80a4cfc24fe7ed031ba00817 590 SUPERFAMILY SSF52540 51 220 4.69E-26 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS03145 60078afa80a4cfc24fe7ed031ba00817 590 Hamap MF_00109 Shikimate kinase [aroK]. 51 216 28.051 T 29-03-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 GBCGDNIH2_RS03145 60078afa80a4cfc24fe7ed031ba00817 590 SUPERFAMILY SSF56796 224 584 1.19E-102 T 29-03-2018 GBCGDNIH2_RS03145 60078afa80a4cfc24fe7ed031ba00817 590 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 222 585 39.645 T 29-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 GBCGDNIH2_RS03145 60078afa80a4cfc24fe7ed031ba00817 590 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 233 582 1.0E-106 T 29-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 GBCGDNIH2_RS03145 60078afa80a4cfc24fe7ed031ba00817 590 Gene3D G3DSA:3.40.50.1970 226 393 5.7E-50 T 29-03-2018 GBCGDNIH2_RS03145 60078afa80a4cfc24fe7ed031ba00817 590 Gene3D G3DSA:1.20.1090.10 394 588 2.5E-55 T 29-03-2018 GBCGDNIH2_RS03145 60078afa80a4cfc24fe7ed031ba00817 590 PRINTS PR01100 Shikimate kinase family signature 78 91 4.1E-16 T 29-03-2018 GBCGDNIH2_RS03145 60078afa80a4cfc24fe7ed031ba00817 590 PRINTS PR01100 Shikimate kinase family signature 145 162 4.1E-16 T 29-03-2018 GBCGDNIH2_RS03145 60078afa80a4cfc24fe7ed031ba00817 590 PRINTS PR01100 Shikimate kinase family signature 54 69 4.1E-16 T 29-03-2018 GBCGDNIH2_RS03145 60078afa80a4cfc24fe7ed031ba00817 590 PRINTS PR01100 Shikimate kinase family signature 106 114 4.1E-16 T 29-03-2018 GBCGDNIH2_RS03145 60078afa80a4cfc24fe7ed031ba00817 590 PRINTS PR01100 Shikimate kinase family signature 124 133 4.1E-16 T 29-03-2018 GBCGDNIH2_RS03145 60078afa80a4cfc24fe7ed031ba00817 590 Pfam PF01202 Shikimate kinase 60 214 9.2E-46 T 29-03-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 GBCGDNIH2_RS03145 60078afa80a4cfc24fe7ed031ba00817 590 Gene3D G3DSA:3.40.50.300 51 225 3.7E-31 T 29-03-2018 GBCGDNIH2_RS03145 60078afa80a4cfc24fe7ed031ba00817 590 Pfam PF01761 3-dehydroquinate synthase 288 552 2.2E-93 T 29-03-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 GBCGDNIH2_RS09485 ba7a0088bc0a3719b3fe66a37db6cbcb 264 PIRSF PIRSF029730 11 261 2.2E-92 T 29-03-2018 IPR011227 Uncharacterised conserved protein UCP029730 GBCGDNIH2_RS09485 ba7a0088bc0a3719b3fe66a37db6cbcb 264 Gene3D G3DSA:3.40.630.40 23 263 1.4E-60 T 29-03-2018 GBCGDNIH2_RS09485 ba7a0088bc0a3719b3fe66a37db6cbcb 264 SUPERFAMILY SSF53187 20 258 3.45E-71 T 29-03-2018 GBCGDNIH2_RS09485 ba7a0088bc0a3719b3fe66a37db6cbcb 264 Pfam PF05013 N-formylglutamate amidohydrolase 34 238 3.5E-45 T 29-03-2018 IPR007709 N-formylglutamate amidohydrolase GBCGDNIH2_RS11870 9e3e18ffb1074089ff4cd219ea36b57e 441 Pfam PF00083 Sugar (and other) transporter 29 233 4.3E-23 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 GBCGDNIH2_RS11870 9e3e18ffb1074089ff4cd219ea36b57e 441 SUPERFAMILY SSF103473 25 438 3.01E-61 T 29-03-2018 IPR020846 Major facilitator superfamily domain GBCGDNIH2_RS11870 9e3e18ffb1074089ff4cd219ea36b57e 441 Pfam PF07690 Major Facilitator Superfamily 264 435 1.4E-10 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 GBCGDNIH2_RS11870 9e3e18ffb1074089ff4cd219ea36b57e 441 ProSitePatterns PS00216 Sugar transport proteins signature 1. 309 324 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 GBCGDNIH2_RS11870 9e3e18ffb1074089ff4cd219ea36b57e 441 Gene3D G3DSA:1.20.1250.20 25 241 2.6E-21 T 29-03-2018 GBCGDNIH2_RS11870 9e3e18ffb1074089ff4cd219ea36b57e 441 Gene3D G3DSA:1.20.1250.20 251 441 8.5E-22 T 29-03-2018 GBCGDNIH2_RS03445 c1a9ac28a6c407351f0a2e0b6cde57f5 890 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 307 322 3.6E-8 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 GBCGDNIH2_RS03445 c1a9ac28a6c407351f0a2e0b6cde57f5 890 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 271 281 3.6E-8 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 GBCGDNIH2_RS03445 c1a9ac28a6c407351f0a2e0b6cde57f5 890 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 189 204 3.6E-8 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 GBCGDNIH2_RS03445 c1a9ac28a6c407351f0a2e0b6cde57f5 890 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 326 338 3.6E-8 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 GBCGDNIH2_RS03445 c1a9ac28a6c407351f0a2e0b6cde57f5 890 TIGRFAM TIGR02414 pepN_proteo: aminopeptidase N 22 889 0.0 T 29-03-2018 IPR012779 Peptidase M1, alanyl aminopeptidase GO:0008270 GBCGDNIH2_RS03445 c1a9ac28a6c407351f0a2e0b6cde57f5 890 Gene3D G3DSA:1.25.50.10 563 889 4.8E-116 T 29-03-2018 IPR024601 Peptidase M1, alanyl aminopeptidase, C-terminal GBCGDNIH2_RS03445 c1a9ac28a6c407351f0a2e0b6cde57f5 890 Pfam PF17432 Domain of unknown function (DUF3458_C) ARM repeats 565 889 7.1E-111 T 29-03-2018 IPR024601 Peptidase M1, alanyl aminopeptidase, C-terminal GBCGDNIH2_RS03445 c1a9ac28a6c407351f0a2e0b6cde57f5 890 Pfam PF01433 Peptidase family M1 domain 222 452 2.1E-57 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 GBCGDNIH2_RS03445 c1a9ac28a6c407351f0a2e0b6cde57f5 890 Pfam PF11940 Domain of unknown function (DUF3458) Ig-like fold 457 560 1.1E-29 T 29-03-2018 IPR035414 Peptidase M1, alanyl aminopeptidase, Ig-like fold GBCGDNIH2_RS03445 c1a9ac28a6c407351f0a2e0b6cde57f5 890 Gene3D G3DSA:2.60.40.1730 25 206 6.2E-29 T 29-03-2018 GBCGDNIH2_RS03445 c1a9ac28a6c407351f0a2e0b6cde57f5 890 SUPERFAMILY SSF55486 217 463 2.56E-78 T 29-03-2018 GBCGDNIH2_RS03445 c1a9ac28a6c407351f0a2e0b6cde57f5 890 Gene3D G3DSA:1.10.390.10 293 456 1.1E-53 T 29-03-2018 GBCGDNIH2_RS03445 c1a9ac28a6c407351f0a2e0b6cde57f5 890 SUPERFAMILY SSF63737 18 206 4.58E-41 T 29-03-2018 GBCGDNIH2_RS11375 d273d1874dfaea1883482cb348340cbe 108 Pfam PF06108 Protein of unknown function (DUF952) 11 98 6.3E-23 T 29-03-2018 IPR009297 Protein of unknown function DUF952 GBCGDNIH2_RS11375 d273d1874dfaea1883482cb348340cbe 108 SUPERFAMILY SSF56399 7 104 2.13E-25 T 29-03-2018 GBCGDNIH2_RS05370 247d70c591160d5d7de132e46a04ceca 252 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 28 44 2.1E-25 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 GBCGDNIH2_RS05370 247d70c591160d5d7de132e46a04ceca 252 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 98 110 2.1E-25 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 GBCGDNIH2_RS05370 247d70c591160d5d7de132e46a04ceca 252 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 183 202 2.1E-25 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 GBCGDNIH2_RS05370 247d70c591160d5d7de132e46a04ceca 252 SUPERFAMILY SSF51306 26 250 5.75E-61 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C GBCGDNIH2_RS05370 247d70c591160d5d7de132e46a04ceca 252 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 12 226 1.6E-49 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 GBCGDNIH2_RS05370 247d70c591160d5d7de132e46a04ceca 252 Gene3D G3DSA:2.10.109.10 25 247 3.3E-55 T 29-03-2018 GBCGDNIH2_RS05370 247d70c591160d5d7de132e46a04ceca 252 Pfam PF00717 Peptidase S24-like 35 121 2.0E-19 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C GBCGDNIH2_RS05370 247d70c591160d5d7de132e46a04ceca 252 ProSitePatterns PS00501 Signal peptidases I serine active site. 37 44 - T 29-03-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 GBCGDNIH2_RS05370 247d70c591160d5d7de132e46a04ceca 252 ProSitePatterns PS00760 Signal peptidases I lysine active site. 100 112 - T 29-03-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 GBCGDNIH2_RS03885 3d613d8f64b41391fea6777bbb693e95 212 Gene3D G3DSA:1.10.10.10 120 206 7.0E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS03885 3d613d8f64b41391fea6777bbb693e95 212 Pfam PF04542 Sigma-70 region 2 52 119 5.1E-15 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GBCGDNIH2_RS03885 3d613d8f64b41391fea6777bbb693e95 212 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 72 103 - T 29-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GBCGDNIH2_RS03885 3d613d8f64b41391fea6777bbb693e95 212 SUPERFAMILY SSF88946 28 126 3.53E-20 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GBCGDNIH2_RS03885 3d613d8f64b41391fea6777bbb693e95 212 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 50 203 5.3E-21 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GBCGDNIH2_RS03885 3d613d8f64b41391fea6777bbb693e95 212 Gene3D G3DSA:1.10.1740.10 28 119 4.7E-19 T 29-03-2018 GBCGDNIH2_RS03885 3d613d8f64b41391fea6777bbb693e95 212 Pfam PF08281 Sigma-70, region 4 149 198 3.6E-12 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GBCGDNIH2_RS03885 3d613d8f64b41391fea6777bbb693e95 212 SUPERFAMILY SSF88659 142 202 1.77E-11 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GBCGDNIH2_RS02115 fe42c129c9b3b8a8bd7f295dce99d8b9 585 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 121 203 3.4E-35 T 29-03-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202|KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 GBCGDNIH2_RS02115 fe42c129c9b3b8a8bd7f295dce99d8b9 585 Gene3D G3DSA:3.40.50.2300 2 99 5.5E-4 T 29-03-2018 GBCGDNIH2_RS02115 fe42c129c9b3b8a8bd7f295dce99d8b9 585 SUPERFAMILY SSF52794 119 218 2.09E-34 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 GBCGDNIH2_RS02115 fe42c129c9b3b8a8bd7f295dce99d8b9 585 Gene3D G3DSA:3.40.50.2300 119 217 6.2E-36 T 29-03-2018 GBCGDNIH2_RS02115 fe42c129c9b3b8a8bd7f295dce99d8b9 585 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 241 576 7.4E-133 T 29-03-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 GBCGDNIH2_RS02115 fe42c129c9b3b8a8bd7f295dce99d8b9 585 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 122 211 7.7E-17 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 GBCGDNIH2_RS02830 b065d3e5d5e5bc392dc4f840fbd3a2f8 102 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 8.2E-38 T 29-03-2018 IPR027486 Ribosomal protein S10 domain GBCGDNIH2_RS02830 b065d3e5d5e5bc392dc4f840fbd3a2f8 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 29-03-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02830 b065d3e5d5e5bc392dc4f840fbd3a2f8 102 SUPERFAMILY SSF54999 6 102 5.89E-40 T 29-03-2018 IPR027486 Ribosomal protein S10 domain GBCGDNIH2_RS02830 b065d3e5d5e5bc392dc4f840fbd3a2f8 102 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 2.8E-18 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02830 b065d3e5d5e5bc392dc4f840fbd3a2f8 102 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 2.8E-18 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02830 b065d3e5d5e5bc392dc4f840fbd3a2f8 102 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 2.8E-18 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02830 b065d3e5d5e5bc392dc4f840fbd3a2f8 102 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 4.8E-47 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02830 b065d3e5d5e5bc392dc4f840fbd3a2f8 102 SMART SM01403 7 101 3.2E-60 T 29-03-2018 IPR027486 Ribosomal protein S10 domain GBCGDNIH2_RS02830 b065d3e5d5e5bc392dc4f840fbd3a2f8 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 27.699 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02830 b065d3e5d5e5bc392dc4f840fbd3a2f8 102 Gene3D G3DSA:3.30.70.600 3 102 2.9E-39 T 29-03-2018 IPR027486 Ribosomal protein S10 domain GBCGDNIH2_RS02305 dd88a4c17670ef8c37e7102df1182dc4 872 SUPERFAMILY SSF51206 701 822 4.71E-24 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like GBCGDNIH2_RS02305 dd88a4c17670ef8c37e7102df1182dc4 872 Gene3D G3DSA:2.60.120.10 696 829 3.0E-23 T 29-03-2018 IPR014710 RmlC-like jelly roll fold GBCGDNIH2_RS02305 dd88a4c17670ef8c37e7102df1182dc4 872 Pfam PF00999 Sodium/hydrogen exchanger family 14 418 1.1E-44 T 29-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 GBCGDNIH2_RS02305 dd88a4c17670ef8c37e7102df1182dc4 872 SMART SM00100 708 820 4.3E-15 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain GBCGDNIH2_RS02305 dd88a4c17670ef8c37e7102df1182dc4 872 Pfam PF00027 Cyclic nucleotide-binding domain 731 807 2.2E-14 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain GBCGDNIH2_RS09005 dc1212120b44567d2d39cc049edaccfb 318 Gene3D G3DSA:3.40.50.720 41 183 2.5E-19 T 29-03-2018 GBCGDNIH2_RS09005 dc1212120b44567d2d39cc049edaccfb 318 Pfam PF16363 GDP-mannose 4,6 dehydratase 43 302 6.1E-39 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS09005 dc1212120b44567d2d39cc049edaccfb 318 SUPERFAMILY SSF51735 6 313 9.38E-62 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS09005 dc1212120b44567d2d39cc049edaccfb 318 Gene3D G3DSA:3.40.50.720 3 38 0.006 T 29-03-2018 GBCGDNIH2_RS09005 dc1212120b44567d2d39cc049edaccfb 318 Gene3D G3DSA:3.90.25.10 184 314 2.8E-30 T 29-03-2018 GBCGDNIH2_RS08490 b4bd117347e76d65dad1a1f2ae69333b 575 Gene3D G3DSA:4.10.450.10 51 107 3.6E-25 T 29-03-2018 GBCGDNIH2_RS08490 b4bd117347e76d65dad1a1f2ae69333b 575 TIGRFAM TIGR01810 betA: choline dehydrogenase 8 544 2.5E-274 T 29-03-2018 IPR011533 Oxygen-dependent choline dehydrogenase GO:0008812|GO:0019285 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494 GBCGDNIH2_RS08490 b4bd117347e76d65dad1a1f2ae69333b 575 Pfam PF00732 GMC oxidoreductase 7 307 5.0E-91 T 29-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 GBCGDNIH2_RS08490 b4bd117347e76d65dad1a1f2ae69333b 575 Gene3D G3DSA:3.30.560.10 108 497 1.7E-92 T 29-03-2018 GBCGDNIH2_RS08490 b4bd117347e76d65dad1a1f2ae69333b 575 Pfam PF05199 GMC oxidoreductase 400 534 8.5E-40 T 29-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 GBCGDNIH2_RS08490 b4bd117347e76d65dad1a1f2ae69333b 575 SUPERFAMILY SSF54373 302 484 2.55E-60 T 29-03-2018 GBCGDNIH2_RS08490 b4bd117347e76d65dad1a1f2ae69333b 575 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 266 280 - T 29-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 GBCGDNIH2_RS08490 b4bd117347e76d65dad1a1f2ae69333b 575 Gene3D G3DSA:2.60.40.1180 11 50 0.0013 T 29-03-2018 GBCGDNIH2_RS08490 b4bd117347e76d65dad1a1f2ae69333b 575 Hamap MF_00750 Oxygen-dependent choline dehydrogenase [betA]. 5 561 60.435 T 29-03-2018 IPR011533 Oxygen-dependent choline dehydrogenase GO:0008812|GO:0019285 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494 GBCGDNIH2_RS08490 b4bd117347e76d65dad1a1f2ae69333b 575 SUPERFAMILY SSF51905 5 300 1.21E-83 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS08490 b4bd117347e76d65dad1a1f2ae69333b 575 SUPERFAMILY SSF51905 483 543 1.21E-83 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS08490 b4bd117347e76d65dad1a1f2ae69333b 575 PIRSF PIRSF000137 1 544 4.2E-133 T 29-03-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 GBCGDNIH2_RS08490 b4bd117347e76d65dad1a1f2ae69333b 575 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 86 109 - T 29-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 GBCGDNIH2_RS03975 23463c6a640946225252343c3b88bce2 301 Gene3D G3DSA:3.30.1490.20 114 181 1.2E-9 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 GBCGDNIH2_RS03975 23463c6a640946225252343c3b88bce2 301 Gene3D G3DSA:3.30.470.20 182 285 1.7E-28 T 29-03-2018 GBCGDNIH2_RS03975 23463c6a640946225252343c3b88bce2 301 Gene3D G3DSA:3.40.50.20 11 113 6.9E-18 T 29-03-2018 GBCGDNIH2_RS03975 23463c6a640946225252343c3b88bce2 301 Pfam PF08443 RimK-like ATP-grasp domain 111 293 4.6E-21 T 29-03-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 GBCGDNIH2_RS03975 23463c6a640946225252343c3b88bce2 301 SUPERFAMILY SSF56059 111 294 1.77E-36 T 29-03-2018 GBCGDNIH2_RS10965 6bcf58769b7337526c2fba8e3ab1314c 651 Pfam PF13243 Squalene-hopene cyclase C-terminal domain 320 638 2.2E-140 T 29-03-2018 IPR032696 Squalene cyclase, C-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 GBCGDNIH2_RS10965 6bcf58769b7337526c2fba8e3ab1314c 651 Pfam PF13249 Squalene-hopene cyclase N-terminal domain 25 312 1.6E-115 T 29-03-2018 IPR032697 Squalene cyclase, N-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 GBCGDNIH2_RS10965 6bcf58769b7337526c2fba8e3ab1314c 651 SUPERFAMILY SSF48239 48 316 1.02E-73 T 29-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid GBCGDNIH2_RS10965 6bcf58769b7337526c2fba8e3ab1314c 651 TIGRFAM TIGR01507 hopene_cyclase: squalene-hopene cyclase 15 642 1.3E-241 T 29-03-2018 IPR006400 Squalene hopene cyclase GO:0016866|GO:0019746 KEGG: 00030+4.2.1.12|KEGG: 00909+4.2.1.129+5.4.99.17|MetaCyc: PWY-6098|MetaCyc: PWY-7072 GBCGDNIH2_RS10965 6bcf58769b7337526c2fba8e3ab1314c 651 Gene3D G3DSA:1.50.10.20 44 308 3.3E-64 T 29-03-2018 GBCGDNIH2_RS10965 6bcf58769b7337526c2fba8e3ab1314c 651 Gene3D G3DSA:1.50.10.20 309 648 2.4E-111 T 29-03-2018 GBCGDNIH2_RS10965 6bcf58769b7337526c2fba8e3ab1314c 651 TIGRFAM TIGR01787 squalene_cyclas: squalene/oxidosqualene cyclases 23 638 1.2E-187 T 29-03-2018 IPR018333 Squalene cyclase GO:0016866 Reactome: R-HSA-191273|Reactome: R-HSA-2426168 GBCGDNIH2_RS10965 6bcf58769b7337526c2fba8e3ab1314c 651 SUPERFAMILY SSF48239 251 271 1.96E-102 T 29-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid GBCGDNIH2_RS10965 6bcf58769b7337526c2fba8e3ab1314c 651 SUPERFAMILY SSF48239 316 638 1.96E-102 T 29-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid GBCGDNIH2_RS11670 091eaec7b6095fc96452a95679edd700 482 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 102 116 - T 29-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 GBCGDNIH2_RS11670 091eaec7b6095fc96452a95679edd700 482 Gene3D G3DSA:3.40.50.1100 106 204 1.2E-13 T 29-03-2018 GBCGDNIH2_RS11670 091eaec7b6095fc96452a95679edd700 482 Gene3D G3DSA:3.90.1380.10 1 86 6.4E-29 T 29-03-2018 IPR029144 Threonine synthase, N-terminal GBCGDNIH2_RS11670 091eaec7b6095fc96452a95679edd700 482 TIGRFAM TIGR00260 thrC: threonine synthase 70 430 1.1E-80 T 29-03-2018 IPR004450 Threonine synthase-like GBCGDNIH2_RS11670 091eaec7b6095fc96452a95679edd700 482 SUPERFAMILY SSF53686 1 465 1.0E-159 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme GBCGDNIH2_RS11670 091eaec7b6095fc96452a95679edd700 482 Pfam PF14821 Threonine synthase N terminus 2 80 2.6E-26 T 29-03-2018 IPR029144 Threonine synthase, N-terminal GBCGDNIH2_RS11670 091eaec7b6095fc96452a95679edd700 482 Gene3D G3DSA:3.40.50.1100 205 434 7.0E-79 T 29-03-2018 GBCGDNIH2_RS11670 091eaec7b6095fc96452a95679edd700 482 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 93 414 6.5E-22 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme GBCGDNIH2_RS11445 6bdb03b4fb0cd9b9ddfd4bfc51145792 279 Gene3D G3DSA:3.40.50.720 2 279 4.0E-42 T 29-03-2018 GBCGDNIH2_RS11445 6bdb03b4fb0cd9b9ddfd4bfc51145792 279 SUPERFAMILY SSF51735 25 276 4.26E-49 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS11445 6bdb03b4fb0cd9b9ddfd4bfc51145792 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 99 110 1.4E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS11445 6bdb03b4fb0cd9b9ddfd4bfc51145792 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 202 1.4E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS11445 6bdb03b4fb0cd9b9ddfd4bfc51145792 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 25 42 1.4E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS11445 6bdb03b4fb0cd9b9ddfd4bfc51145792 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 204 221 1.4E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS11445 6bdb03b4fb0cd9b9ddfd4bfc51145792 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 173 1.4E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS11445 6bdb03b4fb0cd9b9ddfd4bfc51145792 279 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 170 198 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 GBCGDNIH2_RS11445 6bdb03b4fb0cd9b9ddfd4bfc51145792 279 Pfam PF00106 short chain dehydrogenase 26 224 2.1E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS08520 ff056dc4e35cc666bbd81f78cac7a6ff 173 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 12 173 2.9E-65 T 29-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 GBCGDNIH2_RS08520 ff056dc4e35cc666bbd81f78cac7a6ff 173 SUPERFAMILY SSF54364 9 83 1.03E-28 T 29-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 GBCGDNIH2_RS08520 ff056dc4e35cc666bbd81f78cac7a6ff 173 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 5 173 28.596 T 29-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 GBCGDNIH2_RS08520 ff056dc4e35cc666bbd81f78cac7a6ff 173 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 88 172 2.7E-37 T 29-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 GBCGDNIH2_RS08520 ff056dc4e35cc666bbd81f78cac7a6ff 173 ProSitePatterns PS00938 Initiation factor 3 signature. 63 76 - T 29-03-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 GBCGDNIH2_RS08520 ff056dc4e35cc666bbd81f78cac7a6ff 173 Gene3D G3DSA:3.30.110.10 84 173 3.0E-34 T 29-03-2018 GBCGDNIH2_RS08520 ff056dc4e35cc666bbd81f78cac7a6ff 173 SUPERFAMILY SSF55200 87 172 5.76E-32 T 29-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 GBCGDNIH2_RS08520 ff056dc4e35cc666bbd81f78cac7a6ff 173 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 12 81 2.9E-30 T 29-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 GBCGDNIH2_RS08520 ff056dc4e35cc666bbd81f78cac7a6ff 173 Gene3D G3DSA:3.10.20.80 7 83 8.8E-32 T 29-03-2018 GBCGDNIH2_RS07845 69948666f2178afd31a66b8c1b5931ad 253 SUPERFAMILY SSF47413 32 93 2.6E-6 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GBCGDNIH2_RS07845 69948666f2178afd31a66b8c1b5931ad 253 SUPERFAMILY SSF51306 145 251 1.27E-13 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C GBCGDNIH2_RS07845 69948666f2178afd31a66b8c1b5931ad 253 Gene3D G3DSA:1.10.260.40 26 96 3.6E-7 T 29-03-2018 GBCGDNIH2_RS07845 69948666f2178afd31a66b8c1b5931ad 253 Gene3D G3DSA:2.10.109.10 123 253 3.7E-12 T 29-03-2018 GBCGDNIH2_RS09060 711ab9a954b0dc42dbf09260973c101b 822 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 684 700 - T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 GBCGDNIH2_RS09060 711ab9a954b0dc42dbf09260973c101b 822 Gene3D G3DSA:3.50.50.60 248 307 8.1E-6 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS09060 711ab9a954b0dc42dbf09260973c101b 822 Pfam PF04324 BFD-like [2Fe-2S] binding domain 488 538 1.7E-13 T 29-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain GBCGDNIH2_RS09060 711ab9a954b0dc42dbf09260973c101b 822 Pfam PF04324 BFD-like [2Fe-2S] binding domain 426 473 2.6E-11 T 29-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain GBCGDNIH2_RS09060 711ab9a954b0dc42dbf09260973c101b 822 Gene3D G3DSA:3.50.50.60 101 246 2.4E-31 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS09060 711ab9a954b0dc42dbf09260973c101b 822 SUPERFAMILY SSF51905 150 311 5.47E-27 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS09060 711ab9a954b0dc42dbf09260973c101b 822 SUPERFAMILY SSF56014 639 809 3.4E-49 T 29-03-2018 GBCGDNIH2_RS09060 711ab9a954b0dc42dbf09260973c101b 822 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 5 801 3.0E-267 T 29-03-2018 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 GBCGDNIH2_RS09060 711ab9a954b0dc42dbf09260973c101b 822 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 288 9.2E-50 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS09060 711ab9a954b0dc42dbf09260973c101b 822 Gene3D G3DSA:3.90.480.10 308 633 1.3E-19 T 29-03-2018 GBCGDNIH2_RS09060 711ab9a954b0dc42dbf09260973c101b 822 SUPERFAMILY SSF55124 525 646 9.16E-25 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 GBCGDNIH2_RS09060 711ab9a954b0dc42dbf09260973c101b 822 PIRSF PIRSF037149 1 820 0.0 T 29-03-2018 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 GBCGDNIH2_RS09060 711ab9a954b0dc42dbf09260973c101b 822 Gene3D G3DSA:3.30.413.10 636 815 2.9E-37 T 29-03-2018 GBCGDNIH2_RS09060 711ab9a954b0dc42dbf09260973c101b 822 PRINTS PR00397 Sirohaem Fe-binding site signature 684 702 5.1E-6 T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 GBCGDNIH2_RS09060 711ab9a954b0dc42dbf09260973c101b 822 PRINTS PR00397 Sirohaem Fe-binding site signature 641 659 5.1E-6 T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 GBCGDNIH2_RS09060 711ab9a954b0dc42dbf09260973c101b 822 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 564 627 5.6E-12 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 GBCGDNIH2_RS09060 711ab9a954b0dc42dbf09260973c101b 822 SUPERFAMILY SSF51905 3 195 2.59E-40 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS09060 711ab9a954b0dc42dbf09260973c101b 822 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 638 774 3.0E-26 T 29-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 GBCGDNIH2_RS09060 711ab9a954b0dc42dbf09260973c101b 822 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 101 119 1.8E-13 T 29-03-2018 GBCGDNIH2_RS09060 711ab9a954b0dc42dbf09260973c101b 822 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 237 253 1.8E-13 T 29-03-2018 GBCGDNIH2_RS09060 711ab9a954b0dc42dbf09260973c101b 822 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 150 168 1.8E-13 T 29-03-2018 GBCGDNIH2_RS09060 711ab9a954b0dc42dbf09260973c101b 822 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 262 284 1.8E-13 T 29-03-2018 GBCGDNIH2_RS09060 711ab9a954b0dc42dbf09260973c101b 822 Gene3D G3DSA:3.50.50.60 11 100 6.6E-10 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS10400 cecb82215dc911f1f93355ddc5f64b19 280 Pfam PF00459 Inositol monophosphatase family 11 262 5.0E-44 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 GBCGDNIH2_RS10400 cecb82215dc911f1f93355ddc5f64b19 280 Gene3D G3DSA:3.30.540.10 7 140 1.3E-39 T 29-03-2018 GBCGDNIH2_RS10400 cecb82215dc911f1f93355ddc5f64b19 280 SUPERFAMILY SSF56655 11 272 2.09E-64 T 29-03-2018 GBCGDNIH2_RS10400 cecb82215dc911f1f93355ddc5f64b19 280 Gene3D G3DSA:3.40.190.80 159 280 3.4E-19 T 29-03-2018 GBCGDNIH2_RS10400 cecb82215dc911f1f93355ddc5f64b19 280 PRINTS PR00377 Inositol monophosphatase superfamily signature 67 83 4.8E-16 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 GBCGDNIH2_RS10400 cecb82215dc911f1f93355ddc5f64b19 280 PRINTS PR00377 Inositol monophosphatase superfamily signature 219 243 4.8E-16 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 GBCGDNIH2_RS10400 cecb82215dc911f1f93355ddc5f64b19 280 PRINTS PR00377 Inositol monophosphatase superfamily signature 45 65 4.8E-16 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 GBCGDNIH2_RS10400 cecb82215dc911f1f93355ddc5f64b19 280 PRINTS PR00377 Inositol monophosphatase superfamily signature 87 103 4.8E-16 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 GBCGDNIH2_RS10400 cecb82215dc911f1f93355ddc5f64b19 280 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 87 100 - T 29-03-2018 IPR020583 Inositol monophosphatase, metal-binding site GBCGDNIH2_RS03095 caccb6e2571c6dfae0df788e019020b0 415 Pfam PF13393 Histidyl-tRNA synthetase 9 311 1.7E-39 T 29-03-2018 GBCGDNIH2_RS03095 caccb6e2571c6dfae0df788e019020b0 415 Gene3D G3DSA:3.30.930.10 1 319 2.7E-70 T 29-03-2018 GBCGDNIH2_RS03095 caccb6e2571c6dfae0df788e019020b0 415 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 5 401 3.2E-141 T 29-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 GBCGDNIH2_RS03095 caccb6e2571c6dfae0df788e019020b0 415 SUPERFAMILY SSF55681 5 317 1.55E-92 T 29-03-2018 GBCGDNIH2_RS03095 caccb6e2571c6dfae0df788e019020b0 415 PIRSF PIRSF001549 1 411 1.7E-110 T 29-03-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 GBCGDNIH2_RS03095 caccb6e2571c6dfae0df788e019020b0 415 Pfam PF03129 Anticodon binding domain 325 411 6.1E-12 T 29-03-2018 IPR004154 Anticodon-binding GBCGDNIH2_RS03095 caccb6e2571c6dfae0df788e019020b0 415 SUPERFAMILY SSF52954 321 410 1.34E-19 T 29-03-2018 IPR004154 Anticodon-binding GBCGDNIH2_RS03095 caccb6e2571c6dfae0df788e019020b0 415 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 2 411 30.76 T 29-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 GBCGDNIH2_RS03095 caccb6e2571c6dfae0df788e019020b0 415 Gene3D G3DSA:3.40.50.800 320 412 5.7E-19 T 29-03-2018 IPR004154 Anticodon-binding GBCGDNIH2_RS11510 b3fc4c6957f0795cf6b6ee8064f6d46a 438 Gene3D G3DSA:1.20.5.100 198 220 4.6E-15 T 29-03-2018 GBCGDNIH2_RS11510 b3fc4c6957f0795cf6b6ee8064f6d46a 438 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 197 289 2.5E-38 T 29-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 GBCGDNIH2_RS11510 b3fc4c6957f0795cf6b6ee8064f6d46a 438 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 2 411 1.3E-132 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 GBCGDNIH2_RS11510 b3fc4c6957f0795cf6b6ee8064f6d46a 438 Gene3D G3DSA:3.40.50.720 1 194 3.7E-59 T 29-03-2018 GBCGDNIH2_RS11510 b3fc4c6957f0795cf6b6ee8064f6d46a 438 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 314 415 8.0E-29 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 GBCGDNIH2_RS11510 b3fc4c6957f0795cf6b6ee8064f6d46a 438 SMART SM00984 313 415 4.3E-46 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 GBCGDNIH2_RS11510 b3fc4c6957f0795cf6b6ee8064f6d46a 438 PIRSF PIRSF000124 1 430 1.3E-136 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 GBCGDNIH2_RS11510 b3fc4c6957f0795cf6b6ee8064f6d46a 438 PIRSF PIRSF500134 1 433 9.5E-172 T 29-03-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 GBCGDNIH2_RS11510 b3fc4c6957f0795cf6b6ee8064f6d46a 438 Gene3D G3DSA:3.40.50.720 221 427 6.2E-77 T 29-03-2018 GBCGDNIH2_RS11510 b3fc4c6957f0795cf6b6ee8064f6d46a 438 SUPERFAMILY SSF48179 197 294 2.21E-34 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 GBCGDNIH2_RS11510 b3fc4c6957f0795cf6b6ee8064f6d46a 438 SUPERFAMILY SSF51735 2 184 2.1E-49 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS11510 b3fc4c6957f0795cf6b6ee8064f6d46a 438 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2 179 6.6E-56 T 29-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 GBCGDNIH2_RS11510 b3fc4c6957f0795cf6b6ee8064f6d46a 438 SUPERFAMILY SSF52413 299 425 2.75E-37 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 GBCGDNIH2_RS00560 a08dff64724391fce1c4d7e9369c421b 161 Gene3D G3DSA:1.20.1260.10 1 149 5.0E-36 T 29-03-2018 IPR012347 Ferritin-related GBCGDNIH2_RS00560 a08dff64724391fce1c4d7e9369c421b 161 PIRSF PIRSF002560 1 157 2.7E-64 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 GBCGDNIH2_RS00560 a08dff64724391fce1c4d7e9369c421b 161 TIGRFAM TIGR00754 bfr: bacterioferritin 1 151 2.4E-62 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 GBCGDNIH2_RS00560 a08dff64724391fce1c4d7e9369c421b 161 Pfam PF00210 Ferritin-like domain 8 144 6.0E-36 T 29-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 GBCGDNIH2_RS00560 a08dff64724391fce1c4d7e9369c421b 161 SUPERFAMILY SSF47240 1 154 1.45E-48 T 29-03-2018 IPR009078 Ferritin-like superfamily GBCGDNIH2_RS00560 a08dff64724391fce1c4d7e9369c421b 161 PRINTS PR00601 Bacterioferritin signature 44 64 3.8E-58 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 GBCGDNIH2_RS00560 a08dff64724391fce1c4d7e9369c421b 161 PRINTS PR00601 Bacterioferritin signature 86 106 3.8E-58 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 GBCGDNIH2_RS00560 a08dff64724391fce1c4d7e9369c421b 161 PRINTS PR00601 Bacterioferritin signature 128 149 3.8E-58 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 GBCGDNIH2_RS00560 a08dff64724391fce1c4d7e9369c421b 161 PRINTS PR00601 Bacterioferritin signature 65 85 3.8E-58 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 GBCGDNIH2_RS00560 a08dff64724391fce1c4d7e9369c421b 161 PRINTS PR00601 Bacterioferritin signature 3 22 3.8E-58 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 GBCGDNIH2_RS00560 a08dff64724391fce1c4d7e9369c421b 161 PRINTS PR00601 Bacterioferritin signature 23 43 3.8E-58 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 GBCGDNIH2_RS00560 a08dff64724391fce1c4d7e9369c421b 161 PRINTS PR00601 Bacterioferritin signature 107 127 3.8E-58 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 GBCGDNIH2_RS00075 f5032bd25977a5f12ad5fd57e300d8c1 182 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 84 161 8.7E-30 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 GBCGDNIH2_RS00075 f5032bd25977a5f12ad5fd57e300d8c1 182 SUPERFAMILY SSF53155 18 86 3.53E-13 T 29-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 GBCGDNIH2_RS00075 f5032bd25977a5f12ad5fd57e300d8c1 182 Gene3D G3DSA:3.30.160.70 19 76 6.5E-14 T 29-03-2018 GBCGDNIH2_RS00075 f5032bd25977a5f12ad5fd57e300d8c1 182 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 20 162 37.998 T 29-03-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 GBCGDNIH2_RS00075 f5032bd25977a5f12ad5fd57e300d8c1 182 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 82 161 1.3E-29 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 GBCGDNIH2_RS00075 f5032bd25977a5f12ad5fd57e300d8c1 182 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 130 136 - T 29-03-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 GBCGDNIH2_RS00075 f5032bd25977a5f12ad5fd57e300d8c1 182 Gene3D G3DSA:1.10.10.10 77 163 2.5E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS00075 f5032bd25977a5f12ad5fd57e300d8c1 182 SUPERFAMILY SSF46767 81 162 1.83E-27 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 GBCGDNIH2_RS09665 ff6dbde0e14674a530d9d1a169f75929 308 PIRSF PIRSF002936 7 308 1.8E-140 T 29-03-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 GBCGDNIH2_RS09665 ff6dbde0e14674a530d9d1a169f75929 308 Gene3D G3DSA:3.40.50.620 1 306 1.1E-43 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GBCGDNIH2_RS09665 ff6dbde0e14674a530d9d1a169f75929 308 Hamap MF_00064 Sulfate adenylyltransferase subunit 2 [cysD]. 10 308 53.391 T 29-03-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 GBCGDNIH2_RS09665 ff6dbde0e14674a530d9d1a169f75929 308 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 15 308 1.5E-147 T 29-03-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 GBCGDNIH2_RS09665 ff6dbde0e14674a530d9d1a169f75929 308 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 36 263 1.4E-61 T 29-03-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 GBCGDNIH2_RS09665 ff6dbde0e14674a530d9d1a169f75929 308 SUPERFAMILY SSF52402 14 216 6.98E-71 T 29-03-2018 GBCGDNIH2_RS12540 71b91d7a89f62dec82ed3c50cd4d14fd 460 PIRSF PIRSF000337 2 448 8.0E-140 T 29-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 GBCGDNIH2_RS12540 71b91d7a89f62dec82ed3c50cd4d14fd 460 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 7 434 3.8E-173 T 29-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 GBCGDNIH2_RS12540 71b91d7a89f62dec82ed3c50cd4d14fd 460 Gene3D G3DSA:3.20.20.30 1 458 1.1E-113 T 29-03-2018 GBCGDNIH2_RS12540 71b91d7a89f62dec82ed3c50cd4d14fd 460 SUPERFAMILY SSF51679 1 438 2.36E-128 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 GBCGDNIH2_RS12540 71b91d7a89f62dec82ed3c50cd4d14fd 460 Pfam PF00296 Luciferase-like monooxygenase 23 392 1.3E-52 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 GBCGDNIH2_RS07785 76a8e2aed4744685be52ec1eefba58fb 298 SUPERFAMILY SSF49493 193 266 1.16E-16 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 GBCGDNIH2_RS07785 76a8e2aed4744685be52ec1eefba58fb 298 SUPERFAMILY SSF49493 114 198 3.79E-18 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 GBCGDNIH2_RS07785 76a8e2aed4744685be52ec1eefba58fb 298 ProSitePatterns PS00636 Nt-dnaJ domain signature. 45 64 - T 29-03-2018 IPR018253 DnaJ domain, conserved site GBCGDNIH2_RS07785 76a8e2aed4744685be52ec1eefba58fb 298 PRINTS PR00625 DnaJ domain signature 60 79 1.9E-20 T 29-03-2018 IPR001623 DnaJ domain GBCGDNIH2_RS07785 76a8e2aed4744685be52ec1eefba58fb 298 PRINTS PR00625 DnaJ domain signature 23 38 1.9E-20 T 29-03-2018 IPR001623 DnaJ domain GBCGDNIH2_RS07785 76a8e2aed4744685be52ec1eefba58fb 298 PRINTS PR00625 DnaJ domain signature 40 60 1.9E-20 T 29-03-2018 IPR001623 DnaJ domain GBCGDNIH2_RS07785 76a8e2aed4744685be52ec1eefba58fb 298 PRINTS PR00625 DnaJ domain signature 5 23 1.9E-20 T 29-03-2018 IPR001623 DnaJ domain GBCGDNIH2_RS07785 76a8e2aed4744685be52ec1eefba58fb 298 SUPERFAMILY SSF46565 3 108 4.32E-27 T 29-03-2018 IPR001623 DnaJ domain GBCGDNIH2_RS07785 76a8e2aed4744685be52ec1eefba58fb 298 SMART SM00271 2 60 5.7E-25 T 29-03-2018 IPR001623 DnaJ domain GBCGDNIH2_RS07785 76a8e2aed4744685be52ec1eefba58fb 298 Gene3D G3DSA:1.10.287.110 1 116 2.8E-29 T 29-03-2018 IPR001623 DnaJ domain GBCGDNIH2_RS07785 76a8e2aed4744685be52ec1eefba58fb 298 Gene3D G3DSA:2.60.260.20 189 296 2.5E-19 T 29-03-2018 GBCGDNIH2_RS07785 76a8e2aed4744685be52ec1eefba58fb 298 Pfam PF01556 DnaJ C terminal domain 122 264 4.5E-30 T 29-03-2018 IPR002939 Chaperone DnaJ, C-terminal GBCGDNIH2_RS07785 76a8e2aed4744685be52ec1eefba58fb 298 Pfam PF00226 DnaJ domain 3 65 1.6E-23 T 29-03-2018 IPR001623 DnaJ domain GBCGDNIH2_RS07785 76a8e2aed4744685be52ec1eefba58fb 298 Gene3D G3DSA:2.60.260.20 117 188 1.3E-16 T 29-03-2018 GBCGDNIH2_RS01900 2e0304b143895cb7f6ec8beef9a7bb89 611 Pfam PF01432 Peptidase family M3 354 596 5.7E-31 T 29-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 GBCGDNIH2_RS01900 2e0304b143895cb7f6ec8beef9a7bb89 611 Pfam PF08439 Oligopeptidase F 133 200 1.0E-17 T 29-03-2018 IPR013647 Oligopeptidase F, N-terminal domain GBCGDNIH2_RS01900 2e0304b143895cb7f6ec8beef9a7bb89 611 TIGRFAM TIGR02290 M3_fam_3: oligoendopeptidase, pepF/M3 family 30 609 6.7E-184 T 29-03-2018 IPR011977 Peptidase M3B, oligoendopeptidase-related clade 3 GBCGDNIH2_RS01900 2e0304b143895cb7f6ec8beef9a7bb89 611 Gene3D G3DSA:1.10.1370.10 71 591 3.9E-28 T 29-03-2018 GBCGDNIH2_RS01900 2e0304b143895cb7f6ec8beef9a7bb89 611 SUPERFAMILY SSF55486 28 596 9.9E-119 T 29-03-2018 GBCGDNIH2_RS02865 afcc36b98e6d4c24205d8343a77c5266 225 SUPERFAMILY SSF54821 107 205 2.49E-41 T 29-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02865 afcc36b98e6d4c24205d8343a77c5266 225 SMART SM00322 59 124 1.9E-4 T 29-03-2018 IPR004087 K Homology domain GO:0003676 GBCGDNIH2_RS02865 afcc36b98e6d4c24205d8343a77c5266 225 Pfam PF07650 KH domain 38 109 2.7E-17 T 29-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02865 afcc36b98e6d4c24205d8343a77c5266 225 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 205 38.308 T 29-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 GBCGDNIH2_RS02865 afcc36b98e6d4c24205d8343a77c5266 225 SUPERFAMILY SSF54814 2 105 4.19E-35 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 GBCGDNIH2_RS02865 afcc36b98e6d4c24205d8343a77c5266 225 ProSitePatterns PS00548 Ribosomal protein S3 signature. 162 196 - T 29-03-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02865 afcc36b98e6d4c24205d8343a77c5266 225 Pfam PF00189 Ribosomal protein S3, C-terminal domain 119 201 1.4E-40 T 29-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02865 afcc36b98e6d4c24205d8343a77c5266 225 Gene3D G3DSA:3.30.1140.32 107 207 1.7E-39 T 29-03-2018 GBCGDNIH2_RS02865 afcc36b98e6d4c24205d8343a77c5266 225 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 208 3.1E-91 T 29-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 GBCGDNIH2_RS02865 afcc36b98e6d4c24205d8343a77c5266 225 Gene3D G3DSA:3.30.300.20 17 106 3.9E-24 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta GBCGDNIH2_RS11855 dfa087b614ad0bcd639b021809839435 157 Gene3D G3DSA:1.10.287.180 3 76 1.3E-32 T 29-03-2018 GBCGDNIH2_RS11855 dfa087b614ad0bcd639b021809839435 157 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 81 155 3.0E-27 T 29-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 GBCGDNIH2_RS11855 dfa087b614ad0bcd639b021809839435 157 SUPERFAMILY SSF54534 81 156 4.32E-22 T 29-03-2018 GBCGDNIH2_RS11855 dfa087b614ad0bcd639b021809839435 157 Pfam PF03449 Transcription elongation factor, N-terminal 5 74 3.4E-31 T 29-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 GBCGDNIH2_RS11855 dfa087b614ad0bcd639b021809839435 157 PIRSF PIRSF006092 1 156 2.7E-52 T 29-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 GBCGDNIH2_RS11855 dfa087b614ad0bcd639b021809839435 157 SUPERFAMILY SSF46557 3 78 4.32E-28 T 29-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 GBCGDNIH2_RS11855 dfa087b614ad0bcd639b021809839435 157 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 5 154 1.9E-60 T 29-03-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 GBCGDNIH2_RS11855 dfa087b614ad0bcd639b021809839435 157 Hamap MF_00105 Transcription elongation factor GreA [greA]. 2 155 32.281 T 29-03-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 GBCGDNIH2_RS11855 dfa087b614ad0bcd639b021809839435 157 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 17 48 - T 29-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 GBCGDNIH2_RS11855 dfa087b614ad0bcd639b021809839435 157 Gene3D G3DSA:3.10.50.30 77 157 1.7E-26 T 29-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 GBCGDNIH2_RS11855 dfa087b614ad0bcd639b021809839435 157 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 120 136 - T 29-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 GBCGDNIH2_RS08495 8a4381c14a9e3e74b116fddd32b23325 484 Hamap MF_00804 NAD/NADP-dependent betaine aldehyde dehydrogenase [betB]. 2 484 56.196 T 29-03-2018 IPR011264 Betaine aldehyde dehydrogenase GO:0008802|GO:0019285|GO:0046872 KEGG: 00260+1.2.1.8|MetaCyc: PWY-3722|MetaCyc: PWY-7494 GBCGDNIH2_RS08495 8a4381c14a9e3e74b116fddd32b23325 484 Gene3D G3DSA:3.40.605.10 1 263 4.6E-98 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 GBCGDNIH2_RS08495 8a4381c14a9e3e74b116fddd32b23325 484 Pfam PF00171 Aldehyde dehydrogenase family 16 473 1.7E-169 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 GBCGDNIH2_RS08495 8a4381c14a9e3e74b116fddd32b23325 484 SUPERFAMILY SSF53720 3 478 6.41E-164 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 GBCGDNIH2_RS08495 8a4381c14a9e3e74b116fddd32b23325 484 TIGRFAM TIGR01804 BADH: betaine-aldehyde dehydrogenase 6 471 4.4E-211 T 29-03-2018 IPR011264 Betaine aldehyde dehydrogenase GO:0008802|GO:0019285|GO:0046872 KEGG: 00260+1.2.1.8|MetaCyc: PWY-3722|MetaCyc: PWY-7494 GBCGDNIH2_RS08495 8a4381c14a9e3e74b116fddd32b23325 484 Gene3D G3DSA:3.40.309.10 264 459 1.9E-69 T 29-03-2018 GBCGDNIH2_RS08495 8a4381c14a9e3e74b116fddd32b23325 484 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 273 284 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 GBCGDNIH2_RS08495 8a4381c14a9e3e74b116fddd32b23325 484 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 245 252 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 GBCGDNIH2_RS02125 2918a254351f5442994f76b166683f30 868 Gene3D G3DSA:3.30.1340.10 175 259 4.8E-23 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like GBCGDNIH2_RS02125 2918a254351f5442994f76b166683f30 868 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 535 830 9.8E-100 T 29-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 GBCGDNIH2_RS02125 2918a254351f5442994f76b166683f30 868 SUPERFAMILY SSF52009 407 525 7.85E-30 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 GBCGDNIH2_RS02125 2918a254351f5442994f76b166683f30 868 Pfam PF00381 PTS HPr component phosphorylation site 178 254 3.2E-21 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like GBCGDNIH2_RS02125 2918a254351f5442994f76b166683f30 868 SUPERFAMILY SSF51621 539 839 3.93E-97 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 GBCGDNIH2_RS02125 2918a254351f5442994f76b166683f30 868 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 23 154 1.8E-28 T 29-03-2018 IPR002178 PTS EIIA type-2 domain GBCGDNIH2_RS02125 2918a254351f5442994f76b166683f30 868 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 790 802 1.3E-21 T 29-03-2018 GBCGDNIH2_RS02125 2918a254351f5442994f76b166683f30 868 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 754 769 1.3E-21 T 29-03-2018 GBCGDNIH2_RS02125 2918a254351f5442994f76b166683f30 868 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 576 595 1.3E-21 T 29-03-2018 GBCGDNIH2_RS02125 2918a254351f5442994f76b166683f30 868 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 737 752 1.3E-21 T 29-03-2018 GBCGDNIH2_RS02125 2918a254351f5442994f76b166683f30 868 Pfam PF00391 PEP-utilising enzyme, mobile domain 438 508 7.5E-21 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 GBCGDNIH2_RS02125 2918a254351f5442994f76b166683f30 868 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 178 254 6.8E-18 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like GBCGDNIH2_RS02125 2918a254351f5442994f76b166683f30 868 Gene3D G3DSA:3.20.20.60 533 863 6.4E-91 T 29-03-2018 GBCGDNIH2_RS02125 2918a254351f5442994f76b166683f30 868 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 287 854 3.0E-144 T 29-03-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 GBCGDNIH2_RS02125 2918a254351f5442994f76b166683f30 868 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 737 755 - T 29-03-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 GBCGDNIH2_RS02125 2918a254351f5442994f76b166683f30 868 SUPERFAMILY SSF55594 177 255 2.49E-20 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like GBCGDNIH2_RS02125 2918a254351f5442994f76b166683f30 868 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 467 478 - T 29-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 GBCGDNIH2_RS02125 2918a254351f5442994f76b166683f30 868 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 186 193 - T 29-03-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site GBCGDNIH2_RS02125 2918a254351f5442994f76b166683f30 868 Gene3D G3DSA:1.10.274.10 310 426 7.7E-26 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 GBCGDNIH2_RS02125 2918a254351f5442994f76b166683f30 868 SUPERFAMILY SSF55804 21 154 3.79E-32 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 GBCGDNIH2_RS02125 2918a254351f5442994f76b166683f30 868 PRINTS PR00107 Phosphocarrier protein signature 226 243 5.9E-13 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like GBCGDNIH2_RS02125 2918a254351f5442994f76b166683f30 868 PRINTS PR00107 Phosphocarrier protein signature 211 226 5.9E-13 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like GBCGDNIH2_RS02125 2918a254351f5442994f76b166683f30 868 PRINTS PR00107 Phosphocarrier protein signature 186 202 5.9E-13 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like GBCGDNIH2_RS02125 2918a254351f5442994f76b166683f30 868 Gene3D G3DSA:3.50.30.10 430 526 1.8E-23 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 GBCGDNIH2_RS02125 2918a254351f5442994f76b166683f30 868 Pfam PF05524 PEP-utilising enzyme, N-terminal 288 407 2.1E-22 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 GBCGDNIH2_RS02125 2918a254351f5442994f76b166683f30 868 Gene3D G3DSA:3.40.930.10 13 157 2.7E-26 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 GBCGDNIH2_RS02125 2918a254351f5442994f76b166683f30 868 SUPERFAMILY SSF47831 315 422 3.4E-25 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 GBCGDNIH2_RS00480 cf8fbbc94f956336d4d837119b6c381c 285 SUPERFAMILY SSF51735 41 283 5.52E-82 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS00480 cf8fbbc94f956336d4d837119b6c381c 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 246 266 3.6E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS00480 cf8fbbc94f956336d4d837119b6c381c 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 44 61 3.6E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS00480 cf8fbbc94f956336d4d837119b6c381c 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 229 3.6E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS00480 cf8fbbc94f956336d4d837119b6c381c 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 191 210 3.6E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS00480 cf8fbbc94f956336d4d837119b6c381c 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 181 3.6E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS00480 cf8fbbc94f956336d4d837119b6c381c 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 130 3.6E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS00480 cf8fbbc94f956336d4d837119b6c381c 285 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 52 281 3.2E-62 T 29-03-2018 GBCGDNIH2_RS00480 cf8fbbc94f956336d4d837119b6c381c 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 191 210 3.6E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS00480 cf8fbbc94f956336d4d837119b6c381c 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 119 130 3.6E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS00480 cf8fbbc94f956336d4d837119b6c381c 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 171 179 3.6E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS00480 cf8fbbc94f956336d4d837119b6c381c 285 Gene3D G3DSA:3.40.50.720 2 285 2.3E-76 T 29-03-2018 GBCGDNIH2_RS00480 cf8fbbc94f956336d4d837119b6c381c 285 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 178 206 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 GBCGDNIH2_RS00460 ec26025c49fa3eea88cfdf08104e401f 229 Gene3D G3DSA:3.40.50.880 1 228 1.9E-47 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like GBCGDNIH2_RS00460 ec26025c49fa3eea88cfdf08104e401f 229 SUPERFAMILY SSF52317 1 227 1.26E-65 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like GBCGDNIH2_RS00460 ec26025c49fa3eea88cfdf08104e401f 229 Pfam PF01965 DJ-1/PfpI family 29 219 2.4E-10 T 29-03-2018 IPR002818 DJ-1/PfpI GBCGDNIH2_RS02950 86f3250b81a1d8bfae2c04a48375ccc2 131 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 12 128 8.8E-57 T 29-03-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS02950 86f3250b81a1d8bfae2c04a48375ccc2 131 PIRSF PIRSF002131 1 131 5.5E-52 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 GBCGDNIH2_RS02950 86f3250b81a1d8bfae2c04a48375ccc2 131 Gene3D G3DSA:3.30.420.80 7 131 1.0E-44 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 GBCGDNIH2_RS02950 86f3250b81a1d8bfae2c04a48375ccc2 131 ProSitePatterns PS00054 Ribosomal protein S11 signature. 99 121 - T 29-03-2018 IPR018102 Ribosomal S11, conserved site GBCGDNIH2_RS02950 86f3250b81a1d8bfae2c04a48375ccc2 131 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 3 131 32.959 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 GBCGDNIH2_RS02950 86f3250b81a1d8bfae2c04a48375ccc2 131 SUPERFAMILY SSF53137 16 131 1.05E-46 T 29-03-2018 GBCGDNIH2_RS02950 86f3250b81a1d8bfae2c04a48375ccc2 131 Pfam PF00411 Ribosomal protein S11 21 130 1.2E-47 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 GBCGDNIH2_RS00025 d431e8fafef2117cb78d99305791089b 875 Pfam PF09334 tRNA synthetases class I (M) 52 186 7.8E-17 T 29-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 GBCGDNIH2_RS00025 d431e8fafef2117cb78d99305791089b 875 Gene3D G3DSA:1.10.730.10 660 810 3.6E-30 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 GBCGDNIH2_RS00025 d431e8fafef2117cb78d99305791089b 875 PRINTS PR00985 Leucyl-tRNA synthetase signature 142 159 1.2E-44 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 GBCGDNIH2_RS00025 d431e8fafef2117cb78d99305791089b 875 PRINTS PR00985 Leucyl-tRNA synthetase signature 200 213 1.2E-44 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 GBCGDNIH2_RS00025 d431e8fafef2117cb78d99305791089b 875 PRINTS PR00985 Leucyl-tRNA synthetase signature 578 588 1.2E-44 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 GBCGDNIH2_RS00025 d431e8fafef2117cb78d99305791089b 875 PRINTS PR00985 Leucyl-tRNA synthetase signature 168 184 1.2E-44 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 GBCGDNIH2_RS00025 d431e8fafef2117cb78d99305791089b 875 PRINTS PR00985 Leucyl-tRNA synthetase signature 230 249 1.2E-44 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 GBCGDNIH2_RS00025 d431e8fafef2117cb78d99305791089b 875 PRINTS PR00985 Leucyl-tRNA synthetase signature 507 525 1.2E-44 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 GBCGDNIH2_RS00025 d431e8fafef2117cb78d99305791089b 875 PRINTS PR00985 Leucyl-tRNA synthetase signature 545 567 1.2E-44 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 GBCGDNIH2_RS00025 d431e8fafef2117cb78d99305791089b 875 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 237 423 6.8E-66 T 29-03-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 GBCGDNIH2_RS00025 d431e8fafef2117cb78d99305791089b 875 SUPERFAMILY SSF47323 677 873 3.55E-30 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 GBCGDNIH2_RS00025 d431e8fafef2117cb78d99305791089b 875 Gene3D G3DSA:3.40.50.620 424 659 3.1E-65 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GBCGDNIH2_RS00025 d431e8fafef2117cb78d99305791089b 875 Gene3D G3DSA:3.40.50.620 11 240 6.3E-71 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GBCGDNIH2_RS00025 d431e8fafef2117cb78d99305791089b 875 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 18 873 3.4E-300 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 GBCGDNIH2_RS00025 d431e8fafef2117cb78d99305791089b 875 Pfam PF08264 Anticodon-binding domain of tRNA 715 838 2.4E-17 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 GBCGDNIH2_RS00025 d431e8fafef2117cb78d99305791089b 875 SUPERFAMILY SSF52374 18 241 7.72E-140 T 29-03-2018 GBCGDNIH2_RS00025 d431e8fafef2117cb78d99305791089b 875 SUPERFAMILY SSF52374 436 679 7.72E-140 T 29-03-2018 GBCGDNIH2_RS00025 d431e8fafef2117cb78d99305791089b 875 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 17 873 21.809 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 GBCGDNIH2_RS00025 d431e8fafef2117cb78d99305791089b 875 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 57 68 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 GBCGDNIH2_RS00025 d431e8fafef2117cb78d99305791089b 875 SUPERFAMILY SSF50677 241 435 3.87E-49 T 29-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 GBCGDNIH2_RS00025 d431e8fafef2117cb78d99305791089b 875 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 627 670 7.8E-8 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 GBCGDNIH2_RS00025 d431e8fafef2117cb78d99305791089b 875 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 437 593 5.0E-7 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 GBCGDNIH2_RS00025 d431e8fafef2117cb78d99305791089b 875 Gene3D G3DSA:3.90.740.10 241 423 3.1E-49 T 29-03-2018 GBCGDNIH2_RS09840 ddb20c4d2087cc3ef684845098e70f1b 358 Gene3D G3DSA:3.20.20.70 4 357 5.1E-82 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS09840 ddb20c4d2087cc3ef684845098e70f1b 358 SUPERFAMILY SSF51395 13 353 1.04E-93 T 29-03-2018 GBCGDNIH2_RS09840 ddb20c4d2087cc3ef684845098e70f1b 358 Pfam PF01180 Dihydroorotate dehydrogenase 46 337 1.9E-78 T 29-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 GBCGDNIH2_RS09840 ddb20c4d2087cc3ef684845098e70f1b 358 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 81 100 - T 29-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 GBCGDNIH2_RS09840 ddb20c4d2087cc3ef684845098e70f1b 358 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 14 352 4.4E-101 T 29-03-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 GBCGDNIH2_RS01845 a227ea169f0cddf2156ac6a3515501a1 495 SUPERFAMILY SSF53448 27 306 2.35E-68 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS01845 a227ea169f0cddf2156ac6a3515501a1 495 SUPERFAMILY SSF51182 211 494 3.78E-79 T 29-03-2018 IPR011051 RmlC-like cupin domain GBCGDNIH2_RS01845 a227ea169f0cddf2156ac6a3515501a1 495 Pfam PF00483 Nucleotidyl transferase 29 310 2.2E-60 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 GBCGDNIH2_RS01845 a227ea169f0cddf2156ac6a3515501a1 495 TIGRFAM TIGR01479 GMP_PMI: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 27 494 1.7E-206 T 29-03-2018 IPR006375 Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase GO:0000271|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 GBCGDNIH2_RS01845 a227ea169f0cddf2156ac6a3515501a1 495 Gene3D G3DSA:3.90.550.10 26 362 4.9E-89 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS01845 a227ea169f0cddf2156ac6a3515501a1 495 Gene3D G3DSA:2.60.120.10 363 473 1.3E-27 T 29-03-2018 IPR014710 RmlC-like jelly roll fold GBCGDNIH2_RS01845 a227ea169f0cddf2156ac6a3515501a1 495 Pfam PF01050 Mannose-6-phosphate isomerase 340 490 1.3E-67 T 29-03-2018 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 GBCGDNIH2_RS01635 0ce365a4fe069f01829fe0dea448d7f7 646 PRINTS PR00775 90kDa heat shock protein signature 21 41 9.9E-56 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal GBCGDNIH2_RS01635 0ce365a4fe069f01829fe0dea448d7f7 646 PRINTS PR00775 90kDa heat shock protein signature 42 64 9.9E-56 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal GBCGDNIH2_RS01635 0ce365a4fe069f01829fe0dea448d7f7 646 PRINTS PR00775 90kDa heat shock protein signature 141 163 9.9E-56 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal GBCGDNIH2_RS01635 0ce365a4fe069f01829fe0dea448d7f7 646 PRINTS PR00775 90kDa heat shock protein signature 209 227 9.9E-56 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal GBCGDNIH2_RS01635 0ce365a4fe069f01829fe0dea448d7f7 646 PRINTS PR00775 90kDa heat shock protein signature 191 208 9.9E-56 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal GBCGDNIH2_RS01635 0ce365a4fe069f01829fe0dea448d7f7 646 PRINTS PR00775 90kDa heat shock protein signature 109 126 9.9E-56 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal GBCGDNIH2_RS01635 0ce365a4fe069f01829fe0dea448d7f7 646 PRINTS PR00775 90kDa heat shock protein signature 91 108 9.9E-56 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal GBCGDNIH2_RS01635 0ce365a4fe069f01829fe0dea448d7f7 646 SMART SM00387 43 203 4.4E-5 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS01635 0ce365a4fe069f01829fe0dea448d7f7 646 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 45 174 7.3E-11 T 29-03-2018 GBCGDNIH2_RS01635 0ce365a4fe069f01829fe0dea448d7f7 646 SUPERFAMILY SSF54211 243 496 1.44E-80 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold GBCGDNIH2_RS01635 0ce365a4fe069f01829fe0dea448d7f7 646 SUPERFAMILY SSF110942 515 631 3.53E-24 T 29-03-2018 GBCGDNIH2_RS01635 0ce365a4fe069f01829fe0dea448d7f7 646 Pfam PF00183 Hsp90 protein 235 641 2.3E-97 T 29-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 GBCGDNIH2_RS01635 0ce365a4fe069f01829fe0dea448d7f7 646 Hamap MF_00505 Chaperone protein HtpG [htpG]. 18 632 27.838 T 29-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 GBCGDNIH2_RS01635 0ce365a4fe069f01829fe0dea448d7f7 646 PIRSF PIRSF002583 2 645 2.1E-185 T 29-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 GBCGDNIH2_RS01635 0ce365a4fe069f01829fe0dea448d7f7 646 Gene3D G3DSA:3.30.565.10 45 240 3.7E-48 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS01635 0ce365a4fe069f01829fe0dea448d7f7 646 SUPERFAMILY SSF55874 21 232 1.92E-60 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS03945 a0be8819a25720f93e1123a2e9ce9360 197 Pfam PF04289 Protein of unknown function (DUF447) 4 176 3.5E-49 T 29-03-2018 IPR007386 Protein of unknown function DUF447 GBCGDNIH2_RS03945 a0be8819a25720f93e1123a2e9ce9360 197 Gene3D G3DSA:1.20.58.290 118 180 2.8E-29 T 29-03-2018 GBCGDNIH2_RS03945 a0be8819a25720f93e1123a2e9ce9360 197 Gene3D G3DSA:2.30.110.10 1 117 8.0E-17 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 GBCGDNIH2_RS03945 a0be8819a25720f93e1123a2e9ce9360 197 SUPERFAMILY SSF50475 1 178 1.9E-53 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 GBCGDNIH2_RS11880 bde3a65acf06783cef2aab41e026ec1d 457 Pfam PF13360 PQQ-like domain 139 376 1.7E-52 T 29-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat GBCGDNIH2_RS11880 bde3a65acf06783cef2aab41e026ec1d 457 Pfam PF13360 PQQ-like domain 382 456 1.4E-4 T 29-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat GBCGDNIH2_RS11880 bde3a65acf06783cef2aab41e026ec1d 457 SUPERFAMILY SSF50998 80 456 5.1E-72 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily GBCGDNIH2_RS11880 bde3a65acf06783cef2aab41e026ec1d 457 SMART SM00564 257 289 670.0 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat GBCGDNIH2_RS11880 bde3a65acf06783cef2aab41e026ec1d 457 SMART SM00564 309 340 2.2 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat GBCGDNIH2_RS11880 bde3a65acf06783cef2aab41e026ec1d 457 SMART SM00564 212 244 0.0028 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat GBCGDNIH2_RS11880 bde3a65acf06783cef2aab41e026ec1d 457 SMART SM00564 126 157 0.37 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat GBCGDNIH2_RS11880 bde3a65acf06783cef2aab41e026ec1d 457 SMART SM00564 347 378 430.0 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat GBCGDNIH2_RS11880 bde3a65acf06783cef2aab41e026ec1d 457 SMART SM00564 172 204 0.55 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat GBCGDNIH2_RS11880 bde3a65acf06783cef2aab41e026ec1d 457 Gene3D G3DSA:2.140.10.10 74 250 8.1E-30 T 29-03-2018 GBCGDNIH2_RS11880 bde3a65acf06783cef2aab41e026ec1d 457 Gene3D G3DSA:2.140.10.10 251 386 1.1E-17 T 29-03-2018 GBCGDNIH2_RS02945 ea50e01be420275bfdce374af572f1cc 125 Gene3D G3DSA:4.10.910.10 68 86 1.7E-19 T 29-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02945 ea50e01be420275bfdce374af572f1cc 125 PIRSF PIRSF002134 1 125 7.7E-46 T 29-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02945 ea50e01be420275bfdce374af572f1cc 125 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 120 28.995 T 29-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02945 ea50e01be420275bfdce374af572f1cc 125 Pfam PF00416 Ribosomal protein S13/S18 3 109 2.0E-31 T 29-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02945 ea50e01be420275bfdce374af572f1cc 125 Gene3D G3DSA:1.10.8.50 1 67 2.4E-23 T 29-03-2018 GBCGDNIH2_RS02945 ea50e01be420275bfdce374af572f1cc 125 ProSitePatterns PS00646 Ribosomal protein S13 signature. 88 101 - T 29-03-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02945 ea50e01be420275bfdce374af572f1cc 125 SUPERFAMILY SSF46946 2 122 1.3E-46 T 29-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 GBCGDNIH2_RS02945 ea50e01be420275bfdce374af572f1cc 125 Gene3D G3DSA:4.10.910.10 87 122 1.0E-28 T 29-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02945 ea50e01be420275bfdce374af572f1cc 125 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 114 2.1E-54 T 29-03-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS05150 6a8a49ed6c41f25fdc317449d64007b6 131 ProSitePatterns PS00935 Glyoxalase I signature 2. 73 85 - T 29-03-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 GBCGDNIH2_RS05150 6a8a49ed6c41f25fdc317449d64007b6 131 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 127 2.7E-21 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain GBCGDNIH2_RS05150 6a8a49ed6c41f25fdc317449d64007b6 131 TIGRFAM TIGR00068 glyox_I: lactoylglutathione lyase 5 130 8.2E-58 T 29-03-2018 IPR004361 Glyoxalase I GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 GBCGDNIH2_RS05150 6a8a49ed6c41f25fdc317449d64007b6 131 ProSitePatterns PS00934 Glyoxalase I signature 1. 8 29 - T 29-03-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 GBCGDNIH2_RS05150 6a8a49ed6c41f25fdc317449d64007b6 131 Gene3D G3DSA:3.10.180.10 4 131 9.0E-36 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase GBCGDNIH2_RS05150 6a8a49ed6c41f25fdc317449d64007b6 131 SUPERFAMILY SSF54593 4 131 5.64E-35 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase GBCGDNIH2_RS08445 9dd234f1ce1bf962ad0960cd3c619388 204 SUPERFAMILY SSF51735 2 203 1.8E-39 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS08445 9dd234f1ce1bf962ad0960cd3c619388 204 Gene3D G3DSA:3.40.50.720 1 204 2.9E-24 T 29-03-2018 GBCGDNIH2_RS08445 9dd234f1ce1bf962ad0960cd3c619388 204 Pfam PF13460 NAD(P)H-binding 8 193 6.5E-29 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS11390 a5f3afa1cccea97db41b28588b900e7c 286 SMART SM00650 44 216 1.4E-67 T 29-03-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 GBCGDNIH2_RS11390 a5f3afa1cccea97db41b28588b900e7c 286 SUPERFAMILY SSF53335 24 280 4.56E-69 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GBCGDNIH2_RS11390 a5f3afa1cccea97db41b28588b900e7c 286 Pfam PF00398 Ribosomal RNA adenine dimethylase 29 276 1.0E-50 T 29-03-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm GBCGDNIH2_RS11390 a5f3afa1cccea97db41b28588b900e7c 286 Gene3D G3DSA:3.40.50.150 20 227 2.0E-56 T 29-03-2018 GBCGDNIH2_RS11390 a5f3afa1cccea97db41b28588b900e7c 286 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 29 279 9.6E-74 T 29-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 GBCGDNIH2_RS11390 a5f3afa1cccea97db41b28588b900e7c 286 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 60 88 - T 29-03-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 GBCGDNIH2_RS11390 a5f3afa1cccea97db41b28588b900e7c 286 Gene3D G3DSA:1.10.8.100 228 280 3.9E-16 T 29-03-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 GBCGDNIH2_RS11390 a5f3afa1cccea97db41b28588b900e7c 286 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 28 282 50.081 T 29-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 GBCGDNIH2_RS11360 718a244a9912aaf5bfa496ea56d5ae80 322 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 94 116 - T 29-03-2018 IPR030470 UbiA prenyltransferase conserved site GBCGDNIH2_RS11360 718a244a9912aaf5bfa496ea56d5ae80 322 Pfam PF01040 UbiA prenyltransferase family 55 299 3.9E-42 T 29-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 GBCGDNIH2_RS11360 718a244a9912aaf5bfa496ea56d5ae80 322 Hamap MF_01635 4-hydroxybenzoate octaprenyltransferase [ubiA]. 31 318 25.102 T 29-03-2018 IPR031103 4-hydroxybenzoate octaprenyltransferase GO:0004659|GO:0006744|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 GBCGDNIH2_RS11360 718a244a9912aaf5bfa496ea56d5ae80 322 TIGRFAM TIGR01474 ubiA_proteo: 4-hydroxybenzoate polyprenyl transferase 37 317 5.3E-86 T 29-03-2018 IPR006370 4-hydroxybenzoate polyprenyltransferase GO:0004659|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 GBCGDNIH2_RS10145 071423b78ea2d43811abb9f691fc5fd1 404 SUPERFAMILY SSF53383 7 392 1.3E-96 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase GBCGDNIH2_RS10145 071423b78ea2d43811abb9f691fc5fd1 404 Gene3D G3DSA:3.90.1150.10 265 383 3.3E-27 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 GBCGDNIH2_RS10145 071423b78ea2d43811abb9f691fc5fd1 404 Gene3D G3DSA:3.40.640.10 17 264 4.2E-59 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GBCGDNIH2_RS10145 071423b78ea2d43811abb9f691fc5fd1 404 Pfam PF00266 Aminotransferase class-V 10 382 1.0E-73 T 29-03-2018 IPR000192 Aminotransferase class V domain GBCGDNIH2_RS10145 071423b78ea2d43811abb9f691fc5fd1 404 PIRSF PIRSF005572 6 396 3.8E-115 T 29-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 GBCGDNIH2_RS10145 071423b78ea2d43811abb9f691fc5fd1 404 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 205 224 - T 29-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site GBCGDNIH2_RS06385 7a990ac96ab1e71eb4d0433149b54024 455 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 GBCGDNIH2_RS06385 7a990ac96ab1e71eb4d0433149b54024 455 Gene3D G3DSA:3.40.50.920 322 452 2.6E-44 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 GBCGDNIH2_RS06385 7a990ac96ab1e71eb4d0433149b54024 455 Gene3D G3DSA:3.40.50.970 127 321 4.4E-81 T 29-03-2018 GBCGDNIH2_RS06385 7a990ac96ab1e71eb4d0433149b54024 455 SUPERFAMILY SSF52518 130 320 1.34E-69 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold GBCGDNIH2_RS06385 7a990ac96ab1e71eb4d0433149b54024 455 SUPERFAMILY SSF52922 315 450 3.66E-43 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 GBCGDNIH2_RS06385 7a990ac96ab1e71eb4d0433149b54024 455 Pfam PF00364 Biotin-requiring enzyme 4 77 2.6E-21 T 29-03-2018 IPR000089 Biotin/lipoyl attachment GBCGDNIH2_RS06385 7a990ac96ab1e71eb4d0433149b54024 455 Pfam PF02780 Transketolase, C-terminal domain 321 441 1.2E-40 T 29-03-2018 IPR033248 Transketolase, C-terminal domain GBCGDNIH2_RS06385 7a990ac96ab1e71eb4d0433149b54024 455 SMART SM00861 131 306 1.2E-64 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain GBCGDNIH2_RS06385 7a990ac96ab1e71eb4d0433149b54024 455 Pfam PF02779 Transketolase, pyrimidine binding domain 130 305 6.0E-52 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain GBCGDNIH2_RS06385 7a990ac96ab1e71eb4d0433149b54024 455 Gene3D G3DSA:2.40.50.100 2 81 5.3E-19 T 29-03-2018 GBCGDNIH2_RS06385 7a990ac96ab1e71eb4d0433149b54024 455 SUPERFAMILY SSF51230 1 95 5.89E-28 T 29-03-2018 IPR011053 Single hybrid motif GBCGDNIH2_RS02850 20c6fc45f95642525eb1ed7ecd5b31cf 276 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 273 47.042 T 29-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 GBCGDNIH2_RS02850 20c6fc45f95642525eb1ed7ecd5b31cf 276 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 29-03-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02850 20c6fc45f95642525eb1ed7ecd5b31cf 276 Gene3D G3DSA:2.30.30.30 119 195 1.8E-32 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 GBCGDNIH2_RS02850 20c6fc45f95642525eb1ed7ecd5b31cf 276 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 273 1.7E-128 T 29-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 GBCGDNIH2_RS02850 20c6fc45f95642525eb1ed7ecd5b31cf 276 SUPERFAMILY SSF50104 126 272 1.44E-61 T 29-03-2018 IPR008991 Translation protein SH3-like domain GBCGDNIH2_RS02850 20c6fc45f95642525eb1ed7ecd5b31cf 276 SUPERFAMILY SSF50249 2 125 9.25E-48 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold GBCGDNIH2_RS02850 20c6fc45f95642525eb1ed7ecd5b31cf 276 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 125 250 4.0E-57 T 29-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 GBCGDNIH2_RS02850 20c6fc45f95642525eb1ed7ecd5b31cf 276 Gene3D G3DSA:2.40.50.140 1 114 1.2E-46 T 29-03-2018 GBCGDNIH2_RS02850 20c6fc45f95642525eb1ed7ecd5b31cf 276 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 118 1.7E-32 T 29-03-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS02850 20c6fc45f95642525eb1ed7ecd5b31cf 276 Gene3D G3DSA:4.10.950.10 197 273 8.6E-36 T 29-03-2018 IPR014726 Ribosomal protein L2, domain 3 GBCGDNIH2_RS02850 20c6fc45f95642525eb1ed7ecd5b31cf 276 PIRSF PIRSF002158 5 275 8.5E-103 T 29-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS02850 20c6fc45f95642525eb1ed7ecd5b31cf 276 SMART SM01383 42 118 6.2E-44 T 29-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS02850 20c6fc45f95642525eb1ed7ecd5b31cf 276 SMART SM01382 124 252 1.8E-91 T 29-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 GBCGDNIH2_RS00645 8d89bcf129d2f4082ec19a4d7ed92832 192 Pfam PF00578 AhpC/TSA family 56 166 4.7E-15 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 GBCGDNIH2_RS00645 8d89bcf129d2f4082ec19a4d7ed92832 192 ProSitePatterns PS00194 Thioredoxin family active site. 80 98 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 GBCGDNIH2_RS00645 8d89bcf129d2f4082ec19a4d7ed92832 192 Gene3D G3DSA:3.40.30.10 31 192 6.2E-30 T 29-03-2018 GBCGDNIH2_RS00645 8d89bcf129d2f4082ec19a4d7ed92832 192 SUPERFAMILY SSF52833 32 190 2.27E-32 T 29-03-2018 IPR012336 Thioredoxin-like fold GBCGDNIH2_RS09185 c525f589cc8da620be8aa1e22013ff1d 371 Pfam PF13579 Glycosyl transferase 4-like domain 21 166 9.1E-19 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 GBCGDNIH2_RS09185 c525f589cc8da620be8aa1e22013ff1d 371 Gene3D G3DSA:3.40.50.2000 183 354 9.5E-49 T 29-03-2018 GBCGDNIH2_RS09185 c525f589cc8da620be8aa1e22013ff1d 371 SUPERFAMILY SSF53756 15 368 9.14E-82 T 29-03-2018 GBCGDNIH2_RS09185 c525f589cc8da620be8aa1e22013ff1d 371 Gene3D G3DSA:3.40.50.2000 15 182 5.6E-29 T 29-03-2018 GBCGDNIH2_RS09185 c525f589cc8da620be8aa1e22013ff1d 371 Pfam PF00534 Glycosyl transferases group 1 182 351 9.3E-33 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 GBCGDNIH2_RS01255 9e373c742b3437ca3492090b26724df0 423 Gene3D G3DSA:3.40.50.2000 187 351 3.7E-33 T 29-03-2018 GBCGDNIH2_RS01255 9e373c742b3437ca3492090b26724df0 423 SUPERFAMILY SSF53756 21 366 7.46E-48 T 29-03-2018 GBCGDNIH2_RS01255 9e373c742b3437ca3492090b26724df0 423 Gene3D G3DSA:3.40.50.2000 6 186 4.3E-4 T 29-03-2018 GBCGDNIH2_RS01255 9e373c742b3437ca3492090b26724df0 423 Pfam PF13439 Glycosyltransferase Family 4 24 172 2.1E-7 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 GBCGDNIH2_RS01255 9e373c742b3437ca3492090b26724df0 423 Pfam PF00534 Glycosyl transferases group 1 182 346 4.9E-17 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 GBCGDNIH2_RS09710 4ecec0f50d74dc599bb07b0c8cbdb908 416 SUPERFAMILY SSF102114 96 295 1.44E-13 T 29-03-2018 GBCGDNIH2_RS09710 4ecec0f50d74dc599bb07b0c8cbdb908 416 Gene3D G3DSA:3.20.20.70 65 410 8.7E-28 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS09710 4ecec0f50d74dc599bb07b0c8cbdb908 416 Pfam PF04055 Radical SAM superfamily 99 277 2.8E-17 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 GBCGDNIH2_RS09710 4ecec0f50d74dc599bb07b0c8cbdb908 416 SMART SM00729 95 320 1.5E-5 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 GBCGDNIH2_RS00485 3b042f0629ab087f542a14e36d2e4860 190 Pfam PF01923 Cobalamin adenosyltransferase 8 171 6.5E-54 T 29-03-2018 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 GBCGDNIH2_RS00485 3b042f0629ab087f542a14e36d2e4860 190 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 14 181 2.0E-31 T 29-03-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 GBCGDNIH2_RS00485 3b042f0629ab087f542a14e36d2e4860 190 Gene3D G3DSA:1.20.1200.10 17 187 1.5E-55 T 29-03-2018 GBCGDNIH2_RS00485 3b042f0629ab087f542a14e36d2e4860 190 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 9 175 8.7E-51 T 29-03-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 GBCGDNIH2_RS00485 3b042f0629ab087f542a14e36d2e4860 190 SUPERFAMILY SSF89028 7 180 6.08E-53 T 29-03-2018 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 GBCGDNIH2_RS03335 8737b3c72d7e2323f3777d1dfd9009d9 207 Gene3D G3DSA:3.40.50.300 15 207 7.0E-74 T 29-03-2018 GBCGDNIH2_RS03335 8737b3c72d7e2323f3777d1dfd9009d9 207 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 35 207 1.3E-71 T 29-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 GBCGDNIH2_RS03335 8737b3c72d7e2323f3777d1dfd9009d9 207 Pfam PF12557 Cob(I)alamin adenosyltransferase N terminal 3 30 1.9E-8 T 29-03-2018 IPR025826 Cob(I)alamin adenosyltransferase N-terminal domain KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 GBCGDNIH2_RS03335 8737b3c72d7e2323f3777d1dfd9009d9 207 PIRSF PIRSF015617 10 207 5.0E-73 T 29-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 GBCGDNIH2_RS03335 8737b3c72d7e2323f3777d1dfd9009d9 207 SUPERFAMILY SSF52540 17 207 1.0E-71 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS03335 8737b3c72d7e2323f3777d1dfd9009d9 207 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 36 207 1.6E-62 T 29-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 GBCGDNIH2_RS03345 0cab2f899193dec31f526e6bdabeacab 354 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 8 212 1.7E-54 T 29-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain GBCGDNIH2_RS03345 0cab2f899193dec31f526e6bdabeacab 354 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 256 343 6.2E-15 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal GBCGDNIH2_RS03345 0cab2f899193dec31f526e6bdabeacab 354 SMART SM00833 254 347 2.8E-4 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal GBCGDNIH2_RS03345 0cab2f899193dec31f526e6bdabeacab 354 SUPERFAMILY SSF52540 6 210 1.96E-30 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS03345 0cab2f899193dec31f526e6bdabeacab 354 TIGRFAM TIGR02475 CobW: cobalamin biosynthesis protein CobW 7 343 2.0E-158 T 29-03-2018 IPR012824 Cobalamin (vitamin B12) biosynthesis CobW GO:0009236 GBCGDNIH2_RS03345 0cab2f899193dec31f526e6bdabeacab 354 SUPERFAMILY SSF90002 254 343 1.96E-17 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal GBCGDNIH2_RS03345 0cab2f899193dec31f526e6bdabeacab 354 Gene3D G3DSA:3.30.1220.10 233 345 3.0E-19 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal GBCGDNIH2_RS03345 0cab2f899193dec31f526e6bdabeacab 354 Gene3D G3DSA:3.40.50.300 4 230 3.9E-40 T 29-03-2018 GBCGDNIH2_RS08725 54f3c91607043eb76629cd31057ed25f 521 SMART SM00387 363 485 7.5E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS08725 54f3c91607043eb76629cd31057ed25f 521 Pfam PF00512 His Kinase A (phospho-acceptor) domain 258 316 2.4E-7 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GBCGDNIH2_RS08725 54f3c91607043eb76629cd31057ed25f 521 SMART SM00304 197 250 4.5E-5 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 GBCGDNIH2_RS08725 54f3c91607043eb76629cd31057ed25f 521 SMART SM00388 251 316 5.4E-6 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GBCGDNIH2_RS08725 54f3c91607043eb76629cd31057ed25f 521 Gene3D G3DSA:3.30.565.10 310 485 7.2E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS08725 54f3c91607043eb76629cd31057ed25f 521 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 364 481 2.7E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS08725 54f3c91607043eb76629cd31057ed25f 521 Gene3D G3DSA:1.10.287.130 241 309 2.2E-7 T 29-03-2018 GBCGDNIH2_RS08725 54f3c91607043eb76629cd31057ed25f 521 SUPERFAMILY SSF47384 234 317 8.44E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GBCGDNIH2_RS08725 54f3c91607043eb76629cd31057ed25f 521 PRINTS PR00344 Bacterial sensor protein C-terminal signature 434 452 7.6E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS08725 54f3c91607043eb76629cd31057ed25f 521 PRINTS PR00344 Bacterial sensor protein C-terminal signature 401 415 7.6E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS08725 54f3c91607043eb76629cd31057ed25f 521 SUPERFAMILY SSF55874 307 459 3.01E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS00385 f2acdf62fb0f89a606898f9165b3ade6 425 Pfam PF00355 Rieske [2Fe-2S] domain 47 126 1.3E-13 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 GBCGDNIH2_RS00385 f2acdf62fb0f89a606898f9165b3ade6 425 Gene3D G3DSA:3.90.380.10 147 424 5.3E-59 T 29-03-2018 GBCGDNIH2_RS00385 f2acdf62fb0f89a606898f9165b3ade6 425 Gene3D G3DSA:2.102.10.10 40 146 2.5E-17 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 GBCGDNIH2_RS00385 f2acdf62fb0f89a606898f9165b3ade6 425 SUPERFAMILY SSF55961 163 221 3.69E-47 T 29-03-2018 GBCGDNIH2_RS00385 f2acdf62fb0f89a606898f9165b3ade6 425 SUPERFAMILY SSF55961 248 416 3.69E-47 T 29-03-2018 GBCGDNIH2_RS00385 f2acdf62fb0f89a606898f9165b3ade6 425 SUPERFAMILY SSF50022 18 158 6.15E-43 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 GBCGDNIH2_RS00385 f2acdf62fb0f89a606898f9165b3ade6 425 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 62 77 1.8E-17 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 GBCGDNIH2_RS00385 f2acdf62fb0f89a606898f9165b3ade6 425 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 32 57 1.8E-17 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 GBCGDNIH2_RS00385 f2acdf62fb0f89a606898f9165b3ade6 425 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 83 103 1.8E-17 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 GBCGDNIH2_RS00385 f2acdf62fb0f89a606898f9165b3ade6 425 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 143 169 1.8E-17 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 GBCGDNIH2_RS00385 f2acdf62fb0f89a606898f9165b3ade6 425 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 181 203 1.8E-17 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 GBCGDNIH2_RS00385 f2acdf62fb0f89a606898f9165b3ade6 425 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 104 124 1.8E-17 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 GBCGDNIH2_RS00385 f2acdf62fb0f89a606898f9165b3ade6 425 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 191 417 3.3E-44 T 29-03-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 GBCGDNIH2_RS03365 274fb29b0ad2954e8594c77ed726aaed 254 PIRSF PIRSF036427 14 253 1.2E-64 T 29-03-2018 IPR012382 Precorrin-2 C(20)-methyltransferase GO:0008757|GO:0009236|GO:0030788 GBCGDNIH2_RS03365 274fb29b0ad2954e8594c77ed726aaed 254 Gene3D G3DSA:3.40.1010.10 15 167 1.5E-24 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GBCGDNIH2_RS03365 274fb29b0ad2954e8594c77ed726aaed 254 SUPERFAMILY SSF53790 14 252 7.46E-45 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GBCGDNIH2_RS03365 274fb29b0ad2954e8594c77ed726aaed 254 TIGRFAM TIGR01467 cobI_cbiL: precorrin-2 C(20)-methyltransferase 16 248 5.1E-65 T 29-03-2018 IPR006364 Precorrin-2 C(20)-methyltransferase domain GO:0008757|GO:0009236 GBCGDNIH2_RS03365 274fb29b0ad2954e8594c77ed726aaed 254 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 17 229 2.8E-41 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GBCGDNIH2_RS08875 a232d410570b0809d477e932d4dfec7e 270 SUPERFAMILY SSF143631 13 239 6.41E-42 T 29-03-2018 IPR003374 ApbE-like domain GBCGDNIH2_RS08875 a232d410570b0809d477e932d4dfec7e 270 Gene3D G3DSA:3.10.520.10 21 246 1.7E-23 T 29-03-2018 GBCGDNIH2_RS08875 a232d410570b0809d477e932d4dfec7e 270 Pfam PF02424 ApbE family 20 240 1.1E-28 T 29-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 GBCGDNIH2_RS11990 39fe6e393d1ae727889e11f35038d3a1 213 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 29 97 2.0E-20 T 29-03-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 GBCGDNIH2_RS11990 39fe6e393d1ae727889e11f35038d3a1 213 Pfam PF01386 Ribosomal L25p family 7 94 5.0E-24 T 29-03-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 GBCGDNIH2_RS11990 39fe6e393d1ae727889e11f35038d3a1 213 Gene3D G3DSA:2.40.240.10 4 97 4.8E-28 T 29-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 GBCGDNIH2_RS11990 39fe6e393d1ae727889e11f35038d3a1 213 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 102 187 2.9E-23 T 29-03-2018 IPR020057 Ribosomal protein L25, beta domain GBCGDNIH2_RS11990 39fe6e393d1ae727889e11f35038d3a1 213 Gene3D G3DSA:2.170.120.20 101 192 1.7E-23 T 29-03-2018 IPR020057 Ribosomal protein L25, beta domain GBCGDNIH2_RS11990 39fe6e393d1ae727889e11f35038d3a1 213 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 8 185 1.3E-40 T 29-03-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 GBCGDNIH2_RS11990 39fe6e393d1ae727889e11f35038d3a1 213 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 5 186 26.773 T 29-03-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 GBCGDNIH2_RS11990 39fe6e393d1ae727889e11f35038d3a1 213 SUPERFAMILY SSF50715 5 193 5.23E-51 T 29-03-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 GBCGDNIH2_RS07140 47edff2c23cc3e3ed75fd65d81b624fc 188 SMART SM00972 124 185 3.8E-19 T 29-03-2018 IPR007893 Spore coat protein U GBCGDNIH2_RS07140 47edff2c23cc3e3ed75fd65d81b624fc 188 Pfam PF05229 Spore Coat Protein U domain 56 185 1.6E-27 T 29-03-2018 IPR007893 Spore coat protein U GBCGDNIH2_RS07145 cf968c76998443cc6b67ef20a485d816 380 Pfam PF07690 Major Facilitator Superfamily 14 342 5.7E-23 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 GBCGDNIH2_RS07145 cf968c76998443cc6b67ef20a485d816 380 SUPERFAMILY SSF103473 14 376 3.53E-32 T 29-03-2018 IPR020846 Major facilitator superfamily domain GBCGDNIH2_RS07145 cf968c76998443cc6b67ef20a485d816 380 Gene3D G3DSA:1.20.1250.20 4 186 4.0E-15 T 29-03-2018 GBCGDNIH2_RS07145 cf968c76998443cc6b67ef20a485d816 380 Gene3D G3DSA:1.20.1250.20 197 380 6.1E-13 T 29-03-2018 GBCGDNIH2_RS03960 a090f8aadb2067cc70fe066c196561a2 231 Pfam PF00977 Histidine biosynthesis protein 3 224 8.5E-27 T 29-03-2018 IPR006062 Histidine biosynthesis GO:0000105 GBCGDNIH2_RS03960 a090f8aadb2067cc70fe066c196561a2 231 SUPERFAMILY SSF51366 2 229 6.8E-30 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 GBCGDNIH2_RS03960 a090f8aadb2067cc70fe066c196561a2 231 Gene3D G3DSA:3.20.20.70 1 231 5.1E-19 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS05590 6cb47e7de2a328caa042225d196559d8 249 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 37 224 1.9E-51 T 29-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 GBCGDNIH2_RS05590 6cb47e7de2a328caa042225d196559d8 249 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 36 248 45.213 T 29-03-2018 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 GBCGDNIH2_RS05590 6cb47e7de2a328caa042225d196559d8 249 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 183 204 - T 29-03-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 GBCGDNIH2_RS05590 6cb47e7de2a328caa042225d196559d8 249 Gene3D G3DSA:3.40.190.10 32 155 4.4E-33 T 29-03-2018 GBCGDNIH2_RS05590 6cb47e7de2a328caa042225d196559d8 249 SUPERFAMILY SSF53850 37 245 1.32E-58 T 29-03-2018 GBCGDNIH2_RS05590 6cb47e7de2a328caa042225d196559d8 249 Pfam PF01634 ATP phosphoribosyltransferase 88 244 4.9E-43 T 29-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 GBCGDNIH2_RS05590 6cb47e7de2a328caa042225d196559d8 249 Gene3D G3DSA:3.40.190.10 156 249 4.6E-18 T 29-03-2018 GBCGDNIH2_RS02020 ea3348948dc411dd89c2daebe3c493b4 184 SUPERFAMILY SSF46785 35 163 5.36E-35 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS02020 ea3348948dc411dd89c2daebe3c493b4 184 Gene3D G3DSA:1.10.10.10 21 115 3.0E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS02020 ea3348948dc411dd89c2daebe3c493b4 184 Pfam PF01475 Ferric uptake regulator family 42 160 5.5E-33 T 29-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 GBCGDNIH2_RS11045 25c254bd6a3dd5804bfd3e7c187a77ce 57 PIRSF PIRSF036466 1 55 2.2E-19 T 29-03-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 GBCGDNIH2_RS11045 25c254bd6a3dd5804bfd3e7c187a77ce 57 Hamap MF_01361 UPF0391 membrane protein YtjA [ytjA]. 1 56 18.495 T 29-03-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 GBCGDNIH2_RS11045 25c254bd6a3dd5804bfd3e7c187a77ce 57 Pfam PF07043 Protein of unknown function (DUF1328) 6 44 2.2E-15 T 29-03-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 GBCGDNIH2_RS00435 99f1e12672f9527200e6351f1f91ee31 422 Gene3D G3DSA:3.40.50.300 15 299 4.7E-64 T 29-03-2018 GBCGDNIH2_RS00435 99f1e12672f9527200e6351f1f91ee31 422 ProSitePatterns PS00211 ABC transporters family signature. 186 200 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GBCGDNIH2_RS00435 99f1e12672f9527200e6351f1f91ee31 422 Pfam PF00005 ABC transporter 63 213 6.2E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GBCGDNIH2_RS00435 99f1e12672f9527200e6351f1f91ee31 422 TIGRFAM TIGR03415 ABC_choXWV_ATP: choline ABC transporter, ATP-binding protein 18 406 3.8E-156 T 29-03-2018 IPR022473 ABC transporter, Choline, ATP-binding subunit GO:0015220|GO:0015871|GO:0055052 GBCGDNIH2_RS00435 99f1e12672f9527200e6351f1f91ee31 422 SUPERFAMILY SSF52540 60 292 1.26E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS00435 99f1e12672f9527200e6351f1f91ee31 422 SMART SM00382 69 271 3.2E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS02795 8eeda3bf0e4ea8792beb4f428e3f034a 172 SUPERFAMILY SSF160369 3 168 4.05E-55 T 29-03-2018 GBCGDNIH2_RS02795 8eeda3bf0e4ea8792beb4f428e3f034a 172 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 1 141 4.0E-5 T 29-03-2018 GBCGDNIH2_RS02795 8eeda3bf0e4ea8792beb4f428e3f034a 172 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 1 158 25.916 T 29-03-2018 IPR022973 Ribosomal protein L10 GBCGDNIH2_RS02795 8eeda3bf0e4ea8792beb4f428e3f034a 172 Pfam PF00466 Ribosomal protein L10 3 98 1.5E-24 T 29-03-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 GBCGDNIH2_RS09205 d2bcd623f1b4f4cc110825733787d4f0 600 Gene3D G3DSA:3.40.50.300 318 599 5.0E-61 T 29-03-2018 GBCGDNIH2_RS09205 d2bcd623f1b4f4cc110825733787d4f0 600 Gene3D G3DSA:3.30.450.90 176 316 7.0E-45 T 29-03-2018 GBCGDNIH2_RS09205 d2bcd623f1b4f4cc110825733787d4f0 600 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 411 425 - T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 GBCGDNIH2_RS09205 d2bcd623f1b4f4cc110825733787d4f0 600 SUPERFAMILY SSF160246 36 173 6.02E-26 T 29-03-2018 GBCGDNIH2_RS09205 d2bcd623f1b4f4cc110825733787d4f0 600 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 72 177 1.1E-16 T 29-03-2018 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 GBCGDNIH2_RS09205 d2bcd623f1b4f4cc110825733787d4f0 600 SUPERFAMILY SSF52540 199 591 3.11E-100 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS09205 d2bcd623f1b4f4cc110825733787d4f0 600 Pfam PF00437 Type II/IV secretion system protein 215 483 9.1E-85 T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 GBCGDNIH2_RS09205 d2bcd623f1b4f4cc110825733787d4f0 600 SMART SM00382 344 467 3.2E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS04095 75bdef6c606eaf2c99afbcef1871c2c9 368 Gene3D G3DSA:2.70.98.10 28 368 7.9E-97 T 29-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 GBCGDNIH2_RS04095 75bdef6c606eaf2c99afbcef1871c2c9 368 Pfam PF01263 Aldose 1-epimerase 43 363 3.4E-70 T 29-03-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 GBCGDNIH2_RS04095 75bdef6c606eaf2c99afbcef1871c2c9 368 SUPERFAMILY SSF74650 28 365 4.27E-96 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 GBCGDNIH2_RS04095 75bdef6c606eaf2c99afbcef1871c2c9 368 PIRSF PIRSF005096 21 368 8.7E-120 T 29-03-2018 IPR015443 Aldose 1-epimerase GO:0016853|GO:0019318 KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317 GBCGDNIH2_RS06265 540db5ff5bbc7c8c878a2e9318f9c953 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 6.0E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS06265 540db5ff5bbc7c8c878a2e9318f9c953 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 6.0E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS06265 540db5ff5bbc7c8c878a2e9318f9c953 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 6.0E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS06265 540db5ff5bbc7c8c878a2e9318f9c953 271 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 GBCGDNIH2_RS06265 540db5ff5bbc7c8c878a2e9318f9c953 271 Gene3D G3DSA:3.40.50.720 2 266 1.3E-45 T 29-03-2018 GBCGDNIH2_RS06265 540db5ff5bbc7c8c878a2e9318f9c953 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 5.2E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS06265 540db5ff5bbc7c8c878a2e9318f9c953 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 5.2E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS06265 540db5ff5bbc7c8c878a2e9318f9c953 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 5.2E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS06265 540db5ff5bbc7c8c878a2e9318f9c953 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 5.2E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS06265 540db5ff5bbc7c8c878a2e9318f9c953 271 Pfam PF00106 short chain dehydrogenase 11 197 3.9E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS06265 540db5ff5bbc7c8c878a2e9318f9c953 271 PIRSF PIRSF000126 1 267 2.4E-63 T 29-03-2018 GBCGDNIH2_RS06265 540db5ff5bbc7c8c878a2e9318f9c953 271 SUPERFAMILY SSF51735 7 231 3.66E-53 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS03495 a14953e77f879d6776d83d6bcaeede61 177 Gene3D G3DSA:1.20.1260.10 4 176 1.9E-45 T 29-03-2018 IPR012347 Ferritin-related GBCGDNIH2_RS03495 a14953e77f879d6776d83d6bcaeede61 177 SUPERFAMILY SSF47240 16 172 4.14E-46 T 29-03-2018 IPR009078 Ferritin-like superfamily GBCGDNIH2_RS03495 a14953e77f879d6776d83d6bcaeede61 177 ProSitePatterns PS00818 Dps protein family signature 1. 53 69 - T 29-03-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 GBCGDNIH2_RS03495 a14953e77f879d6776d83d6bcaeede61 177 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 149 167 2.6E-12 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 GBCGDNIH2_RS03495 a14953e77f879d6776d83d6bcaeede61 177 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 77 93 2.6E-12 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 GBCGDNIH2_RS03495 a14953e77f879d6776d83d6bcaeede61 177 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 53 69 2.6E-12 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 GBCGDNIH2_RS03495 a14953e77f879d6776d83d6bcaeede61 177 Pfam PF00210 Ferritin-like domain 32 173 3.5E-26 T 29-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 GBCGDNIH2_RS03495 a14953e77f879d6776d83d6bcaeede61 177 PIRSF PIRSF005900 10 176 1.6E-43 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 GBCGDNIH2_RS00800 51243bcb1a11949dd625755e815fae66 265 Gene3D G3DSA:3.40.50.150 13 262 4.2E-44 T 29-03-2018 GBCGDNIH2_RS00800 51243bcb1a11949dd625755e815fae66 265 Pfam PF01209 ubiE/COQ5 methyltransferase family 37 263 4.0E-83 T 29-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 GBCGDNIH2_RS00800 51243bcb1a11949dd625755e815fae66 265 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 41 263 4.7E-78 T 29-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 GBCGDNIH2_RS00800 51243bcb1a11949dd625755e815fae66 265 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 32 264 36.376 T 29-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 GBCGDNIH2_RS00800 51243bcb1a11949dd625755e815fae66 265 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 52 67 - T 29-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 GBCGDNIH2_RS00800 51243bcb1a11949dd625755e815fae66 265 SUPERFAMILY SSF53335 37 261 2.79E-44 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GBCGDNIH2_RS05535 d640720b25ceb6f5cc9f1b66302c66ef 506 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 294 305 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 GBCGDNIH2_RS05535 d640720b25ceb6f5cc9f1b66302c66ef 506 Gene3D G3DSA:3.40.309.10 279 480 8.4E-65 T 29-03-2018 GBCGDNIH2_RS05535 d640720b25ceb6f5cc9f1b66302c66ef 506 SUPERFAMILY SSF53720 12 498 4.45E-161 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 GBCGDNIH2_RS05535 d640720b25ceb6f5cc9f1b66302c66ef 506 Pfam PF00171 Aldehyde dehydrogenase family 27 493 9.6E-164 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 GBCGDNIH2_RS05535 d640720b25ceb6f5cc9f1b66302c66ef 506 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 261 268 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 GBCGDNIH2_RS05535 d640720b25ceb6f5cc9f1b66302c66ef 506 Gene3D G3DSA:3.40.605.10 6 278 3.7E-95 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 GBCGDNIH2_RS03805 41b9b02edd246f00118ab1cb32e1a8c3 477 SUPERFAMILY SSF47384 252 322 9.61E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GBCGDNIH2_RS03805 41b9b02edd246f00118ab1cb32e1a8c3 477 PRINTS PR00344 Bacterial sensor protein C-terminal signature 439 457 7.0E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS03805 41b9b02edd246f00118ab1cb32e1a8c3 477 PRINTS PR00344 Bacterial sensor protein C-terminal signature 463 476 7.0E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS03805 41b9b02edd246f00118ab1cb32e1a8c3 477 PRINTS PR00344 Bacterial sensor protein C-terminal signature 404 418 7.0E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS03805 41b9b02edd246f00118ab1cb32e1a8c3 477 PRINTS PR00344 Bacterial sensor protein C-terminal signature 422 432 7.0E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS03805 41b9b02edd246f00118ab1cb32e1a8c3 477 SMART SM00388 268 326 0.0019 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GBCGDNIH2_RS03805 41b9b02edd246f00118ab1cb32e1a8c3 477 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 373 476 6.1E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS03805 41b9b02edd246f00118ab1cb32e1a8c3 477 SUPERFAMILY SSF55874 327 477 7.07E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS03805 41b9b02edd246f00118ab1cb32e1a8c3 477 Gene3D G3DSA:1.10.287.130 258 322 2.7E-6 T 29-03-2018 GBCGDNIH2_RS03805 41b9b02edd246f00118ab1cb32e1a8c3 477 Pfam PF00672 HAMP domain 215 264 9.3E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 GBCGDNIH2_RS03805 41b9b02edd246f00118ab1cb32e1a8c3 477 Gene3D G3DSA:3.30.565.10 331 477 2.3E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS03805 41b9b02edd246f00118ab1cb32e1a8c3 477 SMART SM00304 215 267 4.2E-6 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 GBCGDNIH2_RS03805 41b9b02edd246f00118ab1cb32e1a8c3 477 SMART SM00387 369 477 1.4E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS03060 22cb4c6e884bf7e3300f1ca3e6119657 166 Pfam PF06676 Protein of unknown function (DUF1178) 1 162 2.1E-50 T 29-03-2018 IPR009562 Protein of unknown function DUF1178 GBCGDNIH2_RS03060 22cb4c6e884bf7e3300f1ca3e6119657 166 PIRSF PIRSF032131 1 166 1.4E-40 T 29-03-2018 IPR009562 Protein of unknown function DUF1178 GBCGDNIH2_RS07355 bfc12b9c22eee3eaa7b5bbb6203d9747 354 TIGRFAM TIGR01869 casC_Cse4: CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI 3 322 2.1E-91 T 29-03-2018 IPR010148 CRISPR-associated protein, CT1975 GBCGDNIH2_RS07355 bfc12b9c22eee3eaa7b5bbb6203d9747 354 Pfam PF09344 CT1975-like protein 5 327 6.7E-101 T 29-03-2018 IPR010148 CRISPR-associated protein, CT1975 GBCGDNIH2_RS01695 01f048850f2a21399772bdc1a8a8c288 309 SUPERFAMILY SSF53756 3 303 6.38E-55 T 29-03-2018 GBCGDNIH2_RS01695 01f048850f2a21399772bdc1a8a8c288 309 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 160 286 2.8E-18 T 29-03-2018 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 GBCGDNIH2_RS01695 01f048850f2a21399772bdc1a8a8c288 309 Gene3D G3DSA:3.40.50.2000 153 306 3.5E-26 T 29-03-2018 GBCGDNIH2_RS01695 01f048850f2a21399772bdc1a8a8c288 309 Gene3D G3DSA:3.40.50.2000 2 149 3.6E-24 T 29-03-2018 GBCGDNIH2_RS09550 dd7f7c53a1d8b275b3bd9356f0fdcc06 632 SUPERFAMILY SSF101790 544 631 4.41E-16 T 29-03-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain GBCGDNIH2_RS09550 dd7f7c53a1d8b275b3bd9356f0fdcc06 632 Gene3D G3DSA:3.30.1360.120 254 385 4.7E-23 T 29-03-2018 GBCGDNIH2_RS09550 dd7f7c53a1d8b275b3bd9356f0fdcc06 632 Gene3D G3DSA:2.40.30.110 541 632 1.2E-17 T 29-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 GBCGDNIH2_RS09550 dd7f7c53a1d8b275b3bd9356f0fdcc06 632 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 527 606 9.6E-13 T 29-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 GBCGDNIH2_RS09550 dd7f7c53a1d8b275b3bd9356f0fdcc06 632 Gene3D G3DSA:4.10.1250.10 497 538 6.6E-8 T 29-03-2018 GBCGDNIH2_RS09550 dd7f7c53a1d8b275b3bd9356f0fdcc06 632 SUPERFAMILY SSF103025 254 536 7.38E-81 T 29-03-2018 GBCGDNIH2_RS09550 dd7f7c53a1d8b275b3bd9356f0fdcc06 632 Gene3D G3DSA:3.30.1360.120 386 496 1.5E-21 T 29-03-2018 GBCGDNIH2_RS09550 dd7f7c53a1d8b275b3bd9356f0fdcc06 632 Pfam PF09347 Domain of unknown function (DUF1989) 37 205 8.5E-47 T 29-03-2018 IPR018959 Domain of unknown function DUF1989 GBCGDNIH2_RS09550 dd7f7c53a1d8b275b3bd9356f0fdcc06 632 Pfam PF01571 Aminomethyltransferase folate-binding domain 260 519 4.5E-73 T 29-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal GBCGDNIH2_RS03030 b64299fd316fcda5c9283c6b761d6bf5 332 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 1 332 39.56 T 29-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 GBCGDNIH2_RS03030 b64299fd316fcda5c9283c6b761d6bf5 332 SUPERFAMILY SSF102114 2 277 8.89E-78 T 29-03-2018 GBCGDNIH2_RS03030 b64299fd316fcda5c9283c6b761d6bf5 332 Pfam PF04055 Radical SAM superfamily 14 179 1.1E-28 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 GBCGDNIH2_RS03030 b64299fd316fcda5c9283c6b761d6bf5 332 Pfam PF13353 4Fe-4S single cluster domain 17 111 8.1E-8 T 29-03-2018 GBCGDNIH2_RS03030 b64299fd316fcda5c9283c6b761d6bf5 332 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 16 27 - T 29-03-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 Reactome: R-HSA-947581 GBCGDNIH2_RS03030 b64299fd316fcda5c9283c6b761d6bf5 332 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 1 332 4.7E-112 T 29-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 GBCGDNIH2_RS03030 b64299fd316fcda5c9283c6b761d6bf5 332 Gene3D G3DSA:3.20.20.70 1 332 2.3E-80 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS03030 b64299fd316fcda5c9283c6b761d6bf5 332 SMART SM00729 10 220 1.6E-9 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 GBCGDNIH2_RS03030 b64299fd316fcda5c9283c6b761d6bf5 332 Pfam PF06463 Molybdenum Cofactor Synthesis C 186 311 6.9E-41 T 29-03-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 Reactome: R-HSA-947581 GBCGDNIH2_RS11280 c73dbea9f3334aedf9912e3c70e95dd9 699 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 8 696 0.0 T 29-03-2018 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 GBCGDNIH2_RS11280 c73dbea9f3334aedf9912e3c70e95dd9 699 SUPERFAMILY SSF51445 501 578 5.76E-135 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily GBCGDNIH2_RS11280 c73dbea9f3334aedf9912e3c70e95dd9 699 SUPERFAMILY SSF51445 142 472 5.76E-135 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily GBCGDNIH2_RS11280 c73dbea9f3334aedf9912e3c70e95dd9 699 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 12 100 1.0E-19 T 29-03-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077 GBCGDNIH2_RS11280 c73dbea9f3334aedf9912e3c70e95dd9 699 SUPERFAMILY SSF51011 589 696 4.14E-25 T 29-03-2018 GBCGDNIH2_RS11280 c73dbea9f3334aedf9912e3c70e95dd9 699 SUPERFAMILY SSF81296 8 154 3.36E-49 T 29-03-2018 IPR014756 Immunoglobulin E-set GBCGDNIH2_RS11280 c73dbea9f3334aedf9912e3c70e95dd9 699 Gene3D G3DSA:2.60.40.10 8 143 1.4E-45 T 29-03-2018 IPR013783 Immunoglobulin-like fold GBCGDNIH2_RS11280 c73dbea9f3334aedf9912e3c70e95dd9 699 Gene3D G3DSA:3.20.20.80 144 581 1.7E-115 T 29-03-2018 GBCGDNIH2_RS11280 c73dbea9f3334aedf9912e3c70e95dd9 699 Gene3D G3DSA:2.60.40.1180 582 698 3.5E-28 T 29-03-2018 GBCGDNIH2_RS11280 c73dbea9f3334aedf9912e3c70e95dd9 699 SMART SM00642 140 569 1.1E-8 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 GBCGDNIH2_RS11280 c73dbea9f3334aedf9912e3c70e95dd9 699 Pfam PF00128 Alpha amylase, catalytic domain 193 280 6.6E-9 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 GBCGDNIH2_RS01160 4f2480cb7ccf971b0742d744ad0ea33b 532 SUPERFAMILY SSF56954 14 480 4.45E-93 T 29-03-2018 GBCGDNIH2_RS01160 4f2480cb7ccf971b0742d744ad0ea33b 532 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 27 477 1.6E-93 T 29-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 GBCGDNIH2_RS01160 4f2480cb7ccf971b0742d744ad0ea33b 532 Gene3D G3DSA:1.20.1600.10 31 483 1.8E-89 T 29-03-2018 GBCGDNIH2_RS01160 4f2480cb7ccf971b0742d744ad0ea33b 532 Pfam PF02321 Outer membrane efflux protein 77 268 1.6E-16 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 GBCGDNIH2_RS01160 4f2480cb7ccf971b0742d744ad0ea33b 532 Pfam PF02321 Outer membrane efflux protein 297 474 1.0E-19 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 GBCGDNIH2_RS11515 10ac91d98ad470006114ce4e70ddd200 571 Pfam PF13524 Glycosyl transferases group 1 465 534 3.1E-10 T 29-03-2018 GBCGDNIH2_RS11515 10ac91d98ad470006114ce4e70ddd200 571 Gene3D G3DSA:3.40.50.150 18 221 4.7E-27 T 29-03-2018 GBCGDNIH2_RS11515 10ac91d98ad470006114ce4e70ddd200 571 Pfam PF13489 Methyltransferase domain 30 179 5.7E-15 T 29-03-2018 GBCGDNIH2_RS11515 10ac91d98ad470006114ce4e70ddd200 571 Gene3D G3DSA:3.40.50.2000 361 533 5.2E-11 T 29-03-2018 GBCGDNIH2_RS11515 10ac91d98ad470006114ce4e70ddd200 571 SUPERFAMILY SSF53756 300 538 4.87E-7 T 29-03-2018 GBCGDNIH2_RS11515 10ac91d98ad470006114ce4e70ddd200 571 SUPERFAMILY SSF53335 20 186 2.91E-29 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GBCGDNIH2_RS04650 76c49ace00952ff5dd706618173b7646 375 SUPERFAMILY SSF56349 60 358 7.3E-34 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 GBCGDNIH2_RS04650 76c49ace00952ff5dd706618173b7646 375 Gene3D G3DSA:1.10.150.130 54 158 3.2E-9 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal GBCGDNIH2_RS04650 76c49ace00952ff5dd706618173b7646 375 Pfam PF00589 Phage integrase family 160 351 1.5E-13 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 GBCGDNIH2_RS04650 76c49ace00952ff5dd706618173b7646 375 Gene3D G3DSA:1.10.443.10 159 366 9.3E-27 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 GBCGDNIH2_RS09190 82a47ec74423990617aaf85d97b8f508 572 Gene3D G3DSA:1.50.10.100 93 312 1.9E-11 T 29-03-2018 GBCGDNIH2_RS09190 82a47ec74423990617aaf85d97b8f508 572 Pfam PF07940 Heparinase II/III-like protein 298 565 8.0E-68 T 29-03-2018 IPR012480 Heparinase II/III-like GO:0016829 GBCGDNIH2_RS04600 e7aded60ea3b089b82fa7c69318c1c41 225 SUPERFAMILY SSF50199 84 223 7.32E-19 T 29-03-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold GBCGDNIH2_RS04600 e7aded60ea3b089b82fa7c69318c1c41 225 SMART SM00318 76 220 3.4E-4 T 29-03-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold GBCGDNIH2_RS04600 e7aded60ea3b089b82fa7c69318c1c41 225 Pfam PF00565 Staphylococcal nuclease homologue 98 219 5.2E-6 T 29-03-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold GBCGDNIH2_RS04600 e7aded60ea3b089b82fa7c69318c1c41 225 Gene3D G3DSA:2.40.50.90 78 225 2.0E-22 T 29-03-2018 IPR035437 Staphylococcal nuclease (SNase-like), OB-fold/extended TUDOR domain GBCGDNIH2_RS02195 e93a4afd39cbff41e6c78e1d16c2cd8f 305 Gene3D G3DSA:3.30.1490.20 98 164 3.6E-14 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 GBCGDNIH2_RS02195 e93a4afd39cbff41e6c78e1d16c2cd8f 305 Gene3D G3DSA:3.40.50.20 1 97 4.8E-34 T 29-03-2018 GBCGDNIH2_RS02195 e93a4afd39cbff41e6c78e1d16c2cd8f 305 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 2 302 32.964 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GBCGDNIH2_RS02195 e93a4afd39cbff41e6c78e1d16c2cd8f 305 PIRSF PIRSF039102 44 305 7.4E-65 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GBCGDNIH2_RS02195 e93a4afd39cbff41e6c78e1d16c2cd8f 305 PIRSF PIRSF039102 1 51 5.3E-10 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GBCGDNIH2_RS02195 e93a4afd39cbff41e6c78e1d16c2cd8f 305 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 3 301 1.4E-78 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GBCGDNIH2_RS02195 e93a4afd39cbff41e6c78e1d16c2cd8f 305 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 64 75 - T 29-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GBCGDNIH2_RS02195 e93a4afd39cbff41e6c78e1d16c2cd8f 305 Pfam PF01820 D-ala D-ala ligase N-terminus 3 85 2.6E-20 T 29-03-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GBCGDNIH2_RS02195 e93a4afd39cbff41e6c78e1d16c2cd8f 305 Gene3D G3DSA:3.30.470.20 165 303 9.6E-35 T 29-03-2018 GBCGDNIH2_RS02195 e93a4afd39cbff41e6c78e1d16c2cd8f 305 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 240 272 - T 29-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GBCGDNIH2_RS02195 e93a4afd39cbff41e6c78e1d16c2cd8f 305 SUPERFAMILY SSF52440 3 97 1.82E-29 T 29-03-2018 IPR016185 Pre-ATP-grasp domain GBCGDNIH2_RS02195 e93a4afd39cbff41e6c78e1d16c2cd8f 305 SUPERFAMILY SSF56059 97 299 8.75E-47 T 29-03-2018 GBCGDNIH2_RS02195 e93a4afd39cbff41e6c78e1d16c2cd8f 305 Pfam PF07478 D-ala D-ala ligase C-terminus 128 298 2.3E-37 T 29-03-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GBCGDNIH2_RS01365 389d5940177c9f63b525b41e6efbc85c 194 TIGRFAM TIGR00385 dsbE: periplasmic protein thiol:disulfide oxidoreductases, DsbE subfamily 20 190 1.7E-45 T 29-03-2018 IPR004799 Periplasmic protein thiol:disulphide oxidoreductase DsbE GO:0015036|GO:0017004|GO:0030288 GBCGDNIH2_RS01365 389d5940177c9f63b525b41e6efbc85c 194 Gene3D G3DSA:3.40.30.10 51 194 1.5E-25 T 29-03-2018 GBCGDNIH2_RS01365 389d5940177c9f63b525b41e6efbc85c 194 SUPERFAMILY SSF52833 62 192 3.44E-32 T 29-03-2018 IPR012336 Thioredoxin-like fold GBCGDNIH2_RS01365 389d5940177c9f63b525b41e6efbc85c 194 ProSitePatterns PS00194 Thioredoxin family active site. 86 104 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 GBCGDNIH2_RS01365 389d5940177c9f63b525b41e6efbc85c 194 Pfam PF00578 AhpC/TSA family 54 171 2.3E-12 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 GBCGDNIH2_RS11435 5376463c6dc0ac49b8656c5b598a2056 154 Gene3D G3DSA:3.40.630.30 12 152 7.3E-14 T 29-03-2018 GBCGDNIH2_RS11435 5376463c6dc0ac49b8656c5b598a2056 154 SUPERFAMILY SSF55729 38 144 1.06E-14 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase GBCGDNIH2_RS11435 5376463c6dc0ac49b8656c5b598a2056 154 Pfam PF00583 Acetyltransferase (GNAT) family 72 134 7.8E-6 T 29-03-2018 IPR000182 GNAT domain GO:0008080 GBCGDNIH2_RS11310 19f8e22bf51a5233fdd3c3f8175e3725 67 SMART SM00357 3 67 2.1E-27 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 GBCGDNIH2_RS11310 19f8e22bf51a5233fdd3c3f8175e3725 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 2.5E-25 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 GBCGDNIH2_RS11310 19f8e22bf51a5233fdd3c3f8175e3725 67 PIRSF PIRSF002599 1 67 7.8E-23 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 GBCGDNIH2_RS11310 19f8e22bf51a5233fdd3c3f8175e3725 67 SUPERFAMILY SSF50249 1 66 4.07E-22 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold GBCGDNIH2_RS11310 19f8e22bf51a5233fdd3c3f8175e3725 67 Gene3D G3DSA:2.40.50.140 1 67 9.3E-24 T 29-03-2018 GBCGDNIH2_RS11310 19f8e22bf51a5233fdd3c3f8175e3725 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 29-03-2018 IPR019844 Cold-shock conserved site GBCGDNIH2_RS11310 19f8e22bf51a5233fdd3c3f8175e3725 67 PRINTS PR00050 Cold shock protein signature 25 34 3.4E-12 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 GBCGDNIH2_RS11310 19f8e22bf51a5233fdd3c3f8175e3725 67 PRINTS PR00050 Cold shock protein signature 40 58 3.4E-12 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 GBCGDNIH2_RS11310 19f8e22bf51a5233fdd3c3f8175e3725 67 PRINTS PR00050 Cold shock protein signature 4 19 3.4E-12 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 GBCGDNIH2_RS03720 88d678acb291d981af3c28053f6db298 223 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 38 222 25.754 T 29-03-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 GBCGDNIH2_RS03720 88d678acb291d981af3c28053f6db298 223 Pfam PF01926 50S ribosome-binding GTPase 52 170 4.3E-20 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 GBCGDNIH2_RS03720 88d678acb291d981af3c28053f6db298 223 Gene3D G3DSA:3.40.50.300 34 222 1.0E-29 T 29-03-2018 GBCGDNIH2_RS03720 88d678acb291d981af3c28053f6db298 223 SUPERFAMILY SSF52540 39 220 1.08E-33 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS03720 88d678acb291d981af3c28053f6db298 223 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 34 218 3.7E-63 T 29-03-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 GBCGDNIH2_RS07460 d50d8640df47be0a7b6bfab47b615115 616 Pfam PF01368 DHH family 115 207 1.8E-6 T 29-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 GBCGDNIH2_RS07460 d50d8640df47be0a7b6bfab47b615115 616 SUPERFAMILY SSF64182 89 484 4.97E-104 T 29-03-2018 GBCGDNIH2_RS07460 d50d8640df47be0a7b6bfab47b615115 616 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 60 612 1.3E-140 T 29-03-2018 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 GBCGDNIH2_RS07460 d50d8640df47be0a7b6bfab47b615115 616 Pfam PF02272 DHHA1 domain 369 482 3.8E-16 T 29-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 GBCGDNIH2_RS07460 d50d8640df47be0a7b6bfab47b615115 616 Gene3D G3DSA:3.90.1640.10 94 283 1.1E-19 T 29-03-2018 GBCGDNIH2_RS04135 9f57d0050799862aac9ac852ddec9945 898 Pfam PF13368 Topoisomerase C-terminal repeat 724 773 1.3E-18 T 29-03-2018 IPR025589 Topoisomerase C-terminal repeat GBCGDNIH2_RS04135 9f57d0050799862aac9ac852ddec9945 898 Pfam PF13368 Topoisomerase C-terminal repeat 661 719 9.2E-14 T 29-03-2018 IPR025589 Topoisomerase C-terminal repeat GBCGDNIH2_RS04135 9f57d0050799862aac9ac852ddec9945 898 Pfam PF13368 Topoisomerase C-terminal repeat 782 832 4.1E-17 T 29-03-2018 IPR025589 Topoisomerase C-terminal repeat GBCGDNIH2_RS04135 9f57d0050799862aac9ac852ddec9945 898 SMART SM00437 249 522 2.9E-109 T 29-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 GBCGDNIH2_RS04135 9f57d0050799862aac9ac852ddec9945 898 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 604 639 5.5E-12 T 29-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 GBCGDNIH2_RS04135 9f57d0050799862aac9ac852ddec9945 898 Gene3D G3DSA:3.30.65.10 595 647 1.4E-10 T 29-03-2018 GBCGDNIH2_RS04135 9f57d0050799862aac9ac852ddec9945 898 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 5 638 8.5E-231 T 29-03-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 GBCGDNIH2_RS04135 9f57d0050799862aac9ac852ddec9945 898 Gene3D G3DSA:3.40.50.140 1 132 6.3E-40 T 29-03-2018 GBCGDNIH2_RS04135 9f57d0050799862aac9ac852ddec9945 898 SMART SM00436 107 195 1.4E-42 T 29-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 GBCGDNIH2_RS04135 9f57d0050799862aac9ac852ddec9945 898 SUPERFAMILY SSF56712 604 613 1.11E-181 T 29-03-2018 IPR023405 DNA topoisomerase, type IA, core domain GBCGDNIH2_RS04135 9f57d0050799862aac9ac852ddec9945 898 SUPERFAMILY SSF56712 2 573 1.11E-181 T 29-03-2018 IPR023405 DNA topoisomerase, type IA, core domain GBCGDNIH2_RS04135 9f57d0050799862aac9ac852ddec9945 898 SMART SM00493 2 102 5.5E-24 T 29-03-2018 IPR006171 TOPRIM domain GBCGDNIH2_RS04135 9f57d0050799862aac9ac852ddec9945 898 Gene3D G3DSA:2.70.20.10 331 463 1.4E-40 T 29-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 GBCGDNIH2_RS04135 9f57d0050799862aac9ac852ddec9945 898 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 76 89 2.7E-34 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 GBCGDNIH2_RS04135 9f57d0050799862aac9ac852ddec9945 898 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 377 393 2.7E-34 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 GBCGDNIH2_RS04135 9f57d0050799862aac9ac852ddec9945 898 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 299 308 2.7E-34 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 GBCGDNIH2_RS04135 9f57d0050799862aac9ac852ddec9945 898 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 485 499 2.7E-34 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 GBCGDNIH2_RS04135 9f57d0050799862aac9ac852ddec9945 898 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 165 183 2.7E-34 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 GBCGDNIH2_RS04135 9f57d0050799862aac9ac852ddec9945 898 Gene3D G3DSA:1.10.460.10 138 328 4.8E-38 T 29-03-2018 GBCGDNIH2_RS04135 9f57d0050799862aac9ac852ddec9945 898 Gene3D G3DSA:1.10.460.10 464 579 1.6E-27 T 29-03-2018 GBCGDNIH2_RS04135 9f57d0050799862aac9ac852ddec9945 898 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 286 308 - T 29-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 GBCGDNIH2_RS04135 9f57d0050799862aac9ac852ddec9945 898 Pfam PF01131 DNA topoisomerase 131 560 5.8E-121 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 GBCGDNIH2_RS04135 9f57d0050799862aac9ac852ddec9945 898 Pfam PF01751 Toprim domain 4 116 4.6E-24 T 29-03-2018 IPR006171 TOPRIM domain GBCGDNIH2_RS04135 9f57d0050799862aac9ac852ddec9945 898 Hamap MF_00952 DNA topoisomerase 1 [topA]. 2 736 51.305 T 29-03-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 GBCGDNIH2_RS04135 9f57d0050799862aac9ac852ddec9945 898 SUPERFAMILY SSF57783 603 640 7.31E-8 T 29-03-2018 GBCGDNIH2_RS00390 cdf17b15cf6750c0b598a8846794a2ad 341 SUPERFAMILY SSF46689 265 314 3.58E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 GBCGDNIH2_RS00390 cdf17b15cf6750c0b598a8846794a2ad 341 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 266 308 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 GBCGDNIH2_RS00390 cdf17b15cf6750c0b598a8846794a2ad 341 SUPERFAMILY SSF52317 2 192 1.03E-37 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like GBCGDNIH2_RS00390 cdf17b15cf6750c0b598a8846794a2ad 341 Gene3D G3DSA:3.40.50.880 1 221 1.1E-33 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like GBCGDNIH2_RS00390 cdf17b15cf6750c0b598a8846794a2ad 341 Gene3D G3DSA:1.10.10.60 267 320 8.2E-12 T 29-03-2018 GBCGDNIH2_RS00390 cdf17b15cf6750c0b598a8846794a2ad 341 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 296 312 4.5E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 GBCGDNIH2_RS00390 cdf17b15cf6750c0b598a8846794a2ad 341 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 281 296 4.5E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 GBCGDNIH2_RS00390 cdf17b15cf6750c0b598a8846794a2ad 341 Pfam PF01965 DJ-1/PfpI family 42 174 4.5E-9 T 29-03-2018 IPR002818 DJ-1/PfpI GBCGDNIH2_RS00390 cdf17b15cf6750c0b598a8846794a2ad 341 Pfam PF12833 Helix-turn-helix domain 235 313 2.1E-21 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 GBCGDNIH2_RS00390 cdf17b15cf6750c0b598a8846794a2ad 341 Gene3D G3DSA:1.10.10.60 222 266 1.4E-8 T 29-03-2018 GBCGDNIH2_RS00390 cdf17b15cf6750c0b598a8846794a2ad 341 SMART SM00342 229 312 5.7E-24 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 GBCGDNIH2_RS00390 cdf17b15cf6750c0b598a8846794a2ad 341 SUPERFAMILY SSF46689 212 260 1.16E-5 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 GBCGDNIH2_RS02545 5949874e146194bdaebcfa527580bc15 261 Gene3D G3DSA:3.40.50.300 40 250 2.0E-39 T 29-03-2018 GBCGDNIH2_RS02545 5949874e146194bdaebcfa527580bc15 261 Pfam PF13500 AAA domain 43 219 7.0E-31 T 29-03-2018 GBCGDNIH2_RS02545 5949874e146194bdaebcfa527580bc15 261 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 40 248 24.131 T 29-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 GBCGDNIH2_RS02545 5949874e146194bdaebcfa527580bc15 261 PIRSF PIRSF006755 39 259 2.5E-41 T 29-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 GBCGDNIH2_RS02545 5949874e146194bdaebcfa527580bc15 261 SUPERFAMILY SSF52540 43 235 1.14E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS02545 5949874e146194bdaebcfa527580bc15 261 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 44 212 1.6E-37 T 29-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 GBCGDNIH2_RS01110 a8ab3f97577cfc03bc2a1f70361a181a 88 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 20 75 2.6E-21 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 GBCGDNIH2_RS01110 a8ab3f97577cfc03bc2a1f70361a181a 88 SUPERFAMILY SSF116842 14 81 1.83E-19 T 29-03-2018 GBCGDNIH2_RS01110 a8ab3f97577cfc03bc2a1f70361a181a 88 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 20 60 1.0E-12 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 GBCGDNIH2_RS01110 a8ab3f97577cfc03bc2a1f70361a181a 88 Gene3D G3DSA:1.10.287.1040 18 85 1.0E-21 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 GBCGDNIH2_RS01110 a8ab3f97577cfc03bc2a1f70361a181a 88 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 20 80 14.856 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 GBCGDNIH2_RS01110 a8ab3f97577cfc03bc2a1f70361a181a 88 PIRSF PIRSF006488 8 85 2.8E-21 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 GBCGDNIH2_RS01110 a8ab3f97577cfc03bc2a1f70361a181a 88 Pfam PF02609 Exonuclease VII small subunit 21 70 7.1E-18 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 GBCGDNIH2_RS02550 7d5eb63e240fa0aa09f46667c90526de 344 Pfam PF01545 Cation efflux family 45 233 2.1E-43 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 GBCGDNIH2_RS02550 7d5eb63e240fa0aa09f46667c90526de 344 Gene3D G3DSA:1.20.1510.10 37 233 2.4E-56 T 29-03-2018 GBCGDNIH2_RS02550 7d5eb63e240fa0aa09f46667c90526de 344 SUPERFAMILY SSF161111 39 234 1.27E-53 T 29-03-2018 GBCGDNIH2_RS02550 7d5eb63e240fa0aa09f46667c90526de 344 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 39 316 4.5E-81 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 GBCGDNIH2_RS02550 7d5eb63e240fa0aa09f46667c90526de 344 Gene3D G3DSA:3.30.70.1350 236 317 3.2E-13 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain GBCGDNIH2_RS02550 7d5eb63e240fa0aa09f46667c90526de 344 SUPERFAMILY SSF160240 242 315 4.58E-9 T 29-03-2018 GBCGDNIH2_RS03475 925af70e2f5d8bae4b16f17a856c0ef5 336 SUPERFAMILY SSF53850 258 330 1.66E-9 T 29-03-2018 GBCGDNIH2_RS03475 925af70e2f5d8bae4b16f17a856c0ef5 336 SUPERFAMILY SSF53850 94 214 3.1E-25 T 29-03-2018 GBCGDNIH2_RS03475 925af70e2f5d8bae4b16f17a856c0ef5 336 SUPERFAMILY SSF46785 5 115 1.2E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS03475 925af70e2f5d8bae4b16f17a856c0ef5 336 Gene3D G3DSA:3.40.190.10 93 182 2.3E-24 T 29-03-2018 GBCGDNIH2_RS03475 925af70e2f5d8bae4b16f17a856c0ef5 336 Pfam PF03466 LysR substrate binding domain 93 214 7.3E-30 T 29-03-2018 IPR005119 LysR, substrate-binding GBCGDNIH2_RS03475 925af70e2f5d8bae4b16f17a856c0ef5 336 Pfam PF03466 LysR substrate binding domain 258 333 1.3E-10 T 29-03-2018 IPR005119 LysR, substrate-binding GBCGDNIH2_RS03475 925af70e2f5d8bae4b16f17a856c0ef5 336 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 4.4E-14 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS03475 925af70e2f5d8bae4b16f17a856c0ef5 336 Gene3D G3DSA:3.40.190.10 183 308 5.6E-23 T 29-03-2018 GBCGDNIH2_RS03475 925af70e2f5d8bae4b16f17a856c0ef5 336 Gene3D G3DSA:1.10.10.10 3 88 1.9E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS10115 36a4312ebe107f56da2727d52d32dfdc 618 Pfam PF00920 Dehydratase family 34 607 3.7E-218 T 29-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 GBCGDNIH2_RS10115 36a4312ebe107f56da2727d52d32dfdc 618 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 610 4.7E-246 T 29-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 GBCGDNIH2_RS10115 36a4312ebe107f56da2727d52d32dfdc 618 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 122 132 - T 29-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 GBCGDNIH2_RS10115 36a4312ebe107f56da2727d52d32dfdc 618 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 509 520 - T 29-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 GBCGDNIH2_RS10115 36a4312ebe107f56da2727d52d32dfdc 618 SUPERFAMILY SSF143975 3 420 2.75E-135 T 29-03-2018 GBCGDNIH2_RS10115 36a4312ebe107f56da2727d52d32dfdc 618 SUPERFAMILY SSF52016 421 613 4.08E-57 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel GBCGDNIH2_RS10115 36a4312ebe107f56da2727d52d32dfdc 618 Gene3D G3DSA:3.40.50.2300 90 246 8.3E-4 T 29-03-2018 GBCGDNIH2_RS10115 36a4312ebe107f56da2727d52d32dfdc 618 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 610 44.794 T 29-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 GBCGDNIH2_RS09740 afddd21c42fd00a073d70fb4041c5d8b 415 Pfam PF14815 NUDIX domain 267 376 6.1E-19 T 29-03-2018 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 GBCGDNIH2_RS09740 afddd21c42fd00a073d70fb4041c5d8b 415 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 67 183 4.0E-17 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 GBCGDNIH2_RS09740 afddd21c42fd00a073d70fb4041c5d8b 415 SMART SM00478 70 221 5.1E-38 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 GBCGDNIH2_RS09740 afddd21c42fd00a073d70fb4041c5d8b 415 Gene3D G3DSA:1.10.340.30 48 146 2.3E-29 T 29-03-2018 GBCGDNIH2_RS09740 afddd21c42fd00a073d70fb4041c5d8b 415 Gene3D G3DSA:1.10.1670.10 147 256 6.8E-29 T 29-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 GBCGDNIH2_RS09740 afddd21c42fd00a073d70fb4041c5d8b 415 SUPERFAMILY SSF48150 36 253 5.81E-63 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 GBCGDNIH2_RS09740 afddd21c42fd00a073d70fb4041c5d8b 415 SUPERFAMILY SSF55811 251 374 1.31E-19 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 GBCGDNIH2_RS09740 afddd21c42fd00a073d70fb4041c5d8b 415 Gene3D G3DSA:3.90.79.10 257 377 2.3E-8 T 29-03-2018 GBCGDNIH2_RS02445 57a9aed0a7c7e2b680050d8134357fde 84 TIGRFAM TIGR01215 minE: cell division topological specificity factor MinE 2 80 1.1E-19 T 29-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 GBCGDNIH2_RS02445 57a9aed0a7c7e2b680050d8134357fde 84 SUPERFAMILY SSF55229 33 80 1.83E-11 T 29-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 GBCGDNIH2_RS02445 57a9aed0a7c7e2b680050d8134357fde 84 Pfam PF03776 Septum formation topological specificity factor MinE 12 79 2.9E-20 T 29-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 GBCGDNIH2_RS02445 57a9aed0a7c7e2b680050d8134357fde 84 Gene3D G3DSA:3.30.1070.10 1 80 8.4E-21 T 29-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 GBCGDNIH2_RS02445 57a9aed0a7c7e2b680050d8134357fde 84 Hamap MF_00262 Cell division topological specificity factor [minE]. 3 83 15.192 T 29-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 GBCGDNIH2_RS02845 e85dcf8b83703416ce507f727ed0356f 98 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 7 96 21.223 T 29-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 GBCGDNIH2_RS02845 e85dcf8b83703416ce507f727ed0356f 98 SUPERFAMILY SSF54189 6 95 3.35E-31 T 29-03-2018 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS02845 e85dcf8b83703416ce507f727ed0356f 98 Pfam PF00276 Ribosomal protein L23 8 92 2.5E-30 T 29-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 GBCGDNIH2_RS02845 e85dcf8b83703416ce507f727ed0356f 98 Gene3D G3DSA:3.30.70.330 5 98 3.2E-32 T 29-03-2018 GBCGDNIH2_RS11495 fd3b9eae01bd6f33d8b087d85fab3948 360 SMART SM01005 232 356 4.8E-59 T 29-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 GBCGDNIH2_RS11495 fd3b9eae01bd6f33d8b087d85fab3948 360 SUPERFAMILY SSF50621 225 356 2.02E-43 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 GBCGDNIH2_RS11495 fd3b9eae01bd6f33d8b087d85fab3948 360 Gene3D G3DSA:3.20.20.10 1 217 1.2E-39 T 29-03-2018 IPR029066 PLP-binding barrel GBCGDNIH2_RS11495 fd3b9eae01bd6f33d8b087d85fab3948 360 Pfam PF01168 Alanine racemase, N-terminal domain 6 221 8.8E-52 T 29-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 GBCGDNIH2_RS11495 fd3b9eae01bd6f33d8b087d85fab3948 360 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 30 40 - T 29-03-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 GBCGDNIH2_RS11495 fd3b9eae01bd6f33d8b087d85fab3948 360 Hamap MF_01201 Alanine racemase. 1 356 27.156 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 GBCGDNIH2_RS11495 fd3b9eae01bd6f33d8b087d85fab3948 360 SUPERFAMILY SSF51419 6 233 4.71E-56 T 29-03-2018 IPR029066 PLP-binding barrel GBCGDNIH2_RS11495 fd3b9eae01bd6f33d8b087d85fab3948 360 PRINTS PR00992 Alanine racemase signature 61 79 6.9E-44 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 GBCGDNIH2_RS11495 fd3b9eae01bd6f33d8b087d85fab3948 360 PRINTS PR00992 Alanine racemase signature 122 134 6.9E-44 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 GBCGDNIH2_RS11495 fd3b9eae01bd6f33d8b087d85fab3948 360 PRINTS PR00992 Alanine racemase signature 156 167 6.9E-44 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 GBCGDNIH2_RS11495 fd3b9eae01bd6f33d8b087d85fab3948 360 PRINTS PR00992 Alanine racemase signature 194 221 6.9E-44 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 GBCGDNIH2_RS11495 fd3b9eae01bd6f33d8b087d85fab3948 360 PRINTS PR00992 Alanine racemase signature 286 303 6.9E-44 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 GBCGDNIH2_RS11495 fd3b9eae01bd6f33d8b087d85fab3948 360 PRINTS PR00992 Alanine racemase signature 25 41 6.9E-44 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 GBCGDNIH2_RS11495 fd3b9eae01bd6f33d8b087d85fab3948 360 PRINTS PR00992 Alanine racemase signature 248 263 6.9E-44 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 GBCGDNIH2_RS11495 fd3b9eae01bd6f33d8b087d85fab3948 360 PRINTS PR00992 Alanine racemase signature 265 280 6.9E-44 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 GBCGDNIH2_RS11495 fd3b9eae01bd6f33d8b087d85fab3948 360 PRINTS PR00992 Alanine racemase signature 338 351 6.9E-44 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 GBCGDNIH2_RS11495 fd3b9eae01bd6f33d8b087d85fab3948 360 Gene3D G3DSA:2.40.37.10 218 358 1.0E-48 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 GBCGDNIH2_RS11495 fd3b9eae01bd6f33d8b087d85fab3948 360 Pfam PF00842 Alanine racemase, C-terminal domain 232 355 1.0E-36 T 29-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 GBCGDNIH2_RS11495 fd3b9eae01bd6f33d8b087d85fab3948 360 TIGRFAM TIGR00492 alr: alanine racemase 4 355 6.2E-73 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 GBCGDNIH2_RS01510 63bc11b60290f90747897c12ceadc008 199 SUPERFAMILY SSF52218 1 197 1.97E-60 T 29-03-2018 IPR029039 Flavoprotein-like domain GBCGDNIH2_RS01510 63bc11b60290f90747897c12ceadc008 199 Hamap MF_01017 NAD(P)H dehydrogenase (quinone). 1 199 42.022 T 29-03-2018 IPR010089 Flavoprotein WrbA-like GO:0003955|GO:0010181 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 GBCGDNIH2_RS01510 63bc11b60290f90747897c12ceadc008 199 Pfam PF03358 NADPH-dependent FMN reductase 3 139 2.7E-9 T 29-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 GBCGDNIH2_RS01510 63bc11b60290f90747897c12ceadc008 199 TIGRFAM TIGR01755 flav_wrbA: NAD(P)H:quinone oxidoreductase, type IV 2 197 4.1E-93 T 29-03-2018 IPR010089 Flavoprotein WrbA-like GO:0003955|GO:0010181 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 GBCGDNIH2_RS01510 63bc11b60290f90747897c12ceadc008 199 Gene3D G3DSA:3.40.50.360 2 199 1.3E-42 T 29-03-2018 IPR029039 Flavoprotein-like domain GBCGDNIH2_RS07950 0510051d2e296f1a0a03dbf39930f5f8 306 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 32 304 58.108 T 29-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 GBCGDNIH2_RS07950 0510051d2e296f1a0a03dbf39930f5f8 306 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 34 302 1.4E-99 T 29-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 GBCGDNIH2_RS07950 0510051d2e296f1a0a03dbf39930f5f8 306 Pfam PF00448 SRP54-type protein, GTPase domain 103 303 2.2E-71 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 GBCGDNIH2_RS07950 0510051d2e296f1a0a03dbf39930f5f8 306 SUPERFAMILY SSF52540 100 300 8.49E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS07950 0510051d2e296f1a0a03dbf39930f5f8 306 SMART SM00963 9 88 1.0E-15 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 GBCGDNIH2_RS07950 0510051d2e296f1a0a03dbf39930f5f8 306 SMART SM00962 103 304 5.3E-109 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 GBCGDNIH2_RS07950 0510051d2e296f1a0a03dbf39930f5f8 306 Pfam PF02881 SRP54-type protein, helical bundle domain 20 83 9.0E-10 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 GBCGDNIH2_RS07950 0510051d2e296f1a0a03dbf39930f5f8 306 Gene3D G3DSA:1.20.120.140 5 93 6.2E-25 T 29-03-2018 GBCGDNIH2_RS07950 0510051d2e296f1a0a03dbf39930f5f8 306 SUPERFAMILY SSF47364 4 81 2.22E-17 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 GBCGDNIH2_RS07950 0510051d2e296f1a0a03dbf39930f5f8 306 Gene3D G3DSA:3.40.50.300 100 305 2.7E-38 T 29-03-2018 GBCGDNIH2_RS07950 0510051d2e296f1a0a03dbf39930f5f8 306 SMART SM00382 102 242 9.6E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS02325 c05889b2aecc762f8c26b0a6b163dfad 201 SUPERFAMILY SSF52833 2 77 4.07E-14 T 29-03-2018 IPR012336 Thioredoxin-like fold GBCGDNIH2_RS02325 c05889b2aecc762f8c26b0a6b163dfad 201 SUPERFAMILY SSF47616 71 199 9.66E-16 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like GBCGDNIH2_RS02325 c05889b2aecc762f8c26b0a6b163dfad 201 Pfam PF13410 Glutathione S-transferase, C-terminal domain 124 185 9.6E-6 T 29-03-2018 GBCGDNIH2_RS02325 c05889b2aecc762f8c26b0a6b163dfad 201 Pfam PF13417 Glutathione S-transferase, N-terminal domain 3 75 7.3E-14 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 GBCGDNIH2_RS02325 c05889b2aecc762f8c26b0a6b163dfad 201 Gene3D G3DSA:3.40.30.10 1 99 1.7E-15 T 29-03-2018 GBCGDNIH2_RS02325 c05889b2aecc762f8c26b0a6b163dfad 201 Gene3D G3DSA:1.20.1050.10 100 201 3.3E-9 T 29-03-2018 GBCGDNIH2_RS11795 7bb05dc1e53d9796a5c6c6d65873e7f8 434 SUPERFAMILY SSF51905 389 423 4.21E-46 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS11795 7bb05dc1e53d9796a5c6c6d65873e7f8 434 SUPERFAMILY SSF51905 3 294 4.21E-46 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS11795 7bb05dc1e53d9796a5c6c6d65873e7f8 434 PRINTS PR00419 Adrenodoxin reductase family signature 3 25 3.1E-7 T 29-03-2018 GBCGDNIH2_RS11795 7bb05dc1e53d9796a5c6c6d65873e7f8 434 PRINTS PR00419 Adrenodoxin reductase family signature 26 39 3.1E-7 T 29-03-2018 GBCGDNIH2_RS11795 7bb05dc1e53d9796a5c6c6d65873e7f8 434 Gene3D G3DSA:3.50.50.60 2 433 1.0E-31 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS11795 7bb05dc1e53d9796a5c6c6d65873e7f8 434 Pfam PF01593 Flavin containing amine oxidoreductase 13 354 8.8E-26 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 GBCGDNIH2_RS10470 542e7a6a3fbc9e62a64dc9fc9afc4c4a 352 Gene3D G3DSA:3.30.200.20 8 98 2.6E-29 T 29-03-2018 GBCGDNIH2_RS10470 542e7a6a3fbc9e62a64dc9fc9afc4c4a 352 Pfam PF01636 Phosphotransferase enzyme family 30 254 4.4E-27 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase GBCGDNIH2_RS10470 542e7a6a3fbc9e62a64dc9fc9afc4c4a 352 Gene3D G3DSA:3.90.1200.10 99 339 5.1E-26 T 29-03-2018 GBCGDNIH2_RS10470 542e7a6a3fbc9e62a64dc9fc9afc4c4a 352 SUPERFAMILY SSF56112 8 321 7.58E-43 T 29-03-2018 IPR011009 Protein kinase-like domain GBCGDNIH2_RS11340 af6b1b886a9ea00b49ecd9148a457996 482 PIRSF PIRSF004919 21 481 1.4E-128 T 29-03-2018 IPR025502 TldD GBCGDNIH2_RS11340 af6b1b886a9ea00b49ecd9148a457996 482 SUPERFAMILY SSF111283 34 480 4.84E-123 T 29-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 GBCGDNIH2_RS11340 af6b1b886a9ea00b49ecd9148a457996 482 Pfam PF01523 Putative modulator of DNA gyrase 42 332 1.6E-62 T 29-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 GBCGDNIH2_RS11340 af6b1b886a9ea00b49ecd9148a457996 482 Gene3D G3DSA:3.30.2290.10 11 235 3.5E-43 T 29-03-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal domain GBCGDNIH2_RS11085 906cac2fb91f6f65bd683287b5d47b18 306 Gene3D G3DSA:2.40.50.100 147 285 8.3E-6 T 29-03-2018 GBCGDNIH2_RS11085 906cac2fb91f6f65bd683287b5d47b18 306 Pfam PF13437 HlyD family secretion protein 154 237 9.3E-9 T 29-03-2018 GBCGDNIH2_RS11085 906cac2fb91f6f65bd683287b5d47b18 306 Gene3D G3DSA:2.40.50.100 46 117 2.7E-19 T 29-03-2018 GBCGDNIH2_RS11085 906cac2fb91f6f65bd683287b5d47b18 306 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 46 237 2.1E-33 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 GBCGDNIH2_RS11085 906cac2fb91f6f65bd683287b5d47b18 306 SUPERFAMILY SSF111369 40 205 4.97E-23 T 29-03-2018 GBCGDNIH2_RS11085 906cac2fb91f6f65bd683287b5d47b18 306 Pfam PF13533 Biotin-lipoyl like 46 93 6.5E-17 T 29-03-2018 GBCGDNIH2_RS03540 d37f0c5c9d6e985536dfb63f0c4ad264 75 Pfam PF06620 Protein of unknown function (DUF1150) 36 75 3.8E-8 T 29-03-2018 IPR009531 Protein of unknown function DUF1150 GBCGDNIH2_RS01775 70a5016b0f7fb1f6bec80263a2d84edd 197 Pfam PF07799 Protein of unknown function (DUF1643) 45 179 1.9E-37 T 29-03-2018 IPR012441 Protein of unknown function DUF1643 GBCGDNIH2_RS03815 2b92fb80acf88d5c1e39e48d683d623a 448 PRINTS PR00313 NodO calcium binding signature 366 375 1.5E-7 T 29-03-2018 GBCGDNIH2_RS03815 2b92fb80acf88d5c1e39e48d683d623a 448 PRINTS PR00313 NodO calcium binding signature 216 227 1.5E-7 T 29-03-2018 GBCGDNIH2_RS03815 2b92fb80acf88d5c1e39e48d683d623a 448 PRINTS PR00313 NodO calcium binding signature 255 263 1.5E-7 T 29-03-2018 GBCGDNIH2_RS03815 2b92fb80acf88d5c1e39e48d683d623a 448 PRINTS PR00313 NodO calcium binding signature 348 356 1.5E-7 T 29-03-2018 GBCGDNIH2_RS03815 2b92fb80acf88d5c1e39e48d683d623a 448 SUPERFAMILY SSF51120 167 291 9.07E-6 T 29-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal GBCGDNIH2_RS03815 2b92fb80acf88d5c1e39e48d683d623a 448 Gene3D G3DSA:2.150.10.10 30 274 0.17 T 29-03-2018 GBCGDNIH2_RS03815 2b92fb80acf88d5c1e39e48d683d623a 448 Gene3D G3DSA:2.150.10.10 275 448 3.0E-14 T 29-03-2018 GBCGDNIH2_RS03815 2b92fb80acf88d5c1e39e48d683d623a 448 SUPERFAMILY SSF51120 249 443 2.41E-16 T 29-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal GBCGDNIH2_RS03440 0a5e4b9e7e91504d269eec3fbafa7de6 281 Gene3D G3DSA:3.90.850.10 51 280 7.8E-78 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 GBCGDNIH2_RS03440 0a5e4b9e7e91504d269eec3fbafa7de6 281 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 73 277 1.7E-64 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 GBCGDNIH2_RS03440 0a5e4b9e7e91504d269eec3fbafa7de6 281 SUPERFAMILY SSF56529 63 278 1.14E-76 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 GBCGDNIH2_RS00845 a14717cd2ebe1981075fe1f33f56f94d 317 SUPERFAMILY SSF53474 16 299 6.27E-52 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS00845 a14717cd2ebe1981075fe1f33f56f94d 317 PIRSF PIRSF006431 1 316 7.7E-121 T 29-03-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 GBCGDNIH2_RS00845 a14717cd2ebe1981075fe1f33f56f94d 317 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 39 47 4.0E-13 T 29-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 GBCGDNIH2_RS00845 a14717cd2ebe1981075fe1f33f56f94d 317 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 65 76 4.0E-13 T 29-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 GBCGDNIH2_RS00845 a14717cd2ebe1981075fe1f33f56f94d 317 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 108 122 4.0E-13 T 29-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 GBCGDNIH2_RS00845 a14717cd2ebe1981075fe1f33f56f94d 317 Gene3D G3DSA:3.40.50.1820 4 315 2.6E-56 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS00845 a14717cd2ebe1981075fe1f33f56f94d 317 Pfam PF00561 alpha/beta hydrolase fold 38 297 9.7E-23 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 GBCGDNIH2_RS00845 a14717cd2ebe1981075fe1f33f56f94d 317 TIGRFAM TIGR01249 pro_imino_pep_1: prolyl aminopeptidase 12 312 1.2E-105 T 29-03-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 GBCGDNIH2_RS03010 7919c5dd48961868177a4bb6da061577 326 Gene3D G3DSA:2.40.70.10 45 260 5.4E-5 T 29-03-2018 IPR021109 Aspartic peptidase domain GBCGDNIH2_RS03010 7919c5dd48961868177a4bb6da061577 326 SUPERFAMILY SSF50630 50 251 1.97E-8 T 29-03-2018 IPR021109 Aspartic peptidase domain GBCGDNIH2_RS04565 6d80374436ae30e253a7ecbda6bb7710 250 SUPERFAMILY SSF53335 34 176 5.83E-23 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GBCGDNIH2_RS04565 6d80374436ae30e253a7ecbda6bb7710 250 Gene3D G3DSA:3.40.50.150 31 243 5.5E-30 T 29-03-2018 GBCGDNIH2_RS04565 6d80374436ae30e253a7ecbda6bb7710 250 Pfam PF05175 Methyltransferase small domain 34 132 4.0E-8 T 29-03-2018 IPR007848 Methyltransferase small domain GO:0008168 GBCGDNIH2_RS01620 d632f02d242b8cd4f5a9ff1f3f9dac80 110 PRINTS PR00354 7Fe ferredoxin signature 35 52 1.6E-17 T 29-03-2018 IPR000813 7Fe ferredoxin GO:0009055 GBCGDNIH2_RS01620 d632f02d242b8cd4f5a9ff1f3f9dac80 110 PRINTS PR00354 7Fe ferredoxin signature 9 19 1.6E-17 T 29-03-2018 IPR000813 7Fe ferredoxin GO:0009055 GBCGDNIH2_RS01620 d632f02d242b8cd4f5a9ff1f3f9dac80 110 PRINTS PR00354 7Fe ferredoxin signature 19 29 1.6E-17 T 29-03-2018 IPR000813 7Fe ferredoxin GO:0009055 GBCGDNIH2_RS01620 d632f02d242b8cd4f5a9ff1f3f9dac80 110 SUPERFAMILY SSF54862 3 97 2.65E-22 T 29-03-2018 GBCGDNIH2_RS01620 d632f02d242b8cd4f5a9ff1f3f9dac80 110 Pfam PF12800 4Fe-4S binding domain 7 23 0.7 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain GBCGDNIH2_RS01620 d632f02d242b8cd4f5a9ff1f3f9dac80 110 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site GBCGDNIH2_RS01620 d632f02d242b8cd4f5a9ff1f3f9dac80 110 Pfam PF11953 Domain of unknown function (DUF3470) 65 103 4.7E-17 T 29-03-2018 IPR022569 Ferredoxin, C-terminal GBCGDNIH2_RS01620 d632f02d242b8cd4f5a9ff1f3f9dac80 110 Gene3D G3DSA:3.30.70.20 2 44 2.9E-12 T 29-03-2018 GBCGDNIH2_RS01620 d632f02d242b8cd4f5a9ff1f3f9dac80 110 Gene3D G3DSA:3.30.70.20 45 106 4.5E-11 T 29-03-2018 GBCGDNIH2_RS01620 d632f02d242b8cd4f5a9ff1f3f9dac80 110 Pfam PF00037 4Fe-4S binding domain 34 55 3.7E-7 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain GBCGDNIH2_RS01075 c947cf98d998fe411f1d788c04fc357e 595 Pfam PF02938 GAD domain 315 406 1.5E-16 T 29-03-2018 IPR029351 GAD domain Reactome: R-HSA-379726 GBCGDNIH2_RS01075 c947cf98d998fe411f1d788c04fc357e 595 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 5 586 1.7E-177 T 29-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 GBCGDNIH2_RS01075 c947cf98d998fe411f1d788c04fc357e 595 Gene3D G3DSA:2.40.50.140 1 109 1.5E-25 T 29-03-2018 GBCGDNIH2_RS01075 c947cf98d998fe411f1d788c04fc357e 595 SUPERFAMILY SSF50249 4 107 3.64E-28 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold GBCGDNIH2_RS01075 c947cf98d998fe411f1d788c04fc357e 595 PRINTS PR01042 Aspartyl-tRNA synthetase signature 211 224 2.7E-20 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 GBCGDNIH2_RS01075 c947cf98d998fe411f1d788c04fc357e 595 PRINTS PR01042 Aspartyl-tRNA synthetase signature 194 206 2.7E-20 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 GBCGDNIH2_RS01075 c947cf98d998fe411f1d788c04fc357e 595 PRINTS PR01042 Aspartyl-tRNA synthetase signature 477 493 2.7E-20 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 GBCGDNIH2_RS01075 c947cf98d998fe411f1d788c04fc357e 595 PRINTS PR01042 Aspartyl-tRNA synthetase signature 521 535 2.7E-20 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 GBCGDNIH2_RS01075 c947cf98d998fe411f1d788c04fc357e 595 Gene3D G3DSA:3.30.930.10 135 589 2.8E-94 T 29-03-2018 GBCGDNIH2_RS01075 c947cf98d998fe411f1d788c04fc357e 595 Pfam PF01336 OB-fold nucleic acid binding domain 23 100 3.1E-15 T 29-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 GBCGDNIH2_RS01075 c947cf98d998fe411f1d788c04fc357e 595 Pfam PF00152 tRNA synthetases class II (D, K and N) 123 560 6.3E-93 T 29-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 GBCGDNIH2_RS01075 c947cf98d998fe411f1d788c04fc357e 595 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 4 587 29.95 T 29-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 GBCGDNIH2_RS01075 c947cf98d998fe411f1d788c04fc357e 595 SUPERFAMILY SSF55681 117 299 3.58E-95 T 29-03-2018 GBCGDNIH2_RS01075 c947cf98d998fe411f1d788c04fc357e 595 SUPERFAMILY SSF55681 427 586 3.58E-95 T 29-03-2018 GBCGDNIH2_RS01075 c947cf98d998fe411f1d788c04fc357e 595 SUPERFAMILY SSF55261 296 422 3.11E-36 T 29-03-2018 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 GBCGDNIH2_RS12375 311a4d5d43f70e763e77962e4bc6d609 517 Gene3D G3DSA:1.10.645.10 157 316 2.2E-32 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS12375 311a4d5d43f70e763e77962e4bc6d609 517 Gene3D G3DSA:1.10.645.10 360 508 1.1E-19 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS12375 311a4d5d43f70e763e77962e4bc6d609 517 SUPERFAMILY SSF143243 63 173 3.14E-10 T 29-03-2018 GBCGDNIH2_RS12375 311a4d5d43f70e763e77962e4bc6d609 517 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 274 437 1.7E-19 T 29-03-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS12375 311a4d5d43f70e763e77962e4bc6d609 517 Pfam PF00374 Nickel-dependent hydrogenase 197 262 1.9E-7 T 29-03-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 GBCGDNIH2_RS12375 311a4d5d43f70e763e77962e4bc6d609 517 SUPERFAMILY SSF56762 170 516 4.19E-73 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS01065 abafcee2fefcd001ad64b46127ce117c 395 SUPERFAMILY SSF47819 201 306 6.92E-21 T 29-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 GBCGDNIH2_RS01065 abafcee2fefcd001ad64b46127ce117c 395 SUPERFAMILY SSF53098 11 214 2.15E-66 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 GBCGDNIH2_RS01065 abafcee2fefcd001ad64b46127ce117c 395 Gene3D G3DSA:3.30.420.10 11 203 5.7E-41 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 GBCGDNIH2_RS01065 abafcee2fefcd001ad64b46127ce117c 395 Gene3D G3DSA:1.10.150.80 205 317 1.2E-18 T 29-03-2018 GBCGDNIH2_RS01065 abafcee2fefcd001ad64b46127ce117c 395 TIGRFAM TIGR01388 rnd: ribonuclease D 14 377 3.1E-117 T 29-03-2018 IPR006292 Ribonuclease D GO:0008033|GO:0008408|GO:0033890 GBCGDNIH2_RS01065 abafcee2fefcd001ad64b46127ce117c 395 Hamap MF_01899 Ribonuclease D [rnd]. 12 377 44.972 T 29-03-2018 IPR006292 Ribonuclease D GO:0008033|GO:0008408|GO:0033890 GBCGDNIH2_RS01065 abafcee2fefcd001ad64b46127ce117c 395 Pfam PF00570 HRDC domain 224 290 1.6E-14 T 29-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 GBCGDNIH2_RS01065 abafcee2fefcd001ad64b46127ce117c 395 Pfam PF01612 3'-5' exonuclease 14 181 9.0E-36 T 29-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 GBCGDNIH2_RS01065 abafcee2fefcd001ad64b46127ce117c 395 SMART SM00341 219 300 6.3E-6 T 29-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 GBCGDNIH2_RS01065 abafcee2fefcd001ad64b46127ce117c 395 SUPERFAMILY SSF47819 316 380 2.24E-13 T 29-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 GBCGDNIH2_RS01065 abafcee2fefcd001ad64b46127ce117c 395 SMART SM00474 12 181 8.8E-33 T 29-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 GBCGDNIH2_RS10685 b97731141b256864680ac6905410271e 156 Pfam PF06319 DNA repair protein MmcB-like 8 143 5.0E-48 T 29-03-2018 IPR009394 DNA repair protein MmcB-like GBCGDNIH2_RS10685 b97731141b256864680ac6905410271e 156 PIRSF PIRSF031796 5 150 1.8E-42 T 29-03-2018 IPR009394 DNA repair protein MmcB-like GBCGDNIH2_RS05835 4d4af679a3d280137e24b844df7985de 255 SUPERFAMILY SSF51556 1 252 2.56E-83 T 29-03-2018 IPR032466 Metal-dependent hydrolase GBCGDNIH2_RS05835 4d4af679a3d280137e24b844df7985de 255 ProSitePatterns PS01090 TatD deoxyribonuclease family signature 2. 122 132 - T 29-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 GBCGDNIH2_RS05835 4d4af679a3d280137e24b844df7985de 255 Gene3D G3DSA:3.20.20.140 1 255 2.9E-80 T 29-03-2018 GBCGDNIH2_RS05835 4d4af679a3d280137e24b844df7985de 255 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 2 10 - T 29-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 GBCGDNIH2_RS05835 4d4af679a3d280137e24b844df7985de 255 PIRSF PIRSF005902 1 255 6.4E-72 T 29-03-2018 IPR001130 TatD family GO:0016788 GBCGDNIH2_RS05835 4d4af679a3d280137e24b844df7985de 255 Pfam PF01026 TatD related DNase 3 251 7.4E-74 T 29-03-2018 IPR001130 TatD family GO:0016788 GBCGDNIH2_RS05835 4d4af679a3d280137e24b844df7985de 255 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 2 252 3.9E-77 T 29-03-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 GBCGDNIH2_RS06810 73cf5228142a98edbe4d5216abcdd330 330 Gene3D G3DSA:1.10.3720.10 20 326 1.1E-19 T 29-03-2018 GBCGDNIH2_RS06810 73cf5228142a98edbe4d5216abcdd330 330 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 152 316 1.7E-13 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GBCGDNIH2_RS06810 73cf5228142a98edbe4d5216abcdd330 330 SUPERFAMILY SSF161098 126 306 2.22E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GBCGDNIH2_RS09660 01969bacf28d7d7c093b11dd32e9c724 825 SUPERFAMILY SSF82861 581 645 1.57E-12 T 29-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 GBCGDNIH2_RS09660 01969bacf28d7d7c093b11dd32e9c724 825 SUPERFAMILY SSF82689 715 813 6.28E-12 T 29-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 GBCGDNIH2_RS09660 01969bacf28d7d7c093b11dd32e9c724 825 Pfam PF00924 Mechanosensitive ion channel 604 804 3.2E-38 T 29-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 GBCGDNIH2_RS09660 01969bacf28d7d7c093b11dd32e9c724 825 SUPERFAMILY SSF50182 647 708 1.31E-11 T 29-03-2018 IPR010920 LSM domain GBCGDNIH2_RS09660 01969bacf28d7d7c093b11dd32e9c724 825 Gene3D G3DSA:3.30.70.100 711 809 9.5E-11 T 29-03-2018 GBCGDNIH2_RS09660 01969bacf28d7d7c093b11dd32e9c724 825 Gene3D G3DSA:2.30.30.60 663 710 1.2E-7 T 29-03-2018 GBCGDNIH2_RS10030 e2969d6d8a465700e9d35236d4b5333d 143 Gene3D G3DSA:1.10.760.10 18 142 1.9E-14 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 GBCGDNIH2_RS10030 e2969d6d8a465700e9d35236d4b5333d 143 SUPERFAMILY SSF46626 5 129 1.36E-17 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 GBCGDNIH2_RS10030 e2969d6d8a465700e9d35236d4b5333d 143 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 45 110 4.4E-9 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 GBCGDNIH2_RS04495 8035e8283fc826f3d83623f3f6c7ccca 502 SMART SM00079 25 247 0.0012 T 29-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 GBCGDNIH2_RS04495 8035e8283fc826f3d83623f3f6c7ccca 502 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 290 387 1.1E-29 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 GBCGDNIH2_RS04495 8035e8283fc826f3d83623f3f6c7ccca 502 SMART SM00062 25 246 1.6E-47 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF GBCGDNIH2_RS04495 8035e8283fc826f3d83623f3f6c7ccca 502 SUPERFAMILY SSF161098 291 478 1.28E-42 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GBCGDNIH2_RS04495 8035e8283fc826f3d83623f3f6c7ccca 502 SUPERFAMILY SSF53850 1 243 3.31E-57 T 29-03-2018 GBCGDNIH2_RS04495 8035e8283fc826f3d83623f3f6c7ccca 502 Gene3D G3DSA:1.10.3720.10 197 498 2.7E-44 T 29-03-2018 GBCGDNIH2_RS04495 8035e8283fc826f3d83623f3f6c7ccca 502 Gene3D G3DSA:3.40.190.10 17 127 2.8E-21 T 29-03-2018 GBCGDNIH2_RS04495 8035e8283fc826f3d83623f3f6c7ccca 502 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 312 492 8.1E-21 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GBCGDNIH2_RS04495 8035e8283fc826f3d83623f3f6c7ccca 502 Gene3D G3DSA:3.40.190.10 128 196 1.4E-17 T 29-03-2018 GBCGDNIH2_RS04495 8035e8283fc826f3d83623f3f6c7ccca 502 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 29 242 9.2E-53 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF GBCGDNIH2_RS05235 2e82e4c5c9e07fac157de6bb897e2d12 305 SUPERFAMILY SSF51735 10 298 2.99E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS05235 2e82e4c5c9e07fac157de6bb897e2d12 305 Pfam PF13460 NAD(P)H-binding 15 102 2.6E-10 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS05235 2e82e4c5c9e07fac157de6bb897e2d12 305 Gene3D G3DSA:3.40.50.720 11 305 1.4E-29 T 29-03-2018 GBCGDNIH2_RS09555 be1df369a2872c7bf2f539928574d7d8 453 SUPERFAMILY SSF51905 1 239 1.47E-49 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS09555 be1df369a2872c7bf2f539928574d7d8 453 Gene3D G3DSA:3.50.50.60 1 445 7.5E-66 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS09555 be1df369a2872c7bf2f539928574d7d8 453 SUPERFAMILY SSF51905 255 389 4.14E-7 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS09555 be1df369a2872c7bf2f539928574d7d8 453 Pfam PF00743 Flavin-binding monooxygenase-like 244 381 3.7E-8 T 29-03-2018 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 GBCGDNIH2_RS09555 be1df369a2872c7bf2f539928574d7d8 453 Pfam PF00743 Flavin-binding monooxygenase-like 2 220 2.3E-30 T 29-03-2018 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 GBCGDNIH2_RS09555 be1df369a2872c7bf2f539928574d7d8 453 PIRSF PIRSF000332 1 231 4.2E-36 T 29-03-2018 GBCGDNIH2_RS09555 be1df369a2872c7bf2f539928574d7d8 453 PIRSF PIRSF000332 241 402 3.8E-11 T 29-03-2018 GBCGDNIH2_RS05805 bc5cbc823a6cb135f9293fb7d83194ef 419 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 68 287 8.6E-69 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 GBCGDNIH2_RS05805 bc5cbc823a6cb135f9293fb7d83194ef 419 Gene3D G3DSA:2.60.410.10 329 401 1.3E-17 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 GBCGDNIH2_RS05805 bc5cbc823a6cb135f9293fb7d83194ef 419 SUPERFAMILY SSF56601 64 311 4.98E-69 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like GBCGDNIH2_RS05805 bc5cbc823a6cb135f9293fb7d83194ef 419 SMART SM00936 311 401 3.5E-28 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 GBCGDNIH2_RS05805 bc5cbc823a6cb135f9293fb7d83194ef 419 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 311 401 4.4E-17 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 GBCGDNIH2_RS05805 bc5cbc823a6cb135f9293fb7d83194ef 419 Gene3D G3DSA:3.40.710.10 35 328 1.8E-50 T 29-03-2018 GBCGDNIH2_RS05805 bc5cbc823a6cb135f9293fb7d83194ef 419 SUPERFAMILY SSF69189 311 401 6.87E-19 T 29-03-2018 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 GBCGDNIH2_RS05805 bc5cbc823a6cb135f9293fb7d83194ef 419 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 99 110 2.2E-18 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 GBCGDNIH2_RS05805 bc5cbc823a6cb135f9293fb7d83194ef 419 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 152 169 2.2E-18 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 GBCGDNIH2_RS05805 bc5cbc823a6cb135f9293fb7d83194ef 419 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 179 192 2.2E-18 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 GBCGDNIH2_RS06010 a8e99fbfbe9073fd74172f4cb4e220bb 457 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 3 447 46.496 T 29-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GBCGDNIH2_RS06010 a8e99fbfbe9073fd74172f4cb4e220bb 457 Gene3D G3DSA:3.40.120.10 273 377 9.4E-30 T 29-03-2018 GBCGDNIH2_RS06010 a8e99fbfbe9073fd74172f4cb4e220bb 457 SUPERFAMILY SSF55957 362 444 2.35E-18 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GBCGDNIH2_RS06010 a8e99fbfbe9073fd74172f4cb4e220bb 457 SUPERFAMILY SSF53738 261 367 1.18E-31 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GBCGDNIH2_RS06010 a8e99fbfbe9073fd74172f4cb4e220bb 457 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 160 257 2.6E-17 T 29-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GBCGDNIH2_RS06010 a8e99fbfbe9073fd74172f4cb4e220bb 457 Gene3D G3DSA:3.30.310.50 378 447 3.6E-14 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GBCGDNIH2_RS06010 a8e99fbfbe9073fd74172f4cb4e220bb 457 Gene3D G3DSA:3.40.120.10 159 272 1.4E-30 T 29-03-2018 GBCGDNIH2_RS06010 a8e99fbfbe9073fd74172f4cb4e220bb 457 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 237 252 2.8E-13 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GBCGDNIH2_RS06010 a8e99fbfbe9073fd74172f4cb4e220bb 457 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 177 196 2.8E-13 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GBCGDNIH2_RS06010 a8e99fbfbe9073fd74172f4cb4e220bb 457 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 96 110 2.8E-13 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GBCGDNIH2_RS06010 a8e99fbfbe9073fd74172f4cb4e220bb 457 SUPERFAMILY SSF53738 159 259 6.67E-28 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GBCGDNIH2_RS06010 a8e99fbfbe9073fd74172f4cb4e220bb 457 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 97 106 - T 29-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GBCGDNIH2_RS06010 a8e99fbfbe9073fd74172f4cb4e220bb 457 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 391 444 1.0E-11 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GBCGDNIH2_RS06010 a8e99fbfbe9073fd74172f4cb4e220bb 457 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 7 444 7.2E-185 T 29-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GBCGDNIH2_RS06010 a8e99fbfbe9073fd74172f4cb4e220bb 457 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 261 367 7.2E-33 T 29-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GBCGDNIH2_RS06010 a8e99fbfbe9073fd74172f4cb4e220bb 457 SUPERFAMILY SSF53738 2 184 3.92E-46 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GBCGDNIH2_RS06010 a8e99fbfbe9073fd74172f4cb4e220bb 457 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 5 136 5.7E-42 T 29-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GBCGDNIH2_RS06010 a8e99fbfbe9073fd74172f4cb4e220bb 457 Gene3D G3DSA:3.40.120.10 1 146 6.1E-45 T 29-03-2018 GBCGDNIH2_RS06440 2507dc52062a5433d809cc06ee66e999 296 Pfam PF00701 Dihydrodipicolinate synthetase family 2 286 2.1E-98 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 GBCGDNIH2_RS06440 2507dc52062a5433d809cc06ee66e999 296 SUPERFAMILY SSF51569 2 289 1.36E-109 T 29-03-2018 GBCGDNIH2_RS06440 2507dc52062a5433d809cc06ee66e999 296 SMART SM01130 1 289 1.4E-149 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 GBCGDNIH2_RS06440 2507dc52062a5433d809cc06ee66e999 296 Gene3D G3DSA:3.20.20.70 1 296 1.0E-108 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS06440 2507dc52062a5433d809cc06ee66e999 296 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 1 287 65.303 T 29-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 GBCGDNIH2_RS06440 2507dc52062a5433d809cc06ee66e999 296 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 5 286 3.5E-105 T 29-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 GBCGDNIH2_RS06440 2507dc52062a5433d809cc06ee66e999 296 PRINTS PR00146 Dihydrodipicolinate synthase signature 35 56 2.1E-31 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 GBCGDNIH2_RS06440 2507dc52062a5433d809cc06ee66e999 296 PRINTS PR00146 Dihydrodipicolinate synthase signature 103 119 2.1E-31 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 GBCGDNIH2_RS06440 2507dc52062a5433d809cc06ee66e999 296 PRINTS PR00146 Dihydrodipicolinate synthase signature 128 145 2.1E-31 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 GBCGDNIH2_RS06440 2507dc52062a5433d809cc06ee66e999 296 PRINTS PR00146 Dihydrodipicolinate synthase signature 71 89 2.1E-31 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 GBCGDNIH2_RS06440 2507dc52062a5433d809cc06ee66e999 296 PIRSF PIRSF001365 1 295 2.2E-95 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 GBCGDNIH2_RS06440 2507dc52062a5433d809cc06ee66e999 296 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 38 55 - T 29-03-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 GBCGDNIH2_RS06440 2507dc52062a5433d809cc06ee66e999 296 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 133 163 - T 29-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 GBCGDNIH2_RS11010 bb4eeb885df67d6c55d4d2967b8ecdb1 273 SUPERFAMILY SSF69572 17 269 1.96E-87 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 GBCGDNIH2_RS11010 bb4eeb885df67d6c55d4d2967b8ecdb1 273 Gene3D G3DSA:3.40.50.720 16 268 8.6E-71 T 29-03-2018 GBCGDNIH2_RS11010 bb4eeb885df67d6c55d4d2967b8ecdb1 273 Pfam PF00899 ThiF family 27 265 9.6E-63 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 GBCGDNIH2_RS12575 2344434b9595edb0afba0950dec47007 323 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 181 202 - T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 GBCGDNIH2_RS12575 2344434b9595edb0afba0950dec47007 323 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 166 190 8.4E-34 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 GBCGDNIH2_RS12575 2344434b9595edb0afba0950dec47007 323 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 126 146 8.4E-34 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 GBCGDNIH2_RS12575 2344434b9595edb0afba0950dec47007 323 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 11 28 8.4E-34 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 GBCGDNIH2_RS12575 2344434b9595edb0afba0950dec47007 323 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 231 248 8.4E-34 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 GBCGDNIH2_RS12575 2344434b9595edb0afba0950dec47007 323 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 191 215 8.4E-34 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 GBCGDNIH2_RS12575 2344434b9595edb0afba0950dec47007 323 PIRSF PIRSF000114 2 323 1.2E-75 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 GBCGDNIH2_RS12575 2344434b9595edb0afba0950dec47007 323 Gene3D G3DSA:1.10.1040.10 178 322 3.2E-39 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 GBCGDNIH2_RS12575 2344434b9595edb0afba0950dec47007 323 SUPERFAMILY SSF48179 173 323 1.29E-42 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 GBCGDNIH2_RS12575 2344434b9595edb0afba0950dec47007 323 SUPERFAMILY SSF51735 7 173 9.27E-35 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS12575 2344434b9595edb0afba0950dec47007 323 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 9 151 7.6E-32 T 29-03-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 GBCGDNIH2_RS12575 2344434b9595edb0afba0950dec47007 323 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 173 312 4.2E-38 T 29-03-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 GBCGDNIH2_RS12575 2344434b9595edb0afba0950dec47007 323 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 7 314 31.625 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 GBCGDNIH2_RS12575 2344434b9595edb0afba0950dec47007 323 Gene3D G3DSA:3.40.50.720 7 177 7.0E-26 T 29-03-2018 GBCGDNIH2_RS10885 805f1d2b68032de69731b4d12a2b04cf 123 Pfam PF13833 EF-hand domain pair 10 39 0.0037 T 29-03-2018 IPR002048 EF-hand domain GO:0005509 GBCGDNIH2_RS10885 805f1d2b68032de69731b4d12a2b04cf 123 Pfam PF13202 EF hand 44 61 0.04 T 29-03-2018 IPR002048 EF-hand domain GO:0005509 GBCGDNIH2_RS10885 805f1d2b68032de69731b4d12a2b04cf 123 Pfam PF13202 EF hand 89 110 8.5E-4 T 29-03-2018 IPR002048 EF-hand domain GO:0005509 GBCGDNIH2_RS10885 805f1d2b68032de69731b4d12a2b04cf 123 Gene3D G3DSA:1.10.238.10 55 96 1.9E-11 T 29-03-2018 GBCGDNIH2_RS10885 805f1d2b68032de69731b4d12a2b04cf 123 ProSitePatterns PS00018 EF-hand calcium-binding domain. 73 85 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site GBCGDNIH2_RS10885 805f1d2b68032de69731b4d12a2b04cf 123 SUPERFAMILY SSF47473 23 109 1.63E-16 T 29-03-2018 IPR011992 EF-hand domain pair GBCGDNIH2_RS10885 805f1d2b68032de69731b4d12a2b04cf 123 Gene3D G3DSA:1.10.238.10 97 117 0.018 T 29-03-2018 GBCGDNIH2_RS10885 805f1d2b68032de69731b4d12a2b04cf 123 ProSitePatterns PS00018 EF-hand calcium-binding domain. 48 60 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site GBCGDNIH2_RS10885 805f1d2b68032de69731b4d12a2b04cf 123 Gene3D G3DSA:1.10.238.10 3 31 0.0025 T 29-03-2018 GBCGDNIH2_RS10885 805f1d2b68032de69731b4d12a2b04cf 123 Gene3D G3DSA:1.10.1330.10 32 54 3.6E-5 T 29-03-2018 GBCGDNIH2_RS00860 5ff2856491e3f5f3db8376a0b415d52a 327 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 13 186 6.6E-58 T 29-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain GBCGDNIH2_RS00860 5ff2856491e3f5f3db8376a0b415d52a 327 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 231 323 5.6E-21 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal GBCGDNIH2_RS00860 5ff2856491e3f5f3db8376a0b415d52a 327 Gene3D G3DSA:3.30.1220.10 214 324 1.0E-27 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal GBCGDNIH2_RS00860 5ff2856491e3f5f3db8376a0b415d52a 327 Gene3D G3DSA:3.40.50.300 10 208 7.4E-50 T 29-03-2018 GBCGDNIH2_RS00860 5ff2856491e3f5f3db8376a0b415d52a 327 SMART SM00833 231 323 4.8E-16 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal GBCGDNIH2_RS00860 5ff2856491e3f5f3db8376a0b415d52a 327 SUPERFAMILY SSF52540 12 212 3.95E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS00860 5ff2856491e3f5f3db8376a0b415d52a 327 SUPERFAMILY SSF90002 231 323 8.76E-24 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal GBCGDNIH2_RS03160 ab12e9f625c0550a29f79a93e672f739 792 Gene3D G3DSA:2.40.170.20 191 792 1.6E-76 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 GBCGDNIH2_RS03160 ab12e9f625c0550a29f79a93e672f739 792 Pfam PF07715 TonB-dependent Receptor Plug Domain 68 179 1.6E-9 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 GBCGDNIH2_RS03160 ab12e9f625c0550a29f79a93e672f739 792 Pfam PF00593 TonB dependent receptor 287 765 5.0E-42 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 GBCGDNIH2_RS03160 ab12e9f625c0550a29f79a93e672f739 792 Gene3D G3DSA:2.170.130.10 41 190 1.0E-11 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 GBCGDNIH2_RS03160 ab12e9f625c0550a29f79a93e672f739 792 SUPERFAMILY SSF56935 47 792 5.86E-91 T 29-03-2018 GBCGDNIH2_RS05385 3941e221309583e7ae217db605a49ce4 250 TIGRFAM TIGR00613 reco: DNA repair protein RecO 7 224 8.0E-24 T 29-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 GBCGDNIH2_RS05385 3941e221309583e7ae217db605a49ce4 250 ProDom PD202328 DNA REPAIR RECOMBINATION RECO DAMAGE O O RECO-RELATED RECOMBINATIONAL RP549 134 235 9.0E-15 T 29-03-2018 GBCGDNIH2_RS05385 3941e221309583e7ae217db605a49ce4 250 SUPERFAMILY SSF50249 1 70 5.48E-7 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold GBCGDNIH2_RS05385 3941e221309583e7ae217db605a49ce4 250 Pfam PF11967 Recombination protein O N terminal 1 76 7.3E-15 T 29-03-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal GBCGDNIH2_RS05385 3941e221309583e7ae217db605a49ce4 250 Gene3D G3DSA:2.40.50.140 1 75 6.5E-13 T 29-03-2018 GBCGDNIH2_RS05385 3941e221309583e7ae217db605a49ce4 250 Hamap MF_00201 DNA repair protein RecO [recO]. 1 239 15.772 T 29-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 GBCGDNIH2_RS05385 3941e221309583e7ae217db605a49ce4 250 SUPERFAMILY SSF57863 87 184 2.07E-9 T 29-03-2018 GBCGDNIH2_RS05385 3941e221309583e7ae217db605a49ce4 250 Pfam PF02565 Recombination protein O C terminal 83 222 4.2E-23 T 29-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 GBCGDNIH2_RS05140 26eb8ae9b2eb0f7c970298c82304a62e 283 Pfam PF13720 Udp N-acetylglucosamine O-acyltransferase; Domain 2 185 271 6.9E-23 T 29-03-2018 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 GBCGDNIH2_RS05140 26eb8ae9b2eb0f7c970298c82304a62e 283 Gene3D G3DSA:2.160.10.10 5 201 9.8E-43 T 29-03-2018 GBCGDNIH2_RS05140 26eb8ae9b2eb0f7c970298c82304a62e 283 PIRSF PIRSF000456 9 279 3.0E-102 T 29-03-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 GBCGDNIH2_RS05140 26eb8ae9b2eb0f7c970298c82304a62e 283 Gene3D G3DSA:1.20.1180.10 203 282 1.3E-19 T 29-03-2018 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 GBCGDNIH2_RS05140 26eb8ae9b2eb0f7c970298c82304a62e 283 Hamap MF_00387 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase [lpxA]. 10 272 42.422 T 29-03-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 GBCGDNIH2_RS05140 26eb8ae9b2eb0f7c970298c82304a62e 283 TIGRFAM TIGR01852 lipid_A_lpxA: acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase 13 270 5.9E-99 T 29-03-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 GBCGDNIH2_RS05140 26eb8ae9b2eb0f7c970298c82304a62e 283 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 114 148 1.4E-9 T 29-03-2018 IPR001451 Hexapeptide repeat GBCGDNIH2_RS05140 26eb8ae9b2eb0f7c970298c82304a62e 283 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 22 56 8.1E-6 T 29-03-2018 IPR001451 Hexapeptide repeat GBCGDNIH2_RS05140 26eb8ae9b2eb0f7c970298c82304a62e 283 SUPERFAMILY SSF51161 11 263 2.17E-68 T 29-03-2018 IPR011004 Trimeric LpxA-like GBCGDNIH2_RS03660 453b40088ceecfa831cc72de96f159d0 400 Pfam PF00155 Aminotransferase class I and II 32 392 7.6E-80 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 GBCGDNIH2_RS03660 453b40088ceecfa831cc72de96f159d0 400 SUPERFAMILY SSF53383 1 396 2.34E-115 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase GBCGDNIH2_RS03660 453b40088ceecfa831cc72de96f159d0 400 Gene3D G3DSA:3.40.640.10 63 274 6.1E-48 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GBCGDNIH2_RS03660 453b40088ceecfa831cc72de96f159d0 400 Gene3D G3DSA:3.90.1150.10 275 400 4.4E-37 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 GBCGDNIH2_RS03660 453b40088ceecfa831cc72de96f159d0 400 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 236 249 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 GBCGDNIH2_RS11115 ffaa0f6cd8bd441157f1b0447866c4f7 421 Pfam PF01494 FAD binding domain 19 375 3.0E-32 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 GBCGDNIH2_RS11115 ffaa0f6cd8bd441157f1b0447866c4f7 421 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 182 197 1.6E-18 T 29-03-2018 GBCGDNIH2_RS11115 ffaa0f6cd8bd441157f1b0447866c4f7 421 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 326 342 1.6E-18 T 29-03-2018 GBCGDNIH2_RS11115 ffaa0f6cd8bd441157f1b0447866c4f7 421 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 20 42 1.6E-18 T 29-03-2018 GBCGDNIH2_RS11115 ffaa0f6cd8bd441157f1b0447866c4f7 421 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 311 326 1.6E-18 T 29-03-2018 GBCGDNIH2_RS11115 ffaa0f6cd8bd441157f1b0447866c4f7 421 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 20 421 3.7E-118 T 29-03-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 GBCGDNIH2_RS11115 ffaa0f6cd8bd441157f1b0447866c4f7 421 Gene3D G3DSA:3.50.50.60 17 395 3.2E-43 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS11115 ffaa0f6cd8bd441157f1b0447866c4f7 421 SUPERFAMILY SSF51905 19 203 1.78E-55 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS11115 ffaa0f6cd8bd441157f1b0447866c4f7 421 SUPERFAMILY SSF51905 298 417 1.78E-55 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS11115 ffaa0f6cd8bd441157f1b0447866c4f7 421 ProSitePatterns PS01304 ubiH/COQ6 monooxygenase family signature. 325 338 - T 29-03-2018 IPR018168 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site GO:0016709|GO:0055114 Reactome: R-HSA-2142789 GBCGDNIH2_RS06555 07f2365b14ceaa281e1f713acc491ee6 167 PIRSF PIRSF001467 3 165 1.6E-31 T 29-03-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 GBCGDNIH2_RS06555 07f2365b14ceaa281e1f713acc491ee6 167 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 49 66 - T 29-03-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 GBCGDNIH2_RS06555 07f2365b14ceaa281e1f713acc491ee6 167 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 110 122 1.5E-14 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 GBCGDNIH2_RS06555 07f2365b14ceaa281e1f713acc491ee6 167 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 54 66 1.5E-14 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 GBCGDNIH2_RS06555 07f2365b14ceaa281e1f713acc491ee6 167 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 28 43 1.5E-14 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 GBCGDNIH2_RS06555 07f2365b14ceaa281e1f713acc491ee6 167 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 123 138 1.5E-14 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 GBCGDNIH2_RS06555 07f2365b14ceaa281e1f713acc491ee6 167 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 21 161 1.0E-47 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 GBCGDNIH2_RS06555 07f2365b14ceaa281e1f713acc491ee6 167 Gene3D G3DSA:2.40.100.10 1 167 3.5E-56 T 29-03-2018 IPR029000 Cyclophilin-like domain GBCGDNIH2_RS06555 07f2365b14ceaa281e1f713acc491ee6 167 SUPERFAMILY SSF50891 14 166 2.78E-52 T 29-03-2018 IPR029000 Cyclophilin-like domain GBCGDNIH2_RS07305 18a28c85fbbf847c92107125d924c581 173 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 12 166 1.1E-64 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 GBCGDNIH2_RS07305 18a28c85fbbf847c92107125d924c581 173 SUPERFAMILY SSF52255 11 164 2.49E-65 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 GBCGDNIH2_RS07305 18a28c85fbbf847c92107125d924c581 173 SMART SM01001 10 161 1.0E-102 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 GBCGDNIH2_RS07305 18a28c85fbbf847c92107125d924c581 173 Pfam PF00731 AIR carboxylase 12 158 7.6E-63 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 GBCGDNIH2_RS07305 18a28c85fbbf847c92107125d924c581 173 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 12 165 32.224 T 29-03-2018 IPR033747 Class I PurE GBCGDNIH2_RS07305 18a28c85fbbf847c92107125d924c581 173 Gene3D G3DSA:3.40.50.7700 2 170 5.1E-65 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 GBCGDNIH2_RS07305 18a28c85fbbf847c92107125d924c581 173 PIRSF PIRSF001338 7 171 1.6E-66 T 29-03-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 GBCGDNIH2_RS05435 77dad2d2ca7c29bc56141bc2760c04a4 168 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 21 159 1.5E-25 T 29-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 GBCGDNIH2_RS05435 77dad2d2ca7c29bc56141bc2760c04a4 168 Gene3D G3DSA:3.40.50.960 6 166 1.2E-42 T 29-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 GBCGDNIH2_RS05435 77dad2d2ca7c29bc56141bc2760c04a4 168 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 14 164 21.475 T 29-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 GBCGDNIH2_RS05435 77dad2d2ca7c29bc56141bc2760c04a4 168 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 20 161 4.0E-37 T 29-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 GBCGDNIH2_RS05435 77dad2d2ca7c29bc56141bc2760c04a4 168 SUPERFAMILY SSF52121 12 164 1.02E-39 T 29-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 GBCGDNIH2_RS05990 0fcd36d3bcae84abdee24d57adbecfc1 285 Gene3D G3DSA:1.20.5.320 25 144 2.1E-6 T 29-03-2018 GBCGDNIH2_RS05990 0fcd36d3bcae84abdee24d57adbecfc1 285 Gene3D G3DSA:1.25.40.10 145 282 7.7E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS05990 0fcd36d3bcae84abdee24d57adbecfc1 285 SUPERFAMILY SSF48452 164 270 6.24E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS05990 0fcd36d3bcae84abdee24d57adbecfc1 285 Pfam PF13432 Tetratricopeptide repeat 167 226 7.7E-7 T 29-03-2018 GBCGDNIH2_RS03925 32b847b2ffad0031fe872c9f331dd2a4 392 TIGRFAM TIGR00526 folB_dom: FolB domain 261 373 2.9E-17 T 29-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 GBCGDNIH2_RS03925 32b847b2ffad0031fe872c9f331dd2a4 392 Gene3D G3DSA:3.20.20.70 54 253 1.9E-5 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS03925 32b847b2ffad0031fe872c9f331dd2a4 392 Pfam PF02152 Dihydroneopterin aldolase 264 370 9.0E-21 T 29-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 GBCGDNIH2_RS03925 32b847b2ffad0031fe872c9f331dd2a4 392 Pfam PF04476 4-HFC-P synthase 4 224 2.1E-60 T 29-03-2018 IPR007565 (5-formylfuran-3-yl)methyl phosphate synthase KEGG: 00680+4.2.3.153|KEGG: 00902+4.2.3.15|MetaCyc: PWY-3041|MetaCyc: PWY-5254|MetaCyc: PWY-5423|MetaCyc: PWY-7410 GBCGDNIH2_RS03925 32b847b2ffad0031fe872c9f331dd2a4 392 SUPERFAMILY SSF51569 12 100 1.07E-5 T 29-03-2018 GBCGDNIH2_RS03925 32b847b2ffad0031fe872c9f331dd2a4 392 Gene3D G3DSA:3.20.20.70 3 53 0.014 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS03925 32b847b2ffad0031fe872c9f331dd2a4 392 SUPERFAMILY SSF55620 261 373 4.23E-22 T 29-03-2018 GBCGDNIH2_RS03925 32b847b2ffad0031fe872c9f331dd2a4 392 Gene3D G3DSA:3.30.1130.10 254 378 1.3E-25 T 29-03-2018 GBCGDNIH2_RS03925 32b847b2ffad0031fe872c9f331dd2a4 392 SMART SM00905 264 371 2.5E-28 T 29-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 GBCGDNIH2_RS02170 0ebcc6755f2341084d54a2bb8976e289 317 Pfam PF13525 Outer membrane lipoprotein 72 266 3.3E-58 T 29-03-2018 GBCGDNIH2_RS02170 0ebcc6755f2341084d54a2bb8976e289 317 SUPERFAMILY SSF48452 148 280 5.48E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS02170 0ebcc6755f2341084d54a2bb8976e289 317 SUPERFAMILY SSF48452 72 197 3.4E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS02170 0ebcc6755f2341084d54a2bb8976e289 317 Gene3D G3DSA:1.25.40.10 222 281 0.002 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS02170 0ebcc6755f2341084d54a2bb8976e289 317 Gene3D G3DSA:1.25.40.10 144 221 0.0014 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS02170 0ebcc6755f2341084d54a2bb8976e289 317 Hamap MF_00922 Outer membrane protein assembly factor BamD [bamD]. 39 274 34.782 T 29-03-2018 IPR017689 Outer membrane protein assembly factor BamD GBCGDNIH2_RS02170 0ebcc6755f2341084d54a2bb8976e289 317 TIGRFAM TIGR03302 OM_YfiO: outer membrane assembly lipoprotein YfiO 43 280 1.8E-86 T 29-03-2018 IPR017689 Outer membrane protein assembly factor BamD GBCGDNIH2_RS02170 0ebcc6755f2341084d54a2bb8976e289 317 Gene3D G3DSA:1.25.40.10 70 143 2.3E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS00765 8ba894b9672186fae25fd91c4fad774b 1163 SUPERFAMILY SSF82282 5 386 6.67E-100 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 GBCGDNIH2_RS00765 8ba894b9672186fae25fd91c4fad774b 1163 SUPERFAMILY SSF51717 345 612 1.07E-70 T 29-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 GBCGDNIH2_RS00765 8ba894b9672186fae25fd91c4fad774b 1163 PIRSF PIRSF000381 1 1163 0.0 T 29-03-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 GBCGDNIH2_RS00765 8ba894b9672186fae25fd91c4fad774b 1163 SUPERFAMILY SSF56507 890 1163 2.35E-86 T 29-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 GBCGDNIH2_RS00765 8ba894b9672186fae25fd91c4fad774b 1163 Gene3D G3DSA:1.10.1240.10 625 710 1.1E-31 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 GBCGDNIH2_RS00765 8ba894b9672186fae25fd91c4fad774b 1163 Gene3D G3DSA:3.10.196.10 1054 1163 3.2E-38 T 29-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 GBCGDNIH2_RS00765 8ba894b9672186fae25fd91c4fad774b 1163 Gene3D G3DSA:3.10.196.10 937 1053 1.5E-22 T 29-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 GBCGDNIH2_RS00765 8ba894b9672186fae25fd91c4fad774b 1163 TIGRFAM TIGR02082 metH: methionine synthase 11 1163 0.0 T 29-03-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 GBCGDNIH2_RS00765 8ba894b9672186fae25fd91c4fad774b 1163 Pfam PF02607 B12 binding domain 639 710 3.2E-25 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 GBCGDNIH2_RS00765 8ba894b9672186fae25fd91c4fad774b 1163 Gene3D G3DSA:3.20.20.330 1 317 1.6E-84 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 GBCGDNIH2_RS00765 8ba894b9672186fae25fd91c4fad774b 1163 SUPERFAMILY SSF52242 719 848 3.14E-37 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 GBCGDNIH2_RS00765 8ba894b9672186fae25fd91c4fad774b 1163 Pfam PF00809 Pterin binding enzyme 347 580 8.3E-37 T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 GBCGDNIH2_RS00765 8ba894b9672186fae25fd91c4fad774b 1163 Pfam PF02310 B12 binding domain 723 814 6.1E-19 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 GBCGDNIH2_RS00765 8ba894b9672186fae25fd91c4fad774b 1163 SMART SM01018 635 717 1.3E-38 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 GBCGDNIH2_RS00765 8ba894b9672186fae25fd91c4fad774b 1163 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 934 1163 3.5E-40 T 29-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 GBCGDNIH2_RS00765 8ba894b9672186fae25fd91c4fad774b 1163 SUPERFAMILY SSF47644 634 715 1.01E-23 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 GBCGDNIH2_RS00765 8ba894b9672186fae25fd91c4fad774b 1163 Pfam PF02574 Homocysteine S-methyltransferase 15 303 3.5E-60 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 GBCGDNIH2_RS00765 8ba894b9672186fae25fd91c4fad774b 1163 Gene3D G3DSA:3.20.20.20 332 624 3.3E-46 T 29-03-2018 GBCGDNIH2_RS00765 8ba894b9672186fae25fd91c4fad774b 1163 Gene3D G3DSA:3.40.50.280 711 879 1.1E-47 T 29-03-2018 GBCGDNIH2_RS07320 3569a0ca40277ca3bb609641e0742693 273 Gene3D G3DSA:3.40.50.1820 31 270 1.7E-38 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS07320 3569a0ca40277ca3bb609641e0742693 273 SUPERFAMILY SSF53474 38 270 6.4E-48 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS07320 3569a0ca40277ca3bb609641e0742693 273 Pfam PF01738 Dienelactone hydrolase family 48 270 2.2E-60 T 29-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 GBCGDNIH2_RS06800 224edc4ce7edd094a54b3bb3e210b4e2 391 Pfam PF07690 Major Facilitator Superfamily 9 321 1.1E-40 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 GBCGDNIH2_RS06800 224edc4ce7edd094a54b3bb3e210b4e2 391 Gene3D G3DSA:1.20.1250.20 193 387 1.1E-19 T 29-03-2018 GBCGDNIH2_RS06800 224edc4ce7edd094a54b3bb3e210b4e2 391 SUPERFAMILY SSF103473 3 376 1.83E-57 T 29-03-2018 IPR020846 Major facilitator superfamily domain GBCGDNIH2_RS06800 224edc4ce7edd094a54b3bb3e210b4e2 391 Gene3D G3DSA:1.20.1250.20 1 187 1.2E-28 T 29-03-2018 GBCGDNIH2_RS00475 28d0cde9cc5bba81b8bfe23d954ff558 169 Pfam PF05974 Domain of unknown function (DUF892) 7 163 2.1E-56 T 29-03-2018 IPR010287 Domain of unknown function DUF892 GBCGDNIH2_RS00475 28d0cde9cc5bba81b8bfe23d954ff558 169 Gene3D G3DSA:1.20.1260.10 1 167 1.0E-29 T 29-03-2018 IPR012347 Ferritin-related GBCGDNIH2_RS00475 28d0cde9cc5bba81b8bfe23d954ff558 169 SUPERFAMILY SSF47240 3 156 3.65E-50 T 29-03-2018 IPR009078 Ferritin-like superfamily GBCGDNIH2_RS12565 f192d6023e236c8e5d1cba188faca5c5 381 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 26 343 2.2E-89 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 GBCGDNIH2_RS12565 f192d6023e236c8e5d1cba188faca5c5 381 Pfam PF00814 Glycoprotease family 46 344 5.5E-92 T 29-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 GBCGDNIH2_RS12565 f192d6023e236c8e5d1cba188faca5c5 381 Gene3D G3DSA:3.30.420.40 23 174 3.8E-37 T 29-03-2018 GBCGDNIH2_RS12565 f192d6023e236c8e5d1cba188faca5c5 381 SUPERFAMILY SSF53067 25 348 1.3E-38 T 29-03-2018 GBCGDNIH2_RS12565 f192d6023e236c8e5d1cba188faca5c5 381 Gene3D G3DSA:3.30.420.40 175 326 1.9E-15 T 29-03-2018 GBCGDNIH2_RS12565 f192d6023e236c8e5d1cba188faca5c5 381 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 26 39 1.9E-31 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 GBCGDNIH2_RS12565 f192d6023e236c8e5d1cba188faca5c5 381 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 98 118 1.9E-31 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 GBCGDNIH2_RS12565 f192d6023e236c8e5d1cba188faca5c5 381 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 184 205 1.9E-31 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 GBCGDNIH2_RS12565 f192d6023e236c8e5d1cba188faca5c5 381 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 300 309 1.9E-31 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 GBCGDNIH2_RS12565 f192d6023e236c8e5d1cba188faca5c5 381 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 25 350 1.1E-116 T 29-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 GBCGDNIH2_RS12565 f192d6023e236c8e5d1cba188faca5c5 381 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 25 368 57.807 T 29-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 GBCGDNIH2_RS11440 5378c0a9307e50922a4902714b4813d3 213 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 14 190 3.2E-62 T 29-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 GBCGDNIH2_RS11440 5378c0a9307e50922a4902714b4813d3 213 SMART SM00072 11 193 7.1E-48 T 29-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit GBCGDNIH2_RS11440 5378c0a9307e50922a4902714b4813d3 213 ProSitePatterns PS00856 Guanylate kinase-like signature. 46 63 - T 29-03-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 GBCGDNIH2_RS11440 5378c0a9307e50922a4902714b4813d3 213 SUPERFAMILY SSF52540 10 196 6.99E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS11440 5378c0a9307e50922a4902714b4813d3 213 Gene3D G3DSA:3.40.50.300 7 194 8.6E-49 T 29-03-2018 GBCGDNIH2_RS11440 5378c0a9307e50922a4902714b4813d3 213 Hamap MF_00328 Guanylate kinase [gmk]. 10 193 32.702 T 29-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 GBCGDNIH2_RS11440 5378c0a9307e50922a4902714b4813d3 213 Pfam PF00625 Guanylate kinase 15 191 6.5E-40 T 29-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit GBCGDNIH2_RS05020 51c303b2adbced4d074eb8c29566c138 327 Pfam PF02625 XdhC and CoxI family 16 83 5.5E-25 T 29-03-2018 IPR003777 XdhC- CoxI GBCGDNIH2_RS05020 51c303b2adbced4d074eb8c29566c138 327 Pfam PF13478 XdhC Rossmann domain 170 311 5.6E-37 T 29-03-2018 IPR027051 XdhC Rossmann domain GBCGDNIH2_RS11060 0b28d58ad49b21e8a19db99bd1be1b1d 263 SUPERFAMILY SSF53850 35 261 1.73E-58 T 29-03-2018 GBCGDNIH2_RS11060 0b28d58ad49b21e8a19db99bd1be1b1d 263 Gene3D G3DSA:3.40.190.10 128 224 1.8E-31 T 29-03-2018 GBCGDNIH2_RS11060 0b28d58ad49b21e8a19db99bd1be1b1d 263 PIRSF PIRSF004846 1 263 6.4E-67 T 29-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 GBCGDNIH2_RS11060 0b28d58ad49b21e8a19db99bd1be1b1d 263 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 41 259 7.6E-59 T 29-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 GBCGDNIH2_RS11060 0b28d58ad49b21e8a19db99bd1be1b1d 263 Gene3D G3DSA:3.40.190.10 33 127 5.8E-10 T 29-03-2018 GBCGDNIH2_RS11060 0b28d58ad49b21e8a19db99bd1be1b1d 263 Pfam PF13531 Bacterial extracellular solute-binding protein 36 261 1.4E-37 T 29-03-2018 GBCGDNIH2_RS11545 6735b535521cefba458236dd7c0bb45c 128 PRINTS PR00332 Histidine triad family signature 14 30 1.6E-17 T 29-03-2018 IPR001310 Histidine triad (HIT) protein GBCGDNIH2_RS11545 6735b535521cefba458236dd7c0bb45c 128 PRINTS PR00332 Histidine triad family signature 35 53 1.6E-17 T 29-03-2018 IPR001310 Histidine triad (HIT) protein GBCGDNIH2_RS11545 6735b535521cefba458236dd7c0bb45c 128 PRINTS PR00332 Histidine triad family signature 104 114 1.6E-17 T 29-03-2018 IPR001310 Histidine triad (HIT) protein GBCGDNIH2_RS11545 6735b535521cefba458236dd7c0bb45c 128 Pfam PF01230 HIT domain 20 117 2.7E-25 T 29-03-2018 IPR001310 Histidine triad (HIT) protein GBCGDNIH2_RS11545 6735b535521cefba458236dd7c0bb45c 128 ProSitePatterns PS00892 HIT domain signature. 97 115 - T 29-03-2018 IPR019808 Histidine triad, conserved site GBCGDNIH2_RS11545 6735b535521cefba458236dd7c0bb45c 128 SUPERFAMILY SSF54197 9 122 2.32E-32 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 GBCGDNIH2_RS11545 6735b535521cefba458236dd7c0bb45c 128 Gene3D G3DSA:3.30.428.10 8 128 3.2E-29 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 GBCGDNIH2_RS04570 b6599961501290c926574a27704289cd 342 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 99 113 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site GBCGDNIH2_RS04570 b6599961501290c926574a27704289cd 342 SUPERFAMILY SSF48576 16 340 2.08E-94 T 29-03-2018 IPR008949 Isoprenoid synthase domain GBCGDNIH2_RS04570 b6599961501290c926574a27704289cd 342 Pfam PF00348 Polyprenyl synthetase 44 293 1.6E-72 T 29-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 GBCGDNIH2_RS04570 b6599961501290c926574a27704289cd 342 Gene3D G3DSA:1.10.600.10 6 342 2.9E-94 T 29-03-2018 IPR008949 Isoprenoid synthase domain GBCGDNIH2_RS11560 0282ecac7433e2591638a24febafa71c 242 Pfam PF00977 Histidine biosynthesis protein 5 230 4.7E-80 T 29-03-2018 IPR006062 Histidine biosynthesis GO:0000105 GBCGDNIH2_RS11560 0282ecac7433e2591638a24febafa71c 242 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 5 232 1.8E-78 T 29-03-2018 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 GBCGDNIH2_RS11560 0282ecac7433e2591638a24febafa71c 242 Gene3D G3DSA:3.20.20.70 3 242 9.8E-63 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS11560 0282ecac7433e2591638a24febafa71c 242 SUPERFAMILY SSF51366 4 237 1.28E-73 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 GBCGDNIH2_RS11560 0282ecac7433e2591638a24febafa71c 242 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 4 238 35.291 T 29-03-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 GBCGDNIH2_RS01405 d07bb7f48c96af04a7aed0cffdcc597f 385 Pfam PF07690 Major Facilitator Superfamily 16 330 2.8E-18 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 GBCGDNIH2_RS01405 d07bb7f48c96af04a7aed0cffdcc597f 385 Gene3D G3DSA:1.20.1250.20 206 379 3.9E-8 T 29-03-2018 GBCGDNIH2_RS01405 d07bb7f48c96af04a7aed0cffdcc597f 385 SUPERFAMILY SSF103473 7 374 1.7E-30 T 29-03-2018 IPR020846 Major facilitator superfamily domain GBCGDNIH2_RS01405 d07bb7f48c96af04a7aed0cffdcc597f 385 Gene3D G3DSA:1.20.1250.20 2 203 4.1E-14 T 29-03-2018 GBCGDNIH2_RS11625 a4d8272f4653fa9e84d7bc9d70f914ef 341 Gene3D G3DSA:3.20.20.70 173 329 0.039 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS11625 a4d8272f4653fa9e84d7bc9d70f914ef 341 Hamap MF_00409 Tetraacyldisaccharide 4'-kinase [lpxK]. 3 323 32.45 T 29-03-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 GBCGDNIH2_RS11625 a4d8272f4653fa9e84d7bc9d70f914ef 341 SUPERFAMILY SSF52540 49 176 5.31E-9 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS11625 a4d8272f4653fa9e84d7bc9d70f914ef 341 Pfam PF02606 Tetraacyldisaccharide-1-P 4'-kinase 15 316 2.3E-83 T 29-03-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 GBCGDNIH2_RS11625 a4d8272f4653fa9e84d7bc9d70f914ef 341 TIGRFAM TIGR00682 lpxK: tetraacyldisaccharide 4'-kinase 32 298 1.0E-52 T 29-03-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 GBCGDNIH2_RS11625 a4d8272f4653fa9e84d7bc9d70f914ef 341 Gene3D G3DSA:3.40.50.300 39 160 8.9E-4 T 29-03-2018 GBCGDNIH2_RS02255 196caf4bc59728389030757d73a626b6 156 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 156 35.912 T 29-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 GBCGDNIH2_RS02255 196caf4bc59728389030757d73a626b6 156 SUPERFAMILY SSF89447 1 140 4.71E-36 T 29-03-2018 GBCGDNIH2_RS02255 196caf4bc59728389030757d73a626b6 156 Gene3D G3DSA:2.10.260.10 7 42 0.004 T 29-03-2018 GBCGDNIH2_RS02255 196caf4bc59728389030757d73a626b6 156 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 4 126 7.0E-11 T 29-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 GBCGDNIH2_RS02255 196caf4bc59728389030757d73a626b6 156 Pfam PF02381 MraZ protein, putative antitoxin-like 82 131 1.9E-6 T 29-03-2018 IPR020603 MraZ domain GBCGDNIH2_RS02255 196caf4bc59728389030757d73a626b6 156 Pfam PF02381 MraZ protein, putative antitoxin-like 4 73 6.1E-7 T 29-03-2018 IPR020603 MraZ domain GBCGDNIH2_RS06380 cbc695f8959ce59656d7c51108121383 349 SUPERFAMILY SSF52518 25 344 3.93E-103 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold GBCGDNIH2_RS06380 cbc695f8959ce59656d7c51108121383 349 TIGRFAM TIGR03182 PDH_E1_alph_y: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 30 342 3.6E-146 T 29-03-2018 IPR017597 Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y GO:0004739|GO:0006086|GO:0043231 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-70268 GBCGDNIH2_RS06380 cbc695f8959ce59656d7c51108121383 349 Gene3D G3DSA:3.40.50.970 3 348 2.7E-92 T 29-03-2018 GBCGDNIH2_RS06380 cbc695f8959ce59656d7c51108121383 349 Pfam PF00676 Dehydrogenase E1 component 38 333 6.1E-105 T 29-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 GBCGDNIH2_RS10385 7b793eab2f488abb116eb6ac2ee692b4 368 Gene3D G3DSA:1.10.3720.10 13 332 3.2E-38 T 29-03-2018 GBCGDNIH2_RS10385 7b793eab2f488abb116eb6ac2ee692b4 368 SUPERFAMILY SSF161098 140 326 1.27E-17 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GBCGDNIH2_RS10385 7b793eab2f488abb116eb6ac2ee692b4 368 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 162 343 3.8E-25 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GBCGDNIH2_RS10385 7b793eab2f488abb116eb6ac2ee692b4 368 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 9 49 7.1E-6 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain GBCGDNIH2_RS05120 f87cb0d531201905ceebc8a351862926 816 Gene3D G3DSA:3.10.20.310 393 434 0.014 T 29-03-2018 GBCGDNIH2_RS05120 f87cb0d531201905ceebc8a351862926 816 Gene3D G3DSA:3.10.20.310 218 307 9.0E-20 T 29-03-2018 GBCGDNIH2_RS05120 f87cb0d531201905ceebc8a351862926 816 Hamap MF_01430 Outer membrane protein assembly factor BamA [bamA]. 58 816 23.061 T 29-03-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 GBCGDNIH2_RS05120 f87cb0d531201905ceebc8a351862926 816 TIGRFAM TIGR03303 OM_YaeT: outer membrane protein assembly complex, YaeT protein 71 816 3.0E-222 T 29-03-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 GBCGDNIH2_RS05120 f87cb0d531201905ceebc8a351862926 816 Pfam PF07244 Surface antigen variable number repeat 71 135 6.1E-8 T 29-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 GBCGDNIH2_RS05120 f87cb0d531201905ceebc8a351862926 816 Pfam PF07244 Surface antigen variable number repeat 308 387 9.0E-10 T 29-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 GBCGDNIH2_RS05120 f87cb0d531201905ceebc8a351862926 816 Pfam PF07244 Surface antigen variable number repeat 138 214 4.6E-14 T 29-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 GBCGDNIH2_RS05120 f87cb0d531201905ceebc8a351862926 816 Pfam PF07244 Surface antigen variable number repeat 219 305 1.4E-13 T 29-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 GBCGDNIH2_RS05120 f87cb0d531201905ceebc8a351862926 816 Pfam PF07244 Surface antigen variable number repeat 390 457 1.7E-14 T 29-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 GBCGDNIH2_RS05120 f87cb0d531201905ceebc8a351862926 816 Gene3D G3DSA:2.40.160.50 435 816 7.4E-69 T 29-03-2018 GBCGDNIH2_RS05120 f87cb0d531201905ceebc8a351862926 816 PIRSF PIRSF006076 20 816 5.7E-240 T 29-03-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 GBCGDNIH2_RS05120 f87cb0d531201905ceebc8a351862926 816 Gene3D G3DSA:3.10.20.310 308 389 4.7E-13 T 29-03-2018 GBCGDNIH2_RS05120 f87cb0d531201905ceebc8a351862926 816 Pfam PF01103 Surface antigen 490 816 1.9E-61 T 29-03-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 GBCGDNIH2_RS05120 f87cb0d531201905ceebc8a351862926 816 Gene3D G3DSA:3.10.20.310 67 136 2.0E-13 T 29-03-2018 GBCGDNIH2_RS05120 f87cb0d531201905ceebc8a351862926 816 Gene3D G3DSA:3.10.20.310 137 216 2.2E-17 T 29-03-2018 GBCGDNIH2_RS07750 5f7a13ccc0eb911b32b2b070747de13f 188 Gene3D G3DSA:3.40.50.10610 15 187 1.6E-31 T 29-03-2018 IPR005586 ABC-type transport auxiliary lipoprotein component GBCGDNIH2_RS07750 5f7a13ccc0eb911b32b2b070747de13f 188 SUPERFAMILY SSF159594 24 185 1.2E-19 T 29-03-2018 GBCGDNIH2_RS07750 5f7a13ccc0eb911b32b2b070747de13f 188 Pfam PF03886 ABC-type transport auxiliary lipoprotein component 26 184 1.3E-34 T 29-03-2018 IPR005586 ABC-type transport auxiliary lipoprotein component GBCGDNIH2_RS03330 ca7a399aa8fed008fd84ba91353a71d5 481 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 481 186.02 T 29-03-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 GBCGDNIH2_RS03330 ca7a399aa8fed008fd84ba91353a71d5 481 Gene3D G3DSA:3.40.50.880 250 477 1.7E-16 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like GBCGDNIH2_RS03330 ca7a399aa8fed008fd84ba91353a71d5 481 Gene3D G3DSA:3.40.50.300 1 235 4.5E-42 T 29-03-2018 GBCGDNIH2_RS03330 ca7a399aa8fed008fd84ba91353a71d5 481 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 1 474 6.4E-130 T 29-03-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 GBCGDNIH2_RS03330 ca7a399aa8fed008fd84ba91353a71d5 481 SUPERFAMILY SSF52317 251 443 1.05E-34 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like GBCGDNIH2_RS03330 ca7a399aa8fed008fd84ba91353a71d5 481 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 251 433 9.1E-53 T 29-03-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 GBCGDNIH2_RS03330 ca7a399aa8fed008fd84ba91353a71d5 481 SUPERFAMILY SSF52540 1 234 8.35E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS03330 ca7a399aa8fed008fd84ba91353a71d5 481 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 1 231 3.6E-17 T 29-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain GBCGDNIH2_RS07990 e021d7f81e18b3b8639f58e1331abc30 819 Pfam PF03484 tRNA synthetase B5 domain 406 497 1.9E-9 T 29-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 GBCGDNIH2_RS07990 e021d7f81e18b3b8639f58e1331abc30 819 SUPERFAMILY SSF55681 494 713 3.98E-39 T 29-03-2018 GBCGDNIH2_RS07990 e021d7f81e18b3b8639f58e1331abc30 819 Gene3D G3DSA:3.30.56.10 1 188 4.1E-45 T 29-03-2018 GBCGDNIH2_RS07990 e021d7f81e18b3b8639f58e1331abc30 819 Pfam PF01588 Putative tRNA binding domain 46 147 3.1E-21 T 29-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 GBCGDNIH2_RS07990 e021d7f81e18b3b8639f58e1331abc30 819 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 813 37.983 T 29-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 GBCGDNIH2_RS07990 e021d7f81e18b3b8639f58e1331abc30 819 Gene3D G3DSA:3.30.70.380 723 819 1.8E-18 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 GBCGDNIH2_RS07990 e021d7f81e18b3b8639f58e1331abc30 819 Gene3D G3DSA:3.30.56.10 400 502 4.9E-19 T 29-03-2018 GBCGDNIH2_RS07990 e021d7f81e18b3b8639f58e1331abc30 819 SMART SM00896 726 819 3.2E-35 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 GBCGDNIH2_RS07990 e021d7f81e18b3b8639f58e1331abc30 819 Gene3D G3DSA:3.30.930.10 518 713 1.2E-31 T 29-03-2018 GBCGDNIH2_RS07990 e021d7f81e18b3b8639f58e1331abc30 819 SUPERFAMILY SSF46955 405 457 5.68E-5 T 29-03-2018 IPR009061 Putative DNA-binding domain GBCGDNIH2_RS07990 e021d7f81e18b3b8639f58e1331abc30 819 Gene3D G3DSA:3.50.40.10 197 395 4.7E-69 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 GBCGDNIH2_RS07990 e021d7f81e18b3b8639f58e1331abc30 819 SUPERFAMILY SSF50249 35 197 2.29E-43 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold GBCGDNIH2_RS07990 e021d7f81e18b3b8639f58e1331abc30 819 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 457 4.8E-137 T 29-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 GBCGDNIH2_RS07990 e021d7f81e18b3b8639f58e1331abc30 819 SUPERFAMILY SSF54991 724 819 8.63E-24 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 GBCGDNIH2_RS07990 e021d7f81e18b3b8639f58e1331abc30 819 SMART SM00873 214 386 8.0E-81 T 29-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 GBCGDNIH2_RS07990 e021d7f81e18b3b8639f58e1331abc30 819 Pfam PF03483 B3/4 domain 214 386 5.6E-62 T 29-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 GBCGDNIH2_RS07990 e021d7f81e18b3b8639f58e1331abc30 819 SUPERFAMILY SSF56037 201 394 9.94E-66 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 GBCGDNIH2_RS07990 e021d7f81e18b3b8639f58e1331abc30 819 Pfam PF03147 Ferredoxin-fold anticodon binding domain 727 819 2.7E-20 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 GBCGDNIH2_RS07990 e021d7f81e18b3b8639f58e1331abc30 819 SMART SM00874 402 498 1.6E-11 T 29-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 GBCGDNIH2_RS04015 60ef1bbaf08f6b1ef407021bb4f8b611 358 Gene3D G3DSA:3.30.70.520 77 217 4.1E-63 T 29-03-2018 IPR023447 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, ferredoxin-like domain GBCGDNIH2_RS04015 60ef1bbaf08f6b1ef407021bb4f8b611 358 Pfam PF01913 Formylmethanofuran-tetrahydromethanopterin formyltransferase 61 202 3.5E-60 T 29-03-2018 IPR022667 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, N-terminal GO:0006730|GO:0016740 GBCGDNIH2_RS04015 60ef1bbaf08f6b1ef407021bb4f8b611 358 Gene3D G3DSA:3.30.70.520 218 356 1.2E-57 T 29-03-2018 IPR023447 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, ferredoxin-like domain GBCGDNIH2_RS04015 60ef1bbaf08f6b1ef407021bb4f8b611 358 SUPERFAMILY SSF55112 61 203 8.89E-62 T 29-03-2018 IPR023447 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, ferredoxin-like domain GBCGDNIH2_RS04015 60ef1bbaf08f6b1ef407021bb4f8b611 358 TIGRFAM TIGR03119 one_C_fhcD: formylmethanofuran--tetrahydromethanopterin N-formyltransferase 66 356 1.8E-130 T 29-03-2018 IPR014053 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr GO:0006730|GO:0030270 GBCGDNIH2_RS04015 60ef1bbaf08f6b1ef407021bb4f8b611 358 Hamap MF_00579 Formylmethanofuran--tetrahydromethanopterin formyltransferase [ftr]. 59 357 45.004 T 29-03-2018 IPR014053 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr GO:0006730|GO:0030270 GBCGDNIH2_RS04015 60ef1bbaf08f6b1ef407021bb4f8b611 358 Pfam PF02741 FTR, proximal lobe 205 356 1.7E-62 T 29-03-2018 IPR002770 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, C-terminal GO:0006730|GO:0016740 GBCGDNIH2_RS04015 60ef1bbaf08f6b1ef407021bb4f8b611 358 SUPERFAMILY SSF55112 204 357 1.46E-57 T 29-03-2018 IPR023447 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, ferredoxin-like domain GBCGDNIH2_RS02310 a62f4128aeec8110d61602e4f7b35397 240 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 238 3.7E-59 T 29-03-2018 GBCGDNIH2_RS02310 a62f4128aeec8110d61602e4f7b35397 240 TIGRFAM TIGR01829 AcAcCoA_reduct: acetoacetyl-CoA reductase 3 239 2.8E-98 T 29-03-2018 IPR011283 Acetoacetyl-CoA reductase GO:0005737|GO:0018454|GO:0042619|GO:0055114 KEGG: 00630+1.1.1.36|KEGG: 00650+1.1.1.36|MetaCyc: PWY-5676|MetaCyc: PWY-5741|MetaCyc: PWY-7216 GBCGDNIH2_RS02310 a62f4128aeec8110d61602e4f7b35397 240 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 178 3.1E-6 T 29-03-2018 GBCGDNIH2_RS02310 a62f4128aeec8110d61602e4f7b35397 240 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 134 162 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 GBCGDNIH2_RS02310 a62f4128aeec8110d61602e4f7b35397 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 1.5E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS02310 a62f4128aeec8110d61602e4f7b35397 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 1.5E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS02310 a62f4128aeec8110d61602e4f7b35397 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 201 221 1.5E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS02310 a62f4128aeec8110d61602e4f7b35397 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.5E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS02310 a62f4128aeec8110d61602e4f7b35397 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 1.5E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS02310 a62f4128aeec8110d61602e4f7b35397 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 1.5E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS02310 a62f4128aeec8110d61602e4f7b35397 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 2.6E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS02310 a62f4128aeec8110d61602e4f7b35397 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 135 2.6E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS02310 a62f4128aeec8110d61602e4f7b35397 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 166 2.6E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS02310 a62f4128aeec8110d61602e4f7b35397 240 Gene3D G3DSA:3.40.50.720 39 240 6.5E-64 T 29-03-2018 GBCGDNIH2_RS02310 a62f4128aeec8110d61602e4f7b35397 240 Gene3D G3DSA:3.40.50.720 1 38 1.5E-5 T 29-03-2018 GBCGDNIH2_RS02310 a62f4128aeec8110d61602e4f7b35397 240 SUPERFAMILY SSF51735 3 239 8.18E-78 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS11160 e8054c26354815823eb608859d711d78 236 Pfam PF05239 PRC-barrel domain 98 151 3.4E-10 T 29-03-2018 IPR027275 PRC-barrel domain GBCGDNIH2_RS11160 e8054c26354815823eb608859d711d78 236 SUPERFAMILY SSF50346 73 178 5.49E-13 T 29-03-2018 IPR011033 PRC-barrel-like GBCGDNIH2_RS11160 e8054c26354815823eb608859d711d78 236 Gene3D G3DSA:3.90.50.10 22 203 6.4E-23 T 29-03-2018 GBCGDNIH2_RS09935 85861fbf33637ffe31003172a64356e7 233 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 86 106 - T 29-03-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 GBCGDNIH2_RS09935 85861fbf33637ffe31003172a64356e7 233 Pfam PF00484 Carbonic anhydrase 35 194 8.8E-50 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 GBCGDNIH2_RS09935 85861fbf33637ffe31003172a64356e7 233 SUPERFAMILY SSF53056 2 211 2.35E-63 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 GBCGDNIH2_RS09935 85861fbf33637ffe31003172a64356e7 233 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 40 47 - T 29-03-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 GBCGDNIH2_RS09935 85861fbf33637ffe31003172a64356e7 233 Gene3D G3DSA:3.40.1050.10 1 227 5.4E-68 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 GBCGDNIH2_RS09935 85861fbf33637ffe31003172a64356e7 233 SMART SM00947 28 199 3.3E-65 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 GBCGDNIH2_RS03080 3fbd30799b7debb392e4ab5b6c1e0e75 804 Pfam PF00391 PEP-utilising enzyme, mobile domain 383 456 4.9E-14 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 GBCGDNIH2_RS03080 3fbd30799b7debb392e4ab5b6c1e0e75 804 SUPERFAMILY SSF55781 53 196 1.48E-25 T 29-03-2018 IPR029016 GAF domain-like GBCGDNIH2_RS03080 3fbd30799b7debb392e4ab5b6c1e0e75 804 Gene3D G3DSA:3.30.450.40 50 204 3.3E-24 T 29-03-2018 IPR029016 GAF domain-like GBCGDNIH2_RS03080 3fbd30799b7debb392e4ab5b6c1e0e75 804 Pfam PF13185 GAF domain 66 197 3.7E-14 T 29-03-2018 IPR003018 GAF domain GO:0005515 GBCGDNIH2_RS03080 3fbd30799b7debb392e4ab5b6c1e0e75 804 Gene3D G3DSA:3.50.30.10 378 472 3.7E-14 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 GBCGDNIH2_RS03080 3fbd30799b7debb392e4ab5b6c1e0e75 804 Gene3D G3DSA:1.10.274.10 240 377 3.0E-37 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 GBCGDNIH2_RS03080 3fbd30799b7debb392e4ab5b6c1e0e75 804 Gene3D G3DSA:3.20.20.60 481 791 2.7E-73 T 29-03-2018 GBCGDNIH2_RS03080 3fbd30799b7debb392e4ab5b6c1e0e75 804 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 674 692 - T 29-03-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 GBCGDNIH2_RS03080 3fbd30799b7debb392e4ab5b6c1e0e75 804 SUPERFAMILY SSF51621 483 772 2.12E-77 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 GBCGDNIH2_RS03080 3fbd30799b7debb392e4ab5b6c1e0e75 804 SMART SM00065 63 209 4.3E-15 T 29-03-2018 IPR003018 GAF domain GO:0005515 GBCGDNIH2_RS03080 3fbd30799b7debb392e4ab5b6c1e0e75 804 SUPERFAMILY SSF47831 241 377 2.09E-19 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 GBCGDNIH2_RS03080 3fbd30799b7debb392e4ab5b6c1e0e75 804 SUPERFAMILY SSF52009 359 470 4.06E-22 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 GBCGDNIH2_RS03080 3fbd30799b7debb392e4ab5b6c1e0e75 804 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 483 765 3.7E-73 T 29-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 GBCGDNIH2_RS03080 3fbd30799b7debb392e4ab5b6c1e0e75 804 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 524 543 1.4E-11 T 29-03-2018 GBCGDNIH2_RS03080 3fbd30799b7debb392e4ab5b6c1e0e75 804 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 674 689 1.4E-11 T 29-03-2018 GBCGDNIH2_RS03080 3fbd30799b7debb392e4ab5b6c1e0e75 804 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 691 706 1.4E-11 T 29-03-2018 GBCGDNIH2_RS03080 3fbd30799b7debb392e4ab5b6c1e0e75 804 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 727 739 1.4E-11 T 29-03-2018 GBCGDNIH2_RS03080 3fbd30799b7debb392e4ab5b6c1e0e75 804 Pfam PF05524 PEP-utilising enzyme, N-terminal 221 360 3.3E-21 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 GBCGDNIH2_RS03065 5e4694f9ef89680a57496cc732b82f21 251 Gene3D G3DSA:3.40.50.150 3 250 1.1E-46 T 29-03-2018 GBCGDNIH2_RS03065 5e4694f9ef89680a57496cc732b82f21 251 TIGRFAM TIGR01983 UbiG: 3-demethylubiquinone-9 3-O-methyltransferase 23 244 8.6E-72 T 29-03-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|KEGG: 00340+2.1.1.22|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 GBCGDNIH2_RS03065 5e4694f9ef89680a57496cc732b82f21 251 SUPERFAMILY SSF53335 34 234 2.74E-44 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GBCGDNIH2_RS03065 5e4694f9ef89680a57496cc732b82f21 251 Pfam PF13489 Methyltransferase domain 66 218 1.6E-21 T 29-03-2018 GBCGDNIH2_RS03065 5e4694f9ef89680a57496cc732b82f21 251 Hamap MF_00472 Ubiquinone biosynthesis O-methyltransferase [ubiG]. 21 250 36.661 T 29-03-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|KEGG: 00340+2.1.1.22|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 GBCGDNIH2_RS10815 fdabf77daff08212d7e1389092c650eb 260 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 32 252 3.7E-79 T 29-03-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 GBCGDNIH2_RS10815 fdabf77daff08212d7e1389092c650eb 260 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 80 88 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 GBCGDNIH2_RS10815 fdabf77daff08212d7e1389092c650eb 260 Gene3D G3DSA:3.10.20.30 21 126 2.0E-34 T 29-03-2018 IPR012675 Beta-grasp domain GBCGDNIH2_RS10815 fdabf77daff08212d7e1389092c650eb 260 Pfam PF13534 4Fe-4S dicluster domain 170 243 7.1E-10 T 29-03-2018 GBCGDNIH2_RS10815 fdabf77daff08212d7e1389092c650eb 260 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 30 132 8.1E-32 T 29-03-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 GBCGDNIH2_RS10815 fdabf77daff08212d7e1389092c650eb 260 SUPERFAMILY SSF46548 130 257 1.45E-37 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 GBCGDNIH2_RS10815 fdabf77daff08212d7e1389092c650eb 260 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 171 182 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site GBCGDNIH2_RS10815 fdabf77daff08212d7e1389092c650eb 260 Gene3D G3DSA:1.10.1060.10 129 260 5.6E-30 T 29-03-2018 GBCGDNIH2_RS10815 fdabf77daff08212d7e1389092c650eb 260 SUPERFAMILY SSF54292 26 128 1.89E-30 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 GBCGDNIH2_RS10125 600c9923ecef0d16af176082905217c3 712 Pfam PF07715 TonB-dependent Receptor Plug Domain 73 174 7.1E-20 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 GBCGDNIH2_RS10125 600c9923ecef0d16af176082905217c3 712 Gene3D G3DSA:2.40.170.20 187 712 1.1E-68 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 GBCGDNIH2_RS10125 600c9923ecef0d16af176082905217c3 712 Pfam PF00593 TonB dependent receptor 278 711 3.4E-52 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 GBCGDNIH2_RS10125 600c9923ecef0d16af176082905217c3 712 SUPERFAMILY SSF56935 33 712 4.88E-118 T 29-03-2018 GBCGDNIH2_RS10125 600c9923ecef0d16af176082905217c3 712 Gene3D G3DSA:2.170.130.10 30 181 4.9E-25 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 GBCGDNIH2_RS10125 600c9923ecef0d16af176082905217c3 712 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 76 710 1.1E-102 T 29-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 GBCGDNIH2_RS10620 7c13c7294b403a9366eb54e068109c2d 396 Pfam PF02769 AIR synthase related protein, C-terminal domain 223 384 4.0E-34 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain GBCGDNIH2_RS10620 7c13c7294b403a9366eb54e068109c2d 396 SUPERFAMILY SSF55326 53 216 6.28E-50 T 29-03-2018 IPR016188 PurM-like, N-terminal domain GBCGDNIH2_RS10620 7c13c7294b403a9366eb54e068109c2d 396 SUPERFAMILY SSF56042 219 384 5.98E-56 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain GBCGDNIH2_RS10620 7c13c7294b403a9366eb54e068109c2d 396 Gene3D G3DSA:3.30.1330.10 81 208 3.0E-53 T 29-03-2018 IPR016188 PurM-like, N-terminal domain GBCGDNIH2_RS10620 7c13c7294b403a9366eb54e068109c2d 396 Gene3D G3DSA:3.90.650.10 218 389 2.0E-56 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain GBCGDNIH2_RS10620 7c13c7294b403a9366eb54e068109c2d 396 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 53 380 3.5E-130 T 29-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 GBCGDNIH2_RS10620 7c13c7294b403a9366eb54e068109c2d 396 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 53 391 43.796 T 29-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 GBCGDNIH2_RS10620 7c13c7294b403a9366eb54e068109c2d 396 Pfam PF00586 AIR synthase related protein, N-terminal domain 107 204 4.8E-14 T 29-03-2018 IPR016188 PurM-like, N-terminal domain GBCGDNIH2_RS10445 9bcae32acd78a18db509d9fcaf229526 275 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 9 266 9.2E-17 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase GBCGDNIH2_RS10445 9bcae32acd78a18db509d9fcaf229526 275 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 7 273 4.7E-53 T 29-03-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 GBCGDNIH2_RS10445 9bcae32acd78a18db509d9fcaf229526 275 SUPERFAMILY SSF56219 7 274 1.44E-67 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase GBCGDNIH2_RS10445 9bcae32acd78a18db509d9fcaf229526 275 Gene3D G3DSA:3.60.10.10 3 275 4.8E-48 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase GBCGDNIH2_RS10445 9bcae32acd78a18db509d9fcaf229526 275 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 32 41 - T 29-03-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 GBCGDNIH2_RS11930 7b8b77ac10790048a057d9602ba80a80 120 SUPERFAMILY SSF55620 3 114 8.89E-30 T 29-03-2018 GBCGDNIH2_RS11930 7b8b77ac10790048a057d9602ba80a80 120 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 3 118 3.1E-28 T 29-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 GBCGDNIH2_RS11930 7b8b77ac10790048a057d9602ba80a80 120 PIRSF PIRSF006113 1 119 2.4E-25 T 29-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 GBCGDNIH2_RS11930 7b8b77ac10790048a057d9602ba80a80 120 Gene3D G3DSA:3.30.479.10 1 119 3.0E-31 T 29-03-2018 GBCGDNIH2_RS02365 5e6994fea83df4fa4976f6ebb244e057 188 SUPERFAMILY SSF53335 1 165 3.49E-42 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GBCGDNIH2_RS02365 5e6994fea83df4fa4976f6ebb244e057 188 Pfam PF03602 Conserved hypothetical protein 95 1 180 3.7E-47 T 29-03-2018 GBCGDNIH2_RS02365 5e6994fea83df4fa4976f6ebb244e057 188 Gene3D G3DSA:3.40.50.150 1 185 8.3E-32 T 29-03-2018 GBCGDNIH2_RS02365 5e6994fea83df4fa4976f6ebb244e057 188 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 2 179 5.1E-40 T 29-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 GBCGDNIH2_RS02365 5e6994fea83df4fa4976f6ebb244e057 188 PIRSF PIRSF004553 1 185 1.2E-44 T 29-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 GBCGDNIH2_RS01395 e77f8130a112926bbb3b5c1147284ad0 118 Gene3D G3DSA:2.102.10.10 2 117 8.0E-20 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 GBCGDNIH2_RS01395 e77f8130a112926bbb3b5c1147284ad0 118 Pfam PF00355 Rieske [2Fe-2S] domain 35 96 5.0E-9 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 GBCGDNIH2_RS01395 e77f8130a112926bbb3b5c1147284ad0 118 SUPERFAMILY SSF50022 8 114 5.5E-23 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 GBCGDNIH2_RS10840 1bd0e5cd863f881f3a87e5d53125fce2 177 Gene3D G3DSA:1.10.10.10 4 150 1.1E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS10840 1bd0e5cd863f881f3a87e5d53125fce2 177 SUPERFAMILY SSF46785 3 147 1.23E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS10840 1bd0e5cd863f881f3a87e5d53125fce2 177 Pfam PF01047 MarR family 40 96 9.0E-19 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GBCGDNIH2_RS10840 1bd0e5cd863f881f3a87e5d53125fce2 177 SMART SM00347 32 132 3.9E-21 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GBCGDNIH2_RS10840 1bd0e5cd863f881f3a87e5d53125fce2 177 PRINTS PR00598 Bacterial regulatory protein MarR family signature 92 108 3.3E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GBCGDNIH2_RS10840 1bd0e5cd863f881f3a87e5d53125fce2 177 PRINTS PR00598 Bacterial regulatory protein MarR family signature 56 72 3.3E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GBCGDNIH2_RS10840 1bd0e5cd863f881f3a87e5d53125fce2 177 PRINTS PR00598 Bacterial regulatory protein MarR family signature 73 88 3.3E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GBCGDNIH2_RS00085 be4c2a8bcda85905ac777c2ba96f0324 68 Gene3D G3DSA:2.40.50.140 1 67 2.3E-22 T 29-03-2018 GBCGDNIH2_RS00085 be4c2a8bcda85905ac777c2ba96f0324 68 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 1.6E-23 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 GBCGDNIH2_RS00085 be4c2a8bcda85905ac777c2ba96f0324 68 PIRSF PIRSF002599 1 68 1.5E-21 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 GBCGDNIH2_RS00085 be4c2a8bcda85905ac777c2ba96f0324 68 SMART SM00357 3 68 6.8E-25 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 GBCGDNIH2_RS00085 be4c2a8bcda85905ac777c2ba96f0324 68 PRINTS PR00050 Cold shock protein signature 25 34 5.1E-15 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 GBCGDNIH2_RS00085 be4c2a8bcda85905ac777c2ba96f0324 68 PRINTS PR00050 Cold shock protein signature 4 19 5.1E-15 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 GBCGDNIH2_RS00085 be4c2a8bcda85905ac777c2ba96f0324 68 PRINTS PR00050 Cold shock protein signature 40 58 5.1E-15 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 GBCGDNIH2_RS00085 be4c2a8bcda85905ac777c2ba96f0324 68 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 29-03-2018 IPR019844 Cold-shock conserved site GBCGDNIH2_RS00085 be4c2a8bcda85905ac777c2ba96f0324 68 SUPERFAMILY SSF50249 1 66 2.79E-21 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold GBCGDNIH2_RS08645 8d5e7004cf4f01b8a7893bd3382db267 147 Pfam PF03073 TspO/MBR family 6 145 3.8E-44 T 29-03-2018 IPR004307 TspO/MBR-related protein GO:0016021 GBCGDNIH2_RS08645 8d5e7004cf4f01b8a7893bd3382db267 147 PIRSF PIRSF005859 1 147 3.4E-40 T 29-03-2018 IPR004307 TspO/MBR-related protein GO:0016021 GBCGDNIH2_RS04625 61da605f8e936645b4692dea25b9e1c9 855 Gene3D G3DSA:3.40.50.300 238 372 1.7E-22 T 29-03-2018 GBCGDNIH2_RS04625 61da605f8e936645b4692dea25b9e1c9 855 Gene3D G3DSA:3.40.50.300 3 206 1.7E-31 T 29-03-2018 GBCGDNIH2_RS04625 61da605f8e936645b4692dea25b9e1c9 855 TIGRFAM TIGR04121 DEXH_lig_assoc: DEXH box helicase, DNA ligase-associated 9 807 0.0 T 29-03-2018 IPR026362 DEXH box helicase, DNA ligase-associated GBCGDNIH2_RS04625 61da605f8e936645b4692dea25b9e1c9 855 SMART SM00490 269 351 3.5E-13 T 29-03-2018 IPR001650 Helicase, C-terminal GBCGDNIH2_RS04625 61da605f8e936645b4692dea25b9e1c9 855 SMART SM00487 17 225 2.2E-28 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain GBCGDNIH2_RS04625 61da605f8e936645b4692dea25b9e1c9 855 SUPERFAMILY SSF52540 30 358 8.8E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS04625 61da605f8e936645b4692dea25b9e1c9 855 PIRSF PIRSF037307 2 823 1.9E-181 T 29-03-2018 IPR017170 Lhr-like ATP-dependent RNA helicase, predicted GO:0005524|GO:0016818 GBCGDNIH2_RS04625 61da605f8e936645b4692dea25b9e1c9 855 Pfam PF08494 DEAD/H associated 598 779 1.3E-43 T 29-03-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 GBCGDNIH2_RS04625 61da605f8e936645b4692dea25b9e1c9 855 Pfam PF00271 Helicase conserved C-terminal domain 246 346 5.7E-14 T 29-03-2018 IPR001650 Helicase, C-terminal GBCGDNIH2_RS04625 61da605f8e936645b4692dea25b9e1c9 855 Pfam PF00270 DEAD/DEAH box helicase 23 196 2.8E-22 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 GBCGDNIH2_RS00060 9c51648046a9da193dea3ebe768ad2b7 440 Pfam PF10396 GTP-binding protein TrmE N-terminus 5 118 8.5E-36 T 29-03-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 GBCGDNIH2_RS00060 9c51648046a9da193dea3ebe768ad2b7 440 Pfam PF01926 50S ribosome-binding GTPase 218 316 4.4E-21 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 GBCGDNIH2_RS00060 9c51648046a9da193dea3ebe768ad2b7 440 SUPERFAMILY SSF52540 186 361 2.39E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS00060 9c51648046a9da193dea3ebe768ad2b7 440 SUPERFAMILY SSF52540 71 150 2.39E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS00060 9c51648046a9da193dea3ebe768ad2b7 440 Gene3D G3DSA:1.20.120.430 278 440 5.1E-26 T 29-03-2018 GBCGDNIH2_RS00060 9c51648046a9da193dea3ebe768ad2b7 440 Gene3D G3DSA:1.20.120.430 120 277 1.8E-22 T 29-03-2018 GBCGDNIH2_RS00060 9c51648046a9da193dea3ebe768ad2b7 440 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 14 440 1.3E-88 T 29-03-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 GBCGDNIH2_RS00060 9c51648046a9da193dea3ebe768ad2b7 440 Pfam PF12631 MnmE helical domain 121 437 1.8E-48 T 29-03-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 GBCGDNIH2_RS00060 9c51648046a9da193dea3ebe768ad2b7 440 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 218 334 7.1E-18 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 GBCGDNIH2_RS00060 9c51648046a9da193dea3ebe768ad2b7 440 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 4 440 30.651 T 29-03-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 GBCGDNIH2_RS00060 9c51648046a9da193dea3ebe768ad2b7 440 Gene3D G3DSA:3.30.1360.120 1 119 2.2E-41 T 29-03-2018 GBCGDNIH2_RS02230 d159e25ba91da8d56158eb56c642150a 459 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 1 448 30.198 T 29-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GBCGDNIH2_RS02230 d159e25ba91da8d56158eb56c642150a 459 Gene3D G3DSA:3.90.190.20 309 458 1.6E-31 T 29-03-2018 GBCGDNIH2_RS02230 d159e25ba91da8d56158eb56c642150a 459 Pfam PF01225 Mur ligase family, catalytic domain 25 71 1.9E-10 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 GBCGDNIH2_RS02230 d159e25ba91da8d56158eb56c642150a 459 Pfam PF02875 Mur ligase family, glutamate ligase domain 325 391 3.2E-8 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 GBCGDNIH2_RS02230 d159e25ba91da8d56158eb56c642150a 459 SUPERFAMILY SSF53244 323 446 7.02E-27 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 GBCGDNIH2_RS02230 d159e25ba91da8d56158eb56c642150a 459 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 29 447 1.7E-109 T 29-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GBCGDNIH2_RS02230 d159e25ba91da8d56158eb56c642150a 459 SUPERFAMILY SSF53623 99 308 2.09E-52 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 GBCGDNIH2_RS02230 d159e25ba91da8d56158eb56c642150a 459 Gene3D G3DSA:3.40.1390.10 10 87 4.3E-20 T 29-03-2018 GBCGDNIH2_RS02230 d159e25ba91da8d56158eb56c642150a 459 Gene3D G3DSA:3.40.1190.10 88 308 2.1E-54 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 GBCGDNIH2_RS02230 d159e25ba91da8d56158eb56c642150a 459 Pfam PF08245 Mur ligase middle domain 103 290 2.3E-44 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 GBCGDNIH2_RS02230 d159e25ba91da8d56158eb56c642150a 459 SUPERFAMILY SSF63418 8 95 2.62E-19 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 GBCGDNIH2_RS07185 d165a85dae27fe9849de1a3445c60f46 693 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 50 65 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site GBCGDNIH2_RS07185 d165a85dae27fe9849de1a3445c60f46 693 SMART SM00889 481 599 3.8E-66 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 GBCGDNIH2_RS07185 d165a85dae27fe9849de1a3445c60f46 693 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 179 5.1E-29 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 GBCGDNIH2_RS07185 d165a85dae27fe9849de1a3445c60f46 693 Gene3D G3DSA:3.40.50.300 2 286 2.7E-53 T 29-03-2018 GBCGDNIH2_RS07185 d165a85dae27fe9849de1a3445c60f46 693 Gene3D G3DSA:3.30.230.10 493 614 2.2E-42 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup GBCGDNIH2_RS07185 d165a85dae27fe9849de1a3445c60f46 693 Pfam PF14492 Elongation Factor G, domain II 405 478 9.1E-30 T 29-03-2018 GBCGDNIH2_RS07185 d165a85dae27fe9849de1a3445c60f46 693 Gene3D G3DSA:3.30.70.240 615 692 2.4E-33 T 29-03-2018 GBCGDNIH2_RS07185 d165a85dae27fe9849de1a3445c60f46 693 SUPERFAMILY SSF54980 405 482 1.22E-22 T 29-03-2018 IPR035647 EF-G domain III/V-like GBCGDNIH2_RS07185 d165a85dae27fe9849de1a3445c60f46 693 SUPERFAMILY SSF52540 5 279 3.91E-104 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS07185 d165a85dae27fe9849de1a3445c60f46 693 Hamap MF_00054_B Elongation factor G [fusA]. 5 692 105.957 T 29-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 GBCGDNIH2_RS07185 d165a85dae27fe9849de1a3445c60f46 693 PRINTS PR00315 GTP-binding elongation factor signature 93 104 2.7E-16 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GBCGDNIH2_RS07185 d165a85dae27fe9849de1a3445c60f46 693 PRINTS PR00315 GTP-binding elongation factor signature 11 24 2.7E-16 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GBCGDNIH2_RS07185 d165a85dae27fe9849de1a3445c60f46 693 PRINTS PR00315 GTP-binding elongation factor signature 129 138 2.7E-16 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GBCGDNIH2_RS07185 d165a85dae27fe9849de1a3445c60f46 693 PRINTS PR00315 GTP-binding elongation factor signature 77 87 2.7E-16 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GBCGDNIH2_RS07185 d165a85dae27fe9849de1a3445c60f46 693 PRINTS PR00315 GTP-binding elongation factor signature 57 65 2.7E-16 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GBCGDNIH2_RS07185 d165a85dae27fe9849de1a3445c60f46 693 Gene3D G3DSA:3.30.70.870 401 492 1.3E-32 T 29-03-2018 GBCGDNIH2_RS07185 d165a85dae27fe9849de1a3445c60f46 693 Pfam PF00679 Elongation factor G C-terminus 602 687 2.8E-31 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like GBCGDNIH2_RS07185 d165a85dae27fe9849de1a3445c60f46 693 SUPERFAMILY SSF50447 263 405 2.14E-33 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain GBCGDNIH2_RS07185 d165a85dae27fe9849de1a3445c60f46 693 SUPERFAMILY SSF54980 604 691 1.08E-30 T 29-03-2018 IPR035647 EF-G domain III/V-like GBCGDNIH2_RS07185 d165a85dae27fe9849de1a3445c60f46 693 SUPERFAMILY SSF54211 480 600 3.54E-42 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold GBCGDNIH2_RS07185 d165a85dae27fe9849de1a3445c60f46 693 TIGRFAM TIGR00484 EF-G: translation elongation factor G 5 691 0.0 T 29-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 GBCGDNIH2_RS07185 d165a85dae27fe9849de1a3445c60f46 693 Pfam PF03144 Elongation factor Tu domain 2 325 392 3.2E-16 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 GBCGDNIH2_RS07185 d165a85dae27fe9849de1a3445c60f46 693 Pfam PF00009 Elongation factor Tu GTP binding domain 8 279 1.2E-64 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GBCGDNIH2_RS07185 d165a85dae27fe9849de1a3445c60f46 693 Gene3D G3DSA:2.40.30.10 289 400 1.7E-29 T 29-03-2018 GBCGDNIH2_RS07185 d165a85dae27fe9849de1a3445c60f46 693 Pfam PF03764 Elongation factor G, domain IV 480 598 5.6E-44 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 GBCGDNIH2_RS07185 d165a85dae27fe9849de1a3445c60f46 693 SMART SM00838 601 688 2.0E-51 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like GBCGDNIH2_RS02675 13c17772dc5ce567adc6e79613cd63ef 468 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 11 150 5.7E-31 T 29-03-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS02675 13c17772dc5ce567adc6e79613cd63ef 468 Gene3D G3DSA:3.40.50.720 3 163 8.5E-26 T 29-03-2018 GBCGDNIH2_RS02675 13c17772dc5ce567adc6e79613cd63ef 468 Pfam PF16653 Saccharopine dehydrogenase C-terminal domain 154 435 1.1E-27 T 29-03-2018 IPR032095 Saccharopine dehydrogenase, C-terminal Reactome: R-HSA-71064 GBCGDNIH2_RS02675 13c17772dc5ce567adc6e79613cd63ef 468 Gene3D G3DSA:3.30.360.30 164 468 8.6E-147 T 29-03-2018 IPR023181 Homospermidine synthase-like, domain KEGG: 00960+2.5.1.44 GBCGDNIH2_RS00930 b81bfc08b633bff1b482bd89ab2e09fe 899 SUPERFAMILY SSF55874 730 894 1.44E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS00930 b81bfc08b633bff1b482bd89ab2e09fe 899 SMART SM00387 784 896 2.6E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS00930 b81bfc08b633bff1b482bd89ab2e09fe 899 Gene3D G3DSA:1.20.120.620 408 507 2.3E-25 T 29-03-2018 GBCGDNIH2_RS00930 b81bfc08b633bff1b482bd89ab2e09fe 899 Pfam PF13493 Domain of unknown function (DUF4118) 409 515 8.8E-27 T 29-03-2018 IPR025201 Sensor protein KdpD, transmembrane domain GBCGDNIH2_RS00930 b81bfc08b633bff1b482bd89ab2e09fe 899 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 26 235 1.4E-96 T 29-03-2018 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 GBCGDNIH2_RS00930 b81bfc08b633bff1b482bd89ab2e09fe 899 Pfam PF00512 His Kinase A (phospho-acceptor) domain 673 740 8.9E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GBCGDNIH2_RS00930 b81bfc08b633bff1b482bd89ab2e09fe 899 SMART SM00388 672 740 7.8E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GBCGDNIH2_RS00930 b81bfc08b633bff1b482bd89ab2e09fe 899 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 786 895 1.8E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS00930 b81bfc08b633bff1b482bd89ab2e09fe 899 Gene3D G3DSA:3.40.50.300 26 154 9.1E-20 T 29-03-2018 GBCGDNIH2_RS00930 b81bfc08b633bff1b482bd89ab2e09fe 899 SUPERFAMILY SSF55781 515 656 9.38E-9 T 29-03-2018 IPR029016 GAF domain-like GBCGDNIH2_RS00930 b81bfc08b633bff1b482bd89ab2e09fe 899 SUPERFAMILY SSF47384 667 740 1.75E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GBCGDNIH2_RS00930 b81bfc08b633bff1b482bd89ab2e09fe 899 Gene3D G3DSA:3.40.50.620 232 385 4.0E-7 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GBCGDNIH2_RS00930 b81bfc08b633bff1b482bd89ab2e09fe 899 Pfam PF13492 GAF domain 535 653 8.5E-12 T 29-03-2018 IPR003018 GAF domain GO:0005515 GBCGDNIH2_RS00930 b81bfc08b633bff1b482bd89ab2e09fe 899 Gene3D G3DSA:1.10.287.130 665 725 6.4E-15 T 29-03-2018 GBCGDNIH2_RS00930 b81bfc08b633bff1b482bd89ab2e09fe 899 PRINTS PR00344 Bacterial sensor protein C-terminal signature 855 873 2.0E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS00930 b81bfc08b633bff1b482bd89ab2e09fe 899 PRINTS PR00344 Bacterial sensor protein C-terminal signature 839 849 2.0E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS00930 b81bfc08b633bff1b482bd89ab2e09fe 899 PRINTS PR00344 Bacterial sensor protein C-terminal signature 821 835 2.0E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS00930 b81bfc08b633bff1b482bd89ab2e09fe 899 PRINTS PR00344 Bacterial sensor protein C-terminal signature 880 893 2.0E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS00930 b81bfc08b633bff1b482bd89ab2e09fe 899 Gene3D G3DSA:3.30.565.10 726 896 7.2E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS00930 b81bfc08b633bff1b482bd89ab2e09fe 899 Gene3D G3DSA:3.30.450.40 508 664 2.1E-10 T 29-03-2018 IPR029016 GAF domain-like GBCGDNIH2_RS02430 b499f4f470fdc5221fa6260df75de6e5 591 Gene3D G3DSA:1.20.58.220 368 485 7.0E-10 T 29-03-2018 GBCGDNIH2_RS02430 b499f4f470fdc5221fa6260df75de6e5 591 Pfam PF02690 Na+/Pi-cotransporter 202 301 6.7E-13 T 29-03-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 GBCGDNIH2_RS02430 b499f4f470fdc5221fa6260df75de6e5 591 Pfam PF02690 Na+/Pi-cotransporter 58 190 8.0E-37 T 29-03-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 GBCGDNIH2_RS02430 b499f4f470fdc5221fa6260df75de6e5 591 Gene3D G3DSA:1.20.58.220 486 576 1.9E-7 T 29-03-2018 GBCGDNIH2_RS02430 b499f4f470fdc5221fa6260df75de6e5 591 Pfam PF01895 PhoU domain 386 465 3.3E-5 T 29-03-2018 IPR026022 PhoU domain GBCGDNIH2_RS02430 b499f4f470fdc5221fa6260df75de6e5 591 SUPERFAMILY SSF109755 365 574 2.41E-24 T 29-03-2018 GBCGDNIH2_RS02430 b499f4f470fdc5221fa6260df75de6e5 591 TIGRFAM TIGR00704 NaPi_cotrn_rel: Na/Pi-cotransporter II-related protein 48 353 2.2E-73 T 29-03-2018 IPR004633 Na/Pi-cotransporter II-related/YqeW-like protein GO:0016020 GBCGDNIH2_RS10790 0d91072c4e55278a312ed6515b7ad45c 379 Gene3D G3DSA:3.40.50.300 27 376 4.0E-10 T 29-03-2018 GBCGDNIH2_RS10790 0d91072c4e55278a312ed6515b7ad45c 379 Pfam PF03969 AFG1-like ATPase 13 374 5.4E-115 T 29-03-2018 IPR005654 ATPase, AFG1-like GO:0005524 GBCGDNIH2_RS10790 0d91072c4e55278a312ed6515b7ad45c 379 SUPERFAMILY SSF52540 61 190 1.78E-11 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS09260 85058df1e5456f9ddb3fcd5cf6b17510 156 Pfam PF07963 Prokaryotic N-terminal methylation motif 21 43 3.1E-8 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site GBCGDNIH2_RS09260 85058df1e5456f9ddb3fcd5cf6b17510 156 TIGRFAM TIGR01710 typeII_sec_gspG: type II secretion system protein G 23 145 2.6E-36 T 29-03-2018 IPR010054 General secretion pathway protein G GO:0008565|GO:0015627|GO:0015628 GBCGDNIH2_RS09260 85058df1e5456f9ddb3fcd5cf6b17510 156 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 22 42 - T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site GBCGDNIH2_RS09260 85058df1e5456f9ddb3fcd5cf6b17510 156 SUPERFAMILY SSF54523 50 146 1.57E-23 T 29-03-2018 GBCGDNIH2_RS09260 85058df1e5456f9ddb3fcd5cf6b17510 156 Pfam PF08334 Type II secretion system (T2SS), protein G 47 155 1.5E-31 T 29-03-2018 IPR013545 Type II secretion system protein G GBCGDNIH2_RS09260 85058df1e5456f9ddb3fcd5cf6b17510 156 Gene3D G3DSA:3.30.700.10 37 149 8.7E-22 T 29-03-2018 GBCGDNIH2_RS09260 85058df1e5456f9ddb3fcd5cf6b17510 156 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 22 44 4.5E-9 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site GBCGDNIH2_RS09260 85058df1e5456f9ddb3fcd5cf6b17510 156 PRINTS PR00813 Bacterial general secretion pathway protein G signature 23 48 4.1E-13 T 29-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 GBCGDNIH2_RS09260 85058df1e5456f9ddb3fcd5cf6b17510 156 PRINTS PR00813 Bacterial general secretion pathway protein G signature 59 77 4.1E-13 T 29-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 GBCGDNIH2_RS02395 08190c149fd3614b8a6c712c92973c69 941 SUPERFAMILY SSF50677 211 411 1.78E-51 T 29-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 GBCGDNIH2_RS02395 08190c149fd3614b8a6c712c92973c69 941 SUPERFAMILY SSF47323 660 933 1.16E-56 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 GBCGDNIH2_RS02395 08190c149fd3614b8a6c712c92973c69 941 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 536 549 6.2E-30 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 GBCGDNIH2_RS02395 08190c149fd3614b8a6c712c92973c69 941 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 409 424 6.2E-30 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 GBCGDNIH2_RS02395 08190c149fd3614b8a6c712c92973c69 941 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 56 67 6.2E-30 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 GBCGDNIH2_RS02395 08190c149fd3614b8a6c712c92973c69 941 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 569 578 6.2E-30 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 GBCGDNIH2_RS02395 08190c149fd3614b8a6c712c92973c69 941 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 238 261 6.2E-30 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 GBCGDNIH2_RS02395 08190c149fd3614b8a6c712c92973c69 941 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 63 74 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 GBCGDNIH2_RS02395 08190c149fd3614b8a6c712c92973c69 941 Pfam PF08264 Anticodon-binding domain of tRNA 692 844 5.2E-19 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 GBCGDNIH2_RS02395 08190c149fd3614b8a6c712c92973c69 941 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 33 648 1.4E-193 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 GBCGDNIH2_RS02395 08190c149fd3614b8a6c712c92973c69 941 Gene3D G3DSA:3.40.50.620 52 216 6.4E-36 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GBCGDNIH2_RS02395 08190c149fd3614b8a6c712c92973c69 941 Gene3D G3DSA:3.40.50.620 409 607 3.6E-50 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GBCGDNIH2_RS02395 08190c149fd3614b8a6c712c92973c69 941 SUPERFAMILY SSF52374 411 655 5.2E-130 T 29-03-2018 GBCGDNIH2_RS02395 08190c149fd3614b8a6c712c92973c69 941 SUPERFAMILY SSF52374 18 212 5.2E-130 T 29-03-2018 GBCGDNIH2_RS02395 08190c149fd3614b8a6c712c92973c69 941 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 20 845 3.5E-255 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 GBCGDNIH2_RS02395 08190c149fd3614b8a6c712c92973c69 941 Gene3D G3DSA:1.10.730.10 608 836 2.3E-55 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 GBCGDNIH2_RS02395 08190c149fd3614b8a6c712c92973c69 941 Gene3D G3DSA:3.90.740.10 217 408 1.2E-64 T 29-03-2018 GBCGDNIH2_RS02395 08190c149fd3614b8a6c712c92973c69 941 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 7 933 19.937 T 29-03-2018 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 GBCGDNIH2_RS11180 edcf24642feafeac46e28ba95dee5e49 240 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 230 1.9E-15 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 GBCGDNIH2_RS11180 edcf24642feafeac46e28ba95dee5e49 240 Gene3D G3DSA:3.40.50.2300 18 129 3.0E-5 T 29-03-2018 GBCGDNIH2_RS11180 edcf24642feafeac46e28ba95dee5e49 240 SUPERFAMILY SSF52172 68 127 8.9E-5 T 29-03-2018 IPR011006 CheY-like superfamily GBCGDNIH2_RS11180 edcf24642feafeac46e28ba95dee5e49 240 Gene3D G3DSA:1.10.10.10 130 237 5.2E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS11180 edcf24642feafeac46e28ba95dee5e49 240 SMART SM00862 155 230 8.1E-12 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 GBCGDNIH2_RS11180 edcf24642feafeac46e28ba95dee5e49 240 SUPERFAMILY SSF46894 136 232 1.56E-20 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 GBCGDNIH2_RS02210 6646480734200b696225ebc8dfbcb813 384 Gene3D G3DSA:3.40.50.2000 182 362 1.7E-27 T 29-03-2018 GBCGDNIH2_RS02210 6646480734200b696225ebc8dfbcb813 384 SUPERFAMILY SSF53756 9 368 2.33E-93 T 29-03-2018 GBCGDNIH2_RS02210 6646480734200b696225ebc8dfbcb813 384 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 10 145 4.8E-21 T 29-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 GBCGDNIH2_RS02210 6646480734200b696225ebc8dfbcb813 384 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 10 368 31.442 T 29-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 GBCGDNIH2_RS02210 6646480734200b696225ebc8dfbcb813 384 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 194 359 4.7E-35 T 29-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 GBCGDNIH2_RS02210 6646480734200b696225ebc8dfbcb813 384 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 7 363 1.2E-75 T 29-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 GBCGDNIH2_RS02210 6646480734200b696225ebc8dfbcb813 384 Gene3D G3DSA:3.40.50.2000 2 181 1.0E-22 T 29-03-2018 GBCGDNIH2_RS10800 9224953e08570f90d4d1dd32f92749fa 209 SMART SM00702 18 183 0.0049 T 29-03-2018 IPR006620 Prolyl 4-hydroxylase, alpha subunit GO:0005506|GO:0016705|GO:0031418|GO:0055114 GBCGDNIH2_RS10800 9224953e08570f90d4d1dd32f92749fa 209 Gene3D G3DSA:2.60.120.620 16 190 8.3E-13 T 29-03-2018 GBCGDNIH2_RS10800 9224953e08570f90d4d1dd32f92749fa 209 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 102 182 5.7E-8 T 29-03-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 GBCGDNIH2_RS10515 251a00130cc255ab8db90e2aeebb6838 573 PRINTS PR00072 Malic enzyme signature 274 290 3.1E-67 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 GBCGDNIH2_RS10515 251a00130cc255ab8db90e2aeebb6838 573 PRINTS PR00072 Malic enzyme signature 94 118 3.1E-67 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 GBCGDNIH2_RS10515 251a00130cc255ab8db90e2aeebb6838 573 PRINTS PR00072 Malic enzyme signature 249 267 3.1E-67 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 GBCGDNIH2_RS10515 251a00130cc255ab8db90e2aeebb6838 573 PRINTS PR00072 Malic enzyme signature 154 183 3.1E-67 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 GBCGDNIH2_RS10515 251a00130cc255ab8db90e2aeebb6838 573 PRINTS PR00072 Malic enzyme signature 305 321 3.1E-67 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 GBCGDNIH2_RS10515 251a00130cc255ab8db90e2aeebb6838 573 PRINTS PR00072 Malic enzyme signature 414 430 3.1E-67 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 GBCGDNIH2_RS10515 251a00130cc255ab8db90e2aeebb6838 573 PRINTS PR00072 Malic enzyme signature 190 212 3.1E-67 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 GBCGDNIH2_RS10515 251a00130cc255ab8db90e2aeebb6838 573 Pfam PF03949 Malic enzyme, NAD binding domain 278 534 1.7E-95 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 GBCGDNIH2_RS10515 251a00130cc255ab8db90e2aeebb6838 573 SUPERFAMILY SSF51735 278 569 7.88E-91 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS10515 251a00130cc255ab8db90e2aeebb6838 573 SMART SM00919 278 537 1.0E-120 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 GBCGDNIH2_RS10515 251a00130cc255ab8db90e2aeebb6838 573 Gene3D G3DSA:3.40.50.720 276 573 4.3E-104 T 29-03-2018 GBCGDNIH2_RS10515 251a00130cc255ab8db90e2aeebb6838 573 Gene3D G3DSA:3.40.50.10380 22 275 2.6E-108 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 GBCGDNIH2_RS10515 251a00130cc255ab8db90e2aeebb6838 573 SMART SM01274 88 268 1.5E-101 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 GBCGDNIH2_RS10515 251a00130cc255ab8db90e2aeebb6838 573 ProSitePatterns PS00331 Malic enzymes signature. 274 290 - T 29-03-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 GBCGDNIH2_RS10515 251a00130cc255ab8db90e2aeebb6838 573 Pfam PF00390 Malic enzyme, N-terminal domain 88 268 4.7E-70 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 GBCGDNIH2_RS10515 251a00130cc255ab8db90e2aeebb6838 573 PIRSF PIRSF000106 3 569 2.6E-222 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 GBCGDNIH2_RS10515 251a00130cc255ab8db90e2aeebb6838 573 SUPERFAMILY SSF53223 12 277 3.96E-103 T 29-03-2018 GBCGDNIH2_RS00530 e12c8242f379a425aae9b94e3c551eda 299 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 5 290 8.8E-92 T 29-03-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 GBCGDNIH2_RS00530 e12c8242f379a425aae9b94e3c551eda 299 Gene3D G3DSA:3.90.25.10 199 279 6.3E-21 T 29-03-2018 GBCGDNIH2_RS00530 e12c8242f379a425aae9b94e3c551eda 299 Pfam PF04321 RmlD substrate binding domain 5 292 2.3E-104 T 29-03-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 GBCGDNIH2_RS00530 e12c8242f379a425aae9b94e3c551eda 299 Gene3D G3DSA:3.40.50.720 2 198 4.0E-29 T 29-03-2018 GBCGDNIH2_RS00530 e12c8242f379a425aae9b94e3c551eda 299 SUPERFAMILY SSF51735 5 292 6.03E-94 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS09895 f43692b132b436043aad60deccb55b1f 459 Pfam PF13520 Amino acid permease 19 428 1.0E-37 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 GBCGDNIH2_RS09895 f43692b132b436043aad60deccb55b1f 459 PIRSF PIRSF006060 2 456 3.8E-70 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 GBCGDNIH2_RS09895 f43692b132b436043aad60deccb55b1f 459 TIGRFAM TIGR00908 2A0305: ethanolamine permease 13 452 1.8E-173 T 29-03-2018 IPR004757 Ethanolamine permease GBCGDNIH2_RS09585 7a6c5275715c9480caffc5673f212054 410 SUPERFAMILY SSF141130 213 383 3.01E-77 T 29-03-2018 GBCGDNIH2_RS09585 7a6c5275715c9480caffc5673f212054 410 SUPERFAMILY SSF141130 14 164 3.01E-77 T 29-03-2018 GBCGDNIH2_RS09585 7a6c5275715c9480caffc5673f212054 410 Gene3D G3DSA:3.10.28.20 288 383 8.3E-15 T 29-03-2018 GBCGDNIH2_RS09585 7a6c5275715c9480caffc5673f212054 410 Gene3D G3DSA:2.60.120.580 150 281 1.9E-32 T 29-03-2018 GBCGDNIH2_RS09585 7a6c5275715c9480caffc5673f212054 410 Gene3D G3DSA:2.60.120.580 1 149 5.4E-34 T 29-03-2018 GBCGDNIH2_RS09585 7a6c5275715c9480caffc5673f212054 410 Pfam PF03069 Acetamidase/Formamidase family 7 384 1.2E-173 T 29-03-2018 IPR004304 Acetamidase/Formamidase GO:0016811 GBCGDNIH2_RS06590 231798f4608413b2b353bbecbfe878fa 776 SUPERFAMILY SSF55785 389 487 2.99E-6 T 29-03-2018 IPR000014 PAS domain GBCGDNIH2_RS06590 231798f4608413b2b353bbecbfe878fa 776 SMART SM00304 335 388 1.2E-12 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 GBCGDNIH2_RS06590 231798f4608413b2b353bbecbfe878fa 776 SMART SM00388 528 599 6.3E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GBCGDNIH2_RS06590 231798f4608413b2b353bbecbfe878fa 776 Gene3D G3DSA:1.10.287.130 525 595 1.4E-10 T 29-03-2018 GBCGDNIH2_RS06590 231798f4608413b2b353bbecbfe878fa 776 PIRSF PIRSF037532 15 769 1.4E-237 T 29-03-2018 IPR017232 Signal transduction histidine kinase, nitrogen fixation and metabolism regulator GBCGDNIH2_RS06590 231798f4608413b2b353bbecbfe878fa 776 Gene3D G3DSA:3.30.450.20 386 524 6.5E-11 T 29-03-2018 GBCGDNIH2_RS06590 231798f4608413b2b353bbecbfe878fa 776 Pfam PF00512 His Kinase A (phospho-acceptor) domain 531 596 2.0E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GBCGDNIH2_RS06590 231798f4608413b2b353bbecbfe878fa 776 Gene3D G3DSA:3.30.565.10 601 772 2.7E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS06590 231798f4608413b2b353bbecbfe878fa 776 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 640 764 1.5E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS06590 231798f4608413b2b353bbecbfe878fa 776 SMART SM00387 639 765 1.7E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS06590 231798f4608413b2b353bbecbfe878fa 776 PRINTS PR00344 Bacterial sensor protein C-terminal signature 695 709 3.1E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS06590 231798f4608413b2b353bbecbfe878fa 776 PRINTS PR00344 Bacterial sensor protein C-terminal signature 724 742 3.1E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS06590 231798f4608413b2b353bbecbfe878fa 776 PRINTS PR00344 Bacterial sensor protein C-terminal signature 749 762 3.1E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS06590 231798f4608413b2b353bbecbfe878fa 776 SUPERFAMILY SSF55874 598 763 7.07E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS06590 231798f4608413b2b353bbecbfe878fa 776 Pfam PF00672 HAMP domain 336 383 9.4E-11 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 GBCGDNIH2_RS06590 231798f4608413b2b353bbecbfe878fa 776 SUPERFAMILY SSF158472 337 385 5.75E-10 T 29-03-2018 GBCGDNIH2_RS06590 231798f4608413b2b353bbecbfe878fa 776 SUPERFAMILY SSF47384 523 597 8.83E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GBCGDNIH2_RS11225 e7e744d8519fce83284aa42132a17161 240 Hamap MF_01384 Urease accessory protein UreD [ureD]. 9 224 19.033 T 29-03-2018 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 GBCGDNIH2_RS11225 e7e744d8519fce83284aa42132a17161 240 Pfam PF01774 UreD urease accessory protein 16 208 2.2E-41 T 29-03-2018 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 GBCGDNIH2_RS01590 e90466c141db3fb1d1a70927254ee55f 417 Pfam PF00155 Aminotransferase class I and II 47 392 2.9E-73 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 GBCGDNIH2_RS01590 e90466c141db3fb1d1a70927254ee55f 417 TIGRFAM TIGR01821 5aminolev_synth: 5-aminolevulinic acid synthase 4 395 1.1E-172 T 29-03-2018 IPR010961 Tetrapyrrole biosynthesis, 5-aminolevulinic acid synthase GO:0003870|GO:0030170|GO:0033014 KEGG: 00260+2.3.1.37|KEGG: 00860+2.3.1.37|MetaCyc: PWY-5189|MetaCyc: PWY-7536|Reactome: R-HSA-189451 GBCGDNIH2_RS01590 e90466c141db3fb1d1a70927254ee55f 417 SUPERFAMILY SSF53383 9 393 1.88E-105 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase GBCGDNIH2_RS01590 e90466c141db3fb1d1a70927254ee55f 417 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 246 255 - T 29-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 GBCGDNIH2_RS01590 e90466c141db3fb1d1a70927254ee55f 417 Gene3D G3DSA:3.40.640.10 16 292 2.0E-59 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GBCGDNIH2_RS01590 e90466c141db3fb1d1a70927254ee55f 417 Gene3D G3DSA:3.90.1150.10 293 403 1.0E-25 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 GBCGDNIH2_RS09145 29464f100f1220eb306741020fc18d02 592 Pfam PF01425 Amidase 23 432 5.6E-91 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 GBCGDNIH2_RS09145 29464f100f1220eb306741020fc18d02 592 TIGRFAM TIGR02713 allophanate_hyd: allophanate hydrolase 38 591 3.8E-246 T 29-03-2018 IPR014085 Allophanate hydrolase KEGG: 00220+3.5.1.54|KEGG: 00791+3.5.1.54|MetaCyc: PWY-5169|MetaCyc: PWY-5703 GBCGDNIH2_RS09145 29464f100f1220eb306741020fc18d02 592 SUPERFAMILY SSF75304 11 441 1.96E-112 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 GBCGDNIH2_RS09145 29464f100f1220eb306741020fc18d02 592 Gene3D G3DSA:3.10.490.10 461 592 9.3E-29 T 29-03-2018 GBCGDNIH2_RS09145 29464f100f1220eb306741020fc18d02 592 Gene3D G3DSA:3.90.1300.10 1 451 1.5E-117 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 GBCGDNIH2_RS06075 1fd883d3e558069a2731bba14c8ef1e7 93 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 2 67 29.532 T 29-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 GBCGDNIH2_RS06075 1fd883d3e558069a2731bba14c8ef1e7 93 Gene3D G3DSA:2.30.30.100 6 76 2.4E-33 T 29-03-2018 GBCGDNIH2_RS06075 1fd883d3e558069a2731bba14c8ef1e7 93 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 7 67 6.4E-33 T 29-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 GBCGDNIH2_RS06075 1fd883d3e558069a2731bba14c8ef1e7 93 Pfam PF17209 Hfq protein 9 71 8.8E-33 T 29-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 GBCGDNIH2_RS06075 1fd883d3e558069a2731bba14c8ef1e7 93 SUPERFAMILY SSF50182 8 67 1.51E-24 T 29-03-2018 IPR010920 LSM domain GBCGDNIH2_RS00750 c7b317b658b934165809ce9a01a8d1af 811 Pfam PF08482 ATP-dependent helicase C-terminal 692 808 5.2E-41 T 29-03-2018 IPR013689 ATP-dependent RNA helicase HrpB, C-terminal GBCGDNIH2_RS00750 c7b317b658b934165809ce9a01a8d1af 811 TIGRFAM TIGR01970 DEAH_box_HrpB: ATP-dependent helicase HrpB 6 809 4.2E-251 T 29-03-2018 IPR010225 ATP-dependent helicase HrpB GO:0008026 GBCGDNIH2_RS00750 c7b317b658b934165809ce9a01a8d1af 811 Gene3D G3DSA:3.40.50.300 8 163 2.9E-22 T 29-03-2018 GBCGDNIH2_RS00750 c7b317b658b934165809ce9a01a8d1af 811 SMART SM00490 228 327 1.5E-18 T 29-03-2018 IPR001650 Helicase, C-terminal GBCGDNIH2_RS00750 c7b317b658b934165809ce9a01a8d1af 811 SMART SM00847 386 479 8.7E-14 T 29-03-2018 IPR007502 Helicase-associated domain GO:0004386 GBCGDNIH2_RS00750 c7b317b658b934165809ce9a01a8d1af 811 Pfam PF00271 Helicase conserved C-terminal domain 210 325 3.2E-12 T 29-03-2018 IPR001650 Helicase, C-terminal GBCGDNIH2_RS00750 c7b317b658b934165809ce9a01a8d1af 811 Pfam PF04408 Helicase associated domain (HA2) 387 459 1.7E-15 T 29-03-2018 IPR007502 Helicase-associated domain GO:0004386 GBCGDNIH2_RS00750 c7b317b658b934165809ce9a01a8d1af 811 SMART SM00487 3 186 9.5E-14 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain GBCGDNIH2_RS00750 c7b317b658b934165809ce9a01a8d1af 811 SUPERFAMILY SSF52540 21 338 4.59E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS00750 c7b317b658b934165809ce9a01a8d1af 811 Gene3D G3DSA:3.40.50.300 180 347 7.1E-39 T 29-03-2018 GBCGDNIH2_RS00750 c7b317b658b934165809ce9a01a8d1af 811 PIRSF PIRSF005496 1 811 1.4E-259 T 29-03-2018 GBCGDNIH2_RS11565 60af3188485727becfe65c7c3b41bab9 193 Pfam PF00583 Acetyltransferase (GNAT) family 55 158 4.0E-10 T 29-03-2018 IPR000182 GNAT domain GO:0008080 GBCGDNIH2_RS11565 60af3188485727becfe65c7c3b41bab9 193 Gene3D G3DSA:3.40.630.30 21 191 7.0E-23 T 29-03-2018 GBCGDNIH2_RS11565 60af3188485727becfe65c7c3b41bab9 193 SUPERFAMILY SSF55729 24 184 6.0E-24 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase GBCGDNIH2_RS10705 f3b431a06915daeab422e473bea9866c 287 Gene3D G3DSA:1.10.620.20 1 266 7.3E-42 T 29-03-2018 GBCGDNIH2_RS10705 f3b431a06915daeab422e473bea9866c 287 SUPERFAMILY SSF47240 1 269 2.92E-50 T 29-03-2018 IPR009078 Ferritin-like superfamily GBCGDNIH2_RS03725 dadf3b36e4b53e930d67e295f85bbc65 335 SUPERFAMILY SSF56024 160 319 5.16E-28 T 29-03-2018 GBCGDNIH2_RS03725 dadf3b36e4b53e930d67e295f85bbc65 335 Pfam PF13091 PLD-like domain 25 151 3.1E-22 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 GBCGDNIH2_RS03725 dadf3b36e4b53e930d67e295f85bbc65 335 Pfam PF13091 PLD-like domain 176 303 2.6E-26 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 GBCGDNIH2_RS03725 dadf3b36e4b53e930d67e295f85bbc65 335 Gene3D G3DSA:3.30.870.10 166 331 8.4E-28 T 29-03-2018 GBCGDNIH2_RS03725 dadf3b36e4b53e930d67e295f85bbc65 335 Gene3D G3DSA:3.30.870.10 22 160 2.0E-28 T 29-03-2018 GBCGDNIH2_RS03725 dadf3b36e4b53e930d67e295f85bbc65 335 SUPERFAMILY SSF56024 12 153 1.05E-26 T 29-03-2018 GBCGDNIH2_RS03725 dadf3b36e4b53e930d67e295f85bbc65 335 SMART SM00155 96 123 7.6 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 GBCGDNIH2_RS03725 dadf3b36e4b53e930d67e295f85bbc65 335 SMART SM00155 248 275 0.002 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 GBCGDNIH2_RS03390 232ba9898f24de0b186ef439bf9e957a 253 SUPERFAMILY SSF53790 2 248 1.13E-58 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GBCGDNIH2_RS03390 232ba9898f24de0b186ef439bf9e957a 253 Gene3D G3DSA:3.30.950.10 121 234 1.5E-25 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GBCGDNIH2_RS03390 232ba9898f24de0b186ef439bf9e957a 253 TIGRFAM TIGR01465 cobM_cbiF: precorrin-4 C11-methyltransferase 3 249 3.8E-89 T 29-03-2018 IPR006362 Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase GO:0009236|GO:0046026 GBCGDNIH2_RS03390 232ba9898f24de0b186ef439bf9e957a 253 Gene3D G3DSA:3.40.1010.10 1 120 1.8E-23 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GBCGDNIH2_RS03390 232ba9898f24de0b186ef439bf9e957a 253 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 6 20 - T 29-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 GBCGDNIH2_RS03390 232ba9898f24de0b186ef439bf9e957a 253 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 208 1.2E-35 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GBCGDNIH2_RS08525 15d420f6342f2d09af1314f0c7881a95 642 Gene3D G3DSA:3.10.20.30 1 63 3.2E-16 T 29-03-2018 IPR012675 Beta-grasp domain GBCGDNIH2_RS08525 15d420f6342f2d09af1314f0c7881a95 642 SUPERFAMILY SSF52954 531 634 2.11E-26 T 29-03-2018 IPR004154 Anticodon-binding GBCGDNIH2_RS08525 15d420f6342f2d09af1314f0c7881a95 642 SMART SM00863 169 219 9.5E-24 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 GBCGDNIH2_RS08525 15d420f6342f2d09af1314f0c7881a95 642 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 322 531 3.1E-42 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 GBCGDNIH2_RS08525 15d420f6342f2d09af1314f0c7881a95 642 Gene3D G3DSA:3.30.930.10 229 533 5.7E-120 T 29-03-2018 GBCGDNIH2_RS08525 15d420f6342f2d09af1314f0c7881a95 642 PRINTS PR01047 Threonyl-tRNA synthetase signature 466 494 2.6E-53 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 GBCGDNIH2_RS08525 15d420f6342f2d09af1314f0c7881a95 642 PRINTS PR01047 Threonyl-tRNA synthetase signature 536 548 2.6E-53 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 GBCGDNIH2_RS08525 15d420f6342f2d09af1314f0c7881a95 642 PRINTS PR01047 Threonyl-tRNA synthetase signature 364 387 2.6E-53 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 GBCGDNIH2_RS08525 15d420f6342f2d09af1314f0c7881a95 642 PRINTS PR01047 Threonyl-tRNA synthetase signature 509 522 2.6E-53 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 GBCGDNIH2_RS08525 15d420f6342f2d09af1314f0c7881a95 642 PRINTS PR01047 Threonyl-tRNA synthetase signature 331 359 2.6E-53 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 GBCGDNIH2_RS08525 15d420f6342f2d09af1314f0c7881a95 642 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 66 637 32.836 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 GBCGDNIH2_RS08525 15d420f6342f2d09af1314f0c7881a95 642 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 72 633 6.3E-206 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 GBCGDNIH2_RS08525 15d420f6342f2d09af1314f0c7881a95 642 SUPERFAMILY SSF55681 243 528 2.49E-98 T 29-03-2018 GBCGDNIH2_RS08525 15d420f6342f2d09af1314f0c7881a95 642 SUPERFAMILY SSF81271 3 61 2.22E-13 T 29-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 GBCGDNIH2_RS08525 15d420f6342f2d09af1314f0c7881a95 642 SUPERFAMILY SSF55186 64 241 1.1E-64 T 29-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 GBCGDNIH2_RS08525 15d420f6342f2d09af1314f0c7881a95 642 Gene3D G3DSA:3.30.980.10 64 228 2.3E-45 T 29-03-2018 GBCGDNIH2_RS08525 15d420f6342f2d09af1314f0c7881a95 642 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 169 219 9.0E-13 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 GBCGDNIH2_RS08525 15d420f6342f2d09af1314f0c7881a95 642 Gene3D G3DSA:3.40.50.800 534 636 1.2E-24 T 29-03-2018 IPR004154 Anticodon-binding GBCGDNIH2_RS08525 15d420f6342f2d09af1314f0c7881a95 642 Pfam PF03129 Anticodon binding domain 544 632 9.8E-18 T 29-03-2018 IPR004154 Anticodon-binding GBCGDNIH2_RS05390 65bc940d1055cbcc9d9693aa3d7320dd 737 SUPERFAMILY SSF56719 32 480 6.93E-152 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 GBCGDNIH2_RS05390 65bc940d1055cbcc9d9693aa3d7320dd 737 TIGRFAM TIGR01062 parC_Gneg: DNA topoisomerase IV, A subunit 10 735 8.5E-259 T 29-03-2018 GBCGDNIH2_RS05390 65bc940d1055cbcc9d9693aa3d7320dd 737 Gene3D G3DSA:1.10.268.10 347 490 2.0E-40 T 29-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GBCGDNIH2_RS05390 65bc940d1055cbcc9d9693aa3d7320dd 737 Gene3D G3DSA:2.120.10.90 501 685 1.5E-34 T 29-03-2018 GBCGDNIH2_RS05390 65bc940d1055cbcc9d9693aa3d7320dd 737 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 33 459 2.0E-137 T 29-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GBCGDNIH2_RS05390 65bc940d1055cbcc9d9693aa3d7320dd 737 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 552 597 1.1 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 GBCGDNIH2_RS05390 65bc940d1055cbcc9d9693aa3d7320dd 737 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 605 642 0.38 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 GBCGDNIH2_RS05390 65bc940d1055cbcc9d9693aa3d7320dd 737 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 649 679 0.0068 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 GBCGDNIH2_RS05390 65bc940d1055cbcc9d9693aa3d7320dd 737 SUPERFAMILY SSF101904 508 732 2.88E-44 T 29-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal GBCGDNIH2_RS05390 65bc940d1055cbcc9d9693aa3d7320dd 737 Hamap MF_00936 DNA topoisomerase 4 subunit A [parC]. 5 736 31.864 T 29-03-2018 IPR005742 DNA topoisomerase IV, subunit A, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 GBCGDNIH2_RS05390 65bc940d1055cbcc9d9693aa3d7320dd 737 Gene3D G3DSA:3.90.199.10 35 288 4.6E-109 T 29-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 GBCGDNIH2_RS05390 65bc940d1055cbcc9d9693aa3d7320dd 737 SMART SM00434 12 464 5.8E-222 T 29-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GBCGDNIH2_RS00300 8fef3b727bf664871dae9431c3733c90 645 SUPERFAMILY SSF53448 315 454 1.26E-5 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS00300 8fef3b727bf664871dae9431c3733c90 645 Pfam PF13704 Glycosyl transferase family 2 322 414 2.5E-15 T 29-03-2018 GBCGDNIH2_RS00300 8fef3b727bf664871dae9431c3733c90 645 Gene3D G3DSA:3.90.550.10 314 546 9.8E-4 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS05810 da90032c6676ed62b398ef56c60f7c21 207 SUPERFAMILY SSF48498 81 198 8.23E-20 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal GBCGDNIH2_RS05810 da90032c6676ed62b398ef56c60f7c21 207 Gene3D G3DSA:1.10.357.10 57 199 7.4E-18 T 29-03-2018 GBCGDNIH2_RS05810 da90032c6676ed62b398ef56c60f7c21 207 SUPERFAMILY SSF46689 2 75 3.39E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 GBCGDNIH2_RS05810 da90032c6676ed62b398ef56c60f7c21 207 Pfam PF13305 WHG domain 88 169 2.2E-12 T 29-03-2018 IPR025996 WHG domain GBCGDNIH2_RS05810 da90032c6676ed62b398ef56c60f7c21 207 Gene3D G3DSA:1.10.10.60 8 56 7.3E-14 T 29-03-2018 GBCGDNIH2_RS05810 da90032c6676ed62b398ef56c60f7c21 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 59 1.4E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GBCGDNIH2_RS05810 da90032c6676ed62b398ef56c60f7c21 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 1.3E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GBCGDNIH2_RS05810 da90032c6676ed62b398ef56c60f7c21 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 1.3E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GBCGDNIH2_RS10535 e8455d82a0c67433f5289609fee9e5ce 107 PRINTS PR01727 Prokaryotic integration host factor signature 75 89 8.9E-17 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 GBCGDNIH2_RS10535 e8455d82a0c67433f5289609fee9e5ce 107 PRINTS PR01727 Prokaryotic integration host factor signature 41 56 8.9E-17 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 GBCGDNIH2_RS10535 e8455d82a0c67433f5289609fee9e5ce 107 PRINTS PR01727 Prokaryotic integration host factor signature 59 72 8.9E-17 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 GBCGDNIH2_RS10535 e8455d82a0c67433f5289609fee9e5ce 107 Gene3D G3DSA:4.10.520.10 1 98 5.7E-31 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 GBCGDNIH2_RS10535 e8455d82a0c67433f5289609fee9e5ce 107 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 47 66 - T 29-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 GBCGDNIH2_RS10535 e8455d82a0c67433f5289609fee9e5ce 107 Pfam PF00216 Bacterial DNA-binding protein 1 91 1.8E-30 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 GBCGDNIH2_RS10535 e8455d82a0c67433f5289609fee9e5ce 107 SUPERFAMILY SSF47729 1 93 1.62E-30 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 GBCGDNIH2_RS10535 e8455d82a0c67433f5289609fee9e5ce 107 SMART SM00411 1 91 1.8E-40 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 GBCGDNIH2_RS10535 e8455d82a0c67433f5289609fee9e5ce 107 Hamap MF_00381 Integration host factor subunit beta [ihfB]. 1 94 28.429 T 29-03-2018 IPR005685 Integration host factor, beta subunit GO:0003677|GO:0005694|GO:0006310|GO:0006355 GBCGDNIH2_RS10535 e8455d82a0c67433f5289609fee9e5ce 107 TIGRFAM TIGR00988 hip: integration host factor, beta subunit 1 93 1.1E-42 T 29-03-2018 IPR005685 Integration host factor, beta subunit GO:0003677|GO:0005694|GO:0006310|GO:0006355 GBCGDNIH2_RS06900 3289c2bc116e05904a20b14b18c88f5a 269 SUPERFAMILY SSF53067 1 122 2.43E-33 T 29-03-2018 GBCGDNIH2_RS06900 3289c2bc116e05904a20b14b18c88f5a 269 Pfam PF03309 Type III pantothenate kinase 2 205 1.0E-70 T 29-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 GBCGDNIH2_RS06900 3289c2bc116e05904a20b14b18c88f5a 269 SUPERFAMILY SSF53067 123 250 8.2E-40 T 29-03-2018 GBCGDNIH2_RS06900 3289c2bc116e05904a20b14b18c88f5a 269 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 2 249 4.6E-67 T 29-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 GBCGDNIH2_RS06900 3289c2bc116e05904a20b14b18c88f5a 269 Gene3D G3DSA:3.30.420.40 90 266 1.3E-60 T 29-03-2018 GBCGDNIH2_RS06900 3289c2bc116e05904a20b14b18c88f5a 269 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 254 36.091 T 29-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 GBCGDNIH2_RS05715 c5f3cfbbbbf2e657ef551bd1f9b0cba7 298 Gene3D G3DSA:1.10.10.10 2 87 3.4E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS05715 c5f3cfbbbbf2e657ef551bd1f9b0cba7 298 SUPERFAMILY SSF53850 91 298 2.9E-24 T 29-03-2018 GBCGDNIH2_RS05715 c5f3cfbbbbf2e657ef551bd1f9b0cba7 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 66 9.7E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS05715 c5f3cfbbbbf2e657ef551bd1f9b0cba7 298 Pfam PF03466 LysR substrate binding domain 91 297 7.1E-21 T 29-03-2018 IPR005119 LysR, substrate-binding GBCGDNIH2_RS05715 c5f3cfbbbbf2e657ef551bd1f9b0cba7 298 SUPERFAMILY SSF46785 6 91 6.66E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS05715 c5f3cfbbbbf2e657ef551bd1f9b0cba7 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 2.7E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS05715 c5f3cfbbbbf2e657ef551bd1f9b0cba7 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 2.7E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS05715 c5f3cfbbbbf2e657ef551bd1f9b0cba7 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 2.7E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS05715 c5f3cfbbbbf2e657ef551bd1f9b0cba7 298 Gene3D G3DSA:3.40.190.10 183 260 1.6E-11 T 29-03-2018 GBCGDNIH2_RS05715 c5f3cfbbbbf2e657ef551bd1f9b0cba7 298 Gene3D G3DSA:3.40.190.10 92 182 1.5E-11 T 29-03-2018 GBCGDNIH2_RS10140 ff1c918f1a3b12646af6d3e56c77c3ad 109 Gene3D G3DSA:3.10.20.30 2 108 1.4E-37 T 29-03-2018 IPR012675 Beta-grasp domain GBCGDNIH2_RS10140 ff1c918f1a3b12646af6d3e56c77c3ad 109 SUPERFAMILY SSF54292 1 101 9.3E-34 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 GBCGDNIH2_RS10140 ff1c918f1a3b12646af6d3e56c77c3ad 109 ProSitePatterns PS00814 Adrenodoxin family, iron-sulfur binding region signature. 39 49 - T 29-03-2018 IPR018298 Adrenodoxin, iron-sulphur binding site GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 GBCGDNIH2_RS10140 ff1c918f1a3b12646af6d3e56c77c3ad 109 PRINTS PR00355 Adrenodoxin signature 81 89 1.8E-11 T 29-03-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 GBCGDNIH2_RS10140 ff1c918f1a3b12646af6d3e56c77c3ad 109 PRINTS PR00355 Adrenodoxin signature 39 49 1.8E-11 T 29-03-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 GBCGDNIH2_RS10140 ff1c918f1a3b12646af6d3e56c77c3ad 109 PRINTS PR00355 Adrenodoxin signature 58 72 1.8E-11 T 29-03-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 GBCGDNIH2_RS10140 ff1c918f1a3b12646af6d3e56c77c3ad 109 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 8 90 8.6E-15 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 GBCGDNIH2_RS06020 2eef790e0f6e8471bc51ef1130ffc9ea 329 TIGRFAM TIGR01840 esterase_phb: esterase, PHB depolymerase family 52 259 1.7E-40 T 29-03-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 GBCGDNIH2_RS06020 2eef790e0f6e8471bc51ef1130ffc9ea 329 Gene3D G3DSA:3.40.50.1820 11 307 9.4E-30 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS06020 2eef790e0f6e8471bc51ef1130ffc9ea 329 SUPERFAMILY SSF53474 23 187 7.65E-19 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS06020 2eef790e0f6e8471bc51ef1130ffc9ea 329 SUPERFAMILY SSF53474 285 324 5.27E-33 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS06020 2eef790e0f6e8471bc51ef1130ffc9ea 329 SUPERFAMILY SSF53474 138 258 5.27E-33 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS06020 2eef790e0f6e8471bc51ef1130ffc9ea 329 Pfam PF10503 Esterase PHB depolymerase 56 254 1.9E-32 T 29-03-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 GBCGDNIH2_RS10335 da89456baf6cd2163acd19672c335886 344 SUPERFAMILY SSF51735 3 263 3.78E-71 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS10335 da89456baf6cd2163acd19672c335886 344 SUPERFAMILY SSF51735 296 327 3.78E-71 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS10335 da89456baf6cd2163acd19672c335886 344 Gene3D G3DSA:3.40.50.720 2 332 9.7E-72 T 29-03-2018 GBCGDNIH2_RS10335 da89456baf6cd2163acd19672c335886 344 TIGRFAM TIGR03466 HpnA: hopanoid-associated sugar epimerase 6 330 5.5E-145 T 29-03-2018 IPR017829 Hopanoid-associated sugar epimerase KEGG: 00040+1.1.1.21|KEGG: 00051+1.1.1.21|KEGG: 00052+1.1.1.21|KEGG: 00561+1.1.1.21|KEGG: 00941+1.1.1.219|MetaCyc: PWY-5152|MetaCyc: PWY-5515|MetaCyc: PWY-5516|MetaCyc: PWY-6693 GBCGDNIH2_RS10335 da89456baf6cd2163acd19672c335886 344 Pfam PF01370 NAD dependent epimerase/dehydratase family 8 234 2.1E-39 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 GBCGDNIH2_RS10025 0c1c5073f49cd1fe44424dff25352ac4 287 Gene3D G3DSA:3.40.190.10 29 144 1.2E-5 T 29-03-2018 GBCGDNIH2_RS10025 0c1c5073f49cd1fe44424dff25352ac4 287 TIGRFAM TIGR03871 ABC_peri_MoxJ_2: quinoprotein dehydrogenase-associated probable ABC transporter substrate-binding protein 41 271 6.4E-94 T 29-03-2018 IPR022448 Quinoprotein dehydrogenase-associated GBCGDNIH2_RS10025 0c1c5073f49cd1fe44424dff25352ac4 287 Gene3D G3DSA:3.40.190.10 145 245 1.5E-8 T 29-03-2018 GBCGDNIH2_RS10025 0c1c5073f49cd1fe44424dff25352ac4 287 SUPERFAMILY SSF53850 37 257 3.45E-24 T 29-03-2018 GBCGDNIH2_RS10025 0c1c5073f49cd1fe44424dff25352ac4 287 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 44 254 6.0E-14 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF GBCGDNIH2_RS10025 0c1c5073f49cd1fe44424dff25352ac4 287 SMART SM00062 41 265 4.2E-20 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF GBCGDNIH2_RS07800 e628ea5edee7a571707c9ea89481754a 378 SUPERFAMILY SSF53448 23 234 1.55E-34 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS07800 e628ea5edee7a571707c9ea89481754a 378 Pfam PF04138 GtrA-like protein 261 375 7.2E-16 T 29-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 GBCGDNIH2_RS07800 e628ea5edee7a571707c9ea89481754a 378 Gene3D G3DSA:3.90.550.10 5 237 8.2E-32 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS07800 e628ea5edee7a571707c9ea89481754a 378 Pfam PF00535 Glycosyl transferase family 2 24 189 1.6E-28 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 GBCGDNIH2_RS10240 bbd2b911a5c02a6ad8c49d52bc8fa690 277 Gene3D G3DSA:3.20.20.70 22 277 1.3E-49 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS10240 bbd2b911a5c02a6ad8c49d52bc8fa690 277 Hamap MF_00443 Thiazole synthase [thiG]. 24 277 41.759 T 29-03-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 GBCGDNIH2_RS10240 bbd2b911a5c02a6ad8c49d52bc8fa690 277 Pfam PF05690 Thiazole biosynthesis protein ThiG 27 271 1.9E-105 T 29-03-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 GBCGDNIH2_RS10240 bbd2b911a5c02a6ad8c49d52bc8fa690 277 SUPERFAMILY SSF110399 23 263 7.98E-86 T 29-03-2018 GBCGDNIH2_RS06875 657d458f76f1899c76c13c590ab76d58 229 Pfam PF00005 ABC transporter 28 176 1.4E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GBCGDNIH2_RS06875 657d458f76f1899c76c13c590ab76d58 229 Gene3D G3DSA:3.40.50.300 5 229 1.2E-52 T 29-03-2018 GBCGDNIH2_RS06875 657d458f76f1899c76c13c590ab76d58 229 SMART SM00382 37 227 9.5E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS06875 657d458f76f1899c76c13c590ab76d58 229 SUPERFAMILY SSF52540 9 227 3.87E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS06875 657d458f76f1899c76c13c590ab76d58 229 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GBCGDNIH2_RS05430 43fce50fe393cbdf45a16f71900a1b9c 163 SUPERFAMILY SSF48013 7 154 1.31E-28 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 GBCGDNIH2_RS05430 43fce50fe393cbdf45a16f71900a1b9c 163 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 1 152 17.563 T 29-03-2018 IPR011605 NusB antitermination factor GO:0006353 GBCGDNIH2_RS05430 43fce50fe393cbdf45a16f71900a1b9c 163 Gene3D G3DSA:1.10.940.10 3 155 2.6E-31 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 GBCGDNIH2_RS05430 43fce50fe393cbdf45a16f71900a1b9c 163 Pfam PF01029 NusB family 10 149 1.0E-22 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 GBCGDNIH2_RS05430 43fce50fe393cbdf45a16f71900a1b9c 163 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 8 150 4.2E-31 T 29-03-2018 IPR011605 NusB antitermination factor GO:0006353 GBCGDNIH2_RS02330 b3c09493250c05418b7b93f73a0153a3 242 SUPERFAMILY SSF56281 5 240 1.82E-63 T 29-03-2018 IPR001279 Metallo-beta-lactamase GBCGDNIH2_RS02330 b3c09493250c05418b7b93f73a0153a3 242 Pfam PF16123 Hydroxyacylglutathione hydrolase C-terminus 173 242 1.0E-20 T 29-03-2018 IPR032282 Hydroxyacylglutathione hydrolase, C-terminal domain KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 GBCGDNIH2_RS02330 b3c09493250c05418b7b93f73a0153a3 242 TIGRFAM TIGR03413 GSH_gloB: hydroxyacylglutathione hydrolase 6 233 2.4E-86 T 29-03-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 GBCGDNIH2_RS02330 b3c09493250c05418b7b93f73a0153a3 242 Gene3D G3DSA:3.60.15.10 1 242 5.5E-60 T 29-03-2018 IPR001279 Metallo-beta-lactamase GBCGDNIH2_RS02330 b3c09493250c05418b7b93f73a0153a3 242 SMART SM00849 13 172 1.4E-32 T 29-03-2018 IPR001279 Metallo-beta-lactamase GBCGDNIH2_RS02330 b3c09493250c05418b7b93f73a0153a3 242 Pfam PF00753 Metallo-beta-lactamase superfamily 29 172 4.9E-18 T 29-03-2018 IPR001279 Metallo-beta-lactamase GBCGDNIH2_RS02330 b3c09493250c05418b7b93f73a0153a3 242 PIRSF PIRSF005457 1 242 8.7E-104 T 29-03-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 GBCGDNIH2_RS02330 b3c09493250c05418b7b93f73a0153a3 242 Hamap MF_01374 Hydroxyacylglutathione hydrolase [gloB]. 3 242 40.793 T 29-03-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 GBCGDNIH2_RS09045 e4bfeea909be55b750e2a6e83de35610 419 Gene3D G3DSA:2.40.50.100 80 148 2.6E-17 T 29-03-2018 GBCGDNIH2_RS09045 e4bfeea909be55b750e2a6e83de35610 419 SUPERFAMILY SSF111369 194 326 5.49E-15 T 29-03-2018 GBCGDNIH2_RS09045 e4bfeea909be55b750e2a6e83de35610 419 Gene3D G3DSA:1.20.1600.10 218 352 2.6E-18 T 29-03-2018 GBCGDNIH2_RS09045 e4bfeea909be55b750e2a6e83de35610 419 Gene3D G3DSA:1.10.287.470 150 210 5.9E-4 T 29-03-2018 GBCGDNIH2_RS09045 e4bfeea909be55b750e2a6e83de35610 419 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 195 327 1.3E-14 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain GBCGDNIH2_RS09045 e4bfeea909be55b750e2a6e83de35610 419 Pfam PF13533 Biotin-lipoyl like 82 129 6.8E-15 T 29-03-2018 GBCGDNIH2_RS09045 e4bfeea909be55b750e2a6e83de35610 419 SUPERFAMILY SSF111369 79 175 1.24E-12 T 29-03-2018 GBCGDNIH2_RS10485 0a85f7e19cc59ec510e9c0f6e2b3ddee 1159 Gene3D G3DSA:3.40.50.300 10 471 5.7E-45 T 29-03-2018 GBCGDNIH2_RS10485 0a85f7e19cc59ec510e9c0f6e2b3ddee 1159 SUPERFAMILY SSF52980 978 1118 1.34E-6 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 GBCGDNIH2_RS10485 0a85f7e19cc59ec510e9c0f6e2b3ddee 1159 Pfam PF13361 UvrD-like helicase C-terminal domain 758 869 9.2E-13 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 GBCGDNIH2_RS10485 0a85f7e19cc59ec510e9c0f6e2b3ddee 1159 TIGRFAM TIGR02784 addA_alphas: double-strand break repair helicase AddA 14 1135 0.0 T 29-03-2018 IPR014151 DNA helicase, AddA type GBCGDNIH2_RS10485 0a85f7e19cc59ec510e9c0f6e2b3ddee 1159 Pfam PF12705 PD-(D/E)XK nuclease superfamily 986 1117 1.1E-6 T 29-03-2018 GBCGDNIH2_RS10485 0a85f7e19cc59ec510e9c0f6e2b3ddee 1159 SUPERFAMILY SSF52540 25 77 2.05E-98 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS10485 0a85f7e19cc59ec510e9c0f6e2b3ddee 1159 SUPERFAMILY SSF52540 115 168 2.05E-98 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS10485 0a85f7e19cc59ec510e9c0f6e2b3ddee 1159 SUPERFAMILY SSF52540 343 539 2.05E-98 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS10485 0a85f7e19cc59ec510e9c0f6e2b3ddee 1159 SUPERFAMILY SSF52540 849 873 2.05E-98 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS10485 0a85f7e19cc59ec510e9c0f6e2b3ddee 1159 SUPERFAMILY SSF52540 566 817 2.05E-98 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS10485 0a85f7e19cc59ec510e9c0f6e2b3ddee 1159 Gene3D G3DSA:3.90.320.10 898 1123 6.5E-13 T 29-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 GBCGDNIH2_RS10485 0a85f7e19cc59ec510e9c0f6e2b3ddee 1159 Pfam PF00580 UvrD/REP helicase N-terminal domain 24 460 3.4E-45 T 29-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 GBCGDNIH2_RS10485 0a85f7e19cc59ec510e9c0f6e2b3ddee 1159 Gene3D G3DSA:3.40.50.300 551 890 4.2E-41 T 29-03-2018 GBCGDNIH2_RS08125 70d4e05c1e21277326bf3f48a39a43b0 410 SUPERFAMILY SSF102114 47 198 2.22E-14 T 29-03-2018 GBCGDNIH2_RS08125 70d4e05c1e21277326bf3f48a39a43b0 410 SUPERFAMILY SSF47781 309 382 5.11E-10 T 29-03-2018 IPR010994 RuvA domain 2-like GBCGDNIH2_RS08125 70d4e05c1e21277326bf3f48a39a43b0 410 Gene3D G3DSA:1.10.150.280 320 390 2.8E-5 T 29-03-2018 GBCGDNIH2_RS08125 70d4e05c1e21277326bf3f48a39a43b0 410 SMART SM00729 58 285 8.7E-4 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 GBCGDNIH2_RS08125 70d4e05c1e21277326bf3f48a39a43b0 410 Gene3D G3DSA:3.20.20.70 1 293 2.1E-35 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS08125 70d4e05c1e21277326bf3f48a39a43b0 410 TIGRFAM TIGR03916 rSAM_link_UDG: putative DNA modification/repair radical SAM protein 6 390 4.1E-169 T 29-03-2018 IPR023874 DNA modification/repair radical SAM protein, putative GBCGDNIH2_RS08125 70d4e05c1e21277326bf3f48a39a43b0 410 Pfam PF04055 Radical SAM superfamily 64 196 1.1E-7 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 GBCGDNIH2_RS11675 b02eb41c65f94e91cf16a23a83dc2282 426 SUPERFAMILY SSF63411 9 220 4.62E-61 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 GBCGDNIH2_RS11675 b02eb41c65f94e91cf16a23a83dc2282 426 Pfam PF00675 Insulinase (Peptidase family M16) 21 167 3.3E-42 T 29-03-2018 IPR011765 Peptidase M16, N-terminal GBCGDNIH2_RS11675 b02eb41c65f94e91cf16a23a83dc2282 426 Pfam PF05193 Peptidase M16 inactive domain 174 344 1.4E-43 T 29-03-2018 IPR007863 Peptidase M16, C-terminal GBCGDNIH2_RS11675 b02eb41c65f94e91cf16a23a83dc2282 426 Gene3D G3DSA:3.30.830.10 2 227 1.1E-63 T 29-03-2018 GBCGDNIH2_RS11675 b02eb41c65f94e91cf16a23a83dc2282 426 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 41 64 - T 29-03-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 GBCGDNIH2_RS11675 b02eb41c65f94e91cf16a23a83dc2282 426 Gene3D G3DSA:3.30.830.10 244 420 8.3E-51 T 29-03-2018 GBCGDNIH2_RS11675 b02eb41c65f94e91cf16a23a83dc2282 426 SUPERFAMILY SSF63411 226 419 1.39E-51 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 GBCGDNIH2_RS10310 f5fefbddfae814b15730b191cd83652e 561 SMART SM00304 275 331 0.0047 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 GBCGDNIH2_RS10310 f5fefbddfae814b15730b191cd83652e 561 SUPERFAMILY SSF47384 315 396 5.49E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GBCGDNIH2_RS10310 f5fefbddfae814b15730b191cd83652e 561 Gene3D G3DSA:1.10.287.130 317 391 9.7E-14 T 29-03-2018 GBCGDNIH2_RS10310 f5fefbddfae814b15730b191cd83652e 561 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 446 559 1.2E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS10310 f5fefbddfae814b15730b191cd83652e 561 SUPERFAMILY SSF55874 387 559 6.81E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS10310 f5fefbddfae814b15730b191cd83652e 561 SMART SM00388 332 397 2.4E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GBCGDNIH2_RS10310 f5fefbddfae814b15730b191cd83652e 561 SMART SM00387 445 561 1.1E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS10310 f5fefbddfae814b15730b191cd83652e 561 Pfam PF13755 Sensor N-terminal transmembrane domain 20 72 2.4E-11 T 29-03-2018 IPR025908 Sensor N-terminal transmembrane domain GBCGDNIH2_RS10310 f5fefbddfae814b15730b191cd83652e 561 Gene3D G3DSA:3.30.450.20 47 248 3.3E-6 T 29-03-2018 GBCGDNIH2_RS10310 f5fefbddfae814b15730b191cd83652e 561 Pfam PF13756 Stimulus-sensing domain 88 214 4.2E-29 T 29-03-2018 IPR025919 Stimulus-sensing domain GBCGDNIH2_RS10310 f5fefbddfae814b15730b191cd83652e 561 Pfam PF00512 His Kinase A (phospho-acceptor) domain 334 396 1.6E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GBCGDNIH2_RS10310 f5fefbddfae814b15730b191cd83652e 561 PRINTS PR00344 Bacterial sensor protein C-terminal signature 482 496 3.9E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS10310 f5fefbddfae814b15730b191cd83652e 561 PRINTS PR00344 Bacterial sensor protein C-terminal signature 517 535 3.9E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS10310 f5fefbddfae814b15730b191cd83652e 561 PRINTS PR00344 Bacterial sensor protein C-terminal signature 500 510 3.9E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS10310 f5fefbddfae814b15730b191cd83652e 561 PRINTS PR00344 Bacterial sensor protein C-terminal signature 546 559 3.9E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS10310 f5fefbddfae814b15730b191cd83652e 561 Gene3D G3DSA:3.30.565.10 392 561 4.2E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS03900 3075b50cb528b1983fa0676045310b6b 590 SMART SM00387 470 570 2.5E-4 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS03900 3075b50cb528b1983fa0676045310b6b 590 Pfam PF13581 Histidine kinase-like ATPase domain 466 548 3.2E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS03900 3075b50cb528b1983fa0676045310b6b 590 Pfam PF07568 Histidine kinase 373 447 5.3E-26 T 29-03-2018 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain GBCGDNIH2_RS03900 3075b50cb528b1983fa0676045310b6b 590 Gene3D G3DSA:3.30.565.10 425 576 2.4E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS03900 3075b50cb528b1983fa0676045310b6b 590 SUPERFAMILY SSF55874 428 568 6.02E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS03170 3444b3badc48dce5fa3ca310f714ec8c 917 Pfam PF07516 SecA Wing and Scaffold domain 613 823 3.2E-63 T 29-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 GBCGDNIH2_RS03170 3444b3badc48dce5fa3ca310f714ec8c 917 Hamap MF_01382 Protein translocase subunit SecA [secA]. 5 826 20.038 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 GBCGDNIH2_RS03170 3444b3badc48dce5fa3ca310f714ec8c 917 PRINTS PR00906 SecA protein signature 328 350 1.1E-70 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 GBCGDNIH2_RS03170 3444b3badc48dce5fa3ca310f714ec8c 917 PRINTS PR00906 SecA protein signature 365 382 1.1E-70 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 GBCGDNIH2_RS03170 3444b3badc48dce5fa3ca310f714ec8c 917 PRINTS PR00906 SecA protein signature 402 415 1.1E-70 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 GBCGDNIH2_RS03170 3444b3badc48dce5fa3ca310f714ec8c 917 PRINTS PR00906 SecA protein signature 170 190 1.1E-70 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 GBCGDNIH2_RS03170 3444b3badc48dce5fa3ca310f714ec8c 917 PRINTS PR00906 SecA protein signature 117 127 1.1E-70 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 GBCGDNIH2_RS03170 3444b3badc48dce5fa3ca310f714ec8c 917 PRINTS PR00906 SecA protein signature 63 87 1.1E-70 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 GBCGDNIH2_RS03170 3444b3badc48dce5fa3ca310f714ec8c 917 PRINTS PR00906 SecA protein signature 101 115 1.1E-70 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 GBCGDNIH2_RS03170 3444b3badc48dce5fa3ca310f714ec8c 917 SUPERFAMILY SSF52540 406 613 1.48E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS03170 3444b3badc48dce5fa3ca310f714ec8c 917 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 28 811 0.0 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 GBCGDNIH2_RS03170 3444b3badc48dce5fa3ca310f714ec8c 917 SUPERFAMILY SSF52540 6 228 4.12E-86 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS03170 3444b3badc48dce5fa3ca310f714ec8c 917 SUPERFAMILY SSF52540 357 404 4.12E-86 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS03170 3444b3badc48dce5fa3ca310f714ec8c 917 SUPERFAMILY SSF81767 227 357 1.05E-41 T 29-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 GBCGDNIH2_RS03170 3444b3badc48dce5fa3ca310f714ec8c 917 Pfam PF07517 SecA DEAD-like domain 7 390 3.0E-133 T 29-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 GBCGDNIH2_RS03170 3444b3badc48dce5fa3ca310f714ec8c 917 Pfam PF02810 SEC-C motif 897 915 1.1E-9 T 29-03-2018 IPR004027 SEC-C motif GBCGDNIH2_RS03170 3444b3badc48dce5fa3ca310f714ec8c 917 SMART SM00958 228 347 1.4E-71 T 29-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 GBCGDNIH2_RS03170 3444b3badc48dce5fa3ca310f714ec8c 917 Gene3D G3DSA:3.40.50.300 9 271 5.2E-56 T 29-03-2018 GBCGDNIH2_RS03170 3444b3badc48dce5fa3ca310f714ec8c 917 Gene3D G3DSA:3.40.50.300 296 405 6.4E-8 T 29-03-2018 GBCGDNIH2_RS03170 3444b3badc48dce5fa3ca310f714ec8c 917 ProSitePatterns PS01312 SecA family signature. 489 504 - T 29-03-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 GBCGDNIH2_RS03170 3444b3badc48dce5fa3ca310f714ec8c 917 Pfam PF01043 SecA preprotein cross-linking domain 232 347 3.1E-38 T 29-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 GBCGDNIH2_RS03170 3444b3badc48dce5fa3ca310f714ec8c 917 SMART SM00957 6 391 2.4E-295 T 29-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 GBCGDNIH2_RS03170 3444b3badc48dce5fa3ca310f714ec8c 917 SUPERFAMILY SSF81886 615 834 1.44E-76 T 29-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 GBCGDNIH2_RS03170 3444b3badc48dce5fa3ca310f714ec8c 917 SUPERFAMILY SSF81886 893 905 1.44E-76 T 29-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 GBCGDNIH2_RS03170 3444b3badc48dce5fa3ca310f714ec8c 917 Gene3D G3DSA:1.10.3060.10 745 832 1.5E-20 T 29-03-2018 GBCGDNIH2_RS03170 3444b3badc48dce5fa3ca310f714ec8c 917 Gene3D G3DSA:1.10.3060.10 630 744 3.3E-31 T 29-03-2018 GBCGDNIH2_RS03170 3444b3badc48dce5fa3ca310f714ec8c 917 Gene3D G3DSA:3.40.50.300 406 629 4.4E-56 T 29-03-2018 GBCGDNIH2_RS08930 278291c268ae4859f1a51ee999e19562 98 Pfam PF09707 CRISPR-associated protein (Cas_Cas2CT1978) 5 94 1.1E-24 T 29-03-2018 IPR010152 CRISPR-associated protein Cas2 subtype GBCGDNIH2_RS08930 278291c268ae4859f1a51ee999e19562 98 TIGRFAM TIGR01873 cas_CT1978: CRISPR-associated endoribonuclease Cas2, subtype I-E/ECOLI 6 94 5.9E-25 T 29-03-2018 IPR010152 CRISPR-associated protein Cas2 subtype GBCGDNIH2_RS08160 bff5406c0fb4e257fc7199442023ce19 990 Pfam PF00535 Glycosyl transferase family 2 361 470 1.5E-18 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 GBCGDNIH2_RS08160 bff5406c0fb4e257fc7199442023ce19 990 SUPERFAMILY SSF53756 620 987 6.15E-23 T 29-03-2018 GBCGDNIH2_RS08160 bff5406c0fb4e257fc7199442023ce19 990 SUPERFAMILY SSF53448 357 578 5.25E-45 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS08160 bff5406c0fb4e257fc7199442023ce19 990 Pfam PF13692 Glycosyl transferases group 1 810 953 1.4E-21 T 29-03-2018 GBCGDNIH2_RS08160 bff5406c0fb4e257fc7199442023ce19 990 Gene3D G3DSA:3.90.550.10 332 632 1.2E-44 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS08160 bff5406c0fb4e257fc7199442023ce19 990 Gene3D G3DSA:3.40.50.2000 782 973 6.6E-16 T 29-03-2018 GBCGDNIH2_RS10835 8d026771a01bbd24bbb82d506488d45c 340 Gene3D G3DSA:3.40.50.720 1 140 1.8E-33 T 29-03-2018 GBCGDNIH2_RS10835 8d026771a01bbd24bbb82d506488d45c 340 SUPERFAMILY SSF55347 129 319 2.74E-74 T 29-03-2018 GBCGDNIH2_RS10835 8d026771a01bbd24bbb82d506488d45c 340 SMART SM00859 4 120 3.4E-44 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 GBCGDNIH2_RS10835 8d026771a01bbd24bbb82d506488d45c 340 PIRSF PIRSF000148 2 337 8.8E-131 T 29-03-2018 GBCGDNIH2_RS10835 8d026771a01bbd24bbb82d506488d45c 340 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 139 318 1.2E-54 T 29-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 GBCGDNIH2_RS10835 8d026771a01bbd24bbb82d506488d45c 340 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 2 332 35.888 T 29-03-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 GBCGDNIH2_RS10835 8d026771a01bbd24bbb82d506488d45c 340 Gene3D G3DSA:3.30.360.10 141 315 2.3E-73 T 29-03-2018 GBCGDNIH2_RS10835 8d026771a01bbd24bbb82d506488d45c 340 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 4 119 9.3E-31 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 GBCGDNIH2_RS10835 8d026771a01bbd24bbb82d506488d45c 340 SUPERFAMILY SSF51735 3 157 1.85E-49 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS10835 8d026771a01bbd24bbb82d506488d45c 340 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 4 333 3.3E-134 T 29-03-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 GBCGDNIH2_RS09775 3407db71d1d8cfd2c2d041f524057e88 74 PRINTS PR00124 ATP synthase C subunit signature 9 28 4.2E-28 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 GBCGDNIH2_RS09775 3407db71d1d8cfd2c2d041f524057e88 74 PRINTS PR00124 ATP synthase C subunit signature 47 72 4.2E-28 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 GBCGDNIH2_RS09775 3407db71d1d8cfd2c2d041f524057e88 74 PRINTS PR00124 ATP synthase C subunit signature 30 45 4.2E-28 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 GBCGDNIH2_RS09775 3407db71d1d8cfd2c2d041f524057e88 74 ProSitePatterns PS00605 ATP synthase c subunit signature. 37 58 - T 29-03-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 GBCGDNIH2_RS09775 3407db71d1d8cfd2c2d041f524057e88 74 SUPERFAMILY SSF81333 4 74 4.58E-18 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 GBCGDNIH2_RS09775 3407db71d1d8cfd2c2d041f524057e88 74 Pfam PF00137 ATP synthase subunit C 9 71 5.3E-12 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 GBCGDNIH2_RS09775 3407db71d1d8cfd2c2d041f524057e88 74 Gene3D G3DSA:1.20.20.10 3 74 9.1E-22 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 GBCGDNIH2_RS09775 3407db71d1d8cfd2c2d041f524057e88 74 Hamap MF_01396 ATP synthase subunit c [atpH]. 4 72 14.593 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 GBCGDNIH2_RS01120 8bbb41454c3a2e8a774449706abb018c 668 Gene3D G3DSA:3.40.50.920 522 660 1.4E-31 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 GBCGDNIH2_RS01120 8bbb41454c3a2e8a774449706abb018c 668 ProSitePatterns PS00801 Transketolase signature 1. 40 59 - T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 GBCGDNIH2_RS01120 8bbb41454c3a2e8a774449706abb018c 668 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 14 659 43.526 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 GBCGDNIH2_RS01120 8bbb41454c3a2e8a774449706abb018c 668 SUPERFAMILY SSF52922 518 658 2.09E-25 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 GBCGDNIH2_RS01120 8bbb41454c3a2e8a774449706abb018c 668 ProSitePatterns PS00802 Transketolase signature 2. 445 461 - T 29-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 GBCGDNIH2_RS01120 8bbb41454c3a2e8a774449706abb018c 668 Gene3D G3DSA:3.40.50.970 5 325 1.6E-80 T 29-03-2018 GBCGDNIH2_RS01120 8bbb41454c3a2e8a774449706abb018c 668 Gene3D G3DSA:3.40.50.970 326 511 1.8E-44 T 29-03-2018 GBCGDNIH2_RS01120 8bbb41454c3a2e8a774449706abb018c 668 SUPERFAMILY SSF52518 336 531 1.59E-58 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold GBCGDNIH2_RS01120 8bbb41454c3a2e8a774449706abb018c 668 Pfam PF02779 Transketolase, pyrimidine binding domain 339 499 6.7E-40 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain GBCGDNIH2_RS01120 8bbb41454c3a2e8a774449706abb018c 668 SMART SM00861 339 504 1.2E-64 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain GBCGDNIH2_RS01120 8bbb41454c3a2e8a774449706abb018c 668 Pfam PF02780 Transketolase, C-terminal domain 522 650 1.3E-20 T 29-03-2018 IPR033248 Transketolase, C-terminal domain GBCGDNIH2_RS01120 8bbb41454c3a2e8a774449706abb018c 668 SUPERFAMILY SSF52518 10 210 3.3E-77 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold GBCGDNIH2_RS01120 8bbb41454c3a2e8a774449706abb018c 668 SUPERFAMILY SSF52518 255 401 3.3E-77 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold GBCGDNIH2_RS01120 8bbb41454c3a2e8a774449706abb018c 668 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 18 657 3.9E-229 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 GBCGDNIH2_RS01120 8bbb41454c3a2e8a774449706abb018c 668 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 15 296 9.6E-114 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 GBCGDNIH2_RS02560 02999c13262eb4f8bc288413bcbec597 339 PIRSF PIRSF001619 14 338 6.7E-132 T 29-03-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 GBCGDNIH2_RS02560 02999c13262eb4f8bc288413bcbec597 339 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 246 336 2.9E-19 T 29-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 GBCGDNIH2_RS02560 02999c13262eb4f8bc288413bcbec597 339 SMART SM00729 69 281 2.5E-39 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 GBCGDNIH2_RS02560 02999c13262eb4f8bc288413bcbec597 339 SUPERFAMILY SSF102114 31 338 4.71E-93 T 29-03-2018 GBCGDNIH2_RS02560 02999c13262eb4f8bc288413bcbec597 339 Gene3D G3DSA:3.20.20.70 30 339 1.9E-60 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS02560 02999c13262eb4f8bc288413bcbec597 339 TIGRFAM TIGR00433 bioB: biotin synthase 41 336 1.4E-121 T 29-03-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 GBCGDNIH2_RS02560 02999c13262eb4f8bc288413bcbec597 339 SMART SM00876 246 338 2.0E-46 T 29-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 GBCGDNIH2_RS02560 02999c13262eb4f8bc288413bcbec597 339 Hamap MF_01694 Biotin synthase [bioB]. 31 339 41.756 T 29-03-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 GBCGDNIH2_RS02560 02999c13262eb4f8bc288413bcbec597 339 Pfam PF04055 Radical SAM superfamily 76 224 1.0E-13 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 GBCGDNIH2_RS05490 145af5a996695ea359cb1f68047fdc24 322 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 4 322 8.3E-126 T 29-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 GBCGDNIH2_RS05490 145af5a996695ea359cb1f68047fdc24 322 SUPERFAMILY SSF53901 5 322 1.03E-69 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 GBCGDNIH2_RS05490 145af5a996695ea359cb1f68047fdc24 322 Gene3D G3DSA:3.40.47.10 2 161 5.2E-38 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 GBCGDNIH2_RS05490 145af5a996695ea359cb1f68047fdc24 322 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 2 322 69.458 T 29-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 GBCGDNIH2_RS05490 145af5a996695ea359cb1f68047fdc24 322 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 233 322 2.5E-37 T 29-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 GBCGDNIH2_RS05490 145af5a996695ea359cb1f68047fdc24 322 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 107 189 1.1E-30 T 29-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 GBCGDNIH2_RS05490 145af5a996695ea359cb1f68047fdc24 322 Gene3D G3DSA:3.40.47.10 162 322 4.8E-43 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 GBCGDNIH2_RS05375 c99f6eb6f0f2d377f89e508339944d8b 258 SUPERFAMILY SSF69065 18 182 6.28E-41 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 GBCGDNIH2_RS05375 c99f6eb6f0f2d377f89e508339944d8b 258 Pfam PF14622 Ribonuclease-III-like 34 166 7.7E-29 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 GBCGDNIH2_RS05375 c99f6eb6f0f2d377f89e508339944d8b 258 Hamap MF_00104 Ribonuclease 3 [rnc]. 19 243 26.308 T 29-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 GBCGDNIH2_RS05375 c99f6eb6f0f2d377f89e508339944d8b 258 ProSitePatterns PS00517 Ribonuclease III family signature. 65 73 - T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 GBCGDNIH2_RS05375 c99f6eb6f0f2d377f89e508339944d8b 258 Gene3D G3DSA:1.10.1520.10 5 172 2.8E-39 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 GBCGDNIH2_RS05375 c99f6eb6f0f2d377f89e508339944d8b 258 Gene3D G3DSA:3.30.160.20 173 251 2.9E-18 T 29-03-2018 GBCGDNIH2_RS05375 c99f6eb6f0f2d377f89e508339944d8b 258 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 25 245 4.0E-64 T 29-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 GBCGDNIH2_RS05375 c99f6eb6f0f2d377f89e508339944d8b 258 SMART SM00535 34 176 9.3E-41 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 GBCGDNIH2_RS05375 c99f6eb6f0f2d377f89e508339944d8b 258 SUPERFAMILY SSF54768 137 248 9.9E-25 T 29-03-2018 GBCGDNIH2_RS05375 c99f6eb6f0f2d377f89e508339944d8b 258 SMART SM00358 181 247 3.8E-22 T 29-03-2018 IPR014720 Double-stranded RNA-binding domain GBCGDNIH2_RS05375 c99f6eb6f0f2d377f89e508339944d8b 258 Pfam PF00035 Double-stranded RNA binding motif 181 243 6.1E-12 T 29-03-2018 IPR014720 Double-stranded RNA-binding domain GBCGDNIH2_RS03485 5b9c4e489e75e0d0569c0eb4049099bb 89 SUPERFAMILY SSF47729 1 89 1.0E-22 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 GBCGDNIH2_RS03485 5b9c4e489e75e0d0569c0eb4049099bb 89 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 4.6E-8 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 GBCGDNIH2_RS03485 5b9c4e489e75e0d0569c0eb4049099bb 89 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 4.6E-8 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 GBCGDNIH2_RS03485 5b9c4e489e75e0d0569c0eb4049099bb 89 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 4.6E-8 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 GBCGDNIH2_RS03485 5b9c4e489e75e0d0569c0eb4049099bb 89 Pfam PF00216 Bacterial DNA-binding protein 1 89 2.5E-24 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 GBCGDNIH2_RS03485 5b9c4e489e75e0d0569c0eb4049099bb 89 SMART SM00411 1 89 7.4E-13 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 GBCGDNIH2_RS03485 5b9c4e489e75e0d0569c0eb4049099bb 89 Gene3D G3DSA:4.10.520.10 1 89 4.3E-24 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 GBCGDNIH2_RS09510 095cbe4651eaad1b912984e2359425c7 315 SUPERFAMILY SSF160240 223 299 3.66E-9 T 29-03-2018 GBCGDNIH2_RS09510 095cbe4651eaad1b912984e2359425c7 315 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 10 299 4.5E-41 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 GBCGDNIH2_RS09510 095cbe4651eaad1b912984e2359425c7 315 Gene3D G3DSA:1.20.1510.10 6 218 4.5E-31 T 29-03-2018 GBCGDNIH2_RS09510 095cbe4651eaad1b912984e2359425c7 315 Gene3D G3DSA:3.30.70.1350 219 309 7.1E-10 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain GBCGDNIH2_RS09510 095cbe4651eaad1b912984e2359425c7 315 SUPERFAMILY SSF161111 6 220 3.79E-39 T 29-03-2018 GBCGDNIH2_RS09510 095cbe4651eaad1b912984e2359425c7 315 Pfam PF01545 Cation efflux family 12 218 1.2E-31 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 GBCGDNIH2_RS03100 077145f12a4585c49dbf1311f9043388 352 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 222 238 - T 29-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 GBCGDNIH2_RS03100 077145f12a4585c49dbf1311f9043388 352 Pfam PF03462 PCRF domain 12 198 7.4E-62 T 29-03-2018 IPR005139 Peptide chain release factor GO:0006415 GBCGDNIH2_RS03100 077145f12a4585c49dbf1311f9043388 352 Gene3D G3DSA:3.30.160.20 203 285 5.6E-33 T 29-03-2018 GBCGDNIH2_RS03100 077145f12a4585c49dbf1311f9043388 352 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 3 351 37.654 T 29-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 GBCGDNIH2_RS03100 077145f12a4585c49dbf1311f9043388 352 Gene3D G3DSA:1.20.58.410 1 96 3.0E-8 T 29-03-2018 GBCGDNIH2_RS03100 077145f12a4585c49dbf1311f9043388 352 Pfam PF00472 RF-1 domain 206 315 4.0E-41 T 29-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 GBCGDNIH2_RS03100 077145f12a4585c49dbf1311f9043388 352 SMART SM00937 58 173 4.8E-49 T 29-03-2018 IPR005139 Peptide chain release factor GO:0006415 GBCGDNIH2_RS03100 077145f12a4585c49dbf1311f9043388 352 SUPERFAMILY SSF75620 26 347 4.84E-125 T 29-03-2018 GBCGDNIH2_RS03100 077145f12a4585c49dbf1311f9043388 352 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 3 349 2.0E-144 T 29-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 GBCGDNIH2_RS01035 ff04a5dc2c16b6bf834c92aab1b89987 207 Pfam PF05494 MlaC protein 48 201 4.3E-32 T 29-03-2018 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC GBCGDNIH2_RS01035 ff04a5dc2c16b6bf834c92aab1b89987 207 Gene3D G3DSA:3.10.450.50 72 173 3.2E-11 T 29-03-2018 GBCGDNIH2_RS10270 8e0369bcedb42247f1eb88e2b91e5691 85 Gene3D G3DSA:2.60.260.40 26 76 8.3E-19 T 29-03-2018 GBCGDNIH2_RS10270 8e0369bcedb42247f1eb88e2b91e5691 85 Pfam PF10276 Zinc-finger domain 38 73 1.4E-14 T 29-03-2018 IPR019401 Zinc finger, CHCC-type Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS00155 70d913aaee7fcd5a2951d1e5c33459ed 389 Gene3D G3DSA:3.40.47.10 1 242 6.1E-36 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 GBCGDNIH2_RS00155 70d913aaee7fcd5a2951d1e5c33459ed 389 SMART SM00825 Beta-ketoacyl synthase 57 389 1.3E-9 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain GBCGDNIH2_RS00155 70d913aaee7fcd5a2951d1e5c33459ed 389 SUPERFAMILY SSF53901 1 234 5.76E-34 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 GBCGDNIH2_RS00155 70d913aaee7fcd5a2951d1e5c33459ed 389 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 70 234 1.4E-21 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal GBCGDNIH2_RS00155 70d913aaee7fcd5a2951d1e5c33459ed 389 SUPERFAMILY SSF53901 208 388 4.37E-47 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 GBCGDNIH2_RS00155 70d913aaee7fcd5a2951d1e5c33459ed 389 Gene3D G3DSA:3.40.47.10 244 389 1.4E-44 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 GBCGDNIH2_RS00155 70d913aaee7fcd5a2951d1e5c33459ed 389 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 237 347 9.7E-30 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal GBCGDNIH2_RS00155 70d913aaee7fcd5a2951d1e5c33459ed 389 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 151 167 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site GBCGDNIH2_RS06735 c4554d490d709fad68b68d9e0d4f35d3 423 PRINTS PR00981 Seryl-tRNA synthetase signature 274 287 9.0E-30 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 GBCGDNIH2_RS06735 c4554d490d709fad68b68d9e0d4f35d3 423 PRINTS PR00981 Seryl-tRNA synthetase signature 331 347 9.0E-30 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 GBCGDNIH2_RS06735 c4554d490d709fad68b68d9e0d4f35d3 423 PRINTS PR00981 Seryl-tRNA synthetase signature 349 365 9.0E-30 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 GBCGDNIH2_RS06735 c4554d490d709fad68b68d9e0d4f35d3 423 PRINTS PR00981 Seryl-tRNA synthetase signature 314 327 9.0E-30 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 GBCGDNIH2_RS06735 c4554d490d709fad68b68d9e0d4f35d3 423 PRINTS PR00981 Seryl-tRNA synthetase signature 262 274 9.0E-30 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 GBCGDNIH2_RS06735 c4554d490d709fad68b68d9e0d4f35d3 423 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 106 3.7E-22 T 29-03-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 GBCGDNIH2_RS06735 c4554d490d709fad68b68d9e0d4f35d3 423 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 225 398 2.7E-31 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 GBCGDNIH2_RS06735 c4554d490d709fad68b68d9e0d4f35d3 423 PIRSF PIRSF001529 1 423 1.6E-153 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 GBCGDNIH2_RS06735 c4554d490d709fad68b68d9e0d4f35d3 423 Gene3D G3DSA:3.30.930.10 105 423 2.7E-91 T 29-03-2018 GBCGDNIH2_RS06735 c4554d490d709fad68b68d9e0d4f35d3 423 SUPERFAMILY SSF46589 1 112 1.62E-21 T 29-03-2018 IPR010978 tRNA-binding arm GO:0000166 GBCGDNIH2_RS06735 c4554d490d709fad68b68d9e0d4f35d3 423 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 420 38.063 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 GBCGDNIH2_RS06735 c4554d490d709fad68b68d9e0d4f35d3 423 SUPERFAMILY SSF55681 116 417 2.93E-93 T 29-03-2018 GBCGDNIH2_RS06735 c4554d490d709fad68b68d9e0d4f35d3 423 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 415 2.5E-144 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 GBCGDNIH2_RS06735 c4554d490d709fad68b68d9e0d4f35d3 423 Gene3D G3DSA:1.10.287.40 3 104 2.8E-19 T 29-03-2018 GBCGDNIH2_RS05755 2bf5f8110df8706c1d6cf808107ac283 327 Pfam PF03524 Conjugal transfer protein 96 320 2.7E-56 T 29-03-2018 IPR010258 Conjugal transfer, TrbG/VirB9/CagX GBCGDNIH2_RS05755 2bf5f8110df8706c1d6cf808107ac283 327 TIGRFAM TIGR02775 TrbG_Ti: P-type conjugative transfer protein TrbG 145 308 1.4E-56 T 29-03-2018 IPR014142 P-type conjugative transfer protein TrbG GBCGDNIH2_RS12180 b300ac399fb5005b55693d506d7ebb99 577 Gene3D G3DSA:3.40.50.1220 196 367 3.3E-35 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain GBCGDNIH2_RS12180 b300ac399fb5005b55693d506d7ebb99 577 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 196 322 1.0E-27 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 GBCGDNIH2_RS12180 b300ac399fb5005b55693d506d7ebb99 577 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 384 529 2.7E-39 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 GBCGDNIH2_RS12180 b300ac399fb5005b55693d506d7ebb99 577 Gene3D G3DSA:3.40.50.970 368 548 1.0E-39 T 29-03-2018 GBCGDNIH2_RS12180 b300ac399fb5005b55693d506d7ebb99 577 SUPERFAMILY SSF52518 360 562 3.79E-61 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold GBCGDNIH2_RS12180 b300ac399fb5005b55693d506d7ebb99 577 SUPERFAMILY SSF52467 184 352 6.31E-43 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain GBCGDNIH2_RS12180 b300ac399fb5005b55693d506d7ebb99 577 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 421 440 - T 29-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 GBCGDNIH2_RS12180 b300ac399fb5005b55693d506d7ebb99 577 Gene3D G3DSA:3.40.50.970 1 195 1.8E-45 T 29-03-2018 GBCGDNIH2_RS12180 b300ac399fb5005b55693d506d7ebb99 577 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 172 1.6E-43 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 GBCGDNIH2_RS12180 b300ac399fb5005b55693d506d7ebb99 577 SUPERFAMILY SSF52518 4 176 3.84E-45 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold GBCGDNIH2_RS05650 3a3b63173c997bfdc8ea46c6dc36261e 128 Gene3D G3DSA:2.60.120.10 14 117 1.4E-12 T 29-03-2018 IPR014710 RmlC-like jelly roll fold GBCGDNIH2_RS05650 3a3b63173c997bfdc8ea46c6dc36261e 128 SUPERFAMILY SSF51182 39 111 4.74E-9 T 29-03-2018 IPR011051 RmlC-like cupin domain GBCGDNIH2_RS09320 163039c4a8651c7e680fe3f8e981d37e 383 PIRSF PIRSF001112 1 383 9.4E-114 T 29-03-2018 IPR016292 Epoxide hydrolase GO:0033961 KEGG: 00980+3.3.2.9|Reactome: R-HSA-211945 GBCGDNIH2_RS09320 163039c4a8651c7e680fe3f8e981d37e 383 Pfam PF06441 Epoxide hydrolase N terminus 5 110 1.4E-31 T 29-03-2018 IPR010497 Epoxide hydrolase, N-terminal KEGG: 00980+3.3.2.9|Reactome: R-HSA-211945 GBCGDNIH2_RS09320 163039c4a8651c7e680fe3f8e981d37e 383 Gene3D G3DSA:3.40.50.1820 2 383 7.4E-64 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS09320 163039c4a8651c7e680fe3f8e981d37e 383 SUPERFAMILY SSF53474 3 381 1.7E-86 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS09320 163039c4a8651c7e680fe3f8e981d37e 383 PRINTS PR00412 Epoxide hydrolase signature 176 189 2.0E-10 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 GBCGDNIH2_RS09320 163039c4a8651c7e680fe3f8e981d37e 383 PRINTS PR00412 Epoxide hydrolase signature 101 119 2.0E-10 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 GBCGDNIH2_RS09320 163039c4a8651c7e680fe3f8e981d37e 383 PRINTS PR00412 Epoxide hydrolase signature 130 145 2.0E-10 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 GBCGDNIH2_RS09320 163039c4a8651c7e680fe3f8e981d37e 383 PRINTS PR00412 Epoxide hydrolase signature 357 379 2.0E-10 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 GBCGDNIH2_RS10550 6de1877f6d87643d29486cda6e5806f2 209 Pfam PF02224 Cytidylate kinase 5 202 1.5E-50 T 29-03-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 GBCGDNIH2_RS10550 6de1877f6d87643d29486cda6e5806f2 209 SUPERFAMILY SSF52540 2 206 2.08E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS10550 6de1877f6d87643d29486cda6e5806f2 209 TIGRFAM TIGR00017 cmk: cytidylate kinase 1 196 6.6E-47 T 29-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 GBCGDNIH2_RS10550 6de1877f6d87643d29486cda6e5806f2 209 Hamap MF_00238 Cytidylate kinase [cmk]. 3 207 29.693 T 29-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 GBCGDNIH2_RS10550 6de1877f6d87643d29486cda6e5806f2 209 Gene3D G3DSA:3.40.50.300 1 206 4.7E-42 T 29-03-2018 GBCGDNIH2_RS00355 3608e456771fd41df34dfdeab865527e 262 SMART SM00893 3 188 0.005 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 GBCGDNIH2_RS00355 3608e456771fd41df34dfdeab865527e 262 Gene3D G3DSA:3.40.50.620 13 245 4.6E-29 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GBCGDNIH2_RS00355 3608e456771fd41df34dfdeab865527e 262 Pfam PF01012 Electron transfer flavoprotein domain 25 182 1.5E-22 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 GBCGDNIH2_RS00355 3608e456771fd41df34dfdeab865527e 262 SUPERFAMILY SSF52402 26 239 1.22E-22 T 29-03-2018 GBCGDNIH2_RS03210 1bfa225cd10e213008aed8676216cad2 204 SMART SM00271 132 190 4.9E-10 T 29-03-2018 IPR001623 DnaJ domain GBCGDNIH2_RS03210 1bfa225cd10e213008aed8676216cad2 204 SUPERFAMILY SSF46565 134 186 3.27E-13 T 29-03-2018 IPR001623 DnaJ domain GBCGDNIH2_RS03210 1bfa225cd10e213008aed8676216cad2 204 Gene3D G3DSA:1.10.287.110 37 188 2.0E-13 T 29-03-2018 IPR001623 DnaJ domain GBCGDNIH2_RS03210 1bfa225cd10e213008aed8676216cad2 204 PRINTS PR00625 DnaJ domain signature 153 168 8.7E-5 T 29-03-2018 IPR001623 DnaJ domain GBCGDNIH2_RS03210 1bfa225cd10e213008aed8676216cad2 204 PRINTS PR00625 DnaJ domain signature 170 190 8.7E-5 T 29-03-2018 IPR001623 DnaJ domain GBCGDNIH2_RS03210 1bfa225cd10e213008aed8676216cad2 204 Pfam PF00226 DnaJ domain 137 186 7.0E-11 T 29-03-2018 IPR001623 DnaJ domain GBCGDNIH2_RS11420 6f40d36e20940ec00ec262a1cf76f18f 254 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 211 225 - T 29-03-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 GBCGDNIH2_RS11420 6f40d36e20940ec00ec262a1cf76f18f 254 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 83 95 - T 29-03-2018 IPR020583 Inositol monophosphatase, metal-binding site GBCGDNIH2_RS11420 6f40d36e20940ec00ec262a1cf76f18f 254 Gene3D G3DSA:3.30.540.10 1 148 1.2E-42 T 29-03-2018 GBCGDNIH2_RS11420 6f40d36e20940ec00ec262a1cf76f18f 254 PRINTS PR00377 Inositol monophosphatase superfamily signature 38 58 1.2E-13 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 GBCGDNIH2_RS11420 6f40d36e20940ec00ec262a1cf76f18f 254 PRINTS PR00377 Inositol monophosphatase superfamily signature 83 99 1.2E-13 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 GBCGDNIH2_RS11420 6f40d36e20940ec00ec262a1cf76f18f 254 PRINTS PR00377 Inositol monophosphatase superfamily signature 60 76 1.2E-13 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 GBCGDNIH2_RS11420 6f40d36e20940ec00ec262a1cf76f18f 254 PRINTS PR00377 Inositol monophosphatase superfamily signature 208 232 1.2E-13 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 GBCGDNIH2_RS11420 6f40d36e20940ec00ec262a1cf76f18f 254 TIGRFAM TIGR01331 bisphos_cysQ: 3'(2'),5'-bisphosphate nucleotidase 11 250 1.8E-76 T 29-03-2018 IPR006240 3(2),5 -bisphosphate nucleotidase, bacterial GO:0000287|GO:0016020 KEGG: 00920+3.1.3.7 GBCGDNIH2_RS11420 6f40d36e20940ec00ec262a1cf76f18f 254 SUPERFAMILY SSF56655 5 249 1.83E-72 T 29-03-2018 GBCGDNIH2_RS11420 6f40d36e20940ec00ec262a1cf76f18f 254 Pfam PF00459 Inositol monophosphatase family 7 237 2.8E-50 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 GBCGDNIH2_RS11420 6f40d36e20940ec00ec262a1cf76f18f 254 Gene3D G3DSA:3.40.190.80 149 253 1.3E-29 T 29-03-2018 GBCGDNIH2_RS00095 aed1995673f11baff0a35c5b750b1ec6 444 TIGRFAM TIGR01197 nramp: metal ion transporter, metal ion (Mn2+/Fe2+) transporter (Nramp) family 40 401 1.4E-93 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 GBCGDNIH2_RS00095 aed1995673f11baff0a35c5b750b1ec6 444 Hamap MF_00221 Divalent metal cation transporter MntH [mntH]. 28 433 35.925 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 GBCGDNIH2_RS00095 aed1995673f11baff0a35c5b750b1ec6 444 Pfam PF01566 Natural resistance-associated macrophage protein 58 407 3.9E-124 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 GBCGDNIH2_RS00095 aed1995673f11baff0a35c5b750b1ec6 444 PRINTS PR00447 Natural resistance-associated macrophage protein signature 145 164 4.7E-34 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 GBCGDNIH2_RS00095 aed1995673f11baff0a35c5b750b1ec6 444 PRINTS PR00447 Natural resistance-associated macrophage protein signature 117 143 4.7E-34 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 GBCGDNIH2_RS00095 aed1995673f11baff0a35c5b750b1ec6 444 PRINTS PR00447 Natural resistance-associated macrophage protein signature 220 243 4.7E-34 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 GBCGDNIH2_RS00095 aed1995673f11baff0a35c5b750b1ec6 444 PRINTS PR00447 Natural resistance-associated macrophage protein signature 323 342 4.7E-34 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 GBCGDNIH2_RS00095 aed1995673f11baff0a35c5b750b1ec6 444 PRINTS PR00447 Natural resistance-associated macrophage protein signature 170 191 4.7E-34 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 GBCGDNIH2_RS02790 bbdf3d657a0b6c7b064d681dee082e83 230 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 1 228 43.373 T 29-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 GBCGDNIH2_RS02790 bbdf3d657a0b6c7b064d681dee082e83 230 Gene3D G3DSA:3.40.50.790 67 148 6.6E-35 T 29-03-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich GBCGDNIH2_RS02790 bbdf3d657a0b6c7b064d681dee082e83 230 SUPERFAMILY SSF56808 5 225 4.32E-83 T 29-03-2018 IPR023674 Ribosomal protein L1-like GBCGDNIH2_RS02790 bbdf3d657a0b6c7b064d681dee082e83 230 Gene3D G3DSA:3.30.190.20 149 227 1.9E-22 T 29-03-2018 GBCGDNIH2_RS02790 bbdf3d657a0b6c7b064d681dee082e83 230 Pfam PF00687 Ribosomal protein L1p/L10e family 31 219 3.3E-54 T 29-03-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein GBCGDNIH2_RS02790 bbdf3d657a0b6c7b064d681dee082e83 230 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 227 2.5E-100 T 29-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 GBCGDNIH2_RS02790 bbdf3d657a0b6c7b064d681dee082e83 230 ProSitePatterns PS01199 Ribosomal protein L1 signature. 119 138 - T 29-03-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02790 bbdf3d657a0b6c7b064d681dee082e83 230 PIRSF PIRSF002155 1 226 1.4E-78 T 29-03-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS10325 16d10605eb7321af85af488b7660b450 313 Pfam PF02574 Homocysteine S-methyltransferase 15 307 5.1E-73 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 GBCGDNIH2_RS10325 16d10605eb7321af85af488b7660b450 313 PIRSF PIRSF037505 242 312 0.028 T 29-03-2018 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 Reactome: R-HSA-1614635 GBCGDNIH2_RS10325 16d10605eb7321af85af488b7660b450 313 PIRSF PIRSF037505 13 233 2.0E-4 T 29-03-2018 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 Reactome: R-HSA-1614635 GBCGDNIH2_RS10325 16d10605eb7321af85af488b7660b450 313 Gene3D G3DSA:3.20.20.330 3 313 2.3E-98 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 GBCGDNIH2_RS10325 16d10605eb7321af85af488b7660b450 313 SUPERFAMILY SSF82282 11 310 1.1E-80 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 GBCGDNIH2_RS07780 3ca299901398a72c6b04f1edd6a5da93 429 Gene3D G3DSA:1.20.1250.20 227 414 6.8E-10 T 29-03-2018 GBCGDNIH2_RS07780 3ca299901398a72c6b04f1edd6a5da93 429 Gene3D G3DSA:1.20.1250.20 24 204 1.8E-7 T 29-03-2018 GBCGDNIH2_RS07780 3ca299901398a72c6b04f1edd6a5da93 429 SUPERFAMILY SSF103473 21 398 1.07E-22 T 29-03-2018 IPR020846 Major facilitator superfamily domain GBCGDNIH2_RS07780 3ca299901398a72c6b04f1edd6a5da93 429 Pfam PF06779 Uncharacterised MFS-type transporter YbfB 35 393 3.4E-75 T 29-03-2018 IPR010645 Uncharacterised MFS-type transporter YbfB GBCGDNIH2_RS02505 f52b281208015e1d0be4b4b6bc9e0718 464 Pfam PF09856 Predicted transcriptional regulator (DUF2083) 305 458 5.4E-62 T 29-03-2018 IPR018653 Domain of unknown function DUF2083,transcriptional regulator GBCGDNIH2_RS02505 f52b281208015e1d0be4b4b6bc9e0718 464 PIRSF PIRSF019251 1 463 1.3E-177 T 29-03-2018 IPR026281 HTH-type transcriptional regulator RamB GO:0006355 GBCGDNIH2_RS02505 f52b281208015e1d0be4b4b6bc9e0718 464 Pfam PF06114 IrrE N-terminal-like domain 191 302 4.2E-12 T 29-03-2018 IPR010359 IrrE N-terminal-like domain GBCGDNIH2_RS02505 f52b281208015e1d0be4b4b6bc9e0718 464 Gene3D G3DSA:1.10.260.40 1 108 4.2E-14 T 29-03-2018 GBCGDNIH2_RS02505 f52b281208015e1d0be4b4b6bc9e0718 464 SMART SM00530 9 64 1.7E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 GBCGDNIH2_RS02505 f52b281208015e1d0be4b4b6bc9e0718 464 Pfam PF12844 Helix-turn-helix domain 7 63 1.3E-9 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 GBCGDNIH2_RS02505 f52b281208015e1d0be4b4b6bc9e0718 464 SUPERFAMILY SSF47413 1 68 3.22E-13 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GBCGDNIH2_RS11380 d58342371598806389e840204c212bfe 600 Pfam PF00557 Metallopeptidase family M24 314 527 1.0E-42 T 29-03-2018 IPR000994 Peptidase M24 GBCGDNIH2_RS11380 d58342371598806389e840204c212bfe 600 SUPERFAMILY SSF53092 174 288 3.92E-6 T 29-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal GBCGDNIH2_RS11380 d58342371598806389e840204c212bfe 600 Pfam PF01321 Creatinase/Prolidase N-terminal domain 15 130 2.5E-11 T 29-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 GBCGDNIH2_RS11380 d58342371598806389e840204c212bfe 600 SUPERFAMILY SSF53092 25 89 1.29E-6 T 29-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal GBCGDNIH2_RS11380 d58342371598806389e840204c212bfe 600 Gene3D G3DSA:3.40.350.10 159 294 2.9E-19 T 29-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal GBCGDNIH2_RS11380 d58342371598806389e840204c212bfe 600 Gene3D G3DSA:3.90.230.10 304 555 2.5E-58 T 29-03-2018 GBCGDNIH2_RS11380 d58342371598806389e840204c212bfe 600 Pfam PF16189 Creatinase/Prolidase N-terminal domain 152 310 6.0E-30 T 29-03-2018 GBCGDNIH2_RS11380 d58342371598806389e840204c212bfe 600 SUPERFAMILY SSF55920 309 562 8.9E-53 T 29-03-2018 IPR000994 Peptidase M24 GBCGDNIH2_RS11380 d58342371598806389e840204c212bfe 600 Gene3D G3DSA:3.40.350.10 7 150 1.6E-35 T 29-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal GBCGDNIH2_RS11380 d58342371598806389e840204c212bfe 600 Pfam PF16188 C-terminal region of peptidase_M24 536 596 6.3E-22 T 29-03-2018 IPR032416 Peptidase M24, C-terminal domain GBCGDNIH2_RS11615 97d57b4ea68aaf82e19131b4c7a5be15 471 SUPERFAMILY SSF47384 252 330 4.32E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GBCGDNIH2_RS11615 97d57b4ea68aaf82e19131b4c7a5be15 471 Gene3D G3DSA:1.10.287.130 258 313 1.6E-11 T 29-03-2018 GBCGDNIH2_RS11615 97d57b4ea68aaf82e19131b4c7a5be15 471 SMART SM00304 215 267 8.1E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 GBCGDNIH2_RS11615 97d57b4ea68aaf82e19131b4c7a5be15 471 Pfam PF00512 His Kinase A (phospho-acceptor) domain 269 331 7.5E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GBCGDNIH2_RS11615 97d57b4ea68aaf82e19131b4c7a5be15 471 PRINTS PR00344 Bacterial sensor protein C-terminal signature 433 451 4.4E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS11615 97d57b4ea68aaf82e19131b4c7a5be15 471 PRINTS PR00344 Bacterial sensor protein C-terminal signature 404 418 4.4E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS11615 97d57b4ea68aaf82e19131b4c7a5be15 471 PRINTS PR00344 Bacterial sensor protein C-terminal signature 457 470 4.4E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS11615 97d57b4ea68aaf82e19131b4c7a5be15 471 PRINTS PR00344 Bacterial sensor protein C-terminal signature 422 432 4.4E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS11615 97d57b4ea68aaf82e19131b4c7a5be15 471 SUPERFAMILY SSF55874 327 471 1.2E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS11615 97d57b4ea68aaf82e19131b4c7a5be15 471 SMART SM00388 268 332 3.5E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GBCGDNIH2_RS11615 97d57b4ea68aaf82e19131b4c7a5be15 471 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 373 471 3.4E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS11615 97d57b4ea68aaf82e19131b4c7a5be15 471 Pfam PF00672 HAMP domain 215 264 2.1E-6 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 GBCGDNIH2_RS11615 97d57b4ea68aaf82e19131b4c7a5be15 471 SMART SM00387 370 471 1.5E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS11615 97d57b4ea68aaf82e19131b4c7a5be15 471 Gene3D G3DSA:3.30.565.10 314 471 6.8E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS10845 efc90ef2544f7ef4e20a1f9577d26508 207 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 49 71 - T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 GBCGDNIH2_RS10845 efc90ef2544f7ef4e20a1f9577d26508 207 Pfam PF01066 CDP-alcohol phosphatidyltransferase 5 71 1.0E-14 T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 GBCGDNIH2_RS10845 efc90ef2544f7ef4e20a1f9577d26508 207 PIRSF PIRSF000847 1 193 2.0E-39 T 29-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 GBCGDNIH2_RS10845 efc90ef2544f7ef4e20a1f9577d26508 207 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 4 182 9.0E-37 T 29-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 GBCGDNIH2_RS00145 29381df566b1e9e6625e9c7db9c3a648 151 Gene3D G3DSA:3.10.129.10 2 147 1.4E-23 T 29-03-2018 GBCGDNIH2_RS00145 29381df566b1e9e6625e9c7db9c3a648 151 SUPERFAMILY SSF54637 12 147 1.81E-10 T 29-03-2018 IPR029069 HotDog domain GBCGDNIH2_RS01765 4429b9547ecd6f1e808fc75a2e18d491 244 TIGRFAM TIGR00164 PS_decarb_rel: phosphatidylserine decarboxylase homolog 41 241 1.4E-52 T 29-03-2018 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 GBCGDNIH2_RS01765 4429b9547ecd6f1e808fc75a2e18d491 244 Gene3D G3DSA:2.40.50.100 141 242 6.0E-4 T 29-03-2018 GBCGDNIH2_RS01765 4429b9547ecd6f1e808fc75a2e18d491 244 Hamap MF_00664 Phosphatidylserine decarboxylase proenzyme [psd]. 34 243 35.487 T 29-03-2018 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 GBCGDNIH2_RS01765 4429b9547ecd6f1e808fc75a2e18d491 244 Pfam PF02666 Phosphatidylserine decarboxylase 67 239 5.0E-29 T 29-03-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 GBCGDNIH2_RS01765 4429b9547ecd6f1e808fc75a2e18d491 244 Gene3D G3DSA:2.40.50.100 18 140 0.0094 T 29-03-2018 GBCGDNIH2_RS07170 e1c339e7d1f48120723c3625a43be907 454 Pfam PF04286 Protein of unknown function (DUF445) 84 448 2.5E-85 T 29-03-2018 IPR007383 Protein of unknown function DUF445 GBCGDNIH2_RS06795 2187dd353447c24c22e1f828c04e2447 448 ProSitePatterns PS00216 Sugar transport proteins signature 1. 299 315 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 GBCGDNIH2_RS06795 2187dd353447c24c22e1f828c04e2447 448 SUPERFAMILY SSF103473 4 442 3.4E-72 T 29-03-2018 IPR020846 Major facilitator superfamily domain GBCGDNIH2_RS06795 2187dd353447c24c22e1f828c04e2447 448 PRINTS PR00171 Sugar transporter signature 97 116 1.6E-29 T 29-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 GBCGDNIH2_RS06795 2187dd353447c24c22e1f828c04e2447 448 PRINTS PR00171 Sugar transporter signature 14 24 1.6E-29 T 29-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 GBCGDNIH2_RS06795 2187dd353447c24c22e1f828c04e2447 448 PRINTS PR00171 Sugar transporter signature 346 367 1.6E-29 T 29-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 GBCGDNIH2_RS06795 2187dd353447c24c22e1f828c04e2447 448 PRINTS PR00171 Sugar transporter signature 369 381 1.6E-29 T 29-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 GBCGDNIH2_RS06795 2187dd353447c24c22e1f828c04e2447 448 PRINTS PR00171 Sugar transporter signature 254 264 1.6E-29 T 29-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 GBCGDNIH2_RS06795 2187dd353447c24c22e1f828c04e2447 448 Gene3D G3DSA:1.20.1250.20 4 197 2.5E-34 T 29-03-2018 GBCGDNIH2_RS06795 2187dd353447c24c22e1f828c04e2447 448 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 4 441 4.2E-124 T 29-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 GBCGDNIH2_RS06795 2187dd353447c24c22e1f828c04e2447 448 Gene3D G3DSA:1.20.1250.20 219 448 8.0E-35 T 29-03-2018 GBCGDNIH2_RS06795 2187dd353447c24c22e1f828c04e2447 448 Pfam PF00083 Sugar (and other) transporter 7 443 1.1E-123 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 GBCGDNIH2_RS06795 2187dd353447c24c22e1f828c04e2447 448 ProSitePatterns PS00217 Sugar transport proteins signature 2. 102 127 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 GBCGDNIH2_RS03380 12cefca70aad7966157f8eb0ce291709 463 Gene3D G3DSA:3.40.1010.10 60 164 4.6E-12 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GBCGDNIH2_RS03380 12cefca70aad7966157f8eb0ce291709 463 TIGRFAM TIGR02469 CbiT: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit 291 411 1.4E-30 T 29-03-2018 IPR014008 Cobalamin biosynthesis, precorrin-6Y methyltransferase, CbiT subunit GO:0008276|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.196|MetaCyc: PWY-2201|MetaCyc: PWY-7377 GBCGDNIH2_RS03380 12cefca70aad7966157f8eb0ce291709 463 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 66 249 6.7E-14 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GBCGDNIH2_RS03380 12cefca70aad7966157f8eb0ce291709 463 Gene3D G3DSA:3.40.50.150 285 460 1.2E-29 T 29-03-2018 GBCGDNIH2_RS03380 12cefca70aad7966157f8eb0ce291709 463 SUPERFAMILY SSF53335 265 455 1.25E-29 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GBCGDNIH2_RS03380 12cefca70aad7966157f8eb0ce291709 463 SUPERFAMILY SSF53790 63 264 1.6E-33 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GBCGDNIH2_RS03380 12cefca70aad7966157f8eb0ce291709 463 Pfam PF02390 Putative methyltransferase 312 372 2.0E-4 T 29-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 GBCGDNIH2_RS03380 12cefca70aad7966157f8eb0ce291709 463 Gene3D G3DSA:3.30.950.10 165 272 9.3E-17 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GBCGDNIH2_RS03380 12cefca70aad7966157f8eb0ce291709 463 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 66 251 1.2E-35 T 29-03-2018 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 GBCGDNIH2_RS06760 d98151cf05ae4c134b592b2594efdb8a 231 Pfam PF02163 Peptidase family M50 131 171 4.0E-7 T 29-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 GBCGDNIH2_RS11945 0c304113c4194eecc3406dfe7f95dcad 275 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 10 96 3.7E-5 T 29-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal GBCGDNIH2_RS11945 0c304113c4194eecc3406dfe7f95dcad 275 SUPERFAMILY SSF48179 160 266 2.89E-26 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 GBCGDNIH2_RS11945 0c304113c4194eecc3406dfe7f95dcad 275 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 9 265 4.1E-63 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 GBCGDNIH2_RS11945 0c304113c4194eecc3406dfe7f95dcad 275 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 7 265 22.261 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 GBCGDNIH2_RS11945 0c304113c4194eecc3406dfe7f95dcad 275 Gene3D G3DSA:3.40.50.720 7 157 1.1E-21 T 29-03-2018 GBCGDNIH2_RS11945 0c304113c4194eecc3406dfe7f95dcad 275 SUPERFAMILY SSF51735 9 156 6.07E-23 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS11945 0c304113c4194eecc3406dfe7f95dcad 275 Gene3D G3DSA:1.10.3730.10 158 269 1.9E-28 T 29-03-2018 GBCGDNIH2_RS11945 0c304113c4194eecc3406dfe7f95dcad 275 PIRSF PIRSF000193 8 268 1.6E-52 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 GBCGDNIH2_RS11945 0c304113c4194eecc3406dfe7f95dcad 275 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 160 265 6.0E-28 T 29-03-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 GBCGDNIH2_RS03555 e9a21abfbb62579af26bafd1d8398fc6 280 Pfam PF00005 ABC transporter 60 204 1.4E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GBCGDNIH2_RS03555 e9a21abfbb62579af26bafd1d8398fc6 280 Gene3D G3DSA:3.40.50.300 42 276 6.3E-57 T 29-03-2018 GBCGDNIH2_RS03555 e9a21abfbb62579af26bafd1d8398fc6 280 SUPERFAMILY SSF52540 47 275 8.16E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS03555 e9a21abfbb62579af26bafd1d8398fc6 280 SMART SM00382 68 255 1.6E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS03555 e9a21abfbb62579af26bafd1d8398fc6 280 TIGRFAM TIGR04406 LPS_export_lptB: LPS export ABC transporter ATP-binding protein 46 280 3.0E-108 T 29-03-2018 IPR030921 LPS export ABC transporter, ATP-binding protein LptB GO:0043190|GO:0055085 GBCGDNIH2_RS03555 e9a21abfbb62579af26bafd1d8398fc6 280 ProSitePatterns PS00211 ABC transporters family signature. 177 191 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GBCGDNIH2_RS06220 99880bcde0e648eb506642884470bede 213 Pfam PF09998 Uncharacterized protein conserved in bacteria (DUF2239) 8 204 2.3E-79 T 29-03-2018 IPR018715 Protein of unknown function DUF2239 GBCGDNIH2_RS09955 66ade04b2e5ac9f42a25cd03cfd894ab 226 Gene3D G3DSA:1.10.10.10 141 221 6.7E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS09955 66ade04b2e5ac9f42a25cd03cfd894ab 226 SMART SM00421 159 216 1.7E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 GBCGDNIH2_RS09955 66ade04b2e5ac9f42a25cd03cfd894ab 226 SUPERFAMILY SSF46894 151 219 9.52E-15 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 GBCGDNIH2_RS09955 66ade04b2e5ac9f42a25cd03cfd894ab 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 176 1.6E-5 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 GBCGDNIH2_RS09955 66ade04b2e5ac9f42a25cd03cfd894ab 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 192 1.6E-5 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 GBCGDNIH2_RS09955 66ade04b2e5ac9f42a25cd03cfd894ab 226 SUPERFAMILY SSF52172 1 145 2.7E-26 T 29-03-2018 IPR011006 CheY-like superfamily GBCGDNIH2_RS09955 66ade04b2e5ac9f42a25cd03cfd894ab 226 SMART SM00448 1 132 3.8E-22 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GBCGDNIH2_RS09955 66ade04b2e5ac9f42a25cd03cfd894ab 226 Pfam PF00072 Response regulator receiver domain 39 129 4.6E-17 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GBCGDNIH2_RS09955 66ade04b2e5ac9f42a25cd03cfd894ab 226 Pfam PF00196 Bacterial regulatory proteins, luxR family 161 216 1.1E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 GBCGDNIH2_RS09955 66ade04b2e5ac9f42a25cd03cfd894ab 226 Gene3D G3DSA:3.40.50.2300 1 140 9.8E-29 T 29-03-2018 GBCGDNIH2_RS00180 322c1e30245f524f6905fb5435f25882 118 Pfam PF07977 FabA-like domain 20 76 4.5E-5 T 29-03-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 GBCGDNIH2_RS00180 322c1e30245f524f6905fb5435f25882 118 Gene3D G3DSA:3.10.129.10 17 107 6.1E-12 T 29-03-2018 GBCGDNIH2_RS00180 322c1e30245f524f6905fb5435f25882 118 SUPERFAMILY SSF54637 19 87 8.95E-11 T 29-03-2018 IPR029069 HotDog domain GBCGDNIH2_RS01535 498d7b0fc74c767292984dac57732551 268 Pfam PF12833 Helix-turn-helix domain 188 264 7.6E-21 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 GBCGDNIH2_RS01535 498d7b0fc74c767292984dac57732551 268 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 215 258 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 GBCGDNIH2_RS01535 498d7b0fc74c767292984dac57732551 268 SMART SM00342 181 262 9.5E-17 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 GBCGDNIH2_RS01535 498d7b0fc74c767292984dac57732551 268 Gene3D G3DSA:1.10.10.60 169 213 7.4E-7 T 29-03-2018 GBCGDNIH2_RS01535 498d7b0fc74c767292984dac57732551 268 Gene3D G3DSA:1.10.10.60 214 268 6.1E-9 T 29-03-2018 GBCGDNIH2_RS01535 498d7b0fc74c767292984dac57732551 268 Pfam PF02311 AraC-like ligand binding domain 28 96 8.4E-7 T 29-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 GBCGDNIH2_RS01535 498d7b0fc74c767292984dac57732551 268 SUPERFAMILY SSF46689 217 264 4.21E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 GBCGDNIH2_RS01535 498d7b0fc74c767292984dac57732551 268 SUPERFAMILY SSF51182 33 154 1.76E-13 T 29-03-2018 IPR011051 RmlC-like cupin domain GBCGDNIH2_RS01535 498d7b0fc74c767292984dac57732551 268 Gene3D G3DSA:2.60.120.10 9 168 4.7E-9 T 29-03-2018 IPR014710 RmlC-like jelly roll fold GBCGDNIH2_RS06885 16d7e88b989addcbf95474564cee2126 440 Gene3D G3DSA:3.40.50.800 334 440 4.2E-23 T 29-03-2018 IPR004154 Anticodon-binding GBCGDNIH2_RS06885 16d7e88b989addcbf95474564cee2126 440 SUPERFAMILY SSF52954 337 438 6.49E-24 T 29-03-2018 IPR004154 Anticodon-binding GBCGDNIH2_RS06885 16d7e88b989addcbf95474564cee2126 440 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 95 330 3.2E-35 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 GBCGDNIH2_RS06885 16d7e88b989addcbf95474564cee2126 440 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 223 1.7E-93 T 29-03-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 GBCGDNIH2_RS06885 16d7e88b989addcbf95474564cee2126 440 Pfam PF03129 Anticodon binding domain 349 438 7.8E-15 T 29-03-2018 IPR004154 Anticodon-binding GBCGDNIH2_RS06885 16d7e88b989addcbf95474564cee2126 440 Gene3D G3DSA:3.30.930.10 11 333 8.9E-85 T 29-03-2018 GBCGDNIH2_RS06885 16d7e88b989addcbf95474564cee2126 440 Hamap MF_01570 Proline--tRNA ligase [proS]. 1 438 59.584 T 29-03-2018 IPR023716 Proline-tRNA ligase, class IIa, type 2 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 GBCGDNIH2_RS06885 16d7e88b989addcbf95474564cee2126 440 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 4.8E-16 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 GBCGDNIH2_RS06885 16d7e88b989addcbf95474564cee2126 440 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 4.8E-16 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 GBCGDNIH2_RS06885 16d7e88b989addcbf95474564cee2126 440 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 4.8E-16 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 GBCGDNIH2_RS06885 16d7e88b989addcbf95474564cee2126 440 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 4.8E-16 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 GBCGDNIH2_RS06885 16d7e88b989addcbf95474564cee2126 440 SUPERFAMILY SSF55681 9 238 3.32E-93 T 29-03-2018 GBCGDNIH2_RS06885 16d7e88b989addcbf95474564cee2126 440 SUPERFAMILY SSF55681 280 351 3.32E-93 T 29-03-2018 GBCGDNIH2_RS10920 69330675836c249a0b210e5ead6baf70 889 Gene3D G3DSA:3.50.30.10 402 544 7.5E-43 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 GBCGDNIH2_RS10920 69330675836c249a0b210e5ead6baf70 889 SUPERFAMILY SSF56059 1 390 1.65E-147 T 29-03-2018 GBCGDNIH2_RS10920 69330675836c249a0b210e5ead6baf70 889 TIGRFAM TIGR01828 pyru_phos_dikin: pyruvate, phosphate dikinase 3 881 0.0 T 29-03-2018 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 GBCGDNIH2_RS10920 69330675836c249a0b210e5ead6baf70 889 Gene3D G3DSA:3.20.20.60 545 883 1.3E-114 T 29-03-2018 GBCGDNIH2_RS10920 69330675836c249a0b210e5ead6baf70 889 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 312 368 1.1E-11 T 29-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 GBCGDNIH2_RS10920 69330675836c249a0b210e5ead6baf70 889 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 21 294 6.7E-51 T 29-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 GBCGDNIH2_RS10920 69330675836c249a0b210e5ead6baf70 889 Gene3D G3DSA:1.20.80.30 121 201 1.8E-34 T 29-03-2018 GBCGDNIH2_RS10920 69330675836c249a0b210e5ead6baf70 889 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 460 471 - T 29-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 GBCGDNIH2_RS10920 69330675836c249a0b210e5ead6baf70 889 Gene3D G3DSA:1.10.189.10 354 401 6.3E-21 T 29-03-2018 GBCGDNIH2_RS10920 69330675836c249a0b210e5ead6baf70 889 Gene3D G3DSA:3.30.1490.20 2 120 1.0E-33 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 GBCGDNIH2_RS10920 69330675836c249a0b210e5ead6baf70 889 Gene3D G3DSA:3.30.470.20 247 353 1.2E-25 T 29-03-2018 GBCGDNIH2_RS10920 69330675836c249a0b210e5ead6baf70 889 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 771 789 - T 29-03-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 GBCGDNIH2_RS10920 69330675836c249a0b210e5ead6baf70 889 SUPERFAMILY SSF52009 399 522 4.45E-38 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 GBCGDNIH2_RS10920 69330675836c249a0b210e5ead6baf70 889 SUPERFAMILY SSF51621 521 881 2.17E-127 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 GBCGDNIH2_RS10920 69330675836c249a0b210e5ead6baf70 889 PIRSF PIRSF000853 1 888 0.0 T 29-03-2018 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 GBCGDNIH2_RS10920 69330675836c249a0b210e5ead6baf70 889 Pfam PF00391 PEP-utilising enzyme, mobile domain 432 513 6.1E-27 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 GBCGDNIH2_RS10920 69330675836c249a0b210e5ead6baf70 889 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 528 879 2.1E-89 T 29-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 GBCGDNIH2_RS08565 8704e4abbf7bb32fcfa4623ec6354924 305 TIGRFAM TIGR03707 PPK2_P_aer: polyphosphate kinase 2 51 276 4.1E-111 T 29-03-2018 IPR022486 Polyphosphate kinase 2, PA0141 GO:0006793|GO:0008976 GBCGDNIH2_RS08565 8704e4abbf7bb32fcfa4623ec6354924 305 Gene3D G3DSA:3.40.50.300 8 296 6.1E-107 T 29-03-2018 GBCGDNIH2_RS08565 8704e4abbf7bb32fcfa4623ec6354924 305 PIRSF PIRSF028756 16 305 1.3E-130 T 29-03-2018 IPR016898 Polyphosphate kinase 2 GBCGDNIH2_RS08565 8704e4abbf7bb32fcfa4623ec6354924 305 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 51 275 3.8E-110 T 29-03-2018 IPR022488 Polyphosphate kinase-2-related GBCGDNIH2_RS08565 8704e4abbf7bb32fcfa4623ec6354924 305 SUPERFAMILY SSF52540 81 268 1.49E-27 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS08795 6ed1d911db7ef2696f7f81ab54fd81f1 724 SUPERFAMILY SSF55326 391 556 6.15E-52 T 29-03-2018 IPR016188 PurM-like, N-terminal domain GBCGDNIH2_RS08795 6ed1d911db7ef2696f7f81ab54fd81f1 724 SUPERFAMILY SSF56042 564 721 2.99E-30 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain GBCGDNIH2_RS08795 6ed1d911db7ef2696f7f81ab54fd81f1 724 Pfam PF02769 AIR synthase related protein, C-terminal domain 569 694 2.8E-17 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain GBCGDNIH2_RS08795 6ed1d911db7ef2696f7f81ab54fd81f1 724 Pfam PF02769 AIR synthase related protein, C-terminal domain 199 351 4.0E-36 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain GBCGDNIH2_RS08795 6ed1d911db7ef2696f7f81ab54fd81f1 724 PIRSF PIRSF001587 2 724 3.1E-283 T 29-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 GBCGDNIH2_RS08795 6ed1d911db7ef2696f7f81ab54fd81f1 724 SUPERFAMILY SSF56042 196 418 7.18E-57 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain GBCGDNIH2_RS08795 6ed1d911db7ef2696f7f81ab54fd81f1 724 Gene3D G3DSA:3.90.650.10 176 369 1.3E-39 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain GBCGDNIH2_RS08795 6ed1d911db7ef2696f7f81ab54fd81f1 724 Gene3D G3DSA:3.30.1330.10 41 175 2.5E-49 T 29-03-2018 IPR016188 PurM-like, N-terminal domain GBCGDNIH2_RS08795 6ed1d911db7ef2696f7f81ab54fd81f1 724 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 724 316.949 T 29-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 GBCGDNIH2_RS08795 6ed1d911db7ef2696f7f81ab54fd81f1 724 SUPERFAMILY SSF55326 11 193 2.39E-52 T 29-03-2018 IPR016188 PurM-like, N-terminal domain GBCGDNIH2_RS08795 6ed1d911db7ef2696f7f81ab54fd81f1 724 Pfam PF00586 AIR synthase related protein, N-terminal domain 84 186 2.5E-23 T 29-03-2018 IPR016188 PurM-like, N-terminal domain GBCGDNIH2_RS08795 6ed1d911db7ef2696f7f81ab54fd81f1 724 Pfam PF00586 AIR synthase related protein, N-terminal domain 434 550 3.8E-21 T 29-03-2018 IPR016188 PurM-like, N-terminal domain GBCGDNIH2_RS08795 6ed1d911db7ef2696f7f81ab54fd81f1 724 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 15 720 2.9E-278 T 29-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 GBCGDNIH2_RS08795 6ed1d911db7ef2696f7f81ab54fd81f1 724 Gene3D G3DSA:3.90.650.10 560 723 2.7E-30 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain GBCGDNIH2_RS08795 6ed1d911db7ef2696f7f81ab54fd81f1 724 Gene3D G3DSA:3.30.1330.10 380 556 3.3E-43 T 29-03-2018 IPR016188 PurM-like, N-terminal domain GBCGDNIH2_RS09035 e14bc793ad5dd42291ee698e798f9710 299 PRINTS PR00073 Coprogen oxidase signature 114 138 5.8E-44 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 GBCGDNIH2_RS09035 e14bc793ad5dd42291ee698e798f9710 299 PRINTS PR00073 Coprogen oxidase signature 184 213 5.8E-44 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 GBCGDNIH2_RS09035 e14bc793ad5dd42291ee698e798f9710 299 PRINTS PR00073 Coprogen oxidase signature 256 283 5.8E-44 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 GBCGDNIH2_RS09035 e14bc793ad5dd42291ee698e798f9710 299 PRINTS PR00073 Coprogen oxidase signature 284 299 5.8E-44 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 GBCGDNIH2_RS09035 e14bc793ad5dd42291ee698e798f9710 299 PRINTS PR00073 Coprogen oxidase signature 51 67 5.8E-44 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 GBCGDNIH2_RS09035 e14bc793ad5dd42291ee698e798f9710 299 ProSitePatterns PS01021 Coproporphyrinogen III oxidase signature. 188 212 - T 29-03-2018 IPR018375 Coproporphyrinogen III oxidase, conserved site GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 GBCGDNIH2_RS09035 e14bc793ad5dd42291ee698e798f9710 299 Gene3D G3DSA:3.40.1500.10 4 299 1.5E-114 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 GBCGDNIH2_RS09035 e14bc793ad5dd42291ee698e798f9710 299 PIRSF PIRSF000166 2 299 1.7E-111 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 GBCGDNIH2_RS09035 e14bc793ad5dd42291ee698e798f9710 299 Hamap MF_00333 Oxygen-dependent coproporphyrinogen-III oxidase [hemF]. 11 299 51.841 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 GBCGDNIH2_RS09035 e14bc793ad5dd42291ee698e798f9710 299 SUPERFAMILY SSF102886 9 299 4.05E-113 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 GBCGDNIH2_RS09035 e14bc793ad5dd42291ee698e798f9710 299 Pfam PF01218 Coproporphyrinogen III oxidase 20 298 3.4E-93 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 GBCGDNIH2_RS00450 e79f2be72ac76c05172335bb02cf543a 415 Gene3D G3DSA:3.90.1150.10 281 415 1.8E-41 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 GBCGDNIH2_RS00450 e79f2be72ac76c05172335bb02cf543a 415 TIGRFAM TIGR01325 O_suc_HS_sulf: O-succinylhomoserine sulfhydrylase 31 411 9.9E-167 T 29-03-2018 IPR006234 O-succinylhomoserine sulfhydrylase GO:0071268 GBCGDNIH2_RS00450 e79f2be72ac76c05172335bb02cf543a 415 Hamap MF_02056 O-succinylhomoserine sulfhydrylase [metZ]. 32 412 51.368 T 29-03-2018 IPR006234 O-succinylhomoserine sulfhydrylase GO:0071268 GBCGDNIH2_RS00450 e79f2be72ac76c05172335bb02cf543a 415 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 32 411 2.2E-122 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 GBCGDNIH2_RS00450 e79f2be72ac76c05172335bb02cf543a 415 Gene3D G3DSA:3.40.640.10 28 280 1.3E-55 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GBCGDNIH2_RS00450 e79f2be72ac76c05172335bb02cf543a 415 SUPERFAMILY SSF53383 43 412 1.86E-110 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase GBCGDNIH2_RS00450 e79f2be72ac76c05172335bb02cf543a 415 PIRSF PIRSF001434 16 414 6.1E-121 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 GBCGDNIH2_RS00710 b1bf69be76ab5516e98e8180bb40a815 370 Gene3D G3DSA:3.90.1150.10 248 354 2.1E-24 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 GBCGDNIH2_RS00710 b1bf69be76ab5516e98e8180bb40a815 370 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 8 356 7.2E-89 T 29-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 GBCGDNIH2_RS00710 b1bf69be76ab5516e98e8180bb40a815 370 Gene3D G3DSA:3.40.640.10 42 247 1.3E-43 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GBCGDNIH2_RS00710 b1bf69be76ab5516e98e8180bb40a815 370 SUPERFAMILY SSF53383 24 358 1.26E-82 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase GBCGDNIH2_RS00710 b1bf69be76ab5516e98e8180bb40a815 370 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 5 359 55.448 T 29-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 GBCGDNIH2_RS00710 b1bf69be76ab5516e98e8180bb40a815 370 Pfam PF00155 Aminotransferase class I and II 28 355 3.0E-56 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 GBCGDNIH2_RS10600 439f46d847dff8894345ffecd4ddbf79 760 Pfam PF13089 Polyphosphate kinase N-terminal domain 30 134 5.0E-35 T 29-03-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 GBCGDNIH2_RS10600 439f46d847dff8894345ffecd4ddbf79 760 SUPERFAMILY SSF56024 359 540 7.06E-54 T 29-03-2018 GBCGDNIH2_RS10600 439f46d847dff8894345ffecd4ddbf79 760 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 29 730 4.4E-268 T 29-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 GBCGDNIH2_RS10600 439f46d847dff8894345ffecd4ddbf79 760 Gene3D G3DSA:3.30.870.10 367 542 3.8E-19 T 29-03-2018 GBCGDNIH2_RS10600 439f46d847dff8894345ffecd4ddbf79 760 SUPERFAMILY SSF56024 544 729 6.73E-66 T 29-03-2018 GBCGDNIH2_RS10600 439f46d847dff8894345ffecd4ddbf79 760 Gene3D G3DSA:3.30.870.10 543 736 1.8E-35 T 29-03-2018 GBCGDNIH2_RS10600 439f46d847dff8894345ffecd4ddbf79 760 Gene3D G3DSA:1.20.58.310 32 136 2.7E-33 T 29-03-2018 GBCGDNIH2_RS10600 439f46d847dff8894345ffecd4ddbf79 760 SUPERFAMILY SSF143724 152 355 1.84E-49 T 29-03-2018 GBCGDNIH2_RS10600 439f46d847dff8894345ffecd4ddbf79 760 SUPERFAMILY SSF140356 27 125 1.7E-35 T 29-03-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 GBCGDNIH2_RS10600 439f46d847dff8894345ffecd4ddbf79 760 Pfam PF02503 Polyphosphate kinase middle domain 158 363 4.6E-48 T 29-03-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 GBCGDNIH2_RS10600 439f46d847dff8894345ffecd4ddbf79 760 Pfam PF13090 Polyphosphate kinase C-terminal domain 373 728 6.1E-148 T 29-03-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 GBCGDNIH2_RS10600 439f46d847dff8894345ffecd4ddbf79 760 PIRSF PIRSF015589 10 740 1.1E-247 T 29-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 GBCGDNIH2_RS10600 439f46d847dff8894345ffecd4ddbf79 760 Hamap MF_00347 Polyphosphate kinase [ppk]. 28 733 27.549 T 29-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 GBCGDNIH2_RS10600 439f46d847dff8894345ffecd4ddbf79 760 Gene3D G3DSA:3.30.1840.10 146 347 1.5E-44 T 29-03-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 GBCGDNIH2_RS02400 88064589e5d2db20e8d6243bf814c947 313 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 19 305 1.4E-80 T 29-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 GBCGDNIH2_RS02400 88064589e5d2db20e8d6243bf814c947 313 Pfam PF01687 Riboflavin kinase 182 305 4.1E-36 T 29-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 GBCGDNIH2_RS02400 88064589e5d2db20e8d6243bf814c947 313 Pfam PF06574 FAD synthetase 13 165 2.8E-42 T 29-03-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 GBCGDNIH2_RS02400 88064589e5d2db20e8d6243bf814c947 313 Gene3D G3DSA:2.40.30.30 178 312 9.0E-39 T 29-03-2018 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 Reactome: R-HSA-196843 GBCGDNIH2_RS02400 88064589e5d2db20e8d6243bf814c947 313 Gene3D G3DSA:3.40.50.620 1 177 9.3E-42 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GBCGDNIH2_RS02400 88064589e5d2db20e8d6243bf814c947 313 SUPERFAMILY SSF52374 19 175 6.22E-26 T 29-03-2018 GBCGDNIH2_RS02400 88064589e5d2db20e8d6243bf814c947 313 PIRSF PIRSF004491 1 313 4.6E-95 T 29-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 GBCGDNIH2_RS02400 88064589e5d2db20e8d6243bf814c947 313 SUPERFAMILY SSF82114 172 308 1.02E-42 T 29-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 GBCGDNIH2_RS02400 88064589e5d2db20e8d6243bf814c947 313 SMART SM00904 181 306 2.6E-59 T 29-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 GBCGDNIH2_RS10495 6f0153129141e37d4c9e631e4655eaae 430 Gene3D G3DSA:3.40.1190.10 5 287 2.9E-76 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 GBCGDNIH2_RS10495 6f0153129141e37d4c9e631e4655eaae 430 Gene3D G3DSA:3.90.190.20 288 428 2.2E-18 T 29-03-2018 GBCGDNIH2_RS10495 6f0153129141e37d4c9e631e4655eaae 430 ProSitePatterns PS01012 Folylpolyglutamate synthase signature 2. 138 153 - T 29-03-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 GBCGDNIH2_RS10495 6f0153129141e37d4c9e631e4655eaae 430 PIRSF PIRSF001563 1 429 2.7E-105 T 29-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 GBCGDNIH2_RS10495 6f0153129141e37d4c9e631e4655eaae 430 SUPERFAMILY SSF53623 7 286 5.04E-84 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 GBCGDNIH2_RS10495 6f0153129141e37d4c9e631e4655eaae 430 Pfam PF08245 Mur ligase middle domain 48 263 2.7E-7 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 GBCGDNIH2_RS10495 6f0153129141e37d4c9e631e4655eaae 430 SUPERFAMILY SSF53244 286 425 5.04E-20 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 GBCGDNIH2_RS10495 6f0153129141e37d4c9e631e4655eaae 430 TIGRFAM TIGR01499 folC: bifunctional protein FolC 25 425 7.1E-105 T 29-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 GBCGDNIH2_RS00290 307956844d313af9acd65fa83a11a7c8 412 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 10 386 3.7E-77 T 29-03-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 GBCGDNIH2_RS00290 307956844d313af9acd65fa83a11a7c8 412 Gene3D G3DSA:1.20.1250.20 204 388 1.3E-8 T 29-03-2018 GBCGDNIH2_RS00290 307956844d313af9acd65fa83a11a7c8 412 Gene3D G3DSA:1.20.1250.20 3 195 8.0E-28 T 29-03-2018 GBCGDNIH2_RS00290 307956844d313af9acd65fa83a11a7c8 412 Pfam PF07690 Major Facilitator Superfamily 16 359 7.5E-30 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 GBCGDNIH2_RS00290 307956844d313af9acd65fa83a11a7c8 412 SUPERFAMILY SSF103473 5 385 1.83E-50 T 29-03-2018 IPR020846 Major facilitator superfamily domain GBCGDNIH2_RS04440 8924aced960796850816ac976f000b5a 311 SUPERFAMILY SSF56281 36 274 6.91E-41 T 29-03-2018 IPR001279 Metallo-beta-lactamase GBCGDNIH2_RS04440 8924aced960796850816ac976f000b5a 311 Gene3D G3DSA:3.60.15.10 26 311 2.0E-46 T 29-03-2018 IPR001279 Metallo-beta-lactamase GBCGDNIH2_RS04440 8924aced960796850816ac976f000b5a 311 Pfam PF00753 Metallo-beta-lactamase superfamily 50 228 5.6E-16 T 29-03-2018 IPR001279 Metallo-beta-lactamase GBCGDNIH2_RS04440 8924aced960796850816ac976f000b5a 311 SMART SM00849 38 228 2.3E-15 T 29-03-2018 IPR001279 Metallo-beta-lactamase GBCGDNIH2_RS10370 8e227850d29d6355e462616b5362b6de 309 Gene3D G3DSA:3.40.50.2000 132 301 4.6E-36 T 29-03-2018 GBCGDNIH2_RS10370 8e227850d29d6355e462616b5362b6de 309 Gene3D G3DSA:3.40.50.2000 1 114 1.2E-18 T 29-03-2018 GBCGDNIH2_RS10370 8e227850d29d6355e462616b5362b6de 309 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 133 271 1.3E-26 T 29-03-2018 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 GBCGDNIH2_RS10370 8e227850d29d6355e462616b5362b6de 309 SUPERFAMILY SSF53756 1 298 2.93E-64 T 29-03-2018 GBCGDNIH2_RS05615 44d5b116b4bf237ca95263177e98fc2d 184 SUPERFAMILY SSF51283 3 183 1.15E-50 T 29-03-2018 IPR029054 dUTPase-like GBCGDNIH2_RS05615 44d5b116b4bf237ca95263177e98fc2d 184 Gene3D G3DSA:2.70.40.10 1 157 4.0E-56 T 29-03-2018 GBCGDNIH2_RS05615 44d5b116b4bf237ca95263177e98fc2d 184 Hamap MF_00146 dCTP deaminase [dcd]. 1 184 28.932 T 29-03-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 GBCGDNIH2_RS05615 44d5b116b4bf237ca95263177e98fc2d 184 Pfam PF00692 dUTPase 78 178 1.6E-6 T 29-03-2018 IPR029054 dUTPase-like GBCGDNIH2_RS05615 44d5b116b4bf237ca95263177e98fc2d 184 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 6 184 1.2E-48 T 29-03-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 GBCGDNIH2_RS06215 212af6962c8a66fc5e1ee8bba68b0f63 94 Pfam PF05930 Prophage CP4-57 regulatory protein (AlpA) 10 60 3.6E-18 T 29-03-2018 IPR010260 DNA-binding transcriptional activator AlpA GBCGDNIH2_RS06215 212af6962c8a66fc5e1ee8bba68b0f63 94 SUPERFAMILY SSF46955 12 66 2.93E-5 T 29-03-2018 IPR009061 Putative DNA-binding domain GBCGDNIH2_RS06215 212af6962c8a66fc5e1ee8bba68b0f63 94 Gene3D G3DSA:1.10.10.10 12 73 1.8E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS12425 229999980d65d08c474b9b8b62294328 289 Pfam PF03631 Virulence factor BrkB 18 273 3.0E-55 T 29-03-2018 IPR017039 Virulence factor BrkB GBCGDNIH2_RS12425 229999980d65d08c474b9b8b62294328 289 PIRSF PIRSF035875 1 287 5.5E-69 T 29-03-2018 IPR017039 Virulence factor BrkB GBCGDNIH2_RS12425 229999980d65d08c474b9b8b62294328 289 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 15 268 3.6E-27 T 29-03-2018 IPR017039 Virulence factor BrkB GBCGDNIH2_RS05290 8b80364ad3d6ef3194fc0243c7b62359 581 SUPERFAMILY SSF56235 36 580 1.21E-153 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal GBCGDNIH2_RS05290 8b80364ad3d6ef3194fc0243c7b62359 581 Pfam PF01019 Gamma-glutamyltranspeptidase 58 576 3.9E-145 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 GBCGDNIH2_RS05290 8b80364ad3d6ef3194fc0243c7b62359 581 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 400 418 1.1E-60 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 GBCGDNIH2_RS05290 8b80364ad3d6ef3194fc0243c7b62359 581 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 140 158 1.1E-60 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 GBCGDNIH2_RS05290 8b80364ad3d6ef3194fc0243c7b62359 581 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 65 90 1.1E-60 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 GBCGDNIH2_RS05290 8b80364ad3d6ef3194fc0243c7b62359 581 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 158 177 1.1E-60 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 GBCGDNIH2_RS05290 8b80364ad3d6ef3194fc0243c7b62359 581 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 258 274 1.1E-60 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 GBCGDNIH2_RS05290 8b80364ad3d6ef3194fc0243c7b62359 581 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 458 473 1.1E-60 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 GBCGDNIH2_RS05290 8b80364ad3d6ef3194fc0243c7b62359 581 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 288 307 1.1E-60 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 GBCGDNIH2_RS05290 8b80364ad3d6ef3194fc0243c7b62359 581 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 422 440 1.1E-60 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 GBCGDNIH2_RS05290 8b80364ad3d6ef3194fc0243c7b62359 581 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 483 500 1.1E-60 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 GBCGDNIH2_RS05290 8b80364ad3d6ef3194fc0243c7b62359 581 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 44 573 1.4E-119 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 GBCGDNIH2_RS00120 a1a9b15839cfd5afa41ab06ad73e469e 362 Gene3D G3DSA:1.10.10.10 14 101 2.4E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS00120 a1a9b15839cfd5afa41ab06ad73e469e 362 Pfam PF01628 HrcA protein C terminal domain 120 342 3.3E-52 T 29-03-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 GBCGDNIH2_RS00120 a1a9b15839cfd5afa41ab06ad73e469e 362 Gene3D G3DSA:3.30.450.40 199 361 7.2E-36 T 29-03-2018 IPR029016 GAF domain-like GBCGDNIH2_RS00120 a1a9b15839cfd5afa41ab06ad73e469e 362 SUPERFAMILY SSF55781 88 357 1.77E-52 T 29-03-2018 IPR029016 GAF domain-like GBCGDNIH2_RS00120 a1a9b15839cfd5afa41ab06ad73e469e 362 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 17 349 27.655 T 29-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 GBCGDNIH2_RS00120 a1a9b15839cfd5afa41ab06ad73e469e 362 SUPERFAMILY SSF46785 18 100 3.14E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS00120 a1a9b15839cfd5afa41ab06ad73e469e 362 PIRSF PIRSF005485 15 359 7.3E-108 T 29-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 GBCGDNIH2_RS00120 a1a9b15839cfd5afa41ab06ad73e469e 362 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 19 355 3.6E-89 T 29-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 GBCGDNIH2_RS09615 d3205f72265fbd9257b4667f9d64113a 1168 Pfam PF00072 Response regulator receiver domain 946 1058 2.4E-14 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GBCGDNIH2_RS09615 d3205f72265fbd9257b4667f9d64113a 1168 SUPERFAMILY SSF47384 679 759 2.55E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GBCGDNIH2_RS09615 d3205f72265fbd9257b4667f9d64113a 1168 PRINTS PR00344 Bacterial sensor protein C-terminal signature 859 869 2.9E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS09615 d3205f72265fbd9257b4667f9d64113a 1168 PRINTS PR00344 Bacterial sensor protein C-terminal signature 900 913 2.9E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS09615 d3205f72265fbd9257b4667f9d64113a 1168 PRINTS PR00344 Bacterial sensor protein C-terminal signature 876 894 2.9E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS09615 d3205f72265fbd9257b4667f9d64113a 1168 PRINTS PR00344 Bacterial sensor protein C-terminal signature 841 855 2.9E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS09615 d3205f72265fbd9257b4667f9d64113a 1168 SMART SM00388 692 758 1.9E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GBCGDNIH2_RS09615 d3205f72265fbd9257b4667f9d64113a 1168 SUPERFAMILY SSF55874 748 912 2.1E-45 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS09615 d3205f72265fbd9257b4667f9d64113a 1168 Gene3D G3DSA:1.10.287.130 682 754 3.1E-16 T 29-03-2018 GBCGDNIH2_RS09615 d3205f72265fbd9257b4667f9d64113a 1168 Gene3D G3DSA:3.30.565.10 762 925 7.4E-46 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS09615 d3205f72265fbd9257b4667f9d64113a 1168 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 805 914 2.3E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS09615 d3205f72265fbd9257b4667f9d64113a 1168 Gene3D G3DSA:3.40.50.2300 934 1107 5.9E-22 T 29-03-2018 GBCGDNIH2_RS09615 d3205f72265fbd9257b4667f9d64113a 1168 SMART SM00448 943 1060 6.1E-14 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GBCGDNIH2_RS09615 d3205f72265fbd9257b4667f9d64113a 1168 SMART SM00387 805 916 3.2E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS09615 d3205f72265fbd9257b4667f9d64113a 1168 SUPERFAMILY SSF52172 941 1066 1.57E-23 T 29-03-2018 IPR011006 CheY-like superfamily GBCGDNIH2_RS09615 d3205f72265fbd9257b4667f9d64113a 1168 Pfam PF00512 His Kinase A (phospho-acceptor) domain 692 758 8.0E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GBCGDNIH2_RS00185 c9e8d827feed829cecd9429b615975b2 484 SUPERFAMILY SSF56801 39 477 1.37E-42 T 29-03-2018 GBCGDNIH2_RS00185 c9e8d827feed829cecd9429b615975b2 484 Pfam PF00501 AMP-binding enzyme 139 310 1.3E-16 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 GBCGDNIH2_RS00185 c9e8d827feed829cecd9429b615975b2 484 Gene3D G3DSA:3.40.50.980 6 160 1.8E-6 T 29-03-2018 GBCGDNIH2_RS00185 c9e8d827feed829cecd9429b615975b2 484 Gene3D G3DSA:3.30.300.30 375 482 7.0E-12 T 29-03-2018 GBCGDNIH2_RS00185 c9e8d827feed829cecd9429b615975b2 484 Gene3D G3DSA:3.40.50.980 161 320 2.1E-24 T 29-03-2018 GBCGDNIH2_RS06510 41bd70434872ac7aa8f6078cb0c68d12 284 Pfam PF00950 ABC 3 transport family 15 272 1.8E-50 T 29-03-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 GBCGDNIH2_RS06510 41bd70434872ac7aa8f6078cb0c68d12 284 Gene3D G3DSA:1.10.3470.10 6 278 1.2E-12 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like GBCGDNIH2_RS06510 41bd70434872ac7aa8f6078cb0c68d12 284 SUPERFAMILY SSF81345 10 270 9.15E-19 T 29-03-2018 IPR029022 ABC transporter, BtuC-like GBCGDNIH2_RS02695 7bfaa7e9f5225fff223f3e9dc10d73f0 182 TIGRFAM TIGR03126 one_C_fae: formaldehyde-activating enzyme 8 171 4.3E-35 T 29-03-2018 IPR014826 Formaldehyde-activating enzyme GO:0016051|GO:0016840 KEGG: 00030+4.1.2.43|KEGG: 00680+4.2.1.147+4.1.2.43|MetaCyc: PWY-1723|MetaCyc: PWY-1861|MetaCyc: PWY-7796 GBCGDNIH2_RS02695 7bfaa7e9f5225fff223f3e9dc10d73f0 182 Gene3D G3DSA:3.30.230.60 7 174 1.5E-54 T 29-03-2018 IPR014826 Formaldehyde-activating enzyme GO:0016051|GO:0016840 KEGG: 00030+4.1.2.43|KEGG: 00680+4.2.1.147+4.1.2.43|MetaCyc: PWY-1723|MetaCyc: PWY-1861|MetaCyc: PWY-7796 GBCGDNIH2_RS02695 7bfaa7e9f5225fff223f3e9dc10d73f0 182 SUPERFAMILY SSF54211 3 175 7.21E-52 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold GBCGDNIH2_RS02695 7bfaa7e9f5225fff223f3e9dc10d73f0 182 Pfam PF08714 Formaldehyde-activating enzyme (Fae) 9 173 6.4E-57 T 29-03-2018 IPR014826 Formaldehyde-activating enzyme GO:0016051|GO:0016840 KEGG: 00030+4.1.2.43|KEGG: 00680+4.2.1.147+4.1.2.43|MetaCyc: PWY-1723|MetaCyc: PWY-1861|MetaCyc: PWY-7796 GBCGDNIH2_RS10940 74ed5f1ced54ab0fab6fb77bb1b51e47 285 Gene3D G3DSA:1.20.58.180 211 284 4.2E-36 T 29-03-2018 GBCGDNIH2_RS10940 74ed5f1ced54ab0fab6fb77bb1b51e47 285 SUPERFAMILY SSF55681 6 281 2.49E-128 T 29-03-2018 GBCGDNIH2_RS10940 74ed5f1ced54ab0fab6fb77bb1b51e47 285 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 5 282 54.982 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 GBCGDNIH2_RS10940 74ed5f1ced54ab0fab6fb77bb1b51e47 285 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 160 175 2.4E-59 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 GBCGDNIH2_RS10940 74ed5f1ced54ab0fab6fb77bb1b51e47 285 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 59 74 2.4E-59 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 GBCGDNIH2_RS10940 74ed5f1ced54ab0fab6fb77bb1b51e47 285 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 137 157 2.4E-59 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 GBCGDNIH2_RS10940 74ed5f1ced54ab0fab6fb77bb1b51e47 285 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 80 100 2.4E-59 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 GBCGDNIH2_RS10940 74ed5f1ced54ab0fab6fb77bb1b51e47 285 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 246 262 2.4E-59 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 GBCGDNIH2_RS10940 74ed5f1ced54ab0fab6fb77bb1b51e47 285 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 111 135 2.4E-59 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 GBCGDNIH2_RS10940 74ed5f1ced54ab0fab6fb77bb1b51e47 285 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 6 281 3.4E-134 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 GBCGDNIH2_RS10940 74ed5f1ced54ab0fab6fb77bb1b51e47 285 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 7 282 4.4E-143 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 GBCGDNIH2_RS10940 74ed5f1ced54ab0fab6fb77bb1b51e47 285 Gene3D G3DSA:3.30.930.10 1 209 3.7E-82 T 29-03-2018 GBCGDNIH2_RS10760 356db6f277663088dda66dcdf842944f 463 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 344 453 2.2E-39 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 GBCGDNIH2_RS10760 356db6f277663088dda66dcdf842944f 463 SUPERFAMILY SSF55424 340 462 1.12E-43 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 GBCGDNIH2_RS10760 356db6f277663088dda66dcdf842944f 463 Gene3D G3DSA:3.30.390.30 332 460 2.4E-45 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 GBCGDNIH2_RS10760 356db6f277663088dda66dcdf842944f 463 PIRSF PIRSF000350 1 460 2.3E-85 T 29-03-2018 GBCGDNIH2_RS10760 356db6f277663088dda66dcdf842944f 463 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 40 50 - T 29-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 GBCGDNIH2_RS10760 356db6f277663088dda66dcdf842944f 463 Gene3D G3DSA:3.40.50.720 162 331 4.6E-38 T 29-03-2018 GBCGDNIH2_RS10760 356db6f277663088dda66dcdf842944f 463 Gene3D G3DSA:3.50.50.60 1 161 4.9E-32 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS10760 356db6f277663088dda66dcdf842944f 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.7E-38 T 29-03-2018 GBCGDNIH2_RS10760 356db6f277663088dda66dcdf842944f 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 290 312 1.7E-38 T 29-03-2018 GBCGDNIH2_RS10760 356db6f277663088dda66dcdf842944f 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 172 190 1.7E-38 T 29-03-2018 GBCGDNIH2_RS10760 356db6f277663088dda66dcdf842944f 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 277 1.7E-38 T 29-03-2018 GBCGDNIH2_RS10760 356db6f277663088dda66dcdf842944f 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 133 151 1.7E-38 T 29-03-2018 GBCGDNIH2_RS10760 356db6f277663088dda66dcdf842944f 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 1.9E-77 T 29-03-2018 GBCGDNIH2_RS10760 356db6f277663088dda66dcdf842944f 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 262 276 1.9E-77 T 29-03-2018 GBCGDNIH2_RS10760 356db6f277663088dda66dcdf842944f 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 305 312 1.9E-77 T 29-03-2018 GBCGDNIH2_RS10760 356db6f277663088dda66dcdf842944f 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 340 361 1.9E-77 T 29-03-2018 GBCGDNIH2_RS10760 356db6f277663088dda66dcdf842944f 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 1.9E-77 T 29-03-2018 GBCGDNIH2_RS10760 356db6f277663088dda66dcdf842944f 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 427 447 1.9E-77 T 29-03-2018 GBCGDNIH2_RS10760 356db6f277663088dda66dcdf842944f 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 405 420 1.9E-77 T 29-03-2018 GBCGDNIH2_RS10760 356db6f277663088dda66dcdf842944f 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 172 197 1.9E-77 T 29-03-2018 GBCGDNIH2_RS10760 356db6f277663088dda66dcdf842944f 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 136 145 1.9E-77 T 29-03-2018 GBCGDNIH2_RS10760 356db6f277663088dda66dcdf842944f 463 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 325 7.5E-73 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS10760 356db6f277663088dda66dcdf842944f 463 SUPERFAMILY SSF51905 2 363 2.09E-67 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS10760 356db6f277663088dda66dcdf842944f 463 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 5 463 5.3E-174 T 29-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 GBCGDNIH2_RS04115 c3b03b22d9b1683c57217b03c65c6ee0 230 SUPERFAMILY SSF53335 51 170 1.89E-18 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GBCGDNIH2_RS04115 c3b03b22d9b1683c57217b03c65c6ee0 230 Gene3D G3DSA:3.40.50.150 49 225 2.6E-16 T 29-03-2018 GBCGDNIH2_RS04115 c3b03b22d9b1683c57217b03c65c6ee0 230 Pfam PF13649 Methyltransferase domain 88 180 7.1E-7 T 29-03-2018 GBCGDNIH2_RS08465 84bbeecb18698952a16609a240df9e7e 737 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 37 72 5.8E-5 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08465 84bbeecb18698952a16609a240df9e7e 737 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 93 128 7.0E-6 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08465 84bbeecb18698952a16609a240df9e7e 737 SUPERFAMILY SSF51120 350 485 9.29E-12 T 29-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal GBCGDNIH2_RS08465 84bbeecb18698952a16609a240df9e7e 737 Gene3D G3DSA:2.150.10.10 538 730 2.1E-10 T 29-03-2018 GBCGDNIH2_RS08465 84bbeecb18698952a16609a240df9e7e 737 Gene3D G3DSA:2.150.10.10 449 537 0.059 T 29-03-2018 GBCGDNIH2_RS08465 84bbeecb18698952a16609a240df9e7e 737 Gene3D G3DSA:2.150.10.10 203 448 5.5E-9 T 29-03-2018 GBCGDNIH2_RS08465 84bbeecb18698952a16609a240df9e7e 737 SUPERFAMILY SSF51120 499 636 2.72E-9 T 29-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal GBCGDNIH2_RS08465 84bbeecb18698952a16609a240df9e7e 737 SUPERFAMILY SSF51120 668 704 2.72E-9 T 29-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal GBCGDNIH2_RS01705 0a6bf165da856e06ac3b4ce64e963a58 281 SUPERFAMILY SSF56317 1 278 1.44E-75 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 GBCGDNIH2_RS01705 0a6bf165da856e06ac3b4ce64e963a58 281 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 160 180 - T 29-03-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site GBCGDNIH2_RS01705 0a6bf165da856e06ac3b4ce64e963a58 281 Pfam PF00795 Carbon-nitrogen hydrolase 2 269 5.2E-51 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 GBCGDNIH2_RS01705 0a6bf165da856e06ac3b4ce64e963a58 281 Gene3D G3DSA:3.60.110.10 1 280 5.8E-69 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 GBCGDNIH2_RS06400 75cba9b633c7c71188319497a3ec579b 465 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 346 454 1.3E-36 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 GBCGDNIH2_RS06400 75cba9b633c7c71188319497a3ec579b 465 Gene3D G3DSA:3.50.50.60 4 164 1.0E-28 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS06400 75cba9b633c7c71188319497a3ec579b 465 SUPERFAMILY SSF51905 3 335 2.7E-60 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS06400 75cba9b633c7c71188319497a3ec579b 465 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 40 50 - T 29-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 GBCGDNIH2_RS06400 75cba9b633c7c71188319497a3ec579b 465 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 326 1.2E-59 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS06400 75cba9b633c7c71188319497a3ec579b 465 Gene3D G3DSA:3.30.390.30 357 465 3.9E-40 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 GBCGDNIH2_RS06400 75cba9b633c7c71188319497a3ec579b 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 8.0E-68 T 29-03-2018 GBCGDNIH2_RS06400 75cba9b633c7c71188319497a3ec579b 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 264 278 8.0E-68 T 29-03-2018 GBCGDNIH2_RS06400 75cba9b633c7c71188319497a3ec579b 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 140 149 8.0E-68 T 29-03-2018 GBCGDNIH2_RS06400 75cba9b633c7c71188319497a3ec579b 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 8.0E-68 T 29-03-2018 GBCGDNIH2_RS06400 75cba9b633c7c71188319497a3ec579b 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 176 201 8.0E-68 T 29-03-2018 GBCGDNIH2_RS06400 75cba9b633c7c71188319497a3ec579b 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 429 449 8.0E-68 T 29-03-2018 GBCGDNIH2_RS06400 75cba9b633c7c71188319497a3ec579b 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 306 313 8.0E-68 T 29-03-2018 GBCGDNIH2_RS06400 75cba9b633c7c71188319497a3ec579b 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 342 363 8.0E-68 T 29-03-2018 GBCGDNIH2_RS06400 75cba9b633c7c71188319497a3ec579b 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 407 422 8.0E-68 T 29-03-2018 GBCGDNIH2_RS06400 75cba9b633c7c71188319497a3ec579b 465 SUPERFAMILY SSF55424 342 464 1.19E-40 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 GBCGDNIH2_RS06400 75cba9b633c7c71188319497a3ec579b 465 PIRSF PIRSF000350 2 460 1.5E-82 T 29-03-2018 GBCGDNIH2_RS06400 75cba9b633c7c71188319497a3ec579b 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 1.8E-34 T 29-03-2018 GBCGDNIH2_RS06400 75cba9b633c7c71188319497a3ec579b 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 176 194 1.8E-34 T 29-03-2018 GBCGDNIH2_RS06400 75cba9b633c7c71188319497a3ec579b 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 263 279 1.8E-34 T 29-03-2018 GBCGDNIH2_RS06400 75cba9b633c7c71188319497a3ec579b 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 291 313 1.8E-34 T 29-03-2018 GBCGDNIH2_RS06400 75cba9b633c7c71188319497a3ec579b 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 137 155 1.8E-34 T 29-03-2018 GBCGDNIH2_RS06400 75cba9b633c7c71188319497a3ec579b 465 Gene3D G3DSA:3.50.50.60 176 356 2.0E-30 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS06400 75cba9b633c7c71188319497a3ec579b 465 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 6 465 3.9E-166 T 29-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 GBCGDNIH2_RS09090 81ba138e37e41a70aa204564f0f6f30a 190 Pfam PF09923 Uncharacterized protein conserved in bacteria (DUF2155) 102 189 5.3E-21 T 29-03-2018 IPR019225 Protein of unknown function DUF2155 GBCGDNIH2_RS11540 4bcb39e12fa6f331a7e282a7807ce9df 644 SUPERFAMILY SSF82771 43 126 2.75E-18 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily GBCGDNIH2_RS11540 4bcb39e12fa6f331a7e282a7807ce9df 644 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 36 615 1.1E-158 T 29-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 GBCGDNIH2_RS11540 4bcb39e12fa6f331a7e282a7807ce9df 644 Hamap MF_00203 UvrABC system protein C [uvrC]. 30 636 26.704 T 29-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 GBCGDNIH2_RS11540 4bcb39e12fa6f331a7e282a7807ce9df 644 SUPERFAMILY SSF47781 550 638 1.68E-20 T 29-03-2018 IPR010994 RuvA domain 2-like GBCGDNIH2_RS11540 4bcb39e12fa6f331a7e282a7807ce9df 644 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 409 571 9.8E-50 T 29-03-2018 IPR001162 UvrC family homology region GBCGDNIH2_RS11540 4bcb39e12fa6f331a7e282a7807ce9df 644 Gene3D G3DSA:4.10.860.10 209 267 4.4E-15 T 29-03-2018 IPR001943 UVR domain GO:0005515 GBCGDNIH2_RS11540 4bcb39e12fa6f331a7e282a7807ce9df 644 Pfam PF01541 GIY-YIG catalytic domain 45 118 5.1E-6 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily GBCGDNIH2_RS11540 4bcb39e12fa6f331a7e282a7807ce9df 644 SMART SM00278 585 604 1.8 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 GBCGDNIH2_RS11540 4bcb39e12fa6f331a7e282a7807ce9df 644 SMART SM00278 617 636 6.6 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 GBCGDNIH2_RS11540 4bcb39e12fa6f331a7e282a7807ce9df 644 SMART SM00465 43 124 3.8E-15 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily GBCGDNIH2_RS11540 4bcb39e12fa6f331a7e282a7807ce9df 644 Pfam PF02151 UvrB/uvrC motif 233 263 3.8E-9 T 29-03-2018 IPR001943 UVR domain GO:0005515 GBCGDNIH2_RS11540 4bcb39e12fa6f331a7e282a7807ce9df 644 Pfam PF14520 Helix-hairpin-helix domain 586 634 1.4E-7 T 29-03-2018 GBCGDNIH2_RS11540 4bcb39e12fa6f331a7e282a7807ce9df 644 Gene3D G3DSA:3.40.1440.10 31 127 1.2E-20 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily GBCGDNIH2_RS11540 4bcb39e12fa6f331a7e282a7807ce9df 644 Gene3D G3DSA:1.10.150.20 583 642 2.4E-13 T 29-03-2018 GBCGDNIH2_RS11540 4bcb39e12fa6f331a7e282a7807ce9df 644 SUPERFAMILY SSF46600 217 267 1.31E-12 T 29-03-2018 IPR001943 UVR domain GO:0005515 GBCGDNIH2_RS00595 8554a5ca7099b1994db1d31483938afc 395 SUPERFAMILY SSF52540 131 331 2.43E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS00595 8554a5ca7099b1994db1d31483938afc 395 Pfam PF02562 PhoH-like protein 156 359 1.1E-89 T 29-03-2018 IPR003714 PhoH-like protein GO:0005524 GBCGDNIH2_RS00595 8554a5ca7099b1994db1d31483938afc 395 Gene3D G3DSA:3.40.50.300 153 359 2.6E-28 T 29-03-2018 GBCGDNIH2_RS03395 9add21068e05d931dd0427add69866c6 381 PIRSF PIRSF026782 17 381 1.7E-119 T 29-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 GBCGDNIH2_RS03395 9add21068e05d931dd0427add69866c6 381 Gene3D G3DSA:3.30.2110.10 23 201 3.1E-59 T 29-03-2018 GBCGDNIH2_RS03395 9add21068e05d931dd0427add69866c6 381 SUPERFAMILY SSF111342 12 302 6.54E-80 T 29-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 GBCGDNIH2_RS03395 9add21068e05d931dd0427add69866c6 381 Hamap MF_00787 Cobalt-precorrin-5B C(1)-methyltransferase [cbiD]. 21 377 27.521 T 29-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 GBCGDNIH2_RS03395 9add21068e05d931dd0427add69866c6 381 Pfam PF01888 CbiD 21 286 3.2E-85 T 29-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 GBCGDNIH2_RS11300 4916a9baa6fc64f7b995636ebb534144 162 Gene3D G3DSA:1.10.3680.10 17 157 2.4E-15 T 29-03-2018 IPR029024 TerB-like GBCGDNIH2_RS11300 4916a9baa6fc64f7b995636ebb534144 162 SUPERFAMILY SSF158682 24 156 1.44E-12 T 29-03-2018 GBCGDNIH2_RS11300 4916a9baa6fc64f7b995636ebb534144 162 Pfam PF05099 Tellurite resistance protein TerB 28 145 7.0E-7 T 29-03-2018 IPR007791 Co-chaperone DjlA, N-terminal GBCGDNIH2_RS00785 bb46de5b687e4eecc3118ccdbb652a5c 574 SUPERFAMILY SSF161098 63 257 1.3E-20 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GBCGDNIH2_RS00785 bb46de5b687e4eecc3118ccdbb652a5c 574 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 389 556 4.6E-10 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GBCGDNIH2_RS00785 bb46de5b687e4eecc3118ccdbb652a5c 574 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 253 7.9E-12 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GBCGDNIH2_RS00785 bb46de5b687e4eecc3118ccdbb652a5c 574 Gene3D G3DSA:1.10.3720.10 359 562 4.1E-18 T 29-03-2018 GBCGDNIH2_RS00785 bb46de5b687e4eecc3118ccdbb652a5c 574 Gene3D G3DSA:1.10.3720.10 17 268 1.1E-18 T 29-03-2018 GBCGDNIH2_RS00785 bb46de5b687e4eecc3118ccdbb652a5c 574 SUPERFAMILY SSF161098 372 559 1.44E-16 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GBCGDNIH2_RS08470 e302948bcf6e058e5ec41d09406271f2 1359 SUPERFAMILY SSF51120 973 1084 4.06E-11 T 29-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal GBCGDNIH2_RS08470 e302948bcf6e058e5ec41d09406271f2 1359 SUPERFAMILY SSF51120 1046 1163 6.15E-6 T 29-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal GBCGDNIH2_RS08470 e302948bcf6e058e5ec41d09406271f2 1359 Gene3D G3DSA:2.150.10.10 1066 1204 0.038 T 29-03-2018 GBCGDNIH2_RS08470 e302948bcf6e058e5ec41d09406271f2 1359 Gene3D G3DSA:2.150.10.10 1205 1357 2.9E-8 T 29-03-2018 GBCGDNIH2_RS08470 e302948bcf6e058e5ec41d09406271f2 1359 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 615 651 6.5E-8 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08470 e302948bcf6e058e5ec41d09406271f2 1359 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 652 689 3.7E-7 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08470 e302948bcf6e058e5ec41d09406271f2 1359 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 485 520 4.9E-5 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08470 e302948bcf6e058e5ec41d09406271f2 1359 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 391 425 6.9E-9 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08470 e302948bcf6e058e5ec41d09406271f2 1359 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 219 248 8.9E-7 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08470 e302948bcf6e058e5ec41d09406271f2 1359 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 244 266 1.1E-4 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08470 e302948bcf6e058e5ec41d09406271f2 1359 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 20 57 3.0E-10 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08470 e302948bcf6e058e5ec41d09406271f2 1359 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 522 558 7.0E-7 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08470 e302948bcf6e058e5ec41d09406271f2 1359 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 576 613 3.7E-7 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08470 e302948bcf6e058e5ec41d09406271f2 1359 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 173 209 1.5E-5 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08470 e302948bcf6e058e5ec41d09406271f2 1359 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 334 368 3.0E-7 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08470 e302948bcf6e058e5ec41d09406271f2 1359 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 59 92 1.9E-5 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08470 e302948bcf6e058e5ec41d09406271f2 1359 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 691 727 3.7E-13 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08470 e302948bcf6e058e5ec41d09406271f2 1359 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 729 762 2.3E-7 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08470 e302948bcf6e058e5ec41d09406271f2 1359 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 427 463 1.6E-8 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08470 e302948bcf6e058e5ec41d09406271f2 1359 Pfam PF16168 Adhesin of bacterial autotransporter system, probable stalk 228 277 5.3E-7 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08470 e302948bcf6e058e5ec41d09406271f2 1359 Pfam PF16168 Adhesin of bacterial autotransporter system, probable stalk 36 83 9.8E-7 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08470 e302948bcf6e058e5ec41d09406271f2 1359 Pfam PF16168 Adhesin of bacterial autotransporter system, probable stalk 611 662 9.0E-7 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08470 e302948bcf6e058e5ec41d09406271f2 1359 Pfam PF16168 Adhesin of bacterial autotransporter system, probable stalk 659 719 1.0E-7 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08470 e302948bcf6e058e5ec41d09406271f2 1359 SUPERFAMILY SSF51120 1163 1351 7.85E-10 T 29-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal GBCGDNIH2_RS08470 e302948bcf6e058e5ec41d09406271f2 1359 PRINTS PR00313 NodO calcium binding signature 1268 1277 7.5E-6 T 29-03-2018 GBCGDNIH2_RS08470 e302948bcf6e058e5ec41d09406271f2 1359 PRINTS PR00313 NodO calcium binding signature 1049 1057 7.5E-6 T 29-03-2018 GBCGDNIH2_RS08470 e302948bcf6e058e5ec41d09406271f2 1359 PRINTS PR00313 NodO calcium binding signature 1187 1195 7.5E-6 T 29-03-2018 GBCGDNIH2_RS08470 e302948bcf6e058e5ec41d09406271f2 1359 PRINTS PR00313 NodO calcium binding signature 1001 1012 7.5E-6 T 29-03-2018 GBCGDNIH2_RS07940 106a9f67cf51800592d6e5cf595e95c3 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.0E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS07940 106a9f67cf51800592d6e5cf595e95c3 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.0E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS07940 106a9f67cf51800592d6e5cf595e95c3 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.0E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS07940 106a9f67cf51800592d6e5cf595e95c3 290 Gene3D G3DSA:1.10.10.10 1 77 5.4E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS07940 106a9f67cf51800592d6e5cf595e95c3 290 SUPERFAMILY SSF53850 89 288 1.3E-41 T 29-03-2018 GBCGDNIH2_RS07940 106a9f67cf51800592d6e5cf595e95c3 290 Pfam PF03466 LysR substrate binding domain 89 286 6.8E-45 T 29-03-2018 IPR005119 LysR, substrate-binding GBCGDNIH2_RS07940 106a9f67cf51800592d6e5cf595e95c3 290 Gene3D G3DSA:3.40.190.10 178 264 1.0E-14 T 29-03-2018 GBCGDNIH2_RS07940 106a9f67cf51800592d6e5cf595e95c3 290 SUPERFAMILY SSF46785 1 111 5.15E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS07940 106a9f67cf51800592d6e5cf595e95c3 290 Gene3D G3DSA:3.40.190.10 78 177 1.7E-20 T 29-03-2018 GBCGDNIH2_RS07940 106a9f67cf51800592d6e5cf595e95c3 290 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.3E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS06165 f9e8b2201fb540b05207600e3ec54cc7 711 Gene3D G3DSA:3.40.50.740 358 517 1.1E-18 T 29-03-2018 GBCGDNIH2_RS06165 f9e8b2201fb540b05207600e3ec54cc7 711 Gene3D G3DSA:2.40.40.20 568 711 3.0E-27 T 29-03-2018 GBCGDNIH2_RS06165 f9e8b2201fb540b05207600e3ec54cc7 711 SUPERFAMILY SSF53706 12 584 2.09E-149 T 29-03-2018 GBCGDNIH2_RS06165 f9e8b2201fb540b05207600e3ec54cc7 711 Pfam PF01568 Molydopterin dinucleotide binding domain 598 701 2.8E-21 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 GBCGDNIH2_RS06165 f9e8b2201fb540b05207600e3ec54cc7 711 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 11 57 7.0E-10 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS06165 f9e8b2201fb540b05207600e3ec54cc7 711 Pfam PF00384 Molybdopterin oxidoreductase 68 476 7.6E-52 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS06165 f9e8b2201fb540b05207600e3ec54cc7 711 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 633 660 - T 29-03-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 GBCGDNIH2_RS06165 f9e8b2201fb540b05207600e3ec54cc7 711 SMART SM00926 10 65 1.4E-14 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS06165 f9e8b2201fb540b05207600e3ec54cc7 711 SUPERFAMILY SSF50692 589 709 4.29E-32 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain GBCGDNIH2_RS06165 f9e8b2201fb540b05207600e3ec54cc7 711 Gene3D G3DSA:3.40.50.740 69 167 2.4E-11 T 29-03-2018 GBCGDNIH2_RS06165 f9e8b2201fb540b05207600e3ec54cc7 711 Gene3D G3DSA:3.40.228.10 168 342 8.4E-55 T 29-03-2018 GBCGDNIH2_RS06165 f9e8b2201fb540b05207600e3ec54cc7 711 Gene3D G3DSA:2.20.25.90 3 68 3.8E-15 T 29-03-2018 GBCGDNIH2_RS06895 d64103631eaa30781beb432c3ae8a3ab 552 Gene3D G3DSA:3.40.50.10710 215 391 1.2E-32 T 29-03-2018 GBCGDNIH2_RS06895 d64103631eaa30781beb432c3ae8a3ab 552 SMART SM00849 20 226 1.2E-16 T 29-03-2018 IPR001279 Metallo-beta-lactamase GBCGDNIH2_RS06895 d64103631eaa30781beb432c3ae8a3ab 552 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 365 410 1.2E-9 T 29-03-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain GBCGDNIH2_RS06895 d64103631eaa30781beb432c3ae8a3ab 552 Gene3D G3DSA:3.60.15.10 1 214 2.0E-22 T 29-03-2018 IPR001279 Metallo-beta-lactamase GBCGDNIH2_RS06895 d64103631eaa30781beb432c3ae8a3ab 552 SUPERFAMILY SSF56281 10 423 2.36E-82 T 29-03-2018 IPR001279 Metallo-beta-lactamase GBCGDNIH2_RS06895 d64103631eaa30781beb432c3ae8a3ab 552 Pfam PF00753 Metallo-beta-lactamase superfamily 34 179 6.1E-11 T 29-03-2018 IPR001279 Metallo-beta-lactamase GBCGDNIH2_RS03455 bca113d869c103730fec15b73b0ec3da 273 Pfam PF01925 Sulfite exporter TauE/SafE 23 271 1.9E-38 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 GBCGDNIH2_RS01645 ccfbeeb74ed9fb3c081dcc1d802dc93a 127 Pfam PF01047 MarR family 32 88 2.8E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GBCGDNIH2_RS01645 ccfbeeb74ed9fb3c081dcc1d802dc93a 127 SMART SM00347 23 123 4.1E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GBCGDNIH2_RS01645 ccfbeeb74ed9fb3c081dcc1d802dc93a 127 Gene3D G3DSA:1.10.10.10 5 119 6.3E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS01645 ccfbeeb74ed9fb3c081dcc1d802dc93a 127 SUPERFAMILY SSF46785 25 113 2.95E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS00575 9da2be6291bec45f700cf6d6381584a3 209 Gene3D G3DSA:3.40.50.1000 1 207 4.1E-21 T 29-03-2018 IPR023214 HAD-like domain GBCGDNIH2_RS00575 9da2be6291bec45f700cf6d6381584a3 209 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 181 1.9E-7 T 29-03-2018 IPR023214 HAD-like domain GBCGDNIH2_RS00575 9da2be6291bec45f700cf6d6381584a3 209 SUPERFAMILY SSF56784 4 195 3.25E-28 T 29-03-2018 IPR023214 HAD-like domain GBCGDNIH2_RS00575 9da2be6291bec45f700cf6d6381584a3 209 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 124 182 7.4E-10 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 GBCGDNIH2_RS11695 dcf7cbed2dcfbf7177032ae267ec1d2d 317 Pfam PF01040 UbiA prenyltransferase family 44 282 2.5E-62 T 29-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 GBCGDNIH2_RS11695 dcf7cbed2dcfbf7177032ae267ec1d2d 317 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 30 314 1.8E-97 T 29-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 GBCGDNIH2_RS11695 dcf7cbed2dcfbf7177032ae267ec1d2d 317 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 81 103 - T 29-03-2018 IPR030470 UbiA prenyltransferase conserved site GBCGDNIH2_RS11695 dcf7cbed2dcfbf7177032ae267ec1d2d 317 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 27 316 20.042 T 29-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 GBCGDNIH2_RS06830 288e94047a9f210065ff6b8bc55426c1 396 SUPERFAMILY SSF111369 95 318 9.94E-11 T 29-03-2018 GBCGDNIH2_RS06830 288e94047a9f210065ff6b8bc55426c1 396 Gene3D G3DSA:2.40.50.100 95 244 4.0E-13 T 29-03-2018 GBCGDNIH2_RS06830 288e94047a9f210065ff6b8bc55426c1 396 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 82 311 1.2E-34 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain GBCGDNIH2_RS06830 288e94047a9f210065ff6b8bc55426c1 396 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 74 383 2.7E-31 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 GBCGDNIH2_RS10460 5e69a60401a8a211e013ee1f4e378052 408 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 80 99 2.5E-19 T 29-03-2018 GBCGDNIH2_RS10460 5e69a60401a8a211e013ee1f4e378052 408 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 227 245 2.5E-19 T 29-03-2018 GBCGDNIH2_RS10460 5e69a60401a8a211e013ee1f4e378052 408 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 182 200 2.5E-19 T 29-03-2018 GBCGDNIH2_RS10460 5e69a60401a8a211e013ee1f4e378052 408 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 341 363 2.5E-19 T 29-03-2018 GBCGDNIH2_RS10460 5e69a60401a8a211e013ee1f4e378052 408 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 351 369 5.2E-25 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 GBCGDNIH2_RS10460 5e69a60401a8a211e013ee1f4e378052 408 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 183 191 5.2E-25 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 GBCGDNIH2_RS10460 5e69a60401a8a211e013ee1f4e378052 408 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 223 247 5.2E-25 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 GBCGDNIH2_RS10460 5e69a60401a8a211e013ee1f4e378052 408 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 136 146 5.2E-25 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 GBCGDNIH2_RS10460 5e69a60401a8a211e013ee1f4e378052 408 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 79 101 5.2E-25 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 GBCGDNIH2_RS10460 5e69a60401a8a211e013ee1f4e378052 408 SUPERFAMILY SSF51905 69 387 4.4E-41 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS10460 5e69a60401a8a211e013ee1f4e378052 408 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 79 368 1.4E-30 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS10460 5e69a60401a8a211e013ee1f4e378052 408 Gene3D G3DSA:3.50.50.60 67 259 3.5E-27 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS10460 5e69a60401a8a211e013ee1f4e378052 408 Gene3D G3DSA:3.50.50.60 260 394 5.7E-13 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS10460 5e69a60401a8a211e013ee1f4e378052 408 Hamap MF_01685 Ferredoxin--NADP reductase. 77 404 41.001 T 29-03-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 GBCGDNIH2_RS05600 7fcc03165aa82b9d7314a5951168c59c 741 Pfam PF00593 TonB dependent receptor 271 740 1.5E-54 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 GBCGDNIH2_RS05600 7fcc03165aa82b9d7314a5951168c59c 741 Gene3D G3DSA:2.40.170.20 214 741 2.1E-74 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 GBCGDNIH2_RS05600 7fcc03165aa82b9d7314a5951168c59c 741 SUPERFAMILY SSF56935 87 741 7.59E-119 T 29-03-2018 GBCGDNIH2_RS05600 7fcc03165aa82b9d7314a5951168c59c 741 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 724 741 - T 29-03-2018 IPR010917 TonB-dependent receptor, conserved site GBCGDNIH2_RS05600 7fcc03165aa82b9d7314a5951168c59c 741 Pfam PF07715 TonB-dependent Receptor Plug Domain 95 199 6.4E-18 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 GBCGDNIH2_RS05600 7fcc03165aa82b9d7314a5951168c59c 741 Gene3D G3DSA:2.170.130.10 94 213 1.4E-20 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 GBCGDNIH2_RS05600 7fcc03165aa82b9d7314a5951168c59c 741 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 97 741 3.7E-71 T 29-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 GBCGDNIH2_RS11320 4d30f2ae5dde6c337c2fd3090eee5b31 96 Hamap MF_00580 10 kDa chaperonin [groS]. 3 96 27.306 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 GBCGDNIH2_RS11320 4d30f2ae5dde6c337c2fd3090eee5b31 96 Pfam PF00166 Chaperonin 10 Kd subunit 4 95 9.6E-37 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 GBCGDNIH2_RS11320 4d30f2ae5dde6c337c2fd3090eee5b31 96 SMART SM00883 3 95 1.1E-61 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 GBCGDNIH2_RS11320 4d30f2ae5dde6c337c2fd3090eee5b31 96 SUPERFAMILY SSF50129 2 95 6.59E-36 T 29-03-2018 IPR011032 GroES-like GBCGDNIH2_RS11320 4d30f2ae5dde6c337c2fd3090eee5b31 96 ProSitePatterns PS00681 Chaperonins cpn10 signature. 4 28 - T 29-03-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 GBCGDNIH2_RS11320 4d30f2ae5dde6c337c2fd3090eee5b31 96 Gene3D G3DSA:2.30.33.40 2 96 1.5E-39 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 GBCGDNIH2_RS11320 4d30f2ae5dde6c337c2fd3090eee5b31 96 PRINTS PR00297 10kDa chaperonin signature 26 47 1.7E-33 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 GBCGDNIH2_RS11320 4d30f2ae5dde6c337c2fd3090eee5b31 96 PRINTS PR00297 10kDa chaperonin signature 82 95 1.7E-33 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 GBCGDNIH2_RS11320 4d30f2ae5dde6c337c2fd3090eee5b31 96 PRINTS PR00297 10kDa chaperonin signature 61 73 1.7E-33 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 GBCGDNIH2_RS11320 4d30f2ae5dde6c337c2fd3090eee5b31 96 PRINTS PR00297 10kDa chaperonin signature 4 19 1.7E-33 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 GBCGDNIH2_RS10880 526b0de65b4e6b28ca21719a2368eeba 172 SMART SM00422 17 86 6.9E-27 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 GBCGDNIH2_RS10880 526b0de65b4e6b28ca21719a2368eeba 172 Gene3D G3DSA:1.10.1660.10 14 73 7.1E-21 T 29-03-2018 GBCGDNIH2_RS10880 526b0de65b4e6b28ca21719a2368eeba 172 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 29 42 1.4E-9 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 GBCGDNIH2_RS10880 526b0de65b4e6b28ca21719a2368eeba 172 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 18 29 1.4E-9 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 GBCGDNIH2_RS10880 526b0de65b4e6b28ca21719a2368eeba 172 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 53 73 1.4E-9 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 GBCGDNIH2_RS10880 526b0de65b4e6b28ca21719a2368eeba 172 SUPERFAMILY SSF46955 18 142 1.39E-34 T 29-03-2018 IPR009061 Putative DNA-binding domain GBCGDNIH2_RS10880 526b0de65b4e6b28ca21719a2368eeba 172 Pfam PF13411 MerR HTH family regulatory protein 19 83 3.8E-17 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 GBCGDNIH2_RS10880 526b0de65b4e6b28ca21719a2368eeba 172 Gene3D G3DSA:1.10.1660.10 74 153 2.3E-16 T 29-03-2018 GBCGDNIH2_RS02465 e094e838a90defc402c1b61937a8188a 350 Gene3D G3DSA:3.40.50.2000 8 187 2.4E-4 T 29-03-2018 GBCGDNIH2_RS02465 e094e838a90defc402c1b61937a8188a 350 SUPERFAMILY SSF53756 11 338 3.69E-56 T 29-03-2018 GBCGDNIH2_RS02465 e094e838a90defc402c1b61937a8188a 350 Pfam PF00534 Glycosyl transferases group 1 167 311 9.3E-24 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 GBCGDNIH2_RS02465 e094e838a90defc402c1b61937a8188a 350 Pfam PF13439 Glycosyltransferase Family 4 18 119 3.8E-10 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 GBCGDNIH2_RS02465 e094e838a90defc402c1b61937a8188a 350 Gene3D G3DSA:3.40.50.2000 188 326 4.5E-24 T 29-03-2018 GBCGDNIH2_RS06790 c02707f4e6a02ed92030aa55d63747f1 257 SUPERFAMILY SSF56219 2 255 2.62E-69 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase GBCGDNIH2_RS06790 c02707f4e6a02ed92030aa55d63747f1 257 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 255 2.1E-62 T 29-03-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 GBCGDNIH2_RS06790 c02707f4e6a02ed92030aa55d63747f1 257 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 248 2.4E-22 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase GBCGDNIH2_RS06790 c02707f4e6a02ed92030aa55d63747f1 257 Gene3D G3DSA:3.60.10.10 1 256 1.0E-42 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase GBCGDNIH2_RS06790 c02707f4e6a02ed92030aa55d63747f1 257 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 2 255 2.0E-59 T 29-03-2018 GBCGDNIH2_RS06790 c02707f4e6a02ed92030aa55d63747f1 257 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 27 36 - T 29-03-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 GBCGDNIH2_RS10510 e086a5f10fa83561a2742754b9f5a1a3 408 Gene3D G3DSA:3.40.50.1100 212 406 8.3E-39 T 29-03-2018 GBCGDNIH2_RS10510 e086a5f10fa83561a2742754b9f5a1a3 408 PIRSF PIRSF001413 8 408 7.5E-161 T 29-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 GBCGDNIH2_RS10510 e086a5f10fa83561a2742754b9f5a1a3 408 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 15 404 52.902 T 29-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 GBCGDNIH2_RS10510 e086a5f10fa83561a2742754b9f5a1a3 408 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 94 108 - T 29-03-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 GBCGDNIH2_RS10510 e086a5f10fa83561a2742754b9f5a1a3 408 Gene3D G3DSA:3.40.50.1100 22 80 3.3E-7 T 29-03-2018 GBCGDNIH2_RS10510 e086a5f10fa83561a2742754b9f5a1a3 408 Gene3D G3DSA:3.40.50.1100 81 211 1.2E-39 T 29-03-2018 GBCGDNIH2_RS10510 e086a5f10fa83561a2742754b9f5a1a3 408 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 20 403 9.4E-194 T 29-03-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 GBCGDNIH2_RS10510 e086a5f10fa83561a2742754b9f5a1a3 408 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 66 391 6.5E-48 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme GBCGDNIH2_RS10510 e086a5f10fa83561a2742754b9f5a1a3 408 SUPERFAMILY SSF53686 16 403 1.24E-149 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme GBCGDNIH2_RS00035 67af05984ef97be20df45ef532895b82 351 Gene3D G3DSA:1.20.272.10 208 340 2.2E-13 T 29-03-2018 GBCGDNIH2_RS00035 67af05984ef97be20df45ef532895b82 351 Gene3D G3DSA:3.40.50.300 1 133 4.1E-7 T 29-03-2018 GBCGDNIH2_RS00035 67af05984ef97be20df45ef532895b82 351 Gene3D G3DSA:1.10.8.60 138 205 3.1E-12 T 29-03-2018 GBCGDNIH2_RS00035 67af05984ef97be20df45ef532895b82 351 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 21 329 1.0E-36 T 29-03-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 GBCGDNIH2_RS00035 67af05984ef97be20df45ef532895b82 351 SUPERFAMILY SSF52540 9 203 1.12E-7 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS00035 67af05984ef97be20df45ef532895b82 351 SUPERFAMILY SSF48019 217 330 1.46E-12 T 29-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 GBCGDNIH2_RS10660 63a2d351b641ac9175ae6c2cc7fe857c 219 ProSitePatterns PS00159 KDPG and KHG aldolases active site. 38 47 - T 29-03-2018 IPR031337 KDPG/KHG aldolase, active site 1 KEGG: 00030+4.1.2.14|KEGG: 00330+4.1.3.16|KEGG: 00630+4.1.3.16|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 GBCGDNIH2_RS10660 63a2d351b641ac9175ae6c2cc7fe857c 219 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 8 205 1.6E-65 T 29-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 GBCGDNIH2_RS10660 63a2d351b641ac9175ae6c2cc7fe857c 219 Pfam PF01081 KDPG and KHG aldolase 9 199 1.7E-60 T 29-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 GBCGDNIH2_RS10660 63a2d351b641ac9175ae6c2cc7fe857c 219 SUPERFAMILY SSF51569 3 204 8.06E-58 T 29-03-2018 GBCGDNIH2_RS10660 63a2d351b641ac9175ae6c2cc7fe857c 219 Gene3D G3DSA:3.20.20.70 5 205 7.9E-27 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS10995 ba1333613158fedd3c94d85746e569f2 297 Pfam PF13522 Glutamine amidotransferase domain 139 268 1.8E-17 T 29-03-2018 GBCGDNIH2_RS10995 ba1333613158fedd3c94d85746e569f2 297 SUPERFAMILY SSF56235 114 294 1.48E-40 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal GBCGDNIH2_RS10995 ba1333613158fedd3c94d85746e569f2 297 SUPERFAMILY SSF56235 2 43 1.48E-40 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal GBCGDNIH2_RS10995 ba1333613158fedd3c94d85746e569f2 297 Gene3D G3DSA:3.60.20.10 2 297 2.4E-45 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal GBCGDNIH2_RS02265 6a22684aa8a103cc79360ea678ea17b5 250 SUPERFAMILY SSF47090 186 237 5.34E-9 T 29-03-2018 IPR002477 Peptidoglycan binding-like GBCGDNIH2_RS02265 6a22684aa8a103cc79360ea678ea17b5 250 SMART SM00644 19 158 1.5E-35 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 GBCGDNIH2_RS02265 6a22684aa8a103cc79360ea678ea17b5 250 Gene3D G3DSA:3.40.80.10 31 172 8.2E-43 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 GBCGDNIH2_RS02265 6a22684aa8a103cc79360ea678ea17b5 250 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 32 158 3.3E-29 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 GBCGDNIH2_RS02265 6a22684aa8a103cc79360ea678ea17b5 250 SUPERFAMILY SSF55846 9 174 9.68E-54 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 GBCGDNIH2_RS03180 d192a7b5bd7584dddeedfd1a113b4f95 409 Gene3D G3DSA:3.60.70.12 13 281 2.9E-103 T 29-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 GBCGDNIH2_RS03180 d192a7b5bd7584dddeedfd1a113b4f95 409 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 20 409 7.5E-120 T 29-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 GBCGDNIH2_RS03180 d192a7b5bd7584dddeedfd1a113b4f95 409 SUPERFAMILY SSF56266 19 405 1.05E-140 T 29-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 GBCGDNIH2_RS03180 d192a7b5bd7584dddeedfd1a113b4f95 409 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 29 407 1.0E-131 T 29-03-2018 GBCGDNIH2_RS03180 d192a7b5bd7584dddeedfd1a113b4f95 409 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 409 155.088 T 29-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 GBCGDNIH2_RS03180 d192a7b5bd7584dddeedfd1a113b4f95 409 Pfam PF01960 ArgJ family 24 409 7.1E-145 T 29-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 GBCGDNIH2_RS00495 4a52661acc402cd0379055ba80e8a304 306 Gene3D G3DSA:3.30.70.1350 213 303 2.6E-26 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain GBCGDNIH2_RS00495 4a52661acc402cd0379055ba80e8a304 306 Pfam PF01545 Cation efflux family 23 213 6.2E-38 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 GBCGDNIH2_RS00495 4a52661acc402cd0379055ba80e8a304 306 Gene3D G3DSA:1.20.1510.10 14 212 8.5E-37 T 29-03-2018 GBCGDNIH2_RS00495 4a52661acc402cd0379055ba80e8a304 306 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 22 295 2.5E-64 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 GBCGDNIH2_RS00495 4a52661acc402cd0379055ba80e8a304 306 SUPERFAMILY SSF161111 13 215 3.79E-51 T 29-03-2018 GBCGDNIH2_RS00495 4a52661acc402cd0379055ba80e8a304 306 SUPERFAMILY SSF160240 216 294 2.35E-21 T 29-03-2018 GBCGDNIH2_RS00495 4a52661acc402cd0379055ba80e8a304 306 Pfam PF16916 Dimerisation domain of Zinc Transporter 219 294 8.5E-24 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain GBCGDNIH2_RS03840 e42fd75792e5ae55e8515701994bb505 607 Gene3D G3DSA:3.40.50.300 250 501 1.8E-50 T 29-03-2018 GBCGDNIH2_RS03840 e42fd75792e5ae55e8515701994bb505 607 Pfam PF00005 ABC transporter 299 433 1.5E-22 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GBCGDNIH2_RS03840 e42fd75792e5ae55e8515701994bb505 607 Pfam PF00005 ABC transporter 23 148 3.4E-22 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GBCGDNIH2_RS03840 e42fd75792e5ae55e8515701994bb505 607 Gene3D G3DSA:3.40.50.300 5 249 2.1E-44 T 29-03-2018 GBCGDNIH2_RS03840 e42fd75792e5ae55e8515701994bb505 607 SUPERFAMILY SSF52540 4 194 1.6E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS03840 e42fd75792e5ae55e8515701994bb505 607 SMART SM00382 30 194 3.2E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS03840 e42fd75792e5ae55e8515701994bb505 607 SMART SM00382 307 478 2.7E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS03840 e42fd75792e5ae55e8515701994bb505 607 Pfam PF16326 ABC transporter C-terminal domain 530 596 8.2E-17 T 29-03-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 GBCGDNIH2_RS03840 e42fd75792e5ae55e8515701994bb505 607 SUPERFAMILY SSF52540 273 479 1.14E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS09360 86c72d76718ea42309c54290e55a2db0 285 Pfam PF14082 Domain of unknown function (DUF4263) 98 265 1.3E-31 T 29-03-2018 IPR025359 Protein of unknown function DUF4263 GBCGDNIH2_RS08855 955862a665509a7a8dc9603edfe6719e 186 Gene3D G3DSA:2.40.30.60 4 89 2.6E-15 T 29-03-2018 IPR002676 RimM protein GO:0006364 GBCGDNIH2_RS08855 955862a665509a7a8dc9603edfe6719e 186 SUPERFAMILY SSF50447 4 89 3.53E-13 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain GBCGDNIH2_RS08855 955862a665509a7a8dc9603edfe6719e 186 Pfam PF01782 RimM N-terminal domain 8 86 1.2E-13 T 29-03-2018 IPR002676 RimM protein GO:0006364 GBCGDNIH2_RS08855 955862a665509a7a8dc9603edfe6719e 186 Gene3D G3DSA:2.30.30.240 92 162 1.2E-18 T 29-03-2018 GBCGDNIH2_RS08855 955862a665509a7a8dc9603edfe6719e 186 SUPERFAMILY SSF50346 96 165 1.18E-12 T 29-03-2018 IPR011033 PRC-barrel-like GBCGDNIH2_RS08855 955862a665509a7a8dc9603edfe6719e 186 Pfam PF05239 PRC-barrel domain 93 166 1.4E-4 T 29-03-2018 IPR027275 PRC-barrel domain GBCGDNIH2_RS08855 955862a665509a7a8dc9603edfe6719e 186 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 5 167 20.316 T 29-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 GBCGDNIH2_RS08855 955862a665509a7a8dc9603edfe6719e 186 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 6 165 1.1E-30 T 29-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 GBCGDNIH2_RS03860 2c75260e82060c2bcc6943155d4dd81d 596 SMART SM00642 116 456 2.0E-8 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 GBCGDNIH2_RS03860 2c75260e82060c2bcc6943155d4dd81d 596 SUPERFAMILY SSF51445 91 510 9.27E-102 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily GBCGDNIH2_RS03860 2c75260e82060c2bcc6943155d4dd81d 596 PIRSF PIRSF006337 6 588 2.0E-209 T 29-03-2018 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00500+3.2.1.141|KEGG: 00520+3.2.1.14|MetaCyc: PWY-2661|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 GBCGDNIH2_RS03860 2c75260e82060c2bcc6943155d4dd81d 596 Gene3D G3DSA:2.60.40.10 2 94 2.9E-14 T 29-03-2018 IPR013783 Immunoglobulin-like fold GBCGDNIH2_RS03860 2c75260e82060c2bcc6943155d4dd81d 596 Pfam PF00128 Alpha amylase, catalytic domain 227 427 4.2E-5 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 GBCGDNIH2_RS03860 2c75260e82060c2bcc6943155d4dd81d 596 Pfam PF00128 Alpha amylase, catalytic domain 123 213 1.6E-13 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 GBCGDNIH2_RS03860 2c75260e82060c2bcc6943155d4dd81d 596 Gene3D G3DSA:1.10.10.760 446 479 4.5E-17 T 29-03-2018 GBCGDNIH2_RS03860 2c75260e82060c2bcc6943155d4dd81d 596 Gene3D G3DSA:2.60.40.1180 524 589 2.7E-15 T 29-03-2018 GBCGDNIH2_RS03860 2c75260e82060c2bcc6943155d4dd81d 596 Gene3D G3DSA:3.20.20.80 221 445 7.0E-29 T 29-03-2018 GBCGDNIH2_RS03860 2c75260e82060c2bcc6943155d4dd81d 596 Gene3D G3DSA:3.20.20.80 110 220 3.9E-29 T 29-03-2018 GBCGDNIH2_RS03860 2c75260e82060c2bcc6943155d4dd81d 596 TIGRFAM TIGR02402 trehalose_TreZ: malto-oligosyltrehalose trehalohydrolase 19 557 2.3E-199 T 29-03-2018 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00500+3.2.1.141|KEGG: 00520+3.2.1.14|MetaCyc: PWY-2661|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 GBCGDNIH2_RS03860 2c75260e82060c2bcc6943155d4dd81d 596 SUPERFAMILY SSF81296 11 94 7.4E-15 T 29-03-2018 IPR014756 Immunoglobulin E-set GBCGDNIH2_RS03860 2c75260e82060c2bcc6943155d4dd81d 596 Pfam PF11941 Domain of unknown function (DUF3459) 502 586 2.4E-17 T 29-03-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) GBCGDNIH2_RS12065 1e52759ee6992c5303bc1a9b6c338771 909 Gene3D G3DSA:3.40.50.2300 774 907 5.6E-25 T 29-03-2018 GBCGDNIH2_RS12065 1e52759ee6992c5303bc1a9b6c338771 909 Gene3D G3DSA:3.40.50.2300 624 767 1.0E-23 T 29-03-2018 GBCGDNIH2_RS12065 1e52759ee6992c5303bc1a9b6c338771 909 Gene3D G3DSA:3.30.450.20 56 170 9.4E-10 T 29-03-2018 GBCGDNIH2_RS12065 1e52759ee6992c5303bc1a9b6c338771 909 Gene3D G3DSA:1.10.287.130 369 441 1.3E-5 T 29-03-2018 GBCGDNIH2_RS12065 1e52759ee6992c5303bc1a9b6c338771 909 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 488 607 4.4E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS12065 1e52759ee6992c5303bc1a9b6c338771 909 Gene3D G3DSA:3.30.565.10 445 609 3.7E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS12065 1e52759ee6992c5303bc1a9b6c338771 909 PRINTS PR00344 Bacterial sensor protein C-terminal signature 538 552 2.1E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS12065 1e52759ee6992c5303bc1a9b6c338771 909 PRINTS PR00344 Bacterial sensor protein C-terminal signature 556 566 2.1E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS12065 1e52759ee6992c5303bc1a9b6c338771 909 PRINTS PR00344 Bacterial sensor protein C-terminal signature 593 606 2.1E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS12065 1e52759ee6992c5303bc1a9b6c338771 909 PRINTS PR00344 Bacterial sensor protein C-terminal signature 569 587 2.1E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS12065 1e52759ee6992c5303bc1a9b6c338771 909 SUPERFAMILY SSF52172 782 902 1.71E-27 T 29-03-2018 IPR011006 CheY-like superfamily GBCGDNIH2_RS12065 1e52759ee6992c5303bc1a9b6c338771 909 Pfam PF08448 PAS fold 76 171 5.4E-8 T 29-03-2018 IPR013656 PAS fold-4 GBCGDNIH2_RS12065 1e52759ee6992c5303bc1a9b6c338771 909 SMART SM00448 631 742 7.2E-19 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GBCGDNIH2_RS12065 1e52759ee6992c5303bc1a9b6c338771 909 SMART SM00448 783 893 1.1E-18 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GBCGDNIH2_RS12065 1e52759ee6992c5303bc1a9b6c338771 909 SUPERFAMILY SSF52172 632 746 3.98E-26 T 29-03-2018 IPR011006 CheY-like superfamily GBCGDNIH2_RS12065 1e52759ee6992c5303bc1a9b6c338771 909 Gene3D G3DSA:3.30.450.40 171 368 2.3E-10 T 29-03-2018 IPR029016 GAF domain-like GBCGDNIH2_RS12065 1e52759ee6992c5303bc1a9b6c338771 909 SMART SM00387 486 609 2.9E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS12065 1e52759ee6992c5303bc1a9b6c338771 909 SUPERFAMILY SSF55874 435 607 6.16E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS12065 1e52759ee6992c5303bc1a9b6c338771 909 SUPERFAMILY SSF47384 365 442 2.75E-7 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GBCGDNIH2_RS12065 1e52759ee6992c5303bc1a9b6c338771 909 Pfam PF00072 Response regulator receiver domain 633 742 1.4E-16 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GBCGDNIH2_RS12065 1e52759ee6992c5303bc1a9b6c338771 909 Pfam PF00072 Response regulator receiver domain 785 892 1.7E-15 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GBCGDNIH2_RS12065 1e52759ee6992c5303bc1a9b6c338771 909 SUPERFAMILY SSF55781 258 350 3.92E-5 T 29-03-2018 IPR029016 GAF domain-like GBCGDNIH2_RS10780 ef84f968de0fe57bfcd74cb8ffd49c3d 398 Pfam PF00549 CoA-ligase 271 390 2.1E-26 T 29-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 GBCGDNIH2_RS10780 ef84f968de0fe57bfcd74cb8ffd49c3d 398 Gene3D G3DSA:3.30.1490.20 21 104 2.1E-22 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 GBCGDNIH2_RS10780 ef84f968de0fe57bfcd74cb8ffd49c3d 398 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 395 43.96 T 29-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 GBCGDNIH2_RS10780 ef84f968de0fe57bfcd74cb8ffd49c3d 398 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 266 290 - T 29-03-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 GBCGDNIH2_RS10780 ef84f968de0fe57bfcd74cb8ffd49c3d 398 Gene3D G3DSA:3.40.50.261 249 394 5.8E-45 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 GBCGDNIH2_RS10780 ef84f968de0fe57bfcd74cb8ffd49c3d 398 PIRSF PIRSF001554 1 397 1.1E-149 T 29-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 GBCGDNIH2_RS10780 ef84f968de0fe57bfcd74cb8ffd49c3d 398 SUPERFAMILY SSF56059 2 247 3.91E-81 T 29-03-2018 GBCGDNIH2_RS10780 ef84f968de0fe57bfcd74cb8ffd49c3d 398 Pfam PF08442 ATP-grasp domain 2 212 3.2E-75 T 29-03-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 GBCGDNIH2_RS10780 ef84f968de0fe57bfcd74cb8ffd49c3d 398 SUPERFAMILY SSF52210 248 393 4.97E-55 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 GBCGDNIH2_RS10780 ef84f968de0fe57bfcd74cb8ffd49c3d 398 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 2 394 8.7E-156 T 29-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 GBCGDNIH2_RS10780 ef84f968de0fe57bfcd74cb8ffd49c3d 398 Gene3D G3DSA:3.30.470.20 105 248 1.7E-54 T 29-03-2018 GBCGDNIH2_RS12650 da8ef7fd8b0777bb6afad6cd9f8e1b11 333 Gene3D G3DSA:3.40.50.150 157 326 1.0E-10 T 29-03-2018 GBCGDNIH2_RS12650 da8ef7fd8b0777bb6afad6cd9f8e1b11 333 Pfam PF05711 Macrocin-O-methyltransferase (TylF) 160 311 5.2E-23 T 29-03-2018 IPR008884 Macrocin-O-methyltransferase GBCGDNIH2_RS12650 da8ef7fd8b0777bb6afad6cd9f8e1b11 333 SUPERFAMILY SSF53335 157 318 2.6E-9 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GBCGDNIH2_RS09105 0bb0dc083287e26190de4ede3041f05d 147 Pfam PF05071 NADH ubiquinone oxidoreductase subunit NDUFA12 43 145 5.2E-25 T 29-03-2018 IPR007763 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 GO:0008137|GO:0009055|GO:0016020 Reactome: R-HSA-6799198 GBCGDNIH2_RS08950 fa5f4b2c79985031d25e70ae7f069f4f 343 SUPERFAMILY SSF52540 150 332 3.68E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS08950 fa5f4b2c79985031d25e70ae7f069f4f 343 Gene3D G3DSA:3.40.50.300 159 339 4.3E-30 T 29-03-2018 GBCGDNIH2_RS08950 fa5f4b2c79985031d25e70ae7f069f4f 343 SUPERFAMILY SSF82051 2 158 3.27E-54 T 29-03-2018 IPR006169 GTP1/OBG domain GBCGDNIH2_RS08950 fa5f4b2c79985031d25e70ae7f069f4f 343 Gene3D G3DSA:2.70.210.12 2 156 6.4E-56 T 29-03-2018 IPR006169 GTP1/OBG domain GBCGDNIH2_RS08950 fa5f4b2c79985031d25e70ae7f069f4f 343 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 211 226 3.8E-34 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 GBCGDNIH2_RS08950 fa5f4b2c79985031d25e70ae7f069f4f 343 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 3.8E-34 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 GBCGDNIH2_RS08950 fa5f4b2c79985031d25e70ae7f069f4f 343 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 228 246 3.8E-34 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 GBCGDNIH2_RS08950 fa5f4b2c79985031d25e70ae7f069f4f 343 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 3.8E-34 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 GBCGDNIH2_RS08950 fa5f4b2c79985031d25e70ae7f069f4f 343 ProSitePatterns PS00905 GTP1/OBG family signature. 213 226 - T 29-03-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 GBCGDNIH2_RS08950 fa5f4b2c79985031d25e70ae7f069f4f 343 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 3 327 8.1E-137 T 29-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 GBCGDNIH2_RS08950 fa5f4b2c79985031d25e70ae7f069f4f 343 Pfam PF01926 50S ribosome-binding GTPase 162 281 6.0E-24 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 GBCGDNIH2_RS08950 fa5f4b2c79985031d25e70ae7f069f4f 343 PIRSF PIRSF002401 1 342 4.1E-129 T 29-03-2018 IPR035101 GTP-binding protein, Obg-type GBCGDNIH2_RS08950 fa5f4b2c79985031d25e70ae7f069f4f 343 Pfam PF01018 GTP1/OBG 5 158 1.0E-58 T 29-03-2018 IPR006169 GTP1/OBG domain GBCGDNIH2_RS08950 fa5f4b2c79985031d25e70ae7f069f4f 343 Hamap MF_01454 GTPase Obg [obg]. 2 328 45.453 T 29-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 GBCGDNIH2_RS05750 df0978b092e108e868916b5d76d9d459 229 SUPERFAMILY SSF54427 94 228 2.1E-29 T 29-03-2018 IPR032710 NTF2-like domain GBCGDNIH2_RS05750 df0978b092e108e868916b5d76d9d459 229 Pfam PF04335 VirB8 protein 23 226 1.4E-71 T 29-03-2018 IPR007430 Bacterial virulence protein VirB8 GO:0016020 GBCGDNIH2_RS11485 6302693ae38384df508f319f1552c05a 191 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 4 150 24.644 T 29-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS11485 6302693ae38384df508f319f1552c05a 191 ProSitePatterns PS00651 Ribosomal protein L9 signature. 16 43 - T 29-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS11485 6302693ae38384df508f319f1552c05a 191 Gene3D G3DSA:3.10.430.100 66 149 2.0E-23 T 29-03-2018 IPR020069 Ribosomal protein L9, C-terminal GBCGDNIH2_RS11485 6302693ae38384df508f319f1552c05a 191 SUPERFAMILY SSF55658 4 60 1.33E-17 T 29-03-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal GBCGDNIH2_RS11485 6302693ae38384df508f319f1552c05a 191 TIGRFAM TIGR00158 L9: ribosomal protein bL9 5 148 3.3E-38 T 29-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS11485 6302693ae38384df508f319f1552c05a 191 SUPERFAMILY SSF55653 60 149 1.27E-23 T 29-03-2018 IPR020069 Ribosomal protein L9, C-terminal GBCGDNIH2_RS11485 6302693ae38384df508f319f1552c05a 191 Gene3D G3DSA:3.40.5.10 5 52 4.2E-20 T 29-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS11485 6302693ae38384df508f319f1552c05a 191 Pfam PF03948 Ribosomal protein L9, C-terminal domain 66 148 1.7E-22 T 29-03-2018 IPR020069 Ribosomal protein L9, C-terminal GBCGDNIH2_RS11485 6302693ae38384df508f319f1552c05a 191 Pfam PF01281 Ribosomal protein L9, N-terminal domain 5 50 5.9E-19 T 29-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS07650 b23665b01d312a5c8b1db2d232f4c339 153 Pfam PF05443 ROS/MUCR transcriptional regulator protein 10 129 6.7E-49 T 29-03-2018 IPR008807 ROSMUCR transcriptional regulator GO:0003677|GO:0006355|GO:0008270 GBCGDNIH2_RS10225 aae93147fdd465207c77bf822586415f 161 Pfam PF00364 Biotin-requiring enzyme 88 160 7.4E-17 T 29-03-2018 IPR000089 Biotin/lipoyl attachment GBCGDNIH2_RS10225 aae93147fdd465207c77bf822586415f 161 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 117 134 - T 29-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 GBCGDNIH2_RS10225 aae93147fdd465207c77bf822586415f 161 SUPERFAMILY SSF51230 86 161 1.27E-20 T 29-03-2018 IPR011053 Single hybrid motif GBCGDNIH2_RS10225 aae93147fdd465207c77bf822586415f 161 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 107 121 1.2E-9 T 29-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 GBCGDNIH2_RS10225 aae93147fdd465207c77bf822586415f 161 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 90 103 1.2E-9 T 29-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 GBCGDNIH2_RS10225 aae93147fdd465207c77bf822586415f 161 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 122 135 1.2E-9 T 29-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 GBCGDNIH2_RS10225 aae93147fdd465207c77bf822586415f 161 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 8 161 1.2E-35 T 29-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 GBCGDNIH2_RS10225 aae93147fdd465207c77bf822586415f 161 Gene3D G3DSA:2.40.50.100 24 161 3.3E-16 T 29-03-2018 GBCGDNIH2_RS07790 54dd2ba676c2de3028b0d3af863b80c7 175 Pfam PF09917 Uncharacterized protein conserved in bacteria (DUF2147) 43 157 6.3E-21 T 29-03-2018 IPR019223 Domain of unknown function DUF2147 GBCGDNIH2_RS02315 8779a18495aa5aaea0c4e97dfa385e5a 553 Pfam PF07396 Phosphate-selective porin O and P 207 551 1.3E-41 T 29-03-2018 IPR010870 Phosphate-selective porin O/P GBCGDNIH2_RS02315 8779a18495aa5aaea0c4e97dfa385e5a 553 Gene3D G3DSA:2.40.160.10 131 553 5.9E-36 T 29-03-2018 GBCGDNIH2_RS08845 7d8cccf657d3c7d61e2899d708ca82fd 129 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 1 117 2.6E-46 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS08845 7d8cccf657d3c7d61e2899d708ca82fd 129 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 1 118 30.264 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS08845 7d8cccf657d3c7d61e2899d708ca82fd 129 Pfam PF01245 Ribosomal protein L19 2 117 7.8E-47 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS08845 7d8cccf657d3c7d61e2899d708ca82fd 129 SUPERFAMILY SSF50104 1 121 5.31E-46 T 29-03-2018 IPR008991 Translation protein SH3-like domain GBCGDNIH2_RS08845 7d8cccf657d3c7d61e2899d708ca82fd 129 PIRSF PIRSF002191 1 129 3.1E-53 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS08845 7d8cccf657d3c7d61e2899d708ca82fd 129 PRINTS PR00061 Ribosomal protein L19 signature 8 37 2.8E-34 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS08845 7d8cccf657d3c7d61e2899d708ca82fd 129 PRINTS PR00061 Ribosomal protein L19 signature 38 67 2.8E-34 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS08845 7d8cccf657d3c7d61e2899d708ca82fd 129 PRINTS PR00061 Ribosomal protein L19 signature 92 117 2.8E-34 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS08845 7d8cccf657d3c7d61e2899d708ca82fd 129 ProSitePatterns PS01015 Ribosomal protein L19 signature. 90 105 - T 29-03-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS00605 9095fe49dd4b09db61518475d7ef9a48 320 SUPERFAMILY SSF69593 52 306 1.44E-29 T 29-03-2018 GBCGDNIH2_RS00605 9095fe49dd4b09db61518475d7ef9a48 320 Pfam PF01553 Acyltransferase 115 228 4.4E-21 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 GBCGDNIH2_RS00605 9095fe49dd4b09db61518475d7ef9a48 320 Gene3D G3DSA:3.40.1130.10 77 309 1.3E-30 T 29-03-2018 GBCGDNIH2_RS00605 9095fe49dd4b09db61518475d7ef9a48 320 SMART SM00563 119 231 7.3E-27 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 GBCGDNIH2_RS08630 1a09c398d9daedc68e4de0f75c3db0bf 309 Gene3D G3DSA:3.40.50.410 64 273 8.6E-6 T 29-03-2018 IPR002035 von Willebrand factor, type A GBCGDNIH2_RS08630 1a09c398d9daedc68e4de0f75c3db0bf 309 Pfam PF01882 Protein of unknown function DUF58 52 144 3.0E-15 T 29-03-2018 IPR002881 Domain of unknown function DUF58 GBCGDNIH2_RS00720 1382694d76a0c84a03a5ced2819175e5 406 TIGRFAM TIGR01392 homoserO_Ac_trn: homoserine O-acetyltransferase 18 380 9.6E-134 T 29-03-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 GBCGDNIH2_RS00720 1382694d76a0c84a03a5ced2819175e5 406 SUPERFAMILY SSF53474 14 381 1.22E-100 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS00720 1382694d76a0c84a03a5ced2819175e5 406 PIRSF PIRSF000443 2 388 8.8E-132 T 29-03-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 GBCGDNIH2_RS00720 1382694d76a0c84a03a5ced2819175e5 406 Gene3D G3DSA:3.40.50.1820 27 387 6.1E-36 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS00720 1382694d76a0c84a03a5ced2819175e5 406 Pfam PF00561 alpha/beta hydrolase fold 47 368 1.7E-28 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 GBCGDNIH2_RS00720 1382694d76a0c84a03a5ced2819175e5 406 Hamap MF_00296 Homoserine O-acetyltransferase [metX]. 3 382 46.759 T 29-03-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 GBCGDNIH2_RS08995 a3b13c311781befcf0bb8000fbc4506a 471 Pfam PF03572 Peptidase family S41 206 372 4.2E-55 T 29-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 GBCGDNIH2_RS08995 a3b13c311781befcf0bb8000fbc4506a 471 Pfam PF13180 PDZ domain 108 188 1.1E-13 T 29-03-2018 IPR001478 PDZ domain GO:0005515 GBCGDNIH2_RS08995 a3b13c311781befcf0bb8000fbc4506a 471 SMART SM00228 108 179 6.7E-18 T 29-03-2018 IPR001478 PDZ domain GO:0005515 GBCGDNIH2_RS08995 a3b13c311781befcf0bb8000fbc4506a 471 Gene3D G3DSA:3.90.226.10 182 449 2.9E-70 T 29-03-2018 GBCGDNIH2_RS08995 a3b13c311781befcf0bb8000fbc4506a 471 SMART SM00245 181 373 6.2E-77 T 29-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 GBCGDNIH2_RS08995 a3b13c311781befcf0bb8000fbc4506a 471 Gene3D G3DSA:3.30.750.44 38 115 5.8E-18 T 29-03-2018 GBCGDNIH2_RS08995 a3b13c311781befcf0bb8000fbc4506a 471 SUPERFAMILY SSF52096 200 377 1.66E-83 T 29-03-2018 IPR029045 ClpP/crotonase-like domain GBCGDNIH2_RS08995 a3b13c311781befcf0bb8000fbc4506a 471 SUPERFAMILY SSF52096 49 126 1.66E-83 T 29-03-2018 IPR029045 ClpP/crotonase-like domain GBCGDNIH2_RS08995 a3b13c311781befcf0bb8000fbc4506a 471 SUPERFAMILY SSF50156 97 191 5.19E-22 T 29-03-2018 IPR001478 PDZ domain GO:0005515 GBCGDNIH2_RS08995 a3b13c311781befcf0bb8000fbc4506a 471 Gene3D G3DSA:2.30.42.10 116 181 2.1E-18 T 29-03-2018 GBCGDNIH2_RS08995 a3b13c311781befcf0bb8000fbc4506a 471 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 61 378 1.8E-100 T 29-03-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 GBCGDNIH2_RS05920 231e0240c53e9b6fefc891333e666980 192 Gene3D G3DSA:3.40.50.10420 1 190 3.3E-48 T 29-03-2018 GBCGDNIH2_RS05920 231e0240c53e9b6fefc891333e666980 192 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 12 180 1.2E-26 T 29-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase GBCGDNIH2_RS05920 231e0240c53e9b6fefc891333e666980 192 SUPERFAMILY SSF100950 12 189 8.65E-44 T 29-03-2018 GBCGDNIH2_RS05920 231e0240c53e9b6fefc891333e666980 192 PIRSF PIRSF006806 7 183 3.3E-29 T 29-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase GBCGDNIH2_RS05920 231e0240c53e9b6fefc891333e666980 192 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 12 180 1.9E-39 T 29-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase GBCGDNIH2_RS02935 8d348d72d7063b94b79c09219ba0731a 447 Hamap MF_01465 Protein translocase subunit SecY [secY]. 14 437 30.178 T 29-03-2018 IPR026593 Protein translocase subunit SecY GBCGDNIH2_RS02935 8d348d72d7063b94b79c09219ba0731a 447 ProSitePatterns PS00755 Protein secY signature 1. 80 99 - T 29-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 GBCGDNIH2_RS02935 8d348d72d7063b94b79c09219ba0731a 447 Pfam PF00344 SecY translocase 80 421 3.8E-120 T 29-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 GBCGDNIH2_RS02935 8d348d72d7063b94b79c09219ba0731a 447 PRINTS PR00303 Preprotein translocase SecY subunit signature 120 143 3.4E-97 T 29-03-2018 GBCGDNIH2_RS02935 8d348d72d7063b94b79c09219ba0731a 447 PRINTS PR00303 Preprotein translocase SecY subunit signature 79 99 3.4E-97 T 29-03-2018 GBCGDNIH2_RS02935 8d348d72d7063b94b79c09219ba0731a 447 PRINTS PR00303 Preprotein translocase SecY subunit signature 277 296 3.4E-97 T 29-03-2018 GBCGDNIH2_RS02935 8d348d72d7063b94b79c09219ba0731a 447 PRINTS PR00303 Preprotein translocase SecY subunit signature 27 45 3.4E-97 T 29-03-2018 GBCGDNIH2_RS02935 8d348d72d7063b94b79c09219ba0731a 447 PRINTS PR00303 Preprotein translocase SecY subunit signature 185 208 3.4E-97 T 29-03-2018 GBCGDNIH2_RS02935 8d348d72d7063b94b79c09219ba0731a 447 PRINTS PR00303 Preprotein translocase SecY subunit signature 319 341 3.4E-97 T 29-03-2018 GBCGDNIH2_RS02935 8d348d72d7063b94b79c09219ba0731a 447 PRINTS PR00303 Preprotein translocase SecY subunit signature 406 424 3.4E-97 T 29-03-2018 GBCGDNIH2_RS02935 8d348d72d7063b94b79c09219ba0731a 447 PRINTS PR00303 Preprotein translocase SecY subunit signature 159 184 3.4E-97 T 29-03-2018 GBCGDNIH2_RS02935 8d348d72d7063b94b79c09219ba0731a 447 PRINTS PR00303 Preprotein translocase SecY subunit signature 374 392 3.4E-97 T 29-03-2018 GBCGDNIH2_RS02935 8d348d72d7063b94b79c09219ba0731a 447 PIRSF PIRSF004557 2 445 6.3E-124 T 29-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 GBCGDNIH2_RS02935 8d348d72d7063b94b79c09219ba0731a 447 ProSitePatterns PS00756 Protein secY signature 2. 178 195 - T 29-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 GBCGDNIH2_RS02935 8d348d72d7063b94b79c09219ba0731a 447 Gene3D G3DSA:1.10.3370.10 12 443 4.2E-163 T 29-03-2018 GBCGDNIH2_RS02935 8d348d72d7063b94b79c09219ba0731a 447 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 24 432 4.3E-131 T 29-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 GBCGDNIH2_RS02935 8d348d72d7063b94b79c09219ba0731a 447 SUPERFAMILY SSF103491 15 428 1.15E-132 T 29-03-2018 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 GBCGDNIH2_RS10340 a444a103d02968f8c42d372f46d2d868 377 SUPERFAMILY SSF53448 33 283 3.94E-35 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS10340 a444a103d02968f8c42d372f46d2d868 377 Gene3D G3DSA:3.90.550.10 26 285 1.3E-36 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS10340 a444a103d02968f8c42d372f46d2d868 377 TIGRFAM TIGR03469 HpnB: hopene-associated glycosyltransferase HpnB 3 373 9.2E-142 T 29-03-2018 IPR017832 Glycosyl transferase, family 2, hopene-associated, HpnB GBCGDNIH2_RS10340 a444a103d02968f8c42d372f46d2d868 377 Pfam PF00535 Glycosyl transferase family 2 41 219 3.8E-23 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 GBCGDNIH2_RS04070 70ae7d5d4deba7d82eb12e525bf8aa6c 436 Gene3D G3DSA:1.20.1250.20 16 207 2.0E-17 T 29-03-2018 GBCGDNIH2_RS04070 70ae7d5d4deba7d82eb12e525bf8aa6c 436 Gene3D G3DSA:1.20.1250.20 212 428 1.7E-24 T 29-03-2018 GBCGDNIH2_RS04070 70ae7d5d4deba7d82eb12e525bf8aa6c 436 SUPERFAMILY SSF103473 15 422 1.96E-52 T 29-03-2018 IPR020846 Major facilitator superfamily domain GBCGDNIH2_RS04070 70ae7d5d4deba7d82eb12e525bf8aa6c 436 Pfam PF07690 Major Facilitator Superfamily 28 275 3.9E-24 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 GBCGDNIH2_RS04070 70ae7d5d4deba7d82eb12e525bf8aa6c 436 TIGRFAM TIGR04259 oxa_formateAnti: oxalate/formate antiporter 19 423 3.1E-185 T 29-03-2018 IPR026355 Oxalate/formate antiporter GO:0005215|GO:0006810|GO:0016021 GBCGDNIH2_RS05940 93106c12339a514bb5e60c0fb793edba 178 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 12 164 45.249 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 GBCGDNIH2_RS05940 93106c12339a514bb5e60c0fb793edba 178 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 14 164 1.5E-44 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 GBCGDNIH2_RS05940 93106c12339a514bb5e60c0fb793edba 178 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 14 161 1.0E-47 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 GBCGDNIH2_RS05940 93106c12339a514bb5e60c0fb793edba 178 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 149 161 6.2E-33 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 GBCGDNIH2_RS05940 93106c12339a514bb5e60c0fb793edba 178 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 72 88 6.2E-33 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 GBCGDNIH2_RS05940 93106c12339a514bb5e60c0fb793edba 178 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 94 110 6.2E-33 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 GBCGDNIH2_RS05940 93106c12339a514bb5e60c0fb793edba 178 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 118 137 6.2E-33 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 GBCGDNIH2_RS05940 93106c12339a514bb5e60c0fb793edba 178 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 15 28 6.2E-33 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 GBCGDNIH2_RS05940 93106c12339a514bb5e60c0fb793edba 178 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 124 158 - T 29-03-2018 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 GBCGDNIH2_RS05940 93106c12339a514bb5e60c0fb793edba 178 SUPERFAMILY SSF53098 13 165 2.4E-49 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 GBCGDNIH2_RS05940 93106c12339a514bb5e60c0fb793edba 178 Gene3D G3DSA:3.30.420.10 12 170 4.1E-45 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 GBCGDNIH2_RS08885 33f219d7f6a555e051d6a6350cad9f5d 248 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 179 190 1.8E-16 T 29-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial GBCGDNIH2_RS08885 33f219d7f6a555e051d6a6350cad9f5d 248 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 168 178 1.8E-16 T 29-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial GBCGDNIH2_RS08885 33f219d7f6a555e051d6a6350cad9f5d 248 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 110 127 1.8E-16 T 29-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial GBCGDNIH2_RS08885 33f219d7f6a555e051d6a6350cad9f5d 248 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 191 206 1.8E-16 T 29-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial GBCGDNIH2_RS08885 33f219d7f6a555e051d6a6350cad9f5d 248 Pfam PF01478 Type IV leader peptidase family 102 209 2.6E-15 T 29-03-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 GBCGDNIH2_RS08885 33f219d7f6a555e051d6a6350cad9f5d 248 Gene3D G3DSA:2.20.28.20 31 50 0.077 T 29-03-2018 GBCGDNIH2_RS08885 33f219d7f6a555e051d6a6350cad9f5d 248 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 9 87 5.2E-25 T 29-03-2018 IPR010627 Peptidase A24A, N-terminal GBCGDNIH2_RS06090 9b0aa3a940b914aba48e89ccbe626981 272 SUPERFAMILY SSF101386 10 107 9.16E-24 T 29-03-2018 GBCGDNIH2_RS06090 9b0aa3a940b914aba48e89ccbe626981 272 TIGRFAM TIGR00444 mazG: MazG family protein 16 263 1.2E-84 T 29-03-2018 IPR011551 NTP pyrophosphohydrolase MazG GBCGDNIH2_RS06090 9b0aa3a940b914aba48e89ccbe626981 272 Gene3D G3DSA:1.10.287.1080 145 269 5.5E-29 T 29-03-2018 GBCGDNIH2_RS06090 9b0aa3a940b914aba48e89ccbe626981 272 Gene3D G3DSA:1.10.287.1080 9 130 4.0E-37 T 29-03-2018 GBCGDNIH2_RS06090 9b0aa3a940b914aba48e89ccbe626981 272 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 33 106 1.0E-27 T 29-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core GBCGDNIH2_RS06090 9b0aa3a940b914aba48e89ccbe626981 272 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 172 234 4.3E-10 T 29-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core GBCGDNIH2_RS06090 9b0aa3a940b914aba48e89ccbe626981 272 SUPERFAMILY SSF101386 144 242 2.06E-23 T 29-03-2018 GBCGDNIH2_RS07345 528e9eef721be47c615a5a58d2a04a94 227 SUPERFAMILY SSF117987 22 83 2.25E-5 T 29-03-2018 GBCGDNIH2_RS07345 528e9eef721be47c615a5a58d2a04a94 227 SMART SM01101 3 226 2.0E-79 T 29-03-2018 IPR010179 CRISPR-associated protein Cse3 GBCGDNIH2_RS07345 528e9eef721be47c615a5a58d2a04a94 227 Gene3D G3DSA:3.30.70.1200 1 100 1.0E-14 T 29-03-2018 GBCGDNIH2_RS07345 528e9eef721be47c615a5a58d2a04a94 227 Gene3D G3DSA:3.30.70.1210 101 226 4.5E-21 T 29-03-2018 GBCGDNIH2_RS07345 528e9eef721be47c615a5a58d2a04a94 227 TIGRFAM TIGR01907 casE_Cse3: CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI 39 226 3.4E-35 T 29-03-2018 IPR010179 CRISPR-associated protein Cse3 GBCGDNIH2_RS07345 528e9eef721be47c615a5a58d2a04a94 227 SUPERFAMILY SSF117987 94 226 1.12E-22 T 29-03-2018 GBCGDNIH2_RS07345 528e9eef721be47c615a5a58d2a04a94 227 Pfam PF08798 CRISPR associated protein 4 226 1.5E-45 T 29-03-2018 IPR010179 CRISPR-associated protein Cse3 GBCGDNIH2_RS03625 eb594649667932fb19be5488a1b645c7 284 Gene3D G3DSA:1.10.1160.10 243 277 0.0011 T 29-03-2018 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 GBCGDNIH2_RS03625 eb594649667932fb19be5488a1b645c7 284 PRINTS PR00987 Glutamyl-tRNA synthetase signature 206 214 5.0E-6 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 GBCGDNIH2_RS03625 eb594649667932fb19be5488a1b645c7 284 PRINTS PR00987 Glutamyl-tRNA synthetase signature 6 18 5.0E-6 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 GBCGDNIH2_RS03625 eb594649667932fb19be5488a1b645c7 284 PRINTS PR00987 Glutamyl-tRNA synthetase signature 190 200 5.0E-6 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 GBCGDNIH2_RS03625 eb594649667932fb19be5488a1b645c7 284 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 3 276 8.6E-43 T 29-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 GBCGDNIH2_RS03625 eb594649667932fb19be5488a1b645c7 284 SUPERFAMILY SSF52374 3 274 6.44E-75 T 29-03-2018 GBCGDNIH2_RS03625 eb594649667932fb19be5488a1b645c7 284 Gene3D G3DSA:3.40.50.620 115 241 2.9E-31 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GBCGDNIH2_RS03625 eb594649667932fb19be5488a1b645c7 284 Gene3D G3DSA:3.40.50.620 3 114 4.0E-30 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GBCGDNIH2_RS03625 eb594649667932fb19be5488a1b645c7 284 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 9 20 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 GBCGDNIH2_RS10275 11d76eaaf4574aafd92e9bc2918c356e 933 Gene3D G3DSA:1.20.1060.10 506 656 1.3E-47 T 29-03-2018 GBCGDNIH2_RS10275 11d76eaaf4574aafd92e9bc2918c356e 933 PRINTS PR00868 DNA-polymerase family A (pol I) signature 880 893 1.0E-73 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GBCGDNIH2_RS10275 11d76eaaf4574aafd92e9bc2918c356e 933 PRINTS PR00868 DNA-polymerase family A (pol I) signature 850 866 1.0E-73 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GBCGDNIH2_RS10275 11d76eaaf4574aafd92e9bc2918c356e 933 PRINTS PR00868 DNA-polymerase family A (pol I) signature 683 698 1.0E-73 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GBCGDNIH2_RS10275 11d76eaaf4574aafd92e9bc2918c356e 933 PRINTS PR00868 DNA-polymerase family A (pol I) signature 759 784 1.0E-73 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GBCGDNIH2_RS10275 11d76eaaf4574aafd92e9bc2918c356e 933 PRINTS PR00868 DNA-polymerase family A (pol I) signature 796 807 1.0E-73 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GBCGDNIH2_RS10275 11d76eaaf4574aafd92e9bc2918c356e 933 PRINTS PR00868 DNA-polymerase family A (pol I) signature 660 682 1.0E-73 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GBCGDNIH2_RS10275 11d76eaaf4574aafd92e9bc2918c356e 933 PRINTS PR00868 DNA-polymerase family A (pol I) signature 705 728 1.0E-73 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GBCGDNIH2_RS10275 11d76eaaf4574aafd92e9bc2918c356e 933 PRINTS PR00868 DNA-polymerase family A (pol I) signature 735 748 1.0E-73 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GBCGDNIH2_RS10275 11d76eaaf4574aafd92e9bc2918c356e 933 PRINTS PR00868 DNA-polymerase family A (pol I) signature 818 829 1.0E-73 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GBCGDNIH2_RS10275 11d76eaaf4574aafd92e9bc2918c356e 933 Gene3D G3DSA:3.30.420.10 325 505 3.6E-33 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 GBCGDNIH2_RS10275 11d76eaaf4574aafd92e9bc2918c356e 933 Gene3D G3DSA:1.10.150.20 188 252 3.6E-29 T 29-03-2018 GBCGDNIH2_RS10275 11d76eaaf4574aafd92e9bc2918c356e 933 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 179 274 4.0E-33 T 29-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 GBCGDNIH2_RS10275 11d76eaaf4574aafd92e9bc2918c356e 933 SUPERFAMILY SSF88723 15 178 5.61E-51 T 29-03-2018 IPR029060 PIN domain-like GBCGDNIH2_RS10275 11d76eaaf4574aafd92e9bc2918c356e 933 ProSitePatterns PS00447 DNA polymerase family A signature. 759 778 - T 29-03-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GBCGDNIH2_RS10275 11d76eaaf4574aafd92e9bc2918c356e 933 SMART SM00482 691 897 3.7E-113 T 29-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GBCGDNIH2_RS10275 11d76eaaf4574aafd92e9bc2918c356e 933 TIGRFAM TIGR00593 pola: DNA polymerase I 17 933 4.9E-282 T 29-03-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GBCGDNIH2_RS10275 11d76eaaf4574aafd92e9bc2918c356e 933 SUPERFAMILY SSF53098 330 522 2.01E-50 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 GBCGDNIH2_RS10275 11d76eaaf4574aafd92e9bc2918c356e 933 Gene3D G3DSA:3.30.70.370 659 757 2.8E-16 T 29-03-2018 GBCGDNIH2_RS10275 11d76eaaf4574aafd92e9bc2918c356e 933 Gene3D G3DSA:3.30.70.370 759 933 3.5E-50 T 29-03-2018 GBCGDNIH2_RS10275 11d76eaaf4574aafd92e9bc2918c356e 933 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 16 178 4.0E-54 T 29-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 GBCGDNIH2_RS10275 11d76eaaf4574aafd92e9bc2918c356e 933 Gene3D G3DSA:3.40.50.1010 15 187 9.8E-67 T 29-03-2018 IPR029060 PIN domain-like GBCGDNIH2_RS10275 11d76eaaf4574aafd92e9bc2918c356e 933 Pfam PF00476 DNA polymerase family A 554 931 2.3E-143 T 29-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GBCGDNIH2_RS10275 11d76eaaf4574aafd92e9bc2918c356e 933 SUPERFAMILY SSF47807 179 293 3.74E-31 T 29-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 GBCGDNIH2_RS10275 11d76eaaf4574aafd92e9bc2918c356e 933 SMART SM00279 181 216 1.6E-16 T 29-03-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 GBCGDNIH2_RS10275 11d76eaaf4574aafd92e9bc2918c356e 933 SMART SM00474 332 521 1.3E-31 T 29-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 GBCGDNIH2_RS10275 11d76eaaf4574aafd92e9bc2918c356e 933 SMART SM00475 15 270 1.6E-119 T 29-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 GBCGDNIH2_RS10275 11d76eaaf4574aafd92e9bc2918c356e 933 Pfam PF01612 3'-5' exonuclease 332 520 1.4E-31 T 29-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 GBCGDNIH2_RS10275 11d76eaaf4574aafd92e9bc2918c356e 933 SUPERFAMILY SSF56672 528 933 5.45E-147 T 29-03-2018 GBCGDNIH2_RS11095 d93f5f3ee9b1d367eff6466631378e24 673 Pfam PF04632 Fusaric acid resistance protein family 29 665 4.0E-164 T 29-03-2018 IPR006726 Para-hydroxybenzoic acid efflux pump subunit AaeB/fusaric acid resistance protein GO:0005886|GO:0006810 GBCGDNIH2_RS11130 a52faa40354f4cfed12b7e413902bd43 317 SUPERFAMILY SSF52540 37 283 8.4E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS11130 a52faa40354f4cfed12b7e413902bd43 317 PRINTS PR00820 CbxX/CfqX protein signature 55 69 3.2E-32 T 29-03-2018 IPR000470 CbxX/CfqX, monofunctional GO:0005524 GBCGDNIH2_RS11130 a52faa40354f4cfed12b7e413902bd43 317 PRINTS PR00820 CbxX/CfqX protein signature 265 276 3.2E-32 T 29-03-2018 IPR000470 CbxX/CfqX, monofunctional GO:0005524 GBCGDNIH2_RS11130 a52faa40354f4cfed12b7e413902bd43 317 PRINTS PR00820 CbxX/CfqX protein signature 289 303 3.2E-32 T 29-03-2018 IPR000470 CbxX/CfqX, monofunctional GO:0005524 GBCGDNIH2_RS11130 a52faa40354f4cfed12b7e413902bd43 317 PRINTS PR00820 CbxX/CfqX protein signature 37 51 3.2E-32 T 29-03-2018 IPR000470 CbxX/CfqX, monofunctional GO:0005524 GBCGDNIH2_RS11130 a52faa40354f4cfed12b7e413902bd43 317 PRINTS PR00820 CbxX/CfqX protein signature 96 111 3.2E-32 T 29-03-2018 IPR000470 CbxX/CfqX, monofunctional GO:0005524 GBCGDNIH2_RS11130 a52faa40354f4cfed12b7e413902bd43 317 PRINTS PR00820 CbxX/CfqX protein signature 250 261 3.2E-32 T 29-03-2018 IPR000470 CbxX/CfqX, monofunctional GO:0005524 GBCGDNIH2_RS11130 a52faa40354f4cfed12b7e413902bd43 317 PRINTS PR00819 CbxX/CfqX superfamily signature 134 153 1.7E-52 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 GBCGDNIH2_RS11130 a52faa40354f4cfed12b7e413902bd43 317 PRINTS PR00819 CbxX/CfqX superfamily signature 163 175 1.7E-52 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 GBCGDNIH2_RS11130 a52faa40354f4cfed12b7e413902bd43 317 PRINTS PR00819 CbxX/CfqX superfamily signature 258 270 1.7E-52 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 GBCGDNIH2_RS11130 a52faa40354f4cfed12b7e413902bd43 317 PRINTS PR00819 CbxX/CfqX superfamily signature 184 201 1.7E-52 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 GBCGDNIH2_RS11130 a52faa40354f4cfed12b7e413902bd43 317 PRINTS PR00819 CbxX/CfqX superfamily signature 82 97 1.7E-52 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 GBCGDNIH2_RS11130 a52faa40354f4cfed12b7e413902bd43 317 PRINTS PR00819 CbxX/CfqX superfamily signature 201 220 1.7E-52 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 GBCGDNIH2_RS11130 a52faa40354f4cfed12b7e413902bd43 317 PRINTS PR00819 CbxX/CfqX superfamily signature 42 56 1.7E-52 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 GBCGDNIH2_RS11130 a52faa40354f4cfed12b7e413902bd43 317 PRINTS PR00819 CbxX/CfqX superfamily signature 120 134 1.7E-52 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 GBCGDNIH2_RS11130 a52faa40354f4cfed12b7e413902bd43 317 SMART SM00382 79 216 4.8E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS11130 a52faa40354f4cfed12b7e413902bd43 317 Gene3D G3DSA:3.40.50.300 24 213 1.6E-27 T 29-03-2018 GBCGDNIH2_RS11130 a52faa40354f4cfed12b7e413902bd43 317 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 83 213 6.2E-14 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 GBCGDNIH2_RS01030 3b7276ea021a26e679a3949fb14dbdf2 185 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 36 183 3.2E-29 T 29-03-2018 IPR019587 Polyketide cyclase/dehydrase GBCGDNIH2_RS01030 3b7276ea021a26e679a3949fb14dbdf2 185 SUPERFAMILY SSF55961 36 182 6.75E-25 T 29-03-2018 GBCGDNIH2_RS01030 3b7276ea021a26e679a3949fb14dbdf2 185 Gene3D G3DSA:3.30.530.20 26 182 3.4E-26 T 29-03-2018 IPR023393 START-like domain GBCGDNIH2_RS05910 707ef9bf0927db0f00eb63819232ff49 121 SUPERFAMILY SSF102829 3 77 2.88E-19 T 29-03-2018 IPR007838 Cell division protein ZapA-like GBCGDNIH2_RS05910 707ef9bf0927db0f00eb63819232ff49 121 Gene3D G3DSA:1.20.120.160 7 121 0.0011 T 29-03-2018 GBCGDNIH2_RS05910 707ef9bf0927db0f00eb63819232ff49 121 Pfam PF05164 Cell division protein ZapA 4 110 6.0E-22 T 29-03-2018 IPR007838 Cell division protein ZapA-like GBCGDNIH2_RS12280 52bbba1a08dbca0ad84a6d27acda094b 216 Gene3D G3DSA:3.40.50.2020 10 214 2.0E-61 T 29-03-2018 GBCGDNIH2_RS12280 52bbba1a08dbca0ad84a6d27acda094b 216 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 11 216 6.4E-78 T 29-03-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 GBCGDNIH2_RS12280 52bbba1a08dbca0ad84a6d27acda094b 216 SUPERFAMILY SSF53271 12 214 9.96E-67 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like GBCGDNIH2_RS12280 52bbba1a08dbca0ad84a6d27acda094b 216 Pfam PF14681 Uracil phosphoribosyltransferase 13 215 1.2E-72 T 29-03-2018 GBCGDNIH2_RS12280 52bbba1a08dbca0ad84a6d27acda094b 216 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 10 216 42.808 T 29-03-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 GBCGDNIH2_RS04300 d3e2d12b53f3c7bd2012493a27226d18 214 Gene3D G3DSA:2.30.110.10 36 198 1.4E-24 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 GBCGDNIH2_RS04300 d3e2d12b53f3c7bd2012493a27226d18 214 SUPERFAMILY SSF50475 41 145 2.27E-19 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 GBCGDNIH2_RS04300 d3e2d12b53f3c7bd2012493a27226d18 214 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 46 138 1.1E-15 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 GBCGDNIH2_RS05300 6de8defbf213f3ce31ee750e922918d2 503 Pfam PF01078 Magnesium chelatase, subunit ChlI 198 402 4.9E-90 T 29-03-2018 IPR000523 Magnesium chelatase ChlI domain GBCGDNIH2_RS05300 6de8defbf213f3ce31ee750e922918d2 503 Pfam PF13541 Subunit ChlI of Mg-chelatase 30 148 1.1E-38 T 29-03-2018 GBCGDNIH2_RS05300 6de8defbf213f3ce31ee750e922918d2 503 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 16 497 3.8E-148 T 29-03-2018 IPR004482 Mg chelatase-related protein GBCGDNIH2_RS05300 6de8defbf213f3ce31ee750e922918d2 503 SMART SM00382 218 383 1.3E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS05300 6de8defbf213f3ce31ee750e922918d2 503 SUPERFAMILY SSF54211 13 178 1.71E-28 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold GBCGDNIH2_RS05300 6de8defbf213f3ce31ee750e922918d2 503 Gene3D G3DSA:3.30.230.10 2 196 1.6E-31 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup GBCGDNIH2_RS05300 6de8defbf213f3ce31ee750e922918d2 503 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 410 497 2.6E-19 T 29-03-2018 IPR025158 Mg chelatase-related protein, C-terminal domain GBCGDNIH2_RS05300 6de8defbf213f3ce31ee750e922918d2 503 SUPERFAMILY SSF52540 198 498 1.58E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS05300 6de8defbf213f3ce31ee750e922918d2 503 Gene3D G3DSA:3.40.50.300 197 395 9.6E-23 T 29-03-2018 GBCGDNIH2_RS05300 6de8defbf213f3ce31ee750e922918d2 503 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 217 232 5.7E-6 T 29-03-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 GBCGDNIH2_RS05300 6de8defbf213f3ce31ee750e922918d2 503 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 297 311 5.7E-6 T 29-03-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 GBCGDNIH2_RS05300 6de8defbf213f3ce31ee750e922918d2 503 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 325 338 5.7E-6 T 29-03-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 GBCGDNIH2_RS05300 6de8defbf213f3ce31ee750e922918d2 503 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 349 361 5.7E-6 T 29-03-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 GBCGDNIH2_RS11890 b9eb9f93a6103a2729f8283fa5e38826 475 SUPERFAMILY SSF52540 38 243 9.97E-11 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS11890 b9eb9f93a6103a2729f8283fa5e38826 475 Gene3D G3DSA:3.40.50.300 37 164 3.1E-6 T 29-03-2018 GBCGDNIH2_RS10925 e678cc66dd5943e4c252fd3ae0224ae7 684 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 3 682 1.2E-148 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 GBCGDNIH2_RS10925 e678cc66dd5943e4c252fd3ae0224ae7 684 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 4 535 2.6E-178 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 GBCGDNIH2_RS10925 e678cc66dd5943e4c252fd3ae0224ae7 684 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 386 405 1.7E-25 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 GBCGDNIH2_RS10925 e678cc66dd5943e4c252fd3ae0224ae7 684 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 5 18 1.7E-25 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 GBCGDNIH2_RS10925 e678cc66dd5943e4c252fd3ae0224ae7 684 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 46 58 1.7E-25 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 GBCGDNIH2_RS10925 e678cc66dd5943e4c252fd3ae0224ae7 684 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 310 326 1.7E-25 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 GBCGDNIH2_RS10925 e678cc66dd5943e4c252fd3ae0224ae7 684 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 237 252 1.7E-25 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 GBCGDNIH2_RS10925 e678cc66dd5943e4c252fd3ae0224ae7 684 Pfam PF05746 DALR anticodon binding domain 571 674 1.4E-9 T 29-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 GBCGDNIH2_RS10925 e678cc66dd5943e4c252fd3ae0224ae7 684 SUPERFAMILY SSF109604 334 484 2.67E-16 T 29-03-2018 GBCGDNIH2_RS10925 e678cc66dd5943e4c252fd3ae0224ae7 684 Gene3D G3DSA:1.10.730.10 565 678 8.0E-16 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 GBCGDNIH2_RS10925 e678cc66dd5943e4c252fd3ae0224ae7 684 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 1 682 21.5 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 GBCGDNIH2_RS04140 d2cca03872aa66e836d0a5bf4ab4bd93 378 Gene3D G3DSA:3.40.50.450 105 254 1.8E-34 T 29-03-2018 GBCGDNIH2_RS04140 d2cca03872aa66e836d0a5bf4ab4bd93 378 Pfam PF02481 DNA recombination-mediator protein A 65 268 4.7E-69 T 29-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 GBCGDNIH2_RS04140 d2cca03872aa66e836d0a5bf4ab4bd93 378 SUPERFAMILY SSF102405 73 278 2.56E-40 T 29-03-2018 GBCGDNIH2_RS04140 d2cca03872aa66e836d0a5bf4ab4bd93 378 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 62 278 5.5E-67 T 29-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 GBCGDNIH2_RS04140 d2cca03872aa66e836d0a5bf4ab4bd93 378 Gene3D G3DSA:1.10.10.10 275 374 6.7E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS03020 9ef3db1965ed885e574d24a425e7b483 469 Gene3D G3DSA:3.40.120.10 263 370 3.8E-26 T 29-03-2018 GBCGDNIH2_RS03020 9ef3db1965ed885e574d24a425e7b483 469 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 173 255 2.1E-20 T 29-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GBCGDNIH2_RS03020 9ef3db1965ed885e574d24a425e7b483 469 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 375 452 9.4E-13 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GBCGDNIH2_RS03020 9ef3db1965ed885e574d24a425e7b483 469 SUPERFAMILY SSF55957 369 454 1.1E-21 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GBCGDNIH2_RS03020 9ef3db1965ed885e574d24a425e7b483 469 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 12 121 3.7E-32 T 29-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GBCGDNIH2_RS03020 9ef3db1965ed885e574d24a425e7b483 469 Gene3D G3DSA:3.40.120.10 4 161 4.6E-35 T 29-03-2018 GBCGDNIH2_RS03020 9ef3db1965ed885e574d24a425e7b483 469 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 235 250 7.2E-22 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GBCGDNIH2_RS03020 9ef3db1965ed885e574d24a425e7b483 469 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 172 191 7.2E-22 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GBCGDNIH2_RS03020 9ef3db1965ed885e574d24a425e7b483 469 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 99 113 7.2E-22 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GBCGDNIH2_RS03020 9ef3db1965ed885e574d24a425e7b483 469 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 206 219 7.2E-22 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GBCGDNIH2_RS03020 9ef3db1965ed885e574d24a425e7b483 469 SUPERFAMILY SSF53738 5 132 2.08E-37 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GBCGDNIH2_RS03020 9ef3db1965ed885e574d24a425e7b483 469 SUPERFAMILY SSF53738 260 366 3.57E-34 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GBCGDNIH2_RS03020 9ef3db1965ed885e574d24a425e7b483 469 Gene3D G3DSA:3.30.310.50 371 456 2.5E-16 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GBCGDNIH2_RS03020 9ef3db1965ed885e574d24a425e7b483 469 SUPERFAMILY SSF53738 157 256 1.71E-25 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GBCGDNIH2_RS03020 9ef3db1965ed885e574d24a425e7b483 469 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 100 109 - T 29-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GBCGDNIH2_RS03020 9ef3db1965ed885e574d24a425e7b483 469 Gene3D G3DSA:3.40.120.10 162 262 1.1E-29 T 29-03-2018 GBCGDNIH2_RS03020 9ef3db1965ed885e574d24a425e7b483 469 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 260 368 5.8E-23 T 29-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GBCGDNIH2_RS03045 cd331a2592a2c085bb762a8288f92c5e 73 Gene3D G3DSA:3.30.1190.10 31 69 1.5E-9 T 29-03-2018 GBCGDNIH2_RS03045 cd331a2592a2c085bb762a8288f92c5e 73 Gene3D G3DSA:1.10.10.60 1 30 5.6E-9 T 29-03-2018 GBCGDNIH2_RS03045 cd331a2592a2c085bb762a8288f92c5e 73 Pfam PF01381 Helix-turn-helix 12 63 1.1E-13 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 GBCGDNIH2_RS03045 cd331a2592a2c085bb762a8288f92c5e 73 SMART SM00530 10 65 9.1E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 GBCGDNIH2_RS03045 cd331a2592a2c085bb762a8288f92c5e 73 SUPERFAMILY SSF47413 2 67 2.57E-16 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GBCGDNIH2_RS05260 8502a972f265d801241de5f923a0e5ae 128 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 4 107 31.712 T 29-03-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 GBCGDNIH2_RS05260 8502a972f265d801241de5f923a0e5ae 128 SUPERFAMILY SSF141734 5 117 1.16E-49 T 29-03-2018 GBCGDNIH2_RS05260 8502a972f265d801241de5f923a0e5ae 128 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 53 106 3.0E-18 T 29-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 GBCGDNIH2_RS05260 8502a972f265d801241de5f923a0e5ae 128 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 30 103 2.1E-35 T 29-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 GBCGDNIH2_RS08780 5080bac695a3dea5108d038823652a83 89 SUPERFAMILY SSF82697 10 87 4.71E-27 T 29-03-2018 GBCGDNIH2_RS08780 5080bac695a3dea5108d038823652a83 89 Gene3D G3DSA:3.30.1280.10 9 88 1.7E-30 T 29-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 GBCGDNIH2_RS08780 5080bac695a3dea5108d038823652a83 89 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 10 87 20.943 T 29-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 GBCGDNIH2_RS08780 5080bac695a3dea5108d038823652a83 89 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 11 87 1.7E-30 T 29-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 GBCGDNIH2_RS08780 5080bac695a3dea5108d038823652a83 89 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 18 86 4.0E-20 T 29-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 GBCGDNIH2_RS08780 5080bac695a3dea5108d038823652a83 89 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 11 88 4.1E-26 T 29-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 GBCGDNIH2_RS03520 02e5edba67a7bce1345ba54cdec20a02 280 Gene3D G3DSA:3.30.70.660 126 263 2.7E-38 T 29-03-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 GBCGDNIH2_RS03520 02e5edba67a7bce1345ba54cdec20a02 280 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 11 264 32.883 T 29-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 GBCGDNIH2_RS03520 02e5edba67a7bce1345ba54cdec20a02 280 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 14 258 3.6E-46 T 29-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 GBCGDNIH2_RS03520 02e5edba67a7bce1345ba54cdec20a02 280 SUPERFAMILY SSF55120 10 274 8.63E-79 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 GBCGDNIH2_RS03520 02e5edba67a7bce1345ba54cdec20a02 280 Pfam PF01416 tRNA pseudouridine synthase 163 265 9.0E-31 T 29-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 GBCGDNIH2_RS03520 02e5edba67a7bce1345ba54cdec20a02 280 Gene3D G3DSA:3.30.70.580 9 125 4.2E-24 T 29-03-2018 GBCGDNIH2_RS03520 02e5edba67a7bce1345ba54cdec20a02 280 PIRSF PIRSF001430 10 278 1.1E-67 T 29-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 GBCGDNIH2_RS11610 7ad6525126911d4112596d93d83124cc 239 Pfam PF00072 Response regulator receiver domain 14 124 1.8E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GBCGDNIH2_RS11610 7ad6525126911d4112596d93d83124cc 239 Gene3D G3DSA:3.40.50.2300 7 133 5.8E-41 T 29-03-2018 GBCGDNIH2_RS11610 7ad6525126911d4112596d93d83124cc 239 Pfam PF00486 Transcriptional regulatory protein, C terminal 164 235 6.3E-20 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 GBCGDNIH2_RS11610 7ad6525126911d4112596d93d83124cc 239 SUPERFAMILY SSF46894 144 235 3.12E-20 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 GBCGDNIH2_RS11610 7ad6525126911d4112596d93d83124cc 239 SMART SM00448 12 123 3.4E-39 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GBCGDNIH2_RS11610 7ad6525126911d4112596d93d83124cc 239 Gene3D G3DSA:1.10.10.10 134 238 1.6E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS11610 7ad6525126911d4112596d93d83124cc 239 SMART SM00862 161 235 7.4E-20 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 GBCGDNIH2_RS11610 7ad6525126911d4112596d93d83124cc 239 SUPERFAMILY SSF52172 12 133 1.99E-40 T 29-03-2018 IPR011006 CheY-like superfamily GBCGDNIH2_RS07270 97ad7d13f0cb007a295deb5aa78ba576 732 Pfam PF00593 TonB dependent receptor 266 730 1.4E-34 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 GBCGDNIH2_RS07270 97ad7d13f0cb007a295deb5aa78ba576 732 Gene3D G3DSA:2.170.130.10 45 175 6.8E-9 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 GBCGDNIH2_RS07270 97ad7d13f0cb007a295deb5aa78ba576 732 Gene3D G3DSA:2.40.170.20 176 732 1.1E-55 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 GBCGDNIH2_RS07270 97ad7d13f0cb007a295deb5aa78ba576 732 SUPERFAMILY SSF56935 51 732 1.36E-70 T 29-03-2018 GBCGDNIH2_RS09695 64ca22d93ed9b4dcb567ebae5974aeb0 176 PIRSF PIRSF006443 1 168 4.8E-61 T 29-03-2018 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 GBCGDNIH2_RS09695 64ca22d93ed9b4dcb567ebae5974aeb0 176 TIGRFAM TIGR02667 moaB_proteo: molybdenum cofactor biosynthesis protein B 10 171 8.9E-76 T 29-03-2018 IPR013484 Molybdenum cofactor biosynthesis protein B, proteobacteria GO:0006777 GBCGDNIH2_RS09695 64ca22d93ed9b4dcb567ebae5974aeb0 176 SMART SM00852 16 160 1.4E-32 T 29-03-2018 IPR001453 MoaB/Mog domain GBCGDNIH2_RS09695 64ca22d93ed9b4dcb567ebae5974aeb0 176 Gene3D G3DSA:3.40.980.10 3 172 2.5E-36 T 29-03-2018 IPR001453 MoaB/Mog domain GBCGDNIH2_RS09695 64ca22d93ed9b4dcb567ebae5974aeb0 176 SUPERFAMILY SSF53218 7 172 1.31E-47 T 29-03-2018 IPR001453 MoaB/Mog domain GBCGDNIH2_RS09695 64ca22d93ed9b4dcb567ebae5974aeb0 176 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 14 153 1.3E-37 T 29-03-2018 IPR001453 MoaB/Mog domain GBCGDNIH2_RS09695 64ca22d93ed9b4dcb567ebae5974aeb0 176 Pfam PF00994 Probable molybdopterin binding domain 16 154 1.2E-33 T 29-03-2018 IPR001453 MoaB/Mog domain GBCGDNIH2_RS04505 5a3425df449259ca9fd91e1264cd628c 629 SMART SM00341 556 627 5.6E-9 T 29-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 GBCGDNIH2_RS04505 5a3425df449259ca9fd91e1264cd628c 629 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 22 626 5.6E-215 T 29-03-2018 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 GBCGDNIH2_RS04505 5a3425df449259ca9fd91e1264cd628c 629 SUPERFAMILY SSF52540 72 355 2.19E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS04505 5a3425df449259ca9fd91e1264cd628c 629 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 22 480 5.8E-139 T 29-03-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 GBCGDNIH2_RS04505 5a3425df449259ca9fd91e1264cd628c 629 SUPERFAMILY SSF47819 555 628 9.16E-22 T 29-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 GBCGDNIH2_RS04505 5a3425df449259ca9fd91e1264cd628c 629 Pfam PF00570 HRDC domain 563 625 1.2E-21 T 29-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 GBCGDNIH2_RS04505 5a3425df449259ca9fd91e1264cd628c 629 Pfam PF00270 DEAD/DEAH box helicase 36 194 3.7E-20 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 GBCGDNIH2_RS04505 5a3425df449259ca9fd91e1264cd628c 629 Pfam PF09382 RQC domain 413 535 2.6E-39 T 29-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 GBCGDNIH2_RS04505 5a3425df449259ca9fd91e1264cd628c 629 Gene3D G3DSA:3.40.50.300 11 214 9.9E-35 T 29-03-2018 GBCGDNIH2_RS04505 5a3425df449259ca9fd91e1264cd628c 629 Gene3D G3DSA:1.10.150.80 535 629 9.7E-23 T 29-03-2018 GBCGDNIH2_RS04505 5a3425df449259ca9fd91e1264cd628c 629 SUPERFAMILY SSF46785 410 539 1.35E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS04505 5a3425df449259ca9fd91e1264cd628c 629 SMART SM00490 256 337 1.8E-29 T 29-03-2018 IPR001650 Helicase, C-terminal GBCGDNIH2_RS04505 5a3425df449259ca9fd91e1264cd628c 629 Pfam PF16124 RecQ zinc-binding 349 411 3.3E-13 T 29-03-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain GBCGDNIH2_RS04505 5a3425df449259ca9fd91e1264cd628c 629 Gene3D G3DSA:3.40.50.300 219 355 5.9E-33 T 29-03-2018 GBCGDNIH2_RS04505 5a3425df449259ca9fd91e1264cd628c 629 SMART SM00956 418 532 5.6E-44 T 29-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 GBCGDNIH2_RS04505 5a3425df449259ca9fd91e1264cd628c 629 SMART SM00487 29 222 4.3E-27 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain GBCGDNIH2_RS04505 5a3425df449259ca9fd91e1264cd628c 629 Pfam PF00271 Helicase conserved C-terminal domain 233 336 2.8E-20 T 29-03-2018 IPR001650 Helicase, C-terminal GBCGDNIH2_RS04505 5a3425df449259ca9fd91e1264cd628c 629 Gene3D G3DSA:1.10.10.10 356 534 4.3E-38 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS10290 6b505240ba4d0b05a33b72c4c652382a 314 Gene3D G3DSA:3.40.190.10 93 181 1.6E-23 T 29-03-2018 GBCGDNIH2_RS10290 6b505240ba4d0b05a33b72c4c652382a 314 Gene3D G3DSA:1.10.10.10 1 88 5.0E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS10290 6b505240ba4d0b05a33b72c4c652382a 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 8.5E-21 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS10290 6b505240ba4d0b05a33b72c4c652382a 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 8.8E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS10290 6b505240ba4d0b05a33b72c4c652382a 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 8.8E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS10290 6b505240ba4d0b05a33b72c4c652382a 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 8.8E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS10290 6b505240ba4d0b05a33b72c4c652382a 314 Pfam PF03466 LysR substrate binding domain 92 288 1.2E-37 T 29-03-2018 IPR005119 LysR, substrate-binding GBCGDNIH2_RS10290 6b505240ba4d0b05a33b72c4c652382a 314 SUPERFAMILY SSF53850 94 303 1.67E-36 T 29-03-2018 GBCGDNIH2_RS10290 6b505240ba4d0b05a33b72c4c652382a 314 SUPERFAMILY SSF46785 6 116 4.74E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS10290 6b505240ba4d0b05a33b72c4c652382a 314 Gene3D G3DSA:3.40.190.10 182 276 3.0E-19 T 29-03-2018 GBCGDNIH2_RS08175 bd364be85c6885703a86bc0612cac621 435 Gene3D G3DSA:2.40.50.100 99 171 1.8E-19 T 29-03-2018 GBCGDNIH2_RS08175 bd364be85c6885703a86bc0612cac621 435 Gene3D G3DSA:2.40.50.100 199 420 0.0048 T 29-03-2018 GBCGDNIH2_RS08175 bd364be85c6885703a86bc0612cac621 435 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 81 419 1.5E-78 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 GBCGDNIH2_RS08175 bd364be85c6885703a86bc0612cac621 435 SUPERFAMILY SSF111369 90 343 1.14E-60 T 29-03-2018 GBCGDNIH2_RS08175 bd364be85c6885703a86bc0612cac621 435 Pfam PF13533 Biotin-lipoyl like 101 146 1.8E-13 T 29-03-2018 GBCGDNIH2_RS05330 857ae6fcdc0eaa0b12f59099579f61dd 105 Gene3D G3DSA:2.30.30.40 37 104 2.3E-29 T 29-03-2018 GBCGDNIH2_RS05330 857ae6fcdc0eaa0b12f59099579f61dd 105 SUPERFAMILY SSF82057 33 104 5.95E-25 T 29-03-2018 GBCGDNIH2_RS05330 857ae6fcdc0eaa0b12f59099579f61dd 105 Pfam PF03831 PhnA domain 38 104 1.5E-28 T 29-03-2018 IPR013988 PhnA protein, C-terminal GBCGDNIH2_RS11245 84afc6bcdd361326195b297706414bf8 176 Gene3D G3DSA:3.30.70.790 79 176 2.3E-28 T 29-03-2018 GBCGDNIH2_RS11245 84afc6bcdd361326195b297706414bf8 176 SMART SM00988 6 72 6.9E-17 T 29-03-2018 IPR004029 UreE urease accessory, N-terminal GBCGDNIH2_RS11245 84afc6bcdd361326195b297706414bf8 176 Hamap MF_00822 Urease accessory protein UreE [ureE]. 5 146 23.544 T 29-03-2018 IPR012406 Urease accessory protein UreE GO:0005737|GO:0006457|GO:0016151|GO:0018307 GBCGDNIH2_RS11245 84afc6bcdd361326195b297706414bf8 176 Gene3D G3DSA:2.60.260.20 1 78 6.4E-18 T 29-03-2018 GBCGDNIH2_RS11245 84afc6bcdd361326195b297706414bf8 176 PIRSF PIRSF036402 1 174 7.4E-44 T 29-03-2018 IPR012406 Urease accessory protein UreE GO:0005737|GO:0006457|GO:0016151|GO:0018307 GBCGDNIH2_RS11245 84afc6bcdd361326195b297706414bf8 176 SUPERFAMILY SSF69287 16 78 2.22E-14 T 29-03-2018 IPR004029 UreE urease accessory, N-terminal GBCGDNIH2_RS11245 84afc6bcdd361326195b297706414bf8 176 Pfam PF05194 UreE urease accessory protein, C-terminal domain 79 167 4.2E-25 T 29-03-2018 IPR007864 Urease accessory protein UreE, C-terminal domain GO:0006461|GO:0016151|GO:0019627 GBCGDNIH2_RS11245 84afc6bcdd361326195b297706414bf8 176 Pfam PF02814 UreE urease accessory protein, N-terminal domain 13 72 5.1E-17 T 29-03-2018 IPR004029 UreE urease accessory, N-terminal GBCGDNIH2_RS11245 84afc6bcdd361326195b297706414bf8 176 SUPERFAMILY SSF69737 78 145 1.31E-21 T 29-03-2018 IPR007864 Urease accessory protein UreE, C-terminal domain GO:0006461|GO:0016151|GO:0019627 GBCGDNIH2_RS07710 7aa40b1516359a21af389284aacd6344 322 PRINTS PR01755 Bacterial translocase SecF protein signature 43 58 2.9E-29 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial GBCGDNIH2_RS07710 7aa40b1516359a21af389284aacd6344 322 PRINTS PR01755 Bacterial translocase SecF protein signature 158 172 2.9E-29 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial GBCGDNIH2_RS07710 7aa40b1516359a21af389284aacd6344 322 PRINTS PR01755 Bacterial translocase SecF protein signature 206 224 2.9E-29 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial GBCGDNIH2_RS07710 7aa40b1516359a21af389284aacd6344 322 PRINTS PR01755 Bacterial translocase SecF protein signature 238 253 2.9E-29 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial GBCGDNIH2_RS07710 7aa40b1516359a21af389284aacd6344 322 Pfam PF07549 SecD/SecF GG Motif 39 65 1.2E-6 T 29-03-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site GBCGDNIH2_RS07710 7aa40b1516359a21af389284aacd6344 322 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 44 290 1.9E-78 T 29-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 GBCGDNIH2_RS07710 7aa40b1516359a21af389284aacd6344 322 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 16 301 26.105 T 29-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 GBCGDNIH2_RS07710 7aa40b1516359a21af389284aacd6344 322 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 102 287 1.5E-52 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial GBCGDNIH2_RS07710 7aa40b1516359a21af389284aacd6344 322 Pfam PF02355 Protein export membrane protein 116 299 2.6E-64 T 29-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial GBCGDNIH2_RS07710 7aa40b1516359a21af389284aacd6344 322 Gene3D G3DSA:1.20.1640.10 95 309 3.8E-36 T 29-03-2018 GBCGDNIH2_RS07710 7aa40b1516359a21af389284aacd6344 322 SUPERFAMILY SSF82866 81 302 8.24E-42 T 29-03-2018 GBCGDNIH2_RS02760 4b7e97eb3c77b31628a4c952c51ba0c5 245 Gene3D G3DSA:3.30.420.40 144 193 0.0019 T 29-03-2018 GBCGDNIH2_RS02760 4b7e97eb3c77b31628a4c952c51ba0c5 245 Pfam PF00480 ROK family 15 150 4.2E-18 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 GBCGDNIH2_RS02760 4b7e97eb3c77b31628a4c952c51ba0c5 245 Gene3D G3DSA:3.30.420.40 10 143 1.0E-21 T 29-03-2018 GBCGDNIH2_RS02760 4b7e97eb3c77b31628a4c952c51ba0c5 245 SUPERFAMILY SSF53067 13 240 1.35E-23 T 29-03-2018 GBCGDNIH2_RS10075 37de7686a2dcdb9a0e0662f8ff2ffedf 305 Gene3D G3DSA:3.40.190.10 90 174 2.6E-16 T 29-03-2018 GBCGDNIH2_RS10075 37de7686a2dcdb9a0e0662f8ff2ffedf 305 SUPERFAMILY SSF53850 87 294 9.77E-38 T 29-03-2018 GBCGDNIH2_RS10075 37de7686a2dcdb9a0e0662f8ff2ffedf 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 1.3E-15 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS10075 37de7686a2dcdb9a0e0662f8ff2ffedf 305 Gene3D G3DSA:3.40.190.10 175 265 2.5E-19 T 29-03-2018 GBCGDNIH2_RS10075 37de7686a2dcdb9a0e0662f8ff2ffedf 305 Pfam PF03466 LysR substrate binding domain 87 287 1.4E-36 T 29-03-2018 IPR005119 LysR, substrate-binding GBCGDNIH2_RS10075 37de7686a2dcdb9a0e0662f8ff2ffedf 305 SUPERFAMILY SSF46785 3 85 2.41E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS10075 37de7686a2dcdb9a0e0662f8ff2ffedf 305 Gene3D G3DSA:1.10.10.10 1 89 8.9E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS10075 37de7686a2dcdb9a0e0662f8ff2ffedf 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 28 38 3.2E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS10075 37de7686a2dcdb9a0e0662f8ff2ffedf 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 38 49 3.2E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS10075 37de7686a2dcdb9a0e0662f8ff2ffedf 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 17 28 3.2E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS12165 5efbb9a8e1c0a847c432018a68de5e6d 350 Pfam PF00107 Zinc-binding dehydrogenase 186 308 1.1E-24 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 GBCGDNIH2_RS12165 5efbb9a8e1c0a847c432018a68de5e6d 350 SUPERFAMILY SSF51735 149 312 1.66E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS12165 5efbb9a8e1c0a847c432018a68de5e6d 350 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 179 207 - T 29-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 GBCGDNIH2_RS12165 5efbb9a8e1c0a847c432018a68de5e6d 350 Gene3D G3DSA:3.40.50.720 177 282 2.5E-21 T 29-03-2018 GBCGDNIH2_RS12165 5efbb9a8e1c0a847c432018a68de5e6d 350 Gene3D G3DSA:3.90.180.10 2 176 2.0E-49 T 29-03-2018 GBCGDNIH2_RS12165 5efbb9a8e1c0a847c432018a68de5e6d 350 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 GBCGDNIH2_RS12165 5efbb9a8e1c0a847c432018a68de5e6d 350 SUPERFAMILY SSF50129 14 172 3.93E-51 T 29-03-2018 IPR011032 GroES-like GBCGDNIH2_RS12165 5efbb9a8e1c0a847c432018a68de5e6d 350 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 144 6.2E-27 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 GBCGDNIH2_RS12165 5efbb9a8e1c0a847c432018a68de5e6d 350 Gene3D G3DSA:3.40.50.20 283 341 7.0E-4 T 29-03-2018 GBCGDNIH2_RS12165 5efbb9a8e1c0a847c432018a68de5e6d 350 SMART SM00829 11 342 2.4E-7 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 GBCGDNIH2_RS02855 aa49caadc76c4b386966baef98e8eef7 92 Gene3D G3DSA:3.30.860.10 1 92 4.2E-39 T 29-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02855 aa49caadc76c4b386966baef98e8eef7 92 SUPERFAMILY SSF54570 3 84 7.59E-34 T 29-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02855 aa49caadc76c4b386966baef98e8eef7 92 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 29-03-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02855 aa49caadc76c4b386966baef98e8eef7 92 PIRSF PIRSF002144 1 92 8.4E-34 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02855 aa49caadc76c4b386966baef98e8eef7 92 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 1.3E-20 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02855 aa49caadc76c4b386966baef98e8eef7 92 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 1.3E-20 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02855 aa49caadc76c4b386966baef98e8eef7 92 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 1.3E-20 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02855 aa49caadc76c4b386966baef98e8eef7 92 Pfam PF00203 Ribosomal protein S19 3 83 4.1E-35 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02855 aa49caadc76c4b386966baef98e8eef7 92 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 24.356 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02855 aa49caadc76c4b386966baef98e8eef7 92 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 91 5.0E-41 T 29-03-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 GBCGDNIH2_RS02595 a02e0db7e5a39b11acc329c7e9c5f3ac 183 Gene3D G3DSA:3.40.50.2300 2 124 8.1E-23 T 29-03-2018 GBCGDNIH2_RS02595 a02e0db7e5a39b11acc329c7e9c5f3ac 183 Pfam PF02954 Bacterial regulatory protein, Fis family 141 179 6.5E-12 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 GBCGDNIH2_RS02595 a02e0db7e5a39b11acc329c7e9c5f3ac 183 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 146 163 2.9E-7 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 GBCGDNIH2_RS02595 a02e0db7e5a39b11acc329c7e9c5f3ac 183 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 163 183 2.9E-7 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 GBCGDNIH2_RS02595 a02e0db7e5a39b11acc329c7e9c5f3ac 183 SUPERFAMILY SSF52172 12 124 6.97E-25 T 29-03-2018 IPR011006 CheY-like superfamily GBCGDNIH2_RS02595 a02e0db7e5a39b11acc329c7e9c5f3ac 183 SUPERFAMILY SSF46689 130 180 1.03E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 GBCGDNIH2_RS02595 a02e0db7e5a39b11acc329c7e9c5f3ac 183 SMART SM00448 10 121 9.8E-19 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GBCGDNIH2_RS02595 a02e0db7e5a39b11acc329c7e9c5f3ac 183 Gene3D G3DSA:1.10.10.60 133 179 5.5E-13 T 29-03-2018 GBCGDNIH2_RS02595 a02e0db7e5a39b11acc329c7e9c5f3ac 183 Pfam PF00072 Response regulator receiver domain 13 121 4.6E-17 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GBCGDNIH2_RS00370 330f1bfcbc3d35c75b386f5df5787551 679 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 392 411 1.6E-6 T 29-03-2018 GBCGDNIH2_RS00370 330f1bfcbc3d35c75b386f5df5787551 679 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 474 492 1.6E-6 T 29-03-2018 GBCGDNIH2_RS00370 330f1bfcbc3d35c75b386f5df5787551 679 Gene3D G3DSA:3.20.20.70 2 378 4.9E-100 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS00370 330f1bfcbc3d35c75b386f5df5787551 679 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 8 344 8.1E-64 T 29-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 GBCGDNIH2_RS00370 330f1bfcbc3d35c75b386f5df5787551 679 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 390 501 3.4E-8 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS00370 330f1bfcbc3d35c75b386f5df5787551 679 SUPERFAMILY SSF51905 367 677 1.94E-30 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS00370 330f1bfcbc3d35c75b386f5df5787551 679 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 391 413 1.6E-5 T 29-03-2018 GBCGDNIH2_RS00370 330f1bfcbc3d35c75b386f5df5787551 679 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 653 660 1.6E-5 T 29-03-2018 GBCGDNIH2_RS00370 330f1bfcbc3d35c75b386f5df5787551 679 SUPERFAMILY SSF51395 5 375 7.63E-96 T 29-03-2018 GBCGDNIH2_RS00370 330f1bfcbc3d35c75b386f5df5787551 679 Gene3D G3DSA:3.50.50.60 488 626 1.4E-5 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS00370 330f1bfcbc3d35c75b386f5df5787551 679 Gene3D G3DSA:3.40.50.720 379 487 9.6E-21 T 29-03-2018 GBCGDNIH2_RS03470 adc86f6def1aa212e0ae9b491691b02d 183 Gene3D G3DSA:3.30.1020.10 157 183 5.8E-5 T 29-03-2018 GBCGDNIH2_RS03470 adc86f6def1aa212e0ae9b491691b02d 183 Gene3D G3DSA:3.40.30.10 1 156 6.9E-35 T 29-03-2018 GBCGDNIH2_RS03470 adc86f6def1aa212e0ae9b491691b02d 183 PIRSF PIRSF000239 1 183 2.1E-52 T 29-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 GBCGDNIH2_RS03470 adc86f6def1aa212e0ae9b491691b02d 183 Pfam PF00578 AhpC/TSA family 4 141 4.2E-31 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 GBCGDNIH2_RS03470 adc86f6def1aa212e0ae9b491691b02d 183 SUPERFAMILY SSF52833 1 182 7.74E-54 T 29-03-2018 IPR012336 Thioredoxin-like fold GBCGDNIH2_RS01820 356b829ed95752f88641ef3bb75a8bdf 329 Gene3D G3DSA:3.40.50.410 76 304 3.0E-24 T 29-03-2018 IPR002035 von Willebrand factor, type A GBCGDNIH2_RS01820 356b829ed95752f88641ef3bb75a8bdf 329 SUPERFAMILY SSF53300 82 278 1.04E-20 T 29-03-2018 IPR002035 von Willebrand factor, type A GBCGDNIH2_RS01820 356b829ed95752f88641ef3bb75a8bdf 329 Pfam PF13519 von Willebrand factor type A domain 85 198 9.8E-17 T 29-03-2018 IPR002035 von Willebrand factor, type A GBCGDNIH2_RS01820 356b829ed95752f88641ef3bb75a8bdf 329 SMART SM00327 82 313 3.9E-7 T 29-03-2018 IPR002035 von Willebrand factor, type A GBCGDNIH2_RS08705 44b2e0b2f6d3a3a3a10ebef9d75e6b1a 437 SUPERFAMILY SSF51905 2 348 6.71E-31 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS08705 44b2e0b2f6d3a3a3a10ebef9d75e6b1a 437 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 6.5E-6 T 29-03-2018 GBCGDNIH2_RS08705 44b2e0b2f6d3a3a3a10ebef9d75e6b1a 437 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 173 198 6.5E-6 T 29-03-2018 GBCGDNIH2_RS08705 44b2e0b2f6d3a3a3a10ebef9d75e6b1a 437 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 312 319 6.5E-6 T 29-03-2018 GBCGDNIH2_RS08705 44b2e0b2f6d3a3a3a10ebef9d75e6b1a 437 Gene3D G3DSA:3.50.50.60 4 168 3.9E-13 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS08705 44b2e0b2f6d3a3a3a10ebef9d75e6b1a 437 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 341 8.7E-58 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS08705 44b2e0b2f6d3a3a3a10ebef9d75e6b1a 437 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 173 191 7.0E-12 T 29-03-2018 GBCGDNIH2_RS08705 44b2e0b2f6d3a3a3a10ebef9d75e6b1a 437 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 114 132 7.0E-12 T 29-03-2018 GBCGDNIH2_RS08705 44b2e0b2f6d3a3a3a10ebef9d75e6b1a 437 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 297 319 7.0E-12 T 29-03-2018 GBCGDNIH2_RS08705 44b2e0b2f6d3a3a3a10ebef9d75e6b1a 437 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 7.0E-12 T 29-03-2018 GBCGDNIH2_RS08705 44b2e0b2f6d3a3a3a10ebef9d75e6b1a 437 Gene3D G3DSA:3.40.50.720 171 422 2.3E-34 T 29-03-2018 GBCGDNIH2_RS06225 c92745aace5aa434c32ec86e70530789 151 Gene3D G3DSA:3.30.70.100 7 149 1.6E-32 T 29-03-2018 GBCGDNIH2_RS06225 c92745aace5aa434c32ec86e70530789 151 SUPERFAMILY SSF54909 55 136 4.83E-6 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel GBCGDNIH2_RS12485 404e399e8a4cd291a7ae56c669f78265 255 Gene3D G3DSA:3.40.50.720 1 129 2.2E-20 T 29-03-2018 GBCGDNIH2_RS12485 404e399e8a4cd291a7ae56c669f78265 255 Gene3D G3DSA:3.30.360.10 130 221 2.8E-28 T 29-03-2018 GBCGDNIH2_RS12485 404e399e8a4cd291a7ae56c669f78265 255 SUPERFAMILY SSF55347 115 224 1.98E-30 T 29-03-2018 GBCGDNIH2_RS12485 404e399e8a4cd291a7ae56c669f78265 255 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 1 253 1.5E-60 T 29-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 GBCGDNIH2_RS12485 404e399e8a4cd291a7ae56c669f78265 255 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 115 252 4.2E-41 T 29-03-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 GBCGDNIH2_RS12485 404e399e8a4cd291a7ae56c669f78265 255 SUPERFAMILY SSF51735 224 254 4.15E-32 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS12485 404e399e8a4cd291a7ae56c669f78265 255 SUPERFAMILY SSF51735 1 113 4.15E-32 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS12485 404e399e8a4cd291a7ae56c669f78265 255 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 1 253 29.793 T 29-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 GBCGDNIH2_RS12485 404e399e8a4cd291a7ae56c669f78265 255 PIRSF PIRSF000161 1 255 1.2E-70 T 29-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 GBCGDNIH2_RS12485 404e399e8a4cd291a7ae56c669f78265 255 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 138 155 - T 29-03-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 GBCGDNIH2_RS12485 404e399e8a4cd291a7ae56c669f78265 255 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 1 112 4.6E-19 T 29-03-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 GBCGDNIH2_RS03525 42423013ff8b075c30d36d13982963e7 306 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 3 293 4.3E-78 T 29-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 GBCGDNIH2_RS03525 42423013ff8b075c30d36d13982963e7 306 SUPERFAMILY SSF53328 3 200 6.93E-58 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 GBCGDNIH2_RS03525 42423013ff8b075c30d36d13982963e7 306 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 133 156 - T 29-03-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 GBCGDNIH2_RS03525 42423013ff8b075c30d36d13982963e7 306 Gene3D G3DSA:3.40.50.170 1 202 3.6E-60 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 GBCGDNIH2_RS03525 42423013ff8b075c30d36d13982963e7 306 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 1 295 33.957 T 29-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 GBCGDNIH2_RS03525 42423013ff8b075c30d36d13982963e7 306 Gene3D G3DSA:3.10.25.10 203 304 2.5E-25 T 29-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 GBCGDNIH2_RS03525 42423013ff8b075c30d36d13982963e7 306 SUPERFAMILY SSF50486 201 300 8.63E-25 T 29-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 GBCGDNIH2_RS03525 42423013ff8b075c30d36d13982963e7 306 Pfam PF02911 Formyl transferase, C-terminal domain 200 292 6.1E-22 T 29-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 GBCGDNIH2_RS03525 42423013ff8b075c30d36d13982963e7 306 Pfam PF00551 Formyl transferase 6 181 8.0E-40 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 GBCGDNIH2_RS09745 434b0d3605a68063ffc2d1b1906ed082 183 PIRSF PIRSF032064 18 183 2.5E-32 T 29-03-2018 IPR010593 Protein of unknown function DUF1159 GBCGDNIH2_RS09745 434b0d3605a68063ffc2d1b1906ed082 183 Pfam PF05258 Protein of unknown function (DUF721) 44 129 2.1E-18 T 29-03-2018 IPR007922 Protein of unknown function DUF721/UPF0232 GBCGDNIH2_RS00600 df8a1c28151a6ca5289c62f1c34df509 472 Pfam PF04055 Radical SAM superfamily 173 346 1.0E-30 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 GBCGDNIH2_RS00600 df8a1c28151a6ca5289c62f1c34df509 472 SUPERFAMILY SSF102114 137 392 2.22E-62 T 29-03-2018 GBCGDNIH2_RS00600 df8a1c28151a6ca5289c62f1c34df509 472 SMART SM00729 168 388 2.8E-62 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 GBCGDNIH2_RS00600 df8a1c28151a6ca5289c62f1c34df509 472 Pfam PF01938 TRAM domain 401 459 6.7E-5 T 29-03-2018 IPR002792 TRAM domain GBCGDNIH2_RS00600 df8a1c28151a6ca5289c62f1c34df509 472 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 15 456 3.7E-139 T 29-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 GBCGDNIH2_RS00600 df8a1c28151a6ca5289c62f1c34df509 472 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 14 460 71.28 T 29-03-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 GBCGDNIH2_RS00600 df8a1c28151a6ca5289c62f1c34df509 472 Pfam PF00919 Uncharacterized protein family UPF0004 15 118 6.7E-28 T 29-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 GBCGDNIH2_RS00600 df8a1c28151a6ca5289c62f1c34df509 472 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 172 192 - T 29-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 GBCGDNIH2_RS00600 df8a1c28151a6ca5289c62f1c34df509 472 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 16 458 1.6E-141 T 29-03-2018 GBCGDNIH2_RS00600 df8a1c28151a6ca5289c62f1c34df509 472 Gene3D G3DSA:3.80.30.20 166 402 2.1E-54 T 29-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe GBCGDNIH2_RS00280 e3218d9dfce48e82a8223945d4f1d383 225 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 88 108 - T 29-03-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 GBCGDNIH2_RS00280 e3218d9dfce48e82a8223945d4f1d383 225 Gene3D G3DSA:3.40.1050.10 1 213 3.5E-69 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 GBCGDNIH2_RS00280 e3218d9dfce48e82a8223945d4f1d383 225 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 45 52 - T 29-03-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 GBCGDNIH2_RS00280 e3218d9dfce48e82a8223945d4f1d383 225 Pfam PF00484 Carbonic anhydrase 40 198 2.0E-50 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 GBCGDNIH2_RS00280 e3218d9dfce48e82a8223945d4f1d383 225 SUPERFAMILY SSF53056 5 214 3.92E-67 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 GBCGDNIH2_RS00280 e3218d9dfce48e82a8223945d4f1d383 225 SMART SM00947 33 202 2.1E-65 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 GBCGDNIH2_RS08610 7996c6c0a7bdd034a2a54cd035d77657 179 Gene3D G3DSA:3.10.540.10 5 67 1.5E-23 T 29-03-2018 GBCGDNIH2_RS08610 7996c6c0a7bdd034a2a54cd035d77657 179 PIRSF PIRSF029557 6 177 1.2E-52 T 29-03-2018 IPR010707 Protein of unknown function DUF1285 GBCGDNIH2_RS08610 7996c6c0a7bdd034a2a54cd035d77657 179 Pfam PF06938 Protein of unknown function (DUF1285) 19 167 1.5E-54 T 29-03-2018 IPR010707 Protein of unknown function DUF1285 GBCGDNIH2_RS08610 7996c6c0a7bdd034a2a54cd035d77657 179 Gene3D G3DSA:2.20.70.10 148 172 3.9E-5 T 29-03-2018 GBCGDNIH2_RS08610 7996c6c0a7bdd034a2a54cd035d77657 179 Gene3D G3DSA:2.30.270.10 68 147 5.7E-28 T 29-03-2018 IPR023361 Protein of unknown function DUF1285, beta-roll domain GBCGDNIH2_RS04260 affaa1715be684e8fa64ddbdeaae60d2 275 SUPERFAMILY SSF102215 8 257 5.49E-73 T 29-03-2018 IPR024087 Creatininase-like domain KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 GBCGDNIH2_RS04260 affaa1715be684e8fa64ddbdeaae60d2 275 Gene3D G3DSA:3.40.50.10310 2 259 5.3E-77 T 29-03-2018 IPR024087 Creatininase-like domain KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 GBCGDNIH2_RS04260 affaa1715be684e8fa64ddbdeaae60d2 275 Pfam PF02633 Creatinine amidohydrolase 12 251 3.9E-63 T 29-03-2018 IPR003785 Creatininase/formamide hydrolase KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 GBCGDNIH2_RS00525 1953b9c2dea5d4170e57531a3889cccf 188 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 3 178 2.4E-63 T 29-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 GBCGDNIH2_RS00525 1953b9c2dea5d4170e57531a3889cccf 188 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 180 1.0E-71 T 29-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 GBCGDNIH2_RS00525 1953b9c2dea5d4170e57531a3889cccf 188 Gene3D G3DSA:2.60.120.10 1 184 7.5E-66 T 29-03-2018 IPR014710 RmlC-like jelly roll fold GBCGDNIH2_RS00525 1953b9c2dea5d4170e57531a3889cccf 188 SUPERFAMILY SSF51182 1 186 1.29E-70 T 29-03-2018 IPR011051 RmlC-like cupin domain GBCGDNIH2_RS00525 1953b9c2dea5d4170e57531a3889cccf 188 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 6 176 4.6E-67 T 29-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 GBCGDNIH2_RS09130 96fcc75c6c395792b1ad2ec98344c368 300 Gene3D G3DSA:3.60.10.10 2 295 2.1E-20 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase GBCGDNIH2_RS09130 96fcc75c6c395792b1ad2ec98344c368 300 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 8 243 3.5E-6 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase GBCGDNIH2_RS09130 96fcc75c6c395792b1ad2ec98344c368 300 SUPERFAMILY SSF56219 285 293 1.96E-22 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase GBCGDNIH2_RS09130 96fcc75c6c395792b1ad2ec98344c368 300 SUPERFAMILY SSF56219 5 243 1.96E-22 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase GBCGDNIH2_RS10625 f71a48aa030bce116b17f61d50313c24 207 SUPERFAMILY SSF53328 3 200 1.7E-59 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 GBCGDNIH2_RS10625 f71a48aa030bce116b17f61d50313c24 207 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 3 189 30.415 T 29-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 GBCGDNIH2_RS10625 f71a48aa030bce116b17f61d50313c24 207 Pfam PF00551 Formyl transferase 3 183 3.9E-54 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 GBCGDNIH2_RS10625 f71a48aa030bce116b17f61d50313c24 207 Gene3D G3DSA:3.40.50.170 1 200 1.5E-59 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 GBCGDNIH2_RS10625 f71a48aa030bce116b17f61d50313c24 207 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 3 191 5.4E-66 T 29-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 GBCGDNIH2_RS11735 e2261e772fbf2af72ddc4bef27175dae 214 Hamap MF_01677 Methylthioribulose-1-phosphate dehydratase [mtnB]. 1 214 94.962 T 29-03-2018 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|KEGG: 00400+4.2.1.10|MetaCyc: PWY-4361|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|Reactome: R-HSA-1237112 GBCGDNIH2_RS11735 e2261e772fbf2af72ddc4bef27175dae 214 SMART SM01007 17 208 9.6E-49 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal GBCGDNIH2_RS11735 e2261e772fbf2af72ddc4bef27175dae 214 Gene3D G3DSA:3.40.225.10 4 214 1.8E-41 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal GBCGDNIH2_RS11735 e2261e772fbf2af72ddc4bef27175dae 214 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 18 206 6.1E-40 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal GBCGDNIH2_RS11735 e2261e772fbf2af72ddc4bef27175dae 214 TIGRFAM TIGR03328 salvage_mtnB: methylthioribulose-1-phosphate dehydratase 20 212 1.7E-63 T 29-03-2018 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|KEGG: 00400+4.2.1.10|MetaCyc: PWY-4361|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|Reactome: R-HSA-1237112 GBCGDNIH2_RS11735 e2261e772fbf2af72ddc4bef27175dae 214 SUPERFAMILY SSF53639 14 210 3.92E-40 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal GBCGDNIH2_RS04180 1b42675afa9dab7170a039eeb71c82a4 459 Gene3D G3DSA:3.40.50.620 3 123 5.0E-37 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GBCGDNIH2_RS04180 1b42675afa9dab7170a039eeb71c82a4 459 Gene3D G3DSA:3.40.50.620 124 232 1.9E-24 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GBCGDNIH2_RS04180 1b42675afa9dab7170a039eeb71c82a4 459 SUPERFAMILY SSF52374 3 296 2.33E-105 T 29-03-2018 GBCGDNIH2_RS04180 1b42675afa9dab7170a039eeb71c82a4 459 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 2 459 29.537 T 29-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 GBCGDNIH2_RS04180 1b42675afa9dab7170a039eeb71c82a4 459 Gene3D G3DSA:1.10.1160.10 233 315 4.7E-27 T 29-03-2018 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 GBCGDNIH2_RS04180 1b42675afa9dab7170a039eeb71c82a4 459 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 3 305 9.7E-92 T 29-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 GBCGDNIH2_RS04180 1b42675afa9dab7170a039eeb71c82a4 459 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 3 457 1.3E-149 T 29-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 GBCGDNIH2_RS04180 1b42675afa9dab7170a039eeb71c82a4 459 Gene3D G3DSA:1.10.10.350 371 459 2.5E-21 T 29-03-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 GBCGDNIH2_RS04180 1b42675afa9dab7170a039eeb71c82a4 459 PRINTS PR00987 Glutamyl-tRNA synthetase signature 6 18 6.3E-26 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 GBCGDNIH2_RS04180 1b42675afa9dab7170a039eeb71c82a4 459 PRINTS PR00987 Glutamyl-tRNA synthetase signature 196 204 6.3E-26 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 GBCGDNIH2_RS04180 1b42675afa9dab7170a039eeb71c82a4 459 PRINTS PR00987 Glutamyl-tRNA synthetase signature 20 31 6.3E-26 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 GBCGDNIH2_RS04180 1b42675afa9dab7170a039eeb71c82a4 459 PRINTS PR00987 Glutamyl-tRNA synthetase signature 180 190 6.3E-26 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 GBCGDNIH2_RS04180 1b42675afa9dab7170a039eeb71c82a4 459 PRINTS PR00987 Glutamyl-tRNA synthetase signature 35 48 6.3E-26 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 GBCGDNIH2_RS04180 1b42675afa9dab7170a039eeb71c82a4 459 SUPERFAMILY SSF48163 300 457 2.49E-32 T 29-03-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 GBCGDNIH2_RS04180 1b42675afa9dab7170a039eeb71c82a4 459 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 9 20 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 GBCGDNIH2_RS05355 c82f0ecbd49cb0c577973b59e86ecb43 131 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 61 15.774 T 29-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GBCGDNIH2_RS05355 c82f0ecbd49cb0c577973b59e86ecb43 131 Pfam PF01192 RNA polymerase Rpb6 8 58 3.2E-13 T 29-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 GBCGDNIH2_RS05355 c82f0ecbd49cb0c577973b59e86ecb43 131 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 57 1.0E-17 T 29-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GBCGDNIH2_RS05355 c82f0ecbd49cb0c577973b59e86ecb43 131 Gene3D G3DSA:3.90.940.10 1 126 5.7E-24 T 29-03-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 GBCGDNIH2_RS05355 c82f0ecbd49cb0c577973b59e86ecb43 131 SUPERFAMILY SSF63562 1 72 1.22E-19 T 29-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 GBCGDNIH2_RS05355 c82f0ecbd49cb0c577973b59e86ecb43 131 SMART SM01409 8 60 3.5E-13 T 29-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 GBCGDNIH2_RS07945 9b88288028e8072ae10a952f1fee3ad2 382 Pfam PF03595 Voltage-dependent anion channel 26 364 5.2E-82 T 29-03-2018 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 GBCGDNIH2_RS00195 d8bdf05f3cb9594a7e4b5128321051e9 316 Pfam PF01618 MotA/TolQ/ExbB proton channel family 187 286 6.9E-32 T 29-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 GBCGDNIH2_RS00195 d8bdf05f3cb9594a7e4b5128321051e9 316 TIGRFAM TIGR02797 exbB: tonB-system energizer ExbB 95 303 7.9E-87 T 29-03-2018 IPR014164 TonB-system energizer ExbB type-1 GO:0006810|GO:0016020 GBCGDNIH2_RS07875 948101cae16995aa24e9662ddfb306ba 319 SUPERFAMILY SSF52540 6 37 9.84E-5 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS07875 948101cae16995aa24e9662ddfb306ba 319 SUPERFAMILY SSF52540 149 228 9.84E-5 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS07875 948101cae16995aa24e9662ddfb306ba 319 Pfam PF01715 IPP transferase 39 283 1.1E-66 T 29-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 GBCGDNIH2_RS07875 948101cae16995aa24e9662ddfb306ba 319 Gene3D G3DSA:3.40.50.300 2 186 1.5E-55 T 29-03-2018 GBCGDNIH2_RS07875 948101cae16995aa24e9662ddfb306ba 319 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 7 282 1.6E-71 T 29-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 GBCGDNIH2_RS07875 948101cae16995aa24e9662ddfb306ba 319 SUPERFAMILY SSF52540 8 152 5.92E-19 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS07875 948101cae16995aa24e9662ddfb306ba 319 Gene3D G3DSA:1.10.287.890 200 281 1.9E-20 T 29-03-2018 GBCGDNIH2_RS07875 948101cae16995aa24e9662ddfb306ba 319 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 6 313 25.578 T 29-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 GBCGDNIH2_RS09480 e3c70f34dc570877a5c454bdf5dfb0e3 292 Gene3D G3DSA:3.40.1190.20 1 292 1.6E-71 T 29-03-2018 IPR029056 Ribokinase-like GBCGDNIH2_RS09480 e3c70f34dc570877a5c454bdf5dfb0e3 292 PRINTS PR00990 Ribokinase signature 101 114 7.6E-30 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 GBCGDNIH2_RS09480 e3c70f34dc570877a5c454bdf5dfb0e3 292 PRINTS PR00990 Ribokinase signature 3 24 7.6E-30 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 GBCGDNIH2_RS09480 e3c70f34dc570877a5c454bdf5dfb0e3 292 PRINTS PR00990 Ribokinase signature 30 49 7.6E-30 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 GBCGDNIH2_RS09480 e3c70f34dc570877a5c454bdf5dfb0e3 292 PRINTS PR00990 Ribokinase signature 167 182 7.6E-30 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 GBCGDNIH2_RS09480 e3c70f34dc570877a5c454bdf5dfb0e3 292 PRINTS PR00990 Ribokinase signature 206 217 7.6E-30 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 GBCGDNIH2_RS09480 e3c70f34dc570877a5c454bdf5dfb0e3 292 Pfam PF00294 pfkB family carbohydrate kinase 2 283 3.2E-52 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB GBCGDNIH2_RS09480 e3c70f34dc570877a5c454bdf5dfb0e3 292 Hamap MF_01987 Ribokinase [rbsK]. 1 290 22.398 T 29-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 GBCGDNIH2_RS09480 e3c70f34dc570877a5c454bdf5dfb0e3 292 SUPERFAMILY SSF53613 2 291 1.56E-69 T 29-03-2018 IPR029056 Ribokinase-like GBCGDNIH2_RS10655 f13a6f20f4d7798fcb991e85912c86b9 609 Pfam PF00920 Dehydratase family 70 604 2.2E-157 T 29-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 GBCGDNIH2_RS10655 f13a6f20f4d7798fcb991e85912c86b9 609 SUPERFAMILY SSF143975 7 424 1.44E-140 T 29-03-2018 GBCGDNIH2_RS10655 f13a6f20f4d7798fcb991e85912c86b9 609 TIGRFAM TIGR01196 edd: phosphogluconate dehydratase 7 607 0.0 T 29-03-2018 IPR004786 6-phosphogluconate dehydratase GO:0004456|GO:0009255 KEGG: 00030+4.2.1.12 GBCGDNIH2_RS10655 f13a6f20f4d7798fcb991e85912c86b9 609 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 511 522 - T 29-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 GBCGDNIH2_RS10655 f13a6f20f4d7798fcb991e85912c86b9 609 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 158 168 - T 29-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 GBCGDNIH2_RS10655 f13a6f20f4d7798fcb991e85912c86b9 609 SUPERFAMILY SSF52016 425 607 3.06E-57 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel GBCGDNIH2_RS01770 59151927d9c796fe9ab4f8513bd10b67 313 Pfam PF08009 CDP-alcohol phosphatidyltransferase 2 242 278 3.7E-11 T 29-03-2018 IPR012616 CDP-alcohol phosphatidyltransferase, C-terminal GBCGDNIH2_RS01770 59151927d9c796fe9ab4f8513bd10b67 313 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 88 110 - T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 GBCGDNIH2_RS01770 59151927d9c796fe9ab4f8513bd10b67 313 Pfam PF01066 CDP-alcohol phosphatidyltransferase 46 110 1.3E-13 T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 GBCGDNIH2_RS02280 1bd2121513ca952624881d0855ab6005 412 Gene3D G3DSA:3.40.50.150 7 314 7.9E-29 T 29-03-2018 GBCGDNIH2_RS02280 1bd2121513ca952624881d0855ab6005 412 Pfam PF13649 Methyltransferase domain 59 157 1.3E-13 T 29-03-2018 GBCGDNIH2_RS02280 1bd2121513ca952624881d0855ab6005 412 SUPERFAMILY SSF53335 51 274 2.5E-28 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GBCGDNIH2_RS07180 c294b203b0c116271e9f2b8d5395885f 267 Pfam PF01841 Transglutaminase-like superfamily 130 225 4.4E-20 T 29-03-2018 IPR002931 Transglutaminase-like GBCGDNIH2_RS07180 c294b203b0c116271e9f2b8d5395885f 267 Gene3D G3DSA:3.90.260.10 150 198 7.4E-9 T 29-03-2018 IPR002931 Transglutaminase-like GBCGDNIH2_RS07180 c294b203b0c116271e9f2b8d5395885f 267 SMART SM00460 161 227 6.4E-14 T 29-03-2018 IPR002931 Transglutaminase-like GBCGDNIH2_RS07180 c294b203b0c116271e9f2b8d5395885f 267 SUPERFAMILY SSF54001 48 253 2.66E-43 T 29-03-2018 GBCGDNIH2_RS11645 0c26c53c0bc773f9453295556a5917bb 270 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 13 228 4.3E-12 T 29-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 GBCGDNIH2_RS11645 0c26c53c0bc773f9453295556a5917bb 270 Gene3D G3DSA:3.60.21.10 4 263 4.3E-30 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like GBCGDNIH2_RS11645 0c26c53c0bc773f9453295556a5917bb 270 SUPERFAMILY SSF56300 190 252 2.13E-33 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like GBCGDNIH2_RS11645 0c26c53c0bc773f9453295556a5917bb 270 SUPERFAMILY SSF56300 11 131 2.13E-33 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like GBCGDNIH2_RS05520 89dae939eb13cc091fc24353584e61f9 376 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 94 101 - T 29-03-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 GBCGDNIH2_RS05520 89dae939eb13cc091fc24353584e61f9 376 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 5 212 3.6E-60 T 29-03-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 GBCGDNIH2_RS05520 89dae939eb13cc091fc24353584e61f9 376 SUPERFAMILY SSF69765 217 373 6.67E-62 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 GBCGDNIH2_RS05520 89dae939eb13cc091fc24353584e61f9 376 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 3 211 1.0E-57 T 29-03-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 GBCGDNIH2_RS05520 89dae939eb13cc091fc24353584e61f9 376 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 220 373 1.0E-62 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 GBCGDNIH2_RS05520 89dae939eb13cc091fc24353584e61f9 376 Gene3D G3DSA:3.30.1330.50 206 374 6.1E-73 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 GBCGDNIH2_RS05520 89dae939eb13cc091fc24353584e61f9 376 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 253 268 - T 29-03-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 GBCGDNIH2_RS05520 89dae939eb13cc091fc24353584e61f9 376 SUPERFAMILY SSF53448 3 212 2.5E-54 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS05520 89dae939eb13cc091fc24353584e61f9 376 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 219 374 33.084 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 GBCGDNIH2_RS05520 89dae939eb13cc091fc24353584e61f9 376 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 2 213 37.009 T 29-03-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 GBCGDNIH2_RS05520 89dae939eb13cc091fc24353584e61f9 376 Pfam PF02542 YgbB family 220 372 1.8E-59 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 GBCGDNIH2_RS05520 89dae939eb13cc091fc24353584e61f9 376 Hamap MF_01520 Bifunctional enzyme IspD/IspF [ispDF]. 1 375 42.647 T 29-03-2018 IPR026596 Bifunctional enzyme IspD/IspF KEGG: 00900+4.6.1.12+2.7.7.60|MetaCyc: PWY-7560 GBCGDNIH2_RS05520 89dae939eb13cc091fc24353584e61f9 376 Gene3D G3DSA:3.90.550.10 1 205 1.1E-45 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS03980 d0fb4bbd0c54f5cdbb89a108c72e349a 323 Gene3D G3DSA:3.30.1030.10 130 323 8.7E-84 T 29-03-2018 GBCGDNIH2_RS03980 d0fb4bbd0c54f5cdbb89a108c72e349a 323 Gene3D G3DSA:3.30.1030.10 67 129 8.3E-15 T 29-03-2018 GBCGDNIH2_RS03980 d0fb4bbd0c54f5cdbb89a108c72e349a 323 Pfam PF02289 Cyclohydrolase (MCH) 8 322 4.0E-130 T 29-03-2018 IPR003209 Methenyltetrahydromethanopterin cyclohydrolase GO:0006730|GO:0018759 KEGG: 00680+3.5.4.27|MetaCyc: PWY-1723|MetaCyc: PWY-7784 GBCGDNIH2_RS03980 d0fb4bbd0c54f5cdbb89a108c72e349a 323 Hamap MF_00486 Methenyltetrahydromethanopterin cyclohydrolase [mch]. 1 323 145.548 T 29-03-2018 IPR003209 Methenyltetrahydromethanopterin cyclohydrolase GO:0006730|GO:0018759 KEGG: 00680+3.5.4.27|MetaCyc: PWY-1723|MetaCyc: PWY-7784 GBCGDNIH2_RS03980 d0fb4bbd0c54f5cdbb89a108c72e349a 323 SUPERFAMILY SSF56199 7 322 4.97E-121 T 29-03-2018 GBCGDNIH2_RS03980 d0fb4bbd0c54f5cdbb89a108c72e349a 323 TIGRFAM TIGR03120 one_C_mch: methenyltetrahydromethanopterin cyclohydrolase 8 323 1.5E-119 T 29-03-2018 IPR003209 Methenyltetrahydromethanopterin cyclohydrolase GO:0006730|GO:0018759 KEGG: 00680+3.5.4.27|MetaCyc: PWY-1723|MetaCyc: PWY-7784 GBCGDNIH2_RS03980 d0fb4bbd0c54f5cdbb89a108c72e349a 323 Gene3D G3DSA:3.10.340.11 8 66 1.2E-5 T 29-03-2018 GBCGDNIH2_RS09460 03639004d467a38b7141c47a0327e1d2 550 ProSitePatterns PS00163 Fumarate lyases signature. 467 476 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 GBCGDNIH2_RS09460 03639004d467a38b7141c47a0327e1d2 550 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 385 547 5.3E-55 T 29-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 GBCGDNIH2_RS09460 03639004d467a38b7141c47a0327e1d2 550 Gene3D G3DSA:3.20.130.10 370 547 2.0E-66 T 29-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 GBCGDNIH2_RS09460 03639004d467a38b7141c47a0327e1d2 550 Pfam PF05683 Fumarase C-terminus 343 547 1.7E-90 T 29-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 GBCGDNIH2_RS09460 03639004d467a38b7141c47a0327e1d2 550 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 83 337 2.1E-32 T 29-03-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 GBCGDNIH2_RS09460 03639004d467a38b7141c47a0327e1d2 550 Pfam PF05681 Fumarate hydratase (Fumerase) 56 337 4.9E-85 T 29-03-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 GBCGDNIH2_RS09460 03639004d467a38b7141c47a0327e1d2 550 SUPERFAMILY SSF117457 372 547 1.57E-60 T 29-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 GBCGDNIH2_RS09460 03639004d467a38b7141c47a0327e1d2 550 PIRSF PIRSF001394 37 550 2.4E-211 T 29-03-2018 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384 GBCGDNIH2_RS08485 c646c8dd1ace5a61bff94a158cca2267 957 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 287 321 2.7E-8 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08485 c646c8dd1ace5a61bff94a158cca2267 957 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 99 136 9.6E-9 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08485 c646c8dd1ace5a61bff94a158cca2267 957 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 4 41 3.3E-6 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08485 c646c8dd1ace5a61bff94a158cca2267 957 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 42 79 4.6E-11 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08485 c646c8dd1ace5a61bff94a158cca2267 957 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 358 395 3.1E-5 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08485 c646c8dd1ace5a61bff94a158cca2267 957 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 137 174 2.4E-12 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08485 c646c8dd1ace5a61bff94a158cca2267 957 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 176 211 1.6E-6 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08485 c646c8dd1ace5a61bff94a158cca2267 957 PRINTS PR00313 NodO calcium binding signature 866 875 1.3E-5 T 29-03-2018 GBCGDNIH2_RS08485 c646c8dd1ace5a61bff94a158cca2267 957 PRINTS PR00313 NodO calcium binding signature 785 793 1.3E-5 T 29-03-2018 GBCGDNIH2_RS08485 c646c8dd1ace5a61bff94a158cca2267 957 PRINTS PR00313 NodO calcium binding signature 647 655 1.3E-5 T 29-03-2018 GBCGDNIH2_RS08485 c646c8dd1ace5a61bff94a158cca2267 957 PRINTS PR00313 NodO calcium binding signature 599 610 1.3E-5 T 29-03-2018 GBCGDNIH2_RS08485 c646c8dd1ace5a61bff94a158cca2267 957 SUPERFAMILY SSF51120 762 949 3.27E-10 T 29-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal GBCGDNIH2_RS08485 c646c8dd1ace5a61bff94a158cca2267 957 SUPERFAMILY SSF51120 570 695 1.79E-13 T 29-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal GBCGDNIH2_RS08485 c646c8dd1ace5a61bff94a158cca2267 957 Pfam PF16168 Adhesin of bacterial autotransporter system, probable stalk 123 166 5.7E-8 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08485 c646c8dd1ace5a61bff94a158cca2267 957 Pfam PF16168 Adhesin of bacterial autotransporter system, probable stalk 40 90 1.6E-7 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08485 c646c8dd1ace5a61bff94a158cca2267 957 Gene3D G3DSA:2.150.10.10 783 955 2.3E-8 T 29-03-2018 GBCGDNIH2_RS08485 c646c8dd1ace5a61bff94a158cca2267 957 Gene3D G3DSA:2.150.10.10 504 693 2.1E-12 T 29-03-2018 GBCGDNIH2_RS08485 c646c8dd1ace5a61bff94a158cca2267 957 SUPERFAMILY SSF51126 11 278 2.1E-5 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor GBCGDNIH2_RS04840 0c37e94ef02a1d5c1998400a004be485 110 Gene3D G3DSA:3.30.2390.10 8 64 1.0E-6 T 29-03-2018 IPR035069 TTHA1013/TTHA0281-like GBCGDNIH2_RS04840 0c37e94ef02a1d5c1998400a004be485 110 Gene3D G3DSA:1.10.1220.10 65 110 7.4E-17 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 GBCGDNIH2_RS04840 0c37e94ef02a1d5c1998400a004be485 110 SUPERFAMILY SSF143100 1 76 6.93E-15 T 29-03-2018 IPR035069 TTHA1013/TTHA0281-like GBCGDNIH2_RS04840 0c37e94ef02a1d5c1998400a004be485 110 SUPERFAMILY SSF47598 70 109 7.19E-6 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 GBCGDNIH2_RS04840 0c37e94ef02a1d5c1998400a004be485 110 Pfam PF05534 HicB family 55 105 1.9E-21 T 29-03-2018 IPR008651 Uncharacterised protein family HicB GBCGDNIH2_RS12440 9cd0c953c9c6d166a402e41947fb9c94 395 SUPERFAMILY SSF55973 238 393 1.96E-60 T 29-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 GBCGDNIH2_RS12440 9cd0c953c9c6d166a402e41947fb9c94 395 Gene3D G3DSA:3.30.300.10 264 395 7.6E-40 T 29-03-2018 GBCGDNIH2_RS12440 9cd0c953c9c6d166a402e41947fb9c94 395 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 7 105 1.3E-36 T 29-03-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 GBCGDNIH2_RS12440 9cd0c953c9c6d166a402e41947fb9c94 395 Gene3D G3DSA:3.30.300.10 14 142 6.5E-39 T 29-03-2018 GBCGDNIH2_RS12440 9cd0c953c9c6d166a402e41947fb9c94 395 SUPERFAMILY SSF55973 6 113 8.63E-38 T 29-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 GBCGDNIH2_RS12440 9cd0c953c9c6d166a402e41947fb9c94 395 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 8 392 1.5E-143 T 29-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 GBCGDNIH2_RS12440 9cd0c953c9c6d166a402e41947fb9c94 395 Pfam PF02772 S-adenosylmethionine synthetase, central domain 119 236 3.5E-36 T 29-03-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 GBCGDNIH2_RS12440 9cd0c953c9c6d166a402e41947fb9c94 395 PIRSF PIRSF000497 1 394 1.3E-155 T 29-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 GBCGDNIH2_RS12440 9cd0c953c9c6d166a402e41947fb9c94 395 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 5 393 47.286 T 29-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 GBCGDNIH2_RS12440 9cd0c953c9c6d166a402e41947fb9c94 395 SUPERFAMILY SSF55973 115 237 6.28E-42 T 29-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 GBCGDNIH2_RS12440 9cd0c953c9c6d166a402e41947fb9c94 395 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 264 272 - T 29-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 GBCGDNIH2_RS12440 9cd0c953c9c6d166a402e41947fb9c94 395 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 238 382 4.0E-60 T 29-03-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 GBCGDNIH2_RS12440 9cd0c953c9c6d166a402e41947fb9c94 395 Gene3D G3DSA:3.30.300.10 144 263 7.5E-35 T 29-03-2018 GBCGDNIH2_RS12440 9cd0c953c9c6d166a402e41947fb9c94 395 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 120 130 - T 29-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 GBCGDNIH2_RS07670 6571215f49e2814eb27c2e8f19bbc77e 215 SUPERFAMILY SSF55729 25 178 3.37E-14 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase GBCGDNIH2_RS07670 6571215f49e2814eb27c2e8f19bbc77e 215 Gene3D G3DSA:3.40.630.30 1 199 1.6E-16 T 29-03-2018 GBCGDNIH2_RS05525 c228baf3e611bb8edafe8691284f8533 144 Pfam PF00072 Response regulator receiver domain 31 112 5.2E-16 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GBCGDNIH2_RS05525 c228baf3e611bb8edafe8691284f8533 144 SUPERFAMILY SSF52172 29 137 6.69E-27 T 29-03-2018 IPR011006 CheY-like superfamily GBCGDNIH2_RS05525 c228baf3e611bb8edafe8691284f8533 144 SMART SM00448 29 134 2.7E-15 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GBCGDNIH2_RS05525 c228baf3e611bb8edafe8691284f8533 144 Gene3D G3DSA:3.40.50.2300 24 144 8.4E-25 T 29-03-2018 GBCGDNIH2_RS12465 2157a9b91673711d26b6db48bfba8fd4 669 ProSitePatterns PS00801 Transketolase signature 1. 40 59 - T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 GBCGDNIH2_RS12465 2157a9b91673711d26b6db48bfba8fd4 669 Gene3D G3DSA:3.40.50.970 5 325 1.6E-80 T 29-03-2018 GBCGDNIH2_RS12465 2157a9b91673711d26b6db48bfba8fd4 669 SUPERFAMILY SSF52518 10 210 1.04E-76 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold GBCGDNIH2_RS12465 2157a9b91673711d26b6db48bfba8fd4 669 SUPERFAMILY SSF52518 255 401 1.04E-76 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold GBCGDNIH2_RS12465 2157a9b91673711d26b6db48bfba8fd4 669 ProSitePatterns PS00802 Transketolase signature 2. 445 461 - T 29-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 GBCGDNIH2_RS12465 2157a9b91673711d26b6db48bfba8fd4 669 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 14 659 43.514 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 GBCGDNIH2_RS12465 2157a9b91673711d26b6db48bfba8fd4 669 Gene3D G3DSA:3.40.50.920 522 660 5.0E-32 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 GBCGDNIH2_RS12465 2157a9b91673711d26b6db48bfba8fd4 669 SUPERFAMILY SSF52518 336 531 3.53E-58 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold GBCGDNIH2_RS12465 2157a9b91673711d26b6db48bfba8fd4 669 SMART SM00861 339 504 2.8E-64 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain GBCGDNIH2_RS12465 2157a9b91673711d26b6db48bfba8fd4 669 Gene3D G3DSA:3.40.50.970 326 511 2.3E-44 T 29-03-2018 GBCGDNIH2_RS12465 2157a9b91673711d26b6db48bfba8fd4 669 Pfam PF02779 Transketolase, pyrimidine binding domain 339 499 1.5E-39 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain GBCGDNIH2_RS12465 2157a9b91673711d26b6db48bfba8fd4 669 Pfam PF02780 Transketolase, C-terminal domain 522 650 9.9E-21 T 29-03-2018 IPR033248 Transketolase, C-terminal domain GBCGDNIH2_RS12465 2157a9b91673711d26b6db48bfba8fd4 669 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 18 658 3.3E-229 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 GBCGDNIH2_RS12465 2157a9b91673711d26b6db48bfba8fd4 669 SUPERFAMILY SSF52922 518 658 1.7E-25 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 GBCGDNIH2_RS12465 2157a9b91673711d26b6db48bfba8fd4 669 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 15 296 9.6E-114 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 GBCGDNIH2_RS05095 ce65f5634b6c0c40cc26cf8897088fe9 188 TIGRFAM TIGR00496 frr: ribosome recycling factor 15 188 9.8E-61 T 29-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 GBCGDNIH2_RS05095 ce65f5634b6c0c40cc26cf8897088fe9 188 Pfam PF01765 Ribosome recycling factor 23 185 1.3E-57 T 29-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 GBCGDNIH2_RS05095 ce65f5634b6c0c40cc26cf8897088fe9 188 SUPERFAMILY SSF55194 6 188 2.62E-65 T 29-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 GBCGDNIH2_RS05095 ce65f5634b6c0c40cc26cf8897088fe9 188 Gene3D G3DSA:1.10.132.20 78 187 1.1E-35 T 29-03-2018 GBCGDNIH2_RS05095 ce65f5634b6c0c40cc26cf8897088fe9 188 Gene3D G3DSA:1.10.132.20 5 77 4.6E-7 T 29-03-2018 GBCGDNIH2_RS05095 ce65f5634b6c0c40cc26cf8897088fe9 188 Hamap MF_00040 Ribosome-recycling factor [frr]. 6 188 25.264 T 29-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 GBCGDNIH2_RS12610 7ca6e702b597f9ecf3fb182f06244677 402 Pfam PF00271 Helicase conserved C-terminal domain 238 342 1.4E-29 T 29-03-2018 IPR001650 Helicase, C-terminal GBCGDNIH2_RS12610 7ca6e702b597f9ecf3fb182f06244677 402 Pfam PF00270 DEAD/DEAH box helicase 28 195 1.5E-48 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 GBCGDNIH2_RS12610 7ca6e702b597f9ecf3fb182f06244677 402 SMART SM00487 23 225 8.5E-60 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain GBCGDNIH2_RS12610 7ca6e702b597f9ecf3fb182f06244677 402 Gene3D G3DSA:3.40.50.300 225 401 1.4E-47 T 29-03-2018 GBCGDNIH2_RS12610 7ca6e702b597f9ecf3fb182f06244677 402 SMART SM00490 261 342 3.6E-34 T 29-03-2018 IPR001650 Helicase, C-terminal GBCGDNIH2_RS12610 7ca6e702b597f9ecf3fb182f06244677 402 SUPERFAMILY SSF52540 78 363 1.78E-74 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS12610 7ca6e702b597f9ecf3fb182f06244677 402 Gene3D G3DSA:3.40.50.300 12 224 1.7E-57 T 29-03-2018 GBCGDNIH2_RS12610 7ca6e702b597f9ecf3fb182f06244677 402 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 156 164 - T 29-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site GBCGDNIH2_RS02175 785063da65e56882ddf1efbdf3756b23 334 Gene3D G3DSA:3.30.230.20 41 167 3.8E-44 T 29-03-2018 IPR015870 UDP-3-O-acyl N-acetylglucosamine deacetylase, N-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 GBCGDNIH2_RS02175 785063da65e56882ddf1efbdf3756b23 334 SUPERFAMILY SSF54211 173 316 2.05E-48 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold GBCGDNIH2_RS02175 785063da65e56882ddf1efbdf3756b23 334 SUPERFAMILY SSF54211 42 164 7.28E-40 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold GBCGDNIH2_RS02175 785063da65e56882ddf1efbdf3756b23 334 Pfam PF03331 UDP-3-O-acyl N-acetylglycosamine deacetylase 43 314 1.4E-103 T 29-03-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 GBCGDNIH2_RS02175 785063da65e56882ddf1efbdf3756b23 334 TIGRFAM TIGR00325 lpxC: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 42 326 2.4E-100 T 29-03-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 GBCGDNIH2_RS02175 785063da65e56882ddf1efbdf3756b23 334 Hamap MF_00388 UDP-3-O-acyl-N-acetylglucosamine deacetylase [lpxC]. 41 318 43.368 T 29-03-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 GBCGDNIH2_RS02175 785063da65e56882ddf1efbdf3756b23 334 Gene3D G3DSA:3.30.1700.10 168 333 1.8E-61 T 29-03-2018 IPR011334 UDP-3-O-acyl N-acetylglucosamine deacetylase, C-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 GBCGDNIH2_RS06595 b616918ccab04d47dc5784a7918ec85f 496 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 470 490 3.3E-10 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 GBCGDNIH2_RS06595 b616918ccab04d47dc5784a7918ec85f 496 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 453 470 3.3E-10 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 GBCGDNIH2_RS06595 b616918ccab04d47dc5784a7918ec85f 496 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 354 363 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site GBCGDNIH2_RS06595 b616918ccab04d47dc5784a7918ec85f 496 SMART SM00382 162 305 2.3E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS06595 b616918ccab04d47dc5784a7918ec85f 496 Pfam PF00072 Response regulator receiver domain 6 114 7.5E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GBCGDNIH2_RS06595 b616918ccab04d47dc5784a7918ec85f 496 SUPERFAMILY SSF52540 142 382 5.74E-73 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS06595 b616918ccab04d47dc5784a7918ec85f 496 Gene3D G3DSA:1.10.10.60 399 490 1.3E-16 T 29-03-2018 GBCGDNIH2_RS06595 b616918ccab04d47dc5784a7918ec85f 496 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 228 243 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 GBCGDNIH2_RS06595 b616918ccab04d47dc5784a7918ec85f 496 SMART SM00448 4 115 2.4E-32 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GBCGDNIH2_RS06595 b616918ccab04d47dc5784a7918ec85f 496 Pfam PF02954 Bacterial regulatory protein, Fis family 447 485 2.4E-13 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 GBCGDNIH2_RS06595 b616918ccab04d47dc5784a7918ec85f 496 Gene3D G3DSA:3.40.50.300 137 314 1.0E-27 T 29-03-2018 GBCGDNIH2_RS06595 b616918ccab04d47dc5784a7918ec85f 496 TIGRFAM TIGR01818 ntrC: nitrogen regulation protein NR(I) 6 487 1.5E-208 T 29-03-2018 IPR010114 Signal transduction response regulator, nitrogen regulation NR(I) GO:0000156|GO:0000160|GO:0003677|GO:0005524|GO:0006808 GBCGDNIH2_RS06595 b616918ccab04d47dc5784a7918ec85f 496 SUPERFAMILY SSF52172 1 186 3.42E-43 T 29-03-2018 IPR011006 CheY-like superfamily GBCGDNIH2_RS06595 b616918ccab04d47dc5784a7918ec85f 496 Gene3D G3DSA:1.10.8.60 315 386 4.7E-23 T 29-03-2018 GBCGDNIH2_RS06595 b616918ccab04d47dc5784a7918ec85f 496 Pfam PF00158 Sigma-54 interaction domain 142 308 2.7E-70 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 GBCGDNIH2_RS06595 b616918ccab04d47dc5784a7918ec85f 496 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 166 179 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 GBCGDNIH2_RS06595 b616918ccab04d47dc5784a7918ec85f 496 SUPERFAMILY SSF46689 437 489 2.15E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 GBCGDNIH2_RS06595 b616918ccab04d47dc5784a7918ec85f 496 SUPERFAMILY SSF46689 354 392 2.15E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 GBCGDNIH2_RS06595 b616918ccab04d47dc5784a7918ec85f 496 Gene3D G3DSA:3.40.50.2300 1 123 5.6E-31 T 29-03-2018 GBCGDNIH2_RS05080 fc8b3e1c23d94050aedf7e9343b6671a 470 Pfam PF02321 Outer membrane efflux protein 248 430 8.3E-23 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 GBCGDNIH2_RS05080 fc8b3e1c23d94050aedf7e9343b6671a 470 Pfam PF02321 Outer membrane efflux protein 32 225 2.7E-26 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 GBCGDNIH2_RS05080 fc8b3e1c23d94050aedf7e9343b6671a 470 SUPERFAMILY SSF56954 7 432 3.92E-72 T 29-03-2018 GBCGDNIH2_RS05080 fc8b3e1c23d94050aedf7e9343b6671a 470 TIGRFAM TIGR01844 type_I_sec_TolC: type I secretion outer membrane protein, TolC family 31 439 9.4E-84 T 29-03-2018 IPR010130 Type I secretion outer membrane protein, TolC GO:0006810|GO:0019867 GBCGDNIH2_RS05080 fc8b3e1c23d94050aedf7e9343b6671a 470 Gene3D G3DSA:1.20.1600.10 18 436 3.0E-63 T 29-03-2018 GBCGDNIH2_RS02680 b0f5028335b88945e32c619dbd37b741 784 Pfam PF03709 Orn/Lys/Arg decarboxylase, N-terminal domain 22 136 3.6E-26 T 29-03-2018 IPR005308 Orn/Lys/Arg decarboxylase, N-terminal GO:0016831 GBCGDNIH2_RS02680 b0f5028335b88945e32c619dbd37b741 784 SUPERFAMILY SSF53383 142 629 1.21E-105 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase GBCGDNIH2_RS02680 b0f5028335b88945e32c619dbd37b741 784 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 637 769 1.5E-48 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 GBCGDNIH2_RS02680 b0f5028335b88945e32c619dbd37b741 784 Gene3D G3DSA:3.40.640.10 142 458 2.3E-40 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GBCGDNIH2_RS02680 b0f5028335b88945e32c619dbd37b741 784 Gene3D G3DSA:3.90.1150.10 459 661 1.7E-54 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 GBCGDNIH2_RS02680 b0f5028335b88945e32c619dbd37b741 784 SUPERFAMILY SSF55904 635 783 4.97E-40 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 GBCGDNIH2_RS02680 b0f5028335b88945e32c619dbd37b741 784 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 142 611 6.8E-148 T 29-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 GBCGDNIH2_RS02680 b0f5028335b88945e32c619dbd37b741 784 ProSitePatterns PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site. 388 402 - T 29-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 GBCGDNIH2_RS02680 b0f5028335b88945e32c619dbd37b741 784 Gene3D G3DSA:3.90.100.10 662 784 2.3E-32 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 GBCGDNIH2_RS02680 b0f5028335b88945e32c619dbd37b741 784 PIRSF PIRSF009393 3 783 1.6E-271 T 29-03-2018 IPR011193 Ornithine/lysine/arginine decarboxylase GO:0005737|GO:0006520|GO:0016831 GBCGDNIH2_RS00410 7f55a2e2240899763b3f2d6566a1ac30 89 Pfam PF04267 Sarcosine oxidase, delta subunit family 3 83 3.2E-38 T 29-03-2018 IPR006279 Sarcosine oxidase, delta subunit, heterotetrameric GO:0008115|GO:0046653 KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 GBCGDNIH2_RS00410 7f55a2e2240899763b3f2d6566a1ac30 89 Gene3D G3DSA:3.30.2270.10 1 88 1.0E-38 T 29-03-2018 GBCGDNIH2_RS00410 7f55a2e2240899763b3f2d6566a1ac30 89 TIGRFAM TIGR01374 soxD: sarcosine oxidase, delta subunit family 3 86 2.1E-39 T 29-03-2018 IPR006279 Sarcosine oxidase, delta subunit, heterotetrameric GO:0008115|GO:0046653 KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 GBCGDNIH2_RS02435 a91a98f7fa30084af66e654df595813e 233 TIGRFAM TIGR01222 minC: septum site-determining protein MinC 24 231 4.1E-48 T 29-03-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 GBCGDNIH2_RS02435 a91a98f7fa30084af66e654df595813e 233 Hamap MF_00267 Probable septum site-determining protein MinC [minC]. 10 233 23.398 T 29-03-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 GBCGDNIH2_RS02435 a91a98f7fa30084af66e654df595813e 233 Pfam PF05209 Septum formation inhibitor MinC, N-terminal domain 20 91 1.8E-6 T 29-03-2018 IPR007874 Septum formation inhibitor MinC, N-terminal GO:0051302 GBCGDNIH2_RS02435 a91a98f7fa30084af66e654df595813e 233 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 129 229 1.5E-29 T 29-03-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 GBCGDNIH2_RS02435 a91a98f7fa30084af66e654df595813e 233 SUPERFAMILY SSF63848 128 231 2.22E-28 T 29-03-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 GBCGDNIH2_RS02435 a91a98f7fa30084af66e654df595813e 233 Gene3D G3DSA:2.160.20.70 115 233 1.1E-30 T 29-03-2018 GBCGDNIH2_RS10395 001066ae90933f11eb05f1f30e7257b5 619 PIRSF PIRSF002741 45 616 3.0E-94 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 GBCGDNIH2_RS10395 001066ae90933f11eb05f1f30e7257b5 619 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 124 529 1.2E-67 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain GBCGDNIH2_RS10395 001066ae90933f11eb05f1f30e7257b5 619 Gene3D G3DSA:3.40.190.10 228 340 1.0E-16 T 29-03-2018 GBCGDNIH2_RS10395 001066ae90933f11eb05f1f30e7257b5 619 Gene3D G3DSA:3.10.105.10 341 584 1.2E-42 T 29-03-2018 GBCGDNIH2_RS10395 001066ae90933f11eb05f1f30e7257b5 619 Gene3D G3DSA:3.90.76.10 88 227 9.1E-27 T 29-03-2018 GBCGDNIH2_RS10395 001066ae90933f11eb05f1f30e7257b5 619 SUPERFAMILY SSF53850 73 612 2.9E-109 T 29-03-2018 GBCGDNIH2_RS09880 8d87919f066f0a243846876a9ce2ff53 326 Pfam PF01758 Sodium Bile acid symporter family 42 213 8.3E-35 T 29-03-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 GBCGDNIH2_RS00445 de069c824d0f190d6f2d8a3e4d85fb07 169 Gene3D G3DSA:2.60.40.1470 40 165 1.9E-45 T 29-03-2018 IPR007474 ApaG domain GBCGDNIH2_RS00445 de069c824d0f190d6f2d8a3e4d85fb07 169 Pfam PF04379 ApaG domain 58 142 6.8E-34 T 29-03-2018 IPR007474 ApaG domain GBCGDNIH2_RS00445 de069c824d0f190d6f2d8a3e4d85fb07 169 Hamap MF_00791 Protein ApaG [apaG]. 40 169 30.522 T 29-03-2018 IPR023065 Uncharacterised protein family ApaG GBCGDNIH2_RS00445 de069c824d0f190d6f2d8a3e4d85fb07 169 SUPERFAMILY SSF110069 43 166 1.96E-47 T 29-03-2018 IPR007474 ApaG domain GBCGDNIH2_RS06865 ee684cc1cce119446e974c36800d2190 1143 SMART SM00481 7 74 1.3E-16 T 29-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal GBCGDNIH2_RS06865 ee684cc1cce119446e974c36800d2190 1143 Pfam PF14579 Helix-hairpin-helix motif 796 888 5.1E-27 T 29-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GBCGDNIH2_RS06865 ee684cc1cce119446e974c36800d2190 1143 Gene3D G3DSA:1.10.150.280 780 885 8.9E-6 T 29-03-2018 GBCGDNIH2_RS06865 ee684cc1cce119446e974c36800d2190 1143 Pfam PF02811 PHP domain 8 175 1.5E-31 T 29-03-2018 IPR004013 PHP domain GO:0003824 GBCGDNIH2_RS06865 ee684cc1cce119446e974c36800d2190 1143 Gene3D G3DSA:2.40.50.140 968 1063 2.9E-11 T 29-03-2018 GBCGDNIH2_RS06865 ee684cc1cce119446e974c36800d2190 1143 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 295 722 9.8E-169 T 29-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GBCGDNIH2_RS06865 ee684cc1cce119446e974c36800d2190 1143 SUPERFAMILY SSF89550 6 264 1.08E-11 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 GBCGDNIH2_RS06865 ee684cc1cce119446e974c36800d2190 1143 Gene3D G3DSA:3.20.20.140 5 254 5.2E-33 T 29-03-2018 GBCGDNIH2_RS06865 ee684cc1cce119446e974c36800d2190 1143 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 6 1021 0.0 T 29-03-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GBCGDNIH2_RS10060 a231a05dbcd683ab84485e96773799c8 255 SUPERFAMILY SSF48613 16 254 2.08E-68 T 29-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 GBCGDNIH2_RS10060 a231a05dbcd683ab84485e96773799c8 255 Gene3D G3DSA:1.20.910.10 11 245 1.6E-34 T 29-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 GBCGDNIH2_RS10060 a231a05dbcd683ab84485e96773799c8 255 TIGRFAM TIGR02111 PQQ_syn_pqqC: coenzyme PQQ biosynthesis protein C 17 254 1.4E-117 T 29-03-2018 IPR011845 Coenzyme PQQ biosynthesis protein C GO:0018189|GO:0055114 MetaCyc: PWY-6420 GBCGDNIH2_RS10060 a231a05dbcd683ab84485e96773799c8 255 Hamap MF_00654 Pyrroloquinoline-quinone synthase [pqqC]. 1 255 128.441 T 29-03-2018 IPR011845 Coenzyme PQQ biosynthesis protein C GO:0018189|GO:0055114 MetaCyc: PWY-6420 GBCGDNIH2_RS10060 a231a05dbcd683ab84485e96773799c8 255 Pfam PF03070 TENA/THI-4/PQQC family 24 234 3.2E-59 T 29-03-2018 IPR004305 Thiaminase-2/PQQC GBCGDNIH2_RS01200 448c65435fe6881b6ec00b8aaf081797 238 Pfam PF12804 MobA-like NTP transferase domain 3 133 2.8E-16 T 29-03-2018 IPR025877 MobA-like NTP transferase GBCGDNIH2_RS01200 448c65435fe6881b6ec00b8aaf081797 238 Gene3D G3DSA:3.90.550.10 1 238 3.3E-34 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS01200 448c65435fe6881b6ec00b8aaf081797 238 SUPERFAMILY SSF53448 1 236 4.96E-37 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS12420 e6e1d52cf940f96cd2ed9b1f922e5435 178 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 10 158 21.121 T 29-03-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 GBCGDNIH2_RS12420 e6e1d52cf940f96cd2ed9b1f922e5435 178 Pfam PF17384 RimP C-terminal SH3 domain 91 157 3.1E-10 T 29-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal GBCGDNIH2_RS12420 e6e1d52cf940f96cd2ed9b1f922e5435 178 Pfam PF02576 RimP N-terminal domain 15 88 2.6E-18 T 29-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal GBCGDNIH2_RS12420 e6e1d52cf940f96cd2ed9b1f922e5435 178 SUPERFAMILY SSF74942 89 158 1.31E-12 T 29-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal GBCGDNIH2_RS12420 e6e1d52cf940f96cd2ed9b1f922e5435 178 Gene3D G3DSA:2.30.30.180 93 156 1.1E-12 T 29-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal GBCGDNIH2_RS12420 e6e1d52cf940f96cd2ed9b1f922e5435 178 Gene3D G3DSA:3.30.300.70 3 84 8.1E-19 T 29-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal GBCGDNIH2_RS12420 e6e1d52cf940f96cd2ed9b1f922e5435 178 SUPERFAMILY SSF75420 5 88 1.83E-17 T 29-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal GBCGDNIH2_RS10690 fe2b82e55583816f184ebad331ccc792 342 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 10 336 1.0E-99 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 GBCGDNIH2_RS10690 fe2b82e55583816f184ebad331ccc792 342 SMART SM01329 6 337 2.8E-163 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 GBCGDNIH2_RS10690 fe2b82e55583816f184ebad331ccc792 342 Gene3D G3DSA:3.40.718.10 1 342 1.4E-125 T 29-03-2018 GBCGDNIH2_RS10690 fe2b82e55583816f184ebad331ccc792 342 SUPERFAMILY SSF53659 5 341 8.82E-120 T 29-03-2018 GBCGDNIH2_RS10690 fe2b82e55583816f184ebad331ccc792 342 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 233 252 - T 29-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 GBCGDNIH2_RS00375 d39e1223286a184962df6a2d6788ef3f 324 SMART SM00342 237 320 2.2E-25 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 GBCGDNIH2_RS00375 d39e1223286a184962df6a2d6788ef3f 324 SUPERFAMILY SSF46689 273 320 9.41E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 GBCGDNIH2_RS00375 d39e1223286a184962df6a2d6788ef3f 324 Pfam PF01965 DJ-1/PfpI family 47 181 8.8E-13 T 29-03-2018 IPR002818 DJ-1/PfpI GBCGDNIH2_RS00375 d39e1223286a184962df6a2d6788ef3f 324 Gene3D G3DSA:3.40.50.880 13 223 7.9E-45 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like GBCGDNIH2_RS00375 d39e1223286a184962df6a2d6788ef3f 324 SUPERFAMILY SSF46689 216 269 1.48E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 GBCGDNIH2_RS00375 d39e1223286a184962df6a2d6788ef3f 324 Gene3D G3DSA:1.10.10.60 275 320 1.0E-8 T 29-03-2018 GBCGDNIH2_RS00375 d39e1223286a184962df6a2d6788ef3f 324 Pfam PF12833 Helix-turn-helix domain 244 318 4.3E-22 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 GBCGDNIH2_RS00375 d39e1223286a184962df6a2d6788ef3f 324 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 274 316 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 GBCGDNIH2_RS00375 d39e1223286a184962df6a2d6788ef3f 324 Gene3D G3DSA:1.10.10.60 224 274 2.2E-15 T 29-03-2018 GBCGDNIH2_RS00375 d39e1223286a184962df6a2d6788ef3f 324 SUPERFAMILY SSF52317 14 200 1.68E-42 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like GBCGDNIH2_RS11210 eb43dbe895193ad4f03ade76735a5ef8 736 Gene3D G3DSA:1.50.10.10 284 459 1.5E-27 T 29-03-2018 GBCGDNIH2_RS11210 eb43dbe895193ad4f03ade76735a5ef8 736 Gene3D G3DSA:1.50.10.10 460 668 7.3E-42 T 29-03-2018 GBCGDNIH2_RS11210 eb43dbe895193ad4f03ade76735a5ef8 736 Pfam PF06202 Amylo-alpha-1,6-glucosidase 305 662 8.2E-9 T 29-03-2018 IPR032790 Glycogen debranching enzyme, C-terminal KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-6798695|Reactome: R-HSA-70221 GBCGDNIH2_RS11210 eb43dbe895193ad4f03ade76735a5ef8 736 Pfam PF14742 N-terminal domain of (some) glycogen debranching enzymes 47 237 4.1E-47 T 29-03-2018 IPR032856 Putative glycogen debranching enzyme, N-terminal GBCGDNIH2_RS11210 eb43dbe895193ad4f03ade76735a5ef8 736 SUPERFAMILY SSF48208 278 682 4.16E-85 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 GBCGDNIH2_RS09700 9368ba4c85d3b416fef20b337fb1eec4 228 Pfam PF01965 DJ-1/PfpI family 6 164 7.6E-30 T 29-03-2018 IPR002818 DJ-1/PfpI GBCGDNIH2_RS09700 9368ba4c85d3b416fef20b337fb1eec4 228 Gene3D G3DSA:3.40.50.880 1 228 1.3E-57 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like GBCGDNIH2_RS09700 9368ba4c85d3b416fef20b337fb1eec4 228 SUPERFAMILY SSF52317 4 188 6.79E-50 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like GBCGDNIH2_RS07870 6acf5ba7f032cb085a51f2dc58f580e6 610 SUPERFAMILY SSF52467 202 375 1.42E-60 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain GBCGDNIH2_RS07870 6acf5ba7f032cb085a51f2dc58f580e6 610 SUPERFAMILY SSF52518 390 592 2.95E-64 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold GBCGDNIH2_RS07870 6acf5ba7f032cb085a51f2dc58f580e6 610 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 21 181 6.9E-59 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 GBCGDNIH2_RS07870 6acf5ba7f032cb085a51f2dc58f580e6 610 Gene3D G3DSA:3.40.50.970 368 580 2.0E-44 T 29-03-2018 GBCGDNIH2_RS07870 6acf5ba7f032cb085a51f2dc58f580e6 610 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 416 562 1.9E-44 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 GBCGDNIH2_RS07870 6acf5ba7f032cb085a51f2dc58f580e6 610 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 209 346 1.7E-42 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 GBCGDNIH2_RS07870 6acf5ba7f032cb085a51f2dc58f580e6 610 Gene3D G3DSA:3.40.50.1220 212 367 1.3E-51 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain GBCGDNIH2_RS07870 6acf5ba7f032cb085a51f2dc58f580e6 610 SUPERFAMILY SSF52518 16 195 3.23E-64 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold GBCGDNIH2_RS07870 6acf5ba7f032cb085a51f2dc58f580e6 610 Gene3D G3DSA:3.40.50.970 12 211 1.3E-63 T 29-03-2018 GBCGDNIH2_RS07870 6acf5ba7f032cb085a51f2dc58f580e6 610 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 20 585 1.3E-234 T 29-03-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 GBCGDNIH2_RS12215 574cc1f87dd39a70fab6df9630bc843d 684 SUPERFAMILY SSF53955 39 228 3.66E-43 T 29-03-2018 IPR023346 Lysozyme-like domain GBCGDNIH2_RS12215 574cc1f87dd39a70fab6df9630bc843d 684 Gene3D G3DSA:1.10.3810.10 37 234 2.2E-36 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 GBCGDNIH2_RS12215 574cc1f87dd39a70fab6df9630bc843d 684 Pfam PF06832 Penicillin-Binding Protein C-terminus Family 587 671 4.4E-18 T 29-03-2018 IPR009647 Penicillin-binding, C-terminal GBCGDNIH2_RS12215 574cc1f87dd39a70fab6df9630bc843d 684 Pfam PF00912 Transglycosylase 63 225 2.2E-37 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 GBCGDNIH2_RS12215 574cc1f87dd39a70fab6df9630bc843d 684 TIGRFAM TIGR02073 PBP_1c: penicillin-binding protein 1C 29 572 4.0E-165 T 29-03-2018 IPR011815 Penicillin-binding protein 1C GO:0008955|GO:0009252 GBCGDNIH2_RS12215 574cc1f87dd39a70fab6df9630bc843d 684 SUPERFAMILY SSF56601 209 567 2.62E-74 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like GBCGDNIH2_RS12215 574cc1f87dd39a70fab6df9630bc843d 684 Pfam PF00905 Penicillin binding protein transpeptidase domain 295 515 6.9E-17 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 GBCGDNIH2_RS12215 574cc1f87dd39a70fab6df9630bc843d 684 Gene3D G3DSA:3.40.710.10 250 576 1.1E-58 T 29-03-2018 GBCGDNIH2_RS04630 7a625a46d2985c0384bfc10c4a9d315c 365 SUPERFAMILY SSF56281 12 322 1.21E-60 T 29-03-2018 IPR001279 Metallo-beta-lactamase GBCGDNIH2_RS04630 7a625a46d2985c0384bfc10c4a9d315c 365 Gene3D G3DSA:3.60.15.10 20 316 2.1E-24 T 29-03-2018 IPR001279 Metallo-beta-lactamase GBCGDNIH2_RS04630 7a625a46d2985c0384bfc10c4a9d315c 365 TIGRFAM TIGR04122 Xnuc_lig_assoc: putative exonuclease, DNA ligase-associated 11 338 6.6E-135 T 29-03-2018 IPR026360 Putative exonuclease, DNA ligase-associated GBCGDNIH2_RS09305 aaaef6f228f867e8e8551718a215ba2f 371 Pfam PF12889 Protein of unknown function (DUF3829) 90 367 7.3E-66 T 29-03-2018 IPR024291 Protein of unknown function DUF3829 GBCGDNIH2_RS01290 2c728173b247945aab4ae2524e95a567 293 Pfam PF00248 Aldo/keto reductase family 22 283 1.4E-59 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain GBCGDNIH2_RS01290 2c728173b247945aab4ae2524e95a567 293 SUPERFAMILY SSF51430 15 283 2.62E-70 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain GBCGDNIH2_RS01290 2c728173b247945aab4ae2524e95a567 293 Gene3D G3DSA:3.20.20.100 14 288 2.0E-69 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain GBCGDNIH2_RS01290 2c728173b247945aab4ae2524e95a567 293 PRINTS PR00069 Aldo-keto reductase signature 147 164 4.0E-6 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 GBCGDNIH2_RS01290 2c728173b247945aab4ae2524e95a567 293 PRINTS PR00069 Aldo-keto reductase signature 218 242 4.0E-6 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 GBCGDNIH2_RS01290 2c728173b247945aab4ae2524e95a567 293 PRINTS PR00069 Aldo-keto reductase signature 116 134 4.0E-6 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 GBCGDNIH2_RS06135 4ef0677f14b33fe82fdec8eceb119157 456 SUPERFAMILY SSF52374 8 320 3.49E-87 T 29-03-2018 GBCGDNIH2_RS06135 4ef0677f14b33fe82fdec8eceb119157 456 SMART SM00840 347 401 1.0E-8 T 29-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 GBCGDNIH2_RS06135 4ef0677f14b33fe82fdec8eceb119157 456 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 65 74 8.8E-30 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 GBCGDNIH2_RS06135 4ef0677f14b33fe82fdec8eceb119157 456 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 29 40 8.8E-30 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 GBCGDNIH2_RS06135 4ef0677f14b33fe82fdec8eceb119157 456 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 229 250 8.8E-30 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 GBCGDNIH2_RS06135 4ef0677f14b33fe82fdec8eceb119157 456 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 198 216 8.8E-30 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 GBCGDNIH2_RS06135 4ef0677f14b33fe82fdec8eceb119157 456 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 19 320 3.5E-114 T 29-03-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 GBCGDNIH2_RS06135 4ef0677f14b33fe82fdec8eceb119157 456 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 6 455 36.303 T 29-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 GBCGDNIH2_RS06135 4ef0677f14b33fe82fdec8eceb119157 456 Pfam PF09190 DALR domain 350 401 9.0E-7 T 29-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 GBCGDNIH2_RS06135 4ef0677f14b33fe82fdec8eceb119157 456 Gene3D G3DSA:1.20.120.640 314 419 1.7E-12 T 29-03-2018 GBCGDNIH2_RS06135 4ef0677f14b33fe82fdec8eceb119157 456 Gene3D G3DSA:3.40.50.620 2 313 5.7E-80 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GBCGDNIH2_RS06135 4ef0677f14b33fe82fdec8eceb119157 456 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 7 454 2.1E-143 T 29-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 GBCGDNIH2_RS06135 4ef0677f14b33fe82fdec8eceb119157 456 SUPERFAMILY SSF47323 324 454 5.23E-28 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 GBCGDNIH2_RS05540 8ff5b3a3ecba04e786b42f089431bd8a 130 Pfam PF05610 Protein of unknown function (DUF779) 16 109 1.6E-48 T 29-03-2018 IPR008497 Protein of unknown function DUF779 GBCGDNIH2_RS05540 8ff5b3a3ecba04e786b42f089431bd8a 130 PIRSF PIRSF009151 1 123 3.2E-61 T 29-03-2018 IPR008497 Protein of unknown function DUF779 GBCGDNIH2_RS02580 e270fa5783023efd79f37aa314283909 418 SUPERFAMILY SSF54373 270 360 2.88E-19 T 29-03-2018 GBCGDNIH2_RS02580 e270fa5783023efd79f37aa314283909 418 Gene3D G3DSA:3.50.50.60 1 418 1.2E-50 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS02580 e270fa5783023efd79f37aa314283909 418 Hamap MF_01202 D-amino acid dehydrogenase [dadA]. 1 411 48.491 T 29-03-2018 IPR023080 D-amino acid dehydrogenase DadA GO:0008718|GO:0019478|GO:0055114 GBCGDNIH2_RS02580 e270fa5783023efd79f37aa314283909 418 SUPERFAMILY SSF51905 2 54 8.67E-54 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS02580 e270fa5783023efd79f37aa314283909 418 SUPERFAMILY SSF51905 360 416 8.67E-54 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS02580 e270fa5783023efd79f37aa314283909 418 SUPERFAMILY SSF51905 107 270 8.67E-54 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS02580 e270fa5783023efd79f37aa314283909 418 Pfam PF01266 FAD dependent oxidoreductase 3 398 4.8E-75 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 GBCGDNIH2_RS04985 69cc9a7a448a238efb53fd180b9a7be2 709 SUPERFAMILY SSF81296 12 155 4.76E-45 T 29-03-2018 IPR014756 Immunoglobulin E-set GBCGDNIH2_RS04985 69cc9a7a448a238efb53fd180b9a7be2 709 SMART SM00642 170 577 6.7E-9 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 GBCGDNIH2_RS04985 69cc9a7a448a238efb53fd180b9a7be2 709 SUPERFAMILY SSF51445 144 480 2.0E-137 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily GBCGDNIH2_RS04985 69cc9a7a448a238efb53fd180b9a7be2 709 SUPERFAMILY SSF51445 509 585 2.0E-137 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily GBCGDNIH2_RS04985 69cc9a7a448a238efb53fd180b9a7be2 709 Gene3D G3DSA:3.20.20.80 148 589 1.4E-111 T 29-03-2018 GBCGDNIH2_RS04985 69cc9a7a448a238efb53fd180b9a7be2 709 Gene3D G3DSA:2.60.40.1180 590 709 2.4E-27 T 29-03-2018 GBCGDNIH2_RS04985 69cc9a7a448a238efb53fd180b9a7be2 709 SUPERFAMILY SSF51011 598 705 6.19E-24 T 29-03-2018 GBCGDNIH2_RS04985 69cc9a7a448a238efb53fd180b9a7be2 709 Pfam PF00128 Alpha amylase, catalytic domain 189 288 1.5E-7 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 GBCGDNIH2_RS04985 69cc9a7a448a238efb53fd180b9a7be2 709 Gene3D G3DSA:2.60.40.10 13 147 1.7E-41 T 29-03-2018 IPR013783 Immunoglobulin-like fold GBCGDNIH2_RS04985 69cc9a7a448a238efb53fd180b9a7be2 709 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 18 104 6.9E-15 T 29-03-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077 GBCGDNIH2_RS04985 69cc9a7a448a238efb53fd180b9a7be2 709 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 12 705 0.0 T 29-03-2018 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 GBCGDNIH2_RS03310 be8e074b8c65908baf95b2b2b0c032f8 389 SUPERFAMILY SSF53756 16 388 1.04E-83 T 29-03-2018 GBCGDNIH2_RS03310 be8e074b8c65908baf95b2b2b0c032f8 389 Gene3D G3DSA:3.40.50.2000 14 195 2.3E-21 T 29-03-2018 GBCGDNIH2_RS03310 be8e074b8c65908baf95b2b2b0c032f8 389 Gene3D G3DSA:3.40.50.2000 196 372 1.6E-40 T 29-03-2018 GBCGDNIH2_RS03310 be8e074b8c65908baf95b2b2b0c032f8 389 Pfam PF00534 Glycosyl transferases group 1 209 359 4.9E-30 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 GBCGDNIH2_RS03310 be8e074b8c65908baf95b2b2b0c032f8 389 Pfam PF13439 Glycosyltransferase Family 4 25 180 1.3E-29 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 GBCGDNIH2_RS12595 e0dabedbb35f4050cdfd5b33cf73b440 150 PIRSF PIRSF004638 3 150 3.7E-59 T 29-03-2018 IPR005265 Uncharacterised protein family UPF0093 GBCGDNIH2_RS12595 e0dabedbb35f4050cdfd5b33cf73b440 150 Pfam PF03653 Uncharacterised protein family (UPF0093) 8 150 6.1E-62 T 29-03-2018 IPR005265 Uncharacterised protein family UPF0093 GBCGDNIH2_RS12595 e0dabedbb35f4050cdfd5b33cf73b440 150 TIGRFAM TIGR00701 TIGR00701: TIGR00701 family protein 9 150 1.9E-48 T 29-03-2018 IPR005265 Uncharacterised protein family UPF0093 GBCGDNIH2_RS04215 66f9471957d901b7aa5a2f7acd4395a3 204 Gene3D G3DSA:3.40.50.880 1 192 1.2E-60 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like GBCGDNIH2_RS04215 66f9471957d901b7aa5a2f7acd4395a3 204 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 187 8.1E-66 T 29-03-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 GBCGDNIH2_RS04215 66f9471957d901b7aa5a2f7acd4395a3 204 SUPERFAMILY SSF52317 1 190 2.62E-56 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like GBCGDNIH2_RS04215 66f9471957d901b7aa5a2f7acd4395a3 204 Pfam PF00117 Glutamine amidotransferase class-I 3 187 4.8E-53 T 29-03-2018 IPR017926 Glutamine amidotransferase GBCGDNIH2_RS04215 66f9471957d901b7aa5a2f7acd4395a3 204 PRINTS PR00097 Anthranilate synthase component II signature 100 108 5.0E-34 T 29-03-2018 GBCGDNIH2_RS04215 66f9471957d901b7aa5a2f7acd4395a3 204 PRINTS PR00097 Anthranilate synthase component II signature 2 16 5.0E-34 T 29-03-2018 GBCGDNIH2_RS04215 66f9471957d901b7aa5a2f7acd4395a3 204 PRINTS PR00097 Anthranilate synthase component II signature 120 132 5.0E-34 T 29-03-2018 GBCGDNIH2_RS04215 66f9471957d901b7aa5a2f7acd4395a3 204 PRINTS PR00097 Anthranilate synthase component II signature 47 56 5.0E-34 T 29-03-2018 GBCGDNIH2_RS04215 66f9471957d901b7aa5a2f7acd4395a3 204 PRINTS PR00097 Anthranilate synthase component II signature 75 86 5.0E-34 T 29-03-2018 GBCGDNIH2_RS04215 66f9471957d901b7aa5a2f7acd4395a3 204 PRINTS PR00097 Anthranilate synthase component II signature 165 178 5.0E-34 T 29-03-2018 GBCGDNIH2_RS04215 66f9471957d901b7aa5a2f7acd4395a3 204 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 75 91 3.0E-7 T 29-03-2018 GBCGDNIH2_RS04215 66f9471957d901b7aa5a2f7acd4395a3 204 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 3.0E-7 T 29-03-2018 GBCGDNIH2_RS04215 66f9471957d901b7aa5a2f7acd4395a3 204 PRINTS PR00096 Glutamine amidotransferase superfamily signature 75 86 6.9E-13 T 29-03-2018 GBCGDNIH2_RS04215 66f9471957d901b7aa5a2f7acd4395a3 204 PRINTS PR00096 Glutamine amidotransferase superfamily signature 165 178 6.9E-13 T 29-03-2018 GBCGDNIH2_RS04215 66f9471957d901b7aa5a2f7acd4395a3 204 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 6.9E-13 T 29-03-2018 GBCGDNIH2_RS12430 fbfcac4893eaa35ee3a34318ca5b784c 678 Pfam PF01594 AI-2E family transporter 218 413 1.5E-36 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like GBCGDNIH2_RS12430 fbfcac4893eaa35ee3a34318ca5b784c 678 Pfam PF01594 AI-2E family transporter 39 125 1.4E-10 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like GBCGDNIH2_RS06815 83d55eac119672a8f1c48eb2b8879ff7 261 SMART SM00382 43 223 3.2E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS06815 83d55eac119672a8f1c48eb2b8879ff7 261 SUPERFAMILY SSF52540 15 247 3.77E-66 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS06815 83d55eac119672a8f1c48eb2b8879ff7 261 Gene3D G3DSA:3.40.50.300 13 227 2.5E-56 T 29-03-2018 GBCGDNIH2_RS06815 83d55eac119672a8f1c48eb2b8879ff7 261 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GBCGDNIH2_RS06815 83d55eac119672a8f1c48eb2b8879ff7 261 Pfam PF00005 ABC transporter 34 172 3.2E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GBCGDNIH2_RS11220 c26520bc735662ec5e57a226a0aaa3c5 625 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 18 423 6.0E-175 T 29-03-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 GBCGDNIH2_RS11220 c26520bc735662ec5e57a226a0aaa3c5 625 Gene3D G3DSA:2.40.30.10 217 318 3.9E-25 T 29-03-2018 GBCGDNIH2_RS11220 c26520bc735662ec5e57a226a0aaa3c5 625 Pfam PF00009 Elongation factor Tu GTP binding domain 19 216 4.2E-37 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GBCGDNIH2_RS11220 c26520bc735662ec5e57a226a0aaa3c5 625 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 450 622 37.626 T 29-03-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 GBCGDNIH2_RS11220 c26520bc735662ec5e57a226a0aaa3c5 625 SUPERFAMILY SSF50447 231 319 3.33E-21 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain GBCGDNIH2_RS11220 c26520bc735662ec5e57a226a0aaa3c5 625 SUPERFAMILY SSF52540 446 620 1.09E-36 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS11220 c26520bc735662ec5e57a226a0aaa3c5 625 SUPERFAMILY SSF50465 323 424 1.63E-29 T 29-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal GBCGDNIH2_RS11220 c26520bc735662ec5e57a226a0aaa3c5 625 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 73 88 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site GBCGDNIH2_RS11220 c26520bc735662ec5e57a226a0aaa3c5 625 SUPERFAMILY SSF52540 16 226 8.99E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS11220 c26520bc735662ec5e57a226a0aaa3c5 625 PRINTS PR00315 GTP-binding elongation factor signature 19 32 4.8E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GBCGDNIH2_RS11220 c26520bc735662ec5e57a226a0aaa3c5 625 PRINTS PR00315 GTP-binding elongation factor signature 153 162 4.8E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GBCGDNIH2_RS11220 c26520bc735662ec5e57a226a0aaa3c5 625 PRINTS PR00315 GTP-binding elongation factor signature 80 88 4.8E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GBCGDNIH2_RS11220 c26520bc735662ec5e57a226a0aaa3c5 625 PRINTS PR00315 GTP-binding elongation factor signature 116 127 4.8E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GBCGDNIH2_RS11220 c26520bc735662ec5e57a226a0aaa3c5 625 PRINTS PR00315 GTP-binding elongation factor signature 100 110 4.8E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GBCGDNIH2_RS11220 c26520bc735662ec5e57a226a0aaa3c5 625 Hamap MF_00062 Sulfate adenylyltransferase subunit 1 [cysN]. 9 451 46.289 T 29-03-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 GBCGDNIH2_RS11220 c26520bc735662ec5e57a226a0aaa3c5 625 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 434 615 2.8E-72 T 29-03-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 GBCGDNIH2_RS11220 c26520bc735662ec5e57a226a0aaa3c5 625 Gene3D G3DSA:2.40.30.10 320 425 3.3E-23 T 29-03-2018 GBCGDNIH2_RS11220 c26520bc735662ec5e57a226a0aaa3c5 625 Pfam PF01583 Adenylylsulphate kinase 452 602 2.4E-69 T 29-03-2018 GBCGDNIH2_RS11220 c26520bc735662ec5e57a226a0aaa3c5 625 Gene3D G3DSA:3.40.50.300 448 625 5.7E-47 T 29-03-2018 GBCGDNIH2_RS11220 c26520bc735662ec5e57a226a0aaa3c5 625 Gene3D G3DSA:3.40.50.300 7 216 2.2E-38 T 29-03-2018 GBCGDNIH2_RS03385 8cef556c87333c49f9dae33649eceddb 131 Gene3D G3DSA:3.30.420.180 1 126 6.7E-26 T 29-03-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 GBCGDNIH2_RS03385 8cef556c87333c49f9dae33649eceddb 131 Pfam PF01890 Cobalamin synthesis G C-terminus 7 122 1.0E-17 T 29-03-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 GBCGDNIH2_RS03385 8cef556c87333c49f9dae33649eceddb 131 SUPERFAMILY SSF159664 5 124 2.35E-25 T 29-03-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 GBCGDNIH2_RS00465 00f88513f252aedc808a7160cc0f5aac 171 Gene3D G3DSA:1.20.1260.10 2 170 1.4E-23 T 29-03-2018 IPR012347 Ferritin-related GBCGDNIH2_RS00465 00f88513f252aedc808a7160cc0f5aac 171 Pfam PF05974 Domain of unknown function (DUF892) 7 160 2.3E-40 T 29-03-2018 IPR010287 Domain of unknown function DUF892 GBCGDNIH2_RS00465 00f88513f252aedc808a7160cc0f5aac 171 SUPERFAMILY SSF47240 4 153 1.18E-38 T 29-03-2018 IPR009078 Ferritin-like superfamily GBCGDNIH2_RS12600 ecd5af06b64e3590263d9fe9d28d2a3c 230 Gene3D G3DSA:1.10.150.240 32 78 5.7E-14 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 GBCGDNIH2_RS12600 ecd5af06b64e3590263d9fe9d28d2a3c 230 Pfam PF13419 Haloacid dehalogenase-like hydrolase 9 190 3.8E-18 T 29-03-2018 IPR023214 HAD-like domain GBCGDNIH2_RS12600 ecd5af06b64e3590263d9fe9d28d2a3c 230 SUPERFAMILY SSF56784 6 214 6.48E-42 T 29-03-2018 IPR023214 HAD-like domain GBCGDNIH2_RS12600 ecd5af06b64e3590263d9fe9d28d2a3c 230 Gene3D G3DSA:3.40.50.1000 79 227 7.6E-23 T 29-03-2018 IPR023214 HAD-like domain GBCGDNIH2_RS12600 ecd5af06b64e3590263d9fe9d28d2a3c 230 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 146 190 1.1E-10 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 GBCGDNIH2_RS12600 ecd5af06b64e3590263d9fe9d28d2a3c 230 Gene3D G3DSA:3.40.50.1000 2 31 0.062 T 29-03-2018 IPR023214 HAD-like domain GBCGDNIH2_RS08005 e9bb14291f8a32bd960388429928c8c7 387 Pfam PF13356 Arm DNA-binding domain 4 85 5.1E-15 T 29-03-2018 IPR025166 Integrase, DNA-binding domain GBCGDNIH2_RS08005 e9bb14291f8a32bd960388429928c8c7 387 Pfam PF00589 Phage integrase family 205 359 7.8E-17 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 GBCGDNIH2_RS08005 e9bb14291f8a32bd960388429928c8c7 387 Gene3D G3DSA:1.10.443.10 201 371 2.1E-22 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 GBCGDNIH2_RS08005 e9bb14291f8a32bd960388429928c8c7 387 SUPERFAMILY SSF56349 90 371 5.0E-51 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 GBCGDNIH2_RS08005 e9bb14291f8a32bd960388429928c8c7 387 Gene3D G3DSA:1.10.150.130 80 200 2.3E-16 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal GBCGDNIH2_RS08505 c802a659f183c1bca275ed28b6fbe083 455 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 270 283 - T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 GBCGDNIH2_RS08505 c802a659f183c1bca275ed28b6fbe083 455 SMART SM00963 1 86 1.9E-32 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 GBCGDNIH2_RS08505 c802a659f183c1bca275ed28b6fbe083 455 SUPERFAMILY SSF47446 328 431 3.11E-36 T 29-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 GBCGDNIH2_RS08505 c802a659f183c1bca275ed28b6fbe083 455 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 1.1E-19 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 GBCGDNIH2_RS08505 c802a659f183c1bca275ed28b6fbe083 455 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 448 33.197 T 29-03-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 GBCGDNIH2_RS08505 c802a659f183c1bca275ed28b6fbe083 455 Gene3D G3DSA:1.20.120.140 212 311 5.6E-32 T 29-03-2018 GBCGDNIH2_RS08505 c802a659f183c1bca275ed28b6fbe083 455 SMART SM00382 100 247 1.4E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS08505 c802a659f183c1bca275ed28b6fbe083 455 SMART SM00962 101 297 5.9E-107 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 GBCGDNIH2_RS08505 c802a659f183c1bca275ed28b6fbe083 455 Gene3D G3DSA:3.40.50.300 102 211 1.8E-5 T 29-03-2018 GBCGDNIH2_RS08505 c802a659f183c1bca275ed28b6fbe083 455 Gene3D G3DSA:1.10.260.30 328 433 2.6E-37 T 29-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 GBCGDNIH2_RS08505 c802a659f183c1bca275ed28b6fbe083 455 Pfam PF02978 Signal peptide binding domain 329 428 8.8E-32 T 29-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 GBCGDNIH2_RS08505 c802a659f183c1bca275ed28b6fbe083 455 SUPERFAMILY SSF52540 42 355 1.17E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS08505 c802a659f183c1bca275ed28b6fbe083 455 Pfam PF00448 SRP54-type protein, GTPase domain 104 297 6.7E-68 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 GBCGDNIH2_RS08505 c802a659f183c1bca275ed28b6fbe083 455 Gene3D G3DSA:1.20.120.140 1 91 3.1E-26 T 29-03-2018 GBCGDNIH2_RS08505 c802a659f183c1bca275ed28b6fbe083 455 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 430 1.5E-178 T 29-03-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 GBCGDNIH2_RS03870 3d20de75689541056a3e69a9ac8c6916 1111 TIGRFAM TIGR02456 treS_nterm: trehalose synthase 15 554 1.5E-282 T 29-03-2018 IPR012810 Trehalose synthase/alpha-amylase, N-terminal GO:0003824|GO:0005975 KEGG: 00500+5.4.99.16|MetaCyc: PWY-2622 GBCGDNIH2_RS03870 3d20de75689541056a3e69a9ac8c6916 1111 Gene3D G3DSA:3.90.1200.10 851 1079 3.9E-14 T 29-03-2018 GBCGDNIH2_RS03870 3d20de75689541056a3e69a9ac8c6916 1111 Pfam PF00128 Alpha amylase, catalytic domain 38 391 5.8E-72 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 GBCGDNIH2_RS03870 3d20de75689541056a3e69a9ac8c6916 1111 Gene3D G3DSA:3.20.20.80 20 469 2.7E-122 T 29-03-2018 GBCGDNIH2_RS03870 3d20de75689541056a3e69a9ac8c6916 1111 SUPERFAMILY SSF51011 474 554 2.8E-18 T 29-03-2018 GBCGDNIH2_RS03870 3d20de75689541056a3e69a9ac8c6916 1111 Pfam PF16657 Maltogenic Amylase, C-terminal domain 470 551 9.0E-31 T 29-03-2018 IPR032091 Maltogenic Amylase, C-terminal GBCGDNIH2_RS03870 3d20de75689541056a3e69a9ac8c6916 1111 SUPERFAMILY SSF56112 727 829 6.46E-13 T 29-03-2018 IPR011009 Protein kinase-like domain GBCGDNIH2_RS03870 3d20de75689541056a3e69a9ac8c6916 1111 SUPERFAMILY SSF56112 858 1000 6.46E-13 T 29-03-2018 IPR011009 Protein kinase-like domain GBCGDNIH2_RS03870 3d20de75689541056a3e69a9ac8c6916 1111 SUPERFAMILY SSF56112 1028 1046 6.46E-13 T 29-03-2018 IPR011009 Protein kinase-like domain GBCGDNIH2_RS03870 3d20de75689541056a3e69a9ac8c6916 1111 SMART SM00642 23 417 1.4E-103 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 GBCGDNIH2_RS03870 3d20de75689541056a3e69a9ac8c6916 1111 Gene3D G3DSA:2.60.40.1180 471 559 4.7E-27 T 29-03-2018 GBCGDNIH2_RS03870 3d20de75689541056a3e69a9ac8c6916 1111 SUPERFAMILY SSF51445 13 333 3.96E-131 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily GBCGDNIH2_RS03870 3d20de75689541056a3e69a9ac8c6916 1111 SUPERFAMILY SSF51445 360 467 3.96E-131 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily GBCGDNIH2_RS03870 3d20de75689541056a3e69a9ac8c6916 1111 TIGRFAM TIGR02457 TreS_Cterm: putative maltokinase 571 1095 3.2E-177 T 29-03-2018 IPR012811 Trehalose synthase/probable maltokinase, C-terminal domain GBCGDNIH2_RS10825 a1daa16a7648942a287d31bcca29d0c3 132 TIGRFAM TIGR02968 succ_dehyd_anc: succinate dehydrogenase, hydrophobic membrane anchor protein 24 127 3.6E-23 T 29-03-2018 IPR014312 Succinate dehydrogenase, hydrophobic membrane anchor GO:0000104|GO:0006099|GO:0016021|GO:0020037 GBCGDNIH2_RS10825 a1daa16a7648942a287d31bcca29d0c3 132 Gene3D G3DSA:1.20.1300.10 22 131 4.9E-20 T 29-03-2018 GBCGDNIH2_RS10825 a1daa16a7648942a287d31bcca29d0c3 132 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 14 118 1.8E-17 T 29-03-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 GBCGDNIH2_RS10825 a1daa16a7648942a287d31bcca29d0c3 132 SUPERFAMILY SSF81343 19 129 1.55E-25 T 29-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 GBCGDNIH2_RS08695 0ccb25f45b3fdc4c1ece5e9b3c14f84e 113 Pfam PF09361 Phasin protein 7 105 1.3E-20 T 29-03-2018 IPR018968 Phasin GBCGDNIH2_RS08695 0ccb25f45b3fdc4c1ece5e9b3c14f84e 113 TIGRFAM TIGR01841 phasin: phasin family protein 27 112 6.1E-12 T 29-03-2018 IPR010127 Phasin, subfamily 1 GBCGDNIH2_RS01260 1dc3cd8d66d446ea33933eb9d0a0c3e0 404 Pfam PF03739 Predicted permease YjgP/YjgQ family 44 387 1.9E-55 T 29-03-2018 IPR005495 Permease LptG/LptF-related GO:0016021 GBCGDNIH2_RS01260 1dc3cd8d66d446ea33933eb9d0a0c3e0 404 TIGRFAM TIGR04407 LptF_YjgP: LPS export ABC transporter permease LptF 40 387 5.1E-80 T 29-03-2018 IPR030922 LPS export ABC transporter permease LptF GO:0043190|GO:0055085 GBCGDNIH2_RS04235 a09c69fd03813e3f5a9a8f6a1ab779e6 656 SUPERFAMILY SSF54534 238 368 9.16E-9 T 29-03-2018 GBCGDNIH2_RS04235 a09c69fd03813e3f5a9a8f6a1ab779e6 656 Gene3D G3DSA:1.10.4030.10 48 184 3.8E-17 T 29-03-2018 GBCGDNIH2_RS04235 a09c69fd03813e3f5a9a8f6a1ab779e6 656 Pfam PF13624 SurA N-terminal domain 14 179 9.9E-40 T 29-03-2018 GBCGDNIH2_RS04235 a09c69fd03813e3f5a9a8f6a1ab779e6 656 Gene3D G3DSA:3.10.50.40 524 630 8.3E-5 T 29-03-2018 GBCGDNIH2_RS04235 a09c69fd03813e3f5a9a8f6a1ab779e6 656 Gene3D G3DSA:3.10.50.40 273 396 2.8E-17 T 29-03-2018 GBCGDNIH2_RS04235 a09c69fd03813e3f5a9a8f6a1ab779e6 656 Gene3D G3DSA:3.10.50.40 405 523 6.2E-7 T 29-03-2018 GBCGDNIH2_RS04235 a09c69fd03813e3f5a9a8f6a1ab779e6 656 SUPERFAMILY SSF109998 54 182 3.92E-29 T 29-03-2018 IPR027304 Trigger factor/SurA domain GBCGDNIH2_RS04235 a09c69fd03813e3f5a9a8f6a1ab779e6 656 SUPERFAMILY SSF109998 256 307 3.92E-29 T 29-03-2018 IPR027304 Trigger factor/SurA domain GBCGDNIH2_RS04235 a09c69fd03813e3f5a9a8f6a1ab779e6 656 Pfam PF13145 PPIC-type PPIASE domain 262 384 8.8E-21 T 29-03-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 GBCGDNIH2_RS06270 cc4a6ed082666ef3b6923a54002dd187 139 Pfam PF14832 Putative oxalocrotonate tautomerase enzyme 1 135 2.4E-52 T 29-03-2018 IPR028116 Putative oxalocrotonate tautomerase GBCGDNIH2_RS06270 cc4a6ed082666ef3b6923a54002dd187 139 Gene3D G3DSA:3.30.429.10 1 139 3.8E-36 T 29-03-2018 GBCGDNIH2_RS09535 ede4cd25dd4f69313566ae8117b0360b 260 SMART SM00014 124 234 2.9E-7 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase GBCGDNIH2_RS09535 ede4cd25dd4f69313566ae8117b0360b 260 SUPERFAMILY SSF48317 51 251 1.44E-33 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase GBCGDNIH2_RS09535 ede4cd25dd4f69313566ae8117b0360b 260 Gene3D G3DSA:1.20.144.10 36 255 3.6E-35 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase GBCGDNIH2_RS09535 ede4cd25dd4f69313566ae8117b0360b 260 PIRSF PIRSF000897 17 260 2.3E-53 T 29-03-2018 IPR011158 Nonspecific acid phosphatase, class A GO:0003993|GO:0030288 KEGG: 00740+3.1.3.2|MetaCyc: PWY-6348 GBCGDNIH2_RS09535 ede4cd25dd4f69313566ae8117b0360b 260 Pfam PF01569 PAP2 superfamily 144 229 6.1E-17 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase GBCGDNIH2_RS03835 fe60cca2c969c0bcf220c14b3acb9737 1381 Gene3D G3DSA:3.40.50.2000 547 746 1.9E-26 T 29-03-2018 GBCGDNIH2_RS03835 fe60cca2c969c0bcf220c14b3acb9737 1381 SUPERFAMILY SSF53448 126 355 8.44E-46 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS03835 fe60cca2c969c0bcf220c14b3acb9737 1381 SUPERFAMILY SSF53448 1079 1347 4.19E-54 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS03835 fe60cca2c969c0bcf220c14b3acb9737 1381 Gene3D G3DSA:3.90.550.10 67 392 8.5E-42 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS03835 fe60cca2c969c0bcf220c14b3acb9737 1381 Gene3D G3DSA:3.90.550.10 1055 1364 2.6E-47 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS03835 fe60cca2c969c0bcf220c14b3acb9737 1381 Pfam PF00535 Glycosyl transferase family 2 1098 1278 3.7E-25 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 GBCGDNIH2_RS03835 fe60cca2c969c0bcf220c14b3acb9737 1381 SUPERFAMILY SSF53756 398 757 2.04E-27 T 29-03-2018 GBCGDNIH2_RS03835 fe60cca2c969c0bcf220c14b3acb9737 1381 Pfam PF13641 Glycosyltransferase like family 2 133 368 4.2E-15 T 29-03-2018 GBCGDNIH2_RS03835 fe60cca2c969c0bcf220c14b3acb9737 1381 Pfam PF13692 Glycosyl transferases group 1 589 726 5.2E-24 T 29-03-2018 GBCGDNIH2_RS11850 d332b57fbd5588e234d9e4ef9031a9f5 1092 SUPERFAMILY SSF48108 403 553 7.45E-45 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 GBCGDNIH2_RS11850 d332b57fbd5588e234d9e4ef9031a9f5 1092 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 334 5.1E-68 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 GBCGDNIH2_RS11850 d332b57fbd5588e234d9e4ef9031a9f5 1092 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 686 893 1.1E-32 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 GBCGDNIH2_RS11850 d332b57fbd5588e234d9e4ef9031a9f5 1092 Pfam PF02142 MGS-like domain 974 1059 6.8E-19 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain GBCGDNIH2_RS11850 d332b57fbd5588e234d9e4ef9031a9f5 1092 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 3.8E-64 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 GBCGDNIH2_RS11850 d332b57fbd5588e234d9e4ef9031a9f5 1092 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 3.8E-64 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 GBCGDNIH2_RS11850 d332b57fbd5588e234d9e4ef9031a9f5 1092 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 297 326 3.8E-64 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 GBCGDNIH2_RS11850 d332b57fbd5588e234d9e4ef9031a9f5 1092 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 3.8E-64 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 GBCGDNIH2_RS11850 d332b57fbd5588e234d9e4ef9031a9f5 1092 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 387 405 3.8E-64 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 GBCGDNIH2_RS11850 d332b57fbd5588e234d9e4ef9031a9f5 1092 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 3.8E-64 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 GBCGDNIH2_RS11850 d332b57fbd5588e234d9e4ef9031a9f5 1092 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 3.8E-64 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 GBCGDNIH2_RS11850 d332b57fbd5588e234d9e4ef9031a9f5 1092 SMART SM00851 973 1059 7.4E-32 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain GBCGDNIH2_RS11850 d332b57fbd5588e234d9e4ef9031a9f5 1092 Gene3D G3DSA:3.40.50.20 543 667 7.3E-56 T 29-03-2018 GBCGDNIH2_RS11850 d332b57fbd5588e234d9e4ef9031a9f5 1092 Gene3D G3DSA:3.40.50.1380 953 1092 2.7E-41 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain GBCGDNIH2_RS11850 d332b57fbd5588e234d9e4ef9031a9f5 1092 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1079 13.005 T 29-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 GBCGDNIH2_RS11850 d332b57fbd5588e234d9e4ef9031a9f5 1092 SMART SM01096 429 551 9.2E-65 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 GBCGDNIH2_RS11850 d332b57fbd5588e234d9e4ef9031a9f5 1092 SUPERFAMILY SSF56059 686 951 1.59E-98 T 29-03-2018 GBCGDNIH2_RS11850 d332b57fbd5588e234d9e4ef9031a9f5 1092 Gene3D G3DSA:3.40.50.20 4 117 6.3E-38 T 29-03-2018 GBCGDNIH2_RS11850 d332b57fbd5588e234d9e4ef9031a9f5 1092 SUPERFAMILY SSF52335 953 1089 6.8E-41 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain GBCGDNIH2_RS11850 d332b57fbd5588e234d9e4ef9031a9f5 1092 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 722 736 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 GBCGDNIH2_RS11850 d332b57fbd5588e234d9e4ef9031a9f5 1092 SUPERFAMILY SSF52440 1 127 1.24E-48 T 29-03-2018 IPR016185 Pre-ATP-grasp domain GBCGDNIH2_RS11850 d332b57fbd5588e234d9e4ef9031a9f5 1092 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 297 304 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 GBCGDNIH2_RS11850 d332b57fbd5588e234d9e4ef9031a9f5 1092 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1070 0.0 T 29-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 GBCGDNIH2_RS11850 d332b57fbd5588e234d9e4ef9031a9f5 1092 Gene3D G3DSA:3.30.470.20 119 410 3.4E-63 T 29-03-2018 GBCGDNIH2_RS11850 d332b57fbd5588e234d9e4ef9031a9f5 1092 Gene3D G3DSA:3.30.1490.20 668 756 7.9E-22 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 GBCGDNIH2_RS11850 d332b57fbd5588e234d9e4ef9031a9f5 1092 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 432 551 1.0E-37 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 GBCGDNIH2_RS11850 d332b57fbd5588e234d9e4ef9031a9f5 1092 Gene3D G3DSA:1.10.1030.10 421 542 5.4E-43 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 GBCGDNIH2_RS11850 d332b57fbd5588e234d9e4ef9031a9f5 1092 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 856 863 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 GBCGDNIH2_RS11850 d332b57fbd5588e234d9e4ef9031a9f5 1092 SUPERFAMILY SSF56059 128 408 3.01E-104 T 29-03-2018 GBCGDNIH2_RS11850 d332b57fbd5588e234d9e4ef9031a9f5 1092 SUPERFAMILY SSF52440 565 688 2.88E-45 T 29-03-2018 IPR016185 Pre-ATP-grasp domain GBCGDNIH2_RS11850 d332b57fbd5588e234d9e4ef9031a9f5 1092 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1087 13.293 T 29-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 GBCGDNIH2_RS11850 d332b57fbd5588e234d9e4ef9031a9f5 1092 Gene3D G3DSA:3.30.470.20 757 952 1.2E-38 T 29-03-2018 GBCGDNIH2_RS03880 ca491e048217c1375e33819ddde38d96 247 SUPERFAMILY SSF88659 74 122 4.67E-5 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GBCGDNIH2_RS03880 ca491e048217c1375e33819ddde38d96 247 Gene3D G3DSA:3.40.50.2300 124 245 5.9E-22 T 29-03-2018 GBCGDNIH2_RS03880 ca491e048217c1375e33819ddde38d96 247 SUPERFAMILY SSF52172 126 240 3.56E-24 T 29-03-2018 IPR011006 CheY-like superfamily GBCGDNIH2_RS03880 ca491e048217c1375e33819ddde38d96 247 Pfam PF00072 Response regulator receiver domain 128 232 2.1E-15 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GBCGDNIH2_RS03880 ca491e048217c1375e33819ddde38d96 247 SMART SM00448 126 236 3.9E-17 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GBCGDNIH2_RS03880 ca491e048217c1375e33819ddde38d96 247 Gene3D G3DSA:1.10.10.10 5 123 6.4E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS12205 a2e7aea4035d203d5a656540ad0776e6 327 Gene3D G3DSA:3.90.25.10 245 326 5.4E-23 T 29-03-2018 GBCGDNIH2_RS12205 a2e7aea4035d203d5a656540ad0776e6 327 Gene3D G3DSA:3.90.25.10 200 244 4.9E-24 T 29-03-2018 GBCGDNIH2_RS12205 a2e7aea4035d203d5a656540ad0776e6 327 Hamap MF_00955 GDP-mannose 4,6-dehydratase [gmd]. 2 323 51.461 T 29-03-2018 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 GBCGDNIH2_RS12205 a2e7aea4035d203d5a656540ad0776e6 327 Pfam PF16363 GDP-mannose 4,6 dehydratase 5 313 3.9E-122 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS12205 a2e7aea4035d203d5a656540ad0776e6 327 SUPERFAMILY SSF51735 3 319 8.32E-75 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS12205 a2e7aea4035d203d5a656540ad0776e6 327 Gene3D G3DSA:3.40.50.720 2 199 4.1E-24 T 29-03-2018 GBCGDNIH2_RS12205 a2e7aea4035d203d5a656540ad0776e6 327 TIGRFAM TIGR01472 gmd: GDP-mannose 4,6-dehydratase 3 319 2.8E-126 T 29-03-2018 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 GBCGDNIH2_RS01930 08e916b979dc42b72f405dc7f39c4bfb 144 Pfam PF06262 Zincin-like metallopeptidase 39 133 9.7E-31 T 29-03-2018 IPR010428 Zincin-like metallopeptidase GBCGDNIH2_RS01930 08e916b979dc42b72f405dc7f39c4bfb 144 SUPERFAMILY SSF55486 14 134 4.64E-27 T 29-03-2018 GBCGDNIH2_RS08475 b26942c19bac382772b3c88814c6abde 1265 SUPERFAMILY SSF51126 12 386 1.54E-5 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor GBCGDNIH2_RS08475 b26942c19bac382772b3c88814c6abde 1265 SUPERFAMILY SSF51120 894 1018 2.09E-12 T 29-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal GBCGDNIH2_RS08475 b26942c19bac382772b3c88814c6abde 1265 SUPERFAMILY SSF51120 756 800 2.09E-12 T 29-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal GBCGDNIH2_RS08475 b26942c19bac382772b3c88814c6abde 1265 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 241 277 6.5E-7 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08475 b26942c19bac382772b3c88814c6abde 1265 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 369 406 2.9E-11 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08475 b26942c19bac382772b3c88814c6abde 1265 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 331 368 6.5E-6 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08475 b26942c19bac382772b3c88814c6abde 1265 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 33 68 8.7E-6 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08475 b26942c19bac382772b3c88814c6abde 1265 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 446 482 9.9E-9 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08475 b26942c19bac382772b3c88814c6abde 1265 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 71 106 1.3E-9 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08475 b26942c19bac382772b3c88814c6abde 1265 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 116 144 1.1E-4 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08475 b26942c19bac382772b3c88814c6abde 1265 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 147 182 2.1E-9 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08475 b26942c19bac382772b3c88814c6abde 1265 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 595 629 3.7E-8 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08475 b26942c19bac382772b3c88814c6abde 1265 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 484 519 2.2E-6 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08475 b26942c19bac382772b3c88814c6abde 1265 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 185 220 1.2E-7 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08475 b26942c19bac382772b3c88814c6abde 1265 Pfam PF16168 Adhesin of bacterial autotransporter system, probable stalk 366 417 1.0E-7 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08475 b26942c19bac382772b3c88814c6abde 1265 Pfam PF16168 Adhesin of bacterial autotransporter system, probable stalk 446 493 3.2E-6 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08475 b26942c19bac382772b3c88814c6abde 1265 SUPERFAMILY SSF51120 1090 1257 5.1E-8 T 29-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal GBCGDNIH2_RS08475 b26942c19bac382772b3c88814c6abde 1265 SUPERFAMILY SSF51120 1029 1062 5.1E-8 T 29-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal GBCGDNIH2_RS08475 b26942c19bac382772b3c88814c6abde 1265 Gene3D G3DSA:2.150.10.10 814 1032 3.1E-12 T 29-03-2018 GBCGDNIH2_RS00820 9b885d9e917ba7af0e2447b6714c006d 350 Pfam PF00953 Glycosyl transferase family 4 81 233 3.1E-36 T 29-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 GBCGDNIH2_RS00240 508a118c87fa84e397d7a00bea577ae8 394 SUPERFAMILY SSF53383 3 373 1.43E-100 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase GBCGDNIH2_RS00240 508a118c87fa84e397d7a00bea577ae8 394 PIRSF PIRSF000524 1 394 1.0E-127 T 29-03-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661 GBCGDNIH2_RS00240 508a118c87fa84e397d7a00bea577ae8 394 Gene3D G3DSA:3.40.640.10 13 275 2.4E-42 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GBCGDNIH2_RS00240 508a118c87fa84e397d7a00bea577ae8 394 Gene3D G3DSA:3.90.1150.10 276 394 7.2E-34 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 GBCGDNIH2_RS00240 508a118c87fa84e397d7a00bea577ae8 394 Pfam PF00266 Aminotransferase class-V 7 339 9.8E-36 T 29-03-2018 IPR000192 Aminotransferase class V domain GBCGDNIH2_RS00240 508a118c87fa84e397d7a00bea577ae8 394 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 187 207 - T 29-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site GBCGDNIH2_RS01050 c9acae0eba708463ba17b3c134f3a9b8 735 Gene3D G3DSA:1.10.486.10 385 547 2.8E-43 T 29-03-2018 GBCGDNIH2_RS01050 c9acae0eba708463ba17b3c134f3a9b8 735 Gene3D G3DSA:3.40.50.300 137 281 1.9E-34 T 29-03-2018 GBCGDNIH2_RS01050 c9acae0eba708463ba17b3c134f3a9b8 735 Gene3D G3DSA:3.40.50.300 1 133 3.7E-29 T 29-03-2018 GBCGDNIH2_RS01050 c9acae0eba708463ba17b3c134f3a9b8 735 Gene3D G3DSA:3.40.50.300 282 384 7.7E-22 T 29-03-2018 GBCGDNIH2_RS01050 c9acae0eba708463ba17b3c134f3a9b8 735 Pfam PF00580 UvrD/REP helicase N-terminal domain 4 272 8.3E-77 T 29-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 GBCGDNIH2_RS01050 c9acae0eba708463ba17b3c134f3a9b8 735 SUPERFAMILY SSF52540 2 636 7.63E-170 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS01050 c9acae0eba708463ba17b3c134f3a9b8 735 Pfam PF13361 UvrD-like helicase C-terminal domain 277 609 1.7E-55 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 GBCGDNIH2_RS01630 5b61720c3c5e0d1ede172b972f14bf2b 852 SUPERFAMILY SSF52540 143 391 5.32E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS01630 5b61720c3c5e0d1ede172b972f14bf2b 852 SMART SM00490 178 267 1.4E-12 T 29-03-2018 IPR001650 Helicase, C-terminal GBCGDNIH2_RS01630 5b61720c3c5e0d1ede172b972f14bf2b 852 Gene3D G3DSA:3.40.50.300 151 290 2.4E-16 T 29-03-2018 GBCGDNIH2_RS01630 5b61720c3c5e0d1ede172b972f14bf2b 852 SUPERFAMILY SSF52540 11 116 7.34E-6 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS01630 5b61720c3c5e0d1ede172b972f14bf2b 852 Pfam PF00271 Helicase conserved C-terminal domain 177 266 2.2E-7 T 29-03-2018 IPR001650 Helicase, C-terminal GBCGDNIH2_RS12000 99f4b51b82252a4b49d28be65b4999fc 364 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 364 5.3E-148 T 29-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 GBCGDNIH2_RS12000 99f4b51b82252a4b49d28be65b4999fc 364 Gene3D G3DSA:1.10.150.300 111 200 1.9E-25 T 29-03-2018 IPR023192 TGS-like domain Reactome: R-HSA-114608 GBCGDNIH2_RS12000 99f4b51b82252a4b49d28be65b4999fc 364 SUPERFAMILY SSF52540 3 301 1.11E-78 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS12000 99f4b51b82252a4b49d28be65b4999fc 364 PIRSF PIRSF006641 1 364 1.5E-152 T 29-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 GBCGDNIH2_RS12000 99f4b51b82252a4b49d28be65b4999fc 364 Pfam PF01926 50S ribosome-binding GTPase 5 120 3.6E-23 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 GBCGDNIH2_RS12000 99f4b51b82252a4b49d28be65b4999fc 364 Gene3D G3DSA:3.40.50.300 1 81 2.1E-9 T 29-03-2018 GBCGDNIH2_RS12000 99f4b51b82252a4b49d28be65b4999fc 364 SUPERFAMILY SSF81271 280 361 7.85E-36 T 29-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 GBCGDNIH2_RS12000 99f4b51b82252a4b49d28be65b4999fc 364 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 364 43.51 T 29-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 GBCGDNIH2_RS12000 99f4b51b82252a4b49d28be65b4999fc 364 Gene3D G3DSA:3.10.20.30 264 363 1.5E-45 T 29-03-2018 IPR012675 Beta-grasp domain GBCGDNIH2_RS12000 99f4b51b82252a4b49d28be65b4999fc 364 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 8.0E-35 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 GBCGDNIH2_RS12000 99f4b51b82252a4b49d28be65b4999fc 364 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 71 86 8.0E-35 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 GBCGDNIH2_RS12000 99f4b51b82252a4b49d28be65b4999fc 364 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 88 106 8.0E-35 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 GBCGDNIH2_RS12000 99f4b51b82252a4b49d28be65b4999fc 364 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 27 45 8.0E-35 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 GBCGDNIH2_RS12000 99f4b51b82252a4b49d28be65b4999fc 364 Pfam PF06071 Protein of unknown function (DUF933) 280 363 2.8E-39 T 29-03-2018 IPR013029 Domain of unknown function DUF933 Reactome: R-HSA-114608 GBCGDNIH2_RS03710 3ec0ef535f496b74cf4ce152f6ed0819 90 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 14 76 6.7E-25 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor GBCGDNIH2_RS03710 3ec0ef535f496b74cf4ce152f6ed0819 90 SMART SM01234 7 74 2.6E-35 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor GBCGDNIH2_RS03710 3ec0ef535f496b74cf4ce152f6ed0819 90 Pfam PF01809 Haemolytic domain 12 74 9.2E-27 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor GBCGDNIH2_RS03710 3ec0ef535f496b74cf4ce152f6ed0819 90 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 7 75 22.755 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor GBCGDNIH2_RS03710 3ec0ef535f496b74cf4ce152f6ed0819 90 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 22 74 3.0E-15 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor GBCGDNIH2_RS09835 e0bcb1ca5311199bd1a3313a51eb1c62 288 Pfam PF13242 HAD-hyrolase-like 202 260 5.7E-14 T 29-03-2018 GBCGDNIH2_RS09835 e0bcb1ca5311199bd1a3313a51eb1c62 288 TIGRFAM TIGR01459 HAD-SF-IIA-hyp4: HAD hydrolase, TIGR01459 family 8 250 7.2E-56 T 29-03-2018 IPR006356 HAD-superfamily hydrolase, subfamily IIA, hypothetical 3 GBCGDNIH2_RS09835 e0bcb1ca5311199bd1a3313a51eb1c62 288 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 18 251 1.8E-37 T 29-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA GBCGDNIH2_RS09835 e0bcb1ca5311199bd1a3313a51eb1c62 288 Gene3D G3DSA:3.40.50.1000 9 287 1.0E-33 T 29-03-2018 IPR023214 HAD-like domain GBCGDNIH2_RS09835 e0bcb1ca5311199bd1a3313a51eb1c62 288 SUPERFAMILY SSF56784 14 261 3.69E-48 T 29-03-2018 IPR023214 HAD-like domain GBCGDNIH2_RS09835 e0bcb1ca5311199bd1a3313a51eb1c62 288 Pfam PF13344 Haloacid dehalogenase-like hydrolase 18 123 1.4E-17 T 29-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA GBCGDNIH2_RS11100 79050e4772b9fd050b58c259e73026d1 158 SMART SM00347 25 126 5.8E-20 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GBCGDNIH2_RS11100 79050e4772b9fd050b58c259e73026d1 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 67 82 4.1E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GBCGDNIH2_RS11100 79050e4772b9fd050b58c259e73026d1 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 102 4.1E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GBCGDNIH2_RS11100 79050e4772b9fd050b58c259e73026d1 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 50 66 4.1E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GBCGDNIH2_RS11100 79050e4772b9fd050b58c259e73026d1 158 SUPERFAMILY SSF46785 7 143 6.76E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS11100 79050e4772b9fd050b58c259e73026d1 158 ProSitePatterns PS01117 MarR-type HTH domain signature. 65 99 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site GBCGDNIH2_RS11100 79050e4772b9fd050b58c259e73026d1 158 Gene3D G3DSA:1.10.10.10 2 144 2.5E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS11100 79050e4772b9fd050b58c259e73026d1 158 Pfam PF12802 MarR family 31 90 4.5E-11 T 29-03-2018 GBCGDNIH2_RS09855 01073a97cab143d3a7169219d4e9867f 322 Gene3D G3DSA:3.40.30.10 28 179 3.6E-33 T 29-03-2018 GBCGDNIH2_RS09855 01073a97cab143d3a7169219d4e9867f 322 SUPERFAMILY SSF47616 168 315 2.92E-34 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like GBCGDNIH2_RS09855 01073a97cab143d3a7169219d4e9867f 322 PIRSF PIRSF015753 5 315 1.4E-132 T 29-03-2018 IPR016639 Glutathione S-transferase (GST) KEGG: 00480+2.5.1.18|KEGG: 00980+2.5.1.18|KEGG: 00982+2.5.1.18|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7533 GBCGDNIH2_RS09855 01073a97cab143d3a7169219d4e9867f 322 Pfam PF13410 Glutathione S-transferase, C-terminal domain 195 267 1.4E-13 T 29-03-2018 GBCGDNIH2_RS09855 01073a97cab143d3a7169219d4e9867f 322 SUPERFAMILY SSF52833 31 153 1.04E-15 T 29-03-2018 IPR012336 Thioredoxin-like fold GBCGDNIH2_RS09855 01073a97cab143d3a7169219d4e9867f 322 Gene3D G3DSA:1.20.1050.10 180 318 1.1E-40 T 29-03-2018 GBCGDNIH2_RS09855 01073a97cab143d3a7169219d4e9867f 322 Pfam PF13409 Glutathione S-transferase, N-terminal domain 54 149 2.3E-22 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 GBCGDNIH2_RS00565 94b464b18e167cd351c0471e7952edcb 65 Pfam PF04324 BFD-like [2Fe-2S] binding domain 2 49 2.3E-5 T 29-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain GBCGDNIH2_RS00705 dd92813b83d13336ccccaaf24fb66c44 295 SUPERFAMILY SSF51735 10 175 5.79E-49 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS00705 dd92813b83d13336ccccaaf24fb66c44 295 SUPERFAMILY SSF48179 180 290 9.52E-34 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 GBCGDNIH2_RS00705 dd92813b83d13336ccccaaf24fb66c44 295 Pfam PF02153 Prephenate dehydrogenase 23 277 4.0E-76 T 29-03-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 GBCGDNIH2_RS00705 dd92813b83d13336ccccaaf24fb66c44 295 Gene3D G3DSA:3.40.50.720 8 177 3.4E-35 T 29-03-2018 GBCGDNIH2_RS00705 dd92813b83d13336ccccaaf24fb66c44 295 Gene3D G3DSA:1.10.3660.10 187 295 1.6E-31 T 29-03-2018 GBCGDNIH2_RS09620 10e782e18b8b17bc3ff5086818f3f602 306 Gene3D G3DSA:3.40.50.2300 3 249 5.2E-36 T 29-03-2018 GBCGDNIH2_RS09620 10e782e18b8b17bc3ff5086818f3f602 306 SUPERFAMILY SSF52172 7 137 3.98E-39 T 29-03-2018 IPR011006 CheY-like superfamily GBCGDNIH2_RS09620 10e782e18b8b17bc3ff5086818f3f602 306 Pfam PF00196 Bacterial regulatory proteins, luxR family 246 298 4.8E-17 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 GBCGDNIH2_RS09620 10e782e18b8b17bc3ff5086818f3f602 306 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 259 275 1.5E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 GBCGDNIH2_RS09620 10e782e18b8b17bc3ff5086818f3f602 306 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 245 259 1.5E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 GBCGDNIH2_RS09620 10e782e18b8b17bc3ff5086818f3f602 306 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 275 287 1.5E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 GBCGDNIH2_RS09620 10e782e18b8b17bc3ff5086818f3f602 306 Pfam PF00072 Response regulator receiver domain 7 118 1.1E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GBCGDNIH2_RS09620 10e782e18b8b17bc3ff5086818f3f602 306 Gene3D G3DSA:1.10.10.10 250 303 2.0E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS09620 10e782e18b8b17bc3ff5086818f3f602 306 SUPERFAMILY SSF46894 230 301 2.11E-17 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 GBCGDNIH2_RS09620 10e782e18b8b17bc3ff5086818f3f602 306 SMART SM00448 5 118 8.9E-36 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GBCGDNIH2_RS09620 10e782e18b8b17bc3ff5086818f3f602 306 SMART SM00421 242 299 1.3E-19 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 GBCGDNIH2_RS08065 dbc9f35c1509255e9b1e41dccb88fc4a 399 SMART SM00974 283 377 9.7E-21 T 29-03-2018 IPR018306 Bacteriophage T5, Orf172 DNA-binding GBCGDNIH2_RS08065 dbc9f35c1509255e9b1e41dccb88fc4a 399 Pfam PF10544 T5orf172 domain 267 378 3.2E-11 T 29-03-2018 IPR018306 Bacteriophage T5, Orf172 DNA-binding GBCGDNIH2_RS02200 09b216ee6e934ec6e4d163b50e02e113 309 Gene3D G3DSA:3.30.43.10 15 90 5.6E-18 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 GBCGDNIH2_RS02200 09b216ee6e934ec6e4d163b50e02e113 309 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 200 297 3.0E-28 T 29-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GBCGDNIH2_RS02200 09b216ee6e934ec6e4d163b50e02e113 309 Gene3D G3DSA:3.90.78.10 201 298 1.0E-27 T 29-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GBCGDNIH2_RS02200 09b216ee6e934ec6e4d163b50e02e113 309 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 25 299 2.6E-49 T 29-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GBCGDNIH2_RS02200 09b216ee6e934ec6e4d163b50e02e113 309 SUPERFAMILY SSF56194 196 300 5.62E-34 T 29-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GBCGDNIH2_RS02200 09b216ee6e934ec6e4d163b50e02e113 309 SUPERFAMILY SSF56176 24 208 4.46E-38 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 GBCGDNIH2_RS02200 09b216ee6e934ec6e4d163b50e02e113 309 Pfam PF01565 FAD binding domain 40 158 4.1E-15 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 GBCGDNIH2_RS02200 09b216ee6e934ec6e4d163b50e02e113 309 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 309 84.85 T 29-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GBCGDNIH2_RS02200 09b216ee6e934ec6e4d163b50e02e113 309 Gene3D G3DSA:3.30.465.10 91 200 4.5E-29 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 GBCGDNIH2_RS09160 8b56bb87b61df579236a0d7a8e3414de 244 TIGRFAM TIGR03425 urea_degr_2: urea carboxylase-associated protein 2 6 236 1.4E-100 T 29-03-2018 IPR017792 Urea carboxylase-associated protein 2 GBCGDNIH2_RS09160 8b56bb87b61df579236a0d7a8e3414de 244 Pfam PF09347 Domain of unknown function (DUF1989) 10 181 6.7E-58 T 29-03-2018 IPR018959 Domain of unknown function DUF1989 GBCGDNIH2_RS05165 34bd4af3c4696261b3acfcb1ea77b4ff 166 Gene3D G3DSA:3.30.420.140 15 162 9.2E-35 T 29-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 GBCGDNIH2_RS05165 34bd4af3c4696261b3acfcb1ea77b4ff 166 SUPERFAMILY SSF53098 17 152 1.52E-32 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 GBCGDNIH2_RS05165 34bd4af3c4696261b3acfcb1ea77b4ff 166 SMART SM00732 17 117 3.1E-16 T 29-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 GBCGDNIH2_RS05165 34bd4af3c4696261b3acfcb1ea77b4ff 166 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 20 150 6.8E-20 T 29-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 GBCGDNIH2_RS05165 34bd4af3c4696261b3acfcb1ea77b4ff 166 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 17 153 20.688 T 29-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 GBCGDNIH2_RS05165 34bd4af3c4696261b3acfcb1ea77b4ff 166 Pfam PF03652 Holliday junction resolvase 18 150 6.4E-34 T 29-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 GBCGDNIH2_RS07645 289cb00ae0c96f25e4bedbde42bd33a3 438 SUPERFAMILY SSF55021 356 426 5.39E-14 T 29-03-2018 GBCGDNIH2_RS07645 289cb00ae0c96f25e4bedbde42bd33a3 438 Gene3D G3DSA:3.40.50.720 7 158 4.9E-33 T 29-03-2018 GBCGDNIH2_RS07645 289cb00ae0c96f25e4bedbde42bd33a3 438 Gene3D G3DSA:3.30.360.10 159 308 2.5E-56 T 29-03-2018 GBCGDNIH2_RS07645 289cb00ae0c96f25e4bedbde42bd33a3 438 Gene3D G3DSA:3.30.70.260 355 434 3.5E-19 T 29-03-2018 GBCGDNIH2_RS07645 289cb00ae0c96f25e4bedbde42bd33a3 438 SUPERFAMILY SSF51735 11 168 1.24E-33 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS07645 289cb00ae0c96f25e4bedbde42bd33a3 438 PIRSF PIRSF000098 10 438 2.7E-157 T 29-03-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 GBCGDNIH2_RS07645 289cb00ae0c96f25e4bedbde42bd33a3 438 Pfam PF01842 ACT domain 358 416 2.3E-11 T 29-03-2018 IPR002912 ACT domain GBCGDNIH2_RS07645 289cb00ae0c96f25e4bedbde42bd33a3 438 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 19 139 1.8E-18 T 29-03-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 GBCGDNIH2_RS07645 289cb00ae0c96f25e4bedbde42bd33a3 438 Pfam PF00742 Homoserine dehydrogenase 147 325 1.9E-63 T 29-03-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 GBCGDNIH2_RS07645 289cb00ae0c96f25e4bedbde42bd33a3 438 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 193 215 - T 29-03-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 GBCGDNIH2_RS07645 289cb00ae0c96f25e4bedbde42bd33a3 438 SUPERFAMILY SSF55347 147 312 1.83E-51 T 29-03-2018 GBCGDNIH2_RS00295 be4fb19eb973d2f0756b7daa67709563 424 Pfam PF07497 Rho termination factor, RNA-binding domain 52 125 1.1E-30 T 29-03-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 GBCGDNIH2_RS00295 be4fb19eb973d2f0756b7daa67709563 424 SUPERFAMILY SSF50249 49 125 4.03E-28 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold GBCGDNIH2_RS00295 be4fb19eb973d2f0756b7daa67709563 424 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 166 369 7.9E-23 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 GBCGDNIH2_RS00295 be4fb19eb973d2f0756b7daa67709563 424 Gene3D G3DSA:3.40.50.300 129 424 9.2E-56 T 29-03-2018 GBCGDNIH2_RS00295 be4fb19eb973d2f0756b7daa67709563 424 SUPERFAMILY SSF68912 1 46 1.37E-11 T 29-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 GBCGDNIH2_RS00295 be4fb19eb973d2f0756b7daa67709563 424 SMART SM00382 176 355 3.5E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS00295 be4fb19eb973d2f0756b7daa67709563 424 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 424 244.579 T 29-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 GBCGDNIH2_RS00295 be4fb19eb973d2f0756b7daa67709563 424 SUPERFAMILY SSF52540 94 377 1.63E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS00295 be4fb19eb973d2f0756b7daa67709563 424 SMART SM00959 5 47 5.2E-17 T 29-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 GBCGDNIH2_RS00295 be4fb19eb973d2f0756b7daa67709563 424 Pfam PF07498 Rho termination factor, N-terminal domain 5 46 3.1E-16 T 29-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 GBCGDNIH2_RS00295 be4fb19eb973d2f0756b7daa67709563 424 TIGRFAM TIGR00767 rho: transcription termination factor Rho 2 423 7.2E-211 T 29-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 GBCGDNIH2_RS00295 be4fb19eb973d2f0756b7daa67709563 424 SMART SM00357 52 118 3.9E-16 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 GBCGDNIH2_RS00295 be4fb19eb973d2f0756b7daa67709563 424 Gene3D G3DSA:2.40.50.140 2 126 4.8E-44 T 29-03-2018 GBCGDNIH2_RS04395 c7faec4d2d7c5ddd78bbd0666db57c7d 698 Gene3D G3DSA:3.40.50.920 566 690 1.3E-35 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 GBCGDNIH2_RS04395 c7faec4d2d7c5ddd78bbd0666db57c7d 698 SUPERFAMILY SSF52518 360 554 1.04E-59 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold GBCGDNIH2_RS04395 c7faec4d2d7c5ddd78bbd0666db57c7d 698 Gene3D G3DSA:3.40.50.970 4 378 9.5E-99 T 29-03-2018 GBCGDNIH2_RS04395 c7faec4d2d7c5ddd78bbd0666db57c7d 698 SUPERFAMILY SSF52518 11 344 1.43E-104 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold GBCGDNIH2_RS04395 c7faec4d2d7c5ddd78bbd0666db57c7d 698 Pfam PF02779 Transketolase, pyrimidine binding domain 373 551 3.1E-37 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain GBCGDNIH2_RS04395 c7faec4d2d7c5ddd78bbd0666db57c7d 698 TIGRFAM TIGR00232 tktlase_bact: transketolase 13 689 1.2E-247 T 29-03-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 GBCGDNIH2_RS04395 c7faec4d2d7c5ddd78bbd0666db57c7d 698 Gene3D G3DSA:3.40.50.970 379 561 7.0E-38 T 29-03-2018 GBCGDNIH2_RS04395 c7faec4d2d7c5ddd78bbd0666db57c7d 698 SMART SM00861 374 552 3.2E-58 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain GBCGDNIH2_RS04395 c7faec4d2d7c5ddd78bbd0666db57c7d 698 ProSitePatterns PS00801 Transketolase signature 1. 18 38 - T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 GBCGDNIH2_RS04395 c7faec4d2d7c5ddd78bbd0666db57c7d 698 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 11 357 1.4E-130 T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 GBCGDNIH2_RS04395 c7faec4d2d7c5ddd78bbd0666db57c7d 698 SUPERFAMILY SSF52922 561 693 2.22E-44 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 GBCGDNIH2_RS04395 c7faec4d2d7c5ddd78bbd0666db57c7d 698 Pfam PF02780 Transketolase, C-terminal domain 574 683 2.8E-12 T 29-03-2018 IPR033248 Transketolase, C-terminal domain GBCGDNIH2_RS07830 59da2de43fa38cd6d28d19e0d741efeb 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 70 93 1.2E-64 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 GBCGDNIH2_RS07830 59da2de43fa38cd6d28d19e0d741efeb 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 50 68 1.2E-64 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 GBCGDNIH2_RS07830 59da2de43fa38cd6d28d19e0d741efeb 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 304 330 1.2E-64 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 GBCGDNIH2_RS07830 59da2de43fa38cd6d28d19e0d741efeb 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 188 208 1.2E-64 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 GBCGDNIH2_RS07830 59da2de43fa38cd6d28d19e0d741efeb 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 133 152 1.2E-64 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 GBCGDNIH2_RS07830 59da2de43fa38cd6d28d19e0d741efeb 347 Gene3D G3DSA:3.90.640.10 196 255 1.1E-24 T 29-03-2018 GBCGDNIH2_RS07830 59da2de43fa38cd6d28d19e0d741efeb 347 Pfam PF06723 MreB/Mbl protein 11 339 1.3E-151 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 GBCGDNIH2_RS07830 59da2de43fa38cd6d28d19e0d741efeb 347 Gene3D G3DSA:3.30.420.40 8 160 1.2E-40 T 29-03-2018 GBCGDNIH2_RS07830 59da2de43fa38cd6d28d19e0d741efeb 347 SUPERFAMILY SSF53067 150 333 2.77E-47 T 29-03-2018 GBCGDNIH2_RS07830 59da2de43fa38cd6d28d19e0d741efeb 347 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 10 340 6.4E-156 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 GBCGDNIH2_RS07830 59da2de43fa38cd6d28d19e0d741efeb 347 Gene3D G3DSA:3.30.420.40 256 321 3.5E-11 T 29-03-2018 GBCGDNIH2_RS07830 59da2de43fa38cd6d28d19e0d741efeb 347 Gene3D G3DSA:3.30.420.40 161 195 7.2E-4 T 29-03-2018 GBCGDNIH2_RS07830 59da2de43fa38cd6d28d19e0d741efeb 347 SUPERFAMILY SSF53067 10 149 1.49E-39 T 29-03-2018 GBCGDNIH2_RS01720 6efb5f2d929a8e10ea21b97e92c8cf8e 387 Pfam PF10129 OpgC protein 8 363 1.8E-114 T 29-03-2018 IPR014550 Uncharacterised conserved protein UCP028704, OpgC GBCGDNIH2_RS01720 6efb5f2d929a8e10ea21b97e92c8cf8e 387 PIRSF PIRSF028704 1 386 2.0E-99 T 29-03-2018 IPR014550 Uncharacterised conserved protein UCP028704, OpgC GBCGDNIH2_RS02440 1e98acf4a9dd27020ed0cc500cd491d2 271 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 3 266 4.1E-107 T 29-03-2018 IPR010223 ATP binding protein MinD, bacterial-type GO:0016887 GBCGDNIH2_RS02440 1e98acf4a9dd27020ed0cc500cd491d2 271 PIRSF PIRSF003092 1 271 4.5E-86 T 29-03-2018 IPR025501 ATP binding protein MinD GBCGDNIH2_RS02440 1e98acf4a9dd27020ed0cc500cd491d2 271 Gene3D G3DSA:3.40.50.300 1 251 1.7E-52 T 29-03-2018 GBCGDNIH2_RS02440 1e98acf4a9dd27020ed0cc500cd491d2 271 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 225 6.2E-21 T 29-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain GBCGDNIH2_RS02440 1e98acf4a9dd27020ed0cc500cd491d2 271 SUPERFAMILY SSF52540 1 253 1.56E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS02535 426df7d1023886b5624897766622f5a4 98 Pfam PF00550 Phosphopantetheine attachment site 23 93 5.4E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain GBCGDNIH2_RS02535 426df7d1023886b5624897766622f5a4 98 Gene3D G3DSA:1.10.1200.10 2 98 3.8E-15 T 29-03-2018 GBCGDNIH2_RS02535 426df7d1023886b5624897766622f5a4 98 SUPERFAMILY SSF47336 15 96 1.57E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain GBCGDNIH2_RS01840 bf2f2b73cfb28c6713174638698912b7 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 2.1E-5 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 GBCGDNIH2_RS01840 bf2f2b73cfb28c6713174638698912b7 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 2.1E-5 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 GBCGDNIH2_RS01840 bf2f2b73cfb28c6713174638698912b7 214 SMART SM00421 148 205 1.4E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 GBCGDNIH2_RS01840 bf2f2b73cfb28c6713174638698912b7 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 205 4.4E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 GBCGDNIH2_RS01840 bf2f2b73cfb28c6713174638698912b7 214 Gene3D G3DSA:1.10.10.10 129 213 9.1E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS01840 bf2f2b73cfb28c6713174638698912b7 214 SUPERFAMILY SSF46894 142 209 9.86E-13 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 GBCGDNIH2_RS01840 bf2f2b73cfb28c6713174638698912b7 214 Pfam PF00072 Response regulator receiver domain 8 118 1.1E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GBCGDNIH2_RS01840 bf2f2b73cfb28c6713174638698912b7 214 SMART SM00448 6 118 2.3E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GBCGDNIH2_RS01840 bf2f2b73cfb28c6713174638698912b7 214 SUPERFAMILY SSF52172 5 133 7.97E-32 T 29-03-2018 IPR011006 CheY-like superfamily GBCGDNIH2_RS01840 bf2f2b73cfb28c6713174638698912b7 214 Gene3D G3DSA:3.40.50.2300 5 128 7.3E-31 T 29-03-2018 GBCGDNIH2_RS11900 16617529e448d1024014a5c2e322337d 543 Pfam PF13742 OB-fold nucleic acid binding domain 29 122 2.7E-23 T 29-03-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 GBCGDNIH2_RS11900 16617529e448d1024014a5c2e322337d 543 Pfam PF02601 Exonuclease VII, large subunit 145 504 1.4E-88 T 29-03-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 GBCGDNIH2_RS11900 16617529e448d1024014a5c2e322337d 543 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 30 506 6.5E-121 T 29-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 GBCGDNIH2_RS11900 16617529e448d1024014a5c2e322337d 543 Gene3D G3DSA:2.40.50.140 28 124 1.8E-4 T 29-03-2018 GBCGDNIH2_RS11900 16617529e448d1024014a5c2e322337d 543 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 26 508 25.751 T 29-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 GBCGDNIH2_RS03610 775af0d436a3c30ef8f39dd9ccc6cf44 283 Pfam PF13371 Tetratricopeptide repeat 143 203 5.1E-11 T 29-03-2018 GBCGDNIH2_RS03610 775af0d436a3c30ef8f39dd9ccc6cf44 283 Gene3D G3DSA:1.25.40.10 205 279 1.4E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS03610 775af0d436a3c30ef8f39dd9ccc6cf44 283 SUPERFAMILY SSF48452 139 264 3.5E-27 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS03610 775af0d436a3c30ef8f39dd9ccc6cf44 283 Gene3D G3DSA:1.25.40.10 62 176 9.7E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS03610 775af0d436a3c30ef8f39dd9ccc6cf44 283 Gene3D G3DSA:1.25.40.10 177 204 7.1E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS03610 775af0d436a3c30ef8f39dd9ccc6cf44 283 Pfam PF13432 Tetratricopeptide repeat 207 263 2.2E-6 T 29-03-2018 GBCGDNIH2_RS03610 775af0d436a3c30ef8f39dd9ccc6cf44 283 SMART SM00028 196 229 0.0028 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 GBCGDNIH2_RS03610 775af0d436a3c30ef8f39dd9ccc6cf44 283 SMART SM00028 128 161 72.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 GBCGDNIH2_RS03610 775af0d436a3c30ef8f39dd9ccc6cf44 283 SMART SM00028 162 195 1.4 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 GBCGDNIH2_RS03610 775af0d436a3c30ef8f39dd9ccc6cf44 283 SMART SM00028 230 263 0.21 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 GBCGDNIH2_RS10000 8fe4500fec60520849f58be51e5db64b 326 Gene3D G3DSA:2.130.10.10 88 152 6.7E-17 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 GBCGDNIH2_RS10000 8fe4500fec60520849f58be51e5db64b 326 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 108 149 5.0E-9 T 29-03-2018 IPR011964 YVTN beta-propeller repeat GBCGDNIH2_RS10000 8fe4500fec60520849f58be51e5db64b 326 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 27 65 3.6E-9 T 29-03-2018 IPR011964 YVTN beta-propeller repeat GBCGDNIH2_RS10000 8fe4500fec60520849f58be51e5db64b 326 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 284 324 1.5E-12 T 29-03-2018 IPR011964 YVTN beta-propeller repeat GBCGDNIH2_RS10000 8fe4500fec60520849f58be51e5db64b 326 TIGRFAM TIGR03866 PQQ_ABC_repeats: PQQ-dependent catabolism-associated beta-propeller protein 19 326 7.5E-155 T 29-03-2018 IPR022456 PQQ-dependent catabolism-associated beta-propeller protein GBCGDNIH2_RS10000 8fe4500fec60520849f58be51e5db64b 326 Gene3D G3DSA:2.120.10.30 19 87 1.7E-10 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like GBCGDNIH2_RS10000 8fe4500fec60520849f58be51e5db64b 326 SUPERFAMILY SSF50974 4 326 5.75E-80 T 29-03-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 GBCGDNIH2_RS10000 8fe4500fec60520849f58be51e5db64b 326 Gene3D G3DSA:2.130.10.10 275 326 4.2E-7 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 GBCGDNIH2_RS10000 8fe4500fec60520849f58be51e5db64b 326 Gene3D G3DSA:2.130.10.10 153 274 1.5E-22 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 GBCGDNIH2_RS10000 8fe4500fec60520849f58be51e5db64b 326 Pfam PF07676 WD40-like Beta Propeller Repeat 104 116 0.18 T 29-03-2018 IPR011659 WD40-like Beta Propeller GBCGDNIH2_RS08435 a3133682554569a84cd73787558b37ad 122 Pfam PF13470 PIN domain 10 110 1.4E-7 T 29-03-2018 IPR002716 PIN domain GBCGDNIH2_RS05890 4e25be14398044ad0bd74845eb94e36f 213 SUPERFAMILY SSF51391 4 196 4.05E-61 T 29-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 GBCGDNIH2_RS05890 4e25be14398044ad0bd74845eb94e36f 213 Gene3D G3DSA:3.20.20.70 1 206 8.2E-41 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS05890 4e25be14398044ad0bd74845eb94e36f 213 Pfam PF02581 Thiamine monophosphate synthase 7 187 1.6E-49 T 29-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 GBCGDNIH2_RS05890 4e25be14398044ad0bd74845eb94e36f 213 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 6 193 1.6E-46 T 29-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 GBCGDNIH2_RS05890 4e25be14398044ad0bd74845eb94e36f 213 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 5 206 21.539 T 29-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 GBCGDNIH2_RS11590 133e787faa4b4bf07bdc85f787c958fe 438 Gene3D G3DSA:3.40.50.300 3 343 6.4E-53 T 29-03-2018 GBCGDNIH2_RS11590 133e787faa4b4bf07bdc85f787c958fe 438 SUPERFAMILY SSF52540 8 426 2.32E-79 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS11590 133e787faa4b4bf07bdc85f787c958fe 438 SMART SM01086 330 424 2.5E-20 T 29-03-2018 IPR019489 Clp ATPase, C-terminal GBCGDNIH2_RS11590 133e787faa4b4bf07bdc85f787c958fe 438 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 55 102 1.6E-6 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 GBCGDNIH2_RS11590 133e787faa4b4bf07bdc85f787c958fe 438 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 330 400 2.2E-6 T 29-03-2018 IPR019489 Clp ATPase, C-terminal GBCGDNIH2_RS11590 133e787faa4b4bf07bdc85f787c958fe 438 Pfam PF07724 AAA domain (Cdc48 subfamily) 197 324 5.4E-38 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 GBCGDNIH2_RS11590 133e787faa4b4bf07bdc85f787c958fe 438 Gene3D G3DSA:1.10.8.60 344 426 1.8E-28 T 29-03-2018 GBCGDNIH2_RS11590 133e787faa4b4bf07bdc85f787c958fe 438 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 7 438 8.4E-178 T 29-03-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 GBCGDNIH2_RS11590 133e787faa4b4bf07bdc85f787c958fe 438 SMART SM00382 51 327 3.9E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS11590 133e787faa4b4bf07bdc85f787c958fe 438 Hamap MF_00249 ATP-dependent protease ATPase subunit HslU [hslU]. 3 438 40.758 T 29-03-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 GBCGDNIH2_RS08850 582648689a0750b68389448e24e40825 265 SUPERFAMILY SSF75217 16 246 2.62E-92 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases GBCGDNIH2_RS08850 582648689a0750b68389448e24e40825 265 Gene3D G3DSA:3.40.1280.10 15 183 7.0E-68 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal GBCGDNIH2_RS08850 582648689a0750b68389448e24e40825 265 PIRSF PIRSF000386 16 259 2.5E-90 T 29-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 GBCGDNIH2_RS08850 582648689a0750b68389448e24e40825 265 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 19 242 5.0E-78 T 29-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 GBCGDNIH2_RS08850 582648689a0750b68389448e24e40825 265 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 39 235 6.8E-54 T 29-03-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 GBCGDNIH2_RS08850 582648689a0750b68389448e24e40825 265 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 265 104.036 T 29-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 GBCGDNIH2_RS08850 582648689a0750b68389448e24e40825 265 Gene3D G3DSA:1.10.1270.20 184 259 5.8E-31 T 29-03-2018 GBCGDNIH2_RS12110 728ba851be732b7c4fae2a02d71114ca 640 Hamap MF_01522 Low affinity potassium transport system protein kup [kup]. 20 640 33.35 T 29-03-2018 IPR023051 Potassium uptake protein, low affinity, Kup GBCGDNIH2_RS12110 728ba851be732b7c4fae2a02d71114ca 640 Pfam PF02705 K+ potassium transporter 29 562 1.2E-205 T 29-03-2018 IPR003855 Potassium transporter GO:0015079|GO:0016020|GO:0071805 GBCGDNIH2_RS10010 8f607222bfc10f889706cd4632ce2e0d 273 PIRSF PIRSF006648 2 262 5.4E-36 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 GBCGDNIH2_RS10010 8f607222bfc10f889706cd4632ce2e0d 273 Pfam PF01061 ABC-2 type transporter 18 233 5.9E-34 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 GBCGDNIH2_RS10010 8f607222bfc10f889706cd4632ce2e0d 273 PRINTS PR00164 ABC-2 type transport system membrane protein signature 210 229 1.5E-8 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 GBCGDNIH2_RS10010 8f607222bfc10f889706cd4632ce2e0d 273 PRINTS PR00164 ABC-2 type transport system membrane protein signature 150 174 1.5E-8 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 GBCGDNIH2_RS10010 8f607222bfc10f889706cd4632ce2e0d 273 PRINTS PR00164 ABC-2 type transport system membrane protein signature 33 54 1.5E-8 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 GBCGDNIH2_RS10010 8f607222bfc10f889706cd4632ce2e0d 273 TIGRFAM TIGR03861 phenyl_ABC_PedC: alcohol ABC transporter, permease protein 12 263 5.0E-124 T 29-03-2018 IPR022403 Alcohol ABC transporter, permease protein GBCGDNIH2_RS02745 d26ec7555f86b2f9d6331b403293cb0a 731 Pfam PF00271 Helicase conserved C-terminal domain 290 382 3.2E-22 T 29-03-2018 IPR001650 Helicase, C-terminal GBCGDNIH2_RS02745 d26ec7555f86b2f9d6331b403293cb0a 731 Pfam PF03880 DbpA RNA binding domain 526 586 5.5E-15 T 29-03-2018 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain GBCGDNIH2_RS02745 d26ec7555f86b2f9d6331b403293cb0a 731 Pfam PF00270 DEAD/DEAH box helicase 67 237 3.7E-43 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 GBCGDNIH2_RS02745 d26ec7555f86b2f9d6331b403293cb0a 731 SUPERFAMILY SSF52540 118 393 5.0E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS02745 d26ec7555f86b2f9d6331b403293cb0a 731 SMART SM00487 62 265 4.0E-50 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain GBCGDNIH2_RS02745 d26ec7555f86b2f9d6331b403293cb0a 731 Gene3D G3DSA:3.40.50.300 266 536 1.1E-35 T 29-03-2018 GBCGDNIH2_RS02745 d26ec7555f86b2f9d6331b403293cb0a 731 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 196 204 - T 29-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site GBCGDNIH2_RS02745 d26ec7555f86b2f9d6331b403293cb0a 731 SMART SM00490 301 382 6.0E-27 T 29-03-2018 IPR001650 Helicase, C-terminal GBCGDNIH2_RS02745 d26ec7555f86b2f9d6331b403293cb0a 731 Gene3D G3DSA:3.40.50.300 34 265 2.0E-54 T 29-03-2018 GBCGDNIH2_RS01435 26fe0d966a24cfe6f6cc4dd4b2d80791 924 SUPERFAMILY SSF53955 110 323 5.06E-73 T 29-03-2018 IPR023346 Lysozyme-like domain GBCGDNIH2_RS01435 26fe0d966a24cfe6f6cc4dd4b2d80791 924 Gene3D G3DSA:3.40.710.10 329 887 4.2E-116 T 29-03-2018 GBCGDNIH2_RS01435 26fe0d966a24cfe6f6cc4dd4b2d80791 924 Pfam PF17092 Penicillin-binding protein OB-like domain 390 542 1.5E-21 T 29-03-2018 IPR031376 Penicillin-binding protein, OB-like domain GBCGDNIH2_RS01435 26fe0d966a24cfe6f6cc4dd4b2d80791 924 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 133 856 5.1E-177 T 29-03-2018 GBCGDNIH2_RS01435 26fe0d966a24cfe6f6cc4dd4b2d80791 924 Gene3D G3DSA:1.10.3810.10 115 317 7.0E-76 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 GBCGDNIH2_RS01435 26fe0d966a24cfe6f6cc4dd4b2d80791 924 SUPERFAMILY SSF56601 539 725 1.63E-118 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like GBCGDNIH2_RS01435 26fe0d966a24cfe6f6cc4dd4b2d80791 924 SUPERFAMILY SSF56601 334 386 1.63E-118 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like GBCGDNIH2_RS01435 26fe0d966a24cfe6f6cc4dd4b2d80791 924 SUPERFAMILY SSF56601 282 304 1.63E-118 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like GBCGDNIH2_RS01435 26fe0d966a24cfe6f6cc4dd4b2d80791 924 SUPERFAMILY SSF56601 761 876 1.63E-118 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like GBCGDNIH2_RS01435 26fe0d966a24cfe6f6cc4dd4b2d80791 924 Pfam PF00912 Transglycosylase 123 300 3.1E-60 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 GBCGDNIH2_RS01435 26fe0d966a24cfe6f6cc4dd4b2d80791 924 Pfam PF00905 Penicillin binding protein transpeptidase domain 767 851 4.4E-5 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 GBCGDNIH2_RS01435 26fe0d966a24cfe6f6cc4dd4b2d80791 924 Pfam PF00905 Penicillin binding protein transpeptidase domain 544 722 2.1E-23 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 GBCGDNIH2_RS03665 f91e578f8365865ca79a5dc744d9212e 400 SUPERFAMILY SSF53383 1 397 1.63E-109 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase GBCGDNIH2_RS03665 f91e578f8365865ca79a5dc744d9212e 400 Gene3D G3DSA:3.40.640.10 46 274 3.2E-45 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GBCGDNIH2_RS03665 f91e578f8365865ca79a5dc744d9212e 400 Gene3D G3DSA:3.90.1150.10 275 400 6.4E-31 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 GBCGDNIH2_RS03665 f91e578f8365865ca79a5dc744d9212e 400 Pfam PF00155 Aminotransferase class I and II 32 392 7.3E-69 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 GBCGDNIH2_RS03665 f91e578f8365865ca79a5dc744d9212e 400 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 236 249 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 GBCGDNIH2_RS07350 6702087002e4118d2161ee7472843765 225 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 6 214 1.5E-39 T 29-03-2018 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 GBCGDNIH2_RS07350 6702087002e4118d2161ee7472843765 225 TIGRFAM TIGR01868 casD_Cas5e: CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI 6 215 3.3E-28 T 29-03-2018 IPR010147 CRISPR-associated protein, CasD GO:0003723|GO:0051607 GBCGDNIH2_RS02815 d32b70713427007ab9fd81f9d7930195 123 PIRSF PIRSF002133 1 123 2.7E-54 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS02815 d32b70713427007ab9fd81f9d7930195 123 PRINTS PR01034 Ribosomal protein S12 signature 27 42 2.6E-59 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS02815 d32b70713427007ab9fd81f9d7930195 123 PRINTS PR01034 Ribosomal protein S12 signature 58 77 2.6E-59 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS02815 d32b70713427007ab9fd81f9d7930195 123 PRINTS PR01034 Ribosomal protein S12 signature 110 122 2.6E-59 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS02815 d32b70713427007ab9fd81f9d7930195 123 PRINTS PR01034 Ribosomal protein S12 signature 42 57 2.6E-59 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS02815 d32b70713427007ab9fd81f9d7930195 123 PRINTS PR01034 Ribosomal protein S12 signature 94 110 2.6E-59 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS02815 d32b70713427007ab9fd81f9d7930195 123 PRINTS PR01034 Ribosomal protein S12 signature 77 94 2.6E-59 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS02815 d32b70713427007ab9fd81f9d7930195 123 Pfam PF00164 Ribosomal protein S12/S23 13 123 2.3E-41 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS02815 d32b70713427007ab9fd81f9d7930195 123 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 123 8.6E-66 T 29-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS02815 d32b70713427007ab9fd81f9d7930195 123 Gene3D G3DSA:2.40.50.140 1 123 4.0E-64 T 29-03-2018 GBCGDNIH2_RS02815 d32b70713427007ab9fd81f9d7930195 123 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 38.514 T 29-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS02815 d32b70713427007ab9fd81f9d7930195 123 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS02815 d32b70713427007ab9fd81f9d7930195 123 SUPERFAMILY SSF50249 2 123 4.54E-51 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold GBCGDNIH2_RS05950 9e0cba1cb2560cc175831b79e820cddf 216 Gene3D G3DSA:3.40.109.10 2 191 3.3E-39 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 GBCGDNIH2_RS05950 9e0cba1cb2560cc175831b79e820cddf 216 TIGRFAM TIGR02476 BluB: 5,6-dimethylbenzimidazole synthase 7 210 2.0E-78 T 29-03-2018 IPR012825 5,6-dimethylbenzimidazole synthase BluB KEGG: 00740+1.13.11.79|MetaCyc: PWY-5508|MetaCyc: PWY-5523 GBCGDNIH2_RS05950 9e0cba1cb2560cc175831b79e820cddf 216 SUPERFAMILY SSF55469 14 198 3.53E-42 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 GBCGDNIH2_RS05950 9e0cba1cb2560cc175831b79e820cddf 216 Pfam PF00881 Nitroreductase family 19 189 2.0E-25 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 GBCGDNIH2_RS02710 e411e71974da76dabbf36b52322d1936 398 Pfam PF13531 Bacterial extracellular solute-binding protein 109 327 3.4E-7 T 29-03-2018 GBCGDNIH2_RS02710 e411e71974da76dabbf36b52322d1936 398 SUPERFAMILY SSF53850 110 374 3.45E-22 T 29-03-2018 GBCGDNIH2_RS02710 e411e71974da76dabbf36b52322d1936 398 Gene3D G3DSA:3.40.190.10 169 334 6.2E-13 T 29-03-2018 GBCGDNIH2_RS10895 bb2a51764255baacf331327471bf0e9d 310 PIRSF PIRSF000089 1 310 3.8E-106 T 29-03-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 GBCGDNIH2_RS10895 bb2a51764255baacf331327471bf0e9d 310 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 254 280 - T 29-03-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 GBCGDNIH2_RS10895 bb2a51764255baacf331327471bf0e9d 310 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 191 273 1.4E-35 T 29-03-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 GBCGDNIH2_RS10895 bb2a51764255baacf331327471bf0e9d 310 Pfam PF01012 Electron transfer flavoprotein domain 5 170 1.6E-41 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 GBCGDNIH2_RS10895 bb2a51764255baacf331327471bf0e9d 310 SMART SM00893 4 183 2.9E-51 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 GBCGDNIH2_RS10895 bb2a51764255baacf331327471bf0e9d 310 SUPERFAMILY SSF52402 4 186 2.44E-54 T 29-03-2018 GBCGDNIH2_RS10895 bb2a51764255baacf331327471bf0e9d 310 Gene3D G3DSA:3.40.50.620 2 184 3.5E-44 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GBCGDNIH2_RS10895 bb2a51764255baacf331327471bf0e9d 310 SUPERFAMILY SSF52467 190 309 1.64E-47 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain GBCGDNIH2_RS10895 bb2a51764255baacf331327471bf0e9d 310 Gene3D G3DSA:3.40.50.1220 186 310 8.7E-59 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain GBCGDNIH2_RS10465 11b3d8e7e7a95e086035a33f982ff7b6 155 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 14 133 1.2E-31 T 29-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 GBCGDNIH2_RS10465 11b3d8e7e7a95e086035a33f982ff7b6 155 Gene3D G3DSA:3.40.50.300 6 152 4.3E-39 T 29-03-2018 GBCGDNIH2_RS10465 11b3d8e7e7a95e086035a33f982ff7b6 155 SUPERFAMILY SSF52540 28 130 8.15E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS10465 11b3d8e7e7a95e086035a33f982ff7b6 155 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 13 137 1.3E-26 T 29-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 GBCGDNIH2_RS01300 40ad74ab57cdf6f9ae3142962197bcb7 394 Pfam PF00296 Luciferase-like monooxygenase 13 334 2.4E-89 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 GBCGDNIH2_RS01300 40ad74ab57cdf6f9ae3142962197bcb7 394 Gene3D G3DSA:3.20.20.30 10 367 5.4E-94 T 29-03-2018 GBCGDNIH2_RS01300 40ad74ab57cdf6f9ae3142962197bcb7 394 Hamap MF_01229 Alkanesulfonate monooxygenase [ssuD]. 12 390 68.96 T 29-03-2018 IPR019911 Alkanesulphonate monooxygenase, FMN-dependent GO:0008726|GO:0055114 KEGG: 00920+1.14.14.5 GBCGDNIH2_RS01300 40ad74ab57cdf6f9ae3142962197bcb7 394 SUPERFAMILY SSF51679 15 357 9.68E-100 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 GBCGDNIH2_RS01300 40ad74ab57cdf6f9ae3142962197bcb7 394 TIGRFAM TIGR03565 alk_sulf_monoox: alkanesulfonate monooxygenase, FMNH(2)-dependent 12 357 3.3E-187 T 29-03-2018 IPR019911 Alkanesulphonate monooxygenase, FMN-dependent GO:0008726|GO:0055114 KEGG: 00920+1.14.14.5 GBCGDNIH2_RS04245 3e8cbe10ec770cf787f413b17c9d9cf6 133 Pfam PF03840 Preprotein translocase SecG subunit 4 71 1.3E-18 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 GBCGDNIH2_RS04245 3e8cbe10ec770cf787f413b17c9d9cf6 133 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 3 73 4.9E-21 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 GBCGDNIH2_RS04245 3e8cbe10ec770cf787f413b17c9d9cf6 133 PRINTS PR01651 Protein-export SecG membrane protein signature 37 53 2.6E-18 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 GBCGDNIH2_RS04245 3e8cbe10ec770cf787f413b17c9d9cf6 133 PRINTS PR01651 Protein-export SecG membrane protein signature 53 75 2.6E-18 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 GBCGDNIH2_RS04245 3e8cbe10ec770cf787f413b17c9d9cf6 133 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 2.6E-18 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 GBCGDNIH2_RS09085 4a065f525af30fe54944ca22fb0268a4 251 SUPERFAMILY SSF56784 28 241 1.09E-34 T 29-03-2018 IPR023214 HAD-like domain GBCGDNIH2_RS09085 4a065f525af30fe54944ca22fb0268a4 251 TIGRFAM TIGR00685 T6PP: trehalose-phosphatase 26 227 8.0E-32 T 29-03-2018 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 GBCGDNIH2_RS09085 4a065f525af30fe54944ca22fb0268a4 251 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 29 222 1.4E-19 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 GBCGDNIH2_RS09085 4a065f525af30fe54944ca22fb0268a4 251 Gene3D G3DSA:3.40.50.1000 26 251 7.6E-22 T 29-03-2018 IPR023214 HAD-like domain GBCGDNIH2_RS09085 4a065f525af30fe54944ca22fb0268a4 251 Pfam PF02358 Trehalose-phosphatase 30 224 5.7E-30 T 29-03-2018 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 GBCGDNIH2_RS08755 a5731ac8b509520d801fba6f2b563a86 4268 SUPERFAMILY SSF51126 80 360 2.89E-57 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor GBCGDNIH2_RS08755 a5731ac8b509520d801fba6f2b563a86 4268 Pfam PF13332 Haemagluttinin repeat 2834 2882 0.0031 T 29-03-2018 IPR025157 Hemagglutinin repeat GBCGDNIH2_RS08755 a5731ac8b509520d801fba6f2b563a86 4268 Pfam PF13332 Haemagluttinin repeat 3124 3283 1.7E-9 T 29-03-2018 IPR025157 Hemagglutinin repeat GBCGDNIH2_RS08755 a5731ac8b509520d801fba6f2b563a86 4268 Pfam PF13332 Haemagluttinin repeat 3355 3524 4.0E-34 T 29-03-2018 IPR025157 Hemagglutinin repeat GBCGDNIH2_RS08755 a5731ac8b509520d801fba6f2b563a86 4268 Pfam PF13332 Haemagluttinin repeat 2973 3033 1.6E-6 T 29-03-2018 IPR025157 Hemagglutinin repeat GBCGDNIH2_RS08755 a5731ac8b509520d801fba6f2b563a86 4268 TIGRFAM TIGR01901 adhes_NPXG: filamentous hemagglutinin family N-terminal domain 106 204 1.5E-19 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal GBCGDNIH2_RS08755 a5731ac8b509520d801fba6f2b563a86 4268 Pfam PF05860 haemagglutination activity domain 86 206 2.7E-30 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal GBCGDNIH2_RS08755 a5731ac8b509520d801fba6f2b563a86 4268 SMART SM00912 88 208 1.3E-41 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal GBCGDNIH2_RS08755 a5731ac8b509520d801fba6f2b563a86 4268 Gene3D G3DSA:2.160.20.10 2732 2928 2.4E-5 T 29-03-2018 IPR012334 Pectin lyase fold GBCGDNIH2_RS08755 a5731ac8b509520d801fba6f2b563a86 4268 Gene3D G3DSA:2.160.20.10 1324 1478 4.2E-4 T 29-03-2018 IPR012334 Pectin lyase fold GBCGDNIH2_RS08755 a5731ac8b509520d801fba6f2b563a86 4268 Gene3D G3DSA:2.160.20.10 78 359 1.5E-53 T 29-03-2018 IPR012334 Pectin lyase fold GBCGDNIH2_RS08755 a5731ac8b509520d801fba6f2b563a86 4268 Gene3D G3DSA:2.160.20.10 1043 1121 0.0023 T 29-03-2018 IPR012334 Pectin lyase fold GBCGDNIH2_RS08755 a5731ac8b509520d801fba6f2b563a86 4268 Gene3D G3DSA:2.160.20.10 2283 2371 0.0015 T 29-03-2018 IPR012334 Pectin lyase fold GBCGDNIH2_RS08755 a5731ac8b509520d801fba6f2b563a86 4268 Gene3D G3DSA:2.160.20.10 1479 1556 0.0044 T 29-03-2018 IPR012334 Pectin lyase fold GBCGDNIH2_RS08755 a5731ac8b509520d801fba6f2b563a86 4268 Gene3D G3DSA:2.160.20.10 895 1042 8.0E-7 T 29-03-2018 IPR012334 Pectin lyase fold GBCGDNIH2_RS08755 a5731ac8b509520d801fba6f2b563a86 4268 Gene3D G3DSA:2.160.20.10 360 412 0.018 T 29-03-2018 IPR012334 Pectin lyase fold GBCGDNIH2_RS08755 a5731ac8b509520d801fba6f2b563a86 4268 Gene3D G3DSA:2.160.20.10 1245 1323 0.015 T 29-03-2018 IPR012334 Pectin lyase fold GBCGDNIH2_RS08755 a5731ac8b509520d801fba6f2b563a86 4268 Gene3D G3DSA:2.160.20.10 1668 1826 0.0068 T 29-03-2018 IPR012334 Pectin lyase fold GBCGDNIH2_RS08755 a5731ac8b509520d801fba6f2b563a86 4268 Gene3D G3DSA:2.160.20.10 663 747 0.025 T 29-03-2018 IPR012334 Pectin lyase fold GBCGDNIH2_RS08755 a5731ac8b509520d801fba6f2b563a86 4268 Gene3D G3DSA:2.160.20.10 1827 1963 5.6E-6 T 29-03-2018 IPR012334 Pectin lyase fold GBCGDNIH2_RS08755 a5731ac8b509520d801fba6f2b563a86 4268 Gene3D G3DSA:2.160.20.10 1122 1244 1.7E-4 T 29-03-2018 IPR012334 Pectin lyase fold GBCGDNIH2_RS08755 a5731ac8b509520d801fba6f2b563a86 4268 Gene3D G3DSA:2.160.20.10 527 662 1.8E-6 T 29-03-2018 IPR012334 Pectin lyase fold GBCGDNIH2_RS01100 0f8af2b1641a531e1683a688b86d7676 310 Gene3D G3DSA:3.30.420.40 7 123 2.1E-21 T 29-03-2018 GBCGDNIH2_RS01100 0f8af2b1641a531e1683a688b86d7676 310 SUPERFAMILY SSF53067 11 302 1.69E-60 T 29-03-2018 GBCGDNIH2_RS01100 0f8af2b1641a531e1683a688b86d7676 310 ProSitePatterns PS01125 ROK family signature. 138 165 - T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 GBCGDNIH2_RS01100 0f8af2b1641a531e1683a688b86d7676 310 Gene3D G3DSA:3.30.420.40 124 304 4.6E-53 T 29-03-2018 GBCGDNIH2_RS01100 0f8af2b1641a531e1683a688b86d7676 310 Pfam PF00480 ROK family 12 303 8.5E-75 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 GBCGDNIH2_RS00755 1e09d833ea4f1749392e6e750b2566cb 591 Pfam PF13899 Thioredoxin-like 488 566 7.5E-14 T 29-03-2018 GBCGDNIH2_RS00755 1e09d833ea4f1749392e6e750b2566cb 591 Gene3D G3DSA:2.60.40.1250 23 160 1.4E-11 T 29-03-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain GBCGDNIH2_RS00755 1e09d833ea4f1749392e6e750b2566cb 591 Pfam PF11412 Disulphide bond corrector protein DsbC 47 153 1.2E-18 T 29-03-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain GBCGDNIH2_RS00755 1e09d833ea4f1749392e6e750b2566cb 591 Gene3D G3DSA:3.40.30.10 475 591 6.6E-6 T 29-03-2018 GBCGDNIH2_RS00755 1e09d833ea4f1749392e6e750b2566cb 591 SUPERFAMILY SSF52833 490 588 8.78E-12 T 29-03-2018 IPR012336 Thioredoxin-like fold GBCGDNIH2_RS05450 7a7d8b633f27fa13b9cc454b44222995 376 PIRSF PIRSF006769 5 371 8.6E-121 T 29-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 GBCGDNIH2_RS05450 7a7d8b633f27fa13b9cc454b44222995 376 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 55 93 - T 29-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 GBCGDNIH2_RS05450 7a7d8b633f27fa13b9cc454b44222995 376 Gene3D G3DSA:3.40.140.10 6 129 1.6E-29 T 29-03-2018 GBCGDNIH2_RS05450 7a7d8b633f27fa13b9cc454b44222995 376 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 12 363 2.8E-103 T 29-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 GBCGDNIH2_RS05450 7a7d8b633f27fa13b9cc454b44222995 376 Pfam PF01872 RibD C-terminal domain 152 363 4.1E-44 T 29-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 GBCGDNIH2_RS05450 7a7d8b633f27fa13b9cc454b44222995 376 SUPERFAMILY SSF53927 9 148 1.49E-43 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 GBCGDNIH2_RS05450 7a7d8b633f27fa13b9cc454b44222995 376 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 12 104 5.2E-16 T 29-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain GBCGDNIH2_RS05450 7a7d8b633f27fa13b9cc454b44222995 376 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 151 366 8.2E-51 T 29-03-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 GBCGDNIH2_RS05450 7a7d8b633f27fa13b9cc454b44222995 376 Gene3D G3DSA:3.40.430.10 130 367 4.6E-70 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 GBCGDNIH2_RS05450 7a7d8b633f27fa13b9cc454b44222995 376 SUPERFAMILY SSF53597 150 365 1.07E-55 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 GBCGDNIH2_RS04920 64f8596220bb502116509aeed5f3b67a 234 Pfam PF02498 BRO family, N-terminal domain 14 98 3.0E-24 T 29-03-2018 IPR003497 BRO N-terminal domain GBCGDNIH2_RS04920 64f8596220bb502116509aeed5f3b67a 234 SMART SM01040 13 98 8.4E-40 T 29-03-2018 IPR003497 BRO N-terminal domain GBCGDNIH2_RS09115 722260fbf5d96a9251cc01c42666a572 154 SUPERFAMILY SSF55298 4 153 3.93E-48 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like GBCGDNIH2_RS09115 722260fbf5d96a9251cc01c42666a572 154 Pfam PF14588 YjgF/chorismate_mutase-like, putative endoribonuclease 6 148 3.7E-30 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like GBCGDNIH2_RS09115 722260fbf5d96a9251cc01c42666a572 154 Gene3D G3DSA:3.30.1330.40 1 154 1.3E-27 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like GBCGDNIH2_RS01140 3e2f8b82670f869ff937129c9810f8d6 277 Gene3D G3DSA:3.40.50.720 9 268 3.5E-40 T 29-03-2018 GBCGDNIH2_RS01140 3e2f8b82670f869ff937129c9810f8d6 277 PIRSF PIRSF000094 9 267 1.7E-106 T 29-03-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 GBCGDNIH2_RS01140 3e2f8b82670f869ff937129c9810f8d6 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 188 205 2.1E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS01140 3e2f8b82670f869ff937129c9810f8d6 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 186 2.1E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS01140 3e2f8b82670f869ff937129c9810f8d6 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 223 243 2.1E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS01140 3e2f8b82670f869ff937129c9810f8d6 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 2.1E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS01140 3e2f8b82670f869ff937129c9810f8d6 277 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 260 3.9E-86 T 29-03-2018 GBCGDNIH2_RS01140 3e2f8b82670f869ff937129c9810f8d6 277 SUPERFAMILY SSF51735 13 264 3.89E-65 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS05410 d0c35b44102250313f6a09a36a24fb09 107 SUPERFAMILY SSF54292 5 105 5.88E-29 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 GBCGDNIH2_RS05410 d0c35b44102250313f6a09a36a24fb09 107 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 10 91 9.4E-10 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 GBCGDNIH2_RS05410 d0c35b44102250313f6a09a36a24fb09 107 Gene3D G3DSA:3.10.20.30 3 107 1.1E-24 T 29-03-2018 IPR012675 Beta-grasp domain GBCGDNIH2_RS05410 d0c35b44102250313f6a09a36a24fb09 107 PRINTS PR00355 Adrenodoxin signature 83 91 6.7E-7 T 29-03-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 GBCGDNIH2_RS05410 d0c35b44102250313f6a09a36a24fb09 107 PRINTS PR00355 Adrenodoxin signature 40 50 6.7E-7 T 29-03-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 GBCGDNIH2_RS05410 d0c35b44102250313f6a09a36a24fb09 107 PRINTS PR00355 Adrenodoxin signature 59 73 6.7E-7 T 29-03-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 GBCGDNIH2_RS09950 431d079faf88363956464f3cc2e4e38c 329 SMART SM00228 236 307 1.5E-7 T 29-03-2018 IPR001478 PDZ domain GO:0005515 GBCGDNIH2_RS09950 431d079faf88363956464f3cc2e4e38c 329 Gene3D G3DSA:2.40.10.10 12 128 3.8E-9 T 29-03-2018 GBCGDNIH2_RS09950 431d079faf88363956464f3cc2e4e38c 329 Gene3D G3DSA:2.30.42.10 242 315 5.6E-16 T 29-03-2018 GBCGDNIH2_RS09950 431d079faf88363956464f3cc2e4e38c 329 SUPERFAMILY SSF50494 23 229 8.73E-18 T 29-03-2018 IPR009003 Peptidase S1, PA clan GBCGDNIH2_RS09950 431d079faf88363956464f3cc2e4e38c 329 Pfam PF13180 PDZ domain 236 314 2.2E-14 T 29-03-2018 IPR001478 PDZ domain GO:0005515 GBCGDNIH2_RS09950 431d079faf88363956464f3cc2e4e38c 329 Gene3D G3DSA:2.40.10.10 129 240 6.6E-4 T 29-03-2018 GBCGDNIH2_RS09950 431d079faf88363956464f3cc2e4e38c 329 SUPERFAMILY SSF50156 208 314 2.37E-16 T 29-03-2018 IPR001478 PDZ domain GO:0005515 GBCGDNIH2_RS09950 431d079faf88363956464f3cc2e4e38c 329 PRINTS PR00834 HtrA/DegQ protease family signature 68 80 5.7E-9 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 GBCGDNIH2_RS09950 431d079faf88363956464f3cc2e4e38c 329 PRINTS PR00834 HtrA/DegQ protease family signature 185 202 5.7E-9 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 GBCGDNIH2_RS09950 431d079faf88363956464f3cc2e4e38c 329 PRINTS PR00834 HtrA/DegQ protease family signature 89 109 5.7E-9 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 GBCGDNIH2_RS09950 431d079faf88363956464f3cc2e4e38c 329 PRINTS PR00834 HtrA/DegQ protease family signature 264 276 5.7E-9 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 GBCGDNIH2_RS09755 7d3ec0119bcfdf185ae438f0dca7dcd4 1523 SUPERFAMILY SSF52540 3 215 2.29E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS09755 7d3ec0119bcfdf185ae438f0dca7dcd4 1523 SUPERFAMILY SSF52540 1391 1500 2.29E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS09755 7d3ec0119bcfdf185ae438f0dca7dcd4 1523 Gene3D G3DSA:1.20.120.330 922 1083 2.8E-5 T 29-03-2018 GBCGDNIH2_RS09755 7d3ec0119bcfdf185ae438f0dca7dcd4 1523 Gene3D G3DSA:1.20.120.330 614 730 0.098 T 29-03-2018 GBCGDNIH2_RS09755 7d3ec0119bcfdf185ae438f0dca7dcd4 1523 Gene3D G3DSA:3.40.50.300 1287 1521 3.0E-25 T 29-03-2018 GBCGDNIH2_RS09755 7d3ec0119bcfdf185ae438f0dca7dcd4 1523 SMART SM00968 691 781 0.0023 T 29-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 GBCGDNIH2_RS09755 7d3ec0119bcfdf185ae438f0dca7dcd4 1523 PIRSF PIRSF005719 4 279 1.4E-81 T 29-03-2018 IPR024704 Structural maintenance of chromosomes protein GBCGDNIH2_RS09755 7d3ec0119bcfdf185ae438f0dca7dcd4 1523 PIRSF PIRSF005719 1013 1515 1.6E-100 T 29-03-2018 IPR024704 Structural maintenance of chromosomes protein GBCGDNIH2_RS09755 7d3ec0119bcfdf185ae438f0dca7dcd4 1523 PIRSF PIRSF005719 237 440 2.6E-6 T 29-03-2018 IPR024704 Structural maintenance of chromosomes protein GBCGDNIH2_RS09755 7d3ec0119bcfdf185ae438f0dca7dcd4 1523 PIRSF PIRSF005719 410 1016 4.6E-21 T 29-03-2018 IPR024704 Structural maintenance of chromosomes protein GBCGDNIH2_RS09755 7d3ec0119bcfdf185ae438f0dca7dcd4 1523 SUPERFAMILY SSF75553 657 807 1.57E-6 T 29-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 GBCGDNIH2_RS09755 7d3ec0119bcfdf185ae438f0dca7dcd4 1523 Gene3D G3DSA:3.40.50.300 3 185 3.8E-30 T 29-03-2018 GBCGDNIH2_RS09755 7d3ec0119bcfdf185ae438f0dca7dcd4 1523 Pfam PF02463 RecF/RecN/SMC N terminal domain 6 1500 7.8E-56 T 29-03-2018 IPR003395 RecF/RecN/SMC, N-terminal GBCGDNIH2_RS09755 7d3ec0119bcfdf185ae438f0dca7dcd4 1523 Gene3D G3DSA:1.10.287.620 1099 1273 0.0037 T 29-03-2018 GBCGDNIH2_RS09755 7d3ec0119bcfdf185ae438f0dca7dcd4 1523 Gene3D G3DSA:1.10.287.620 228 386 0.001 T 29-03-2018 GBCGDNIH2_RS09755 7d3ec0119bcfdf185ae438f0dca7dcd4 1523 Hamap MF_01894 Chromosome partition protein Smc [smc]. 3 1509 19.775 T 29-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 GBCGDNIH2_RS06450 95736be3ef74f6bbdca8c0cd0f003dce 273 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 75 224 1.4E-22 T 29-03-2018 IPR006342 Methyltransferase FkbM GBCGDNIH2_RS06450 95736be3ef74f6bbdca8c0cd0f003dce 273 Pfam PF05050 Methyltransferase FkbM domain 76 243 4.6E-17 T 29-03-2018 IPR006342 Methyltransferase FkbM GBCGDNIH2_RS06450 95736be3ef74f6bbdca8c0cd0f003dce 273 Gene3D G3DSA:3.40.50.150 59 250 7.5E-24 T 29-03-2018 GBCGDNIH2_RS06450 95736be3ef74f6bbdca8c0cd0f003dce 273 SUPERFAMILY SSF53335 6 244 2.17E-45 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GBCGDNIH2_RS05175 baa16a14d79e3618863be66c113eb40a 499 Pfam PF01425 Amidase 25 471 1.5E-159 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 GBCGDNIH2_RS05175 baa16a14d79e3618863be66c113eb40a 499 SUPERFAMILY SSF75304 4 488 1.18E-161 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 GBCGDNIH2_RS05175 baa16a14d79e3618863be66c113eb40a 499 ProSitePatterns PS00571 Amidases signature. 157 188 - T 29-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 GBCGDNIH2_RS05175 baa16a14d79e3618863be66c113eb40a 499 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 12 483 92.93 T 29-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 GBCGDNIH2_RS05175 baa16a14d79e3618863be66c113eb40a 499 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 16 481 1.9E-177 T 29-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 GBCGDNIH2_RS05175 baa16a14d79e3618863be66c113eb40a 499 Gene3D G3DSA:3.90.1300.10 2 490 5.3E-173 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 GBCGDNIH2_RS08585 9f0a64f2a5e59fd113e40c8d736a27bd 341 Gene3D G3DSA:3.40.50.720 11 177 8.1E-26 T 29-03-2018 GBCGDNIH2_RS08585 9f0a64f2a5e59fd113e40c8d736a27bd 341 Gene3D G3DSA:3.90.25.10 178 341 3.4E-38 T 29-03-2018 GBCGDNIH2_RS08585 9f0a64f2a5e59fd113e40c8d736a27bd 341 SUPERFAMILY SSF51735 15 336 3.05E-85 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS08585 9f0a64f2a5e59fd113e40c8d736a27bd 341 Pfam PF01370 NAD dependent epimerase/dehydratase family 17 263 2.6E-51 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 GBCGDNIH2_RS08585 9f0a64f2a5e59fd113e40c8d736a27bd 341 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 15 337 5.1E-118 T 29-03-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-70370 GBCGDNIH2_RS03225 e51264e6c8e13dbd778a4cfd3172359b 355 Gene3D G3DSA:3.40.630.10 60 326 2.9E-12 T 29-03-2018 GBCGDNIH2_RS03225 e51264e6c8e13dbd778a4cfd3172359b 355 SUPERFAMILY SSF53187 37 348 3.89E-56 T 29-03-2018 GBCGDNIH2_RS03225 e51264e6c8e13dbd778a4cfd3172359b 355 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 68 278 1.4E-15 T 29-03-2018 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0008152|GO:0016788 GBCGDNIH2_RS11145 4c1a992a1108d0f50dce2eb7560b673c 205 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 1 204 25.738 T 29-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 GBCGDNIH2_RS11145 4c1a992a1108d0f50dce2eb7560b673c 205 Pfam PF01121 Dephospho-CoA kinase 3 182 8.5E-44 T 29-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 GBCGDNIH2_RS11145 4c1a992a1108d0f50dce2eb7560b673c 205 SUPERFAMILY SSF52540 2 201 2.38E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS11145 4c1a992a1108d0f50dce2eb7560b673c 205 Gene3D G3DSA:3.40.50.300 1 205 1.6E-37 T 29-03-2018 GBCGDNIH2_RS11145 4c1a992a1108d0f50dce2eb7560b673c 205 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 3 192 1.2E-35 T 29-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 GBCGDNIH2_RS10680 5167a0c9d95295b844bae9b64891019d 360 Pfam PF00294 pfkB family carbohydrate kinase 54 348 2.6E-14 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB GBCGDNIH2_RS10680 5167a0c9d95295b844bae9b64891019d 360 Gene3D G3DSA:3.40.1190.20 48 360 1.8E-29 T 29-03-2018 IPR029056 Ribokinase-like GBCGDNIH2_RS10680 5167a0c9d95295b844bae9b64891019d 360 SUPERFAMILY SSF53613 54 358 2.53E-30 T 29-03-2018 IPR029056 Ribokinase-like GBCGDNIH2_RS12255 1812c5f85348b1e52b384760b28ee005 433 Gene3D G3DSA:3.40.50.2300 186 387 7.0E-24 T 29-03-2018 GBCGDNIH2_RS12255 1812c5f85348b1e52b384760b28ee005 433 Pfam PF13458 Periplasmic binding protein 72 219 9.6E-18 T 29-03-2018 IPR028081 Leucine-binding protein domain GBCGDNIH2_RS12255 1812c5f85348b1e52b384760b28ee005 433 SUPERFAMILY SSF53822 274 420 2.94E-53 T 29-03-2018 IPR028082 Periplasmic binding protein-like I GBCGDNIH2_RS12255 1812c5f85348b1e52b384760b28ee005 433 SUPERFAMILY SSF53822 72 238 2.94E-53 T 29-03-2018 IPR028082 Periplasmic binding protein-like I GBCGDNIH2_RS12255 1812c5f85348b1e52b384760b28ee005 433 Gene3D G3DSA:3.40.50.2300 68 185 4.0E-17 T 29-03-2018 GBCGDNIH2_RS02860 426e1365a5bd5b4ccd6d93f7ed2bfe4c 133 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 13 122 24.152 T 29-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS02860 426e1365a5bd5b4ccd6d93f7ed2bfe4c 133 Gene3D G3DSA:3.90.470.10 1 133 9.9E-37 T 29-03-2018 GBCGDNIH2_RS02860 426e1365a5bd5b4ccd6d93f7ed2bfe4c 133 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 19 119 6.0E-28 T 29-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS02860 426e1365a5bd5b4ccd6d93f7ed2bfe4c 133 ProSitePatterns PS00464 Ribosomal protein L22 signature. 95 119 - T 29-03-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02860 426e1365a5bd5b4ccd6d93f7ed2bfe4c 133 SUPERFAMILY SSF54843 11 123 7.72E-37 T 29-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 GBCGDNIH2_RS02860 426e1365a5bd5b4ccd6d93f7ed2bfe4c 133 Pfam PF00237 Ribosomal protein L22p/L17e 18 119 6.6E-29 T 29-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 GBCGDNIH2_RS04155 15e8549f63decdb4b88160ab601e9aa5 186 SUPERFAMILY SSF52833 24 183 2.54E-13 T 29-03-2018 IPR012336 Thioredoxin-like fold GBCGDNIH2_RS04155 15e8549f63decdb4b88160ab601e9aa5 186 Pfam PF08534 Redoxin 25 174 4.0E-8 T 29-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 GBCGDNIH2_RS04155 15e8549f63decdb4b88160ab601e9aa5 186 Gene3D G3DSA:3.40.30.10 21 183 3.2E-12 T 29-03-2018 GBCGDNIH2_RS00650 1aaaf1c52ec3f75dfdbeb5dff050856b 477 PRINTS PR00149 Fumarate lyase superfamily signature 292 308 1.6E-28 T 29-03-2018 IPR000362 Fumarate lyase family GBCGDNIH2_RS00650 1aaaf1c52ec3f75dfdbeb5dff050856b 477 PRINTS PR00149 Fumarate lyase superfamily signature 164 182 1.6E-28 T 29-03-2018 IPR000362 Fumarate lyase family GBCGDNIH2_RS00650 1aaaf1c52ec3f75dfdbeb5dff050856b 477 PRINTS PR00149 Fumarate lyase superfamily signature 248 275 1.6E-28 T 29-03-2018 IPR000362 Fumarate lyase family GBCGDNIH2_RS00650 1aaaf1c52ec3f75dfdbeb5dff050856b 477 PRINTS PR00149 Fumarate lyase superfamily signature 119 137 1.6E-28 T 29-03-2018 IPR000362 Fumarate lyase family GBCGDNIH2_RS00650 1aaaf1c52ec3f75dfdbeb5dff050856b 477 PRINTS PR00145 Argininosuccinate lyase family signature 210 226 5.1E-65 T 29-03-2018 GBCGDNIH2_RS00650 1aaaf1c52ec3f75dfdbeb5dff050856b 477 PRINTS PR00145 Argininosuccinate lyase family signature 118 140 5.1E-65 T 29-03-2018 GBCGDNIH2_RS00650 1aaaf1c52ec3f75dfdbeb5dff050856b 477 PRINTS PR00145 Argininosuccinate lyase family signature 159 179 5.1E-65 T 29-03-2018 GBCGDNIH2_RS00650 1aaaf1c52ec3f75dfdbeb5dff050856b 477 PRINTS PR00145 Argininosuccinate lyase family signature 292 308 5.1E-65 T 29-03-2018 GBCGDNIH2_RS00650 1aaaf1c52ec3f75dfdbeb5dff050856b 477 PRINTS PR00145 Argininosuccinate lyase family signature 327 346 5.1E-65 T 29-03-2018 GBCGDNIH2_RS00650 1aaaf1c52ec3f75dfdbeb5dff050856b 477 PRINTS PR00145 Argininosuccinate lyase family signature 248 272 5.1E-65 T 29-03-2018 GBCGDNIH2_RS00650 1aaaf1c52ec3f75dfdbeb5dff050856b 477 SUPERFAMILY SSF48557 23 475 1.38E-148 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 GBCGDNIH2_RS00650 1aaaf1c52ec3f75dfdbeb5dff050856b 477 Pfam PF14698 Argininosuccinate lyase C-terminal 380 449 1.4E-23 T 29-03-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 GBCGDNIH2_RS00650 1aaaf1c52ec3f75dfdbeb5dff050856b 477 TIGRFAM TIGR00838 argH: argininosuccinate lyase 21 472 2.6E-181 T 29-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 GBCGDNIH2_RS00650 1aaaf1c52ec3f75dfdbeb5dff050856b 477 Hamap MF_00006 Argininosuccinate lyase [argH]. 19 471 42.128 T 29-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 GBCGDNIH2_RS00650 1aaaf1c52ec3f75dfdbeb5dff050856b 477 ProSitePatterns PS00163 Fumarate lyases signature. 292 301 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 GBCGDNIH2_RS00650 1aaaf1c52ec3f75dfdbeb5dff050856b 477 Gene3D G3DSA:1.20.200.10 124 391 8.2E-94 T 29-03-2018 GBCGDNIH2_RS00650 1aaaf1c52ec3f75dfdbeb5dff050856b 477 Gene3D G3DSA:1.10.275.10 19 123 5.7E-38 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal GBCGDNIH2_RS00650 1aaaf1c52ec3f75dfdbeb5dff050856b 477 Pfam PF00206 Lyase 25 317 2.2E-78 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal GBCGDNIH2_RS00650 1aaaf1c52ec3f75dfdbeb5dff050856b 477 Gene3D G3DSA:1.10.40.30 392 450 2.3E-26 T 29-03-2018 GBCGDNIH2_RS11460 c1f4547fd503ea4d595cc18f26b0260c 79 Pfam PF00550 Phosphopantetheine attachment site 6 73 1.1E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain GBCGDNIH2_RS11460 c1f4547fd503ea4d595cc18f26b0260c 79 SUPERFAMILY SSF47336 1 76 3.53E-24 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain GBCGDNIH2_RS11460 c1f4547fd503ea4d595cc18f26b0260c 79 Gene3D G3DSA:1.10.1200.10 1 79 2.7E-28 T 29-03-2018 GBCGDNIH2_RS11460 c1f4547fd503ea4d595cc18f26b0260c 79 ProSitePatterns PS00012 Phosphopantetheine attachment site. 32 47 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site GBCGDNIH2_RS11460 c1f4547fd503ea4d595cc18f26b0260c 79 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 1 77 3.0E-34 T 29-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 GBCGDNIH2_RS11460 c1f4547fd503ea4d595cc18f26b0260c 79 Hamap MF_01217 Acyl carrier protein [acpP]. 3 77 23.139 T 29-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 GBCGDNIH2_RS11460 c1f4547fd503ea4d595cc18f26b0260c 79 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 41 76 5.0E-11 T 29-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 GBCGDNIH2_RS02835 74708c6648ff630adff92fe6f2bf7ec8 231 Pfam PF00297 Ribosomal protein L3 64 182 5.1E-12 T 29-03-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS02835 74708c6648ff630adff92fe6f2bf7ec8 231 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 4 205 4.3E-85 T 29-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS02835 74708c6648ff630adff92fe6f2bf7ec8 231 ProSitePatterns PS00474 Ribosomal protein L3 signature. 102 125 - T 29-03-2018 IPR019926 Ribosomal protein L3, conserved site GBCGDNIH2_RS02835 74708c6648ff630adff92fe6f2bf7ec8 231 Gene3D G3DSA:4.10.960.10 58 166 8.5E-35 T 29-03-2018 GBCGDNIH2_RS02835 74708c6648ff630adff92fe6f2bf7ec8 231 SUPERFAMILY SSF50447 1 219 1.32E-80 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain GBCGDNIH2_RS02835 74708c6648ff630adff92fe6f2bf7ec8 231 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 2 208 36.363 T 29-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS02190 1030ff1fe6233d1787e6279ab5a39f79 304 Pfam PF08478 POTRA domain, FtsQ-type 93 160 6.3E-17 T 29-03-2018 IPR013685 POTRA domain, FtsQ-type GBCGDNIH2_RS02190 1030ff1fe6233d1787e6279ab5a39f79 304 Pfam PF03799 Cell division protein FtsQ 164 277 5.2E-18 T 29-03-2018 IPR005548 Cell division protein FtsQ/DivIB GBCGDNIH2_RS02190 1030ff1fe6233d1787e6279ab5a39f79 304 Hamap MF_00911 Cell division protein FtsQ [ftsQ]. 68 298 20.066 T 29-03-2018 IPR026579 Cell division protein FtsQ GO:0090529 GBCGDNIH2_RS08895 c5565175fd2cf5ab3e9a770c734f909c 849 Gene3D G3DSA:3.40.50.300 237 473 3.2E-18 T 29-03-2018 GBCGDNIH2_RS08895 c5565175fd2cf5ab3e9a770c734f909c 849 Gene3D G3DSA:3.40.50.300 516 659 1.9E-7 T 29-03-2018 GBCGDNIH2_RS08895 c5565175fd2cf5ab3e9a770c734f909c 849 SMART SM00487 252 480 2.4E-5 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain GBCGDNIH2_RS08895 c5565175fd2cf5ab3e9a770c734f909c 849 Gene3D G3DSA:1.10.3210.10 36 236 5.4E-5 T 29-03-2018 GBCGDNIH2_RS08895 c5565175fd2cf5ab3e9a770c734f909c 849 SUPERFAMILY SSF52540 274 321 1.07E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS08895 c5565175fd2cf5ab3e9a770c734f909c 849 SUPERFAMILY SSF52540 363 453 1.07E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS08895 c5565175fd2cf5ab3e9a770c734f909c 849 SUPERFAMILY SSF52540 499 642 1.07E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS08895 c5565175fd2cf5ab3e9a770c734f909c 849 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 22 204 4.7E-19 T 29-03-2018 IPR006483 CRISPR-associated Cas3-HD domain GBCGDNIH2_RS08895 c5565175fd2cf5ab3e9a770c734f909c 849 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 276 640 5.6E-47 T 29-03-2018 IPR006474 Helicase Cas3, CRISPR-associated, core GBCGDNIH2_RS08895 c5565175fd2cf5ab3e9a770c734f909c 849 Pfam PF00270 DEAD/DEAH box helicase 258 451 1.3E-7 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 GBCGDNIH2_RS12395 df278f81ffac7763cfbd106e760c9194 990 SUPERFAMILY SSF53448 670 801 1.06E-40 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS12395 df278f81ffac7763cfbd106e760c9194 990 SUPERFAMILY SSF53448 834 904 1.06E-40 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS12395 df278f81ffac7763cfbd106e760c9194 990 Pfam PF00535 Glycosyl transferase family 2 420 534 1.8E-29 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 GBCGDNIH2_RS12395 df278f81ffac7763cfbd106e760c9194 990 SUPERFAMILY SSF53448 419 637 1.22E-52 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS12395 df278f81ffac7763cfbd106e760c9194 990 Gene3D G3DSA:3.90.550.10 371 651 3.8E-47 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS12395 df278f81ffac7763cfbd106e760c9194 990 Gene3D G3DSA:3.90.550.10 662 968 2.6E-34 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS12395 df278f81ffac7763cfbd106e760c9194 990 Pfam PF13641 Glycosyltransferase like family 2 671 905 4.5E-10 T 29-03-2018 GBCGDNIH2_RS03050 fd24df658394192fe1c8adbef6f45217 265 Pfam PF00156 Phosphoribosyl transferase domain 192 246 1.7E-6 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 GBCGDNIH2_RS03050 fd24df658394192fe1c8adbef6f45217 265 SUPERFAMILY SSF53271 74 253 5.11E-29 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like GBCGDNIH2_RS03050 fd24df658394192fe1c8adbef6f45217 265 Gene3D G3DSA:3.40.50.2020 83 255 2.5E-23 T 29-03-2018 GBCGDNIH2_RS00695 3d699521f3b592dff932bf9515e28946 482 PIRSF PIRSF006446 3 456 1.9E-190 T 29-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 GBCGDNIH2_RS00695 3d699521f3b592dff932bf9515e28946 482 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 10 438 2.0E-154 T 29-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 GBCGDNIH2_RS12515 c8862f982836ec4d155769fc5da2b162 332 Pfam PF00579 tRNA synthetases class I (W and Y) 3 260 3.3E-70 T 29-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 GBCGDNIH2_RS12515 c8862f982836ec4d155769fc5da2b162 332 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 10 19 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 GBCGDNIH2_RS12515 c8862f982836ec4d155769fc5da2b162 332 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 14 30 9.6E-26 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 GBCGDNIH2_RS12515 c8862f982836ec4d155769fc5da2b162 332 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 140 161 9.6E-26 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 GBCGDNIH2_RS12515 c8862f982836ec4d155769fc5da2b162 332 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 64 83 9.6E-26 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 GBCGDNIH2_RS12515 c8862f982836ec4d155769fc5da2b162 332 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 194 204 9.6E-26 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 GBCGDNIH2_RS12515 c8862f982836ec4d155769fc5da2b162 332 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 2 329 1.4E-91 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 GBCGDNIH2_RS12515 c8862f982836ec4d155769fc5da2b162 332 Gene3D G3DSA:1.10.240.10 201 312 1.5E-22 T 29-03-2018 GBCGDNIH2_RS12515 c8862f982836ec4d155769fc5da2b162 332 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 1 330 37.741 T 29-03-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 GBCGDNIH2_RS12515 c8862f982836ec4d155769fc5da2b162 332 Gene3D G3DSA:3.40.50.620 1 200 2.3E-75 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GBCGDNIH2_RS12515 c8862f982836ec4d155769fc5da2b162 332 SUPERFAMILY SSF52374 1 329 6.65E-88 T 29-03-2018 GBCGDNIH2_RS07705 13dd01779726714c0a3011df5ecfb780 507 PRINTS PR00702 Acriflavin resistance protein family signature 470 493 1.3E-7 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS07705 13dd01779726714c0a3011df5ecfb780 507 PRINTS PR00702 Acriflavin resistance protein family signature 395 419 1.3E-7 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS07705 13dd01779726714c0a3011df5ecfb780 507 PRINTS PR00702 Acriflavin resistance protein family signature 342 365 1.3E-7 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS07705 13dd01779726714c0a3011df5ecfb780 507 SUPERFAMILY SSF82866 303 500 1.7E-41 T 29-03-2018 GBCGDNIH2_RS07705 13dd01779726714c0a3011df5ecfb780 507 Gene3D G3DSA:1.20.1640.10 290 500 6.7E-32 T 29-03-2018 GBCGDNIH2_RS07705 13dd01779726714c0a3011df5ecfb780 507 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 1 507 41.635 T 29-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 GBCGDNIH2_RS07705 13dd01779726714c0a3011df5ecfb780 507 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 256 485 1.1E-77 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial GBCGDNIH2_RS07705 13dd01779726714c0a3011df5ecfb780 507 Pfam PF07549 SecD/SecF GG Motif 21 41 4.1E-4 T 29-03-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site GBCGDNIH2_RS07705 13dd01779726714c0a3011df5ecfb780 507 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 23 493 8.4E-137 T 29-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 GBCGDNIH2_RS07705 13dd01779726714c0a3011df5ecfb780 507 Pfam PF02355 Protein export membrane protein 328 496 1.3E-19 T 29-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial GBCGDNIH2_RS11465 9a7e308f00a59bf96ac58155ffb36f63 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 GBCGDNIH2_RS11465 9a7e308f00a59bf96ac58155ffb36f63 245 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 188 4.4E-7 T 29-03-2018 GBCGDNIH2_RS11465 9a7e308f00a59bf96ac58155ffb36f63 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 242 1.7E-64 T 29-03-2018 GBCGDNIH2_RS11465 9a7e308f00a59bf96ac58155ffb36f63 245 Gene3D G3DSA:3.40.50.720 1 44 2.8E-11 T 29-03-2018 GBCGDNIH2_RS11465 9a7e308f00a59bf96ac58155ffb36f63 245 Gene3D G3DSA:3.40.50.720 45 245 3.3E-65 T 29-03-2018 GBCGDNIH2_RS11465 9a7e308f00a59bf96ac58155ffb36f63 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 3.2E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS11465 9a7e308f00a59bf96ac58155ffb36f63 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 3.2E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS11465 9a7e308f00a59bf96ac58155ffb36f63 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 3.2E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS11465 9a7e308f00a59bf96ac58155ffb36f63 245 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 9 243 9.0E-93 T 29-03-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 GBCGDNIH2_RS11465 9a7e308f00a59bf96ac58155ffb36f63 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 1.3E-49 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS11465 9a7e308f00a59bf96ac58155ffb36f63 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 1.3E-49 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS11465 9a7e308f00a59bf96ac58155ffb36f63 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.3E-49 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS11465 9a7e308f00a59bf96ac58155ffb36f63 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 1.3E-49 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS11465 9a7e308f00a59bf96ac58155ffb36f63 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 1.3E-49 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS11465 9a7e308f00a59bf96ac58155ffb36f63 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 1.3E-49 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS11465 9a7e308f00a59bf96ac58155ffb36f63 245 SUPERFAMILY SSF51735 5 244 1.36E-85 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS00675 7a0aa771a42047ea7b17389f3a9c7bbe 208 ProDom PD207074 TRANSMEMBRANE MEMBRANE UNCHARACTERIZED RC1356 RP875 56 179 8.0E-9 T 29-03-2018 GBCGDNIH2_RS00675 7a0aa771a42047ea7b17389f3a9c7bbe 208 Pfam PF02698 DUF218 domain 56 162 8.1E-14 T 29-03-2018 IPR003848 Domain of unknown function DUF218 GBCGDNIH2_RS00675 7a0aa771a42047ea7b17389f3a9c7bbe 208 Gene3D G3DSA:3.40.50.620 27 173 5.4E-21 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GBCGDNIH2_RS07755 631911c2bbb5ea400d2f734136752fbf 521 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 20 498 7.1E-106 T 29-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 GBCGDNIH2_RS07755 631911c2bbb5ea400d2f734136752fbf 521 SUPERFAMILY SSF56954 70 502 3.66E-109 T 29-03-2018 GBCGDNIH2_RS07755 631911c2bbb5ea400d2f734136752fbf 521 SUPERFAMILY SSF56954 7 36 3.66E-109 T 29-03-2018 GBCGDNIH2_RS07755 631911c2bbb5ea400d2f734136752fbf 521 Pfam PF02321 Outer membrane efflux protein 319 496 7.6E-26 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 GBCGDNIH2_RS07755 631911c2bbb5ea400d2f734136752fbf 521 Pfam PF02321 Outer membrane efflux protein 81 286 6.1E-26 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 GBCGDNIH2_RS07755 631911c2bbb5ea400d2f734136752fbf 521 Gene3D G3DSA:1.20.1600.10 27 504 1.1E-98 T 29-03-2018 GBCGDNIH2_RS11600 a5647bd0396e928c7e6097675a1b88bd 295 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 34 265 9.5E-31 T 29-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA GBCGDNIH2_RS11600 a5647bd0396e928c7e6097675a1b88bd 295 TIGRFAM TIGR01459 HAD-SF-IIA-hyp4: HAD hydrolase, TIGR01459 family 25 264 8.4E-72 T 29-03-2018 IPR006356 HAD-superfamily hydrolase, subfamily IIA, hypothetical 3 GBCGDNIH2_RS11600 a5647bd0396e928c7e6097675a1b88bd 295 SUPERFAMILY SSF56784 32 285 1.23E-44 T 29-03-2018 IPR023214 HAD-like domain GBCGDNIH2_RS11600 a5647bd0396e928c7e6097675a1b88bd 295 Pfam PF13242 HAD-hyrolase-like 215 285 4.2E-18 T 29-03-2018 GBCGDNIH2_RS11600 a5647bd0396e928c7e6097675a1b88bd 295 Pfam PF13344 Haloacid dehalogenase-like hydrolase 34 138 8.4E-15 T 29-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA GBCGDNIH2_RS11600 a5647bd0396e928c7e6097675a1b88bd 295 Gene3D G3DSA:3.40.50.1000 25 290 6.7E-30 T 29-03-2018 IPR023214 HAD-like domain GBCGDNIH2_RS11055 f3cf91ed8a1b6a7c70e2d1c7f2dc8e8b 233 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 17 226 2.1E-58 T 29-03-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 GBCGDNIH2_RS11055 f3cf91ed8a1b6a7c70e2d1c7f2dc8e8b 233 SUPERFAMILY SSF161098 8 221 1.16E-46 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GBCGDNIH2_RS11055 f3cf91ed8a1b6a7c70e2d1c7f2dc8e8b 233 Gene3D G3DSA:1.10.3720.10 5 233 4.5E-39 T 29-03-2018 GBCGDNIH2_RS11055 f3cf91ed8a1b6a7c70e2d1c7f2dc8e8b 233 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 29 229 9.0E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GBCGDNIH2_RS12380 d6fb8f788029ddfe9e35246faf260679 174 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 66 166 3.9E-10 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS12380 d6fb8f788029ddfe9e35246faf260679 174 SUPERFAMILY SSF56770 46 167 4.97E-30 T 29-03-2018 GBCGDNIH2_RS12380 d6fb8f788029ddfe9e35246faf260679 174 Gene3D G3DSA:3.40.50.700 24 174 1.7E-13 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS00900 290b9c9ffa45245ca8068659e4fb3f11 225 SUPERFAMILY SSF47413 42 108 1.49E-16 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GBCGDNIH2_RS00900 290b9c9ffa45245ca8068659e4fb3f11 225 Pfam PF01381 Helix-turn-helix 48 100 1.0E-13 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 GBCGDNIH2_RS00900 290b9c9ffa45245ca8068659e4fb3f11 225 Gene3D G3DSA:1.10.260.40 34 109 1.1E-17 T 29-03-2018 GBCGDNIH2_RS00900 290b9c9ffa45245ca8068659e4fb3f11 225 Gene3D G3DSA:2.60.120.10 110 224 3.2E-11 T 29-03-2018 IPR014710 RmlC-like jelly roll fold GBCGDNIH2_RS00900 290b9c9ffa45245ca8068659e4fb3f11 225 SUPERFAMILY SSF51182 108 220 1.49E-21 T 29-03-2018 IPR011051 RmlC-like cupin domain GBCGDNIH2_RS00900 290b9c9ffa45245ca8068659e4fb3f11 225 SMART SM00530 47 102 6.6E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 GBCGDNIH2_RS00900 290b9c9ffa45245ca8068659e4fb3f11 225 Pfam PF07883 Cupin domain 164 219 6.9E-8 T 29-03-2018 IPR013096 Cupin 2, conserved barrel GBCGDNIH2_RS01095 87eea53f6f6eba2df2c9f23f2cb8811e 427 Hamap MF_01113 DNA polymerase IV [dinB]. 36 379 30.768 T 29-03-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 GBCGDNIH2_RS01095 87eea53f6f6eba2df2c9f23f2cb8811e 427 SUPERFAMILY SSF56672 36 266 1.69E-68 T 29-03-2018 GBCGDNIH2_RS01095 87eea53f6f6eba2df2c9f23f2cb8811e 427 SUPERFAMILY SSF100879 273 368 5.89E-26 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 GBCGDNIH2_RS01095 87eea53f6f6eba2df2c9f23f2cb8811e 427 Gene3D G3DSA:3.30.1490.100 277 379 1.2E-25 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 GBCGDNIH2_RS01095 87eea53f6f6eba2df2c9f23f2cb8811e 427 Pfam PF00817 impB/mucB/samB family 42 187 1.0E-43 T 29-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 GBCGDNIH2_RS01095 87eea53f6f6eba2df2c9f23f2cb8811e 427 Gene3D G3DSA:1.10.150.20 205 276 2.4E-11 T 29-03-2018 GBCGDNIH2_RS01095 87eea53f6f6eba2df2c9f23f2cb8811e 427 Gene3D G3DSA:3.30.70.270 74 146 8.3E-21 T 29-03-2018 GBCGDNIH2_RS01095 87eea53f6f6eba2df2c9f23f2cb8811e 427 Gene3D G3DSA:3.30.70.270 147 204 5.1E-9 T 29-03-2018 GBCGDNIH2_RS01095 87eea53f6f6eba2df2c9f23f2cb8811e 427 Pfam PF11799 impB/mucB/samB family C-terminal domain 269 373 6.0E-20 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 GBCGDNIH2_RS08790 43c8424e31bdb4e626c8ce668422a525 231 Gene3D G3DSA:3.40.50.880 1 230 5.7E-31 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like GBCGDNIH2_RS08790 43c8424e31bdb4e626c8ce668422a525 231 SUPERFAMILY SSF52317 1 225 8.76E-70 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like GBCGDNIH2_RS08790 43c8424e31bdb4e626c8ce668422a525 231 SMART SM01211 1 229 2.3E-125 T 29-03-2018 GBCGDNIH2_RS08790 43c8424e31bdb4e626c8ce668422a525 231 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 1 227 7.5E-85 T 29-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 GBCGDNIH2_RS08790 43c8424e31bdb4e626c8ce668422a525 231 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 1 227 41.04 T 29-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 GBCGDNIH2_RS08790 43c8424e31bdb4e626c8ce668422a525 231 PIRSF PIRSF001586 1 231 8.4E-80 T 29-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 GBCGDNIH2_RS08790 43c8424e31bdb4e626c8ce668422a525 231 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 3 212 8.4E-42 T 29-03-2018 GBCGDNIH2_RS02035 afc286aac82f1d9fee99fb2d05a9aae2 152 SUPERFAMILY SSF47413 16 91 4.41E-21 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GBCGDNIH2_RS02035 afc286aac82f1d9fee99fb2d05a9aae2 152 Pfam PF13560 Helix-turn-helix domain 25 79 8.8E-8 T 29-03-2018 GBCGDNIH2_RS02035 afc286aac82f1d9fee99fb2d05a9aae2 152 Gene3D G3DSA:3.30.1190.10 51 150 9.9E-6 T 29-03-2018 GBCGDNIH2_RS02035 afc286aac82f1d9fee99fb2d05a9aae2 152 SMART SM00530 28 83 3.6E-9 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 GBCGDNIH2_RS02035 afc286aac82f1d9fee99fb2d05a9aae2 152 Gene3D G3DSA:1.10.10.60 24 50 2.7E-6 T 29-03-2018 GBCGDNIH2_RS06615 3bf599b54d8897234dcb6eccd2c5df97 485 Gene3D G3DSA:3.30.43.10 3 105 4.9E-27 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 GBCGDNIH2_RS06615 3bf599b54d8897234dcb6eccd2c5df97 485 Pfam PF01565 FAD binding domain 53 191 7.5E-38 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 GBCGDNIH2_RS06615 3bf599b54d8897234dcb6eccd2c5df97 485 SUPERFAMILY SSF55103 231 471 1.64E-60 T 29-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 GBCGDNIH2_RS06615 3bf599b54d8897234dcb6eccd2c5df97 485 Gene3D G3DSA:3.30.465.10 106 250 1.8E-34 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 GBCGDNIH2_RS06615 3bf599b54d8897234dcb6eccd2c5df97 485 Pfam PF02913 FAD linked oxidases, C-terminal domain 228 468 2.4E-59 T 29-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 GBCGDNIH2_RS06615 3bf599b54d8897234dcb6eccd2c5df97 485 Gene3D G3DSA:1.10.45.10 429 468 2.2E-10 T 29-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 GBCGDNIH2_RS06615 3bf599b54d8897234dcb6eccd2c5df97 485 SUPERFAMILY SSF56176 19 228 2.15E-69 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 GBCGDNIH2_RS01805 0aaadc45a4470a6ed160d6e465da014a 347 Gene3D G3DSA:1.10.8.300 221 344 3.3E-23 T 29-03-2018 GBCGDNIH2_RS01805 0aaadc45a4470a6ed160d6e465da014a 347 PIRSF PIRSF002849 4 347 6.5E-78 T 29-03-2018 GBCGDNIH2_RS01805 0aaadc45a4470a6ed160d6e465da014a 347 SMART SM00382 49 193 5.7E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS01805 0aaadc45a4470a6ed160d6e465da014a 347 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 53 71 8.4E-6 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 GBCGDNIH2_RS01805 0aaadc45a4470a6ed160d6e465da014a 347 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 122 140 8.4E-6 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 GBCGDNIH2_RS01805 0aaadc45a4470a6ed160d6e465da014a 347 Gene3D G3DSA:3.40.50.300 33 201 6.4E-21 T 29-03-2018 GBCGDNIH2_RS01805 0aaadc45a4470a6ed160d6e465da014a 347 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 52 185 2.2E-25 T 29-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 GBCGDNIH2_RS01805 0aaadc45a4470a6ed160d6e465da014a 347 SUPERFAMILY SSF52540 29 201 3.66E-32 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS01805 0aaadc45a4470a6ed160d6e465da014a 347 SUPERFAMILY SSF52540 234 318 3.66E-32 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS09520 6dd494b303784f7649da3e3414a42047 300 Pfam PF01061 ABC-2 type transporter 66 261 1.8E-14 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 GBCGDNIH2_RS04145 b00ef5a87fe2428dd5a930f5565d2bd7 211 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 10 208 19.737 T 29-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 GBCGDNIH2_RS04145 b00ef5a87fe2428dd5a930f5565d2bd7 211 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 10 208 4.5E-48 T 29-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 GBCGDNIH2_RS04145 b00ef5a87fe2428dd5a930f5565d2bd7 211 SMART SM01207 13 200 8.9E-80 T 29-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 GBCGDNIH2_RS04145 b00ef5a87fe2428dd5a930f5565d2bd7 211 Pfam PF02660 Glycerol-3-phosphate acyltransferase 15 199 2.9E-48 T 29-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 GBCGDNIH2_RS07275 0d325361a77a4332e4e1cfbdfe2053c8 192 Gene3D G3DSA:2.60.40.790 28 166 5.5E-20 T 29-03-2018 IPR008978 HSP20-like chaperone GBCGDNIH2_RS07275 0d325361a77a4332e4e1cfbdfe2053c8 192 SUPERFAMILY SSF49764 61 165 2.44E-19 T 29-03-2018 IPR008978 HSP20-like chaperone GBCGDNIH2_RS07275 0d325361a77a4332e4e1cfbdfe2053c8 192 Pfam PF00011 Hsp20/alpha crystallin family 72 165 4.5E-18 T 29-03-2018 IPR002068 Alpha crystallin/Hsp20 domain GBCGDNIH2_RS08115 326b21253cc9d45705be23ff931917f4 950 ProSitePatterns PS00211 ABC transporters family signature. 852 866 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GBCGDNIH2_RS08115 326b21253cc9d45705be23ff931917f4 950 SMART SM00382 741 930 1.3E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS08115 326b21253cc9d45705be23ff931917f4 950 SUPERFAMILY SSF90123 398 701 1.7E-37 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 GBCGDNIH2_RS08115 326b21253cc9d45705be23ff931917f4 950 SUPERFAMILY SSF52540 708 949 7.67E-76 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS08115 326b21253cc9d45705be23ff931917f4 950 Pfam PF00005 ABC transporter 732 880 1.0E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GBCGDNIH2_RS08115 326b21253cc9d45705be23ff931917f4 950 TIGRFAM TIGR03797 NHLM_micro_ABC2: NHLM bacteriocin system ABC transporter, ATP-binding protein 263 949 1.3E-269 T 29-03-2018 IPR022515 NHPM bacteriocin system ABC transporter, ATP-binding protein GBCGDNIH2_RS08115 326b21253cc9d45705be23ff931917f4 950 Pfam PF00664 ABC transporter transmembrane region 404 671 2.2E-13 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 GBCGDNIH2_RS08115 326b21253cc9d45705be23ff931917f4 950 Gene3D G3DSA:3.40.50.300 702 950 2.1E-66 T 29-03-2018 GBCGDNIH2_RS08115 326b21253cc9d45705be23ff931917f4 950 Gene3D G3DSA:1.20.1560.10 384 701 5.4E-25 T 29-03-2018 GBCGDNIH2_RS02820 1bc528a107b354a2e50b6e89eac3bc5e 158 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 158 5.0E-69 T 29-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 GBCGDNIH2_RS02820 1bc528a107b354a2e50b6e89eac3bc5e 158 Pfam PF00177 Ribosomal protein S7p/S5e 1 151 1.2E-67 T 29-03-2018 IPR023798 Ribosomal protein S7 domain GBCGDNIH2_RS02820 1bc528a107b354a2e50b6e89eac3bc5e 158 SUPERFAMILY SSF47973 1 151 3.79E-60 T 29-03-2018 IPR023798 Ribosomal protein S7 domain GBCGDNIH2_RS02820 1bc528a107b354a2e50b6e89eac3bc5e 158 Gene3D G3DSA:1.10.455.10 6 158 4.4E-60 T 29-03-2018 IPR023798 Ribosomal protein S7 domain GBCGDNIH2_RS02820 1bc528a107b354a2e50b6e89eac3bc5e 158 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 158 36.411 T 29-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 GBCGDNIH2_RS02820 1bc528a107b354a2e50b6e89eac3bc5e 158 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 29-03-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02820 1bc528a107b354a2e50b6e89eac3bc5e 158 PIRSF PIRSF002122 2 158 1.6E-59 T 29-03-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 GBCGDNIH2_RS12645 09b8df68a6b599f15fc98565536485ab 441 Pfam PF00588 SpoU rRNA Methylase family 296 435 2.2E-34 T 29-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 GBCGDNIH2_RS12645 09b8df68a6b599f15fc98565536485ab 441 Gene3D G3DSA:3.40.1280.10 279 440 7.7E-41 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal GBCGDNIH2_RS12645 09b8df68a6b599f15fc98565536485ab 441 SUPERFAMILY SSF55315 208 278 8.95E-9 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like GBCGDNIH2_RS12645 09b8df68a6b599f15fc98565536485ab 441 Gene3D G3DSA:3.30.1330.30 199 278 9.7E-8 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like GBCGDNIH2_RS12645 09b8df68a6b599f15fc98565536485ab 441 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 209 281 1.2E-7 T 29-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 GBCGDNIH2_RS12645 09b8df68a6b599f15fc98565536485ab 441 SMART SM00967 209 283 8.0E-13 T 29-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 GBCGDNIH2_RS12645 09b8df68a6b599f15fc98565536485ab 441 SUPERFAMILY SSF75217 272 439 4.91E-39 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases GBCGDNIH2_RS11505 2bac0ab4e5ec49385f794159d1fc08d1 259 Gene3D G3DSA:3.40.50.300 2 255 2.3E-64 T 29-03-2018 GBCGDNIH2_RS11505 2bac0ab4e5ec49385f794159d1fc08d1 259 SMART SM00382 30 231 1.3E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS11505 2bac0ab4e5ec49385f794159d1fc08d1 259 Pfam PF00005 ABC transporter 21 170 2.8E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GBCGDNIH2_RS11505 2bac0ab4e5ec49385f794159d1fc08d1 259 SUPERFAMILY SSF52540 4 237 7.53E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS11505 2bac0ab4e5ec49385f794159d1fc08d1 259 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GBCGDNIH2_RS01350 eb90b1f229ae65a28abfa6805c4f84aa 644 Gene3D G3DSA:3.30.300.30 513 622 1.7E-25 T 29-03-2018 GBCGDNIH2_RS01350 eb90b1f229ae65a28abfa6805c4f84aa 644 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 2 642 51.71 T 29-03-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 GBCGDNIH2_RS01350 eb90b1f229ae65a28abfa6805c4f84aa 644 Pfam PF00501 AMP-binding enzyme 83 519 2.9E-95 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 GBCGDNIH2_RS01350 eb90b1f229ae65a28abfa6805c4f84aa 644 SUPERFAMILY SSF56801 13 641 7.2E-182 T 29-03-2018 GBCGDNIH2_RS01350 eb90b1f229ae65a28abfa6805c4f84aa 644 Gene3D G3DSA:3.40.50.980 264 426 2.9E-36 T 29-03-2018 GBCGDNIH2_RS01350 eb90b1f229ae65a28abfa6805c4f84aa 644 ProSitePatterns PS00455 Putative AMP-binding domain signature. 258 269 - T 29-03-2018 IPR020845 AMP-binding, conserved site GBCGDNIH2_RS01350 eb90b1f229ae65a28abfa6805c4f84aa 644 Gene3D G3DSA:3.40.50.980 73 263 5.5E-50 T 29-03-2018 GBCGDNIH2_RS01350 eb90b1f229ae65a28abfa6805c4f84aa 644 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 23 640 1.4E-301 T 29-03-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 GBCGDNIH2_RS01350 eb90b1f229ae65a28abfa6805c4f84aa 644 Gene3D G3DSA:2.30.38.10 427 512 9.7E-15 T 29-03-2018 GBCGDNIH2_RS01350 eb90b1f229ae65a28abfa6805c4f84aa 644 Pfam PF13193 AMP-binding enzyme C-terminal domain 528 606 1.5E-26 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain GBCGDNIH2_RS01350 eb90b1f229ae65a28abfa6805c4f84aa 644 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 27 80 1.9E-13 T 29-03-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 GBCGDNIH2_RS10500 1050b256f42632e9f08086420d9f840c 305 Pfam PF01039 Carboxyl transferase domain 97 240 1.6E-16 T 29-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 GBCGDNIH2_RS10500 1050b256f42632e9f08086420d9f840c 305 SUPERFAMILY SSF52096 25 278 5.68E-79 T 29-03-2018 IPR029045 ClpP/crotonase-like domain GBCGDNIH2_RS10500 1050b256f42632e9f08086420d9f840c 305 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 1 280 4.9E-112 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 GBCGDNIH2_RS10500 1050b256f42632e9f08086420d9f840c 305 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 199 216 4.7E-37 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 GBCGDNIH2_RS10500 1050b256f42632e9f08086420d9f840c 305 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 128 142 4.7E-37 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 GBCGDNIH2_RS10500 1050b256f42632e9f08086420d9f840c 305 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 250 259 4.7E-37 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 GBCGDNIH2_RS10500 1050b256f42632e9f08086420d9f840c 305 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 228 239 4.7E-37 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 GBCGDNIH2_RS10500 1050b256f42632e9f08086420d9f840c 305 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 162 180 4.7E-37 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 GBCGDNIH2_RS10500 1050b256f42632e9f08086420d9f840c 305 Gene3D G3DSA:3.90.226.10 17 285 2.0E-63 T 29-03-2018 GBCGDNIH2_RS10500 1050b256f42632e9f08086420d9f840c 305 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 1 280 36.739 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 GBCGDNIH2_RS10165 337437145d77c8b305cc01729822cccc 414 Gene3D G3DSA:1.10.240.10 228 318 1.6E-30 T 29-03-2018 GBCGDNIH2_RS10165 337437145d77c8b305cc01729822cccc 414 Gene3D G3DSA:3.10.290.10 319 414 8.1E-20 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 GBCGDNIH2_RS10165 337437145d77c8b305cc01729822cccc 414 SUPERFAMILY SSF52374 7 323 1.05E-91 T 29-03-2018 GBCGDNIH2_RS10165 337437145d77c8b305cc01729822cccc 414 Pfam PF00579 tRNA synthetases class I (W and Y) 31 325 1.6E-75 T 29-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 GBCGDNIH2_RS10165 337437145d77c8b305cc01729822cccc 414 SUPERFAMILY SSF55174 333 412 6.04E-14 T 29-03-2018 GBCGDNIH2_RS10165 337437145d77c8b305cc01729822cccc 414 Gene3D G3DSA:3.40.50.620 6 227 9.1E-65 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GBCGDNIH2_RS10165 337437145d77c8b305cc01729822cccc 414 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 187 209 6.5E-26 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 GBCGDNIH2_RS10165 337437145d77c8b305cc01729822cccc 414 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 46 68 6.5E-26 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 GBCGDNIH2_RS10165 337437145d77c8b305cc01729822cccc 414 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 220 232 6.5E-26 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 GBCGDNIH2_RS10165 337437145d77c8b305cc01729822cccc 414 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 166 181 6.5E-26 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 GBCGDNIH2_RS10165 337437145d77c8b305cc01729822cccc 414 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 4 413 42.234 T 29-03-2018 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 GBCGDNIH2_RS10165 337437145d77c8b305cc01729822cccc 414 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 6 387 1.0E-107 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 GBCGDNIH2_RS05280 fc316e7b8205154b23e942115b26f411 284 Gene3D G3DSA:1.10.260.40 2 147 1.0E-16 T 29-03-2018 GBCGDNIH2_RS05280 fc316e7b8205154b23e942115b26f411 284 SUPERFAMILY SSF47413 3 65 8.85E-14 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GBCGDNIH2_RS05280 fc316e7b8205154b23e942115b26f411 284 SMART SM00530 9 63 4.3E-13 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 GBCGDNIH2_RS05280 fc316e7b8205154b23e942115b26f411 284 Pfam PF01381 Helix-turn-helix 10 60 1.3E-12 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 GBCGDNIH2_RS06710 5d78253a877762aa841625860c6c048e 119 PRINTS PR01853 Bacterial YajC preprotein translocase signature 22 42 2.2E-16 T 29-03-2018 IPR003849 Preprotein translocase YajC GBCGDNIH2_RS06710 5d78253a877762aa841625860c6c048e 119 PRINTS PR01853 Bacterial YajC preprotein translocase signature 60 78 2.2E-16 T 29-03-2018 IPR003849 Preprotein translocase YajC GBCGDNIH2_RS06710 5d78253a877762aa841625860c6c048e 119 Pfam PF02699 Preprotein translocase subunit 24 101 4.2E-27 T 29-03-2018 IPR003849 Preprotein translocase YajC GBCGDNIH2_RS06710 5d78253a877762aa841625860c6c048e 119 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 22 104 1.7E-25 T 29-03-2018 IPR003849 Preprotein translocase YajC GBCGDNIH2_RS06710 5d78253a877762aa841625860c6c048e 119 SMART SM01323 20 104 3.3E-39 T 29-03-2018 IPR003849 Preprotein translocase YajC GBCGDNIH2_RS11730 245e03080d38ad2800981cb0c3bf7956 88 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 3 49 1.2E-17 T 29-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 GBCGDNIH2_RS11730 245e03080d38ad2800981cb0c3bf7956 88 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 83 21.323 T 29-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 GBCGDNIH2_RS11730 245e03080d38ad2800981cb0c3bf7956 88 Pfam PF02416 mttA/Hcf106 family 4 50 1.8E-9 T 29-03-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 GBCGDNIH2_RS10910 aa5e9df5f0bd026387fef3e079945c8f 265 Pfam PF10014 2OG-Fe dioxygenase 71 261 4.9E-66 T 29-03-2018 IPR018724 2OG-Fe dioxygenase GBCGDNIH2_RS04045 1d4b07fd5668c3a6d6ce3ca9c98a8b8b 279 PIRSF PIRSF000097 6 122 4.2E-39 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 GBCGDNIH2_RS04045 1d4b07fd5668c3a6d6ce3ca9c98a8b8b 279 PIRSF PIRSF000097 118 278 6.4E-45 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 GBCGDNIH2_RS04045 1d4b07fd5668c3a6d6ce3ca9c98a8b8b 279 PRINTS PR00069 Aldo-keto reductase signature 98 116 1.5E-42 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 GBCGDNIH2_RS04045 1d4b07fd5668c3a6d6ce3ca9c98a8b8b 279 PRINTS PR00069 Aldo-keto reductase signature 42 66 1.5E-42 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 GBCGDNIH2_RS04045 1d4b07fd5668c3a6d6ce3ca9c98a8b8b 279 PRINTS PR00069 Aldo-keto reductase signature 164 193 1.5E-42 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 GBCGDNIH2_RS04045 1d4b07fd5668c3a6d6ce3ca9c98a8b8b 279 PRINTS PR00069 Aldo-keto reductase signature 201 225 1.5E-42 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 GBCGDNIH2_RS04045 1d4b07fd5668c3a6d6ce3ca9c98a8b8b 279 PRINTS PR00069 Aldo-keto reductase signature 130 147 1.5E-42 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 GBCGDNIH2_RS04045 1d4b07fd5668c3a6d6ce3ca9c98a8b8b 279 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 130 147 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 GBCGDNIH2_RS04045 1d4b07fd5668c3a6d6ce3ca9c98a8b8b 279 SUPERFAMILY SSF51430 13 272 1.24E-90 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain GBCGDNIH2_RS04045 1d4b07fd5668c3a6d6ce3ca9c98a8b8b 279 Gene3D G3DSA:3.20.20.100 2 279 1.0E-93 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain GBCGDNIH2_RS04045 1d4b07fd5668c3a6d6ce3ca9c98a8b8b 279 Pfam PF00248 Aldo/keto reductase family 30 265 1.0E-44 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain GBCGDNIH2_RS04370 f2a72a09b172c2c817759238d1f4a753 246 TIGRFAM TIGR01198 pgl: 6-phosphogluconolactonase 18 243 1.0E-57 T 29-03-2018 IPR005900 6-phosphogluconolactonase, DevB-type GO:0005975|GO:0006098|GO:0017057 KEGG: 00030+3.1.1.31 GBCGDNIH2_RS04370 f2a72a09b172c2c817759238d1f4a753 246 SUPERFAMILY SSF100950 13 244 1.79E-68 T 29-03-2018 GBCGDNIH2_RS04370 f2a72a09b172c2c817759238d1f4a753 246 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 19 236 1.2E-67 T 29-03-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 GBCGDNIH2_RS04370 f2a72a09b172c2c817759238d1f4a753 246 Gene3D G3DSA:3.40.50.1360 5 246 1.9E-72 T 29-03-2018 GBCGDNIH2_RS03680 cc15a24614ac17ec05ab7b5337f6fe84 294 Pfam PF03466 LysR substrate binding domain 87 289 1.2E-43 T 29-03-2018 IPR005119 LysR, substrate-binding GBCGDNIH2_RS03680 cc15a24614ac17ec05ab7b5337f6fe84 294 Gene3D G3DSA:1.10.10.10 1 92 1.5E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS03680 cc15a24614ac17ec05ab7b5337f6fe84 294 Gene3D G3DSA:3.40.190.10 93 174 1.7E-12 T 29-03-2018 GBCGDNIH2_RS03680 cc15a24614ac17ec05ab7b5337f6fe84 294 SUPERFAMILY SSF46785 1 111 1.97E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS03680 cc15a24614ac17ec05ab7b5337f6fe84 294 Gene3D G3DSA:3.40.190.10 175 257 4.0E-15 T 29-03-2018 GBCGDNIH2_RS03680 cc15a24614ac17ec05ab7b5337f6fe84 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 3.8E-23 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS03680 cc15a24614ac17ec05ab7b5337f6fe84 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 6.1E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS03680 cc15a24614ac17ec05ab7b5337f6fe84 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 6.1E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS03680 cc15a24614ac17ec05ab7b5337f6fe84 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 6.1E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS03680 cc15a24614ac17ec05ab7b5337f6fe84 294 SUPERFAMILY SSF53850 88 293 2.53E-45 T 29-03-2018 GBCGDNIH2_RS02925 440bd509028cb486768ada000de5553d 63 Pfam PF00327 Ribosomal protein L30p/L7e 4 54 1.2E-16 T 29-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain GBCGDNIH2_RS02925 440bd509028cb486768ada000de5553d 63 PIRSF PIRSF002211 1 60 1.4E-24 T 29-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS02925 440bd509028cb486768ada000de5553d 63 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 4 58 4.3E-23 T 29-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS02925 440bd509028cb486768ada000de5553d 63 Gene3D G3DSA:3.30.1390.20 4 58 1.9E-22 T 29-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain GBCGDNIH2_RS02925 440bd509028cb486768ada000de5553d 63 SUPERFAMILY SSF55129 1 59 3.92E-19 T 29-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain GBCGDNIH2_RS02925 440bd509028cb486768ada000de5553d 63 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 1 58 19.125 T 29-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS06960 ba4a48387d03d6d5c24e3c623da6220e 400 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 53 64 - T 29-03-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS06960 ba4a48387d03d6d5c24e3c623da6220e 400 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 130 400 2.3E-121 T 29-03-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS06960 ba4a48387d03d6d5c24e3c623da6220e 400 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 1 400 48.121 T 29-03-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS06960 ba4a48387d03d6d5c24e3c623da6220e 400 Gene3D G3DSA:1.10.645.10 219 389 5.4E-45 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS06960 ba4a48387d03d6d5c24e3c623da6220e 400 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 18 400 2.5E-177 T 29-03-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS06960 ba4a48387d03d6d5c24e3c623da6220e 400 Gene3D G3DSA:1.10.645.10 12 218 8.0E-62 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS06960 ba4a48387d03d6d5c24e3c623da6220e 400 SUPERFAMILY SSF56762 26 400 4.58E-139 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS07240 4f0fa6c60bf8f29427e7ef2b60a8dcf6 157 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 18 151 9.4E-40 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 GBCGDNIH2_RS07240 4f0fa6c60bf8f29427e7ef2b60a8dcf6 157 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 27 40 - T 29-03-2018 IPR019823 Large-conductance mechanosensitive channel, conserved site GBCGDNIH2_RS07240 4f0fa6c60bf8f29427e7ef2b60a8dcf6 157 SUPERFAMILY SSF81330 26 147 3.53E-33 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 GBCGDNIH2_RS07240 4f0fa6c60bf8f29427e7ef2b60a8dcf6 157 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 20 34 3.5E-9 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 GBCGDNIH2_RS07240 4f0fa6c60bf8f29427e7ef2b60a8dcf6 157 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 114 123 3.5E-9 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 GBCGDNIH2_RS07240 4f0fa6c60bf8f29427e7ef2b60a8dcf6 157 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 105 113 3.5E-9 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 GBCGDNIH2_RS07240 4f0fa6c60bf8f29427e7ef2b60a8dcf6 157 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 17 155 25.309 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 GBCGDNIH2_RS07240 4f0fa6c60bf8f29427e7ef2b60a8dcf6 157 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 18 152 2.8E-39 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 GBCGDNIH2_RS10490 8b14ba0b4820813d7450aef8ff03e514 108 Pfam PF00085 Thioredoxin 6 105 6.5E-33 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 GBCGDNIH2_RS10490 8b14ba0b4820813d7450aef8ff03e514 108 PRINTS PR00421 Thioredoxin family signature 72 83 1.0E-9 T 29-03-2018 GBCGDNIH2_RS10490 8b14ba0b4820813d7450aef8ff03e514 108 PRINTS PR00421 Thioredoxin family signature 24 32 1.0E-9 T 29-03-2018 GBCGDNIH2_RS10490 8b14ba0b4820813d7450aef8ff03e514 108 PRINTS PR00421 Thioredoxin family signature 32 41 1.0E-9 T 29-03-2018 GBCGDNIH2_RS10490 8b14ba0b4820813d7450aef8ff03e514 108 TIGRFAM TIGR01068 thioredoxin: thioredoxin 9 106 1.2E-37 T 29-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 GBCGDNIH2_RS10490 8b14ba0b4820813d7450aef8ff03e514 108 Gene3D G3DSA:3.40.30.10 1 107 1.5E-35 T 29-03-2018 GBCGDNIH2_RS10490 8b14ba0b4820813d7450aef8ff03e514 108 ProSitePatterns PS00194 Thioredoxin family active site. 25 43 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 GBCGDNIH2_RS10490 8b14ba0b4820813d7450aef8ff03e514 108 SUPERFAMILY SSF52833 4 106 1.6E-39 T 29-03-2018 IPR012336 Thioredoxin-like fold GBCGDNIH2_RS10490 8b14ba0b4820813d7450aef8ff03e514 108 PIRSF PIRSF000077 2 108 2.9E-42 T 29-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 GBCGDNIH2_RS06755 3b4f39097f7985a2c855b4a09ecaab9b 261 Pfam PF02616 Segregation and condensation protein ScpA 28 100 1.7E-7 T 29-03-2018 IPR003768 Segregation and condensation protein A GBCGDNIH2_RS06755 3b4f39097f7985a2c855b4a09ecaab9b 261 Gene3D G3DSA:1.10.10.580 173 244 1.4E-9 T 29-03-2018 GBCGDNIH2_RS03025 bde39e8097134c8d7325d0b036c7fc59 66 Pfam PF12073 Protein of unknown function (DUF3553) 10 59 1.7E-27 T 29-03-2018 IPR021938 Protein of unknown function DUF3553 GBCGDNIH2_RS11480 78c8184afd3a82ec15e893ad97095165 91 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 20 91 21.729 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS11480 78c8184afd3a82ec15e893ad97095165 91 ProSitePatterns PS00057 Ribosomal protein S18 signature. 39 62 - T 29-03-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS11480 78c8184afd3a82ec15e893ad97095165 91 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 39 89 2.0E-21 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS11480 78c8184afd3a82ec15e893ad97095165 91 Pfam PF01084 Ribosomal protein S18 37 86 9.8E-26 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS11480 78c8184afd3a82ec15e893ad97095165 91 SUPERFAMILY SSF46911 18 89 1.57E-27 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS11480 78c8184afd3a82ec15e893ad97095165 91 TIGRFAM TIGR00165 S18: ribosomal protein bS18 22 89 8.3E-30 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS11480 78c8184afd3a82ec15e893ad97095165 91 PRINTS PR00974 Ribosomal protein S18 family signature 46 56 1.3E-18 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS11480 78c8184afd3a82ec15e893ad97095165 91 PRINTS PR00974 Ribosomal protein S18 family signature 56 63 1.3E-18 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS11480 78c8184afd3a82ec15e893ad97095165 91 PRINTS PR00974 Ribosomal protein S18 family signature 64 78 1.3E-18 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS11480 78c8184afd3a82ec15e893ad97095165 91 PRINTS PR00974 Ribosomal protein S18 family signature 78 88 1.3E-18 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS11480 78c8184afd3a82ec15e893ad97095165 91 Gene3D G3DSA:4.10.640.10 4 91 9.2E-30 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS01145 6206fa35d4a495af685d605796b71d58 213 ProSitePatterns PS01064 Pyridoxamine 5'-phosphate oxidase signature. 183 196 - T 29-03-2018 IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 GBCGDNIH2_RS01145 6206fa35d4a495af685d605796b71d58 213 SUPERFAMILY SSF50475 16 213 4.71E-62 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 GBCGDNIH2_RS01145 6206fa35d4a495af685d605796b71d58 213 Gene3D G3DSA:2.30.110.10 6 213 1.1E-67 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 GBCGDNIH2_RS01145 6206fa35d4a495af685d605796b71d58 213 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 173 213 2.0E-15 T 29-03-2018 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 GBCGDNIH2_RS01145 6206fa35d4a495af685d605796b71d58 213 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 38 119 1.5E-22 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 GBCGDNIH2_RS01145 6206fa35d4a495af685d605796b71d58 213 Hamap MF_01629 Pyridoxine/pyridoxamine 5'-phosphate oxidase [pdxH]. 5 213 37.759 T 29-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 GBCGDNIH2_RS01145 6206fa35d4a495af685d605796b71d58 213 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 11 213 1.4E-71 T 29-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 GBCGDNIH2_RS01145 6206fa35d4a495af685d605796b71d58 213 PIRSF PIRSF000190 1 213 1.7E-72 T 29-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 GBCGDNIH2_RS03240 858f09bc8f16afc68648bdc517bfbcb3 324 SUPERFAMILY SSF46785 241 311 8.98E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS03240 858f09bc8f16afc68648bdc517bfbcb3 324 PIRSF PIRSF019423 14 323 1.8E-125 T 29-03-2018 IPR011213 Nicotinic acid mononucleotide biosynthesis protein GBCGDNIH2_RS03240 858f09bc8f16afc68648bdc517bfbcb3 324 SUPERFAMILY SSF55811 38 140 1.18E-8 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 GBCGDNIH2_RS03240 858f09bc8f16afc68648bdc517bfbcb3 324 Gene3D G3DSA:3.90.79.10 29 241 2.1E-25 T 29-03-2018 GBCGDNIH2_RS03240 858f09bc8f16afc68648bdc517bfbcb3 324 Gene3D G3DSA:1.10.10.10 242 314 1.0E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS05515 886a410ef4dbb89a99cb62481c0d2687 118 SUPERFAMILY SSF54913 4 106 8.9E-35 T 29-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta GBCGDNIH2_RS05515 886a410ef4dbb89a99cb62481c0d2687 118 Pfam PF03091 CutA1 divalent ion tolerance protein 7 103 2.3E-31 T 29-03-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 GBCGDNIH2_RS05515 886a410ef4dbb89a99cb62481c0d2687 118 Gene3D G3DSA:3.30.70.120 4 109 6.4E-34 T 29-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal GBCGDNIH2_RS02410 468dbe21116572c739f844f449d46de1 242 Pfam PF01569 PAP2 superfamily 128 222 1.9E-15 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase GBCGDNIH2_RS02410 468dbe21116572c739f844f449d46de1 242 Gene3D G3DSA:1.20.144.10 22 241 2.8E-32 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase GBCGDNIH2_RS02410 468dbe21116572c739f844f449d46de1 242 SMART SM00014 113 220 8.6E-8 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase GBCGDNIH2_RS02410 468dbe21116572c739f844f449d46de1 242 SUPERFAMILY SSF48317 45 233 9.03E-30 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase GBCGDNIH2_RS02410 468dbe21116572c739f844f449d46de1 242 PRINTS PR00483 Bacterial acid phosphatase class A signature 183 207 1.1E-8 T 29-03-2018 IPR001011 Acid phosphatase, class A, bacterial GO:0003993|GO:0030288 KEGG: 00740+3.1.3.2|MetaCyc: PWY-6348 GBCGDNIH2_RS02410 468dbe21116572c739f844f449d46de1 242 PRINTS PR00483 Bacterial acid phosphatase class A signature 151 177 1.1E-8 T 29-03-2018 IPR001011 Acid phosphatase, class A, bacterial GO:0003993|GO:0030288 KEGG: 00740+3.1.3.2|MetaCyc: PWY-6348 GBCGDNIH2_RS02410 468dbe21116572c739f844f449d46de1 242 PRINTS PR00483 Bacterial acid phosphatase class A signature 217 235 1.1E-8 T 29-03-2018 IPR001011 Acid phosphatase, class A, bacterial GO:0003993|GO:0030288 KEGG: 00740+3.1.3.2|MetaCyc: PWY-6348 GBCGDNIH2_RS02410 468dbe21116572c739f844f449d46de1 242 PIRSF PIRSF000897 1 237 1.9E-50 T 29-03-2018 IPR011158 Nonspecific acid phosphatase, class A GO:0003993|GO:0030288 KEGG: 00740+3.1.3.2|MetaCyc: PWY-6348 GBCGDNIH2_RS06730 ba17bb6935931566f9f9385b6a5e6ce9 273 PIRSF PIRSF000388 2 272 9.8E-100 T 29-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 GBCGDNIH2_RS06730 ba17bb6935931566f9f9385b6a5e6ce9 273 Pfam PF02548 Ketopantoate hydroxymethyltransferase 10 264 1.1E-101 T 29-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 GBCGDNIH2_RS06730 ba17bb6935931566f9f9385b6a5e6ce9 273 Gene3D G3DSA:3.20.20.60 4 269 5.0E-75 T 29-03-2018 GBCGDNIH2_RS06730 ba17bb6935931566f9f9385b6a5e6ce9 273 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 10 269 40.426 T 29-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 GBCGDNIH2_RS06730 ba17bb6935931566f9f9385b6a5e6ce9 273 SUPERFAMILY SSF51621 11 269 3.01E-96 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 GBCGDNIH2_RS06730 ba17bb6935931566f9f9385b6a5e6ce9 273 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 11 269 1.9E-93 T 29-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 GBCGDNIH2_RS05045 6bbe50e23d2edc9acdc4410af2b7016e 301 Pfam PF03466 LysR substrate binding domain 88 293 1.3E-40 T 29-03-2018 IPR005119 LysR, substrate-binding GBCGDNIH2_RS05045 6bbe50e23d2edc9acdc4410af2b7016e 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 1.5E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS05045 6bbe50e23d2edc9acdc4410af2b7016e 301 Gene3D G3DSA:3.40.190.10 177 265 7.0E-28 T 29-03-2018 GBCGDNIH2_RS05045 6bbe50e23d2edc9acdc4410af2b7016e 301 SUPERFAMILY SSF53850 89 298 9.59E-46 T 29-03-2018 GBCGDNIH2_RS05045 6bbe50e23d2edc9acdc4410af2b7016e 301 Gene3D G3DSA:1.10.10.10 3 83 4.1E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS05045 6bbe50e23d2edc9acdc4410af2b7016e 301 Gene3D G3DSA:3.40.190.10 92 176 1.3E-15 T 29-03-2018 GBCGDNIH2_RS05045 6bbe50e23d2edc9acdc4410af2b7016e 301 SUPERFAMILY SSF46785 4 86 4.23E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS10900 e372b17ef372a8437a5d7c240700435c 249 SMART SM00893 23 211 1.7E-69 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 GBCGDNIH2_RS10900 e372b17ef372a8437a5d7c240700435c 249 SUPERFAMILY SSF52402 1 242 3.42E-88 T 29-03-2018 GBCGDNIH2_RS10900 e372b17ef372a8437a5d7c240700435c 249 Gene3D G3DSA:3.40.50.620 1 248 6.0E-92 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GBCGDNIH2_RS10900 e372b17ef372a8437a5d7c240700435c 249 Pfam PF01012 Electron transfer flavoprotein domain 26 206 4.2E-49 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 GBCGDNIH2_RS10900 e372b17ef372a8437a5d7c240700435c 249 PIRSF PIRSF000090 1 249 9.0E-88 T 29-03-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 GBCGDNIH2_RS10900 e372b17ef372a8437a5d7c240700435c 249 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 155 175 - T 29-03-2018 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 GBCGDNIH2_RS04255 d4760aebecbd9076f63cb372816dee7b 282 Hamap MF_00056 2-dehydro-3-deoxyphosphooctonate aldolase [kdsA]. 20 282 51.248 T 29-03-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008152|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 GBCGDNIH2_RS04255 d4760aebecbd9076f63cb372816dee7b 282 Pfam PF00793 DAHP synthetase I family 17 277 6.2E-69 T 29-03-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 GBCGDNIH2_RS04255 d4760aebecbd9076f63cb372816dee7b 282 TIGRFAM TIGR01362 KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase 25 278 8.0E-117 T 29-03-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008152|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 GBCGDNIH2_RS04255 d4760aebecbd9076f63cb372816dee7b 282 Gene3D G3DSA:3.20.20.70 24 281 1.2E-72 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS04255 d4760aebecbd9076f63cb372816dee7b 282 SUPERFAMILY SSF51569 11 276 9.16E-105 T 29-03-2018 GBCGDNIH2_RS02700 9f3bc626e2aba13c85711a8b662866f0 387 SUPERFAMILY SSF53474 6 258 7.84E-62 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS02700 9f3bc626e2aba13c85711a8b662866f0 387 Pfam PF02627 Carboxymuconolactone decarboxylase family 296 378 1.1E-19 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 GBCGDNIH2_RS02700 9f3bc626e2aba13c85711a8b662866f0 387 Pfam PF00561 alpha/beta hydrolase fold 25 143 5.4E-22 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 GBCGDNIH2_RS02700 9f3bc626e2aba13c85711a8b662866f0 387 Gene3D G3DSA:3.40.50.1820 7 262 1.5E-52 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS02700 9f3bc626e2aba13c85711a8b662866f0 387 Gene3D G3DSA:1.20.1290.10 268 387 2.1E-29 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 GBCGDNIH2_RS02700 9f3bc626e2aba13c85711a8b662866f0 387 PRINTS PR00111 Alpha/beta hydrolase fold signature 205 219 2.0E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 GBCGDNIH2_RS02700 9f3bc626e2aba13c85711a8b662866f0 387 PRINTS PR00111 Alpha/beta hydrolase fold signature 108 121 2.0E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 GBCGDNIH2_RS02700 9f3bc626e2aba13c85711a8b662866f0 387 PRINTS PR00111 Alpha/beta hydrolase fold signature 94 107 2.0E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 GBCGDNIH2_RS02700 9f3bc626e2aba13c85711a8b662866f0 387 PRINTS PR00111 Alpha/beta hydrolase fold signature 50 65 2.0E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 GBCGDNIH2_RS02700 9f3bc626e2aba13c85711a8b662866f0 387 SUPERFAMILY SSF69118 266 381 7.2E-31 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 GBCGDNIH2_RS01655 49388002c7d4ab2a6577bdcd97c810b1 373 SMART SM00382 27 369 7.5E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS01655 49388002c7d4ab2a6577bdcd97c810b1 373 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 373 75.822 T 29-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 GBCGDNIH2_RS01655 49388002c7d4ab2a6577bdcd97c810b1 373 SUPERFAMILY SSF52540 247 356 7.25E-33 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS01655 49388002c7d4ab2a6577bdcd97c810b1 373 SUPERFAMILY SSF52540 7 215 7.25E-33 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS01655 49388002c7d4ab2a6577bdcd97c810b1 373 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 31 96 8.7E-9 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 GBCGDNIH2_RS01655 49388002c7d4ab2a6577bdcd97c810b1 373 Gene3D G3DSA:3.40.50.300 7 357 4.0E-25 T 29-03-2018 GBCGDNIH2_RS01655 49388002c7d4ab2a6577bdcd97c810b1 373 ProSitePatterns PS00617 RecF protein signature 1. 126 146 - T 29-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 GBCGDNIH2_RS10155 1d2bc2cb96cbd92aad19937e425faf64 221 SUPERFAMILY SSF53474 4 209 8.24E-49 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS10155 1d2bc2cb96cbd92aad19937e425faf64 221 Pfam PF00326 Prolyl oligopeptidase family 150 203 4.4E-6 T 29-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 GBCGDNIH2_RS10155 1d2bc2cb96cbd92aad19937e425faf64 221 Gene3D G3DSA:3.40.50.1820 2 216 1.5E-37 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS10155 1d2bc2cb96cbd92aad19937e425faf64 221 Pfam PF12146 Serine aminopeptidase, S33 37 133 1.7E-7 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 GBCGDNIH2_RS04350 386024a522c939a19fced0c9423d5e24 298 TIGRFAM TIGR02392 rpoH_proteo: alternative sigma factor RpoH 5 275 2.5E-112 T 29-03-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0008270|GO:0009408|GO:0016987 GBCGDNIH2_RS04350 386024a522c939a19fced0c9423d5e24 298 Pfam PF04542 Sigma-70 region 2 44 109 2.0E-16 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GBCGDNIH2_RS04350 386024a522c939a19fced0c9423d5e24 298 SUPERFAMILY SSF88946 4 112 2.04E-39 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GBCGDNIH2_RS04350 386024a522c939a19fced0c9423d5e24 298 Pfam PF00140 Sigma-70 factor, region 1.2 8 34 2.1E-10 T 29-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GBCGDNIH2_RS04350 386024a522c939a19fced0c9423d5e24 298 SUPERFAMILY SSF88659 181 276 2.43E-20 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GBCGDNIH2_RS04350 386024a522c939a19fced0c9423d5e24 298 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 244 270 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GBCGDNIH2_RS04350 386024a522c939a19fced0c9423d5e24 298 Hamap MF_00961 RNA polymerase sigma factor RpoH [rpoH]. 1 276 49.857 T 29-03-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0008270|GO:0009408|GO:0016987 GBCGDNIH2_RS04350 386024a522c939a19fced0c9423d5e24 298 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 40 274 3.7E-30 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GBCGDNIH2_RS04350 386024a522c939a19fced0c9423d5e24 298 Pfam PF04545 Sigma-70, region 4 221 272 3.9E-17 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GBCGDNIH2_RS04350 386024a522c939a19fced0c9423d5e24 298 PIRSF PIRSF000770 1 294 1.4E-41 T 29-03-2018 GBCGDNIH2_RS04350 386024a522c939a19fced0c9423d5e24 298 PRINTS PR00046 Major sigma-70 factor signature 225 237 1.6E-21 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GBCGDNIH2_RS04350 386024a522c939a19fced0c9423d5e24 298 PRINTS PR00046 Major sigma-70 factor signature 244 259 1.6E-21 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GBCGDNIH2_RS04350 386024a522c939a19fced0c9423d5e24 298 PRINTS PR00046 Major sigma-70 factor signature 92 100 1.6E-21 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GBCGDNIH2_RS04350 386024a522c939a19fced0c9423d5e24 298 PRINTS PR00046 Major sigma-70 factor signature 68 81 1.6E-21 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GBCGDNIH2_RS04350 386024a522c939a19fced0c9423d5e24 298 PRINTS PR00046 Major sigma-70 factor signature 259 270 1.6E-21 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GBCGDNIH2_RS04350 386024a522c939a19fced0c9423d5e24 298 Gene3D G3DSA:1.10.601.10 3 110 6.9E-38 T 29-03-2018 GBCGDNIH2_RS04350 386024a522c939a19fced0c9423d5e24 298 Gene3D G3DSA:1.10.10.10 216 292 6.4E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS09250 a1f3851df5ac0c856f14fc698f6b9ee8 779 Pfam PF03958 Bacterial type II/III secretion system short domain 198 253 8.1E-11 T 29-03-2018 IPR005644 NolW-like GBCGDNIH2_RS09250 a1f3851df5ac0c856f14fc698f6b9ee8 779 TIGRFAM TIGR02517 type_II_gspD: type II secretion system protein D 101 739 6.9E-121 T 29-03-2018 IPR013356 Type II secretion system GspD GO:0008565|GO:0015627|GO:0015628|GO:0019867 GBCGDNIH2_RS09250 a1f3851df5ac0c856f14fc698f6b9ee8 779 Pfam PF00263 Bacterial type II and III secretion system protein 565 729 5.8E-48 T 29-03-2018 IPR004846 Type II/III secretion system GO:0009306 GBCGDNIH2_RS09250 a1f3851df5ac0c856f14fc698f6b9ee8 779 PRINTS PR00811 Bacterial general secretion pathway protein D signature 694 712 6.4E-18 T 29-03-2018 IPR001775 GspD/PilQ family GBCGDNIH2_RS09250 a1f3851df5ac0c856f14fc698f6b9ee8 779 PRINTS PR00811 Bacterial general secretion pathway protein D signature 560 584 6.4E-18 T 29-03-2018 IPR001775 GspD/PilQ family GBCGDNIH2_RS09250 a1f3851df5ac0c856f14fc698f6b9ee8 779 PRINTS PR00811 Bacterial general secretion pathway protein D signature 717 731 6.4E-18 T 29-03-2018 IPR001775 GspD/PilQ family GBCGDNIH2_RS09250 a1f3851df5ac0c856f14fc698f6b9ee8 779 PRINTS PR00811 Bacterial general secretion pathway protein D signature 595 605 6.4E-18 T 29-03-2018 IPR001775 GspD/PilQ family GBCGDNIH2_RS09250 a1f3851df5ac0c856f14fc698f6b9ee8 779 PRINTS PR00811 Bacterial general secretion pathway protein D signature 490 500 6.4E-18 T 29-03-2018 IPR001775 GspD/PilQ family GBCGDNIH2_RS07475 20528f5d34660feb07ed11e717124898 405 Pfam PF02353 Mycolic acid cyclopropane synthetase 116 379 1.9E-81 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GBCGDNIH2_RS07475 20528f5d34660feb07ed11e717124898 405 PIRSF PIRSF003085 4 402 1.6E-125 T 29-03-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 GBCGDNIH2_RS07475 20528f5d34660feb07ed11e717124898 405 SUPERFAMILY SSF53335 123 384 1.34E-70 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GBCGDNIH2_RS07475 20528f5d34660feb07ed11e717124898 405 Gene3D G3DSA:3.40.50.150 110 384 3.0E-60 T 29-03-2018 GBCGDNIH2_RS11030 415016f19db09892168db3fc91107329 605 PRINTS PR00315 GTP-binding elongation factor signature 85 96 1.4E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GBCGDNIH2_RS11030 415016f19db09892168db3fc91107329 605 PRINTS PR00315 GTP-binding elongation factor signature 49 57 1.4E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GBCGDNIH2_RS11030 415016f19db09892168db3fc91107329 605 PRINTS PR00315 GTP-binding elongation factor signature 69 79 1.4E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GBCGDNIH2_RS11030 415016f19db09892168db3fc91107329 605 PRINTS PR00315 GTP-binding elongation factor signature 121 130 1.4E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GBCGDNIH2_RS11030 415016f19db09892168db3fc91107329 605 PRINTS PR00315 GTP-binding elongation factor signature 5 18 1.4E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GBCGDNIH2_RS11030 415016f19db09892168db3fc91107329 605 SUPERFAMILY SSF54980 301 386 1.65E-12 T 29-03-2018 IPR035647 EF-G domain III/V-like GBCGDNIH2_RS11030 415016f19db09892168db3fc91107329 605 Gene3D G3DSA:3.30.70.870 301 403 7.1E-30 T 29-03-2018 GBCGDNIH2_RS11030 415016f19db09892168db3fc91107329 605 Pfam PF00009 Elongation factor Tu GTP binding domain 2 192 2.0E-54 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GBCGDNIH2_RS11030 415016f19db09892168db3fc91107329 605 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 2 150 2.1E-24 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 GBCGDNIH2_RS11030 415016f19db09892168db3fc91107329 605 Gene3D G3DSA:2.40.30.10 191 299 6.9E-18 T 29-03-2018 GBCGDNIH2_RS11030 415016f19db09892168db3fc91107329 605 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 42 57 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site GBCGDNIH2_RS11030 415016f19db09892168db3fc91107329 605 SUPERFAMILY SSF50447 150 295 1.56E-26 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain GBCGDNIH2_RS11030 415016f19db09892168db3fc91107329 605 SUPERFAMILY SSF52540 2 205 3.15E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS11030 415016f19db09892168db3fc91107329 605 Gene3D G3DSA:2.40.50.250 482 571 8.1E-40 T 29-03-2018 GBCGDNIH2_RS11030 415016f19db09892168db3fc91107329 605 Gene3D G3DSA:3.40.50.300 66 190 2.8E-27 T 29-03-2018 GBCGDNIH2_RS11030 415016f19db09892168db3fc91107329 605 Gene3D G3DSA:3.30.70.240 404 481 8.2E-15 T 29-03-2018 GBCGDNIH2_RS11030 415016f19db09892168db3fc91107329 605 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 3 597 5.3E-283 T 29-03-2018 IPR006298 GTP-binding protein TypA GO:0005525 GBCGDNIH2_RS11030 415016f19db09892168db3fc91107329 605 Pfam PF03144 Elongation factor Tu domain 2 217 283 5.9E-9 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 GBCGDNIH2_RS11030 415016f19db09892168db3fc91107329 605 Gene3D G3DSA:3.40.50.300 1 65 1.6E-9 T 29-03-2018 GBCGDNIH2_RS11030 415016f19db09892168db3fc91107329 605 Pfam PF00679 Elongation factor G C-terminus 397 477 1.3E-19 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like GBCGDNIH2_RS11030 415016f19db09892168db3fc91107329 605 SUPERFAMILY SSF54980 397 511 1.2E-26 T 29-03-2018 IPR035647 EF-G domain III/V-like GBCGDNIH2_RS10065 66b17c8571317481edfcac4ae870569d 310 TIGRFAM TIGR02108 PQQ_syn_pqqB: coenzyme PQQ biosynthesis protein B 2 310 8.7E-121 T 29-03-2018 IPR011842 Coenzyme PQQ biosynthesis protein B GO:0006810|GO:0018189 GBCGDNIH2_RS10065 66b17c8571317481edfcac4ae870569d 310 SUPERFAMILY SSF56281 1 310 6.35E-53 T 29-03-2018 IPR001279 Metallo-beta-lactamase GBCGDNIH2_RS10065 66b17c8571317481edfcac4ae870569d 310 Gene3D G3DSA:3.60.15.10 1 310 1.7E-36 T 29-03-2018 IPR001279 Metallo-beta-lactamase GBCGDNIH2_RS10065 66b17c8571317481edfcac4ae870569d 310 Pfam PF12706 Beta-lactamase superfamily domain 51 277 2.7E-47 T 29-03-2018 IPR001279 Metallo-beta-lactamase GBCGDNIH2_RS10065 66b17c8571317481edfcac4ae870569d 310 Hamap MF_00653 Coenzyme PQQ synthesis protein B [pqqB]. 1 310 145.677 T 29-03-2018 IPR011842 Coenzyme PQQ biosynthesis protein B GO:0006810|GO:0018189 GBCGDNIH2_RS03175 ceaaa15efd6a98bb4cdab392a1d7fd5c 314 SUPERFAMILY SSF54534 161 249 7.85E-31 T 29-03-2018 GBCGDNIH2_RS03175 ceaaa15efd6a98bb4cdab392a1d7fd5c 314 SUPERFAMILY SSF109998 52 190 9.81E-15 T 29-03-2018 IPR027304 Trigger factor/SurA domain GBCGDNIH2_RS03175 ceaaa15efd6a98bb4cdab392a1d7fd5c 314 Pfam PF13616 PPIC-type PPIASE domain 157 251 1.9E-23 T 29-03-2018 GBCGDNIH2_RS03175 ceaaa15efd6a98bb4cdab392a1d7fd5c 314 Gene3D G3DSA:3.10.50.40 154 274 1.1E-37 T 29-03-2018 GBCGDNIH2_RS00540 c36e4872613f0209a2723f6babdcb0a2 332 SMART SM00849 75 257 1.2E-17 T 29-03-2018 IPR001279 Metallo-beta-lactamase GBCGDNIH2_RS00540 c36e4872613f0209a2723f6babdcb0a2 332 Pfam PF00753 Metallo-beta-lactamase superfamily 75 257 3.1E-22 T 29-03-2018 IPR001279 Metallo-beta-lactamase GBCGDNIH2_RS00540 c36e4872613f0209a2723f6babdcb0a2 332 Gene3D G3DSA:3.60.15.10 70 327 1.9E-24 T 29-03-2018 IPR001279 Metallo-beta-lactamase GBCGDNIH2_RS00540 c36e4872613f0209a2723f6babdcb0a2 332 SUPERFAMILY SSF56281 29 312 1.82E-46 T 29-03-2018 IPR001279 Metallo-beta-lactamase GBCGDNIH2_RS00540 c36e4872613f0209a2723f6babdcb0a2 332 TIGRFAM TIGR04559 SoxH_rel_PQQ_2: quinoprotein relay system zinc metallohydrolase 2 50 332 6.9E-109 T 29-03-2018 IPR030829 Quinoprotein relay system zinc metallohydrolase 2 GBCGDNIH2_RS04330 61e85b9a5ef34f5f0e7d09c4facbdf3a 297 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 20 295 1.8E-47 T 29-03-2018 IPR005218 Diacylglycerol/lipid kinase GBCGDNIH2_RS04330 61e85b9a5ef34f5f0e7d09c4facbdf3a 297 SUPERFAMILY SSF111331 10 296 9.32E-74 T 29-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain GBCGDNIH2_RS04330 61e85b9a5ef34f5f0e7d09c4facbdf3a 297 Gene3D G3DSA:3.40.50.10330 3 134 1.4E-30 T 29-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 GBCGDNIH2_RS04330 61e85b9a5ef34f5f0e7d09c4facbdf3a 297 Pfam PF00781 Diacylglycerol kinase catalytic domain 13 131 3.3E-27 T 29-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 GBCGDNIH2_RS04330 61e85b9a5ef34f5f0e7d09c4facbdf3a 297 SMART SM00046 12 134 5.5E-5 T 29-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 GBCGDNIH2_RS04225 8e7ae652d53afe4b61665228aad4ca69 153 Pfam PF04343 Protein of unknown function, DUF488 18 134 1.8E-26 T 29-03-2018 IPR007438 Protein of unknown function DUF488 GBCGDNIH2_RS04225 8e7ae652d53afe4b61665228aad4ca69 153 PIRSF PIRSF024492 2 152 8.0E-27 T 29-03-2018 IPR014519 Uncharacterised conserved protein UCP024492 GBCGDNIH2_RS06975 8bfd8ef4a8a0d64107b1fd2e2cb19c5a 121 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 24 120 2.8E-39 T 29-03-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS06975 8bfd8ef4a8a0d64107b1fd2e2cb19c5a 121 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 4 121 19.556 T 29-03-2018 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 GBCGDNIH2_RS01360 09c775d7d7f8a85d862003c6d73095f2 151 Pfam PF03918 Cytochrome C biogenesis protein 12 149 1.1E-48 T 29-03-2018 IPR005616 CcmH/CycL/Ccl2/NrfF family GBCGDNIH2_RS07225 5f495181989090967810045526c229ee 267 SUPERFAMILY SSF53474 13 261 3.06E-51 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS07225 5f495181989090967810045526c229ee 267 PRINTS PR00412 Epoxide hydrolase signature 84 97 2.9E-6 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 GBCGDNIH2_RS07225 5f495181989090967810045526c229ee 267 PRINTS PR00412 Epoxide hydrolase signature 237 259 2.9E-6 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 GBCGDNIH2_RS07225 5f495181989090967810045526c229ee 267 PRINTS PR00412 Epoxide hydrolase signature 98 111 2.9E-6 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 GBCGDNIH2_RS07225 5f495181989090967810045526c229ee 267 PRINTS PR00412 Epoxide hydrolase signature 41 56 2.9E-6 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 GBCGDNIH2_RS07225 5f495181989090967810045526c229ee 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 41 56 9.0E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 GBCGDNIH2_RS07225 5f495181989090967810045526c229ee 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 98 111 9.0E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 GBCGDNIH2_RS07225 5f495181989090967810045526c229ee 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 84 97 9.0E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 GBCGDNIH2_RS07225 5f495181989090967810045526c229ee 267 Gene3D G3DSA:3.40.50.1820 5 262 1.4E-45 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS07225 5f495181989090967810045526c229ee 267 Pfam PF00561 alpha/beta hydrolase fold 16 247 1.5E-22 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 GBCGDNIH2_RS09210 aef228b58421161d45d85494cca1a03a 403 Pfam PF00482 Type II secretion system (T2SS), protein F 69 191 2.1E-28 T 29-03-2018 IPR018076 Type II secretion system F domain GBCGDNIH2_RS09210 aef228b58421161d45d85494cca1a03a 403 Pfam PF00482 Type II secretion system (T2SS), protein F 272 392 1.2E-19 T 29-03-2018 IPR018076 Type II secretion system F domain GBCGDNIH2_RS09210 aef228b58421161d45d85494cca1a03a 403 PRINTS PR00812 Bacterial general secretion pathway protein F signature 163 191 2.3E-18 T 29-03-2018 IPR003004 GspF/PilC family GBCGDNIH2_RS09210 aef228b58421161d45d85494cca1a03a 403 PRINTS PR00812 Bacterial general secretion pathway protein F signature 64 76 2.3E-18 T 29-03-2018 IPR003004 GspF/PilC family GBCGDNIH2_RS09210 aef228b58421161d45d85494cca1a03a 403 PRINTS PR00812 Bacterial general secretion pathway protein F signature 382 401 2.3E-18 T 29-03-2018 IPR003004 GspF/PilC family GBCGDNIH2_RS09210 aef228b58421161d45d85494cca1a03a 403 PRINTS PR00812 Bacterial general secretion pathway protein F signature 366 380 2.3E-18 T 29-03-2018 IPR003004 GspF/PilC family GBCGDNIH2_RS03990 264f9c4702af870c82de99948b5dd0d6 299 SUPERFAMILY SSF53223 4 97 1.7E-30 T 29-03-2018 GBCGDNIH2_RS03990 264f9c4702af870c82de99948b5dd0d6 299 SUPERFAMILY SSF51735 113 233 1.99E-12 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS03990 264f9c4702af870c82de99948b5dd0d6 299 Pfam PF09176 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal 18 98 1.2E-32 T 29-03-2018 IPR015259 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal GBCGDNIH2_RS03990 264f9c4702af870c82de99948b5dd0d6 299 Gene3D G3DSA:3.40.50.10280 4 115 2.5E-47 T 29-03-2018 IPR015259 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal GBCGDNIH2_RS03990 264f9c4702af870c82de99948b5dd0d6 299 Gene3D G3DSA:3.40.50.720 116 237 5.3E-9 T 29-03-2018 GBCGDNIH2_RS09850 c5c3648d535827538814520f907dbc94 221 Pfam PF00717 Peptidase S24-like 135 170 5.6E-5 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C GBCGDNIH2_RS09850 c5c3648d535827538814520f907dbc94 221 SUPERFAMILY SSF51306 127 219 2.09E-8 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C GBCGDNIH2_RS09850 c5c3648d535827538814520f907dbc94 221 Gene3D G3DSA:2.10.109.10 109 221 3.2E-5 T 29-03-2018 GBCGDNIH2_RS10860 1ddc467971258356ee5635bb16d744e2 87 SUPERFAMILY SSF54285 6 85 1.87E-20 T 29-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp GBCGDNIH2_RS10860 1ddc467971258356ee5635bb16d744e2 87 Pfam PF02597 ThiS family 7 87 1.4E-15 T 29-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 GBCGDNIH2_RS10860 1ddc467971258356ee5635bb16d744e2 87 Gene3D G3DSA:3.10.20.30 5 87 2.5E-18 T 29-03-2018 IPR012675 Beta-grasp domain GBCGDNIH2_RS10860 1ddc467971258356ee5635bb16d744e2 87 TIGRFAM TIGR01682 moaD: molybdopterin converting factor, subunit 1 6 87 4.1E-20 T 29-03-2018 IPR010034 Molybdopterin converting factor, subunit 1 GO:0006777 Reactome: R-HSA-947581 GBCGDNIH2_RS06610 a00d5e2c60e1fda6a7cf7621199aa998 397 Pfam PF01565 FAD binding domain 9 151 2.0E-15 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 GBCGDNIH2_RS06610 a00d5e2c60e1fda6a7cf7621199aa998 397 Gene3D G3DSA:1.10.45.10 345 393 8.3E-4 T 29-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 GBCGDNIH2_RS06610 a00d5e2c60e1fda6a7cf7621199aa998 397 Gene3D G3DSA:3.30.465.10 58 189 7.8E-26 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 GBCGDNIH2_RS06610 a00d5e2c60e1fda6a7cf7621199aa998 397 SUPERFAMILY SSF56176 10 189 8.41E-31 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 GBCGDNIH2_RS06610 a00d5e2c60e1fda6a7cf7621199aa998 397 SUPERFAMILY SSF55103 213 394 2.35E-15 T 29-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 GBCGDNIH2_RS00790 6039313479a9e4c70f7565a8b2191e3e 145 Gene3D G3DSA:2.70.40.10 1 108 2.9E-45 T 29-03-2018 GBCGDNIH2_RS00790 6039313479a9e4c70f7565a8b2191e3e 145 TIGRFAM TIGR00576 dut: dUTP diphosphatase 6 145 8.2E-54 T 29-03-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|Reactome: R-HSA-499943 GBCGDNIH2_RS00790 6039313479a9e4c70f7565a8b2191e3e 145 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 1 145 32.5 T 29-03-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|Reactome: R-HSA-499943 GBCGDNIH2_RS00790 6039313479a9e4c70f7565a8b2191e3e 145 SUPERFAMILY SSF51283 2 145 8.9E-55 T 29-03-2018 IPR029054 dUTPase-like GBCGDNIH2_RS00790 6039313479a9e4c70f7565a8b2191e3e 145 Pfam PF00692 dUTPase 16 145 5.9E-31 T 29-03-2018 IPR029054 dUTPase-like GBCGDNIH2_RS00790 6039313479a9e4c70f7565a8b2191e3e 145 Gene3D G3DSA:2.70.40.10 109 145 2.0E-15 T 29-03-2018 GBCGDNIH2_RS09225 2f7bd8d5dd6a09c896243ab93f531684 205 Pfam PF07963 Prokaryotic N-terminal methylation motif 12 33 3.8E-7 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site GBCGDNIH2_RS09225 2f7bd8d5dd6a09c896243ab93f531684 205 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 12 32 5.3E-6 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site GBCGDNIH2_RS05965 3a5574a9e0d3b2017cd5b15a8a545524 241 Pfam PF01618 MotA/TolQ/ExbB proton channel family 92 223 1.0E-39 T 29-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 GBCGDNIH2_RS05965 3a5574a9e0d3b2017cd5b15a8a545524 241 TIGRFAM TIGR02796 tolQ: protein TolQ 21 235 3.5E-82 T 29-03-2018 IPR014163 Tol-Pal system, TolQ GO:0015031|GO:0016021 GBCGDNIH2_RS05965 3a5574a9e0d3b2017cd5b15a8a545524 241 Gene3D G3DSA:1.20.120.610 136 234 7.0E-5 T 29-03-2018 GBCGDNIH2_RS06965 dd6bf349d3e540e8a6caf7d723b0d243 228 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 95 153 2.0E-16 T 29-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS06965 dd6bf349d3e540e8a6caf7d723b0d243 228 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 45 166 2.6E-39 T 29-03-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS06965 dd6bf349d3e540e8a6caf7d723b0d243 228 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 47 167 3.1E-41 T 29-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS06965 dd6bf349d3e540e8a6caf7d723b0d243 228 SUPERFAMILY SSF143243 24 200 1.18E-54 T 29-03-2018 GBCGDNIH2_RS06965 dd6bf349d3e540e8a6caf7d723b0d243 228 Hamap MF_01357 NAD(P)H-quinone oxidoreductase subunit J, chloroplastic [ndhJ]. 24 174 30.268 T 29-03-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS06190 8882122fd6b23654ee87d17541eb598c 506 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 313 325 - T 29-03-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 GBCGDNIH2_RS06190 8882122fd6b23654ee87d17541eb598c 506 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 26 473 3.0E-190 T 29-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 GBCGDNIH2_RS06190 8882122fd6b23654ee87d17541eb598c 506 PIRSF PIRSF000130 17 506 4.8E-203 T 29-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 GBCGDNIH2_RS06190 8882122fd6b23654ee87d17541eb598c 506 Gene3D G3DSA:3.20.20.70 2 499 3.3E-119 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS06190 8882122fd6b23654ee87d17541eb598c 506 SMART SM01240 25 492 0.0 T 29-03-2018 GBCGDNIH2_RS06190 8882122fd6b23654ee87d17541eb598c 506 SUPERFAMILY SSF51412 235 496 3.01E-122 T 29-03-2018 GBCGDNIH2_RS06190 8882122fd6b23654ee87d17541eb598c 506 SUPERFAMILY SSF51412 23 108 3.01E-122 T 29-03-2018 GBCGDNIH2_RS06190 8882122fd6b23654ee87d17541eb598c 506 Pfam PF00571 CBS domain 169 222 8.3E-6 T 29-03-2018 IPR000644 CBS domain GBCGDNIH2_RS06190 8882122fd6b23654ee87d17541eb598c 506 Pfam PF00571 CBS domain 111 160 6.1E-11 T 29-03-2018 IPR000644 CBS domain GBCGDNIH2_RS06190 8882122fd6b23654ee87d17541eb598c 506 SUPERFAMILY SSF54631 81 222 4.17E-31 T 29-03-2018 GBCGDNIH2_RS06190 8882122fd6b23654ee87d17541eb598c 506 SMART SM00116 176 224 4.9E-6 T 29-03-2018 IPR000644 CBS domain GBCGDNIH2_RS06190 8882122fd6b23654ee87d17541eb598c 506 SMART SM00116 114 163 1.1E-10 T 29-03-2018 IPR000644 CBS domain GBCGDNIH2_RS06190 8882122fd6b23654ee87d17541eb598c 506 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 26 505 82.78 T 29-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 GBCGDNIH2_RS06190 8882122fd6b23654ee87d17541eb598c 506 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 26 492 3.3E-160 T 29-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 GBCGDNIH2_RS08515 57bea52630b42def06568abcd84b4422 365 Gene3D G3DSA:3.40.50.1820 10 248 4.9E-8 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS08515 57bea52630b42def06568abcd84b4422 365 SUPERFAMILY SSF53474 38 200 1.41E-9 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS12345 938cc4a1a67e665bf67a7c7c0f4f2a47 427 SUPERFAMILY SSF103473 34 408 1.31E-45 T 29-03-2018 IPR020846 Major facilitator superfamily domain GBCGDNIH2_RS12345 938cc4a1a67e665bf67a7c7c0f4f2a47 427 Pfam PF07690 Major Facilitator Superfamily 35 352 9.0E-33 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 GBCGDNIH2_RS12345 938cc4a1a67e665bf67a7c7c0f4f2a47 427 Gene3D G3DSA:1.20.1250.20 230 426 2.9E-14 T 29-03-2018 GBCGDNIH2_RS12345 938cc4a1a67e665bf67a7c7c0f4f2a47 427 Gene3D G3DSA:1.20.1250.20 30 229 9.8E-23 T 29-03-2018 GBCGDNIH2_RS12345 938cc4a1a67e665bf67a7c7c0f4f2a47 427 ProSitePatterns PS00216 Sugar transport proteins signature 1. 83 98 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 GBCGDNIH2_RS07855 a5de808346605f507c7c9f9a009c701b 273 SUPERFAMILY SSF53474 3 272 3.65E-62 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS07855 a5de808346605f507c7c9f9a009c701b 273 PRINTS PR00412 Epoxide hydrolase signature 47 62 6.0E-7 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 GBCGDNIH2_RS07855 a5de808346605f507c7c9f9a009c701b 273 PRINTS PR00412 Epoxide hydrolase signature 214 230 6.0E-7 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 GBCGDNIH2_RS07855 a5de808346605f507c7c9f9a009c701b 273 PRINTS PR00412 Epoxide hydrolase signature 27 45 6.0E-7 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 GBCGDNIH2_RS07855 a5de808346605f507c7c9f9a009c701b 273 Pfam PF00561 alpha/beta hydrolase fold 22 258 4.7E-26 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 GBCGDNIH2_RS07855 a5de808346605f507c7c9f9a009c701b 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 216 230 3.0E-11 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 GBCGDNIH2_RS07855 a5de808346605f507c7c9f9a009c701b 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 47 62 3.0E-11 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 GBCGDNIH2_RS07855 a5de808346605f507c7c9f9a009c701b 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 91 104 3.0E-11 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 GBCGDNIH2_RS07855 a5de808346605f507c7c9f9a009c701b 273 Gene3D G3DSA:3.40.50.1820 1 273 4.1E-56 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS10320 565079088b0909005ec2f049973352f1 863 SUPERFAMILY SSF82866 671 860 6.67E-21 T 29-03-2018 GBCGDNIH2_RS10320 565079088b0909005ec2f049973352f1 863 SUPERFAMILY SSF82866 250 432 1.7E-30 T 29-03-2018 GBCGDNIH2_RS10320 565079088b0909005ec2f049973352f1 863 Gene3D G3DSA:1.20.1640.10 663 861 1.2E-21 T 29-03-2018 GBCGDNIH2_RS10320 565079088b0909005ec2f049973352f1 863 Gene3D G3DSA:1.20.1640.10 228 438 6.1E-32 T 29-03-2018 GBCGDNIH2_RS10320 565079088b0909005ec2f049973352f1 863 TIGRFAM TIGR03480 HpnN: hopanoid biosynthesis associated RND transporter like protein HpnN 8 856 2.5E-292 T 29-03-2018 IPR017841 Hopanoid biosynthesis associated RND transporter-like protein HpnN GBCGDNIH2_RS10320 565079088b0909005ec2f049973352f1 863 Pfam PF03176 MMPL family 81 431 1.3E-19 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 GBCGDNIH2_RS10320 565079088b0909005ec2f049973352f1 863 Pfam PF03176 MMPL family 696 859 4.8E-6 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 GBCGDNIH2_RS04470 71d2db0affd6a685deab8884e6335b06 276 TIGRFAM TIGR00067 glut_race: glutamate racemase 8 223 1.7E-45 T 29-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GBCGDNIH2_RS04470 71d2db0affd6a685deab8884e6335b06 276 Gene3D G3DSA:3.40.50.1860 124 261 9.6E-22 T 29-03-2018 GBCGDNIH2_RS04470 71d2db0affd6a685deab8884e6335b06 276 Hamap MF_00258 Glutamate racemase [murI]. 6 264 26.418 T 29-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GBCGDNIH2_RS04470 71d2db0affd6a685deab8884e6335b06 276 SUPERFAMILY SSF53681 112 241 5.89E-25 T 29-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GBCGDNIH2_RS04470 71d2db0affd6a685deab8884e6335b06 276 Gene3D G3DSA:3.40.50.1860 4 123 2.2E-21 T 29-03-2018 GBCGDNIH2_RS04470 71d2db0affd6a685deab8884e6335b06 276 SUPERFAMILY SSF53681 7 107 4.25E-27 T 29-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GBCGDNIH2_RS04470 71d2db0affd6a685deab8884e6335b06 276 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 73 81 - T 29-03-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GBCGDNIH2_RS04470 71d2db0affd6a685deab8884e6335b06 276 Pfam PF01177 Asp/Glu/Hydantoin racemase 9 218 5.5E-19 T 29-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GBCGDNIH2_RS00865 38aa6b8f9bb3c807ac73f98183f8a70d 352 SUPERFAMILY SSF50998 37 349 5.23E-37 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily GBCGDNIH2_RS00865 38aa6b8f9bb3c807ac73f98183f8a70d 352 Gene3D G3DSA:2.80.10.50 16 109 5.0E-12 T 29-03-2018 GBCGDNIH2_RS00865 38aa6b8f9bb3c807ac73f98183f8a70d 352 Gene3D G3DSA:2.130.10.10 110 247 5.2E-19 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 GBCGDNIH2_RS00865 38aa6b8f9bb3c807ac73f98183f8a70d 352 SMART SM00320 265 305 110.0 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 GBCGDNIH2_RS00865 38aa6b8f9bb3c807ac73f98183f8a70d 352 SMART SM00320 220 258 11.0 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 GBCGDNIH2_RS00865 38aa6b8f9bb3c807ac73f98183f8a70d 352 SMART SM00320 308 347 11.0 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 GBCGDNIH2_RS00865 38aa6b8f9bb3c807ac73f98183f8a70d 352 SMART SM00320 56 95 0.54 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 GBCGDNIH2_RS00865 38aa6b8f9bb3c807ac73f98183f8a70d 352 SMART SM00320 139 176 0.046 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 GBCGDNIH2_RS00865 38aa6b8f9bb3c807ac73f98183f8a70d 352 SMART SM00320 96 137 35.0 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 GBCGDNIH2_RS00865 38aa6b8f9bb3c807ac73f98183f8a70d 352 Gene3D G3DSA:2.120.10.30 248 352 3.4E-14 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like GBCGDNIH2_RS00865 38aa6b8f9bb3c807ac73f98183f8a70d 352 Pfam PF00400 WD domain, G-beta repeat 140 175 0.13 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 GBCGDNIH2_RS10410 2f66224271c3335d7808afa77fc76320 254 SUPERFAMILY SSF53448 5 242 6.28E-51 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS10410 2f66224271c3335d7808afa77fc76320 254 Gene3D G3DSA:3.90.550.10 1 246 3.5E-40 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS10410 2f66224271c3335d7808afa77fc76320 254 Pfam PF02348 Cytidylyltransferase 5 217 4.6E-35 T 29-03-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 GBCGDNIH2_RS10410 2f66224271c3335d7808afa77fc76320 254 TIGRFAM TIGR00466 kdsB: 3-deoxy-D-manno-octulosonate cytidylyltransferase 3 236 5.6E-50 T 29-03-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 GBCGDNIH2_RS07055 94698e0c851d6959c9f516c9a57ea004 413 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 50 389 2.2E-73 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 GBCGDNIH2_RS07055 94698e0c851d6959c9f516c9a57ea004 413 SUPERFAMILY SSF111369 65 312 4.58E-56 T 29-03-2018 GBCGDNIH2_RS07055 94698e0c851d6959c9f516c9a57ea004 413 Gene3D G3DSA:1.20.1600.10 93 323 1.5E-23 T 29-03-2018 GBCGDNIH2_RS07055 94698e0c851d6959c9f516c9a57ea004 413 Pfam PF13533 Biotin-lipoyl like 75 123 2.7E-10 T 29-03-2018 GBCGDNIH2_RS05695 052adcf25c9b53ee76dcf26d9bd42fdc 204 SUPERFAMILY SSF55729 6 175 5.97E-35 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase GBCGDNIH2_RS05695 052adcf25c9b53ee76dcf26d9bd42fdc 204 Gene3D G3DSA:3.40.630.30 1 190 1.1E-26 T 29-03-2018 GBCGDNIH2_RS05695 052adcf25c9b53ee76dcf26d9bd42fdc 204 Pfam PF13302 Acetyltransferase (GNAT) domain 12 149 1.1E-11 T 29-03-2018 IPR000182 GNAT domain GO:0008080 GBCGDNIH2_RS01280 f7ab8b87e9493d6f2f49bea29e1b0fdf 79 Gene3D G3DSA:2.20.25.10 32 77 3.3E-20 T 29-03-2018 GBCGDNIH2_RS01280 f7ab8b87e9493d6f2f49bea29e1b0fdf 79 Pfam PF03966 Trm112p-like protein 26 65 5.3E-9 T 29-03-2018 IPR005651 Uncharacterised protein family UPF0434/Trm112 GBCGDNIH2_RS01280 f7ab8b87e9493d6f2f49bea29e1b0fdf 79 Hamap MF_01187 UPF0434 protein YcaR [ycaR]. 25 78 25.639 T 29-03-2018 IPR005651 Uncharacterised protein family UPF0434/Trm112 GBCGDNIH2_RS01280 f7ab8b87e9493d6f2f49bea29e1b0fdf 79 SUPERFAMILY SSF158997 25 78 7.85E-20 T 29-03-2018 GBCGDNIH2_RS01480 7c5cac3bd6d1b0acbfbd31786774f64d 133 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 127 3.3E-9 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain GBCGDNIH2_RS01480 7c5cac3bd6d1b0acbfbd31786774f64d 133 SUPERFAMILY SSF54593 4 130 1.51E-24 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase GBCGDNIH2_RS01480 7c5cac3bd6d1b0acbfbd31786774f64d 133 Gene3D G3DSA:3.10.180.10 9 133 2.2E-24 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase GBCGDNIH2_RS05325 92dd489e3393e8725ca14b1b1c2ba1ce 363 Gene3D G3DSA:1.20.1070.10 7 361 0.0011 T 29-03-2018 GBCGDNIH2_RS05325 92dd489e3393e8725ca14b1b1c2ba1ce 363 TIGRFAM TIGR00802 nico: transition metal uptake transporter, Ni2+-Co2+ transporter (NiCoT) family 59 338 1.0E-110 T 29-03-2018 IPR004688 Transition metal uptake transporter nickel/cobalt GO:0015099|GO:0016021|GO:0035444|GO:0046872 GBCGDNIH2_RS05325 92dd489e3393e8725ca14b1b1c2ba1ce 363 Pfam PF03824 High-affinity nickel-transport protein 56 343 6.3E-84 T 29-03-2018 IPR011541 Nickel/cobalt transporter, high-affinity GO:0015099|GO:0016021|GO:0035444|GO:0046872 GBCGDNIH2_RS11920 b8e98ec0b38a0b9766751ef1520de630 360 Gene3D G3DSA:1.10.540.10 2 107 5.1E-8 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 GBCGDNIH2_RS11920 b8e98ec0b38a0b9766751ef1520de630 360 SUPERFAMILY SSF56645 8 211 3.53E-27 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 GBCGDNIH2_RS11920 b8e98ec0b38a0b9766751ef1520de630 360 Gene3D G3DSA:2.40.110.10 118 212 1.7E-10 T 29-03-2018 GBCGDNIH2_RS06750 172baa9bc74c674ccb0ebc04f3216fe7 217 SUPERFAMILY SSF46785 81 156 4.54E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS06750 172baa9bc74c674ccb0ebc04f3216fe7 217 Gene3D G3DSA:1.10.10.10 2 82 4.8E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS06750 172baa9bc74c674ccb0ebc04f3216fe7 217 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 13 176 1.2E-31 T 29-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 GBCGDNIH2_RS06750 172baa9bc74c674ccb0ebc04f3216fe7 217 SUPERFAMILY SSF46785 6 79 1.24E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS06750 172baa9bc74c674ccb0ebc04f3216fe7 217 PIRSF PIRSF019345 1 202 2.0E-47 T 29-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 GBCGDNIH2_RS06750 172baa9bc74c674ccb0ebc04f3216fe7 217 Pfam PF04079 Segregation and condensation complex subunit ScpB 12 164 1.4E-49 T 29-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 GBCGDNIH2_RS06750 172baa9bc74c674ccb0ebc04f3216fe7 217 Gene3D G3DSA:1.10.10.10 83 173 2.7E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS00585 f84b6a9117a814162f65a00bcb9c0db0 286 SUPERFAMILY SSF56176 192 281 6.82E-19 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 GBCGDNIH2_RS00585 f84b6a9117a814162f65a00bcb9c0db0 286 Pfam PF03471 Transporter associated domain 195 275 7.0E-19 T 29-03-2018 IPR005170 Transporter-associated domain GBCGDNIH2_RS00585 f84b6a9117a814162f65a00bcb9c0db0 286 SUPERFAMILY SSF54631 56 198 1.83E-34 T 29-03-2018 GBCGDNIH2_RS00585 f84b6a9117a814162f65a00bcb9c0db0 286 Gene3D G3DSA:3.10.580.10 36 188 1.5E-34 T 29-03-2018 GBCGDNIH2_RS00585 f84b6a9117a814162f65a00bcb9c0db0 286 SMART SM00116 69 118 0.0019 T 29-03-2018 IPR000644 CBS domain GBCGDNIH2_RS00585 f84b6a9117a814162f65a00bcb9c0db0 286 SMART SM00116 131 179 2.4 T 29-03-2018 IPR000644 CBS domain GBCGDNIH2_RS00585 f84b6a9117a814162f65a00bcb9c0db0 286 Pfam PF00571 CBS domain 62 117 5.1E-6 T 29-03-2018 IPR000644 CBS domain GBCGDNIH2_RS00585 f84b6a9117a814162f65a00bcb9c0db0 286 Pfam PF00571 CBS domain 127 179 8.4E-7 T 29-03-2018 IPR000644 CBS domain GBCGDNIH2_RS00585 f84b6a9117a814162f65a00bcb9c0db0 286 Gene3D G3DSA:3.30.465.10 189 277 1.0E-23 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 GBCGDNIH2_RS00585 f84b6a9117a814162f65a00bcb9c0db0 286 SMART SM01091 194 277 3.0E-24 T 29-03-2018 IPR005170 Transporter-associated domain GBCGDNIH2_RS05460 ec1ca7ece81109dda08b207f46e847e2 431 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 13 429 52.964 T 29-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 GBCGDNIH2_RS05460 ec1ca7ece81109dda08b207f46e847e2 431 PIRSF PIRSF000412 3 431 1.4E-166 T 29-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 GBCGDNIH2_RS05460 ec1ca7ece81109dda08b207f46e847e2 431 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 228 244 - T 29-03-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 GBCGDNIH2_RS05460 ec1ca7ece81109dda08b207f46e847e2 431 SUPERFAMILY SSF53383 5 429 2.34E-179 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase GBCGDNIH2_RS05460 ec1ca7ece81109dda08b207f46e847e2 431 Pfam PF00464 Serine hydroxymethyltransferase 14 391 3.9E-177 T 29-03-2018 GBCGDNIH2_RS05460 ec1ca7ece81109dda08b207f46e847e2 431 Gene3D G3DSA:3.40.640.10 43 280 4.0E-52 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GBCGDNIH2_RS05460 ec1ca7ece81109dda08b207f46e847e2 431 Gene3D G3DSA:3.90.1150.10 281 428 1.1E-56 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 GBCGDNIH2_RS09825 cf761186a1b7129f265e9ddc6c9732b1 160 Pfam PF08534 Redoxin 4 157 2.6E-36 T 29-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 GBCGDNIH2_RS09825 cf761186a1b7129f265e9ddc6c9732b1 160 SUPERFAMILY SSF52833 1 157 1.7E-36 T 29-03-2018 IPR012336 Thioredoxin-like fold GBCGDNIH2_RS09825 cf761186a1b7129f265e9ddc6c9732b1 160 Gene3D G3DSA:3.40.30.10 1 160 2.2E-24 T 29-03-2018 GBCGDNIH2_RS11965 e707c048ebb41314c34560a3d8bad048 344 SUPERFAMILY SSF53335 7 336 3.32E-83 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GBCGDNIH2_RS11965 e707c048ebb41314c34560a3d8bad048 344 Pfam PF02636 Putative S-adenosyl-L-methionine-dependent methyltransferase 42 272 1.4E-55 T 29-03-2018 IPR003788 Protein arginine methyltransferase NDUFAF7 Reactome: R-HSA-6799198 GBCGDNIH2_RS11370 740e4bc2f97143e73d801bc440097944 278 Gene3D G3DSA:3.40.50.620 1 149 9.8E-9 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GBCGDNIH2_RS11370 740e4bc2f97143e73d801bc440097944 278 PRINTS PR01438 Universal stress protein signature 256 278 4.7E-7 T 29-03-2018 IPR006015 Universal stress protein A GBCGDNIH2_RS11370 740e4bc2f97143e73d801bc440097944 278 PRINTS PR01438 Universal stress protein signature 238 250 4.7E-7 T 29-03-2018 IPR006015 Universal stress protein A GBCGDNIH2_RS11370 740e4bc2f97143e73d801bc440097944 278 PRINTS PR01438 Universal stress protein signature 34 52 4.7E-7 T 29-03-2018 IPR006015 Universal stress protein A GBCGDNIH2_RS11370 740e4bc2f97143e73d801bc440097944 278 SUPERFAMILY SSF52402 1 150 7.95E-6 T 29-03-2018 GBCGDNIH2_RS11370 740e4bc2f97143e73d801bc440097944 278 SUPERFAMILY SSF52402 158 278 6.11E-20 T 29-03-2018 GBCGDNIH2_RS11370 740e4bc2f97143e73d801bc440097944 278 Gene3D G3DSA:3.40.50.620 150 278 2.7E-20 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GBCGDNIH2_RS11370 740e4bc2f97143e73d801bc440097944 278 Pfam PF00582 Universal stress protein family 218 276 1.2E-10 T 29-03-2018 IPR006016 UspA GO:0006950 GBCGDNIH2_RS08425 aed329e6b355d15be2cce16d32bb6d76 255 Pfam PF13560 Helix-turn-helix domain 20 72 2.4E-10 T 29-03-2018 GBCGDNIH2_RS08425 aed329e6b355d15be2cce16d32bb6d76 255 SUPERFAMILY SSF51306 121 233 4.06E-15 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C GBCGDNIH2_RS08425 aed329e6b355d15be2cce16d32bb6d76 255 Gene3D G3DSA:1.10.260.40 16 85 1.2E-13 T 29-03-2018 GBCGDNIH2_RS08425 aed329e6b355d15be2cce16d32bb6d76 255 SMART SM00530 22 76 3.4E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 GBCGDNIH2_RS08425 aed329e6b355d15be2cce16d32bb6d76 255 SUPERFAMILY SSF47413 15 76 1.15E-12 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GBCGDNIH2_RS08425 aed329e6b355d15be2cce16d32bb6d76 255 Gene3D G3DSA:2.10.109.10 127 251 4.2E-12 T 29-03-2018 GBCGDNIH2_RS08425 aed329e6b355d15be2cce16d32bb6d76 255 Pfam PF00717 Peptidase S24-like 165 236 6.5E-11 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C GBCGDNIH2_RS06115 ba89de5d95a3b7aa1818f026b35dc05d 185 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 12 123 6.9E-8 T 29-03-2018 IPR000014 PAS domain GBCGDNIH2_RS06115 ba89de5d95a3b7aa1818f026b35dc05d 185 Pfam PF13426 PAS domain 26 123 3.4E-13 T 29-03-2018 IPR000014 PAS domain GBCGDNIH2_RS06115 ba89de5d95a3b7aa1818f026b35dc05d 185 SUPERFAMILY SSF55785 25 123 3.14E-15 T 29-03-2018 IPR000014 PAS domain GBCGDNIH2_RS06115 ba89de5d95a3b7aa1818f026b35dc05d 185 Gene3D G3DSA:3.30.450.20 3 140 6.1E-15 T 29-03-2018 GBCGDNIH2_RS01895 754ee4196637e2fc76ef1e04f6a3ada2 129 Pfam PF10073 Uncharacterized protein conserved in bacteria (DUF2312) 57 128 1.7E-31 T 29-03-2018 IPR018753 Azospirillum phage Cd, Gp10 GBCGDNIH2_RS01895 754ee4196637e2fc76ef1e04f6a3ada2 129 Hamap MF_00797 UPF0335 protein . 52 129 20.354 T 29-03-2018 IPR018753 Azospirillum phage Cd, Gp10 GBCGDNIH2_RS03015 6aecd6ef2baa9ae19c4867d976889373 289 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 5 266 1.0E-102 T 29-03-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 GBCGDNIH2_RS03015 6aecd6ef2baa9ae19c4867d976889373 289 Gene3D G3DSA:3.90.550.10 1 279 5.8E-58 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS03015 6aecd6ef2baa9ae19c4867d976889373 289 Pfam PF00483 Nucleotidyl transferase 8 242 5.2E-26 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 GBCGDNIH2_RS03015 6aecd6ef2baa9ae19c4867d976889373 289 SUPERFAMILY SSF53448 6 277 6.93E-62 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS05865 0240cdf5778853e9102053483aab66e2 277 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 222 236 - T 29-03-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 GBCGDNIH2_RS05865 0240cdf5778853e9102053483aab66e2 277 Gene3D G3DSA:3.30.540.10 1 154 5.7E-44 T 29-03-2018 GBCGDNIH2_RS05865 0240cdf5778853e9102053483aab66e2 277 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 85 98 - T 29-03-2018 IPR020583 Inositol monophosphatase, metal-binding site GBCGDNIH2_RS05865 0240cdf5778853e9102053483aab66e2 277 SUPERFAMILY SSF56655 6 269 1.22E-79 T 29-03-2018 GBCGDNIH2_RS05865 0240cdf5778853e9102053483aab66e2 277 PRINTS PR01959 SuhB family inositol monophosphatase signature 167 193 1.5E-16 T 29-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 GBCGDNIH2_RS05865 0240cdf5778853e9102053483aab66e2 277 PRINTS PR01959 SuhB family inositol monophosphatase signature 209 221 1.5E-16 T 29-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 GBCGDNIH2_RS05865 0240cdf5778853e9102053483aab66e2 277 PRINTS PR01959 SuhB family inositol monophosphatase signature 21 43 1.5E-16 T 29-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 GBCGDNIH2_RS05865 0240cdf5778853e9102053483aab66e2 277 PRINTS PR01959 SuhB family inositol monophosphatase signature 113 132 1.5E-16 T 29-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 GBCGDNIH2_RS05865 0240cdf5778853e9102053483aab66e2 277 Gene3D G3DSA:3.40.190.80 155 277 1.3E-36 T 29-03-2018 GBCGDNIH2_RS05865 0240cdf5778853e9102053483aab66e2 277 PRINTS PR00377 Inositol monophosphatase superfamily signature 139 162 2.5E-56 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 GBCGDNIH2_RS05865 0240cdf5778853e9102053483aab66e2 277 PRINTS PR00377 Inositol monophosphatase superfamily signature 42 62 2.5E-56 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 GBCGDNIH2_RS05865 0240cdf5778853e9102053483aab66e2 277 PRINTS PR00377 Inositol monophosphatase superfamily signature 188 209 2.5E-56 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 GBCGDNIH2_RS05865 0240cdf5778853e9102053483aab66e2 277 PRINTS PR00377 Inositol monophosphatase superfamily signature 219 243 2.5E-56 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 GBCGDNIH2_RS05865 0240cdf5778853e9102053483aab66e2 277 PRINTS PR00377 Inositol monophosphatase superfamily signature 64 80 2.5E-56 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 GBCGDNIH2_RS05865 0240cdf5778853e9102053483aab66e2 277 PRINTS PR00377 Inositol monophosphatase superfamily signature 85 101 2.5E-56 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 GBCGDNIH2_RS05865 0240cdf5778853e9102053483aab66e2 277 Pfam PF00459 Inositol monophosphatase family 10 269 6.5E-59 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 GBCGDNIH2_RS12510 1bdbb94ccbec2b8fe663a5ad770bb488 818 PIRSF PIRSF000460 1 817 5.7E-222 T 29-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 GBCGDNIH2_RS12510 1bdbb94ccbec2b8fe663a5ad770bb488 818 TIGRFAM TIGR02093 P_ylase: glycogen/starch/alpha-glucan phosphorylases 13 811 0.0 T 29-03-2018 IPR011833 Glycogen/starch/alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 GBCGDNIH2_RS12510 1bdbb94ccbec2b8fe663a5ad770bb488 818 Gene3D G3DSA:3.40.50.2000 482 797 5.3E-128 T 29-03-2018 GBCGDNIH2_RS12510 1bdbb94ccbec2b8fe663a5ad770bb488 818 Pfam PF00343 Carbohydrate phosphorylase 103 811 2.5E-301 T 29-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 GBCGDNIH2_RS12510 1bdbb94ccbec2b8fe663a5ad770bb488 818 Gene3D G3DSA:3.40.50.2000 2 481 1.3E-180 T 29-03-2018 GBCGDNIH2_RS12510 1bdbb94ccbec2b8fe663a5ad770bb488 818 SUPERFAMILY SSF53756 9 816 0.0 T 29-03-2018 GBCGDNIH2_RS12510 1bdbb94ccbec2b8fe663a5ad770bb488 818 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 657 669 - T 29-03-2018 IPR035090 Phosphorylase pyridoxal-phosphate attachment site KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 GBCGDNIH2_RS07965 20bd29bc9fcc949c349d5f6a629d7687 496 SUPERFAMILY SSF53448 4 147 5.34E-9 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS07965 20bd29bc9fcc949c349d5f6a629d7687 496 Gene3D G3DSA:3.90.550.10 2 207 1.4E-4 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS07965 20bd29bc9fcc949c349d5f6a629d7687 496 Gene3D G3DSA:2.80.10.50 372 471 0.0017 T 29-03-2018 GBCGDNIH2_RS07965 20bd29bc9fcc949c349d5f6a629d7687 496 Pfam PF13704 Glycosyl transferase family 2 10 109 2.0E-14 T 29-03-2018 GBCGDNIH2_RS04000 0951501123be1ed9005864f96b084d8a 127 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 9 97 2.3E-25 T 29-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 GBCGDNIH2_RS04000 0951501123be1ed9005864f96b084d8a 127 SUPERFAMILY SSF55248 10 101 8.24E-27 T 29-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 GBCGDNIH2_RS04000 0951501123be1ed9005864f96b084d8a 127 Gene3D G3DSA:3.30.1360.20 2 102 1.2E-25 T 29-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 GBCGDNIH2_RS07105 2b2b4c6916dd1c87417bbc05296c021e 441 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 151 421 2.2E-80 T 29-03-2018 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 GBCGDNIH2_RS07105 2b2b4c6916dd1c87417bbc05296c021e 441 Pfam PF01458 Uncharacterized protein family (UPF0051) 186 407 3.1E-71 T 29-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 GBCGDNIH2_RS07105 2b2b4c6916dd1c87417bbc05296c021e 441 SUPERFAMILY SSF101960 38 431 3.14E-94 T 29-03-2018 GBCGDNIH2_RS05100 43050523bdefd52d72d0319f2d425802 244 Pfam PF01255 Putative undecaprenyl diphosphate synthase 20 240 9.5E-78 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 GBCGDNIH2_RS05100 43050523bdefd52d72d0319f2d425802 244 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 13 240 3.8E-82 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 GBCGDNIH2_RS05100 43050523bdefd52d72d0319f2d425802 244 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 186 203 - T 29-03-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199 GBCGDNIH2_RS05100 43050523bdefd52d72d0319f2d425802 244 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 13 241 39.519 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 GBCGDNIH2_RS05100 43050523bdefd52d72d0319f2d425802 244 Gene3D G3DSA:3.40.1180.10 5 244 3.3E-86 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 GBCGDNIH2_RS05100 43050523bdefd52d72d0319f2d425802 244 SUPERFAMILY SSF64005 11 236 5.75E-83 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 GBCGDNIH2_RS05350 dff28f1e47a7bfd03dffd536467e30f8 185 SUPERFAMILY SSF55083 21 179 2.09E-46 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 GBCGDNIH2_RS05350 dff28f1e47a7bfd03dffd536467e30f8 185 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 23 156 1.8E-33 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 GBCGDNIH2_RS05350 dff28f1e47a7bfd03dffd536467e30f8 185 Gene3D G3DSA:3.30.70.560 18 184 1.3E-48 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 GBCGDNIH2_RS05350 dff28f1e47a7bfd03dffd536467e30f8 185 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 24 156 9.5E-29 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 GBCGDNIH2_RS02060 84f6ff07f80ac4ba0229aed2619e1e94 604 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 296 588 3.9E-86 T 29-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 GBCGDNIH2_RS02060 84f6ff07f80ac4ba0229aed2619e1e94 604 SUPERFAMILY SSF51621 294 597 1.02E-88 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 GBCGDNIH2_RS02060 84f6ff07f80ac4ba0229aed2619e1e94 604 SUPERFAMILY SSF52009 163 285 4.32E-23 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 GBCGDNIH2_RS02060 84f6ff07f80ac4ba0229aed2619e1e94 604 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 335 354 5.4E-21 T 29-03-2018 GBCGDNIH2_RS02060 84f6ff07f80ac4ba0229aed2619e1e94 604 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 512 527 5.4E-21 T 29-03-2018 GBCGDNIH2_RS02060 84f6ff07f80ac4ba0229aed2619e1e94 604 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 495 510 5.4E-21 T 29-03-2018 GBCGDNIH2_RS02060 84f6ff07f80ac4ba0229aed2619e1e94 604 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 548 560 5.4E-21 T 29-03-2018 GBCGDNIH2_RS02060 84f6ff07f80ac4ba0229aed2619e1e94 604 Gene3D G3DSA:1.10.274.10 53 179 1.3E-20 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 GBCGDNIH2_RS02060 84f6ff07f80ac4ba0229aed2619e1e94 604 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 30 602 9.9E-124 T 29-03-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 GBCGDNIH2_RS02060 84f6ff07f80ac4ba0229aed2619e1e94 604 Pfam PF00391 PEP-utilising enzyme, mobile domain 189 267 2.1E-14 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 GBCGDNIH2_RS02060 84f6ff07f80ac4ba0229aed2619e1e94 604 Pfam PF05524 PEP-utilising enzyme, N-terminal 31 146 3.0E-20 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 GBCGDNIH2_RS02060 84f6ff07f80ac4ba0229aed2619e1e94 604 Gene3D G3DSA:3.20.20.60 292 603 1.2E-86 T 29-03-2018 GBCGDNIH2_RS02060 84f6ff07f80ac4ba0229aed2619e1e94 604 SUPERFAMILY SSF47831 54 177 3.14E-13 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 GBCGDNIH2_RS02060 84f6ff07f80ac4ba0229aed2619e1e94 604 PIRSF PIRSF000732 25 604 5.0E-188 T 29-03-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 GBCGDNIH2_RS02060 84f6ff07f80ac4ba0229aed2619e1e94 604 Gene3D G3DSA:3.50.30.10 180 285 4.6E-18 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 GBCGDNIH2_RS10100 ff6734dc0aa5a77116f31f8311b4c7f0 289 Pfam PF02634 FdhD/NarQ family 28 264 3.0E-77 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 GBCGDNIH2_RS10100 ff6734dc0aa5a77116f31f8311b4c7f0 289 SUPERFAMILY SSF53927 16 264 9.93E-78 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 GBCGDNIH2_RS10100 ff6734dc0aa5a77116f31f8311b4c7f0 289 Gene3D G3DSA:3.10.20.10 29 115 1.7E-20 T 29-03-2018 GBCGDNIH2_RS10100 ff6734dc0aa5a77116f31f8311b4c7f0 289 Gene3D G3DSA:3.40.140.10 129 269 9.7E-46 T 29-03-2018 GBCGDNIH2_RS10100 ff6734dc0aa5a77116f31f8311b4c7f0 289 PIRSF PIRSF015626 1 267 1.2E-77 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 GBCGDNIH2_RS10100 ff6734dc0aa5a77116f31f8311b4c7f0 289 Hamap MF_00187 Sulfurtransferase FdhD [fdhD]. 2 265 32.073 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 GBCGDNIH2_RS10100 ff6734dc0aa5a77116f31f8311b4c7f0 289 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 27 264 5.0E-60 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 GBCGDNIH2_RS12050 1f199a7ab8b179ec64a356d008aa608a 479 Pfam PF11870 Domain of unknown function (DUF3390) 404 462 6.0E-7 T 29-03-2018 IPR024569 4Fe-4S binding protein, C-terminal GBCGDNIH2_RS12050 1f199a7ab8b179ec64a356d008aa608a 479 Gene3D G3DSA:3.40.50.10420 135 295 1.6E-41 T 29-03-2018 GBCGDNIH2_RS12050 1f199a7ab8b179ec64a356d008aa608a 479 Gene3D G3DSA:3.40.50.10420 61 134 3.5E-7 T 29-03-2018 GBCGDNIH2_RS12050 1f199a7ab8b179ec64a356d008aa608a 479 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 314 325 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site GBCGDNIH2_RS12050 1f199a7ab8b179ec64a356d008aa608a 479 TIGRFAM TIGR00273 TIGR00273: iron-sulfur cluster-binding protein 17 455 3.7E-139 T 29-03-2018 IPR004452 4Fe-4S binding protein GO:0019516 GBCGDNIH2_RS12050 1f199a7ab8b179ec64a356d008aa608a 479 SUPERFAMILY SSF46548 279 396 1.92E-17 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 GBCGDNIH2_RS12050 1f199a7ab8b179ec64a356d008aa608a 479 Gene3D G3DSA:3.30.70.20 323 371 2.7E-9 T 29-03-2018 GBCGDNIH2_RS12050 1f199a7ab8b179ec64a356d008aa608a 479 SUPERFAMILY SSF100950 133 297 3.77E-39 T 29-03-2018 GBCGDNIH2_RS12050 1f199a7ab8b179ec64a356d008aa608a 479 SUPERFAMILY SSF100950 62 87 3.77E-39 T 29-03-2018 GBCGDNIH2_RS12050 1f199a7ab8b179ec64a356d008aa608a 479 Pfam PF12838 4Fe-4S dicluster domain 313 377 3.0E-6 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain GBCGDNIH2_RS12050 1f199a7ab8b179ec64a356d008aa608a 479 Gene3D G3DSA:3.30.70.20 296 322 0.0043 T 29-03-2018 GBCGDNIH2_RS12050 1f199a7ab8b179ec64a356d008aa608a 479 Pfam PF02589 LUD domain 68 296 1.4E-53 T 29-03-2018 IPR003741 LUD domain GBCGDNIH2_RS12050 1f199a7ab8b179ec64a356d008aa608a 479 Gene3D G3DSA:3.30.70.20 372 469 0.33 T 29-03-2018 GBCGDNIH2_RS00665 3ef4b13d89517ddabf38fff6f813917f 305 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GBCGDNIH2_RS00665 3ef4b13d89517ddabf38fff6f813917f 305 Gene3D G3DSA:3.40.50.300 1 247 6.2E-56 T 29-03-2018 GBCGDNIH2_RS00665 3ef4b13d89517ddabf38fff6f813917f 305 SUPERFAMILY SSF52540 36 240 3.45E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS00665 3ef4b13d89517ddabf38fff6f813917f 305 SMART SM00382 47 236 1.2E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS00665 3ef4b13d89517ddabf38fff6f813917f 305 Pfam PF00005 ABC transporter 38 185 1.1E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GBCGDNIH2_RS07485 31e60f5c7dacab87d5b3e2635127b3c0 346 Pfam PF10282 Lactonase, 7-bladed beta-propeller 108 308 4.8E-10 T 29-03-2018 IPR019405 Lactonase, 7-bladed beta propeller GBCGDNIH2_RS07485 31e60f5c7dacab87d5b3e2635127b3c0 346 Gene3D G3DSA:2.130.10.10 5 127 1.3E-16 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 GBCGDNIH2_RS07485 31e60f5c7dacab87d5b3e2635127b3c0 346 SUPERFAMILY SSF50974 14 330 1.26E-72 T 29-03-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 GBCGDNIH2_RS07485 31e60f5c7dacab87d5b3e2635127b3c0 346 Gene3D G3DSA:2.130.10.10 213 342 1.7E-25 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 GBCGDNIH2_RS07485 31e60f5c7dacab87d5b3e2635127b3c0 346 Gene3D G3DSA:2.130.10.10 128 212 5.8E-16 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 GBCGDNIH2_RS00200 26a102ca4a0cdde3f5f4f10b370e402d 144 Pfam PF02472 Biopolymer transport protein ExbD/TolR 19 139 1.4E-29 T 29-03-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS00200 26a102ca4a0cdde3f5f4f10b370e402d 144 TIGRFAM TIGR02803 ExbD_1: TonB system transport protein ExbD 19 140 3.5E-59 T 29-03-2018 IPR014170 TonB system transport protein ExbD type-1 GO:0006810|GO:0016020 GBCGDNIH2_RS12410 4e3eba07643455122b31bed13ce2a14f 219 SUPERFAMILY SSF64376 30 117 2.09E-22 T 29-03-2018 IPR007393 Domain of unknown function DUF448 GBCGDNIH2_RS12410 4e3eba07643455122b31bed13ce2a14f 219 Gene3D G3DSA:3.30.1230.10 22 115 5.0E-26 T 29-03-2018 IPR007393 Domain of unknown function DUF448 GBCGDNIH2_RS12410 4e3eba07643455122b31bed13ce2a14f 219 SUPERFAMILY SSF55315 114 198 4.32E-13 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like GBCGDNIH2_RS12410 4e3eba07643455122b31bed13ce2a14f 219 Gene3D G3DSA:3.30.1330.30 116 205 2.0E-12 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like GBCGDNIH2_RS12410 4e3eba07643455122b31bed13ce2a14f 219 Pfam PF04296 Protein of unknown function (DUF448) 33 108 6.2E-19 T 29-03-2018 IPR007393 Domain of unknown function DUF448 GBCGDNIH2_RS12070 76498c1b98a28e235f3f9781b1a4d7c5 384 SMART SM00925 128 282 1.1E-89 T 29-03-2018 IPR005300 Lytic transglycosylase MltA, domain B GO:0004553 GBCGDNIH2_RS12070 76498c1b98a28e235f3f9781b1a4d7c5 384 SUPERFAMILY SSF50685 8 382 2.06E-126 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain GBCGDNIH2_RS12070 76498c1b98a28e235f3f9781b1a4d7c5 384 Gene3D G3DSA:2.40.40.10 19 136 1.1E-12 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain GBCGDNIH2_RS12070 76498c1b98a28e235f3f9781b1a4d7c5 384 PIRSF PIRSF019422 1 384 4.0E-127 T 29-03-2018 IPR026044 Membrane-bound lytic murein transglycosylase A GBCGDNIH2_RS12070 76498c1b98a28e235f3f9781b1a4d7c5 384 Pfam PF06725 3D domain 305 378 5.5E-25 T 29-03-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 GBCGDNIH2_RS12070 76498c1b98a28e235f3f9781b1a4d7c5 384 Pfam PF03562 MltA specific insert domain 38 282 1.9E-82 T 29-03-2018 IPR005300 Lytic transglycosylase MltA, domain B GO:0004553 GBCGDNIH2_RS12070 76498c1b98a28e235f3f9781b1a4d7c5 384 Gene3D G3DSA:2.40.240.50 137 285 3.6E-61 T 29-03-2018 GBCGDNIH2_RS02720 f38cf5c20c5ec877b8e2b65f2cf1de6e 512 Gene3D G3DSA:3.30.70.870 371 443 2.6E-11 T 29-03-2018 GBCGDNIH2_RS02720 f38cf5c20c5ec877b8e2b65f2cf1de6e 512 Pfam PF00009 Elongation factor Tu GTP binding domain 10 251 1.1E-48 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GBCGDNIH2_RS02720 f38cf5c20c5ec877b8e2b65f2cf1de6e 512 Gene3D G3DSA:2.40.30.10 243 361 3.6E-16 T 29-03-2018 GBCGDNIH2_RS02720 f38cf5c20c5ec877b8e2b65f2cf1de6e 512 SUPERFAMILY SSF54980 369 442 2.34E-15 T 29-03-2018 IPR035647 EF-G domain III/V-like GBCGDNIH2_RS02720 f38cf5c20c5ec877b8e2b65f2cf1de6e 512 Pfam PF16658 Class II release factor RF3, C-terminal domain 364 490 3.2E-43 T 29-03-2018 IPR032090 Peptide chain release factor 3, C-terminal GBCGDNIH2_RS02720 f38cf5c20c5ec877b8e2b65f2cf1de6e 512 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 228 250 5.5E-10 T 29-03-2018 GBCGDNIH2_RS02720 f38cf5c20c5ec877b8e2b65f2cf1de6e 512 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 121 144 5.5E-10 T 29-03-2018 GBCGDNIH2_RS02720 f38cf5c20c5ec877b8e2b65f2cf1de6e 512 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 15 156 3.5E-22 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 GBCGDNIH2_RS02720 f38cf5c20c5ec877b8e2b65f2cf1de6e 512 Gene3D G3DSA:3.40.50.300 79 242 6.5E-26 T 29-03-2018 GBCGDNIH2_RS02720 f38cf5c20c5ec877b8e2b65f2cf1de6e 512 Gene3D G3DSA:3.40.50.300 1 78 1.4E-7 T 29-03-2018 GBCGDNIH2_RS02720 f38cf5c20c5ec877b8e2b65f2cf1de6e 512 SUPERFAMILY SSF52540 7 254 1.93E-80 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS02720 f38cf5c20c5ec877b8e2b65f2cf1de6e 512 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 56 71 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site GBCGDNIH2_RS02720 f38cf5c20c5ec877b8e2b65f2cf1de6e 512 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 2 503 47.546 T 29-03-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 GBCGDNIH2_RS02720 f38cf5c20c5ec877b8e2b65f2cf1de6e 512 PRINTS PR00315 GTP-binding elongation factor signature 13 26 4.9E-12 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GBCGDNIH2_RS02720 f38cf5c20c5ec877b8e2b65f2cf1de6e 512 PRINTS PR00315 GTP-binding elongation factor signature 99 110 4.9E-12 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GBCGDNIH2_RS02720 f38cf5c20c5ec877b8e2b65f2cf1de6e 512 PRINTS PR00315 GTP-binding elongation factor signature 63 71 4.9E-12 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GBCGDNIH2_RS02720 f38cf5c20c5ec877b8e2b65f2cf1de6e 512 PRINTS PR00315 GTP-binding elongation factor signature 83 93 4.9E-12 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GBCGDNIH2_RS02720 f38cf5c20c5ec877b8e2b65f2cf1de6e 512 PRINTS PR00315 GTP-binding elongation factor signature 135 144 4.9E-12 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GBCGDNIH2_RS02720 f38cf5c20c5ec877b8e2b65f2cf1de6e 512 SUPERFAMILY SSF50447 238 368 4.24E-25 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain GBCGDNIH2_RS03565 26db9eba5b2fd340243c88508a7cb728 235 TIGRFAM TIGR04409 LptC_YrbK: LPS export ABC transporter periplasmic protein LptC 46 198 4.2E-11 T 29-03-2018 IPR026265 Lipopolysaccharide export system protein LptC GO:0005887|GO:0015221|GO:0015920 GBCGDNIH2_RS03565 26db9eba5b2fd340243c88508a7cb728 235 Pfam PF06835 Lipopolysaccharide-assembly, LptC-related 88 197 1.3E-8 T 29-03-2018 IPR010664 Lipopolysaccharide assembly, LptC-related GBCGDNIH2_RS11250 8371bae44db46c983ae3608440cf9c98 236 Pfam PF01730 UreF 47 193 2.3E-34 T 29-03-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 GBCGDNIH2_RS11250 8371bae44db46c983ae3608440cf9c98 236 PIRSF PIRSF009467 13 236 1.1E-60 T 29-03-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 GBCGDNIH2_RS11250 8371bae44db46c983ae3608440cf9c98 236 Hamap MF_01385 Urease accessory protein UreF [ureF]. 15 236 30.678 T 29-03-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 GBCGDNIH2_RS05420 6c2ae90cadf84da6fac0d91cef8390ef 339 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 255 267 - T 29-03-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 GBCGDNIH2_RS05420 6c2ae90cadf84da6fac0d91cef8390ef 339 PIRSF PIRSF001415 1 339 3.8E-145 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 GBCGDNIH2_RS05420 6c2ae90cadf84da6fac0d91cef8390ef 339 Gene3D G3DSA:3.20.20.70 1 339 5.5E-146 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS05420 6c2ae90cadf84da6fac0d91cef8390ef 339 Pfam PF00490 Delta-aminolevulinic acid dehydratase 9 334 6.6E-139 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 GBCGDNIH2_RS05420 6c2ae90cadf84da6fac0d91cef8390ef 339 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 310 329 6.1E-45 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 GBCGDNIH2_RS05420 6c2ae90cadf84da6fac0d91cef8390ef 339 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 126 140 6.1E-45 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 GBCGDNIH2_RS05420 6c2ae90cadf84da6fac0d91cef8390ef 339 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 202 221 6.1E-45 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 GBCGDNIH2_RS05420 6c2ae90cadf84da6fac0d91cef8390ef 339 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 255 271 6.1E-45 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 GBCGDNIH2_RS05420 6c2ae90cadf84da6fac0d91cef8390ef 339 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 280 295 6.1E-45 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 GBCGDNIH2_RS05420 6c2ae90cadf84da6fac0d91cef8390ef 339 SUPERFAMILY SSF51569 5 338 6.01E-139 T 29-03-2018 GBCGDNIH2_RS05420 6c2ae90cadf84da6fac0d91cef8390ef 339 SMART SM01004 6 336 1.1E-233 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 GBCGDNIH2_RS05495 73c9cbe71cae5053ec312f29a656c03b 107 SUPERFAMILY SSF47729 4 94 1.62E-25 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 GBCGDNIH2_RS05495 73c9cbe71cae5053ec312f29a656c03b 107 TIGRFAM TIGR00987 himA: integration host factor, alpha subunit 3 90 1.8E-37 T 29-03-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 GBCGDNIH2_RS05495 73c9cbe71cae5053ec312f29a656c03b 107 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 49 68 - T 29-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 GBCGDNIH2_RS05495 73c9cbe71cae5053ec312f29a656c03b 107 Gene3D G3DSA:4.10.520.10 2 97 2.4E-24 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 GBCGDNIH2_RS05495 73c9cbe71cae5053ec312f29a656c03b 107 Pfam PF00216 Bacterial DNA-binding protein 4 91 5.7E-25 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 GBCGDNIH2_RS05495 73c9cbe71cae5053ec312f29a656c03b 107 SMART SM00411 4 93 6.8E-29 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 GBCGDNIH2_RS05495 73c9cbe71cae5053ec312f29a656c03b 107 Hamap MF_00380 Integration host factor subunit alpha [ihfA]. 2 98 25.566 T 29-03-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 GBCGDNIH2_RS05495 73c9cbe71cae5053ec312f29a656c03b 107 PRINTS PR01727 Prokaryotic integration host factor signature 77 91 8.5E-13 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 GBCGDNIH2_RS05495 73c9cbe71cae5053ec312f29a656c03b 107 PRINTS PR01727 Prokaryotic integration host factor signature 43 58 8.5E-13 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 GBCGDNIH2_RS05495 73c9cbe71cae5053ec312f29a656c03b 107 PRINTS PR01727 Prokaryotic integration host factor signature 61 74 8.5E-13 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 GBCGDNIH2_RS01750 e5e5f211c255e73719296e748dcd8ab5 203 SUPERFAMILY SSF102405 12 190 5.49E-58 T 29-03-2018 GBCGDNIH2_RS01750 e5e5f211c255e73719296e748dcd8ab5 203 Gene3D G3DSA:3.40.50.450 6 197 2.2E-54 T 29-03-2018 GBCGDNIH2_RS01750 e5e5f211c255e73719296e748dcd8ab5 203 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 15 191 5.0E-55 T 29-03-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG GBCGDNIH2_RS01750 e5e5f211c255e73719296e748dcd8ab5 203 Pfam PF03641 Possible lysine decarboxylase 59 188 1.5E-36 T 29-03-2018 IPR031100 LOG family GBCGDNIH2_RS02480 9ed38120a3a2526d6a9ec2863c1aba78 181 Gene3D G3DSA:3.90.45.10 1 180 8.2E-56 T 29-03-2018 IPR023635 Peptide deformylase GBCGDNIH2_RS02480 9ed38120a3a2526d6a9ec2863c1aba78 181 Pfam PF01327 Polypeptide deformylase 4 156 3.1E-44 T 29-03-2018 IPR023635 Peptide deformylase GBCGDNIH2_RS02480 9ed38120a3a2526d6a9ec2863c1aba78 181 Hamap MF_00163 Peptide deformylase [def]. 2 168 26.03 T 29-03-2018 IPR023635 Peptide deformylase GBCGDNIH2_RS02480 9ed38120a3a2526d6a9ec2863c1aba78 181 PRINTS PR01576 Peptide deformylase signature 107 125 2.0E-27 T 29-03-2018 IPR023635 Peptide deformylase GBCGDNIH2_RS02480 9ed38120a3a2526d6a9ec2863c1aba78 181 PRINTS PR01576 Peptide deformylase signature 34 63 2.0E-27 T 29-03-2018 IPR023635 Peptide deformylase GBCGDNIH2_RS02480 9ed38120a3a2526d6a9ec2863c1aba78 181 PRINTS PR01576 Peptide deformylase signature 95 106 2.0E-27 T 29-03-2018 IPR023635 Peptide deformylase GBCGDNIH2_RS02480 9ed38120a3a2526d6a9ec2863c1aba78 181 PRINTS PR01576 Peptide deformylase signature 126 155 2.0E-27 T 29-03-2018 IPR023635 Peptide deformylase GBCGDNIH2_RS02480 9ed38120a3a2526d6a9ec2863c1aba78 181 PIRSF PIRSF004749 1 180 1.1E-47 T 29-03-2018 IPR023635 Peptide deformylase GBCGDNIH2_RS02480 9ed38120a3a2526d6a9ec2863c1aba78 181 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 5 165 3.0E-35 T 29-03-2018 IPR023635 Peptide deformylase GBCGDNIH2_RS02480 9ed38120a3a2526d6a9ec2863c1aba78 181 SUPERFAMILY SSF56420 3 168 5.36E-55 T 29-03-2018 IPR023635 Peptide deformylase GBCGDNIH2_RS11885 1cc249c89eafe68a2f58947a30a8ccbb 465 Gene3D G3DSA:3.40.50.300 246 374 6.0E-18 T 29-03-2018 GBCGDNIH2_RS11885 1cc249c89eafe68a2f58947a30a8ccbb 465 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 198 362 9.1E-25 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 GBCGDNIH2_RS11885 1cc249c89eafe68a2f58947a30a8ccbb 465 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 4 128 3.5E-21 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 GBCGDNIH2_RS11885 1cc249c89eafe68a2f58947a30a8ccbb 465 Gene3D G3DSA:3.30.300.20 375 457 2.3E-35 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta GBCGDNIH2_RS11885 1cc249c89eafe68a2f58947a30a8ccbb 465 Gene3D G3DSA:1.20.120.430 67 245 1.8E-35 T 29-03-2018 GBCGDNIH2_RS11885 1cc249c89eafe68a2f58947a30a8ccbb 465 Pfam PF01926 50S ribosome-binding GTPase 201 318 2.0E-21 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 GBCGDNIH2_RS11885 1cc249c89eafe68a2f58947a30a8ccbb 465 Pfam PF01926 50S ribosome-binding GTPase 4 119 2.8E-27 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 GBCGDNIH2_RS11885 1cc249c89eafe68a2f58947a30a8ccbb 465 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 201 221 2.3E-5 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 GBCGDNIH2_RS11885 1cc249c89eafe68a2f58947a30a8ccbb 465 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 250 265 2.3E-5 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 GBCGDNIH2_RS11885 1cc249c89eafe68a2f58947a30a8ccbb 465 Hamap MF_00195 GTPase Der [der]. 1 459 36.873 T 29-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 GBCGDNIH2_RS11885 1cc249c89eafe68a2f58947a30a8ccbb 465 SUPERFAMILY SSF52540 137 167 8.14E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS11885 1cc249c89eafe68a2f58947a30a8ccbb 465 SUPERFAMILY SSF52540 196 463 8.14E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS11885 1cc249c89eafe68a2f58947a30a8ccbb 465 Gene3D G3DSA:1.20.120.430 2 66 5.3E-17 T 29-03-2018 GBCGDNIH2_RS11885 1cc249c89eafe68a2f58947a30a8ccbb 465 SUPERFAMILY SSF52540 4 165 4.18E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS11885 1cc249c89eafe68a2f58947a30a8ccbb 465 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 376 456 1.6E-32 T 29-03-2018 IPR032859 GTPase Der, C-terminal KH-domain-like GBCGDNIH2_RS11885 1cc249c89eafe68a2f58947a30a8ccbb 465 PIRSF PIRSF006485 1 464 8.4E-160 T 29-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 GBCGDNIH2_RS11885 1cc249c89eafe68a2f58947a30a8ccbb 465 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 2 456 2.9E-161 T 29-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 GBCGDNIH2_RS11550 a4dbb8ed83e1628a5d3f60ba0e82c3fc 159 Gene3D G3DSA:1.10.287.1080 41 133 4.3E-18 T 29-03-2018 GBCGDNIH2_RS11550 a4dbb8ed83e1628a5d3f60ba0e82c3fc 159 SUPERFAMILY SSF101386 44 132 4.11E-22 T 29-03-2018 GBCGDNIH2_RS11550 a4dbb8ed83e1628a5d3f60ba0e82c3fc 159 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 45 128 2.5E-26 T 29-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 GBCGDNIH2_RS11550 a4dbb8ed83e1628a5d3f60ba0e82c3fc 159 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 42 128 19.236 T 29-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 GBCGDNIH2_RS11550 a4dbb8ed83e1628a5d3f60ba0e82c3fc 159 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 48 131 1.6E-16 T 29-03-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 GBCGDNIH2_RS05585 333e7b920e3e6d798815ea7f58e5ded2 429 PRINTS PR00083 Histidinol dehydrogenase signature 200 225 1.5E-78 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 GBCGDNIH2_RS05585 333e7b920e3e6d798815ea7f58e5ded2 429 PRINTS PR00083 Histidinol dehydrogenase signature 170 196 1.5E-78 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 GBCGDNIH2_RS05585 333e7b920e3e6d798815ea7f58e5ded2 429 PRINTS PR00083 Histidinol dehydrogenase signature 136 162 1.5E-78 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 GBCGDNIH2_RS05585 333e7b920e3e6d798815ea7f58e5ded2 429 PRINTS PR00083 Histidinol dehydrogenase signature 229 250 1.5E-78 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 GBCGDNIH2_RS05585 333e7b920e3e6d798815ea7f58e5ded2 429 PRINTS PR00083 Histidinol dehydrogenase signature 320 345 1.5E-78 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 GBCGDNIH2_RS05585 333e7b920e3e6d798815ea7f58e5ded2 429 PRINTS PR00083 Histidinol dehydrogenase signature 251 270 1.5E-78 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 GBCGDNIH2_RS05585 333e7b920e3e6d798815ea7f58e5ded2 429 PRINTS PR00083 Histidinol dehydrogenase signature 361 379 1.5E-78 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 GBCGDNIH2_RS05585 333e7b920e3e6d798815ea7f58e5ded2 429 PRINTS PR00083 Histidinol dehydrogenase signature 33 57 1.5E-78 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 GBCGDNIH2_RS05585 333e7b920e3e6d798815ea7f58e5ded2 429 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 5 427 41.204 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 GBCGDNIH2_RS05585 333e7b920e3e6d798815ea7f58e5ded2 429 PIRSF PIRSF000099 1 429 3.0E-157 T 29-03-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 GBCGDNIH2_RS05585 333e7b920e3e6d798815ea7f58e5ded2 429 Gene3D G3DSA:3.40.50.1980 226 371 5.8E-64 T 29-03-2018 GBCGDNIH2_RS05585 333e7b920e3e6d798815ea7f58e5ded2 429 Pfam PF00815 Histidinol dehydrogenase 23 427 1.1E-164 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 GBCGDNIH2_RS05585 333e7b920e3e6d798815ea7f58e5ded2 429 Gene3D G3DSA:3.40.50.1980 26 225 1.1E-84 T 29-03-2018 GBCGDNIH2_RS05585 333e7b920e3e6d798815ea7f58e5ded2 429 SUPERFAMILY SSF53720 28 427 2.75E-81 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 GBCGDNIH2_RS05585 333e7b920e3e6d798815ea7f58e5ded2 429 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 229 261 - T 29-03-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 GBCGDNIH2_RS05585 333e7b920e3e6d798815ea7f58e5ded2 429 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 33 426 6.9E-159 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 GBCGDNIH2_RS12080 6a8f1f66cff12f0973cf12b4f12af40b 184 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 2 160 2.0E-29 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 GBCGDNIH2_RS12080 6a8f1f66cff12f0973cf12b4f12af40b 184 SMART SM00855 2 157 5.0E-9 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 GBCGDNIH2_RS12080 6a8f1f66cff12f0973cf12b4f12af40b 184 Gene3D G3DSA:3.40.50.1240 1 173 2.3E-37 T 29-03-2018 IPR029033 Histidine phosphatase superfamily GBCGDNIH2_RS12080 6a8f1f66cff12f0973cf12b4f12af40b 184 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 3 12 - T 29-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 GBCGDNIH2_RS12080 6a8f1f66cff12f0973cf12b4f12af40b 184 SUPERFAMILY SSF53254 2 174 3.14E-35 T 29-03-2018 IPR029033 Histidine phosphatase superfamily GBCGDNIH2_RS09795 e8a0f303bc4fa5d8f02ba01af6344c8d 281 Pfam PF06707 Protein of unknown function (DUF1194) 40 240 3.0E-54 T 29-03-2018 IPR010607 Protein of unknown function DUF1194 GBCGDNIH2_RS09795 e8a0f303bc4fa5d8f02ba01af6344c8d 281 Gene3D G3DSA:3.40.50.410 29 239 9.3E-14 T 29-03-2018 IPR002035 von Willebrand factor, type A GBCGDNIH2_RS09795 e8a0f303bc4fa5d8f02ba01af6344c8d 281 SUPERFAMILY SSF53300 40 238 8.73E-19 T 29-03-2018 IPR002035 von Willebrand factor, type A GBCGDNIH2_RS04525 27b17bf0acf76f52afdb950808a36bb6 282 Gene3D G3DSA:3.40.50.150 16 202 1.6E-31 T 29-03-2018 GBCGDNIH2_RS04525 27b17bf0acf76f52afdb950808a36bb6 282 SUPERFAMILY SSF53335 16 239 2.08E-46 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GBCGDNIH2_RS04525 27b17bf0acf76f52afdb950808a36bb6 282 Pfam PF04072 Leucine carboxyl methyltransferase 23 176 1.4E-9 T 29-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 GBCGDNIH2_RS04280 d5857c6a2ab1e10d701d1dc7cad35ee6 685 SMART SM00490 489 572 2.0E-16 T 29-03-2018 IPR001650 Helicase, C-terminal GBCGDNIH2_RS04280 d5857c6a2ab1e10d701d1dc7cad35ee6 685 Pfam PF00270 DEAD/DEAH box helicase 285 416 9.2E-16 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 GBCGDNIH2_RS04280 d5857c6a2ab1e10d701d1dc7cad35ee6 685 Gene3D G3DSA:2.40.50.140 50 141 8.9E-7 T 29-03-2018 GBCGDNIH2_RS04280 d5857c6a2ab1e10d701d1dc7cad35ee6 685 Pfam PF00271 Helicase conserved C-terminal domain 465 571 3.9E-14 T 29-03-2018 IPR001650 Helicase, C-terminal GBCGDNIH2_RS04280 d5857c6a2ab1e10d701d1dc7cad35ee6 685 Gene3D G3DSA:3.40.50.300 442 613 1.8E-21 T 29-03-2018 GBCGDNIH2_RS04280 d5857c6a2ab1e10d701d1dc7cad35ee6 685 SUPERFAMILY SSF52540 198 437 1.02E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS04280 d5857c6a2ab1e10d701d1dc7cad35ee6 685 Gene3D G3DSA:3.40.50.300 243 441 1.6E-30 T 29-03-2018 GBCGDNIH2_RS04280 d5857c6a2ab1e10d701d1dc7cad35ee6 685 SUPERFAMILY SSF50249 8 174 2.4E-17 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold GBCGDNIH2_RS04280 d5857c6a2ab1e10d701d1dc7cad35ee6 685 SMART SM00487 257 444 4.6E-23 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain GBCGDNIH2_RS04280 d5857c6a2ab1e10d701d1dc7cad35ee6 685 SUPERFAMILY SSF52540 284 334 5.33E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS04280 d5857c6a2ab1e10d701d1dc7cad35ee6 685 SUPERFAMILY SSF52540 488 634 5.33E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS09815 418f9442702266607399410f5535540b 319 SUPERFAMILY SSF56112 5 310 6.56E-80 T 29-03-2018 IPR011009 Protein kinase-like domain GBCGDNIH2_RS09815 418f9442702266607399410f5535540b 319 Pfam PF01636 Phosphotransferase enzyme family 28 254 2.1E-34 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase GBCGDNIH2_RS09815 418f9442702266607399410f5535540b 319 TIGRFAM TIGR00938 thrB_alt: homoserine kinase 1 307 8.2E-114 T 29-03-2018 IPR005280 Homoserine kinase, type II GO:0004413|GO:0009088 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 GBCGDNIH2_RS09815 418f9442702266607399410f5535540b 319 Gene3D G3DSA:3.90.1200.10 106 315 2.9E-28 T 29-03-2018 GBCGDNIH2_RS09815 418f9442702266607399410f5535540b 319 Hamap MF_00301 Homoserine kinase [thrB]. 1 319 160.19 T 29-03-2018 IPR005280 Homoserine kinase, type II GO:0004413|GO:0009088 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 GBCGDNIH2_RS09815 418f9442702266607399410f5535540b 319 Gene3D G3DSA:3.30.200.20 1 104 8.2E-23 T 29-03-2018 GBCGDNIH2_RS05265 0bf5ee2a71e11d0d1ad75c5524b8e5cd 404 Gene3D G3DSA:3.90.1150.10 272 404 4.8E-36 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 GBCGDNIH2_RS05265 0bf5ee2a71e11d0d1ad75c5524b8e5cd 404 SUPERFAMILY SSF53383 18 400 3.2E-90 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase GBCGDNIH2_RS05265 0bf5ee2a71e11d0d1ad75c5524b8e5cd 404 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 20 399 4.5E-95 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 GBCGDNIH2_RS05265 0bf5ee2a71e11d0d1ad75c5524b8e5cd 404 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 213 227 - T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 GBCGDNIH2_RS05265 0bf5ee2a71e11d0d1ad75c5524b8e5cd 404 Gene3D G3DSA:3.40.640.10 17 271 4.3E-43 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GBCGDNIH2_RS05265 0bf5ee2a71e11d0d1ad75c5524b8e5cd 404 PIRSF PIRSF001434 8 403 2.3E-117 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 GBCGDNIH2_RS05265 0bf5ee2a71e11d0d1ad75c5524b8e5cd 404 TIGRFAM TIGR01324 cysta_beta_ly_B: cystathionine beta-lyase 21 401 2.0E-132 T 29-03-2018 IPR006233 Cystathionine beta-lyase, bacterial GO:0004121|GO:0005737|GO:0006520 KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936 GBCGDNIH2_RS07115 9c19b0b86e631e0e0370007655974323 498 Pfam PF01458 Uncharacterized protein family (UPF0051) 236 469 1.0E-68 T 29-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 GBCGDNIH2_RS07115 9c19b0b86e631e0e0370007655974323 498 SUPERFAMILY SSF101960 39 495 1.44E-139 T 29-03-2018 GBCGDNIH2_RS07115 9c19b0b86e631e0e0370007655974323 498 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 19 489 2.4E-189 T 29-03-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 GBCGDNIH2_RS03915 c03c1f228c0be0cfb5168ec2bce5548e 688 Gene3D G3DSA:3.60.120.10 272 675 1.7E-146 T 29-03-2018 IPR005801 ADC synthase GO:0009058 GBCGDNIH2_RS03915 c03c1f228c0be0cfb5168ec2bce5548e 688 TIGRFAM TIGR00553 pabB: aminodeoxychorismate synthase, component I 320 662 2.2E-105 T 29-03-2018 IPR005802 Para-aminobenzoate synthase, component I GO:0009396 KEGG: 00790+2.6.1.85|MetaCyc: PWY-6543 GBCGDNIH2_RS03915 c03c1f228c0be0cfb5168ec2bce5548e 688 Pfam PF00425 chorismate binding enzyme 406 660 1.4E-91 T 29-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal GBCGDNIH2_RS03915 c03c1f228c0be0cfb5168ec2bce5548e 688 PRINTS PR00097 Anthranilate synthase component II signature 172 185 1.0E-30 T 29-03-2018 GBCGDNIH2_RS03915 c03c1f228c0be0cfb5168ec2bce5548e 688 PRINTS PR00097 Anthranilate synthase component II signature 82 93 1.0E-30 T 29-03-2018 GBCGDNIH2_RS03915 c03c1f228c0be0cfb5168ec2bce5548e 688 PRINTS PR00097 Anthranilate synthase component II signature 3 17 1.0E-30 T 29-03-2018 GBCGDNIH2_RS03915 c03c1f228c0be0cfb5168ec2bce5548e 688 PRINTS PR00097 Anthranilate synthase component II signature 107 115 1.0E-30 T 29-03-2018 GBCGDNIH2_RS03915 c03c1f228c0be0cfb5168ec2bce5548e 688 PRINTS PR00097 Anthranilate synthase component II signature 127 139 1.0E-30 T 29-03-2018 GBCGDNIH2_RS03915 c03c1f228c0be0cfb5168ec2bce5548e 688 PRINTS PR00097 Anthranilate synthase component II signature 54 63 1.0E-30 T 29-03-2018 GBCGDNIH2_RS03915 c03c1f228c0be0cfb5168ec2bce5548e 688 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 4 192 1.0E-42 T 29-03-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 GBCGDNIH2_RS03915 c03c1f228c0be0cfb5168ec2bce5548e 688 Gene3D G3DSA:3.40.50.880 1 199 6.3E-50 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like GBCGDNIH2_RS03915 c03c1f228c0be0cfb5168ec2bce5548e 688 SUPERFAMILY SSF56322 231 668 1.7E-129 T 29-03-2018 IPR005801 ADC synthase GO:0009058 GBCGDNIH2_RS03915 c03c1f228c0be0cfb5168ec2bce5548e 688 Pfam PF04715 Anthranilate synthase component I, N terminal region 245 364 7.8E-13 T 29-03-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 GBCGDNIH2_RS03915 c03c1f228c0be0cfb5168ec2bce5548e 688 SUPERFAMILY SSF52317 1 198 5.47E-47 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like GBCGDNIH2_RS03915 c03c1f228c0be0cfb5168ec2bce5548e 688 Pfam PF00117 Glutamine amidotransferase class-I 5 192 1.6E-37 T 29-03-2018 IPR017926 Glutamine amidotransferase GBCGDNIH2_RS03915 c03c1f228c0be0cfb5168ec2bce5548e 688 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 51 65 9.6E-6 T 29-03-2018 GBCGDNIH2_RS03915 c03c1f228c0be0cfb5168ec2bce5548e 688 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 82 98 9.6E-6 T 29-03-2018 GBCGDNIH2_RS03915 c03c1f228c0be0cfb5168ec2bce5548e 688 PRINTS PR00096 Glutamine amidotransferase superfamily signature 54 63 2.6E-12 T 29-03-2018 GBCGDNIH2_RS03915 c03c1f228c0be0cfb5168ec2bce5548e 688 PRINTS PR00096 Glutamine amidotransferase superfamily signature 82 93 2.6E-12 T 29-03-2018 GBCGDNIH2_RS03915 c03c1f228c0be0cfb5168ec2bce5548e 688 PRINTS PR00096 Glutamine amidotransferase superfamily signature 172 185 2.6E-12 T 29-03-2018 GBCGDNIH2_RS01965 842da410955007eaa4c6bce41731d1db 168 Pfam PF01613 Flavin reductase like domain 11 163 7.0E-35 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 GBCGDNIH2_RS01965 842da410955007eaa4c6bce41731d1db 168 SUPERFAMILY SSF50475 6 164 2.75E-47 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 GBCGDNIH2_RS01965 842da410955007eaa4c6bce41731d1db 168 Gene3D G3DSA:2.30.110.10 1 164 3.8E-42 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 GBCGDNIH2_RS01965 842da410955007eaa4c6bce41731d1db 168 SMART SM00903 11 163 3.6E-56 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 GBCGDNIH2_RS06585 ffc2a8d6357f665c9a7c2219ee656ae8 462 Gene3D G3DSA:1.10.8.60 312 385 3.4E-24 T 29-03-2018 GBCGDNIH2_RS06585 ffc2a8d6357f665c9a7c2219ee656ae8 462 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 225 240 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 GBCGDNIH2_RS06585 ffc2a8d6357f665c9a7c2219ee656ae8 462 SUPERFAMILY SSF52540 141 373 1.47E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS06585 ffc2a8d6357f665c9a7c2219ee656ae8 462 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 352 361 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site GBCGDNIH2_RS06585 ffc2a8d6357f665c9a7c2219ee656ae8 462 Pfam PF00158 Sigma-54 interaction domain 142 305 5.7E-52 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 GBCGDNIH2_RS06585 ffc2a8d6357f665c9a7c2219ee656ae8 462 SMART SM00382 162 302 5.6E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS06585 ffc2a8d6357f665c9a7c2219ee656ae8 462 SMART SM00448 3 116 4.3E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GBCGDNIH2_RS06585 ffc2a8d6357f665c9a7c2219ee656ae8 462 SUPERFAMILY SSF52172 5 186 2.85E-38 T 29-03-2018 IPR011006 CheY-like superfamily GBCGDNIH2_RS06585 ffc2a8d6357f665c9a7c2219ee656ae8 462 SUPERFAMILY SSF46689 352 454 4.93E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 GBCGDNIH2_RS06585 ffc2a8d6357f665c9a7c2219ee656ae8 462 Pfam PF02954 Bacterial regulatory protein, Fis family 413 452 2.1E-9 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 GBCGDNIH2_RS06585 ffc2a8d6357f665c9a7c2219ee656ae8 462 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 418 435 7.4E-5 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 GBCGDNIH2_RS06585 ffc2a8d6357f665c9a7c2219ee656ae8 462 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 435 455 7.4E-5 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 GBCGDNIH2_RS06585 ffc2a8d6357f665c9a7c2219ee656ae8 462 Gene3D G3DSA:1.10.10.60 386 458 4.8E-13 T 29-03-2018 GBCGDNIH2_RS06585 ffc2a8d6357f665c9a7c2219ee656ae8 462 Gene3D G3DSA:3.40.50.2300 3 138 7.3E-32 T 29-03-2018 GBCGDNIH2_RS06585 ffc2a8d6357f665c9a7c2219ee656ae8 462 Pfam PF00072 Response regulator receiver domain 5 116 1.3E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GBCGDNIH2_RS06585 ffc2a8d6357f665c9a7c2219ee656ae8 462 Gene3D G3DSA:3.40.50.300 139 311 2.7E-26 T 29-03-2018 GBCGDNIH2_RS04410 d4ddcbb7ed09a09fe8df652368f7b2d3 158 SUPERFAMILY SSF110087 6 144 1.24E-40 T 29-03-2018 IPR007410 Copper chaperone PCuAC GBCGDNIH2_RS04410 d4ddcbb7ed09a09fe8df652368f7b2d3 158 Pfam PF04314 Copper chaperone PCu(A)C 31 138 3.5E-34 T 29-03-2018 IPR007410 Copper chaperone PCuAC GBCGDNIH2_RS04305 e2d8b01a2b69a7de857fcce9d7f666af 590 Gene3D G3DSA:3.40.50.720 427 549 5.3E-19 T 29-03-2018 GBCGDNIH2_RS04305 e2d8b01a2b69a7de857fcce9d7f666af 590 Pfam PF02254 TrkA-N domain 436 549 9.7E-22 T 29-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 GBCGDNIH2_RS04305 e2d8b01a2b69a7de857fcce9d7f666af 590 Gene3D G3DSA:1.20.91.10 239 320 1.0E-7 T 29-03-2018 GBCGDNIH2_RS04305 e2d8b01a2b69a7de857fcce9d7f666af 590 SUPERFAMILY SSF51735 434 561 3.55E-26 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS04305 e2d8b01a2b69a7de857fcce9d7f666af 590 Pfam PF00999 Sodium/hydrogen exchanger family 11 384 2.4E-72 T 29-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 GBCGDNIH2_RS10345 ddb2334453c937c44ea703e679580579 280 Pfam PF00494 Squalene/phytoene synthase 21 265 1.4E-45 T 29-03-2018 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 GBCGDNIH2_RS10345 ddb2334453c937c44ea703e679580579 280 TIGRFAM TIGR03464 HpnC: squalene synthase HpnC 17 277 7.9E-80 T 29-03-2018 IPR017827 Squalene synthase HpnC GBCGDNIH2_RS10345 ddb2334453c937c44ea703e679580579 280 SUPERFAMILY SSF48576 24 278 5.9E-52 T 29-03-2018 IPR008949 Isoprenoid synthase domain GBCGDNIH2_RS10345 ddb2334453c937c44ea703e679580579 280 Gene3D G3DSA:1.10.600.10 17 279 1.5E-47 T 29-03-2018 IPR008949 Isoprenoid synthase domain GBCGDNIH2_RS00875 2d66bbd6715941c109a16388b7fe5c03 171 Pfam PF04268 Sarcosine oxidase, gamma subunit family 38 167 9.4E-20 T 29-03-2018 IPR007375 Sarcosine oxidase, gamma subunit KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 GBCGDNIH2_RS00875 2d66bbd6715941c109a16388b7fe5c03 171 SUPERFAMILY SSF103025 49 169 3.73E-11 T 29-03-2018 GBCGDNIH2_RS00875 2d66bbd6715941c109a16388b7fe5c03 171 Gene3D G3DSA:3.30.1360.120 43 170 2.2E-6 T 29-03-2018 GBCGDNIH2_RS08595 177a44f619fa0abf3f2085b1775bb1a6 570 Pfam PF00664 ABC transporter transmembrane region 18 282 1.8E-34 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 GBCGDNIH2_RS08595 177a44f619fa0abf3f2085b1775bb1a6 570 Gene3D G3DSA:3.40.50.300 320 569 2.0E-69 T 29-03-2018 GBCGDNIH2_RS08595 177a44f619fa0abf3f2085b1775bb1a6 570 SMART SM00382 357 548 3.8E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS08595 177a44f619fa0abf3f2085b1775bb1a6 570 SUPERFAMILY SSF90123 9 320 4.84E-58 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 GBCGDNIH2_RS08595 177a44f619fa0abf3f2085b1775bb1a6 570 Gene3D G3DSA:1.20.1560.10 1 319 5.2E-51 T 29-03-2018 GBCGDNIH2_RS08595 177a44f619fa0abf3f2085b1775bb1a6 570 SUPERFAMILY SSF52540 321 566 1.23E-83 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS08595 177a44f619fa0abf3f2085b1775bb1a6 570 Pfam PF00005 ABC transporter 348 496 1.0E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GBCGDNIH2_RS08595 177a44f619fa0abf3f2085b1775bb1a6 570 ProSitePatterns PS00211 ABC transporters family signature. 468 482 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GBCGDNIH2_RS00405 7cb2718128ae49978cfc56b5aa966adb 995 Gene3D G3DSA:2.40.30.110 900 995 1.8E-22 T 29-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 GBCGDNIH2_RS00405 7cb2718128ae49978cfc56b5aa966adb 995 Gene3D G3DSA:3.50.50.60 354 561 4.1E-6 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS00405 7cb2718128ae49978cfc56b5aa966adb 995 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 292 301 1.5E-11 T 29-03-2018 GBCGDNIH2_RS00405 7cb2718128ae49978cfc56b5aa966adb 995 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 666 681 1.5E-11 T 29-03-2018 GBCGDNIH2_RS00405 7cb2718128ae49978cfc56b5aa966adb 995 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 178 200 1.5E-11 T 29-03-2018 GBCGDNIH2_RS00405 7cb2718128ae49978cfc56b5aa966adb 995 Gene3D G3DSA:3.30.1360.120 745 853 5.3E-20 T 29-03-2018 GBCGDNIH2_RS00405 7cb2718128ae49978cfc56b5aa966adb 995 Gene3D G3DSA:3.30.1360.120 608 744 3.4E-27 T 29-03-2018 GBCGDNIH2_RS00405 7cb2718128ae49978cfc56b5aa966adb 995 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 883 982 8.2E-20 T 29-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 GBCGDNIH2_RS00405 7cb2718128ae49978cfc56b5aa966adb 995 Gene3D G3DSA:3.50.50.60 171 353 1.2E-17 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS00405 7cb2718128ae49978cfc56b5aa966adb 995 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 22 108 4.6E-26 T 29-03-2018 GBCGDNIH2_RS00405 7cb2718128ae49978cfc56b5aa966adb 995 Pfam PF01571 Aminomethyltransferase folate-binding domain 614 877 3.4E-72 T 29-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal GBCGDNIH2_RS00405 7cb2718128ae49978cfc56b5aa966adb 995 SUPERFAMILY SSF101790 896 992 4.41E-21 T 29-03-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain GBCGDNIH2_RS00405 7cb2718128ae49978cfc56b5aa966adb 995 SUPERFAMILY SSF103025 607 894 5.97E-91 T 29-03-2018 GBCGDNIH2_RS00405 7cb2718128ae49978cfc56b5aa966adb 995 SUPERFAMILY SSF51905 168 482 1.07E-30 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS00405 7cb2718128ae49978cfc56b5aa966adb 995 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 414 430 5.0E-10 T 29-03-2018 GBCGDNIH2_RS00405 7cb2718128ae49978cfc56b5aa966adb 995 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 289 307 5.0E-10 T 29-03-2018 GBCGDNIH2_RS00405 7cb2718128ae49978cfc56b5aa966adb 995 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 179 198 5.0E-10 T 29-03-2018 GBCGDNIH2_RS00405 7cb2718128ae49978cfc56b5aa966adb 995 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 178 444 1.1E-11 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS00405 7cb2718128ae49978cfc56b5aa966adb 995 PIRSF PIRSF037980 7 995 0.0 T 29-03-2018 IPR006277 Sarcosine oxidase, alpha subunit GO:0008115|GO:0046653 KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 GBCGDNIH2_RS00405 7cb2718128ae49978cfc56b5aa966adb 995 TIGRFAM TIGR01372 soxA: sarcosine oxidase, alpha subunit family 12 994 0.0 T 29-03-2018 IPR006277 Sarcosine oxidase, alpha subunit GO:0008115|GO:0046653 KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 GBCGDNIH2_RS00405 7cb2718128ae49978cfc56b5aa966adb 995 Gene3D G3DSA:4.10.1250.10 855 894 1.3E-9 T 29-03-2018 GBCGDNIH2_RS05085 25f61b2d705eccaf80cef546257aa91e 891 Gene3D G3DSA:3.90.740.10 204 240 2.6E-7 T 29-03-2018 GBCGDNIH2_RS05085 25f61b2d705eccaf80cef546257aa91e 891 Gene3D G3DSA:1.10.730.10 532 761 1.9E-62 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 GBCGDNIH2_RS05085 25f61b2d705eccaf80cef546257aa91e 891 SUPERFAMILY SSF46589 827 891 1.88E-12 T 29-03-2018 IPR010978 tRNA-binding arm GO:0000166 GBCGDNIH2_RS05085 25f61b2d705eccaf80cef546257aa91e 891 Hamap MF_02004 Valine--tRNA ligase [valS]. 2 891 15.319 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 GBCGDNIH2_RS05085 25f61b2d705eccaf80cef546257aa91e 891 Gene3D G3DSA:3.40.50.620 1 203 1.3E-56 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GBCGDNIH2_RS05085 25f61b2d705eccaf80cef546257aa91e 891 Gene3D G3DSA:1.10.287.380 820 890 3.3E-21 T 29-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 GBCGDNIH2_RS05085 25f61b2d705eccaf80cef546257aa91e 891 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 43 54 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 GBCGDNIH2_RS05085 25f61b2d705eccaf80cef546257aa91e 891 Gene3D G3DSA:3.40.50.620 312 531 3.1E-70 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GBCGDNIH2_RS05085 25f61b2d705eccaf80cef546257aa91e 891 Pfam PF08264 Anticodon-binding domain of tRNA 621 765 2.3E-34 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 GBCGDNIH2_RS05085 25f61b2d705eccaf80cef546257aa91e 891 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 15 577 1.0E-203 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 GBCGDNIH2_RS05085 25f61b2d705eccaf80cef546257aa91e 891 SUPERFAMILY SSF52374 4 193 4.12E-133 T 29-03-2018 GBCGDNIH2_RS05085 25f61b2d705eccaf80cef546257aa91e 891 SUPERFAMILY SSF52374 356 588 4.12E-133 T 29-03-2018 GBCGDNIH2_RS05085 25f61b2d705eccaf80cef546257aa91e 891 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 827 891 1.9E-12 T 29-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 GBCGDNIH2_RS05085 25f61b2d705eccaf80cef546257aa91e 891 TIGRFAM TIGR00422 valS: valine--tRNA ligase 3 873 0.0 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 GBCGDNIH2_RS05085 25f61b2d705eccaf80cef546257aa91e 891 SUPERFAMILY SSF47323 591 841 1.55E-47 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 GBCGDNIH2_RS05085 25f61b2d705eccaf80cef546257aa91e 891 PRINTS PR00986 Valyl-tRNA synthetase signature 490 508 4.7E-38 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 GBCGDNIH2_RS05085 25f61b2d705eccaf80cef546257aa91e 891 PRINTS PR00986 Valyl-tRNA synthetase signature 459 480 4.7E-38 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 GBCGDNIH2_RS05085 25f61b2d705eccaf80cef546257aa91e 891 PRINTS PR00986 Valyl-tRNA synthetase signature 36 47 4.7E-38 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 GBCGDNIH2_RS05085 25f61b2d705eccaf80cef546257aa91e 891 PRINTS PR00986 Valyl-tRNA synthetase signature 361 374 4.7E-38 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 GBCGDNIH2_RS05085 25f61b2d705eccaf80cef546257aa91e 891 PRINTS PR00986 Valyl-tRNA synthetase signature 231 248 4.7E-38 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 GBCGDNIH2_RS05085 25f61b2d705eccaf80cef546257aa91e 891 SUPERFAMILY SSF50677 192 357 5.1E-58 T 29-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 GBCGDNIH2_RS12030 f68d64a3d0ba8bbb93254c5d1cf17db1 145 PIRSF PIRSF032025 1 145 6.7E-35 T 29-03-2018 IPR008320 Uncharacterised conserved protein UCP032025 GBCGDNIH2_RS12030 f68d64a3d0ba8bbb93254c5d1cf17db1 145 Pfam PF07370 Protein of unknown function (DUF1489) 4 145 1.5E-46 T 29-03-2018 IPR008320 Uncharacterised conserved protein UCP032025 GBCGDNIH2_RS00175 ef960192ff5c8475b0e107c692f575c6 344 PIRSF PIRSF028561 1 319 4.0E-89 T 29-03-2018 IPR014548 Predicted acyltransferase GBCGDNIH2_RS00175 ef960192ff5c8475b0e107c692f575c6 344 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 97 295 4.4E-8 T 29-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 GBCGDNIH2_RS11580 ded13eb31ac99b481c34179e8d2ef3c9 196 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 62 75 - T 29-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 GBCGDNIH2_RS11580 ded13eb31ac99b481c34179e8d2ef3c9 196 Gene3D G3DSA:3.30.230.40 91 196 5.3E-33 T 29-03-2018 GBCGDNIH2_RS11580 ded13eb31ac99b481c34179e8d2ef3c9 196 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 3 196 43.227 T 29-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 GBCGDNIH2_RS11580 ded13eb31ac99b481c34179e8d2ef3c9 196 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 157 169 - T 29-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 GBCGDNIH2_RS11580 ded13eb31ac99b481c34179e8d2ef3c9 196 SUPERFAMILY SSF54211 3 87 7.84E-34 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold GBCGDNIH2_RS11580 ded13eb31ac99b481c34179e8d2ef3c9 196 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 32 175 3.7E-65 T 29-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 GBCGDNIH2_RS11580 ded13eb31ac99b481c34179e8d2ef3c9 196 Gene3D G3DSA:3.30.230.40 3 89 1.0E-35 T 29-03-2018 GBCGDNIH2_RS11580 ded13eb31ac99b481c34179e8d2ef3c9 196 SUPERFAMILY SSF54211 88 180 4.86E-34 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold GBCGDNIH2_RS02640 a4704fb18a3a089f9ff42169bc4a8018 325 Gene3D G3DSA:3.40.50.150 32 297 5.8E-18 T 29-03-2018 GBCGDNIH2_RS02640 a4704fb18a3a089f9ff42169bc4a8018 325 SUPERFAMILY SSF53335 80 289 4.89E-27 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GBCGDNIH2_RS02640 a4704fb18a3a089f9ff42169bc4a8018 325 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 91 290 3.2E-35 T 29-03-2018 GBCGDNIH2_RS07310 ad6d90e154391cfbb1d99e524e3c3064 379 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 10 359 43.241 T 29-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 GBCGDNIH2_RS07310 ad6d90e154391cfbb1d99e524e3c3064 379 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 10 353 1.7E-120 T 29-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 GBCGDNIH2_RS07310 ad6d90e154391cfbb1d99e524e3c3064 379 Gene3D G3DSA:3.30.1490.20 121 183 2.9E-20 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 GBCGDNIH2_RS07310 ad6d90e154391cfbb1d99e524e3c3064 379 Gene3D G3DSA:3.30.470.20 184 357 1.5E-40 T 29-03-2018 GBCGDNIH2_RS07310 ad6d90e154391cfbb1d99e524e3c3064 379 Pfam PF02222 ATP-grasp domain 115 284 7.5E-60 T 29-03-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type GBCGDNIH2_RS07310 ad6d90e154391cfbb1d99e524e3c3064 379 SUPERFAMILY SSF56059 106 303 2.47E-68 T 29-03-2018 GBCGDNIH2_RS07310 ad6d90e154391cfbb1d99e524e3c3064 379 Gene3D G3DSA:3.40.50.20 9 93 2.6E-23 T 29-03-2018 GBCGDNIH2_RS07310 ad6d90e154391cfbb1d99e524e3c3064 379 SUPERFAMILY SSF52440 5 103 8.34E-28 T 29-03-2018 IPR016185 Pre-ATP-grasp domain GBCGDNIH2_RS07310 ad6d90e154391cfbb1d99e524e3c3064 379 SUPERFAMILY SSF51246 308 357 1.02E-12 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 GBCGDNIH2_RS03570 486ef81d85d6b55430b0948a410ad614 352 TIGRFAM TIGR00393 kpsF: sugar isomerase, KpsF/GutQ family 63 308 1.8E-85 T 29-03-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 GBCGDNIH2_RS03570 486ef81d85d6b55430b0948a410ad614 352 Pfam PF00571 CBS domain 283 349 2.5E-7 T 29-03-2018 IPR000644 CBS domain GBCGDNIH2_RS03570 486ef81d85d6b55430b0948a410ad614 352 Pfam PF00571 CBS domain 218 274 1.0E-7 T 29-03-2018 IPR000644 CBS domain GBCGDNIH2_RS03570 486ef81d85d6b55430b0948a410ad614 352 Pfam PF01380 SIS domain 62 190 1.2E-28 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 GBCGDNIH2_RS03570 486ef81d85d6b55430b0948a410ad614 352 PIRSF PIRSF004692 8 352 9.5E-126 T 29-03-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 GBCGDNIH2_RS03570 486ef81d85d6b55430b0948a410ad614 352 Gene3D G3DSA:3.40.50.10490 19 215 9.3E-56 T 29-03-2018 GBCGDNIH2_RS03570 486ef81d85d6b55430b0948a410ad614 352 Gene3D G3DSA:3.10.580.10 278 351 6.6E-11 T 29-03-2018 GBCGDNIH2_RS03570 486ef81d85d6b55430b0948a410ad614 352 Gene3D G3DSA:3.10.580.10 216 277 1.2E-10 T 29-03-2018 GBCGDNIH2_RS03570 486ef81d85d6b55430b0948a410ad614 352 SUPERFAMILY SSF53697 28 301 5.12E-63 T 29-03-2018 GBCGDNIH2_RS03570 486ef81d85d6b55430b0948a410ad614 352 SUPERFAMILY SSF53697 328 352 5.12E-63 T 29-03-2018 GBCGDNIH2_RS03570 486ef81d85d6b55430b0948a410ad614 352 SMART SM00116 227 275 9.3E-5 T 29-03-2018 IPR000644 CBS domain GBCGDNIH2_RS01380 1d4d3dddb7a8a7f45c11893ea0fdf37e 259 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 109 129 1.7E-54 T 29-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 GBCGDNIH2_RS01380 1d4d3dddb7a8a7f45c11893ea0fdf37e 259 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 165 191 1.7E-54 T 29-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 GBCGDNIH2_RS01380 1d4d3dddb7a8a7f45c11893ea0fdf37e 259 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 71 91 1.7E-54 T 29-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 GBCGDNIH2_RS01380 1d4d3dddb7a8a7f45c11893ea0fdf37e 259 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 54 71 1.7E-54 T 29-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 GBCGDNIH2_RS01380 1d4d3dddb7a8a7f45c11893ea0fdf37e 259 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 213 237 1.7E-54 T 29-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 GBCGDNIH2_RS01380 1d4d3dddb7a8a7f45c11893ea0fdf37e 259 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 130 150 1.7E-54 T 29-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 GBCGDNIH2_RS01380 1d4d3dddb7a8a7f45c11893ea0fdf37e 259 TIGRFAM TIGR01191 ccmC: heme exporter protein CcmC 54 236 1.2E-74 T 29-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 GBCGDNIH2_RS01380 1d4d3dddb7a8a7f45c11893ea0fdf37e 259 Pfam PF01578 Cytochrome C assembly protein 35 193 5.1E-29 T 29-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 GBCGDNIH2_RS12025 b0def27d6e1e5b0f7b0f2b42d292877e 213 Gene3D G3DSA:2.40.128.110 46 213 9.9E-47 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like GBCGDNIH2_RS12025 b0def27d6e1e5b0f7b0f2b42d292877e 213 SMART SM00867 47 211 8.5E-60 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like GBCGDNIH2_RS12025 b0def27d6e1e5b0f7b0f2b42d292877e 213 Pfam PF04264 YceI-like domain 48 208 8.3E-38 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like GBCGDNIH2_RS12025 b0def27d6e1e5b0f7b0f2b42d292877e 213 SUPERFAMILY SSF101874 45 212 4.58E-49 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like GBCGDNIH2_RS06155 e4cf58f0c997147383ff4ff81c5e7302 212 SUPERFAMILY SSF51161 92 205 2.36E-31 T 29-03-2018 IPR011004 Trimeric LpxA-like GBCGDNIH2_RS06155 e4cf58f0c997147383ff4ff81c5e7302 212 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 156 190 1.3E-7 T 29-03-2018 IPR001451 Hexapeptide repeat GBCGDNIH2_RS06155 e4cf58f0c997147383ff4ff81c5e7302 212 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 164 192 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 GBCGDNIH2_RS06155 e4cf58f0c997147383ff4ff81c5e7302 212 Gene3D G3DSA:2.160.10.10 54 210 9.7E-33 T 29-03-2018 GBCGDNIH2_RS06715 05858faeea0d0d2da30a4316b6c25d68 296 Gene3D G3DSA:3.40.50.300 66 207 1.2E-9 T 29-03-2018 GBCGDNIH2_RS06715 05858faeea0d0d2da30a4316b6c25d68 296 SUPERFAMILY SSF52540 44 199 1.42E-20 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS06715 05858faeea0d0d2da30a4316b6c25d68 296 Pfam PF05673 Protein of unknown function (DUF815) 34 285 1.0E-101 T 29-03-2018 IPR008533 Domain of unknown function DUF815 GBCGDNIH2_RS01070 ae24423cfece67d41e052bc40ebe2a90 338 Gene3D G3DSA:1.20.58.340 271 338 5.4E-16 T 29-03-2018 GBCGDNIH2_RS01070 ae24423cfece67d41e052bc40ebe2a90 338 Gene3D G3DSA:1.20.58.340 142 270 2.8E-17 T 29-03-2018 GBCGDNIH2_RS01070 ae24423cfece67d41e052bc40ebe2a90 338 SUPERFAMILY SSF143865 37 276 1.7E-33 T 29-03-2018 GBCGDNIH2_RS01070 ae24423cfece67d41e052bc40ebe2a90 338 SUPERFAMILY SSF144083 274 335 5.36E-18 T 29-03-2018 GBCGDNIH2_RS01070 ae24423cfece67d41e052bc40ebe2a90 338 Gene3D G3DSA:3.30.460.20 27 135 4.0E-13 T 29-03-2018 GBCGDNIH2_RS01070 ae24423cfece67d41e052bc40ebe2a90 338 Pfam PF01544 CorA-like Mg2+ transporter protein 37 333 1.6E-53 T 29-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 GBCGDNIH2_RS02650 c61f7af0b39c61abe933b7e5eccc4e41 304 SUPERFAMILY SSF53474 39 295 1.77E-36 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS02650 c61f7af0b39c61abe933b7e5eccc4e41 304 Pfam PF12697 Alpha/beta hydrolase family 57 287 2.2E-13 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 GBCGDNIH2_RS02650 c61f7af0b39c61abe933b7e5eccc4e41 304 Gene3D G3DSA:3.40.50.1820 32 299 7.2E-29 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS01155 eedb68ade06fe28811234e0b423e484f 534 Gene3D G3DSA:3.40.50.2000 355 510 1.4E-14 T 29-03-2018 GBCGDNIH2_RS01155 eedb68ade06fe28811234e0b423e484f 534 SUPERFAMILY SSF53756 182 516 2.87E-28 T 29-03-2018 GBCGDNIH2_RS01155 eedb68ade06fe28811234e0b423e484f 534 Gene3D G3DSA:3.40.50.2000 187 354 1.8E-4 T 29-03-2018 GBCGDNIH2_RS01155 eedb68ade06fe28811234e0b423e484f 534 Pfam PF13692 Glycosyl transferases group 1 356 492 1.3E-19 T 29-03-2018 GBCGDNIH2_RS01135 6440066c6416c28f072c645eb918921c 362 ProSitePatterns PS00787 Chorismate synthase signature 1. 16 31 - T 29-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 GBCGDNIH2_RS01135 6440066c6416c28f072c645eb918921c 362 ProSitePatterns PS00789 Chorismate synthase signature 3. 327 343 - T 29-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 GBCGDNIH2_RS01135 6440066c6416c28f072c645eb918921c 362 Hamap MF_00300 Chorismate synthase [aroC]. 10 360 37.123 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 GBCGDNIH2_RS01135 6440066c6416c28f072c645eb918921c 362 SUPERFAMILY SSF103263 3 359 1.57E-144 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 GBCGDNIH2_RS01135 6440066c6416c28f072c645eb918921c 362 PIRSF PIRSF001456 3 361 5.3E-140 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 GBCGDNIH2_RS01135 6440066c6416c28f072c645eb918921c 362 Pfam PF01264 Chorismate synthase 10 353 8.3E-139 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 GBCGDNIH2_RS01135 6440066c6416c28f072c645eb918921c 362 TIGRFAM TIGR00033 aroC: chorismate synthase 10 358 6.8E-134 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 GBCGDNIH2_RS01135 6440066c6416c28f072c645eb918921c 362 Gene3D G3DSA:3.60.150.10 9 361 3.9E-158 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 GBCGDNIH2_RS06740 908f2208e78525d66dc9ae918849eac0 263 Pfam PF00902 Sec-independent protein translocase protein (TatC) 11 231 5.5E-68 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 GBCGDNIH2_RS06740 908f2208e78525d66dc9ae918849eac0 263 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 2 257 18.226 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 GBCGDNIH2_RS06740 908f2208e78525d66dc9ae918849eac0 263 ProSitePatterns PS01218 TatC family signature. 164 183 - T 29-03-2018 IPR019820 Sec-independent periplasmic protein translocase, conserved site GBCGDNIH2_RS06740 908f2208e78525d66dc9ae918849eac0 263 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 9 236 5.7E-65 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 GBCGDNIH2_RS06740 908f2208e78525d66dc9ae918849eac0 263 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 164 192 8.2E-42 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 GBCGDNIH2_RS06740 908f2208e78525d66dc9ae918849eac0 263 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 89 107 8.2E-42 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 GBCGDNIH2_RS06740 908f2208e78525d66dc9ae918849eac0 263 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 8 35 8.2E-42 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 GBCGDNIH2_RS06740 908f2208e78525d66dc9ae918849eac0 263 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 107 133 8.2E-42 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 GBCGDNIH2_RS02985 d50e06633c6ec9205e8a49aa28c619a4 236 Gene3D G3DSA:3.30.2180.10 1 55 3.7E-14 T 29-03-2018 GBCGDNIH2_RS02985 d50e06633c6ec9205e8a49aa28c619a4 236 Pfam PF07542 ATP12 chaperone protein 2 123 4.3E-27 T 29-03-2018 IPR011419 ATP12, ATP synthase F1-assembly protein GO:0043461 GBCGDNIH2_RS02985 d50e06633c6ec9205e8a49aa28c619a4 236 Gene3D G3DSA:1.10.3580.10 64 233 3.4E-45 T 29-03-2018 IPR023335 Orthogonal Bundle domain in ATP12 GBCGDNIH2_RS02985 d50e06633c6ec9205e8a49aa28c619a4 236 SUPERFAMILY SSF160909 1 229 7.85E-66 T 29-03-2018 GBCGDNIH2_RS02415 c64aa29a4c399bdcb96467436a445c63 492 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 19 471 46.329 T 29-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 GBCGDNIH2_RS02415 c64aa29a4c399bdcb96467436a445c63 492 Pfam PF13537 Glutamine amidotransferase domain 100 223 3.4E-16 T 29-03-2018 IPR017932 Glutamine amidotransferase type 2 domain GBCGDNIH2_RS02415 c64aa29a4c399bdcb96467436a445c63 492 SUPERFAMILY SSF56235 20 262 3.35E-66 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal GBCGDNIH2_RS02415 c64aa29a4c399bdcb96467436a445c63 492 Pfam PF00156 Phosphoribosyl transferase domain 285 395 5.1E-10 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 GBCGDNIH2_RS02415 c64aa29a4c399bdcb96467436a445c63 492 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 20 472 1.0E-153 T 29-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 GBCGDNIH2_RS02415 c64aa29a4c399bdcb96467436a445c63 492 PIRSF PIRSF000485 16 487 7.2E-165 T 29-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 GBCGDNIH2_RS02415 c64aa29a4c399bdcb96467436a445c63 492 Gene3D G3DSA:3.40.50.2020 251 452 5.5E-36 T 29-03-2018 GBCGDNIH2_RS02415 c64aa29a4c399bdcb96467436a445c63 492 Gene3D G3DSA:3.60.20.10 20 250 2.2E-51 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal GBCGDNIH2_RS02415 c64aa29a4c399bdcb96467436a445c63 492 SUPERFAMILY SSF53271 261 478 2.15E-74 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like GBCGDNIH2_RS02895 0222b5e9413f7408702e286ee781c108 187 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 9 187 42.308 T 29-03-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS02895 0222b5e9413f7408702e286ee781c108 187 SUPERFAMILY SSF55282 11 186 2.26E-74 T 29-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02895 0222b5e9413f7408702e286ee781c108 187 ProSitePatterns PS00358 Ribosomal protein L5 signature. 65 81 - T 29-03-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02895 0222b5e9413f7408702e286ee781c108 187 PIRSF PIRSF002161 6 187 3.0E-65 T 29-03-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02895 0222b5e9413f7408702e286ee781c108 187 Pfam PF00281 Ribosomal protein L5 32 88 9.3E-27 T 29-03-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02895 0222b5e9413f7408702e286ee781c108 187 Gene3D G3DSA:3.30.1440.10 9 187 2.7E-76 T 29-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02895 0222b5e9413f7408702e286ee781c108 187 Pfam PF00673 ribosomal L5P family C-terminus 92 185 3.2E-39 T 29-03-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS07890 ca4e4f024a74f7b028f85fe4accfc2e1 445 Gene3D G3DSA:3.40.50.2300 162 340 1.4E-22 T 29-03-2018 GBCGDNIH2_RS07890 ca4e4f024a74f7b028f85fe4accfc2e1 445 Pfam PF13458 Periplasmic binding protein 31 400 1.3E-76 T 29-03-2018 IPR028081 Leucine-binding protein domain GBCGDNIH2_RS07890 ca4e4f024a74f7b028f85fe4accfc2e1 445 SUPERFAMILY SSF53822 41 405 4.37E-50 T 29-03-2018 IPR028082 Periplasmic binding protein-like I GBCGDNIH2_RS07890 ca4e4f024a74f7b028f85fe4accfc2e1 445 Gene3D G3DSA:3.40.50.2300 23 161 3.0E-5 T 29-03-2018 GBCGDNIH2_RS08580 07eb0c38c9c6683f1b5768e0e9888e34 212 SUPERFAMILY SSF101874 43 206 1.26E-49 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like GBCGDNIH2_RS08580 07eb0c38c9c6683f1b5768e0e9888e34 212 Gene3D G3DSA:2.40.128.110 44 212 5.1E-47 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like GBCGDNIH2_RS08580 07eb0c38c9c6683f1b5768e0e9888e34 212 Pfam PF04264 YceI-like domain 46 206 8.8E-39 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like GBCGDNIH2_RS08580 07eb0c38c9c6683f1b5768e0e9888e34 212 SMART SM00867 45 209 1.4E-59 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like GBCGDNIH2_RS05930 78132e81e5a71754ac82b32080618059 278 PIRSF PIRSF004789 1 272 1.7E-88 T 29-03-2018 IPR005235 Metallophosphoesterase, YmdB-like GBCGDNIH2_RS05930 78132e81e5a71754ac82b32080618059 278 SUPERFAMILY SSF56300 1 265 6.83E-80 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like GBCGDNIH2_RS05930 78132e81e5a71754ac82b32080618059 278 Gene3D G3DSA:3.60.21.10 1 272 9.8E-37 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like GBCGDNIH2_RS05930 78132e81e5a71754ac82b32080618059 278 TIGRFAM TIGR00282 TIGR00282: metallophosphoesterase, MG_246/BB_0505 family 1 265 5.0E-77 T 29-03-2018 IPR005235 Metallophosphoesterase, YmdB-like GBCGDNIH2_RS05930 78132e81e5a71754ac82b32080618059 278 Pfam PF13277 YmdB-like protein 5 263 7.4E-97 T 29-03-2018 IPR005235 Metallophosphoesterase, YmdB-like GBCGDNIH2_RS07980 051d92e28a21468e9872b75ce6599979 119 Gene3D G3DSA:1.10.1900.20 55 116 8.3E-28 T 29-03-2018 IPR035566 Ribosomal protein L20 C-terminal domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS07980 051d92e28a21468e9872b75ce6599979 119 SUPERFAMILY SSF74731 3 116 1.01E-46 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS07980 051d92e28a21468e9872b75ce6599979 119 Pfam PF00453 Ribosomal protein L20 3 109 8.9E-47 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS07980 051d92e28a21468e9872b75ce6599979 119 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 28.496 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS07980 051d92e28a21468e9872b75ce6599979 119 PRINTS PR00062 Ribosomal protein L20 signature 42 71 3.3E-35 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS07980 051d92e28a21468e9872b75ce6599979 119 PRINTS PR00062 Ribosomal protein L20 signature 75 101 3.3E-35 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS07980 051d92e28a21468e9872b75ce6599979 119 PRINTS PR00062 Ribosomal protein L20 signature 12 41 3.3E-35 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS07980 051d92e28a21468e9872b75ce6599979 119 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 21 72 8.0E-20 T 29-03-2018 GBCGDNIH2_RS07980 051d92e28a21468e9872b75ce6599979 119 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS07980 051d92e28a21468e9872b75ce6599979 119 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 113 4.0E-48 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS04930 a48ab67cc19d76ec9d180ca398f335c2 329 TIGRFAM TIGR01136 cysKM: cysteine synthase 26 326 3.0E-118 T 29-03-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 GBCGDNIH2_RS04930 a48ab67cc19d76ec9d180ca398f335c2 329 Gene3D G3DSA:3.40.50.1100 160 328 3.7E-54 T 29-03-2018 GBCGDNIH2_RS04930 a48ab67cc19d76ec9d180ca398f335c2 329 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 27 305 3.5E-61 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme GBCGDNIH2_RS04930 a48ab67cc19d76ec9d180ca398f335c2 329 TIGRFAM TIGR01139 cysK: cysteine synthase A 27 326 9.9E-120 T 29-03-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 GBCGDNIH2_RS04930 a48ab67cc19d76ec9d180ca398f335c2 329 Gene3D G3DSA:3.40.50.1100 61 159 5.0E-34 T 29-03-2018 GBCGDNIH2_RS04930 a48ab67cc19d76ec9d180ca398f335c2 329 SUPERFAMILY SSF53686 20 326 3.14E-94 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme GBCGDNIH2_RS06455 3cdd6ad70ceb00534661e3872a8c9ff6 272 SUPERFAMILY SSF53335 4 243 3.58E-46 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GBCGDNIH2_RS06455 3cdd6ad70ceb00534661e3872a8c9ff6 272 Gene3D G3DSA:3.40.50.150 54 260 2.3E-24 T 29-03-2018 GBCGDNIH2_RS06455 3cdd6ad70ceb00534661e3872a8c9ff6 272 Pfam PF05050 Methyltransferase FkbM domain 75 240 7.7E-17 T 29-03-2018 IPR006342 Methyltransferase FkbM GBCGDNIH2_RS06455 3cdd6ad70ceb00534661e3872a8c9ff6 272 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 73 223 1.5E-23 T 29-03-2018 IPR006342 Methyltransferase FkbM GBCGDNIH2_RS09350 c3e5b5b88f0c2c1b8b0c9a44c28f84b0 498 SUPERFAMILY SSF52833 383 494 9.28E-10 T 29-03-2018 IPR012336 Thioredoxin-like fold GBCGDNIH2_RS09350 c3e5b5b88f0c2c1b8b0c9a44c28f84b0 498 Gene3D G3DSA:3.50.50.60 1 387 1.3E-61 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS09350 c3e5b5b88f0c2c1b8b0c9a44c28f84b0 498 Pfam PF01494 FAD binding domain 4 343 1.2E-82 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 GBCGDNIH2_RS09350 c3e5b5b88f0c2c1b8b0c9a44c28f84b0 498 SUPERFAMILY SSF51905 4 178 3.54E-63 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS09350 c3e5b5b88f0c2c1b8b0c9a44c28f84b0 498 SUPERFAMILY SSF51905 277 351 3.54E-63 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS09350 c3e5b5b88f0c2c1b8b0c9a44c28f84b0 498 Gene3D G3DSA:3.40.30.20 433 495 3.0E-5 T 29-03-2018 GBCGDNIH2_RS09350 c3e5b5b88f0c2c1b8b0c9a44c28f84b0 498 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 331 347 6.5E-40 T 29-03-2018 GBCGDNIH2_RS09350 c3e5b5b88f0c2c1b8b0c9a44c28f84b0 498 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 6.5E-40 T 29-03-2018 GBCGDNIH2_RS09350 c3e5b5b88f0c2c1b8b0c9a44c28f84b0 498 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 281 296 6.5E-40 T 29-03-2018 GBCGDNIH2_RS09350 c3e5b5b88f0c2c1b8b0c9a44c28f84b0 498 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 296 312 6.5E-40 T 29-03-2018 GBCGDNIH2_RS09350 c3e5b5b88f0c2c1b8b0c9a44c28f84b0 498 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 157 172 6.5E-40 T 29-03-2018 GBCGDNIH2_RS07630 fac606ab6cbeac0fa3affcd08c2c3827 627 Gene3D G3DSA:3.40.50.1820 263 595 5.8E-18 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS07630 fac606ab6cbeac0fa3affcd08c2c3827 627 Pfam PF07167 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus 134 306 4.9E-72 T 29-03-2018 IPR010941 Poly-beta-hydroxybutyrate polymerase, N-terminal domain GO:0042619 GBCGDNIH2_RS07630 fac606ab6cbeac0fa3affcd08c2c3827 627 TIGRFAM TIGR01838 PHA_synth_I: poly(R)-hydroxyalkanoic acid synthase, class I 82 618 8.5E-213 T 29-03-2018 IPR010963 Poly(R)-hydroxyalkanoic acid synthase, class I GO:0005737|GO:0016746|GO:0042619 GBCGDNIH2_RS07630 fac606ab6cbeac0fa3affcd08c2c3827 627 SUPERFAMILY SSF53474 261 564 1.47E-42 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS07435 51a9901b615b92c06a4b27c76e9e8451 283 Gene3D G3DSA:3.40.190.10 1 60 6.9E-4 T 29-03-2018 GBCGDNIH2_RS07435 51a9901b615b92c06a4b27c76e9e8451 283 Pfam PF10030 Uncharacterized protein conserved in bacteria (DUF2272) 95 279 5.3E-64 T 29-03-2018 IPR019262 Domain of unknown function DUF2272 GBCGDNIH2_RS10425 0793d053b49502134b2fc802374adcc2 242 TIGRFAM TIGR01848 PHA_reg_PhaR: polyhydroxyalkanoate synthesis repressor PhaR 54 159 4.2E-47 T 29-03-2018 IPR010134 Polyhydroxyalkanoate synthesis repressor PhaR GO:0006355 GBCGDNIH2_RS10425 0793d053b49502134b2fc802374adcc2 242 Pfam PF05233 PHB accumulation regulatory domain 119 158 2.7E-17 T 29-03-2018 IPR007897 PHB accumulation regulatory GBCGDNIH2_RS10425 0793d053b49502134b2fc802374adcc2 242 Pfam PF07879 PHB/PHA accumulation regulator DNA-binding domain 55 115 1.0E-30 T 29-03-2018 IPR012909 PHA accumulation regulator DNA-binding, N-terminal GBCGDNIH2_RS02525 8749874b725cd1390f7bb6d894856a68 327 PIRSF PIRSF018005 3 326 1.7E-100 T 29-03-2018 IPR017804 Methyltransferase EgtD-like GBCGDNIH2_RS02525 8749874b725cd1390f7bb6d894856a68 327 Pfam PF10017 Histidine-specific methyltransferase, SAM-dependent 21 325 3.0E-98 T 29-03-2018 IPR019257 Histidine-specific methyltransferase, SAM-dependent GBCGDNIH2_RS02525 8749874b725cd1390f7bb6d894856a68 327 TIGRFAM TIGR03438 egtD_ergothio: dimethylhistidine N-methyltransferase 20 323 8.3E-107 T 29-03-2018 IPR035094 Histidine N-alpha-methyltransferase KEGG: 00340+2.1.1.44|MetaCyc: PWY-7255|MetaCyc: PWY-7550 GBCGDNIH2_RS02525 8749874b725cd1390f7bb6d894856a68 327 Gene3D G3DSA:3.40.50.150 11 325 2.8E-13 T 29-03-2018 GBCGDNIH2_RS09780 2780637016337ce78e63e66a8fd631e4 218 Hamap MF_01398 ATP synthase subunit b [atpF]. 62 199 10.403 T 29-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 GBCGDNIH2_RS09780 2780637016337ce78e63e66a8fd631e4 218 Pfam PF00430 ATP synthase B/B' CF(0) 69 186 1.8E-15 T 29-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 GBCGDNIH2_RS05690 1dc957da76b0f018152b7721dde732ca 426 PRINTS PR01035 Tetracycline resistance protein signature 253 273 3.0E-87 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 GBCGDNIH2_RS05690 1dc957da76b0f018152b7721dde732ca 426 PRINTS PR01035 Tetracycline resistance protein signature 341 364 3.0E-87 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 GBCGDNIH2_RS05690 1dc957da76b0f018152b7721dde732ca 426 PRINTS PR01035 Tetracycline resistance protein signature 81 105 3.0E-87 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 GBCGDNIH2_RS05690 1dc957da76b0f018152b7721dde732ca 426 PRINTS PR01035 Tetracycline resistance protein signature 138 160 3.0E-87 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 GBCGDNIH2_RS05690 1dc957da76b0f018152b7721dde732ca 426 PRINTS PR01035 Tetracycline resistance protein signature 50 69 3.0E-87 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 GBCGDNIH2_RS05690 1dc957da76b0f018152b7721dde732ca 426 PRINTS PR01035 Tetracycline resistance protein signature 371 390 3.0E-87 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 GBCGDNIH2_RS05690 1dc957da76b0f018152b7721dde732ca 426 PRINTS PR01035 Tetracycline resistance protein signature 166 186 3.0E-87 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 GBCGDNIH2_RS05690 1dc957da76b0f018152b7721dde732ca 426 PRINTS PR01035 Tetracycline resistance protein signature 224 241 3.0E-87 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 GBCGDNIH2_RS05690 1dc957da76b0f018152b7721dde732ca 426 PRINTS PR01035 Tetracycline resistance protein signature 21 37 3.0E-87 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 GBCGDNIH2_RS05690 1dc957da76b0f018152b7721dde732ca 426 PRINTS PR01035 Tetracycline resistance protein signature 281 302 3.0E-87 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 GBCGDNIH2_RS05690 1dc957da76b0f018152b7721dde732ca 426 PRINTS PR01035 Tetracycline resistance protein signature 306 326 3.0E-87 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 GBCGDNIH2_RS05690 1dc957da76b0f018152b7721dde732ca 426 PRINTS PR01035 Tetracycline resistance protein signature 108 129 3.0E-87 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 GBCGDNIH2_RS05690 1dc957da76b0f018152b7721dde732ca 426 Pfam PF07690 Major Facilitator Superfamily 18 357 1.1E-44 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 GBCGDNIH2_RS05690 1dc957da76b0f018152b7721dde732ca 426 ProSitePatterns PS00216 Sugar transport proteins signature 1. 68 84 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 GBCGDNIH2_RS05690 1dc957da76b0f018152b7721dde732ca 426 SUPERFAMILY SSF103473 9 397 4.32E-61 T 29-03-2018 IPR020846 Major facilitator superfamily domain GBCGDNIH2_RS05690 1dc957da76b0f018152b7721dde732ca 426 Gene3D G3DSA:1.20.1250.20 4 196 1.8E-37 T 29-03-2018 GBCGDNIH2_RS05690 1dc957da76b0f018152b7721dde732ca 426 Gene3D G3DSA:1.20.1250.20 203 407 2.0E-18 T 29-03-2018 GBCGDNIH2_RS01025 e8711466b616e58f373388acfb3dc030 314 Gene3D G3DSA:2.130.10.10 19 112 1.8E-19 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 GBCGDNIH2_RS01025 e8711466b616e58f373388acfb3dc030 314 Gene3D G3DSA:2.130.10.10 229 311 1.0E-13 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 GBCGDNIH2_RS01025 e8711466b616e58f373388acfb3dc030 314 Gene3D G3DSA:2.130.10.10 113 228 9.2E-30 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 GBCGDNIH2_RS01025 e8711466b616e58f373388acfb3dc030 314 SUPERFAMILY SSF51004 24 307 8.89E-69 T 29-03-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain GBCGDNIH2_RS01025 e8711466b616e58f373388acfb3dc030 314 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 64 104 3.9E-8 T 29-03-2018 IPR011964 YVTN beta-propeller repeat GBCGDNIH2_RS01025 e8711466b616e58f373388acfb3dc030 314 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 147 188 2.1E-7 T 29-03-2018 IPR011964 YVTN beta-propeller repeat GBCGDNIH2_RS01025 e8711466b616e58f373388acfb3dc030 314 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 272 307 3.0E-7 T 29-03-2018 IPR011964 YVTN beta-propeller repeat GBCGDNIH2_RS01025 e8711466b616e58f373388acfb3dc030 314 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 190 229 1.1E-7 T 29-03-2018 IPR011964 YVTN beta-propeller repeat GBCGDNIH2_RS01025 e8711466b616e58f373388acfb3dc030 314 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 105 146 4.2E-9 T 29-03-2018 IPR011964 YVTN beta-propeller repeat GBCGDNIH2_RS01025 e8711466b616e58f373388acfb3dc030 314 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 235 267 3.1E-8 T 29-03-2018 IPR011964 YVTN beta-propeller repeat GBCGDNIH2_RS01025 e8711466b616e58f373388acfb3dc030 314 Pfam PF02239 Cytochrome D1 heme domain 28 135 2.7E-7 T 29-03-2018 GBCGDNIH2_RS03905 dcdac231adf4be7db42d2e5e662b3e8c 287 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 1 277 1.9E-81 T 29-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 GBCGDNIH2_RS03905 dcdac231adf4be7db42d2e5e662b3e8c 287 Gene3D G3DSA:3.30.1300.10 175 282 9.1E-26 T 29-03-2018 GBCGDNIH2_RS03905 dcdac231adf4be7db42d2e5e662b3e8c 287 Gene3D G3DSA:3.40.50.620 1 174 5.0E-67 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GBCGDNIH2_RS03905 dcdac231adf4be7db42d2e5e662b3e8c 287 Pfam PF02569 Pantoate-beta-alanine ligase 4 277 2.4E-89 T 29-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 GBCGDNIH2_RS03905 dcdac231adf4be7db42d2e5e662b3e8c 287 Hamap MF_00158 Pantothenate synthetase [panC]. 2 279 36.566 T 29-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 GBCGDNIH2_RS03905 dcdac231adf4be7db42d2e5e662b3e8c 287 SUPERFAMILY SSF52374 1 277 1.06E-94 T 29-03-2018 GBCGDNIH2_RS01955 5a775f12c4efc47f706bd970ae6645aa 456 SUPERFAMILY SSF56235 35 453 2.7E-50 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal GBCGDNIH2_RS01955 5a775f12c4efc47f706bd970ae6645aa 456 Pfam PF01019 Gamma-glutamyltranspeptidase 322 360 2.5E-6 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 GBCGDNIH2_RS01955 5a775f12c4efc47f706bd970ae6645aa 456 Pfam PF01019 Gamma-glutamyltranspeptidase 54 280 2.9E-28 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 GBCGDNIH2_RS01955 5a775f12c4efc47f706bd970ae6645aa 456 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 347 365 5.1E-18 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 GBCGDNIH2_RS01955 5a775f12c4efc47f706bd970ae6645aa 456 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 122 140 5.1E-18 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 GBCGDNIH2_RS01955 5a775f12c4efc47f706bd970ae6645aa 456 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 61 86 5.1E-18 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 GBCGDNIH2_RS01955 5a775f12c4efc47f706bd970ae6645aa 456 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 323 341 5.1E-18 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 GBCGDNIH2_RS01955 5a775f12c4efc47f706bd970ae6645aa 456 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 140 159 5.1E-18 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 GBCGDNIH2_RS00830 74a522fa76024b5d814a73228ae7a7ed 382 Gene3D G3DSA:3.90.1150.10 253 382 3.7E-37 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 GBCGDNIH2_RS00830 74a522fa76024b5d814a73228ae7a7ed 382 PIRSF PIRSF000390 3 382 6.8E-95 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase GBCGDNIH2_RS00830 74a522fa76024b5d814a73228ae7a7ed 382 Gene3D G3DSA:3.40.640.10 11 252 6.8E-40 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GBCGDNIH2_RS00830 74a522fa76024b5d814a73228ae7a7ed 382 SUPERFAMILY SSF53383 19 379 4.26E-93 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase GBCGDNIH2_RS00830 74a522fa76024b5d814a73228ae7a7ed 382 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 20 377 3.0E-103 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase GBCGDNIH2_RS04905 fe2d21aec368e19a7a6b3f0b1aeda922 124 SUPERFAMILY SSF47413 63 119 2.08E-9 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GBCGDNIH2_RS04905 fe2d21aec368e19a7a6b3f0b1aeda922 124 SMART SM00530 63 117 2.2E-4 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 GBCGDNIH2_RS04905 fe2d21aec368e19a7a6b3f0b1aeda922 124 Pfam PF01381 Helix-turn-helix 64 106 1.6E-5 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 GBCGDNIH2_RS04905 fe2d21aec368e19a7a6b3f0b1aeda922 124 Gene3D G3DSA:1.10.260.40 7 122 3.1E-8 T 29-03-2018 GBCGDNIH2_RS04545 cbb571e5d70a3ee2b901e8fee3cfc12c 631 PRINTS PR01183 Ribonucleotide reductase large chain signature 187 206 2.7E-14 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 GBCGDNIH2_RS04545 cbb571e5d70a3ee2b901e8fee3cfc12c 631 PRINTS PR01183 Ribonucleotide reductase large chain signature 378 400 2.7E-14 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 GBCGDNIH2_RS04545 cbb571e5d70a3ee2b901e8fee3cfc12c 631 PRINTS PR01183 Ribonucleotide reductase large chain signature 441 468 2.7E-14 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 GBCGDNIH2_RS04545 cbb571e5d70a3ee2b901e8fee3cfc12c 631 Pfam PF02867 Ribonucleotide reductase, barrel domain 114 433 3.3E-72 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 GBCGDNIH2_RS04545 cbb571e5d70a3ee2b901e8fee3cfc12c 631 Pfam PF02867 Ribonucleotide reductase, barrel domain 443 588 7.5E-37 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 GBCGDNIH2_RS04545 cbb571e5d70a3ee2b901e8fee3cfc12c 631 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 46 110 3.1E-13 T 29-03-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 GBCGDNIH2_RS04545 cbb571e5d70a3ee2b901e8fee3cfc12c 631 SUPERFAMILY SSF48168 39 109 6.41E-15 T 29-03-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 GBCGDNIH2_RS04545 cbb571e5d70a3ee2b901e8fee3cfc12c 631 SUPERFAMILY SSF51998 522 591 5.8E-136 T 29-03-2018 GBCGDNIH2_RS04545 cbb571e5d70a3ee2b901e8fee3cfc12c 631 SUPERFAMILY SSF51998 112 491 5.8E-136 T 29-03-2018 GBCGDNIH2_RS04545 cbb571e5d70a3ee2b901e8fee3cfc12c 631 Gene3D G3DSA:3.20.70.20 24 596 1.2E-156 T 29-03-2018 GBCGDNIH2_RS05635 1393ed5ff0266d0d654cb04a57f4492f 488 Gene3D G3DSA:2.30.40.10 421 486 6.8E-4 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 GBCGDNIH2_RS05635 1393ed5ff0266d0d654cb04a57f4492f 488 Gene3D G3DSA:3.20.20.140 138 420 3.7E-37 T 29-03-2018 GBCGDNIH2_RS05635 1393ed5ff0266d0d654cb04a57f4492f 488 SUPERFAMILY SSF51556 125 429 2.65E-71 T 29-03-2018 IPR032466 Metal-dependent hydrolase GBCGDNIH2_RS05635 1393ed5ff0266d0d654cb04a57f4492f 488 Gene3D G3DSA:2.30.40.10 68 137 4.3E-13 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 GBCGDNIH2_RS05635 1393ed5ff0266d0d654cb04a57f4492f 488 SUPERFAMILY SSF51338 443 486 1.37E-14 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 GBCGDNIH2_RS05635 1393ed5ff0266d0d654cb04a57f4492f 488 SUPERFAMILY SSF51338 441 465 1.02E-11 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 GBCGDNIH2_RS05635 1393ed5ff0266d0d654cb04a57f4492f 488 SUPERFAMILY SSF51338 60 125 1.02E-11 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 GBCGDNIH2_RS05635 1393ed5ff0266d0d654cb04a57f4492f 488 Pfam PF01979 Amidohydrolase family 121 479 1.3E-22 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 GBCGDNIH2_RS12535 b092503a548cf20cfd8b987b6b22fdcc 183 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 1 160 34.354 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 GBCGDNIH2_RS12535 b092503a548cf20cfd8b987b6b22fdcc 183 Pfam PF01625 Peptide methionine sulfoxide reductase 3 156 5.0E-58 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 GBCGDNIH2_RS12535 b092503a548cf20cfd8b987b6b22fdcc 183 SUPERFAMILY SSF55068 1 166 4.84E-65 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 GBCGDNIH2_RS12535 b092503a548cf20cfd8b987b6b22fdcc 183 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 2 152 8.2E-51 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 GBCGDNIH2_RS12535 b092503a548cf20cfd8b987b6b22fdcc 183 Gene3D G3DSA:3.30.1060.10 1 172 6.5E-64 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 GBCGDNIH2_RS10565 7131c5e8652215e9b4a306324da77b2c 195 SUPERFAMILY SSF55961 46 194 6.77E-24 T 29-03-2018 GBCGDNIH2_RS10565 7131c5e8652215e9b4a306324da77b2c 195 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 48 194 3.0E-30 T 29-03-2018 IPR019587 Polyketide cyclase/dehydrase GBCGDNIH2_RS10565 7131c5e8652215e9b4a306324da77b2c 195 Gene3D G3DSA:3.30.530.20 9 195 1.3E-27 T 29-03-2018 IPR023393 START-like domain GBCGDNIH2_RS04030 3596d5ccbe319f5d773a382abc3d1b56 782 PIRSF PIRSF000382 20 780 0.0 T 29-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 GBCGDNIH2_RS04030 3596d5ccbe319f5d773a382abc3d1b56 782 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 26 775 0.0 T 29-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 GBCGDNIH2_RS04030 3596d5ccbe319f5d773a382abc3d1b56 782 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 449 771 1.2E-153 T 29-03-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 GBCGDNIH2_RS04030 3596d5ccbe319f5d773a382abc3d1b56 782 SUPERFAMILY SSF51726 414 774 5.23E-121 T 29-03-2018 GBCGDNIH2_RS04030 3596d5ccbe319f5d773a382abc3d1b56 782 Gene3D G3DSA:3.20.20.210 408 777 4.3E-130 T 29-03-2018 GBCGDNIH2_RS04030 3596d5ccbe319f5d773a382abc3d1b56 782 SUPERFAMILY SSF51726 24 411 3.14E-112 T 29-03-2018 GBCGDNIH2_RS04030 3596d5ccbe319f5d773a382abc3d1b56 782 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 24 331 2.4E-124 T 29-03-2018 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 GBCGDNIH2_RS04030 3596d5ccbe319f5d773a382abc3d1b56 782 Gene3D G3DSA:3.20.20.210 22 407 2.3E-143 T 29-03-2018 GBCGDNIH2_RS04030 3596d5ccbe319f5d773a382abc3d1b56 782 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 21 776 36.581 T 29-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 GBCGDNIH2_RS11905 2b910a9d1e518a7b9c15190ac1b01223 240 SUPERFAMILY SSF161098 44 229 4.58E-28 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GBCGDNIH2_RS11905 2b910a9d1e518a7b9c15190ac1b01223 240 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 68 236 7.2E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GBCGDNIH2_RS11905 2b910a9d1e518a7b9c15190ac1b01223 240 Gene3D G3DSA:1.10.3720.10 2 239 3.0E-25 T 29-03-2018 GBCGDNIH2_RS10955 c214c9a40dbd736f6fe39bb971a93bb0 300 SUPERFAMILY SSF53850 99 252 8.14E-24 T 29-03-2018 GBCGDNIH2_RS10955 c214c9a40dbd736f6fe39bb971a93bb0 300 Pfam PF03466 LysR substrate binding domain 99 248 3.5E-23 T 29-03-2018 IPR005119 LysR, substrate-binding GBCGDNIH2_RS10955 c214c9a40dbd736f6fe39bb971a93bb0 300 Gene3D G3DSA:3.40.190.10 187 264 1.9E-7 T 29-03-2018 GBCGDNIH2_RS10955 c214c9a40dbd736f6fe39bb971a93bb0 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 52 2.8E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS10955 c214c9a40dbd736f6fe39bb971a93bb0 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 52 63 2.8E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS10955 c214c9a40dbd736f6fe39bb971a93bb0 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 42 2.8E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS10955 c214c9a40dbd736f6fe39bb971a93bb0 300 Gene3D G3DSA:1.10.10.10 9 96 3.1E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS10955 c214c9a40dbd736f6fe39bb971a93bb0 300 Gene3D G3DSA:3.40.190.10 102 186 3.3E-16 T 29-03-2018 GBCGDNIH2_RS10955 c214c9a40dbd736f6fe39bb971a93bb0 300 SUPERFAMILY SSF46785 14 121 2.26E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS10955 c214c9a40dbd736f6fe39bb971a93bb0 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 16 74 3.0E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS09055 5d0d97f84b3c8df791e4f75f123d48c3 115 SUPERFAMILY SSF50022 5 104 4.84E-32 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 GBCGDNIH2_RS09055 5d0d97f84b3c8df791e4f75f123d48c3 115 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 5 102 1.3E-26 T 29-03-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 GBCGDNIH2_RS09055 5d0d97f84b3c8df791e4f75f123d48c3 115 Pfam PF13806 Rieske-like [2Fe-2S] domain 5 100 7.9E-17 T 29-03-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 GBCGDNIH2_RS09055 5d0d97f84b3c8df791e4f75f123d48c3 115 Gene3D G3DSA:2.102.10.10 3 113 5.8E-23 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 GBCGDNIH2_RS08840 ed36ffa573fe584424452b851aa57060 471 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 1 464 8.6E-239 T 29-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 GBCGDNIH2_RS08840 ed36ffa573fe584424452b851aa57060 471 ProSitePatterns PS00450 Aconitase family signature 1. 339 355 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 GBCGDNIH2_RS08840 ed36ffa573fe584424452b851aa57060 471 ProSitePatterns PS01244 Aconitase family signature 2. 399 412 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 GBCGDNIH2_RS08840 ed36ffa573fe584424452b851aa57060 471 Gene3D G3DSA:3.30.499.10 1 153 1.4E-42 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 GBCGDNIH2_RS08840 ed36ffa573fe584424452b851aa57060 471 Gene3D G3DSA:3.30.499.10 303 471 7.7E-54 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 GBCGDNIH2_RS08840 ed36ffa573fe584424452b851aa57060 471 Pfam PF00330 Aconitase family (aconitate hydratase) 7 457 9.3E-162 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 GBCGDNIH2_RS08840 ed36ffa573fe584424452b851aa57060 471 SUPERFAMILY SSF53732 1 466 9.29E-171 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 GBCGDNIH2_RS08840 ed36ffa573fe584424452b851aa57060 471 PRINTS PR00415 Aconitase family signature 195 208 4.7E-50 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 GBCGDNIH2_RS08840 ed36ffa573fe584424452b851aa57060 471 PRINTS PR00415 Aconitase family signature 82 95 4.7E-50 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 GBCGDNIH2_RS08840 ed36ffa573fe584424452b851aa57060 471 PRINTS PR00415 Aconitase family signature 133 148 4.7E-50 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 GBCGDNIH2_RS08840 ed36ffa573fe584424452b851aa57060 471 PRINTS PR00415 Aconitase family signature 286 300 4.7E-50 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 GBCGDNIH2_RS08840 ed36ffa573fe584424452b851aa57060 471 PRINTS PR00415 Aconitase family signature 399 412 4.7E-50 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 GBCGDNIH2_RS08840 ed36ffa573fe584424452b851aa57060 471 PRINTS PR00415 Aconitase family signature 108 116 4.7E-50 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 GBCGDNIH2_RS08840 ed36ffa573fe584424452b851aa57060 471 PRINTS PR00415 Aconitase family signature 119 132 4.7E-50 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 GBCGDNIH2_RS08840 ed36ffa573fe584424452b851aa57060 471 PRINTS PR00415 Aconitase family signature 209 222 4.7E-50 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 GBCGDNIH2_RS08840 ed36ffa573fe584424452b851aa57060 471 PRINTS PR00415 Aconitase family signature 343 354 4.7E-50 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 GBCGDNIH2_RS08840 ed36ffa573fe584424452b851aa57060 471 Gene3D G3DSA:3.40.1060.10 154 288 2.3E-44 T 29-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 GBCGDNIH2_RS08840 ed36ffa573fe584424452b851aa57060 471 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 1 466 60.552 T 29-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 GBCGDNIH2_RS08170 d3c47e0e55b4cade3ad014160a154ac5 1046 Gene3D G3DSA:3.30.70.1320 776 854 9.4E-6 T 29-03-2018 GBCGDNIH2_RS08170 d3c47e0e55b4cade3ad014160a154ac5 1046 Pfam PF00873 AcrB/AcrD/AcrF family 4 1035 0.0 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS08170 d3c47e0e55b4cade3ad014160a154ac5 1046 Gene3D G3DSA:3.30.70.1430 576 677 1.3E-16 T 29-03-2018 GBCGDNIH2_RS08170 d3c47e0e55b4cade3ad014160a154ac5 1046 PRINTS PR00702 Acriflavin resistance protein family signature 447 470 5.1E-89 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS08170 d3c47e0e55b4cade3ad014160a154ac5 1046 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 5.1E-89 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS08170 d3c47e0e55b4cade3ad014160a154ac5 1046 PRINTS PR00702 Acriflavin resistance protein family signature 366 387 5.1E-89 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS08170 d3c47e0e55b4cade3ad014160a154ac5 1046 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 5.1E-89 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS08170 d3c47e0e55b4cade3ad014160a154ac5 1046 PRINTS PR00702 Acriflavin resistance protein family signature 339 362 5.1E-89 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS08170 d3c47e0e55b4cade3ad014160a154ac5 1046 PRINTS PR00702 Acriflavin resistance protein family signature 472 495 5.1E-89 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS08170 d3c47e0e55b4cade3ad014160a154ac5 1046 PRINTS PR00702 Acriflavin resistance protein family signature 630 644 5.1E-89 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS08170 d3c47e0e55b4cade3ad014160a154ac5 1046 PRINTS PR00702 Acriflavin resistance protein family signature 394 418 5.1E-89 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS08170 d3c47e0e55b4cade3ad014160a154ac5 1046 PRINTS PR00702 Acriflavin resistance protein family signature 561 578 5.1E-89 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS08170 d3c47e0e55b4cade3ad014160a154ac5 1046 SUPERFAMILY SSF82693 138 184 1.05E-23 T 29-03-2018 GBCGDNIH2_RS08170 d3c47e0e55b4cade3ad014160a154ac5 1046 SUPERFAMILY SSF82693 277 333 1.05E-23 T 29-03-2018 GBCGDNIH2_RS08170 d3c47e0e55b4cade3ad014160a154ac5 1046 SUPERFAMILY SSF82693 40 133 1.15E-25 T 29-03-2018 GBCGDNIH2_RS08170 d3c47e0e55b4cade3ad014160a154ac5 1046 Gene3D G3DSA:3.30.70.1430 40 142 3.0E-24 T 29-03-2018 GBCGDNIH2_RS08170 d3c47e0e55b4cade3ad014160a154ac5 1046 SUPERFAMILY SSF82693 574 680 1.23E-24 T 29-03-2018 GBCGDNIH2_RS08170 d3c47e0e55b4cade3ad014160a154ac5 1046 Gene3D G3DSA:1.20.1640.10 290 510 1.6E-50 T 29-03-2018 GBCGDNIH2_RS08170 d3c47e0e55b4cade3ad014160a154ac5 1046 SUPERFAMILY SSF82714 185 275 7.46E-21 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains GBCGDNIH2_RS08170 d3c47e0e55b4cade3ad014160a154ac5 1046 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 5 1038 0.0 T 29-03-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 GBCGDNIH2_RS08170 d3c47e0e55b4cade3ad014160a154ac5 1046 SUPERFAMILY SSF82714 731 815 6.02E-18 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains GBCGDNIH2_RS08170 d3c47e0e55b4cade3ad014160a154ac5 1046 SUPERFAMILY SSF82866 840 1036 1.24E-41 T 29-03-2018 GBCGDNIH2_RS08170 d3c47e0e55b4cade3ad014160a154ac5 1046 Gene3D G3DSA:1.20.1640.10 855 1038 1.1E-37 T 29-03-2018 GBCGDNIH2_RS08170 d3c47e0e55b4cade3ad014160a154ac5 1046 Gene3D G3DSA:3.30.2090.10 183 278 8.7E-18 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains GBCGDNIH2_RS08170 d3c47e0e55b4cade3ad014160a154ac5 1046 Gene3D G3DSA:3.30.70.1440 681 775 2.1E-18 T 29-03-2018 GBCGDNIH2_RS08170 d3c47e0e55b4cade3ad014160a154ac5 1046 SUPERFAMILY SSF82866 306 500 8.24E-50 T 29-03-2018 GBCGDNIH2_RS08170 d3c47e0e55b4cade3ad014160a154ac5 1046 SUPERFAMILY SSF82693 681 730 3.66E-27 T 29-03-2018 GBCGDNIH2_RS08170 d3c47e0e55b4cade3ad014160a154ac5 1046 SUPERFAMILY SSF82693 817 866 3.66E-27 T 29-03-2018 GBCGDNIH2_RS09905 a7ed8132a8265e030b1161854782ab1a 341 Gene3D G3DSA:3.40.190.10 139 338 5.4E-42 T 29-03-2018 GBCGDNIH2_RS09905 a7ed8132a8265e030b1161854782ab1a 341 SUPERFAMILY SSF53850 32 337 2.01E-85 T 29-03-2018 GBCGDNIH2_RS09905 a7ed8132a8265e030b1161854782ab1a 341 Gene3D G3DSA:3.40.190.10 30 138 2.7E-21 T 29-03-2018 GBCGDNIH2_RS09905 a7ed8132a8265e030b1161854782ab1a 341 TIGRFAM TIGR00971 3a0106s03: sulfate ABC transporter, sulfate-binding protein 30 335 1.9E-130 T 29-03-2018 IPR005669 Thiosulphate/Sulfate-binding protein GO:0008272|GO:0015419 GBCGDNIH2_RS09905 a7ed8132a8265e030b1161854782ab1a 341 Pfam PF13531 Bacterial extracellular solute-binding protein 43 290 2.8E-45 T 29-03-2018 GBCGDNIH2_RS00090 e67ada4230ed3c49419fde2ce679b23a 101 Pfam PF00216 Bacterial DNA-binding protein 1 90 5.9E-31 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 GBCGDNIH2_RS00090 e67ada4230ed3c49419fde2ce679b23a 101 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 1.2E-14 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 GBCGDNIH2_RS00090 e67ada4230ed3c49419fde2ce679b23a 101 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 1.2E-14 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 GBCGDNIH2_RS00090 e67ada4230ed3c49419fde2ce679b23a 101 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 1.2E-14 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 GBCGDNIH2_RS00090 e67ada4230ed3c49419fde2ce679b23a 101 SUPERFAMILY SSF47729 1 92 2.06E-29 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 GBCGDNIH2_RS00090 e67ada4230ed3c49419fde2ce679b23a 101 Gene3D G3DSA:4.10.520.10 1 94 1.1E-31 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 GBCGDNIH2_RS00090 e67ada4230ed3c49419fde2ce679b23a 101 SMART SM00411 1 90 4.2E-38 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 GBCGDNIH2_RS00895 8065d8128d29fbf282ca3dca5939877d 343 Pfam PF03466 LysR substrate binding domain 100 288 9.7E-15 T 29-03-2018 IPR005119 LysR, substrate-binding GBCGDNIH2_RS00895 8065d8128d29fbf282ca3dca5939877d 343 SUPERFAMILY SSF46785 4 115 4.09E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS00895 8065d8128d29fbf282ca3dca5939877d 343 Gene3D G3DSA:1.10.10.10 7 97 1.9E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS00895 8065d8128d29fbf282ca3dca5939877d 343 SUPERFAMILY SSF53850 100 302 1.61E-18 T 29-03-2018 GBCGDNIH2_RS00895 8065d8128d29fbf282ca3dca5939877d 343 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 26 37 3.6E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS00895 8065d8128d29fbf282ca3dca5939877d 343 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 37 47 3.6E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS00895 8065d8128d29fbf282ca3dca5939877d 343 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 47 58 3.6E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS00895 8065d8128d29fbf282ca3dca5939877d 343 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 69 4.2E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS00895 8065d8128d29fbf282ca3dca5939877d 343 Gene3D G3DSA:3.40.190.10 184 278 1.0E-8 T 29-03-2018 GBCGDNIH2_RS00895 8065d8128d29fbf282ca3dca5939877d 343 Gene3D G3DSA:3.40.190.10 98 183 4.3E-6 T 29-03-2018 GBCGDNIH2_RS00395 1ffa140b89028a96ab394c6f30331fb3 454 Gene3D G3DSA:1.10.4100.10 258 444 3.1E-28 T 29-03-2018 GBCGDNIH2_RS00395 1ffa140b89028a96ab394c6f30331fb3 454 SUPERFAMILY SSF143548 16 154 5.23E-44 T 29-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 GBCGDNIH2_RS00395 1ffa140b89028a96ab394c6f30331fb3 454 TIGRFAM TIGR00720 sda_mono: L-serine ammonia-lyase 2 450 1.9E-192 T 29-03-2018 IPR004644 Iron-sulphur-dependent L-serine dehydratase single chain form GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 GBCGDNIH2_RS00395 1ffa140b89028a96ab394c6f30331fb3 454 Pfam PF03313 Serine dehydratase alpha chain 183 448 2.1E-95 T 29-03-2018 IPR005130 Serine dehydratase-like, alpha subunit GBCGDNIH2_RS00395 1ffa140b89028a96ab394c6f30331fb3 454 Pfam PF03315 Serine dehydratase beta chain 3 153 2.5E-53 T 29-03-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 GBCGDNIH2_RS00395 1ffa140b89028a96ab394c6f30331fb3 454 Gene3D G3DSA:3.30.1330.90 10 156 6.3E-52 T 29-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 GBCGDNIH2_RS02810 82f119e0ce8fa8d84c6a5ccc957adb0d 1387 Pfam PF04983 RNA polymerase Rpb1, domain 3 490 647 3.7E-23 T 29-03-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GBCGDNIH2_RS02810 82f119e0ce8fa8d84c6a5ccc957adb0d 1387 SMART SM00663 236 515 5.0E-183 T 29-03-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GBCGDNIH2_RS02810 82f119e0ce8fa8d84c6a5ccc957adb0d 1387 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 19 1356 0.0 T 29-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GBCGDNIH2_RS02810 82f119e0ce8fa8d84c6a5ccc957adb0d 1387 Gene3D G3DSA:2.40.40.20 347 489 2.9E-39 T 29-03-2018 GBCGDNIH2_RS02810 82f119e0ce8fa8d84c6a5ccc957adb0d 1387 Pfam PF00623 RNA polymerase Rpb1, domain 2 345 385 2.6E-7 T 29-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GBCGDNIH2_RS02810 82f119e0ce8fa8d84c6a5ccc957adb0d 1387 Pfam PF00623 RNA polymerase Rpb1, domain 2 389 486 7.0E-27 T 29-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GBCGDNIH2_RS02810 82f119e0ce8fa8d84c6a5ccc957adb0d 1387 Pfam PF05000 RNA polymerase Rpb1, domain 4 676 748 9.3E-16 T 29-03-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GBCGDNIH2_RS02810 82f119e0ce8fa8d84c6a5ccc957adb0d 1387 Gene3D G3DSA:2.40.50.100 1016 1118 3.9E-12 T 29-03-2018 GBCGDNIH2_RS02810 82f119e0ce8fa8d84c6a5ccc957adb0d 1387 Gene3D G3DSA:2.40.50.100 900 1015 1.9E-30 T 29-03-2018 GBCGDNIH2_RS02810 82f119e0ce8fa8d84c6a5ccc957adb0d 1387 Pfam PF04997 RNA polymerase Rpb1, domain 1 16 343 1.3E-90 T 29-03-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GBCGDNIH2_RS02810 82f119e0ce8fa8d84c6a5ccc957adb0d 1387 SUPERFAMILY SSF64484 1125 1355 0.0 T 29-03-2018 GBCGDNIH2_RS02810 82f119e0ce8fa8d84c6a5ccc957adb0d 1387 SUPERFAMILY SSF64484 16 938 0.0 T 29-03-2018 GBCGDNIH2_RS02810 82f119e0ce8fa8d84c6a5ccc957adb0d 1387 Gene3D G3DSA:2.40.50.100 1145 1205 9.8E-17 T 29-03-2018 GBCGDNIH2_RS02810 82f119e0ce8fa8d84c6a5ccc957adb0d 1387 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 13 1369 18.845 T 29-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GBCGDNIH2_RS02810 82f119e0ce8fa8d84c6a5ccc957adb0d 1387 Pfam PF04998 RNA polymerase Rpb1, domain 5 760 1308 1.1E-76 T 29-03-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GBCGDNIH2_RS11155 491a4d6b804fccc3da605c84f88f3744 423 Pfam PF07690 Major Facilitator Superfamily 32 238 2.4E-20 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 GBCGDNIH2_RS11155 491a4d6b804fccc3da605c84f88f3744 423 Gene3D G3DSA:1.20.1250.20 18 214 1.2E-21 T 29-03-2018 GBCGDNIH2_RS11155 491a4d6b804fccc3da605c84f88f3744 423 SUPERFAMILY SSF103473 21 411 4.19E-47 T 29-03-2018 IPR020846 Major facilitator superfamily domain GBCGDNIH2_RS11155 491a4d6b804fccc3da605c84f88f3744 423 Gene3D G3DSA:1.20.1250.20 215 419 3.4E-22 T 29-03-2018 GBCGDNIH2_RS11155 491a4d6b804fccc3da605c84f88f3744 423 ProSitePatterns PS00216 Sugar transport proteins signature 1. 283 299 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 GBCGDNIH2_RS07640 556dce9f3e7b1f4f30baffd99153f874 414 Pfam PF00155 Aminotransferase class I and II 32 381 5.3E-60 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 GBCGDNIH2_RS07640 556dce9f3e7b1f4f30baffd99153f874 414 Gene3D G3DSA:3.90.1150.10 255 400 3.8E-36 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 GBCGDNIH2_RS07640 556dce9f3e7b1f4f30baffd99153f874 414 SUPERFAMILY SSF53383 2 390 2.58E-107 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase GBCGDNIH2_RS07640 556dce9f3e7b1f4f30baffd99153f874 414 Gene3D G3DSA:3.90.1150.10 8 254 1.3E-43 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 GBCGDNIH2_RS07640 556dce9f3e7b1f4f30baffd99153f874 414 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 236 249 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 GBCGDNIH2_RS07370 91ddac2a1a2de587773034ef48ce1ed9 832 Gene3D G3DSA:3.40.50.300 223 457 1.0E-14 T 29-03-2018 GBCGDNIH2_RS07370 91ddac2a1a2de587773034ef48ce1ed9 832 Gene3D G3DSA:1.10.3210.10 9 159 7.2E-7 T 29-03-2018 GBCGDNIH2_RS07370 91ddac2a1a2de587773034ef48ce1ed9 832 SUPERFAMILY SSF52540 259 311 1.8E-25 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS07370 91ddac2a1a2de587773034ef48ce1ed9 832 SUPERFAMILY SSF52540 469 606 1.8E-25 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS07370 91ddac2a1a2de587773034ef48ce1ed9 832 SUPERFAMILY SSF52540 343 440 1.8E-25 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS07370 91ddac2a1a2de587773034ef48ce1ed9 832 Gene3D G3DSA:3.40.50.300 483 632 4.7E-9 T 29-03-2018 GBCGDNIH2_RS07370 91ddac2a1a2de587773034ef48ce1ed9 832 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 264 639 6.4E-53 T 29-03-2018 IPR006474 Helicase Cas3, CRISPR-associated, core GBCGDNIH2_RS07370 91ddac2a1a2de587773034ef48ce1ed9 832 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 24 196 4.0E-24 T 29-03-2018 IPR006483 CRISPR-associated Cas3-HD domain GBCGDNIH2_RS07370 91ddac2a1a2de587773034ef48ce1ed9 832 SMART SM00487 240 472 0.0053 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain GBCGDNIH2_RS07370 91ddac2a1a2de587773034ef48ce1ed9 832 SMART SM00490 519 605 4.4E-4 T 29-03-2018 IPR001650 Helicase, C-terminal GBCGDNIH2_RS12585 ea654262bb15e4ce07562d037c5921e0 174 Pfam PF10003 Integral membrane protein (DUF2244) 21 157 4.3E-31 T 29-03-2018 IPR019253 Protein of unknown function DUF2244, transmembrane GBCGDNIH2_RS04895 e783de60e363171c1a1ed055cb2cbce8 181 Pfam PF09374 Predicted Peptidoglycan domain 111 170 2.0E-5 T 29-03-2018 IPR018537 Peptidoglycan binding domain GBCGDNIH2_RS04895 e783de60e363171c1a1ed055cb2cbce8 181 Pfam PF05838 Glycosyl hydrolase 108 14 105 2.5E-22 T 29-03-2018 IPR008565 Protein of unknown function DUF847 GBCGDNIH2_RS04895 e783de60e363171c1a1ed055cb2cbce8 181 Gene3D G3DSA:1.20.141.10 1 180 9.5E-40 T 29-03-2018 GBCGDNIH2_RS04895 e783de60e363171c1a1ed055cb2cbce8 181 SUPERFAMILY SSF53955 7 174 3.09E-38 T 29-03-2018 IPR023346 Lysozyme-like domain GBCGDNIH2_RS03070 c5900079b7fbf569a91d2c05cb5f23f0 409 Pfam PF13840 ACT domain 340 401 1.8E-14 T 29-03-2018 IPR027795 GATS-like ACT domain GBCGDNIH2_RS03070 c5900079b7fbf569a91d2c05cb5f23f0 409 PIRSF PIRSF000726 1 64 9.0E-19 T 29-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 GBCGDNIH2_RS03070 c5900079b7fbf569a91d2c05cb5f23f0 409 PIRSF PIRSF000726 60 409 3.2E-128 T 29-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 GBCGDNIH2_RS03070 c5900079b7fbf569a91d2c05cb5f23f0 409 SUPERFAMILY SSF53633 3 247 1.96E-73 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase GBCGDNIH2_RS03070 c5900079b7fbf569a91d2c05cb5f23f0 409 Gene3D G3DSA:3.40.1160.10 1 239 1.7E-69 T 29-03-2018 GBCGDNIH2_RS03070 c5900079b7fbf569a91d2c05cb5f23f0 409 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 3 405 1.1E-126 T 29-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 GBCGDNIH2_RS03070 c5900079b7fbf569a91d2c05cb5f23f0 409 Pfam PF00696 Amino acid kinase family 3 229 1.6E-46 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase GBCGDNIH2_RS03070 c5900079b7fbf569a91d2c05cb5f23f0 409 Gene3D G3DSA:3.30.70.260 240 334 3.1E-24 T 29-03-2018 GBCGDNIH2_RS03070 c5900079b7fbf569a91d2c05cb5f23f0 409 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 29-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 GBCGDNIH2_RS03070 c5900079b7fbf569a91d2c05cb5f23f0 409 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 63 404 1.9E-115 T 29-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 GBCGDNIH2_RS03070 c5900079b7fbf569a91d2c05cb5f23f0 409 Gene3D G3DSA:3.30.70.260 335 404 1.5E-19 T 29-03-2018 GBCGDNIH2_RS03070 c5900079b7fbf569a91d2c05cb5f23f0 409 SUPERFAMILY SSF55021 252 330 1.33E-18 T 29-03-2018 GBCGDNIH2_RS03070 c5900079b7fbf569a91d2c05cb5f23f0 409 SUPERFAMILY SSF55021 334 407 2.29E-21 T 29-03-2018 GBCGDNIH2_RS03070 c5900079b7fbf569a91d2c05cb5f23f0 409 Pfam PF01842 ACT domain 270 327 3.7E-13 T 29-03-2018 IPR002912 ACT domain GBCGDNIH2_RS08165 f6a167afde165dcaa36aaa6a7ce79fe3 127 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 4 122 18.028 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 GBCGDNIH2_RS08165 f6a167afde165dcaa36aaa6a7ce79fe3 127 TIGRFAM TIGR00494 crcB: protein CrcB 5 120 6.2E-25 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 GBCGDNIH2_RS08165 f6a167afde165dcaa36aaa6a7ce79fe3 127 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 5 116 3.5E-22 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 GBCGDNIH2_RS04595 7df60c01f87e034b455090dc1f5b9a39 434 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 18 428 9.3E-224 T 29-03-2018 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 GBCGDNIH2_RS04595 7df60c01f87e034b455090dc1f5b9a39 434 Pfam PF00285 Citrate synthase, C-terminal domain 51 417 1.2E-134 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 GBCGDNIH2_RS04595 7df60c01f87e034b455090dc1f5b9a39 434 ProSitePatterns PS00480 Citrate synthase signature. 308 320 - T 29-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 GBCGDNIH2_RS04595 7df60c01f87e034b455090dc1f5b9a39 434 SUPERFAMILY SSF48256 13 434 3.01E-167 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 GBCGDNIH2_RS04595 7df60c01f87e034b455090dc1f5b9a39 434 PRINTS PR00143 Citrate synthase signature 301 321 2.6E-57 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 GBCGDNIH2_RS04595 7df60c01f87e034b455090dc1f5b9a39 434 PRINTS PR00143 Citrate synthase signature 224 239 2.6E-57 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 GBCGDNIH2_RS04595 7df60c01f87e034b455090dc1f5b9a39 434 PRINTS PR00143 Citrate synthase signature 365 381 2.6E-57 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 GBCGDNIH2_RS04595 7df60c01f87e034b455090dc1f5b9a39 434 PRINTS PR00143 Citrate synthase signature 170 183 2.6E-57 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 GBCGDNIH2_RS04595 7df60c01f87e034b455090dc1f5b9a39 434 PRINTS PR00143 Citrate synthase signature 385 399 2.6E-57 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 GBCGDNIH2_RS04595 7df60c01f87e034b455090dc1f5b9a39 434 PRINTS PR00143 Citrate synthase signature 246 274 2.6E-57 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 GBCGDNIH2_RS04595 7df60c01f87e034b455090dc1f5b9a39 434 PIRSF PIRSF001369 43 434 1.1E-168 T 29-03-2018 IPR024176 Citrate synthase, bacterial-type GBCGDNIH2_RS04595 7df60c01f87e034b455090dc1f5b9a39 434 Gene3D G3DSA:1.10.580.10 343 410 1.2E-7 T 29-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain GBCGDNIH2_RS04595 7df60c01f87e034b455090dc1f5b9a39 434 Gene3D G3DSA:1.10.580.10 34 304 9.3E-94 T 29-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain GBCGDNIH2_RS04475 4f08643e44db447d0012921386f12620 145 Pfam PF03928 Haem-degrading 2 128 4.8E-36 T 29-03-2018 IPR005624 Haem-degrading GBCGDNIH2_RS04475 4f08643e44db447d0012921386f12620 145 SUPERFAMILY SSF143744 2 131 7.45E-43 T 29-03-2018 GBCGDNIH2_RS00680 1efb7b9c48b2cbd303266b4e146d442c 248 SUPERFAMILY SSF69593 7 212 1.31E-36 T 29-03-2018 GBCGDNIH2_RS00680 1efb7b9c48b2cbd303266b4e146d442c 248 SMART SM00563 72 186 9.5E-25 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 GBCGDNIH2_RS00680 1efb7b9c48b2cbd303266b4e146d442c 248 Gene3D G3DSA:3.40.1130.10 31 245 2.0E-35 T 29-03-2018 GBCGDNIH2_RS00680 1efb7b9c48b2cbd303266b4e146d442c 248 Pfam PF01553 Acyltransferase 57 182 3.4E-21 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 GBCGDNIH2_RS02335 0219973ffd92ca86791810705ef78775 269 SUPERFAMILY SSF53335 86 185 1.06E-16 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GBCGDNIH2_RS02335 0219973ffd92ca86791810705ef78775 269 Pfam PF08241 Methyltransferase domain 80 128 5.4E-7 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 GBCGDNIH2_RS02335 0219973ffd92ca86791810705ef78775 269 Gene3D G3DSA:3.40.50.150 58 184 1.4E-12 T 29-03-2018 GBCGDNIH2_RS11780 17960c3cd49c4875f715a7b75e2f2820 398 PIRSF PIRSF000521 9 147 4.6E-9 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 GBCGDNIH2_RS11780 17960c3cd49c4875f715a7b75e2f2820 398 PIRSF PIRSF000521 163 389 2.5E-39 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 GBCGDNIH2_RS11780 17960c3cd49c4875f715a7b75e2f2820 398 SUPERFAMILY SSF53383 5 384 2.93E-118 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase GBCGDNIH2_RS11780 17960c3cd49c4875f715a7b75e2f2820 398 Gene3D G3DSA:3.40.640.10 164 279 5.7E-38 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GBCGDNIH2_RS11780 17960c3cd49c4875f715a7b75e2f2820 398 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 2 387 43.038 T 29-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 GBCGDNIH2_RS11780 17960c3cd49c4875f715a7b75e2f2820 398 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 5 384 1.1E-134 T 29-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 GBCGDNIH2_RS11780 17960c3cd49c4875f715a7b75e2f2820 398 Pfam PF00202 Aminotransferase class-III 12 384 5.7E-113 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 GBCGDNIH2_RS11780 17960c3cd49c4875f715a7b75e2f2820 398 Gene3D G3DSA:3.90.1150.10 2 163 1.2E-46 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 GBCGDNIH2_RS11780 17960c3cd49c4875f715a7b75e2f2820 398 Gene3D G3DSA:3.90.1150.10 280 397 5.9E-27 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 GBCGDNIH2_RS00080 0a3d5f4ad29424594387222f6ae9edb9 328 Pfam PF00107 Zinc-binding dehydrogenase 152 261 1.1E-24 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 GBCGDNIH2_RS00080 0a3d5f4ad29424594387222f6ae9edb9 328 SUPERFAMILY SSF50129 2 145 1.23E-40 T 29-03-2018 IPR011032 GroES-like GBCGDNIH2_RS00080 0a3d5f4ad29424594387222f6ae9edb9 328 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 88 6.4E-9 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 GBCGDNIH2_RS00080 0a3d5f4ad29424594387222f6ae9edb9 328 Gene3D G3DSA:3.90.180.10 1 134 3.9E-39 T 29-03-2018 GBCGDNIH2_RS00080 0a3d5f4ad29424594387222f6ae9edb9 328 SUPERFAMILY SSF51735 113 276 3.41E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS00080 0a3d5f4ad29424594387222f6ae9edb9 328 SMART SM00829 11 326 1.5E-33 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 GBCGDNIH2_RS00080 0a3d5f4ad29424594387222f6ae9edb9 328 Gene3D G3DSA:3.40.50.720 135 312 2.6E-31 T 29-03-2018 GBCGDNIH2_RS04090 cdec1e99b8a98984697d7f079608deff 444 SUPERFAMILY SSF46626 201 308 9.08E-17 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 GBCGDNIH2_RS04090 cdec1e99b8a98984697d7f079608deff 444 Gene3D G3DSA:1.10.760.10 33 173 8.9E-17 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 GBCGDNIH2_RS04090 cdec1e99b8a98984697d7f079608deff 444 SUPERFAMILY SSF46626 50 180 4.29E-21 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 GBCGDNIH2_RS04090 cdec1e99b8a98984697d7f079608deff 444 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 336 421 5.2E-6 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 GBCGDNIH2_RS04090 cdec1e99b8a98984697d7f079608deff 444 SUPERFAMILY SSF46626 325 431 1.51E-12 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 GBCGDNIH2_RS04090 cdec1e99b8a98984697d7f079608deff 444 Gene3D G3DSA:1.10.760.10 316 444 9.6E-11 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 GBCGDNIH2_RS04090 cdec1e99b8a98984697d7f079608deff 444 Gene3D G3DSA:1.10.760.10 199 315 2.3E-16 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 GBCGDNIH2_RS04090 cdec1e99b8a98984697d7f079608deff 444 PIRSF PIRSF000018 26 444 6.3E-127 T 29-03-2018 IPR014353 Membrane-bound alcohol dehydrogenase, cytochrome c subunit GO:0005506|GO:0016020|GO:0016614|GO:0020037 GBCGDNIH2_RS04090 cdec1e99b8a98984697d7f079608deff 444 Pfam PF00034 Cytochrome c 58 159 2.0E-5 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 GBCGDNIH2_RS06445 902185d2e9b9499593dcaa5c73520265 162 Gene3D G3DSA:2.40.280.10 17 136 1.4E-39 T 29-03-2018 IPR023620 Small protein B GBCGDNIH2_RS06445 902185d2e9b9499593dcaa5c73520265 162 TIGRFAM TIGR00086 smpB: SsrA-binding protein 17 158 6.0E-46 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 GBCGDNIH2_RS06445 902185d2e9b9499593dcaa5c73520265 162 SUPERFAMILY SSF74982 15 141 7.59E-42 T 29-03-2018 IPR023620 Small protein B GBCGDNIH2_RS06445 902185d2e9b9499593dcaa5c73520265 162 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 18 141 9.0E-51 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 GBCGDNIH2_RS06445 902185d2e9b9499593dcaa5c73520265 162 Pfam PF01668 SmpB protein 18 159 3.7E-50 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 GBCGDNIH2_RS06445 902185d2e9b9499593dcaa5c73520265 162 Hamap MF_00023 SsrA-binding protein [smpB]. 1 162 59.433 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 GBCGDNIH2_RS06445 902185d2e9b9499593dcaa5c73520265 162 ProSitePatterns PS01317 SsrA-binding protein. 35 47 - T 29-03-2018 IPR020081 SsrA-binding protein, conserved site GBCGDNIH2_RS00040 7288346f9f5359531576d6322fa0284d 288 SUPERFAMILY SSF110849 33 174 1.94E-30 T 29-03-2018 IPR003115 ParB/Sulfiredoxin GBCGDNIH2_RS00040 7288346f9f5359531576d6322fa0284d 288 Gene3D G3DSA:3.90.1530.10 21 126 1.1E-32 T 29-03-2018 GBCGDNIH2_RS00040 7288346f9f5359531576d6322fa0284d 288 Pfam PF02195 ParB-like nuclease domain 35 125 1.6E-24 T 29-03-2018 IPR003115 ParB/Sulfiredoxin GBCGDNIH2_RS00040 7288346f9f5359531576d6322fa0284d 288 SMART SM00470 34 126 7.7E-32 T 29-03-2018 IPR003115 ParB/Sulfiredoxin GBCGDNIH2_RS00040 7288346f9f5359531576d6322fa0284d 288 Gene3D G3DSA:1.10.10.730 127 174 3.2E-21 T 29-03-2018 GBCGDNIH2_RS00040 7288346f9f5359531576d6322fa0284d 288 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 34 199 3.8E-55 T 29-03-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 GBCGDNIH2_RS12630 ede04e9aa2dfcf442970bd26ff729078 157 SUPERFAMILY SSF69047 1 65 1.03E-9 T 29-03-2018 IPR008462 CsbD-like domain GBCGDNIH2_RS12630 ede04e9aa2dfcf442970bd26ff729078 157 Gene3D G3DSA:1.10.1470.10 1 69 2.6E-13 T 29-03-2018 IPR008462 CsbD-like domain GBCGDNIH2_RS12630 ede04e9aa2dfcf442970bd26ff729078 157 Pfam PF05532 CsbD-like 6 56 6.8E-15 T 29-03-2018 IPR008462 CsbD-like domain GBCGDNIH2_RS11190 097e23e87521c97d895d5df529c13f59 469 Gene3D G3DSA:1.25.40.10 104 134 2.7E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS11190 097e23e87521c97d895d5df529c13f59 469 SMART SM00028 51 84 15.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 GBCGDNIH2_RS11190 097e23e87521c97d895d5df529c13f59 469 SMART SM00028 85 118 14.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 GBCGDNIH2_RS11190 097e23e87521c97d895d5df529c13f59 469 SMART SM00028 119 152 5.9 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 GBCGDNIH2_RS11190 097e23e87521c97d895d5df529c13f59 469 Gene3D G3DSA:3.40.50.2000 296 463 1.5E-29 T 29-03-2018 GBCGDNIH2_RS11190 097e23e87521c97d895d5df529c13f59 469 Gene3D G3DSA:1.25.40.10 135 172 4.0E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS11190 097e23e87521c97d895d5df529c13f59 469 Pfam PF13432 Tetratricopeptide repeat 124 171 9.9E-5 T 29-03-2018 GBCGDNIH2_RS11190 097e23e87521c97d895d5df529c13f59 469 Pfam PF13432 Tetratricopeptide repeat 23 75 2.8E-7 T 29-03-2018 GBCGDNIH2_RS11190 097e23e87521c97d895d5df529c13f59 469 SUPERFAMILY SSF48452 19 182 4.22E-26 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS11190 097e23e87521c97d895d5df529c13f59 469 SUPERFAMILY SSF53756 208 449 9.73E-22 T 29-03-2018 GBCGDNIH2_RS11190 097e23e87521c97d895d5df529c13f59 469 Gene3D G3DSA:1.25.40.10 11 103 2.0E-16 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS06775 b9ae8d9e4c1c57647108ceb73ac82477 591 SMART SM01016 7 93 4.0E-29 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 GBCGDNIH2_RS06775 b9ae8d9e4c1c57647108ceb73ac82477 591 Pfam PF05746 DALR anticodon binding domain 461 590 1.1E-31 T 29-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 GBCGDNIH2_RS06775 b9ae8d9e4c1c57647108ceb73ac82477 591 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 132 141 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 GBCGDNIH2_RS06775 b9ae8d9e4c1c57647108ceb73ac82477 591 SUPERFAMILY SSF47323 455 590 2.16E-33 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 GBCGDNIH2_RS06775 b9ae8d9e4c1c57647108ceb73ac82477 591 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 9 93 8.4E-19 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 GBCGDNIH2_RS06775 b9ae8d9e4c1c57647108ceb73ac82477 591 SUPERFAMILY SSF52374 120 472 1.61E-76 T 29-03-2018 GBCGDNIH2_RS06775 b9ae8d9e4c1c57647108ceb73ac82477 591 Pfam PF00750 tRNA synthetases class I (R) 102 177 5.7E-10 T 29-03-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 GBCGDNIH2_RS06775 b9ae8d9e4c1c57647108ceb73ac82477 591 Gene3D G3DSA:3.40.50.620 106 390 9.3E-49 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GBCGDNIH2_RS06775 b9ae8d9e4c1c57647108ceb73ac82477 591 SMART SM00836 461 590 3.0E-58 T 29-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 GBCGDNIH2_RS06775 b9ae8d9e4c1c57647108ceb73ac82477 591 PRINTS PR01038 Arginyl-tRNA synthetase signature 161 174 5.3E-24 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 GBCGDNIH2_RS06775 b9ae8d9e4c1c57647108ceb73ac82477 591 PRINTS PR01038 Arginyl-tRNA synthetase signature 137 153 5.3E-24 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 GBCGDNIH2_RS06775 b9ae8d9e4c1c57647108ceb73ac82477 591 PRINTS PR01038 Arginyl-tRNA synthetase signature 332 353 5.3E-24 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 GBCGDNIH2_RS06775 b9ae8d9e4c1c57647108ceb73ac82477 591 PRINTS PR01038 Arginyl-tRNA synthetase signature 122 137 5.3E-24 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 GBCGDNIH2_RS06775 b9ae8d9e4c1c57647108ceb73ac82477 591 Hamap MF_00123 Arginine--tRNA ligase [argS]. 7 590 23.16 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 GBCGDNIH2_RS06775 b9ae8d9e4c1c57647108ceb73ac82477 591 Gene3D G3DSA:1.10.730.10 427 591 5.9E-44 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 GBCGDNIH2_RS06775 b9ae8d9e4c1c57647108ceb73ac82477 591 SUPERFAMILY SSF55190 4 113 6.54E-18 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 GBCGDNIH2_RS06775 b9ae8d9e4c1c57647108ceb73ac82477 591 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 15 590 2.6E-97 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 GBCGDNIH2_RS06775 b9ae8d9e4c1c57647108ceb73ac82477 591 Gene3D G3DSA:3.30.1360.70 1 105 5.4E-26 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 GBCGDNIH2_RS00275 8c61908cd0c18834f6962fe44bed320b 323 Gene3D G3DSA:3.20.20.360 4 293 5.1E-68 T 29-03-2018 GBCGDNIH2_RS00275 8c61908cd0c18834f6962fe44bed320b 323 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 15 258 1.4E-42 T 29-03-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 GBCGDNIH2_RS00275 8c61908cd0c18834f6962fe44bed320b 323 PIRSF PIRSF015582 3 323 8.6E-88 T 29-03-2018 IPR011206 Citrate lyase beta subunit-like GBCGDNIH2_RS00275 8c61908cd0c18834f6962fe44bed320b 323 SUPERFAMILY SSF51621 11 269 4.66E-65 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 GBCGDNIH2_RS08760 b15befc6a4126a91102ac649781c4744 577 Gene3D G3DSA:2.40.160.50 184 577 5.1E-41 T 29-03-2018 GBCGDNIH2_RS08760 b15befc6a4126a91102ac649781c4744 577 Gene3D G3DSA:3.10.20.310 85 157 5.6E-15 T 29-03-2018 GBCGDNIH2_RS08760 b15befc6a4126a91102ac649781c4744 577 Pfam PF17287 POTRA domain 159 211 2.8E-15 T 29-03-2018 IPR035251 ShlB, POTRA domain GBCGDNIH2_RS08760 b15befc6a4126a91102ac649781c4744 577 PIRSF PIRSF029745 1 577 7.0E-179 T 29-03-2018 IPR027282 Two partner secretion pathway transporter GO:0015031 GBCGDNIH2_RS08760 b15befc6a4126a91102ac649781c4744 577 Pfam PF03865 Haemolysin secretion/activation protein ShlB/FhaC/HecB 216 541 8.7E-72 T 29-03-2018 IPR005565 Haemolysin activator HlyB, C-terminal GBCGDNIH2_RS08760 b15befc6a4126a91102ac649781c4744 577 Pfam PF08479 POTRA domain, ShlB-type 83 157 2.6E-21 T 29-03-2018 IPR013686 Polypeptide-transport-associated, ShlB-type GBCGDNIH2_RS10180 38dfd55be8db8a9c7acf0e67f69ff553 1106 Pfam PF13116 Protein of unknown function 435 603 1.8E-8 T 29-03-2018 IPR025263 Domain of unknown function DUF3971 GBCGDNIH2_RS10180 38dfd55be8db8a9c7acf0e67f69ff553 1106 Pfam PF13502 AsmA-like C-terminal region 912 1082 4.6E-13 T 29-03-2018 IPR032712 AsmA-like, C-terminal GBCGDNIH2_RS10750 a5ca0e7bd20ee66186c9d1b6dcc884af 248 SUPERFAMILY SSF63892 11 244 7.06E-93 T 29-03-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 GBCGDNIH2_RS10750 a5ca0e7bd20ee66186c9d1b6dcc884af 248 TIGRFAM TIGR00559 pdxJ: pyridoxine 5'-phosphate synthase 12 242 3.0E-84 T 29-03-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 GBCGDNIH2_RS10750 a5ca0e7bd20ee66186c9d1b6dcc884af 248 Hamap MF_00279 Pyridoxine 5'-phosphate synthase [pdxJ]. 1 248 116.47 T 29-03-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 GBCGDNIH2_RS10750 a5ca0e7bd20ee66186c9d1b6dcc884af 248 Gene3D G3DSA:3.20.20.70 11 242 3.1E-97 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS10750 a5ca0e7bd20ee66186c9d1b6dcc884af 248 Pfam PF03740 Pyridoxal phosphate biosynthesis protein PdxJ 12 241 6.5E-97 T 29-03-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 GBCGDNIH2_RS08535 d8c9eda757786be58527e52c91f6dce6 342 PRINTS PR00067 Catalase signature 137 155 7.3E-6 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 GBCGDNIH2_RS08535 d8c9eda757786be58527e52c91f6dce6 342 PRINTS PR00067 Catalase signature 57 79 7.3E-6 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 GBCGDNIH2_RS08535 d8c9eda757786be58527e52c91f6dce6 342 PRINTS PR00067 Catalase signature 317 342 7.3E-6 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 GBCGDNIH2_RS08535 d8c9eda757786be58527e52c91f6dce6 342 Gene3D G3DSA:2.40.180.10 26 342 2.5E-66 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 GBCGDNIH2_RS08535 d8c9eda757786be58527e52c91f6dce6 342 SUPERFAMILY SSF56634 30 342 4.58E-75 T 29-03-2018 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 GBCGDNIH2_RS08535 d8c9eda757786be58527e52c91f6dce6 342 PIRSF PIRSF000296 14 342 2.4E-97 T 29-03-2018 IPR024168 Catalase, SrpA-type, predicted GBCGDNIH2_RS08535 d8c9eda757786be58527e52c91f6dce6 342 Pfam PF00199 Catalase 63 335 8.5E-27 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 GBCGDNIH2_RS08535 d8c9eda757786be58527e52c91f6dce6 342 SMART SM01060 17 342 1.2E-6 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 GBCGDNIH2_RS11865 0ec9bbedfcc7e6ea33858cab094fdd69 444 Gene3D G3DSA:3.20.20.140 75 392 4.7E-81 T 29-03-2018 GBCGDNIH2_RS11865 0ec9bbedfcc7e6ea33858cab094fdd69 444 Gene3D G3DSA:2.30.40.10 7 74 3.2E-18 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 GBCGDNIH2_RS11865 0ec9bbedfcc7e6ea33858cab094fdd69 444 ProSitePatterns PS00483 Dihydroorotase signature 2. 307 318 - T 29-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 GBCGDNIH2_RS11865 0ec9bbedfcc7e6ea33858cab094fdd69 444 SUPERFAMILY SSF51556 60 371 1.47E-82 T 29-03-2018 IPR032466 Metal-dependent hydrolase GBCGDNIH2_RS11865 0ec9bbedfcc7e6ea33858cab094fdd69 444 ProSitePatterns PS00482 Dihydroorotase signature 1. 63 71 - T 29-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 GBCGDNIH2_RS11865 0ec9bbedfcc7e6ea33858cab094fdd69 444 Pfam PF01979 Amidohydrolase family 57 424 6.8E-21 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 GBCGDNIH2_RS11865 0ec9bbedfcc7e6ea33858cab094fdd69 444 SUPERFAMILY SSF51338 8 59 7.03E-31 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 GBCGDNIH2_RS11865 0ec9bbedfcc7e6ea33858cab094fdd69 444 SUPERFAMILY SSF51338 371 438 7.03E-31 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 GBCGDNIH2_RS11315 2ee35a0abdc7c2ca1747ba0515caa4ca 544 Gene3D G3DSA:3.50.7.10 188 373 2.6E-99 T 29-03-2018 IPR027409 GroEL-like apical domain GBCGDNIH2_RS11315 2ee35a0abdc7c2ca1747ba0515caa4ca 544 ProSitePatterns PS00296 Chaperonins cpn60 signature. 405 416 - T 29-03-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 GBCGDNIH2_RS11315 2ee35a0abdc7c2ca1747ba0515caa4ca 544 Pfam PF00118 TCP-1/cpn60 chaperonin family 23 525 4.8E-102 T 29-03-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 GBCGDNIH2_RS11315 2ee35a0abdc7c2ca1747ba0515caa4ca 544 Gene3D G3DSA:1.10.560.10 1 187 4.7E-45 T 29-03-2018 IPR027413 GroEL-like equatorial domain GBCGDNIH2_RS11315 2ee35a0abdc7c2ca1747ba0515caa4ca 544 SUPERFAMILY SSF54849 138 204 1.33E-22 T 29-03-2018 GBCGDNIH2_RS11315 2ee35a0abdc7c2ca1747ba0515caa4ca 544 PRINTS PR00298 60kDa chaperonin signature 398 419 8.2E-75 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 GBCGDNIH2_RS11315 2ee35a0abdc7c2ca1747ba0515caa4ca 544 PRINTS PR00298 60kDa chaperonin signature 27 53 8.2E-75 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 GBCGDNIH2_RS11315 2ee35a0abdc7c2ca1747ba0515caa4ca 544 PRINTS PR00298 60kDa chaperonin signature 83 110 8.2E-75 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 GBCGDNIH2_RS11315 2ee35a0abdc7c2ca1747ba0515caa4ca 544 PRINTS PR00298 60kDa chaperonin signature 268 291 8.2E-75 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 GBCGDNIH2_RS11315 2ee35a0abdc7c2ca1747ba0515caa4ca 544 PRINTS PR00298 60kDa chaperonin signature 350 375 8.2E-75 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 GBCGDNIH2_RS11315 2ee35a0abdc7c2ca1747ba0515caa4ca 544 TIGRFAM TIGR02348 GroEL: chaperonin GroL 3 528 4.5E-261 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 GBCGDNIH2_RS11315 2ee35a0abdc7c2ca1747ba0515caa4ca 544 SUPERFAMILY SSF52029 184 376 4.71E-85 T 29-03-2018 IPR027409 GroEL-like apical domain GBCGDNIH2_RS11315 2ee35a0abdc7c2ca1747ba0515caa4ca 544 Gene3D G3DSA:1.10.560.10 374 517 4.6E-26 T 29-03-2018 IPR027413 GroEL-like equatorial domain GBCGDNIH2_RS11315 2ee35a0abdc7c2ca1747ba0515caa4ca 544 SUPERFAMILY SSF48592 406 522 3.25E-78 T 29-03-2018 GBCGDNIH2_RS11315 2ee35a0abdc7c2ca1747ba0515caa4ca 544 SUPERFAMILY SSF48592 7 134 3.25E-78 T 29-03-2018 GBCGDNIH2_RS11315 2ee35a0abdc7c2ca1747ba0515caa4ca 544 Hamap MF_00600 60 kDa chaperonin [groL]. 2 542 42.186 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 GBCGDNIH2_RS10525 9bef27842a40c5d2aa524b3094ffb1de 240 Hamap MF_01200_B Orotidine 5'-phosphate decarboxylase [pyrF]. 14 238 31.833 T 29-03-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 GBCGDNIH2_RS10525 9bef27842a40c5d2aa524b3094ffb1de 240 Gene3D G3DSA:3.20.20.70 11 238 3.6E-58 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS10525 9bef27842a40c5d2aa524b3094ffb1de 240 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 16 231 4.1E-31 T 29-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 GBCGDNIH2_RS10525 9bef27842a40c5d2aa524b3094ffb1de 240 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 65 78 - T 29-03-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 GBCGDNIH2_RS10525 9bef27842a40c5d2aa524b3094ffb1de 240 SMART SM00934 16 233 1.8E-76 T 29-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 GBCGDNIH2_RS10525 9bef27842a40c5d2aa524b3094ffb1de 240 SUPERFAMILY SSF51366 14 238 1.51E-58 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 GBCGDNIH2_RS10525 9bef27842a40c5d2aa524b3094ffb1de 240 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 17 233 1.2E-45 T 29-03-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 GBCGDNIH2_RS00260 32f10a422786459d5192bbb99606cd5b 389 Pfam PF08442 ATP-grasp domain 3 202 6.4E-78 T 29-03-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 GBCGDNIH2_RS00260 32f10a422786459d5192bbb99606cd5b 389 SUPERFAMILY SSF56059 1 237 5.42E-76 T 29-03-2018 GBCGDNIH2_RS00260 32f10a422786459d5192bbb99606cd5b 389 Pfam PF00549 CoA-ligase 262 382 1.2E-26 T 29-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 GBCGDNIH2_RS00260 32f10a422786459d5192bbb99606cd5b 389 PIRSF PIRSF001554 1 388 2.1E-147 T 29-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 GBCGDNIH2_RS00260 32f10a422786459d5192bbb99606cd5b 389 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 257 282 - T 29-03-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 GBCGDNIH2_RS00260 32f10a422786459d5192bbb99606cd5b 389 Gene3D G3DSA:3.40.50.261 240 385 9.1E-45 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 GBCGDNIH2_RS00260 32f10a422786459d5192bbb99606cd5b 389 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 386 42.802 T 29-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 GBCGDNIH2_RS00260 32f10a422786459d5192bbb99606cd5b 389 Gene3D G3DSA:3.30.470.20 95 239 6.2E-50 T 29-03-2018 GBCGDNIH2_RS00260 32f10a422786459d5192bbb99606cd5b 389 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 386 1.9E-156 T 29-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 GBCGDNIH2_RS00260 32f10a422786459d5192bbb99606cd5b 389 SUPERFAMILY SSF52210 239 385 5.36E-54 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 GBCGDNIH2_RS00260 32f10a422786459d5192bbb99606cd5b 389 Gene3D G3DSA:3.30.1490.20 21 94 3.0E-19 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 GBCGDNIH2_RS11120 b014de30fdbfa7d026f2d26f62849219 93 Gene3D G3DSA:1.20.58.130 35 93 1.0E-4 T 29-03-2018 GBCGDNIH2_RS06180 1667ab88ac37f20a2c2f5819b18afdea 384 SUPERFAMILY SSF53067 152 343 4.32E-36 T 29-03-2018 GBCGDNIH2_RS06180 1667ab88ac37f20a2c2f5819b18afdea 384 Gene3D G3DSA:3.30.420.40 14 146 1.1E-35 T 29-03-2018 GBCGDNIH2_RS06180 1667ab88ac37f20a2c2f5819b18afdea 384 Gene3D G3DSA:3.30.420.150 147 345 1.1E-45 T 29-03-2018 GBCGDNIH2_RS06180 1667ab88ac37f20a2c2f5819b18afdea 384 SUPERFAMILY SSF53067 26 145 6.88E-34 T 29-03-2018 GBCGDNIH2_RS06180 1667ab88ac37f20a2c2f5819b18afdea 384 Pfam PF02541 Ppx/GppA phosphatase family 45 342 5.9E-44 T 29-03-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 GBCGDNIH2_RS00990 2bebc4ed63cbc579bb3ae79e0db0b28a 1046 Gene3D G3DSA:3.40.50.2000 821 1021 5.1E-17 T 29-03-2018 GBCGDNIH2_RS00990 2bebc4ed63cbc579bb3ae79e0db0b28a 1046 SUPERFAMILY SSF53756 664 998 5.4E-31 T 29-03-2018 GBCGDNIH2_RS00990 2bebc4ed63cbc579bb3ae79e0db0b28a 1046 Gene3D G3DSA:3.90.550.10 366 645 1.6E-40 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS00990 2bebc4ed63cbc579bb3ae79e0db0b28a 1046 Pfam PF00535 Glycosyl transferase family 2 384 559 1.3E-17 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 GBCGDNIH2_RS00990 2bebc4ed63cbc579bb3ae79e0db0b28a 1046 Gene3D G3DSA:1.25.40.10 3 353 9.9E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS00990 2bebc4ed63cbc579bb3ae79e0db0b28a 1046 SUPERFAMILY SSF53448 382 609 4.67E-39 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS00990 2bebc4ed63cbc579bb3ae79e0db0b28a 1046 Pfam PF13692 Glycosyl transferases group 1 887 1011 2.6E-11 T 29-03-2018 GBCGDNIH2_RS07245 e340585833f9ef41437b8efd374430c3 144 Pfam PF00571 CBS domain 26 61 4.2E-6 T 29-03-2018 IPR000644 CBS domain GBCGDNIH2_RS07245 e340585833f9ef41437b8efd374430c3 144 Pfam PF00571 CBS domain 73 124 8.4E-13 T 29-03-2018 IPR000644 CBS domain GBCGDNIH2_RS07245 e340585833f9ef41437b8efd374430c3 144 SMART SM00116 13 61 0.0015 T 29-03-2018 IPR000644 CBS domain GBCGDNIH2_RS07245 e340585833f9ef41437b8efd374430c3 144 SMART SM00116 79 126 3.0E-9 T 29-03-2018 IPR000644 CBS domain GBCGDNIH2_RS07245 e340585833f9ef41437b8efd374430c3 144 Gene3D G3DSA:3.10.580.10 10 142 4.5E-28 T 29-03-2018 GBCGDNIH2_RS07245 e340585833f9ef41437b8efd374430c3 144 SUPERFAMILY SSF54631 9 140 7.58E-31 T 29-03-2018 GBCGDNIH2_RS01485 b9850c3727df85f6fb0cd9938ab857f6 361 Gene3D G3DSA:3.40.1780.10 1 136 1.3E-27 T 29-03-2018 GBCGDNIH2_RS01485 b9850c3727df85f6fb0cd9938ab857f6 361 Gene3D G3DSA:3.40.1780.10 191 354 5.8E-56 T 29-03-2018 GBCGDNIH2_RS01485 b9850c3727df85f6fb0cd9938ab857f6 361 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 7 353 4.5E-95 T 29-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 GBCGDNIH2_RS01485 b9850c3727df85f6fb0cd9938ab857f6 361 Pfam PF02547 Queuosine biosynthesis protein 9 353 4.1E-118 T 29-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 GBCGDNIH2_RS01485 b9850c3727df85f6fb0cd9938ab857f6 361 SUPERFAMILY SSF111337 7 353 3.79E-117 T 29-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 GBCGDNIH2_RS01485 b9850c3727df85f6fb0cd9938ab857f6 361 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 6 354 42.051 T 29-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 GBCGDNIH2_RS10190 b19f6c192e2e114293cf050468c3bdce 155 PIRSF PIRSF000239 1 148 5.8E-19 T 29-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 GBCGDNIH2_RS10190 b19f6c192e2e114293cf050468c3bdce 155 SUPERFAMILY SSF52833 4 154 3.1E-48 T 29-03-2018 IPR012336 Thioredoxin-like fold GBCGDNIH2_RS10190 b19f6c192e2e114293cf050468c3bdce 155 Pfam PF00578 AhpC/TSA family 7 133 2.8E-37 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 GBCGDNIH2_RS10190 b19f6c192e2e114293cf050468c3bdce 155 Gene3D G3DSA:3.40.30.10 1 154 2.1E-40 T 29-03-2018 GBCGDNIH2_RS00380 c77406a404c29f98af186f41a5acf62a 362 Pfam PF00175 Oxidoreductase NAD-binding domain 129 235 3.3E-14 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 GBCGDNIH2_RS00380 c77406a404c29f98af186f41a5acf62a 362 SUPERFAMILY SSF54292 244 361 8.91E-27 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 GBCGDNIH2_RS00380 c77406a404c29f98af186f41a5acf62a 362 SUPERFAMILY SSF63380 23 118 1.28E-27 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 GBCGDNIH2_RS00380 c77406a404c29f98af186f41a5acf62a 362 Gene3D G3DSA:3.40.50.80 118 250 3.5E-25 T 29-03-2018 GBCGDNIH2_RS00380 c77406a404c29f98af186f41a5acf62a 362 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 312 320 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 GBCGDNIH2_RS00380 c77406a404c29f98af186f41a5acf62a 362 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 284 354 4.1E-12 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 GBCGDNIH2_RS00380 c77406a404c29f98af186f41a5acf62a 362 Pfam PF00970 Oxidoreductase FAD-binding domain 28 117 5.5E-13 T 29-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 GBCGDNIH2_RS00380 c77406a404c29f98af186f41a5acf62a 362 PRINTS PR00406 Cytochrome B5 reductase signature 68 75 1.3E-8 T 29-03-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 GBCGDNIH2_RS00380 c77406a404c29f98af186f41a5acf62a 362 PRINTS PR00406 Cytochrome B5 reductase signature 165 176 1.3E-8 T 29-03-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 GBCGDNIH2_RS00380 c77406a404c29f98af186f41a5acf62a 362 PRINTS PR00406 Cytochrome B5 reductase signature 105 119 1.3E-8 T 29-03-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 GBCGDNIH2_RS00380 c77406a404c29f98af186f41a5acf62a 362 PRINTS PR00406 Cytochrome B5 reductase signature 221 229 1.3E-8 T 29-03-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 GBCGDNIH2_RS00380 c77406a404c29f98af186f41a5acf62a 362 PRINTS PR00406 Cytochrome B5 reductase signature 128 147 1.3E-8 T 29-03-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 GBCGDNIH2_RS00380 c77406a404c29f98af186f41a5acf62a 362 SUPERFAMILY SSF52343 108 251 8.51E-35 T 29-03-2018 GBCGDNIH2_RS00380 c77406a404c29f98af186f41a5acf62a 362 Gene3D G3DSA:2.40.30.10 21 117 2.3E-22 T 29-03-2018 GBCGDNIH2_RS00380 c77406a404c29f98af186f41a5acf62a 362 Gene3D G3DSA:3.10.20.30 251 362 1.9E-28 T 29-03-2018 IPR012675 Beta-grasp domain GBCGDNIH2_RS10635 cd9707dd1aafff839fbb98d030f4fe94 621 Gene3D G3DSA:3.40.50.300 307 604 1.7E-51 T 29-03-2018 GBCGDNIH2_RS10635 cd9707dd1aafff839fbb98d030f4fe94 621 SMART SM00382 335 502 1.3E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS10635 cd9707dd1aafff839fbb98d030f4fe94 621 SMART SM00382 28 221 3.4E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS10635 cd9707dd1aafff839fbb98d030f4fe94 621 SUPERFAMILY SSF52540 294 514 9.41E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS10635 cd9707dd1aafff839fbb98d030f4fe94 621 ProSitePatterns PS00211 ABC transporters family signature. 429 443 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GBCGDNIH2_RS10635 cd9707dd1aafff839fbb98d030f4fe94 621 SUPERFAMILY SSF52540 4 226 1.08E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS10635 cd9707dd1aafff839fbb98d030f4fe94 621 Pfam PF12848 ABC transporter 215 294 1.6E-22 T 29-03-2018 IPR032781 ABC-transporter extension domain GBCGDNIH2_RS10635 cd9707dd1aafff839fbb98d030f4fe94 621 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GBCGDNIH2_RS10635 cd9707dd1aafff839fbb98d030f4fe94 621 Gene3D G3DSA:3.40.50.300 1 284 7.5E-51 T 29-03-2018 GBCGDNIH2_RS10635 cd9707dd1aafff839fbb98d030f4fe94 621 Pfam PF00005 ABC transporter 326 457 3.3E-19 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GBCGDNIH2_RS10635 cd9707dd1aafff839fbb98d030f4fe94 621 Pfam PF00005 ABC transporter 20 176 1.5E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GBCGDNIH2_RS10740 6ea8a3ece7041b53458eafd7717a9937 300 Gene3D G3DSA:1.10.150.130 3 130 5.4E-19 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal GBCGDNIH2_RS10740 6ea8a3ece7041b53458eafd7717a9937 300 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 5 299 48.92 T 29-03-2018 IPR023009 Tyrosine recombinase XerC/XerD GBCGDNIH2_RS10740 6ea8a3ece7041b53458eafd7717a9937 300 Pfam PF00589 Phage integrase family 132 284 2.4E-35 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 GBCGDNIH2_RS10740 6ea8a3ece7041b53458eafd7717a9937 300 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 10 95 2.6E-13 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 GBCGDNIH2_RS10740 6ea8a3ece7041b53458eafd7717a9937 300 Gene3D G3DSA:1.10.443.10 131 293 1.9E-40 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 GBCGDNIH2_RS10740 6ea8a3ece7041b53458eafd7717a9937 300 SUPERFAMILY SSF47823 9 99 2.55E-9 T 29-03-2018 IPR010998 Integrase, Lambda-type, N-terminal GBCGDNIH2_RS10740 6ea8a3ece7041b53458eafd7717a9937 300 SUPERFAMILY SSF56349 111 297 5.0E-46 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 GBCGDNIH2_RS01545 f2ee3c1cf7f46e8fdbea4c8dc71c1b84 274 Pfam PF02110 Hydroxyethylthiazole kinase family 20 261 3.8E-81 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 GBCGDNIH2_RS01545 f2ee3c1cf7f46e8fdbea4c8dc71c1b84 274 TIGRFAM TIGR00694 thiM: hydroxyethylthiazole kinase 19 261 3.8E-82 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 GBCGDNIH2_RS01545 f2ee3c1cf7f46e8fdbea4c8dc71c1b84 274 Hamap MF_00228 Hydroxyethylthiazole kinase [thiM]. 21 266 31.943 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 GBCGDNIH2_RS01545 f2ee3c1cf7f46e8fdbea4c8dc71c1b84 274 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 40 61 2.4E-40 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 GBCGDNIH2_RS01545 f2ee3c1cf7f46e8fdbea4c8dc71c1b84 274 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 127 141 2.4E-40 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 GBCGDNIH2_RS01545 f2ee3c1cf7f46e8fdbea4c8dc71c1b84 274 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 97 114 2.4E-40 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 GBCGDNIH2_RS01545 f2ee3c1cf7f46e8fdbea4c8dc71c1b84 274 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 171 188 2.4E-40 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 GBCGDNIH2_RS01545 f2ee3c1cf7f46e8fdbea4c8dc71c1b84 274 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 71 79 2.4E-40 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 GBCGDNIH2_RS01545 f2ee3c1cf7f46e8fdbea4c8dc71c1b84 274 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 27 34 2.4E-40 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 GBCGDNIH2_RS01545 f2ee3c1cf7f46e8fdbea4c8dc71c1b84 274 SUPERFAMILY SSF53613 20 270 1.87E-62 T 29-03-2018 IPR029056 Ribokinase-like GBCGDNIH2_RS01545 f2ee3c1cf7f46e8fdbea4c8dc71c1b84 274 Gene3D G3DSA:3.40.1190.20 1 273 9.4E-60 T 29-03-2018 IPR029056 Ribokinase-like GBCGDNIH2_RS01545 f2ee3c1cf7f46e8fdbea4c8dc71c1b84 274 PIRSF PIRSF000513 13 271 5.4E-92 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 GBCGDNIH2_RS07120 1d87adbfe8ce5b54ca668b0406118292 176 Pfam PF02082 Transcriptional regulator 3 86 1.9E-18 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type GBCGDNIH2_RS07120 1d87adbfe8ce5b54ca668b0406118292 176 SUPERFAMILY SSF46785 3 138 4.36E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS07120 1d87adbfe8ce5b54ca668b0406118292 176 Gene3D G3DSA:1.10.10.10 2 141 3.0E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS07120 1d87adbfe8ce5b54ca668b0406118292 176 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 3 136 5.0E-27 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type GBCGDNIH2_RS07120 1d87adbfe8ce5b54ca668b0406118292 176 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 53 71 - T 29-03-2018 IPR030489 Transcription regulator Rrf2-type, conserved site GBCGDNIH2_RS07120 1d87adbfe8ce5b54ca668b0406118292 176 TIGRFAM TIGR02944 suf_reg_Xantho: FeS assembly SUF system regulator 1 135 1.6E-36 T 29-03-2018 IPR014290 SUF system FeS cluster assembly regulator GBCGDNIH2_RS02380 fbcac9f0a390db7b30b2da5da588930d 619 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 11 616 25.79 T 29-03-2018 IPR020667 DNA mismatch repair protein, MutL GO:0006298 GBCGDNIH2_RS02380 fbcac9f0a390db7b30b2da5da588930d 619 Gene3D G3DSA:3.30.565.10 10 202 4.4E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS02380 fbcac9f0a390db7b30b2da5da588930d 619 SUPERFAMILY SSF55874 11 209 1.28E-46 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS02380 fbcac9f0a390db7b30b2da5da588930d 619 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 216 333 2.7E-33 T 29-03-2018 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 GBCGDNIH2_RS02380 fbcac9f0a390db7b30b2da5da588930d 619 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 102 108 - T 29-03-2018 IPR014762 DNA mismatch repair, conserved site GBCGDNIH2_RS02380 fbcac9f0a390db7b30b2da5da588930d 619 SMART SM00853 432 576 2.3E-50 T 29-03-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 GBCGDNIH2_RS02380 fbcac9f0a390db7b30b2da5da588930d 619 SMART SM01340 216 334 8.4E-47 T 29-03-2018 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 GBCGDNIH2_RS02380 fbcac9f0a390db7b30b2da5da588930d 619 SUPERFAMILY SSF118116 427 618 2.88E-53 T 29-03-2018 GBCGDNIH2_RS02380 fbcac9f0a390db7b30b2da5da588930d 619 Gene3D G3DSA:3.30.230.10 203 333 2.4E-24 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup GBCGDNIH2_RS02380 fbcac9f0a390db7b30b2da5da588930d 619 Pfam PF08676 MutL C terminal dimerisation domain 428 576 5.9E-44 T 29-03-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 GBCGDNIH2_RS02380 fbcac9f0a390db7b30b2da5da588930d 619 SUPERFAMILY SSF54211 208 334 1.29E-28 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold GBCGDNIH2_RS02380 fbcac9f0a390db7b30b2da5da588930d 619 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 34 124 2.2E-10 T 29-03-2018 GBCGDNIH2_RS02380 fbcac9f0a390db7b30b2da5da588930d 619 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 12 313 2.2E-83 T 29-03-2018 IPR002099 DNA mismatch repair protein family GO:0005524|GO:0006298|GO:0030983 GBCGDNIH2_RS11840 04319a9c2f6aaa1439839484c6ea73ea 166 SUPERFAMILY SSF89095 16 165 1.05E-31 T 29-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 GBCGDNIH2_RS11840 04319a9c2f6aaa1439839484c6ea73ea 166 Gene3D G3DSA:1.10.10.410 109 165 4.1E-11 T 29-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal GBCGDNIH2_RS11840 04319a9c2f6aaa1439839484c6ea73ea 166 Gene3D G3DSA:1.10.1510.10 16 108 1.0E-23 T 29-03-2018 GBCGDNIH2_RS11840 04319a9c2f6aaa1439839484c6ea73ea 166 Pfam PF09424 Yqey-like protein 20 164 4.4E-38 T 29-03-2018 IPR019004 Uncharacterised domain YOR215C, mitochondrial GBCGDNIH2_RS09930 96824a25171ff9ccb41db666857edbfc 481 SMART SM00304 214 265 3.7E-7 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 GBCGDNIH2_RS09930 96824a25171ff9ccb41db666857edbfc 481 PRINTS PR00344 Bacterial sensor protein C-terminal signature 432 450 3.3E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS09930 96824a25171ff9ccb41db666857edbfc 481 PRINTS PR00344 Bacterial sensor protein C-terminal signature 397 411 3.3E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS09930 96824a25171ff9ccb41db666857edbfc 481 PRINTS PR00344 Bacterial sensor protein C-terminal signature 456 469 3.3E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS09930 96824a25171ff9ccb41db666857edbfc 481 SUPERFAMILY SSF55874 324 473 8.37E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS09930 96824a25171ff9ccb41db666857edbfc 481 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 368 470 5.1E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS09930 96824a25171ff9ccb41db666857edbfc 481 SMART SM00387 363 472 1.8E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS09930 96824a25171ff9ccb41db666857edbfc 481 Gene3D G3DSA:3.30.565.10 326 481 9.0E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS09930 96824a25171ff9ccb41db666857edbfc 481 SUPERFAMILY SSF47384 249 319 5.1E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GBCGDNIH2_RS09930 96824a25171ff9ccb41db666857edbfc 481 SMART SM00388 266 324 2.9E-6 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GBCGDNIH2_RS09930 96824a25171ff9ccb41db666857edbfc 481 Pfam PF00672 HAMP domain 216 262 1.2E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 GBCGDNIH2_RS09930 96824a25171ff9ccb41db666857edbfc 481 Gene3D G3DSA:1.10.287.130 256 319 1.9E-7 T 29-03-2018 GBCGDNIH2_RS08040 6b11fe47a1f5f1d745bf8ae1690953c5 570 Pfam PF01443 Viral (Superfamily 1) RNA helicase 416 522 9.8E-6 T 29-03-2018 IPR027351 (+) RNA virus helicase core domain GO:0005524 GBCGDNIH2_RS08040 6b11fe47a1f5f1d745bf8ae1690953c5 570 Gene3D G3DSA:3.40.50.300 114 544 3.1E-10 T 29-03-2018 GBCGDNIH2_RS08040 6b11fe47a1f5f1d745bf8ae1690953c5 570 SUPERFAMILY SSF55464 2 269 7.32E-84 T 29-03-2018 GBCGDNIH2_RS08040 6b11fe47a1f5f1d745bf8ae1690953c5 570 TIGRFAM TIGR02686 relax_trwC: conjugative relaxase domain 14 261 2.9E-81 T 29-03-2018 IPR014059 Conjugative relaxase, N-terminal GBCGDNIH2_RS08040 6b11fe47a1f5f1d745bf8ae1690953c5 570 SUPERFAMILY SSF52540 408 529 1.22E-18 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS08040 6b11fe47a1f5f1d745bf8ae1690953c5 570 SUPERFAMILY SSF52540 291 323 1.22E-18 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS08040 6b11fe47a1f5f1d745bf8ae1690953c5 570 Pfam PF08751 TrwC relaxase 11 261 4.4E-84 T 29-03-2018 IPR014862 TrwC relaxase GBCGDNIH2_RS03085 a18bdf5cf9002ad54297d37c96f2661a 426 Pfam PF13413 Helix-turn-helix domain 22 81 4.2E-21 T 29-03-2018 GBCGDNIH2_RS03085 a18bdf5cf9002ad54297d37c96f2661a 426 Gene3D G3DSA:1.10.260.40 9 92 2.3E-8 T 29-03-2018 GBCGDNIH2_RS03085 a18bdf5cf9002ad54297d37c96f2661a 426 Pfam PF13464 Domain of unknown function (DUF4115) 293 368 4.8E-18 T 29-03-2018 IPR025194 Domain of unknown function DUF4115 GBCGDNIH2_RS03110 c88de665201c5f4642530af0e26a40fa 288 Pfam PF13847 Methyltransferase domain 116 240 1.8E-10 T 29-03-2018 IPR025714 Methyltransferase domain GBCGDNIH2_RS03110 c88de665201c5f4642530af0e26a40fa 288 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 27 276 3.0E-70 T 29-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 GBCGDNIH2_RS03110 c88de665201c5f4642530af0e26a40fa 288 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 5 280 37.603 T 29-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 GBCGDNIH2_RS03110 c88de665201c5f4642530af0e26a40fa 288 Gene3D G3DSA:3.40.50.150 81 279 8.0E-39 T 29-03-2018 GBCGDNIH2_RS03110 c88de665201c5f4642530af0e26a40fa 288 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 4 274 4.5E-55 T 29-03-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 GBCGDNIH2_RS03110 c88de665201c5f4642530af0e26a40fa 288 SUPERFAMILY SSF53335 63 246 2.94E-45 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GBCGDNIH2_RS03110 c88de665201c5f4642530af0e26a40fa 288 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 184 190 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 GBCGDNIH2_RS03110 c88de665201c5f4642530af0e26a40fa 288 Gene3D G3DSA:1.10.8.10 3 80 2.0E-18 T 29-03-2018 GBCGDNIH2_RS06695 48fc0de67774c97d293eca8a65585454 398 Gene3D G3DSA:1.10.760.10 289 398 2.8E-4 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 GBCGDNIH2_RS06695 48fc0de67774c97d293eca8a65585454 398 Pfam PF06181 Urate oxidase N-terminal 7 300 1.0E-129 T 29-03-2018 IPR010389 Urate oxidase N-terminal GBCGDNIH2_RS05885 e281e15531f03be4b9a32f75c5cb18b2 332 SUPERFAMILY SSF55681 16 330 9.12E-73 T 29-03-2018 GBCGDNIH2_RS05885 e281e15531f03be4b9a32f75c5cb18b2 332 TIGRFAM TIGR00462 genX: EF-P lysine aminoacylase GenX 18 328 8.7E-116 T 29-03-2018 IPR004525 Elongation factor P--(R)-beta-lysine ligase GO:0004824|GO:0005524|GO:0005737|GO:0006430 GBCGDNIH2_RS05885 e281e15531f03be4b9a32f75c5cb18b2 332 PRINTS PR00982 Lysyl-tRNA synthetase signature 33 43 6.6E-12 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 GBCGDNIH2_RS05885 e281e15531f03be4b9a32f75c5cb18b2 332 PRINTS PR00982 Lysyl-tRNA synthetase signature 217 233 6.6E-12 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 GBCGDNIH2_RS05885 e281e15531f03be4b9a32f75c5cb18b2 332 PRINTS PR00982 Lysyl-tRNA synthetase signature 82 95 6.6E-12 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 GBCGDNIH2_RS05885 e281e15531f03be4b9a32f75c5cb18b2 332 PRINTS PR00982 Lysyl-tRNA synthetase signature 100 117 6.6E-12 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 GBCGDNIH2_RS05885 e281e15531f03be4b9a32f75c5cb18b2 332 Gene3D G3DSA:3.30.930.10 13 332 4.6E-59 T 29-03-2018 GBCGDNIH2_RS05885 e281e15531f03be4b9a32f75c5cb18b2 332 Pfam PF00152 tRNA synthetases class II (D, K and N) 18 331 5.7E-40 T 29-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 GBCGDNIH2_RS05190 26a5d43131dcbd7b48193f6fe74fedd4 269 SUPERFAMILY SSF48576 9 221 1.73E-29 T 29-03-2018 IPR008949 Isoprenoid synthase domain GBCGDNIH2_RS05190 26a5d43131dcbd7b48193f6fe74fedd4 269 Gene3D G3DSA:1.10.600.10 3 263 1.0E-29 T 29-03-2018 IPR008949 Isoprenoid synthase domain GBCGDNIH2_RS05190 26a5d43131dcbd7b48193f6fe74fedd4 269 Pfam PF00494 Squalene/phytoene synthase 13 243 5.8E-29 T 29-03-2018 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 GBCGDNIH2_RS05465 0402dd706d9ac3942828231b93635fab 496 PIRSF PIRSF006060 18 493 4.4E-86 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 GBCGDNIH2_RS05465 0402dd706d9ac3942828231b93635fab 496 Pfam PF13520 Amino acid permease 36 476 2.0E-49 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 GBCGDNIH2_RS10770 efede833ae394a0e02822204c4d324f8 963 PIRSF PIRSF000157 2 961 0.0 T 29-03-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 GBCGDNIH2_RS10770 efede833ae394a0e02822204c4d324f8 963 Gene3D G3DSA:3.40.50.970 614 823 3.8E-57 T 29-03-2018 GBCGDNIH2_RS10770 efede833ae394a0e02822204c4d324f8 963 SMART SM00861 615 808 9.4E-60 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain GBCGDNIH2_RS10770 efede833ae394a0e02822204c4d324f8 963 Gene3D G3DSA:3.40.50.970 181 543 8.6E-91 T 29-03-2018 GBCGDNIH2_RS10770 efede833ae394a0e02822204c4d324f8 963 Pfam PF00676 Dehydrogenase E1 component 229 543 1.5E-56 T 29-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 GBCGDNIH2_RS10770 efede833ae394a0e02822204c4d324f8 963 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 9 48 3.8E-12 T 29-03-2018 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 GBCGDNIH2_RS10770 efede833ae394a0e02822204c4d324f8 963 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 812 959 4.8E-54 T 29-03-2018 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 GBCGDNIH2_RS10770 efede833ae394a0e02822204c4d324f8 963 Pfam PF02779 Transketolase, pyrimidine binding domain 614 809 5.5E-63 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain GBCGDNIH2_RS10770 efede833ae394a0e02822204c4d324f8 963 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 11 958 0.0 T 29-03-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 GBCGDNIH2_RS10770 efede833ae394a0e02822204c4d324f8 963 SUPERFAMILY SSF52518 597 814 3.36E-49 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold GBCGDNIH2_RS10770 efede833ae394a0e02822204c4d324f8 963 Gene3D G3DSA:1.10.287.1150 98 180 7.4E-24 T 29-03-2018 GBCGDNIH2_RS10770 efede833ae394a0e02822204c4d324f8 963 SUPERFAMILY SSF52518 136 563 2.03E-88 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold GBCGDNIH2_RS01105 5c1bc4508c472c6c351b332debfd1533 95 Pfam PF01206 Sulfurtransferase TusA 5 73 9.7E-24 T 29-03-2018 IPR001455 TusA-like domain GBCGDNIH2_RS01105 5c1bc4508c472c6c351b332debfd1533 95 SUPERFAMILY SSF64307 5 73 5.62E-23 T 29-03-2018 IPR001455 TusA-like domain GBCGDNIH2_RS01105 5c1bc4508c472c6c351b332debfd1533 95 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 6 30 - T 29-03-2018 IPR001455 TusA-like domain GBCGDNIH2_RS01105 5c1bc4508c472c6c351b332debfd1533 95 Gene3D G3DSA:3.30.110.40 1 74 5.0E-26 T 29-03-2018 IPR001455 TusA-like domain GBCGDNIH2_RS01005 b16755644632836f55b2846650ba86be 174 Gene3D G3DSA:3.90.80.10 3 174 4.2E-56 T 29-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 GBCGDNIH2_RS01005 b16755644632836f55b2846650ba86be 174 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 14 173 36.771 T 29-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 GBCGDNIH2_RS01005 b16755644632836f55b2846650ba86be 174 SUPERFAMILY SSF50324 6 172 8.11E-66 T 29-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 GBCGDNIH2_RS01005 b16755644632836f55b2846650ba86be 174 Pfam PF00719 Inorganic pyrophosphatase 18 171 8.6E-56 T 29-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 GBCGDNIH2_RS05170 f11abc57b6bca4f1c482003b9de7b740 107 SUPERFAMILY SSF141000 3 105 1.83E-20 T 29-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 GBCGDNIH2_RS05170 f11abc57b6bca4f1c482003b9de7b740 107 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 2 107 20.167 T 29-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 GBCGDNIH2_RS05170 f11abc57b6bca4f1c482003b9de7b740 107 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 20 102 8.8E-18 T 29-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 GBCGDNIH2_RS05170 f11abc57b6bca4f1c482003b9de7b740 107 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 7 107 2.5E-18 T 29-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 GBCGDNIH2_RS02600 be80cd7e8dd6b7f189b24705ac02a887 438 Gene3D G3DSA:1.10.287.130 197 276 1.4E-6 T 29-03-2018 GBCGDNIH2_RS02600 be80cd7e8dd6b7f189b24705ac02a887 438 SMART SM00387 322 427 9.6E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS02600 be80cd7e8dd6b7f189b24705ac02a887 438 SUPERFAMILY SSF47384 202 275 1.63E-6 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GBCGDNIH2_RS02600 be80cd7e8dd6b7f189b24705ac02a887 438 Gene3D G3DSA:3.30.565.10 285 429 3.8E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS02600 be80cd7e8dd6b7f189b24705ac02a887 438 SUPERFAMILY SSF55874 292 427 6.16E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS02600 be80cd7e8dd6b7f189b24705ac02a887 438 PRINTS PR00344 Bacterial sensor protein C-terminal signature 411 424 1.1E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS02600 be80cd7e8dd6b7f189b24705ac02a887 438 PRINTS PR00344 Bacterial sensor protein C-terminal signature 357 371 1.1E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS02600 be80cd7e8dd6b7f189b24705ac02a887 438 PRINTS PR00344 Bacterial sensor protein C-terminal signature 387 405 1.1E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS02600 be80cd7e8dd6b7f189b24705ac02a887 438 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 325 426 7.7E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS05220 e90cd5d690538f34e01bcdb61260f894 293 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 8 156 8.6E-35 T 29-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 GBCGDNIH2_RS05220 e90cd5d690538f34e01bcdb61260f894 293 PIRSF PIRSF000103 1 290 2.0E-64 T 29-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 GBCGDNIH2_RS05220 e90cd5d690538f34e01bcdb61260f894 293 Gene3D G3DSA:1.10.1040.10 159 288 1.4E-30 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 GBCGDNIH2_RS05220 e90cd5d690538f34e01bcdb61260f894 293 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 162 280 2.8E-30 T 29-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 GBCGDNIH2_RS05220 e90cd5d690538f34e01bcdb61260f894 293 Gene3D G3DSA:3.40.50.720 1 158 5.5E-28 T 29-03-2018 GBCGDNIH2_RS05220 e90cd5d690538f34e01bcdb61260f894 293 SUPERFAMILY SSF51735 7 157 3.12E-36 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS05220 e90cd5d690538f34e01bcdb61260f894 293 SUPERFAMILY SSF48179 160 285 7.25E-34 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 GBCGDNIH2_RS07880 07660dc454f244c8cd3481e717e2cc65 296 Gene3D G3DSA:3.40.50.1000 147 286 1.0E-19 T 29-03-2018 IPR023214 HAD-like domain GBCGDNIH2_RS07880 07660dc454f244c8cd3481e717e2cc65 296 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 83 287 2.7E-49 T 29-03-2018 GBCGDNIH2_RS07880 07660dc454f244c8cd3481e717e2cc65 296 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 90 259 1.0E-21 T 29-03-2018 GBCGDNIH2_RS07880 07660dc454f244c8cd3481e717e2cc65 296 SUPERFAMILY SSF56784 87 294 9.09E-37 T 29-03-2018 IPR023214 HAD-like domain GBCGDNIH2_RS07880 07660dc454f244c8cd3481e717e2cc65 296 Gene3D G3DSA:1.10.150.210 101 146 3.0E-12 T 29-03-2018 IPR023190 Phosphoserine phosphatase, domain 2 GO:0004647|GO:0006564 KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3|Reactome: R-HSA-977347 GBCGDNIH2_RS07880 07660dc454f244c8cd3481e717e2cc65 296 Pfam PF12710 haloacid dehalogenase-like hydrolase 92 258 3.5E-11 T 29-03-2018 GBCGDNIH2_RS08230 08aeaa9ccb128fa9c41206f9249e94cc 457 Pfam PF11041 Protein of unknown function (DUF2612) 340 419 1.7E-12 T 29-03-2018 IPR021283 Protein of unknown function DUF2612 GBCGDNIH2_RS08230 08aeaa9ccb128fa9c41206f9249e94cc 457 Pfam PF11041 Protein of unknown function (DUF2612) 273 334 4.1E-8 T 29-03-2018 IPR021283 Protein of unknown function DUF2612 GBCGDNIH2_RS08230 08aeaa9ccb128fa9c41206f9249e94cc 457 Gene3D G3DSA:2.60.120.260 59 220 1.1E-7 T 29-03-2018 IPR008979 Galactose-binding domain-like GBCGDNIH2_RS04230 9a954ed6ecbcb867eba9bdc2dd2bf640 512 Pfam PF04715 Anthranilate synthase component I, N terminal region 32 177 3.7E-30 T 29-03-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 GBCGDNIH2_RS04230 9a954ed6ecbcb867eba9bdc2dd2bf640 512 Gene3D G3DSA:3.60.120.10 21 501 3.8E-160 T 29-03-2018 IPR005801 ADC synthase GO:0009058 GBCGDNIH2_RS04230 9a954ed6ecbcb867eba9bdc2dd2bf640 512 Pfam PF00425 chorismate binding enzyme 235 489 8.4E-97 T 29-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal GBCGDNIH2_RS04230 9a954ed6ecbcb867eba9bdc2dd2bf640 512 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 31 497 6.6E-167 T 29-03-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 GBCGDNIH2_RS04230 9a954ed6ecbcb867eba9bdc2dd2bf640 512 SUPERFAMILY SSF56322 23 496 1.31E-151 T 29-03-2018 IPR005801 ADC synthase GO:0009058 GBCGDNIH2_RS04230 9a954ed6ecbcb867eba9bdc2dd2bf640 512 PRINTS PR00095 Anthranilate synthase component I signature 446 460 8.5E-23 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 GBCGDNIH2_RS04230 9a954ed6ecbcb867eba9bdc2dd2bf640 512 PRINTS PR00095 Anthranilate synthase component I signature 351 364 8.5E-23 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 GBCGDNIH2_RS04230 9a954ed6ecbcb867eba9bdc2dd2bf640 512 PRINTS PR00095 Anthranilate synthase component I signature 431 445 8.5E-23 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 GBCGDNIH2_RS04230 9a954ed6ecbcb867eba9bdc2dd2bf640 512 PRINTS PR00095 Anthranilate synthase component I signature 337 350 8.5E-23 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 GBCGDNIH2_RS01045 f255002b33c65c4dc534258245b0c944 320 Gene3D G3DSA:3.20.20.220 29 318 5.0E-91 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like GBCGDNIH2_RS01045 f255002b33c65c4dc534258245b0c944 320 SUPERFAMILY SSF51730 38 313 5.69E-95 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like GBCGDNIH2_RS01045 f255002b33c65c4dc534258245b0c944 320 Pfam PF02219 Methylenetetrahydrofolate reductase 37 310 3.6E-90 T 29-03-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 GBCGDNIH2_RS01045 f255002b33c65c4dc534258245b0c944 320 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 40 310 1.3E-100 T 29-03-2018 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841 GBCGDNIH2_RS05380 590c079437cf9cc921bc7fa7a5c27c5d 304 SUPERFAMILY SSF54814 185 300 1.83E-35 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 GBCGDNIH2_RS05380 590c079437cf9cc921bc7fa7a5c27c5d 304 Pfam PF07650 KH domain 212 283 9.9E-14 T 29-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS05380 590c079437cf9cc921bc7fa7a5c27c5d 304 TIGRFAM TIGR00436 era: GTP-binding protein Era 11 283 8.6E-66 T 29-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS05380 590c079437cf9cc921bc7fa7a5c27c5d 304 Gene3D G3DSA:3.30.300.20 189 303 3.2E-35 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta GBCGDNIH2_RS05380 590c079437cf9cc921bc7fa7a5c27c5d 304 SUPERFAMILY SSF52540 12 186 1.34E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS05380 590c079437cf9cc921bc7fa7a5c27c5d 304 Gene3D G3DSA:3.40.50.300 11 181 1.5E-26 T 29-03-2018 GBCGDNIH2_RS05380 590c079437cf9cc921bc7fa7a5c27c5d 304 Hamap MF_00367 GTPase Era [era]. 7 300 31.384 T 29-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS05380 590c079437cf9cc921bc7fa7a5c27c5d 304 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 168 1.1E-19 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 GBCGDNIH2_RS05380 590c079437cf9cc921bc7fa7a5c27c5d 304 Pfam PF01926 50S ribosome-binding GTPase 12 129 1.5E-20 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 GBCGDNIH2_RS09595 85fe97474fde43a931389021702a0b06 248 Pfam PF00005 ABC transporter 25 178 9.0E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GBCGDNIH2_RS09595 85fe97474fde43a931389021702a0b06 248 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 225 247 1.3E-7 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal GBCGDNIH2_RS09595 85fe97474fde43a931389021702a0b06 248 Gene3D G3DSA:3.40.50.300 3 248 2.5E-56 T 29-03-2018 GBCGDNIH2_RS09595 85fe97474fde43a931389021702a0b06 248 SUPERFAMILY SSF52540 7 246 8.71E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS09595 85fe97474fde43a931389021702a0b06 248 TIGRFAM TIGR03411 urea_trans_UrtD: urea ABC transporter, ATP-binding protein UrtD 8 248 3.5E-114 T 29-03-2018 IPR017781 ABC transporter, urea, ATP-binding protein, UrtD GBCGDNIH2_RS09315 d2292160aef56064547d2dfcd4dd9d48 314 Gene3D G3DSA:3.40.50.720 17 152 1.9E-17 T 29-03-2018 GBCGDNIH2_RS09315 d2292160aef56064547d2dfcd4dd9d48 314 SUPERFAMILY SSF51735 20 242 1.39E-28 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS09315 d2292160aef56064547d2dfcd4dd9d48 314 Gene3D G3DSA:3.40.50.720 153 310 8.6E-7 T 29-03-2018 GBCGDNIH2_RS09315 d2292160aef56064547d2dfcd4dd9d48 314 Pfam PF05368 NmrA-like family 22 235 8.0E-18 T 29-03-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 GBCGDNIH2_RS08625 a34201d9e1143a8bb813eec7cc13864a 342 PIRSF PIRSF002849 5 342 4.1E-113 T 29-03-2018 GBCGDNIH2_RS08625 a34201d9e1143a8bb813eec7cc13864a 342 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 62 195 5.6E-57 T 29-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 GBCGDNIH2_RS08625 a34201d9e1143a8bb813eec7cc13864a 342 SUPERFAMILY SSF52540 33 318 2.7E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS08625 a34201d9e1143a8bb813eec7cc13864a 342 SMART SM00382 59 203 0.0048 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS08625 a34201d9e1143a8bb813eec7cc13864a 342 Gene3D G3DSA:3.40.50.300 43 212 6.1E-25 T 29-03-2018 GBCGDNIH2_RS08625 a34201d9e1143a8bb813eec7cc13864a 342 Gene3D G3DSA:1.10.8.300 225 341 4.1E-27 T 29-03-2018 GBCGDNIH2_RS11335 f5a498d11228929bd5d5b16cfb9dcb01 374 Hamap MF_01665 Heme A synthase [ctaA]. 31 361 24.828 T 29-03-2018 IPR023754 Heme A synthase, type 2 GO:0006784|GO:0016020|GO:0016627|GO:0055114 Reactome: R-HSA-189451 GBCGDNIH2_RS11335 f5a498d11228929bd5d5b16cfb9dcb01 374 Pfam PF02628 Cytochrome oxidase assembly protein 35 351 1.0E-101 T 29-03-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 GBCGDNIH2_RS05285 5cd081eef100a745209d1df403bb6212 259 PIRSF PIRSF006241 1 259 3.7E-96 T 29-03-2018 IPR026040 Hydroxypyruvate isomerase-like KEGG: 00630+5.3.1.22 GBCGDNIH2_RS05285 5cd081eef100a745209d1df403bb6212 259 SUPERFAMILY SSF51658 1 255 4.06E-69 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain GBCGDNIH2_RS05285 5cd081eef100a745209d1df403bb6212 259 Gene3D G3DSA:3.20.20.150 2 258 9.7E-52 T 29-03-2018 GBCGDNIH2_RS05285 5cd081eef100a745209d1df403bb6212 259 Pfam PF01261 Xylose isomerase-like TIM barrel 21 219 4.9E-29 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain GBCGDNIH2_RS12490 40bcca01c308b64fbe6e5be821941a85 513 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 2 495 6.2E-119 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ GBCGDNIH2_RS12490 40bcca01c308b64fbe6e5be821941a85 513 Pfam PF03023 MviN-like protein 26 458 2.8E-109 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ GBCGDNIH2_RS12490 40bcca01c308b64fbe6e5be821941a85 513 PRINTS PR01806 Virulence factor MviN signature 50 66 1.6E-58 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ GBCGDNIH2_RS12490 40bcca01c308b64fbe6e5be821941a85 513 PRINTS PR01806 Virulence factor MviN signature 131 155 1.6E-58 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ GBCGDNIH2_RS12490 40bcca01c308b64fbe6e5be821941a85 513 PRINTS PR01806 Virulence factor MviN signature 257 283 1.6E-58 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ GBCGDNIH2_RS12490 40bcca01c308b64fbe6e5be821941a85 513 PRINTS PR01806 Virulence factor MviN signature 31 50 1.6E-58 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ GBCGDNIH2_RS12490 40bcca01c308b64fbe6e5be821941a85 513 PRINTS PR01806 Virulence factor MviN signature 155 176 1.6E-58 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ GBCGDNIH2_RS12490 40bcca01c308b64fbe6e5be821941a85 513 PRINTS PR01806 Virulence factor MviN signature 355 374 1.6E-58 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ GBCGDNIH2_RS12490 40bcca01c308b64fbe6e5be821941a85 513 PRINTS PR01806 Virulence factor MviN signature 407 424 1.6E-58 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ GBCGDNIH2_RS12490 40bcca01c308b64fbe6e5be821941a85 513 PIRSF PIRSF002869 1 511 2.7E-147 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ GBCGDNIH2_RS12490 40bcca01c308b64fbe6e5be821941a85 513 Hamap MF_02078 Probable lipid II flippase MurJ [murJ]. 1 465 18.581 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ GBCGDNIH2_RS10405 9bbffbbd828af26e64b55eaddc0f0aa9 177 PRINTS PR00604 Class IA and IB cytochrome C signature 104 114 2.1E-9 T 29-03-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS10405 9bbffbbd828af26e64b55eaddc0f0aa9 177 PRINTS PR00604 Class IA and IB cytochrome C signature 74 81 2.1E-9 T 29-03-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS10405 9bbffbbd828af26e64b55eaddc0f0aa9 177 PRINTS PR00604 Class IA and IB cytochrome C signature 137 147 2.1E-9 T 29-03-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS10405 9bbffbbd828af26e64b55eaddc0f0aa9 177 PRINTS PR00604 Class IA and IB cytochrome C signature 118 134 2.1E-9 T 29-03-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS10405 9bbffbbd828af26e64b55eaddc0f0aa9 177 PRINTS PR00604 Class IA and IB cytochrome C signature 154 162 2.1E-9 T 29-03-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS10405 9bbffbbd828af26e64b55eaddc0f0aa9 177 Pfam PF00034 Cytochrome c 65 161 4.1E-6 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 GBCGDNIH2_RS10405 9bbffbbd828af26e64b55eaddc0f0aa9 177 SUPERFAMILY SSF46626 61 161 3.44E-26 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 GBCGDNIH2_RS10405 9bbffbbd828af26e64b55eaddc0f0aa9 177 Gene3D G3DSA:1.10.760.10 60 176 6.1E-22 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 GBCGDNIH2_RS03480 7176da4473ea84640e0f11a07776fb86 536 Gene3D G3DSA:3.40.50.2000 272 534 9.3E-27 T 29-03-2018 GBCGDNIH2_RS03480 7176da4473ea84640e0f11a07776fb86 536 Gene3D G3DSA:1.25.40.10 2 171 1.4E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS03480 7176da4473ea84640e0f11a07776fb86 536 SUPERFAMILY SSF53756 261 483 2.28E-23 T 29-03-2018 GBCGDNIH2_RS03480 7176da4473ea84640e0f11a07776fb86 536 Gene3D G3DSA:1.25.40.10 172 239 3.3E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS03480 7176da4473ea84640e0f11a07776fb86 536 SUPERFAMILY SSF48452 133 237 1.11E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS03480 7176da4473ea84640e0f11a07776fb86 536 SMART SM00028 207 240 150.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 GBCGDNIH2_RS03480 7176da4473ea84640e0f11a07776fb86 536 SMART SM00028 173 206 0.037 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 GBCGDNIH2_RS07675 24ce9fa35e3e5bfb2271702d0c178def 297 Gene3D G3DSA:3.60.110.10 2 281 4.4E-46 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 GBCGDNIH2_RS07675 24ce9fa35e3e5bfb2271702d0c178def 297 Pfam PF00795 Carbon-nitrogen hydrolase 17 216 1.4E-19 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 GBCGDNIH2_RS07675 24ce9fa35e3e5bfb2271702d0c178def 297 SUPERFAMILY SSF56317 3 277 7.59E-54 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 GBCGDNIH2_RS03890 0fed807407de6199f304aef069e229b7 192 SUPERFAMILY SSF88659 95 156 4.58E-15 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GBCGDNIH2_RS03890 0fed807407de6199f304aef069e229b7 192 Gene3D G3DSA:1.10.1740.10 2 99 4.8E-14 T 29-03-2018 GBCGDNIH2_RS03890 0fed807407de6199f304aef069e229b7 192 SUPERFAMILY SSF88946 4 85 8.63E-17 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GBCGDNIH2_RS03890 0fed807407de6199f304aef069e229b7 192 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 17 154 3.8E-23 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GBCGDNIH2_RS03890 0fed807407de6199f304aef069e229b7 192 Pfam PF08281 Sigma-70, region 4 102 153 1.7E-16 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GBCGDNIH2_RS03890 0fed807407de6199f304aef069e229b7 192 Gene3D G3DSA:1.10.10.10 100 187 1.8E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS03890 0fed807407de6199f304aef069e229b7 192 Pfam PF04542 Sigma-70 region 2 14 75 1.3E-12 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GBCGDNIH2_RS03315 05e9fa448fe42f821f476b8b08a09b7a 598 SUPERFAMILY SSF50998 32 595 8.37E-170 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily GBCGDNIH2_RS03315 05e9fa448fe42f821f476b8b08a09b7a 598 ProSitePatterns PS00364 Bacterial quinoprotein dehydrogenases signature 2. 263 284 - T 29-03-2018 IPR001479 Quinoprotein dehydrogenase, conserved site GO:0030288|GO:0055114 GBCGDNIH2_RS03315 05e9fa448fe42f821f476b8b08a09b7a 598 Pfam PF13360 PQQ-like domain 88 219 3.2E-9 T 29-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat GBCGDNIH2_RS03315 05e9fa448fe42f821f476b8b08a09b7a 598 Pfam PF01011 PQQ enzyme repeat 502 534 2.1E-6 T 29-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat GBCGDNIH2_RS03315 05e9fa448fe42f821f476b8b08a09b7a 598 Gene3D G3DSA:2.140.10.10 28 598 7.6E-120 T 29-03-2018 GBCGDNIH2_RS03315 05e9fa448fe42f821f476b8b08a09b7a 598 TIGRFAM TIGR03075 PQQ_enz_alc_DH: PQQ-dependent dehydrogenase, methanol/ethanol family 24 556 9.2E-220 T 29-03-2018 IPR017512 PQQ-dependent dehydrogenase, methanol/ethanol family GO:0005509|GO:0016020|GO:0016614|GO:0055114 GBCGDNIH2_RS03315 05e9fa448fe42f821f476b8b08a09b7a 598 SMART SM00564 444 487 160.0 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat GBCGDNIH2_RS03315 05e9fa448fe42f821f476b8b08a09b7a 598 SMART SM00564 267 315 32.0 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat GBCGDNIH2_RS03315 05e9fa448fe42f821f476b8b08a09b7a 598 SMART SM00564 85 118 95.0 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat GBCGDNIH2_RS03315 05e9fa448fe42f821f476b8b08a09b7a 598 SMART SM00564 496 528 9.8E-4 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat GBCGDNIH2_RS03315 05e9fa448fe42f821f476b8b08a09b7a 598 SMART SM00564 183 220 130.0 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat GBCGDNIH2_RS03315 05e9fa448fe42f821f476b8b08a09b7a 598 SMART SM00564 137 169 0.042 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat GBCGDNIH2_RS01425 d8ff0ed8e1dfe00353b962b343fb8759 504 SUPERFAMILY SSF103473 25 491 1.7E-73 T 29-03-2018 IPR020846 Major facilitator superfamily domain GBCGDNIH2_RS01425 d8ff0ed8e1dfe00353b962b343fb8759 504 Pfam PF00083 Sugar (and other) transporter 84 464 4.3E-40 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 GBCGDNIH2_RS01425 d8ff0ed8e1dfe00353b962b343fb8759 504 Gene3D G3DSA:1.20.1250.20 280 493 6.5E-23 T 29-03-2018 GBCGDNIH2_RS01425 d8ff0ed8e1dfe00353b962b343fb8759 504 Gene3D G3DSA:1.20.1250.20 34 264 1.0E-30 T 29-03-2018 GBCGDNIH2_RS04710 53473cc65ebc9617f7e665f82854a10e 81 Gene3D G3DSA:1.10.260.40 5 61 0.0011 T 29-03-2018 GBCGDNIH2_RS06485 dc9870f0b446484e728ed16f779ebae7 390 Pfam PF14238 Domain of unknown function (DUF4340) 76 272 9.1E-14 T 29-03-2018 IPR025641 Domain of unknown function DUF4340 GBCGDNIH2_RS11915 400e0ffd79127ce7fd1b287c2cf414f0 254 SUPERFAMILY SSF52540 5 234 2.86E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS11915 400e0ffd79127ce7fd1b287c2cf414f0 254 Pfam PF00005 ABC transporter 23 164 3.8E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GBCGDNIH2_RS11915 400e0ffd79127ce7fd1b287c2cf414f0 254 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GBCGDNIH2_RS11915 400e0ffd79127ce7fd1b287c2cf414f0 254 SMART SM00382 31 214 1.5E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS11915 400e0ffd79127ce7fd1b287c2cf414f0 254 Gene3D G3DSA:3.40.50.300 1 221 1.2E-54 T 29-03-2018 GBCGDNIH2_RS12550 91406bff301b37d82bf31ec5fbcbcf09 376 Gene3D G3DSA:1.20.1170.10 66 375 4.6E-8 T 29-03-2018 GBCGDNIH2_RS12550 91406bff301b37d82bf31ec5fbcbcf09 376 Pfam PF09731 Mitochondrial inner membrane protein 315 376 6.5E-7 T 29-03-2018 IPR019133 Mitochondrial inner membrane protein Mitofilin Reactome: R-HSA-8949613 GBCGDNIH2_RS01220 ba28629a437f72aba7d267da5a517a02 322 Pfam PF01370 NAD dependent epimerase/dehydratase family 8 202 1.1E-21 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 GBCGDNIH2_RS01220 ba28629a437f72aba7d267da5a517a02 322 Gene3D G3DSA:3.40.50.720 1 316 5.6E-51 T 29-03-2018 GBCGDNIH2_RS01220 ba28629a437f72aba7d267da5a517a02 322 SUPERFAMILY SSF51735 271 296 2.49E-53 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS01220 ba28629a437f72aba7d267da5a517a02 322 SUPERFAMILY SSF51735 5 244 2.49E-53 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS02345 dd4cb3d2216b9ff1069201baa34cbcef 465 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 262 389 6.1E-10 T 29-03-2018 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 GBCGDNIH2_RS02345 dd4cb3d2216b9ff1069201baa34cbcef 465 Gene3D G3DSA:3.40.50.2000 247 438 5.5E-28 T 29-03-2018 GBCGDNIH2_RS02345 dd4cb3d2216b9ff1069201baa34cbcef 465 TIGRFAM TIGR04414 hepto_Aah_TibC: autotransporter strand-loop-strand O-heptosyltransferase 46 434 6.7E-187 T 29-03-2018 IPR030929 Glycosyltransferase Aah/TibC GO:0016757 GBCGDNIH2_RS02345 dd4cb3d2216b9ff1069201baa34cbcef 465 SUPERFAMILY SSF53756 148 433 4.39E-25 T 29-03-2018 GBCGDNIH2_RS03460 305e54cd32bce2cbcff84353080a0c0b 62 Pfam PF11154 Protein of unknown function (DUF2934) 8 42 1.3E-14 T 29-03-2018 IPR021327 Protein of unknown function DUF2934 GBCGDNIH2_RS11650 ebae0870b1562f0b47b97c1cf07655c1 302 SUPERFAMILY SSF111331 15 302 5.67E-63 T 29-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain GBCGDNIH2_RS11650 ebae0870b1562f0b47b97c1cf07655c1 302 Pfam PF00781 Diacylglycerol kinase catalytic domain 14 128 4.9E-28 T 29-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 GBCGDNIH2_RS11650 ebae0870b1562f0b47b97c1cf07655c1 302 Gene3D G3DSA:3.40.50.10330 6 130 3.4E-28 T 29-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 GBCGDNIH2_RS11650 ebae0870b1562f0b47b97c1cf07655c1 302 SMART SM00046 13 130 5.2E-7 T 29-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 GBCGDNIH2_RS07930 262323b79adcfdbacbbbf11b641a7955 560 Pfam PF13372 Alginate export 141 543 1.2E-32 T 29-03-2018 IPR025388 Alginate export domain GBCGDNIH2_RS05480 50dd96bb7e35fb4d177d2165c6d329d7 70 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 55 20.785 T 29-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS05480 50dd96bb7e35fb4d177d2165c6d329d7 70 Pfam PF01783 Ribosomal L32p protein family 2 55 4.3E-27 T 29-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS05480 50dd96bb7e35fb4d177d2165c6d329d7 70 SUPERFAMILY SSF57829 1 54 2.01E-23 T 29-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 GBCGDNIH2_RS05480 50dd96bb7e35fb4d177d2165c6d329d7 70 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 54 3.6E-26 T 29-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS04855 c0ac5b827feae9dd7d7326ff82716d8c 2056 Pfam PF06791 Prophage tail length tape measure protein 292 486 2.0E-15 T 29-03-2018 IPR009628 Bacteriophage lambda, GpH, tail tape measure, N-terminal GBCGDNIH2_RS04855 c0ac5b827feae9dd7d7326ff82716d8c 2056 Gene3D G3DSA:1.10.530.10 606 772 6.1E-21 T 29-03-2018 GBCGDNIH2_RS04855 c0ac5b827feae9dd7d7326ff82716d8c 2056 Gene3D G3DSA:1.20.120.20 1042 1314 3.3E-4 T 29-03-2018 GBCGDNIH2_RS04855 c0ac5b827feae9dd7d7326ff82716d8c 2056 Pfam PF01464 Transglycosylase SLT domain 647 735 8.1E-10 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 GBCGDNIH2_RS04855 c0ac5b827feae9dd7d7326ff82716d8c 2056 SUPERFAMILY SSF53955 636 763 1.22E-19 T 29-03-2018 IPR023346 Lysozyme-like domain GBCGDNIH2_RS11000 0cf697aabe6a1f8aa2de054c063ee7ad 281 Gene3D G3DSA:2.40.50.110 211 270 0.006 T 29-03-2018 GBCGDNIH2_RS11000 0cf697aabe6a1f8aa2de054c063ee7ad 281 Gene3D G3DSA:2.40.50.110 49 209 3.5E-5 T 29-03-2018 GBCGDNIH2_RS11000 0cf697aabe6a1f8aa2de054c063ee7ad 281 Pfam PF06347 Bacterial SH3 domain 154 208 5.7E-15 T 29-03-2018 IPR010466 Protein of unknown function DUF1058 GBCGDNIH2_RS11000 0cf697aabe6a1f8aa2de054c063ee7ad 281 Pfam PF06347 Bacterial SH3 domain 219 272 3.8E-10 T 29-03-2018 IPR010466 Protein of unknown function DUF1058 GBCGDNIH2_RS04065 386cf44b39b48229c50f2ee0c60cfb05 511 SUPERFAMILY SSF56801 17 506 9.81E-126 T 29-03-2018 GBCGDNIH2_RS04065 386cf44b39b48229c50f2ee0c60cfb05 511 Pfam PF13193 AMP-binding enzyme C-terminal domain 422 497 9.5E-14 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain GBCGDNIH2_RS04065 386cf44b39b48229c50f2ee0c60cfb05 511 Gene3D G3DSA:3.30.300.30 408 508 1.4E-23 T 29-03-2018 GBCGDNIH2_RS04065 386cf44b39b48229c50f2ee0c60cfb05 511 Gene3D G3DSA:2.30.38.10 325 406 9.6E-20 T 29-03-2018 GBCGDNIH2_RS04065 386cf44b39b48229c50f2ee0c60cfb05 511 Gene3D G3DSA:3.40.50.980 6 170 2.9E-30 T 29-03-2018 GBCGDNIH2_RS04065 386cf44b39b48229c50f2ee0c60cfb05 511 Gene3D G3DSA:3.40.50.980 171 324 6.4E-39 T 29-03-2018 GBCGDNIH2_RS04065 386cf44b39b48229c50f2ee0c60cfb05 511 Pfam PF00501 AMP-binding enzyme 18 413 1.7E-81 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 GBCGDNIH2_RS04065 386cf44b39b48229c50f2ee0c60cfb05 511 ProSitePatterns PS00455 Putative AMP-binding domain signature. 166 177 - T 29-03-2018 IPR020845 AMP-binding, conserved site GBCGDNIH2_RS05415 9997c560486b0face9062162f211588e 109 SUPERFAMILY SSF103481 6 105 2.48E-21 T 29-03-2018 GBCGDNIH2_RS05415 9997c560486b0face9062162f211588e 109 Pfam PF00893 Small Multidrug Resistance protein 6 94 1.4E-28 T 29-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 GBCGDNIH2_RS12270 f34ca9a5259e04e1396fac18bca0d31c 343 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 9 336 2.0E-100 T 29-03-2018 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 GBCGDNIH2_RS12270 f34ca9a5259e04e1396fac18bca0d31c 343 Gene3D G3DSA:3.20.20.140 262 343 1.8E-27 T 29-03-2018 GBCGDNIH2_RS12270 f34ca9a5259e04e1396fac18bca0d31c 343 SUPERFAMILY SSF51556 9 339 4.76E-86 T 29-03-2018 IPR032466 Metal-dependent hydrolase GBCGDNIH2_RS12270 f34ca9a5259e04e1396fac18bca0d31c 343 Gene3D G3DSA:3.20.20.140 5 261 4.6E-75 T 29-03-2018 GBCGDNIH2_RS03275 1ef356483600c23eb2c638010f1e2d52 359 TIGRFAM TIGR04021 LLM_DMSO2_sfnG: dimethyl sulfone monooxygenase SfnG 4 353 3.1E-190 T 29-03-2018 IPR024014 Dimethyl sulphone monooxygenase SfnG GBCGDNIH2_RS03275 1ef356483600c23eb2c638010f1e2d52 359 Gene3D G3DSA:3.20.20.30 1 356 1.7E-80 T 29-03-2018 GBCGDNIH2_RS03275 1ef356483600c23eb2c638010f1e2d52 359 Pfam PF00296 Luciferase-like monooxygenase 5 324 3.2E-77 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 GBCGDNIH2_RS03275 1ef356483600c23eb2c638010f1e2d52 359 SUPERFAMILY SSF51679 3 350 6.15E-92 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 GBCGDNIH2_RS08550 80257064e5ad44a6ae3b06eafba1688e 615 Gene3D G3DSA:3.40.50.300 2 221 1.2E-26 T 29-03-2018 GBCGDNIH2_RS08550 80257064e5ad44a6ae3b06eafba1688e 615 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 198 581 9.6E-97 T 29-03-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 GBCGDNIH2_RS08550 80257064e5ad44a6ae3b06eafba1688e 615 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 31 49 1.2E-6 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 GBCGDNIH2_RS08550 80257064e5ad44a6ae3b06eafba1688e 615 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 10 30 1.2E-6 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 GBCGDNIH2_RS08550 80257064e5ad44a6ae3b06eafba1688e 615 Pfam PF07670 Nucleoside recognition 453 585 1.4E-25 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 GBCGDNIH2_RS08550 80257064e5ad44a6ae3b06eafba1688e 615 Pfam PF07670 Nucleoside recognition 287 380 9.9E-11 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 GBCGDNIH2_RS08550 80257064e5ad44a6ae3b06eafba1688e 615 SUPERFAMILY SSF52540 7 182 1.87E-33 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS08550 80257064e5ad44a6ae3b06eafba1688e 615 Pfam PF02421 Ferrous iron transport protein B 9 167 3.2E-50 T 29-03-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 GBCGDNIH2_RS08550 80257064e5ad44a6ae3b06eafba1688e 615 Pfam PF07664 Ferrous iron transport protein B C terminus 398 448 4.2E-16 T 29-03-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 GBCGDNIH2_RS03125 907f466be37bbb98e8a56a17a9135b5e 574 Gene3D G3DSA:3.40.50.300 323 570 1.2E-76 T 29-03-2018 GBCGDNIH2_RS03125 907f466be37bbb98e8a56a17a9135b5e 574 ProSitePatterns PS00211 ABC transporters family signature. 466 480 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GBCGDNIH2_RS03125 907f466be37bbb98e8a56a17a9135b5e 574 SUPERFAMILY SSF52540 327 564 2.27E-92 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS03125 907f466be37bbb98e8a56a17a9135b5e 574 Pfam PF00005 ABC transporter 345 494 6.0E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GBCGDNIH2_RS03125 907f466be37bbb98e8a56a17a9135b5e 574 Gene3D G3DSA:1.20.1560.10 1 314 4.1E-52 T 29-03-2018 GBCGDNIH2_RS03125 907f466be37bbb98e8a56a17a9135b5e 574 SUPERFAMILY SSF90123 3 312 1.7E-58 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 GBCGDNIH2_RS03125 907f466be37bbb98e8a56a17a9135b5e 574 SMART SM00382 354 546 1.8E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS03125 907f466be37bbb98e8a56a17a9135b5e 574 Pfam PF00664 ABC transporter transmembrane region 4 277 3.5E-36 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 GBCGDNIH2_RS01060 b2c1da2e1c3e63daf1054c862f4e0f51 496 Gene3D G3DSA:3.30.420.150 125 301 7.9E-36 T 29-03-2018 GBCGDNIH2_RS01060 b2c1da2e1c3e63daf1054c862f4e0f51 496 SUPERFAMILY SSF53067 135 305 7.34E-34 T 29-03-2018 GBCGDNIH2_RS01060 b2c1da2e1c3e63daf1054c862f4e0f51 496 SUPERFAMILY SSF53067 11 133 1.81E-29 T 29-03-2018 GBCGDNIH2_RS01060 b2c1da2e1c3e63daf1054c862f4e0f51 496 Gene3D G3DSA:3.30.420.40 5 124 6.7E-33 T 29-03-2018 GBCGDNIH2_RS01060 b2c1da2e1c3e63daf1054c862f4e0f51 496 SUPERFAMILY SSF109604 322 465 6.59E-6 T 29-03-2018 GBCGDNIH2_RS01060 b2c1da2e1c3e63daf1054c862f4e0f51 496 Pfam PF02541 Ppx/GppA phosphatase family 28 302 2.0E-40 T 29-03-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 GBCGDNIH2_RS00020 d7341810ab636400d480ac8bf1dbdb28 197 Pfam PF02545 Maf-like protein 2 191 1.4E-35 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 GBCGDNIH2_RS00020 d7341810ab636400d480ac8bf1dbdb28 197 PIRSF PIRSF006305 1 197 4.6E-37 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 GBCGDNIH2_RS00020 d7341810ab636400d480ac8bf1dbdb28 197 Gene3D G3DSA:3.90.950.10 1 197 3.9E-46 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like GBCGDNIH2_RS00020 d7341810ab636400d480ac8bf1dbdb28 197 SUPERFAMILY SSF52972 1 191 1.18E-45 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like GBCGDNIH2_RS00020 d7341810ab636400d480ac8bf1dbdb28 197 Hamap MF_00528 Septum formation protein Maf [maf]. 2 196 22.557 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 GBCGDNIH2_RS04510 cfd634865c756268a47cb54a2eb95cea 158 Pfam PF14347 Domain of unknown function (DUF4399) 65 158 7.6E-34 T 29-03-2018 IPR025512 Domain of unknown function DUF4399 GBCGDNIH2_RS11470 2a9effac405d128392af8789d6800edd 320 SUPERFAMILY SSF55048 132 207 7.98E-15 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 GBCGDNIH2_RS11470 2a9effac405d128392af8789d6800edd 320 Pfam PF00698 Acyl transferase domain 6 286 2.5E-42 T 29-03-2018 IPR014043 Acyl transferase GBCGDNIH2_RS11470 2a9effac405d128392af8789d6800edd 320 SUPERFAMILY SSF52151 200 318 7.59E-78 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 GBCGDNIH2_RS11470 2a9effac405d128392af8789d6800edd 320 SUPERFAMILY SSF52151 4 126 7.59E-78 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 GBCGDNIH2_RS11470 2a9effac405d128392af8789d6800edd 320 PIRSF PIRSF000446 1 320 9.3E-93 T 29-03-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 GBCGDNIH2_RS11470 2a9effac405d128392af8789d6800edd 320 Gene3D G3DSA:3.40.366.10 192 320 1.3E-31 T 29-03-2018 GBCGDNIH2_RS11470 2a9effac405d128392af8789d6800edd 320 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 5 301 1.0E-96 T 29-03-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 GBCGDNIH2_RS11470 2a9effac405d128392af8789d6800edd 320 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7 312 2.7E-42 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain GBCGDNIH2_RS11470 2a9effac405d128392af8789d6800edd 320 Gene3D G3DSA:3.40.366.10 2 191 1.7E-48 T 29-03-2018 GBCGDNIH2_RS06250 f444af9fc3aaccb1b8182f56ef818638 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 4.2E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS06250 f444af9fc3aaccb1b8182f56ef818638 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 2.4E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS06250 f444af9fc3aaccb1b8182f56ef818638 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 2.4E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS06250 f444af9fc3aaccb1b8182f56ef818638 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 2.4E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS06250 f444af9fc3aaccb1b8182f56ef818638 310 Pfam PF03466 LysR substrate binding domain 89 291 1.3E-36 T 29-03-2018 IPR005119 LysR, substrate-binding GBCGDNIH2_RS06250 f444af9fc3aaccb1b8182f56ef818638 310 SUPERFAMILY SSF46785 6 110 2.95E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS06250 f444af9fc3aaccb1b8182f56ef818638 310 Gene3D G3DSA:1.10.10.10 3 87 1.3E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS06250 f444af9fc3aaccb1b8182f56ef818638 310 Gene3D G3DSA:3.40.190.10 176 263 2.9E-15 T 29-03-2018 GBCGDNIH2_RS06250 f444af9fc3aaccb1b8182f56ef818638 310 Gene3D G3DSA:3.40.190.10 91 175 5.5E-17 T 29-03-2018 GBCGDNIH2_RS06250 f444af9fc3aaccb1b8182f56ef818638 310 SUPERFAMILY SSF53850 89 296 4.71E-38 T 29-03-2018 GBCGDNIH2_RS05320 59c291e59e644c6228f2d18faa559f79 319 Hamap MF_00524 Glucokinase [glk]. 6 319 30.331 T 29-03-2018 IPR003836 Glucokinase GO:0004340|GO:0005524|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 GBCGDNIH2_RS05320 59c291e59e644c6228f2d18faa559f79 319 SUPERFAMILY SSF53067 10 315 1.77E-52 T 29-03-2018 GBCGDNIH2_RS05320 59c291e59e644c6228f2d18faa559f79 319 Gene3D G3DSA:3.40.367.20 111 303 1.3E-29 T 29-03-2018 GBCGDNIH2_RS05320 59c291e59e644c6228f2d18faa559f79 319 Gene3D G3DSA:3.30.420.40 3 110 9.2E-16 T 29-03-2018 GBCGDNIH2_RS05320 59c291e59e644c6228f2d18faa559f79 319 Pfam PF02685 Glucokinase 8 316 1.1E-90 T 29-03-2018 IPR003836 Glucokinase GO:0004340|GO:0005524|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 GBCGDNIH2_RS05320 59c291e59e644c6228f2d18faa559f79 319 TIGRFAM TIGR00749 glk: glucokinase 8 313 2.1E-74 T 29-03-2018 IPR003836 Glucokinase GO:0004340|GO:0005524|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 GBCGDNIH2_RS00980 7ccd559dcbecf1bb2573b9104d3bb204 460 Gene3D G3DSA:2.40.50.100 70 332 2.8E-12 T 29-03-2018 GBCGDNIH2_RS00980 7ccd559dcbecf1bb2573b9104d3bb204 460 SUPERFAMILY SSF111369 78 151 2.09E-6 T 29-03-2018 GBCGDNIH2_RS00980 7ccd559dcbecf1bb2573b9104d3bb204 460 Pfam PF13437 HlyD family secretion protein 296 380 5.2E-10 T 29-03-2018 GBCGDNIH2_RS00980 7ccd559dcbecf1bb2573b9104d3bb204 460 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 308 329 5.9E-22 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 GBCGDNIH2_RS00980 7ccd559dcbecf1bb2573b9104d3bb204 460 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 424 439 5.9E-22 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 GBCGDNIH2_RS00980 7ccd559dcbecf1bb2573b9104d3bb204 460 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 439 459 5.9E-22 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 GBCGDNIH2_RS00980 7ccd559dcbecf1bb2573b9104d3bb204 460 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 44 67 5.9E-22 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 GBCGDNIH2_RS00980 7ccd559dcbecf1bb2573b9104d3bb204 460 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 86 106 5.9E-22 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 GBCGDNIH2_RS00980 7ccd559dcbecf1bb2573b9104d3bb204 460 Pfam PF13533 Biotin-lipoyl like 83 109 1.0E-6 T 29-03-2018 GBCGDNIH2_RS00980 7ccd559dcbecf1bb2573b9104d3bb204 460 TIGRFAM TIGR01843 type_I_hlyD: type I secretion membrane fusion protein, HlyD family 35 459 7.1E-107 T 29-03-2018 IPR010129 Type I secretion membrane fusion protein, HlyD family GO:0015031|GO:0016021 GBCGDNIH2_RS03690 7eec31ba2bf6a51f706413e6ccd121b4 159 SMART SM00344 11 120 4.8E-42 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 GBCGDNIH2_RS03690 7eec31ba2bf6a51f706413e6ccd121b4 159 Gene3D G3DSA:1.10.10.10 6 62 2.6E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS03690 7eec31ba2bf6a51f706413e6ccd121b4 159 Pfam PF01037 Lrp/AsnC ligand binding domain 79 146 3.0E-14 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain GBCGDNIH2_RS03690 7eec31ba2bf6a51f706413e6ccd121b4 159 Pfam PF13412 Winged helix-turn-helix DNA-binding 11 58 1.2E-20 T 29-03-2018 GBCGDNIH2_RS03690 7eec31ba2bf6a51f706413e6ccd121b4 159 SUPERFAMILY SSF46785 10 71 4.58E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS03690 7eec31ba2bf6a51f706413e6ccd121b4 159 SUPERFAMILY SSF54909 75 157 1.74E-13 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel GBCGDNIH2_RS03690 7eec31ba2bf6a51f706413e6ccd121b4 159 Gene3D G3DSA:3.30.70.920 63 146 5.6E-17 T 29-03-2018 GBCGDNIH2_RS03690 7eec31ba2bf6a51f706413e6ccd121b4 159 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 27 38 3.4E-18 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 GBCGDNIH2_RS03690 7eec31ba2bf6a51f706413e6ccd121b4 159 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 38 57 3.4E-18 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 GBCGDNIH2_RS03690 7eec31ba2bf6a51f706413e6ccd121b4 159 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 11 27 3.4E-18 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 GBCGDNIH2_RS03140 cdce189cc24bd9b858cfa555638dc52a 683 Gene3D G3DSA:2.150.10.10 521 683 4.4E-12 T 29-03-2018 GBCGDNIH2_RS03140 cdce189cc24bd9b858cfa555638dc52a 683 SUPERFAMILY SSF51120 523 675 6.54E-13 T 29-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal GBCGDNIH2_RS03140 cdce189cc24bd9b858cfa555638dc52a 683 Gene3D G3DSA:3.90.1720.10 8 233 1.9E-4 T 29-03-2018 GBCGDNIH2_RS09910 6ca8a59c514d4098edbf988b2e8c1279 308 SUPERFAMILY SSF161098 35 288 2.9E-49 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GBCGDNIH2_RS09910 6ca8a59c514d4098edbf988b2e8c1279 308 TIGRFAM TIGR02139 permease_CysT: sulfate ABC transporter, permease protein CysT 31 291 5.5E-104 T 29-03-2018 IPR011865 Sulphate ABC transporter, permease protein CysT GO:0008272|GO:0015116|GO:0016021 GBCGDNIH2_RS09910 6ca8a59c514d4098edbf988b2e8c1279 308 Gene3D G3DSA:1.10.3720.10 34 297 1.0E-38 T 29-03-2018 GBCGDNIH2_RS09910 6ca8a59c514d4098edbf988b2e8c1279 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 290 5.6E-21 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GBCGDNIH2_RS09910 6ca8a59c514d4098edbf988b2e8c1279 308 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 32 290 1.0E-86 T 29-03-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 GBCGDNIH2_RS06805 6359b24580f7de7350ead6c244be9290 358 Pfam PF09084 NMT1/THI5 like 82 288 6.0E-18 T 29-03-2018 IPR015168 SsuA/THI5-like GBCGDNIH2_RS06805 6359b24580f7de7350ead6c244be9290 358 Gene3D G3DSA:3.40.190.10 176 357 7.4E-25 T 29-03-2018 GBCGDNIH2_RS06805 6359b24580f7de7350ead6c244be9290 358 Gene3D G3DSA:3.40.190.10 61 175 4.1E-13 T 29-03-2018 GBCGDNIH2_RS06805 6359b24580f7de7350ead6c244be9290 358 SUPERFAMILY SSF53850 82 347 8.39E-37 T 29-03-2018 GBCGDNIH2_RS06705 05322fac398691589ee2df08d6a73a72 496 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 357 464 9.7E-27 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 GBCGDNIH2_RS06705 05322fac398691589ee2df08d6a73a72 496 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 16 337 6.0E-48 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS06705 05322fac398691589ee2df08d6a73a72 496 Gene3D G3DSA:3.50.50.60 13 166 7.4E-20 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS06705 05322fac398691589ee2df08d6a73a72 496 Gene3D G3DSA:3.50.50.60 167 287 1.8E-19 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS06705 05322fac398691589ee2df08d6a73a72 496 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 302 324 2.0E-26 T 29-03-2018 GBCGDNIH2_RS06705 05322fac398691589ee2df08d6a73a72 496 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 18 37 2.0E-26 T 29-03-2018 GBCGDNIH2_RS06705 05322fac398691589ee2df08d6a73a72 496 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 188 206 2.0E-26 T 29-03-2018 GBCGDNIH2_RS06705 05322fac398691589ee2df08d6a73a72 496 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 149 167 2.0E-26 T 29-03-2018 GBCGDNIH2_RS06705 05322fac398691589ee2df08d6a73a72 496 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 272 288 2.0E-26 T 29-03-2018 GBCGDNIH2_RS06705 05322fac398691589ee2df08d6a73a72 496 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 50 65 5.0E-50 T 29-03-2018 GBCGDNIH2_RS06705 05322fac398691589ee2df08d6a73a72 496 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 273 287 5.0E-50 T 29-03-2018 GBCGDNIH2_RS06705 05322fac398691589ee2df08d6a73a72 496 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 417 432 5.0E-50 T 29-03-2018 GBCGDNIH2_RS06705 05322fac398691589ee2df08d6a73a72 496 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 17 39 5.0E-50 T 29-03-2018 GBCGDNIH2_RS06705 05322fac398691589ee2df08d6a73a72 496 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 439 459 5.0E-50 T 29-03-2018 GBCGDNIH2_RS06705 05322fac398691589ee2df08d6a73a72 496 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 188 213 5.0E-50 T 29-03-2018 GBCGDNIH2_RS06705 05322fac398691589ee2df08d6a73a72 496 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 317 324 5.0E-50 T 29-03-2018 GBCGDNIH2_RS06705 05322fac398691589ee2df08d6a73a72 496 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 152 161 5.0E-50 T 29-03-2018 GBCGDNIH2_RS06705 05322fac398691589ee2df08d6a73a72 496 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 352 373 5.0E-50 T 29-03-2018 GBCGDNIH2_RS06705 05322fac398691589ee2df08d6a73a72 496 SUPERFAMILY SSF55424 354 473 6.87E-33 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 GBCGDNIH2_RS06705 05322fac398691589ee2df08d6a73a72 496 Gene3D G3DSA:3.50.50.60 288 368 9.0E-12 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS06705 05322fac398691589ee2df08d6a73a72 496 SUPERFAMILY SSF51905 9 346 9.5E-55 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS06705 05322fac398691589ee2df08d6a73a72 496 PIRSF PIRSF000350 2 471 7.1E-62 T 29-03-2018 GBCGDNIH2_RS06705 05322fac398691589ee2df08d6a73a72 496 Gene3D G3DSA:3.30.390.30 369 478 5.0E-30 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 GBCGDNIH2_RS11585 3dd124d20030ee8811c1cee3295d0733 196 SUPERFAMILY SSF56235 17 191 4.27E-58 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal GBCGDNIH2_RS11585 3dd124d20030ee8811c1cee3295d0733 196 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 20 191 5.9E-83 T 29-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 GBCGDNIH2_RS11585 3dd124d20030ee8811c1cee3295d0733 196 PIRSF PIRSF039093 14 194 8.2E-83 T 29-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 GBCGDNIH2_RS11585 3dd124d20030ee8811c1cee3295d0733 196 Gene3D G3DSA:3.60.20.10 20 193 1.2E-34 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal GBCGDNIH2_RS11585 3dd124d20030ee8811c1cee3295d0733 196 Pfam PF00227 Proteasome subunit 18 190 1.0E-23 T 29-03-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 GBCGDNIH2_RS11585 3dd124d20030ee8811c1cee3295d0733 196 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 19 191 40.34 T 29-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 GBCGDNIH2_RS04635 6ef1f60c6f6caa0ba9b4f07e41acdaec 531 Pfam PF04679 ATP dependent DNA ligase C terminal region 421 515 3.3E-10 T 29-03-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 GBCGDNIH2_RS04635 6ef1f60c6f6caa0ba9b4f07e41acdaec 531 SUPERFAMILY SSF50249 405 530 2.06E-31 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold GBCGDNIH2_RS04635 6ef1f60c6f6caa0ba9b4f07e41acdaec 531 Gene3D G3DSA:2.40.50.140 403 531 3.5E-26 T 29-03-2018 GBCGDNIH2_RS04635 6ef1f60c6f6caa0ba9b4f07e41acdaec 531 TIGRFAM TIGR04120 DNA_lig_bact: DNA ligase, ATP-dependent, PP_1105 family 3 530 8.4E-247 T 29-03-2018 IPR026333 ATP-dependent DNA ligase, PP_1105 family GBCGDNIH2_RS04635 6ef1f60c6f6caa0ba9b4f07e41acdaec 531 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 228 236 - T 29-03-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 GBCGDNIH2_RS04635 6ef1f60c6f6caa0ba9b4f07e41acdaec 531 Pfam PF01068 ATP dependent DNA ligase domain 206 400 6.8E-29 T 29-03-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 GBCGDNIH2_RS04635 6ef1f60c6f6caa0ba9b4f07e41acdaec 531 SUPERFAMILY SSF56091 203 400 1.87E-48 T 29-03-2018 GBCGDNIH2_RS04635 6ef1f60c6f6caa0ba9b4f07e41acdaec 531 Gene3D G3DSA:3.30.470.30 190 339 2.0E-26 T 29-03-2018 GBCGDNIH2_RS04635 6ef1f60c6f6caa0ba9b4f07e41acdaec 531 Gene3D G3DSA:3.30.1490.70 340 400 1.0E-15 T 29-03-2018 GBCGDNIH2_RS05960 3b04ee0616af5101598e5520be8f751e 151 PIRSF PIRSF003230 1 140 1.0E-44 T 29-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 GBCGDNIH2_RS05960 3b04ee0616af5101598e5520be8f751e 151 Gene3D G3DSA:3.10.129.10 3 145 7.6E-39 T 29-03-2018 GBCGDNIH2_RS05960 3b04ee0616af5101598e5520be8f751e 151 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 10 125 8.4E-31 T 29-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 GBCGDNIH2_RS05960 3b04ee0616af5101598e5520be8f751e 151 Pfam PF03061 Thioesterase superfamily 21 104 4.7E-18 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 GBCGDNIH2_RS05960 3b04ee0616af5101598e5520be8f751e 151 TIGRFAM TIGR02799 thio_ybgC: tol-pal system-associated acyl-CoA thioesterase 7 132 7.0E-46 T 29-03-2018 IPR014166 Tol-Pal system-associated acyl-CoA thioesterase GO:0016790 GBCGDNIH2_RS05960 3b04ee0616af5101598e5520be8f751e 151 ProSitePatterns PS01328 4-hydroxybenzoyl-CoA thioesterase family active site. 12 29 - T 29-03-2018 IPR008272 4-hydroxybenzoyl-CoA thioesterase, active site GO:0016787 GBCGDNIH2_RS05960 3b04ee0616af5101598e5520be8f751e 151 SUPERFAMILY SSF54637 2 136 3.74E-40 T 29-03-2018 IPR029069 HotDog domain GBCGDNIH2_RS06145 56c85be4446144ea31c8441d006cb26b 332 PRINTS PR01713 Nucleotide sugar epimerase signature 290 307 4.1E-5 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 GBCGDNIH2_RS06145 56c85be4446144ea31c8441d006cb26b 332 PRINTS PR01713 Nucleotide sugar epimerase signature 247 262 4.1E-5 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 GBCGDNIH2_RS06145 56c85be4446144ea31c8441d006cb26b 332 PRINTS PR01713 Nucleotide sugar epimerase signature 224 239 4.1E-5 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 GBCGDNIH2_RS06145 56c85be4446144ea31c8441d006cb26b 332 Gene3D G3DSA:3.40.50.720 5 199 1.3E-25 T 29-03-2018 GBCGDNIH2_RS06145 56c85be4446144ea31c8441d006cb26b 332 Pfam PF01370 NAD dependent epimerase/dehydratase family 17 253 2.0E-39 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 GBCGDNIH2_RS06145 56c85be4446144ea31c8441d006cb26b 332 SUPERFAMILY SSF51735 10 327 3.08E-71 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS06145 56c85be4446144ea31c8441d006cb26b 332 Gene3D G3DSA:3.90.25.10 200 331 2.3E-28 T 29-03-2018 GBCGDNIH2_RS04940 6291aa05fa650c36f789d55416cb6596 212 SUPERFAMILY SSF52833 3 208 1.78E-68 T 29-03-2018 IPR012336 Thioredoxin-like fold GBCGDNIH2_RS04940 6291aa05fa650c36f789d55416cb6596 212 PIRSF PIRSF000239 1 208 8.6E-78 T 29-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 GBCGDNIH2_RS04940 6291aa05fa650c36f789d55416cb6596 212 Gene3D G3DSA:3.40.30.10 1 151 1.1E-38 T 29-03-2018 GBCGDNIH2_RS04940 6291aa05fa650c36f789d55416cb6596 212 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 156 195 1.3E-12 T 29-03-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 GBCGDNIH2_RS04940 6291aa05fa650c36f789d55416cb6596 212 Pfam PF00578 AhpC/TSA family 6 134 6.6E-31 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 GBCGDNIH2_RS04940 6291aa05fa650c36f789d55416cb6596 212 Gene3D G3DSA:3.30.1020.10 152 212 9.2E-24 T 29-03-2018 GBCGDNIH2_RS10480 a22469db203ae9989079c00a306e1bbc 976 Gene3D G3DSA:3.90.320.10 669 891 4.4E-11 T 29-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 GBCGDNIH2_RS10480 a22469db203ae9989079c00a306e1bbc 976 TIGRFAM TIGR02786 addB_alphas: double-strand break repair protein AddB 2 970 1.4E-271 T 29-03-2018 IPR014153 Double-strand break repair protein AddB GBCGDNIH2_RS10480 a22469db203ae9989079c00a306e1bbc 976 Pfam PF12705 PD-(D/E)XK nuclease superfamily 704 945 7.5E-24 T 29-03-2018 GBCGDNIH2_RS10480 a22469db203ae9989079c00a306e1bbc 976 Gene3D G3DSA:3.40.50.300 287 668 3.3E-5 T 29-03-2018 GBCGDNIH2_RS10480 a22469db203ae9989079c00a306e1bbc 976 SUPERFAMILY SSF52540 303 699 2.55E-33 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS07425 b267eb3d4fe814422ea3056ba75ce674 176 Pfam PF06793 Uncharacterised protein family (UPF0262) 16 175 4.7E-63 T 29-03-2018 IPR008321 Uncharacterised conserved protein UCP032146 GBCGDNIH2_RS07425 b267eb3d4fe814422ea3056ba75ce674 176 Hamap MF_00678 UPF0262 protein . 15 175 37.257 T 29-03-2018 IPR008321 Uncharacterised conserved protein UCP032146 GBCGDNIH2_RS06620 4395c10c08d28d284b51060539d3dc09 131 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 123 4.4E-11 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain GBCGDNIH2_RS06620 4395c10c08d28d284b51060539d3dc09 131 SUPERFAMILY SSF54593 3 128 6.85E-29 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase GBCGDNIH2_RS06620 4395c10c08d28d284b51060539d3dc09 131 Gene3D G3DSA:3.10.180.10 1 130 1.5E-28 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase GBCGDNIH2_RS04720 b86ed5dafefeffb4e9322379a8823f0a 354 SMART SM00530 9 65 5.9E-7 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 GBCGDNIH2_RS04720 b86ed5dafefeffb4e9322379a8823f0a 354 Pfam PF01381 Helix-turn-helix 13 63 2.7E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 GBCGDNIH2_RS04720 b86ed5dafefeffb4e9322379a8823f0a 354 Gene3D G3DSA:1.10.3100.10 1 128 3.5E-12 T 29-03-2018 IPR027910 YdiL-like domain GBCGDNIH2_RS04720 b86ed5dafefeffb4e9322379a8823f0a 354 Pfam PF06114 IrrE N-terminal-like domain 158 266 1.5E-15 T 29-03-2018 IPR010359 IrrE N-terminal-like domain GBCGDNIH2_RS04720 b86ed5dafefeffb4e9322379a8823f0a 354 SUPERFAMILY SSF47413 6 65 5.35E-11 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GBCGDNIH2_RS05340 8e2e6552a219b9d9e572a6bf94a26d95 522 SUPERFAMILY SSF81296 422 522 6.3E-24 T 29-03-2018 IPR014756 Immunoglobulin E-set GBCGDNIH2_RS05340 8e2e6552a219b9d9e572a6bf94a26d95 522 SUPERFAMILY SSF74650 51 420 4.08E-152 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 GBCGDNIH2_RS05340 8e2e6552a219b9d9e572a6bf94a26d95 522 PIRSF PIRSF006281 3 522 1.4E-187 T 29-03-2018 IPR014438 Glucan biosynthesis, periplasmic, MdoG/D GBCGDNIH2_RS05340 8e2e6552a219b9d9e572a6bf94a26d95 522 Gene3D G3DSA:2.60.40.10 422 522 5.3E-25 T 29-03-2018 IPR013783 Immunoglobulin-like fold GBCGDNIH2_RS05340 8e2e6552a219b9d9e572a6bf94a26d95 522 Pfam PF04349 Periplasmic glucan biosynthesis protein, MdoG 51 520 2.1E-194 T 29-03-2018 IPR007444 Glucan biosynthesis, periplasmic, MdoG C-terminal GO:0016051|GO:0042597 GBCGDNIH2_RS05340 8e2e6552a219b9d9e572a6bf94a26d95 522 Gene3D G3DSA:2.70.98.10 51 418 1.3E-158 T 29-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 GBCGDNIH2_RS00805 a765f1b6e2eff6742d8127203d1e1a8d 293 SMART SM00898 2 124 4.1E-44 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 GBCGDNIH2_RS00805 a765f1b6e2eff6742d8127203d1e1a8d 293 Gene3D G3DSA:3.20.190.10 2 141 5.8E-39 T 29-03-2018 GBCGDNIH2_RS00805 a765f1b6e2eff6742d8127203d1e1a8d 293 SUPERFAMILY SSF81624 2 149 3.66E-37 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 GBCGDNIH2_RS00805 a765f1b6e2eff6742d8127203d1e1a8d 293 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 286 40.84 T 29-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 GBCGDNIH2_RS00805 a765f1b6e2eff6742d8127203d1e1a8d 293 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 140 229 6.8E-25 T 29-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 GBCGDNIH2_RS00805 a765f1b6e2eff6742d8127203d1e1a8d 293 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 285 1.4E-80 T 29-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 GBCGDNIH2_RS00805 a765f1b6e2eff6742d8127203d1e1a8d 293 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 123 1.0E-32 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 GBCGDNIH2_RS00805 a765f1b6e2eff6742d8127203d1e1a8d 293 SUPERFAMILY SSF46946 141 233 7.59E-29 T 29-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 GBCGDNIH2_RS00805 a765f1b6e2eff6742d8127203d1e1a8d 293 SMART SM01232 140 232 2.2E-47 T 29-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 GBCGDNIH2_RS00805 a765f1b6e2eff6742d8127203d1e1a8d 293 SUPERFAMILY SSF57716 228 286 2.37E-12 T 29-03-2018 GBCGDNIH2_RS00805 a765f1b6e2eff6742d8127203d1e1a8d 293 Gene3D G3DSA:1.10.8.50 142 292 7.5E-48 T 29-03-2018 GBCGDNIH2_RS06645 c7b2140c91167c4febfaf1942029da16 341 Gene3D G3DSA:3.90.550.10 33 332 6.9E-7 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS06645 c7b2140c91167c4febfaf1942029da16 341 Pfam PF04488 Glycosyltransferase sugar-binding region containing DXD motif 91 140 5.1E-8 T 29-03-2018 IPR007577 Glycosyltransferase, DXD sugar-binding motif GBCGDNIH2_RS06645 c7b2140c91167c4febfaf1942029da16 341 SUPERFAMILY SSF53448 13 298 8.06E-42 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS00795 504c85e57cc5fccc6c086b8c10f4ba84 420 SUPERFAMILY SSF102645 205 418 2.49E-68 T 29-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 GBCGDNIH2_RS00795 504c85e57cc5fccc6c086b8c10f4ba84 420 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 11 411 8.3E-113 T 29-03-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 GBCGDNIH2_RS00795 504c85e57cc5fccc6c086b8c10f4ba84 420 Gene3D G3DSA:3.40.50.1950 6 195 4.7E-51 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 GBCGDNIH2_RS00795 504c85e57cc5fccc6c086b8c10f4ba84 420 Gene3D G3DSA:3.40.50.10300 198 420 8.0E-60 T 29-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 GBCGDNIH2_RS00795 504c85e57cc5fccc6c086b8c10f4ba84 420 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 207 389 2.5E-61 T 29-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 GBCGDNIH2_RS00795 504c85e57cc5fccc6c086b8c10f4ba84 420 Pfam PF02441 Flavoprotein 13 185 4.1E-40 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 GBCGDNIH2_RS00795 504c85e57cc5fccc6c086b8c10f4ba84 420 SUPERFAMILY SSF52507 9 186 1.96E-54 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 GBCGDNIH2_RS03270 1fcc7462b3b4d002b0fb90b77f67efb5 281 Gene3D G3DSA:3.90.1170.20 2 138 4.9E-43 T 29-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 GBCGDNIH2_RS03270 1fcc7462b3b4d002b0fb90b77f67efb5 281 PIRSF PIRSF006250 6 281 2.7E-93 T 29-03-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 GBCGDNIH2_RS03270 1fcc7462b3b4d002b0fb90b77f67efb5 281 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 113 278 2.0E-58 T 29-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 GBCGDNIH2_RS03270 1fcc7462b3b4d002b0fb90b77f67efb5 281 Gene3D G3DSA:3.20.20.70 139 269 1.5E-39 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS03270 1fcc7462b3b4d002b0fb90b77f67efb5 281 SUPERFAMILY SSF54675 4 112 1.02E-32 T 29-03-2018 GBCGDNIH2_RS03270 1fcc7462b3b4d002b0fb90b77f67efb5 281 SUPERFAMILY SSF51690 113 279 2.83E-57 T 29-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 GBCGDNIH2_RS03270 1fcc7462b3b4d002b0fb90b77f67efb5 281 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 24 111 1.2E-25 T 29-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 GBCGDNIH2_RS03270 1fcc7462b3b4d002b0fb90b77f67efb5 281 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 13 279 2.7E-98 T 29-03-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 GBCGDNIH2_RS07410 52c8579ec38acee0ae9938e5e1b0be09 356 Pfam PF00534 Glycosyl transferases group 1 177 330 4.2E-15 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 GBCGDNIH2_RS07410 52c8579ec38acee0ae9938e5e1b0be09 356 Gene3D G3DSA:3.40.50.2000 133 333 9.9E-21 T 29-03-2018 GBCGDNIH2_RS07410 52c8579ec38acee0ae9938e5e1b0be09 356 SUPERFAMILY SSF53756 9 349 4.29E-35 T 29-03-2018 GBCGDNIH2_RS07005 71393bf595f8bc72d5c964594093ea93 94 SMART SM00411 1 87 2.2E-28 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 GBCGDNIH2_RS07005 71393bf595f8bc72d5c964594093ea93 94 Pfam PF00216 Bacterial DNA-binding protein 2 87 1.9E-28 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 GBCGDNIH2_RS07005 71393bf595f8bc72d5c964594093ea93 94 SUPERFAMILY SSF47729 2 90 6.04E-27 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 GBCGDNIH2_RS07005 71393bf595f8bc72d5c964594093ea93 94 Gene3D G3DSA:4.10.520.10 1 94 6.0E-29 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 GBCGDNIH2_RS07005 71393bf595f8bc72d5c964594093ea93 94 PRINTS PR01727 Prokaryotic integration host factor signature 37 52 7.6E-15 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 GBCGDNIH2_RS07005 71393bf595f8bc72d5c964594093ea93 94 PRINTS PR01727 Prokaryotic integration host factor signature 71 85 7.6E-15 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 GBCGDNIH2_RS07005 71393bf595f8bc72d5c964594093ea93 94 PRINTS PR01727 Prokaryotic integration host factor signature 55 68 7.6E-15 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 GBCGDNIH2_RS07005 71393bf595f8bc72d5c964594093ea93 94 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 43 62 - T 29-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 GBCGDNIH2_RS03280 356eaa419403724f8cb4a5aeb114ce48 435 TIGRFAM TIGR04022 sulfur_SfnB: sulfur acquisition oxidoreductase, SfnB family 43 434 6.3E-185 T 29-03-2018 IPR023922 Sulphate-starvation-induced SfnB GBCGDNIH2_RS03280 356eaa419403724f8cb4a5aeb114ce48 435 SUPERFAMILY SSF47203 273 434 1.77E-23 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 GBCGDNIH2_RS03280 356eaa419403724f8cb4a5aeb114ce48 435 PIRSF PIRSF016578 37 427 1.9E-31 T 29-03-2018 GBCGDNIH2_RS03280 356eaa419403724f8cb4a5aeb114ce48 435 Gene3D G3DSA:1.20.140.10 266 435 3.8E-19 T 29-03-2018 GBCGDNIH2_RS03280 356eaa419403724f8cb4a5aeb114ce48 435 Gene3D G3DSA:1.10.540.10 44 157 3.2E-15 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 GBCGDNIH2_RS03280 356eaa419403724f8cb4a5aeb114ce48 435 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 54 146 1.0E-10 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 GBCGDNIH2_RS03280 356eaa419403724f8cb4a5aeb114ce48 435 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 278 410 2.8E-24 T 29-03-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain GBCGDNIH2_RS03280 356eaa419403724f8cb4a5aeb114ce48 435 Gene3D G3DSA:2.40.110.10 158 259 2.2E-15 T 29-03-2018 GBCGDNIH2_RS03280 356eaa419403724f8cb4a5aeb114ce48 435 SUPERFAMILY SSF56645 54 258 1.7E-44 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 GBCGDNIH2_RS08915 82ce778c90b8303f0ec6643d0a2ebe13 235 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 4 225 1.9E-43 T 29-03-2018 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 GBCGDNIH2_RS08915 82ce778c90b8303f0ec6643d0a2ebe13 235 TIGRFAM TIGR01868 casD_Cas5e: CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI 3 199 7.1E-47 T 29-03-2018 IPR010147 CRISPR-associated protein, CasD GO:0003723|GO:0051607 GBCGDNIH2_RS08915 82ce778c90b8303f0ec6643d0a2ebe13 235 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 4 46 2.6E-7 T 29-03-2018 IPR013422 CRISPR-associated protein Cas5, N-terminal GBCGDNIH2_RS05405 9f31380851e9c68d49a166025ccde6f4 298 Gene3D G3DSA:3.40.50.1820 27 296 2.0E-40 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS05405 9f31380851e9c68d49a166025ccde6f4 298 SUPERFAMILY SSF53474 31 295 6.46E-39 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS05405 9f31380851e9c68d49a166025ccde6f4 298 Pfam PF12697 Alpha/beta hydrolase family 50 286 1.3E-19 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 GBCGDNIH2_RS05405 9f31380851e9c68d49a166025ccde6f4 298 PRINTS PR00111 Alpha/beta hydrolase fold signature 244 258 6.2E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 GBCGDNIH2_RS05405 9f31380851e9c68d49a166025ccde6f4 298 PRINTS PR00111 Alpha/beta hydrolase fold signature 73 88 6.2E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 GBCGDNIH2_RS05405 9f31380851e9c68d49a166025ccde6f4 298 PRINTS PR00111 Alpha/beta hydrolase fold signature 118 131 6.2E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 GBCGDNIH2_RS07895 3f64246e2a4772d13a0f66f0069c701f 319 Gene3D G3DSA:1.10.3470.10 2 292 1.9E-36 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like GBCGDNIH2_RS07895 3f64246e2a4772d13a0f66f0069c701f 319 Pfam PF02653 Branched-chain amino acid transport system / permease component 9 287 1.2E-38 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS01305 a18e501c26a31762576e5dd00d14efe3 358 Gene3D G3DSA:3.40.190.10 174 357 7.2E-29 T 29-03-2018 GBCGDNIH2_RS01305 a18e501c26a31762576e5dd00d14efe3 358 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 72 353 2.9E-68 T 29-03-2018 IPR010067 Aliphatic sulfonates-binding protein GO:0016020|GO:0042626 GBCGDNIH2_RS01305 a18e501c26a31762576e5dd00d14efe3 358 Gene3D G3DSA:3.40.190.10 66 173 1.6E-16 T 29-03-2018 GBCGDNIH2_RS01305 a18e501c26a31762576e5dd00d14efe3 358 Pfam PF13379 NMT1-like family 68 291 7.4E-12 T 29-03-2018 GBCGDNIH2_RS01305 a18e501c26a31762576e5dd00d14efe3 358 SMART SM00062 71 287 3.1E-12 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF GBCGDNIH2_RS01305 a18e501c26a31762576e5dd00d14efe3 358 SUPERFAMILY SSF53850 69 292 9.64E-44 T 29-03-2018 GBCGDNIH2_RS08975 c9caaf0f800184f33e6c0a531fcb35f6 150 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 34 140 23.607 T 29-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS GBCGDNIH2_RS08975 c9caaf0f800184f33e6c0a531fcb35f6 150 SUPERFAMILY SSF81301 42 140 1.8E-31 T 29-03-2018 GBCGDNIH2_RS08975 c9caaf0f800184f33e6c0a531fcb35f6 150 Pfam PF02410 Ribosomal silencing factor during starvation 45 139 9.6E-25 T 29-03-2018 GBCGDNIH2_RS08975 c9caaf0f800184f33e6c0a531fcb35f6 150 Gene3D G3DSA:3.30.460.10 37 150 1.3E-30 T 29-03-2018 GBCGDNIH2_RS08975 c9caaf0f800184f33e6c0a531fcb35f6 150 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 43 139 2.3E-31 T 29-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS GBCGDNIH2_RS02220 14f95826f01dfa31c5ce566fdbf8e197 462 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 12 457 30.215 T 29-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GBCGDNIH2_RS02220 14f95826f01dfa31c5ce566fdbf8e197 462 SUPERFAMILY SSF51984 10 96 4.32E-11 T 29-03-2018 GBCGDNIH2_RS02220 14f95826f01dfa31c5ce566fdbf8e197 462 Gene3D G3DSA:3.40.1190.10 98 318 6.8E-49 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 GBCGDNIH2_RS02220 14f95826f01dfa31c5ce566fdbf8e197 462 Gene3D G3DSA:3.90.190.20 323 456 8.9E-33 T 29-03-2018 GBCGDNIH2_RS02220 14f95826f01dfa31c5ce566fdbf8e197 462 SUPERFAMILY SSF53623 112 316 2.22E-47 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 GBCGDNIH2_RS02220 14f95826f01dfa31c5ce566fdbf8e197 462 SUPERFAMILY SSF53244 318 456 1.92E-37 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 GBCGDNIH2_RS02220 14f95826f01dfa31c5ce566fdbf8e197 462 Pfam PF08245 Mur ligase middle domain 118 298 5.3E-30 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 GBCGDNIH2_RS02220 14f95826f01dfa31c5ce566fdbf8e197 462 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 116 139 - T 29-03-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 GBCGDNIH2_RS02220 14f95826f01dfa31c5ce566fdbf8e197 462 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 15 455 2.3E-105 T 29-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GBCGDNIH2_RS02220 14f95826f01dfa31c5ce566fdbf8e197 462 Gene3D G3DSA:3.40.50.720 4 97 1.3E-11 T 29-03-2018 GBCGDNIH2_RS11640 cacb60c0ae63f18b20523caa5dffaa7c 356 SUPERFAMILY SSF53756 2 337 3.02E-63 T 29-03-2018 GBCGDNIH2_RS11640 cacb60c0ae63f18b20523caa5dffaa7c 356 Pfam PF13439 Glycosyltransferase Family 4 14 165 6.9E-16 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 GBCGDNIH2_RS11640 cacb60c0ae63f18b20523caa5dffaa7c 356 Gene3D G3DSA:3.40.50.2000 1 171 5.4E-11 T 29-03-2018 GBCGDNIH2_RS11640 cacb60c0ae63f18b20523caa5dffaa7c 356 Pfam PF13692 Glycosyl transferases group 1 182 311 6.1E-17 T 29-03-2018 GBCGDNIH2_RS11640 cacb60c0ae63f18b20523caa5dffaa7c 356 Gene3D G3DSA:3.40.50.2000 172 325 3.9E-28 T 29-03-2018 GBCGDNIH2_RS04490 f5b342fd2ca06b9a5beee7bb6f5f08d3 265 Gene3D G3DSA:3.40.50.300 13 265 1.3E-68 T 29-03-2018 GBCGDNIH2_RS04490 f5b342fd2ca06b9a5beee7bb6f5f08d3 265 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GBCGDNIH2_RS04490 f5b342fd2ca06b9a5beee7bb6f5f08d3 265 SUPERFAMILY SSF52540 16 260 1.22E-74 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS04490 f5b342fd2ca06b9a5beee7bb6f5f08d3 265 SMART SM00382 41 238 3.4E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS04490 f5b342fd2ca06b9a5beee7bb6f5f08d3 265 Pfam PF00005 ABC transporter 32 190 7.0E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GBCGDNIH2_RS04490 f5b342fd2ca06b9a5beee7bb6f5f08d3 265 PIRSF PIRSF039085 13 265 3.8E-106 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 GBCGDNIH2_RS10135 644e119e1f26960f0a8677bc794788ae 375 SUPERFAMILY SSF52402 1 243 2.65E-45 T 29-03-2018 GBCGDNIH2_RS10135 644e119e1f26960f0a8677bc794788ae 375 Gene3D G3DSA:3.40.50.620 1 210 3.4E-52 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GBCGDNIH2_RS10135 644e119e1f26960f0a8677bc794788ae 375 Gene3D G3DSA:2.40.30.10 278 361 4.2E-19 T 29-03-2018 GBCGDNIH2_RS10135 644e119e1f26960f0a8677bc794788ae 375 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 1 352 36.678 T 29-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 GBCGDNIH2_RS10135 644e119e1f26960f0a8677bc794788ae 375 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 1 351 1.3E-84 T 29-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 GBCGDNIH2_RS10135 644e119e1f26960f0a8677bc794788ae 375 Gene3D G3DSA:2.30.30.280 215 277 3.4E-11 T 29-03-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 Reactome: R-HSA-6787450 GBCGDNIH2_RS10135 644e119e1f26960f0a8677bc794788ae 375 Pfam PF03054 tRNA methyl transferase 1 351 1.6E-98 T 29-03-2018 GBCGDNIH2_RS09030 604ee6b5ac99024cc7f96d62f1f826be 295 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 9 247 5.8E-96 T 29-03-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112 GBCGDNIH2_RS09030 604ee6b5ac99024cc7f96d62f1f826be 295 SUPERFAMILY SSF53167 7 274 3.71E-95 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 GBCGDNIH2_RS09030 604ee6b5ac99024cc7f96d62f1f826be 295 Pfam PF01048 Phosphorylase superfamily 9 247 1.7E-44 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 GBCGDNIH2_RS09030 604ee6b5ac99024cc7f96d62f1f826be 295 Gene3D G3DSA:3.40.50.1580 1 270 4.7E-53 T 29-03-2018 GBCGDNIH2_RS09030 604ee6b5ac99024cc7f96d62f1f826be 295 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 55 95 - T 29-03-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 GBCGDNIH2_RS09030 604ee6b5ac99024cc7f96d62f1f826be 295 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 7 270 41.787 T 29-03-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112 GBCGDNIH2_RS11215 c80bc99c5bd349e6136505c339b73bb6 142 SUPERFAMILY SSF51316 18 141 6.28E-57 T 29-03-2018 IPR011057 Mss4-like GBCGDNIH2_RS11215 c80bc99c5bd349e6136505c339b73bb6 142 Gene3D G3DSA:2.170.150.20 10 142 1.0E-57 T 29-03-2018 GBCGDNIH2_RS11215 c80bc99c5bd349e6136505c339b73bb6 142 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 19 140 1.3E-50 T 29-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 GBCGDNIH2_RS11215 c80bc99c5bd349e6136505c339b73bb6 142 Pfam PF01641 SelR domain 22 139 1.9E-50 T 29-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 GBCGDNIH2_RS11425 1c3f794fd5c75d1bcaf70945e95630b1 489 SUPERFAMILY SSF53187 167 486 1.66E-117 T 29-03-2018 GBCGDNIH2_RS11425 1c3f794fd5c75d1bcaf70945e95630b1 489 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 2 488 34.929 T 29-03-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 GBCGDNIH2_RS11425 1c3f794fd5c75d1bcaf70945e95630b1 489 Gene3D G3DSA:3.40.220.10 1 148 2.1E-28 T 29-03-2018 GBCGDNIH2_RS11425 1c3f794fd5c75d1bcaf70945e95630b1 489 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 173 479 9.1E-123 T 29-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 GBCGDNIH2_RS11425 1c3f794fd5c75d1bcaf70945e95630b1 489 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 28 135 3.6E-19 T 29-03-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 GBCGDNIH2_RS11425 1c3f794fd5c75d1bcaf70945e95630b1 489 Gene3D G3DSA:3.40.630.10 157 489 1.3E-134 T 29-03-2018 GBCGDNIH2_RS11425 1c3f794fd5c75d1bcaf70945e95630b1 489 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 335 342 - T 29-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 GBCGDNIH2_RS11425 1c3f794fd5c75d1bcaf70945e95630b1 489 SUPERFAMILY SSF52949 9 171 2.59E-23 T 29-03-2018 GBCGDNIH2_RS11425 1c3f794fd5c75d1bcaf70945e95630b1 489 PRINTS PR00481 Cytosol aminopeptidase signature 360 375 7.3E-51 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 GBCGDNIH2_RS11425 1c3f794fd5c75d1bcaf70945e95630b1 489 PRINTS PR00481 Cytosol aminopeptidase signature 272 293 7.3E-51 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 GBCGDNIH2_RS11425 1c3f794fd5c75d1bcaf70945e95630b1 489 PRINTS PR00481 Cytosol aminopeptidase signature 250 267 7.3E-51 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 GBCGDNIH2_RS11425 1c3f794fd5c75d1bcaf70945e95630b1 489 PRINTS PR00481 Cytosol aminopeptidase signature 331 351 7.3E-51 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 GBCGDNIH2_RS11425 1c3f794fd5c75d1bcaf70945e95630b1 489 PRINTS PR00481 Cytosol aminopeptidase signature 309 330 7.3E-51 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 GBCGDNIH2_RS12085 1ffba06b0b98cc754d1ed5c63186821f 171 Pfam PF02556 Preprotein translocase subunit SecB 16 163 3.1E-52 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 GBCGDNIH2_RS12085 1ffba06b0b98cc754d1ed5c63186821f 171 TIGRFAM TIGR00809 secB: protein-export chaperone SecB 19 162 9.0E-42 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 GBCGDNIH2_RS12085 1ffba06b0b98cc754d1ed5c63186821f 171 SUPERFAMILY SSF54611 11 159 3.71E-43 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 GBCGDNIH2_RS12085 1ffba06b0b98cc754d1ed5c63186821f 171 Gene3D G3DSA:3.10.420.10 11 171 5.3E-48 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 GBCGDNIH2_RS12085 1ffba06b0b98cc754d1ed5c63186821f 171 Hamap MF_00821 Protein-export protein SecB [secB]. 1 164 31.59 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 GBCGDNIH2_RS12085 1ffba06b0b98cc754d1ed5c63186821f 171 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 23 40 3.7E-9 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 GBCGDNIH2_RS12085 1ffba06b0b98cc754d1ed5c63186821f 171 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 142 160 3.7E-9 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 GBCGDNIH2_RS06860 ffc0f8d9ae9f10dd8f6c6f4d43f9d195 258 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 4 235 41.165 T 29-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS06860 ffc0f8d9ae9f10dd8f6c6f4d43f9d195 258 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 7 225 7.0E-98 T 29-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS06860 ffc0f8d9ae9f10dd8f6c6f4d43f9d195 258 Pfam PF00318 Ribosomal protein S2 11 225 2.4E-92 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS06860 ffc0f8d9ae9f10dd8f6c6f4d43f9d195 258 SUPERFAMILY SSF52313 8 231 1.7E-89 T 29-03-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain GBCGDNIH2_RS06860 ffc0f8d9ae9f10dd8f6c6f4d43f9d195 258 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 8 19 - T 29-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 GBCGDNIH2_RS06860 ffc0f8d9ae9f10dd8f6c6f4d43f9d195 258 PRINTS PR00395 Ribosomal protein S2 signature 159 176 4.3E-39 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS06860 ffc0f8d9ae9f10dd8f6c6f4d43f9d195 258 PRINTS PR00395 Ribosomal protein S2 signature 8 26 4.3E-39 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS06860 ffc0f8d9ae9f10dd8f6c6f4d43f9d195 258 PRINTS PR00395 Ribosomal protein S2 signature 176 187 4.3E-39 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS06860 ffc0f8d9ae9f10dd8f6c6f4d43f9d195 258 PRINTS PR00395 Ribosomal protein S2 signature 197 211 4.3E-39 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS06860 ffc0f8d9ae9f10dd8f6c6f4d43f9d195 258 PRINTS PR00395 Ribosomal protein S2 signature 89 106 4.3E-39 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS06860 ffc0f8d9ae9f10dd8f6c6f4d43f9d195 258 PRINTS PR00395 Ribosomal protein S2 signature 39 48 4.3E-39 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS06860 ffc0f8d9ae9f10dd8f6c6f4d43f9d195 258 Gene3D G3DSA:3.40.50.10490 7 258 6.8E-92 T 29-03-2018 GBCGDNIH2_RS06860 ffc0f8d9ae9f10dd8f6c6f4d43f9d195 258 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 159 183 - T 29-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 GBCGDNIH2_RS02250 cadc1c243040f17f7cb8df4b875f37ce 329 Pfam PF01795 MraW methylase family 18 321 8.3E-103 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 GBCGDNIH2_RS02250 cadc1c243040f17f7cb8df4b875f37ce 329 SUPERFAMILY SSF53335 19 126 2.75E-47 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GBCGDNIH2_RS02250 cadc1c243040f17f7cb8df4b875f37ce 329 SUPERFAMILY SSF53335 225 321 2.75E-47 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GBCGDNIH2_RS02250 cadc1c243040f17f7cb8df4b875f37ce 329 Gene3D G3DSA:1.10.150.170 127 220 4.7E-35 T 29-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 GBCGDNIH2_RS02250 cadc1c243040f17f7cb8df4b875f37ce 329 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 18 321 1.1E-97 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 GBCGDNIH2_RS02250 cadc1c243040f17f7cb8df4b875f37ce 329 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 19 323 37.737 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 GBCGDNIH2_RS02250 cadc1c243040f17f7cb8df4b875f37ce 329 PIRSF PIRSF004486 13 324 3.9E-104 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 GBCGDNIH2_RS02250 cadc1c243040f17f7cb8df4b875f37ce 329 Gene3D G3DSA:3.40.50.150 221 318 0.0021 T 29-03-2018 GBCGDNIH2_RS02250 cadc1c243040f17f7cb8df4b875f37ce 329 Gene3D G3DSA:3.40.50.150 12 126 2.8E-4 T 29-03-2018 GBCGDNIH2_RS02250 cadc1c243040f17f7cb8df4b875f37ce 329 SUPERFAMILY SSF81799 127 225 8.89E-33 T 29-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 GBCGDNIH2_RS07610 95d688f9df1980911449fd80e630242d 262 Gene3D G3DSA:3.40.50.150 17 257 8.8E-17 T 29-03-2018 GBCGDNIH2_RS07610 95d688f9df1980911449fd80e630242d 262 SUPERFAMILY SSF53335 51 189 1.17E-21 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GBCGDNIH2_RS06700 19bcc383e5c8e4759523fe3ec751d222 217 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 13 146 2.6E-33 T 29-03-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase GBCGDNIH2_RS11385 45df23fd9155732283da62399529d22a 78 Pfam PF06568 Domain of unknown function (DUF1127) 36 70 7.7E-9 T 29-03-2018 IPR009506 Protein of unknown function DUF1127 GBCGDNIH2_RS11720 0a31502f30eb4ba9bdee81fba51a100f 243 Gene3D G3DSA:1.10.10.60 2 47 1.4E-5 T 29-03-2018 GBCGDNIH2_RS11720 0a31502f30eb4ba9bdee81fba51a100f 243 Pfam PF07750 GcrA cell cycle regulator 1 116 1.6E-17 T 29-03-2018 IPR011681 GcrA cell cycle regulator GBCGDNIH2_RS11720 0a31502f30eb4ba9bdee81fba51a100f 243 Pfam PF07750 GcrA cell cycle regulator 197 239 8.9E-11 T 29-03-2018 IPR011681 GcrA cell cycle regulator GBCGDNIH2_RS07955 0ead4ef1e9665017c7225363b8fccfd4 418 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 9 388 4.0E-98 T 29-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 GBCGDNIH2_RS07955 0ead4ef1e9665017c7225363b8fccfd4 418 TIGRFAM TIGR01579 MiaB-like-C: MiaB-like tRNA modifying enzyme 11 383 1.9E-121 T 29-03-2018 IPR006467 MiaB-like tRNA modifying enzyme GO:0016740 GBCGDNIH2_RS07955 0ead4ef1e9665017c7225363b8fccfd4 418 Gene3D G3DSA:3.20.20.70 44 366 4.0E-49 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS07955 0ead4ef1e9665017c7225363b8fccfd4 418 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 136 156 - T 29-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 GBCGDNIH2_RS07955 0ead4ef1e9665017c7225363b8fccfd4 418 Pfam PF04055 Radical SAM superfamily 137 309 3.4E-22 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 GBCGDNIH2_RS07955 0ead4ef1e9665017c7225363b8fccfd4 418 SMART SM00729 132 350 4.4E-53 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 GBCGDNIH2_RS07955 0ead4ef1e9665017c7225363b8fccfd4 418 Pfam PF00919 Uncharacterized protein family UPF0004 9 85 7.9E-15 T 29-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 GBCGDNIH2_RS07955 0ead4ef1e9665017c7225363b8fccfd4 418 SUPERFAMILY SSF102114 111 353 2.09E-56 T 29-03-2018 GBCGDNIH2_RS03875 0daf6953f8d7d20a1468fc0986c3ebdf 985 Gene3D G3DSA:2.60.40.1180 891 985 1.1E-23 T 29-03-2018 GBCGDNIH2_RS03875 0daf6953f8d7d20a1468fc0986c3ebdf 985 Pfam PF11896 Domain of unknown function (DUF3416) 349 525 9.2E-55 T 29-03-2018 IPR021828 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase, domain N/S GO:0004553 KEGG: 00500+2.4.99.16 GBCGDNIH2_RS03875 0daf6953f8d7d20a1468fc0986c3ebdf 985 SUPERFAMILY SSF51445 518 887 2.23E-91 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily GBCGDNIH2_RS03875 0daf6953f8d7d20a1468fc0986c3ebdf 985 SMART SM00642 535 874 1.3E-5 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 GBCGDNIH2_RS03875 0daf6953f8d7d20a1468fc0986c3ebdf 985 Pfam PF00128 Alpha amylase, catalytic domain 549 654 2.6E-5 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 GBCGDNIH2_RS03875 0daf6953f8d7d20a1468fc0986c3ebdf 985 Hamap MF_02124 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase [glgE]. 346 983 46.992 T 29-03-2018 IPR026585 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase GO:0016757 KEGG: 00500+2.4.99.16 GBCGDNIH2_RS03875 0daf6953f8d7d20a1468fc0986c3ebdf 985 Gene3D G3DSA:3.20.20.80 526 890 1.4E-64 T 29-03-2018 GBCGDNIH2_RS03875 0daf6953f8d7d20a1468fc0986c3ebdf 985 Gene3D G3DSA:1.20.58.280 444 515 8.4E-10 T 29-03-2018 GBCGDNIH2_RS03875 0daf6953f8d7d20a1468fc0986c3ebdf 985 Gene3D G3DSA:2.60.40.10 346 443 1.6E-32 T 29-03-2018 IPR013783 Immunoglobulin-like fold GBCGDNIH2_RS05945 6c09a983c070ce82aced6789a9f65733 204 SMART SM00278 108 127 22.0 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 GBCGDNIH2_RS05945 6c09a983c070ce82aced6789a9f65733 204 SMART SM00278 73 92 56.0 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 GBCGDNIH2_RS05945 6c09a983c070ce82aced6789a9f65733 204 Pfam PF01330 RuvA N terminal domain 1 62 4.9E-16 T 29-03-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 GBCGDNIH2_RS05945 6c09a983c070ce82aced6789a9f65733 204 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 202 26.679 T 29-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 GBCGDNIH2_RS05945 6c09a983c070ce82aced6789a9f65733 204 Pfam PF07499 RuvA, C-terminal domain 156 201 1.8E-9 T 29-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 GBCGDNIH2_RS05945 6c09a983c070ce82aced6789a9f65733 204 SUPERFAMILY SSF46929 155 202 1.57E-7 T 29-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 GBCGDNIH2_RS05945 6c09a983c070ce82aced6789a9f65733 204 Gene3D G3DSA:1.10.150.20 67 138 1.5E-13 T 29-03-2018 GBCGDNIH2_RS05945 6c09a983c070ce82aced6789a9f65733 204 Pfam PF14520 Helix-hairpin-helix domain 72 130 1.2E-12 T 29-03-2018 GBCGDNIH2_RS05945 6c09a983c070ce82aced6789a9f65733 204 Gene3D G3DSA:2.40.50.140 1 66 1.1E-20 T 29-03-2018 GBCGDNIH2_RS05945 6c09a983c070ce82aced6789a9f65733 204 SUPERFAMILY SSF50249 1 63 1.94E-14 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold GBCGDNIH2_RS05945 6c09a983c070ce82aced6789a9f65733 204 SUPERFAMILY SSF47781 65 133 3.71E-19 T 29-03-2018 IPR010994 RuvA domain 2-like GBCGDNIH2_RS05945 6c09a983c070ce82aced6789a9f65733 204 Gene3D G3DSA:1.10.8.10 147 204 2.2E-11 T 29-03-2018 GBCGDNIH2_RS01390 da925ff41a41964758bbe477bb80d97a 153 Gene3D G3DSA:3.10.590.10 1 152 8.1E-51 T 29-03-2018 GBCGDNIH2_RS01390 da925ff41a41964758bbe477bb80d97a 153 Pfam PF01878 EVE domain 3 141 1.5E-45 T 29-03-2018 IPR002740 EVE domain GBCGDNIH2_RS01390 da925ff41a41964758bbe477bb80d97a 153 SUPERFAMILY SSF88697 3 143 6.46E-50 T 29-03-2018 IPR015947 PUA-like domain GBCGDNIH2_RS07695 469b7ec9395213a6ed48b8f20ce95640 906 PRINTS PR00723 Subtilisin serine protease family (S8) signature 42 61 2.2E-16 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related GBCGDNIH2_RS07695 469b7ec9395213a6ed48b8f20ce95640 906 PRINTS PR00723 Subtilisin serine protease family (S8) signature 85 98 2.2E-16 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related GBCGDNIH2_RS07695 469b7ec9395213a6ed48b8f20ce95640 906 PRINTS PR00723 Subtilisin serine protease family (S8) signature 295 311 2.2E-16 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related GBCGDNIH2_RS07695 469b7ec9395213a6ed48b8f20ce95640 906 Gene3D G3DSA:2.150.10.10 742 904 8.4E-10 T 29-03-2018 GBCGDNIH2_RS07695 469b7ec9395213a6ed48b8f20ce95640 906 Gene3D G3DSA:2.150.10.10 654 741 0.0026 T 29-03-2018 GBCGDNIH2_RS07695 469b7ec9395213a6ed48b8f20ce95640 906 SUPERFAMILY SSF52743 3 375 1.15E-65 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 GBCGDNIH2_RS07695 469b7ec9395213a6ed48b8f20ce95640 906 Gene3D G3DSA:3.40.50.200 1 379 3.6E-69 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 GBCGDNIH2_RS07695 469b7ec9395213a6ed48b8f20ce95640 906 Gene3D G3DSA:2.60.120.260 392 653 1.8E-13 T 29-03-2018 IPR008979 Galactose-binding domain-like GBCGDNIH2_RS07695 469b7ec9395213a6ed48b8f20ce95640 906 Pfam PF01483 Proprotein convertase P-domain 428 520 3.2E-6 T 29-03-2018 IPR002884 Proprotein convertase, P GO:0004252|GO:0006508 GBCGDNIH2_RS07695 469b7ec9395213a6ed48b8f20ce95640 906 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 89 99 - T 29-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site GBCGDNIH2_RS07695 469b7ec9395213a6ed48b8f20ce95640 906 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 296 306 - T 29-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site GBCGDNIH2_RS07695 469b7ec9395213a6ed48b8f20ce95640 906 SUPERFAMILY SSF49785 410 530 1.53E-10 T 29-03-2018 IPR008979 Galactose-binding domain-like GBCGDNIH2_RS07695 469b7ec9395213a6ed48b8f20ce95640 906 SUPERFAMILY SSF51120 649 791 4.19E-9 T 29-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal GBCGDNIH2_RS07695 469b7ec9395213a6ed48b8f20ce95640 906 Pfam PF00082 Subtilase family 42 340 2.5E-36 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 GBCGDNIH2_RS07695 469b7ec9395213a6ed48b8f20ce95640 906 SUPERFAMILY SSF51120 750 878 1.55E-8 T 29-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal GBCGDNIH2_RS11405 3595d39308caf7f40ab9adddb5e7ed4a 370 TIGRFAM TIGR04408 LptG_lptG: LPS export ABC transporter permease LptG 6 366 5.8E-83 T 29-03-2018 IPR030923 LPS export ABC transporter permease LptG GO:0043190|GO:0055085 GBCGDNIH2_RS11405 3595d39308caf7f40ab9adddb5e7ed4a 370 Pfam PF03739 Predicted permease YjgP/YjgQ family 10 365 7.7E-59 T 29-03-2018 IPR005495 Permease LptG/LptF-related GO:0016021 GBCGDNIH2_RS08015 5acf1ea2f851c3a8755e9fde138d0e03 68 Gene3D G3DSA:1.10.10.10 10 68 8.6E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS08015 5acf1ea2f851c3a8755e9fde138d0e03 68 Pfam PF05930 Prophage CP4-57 regulatory protein (AlpA) 11 59 6.0E-9 T 29-03-2018 IPR010260 DNA-binding transcriptional activator AlpA GBCGDNIH2_RS10935 0d376ae388638891423a33c0fbefe81b 88 Pfam PF07704 Rv0623-like transcription factor 5 87 1.7E-22 T 29-03-2018 IPR011660 Antitoxin VapB-like GBCGDNIH2_RS09980 41d54628498a504c2fb93c08934c9152 267 SMART SM00382 50 227 1.2E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS09980 41d54628498a504c2fb93c08934c9152 267 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GBCGDNIH2_RS09980 41d54628498a504c2fb93c08934c9152 267 Pfam PF00005 ABC transporter 41 179 1.0E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GBCGDNIH2_RS09980 41d54628498a504c2fb93c08934c9152 267 SUPERFAMILY SSF52540 36 226 1.45E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS09980 41d54628498a504c2fb93c08934c9152 267 Gene3D G3DSA:3.40.50.300 15 264 1.7E-50 T 29-03-2018 GBCGDNIH2_RS04355 27841ce96f477f0c521ab80fb4089d1a 330 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 145 159 - T 29-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 GBCGDNIH2_RS04355 27841ce96f477f0c521ab80fb4089d1a 330 SUPERFAMILY SSF55174 23 111 2.94E-9 T 29-03-2018 GBCGDNIH2_RS04355 27841ce96f477f0c521ab80fb4089d1a 330 Gene3D G3DSA:3.30.2350.10 90 330 7.9E-67 T 29-03-2018 GBCGDNIH2_RS04355 27841ce96f477f0c521ab80fb4089d1a 330 SMART SM00363 24 83 0.0053 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 GBCGDNIH2_RS04355 27841ce96f477f0c521ab80fb4089d1a 330 Pfam PF01479 S4 domain 24 68 7.1E-5 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 GBCGDNIH2_RS04355 27841ce96f477f0c521ab80fb4089d1a 330 SUPERFAMILY SSF55120 86 328 1.27E-70 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 GBCGDNIH2_RS04355 27841ce96f477f0c521ab80fb4089d1a 330 Gene3D G3DSA:3.10.290.10 8 82 2.3E-16 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 GBCGDNIH2_RS04355 27841ce96f477f0c521ab80fb4089d1a 330 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 24 325 1.9E-83 T 29-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 GBCGDNIH2_RS04355 27841ce96f477f0c521ab80fb4089d1a 330 Pfam PF00849 RNA pseudouridylate synthase 98 255 6.6E-30 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 GBCGDNIH2_RS04965 dfaf3e051fdcbf69f8bbe92d98289a35 260 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 14 260 8.7E-117 T 29-03-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 GBCGDNIH2_RS04965 dfaf3e051fdcbf69f8bbe92d98289a35 260 SMART SM00382 38 240 1.3E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS04965 dfaf3e051fdcbf69f8bbe92d98289a35 260 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GBCGDNIH2_RS04965 dfaf3e051fdcbf69f8bbe92d98289a35 260 Pfam PF00005 ABC transporter 29 185 4.3E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GBCGDNIH2_RS04965 dfaf3e051fdcbf69f8bbe92d98289a35 260 Gene3D G3DSA:3.40.50.300 9 256 1.1E-62 T 29-03-2018 GBCGDNIH2_RS04965 dfaf3e051fdcbf69f8bbe92d98289a35 260 SUPERFAMILY SSF52540 12 247 1.56E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS11605 80ee90c5313e12e434703c0ddd3c047d 180 Gene3D G3DSA:1.10.10.10 16 169 6.0E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS11605 80ee90c5313e12e434703c0ddd3c047d 180 Pfam PF12802 MarR family 53 112 4.7E-15 T 29-03-2018 GBCGDNIH2_RS11605 80ee90c5313e12e434703c0ddd3c047d 180 SMART SM00347 48 148 5.9E-18 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GBCGDNIH2_RS11605 80ee90c5313e12e434703c0ddd3c047d 180 ProSitePatterns PS01117 MarR-type HTH domain signature. 87 121 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site GBCGDNIH2_RS11605 80ee90c5313e12e434703c0ddd3c047d 180 SUPERFAMILY SSF46785 33 160 2.81E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS11605 80ee90c5313e12e434703c0ddd3c047d 180 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 104 3.0E-7 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GBCGDNIH2_RS11605 80ee90c5313e12e434703c0ddd3c047d 180 PRINTS PR00598 Bacterial regulatory protein MarR family signature 72 88 3.0E-7 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GBCGDNIH2_RS11605 80ee90c5313e12e434703c0ddd3c047d 180 PRINTS PR00598 Bacterial regulatory protein MarR family signature 108 124 3.0E-7 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GBCGDNIH2_RS02405 fb37d160a30beda5f87a39896b657ba9 572 Gene3D G3DSA:1.10.1370.10 57 558 7.4E-43 T 29-03-2018 GBCGDNIH2_RS02405 fb37d160a30beda5f87a39896b657ba9 572 SUPERFAMILY SSF55486 34 565 1.18E-82 T 29-03-2018 GBCGDNIH2_RS02405 fb37d160a30beda5f87a39896b657ba9 572 Pfam PF01432 Peptidase family M3 168 271 3.2E-5 T 29-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 GBCGDNIH2_RS02405 fb37d160a30beda5f87a39896b657ba9 572 Pfam PF01432 Peptidase family M3 322 548 1.3E-20 T 29-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 GBCGDNIH2_RS07255 190a99479ac7ee3c45b2f65f5512f773 286 Gene3D G3DSA:3.40.1190.20 1 274 2.4E-59 T 29-03-2018 IPR029056 Ribokinase-like GBCGDNIH2_RS07255 190a99479ac7ee3c45b2f65f5512f773 286 Hamap MF_01639 Pyridoxal kinase PdxY [pdxY]. 1 286 49.828 T 29-03-2018 IPR023685 Pyridoxal kinase PdxY GO:0008478|GO:0009443 KEGG: 00750+2.7.1.35|MetaCyc: PWY-7204|MetaCyc: PWY-7282 GBCGDNIH2_RS07255 190a99479ac7ee3c45b2f65f5512f773 286 SUPERFAMILY SSF53613 3 265 9.51E-66 T 29-03-2018 IPR029056 Ribokinase-like GBCGDNIH2_RS07255 190a99479ac7ee3c45b2f65f5512f773 286 Pfam PF08543 Phosphomethylpyrimidine kinase 90 262 6.4E-17 T 29-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 GBCGDNIH2_RS07255 190a99479ac7ee3c45b2f65f5512f773 286 TIGRFAM TIGR00687 pyridox_kin: pyridoxal kinase 2 283 1.3E-101 T 29-03-2018 IPR004625 Pyridoxine kinase GO:0008478|GO:0009443 KEGG: 00750+2.7.1.35|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-6798695|Reactome: R-HSA-964975 GBCGDNIH2_RS09140 6cb45269dc79b12182f897e2e0b58442 303 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 40 276 9.6E-61 T 29-03-2018 IPR022488 Polyphosphate kinase-2-related GBCGDNIH2_RS09140 6cb45269dc79b12182f897e2e0b58442 303 TIGRFAM TIGR03709 PPK2_rel_1: polyphosphate:nucleotide phosphotransferase, PPK2 family 15 286 9.4E-110 T 29-03-2018 IPR022300 Polyphosphate:nucleotide phosphotransferase, PPK2 GO:0006797|GO:0016776 GBCGDNIH2_RS09140 6cb45269dc79b12182f897e2e0b58442 303 PIRSF PIRSF028756 14 303 2.6E-73 T 29-03-2018 IPR016898 Polyphosphate kinase 2 GBCGDNIH2_RS09140 6cb45269dc79b12182f897e2e0b58442 303 SUPERFAMILY SSF52540 125 274 4.96E-11 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS09140 6cb45269dc79b12182f897e2e0b58442 303 Gene3D G3DSA:3.40.50.300 4 298 4.7E-72 T 29-03-2018 GBCGDNIH2_RS09760 ebb2be77e8c591a1f0d502f7122894f8 186 SMART SM00248 29 58 150.0 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 GBCGDNIH2_RS09760 ebb2be77e8c591a1f0d502f7122894f8 186 SMART SM00248 128 157 3.4E-4 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 GBCGDNIH2_RS09760 ebb2be77e8c591a1f0d502f7122894f8 186 SMART SM00248 95 124 1.8 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 GBCGDNIH2_RS09760 ebb2be77e8c591a1f0d502f7122894f8 186 SMART SM00248 62 91 9.7 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 GBCGDNIH2_RS09760 ebb2be77e8c591a1f0d502f7122894f8 186 Pfam PF12796 Ankyrin repeats (3 copies) 67 159 3.6E-13 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain GBCGDNIH2_RS09760 ebb2be77e8c591a1f0d502f7122894f8 186 SUPERFAMILY SSF48403 35 182 6.36E-35 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain GBCGDNIH2_RS09760 ebb2be77e8c591a1f0d502f7122894f8 186 Gene3D G3DSA:1.25.40.20 118 185 1.1E-19 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain GBCGDNIH2_RS09760 ebb2be77e8c591a1f0d502f7122894f8 186 Gene3D G3DSA:1.25.40.20 24 117 1.0E-24 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain GBCGDNIH2_RS06780 8d50bf509cbda6525bc416929c473bbc 381 SMART SM00471 57 205 1.0E-12 T 29-03-2018 IPR003607 HD/PDEase domain GBCGDNIH2_RS06780 8d50bf509cbda6525bc416929c473bbc 381 SUPERFAMILY SSF109604 12 375 1.75E-88 T 29-03-2018 GBCGDNIH2_RS06780 8d50bf509cbda6525bc416929c473bbc 381 Pfam PF01966 HD domain 61 191 4.3E-16 T 29-03-2018 IPR006674 HD domain GBCGDNIH2_RS06780 8d50bf509cbda6525bc416929c473bbc 381 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 24 375 1.9E-100 T 29-03-2018 IPR006261 dNTP triphosphohydrolase GO:0016793 GBCGDNIH2_RS06780 8d50bf509cbda6525bc416929c473bbc 381 TIGRFAM TIGR00277 HDIG: HDIG domain 62 98 4.0E-7 T 29-03-2018 IPR006675 HDIG domain GBCGDNIH2_RS06780 8d50bf509cbda6525bc416929c473bbc 381 Gene3D G3DSA:1.10.3210.10 19 378 4.0E-81 T 29-03-2018 GBCGDNIH2_RS06780 8d50bf509cbda6525bc416929c473bbc 381 Hamap MF_01212 Deoxyguanosinetriphosphate triphosphohydrolase-like protein. 1 375 39.099 T 29-03-2018 IPR023023 dNTP triphosphohydrolase, type 2 GO:0016793 GBCGDNIH2_RS06780 8d50bf509cbda6525bc416929c473bbc 381 Pfam PF13286 Phosphohydrolase-associated domain 282 373 1.3E-27 T 29-03-2018 IPR026875 Phosphohydrolase-associated domain GBCGDNIH2_RS07340 b7d0d42c3893b8ba6b375e1af4b7115f 315 Pfam PF01867 CRISPR associated protein Cas1 27 128 1.9E-5 T 29-03-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 GBCGDNIH2_RS07340 b7d0d42c3893b8ba6b375e1af4b7115f 315 Pfam PF01867 CRISPR associated protein Cas1 136 232 4.8E-6 T 29-03-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 GBCGDNIH2_RS07340 b7d0d42c3893b8ba6b375e1af4b7115f 315 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 21 291 17.177 T 29-03-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 GBCGDNIH2_RS07340 b7d0d42c3893b8ba6b375e1af4b7115f 315 TIGRFAM TIGR03638 cas1_ECOLI: CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI 16 284 1.9E-106 T 29-03-2018 IPR019851 CRISPR-associated protein Cas1, ECOLI subtype GO:0004520|GO:0043571|GO:0046872 GBCGDNIH2_RS07340 b7d0d42c3893b8ba6b375e1af4b7115f 315 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 139 246 1.1E-25 T 29-03-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 GBCGDNIH2_RS03295 39d9bf99fc636f92f7414a5da0f61661 558 PIRSF PIRSF006281 23 554 4.1E-167 T 29-03-2018 IPR014438 Glucan biosynthesis, periplasmic, MdoG/D GBCGDNIH2_RS03295 39d9bf99fc636f92f7414a5da0f61661 558 SUPERFAMILY SSF74650 54 421 3.77E-143 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 GBCGDNIH2_RS03295 39d9bf99fc636f92f7414a5da0f61661 558 Gene3D G3DSA:2.60.40.10 425 554 1.5E-17 T 29-03-2018 IPR013783 Immunoglobulin-like fold GBCGDNIH2_RS03295 39d9bf99fc636f92f7414a5da0f61661 558 Pfam PF04349 Periplasmic glucan biosynthesis protein, MdoG 54 550 2.1E-169 T 29-03-2018 IPR007444 Glucan biosynthesis, periplasmic, MdoG C-terminal GO:0016051|GO:0042597 GBCGDNIH2_RS03295 39d9bf99fc636f92f7414a5da0f61661 558 SUPERFAMILY SSF81296 426 552 4.34E-9 T 29-03-2018 IPR014756 Immunoglobulin E-set GBCGDNIH2_RS03295 39d9bf99fc636f92f7414a5da0f61661 558 Gene3D G3DSA:2.70.98.10 54 422 4.7E-152 T 29-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 GBCGDNIH2_RS01515 a556f320c58580bbd7f898543da4bc84 308 Gene3D G3DSA:3.40.190.10 84 179 1.8E-18 T 29-03-2018 GBCGDNIH2_RS01515 a556f320c58580bbd7f898543da4bc84 308 Gene3D G3DSA:3.40.190.10 180 267 7.3E-24 T 29-03-2018 GBCGDNIH2_RS01515 a556f320c58580bbd7f898543da4bc84 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 66 3.2E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS01515 a556f320c58580bbd7f898543da4bc84 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 6.2E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS01515 a556f320c58580bbd7f898543da4bc84 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 6.2E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS01515 a556f320c58580bbd7f898543da4bc84 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 6.2E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS01515 a556f320c58580bbd7f898543da4bc84 308 SUPERFAMILY SSF53850 93 299 2.35E-39 T 29-03-2018 GBCGDNIH2_RS01515 a556f320c58580bbd7f898543da4bc84 308 Gene3D G3DSA:1.10.10.10 5 83 1.6E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS01515 a556f320c58580bbd7f898543da4bc84 308 Pfam PF03466 LysR substrate binding domain 91 295 2.6E-38 T 29-03-2018 IPR005119 LysR, substrate-binding GBCGDNIH2_RS01515 a556f320c58580bbd7f898543da4bc84 308 SUPERFAMILY SSF46785 5 115 8.54E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS00505 e9022a41e7ab0bc9c60f8edf217ac430 156 Pfam PF03703 Bacterial PH domain 76 145 2.2E-16 T 29-03-2018 IPR005182 Domain of unknown function DUF304 GBCGDNIH2_RS08890 025a8984d48501e509d25bd47440b6fc 218 PIRSF PIRSF006324 1 216 2.4E-41 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 GBCGDNIH2_RS08890 025a8984d48501e509d25bd47440b6fc 218 Pfam PF01810 LysE type translocator 17 214 1.7E-29 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 GBCGDNIH2_RS12665 522032b47f54b517e17fc5a0455f067a 187 SUPERFAMILY SSF46955 10 77 3.07E-14 T 29-03-2018 IPR009061 Putative DNA-binding domain GBCGDNIH2_RS12665 522032b47f54b517e17fc5a0455f067a 187 SMART SM00422 10 79 0.0027 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 GBCGDNIH2_RS12665 522032b47f54b517e17fc5a0455f067a 187 Gene3D G3DSA:1.10.1660.10 1 186 2.0E-29 T 29-03-2018 GBCGDNIH2_RS12665 522032b47f54b517e17fc5a0455f067a 187 Pfam PF13411 MerR HTH family regulatory protein 10 78 2.8E-24 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 GBCGDNIH2_RS04995 966fbefbcc0d56a4acd24593bab966c7 261 Gene3D G3DSA:3.90.1720.10 5 159 2.1E-4 T 29-03-2018 GBCGDNIH2_RS04995 966fbefbcc0d56a4acd24593bab966c7 261 Pfam PF05257 CHAP domain 44 113 2.8E-9 T 29-03-2018 IPR007921 CHAP domain GBCGDNIH2_RS04995 966fbefbcc0d56a4acd24593bab966c7 261 SUPERFAMILY SSF54001 28 162 1.57E-20 T 29-03-2018 GBCGDNIH2_RS01490 f6034ee9fb20a5d056eb1404bdc528cf 375 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 7 358 1.0E-138 T 29-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 GBCGDNIH2_RS01490 f6034ee9fb20a5d056eb1404bdc528cf 375 Pfam PF01702 Queuine tRNA-ribosyltransferase 129 357 5.1E-85 T 29-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 GBCGDNIH2_RS01490 f6034ee9fb20a5d056eb1404bdc528cf 375 SUPERFAMILY SSF51713 3 357 6.28E-147 T 29-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 GBCGDNIH2_RS01490 f6034ee9fb20a5d056eb1404bdc528cf 375 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 6 359 4.5E-144 T 29-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 GBCGDNIH2_RS01490 f6034ee9fb20a5d056eb1404bdc528cf 375 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 3 364 51.289 T 29-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 GBCGDNIH2_RS01490 f6034ee9fb20a5d056eb1404bdc528cf 375 Gene3D G3DSA:3.20.20.105 1 365 4.9E-144 T 29-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 GBCGDNIH2_RS02155 5fb503ec7e5774058072e628c866b498 309 Gene3D G3DSA:3.20.20.370 2 306 2.9E-64 T 29-03-2018 GBCGDNIH2_RS02155 5fb503ec7e5774058072e628c866b498 309 TIGRFAM TIGR03212 uraD_N-term-dom: putative urate catabolism protein 6 301 6.9E-159 T 29-03-2018 IPR017625 PuuE allantoinase/chitin deacetylase 1 GBCGDNIH2_RS02155 5fb503ec7e5774058072e628c866b498 309 SUPERFAMILY SSF88713 6 301 5.19E-94 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 GBCGDNIH2_RS02155 5fb503ec7e5774058072e628c866b498 309 Pfam PF01522 Polysaccharide deacetylase 78 165 1.5E-14 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 GBCGDNIH2_RS03630 93b6b69551a2ba3ff00df9fc5ae0a77f 251 Pfam PF02230 Phospholipase/Carboxylesterase 42 243 8.8E-23 T 29-03-2018 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 GBCGDNIH2_RS03630 93b6b69551a2ba3ff00df9fc5ae0a77f 251 Gene3D G3DSA:3.40.50.1820 33 251 3.1E-24 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS03630 93b6b69551a2ba3ff00df9fc5ae0a77f 251 SUPERFAMILY SSF53474 42 246 2.9E-30 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS11400 731fcd3ed2ad2696ea966c4b371917a0 826 Pfam PF03968 OstA-like protein 117 182 1.5E-4 T 29-03-2018 IPR005653 Organic solvent tolerance-like, N-terminal GBCGDNIH2_RS11400 731fcd3ed2ad2696ea966c4b371917a0 826 Pfam PF04453 Organic solvent tolerance protein 374 721 4.6E-51 T 29-03-2018 IPR007543 Organic solvent tolerance protein, C-terminal GO:0010033|GO:0019867|GO:0061024 GBCGDNIH2_RS11400 731fcd3ed2ad2696ea966c4b371917a0 826 Hamap MF_01411 LPS-assembly protein LptD [lptD]. 45 820 16.065 T 29-03-2018 IPR020889 LPS-assembly protein LptD GO:0009279|GO:0010033|GO:0015920|GO:0043165 GBCGDNIH2_RS11400 731fcd3ed2ad2696ea966c4b371917a0 826 Gene3D G3DSA:2.60.450.10 106 268 3.7E-17 T 29-03-2018 GBCGDNIH2_RS06030 55de8ae507c0d21f186ad20600c32a70 156 Gene3D G3DSA:3.40.50.2020 1 154 2.3E-23 T 29-03-2018 GBCGDNIH2_RS06030 55de8ae507c0d21f186ad20600c32a70 156 Pfam PF00156 Phosphoribosyl transferase domain 10 147 2.3E-18 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 GBCGDNIH2_RS06030 55de8ae507c0d21f186ad20600c32a70 156 SUPERFAMILY SSF53271 5 146 4.12E-28 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like GBCGDNIH2_RS06030 55de8ae507c0d21f186ad20600c32a70 156 Hamap MF_01903 Xanthine phosphoribosyltransferase [gpt]. 2 155 37.618 T 29-03-2018 IPR023747 Xanthine-guanine phosphoribosyltransferase GO:0000310 KEGG: 00230+2.4.2.22 GBCGDNIH2_RS09040 0dca5f21e9a92b2f48abdd7a397d9b15 528 SUPERFAMILY SSF103473 493 516 7.98E-66 T 29-03-2018 IPR020846 Major facilitator superfamily domain GBCGDNIH2_RS09040 0dca5f21e9a92b2f48abdd7a397d9b15 528 SUPERFAMILY SSF103473 263 433 7.98E-66 T 29-03-2018 IPR020846 Major facilitator superfamily domain GBCGDNIH2_RS09040 0dca5f21e9a92b2f48abdd7a397d9b15 528 SUPERFAMILY SSF103473 19 210 7.98E-66 T 29-03-2018 IPR020846 Major facilitator superfamily domain GBCGDNIH2_RS09040 0dca5f21e9a92b2f48abdd7a397d9b15 528 Gene3D G3DSA:1.20.1250.20 266 521 1.4E-24 T 29-03-2018 GBCGDNIH2_RS09040 0dca5f21e9a92b2f48abdd7a397d9b15 528 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 22 514 1.0E-129 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 GBCGDNIH2_RS09040 0dca5f21e9a92b2f48abdd7a397d9b15 528 Gene3D G3DSA:1.20.1250.20 16 213 2.9E-38 T 29-03-2018 GBCGDNIH2_RS09040 0dca5f21e9a92b2f48abdd7a397d9b15 528 Pfam PF07690 Major Facilitator Superfamily 27 423 1.7E-48 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 GBCGDNIH2_RS03650 a9aa332c26b9e5d8e4cb5f4e75a9ff37 189 Hamap MF_01658 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase [coq7]. 2 189 28.667 T 29-03-2018 IPR011566 Ubiquinone biosynthesis protein Coq7 GO:0006744|GO:0055114 Reactome: R-HSA-2142789 GBCGDNIH2_RS03650 a9aa332c26b9e5d8e4cb5f4e75a9ff37 189 Pfam PF03232 Ubiquinone biosynthesis protein COQ7 25 189 1.5E-68 T 29-03-2018 IPR011566 Ubiquinone biosynthesis protein Coq7 GO:0006744|GO:0055114 Reactome: R-HSA-2142789 GBCGDNIH2_RS03650 a9aa332c26b9e5d8e4cb5f4e75a9ff37 189 Gene3D G3DSA:1.20.1260.10 20 164 7.1E-32 T 29-03-2018 IPR012347 Ferritin-related GBCGDNIH2_RS03650 a9aa332c26b9e5d8e4cb5f4e75a9ff37 189 SUPERFAMILY SSF47240 25 156 3.25E-16 T 29-03-2018 IPR009078 Ferritin-like superfamily GBCGDNIH2_RS00570 0a344f9f88996eb79fd5ea339d503732 329 Gene3D G3DSA:3.40.50.20 5 141 2.8E-44 T 29-03-2018 GBCGDNIH2_RS00570 0a344f9f88996eb79fd5ea339d503732 329 SUPERFAMILY SSF56059 136 323 2.6E-58 T 29-03-2018 GBCGDNIH2_RS00570 0a344f9f88996eb79fd5ea339d503732 329 SUPERFAMILY SSF52440 5 134 3.16E-38 T 29-03-2018 IPR016185 Pre-ATP-grasp domain GBCGDNIH2_RS00570 0a344f9f88996eb79fd5ea339d503732 329 TIGRFAM TIGR01380 glut_syn: glutathione synthase 5 322 3.5E-123 T 29-03-2018 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 GBCGDNIH2_RS00570 0a344f9f88996eb79fd5ea339d503732 329 Gene3D G3DSA:3.30.1490.20 150 202 5.2E-21 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 GBCGDNIH2_RS00570 0a344f9f88996eb79fd5ea339d503732 329 Gene3D G3DSA:3.30.470.20 203 311 1.1E-16 T 29-03-2018 GBCGDNIH2_RS00570 0a344f9f88996eb79fd5ea339d503732 329 Pfam PF02951 Prokaryotic glutathione synthetase, N-terminal domain 5 132 1.1E-42 T 29-03-2018 IPR004215 Prokaryotic glutathione synthetase, N-terminal GO:0004363|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 GBCGDNIH2_RS00570 0a344f9f88996eb79fd5ea339d503732 329 Pfam PF02955 Prokaryotic glutathione synthetase, ATP-grasp domain 136 307 4.6E-71 T 29-03-2018 IPR004218 Prokaryotic glutathione synthetase, ATP-binding GO:0004363|GO:0005524|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 GBCGDNIH2_RS00570 0a344f9f88996eb79fd5ea339d503732 329 Hamap MF_00162 Glutathione synthetase [gshB]. 1 329 158.531 T 29-03-2018 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 GBCGDNIH2_RS09720 1b47ba1e335e299ec6b33e284183812f 209 SUPERFAMILY SSF53098 11 202 3.95E-60 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 GBCGDNIH2_RS09720 1b47ba1e335e299ec6b33e284183812f 209 Pfam PF01351 Ribonuclease HII 15 194 1.8E-35 T 29-03-2018 IPR024567 Ribonuclease HII/HIII domain GBCGDNIH2_RS09720 1b47ba1e335e299ec6b33e284183812f 209 Hamap MF_00052_B Ribonuclease HII [rnhB]. 13 197 35.077 T 29-03-2018 IPR022898 Ribonuclease HII GO:0004523 GBCGDNIH2_RS09720 1b47ba1e335e299ec6b33e284183812f 209 Gene3D G3DSA:3.30.420.10 3 209 5.7E-64 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 GBCGDNIH2_RS04050 6c49ed16faad3a4a0dbb5926e5f960cb 409 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 4 396 1.3E-83 T 29-03-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like GBCGDNIH2_RS04050 6c49ed16faad3a4a0dbb5926e5f960cb 409 SUPERFAMILY SSF51905 4 192 4.62E-41 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS04050 6c49ed16faad3a4a0dbb5926e5f960cb 409 SUPERFAMILY SSF51905 343 400 4.62E-41 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS04050 6c49ed16faad3a4a0dbb5926e5f960cb 409 TIGRFAM TIGR03862 flavo_PP4765: flavoprotein, TIGR03862 family 25 404 2.9E-152 T 29-03-2018 IPR022460 Conserved hyptotheical protein CHP03862, flavoprotein, PP4765 GBCGDNIH2_RS04050 6c49ed16faad3a4a0dbb5926e5f960cb 409 PRINTS PR00419 Adrenodoxin reductase family signature 26 39 1.3E-6 T 29-03-2018 GBCGDNIH2_RS04050 6c49ed16faad3a4a0dbb5926e5f960cb 409 PRINTS PR00419 Adrenodoxin reductase family signature 3 25 1.3E-6 T 29-03-2018 GBCGDNIH2_RS04050 6c49ed16faad3a4a0dbb5926e5f960cb 409 Pfam PF03486 HI0933-like protein 4 397 1.5E-100 T 29-03-2018 GBCGDNIH2_RS04050 6c49ed16faad3a4a0dbb5926e5f960cb 409 SUPERFAMILY SSF160996 200 343 1.96E-12 T 29-03-2018 GBCGDNIH2_RS04050 6c49ed16faad3a4a0dbb5926e5f960cb 409 Gene3D G3DSA:3.50.50.60 3 407 4.9E-44 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS01500 87b50a4d66ac183d7d7f4b1926832c39 263 Gene3D G3DSA:3.90.850.10 23 263 1.0E-60 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 GBCGDNIH2_RS01500 87b50a4d66ac183d7d7f4b1926832c39 263 SUPERFAMILY SSF56529 48 255 1.57E-58 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 GBCGDNIH2_RS01500 87b50a4d66ac183d7d7f4b1926832c39 263 Pfam PF10370 Domain of unknown function (DUF2437) 4 51 4.2E-13 T 29-03-2018 IPR018833 Domain of unknown function DUF2437 GBCGDNIH2_RS01500 87b50a4d66ac183d7d7f4b1926832c39 263 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 58 255 3.7E-47 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 GBCGDNIH2_RS07090 e744be03dcc35326e2e9dd96fdc83aae 128 Pfam PF01883 Iron-sulfur cluster assembly protein 32 104 8.4E-21 T 29-03-2018 IPR002744 MIP18 family-like GBCGDNIH2_RS07090 e744be03dcc35326e2e9dd96fdc83aae 128 TIGRFAM TIGR02945 SUF_assoc: FeS assembly SUF system protein 32 128 5.9E-45 T 29-03-2018 IPR014291 SUF system FeS cluster assembly associated GBCGDNIH2_RS07090 e744be03dcc35326e2e9dd96fdc83aae 128 Gene3D G3DSA:3.30.300.130 29 127 1.4E-28 T 29-03-2018 IPR034904 Fe-S cluster assembly domain GBCGDNIH2_RS07090 e744be03dcc35326e2e9dd96fdc83aae 128 SUPERFAMILY SSF117916 29 126 3.27E-33 T 29-03-2018 IPR034904 Fe-S cluster assembly domain GBCGDNIH2_RS07085 a153d94341bd0c3c6e7ab9d6b35e4992 125 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 106 123 - T 29-03-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 GBCGDNIH2_RS07085 a153d94341bd0c3c6e7ab9d6b35e4992 125 Pfam PF01521 Iron-sulphur cluster biosynthesis 22 121 2.9E-19 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 GBCGDNIH2_RS07085 a153d94341bd0c3c6e7ab9d6b35e4992 125 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 22 125 4.5E-32 T 29-03-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 GBCGDNIH2_RS07085 a153d94341bd0c3c6e7ab9d6b35e4992 125 SUPERFAMILY SSF89360 21 114 4.51E-26 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 GBCGDNIH2_RS07085 a153d94341bd0c3c6e7ab9d6b35e4992 125 Gene3D G3DSA:2.60.300.12 20 125 1.8E-34 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 GBCGDNIH2_RS12350 09639ec894805ea8288aa1d101585117 252 Pfam PF06276 Ferric iron reductase FhuF-like transporter 60 200 1.4E-14 T 29-03-2018 IPR022770 Ferric iron reductase FhuF domain GBCGDNIH2_RS12350 09639ec894805ea8288aa1d101585117 252 TIGRFAM TIGR03951 Fe_III_red_FhuF: siderophore-iron reductase FhuF 55 236 1.2E-26 T 29-03-2018 IPR008090 Ferric iron reductase GBCGDNIH2_RS12350 09639ec894805ea8288aa1d101585117 252 Pfam PF11575 FhuF 2Fe-2S C-terminal domain 216 236 2.0E-6 T 29-03-2018 IPR024726 Ferric iron reductase, C-terminal GO:0051537 GBCGDNIH2_RS10590 67b877aa87a77cb92490d5b06644f2e7 234 Gene3D G3DSA:1.10.357.10 18 214 1.4E-15 T 29-03-2018 GBCGDNIH2_RS10590 67b877aa87a77cb92490d5b06644f2e7 234 SUPERFAMILY SSF46689 19 83 3.39E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 GBCGDNIH2_RS10590 67b877aa87a77cb92490d5b06644f2e7 234 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 68 1.3E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GBCGDNIH2_RS10590 67b877aa87a77cb92490d5b06644f2e7 234 ProSitePatterns PS01081 TetR-type HTH domain signature. 37 68 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site GBCGDNIH2_RS10590 67b877aa87a77cb92490d5b06644f2e7 234 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 5.5E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GBCGDNIH2_RS10590 67b877aa87a77cb92490d5b06644f2e7 234 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 5.5E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GBCGDNIH2_RS10590 67b877aa87a77cb92490d5b06644f2e7 234 Pfam PF13972 Bacterial transcriptional repressor 75 225 1.2E-40 T 29-03-2018 IPR025722 Bacterial transcriptional repressor TetR GBCGDNIH2_RS04295 d5125265d9dd22c30fa4fe32d063f937 228 SUPERFAMILY SSF50800 6 228 1.26E-75 T 29-03-2018 IPR011037 Pyruvate kinase-like, insert domain GBCGDNIH2_RS04295 d5125265d9dd22c30fa4fe32d063f937 228 Pfam PF03475 3-alpha domain 174 215 3.1E-14 T 29-03-2018 IPR005163 3-alpha domain GBCGDNIH2_RS04295 d5125265d9dd22c30fa4fe32d063f937 228 Pfam PF03473 MOSC domain 51 163 6.6E-26 T 29-03-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 GBCGDNIH2_RS04295 d5125265d9dd22c30fa4fe32d063f937 228 Gene3D G3DSA:2.40.33.20 1 228 1.5E-53 T 29-03-2018 GBCGDNIH2_RS07765 f89f92bd94ccaa5c72c299451d39f28a 108 Pfam PF12365 Protein of unknown function (DUF3649) 60 86 1.2E-9 T 29-03-2018 IPR022109 Protein of unknown function DUF3649 GBCGDNIH2_RS02390 aaa4a3456131bca02d56c28ae082af70 184 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 22 177 15.209 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 GBCGDNIH2_RS02390 aaa4a3456131bca02d56c28ae082af70 184 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 116 131 1.3E-16 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 GBCGDNIH2_RS02390 aaa4a3456131bca02d56c28ae082af70 184 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 70 78 1.3E-16 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 GBCGDNIH2_RS02390 aaa4a3456131bca02d56c28ae082af70 184 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 152 168 1.3E-16 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 GBCGDNIH2_RS02390 aaa4a3456131bca02d56c28ae082af70 184 Pfam PF01252 Signal peptidase (SPase) II 31 171 3.8E-35 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 GBCGDNIH2_RS02390 aaa4a3456131bca02d56c28ae082af70 184 TIGRFAM TIGR00077 lspA: signal peptidase II 29 175 1.4E-33 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 GBCGDNIH2_RS02390 aaa4a3456131bca02d56c28ae082af70 184 ProSitePatterns PS00855 Signal peptidases II signature. 119 131 - T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 GBCGDNIH2_RS02585 5c4a74059bcf4ba1b130f8e9d75fd528 879 SUPERFAMILY SSF48208 324 370 2.47E-45 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 GBCGDNIH2_RS02585 5c4a74059bcf4ba1b130f8e9d75fd528 879 SUPERFAMILY SSF48208 665 867 2.47E-45 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 GBCGDNIH2_RS02585 5c4a74059bcf4ba1b130f8e9d75fd528 879 SUPERFAMILY SSF48208 419 614 2.47E-45 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 GBCGDNIH2_RS02585 5c4a74059bcf4ba1b130f8e9d75fd528 879 Gene3D G3DSA:1.50.10.10 345 876 7.2E-101 T 29-03-2018 GBCGDNIH2_RS09625 d5f8bc0325aed818ac688792b7a37222 343 Gene3D G3DSA:3.60.110.10 1 337 9.6E-65 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 GBCGDNIH2_RS09625 d5f8bc0325aed818ac688792b7a37222 343 SUPERFAMILY SSF56317 11 275 3.4E-57 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 GBCGDNIH2_RS09625 d5f8bc0325aed818ac688792b7a37222 343 Pfam PF00795 Carbon-nitrogen hydrolase 15 268 4.4E-49 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 GBCGDNIH2_RS02625 656951d0c73b193de175bbcc81264e06 511 SUPERFAMILY SSF56935 128 511 8.33E-28 T 29-03-2018 GBCGDNIH2_RS02625 656951d0c73b193de175bbcc81264e06 511 Gene3D G3DSA:2.40.160.10 81 511 1.9E-30 T 29-03-2018 GBCGDNIH2_RS10570 cbaa48eff0e5f31117c6d07c10308987 160 Pfam PF13436 Glycine-zipper domain 73 115 2.1E-6 T 29-03-2018 IPR025693 Glycine-zipper-containing OmpA-like membrane domain GBCGDNIH2_RS01910 2494c41a3cff51f5796173449ac0d3a3 716 Pfam PF00905 Penicillin binding protein transpeptidase domain 444 707 1.4E-34 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 GBCGDNIH2_RS01910 2494c41a3cff51f5796173449ac0d3a3 716 Gene3D G3DSA:1.10.3810.10 178 375 3.6E-65 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 GBCGDNIH2_RS01910 2494c41a3cff51f5796173449ac0d3a3 716 SUPERFAMILY SSF53955 178 374 1.97E-65 T 29-03-2018 IPR023346 Lysozyme-like domain GBCGDNIH2_RS01910 2494c41a3cff51f5796173449ac0d3a3 716 SUPERFAMILY SSF56601 342 712 2.54E-107 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like GBCGDNIH2_RS01910 2494c41a3cff51f5796173449ac0d3a3 716 Gene3D G3DSA:3.40.710.10 376 715 3.2E-97 T 29-03-2018 GBCGDNIH2_RS01910 2494c41a3cff51f5796173449ac0d3a3 716 Pfam PF00912 Transglycosylase 198 360 3.2E-58 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 GBCGDNIH2_RS01910 2494c41a3cff51f5796173449ac0d3a3 716 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 200 709 3.9E-157 T 29-03-2018 GBCGDNIH2_RS03930 6c60d06413f2c0b7bf6ef370bf0329d8 193 SUPERFAMILY SSF53633 1 144 3.53E-11 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase GBCGDNIH2_RS03930 6c60d06413f2c0b7bf6ef370bf0329d8 193 Gene3D G3DSA:3.40.1160.10 1 154 2.1E-6 T 29-03-2018 GBCGDNIH2_RS03930 6c60d06413f2c0b7bf6ef370bf0329d8 193 Pfam PF00696 Amino acid kinase family 1 145 4.0E-6 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase GBCGDNIH2_RS06675 779f4d9e116197bf29f5fcde44a3e449 321 Pfam PF11306 Protein of unknown function (DUF3108) 82 315 6.0E-30 T 29-03-2018 IPR021457 Protein of unknown function DUF3108 GBCGDNIH2_RS11910 1fde3bae77f664690d10a0632a422a61 400 Gene3D G3DSA:3.40.190.10 143 376 1.2E-29 T 29-03-2018 GBCGDNIH2_RS11910 1fde3bae77f664690d10a0632a422a61 400 Gene3D G3DSA:3.40.190.10 42 142 5.9E-12 T 29-03-2018 GBCGDNIH2_RS11910 1fde3bae77f664690d10a0632a422a61 400 Pfam PF13379 NMT1-like family 41 280 3.9E-49 T 29-03-2018 GBCGDNIH2_RS11910 1fde3bae77f664690d10a0632a422a61 400 SUPERFAMILY SSF53850 43 277 3.38E-40 T 29-03-2018 GBCGDNIH2_RS09135 9f39cc77cdd1df1c014cf8a267fcc63e 252 Pfam PF00106 short chain dehydrogenase 3 183 5.0E-50 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS09135 9f39cc77cdd1df1c014cf8a267fcc63e 252 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 180 0.0034 T 29-03-2018 GBCGDNIH2_RS09135 9f39cc77cdd1df1c014cf8a267fcc63e 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 136 164 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 GBCGDNIH2_RS09135 9f39cc77cdd1df1c014cf8a267fcc63e 252 Gene3D G3DSA:3.40.50.720 1 243 9.5E-55 T 29-03-2018 GBCGDNIH2_RS09135 9f39cc77cdd1df1c014cf8a267fcc63e 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 2.5E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS09135 9f39cc77cdd1df1c014cf8a267fcc63e 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 2.5E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS09135 9f39cc77cdd1df1c014cf8a267fcc63e 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 2.5E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS09135 9f39cc77cdd1df1c014cf8a267fcc63e 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 1.3E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS09135 9f39cc77cdd1df1c014cf8a267fcc63e 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 1.3E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS09135 9f39cc77cdd1df1c014cf8a267fcc63e 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 1.3E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS09135 9f39cc77cdd1df1c014cf8a267fcc63e 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.3E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS09135 9f39cc77cdd1df1c014cf8a267fcc63e 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 1.3E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS09135 9f39cc77cdd1df1c014cf8a267fcc63e 252 SUPERFAMILY SSF51735 3 226 5.82E-60 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS02285 531b777a4be4dd7e15ba5215d73a5033 198 SUPERFAMILY SSF75217 16 157 2.81E-24 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases GBCGDNIH2_RS02285 531b777a4be4dd7e15ba5215d73a5033 198 Gene3D G3DSA:3.40.1280.10 5 170 1.6E-28 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal GBCGDNIH2_RS02285 531b777a4be4dd7e15ba5215d73a5033 198 Pfam PF00588 SpoU rRNA Methylase family 19 150 4.4E-18 T 29-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 GBCGDNIH2_RS02670 f40612a7a7796522c11c0a81a252bda6 536 Pfam PF00999 Sodium/hydrogen exchanger family 6 402 4.3E-55 T 29-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 GBCGDNIH2_RS02995 78982e822333c49787359a92cd85c0e9 231 Pfam PF03548 Outer membrane lipoprotein carrier protein LolA 70 224 2.9E-28 T 29-03-2018 IPR004564 Outer membrane lipoprotein carrier protein LolA-like GBCGDNIH2_RS02995 78982e822333c49787359a92cd85c0e9 231 Gene3D G3DSA:2.50.20.10 56 230 7.1E-24 T 29-03-2018 GBCGDNIH2_RS02995 78982e822333c49787359a92cd85c0e9 231 SUPERFAMILY SSF89392 61 226 7.85E-29 T 29-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX GBCGDNIH2_RS05725 f799ac0eb21eb23bce99d6865b25c028 234 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 6.5E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GBCGDNIH2_RS05725 f799ac0eb21eb23bce99d6865b25c028 234 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 6.5E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GBCGDNIH2_RS05725 f799ac0eb21eb23bce99d6865b25c028 234 Gene3D G3DSA:1.10.10.60 2 61 1.3E-12 T 29-03-2018 GBCGDNIH2_RS05725 f799ac0eb21eb23bce99d6865b25c028 234 SUPERFAMILY SSF46689 7 70 2.24E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 GBCGDNIH2_RS05725 f799ac0eb21eb23bce99d6865b25c028 234 SUPERFAMILY SSF48498 114 181 1.51E-5 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal GBCGDNIH2_RS05725 f799ac0eb21eb23bce99d6865b25c028 234 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 62 2.7E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GBCGDNIH2_RS05725 f799ac0eb21eb23bce99d6865b25c028 234 Gene3D G3DSA:1.10.357.10 62 220 1.6E-8 T 29-03-2018 GBCGDNIH2_RS09290 e314edc842d147044a317dacb4b35689 305 Gene3D G3DSA:1.10.10.10 6 93 1.1E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS09290 e314edc842d147044a317dacb4b35689 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 68 7.4E-21 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS09290 e314edc842d147044a317dacb4b35689 305 Pfam PF03466 LysR substrate binding domain 95 299 6.9E-39 T 29-03-2018 IPR005119 LysR, substrate-binding GBCGDNIH2_RS09290 e314edc842d147044a317dacb4b35689 305 SUPERFAMILY SSF46785 10 118 5.33E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS09290 e314edc842d147044a317dacb4b35689 305 Gene3D G3DSA:3.40.190.10 95 181 9.4E-11 T 29-03-2018 GBCGDNIH2_RS09290 e314edc842d147044a317dacb4b35689 305 SUPERFAMILY SSF53850 96 299 3.8E-41 T 29-03-2018 GBCGDNIH2_RS09290 e314edc842d147044a317dacb4b35689 305 Gene3D G3DSA:3.40.190.10 182 272 3.7E-26 T 29-03-2018 GBCGDNIH2_RS09290 e314edc842d147044a317dacb4b35689 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 25 36 5.5E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS09290 e314edc842d147044a317dacb4b35689 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 57 5.5E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS09290 e314edc842d147044a317dacb4b35689 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 46 5.5E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS03360 5abf9d94f64ec795ddc2260b56f75401 215 Gene3D G3DSA:3.40.50.10230 5 215 5.7E-79 T 29-03-2018 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 GBCGDNIH2_RS03360 5abf9d94f64ec795ddc2260b56f75401 215 Pfam PF02570 Precorrin-8X methylmutase 14 212 2.9E-73 T 29-03-2018 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 GBCGDNIH2_RS03360 5abf9d94f64ec795ddc2260b56f75401 215 SUPERFAMILY SSF63965 5 212 6.15E-72 T 29-03-2018 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 GBCGDNIH2_RS02915 c176d4550010128214ba68198a577e5a 119 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 7 119 1.9E-42 T 29-03-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS02915 c176d4550010128214ba68198a577e5a 119 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 7 119 1.3E-40 T 29-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS02915 c176d4550010128214ba68198a577e5a 119 SUPERFAMILY SSF53137 9 117 6.76E-50 T 29-03-2018 GBCGDNIH2_RS02915 c176d4550010128214ba68198a577e5a 119 Gene3D G3DSA:3.30.420.100 4 119 7.4E-42 T 29-03-2018 GBCGDNIH2_RS02915 c176d4550010128214ba68198a577e5a 119 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 2 119 28.327 T 29-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS02750 eaa8ad64371a32b007da721c32f22893 170 SMART SM00529 69 167 1.6E-25 T 29-03-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 GBCGDNIH2_RS02750 eaa8ad64371a32b007da721c32f22893 170 Gene3D G3DSA:1.10.60.10 108 162 8.0E-19 T 29-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 GBCGDNIH2_RS02750 eaa8ad64371a32b007da721c32f22893 170 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 108 160 2.0E-13 T 29-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 GBCGDNIH2_RS02750 eaa8ad64371a32b007da721c32f22893 170 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 48 104 6.3E-9 T 29-03-2018 IPR022687 DTXR-type HTH domain GO:0003677 GBCGDNIH2_RS02750 eaa8ad64371a32b007da721c32f22893 170 SUPERFAMILY SSF47979 108 163 1.09E-13 T 29-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 GBCGDNIH2_RS02750 eaa8ad64371a32b007da721c32f22893 170 SMART SM00419 65 109 0.0089 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 GBCGDNIH2_RS02750 eaa8ad64371a32b007da721c32f22893 170 SUPERFAMILY SSF46785 61 129 2.73E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS02750 eaa8ad64371a32b007da721c32f22893 170 Gene3D G3DSA:1.10.10.10 37 107 3.8E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS00335 bf8112006659d07a32ede783f6f3b248 268 Gene3D G3DSA:3.90.470.20 152 231 1.4E-5 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 GBCGDNIH2_RS00335 bf8112006659d07a32ede783f6f3b248 268 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 137 202 3.0E-7 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 GBCGDNIH2_RS00335 bf8112006659d07a32ede783f6f3b248 268 SUPERFAMILY SSF56214 49 128 2.49E-20 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 GBCGDNIH2_RS00335 bf8112006659d07a32ede783f6f3b248 268 SUPERFAMILY SSF56214 136 243 4.01E-14 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 GBCGDNIH2_RS00335 bf8112006659d07a32ede783f6f3b248 268 Gene3D G3DSA:3.90.470.20 37 151 7.7E-24 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 GBCGDNIH2_RS03320 927322db0f733ce7343ee4faaf265194 342 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 207 220 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 GBCGDNIH2_RS03320 927322db0f733ce7343ee4faaf265194 342 Pfam PF00155 Aminotransferase class I and II 56 287 4.0E-27 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 GBCGDNIH2_RS03320 927322db0f733ce7343ee4faaf265194 342 TIGRFAM TIGR01140 L_thr_O3P_dcar: threonine-phosphate decarboxylase 15 341 5.8E-91 T 29-03-2018 IPR005860 L-threonine-O-3-phosphate decarboxylase GO:0003824|GO:0009236 KEGG: 00860+4.1.1.81|MetaCyc: PWY-5443 GBCGDNIH2_RS03320 927322db0f733ce7343ee4faaf265194 342 Gene3D G3DSA:3.40.640.10 56 240 4.5E-22 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GBCGDNIH2_RS03320 927322db0f733ce7343ee4faaf265194 342 SUPERFAMILY SSF53383 12 339 6.74E-53 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase GBCGDNIH2_RS03320 927322db0f733ce7343ee4faaf265194 342 Gene3D G3DSA:3.90.1150.10 241 337 8.6E-8 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 GBCGDNIH2_RS00150 a945a1c2ba5d1bb8b149d4b853521db9 278 Gene3D G3DSA:3.40.47.10 22 166 5.0E-8 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 GBCGDNIH2_RS00150 a945a1c2ba5d1bb8b149d4b853521db9 278 Pfam PF13723 Beta-ketoacyl synthase, N-terminal domain 42 206 1.6E-24 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal GBCGDNIH2_RS00150 a945a1c2ba5d1bb8b149d4b853521db9 278 SUPERFAMILY SSF53901 9 159 6.81E-10 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 GBCGDNIH2_RS09015 95a606c3351123f40aa4c193e60b32dc 68 Pfam PF13770 Domain of unknown function (DUF4169) 2 56 1.1E-17 T 29-03-2018 IPR025227 Protein of unknown function DUF4169 GBCGDNIH2_RS05830 f96fac8fbeb220dcb9c5408ca6d5c580 514 SUPERFAMILY SSF47323 351 508 2.43E-37 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 GBCGDNIH2_RS05830 f96fac8fbeb220dcb9c5408ca6d5c580 514 Gene3D G3DSA:3.40.50.620 2 346 2.9E-94 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GBCGDNIH2_RS05830 f96fac8fbeb220dcb9c5408ca6d5c580 514 Pfam PF09334 tRNA synthetases class I (M) 5 363 2.6E-106 T 29-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 GBCGDNIH2_RS05830 f96fac8fbeb220dcb9c5408ca6d5c580 514 PRINTS PR01041 Methionyl-tRNA synthetase signature 7 20 3.0E-33 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 GBCGDNIH2_RS05830 f96fac8fbeb220dcb9c5408ca6d5c580 514 PRINTS PR01041 Methionyl-tRNA synthetase signature 87 98 3.0E-33 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 GBCGDNIH2_RS05830 f96fac8fbeb220dcb9c5408ca6d5c580 514 PRINTS PR01041 Methionyl-tRNA synthetase signature 258 273 3.0E-33 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 GBCGDNIH2_RS05830 f96fac8fbeb220dcb9c5408ca6d5c580 514 PRINTS PR01041 Methionyl-tRNA synthetase signature 350 361 3.0E-33 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 GBCGDNIH2_RS05830 f96fac8fbeb220dcb9c5408ca6d5c580 514 PRINTS PR01041 Methionyl-tRNA synthetase signature 39 53 3.0E-33 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 GBCGDNIH2_RS05830 f96fac8fbeb220dcb9c5408ca6d5c580 514 PRINTS PR01041 Methionyl-tRNA synthetase signature 226 237 3.0E-33 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 GBCGDNIH2_RS05830 f96fac8fbeb220dcb9c5408ca6d5c580 514 Gene3D G3DSA:1.10.730.10 347 511 1.5E-39 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 GBCGDNIH2_RS05830 f96fac8fbeb220dcb9c5408ca6d5c580 514 Hamap MF_01228 Methionine--tRNA ligase [metG]. 1 508 47.031 T 29-03-2018 IPR023457 Methionine-tRNA synthetase, type 2 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 GBCGDNIH2_RS05830 f96fac8fbeb220dcb9c5408ca6d5c580 514 SUPERFAMILY SSF52374 3 348 4.83E-108 T 29-03-2018 GBCGDNIH2_RS05830 f96fac8fbeb220dcb9c5408ca6d5c580 514 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 6 482 3.6E-149 T 29-03-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 GBCGDNIH2_RS03185 0b6046767768dd1256963d4ce6fe3fb3 343 Gene3D G3DSA:3.90.79.10 215 342 3.7E-32 T 29-03-2018 GBCGDNIH2_RS03185 0b6046767768dd1256963d4ce6fe3fb3 343 Pfam PF13302 Acetyltransferase (GNAT) domain 1 153 7.8E-29 T 29-03-2018 IPR000182 GNAT domain GO:0008080 GBCGDNIH2_RS03185 0b6046767768dd1256963d4ce6fe3fb3 343 SUPERFAMILY SSF55811 212 340 3.52E-41 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 GBCGDNIH2_RS03185 0b6046767768dd1256963d4ce6fe3fb3 343 Pfam PF14815 NUDIX domain 220 332 1.5E-21 T 29-03-2018 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 GBCGDNIH2_RS03185 0b6046767768dd1256963d4ce6fe3fb3 343 ProSitePatterns PS00893 Nudix box signature. 249 270 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 GBCGDNIH2_RS03185 0b6046767768dd1256963d4ce6fe3fb3 343 PRINTS PR00502 NUDIX hydrolase family signature 244 258 9.2E-10 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 GBCGDNIH2_RS03185 0b6046767768dd1256963d4ce6fe3fb3 343 PRINTS PR00502 NUDIX hydrolase family signature 258 273 9.2E-10 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 GBCGDNIH2_RS03185 0b6046767768dd1256963d4ce6fe3fb3 343 SUPERFAMILY SSF55729 1 159 4.83E-33 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase GBCGDNIH2_RS03185 0b6046767768dd1256963d4ce6fe3fb3 343 Gene3D G3DSA:3.40.630.30 1 183 1.7E-24 T 29-03-2018 GBCGDNIH2_RS09545 5328cb212284b16e60f4528ac0a2b40b 387 SUPERFAMILY SSF46894 294 359 5.1E-13 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 GBCGDNIH2_RS09545 5328cb212284b16e60f4528ac0a2b40b 387 Pfam PF00196 Bacterial regulatory proteins, luxR family 304 358 1.0E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 GBCGDNIH2_RS09545 5328cb212284b16e60f4528ac0a2b40b 387 Gene3D G3DSA:1.10.10.10 24 361 1.5E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS09545 5328cb212284b16e60f4528ac0a2b40b 387 SMART SM00421 302 359 3.0E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 GBCGDNIH2_RS09000 8f05a68d6e31cd1c8cda0f6194fdc4d4 173 PRINTS PR00502 NUDIX hydrolase family signature 63 78 3.8E-5 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 GBCGDNIH2_RS09000 8f05a68d6e31cd1c8cda0f6194fdc4d4 173 PRINTS PR00502 NUDIX hydrolase family signature 49 63 3.8E-5 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 GBCGDNIH2_RS09000 8f05a68d6e31cd1c8cda0f6194fdc4d4 173 SUPERFAMILY SSF55811 12 166 2.3E-30 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 GBCGDNIH2_RS09000 8f05a68d6e31cd1c8cda0f6194fdc4d4 173 ProSitePatterns PS00893 Nudix box signature. 54 75 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 GBCGDNIH2_RS09000 8f05a68d6e31cd1c8cda0f6194fdc4d4 173 Gene3D G3DSA:3.90.79.10 8 168 6.0E-31 T 29-03-2018 GBCGDNIH2_RS09000 8f05a68d6e31cd1c8cda0f6194fdc4d4 173 Pfam PF00293 NUDIX domain 18 160 2.6E-25 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 GBCGDNIH2_RS09000 8f05a68d6e31cd1c8cda0f6194fdc4d4 173 Hamap MF_00298 RNA pyrophosphohydrolase [rppH]. 12 170 33.327 T 29-03-2018 IPR022927 RNA pyrophosphohydrolase RppH GBCGDNIH2_RS11020 ab665a45d9947a84388858a009bbf2c0 472 SUPERFAMILY SSF103473 36 443 7.46E-30 T 29-03-2018 IPR020846 Major facilitator superfamily domain GBCGDNIH2_RS11020 ab665a45d9947a84388858a009bbf2c0 472 Gene3D G3DSA:1.20.1250.20 256 455 4.3E-15 T 29-03-2018 GBCGDNIH2_RS11020 ab665a45d9947a84388858a009bbf2c0 472 Gene3D G3DSA:1.20.1250.20 33 229 2.2E-12 T 29-03-2018 GBCGDNIH2_RS11020 ab665a45d9947a84388858a009bbf2c0 472 Pfam PF07690 Major Facilitator Superfamily 66 400 1.7E-19 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 GBCGDNIH2_RS04500 159cf8804eec627e4c4be1f75501bb38 132 SUPERFAMILY SSF103088 21 126 4.71E-14 T 29-03-2018 IPR006665 OmpA-like domain GBCGDNIH2_RS04500 159cf8804eec627e4c4be1f75501bb38 132 Gene3D G3DSA:3.30.1330.60 13 128 2.7E-14 T 29-03-2018 IPR006665 OmpA-like domain GBCGDNIH2_RS04500 159cf8804eec627e4c4be1f75501bb38 132 Pfam PF00691 OmpA family 29 106 2.0E-9 T 29-03-2018 IPR006665 OmpA-like domain GBCGDNIH2_RS05895 192d28c050464753a76dcfb778914805 306 PIRSF PIRSF038992 20 303 4.5E-62 T 29-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 GBCGDNIH2_RS05895 192d28c050464753a76dcfb778914805 306 SMART SM01133 40 286 1.4E-50 T 29-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 GBCGDNIH2_RS05895 192d28c050464753a76dcfb778914805 306 Pfam PF01791 DeoC/LacD family aldolase 41 286 3.2E-33 T 29-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 GBCGDNIH2_RS05895 192d28c050464753a76dcfb778914805 306 SUPERFAMILY SSF51569 20 302 3.48E-64 T 29-03-2018 GBCGDNIH2_RS05895 192d28c050464753a76dcfb778914805 306 Gene3D G3DSA:3.20.20.70 24 303 1.3E-63 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS08835 2a529a3c9bf3900ce6bc22fac670bbc5 208 Pfam PF00694 Aconitase C-terminal domain 1 122 8.2E-37 T 29-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 GBCGDNIH2_RS08835 2a529a3c9bf3900ce6bc22fac670bbc5 208 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 186 8.3E-75 T 29-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 GBCGDNIH2_RS08835 2a529a3c9bf3900ce6bc22fac670bbc5 208 SUPERFAMILY SSF52016 1 191 3.14E-58 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel GBCGDNIH2_RS08835 2a529a3c9bf3900ce6bc22fac670bbc5 208 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 200 39.823 T 29-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 GBCGDNIH2_RS08835 2a529a3c9bf3900ce6bc22fac670bbc5 208 Gene3D G3DSA:3.20.19.10 1 174 1.2E-46 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel GBCGDNIH2_RS06275 e837de5f9bb80a40a35ec8d790af87d1 282 SUPERFAMILY SSF53474 17 273 5.99E-38 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS06275 e837de5f9bb80a40a35ec8d790af87d1 282 PRINTS PR00111 Alpha/beta hydrolase fold signature 223 237 2.7E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 GBCGDNIH2_RS06275 e837de5f9bb80a40a35ec8d790af87d1 282 PRINTS PR00111 Alpha/beta hydrolase fold signature 115 128 2.7E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 GBCGDNIH2_RS06275 e837de5f9bb80a40a35ec8d790af87d1 282 PRINTS PR00111 Alpha/beta hydrolase fold signature 70 85 2.7E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 GBCGDNIH2_RS06275 e837de5f9bb80a40a35ec8d790af87d1 282 PRINTS PR00111 Alpha/beta hydrolase fold signature 129 142 2.7E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 GBCGDNIH2_RS06275 e837de5f9bb80a40a35ec8d790af87d1 282 Pfam PF00561 alpha/beta hydrolase fold 45 147 5.4E-11 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 GBCGDNIH2_RS06275 e837de5f9bb80a40a35ec8d790af87d1 282 Gene3D G3DSA:3.40.50.1820 3 277 5.0E-33 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS05470 36a0b099f5797398fe1c1a01780f1c6a 157 Pfam PF04355 SmpA / OmlA family 23 98 8.4E-19 T 29-03-2018 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 GBCGDNIH2_RS05470 36a0b099f5797398fe1c1a01780f1c6a 157 Gene3D G3DSA:3.30.1450.10 24 105 2.1E-5 T 29-03-2018 GBCGDNIH2_RS08540 03aca75b5469f3625266bdc5213789d4 865 Pfam PF01483 Proprotein convertase P-domain 405 477 2.6E-8 T 29-03-2018 IPR002884 Proprotein convertase, P GO:0004252|GO:0006508 GBCGDNIH2_RS08540 03aca75b5469f3625266bdc5213789d4 865 SUPERFAMILY SSF49785 388 501 1.83E-16 T 29-03-2018 IPR008979 Galactose-binding domain-like GBCGDNIH2_RS08540 03aca75b5469f3625266bdc5213789d4 865 Gene3D G3DSA:2.60.120.260 363 504 3.3E-14 T 29-03-2018 IPR008979 Galactose-binding domain-like GBCGDNIH2_RS08540 03aca75b5469f3625266bdc5213789d4 865 Gene3D G3DSA:2.150.10.10 686 861 3.8E-5 T 29-03-2018 GBCGDNIH2_RS08540 03aca75b5469f3625266bdc5213789d4 865 Gene3D G3DSA:2.150.10.10 599 685 2.0E-4 T 29-03-2018 GBCGDNIH2_RS08540 03aca75b5469f3625266bdc5213789d4 865 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 278 288 - T 29-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site GBCGDNIH2_RS08540 03aca75b5469f3625266bdc5213789d4 865 Pfam PF00082 Subtilase family 43 321 5.1E-36 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 GBCGDNIH2_RS08540 03aca75b5469f3625266bdc5213789d4 865 Gene3D G3DSA:3.40.50.200 4 361 3.8E-70 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 GBCGDNIH2_RS08540 03aca75b5469f3625266bdc5213789d4 865 SUPERFAMILY SSF51120 637 860 5.97E-11 T 29-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal GBCGDNIH2_RS08540 03aca75b5469f3625266bdc5213789d4 865 SUPERFAMILY SSF52743 7 359 2.75E-67 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 GBCGDNIH2_RS08540 03aca75b5469f3625266bdc5213789d4 865 PRINTS PR00723 Subtilisin serine protease family (S8) signature 43 62 6.6E-16 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related GBCGDNIH2_RS08540 03aca75b5469f3625266bdc5213789d4 865 PRINTS PR00723 Subtilisin serine protease family (S8) signature 86 99 6.6E-16 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related GBCGDNIH2_RS08540 03aca75b5469f3625266bdc5213789d4 865 PRINTS PR00723 Subtilisin serine protease family (S8) signature 277 293 6.6E-16 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related GBCGDNIH2_RS08540 03aca75b5469f3625266bdc5213789d4 865 SUPERFAMILY SSF51120 568 619 1.46E-7 T 29-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal GBCGDNIH2_RS08540 03aca75b5469f3625266bdc5213789d4 865 SUPERFAMILY SSF51120 247 281 1.46E-7 T 29-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal GBCGDNIH2_RS08540 03aca75b5469f3625266bdc5213789d4 865 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 90 100 - T 29-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site GBCGDNIH2_RS11150 e50631c4058c1b4fda09fc62980dacba 284 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 20 277 1.1E-66 T 29-03-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 GBCGDNIH2_RS11150 e50631c4058c1b4fda09fc62980dacba 284 Gene3D G3DSA:3.40.50.10860 10 126 1.7E-40 T 29-03-2018 GBCGDNIH2_RS11150 e50631c4058c1b4fda09fc62980dacba 284 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 23 105 1.9E-27 T 29-03-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 GBCGDNIH2_RS11150 e50631c4058c1b4fda09fc62980dacba 284 SUPERFAMILY SSF51735 118 279 3.25E-32 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS11150 e50631c4058c1b4fda09fc62980dacba 284 SUPERFAMILY SSF53223 14 117 5.76E-33 T 29-03-2018 GBCGDNIH2_RS11150 e50631c4058c1b4fda09fc62980dacba 284 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 18 283 30.494 T 29-03-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 GBCGDNIH2_RS11150 e50631c4058c1b4fda09fc62980dacba 284 Gene3D G3DSA:3.40.50.720 127 283 5.1E-27 T 29-03-2018 GBCGDNIH2_RS04265 91eee4d676b14fd79534cf17c0bbf7b2 149 Pfam PF00691 OmpA family 51 139 3.3E-16 T 29-03-2018 IPR006665 OmpA-like domain GBCGDNIH2_RS04265 91eee4d676b14fd79534cf17c0bbf7b2 149 SUPERFAMILY SSF103088 49 146 6.93E-26 T 29-03-2018 IPR006665 OmpA-like domain GBCGDNIH2_RS04265 91eee4d676b14fd79534cf17c0bbf7b2 149 ProSitePatterns PS01068 OmpA-like domain. 84 128 - T 29-03-2018 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 GBCGDNIH2_RS04265 91eee4d676b14fd79534cf17c0bbf7b2 149 Gene3D G3DSA:3.30.1330.60 43 149 1.9E-27 T 29-03-2018 IPR006665 OmpA-like domain GBCGDNIH2_RS04265 91eee4d676b14fd79534cf17c0bbf7b2 149 PRINTS PR01021 OMPA domain signature 97 113 1.0E-5 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 GBCGDNIH2_RS04265 91eee4d676b14fd79534cf17c0bbf7b2 149 PRINTS PR01021 OMPA domain signature 82 97 1.0E-5 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 GBCGDNIH2_RS05230 6917f057ab135705de32e1c0db0ef385 394 SUPERFAMILY SSF55031 186 297 5.5E-30 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain GBCGDNIH2_RS05230 6917f057ab135705de32e1c0db0ef385 394 SUPERFAMILY SSF53187 299 383 6.28E-83 T 29-03-2018 GBCGDNIH2_RS05230 6917f057ab135705de32e1c0db0ef385 394 SUPERFAMILY SSF53187 2 198 6.28E-83 T 29-03-2018 GBCGDNIH2_RS05230 6917f057ab135705de32e1c0db0ef385 394 PIRSF PIRSF005962 2 387 4.1E-126 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 GBCGDNIH2_RS05230 6917f057ab135705de32e1c0db0ef385 394 Pfam PF01546 Peptidase family M20/M25/M40 74 381 1.1E-32 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 GBCGDNIH2_RS05230 6917f057ab135705de32e1c0db0ef385 394 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 14 372 7.3E-103 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 GBCGDNIH2_RS05230 6917f057ab135705de32e1c0db0ef385 394 Pfam PF07687 Peptidase dimerisation domain 185 264 2.9E-9 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain GBCGDNIH2_RS05230 6917f057ab135705de32e1c0db0ef385 394 Gene3D G3DSA:3.40.630.10 250 388 1.5E-22 T 29-03-2018 GBCGDNIH2_RS05230 6917f057ab135705de32e1c0db0ef385 394 Gene3D G3DSA:3.40.630.10 2 221 3.8E-49 T 29-03-2018 GBCGDNIH2_RS03530 af116d4a10b949938381c7eb7f260fc4 178 Gene3D G3DSA:3.90.45.10 1 177 1.7E-59 T 29-03-2018 IPR023635 Peptide deformylase GBCGDNIH2_RS03530 af116d4a10b949938381c7eb7f260fc4 178 PIRSF PIRSF004749 1 177 5.6E-54 T 29-03-2018 IPR023635 Peptide deformylase GBCGDNIH2_RS03530 af116d4a10b949938381c7eb7f260fc4 178 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 12 165 7.4E-51 T 29-03-2018 IPR023635 Peptide deformylase GBCGDNIH2_RS03530 af116d4a10b949938381c7eb7f260fc4 178 Hamap MF_00163 Peptide deformylase [def]. 8 171 29.054 T 29-03-2018 IPR023635 Peptide deformylase GBCGDNIH2_RS03530 af116d4a10b949938381c7eb7f260fc4 178 SUPERFAMILY SSF56420 9 173 4.84E-57 T 29-03-2018 IPR023635 Peptide deformylase GBCGDNIH2_RS03530 af116d4a10b949938381c7eb7f260fc4 178 PRINTS PR01576 Peptide deformylase signature 40 69 3.2E-34 T 29-03-2018 IPR023635 Peptide deformylase GBCGDNIH2_RS03530 af116d4a10b949938381c7eb7f260fc4 178 PRINTS PR01576 Peptide deformylase signature 110 128 3.2E-34 T 29-03-2018 IPR023635 Peptide deformylase GBCGDNIH2_RS03530 af116d4a10b949938381c7eb7f260fc4 178 PRINTS PR01576 Peptide deformylase signature 98 109 3.2E-34 T 29-03-2018 IPR023635 Peptide deformylase GBCGDNIH2_RS03530 af116d4a10b949938381c7eb7f260fc4 178 PRINTS PR01576 Peptide deformylase signature 129 158 3.2E-34 T 29-03-2018 IPR023635 Peptide deformylase GBCGDNIH2_RS03530 af116d4a10b949938381c7eb7f260fc4 178 Pfam PF01327 Polypeptide deformylase 11 161 4.6E-50 T 29-03-2018 IPR023635 Peptide deformylase GBCGDNIH2_RS12260 44d3108b7409b35e85d4f3e3d81d58cf 335 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 59 262 2.2E-22 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GBCGDNIH2_RS12260 44d3108b7409b35e85d4f3e3d81d58cf 335 PIRSF PIRSF005917 51 333 6.9E-91 T 29-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 GBCGDNIH2_RS12260 44d3108b7409b35e85d4f3e3d81d58cf 335 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 58 281 33.809 T 29-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 GBCGDNIH2_RS12260 44d3108b7409b35e85d4f3e3d81d58cf 335 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 136 147 - T 29-03-2018 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 GBCGDNIH2_RS12260 44d3108b7409b35e85d4f3e3d81d58cf 335 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 59 328 1.9E-61 T 29-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 GBCGDNIH2_RS12260 44d3108b7409b35e85d4f3e3d81d58cf 335 SUPERFAMILY SSF53790 58 279 7.07E-72 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GBCGDNIH2_RS12260 44d3108b7409b35e85d4f3e3d81d58cf 335 Gene3D G3DSA:3.40.1010.10 57 166 1.0E-36 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GBCGDNIH2_RS12260 44d3108b7409b35e85d4f3e3d81d58cf 335 Gene3D G3DSA:3.30.950.10 167 284 5.1E-33 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GBCGDNIH2_RS06405 72e22d93daf6e3117a9ee3af989c36ac 326 TIGRFAM TIGR00510 lipA: lipoyl synthase 30 314 1.7E-111 T 29-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 GBCGDNIH2_RS06405 72e22d93daf6e3117a9ee3af989c36ac 326 SMART SM00729 81 289 1.6E-12 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 GBCGDNIH2_RS06405 72e22d93daf6e3117a9ee3af989c36ac 326 PIRSF PIRSF005963 5 326 1.3E-132 T 29-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 GBCGDNIH2_RS06405 72e22d93daf6e3117a9ee3af989c36ac 326 SUPERFAMILY SSF102114 46 320 6.54E-63 T 29-03-2018 GBCGDNIH2_RS06405 72e22d93daf6e3117a9ee3af989c36ac 326 Hamap MF_00206 Lipoyl synthase [lipA]. 35 319 144.389 T 29-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 GBCGDNIH2_RS06405 72e22d93daf6e3117a9ee3af989c36ac 326 Gene3D G3DSA:3.20.20.70 39 295 3.3E-25 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS06405 72e22d93daf6e3117a9ee3af989c36ac 326 Pfam PF04055 Radical SAM superfamily 88 247 6.1E-12 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 GBCGDNIH2_RS05440 f976042b5f5bfcf63f4f5c8cb5a0b5a6 386 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 29 219 3.8E-82 T 29-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 GBCGDNIH2_RS05440 f976042b5f5bfcf63f4f5c8cb5a0b5a6 386 PIRSF PIRSF001259 23 384 4.3E-117 T 29-03-2018 GBCGDNIH2_RS05440 f976042b5f5bfcf63f4f5c8cb5a0b5a6 386 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 22 224 38.01 T 29-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 GBCGDNIH2_RS05440 f976042b5f5bfcf63f4f5c8cb5a0b5a6 386 Pfam PF00925 GTP cyclohydrolase II 231 377 2.3E-29 T 29-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 GBCGDNIH2_RS05440 f976042b5f5bfcf63f4f5c8cb5a0b5a6 386 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 28 220 3.7E-72 T 29-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 GBCGDNIH2_RS05440 f976042b5f5bfcf63f4f5c8cb5a0b5a6 386 SUPERFAMILY SSF55821 22 223 1.53E-85 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain GBCGDNIH2_RS05440 f976042b5f5bfcf63f4f5c8cb5a0b5a6 386 Gene3D G3DSA:3.90.870.10 13 233 1.1E-91 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain GBCGDNIH2_RS05440 f976042b5f5bfcf63f4f5c8cb5a0b5a6 386 SUPERFAMILY SSF142695 225 380 3.4E-39 T 29-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 GBCGDNIH2_RS05345 28722c654babcd095a7e6fd125a5d2d8 195 Gene3D G3DSA:3.40.50.1010 4 171 4.8E-33 T 29-03-2018 IPR029060 PIN domain-like GBCGDNIH2_RS05345 28722c654babcd095a7e6fd125a5d2d8 195 Pfam PF01936 NYN domain 8 165 7.8E-39 T 29-03-2018 IPR021139 NYN domain, limkain-b1-type GBCGDNIH2_RS00245 0c3b082bd737f51c27d6b49c4e054c0d 312 Gene3D G3DSA:3.40.50.720 109 284 1.6E-52 T 29-03-2018 GBCGDNIH2_RS00245 0c3b082bd737f51c27d6b49c4e054c0d 312 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 218 234 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site GBCGDNIH2_RS00245 0c3b082bd737f51c27d6b49c4e054c0d 312 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 189 211 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site GBCGDNIH2_RS00245 0c3b082bd737f51c27d6b49c4e054c0d 312 SUPERFAMILY SSF51735 100 282 9.45E-56 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS00245 0c3b082bd737f51c27d6b49c4e054c0d 312 Gene3D G3DSA:3.40.50.720 2 108 1.9E-25 T 29-03-2018 GBCGDNIH2_RS00245 0c3b082bd737f51c27d6b49c4e054c0d 312 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 149 176 - T 29-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 GBCGDNIH2_RS00245 0c3b082bd737f51c27d6b49c4e054c0d 312 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 25 311 1.3E-24 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 GBCGDNIH2_RS00245 0c3b082bd737f51c27d6b49c4e054c0d 312 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 106 281 3.9E-57 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 GBCGDNIH2_RS00245 0c3b082bd737f51c27d6b49c4e054c0d 312 SUPERFAMILY SSF52283 3 135 1.04E-28 T 29-03-2018 GBCGDNIH2_RS00630 28997b4d5800ac1cfe6484614d3accd9 307 SUPERFAMILY SSF161098 93 287 1.83E-17 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GBCGDNIH2_RS00630 28997b4d5800ac1cfe6484614d3accd9 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 303 2.0E-40 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GBCGDNIH2_RS00630 28997b4d5800ac1cfe6484614d3accd9 307 Gene3D G3DSA:1.10.3720.10 4 293 9.7E-40 T 29-03-2018 GBCGDNIH2_RS06950 a3c2bf4954d35f69d6ecf551a8ca97b1 438 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 167 182 - T 29-03-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS06950 a3c2bf4954d35f69d6ecf551a8ca97b1 438 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 344 355 - T 29-03-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS06950 a3c2bf4954d35f69d6ecf551a8ca97b1 438 SUPERFAMILY SSF140490 327 421 4.58E-36 T 29-03-2018 GBCGDNIH2_RS06950 a3c2bf4954d35f69d6ecf551a8ca97b1 438 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 47 217 4.0E-52 T 29-03-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS06950 a3c2bf4954d35f69d6ecf551a8ca97b1 438 SUPERFAMILY SSF142019 3 240 3.14E-88 T 29-03-2018 GBCGDNIH2_RS06950 a3c2bf4954d35f69d6ecf551a8ca97b1 438 SUPERFAMILY SSF142984 241 326 2.35E-24 T 29-03-2018 GBCGDNIH2_RS06950 a3c2bf4954d35f69d6ecf551a8ca97b1 438 Pfam PF10531 SLBB domain 243 292 2.6E-8 T 29-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS06950 a3c2bf4954d35f69d6ecf551a8ca97b1 438 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 333 414 4.7E-30 T 29-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS06950 a3c2bf4954d35f69d6ecf551a8ca97b1 438 SMART SM00928 331 376 1.7E-25 T 29-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS06950 a3c2bf4954d35f69d6ecf551a8ca97b1 438 TIGRFAM TIGR01959 nuoF_fam: NADH oxidoreductase (quinone), F subunit 8 417 1.6E-198 T 29-03-2018 IPR011537 NADH ubiquinone oxidoreductase, F subunit GO:0010181|GO:0016651|GO:0051287|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS06515 d3b6006a53e02c0937f5752b617f3e22 260 SMART SM00382 45 226 2.5E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS06515 d3b6006a53e02c0937f5752b617f3e22 260 SUPERFAMILY SSF52540 21 240 1.92E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS06515 d3b6006a53e02c0937f5752b617f3e22 260 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GBCGDNIH2_RS06515 d3b6006a53e02c0937f5752b617f3e22 260 Pfam PF00005 ABC transporter 37 178 9.3E-24 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GBCGDNIH2_RS06515 d3b6006a53e02c0937f5752b617f3e22 260 Gene3D G3DSA:3.40.50.300 18 258 6.5E-48 T 29-03-2018 GBCGDNIH2_RS03850 bb48642043e232cc541524d2f509ac64 951 SUPERFAMILY SSF51445 523 822 2.65E-135 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily GBCGDNIH2_RS03850 bb48642043e232cc541524d2f509ac64 951 SUPERFAMILY SSF51445 241 493 2.65E-135 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily GBCGDNIH2_RS03850 bb48642043e232cc541524d2f509ac64 951 SUPERFAMILY SSF51445 3 177 2.65E-135 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily GBCGDNIH2_RS03850 bb48642043e232cc541524d2f509ac64 951 Pfam PF00128 Alpha amylase, catalytic domain 24 93 2.2E-15 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 GBCGDNIH2_RS03850 bb48642043e232cc541524d2f509ac64 951 Gene3D G3DSA:3.20.20.80 4 824 1.2E-109 T 29-03-2018 GBCGDNIH2_RS03850 bb48642043e232cc541524d2f509ac64 951 SMART SM00642 15 450 3.1E-6 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 GBCGDNIH2_RS03850 bb48642043e232cc541524d2f509ac64 951 TIGRFAM TIGR02401 trehalose_TreY: malto-oligosyltrehalose synthase 3 868 3.9E-293 T 29-03-2018 IPR012767 Maltooligosyl trehalose synthase KEGG: 00500+5.4.99.15|MetaCyc: PWY-2661 GBCGDNIH2_RS11770 8e35efdfa0aed023b815022b28d99c41 280 SMART SM00971 22 126 1.5E-50 T 29-03-2018 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 GBCGDNIH2_RS11770 8e35efdfa0aed023b815022b28d99c41 280 Pfam PF06426 Serine acetyltransferase, N-terminal 22 126 6.5E-30 T 29-03-2018 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 GBCGDNIH2_RS11770 8e35efdfa0aed023b815022b28d99c41 280 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 207 239 4.7E-9 T 29-03-2018 IPR001451 Hexapeptide repeat GBCGDNIH2_RS11770 8e35efdfa0aed023b815022b28d99c41 280 Gene3D G3DSA:1.10.3130.10 5 152 7.2E-31 T 29-03-2018 GBCGDNIH2_RS11770 8e35efdfa0aed023b815022b28d99c41 280 Gene3D G3DSA:2.160.10.10 153 272 4.0E-28 T 29-03-2018 GBCGDNIH2_RS11770 8e35efdfa0aed023b815022b28d99c41 280 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 97 254 1.3E-68 T 29-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 GBCGDNIH2_RS11770 8e35efdfa0aed023b815022b28d99c41 280 SUPERFAMILY SSF51161 64 271 1.07E-54 T 29-03-2018 IPR011004 Trimeric LpxA-like GBCGDNIH2_RS11770 8e35efdfa0aed023b815022b28d99c41 280 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 215 243 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 GBCGDNIH2_RS02475 7783ac56c9a0602ef87287d61ce7054e 67 Pfam PF01165 Ribosomal protein S21 2 55 1.9E-20 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS02475 7783ac56c9a0602ef87287d61ce7054e 67 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 1 56 1.0E-21 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS02475 7783ac56c9a0602ef87287d61ce7054e 67 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 10 55 12.436 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS02475 7783ac56c9a0602ef87287d61ce7054e 67 Gene3D G3DSA:1.20.5.1150 14 50 2.4E-15 T 29-03-2018 GBCGDNIH2_RS02475 7783ac56c9a0602ef87287d61ce7054e 67 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 13 40 1.0E-8 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS02475 7783ac56c9a0602ef87287d61ce7054e 67 ProSitePatterns PS01181 Ribosomal protein S21 signature. 11 23 - T 29-03-2018 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS09385 1d6c59fbe2297a577fd495616f35b2fe 293 Pfam PF05368 NmrA-like family 7 223 7.9E-14 T 29-03-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 GBCGDNIH2_RS09385 1d6c59fbe2297a577fd495616f35b2fe 293 Gene3D G3DSA:3.40.50.720 7 286 7.5E-21 T 29-03-2018 GBCGDNIH2_RS09385 1d6c59fbe2297a577fd495616f35b2fe 293 SUPERFAMILY SSF51735 7 257 5.57E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS04955 98a2db5b91f0f2603ec0c3df874bad88 348 Gene3D G3DSA:1.10.3720.10 26 334 9.5E-28 T 29-03-2018 GBCGDNIH2_RS04955 98a2db5b91f0f2603ec0c3df874bad88 348 SUPERFAMILY SSF161098 190 332 3.92E-28 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GBCGDNIH2_RS04955 98a2db5b91f0f2603ec0c3df874bad88 348 SUPERFAMILY SSF161098 42 163 3.92E-28 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GBCGDNIH2_RS04955 98a2db5b91f0f2603ec0c3df874bad88 348 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 33 341 2.1E-89 T 29-03-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 GBCGDNIH2_RS04955 98a2db5b91f0f2603ec0c3df874bad88 348 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 336 1.1E-13 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GBCGDNIH2_RS05255 c539a6c5618b15dbd0dd1a1d1b1c8eb8 176 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 89 122 8.4E-5 T 29-03-2018 IPR001451 Hexapeptide repeat GBCGDNIH2_RS05255 c539a6c5618b15dbd0dd1a1d1b1c8eb8 176 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 10 44 6.0E-8 T 29-03-2018 IPR001451 Hexapeptide repeat GBCGDNIH2_RS05255 c539a6c5618b15dbd0dd1a1d1b1c8eb8 176 SUPERFAMILY SSF51161 3 166 1.1E-42 T 29-03-2018 IPR011004 Trimeric LpxA-like GBCGDNIH2_RS05255 c539a6c5618b15dbd0dd1a1d1b1c8eb8 176 Gene3D G3DSA:2.160.10.10 1 175 1.0E-38 T 29-03-2018 GBCGDNIH2_RS12250 cb73f01a9e908c5f1b25a78ca2a20693 503 SUPERFAMILY SSF47384 206 281 7.06E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GBCGDNIH2_RS12250 cb73f01a9e908c5f1b25a78ca2a20693 503 Gene3D G3DSA:1.10.287.130 207 279 9.1E-18 T 29-03-2018 GBCGDNIH2_RS12250 cb73f01a9e908c5f1b25a78ca2a20693 503 Pfam PF00512 His Kinase A (phospho-acceptor) domain 217 281 2.5E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GBCGDNIH2_RS12250 cb73f01a9e908c5f1b25a78ca2a20693 503 SUPERFAMILY SSF55874 272 463 4.19E-43 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS12250 cb73f01a9e908c5f1b25a78ca2a20693 503 PRINTS PR00344 Bacterial sensor protein C-terminal signature 447 460 8.2E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS12250 cb73f01a9e908c5f1b25a78ca2a20693 503 PRINTS PR00344 Bacterial sensor protein C-terminal signature 388 402 8.2E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS12250 cb73f01a9e908c5f1b25a78ca2a20693 503 PRINTS PR00344 Bacterial sensor protein C-terminal signature 406 416 8.2E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS12250 cb73f01a9e908c5f1b25a78ca2a20693 503 PRINTS PR00344 Bacterial sensor protein C-terminal signature 423 441 8.2E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS12250 cb73f01a9e908c5f1b25a78ca2a20693 503 Gene3D G3DSA:3.30.450.20 107 195 0.039 T 29-03-2018 GBCGDNIH2_RS12250 cb73f01a9e908c5f1b25a78ca2a20693 503 SMART SM00387 328 463 2.1E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS12250 cb73f01a9e908c5f1b25a78ca2a20693 503 Gene3D G3DSA:3.30.565.10 288 467 2.1E-42 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS12250 cb73f01a9e908c5f1b25a78ca2a20693 503 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 328 460 1.6E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS12250 cb73f01a9e908c5f1b25a78ca2a20693 503 SMART SM00388 216 283 3.7E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GBCGDNIH2_RS02735 f12977cfcaf64e4b8f3e8bded51f7607 503 SUPERFAMILY SSF51905 153 255 7.92E-22 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS02735 f12977cfcaf64e4b8f3e8bded51f7607 503 SUPERFAMILY SSF51905 314 491 7.92E-22 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS02735 f12977cfcaf64e4b8f3e8bded51f7607 503 SUPERFAMILY SSF51905 21 83 7.92E-22 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS02735 f12977cfcaf64e4b8f3e8bded51f7607 503 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 22 41 8.3E-6 T 29-03-2018 GBCGDNIH2_RS02735 f12977cfcaf64e4b8f3e8bded51f7607 503 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 171 189 8.3E-6 T 29-03-2018 GBCGDNIH2_RS02735 f12977cfcaf64e4b8f3e8bded51f7607 503 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 217 235 8.3E-6 T 29-03-2018 GBCGDNIH2_RS02735 f12977cfcaf64e4b8f3e8bded51f7607 503 Pfam PF13454 FAD-NAD(P)-binding 23 180 7.6E-37 T 29-03-2018 GBCGDNIH2_RS02735 f12977cfcaf64e4b8f3e8bded51f7607 503 Gene3D G3DSA:3.50.50.60 257 499 6.6E-5 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS02735 f12977cfcaf64e4b8f3e8bded51f7607 503 Gene3D G3DSA:3.50.50.60 18 256 4.0E-18 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS10990 14856478cfafd92cb6432e5a22b15b00 229 PIRSF PIRSF006519 1 229 6.5E-74 T 29-03-2018 IPR012061 Glutamate synthase, large subunit domain 3 stand-alone protein GBCGDNIH2_RS10990 14856478cfafd92cb6432e5a22b15b00 229 SUPERFAMILY SSF69336 4 197 8.63E-42 T 29-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 GBCGDNIH2_RS10990 14856478cfafd92cb6432e5a22b15b00 229 Pfam PF01493 GXGXG motif 24 183 2.5E-9 T 29-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 GBCGDNIH2_RS10990 14856478cfafd92cb6432e5a22b15b00 229 Gene3D G3DSA:2.160.20.60 18 198 3.8E-31 T 29-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 GBCGDNIH2_RS08700 fcc6af486a24f00b7740080cb00d7442 428 Gene3D G3DSA:3.30.70.1070 362 422 1.4E-5 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 GBCGDNIH2_RS08700 fcc6af486a24f00b7740080cb00d7442 428 Pfam PF05036 Sporulation related domain 364 413 4.5E-5 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 GBCGDNIH2_RS08700 fcc6af486a24f00b7740080cb00d7442 428 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 60 278 2.5E-59 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 GBCGDNIH2_RS08700 fcc6af486a24f00b7740080cb00d7442 428 SUPERFAMILY SSF56601 35 297 5.41E-75 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like GBCGDNIH2_RS08700 fcc6af486a24f00b7740080cb00d7442 428 Gene3D G3DSA:3.40.710.10 33 313 1.6E-47 T 29-03-2018 GBCGDNIH2_RS08700 fcc6af486a24f00b7740080cb00d7442 428 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 85 96 4.0E-10 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 GBCGDNIH2_RS08700 fcc6af486a24f00b7740080cb00d7442 428 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 138 155 4.0E-10 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 GBCGDNIH2_RS08700 fcc6af486a24f00b7740080cb00d7442 428 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 165 178 4.0E-10 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 GBCGDNIH2_RS01790 054b5761a71fee9b4158ae02e86f6c27 297 TIGRFAM TIGR03870 ABC_MoxJ: methanol oxidation system protein MoxJ 48 293 9.2E-122 T 29-03-2018 IPR022455 Methanol oxidation system protein MoxJ GO:0042597|GO:0046170 GBCGDNIH2_RS01790 054b5761a71fee9b4158ae02e86f6c27 297 SMART SM00062 48 287 1.6E-36 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF GBCGDNIH2_RS01790 054b5761a71fee9b4158ae02e86f6c27 297 Gene3D G3DSA:3.40.190.10 41 143 3.0E-9 T 29-03-2018 GBCGDNIH2_RS01790 054b5761a71fee9b4158ae02e86f6c27 297 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 56 278 1.1E-15 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF GBCGDNIH2_RS01790 054b5761a71fee9b4158ae02e86f6c27 297 Gene3D G3DSA:3.40.190.10 144 241 7.5E-6 T 29-03-2018 GBCGDNIH2_RS01790 054b5761a71fee9b4158ae02e86f6c27 297 SUPERFAMILY SSF53850 46 285 4.03E-22 T 29-03-2018 GBCGDNIH2_RS03955 7f9f49154b645242325099eec462f92f 336 Gene3D G3DSA:3.30.420.40 7 117 3.4E-30 T 29-03-2018 GBCGDNIH2_RS03955 7f9f49154b645242325099eec462f92f 336 SUPERFAMILY SSF53067 116 240 2.69E-8 T 29-03-2018 GBCGDNIH2_RS03955 7f9f49154b645242325099eec462f92f 336 SUPERFAMILY SSF53067 5 77 2.69E-8 T 29-03-2018 GBCGDNIH2_RS03955 7f9f49154b645242325099eec462f92f 336 TIGRFAM TIGR03123 one_C_unchar_1: probable H4MPT-linked C1 transfer pathway protein 8 335 2.3E-97 T 29-03-2018 IPR002756 4-[[4-(2-aminoethyl)phenoxy]-methyl]-2-furanmethanamine-glutamate synthase GBCGDNIH2_RS03955 7f9f49154b645242325099eec462f92f 336 Gene3D G3DSA:3.30.420.190 119 336 2.0E-72 T 29-03-2018 GBCGDNIH2_RS03955 7f9f49154b645242325099eec462f92f 336 Pfam PF01968 Hydantoinase/oxoprolinase 61 240 6.7E-9 T 29-03-2018 IPR002821 Hydantoinase/oxoprolinase GO:0016787 Reactome: R-HSA-174403 GBCGDNIH2_RS06720 bf40a7dfe2f55fe251b95b7558e35687 387 Gene3D G3DSA:3.30.2010.10 181 262 6.0E-16 T 29-03-2018 GBCGDNIH2_RS06720 bf40a7dfe2f55fe251b95b7558e35687 387 Pfam PF01435 Peptidase family M48 192 348 6.8E-22 T 29-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 GBCGDNIH2_RS07130 b10c14e12834fc55f2541ba4ae5eef85 239 SUPERFAMILY SSF49354 30 150 1.44E-16 T 29-03-2018 IPR008962 PapD-like GBCGDNIH2_RS07130 b10c14e12834fc55f2541ba4ae5eef85 239 Gene3D G3DSA:2.60.40.10 34 150 1.8E-22 T 29-03-2018 IPR013783 Immunoglobulin-like fold GBCGDNIH2_RS07130 b10c14e12834fc55f2541ba4ae5eef85 239 Gene3D G3DSA:2.60.40.10 153 226 0.0022 T 29-03-2018 IPR013783 Immunoglobulin-like fold GBCGDNIH2_RS07130 b10c14e12834fc55f2541ba4ae5eef85 239 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 33 150 8.9E-16 T 29-03-2018 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 GBCGDNIH2_RS03230 956ad71ce94b8505acaa89bae3967b9e 343 Gene3D G3DSA:3.40.50.2000 173 341 4.0E-4 T 29-03-2018 GBCGDNIH2_RS03230 956ad71ce94b8505acaa89bae3967b9e 343 Pfam PF06258 Mitochondrial fission ELM1 42 341 7.6E-92 T 29-03-2018 IPR009367 Mitochondrial fission protein ELM1-like GBCGDNIH2_RS03920 ace3fb9058f13cfc66630a3259d9401f 279 SUPERFAMILY SSF56752 5 249 1.83E-56 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 GBCGDNIH2_RS03920 ace3fb9058f13cfc66630a3259d9401f 279 Gene3D G3DSA:3.30.470.10 1 120 3.7E-26 T 29-03-2018 GBCGDNIH2_RS03920 ace3fb9058f13cfc66630a3259d9401f 279 Pfam PF01063 Amino-transferase class IV 32 247 5.2E-43 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 GBCGDNIH2_RS03920 ace3fb9058f13cfc66630a3259d9401f 279 Gene3D G3DSA:3.20.10.10 124 254 3.2E-29 T 29-03-2018 GBCGDNIH2_RS00050 ef4024a5a91f579d3136a4e2fb84ccd6 201 PIRSF PIRSF003078 2 195 4.0E-43 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 GBCGDNIH2_RS00050 ef4024a5a91f579d3136a4e2fb84ccd6 201 SUPERFAMILY SSF53335 9 177 1.34E-28 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GBCGDNIH2_RS00050 ef4024a5a91f579d3136a4e2fb84ccd6 201 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 21 175 3.7E-36 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 GBCGDNIH2_RS00050 ef4024a5a91f579d3136a4e2fb84ccd6 201 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 9 194 24.42 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 GBCGDNIH2_RS00050 ef4024a5a91f579d3136a4e2fb84ccd6 201 Gene3D G3DSA:3.40.50.150 5 190 2.0E-19 T 29-03-2018 GBCGDNIH2_RS00050 ef4024a5a91f579d3136a4e2fb84ccd6 201 Pfam PF02527 rRNA small subunit methyltransferase G 18 178 1.1E-37 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 GBCGDNIH2_RS01855 81e1098bb420afd31fe797be2b04eceb 112 Pfam PF07372 Protein of unknown function (DUF1491) 6 107 6.7E-28 T 29-03-2018 IPR009964 Protein of unknown function DUF1491 GBCGDNIH2_RS04020 b8a78a74fe2f7e3f4b4fe668a9ebffed 268 SUPERFAMILY SSF69336 12 212 9.81E-37 T 29-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 GBCGDNIH2_RS04020 b8a78a74fe2f7e3f4b4fe668a9ebffed 268 Pfam PF01493 GXGXG motif 82 191 1.2E-7 T 29-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 GBCGDNIH2_RS04020 b8a78a74fe2f7e3f4b4fe668a9ebffed 268 Gene3D G3DSA:2.160.20.60 34 136 2.6E-9 T 29-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 GBCGDNIH2_RS04020 b8a78a74fe2f7e3f4b4fe668a9ebffed 268 Gene3D G3DSA:2.160.20.60 137 214 9.0E-15 T 29-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 GBCGDNIH2_RS04020 b8a78a74fe2f7e3f4b4fe668a9ebffed 268 TIGRFAM TIGR03122 one_C_dehyd_C: formylmethanofuran dehydrogenase subunit C 3 264 1.1E-65 T 29-03-2018 IPR017550 Formylmethanofuran dehydrogenase subunit C GO:0015948|GO:0018493|GO:0046914|GO:0055114 KEGG: 00680+1.2.99.5|MetaCyc: PWY-5209|MetaCyc: PWY-7784 GBCGDNIH2_RS09810 af1bc2cf5a560e9a552b3679ce4010ee 321 Gene3D G3DSA:3.40.50.1220 18 309 7.7E-5 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain GBCGDNIH2_RS09810 af1bc2cf5a560e9a552b3679ce4010ee 321 Pfam PF02401 LytB protein 11 293 2.2E-85 T 29-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 GBCGDNIH2_RS09810 af1bc2cf5a560e9a552b3679ce4010ee 321 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 11 295 3.9E-94 T 29-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 GBCGDNIH2_RS09810 af1bc2cf5a560e9a552b3679ce4010ee 321 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 9 297 36.648 T 29-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 GBCGDNIH2_RS06230 e834f0d6421af1d5c75b40acad4007b5 302 Gene3D G3DSA:3.40.50.1820 2 296 4.3E-51 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS06230 e834f0d6421af1d5c75b40acad4007b5 302 SUPERFAMILY SSF53474 1 291 1.49E-65 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS06230 e834f0d6421af1d5c75b40acad4007b5 302 Pfam PF00561 alpha/beta hydrolase fold 23 154 2.4E-16 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 GBCGDNIH2_RS00320 6e18032bae05a89aeab94a96d768edc3 436 Gene3D G3DSA:3.40.50.1480 211 409 4.3E-80 T 29-03-2018 GBCGDNIH2_RS00320 6e18032bae05a89aeab94a96d768edc3 436 SMART SM00997 195 354 1.9E-109 T 29-03-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 GBCGDNIH2_RS00320 6e18032bae05a89aeab94a96d768edc3 436 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 81 95 - T 29-03-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 GBCGDNIH2_RS00320 6e18032bae05a89aeab94a96d768edc3 436 SUPERFAMILY SSF51735 195 354 3.85E-77 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS00320 6e18032bae05a89aeab94a96d768edc3 436 SMART SM00996 9 435 0.0 T 29-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 GBCGDNIH2_RS00320 6e18032bae05a89aeab94a96d768edc3 436 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 10 428 3.5E-187 T 29-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 GBCGDNIH2_RS00320 6e18032bae05a89aeab94a96d768edc3 436 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 9 145 1.6E-72 T 29-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 GBCGDNIH2_RS00320 6e18032bae05a89aeab94a96d768edc3 436 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 195 354 1.9E-80 T 29-03-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 GBCGDNIH2_RS00320 6e18032bae05a89aeab94a96d768edc3 436 Gene3D G3DSA:3.40.50.1480 147 210 4.3E-25 T 29-03-2018 GBCGDNIH2_RS00320 6e18032bae05a89aeab94a96d768edc3 436 Gene3D G3DSA:3.40.50.1480 2 146 7.6E-73 T 29-03-2018 GBCGDNIH2_RS00320 6e18032bae05a89aeab94a96d768edc3 436 SUPERFAMILY SSF52283 355 436 3.46E-118 T 29-03-2018 GBCGDNIH2_RS00320 6e18032bae05a89aeab94a96d768edc3 436 SUPERFAMILY SSF52283 8 194 3.46E-118 T 29-03-2018 GBCGDNIH2_RS00320 6e18032bae05a89aeab94a96d768edc3 436 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 5 428 48.904 T 29-03-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508 GBCGDNIH2_RS00320 6e18032bae05a89aeab94a96d768edc3 436 PIRSF PIRSF001109 1 436 8.4E-195 T 29-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 GBCGDNIH2_RS00320 6e18032bae05a89aeab94a96d768edc3 436 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 217 234 - T 29-03-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 GBCGDNIH2_RS06990 de696989a6643aab83cbfea41a02c338 255 SUPERFAMILY SSF48371 66 251 3.98E-38 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 GBCGDNIH2_RS06990 de696989a6643aab83cbfea41a02c338 255 Pfam PF08713 DNA alkylation repair enzyme 132 226 3.3E-5 T 29-03-2018 IPR014825 DNA alkylation repair enzyme GBCGDNIH2_RS06990 de696989a6643aab83cbfea41a02c338 255 Gene3D G3DSA:1.25.40.290 144 255 2.1E-17 T 29-03-2018 GBCGDNIH2_RS01375 d1d9688acec43f6e5ffe3e56be7512e1 175 Hamap MF_01959 Cytochrome c-type biogenesis protein CcmE [ccmE]. 1 142 32.029 T 29-03-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004 GBCGDNIH2_RS01375 d1d9688acec43f6e5ffe3e56be7512e1 175 SUPERFAMILY SSF82093 29 138 4.71E-36 T 29-03-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004 GBCGDNIH2_RS01375 d1d9688acec43f6e5ffe3e56be7512e1 175 Pfam PF03100 CcmE 4 132 5.2E-42 T 29-03-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004 GBCGDNIH2_RS01375 d1d9688acec43f6e5ffe3e56be7512e1 175 Gene3D G3DSA:2.40.50.140 26 126 4.0E-31 T 29-03-2018 GBCGDNIH2_RS05710 f0d83e96b26d605da44fa2c3efc6fad1 263 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 13 249 5.4E-38 T 29-03-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 GBCGDNIH2_RS05710 f0d83e96b26d605da44fa2c3efc6fad1 263 SUPERFAMILY SSF53213 1 252 5.1E-79 T 29-03-2018 GBCGDNIH2_RS05710 f0d83e96b26d605da44fa2c3efc6fad1 263 PIRSF PIRSF006157 1 263 4.2E-81 T 29-03-2018 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA-type GO:0008270|GO:0016701|GO:0055114 GBCGDNIH2_RS05710 f0d83e96b26d605da44fa2c3efc6fad1 263 Gene3D G3DSA:3.40.830.10 1 263 5.5E-79 T 29-03-2018 GBCGDNIH2_RS00345 ee730ecede5e4560b4d6f7fcc7547abc 234 SUPERFAMILY SSF52317 37 197 1.78E-30 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like GBCGDNIH2_RS00345 ee730ecede5e4560b4d6f7fcc7547abc 234 Pfam PF00117 Glutamine amidotransferase class-I 77 188 1.2E-11 T 29-03-2018 IPR017926 Glutamine amidotransferase GBCGDNIH2_RS00345 ee730ecede5e4560b4d6f7fcc7547abc 234 Gene3D G3DSA:3.40.50.880 32 232 7.6E-26 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like GBCGDNIH2_RS04580 7ab8da858ecd16586d561a5624701f53 245 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 245 31.274 T 29-03-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 GBCGDNIH2_RS04580 7ab8da858ecd16586d561a5624701f53 245 Pfam PF00156 Phosphoribosyl transferase domain 61 163 3.9E-9 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 GBCGDNIH2_RS04580 7ab8da858ecd16586d561a5624701f53 245 Gene3D G3DSA:3.40.50.2020 14 224 6.9E-32 T 29-03-2018 GBCGDNIH2_RS04580 7ab8da858ecd16586d561a5624701f53 245 SUPERFAMILY SSF53271 18 225 6.69E-42 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like GBCGDNIH2_RS10035 42c7144dd42cdae40478279c7914100d 591 SMART SM00564 129 161 1.9E-4 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat GBCGDNIH2_RS10035 42c7144dd42cdae40478279c7914100d 591 SMART SM00564 77 110 59.0 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat GBCGDNIH2_RS10035 42c7144dd42cdae40478279c7914100d 591 SMART SM00564 259 307 180.0 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat GBCGDNIH2_RS10035 42c7144dd42cdae40478279c7914100d 591 SMART SM00564 175 212 0.5 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat GBCGDNIH2_RS10035 42c7144dd42cdae40478279c7914100d 591 SMART SM00564 488 520 4.0E-5 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat GBCGDNIH2_RS10035 42c7144dd42cdae40478279c7914100d 591 SUPERFAMILY SSF50998 26 587 2.88E-175 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily GBCGDNIH2_RS10035 42c7144dd42cdae40478279c7914100d 591 Pfam PF13360 PQQ-like domain 72 216 2.9E-14 T 29-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat GBCGDNIH2_RS10035 42c7144dd42cdae40478279c7914100d 591 ProSitePatterns PS00364 Bacterial quinoprotein dehydrogenases signature 2. 255 276 - T 29-03-2018 IPR001479 Quinoprotein dehydrogenase, conserved site GO:0030288|GO:0055114 GBCGDNIH2_RS10035 42c7144dd42cdae40478279c7914100d 591 Gene3D G3DSA:2.140.10.10 20 591 1.5E-124 T 29-03-2018 GBCGDNIH2_RS10035 42c7144dd42cdae40478279c7914100d 591 TIGRFAM TIGR03075 PQQ_enz_alc_DH: PQQ-dependent dehydrogenase, methanol/ethanol family 16 548 7.3E-226 T 29-03-2018 IPR017512 PQQ-dependent dehydrogenase, methanol/ethanol family GO:0005509|GO:0016020|GO:0016614|GO:0055114 GBCGDNIH2_RS10035 42c7144dd42cdae40478279c7914100d 591 Pfam PF01011 PQQ enzyme repeat 494 526 1.3E-7 T 29-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat GBCGDNIH2_RS05135 ddef57d625f15a9fa4c69acce1db4b7c 170 Pfam PF07977 FabA-like domain 29 153 5.4E-34 T 29-03-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 GBCGDNIH2_RS05135 ddef57d625f15a9fa4c69acce1db4b7c 170 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 20 159 1.4E-55 T 29-03-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 GBCGDNIH2_RS05135 ddef57d625f15a9fa4c69acce1db4b7c 170 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 20 161 34.147 T 29-03-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 GBCGDNIH2_RS05135 ddef57d625f15a9fa4c69acce1db4b7c 170 Gene3D G3DSA:3.10.129.10 2 167 1.0E-54 T 29-03-2018 GBCGDNIH2_RS05135 ddef57d625f15a9fa4c69acce1db4b7c 170 SUPERFAMILY SSF54637 22 163 3.67E-48 T 29-03-2018 IPR029069 HotDog domain GBCGDNIH2_RS01600 58a48f8f9e6226ee10307b03d3e9ea71 439 Pfam PF01546 Peptidase family M20/M25/M40 108 431 1.7E-35 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 GBCGDNIH2_RS01600 58a48f8f9e6226ee10307b03d3e9ea71 439 Pfam PF07687 Peptidase dimerisation domain 240 329 6.4E-6 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain GBCGDNIH2_RS01600 58a48f8f9e6226ee10307b03d3e9ea71 439 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 38 432 8.5E-128 T 29-03-2018 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 GBCGDNIH2_RS01600 58a48f8f9e6226ee10307b03d3e9ea71 439 Gene3D G3DSA:3.40.630.10 271 436 8.7E-22 T 29-03-2018 GBCGDNIH2_RS01600 58a48f8f9e6226ee10307b03d3e9ea71 439 SUPERFAMILY SSF55031 239 350 8.82E-25 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain GBCGDNIH2_RS01600 58a48f8f9e6226ee10307b03d3e9ea71 439 Gene3D G3DSA:3.40.630.10 30 270 1.2E-45 T 29-03-2018 GBCGDNIH2_RS01600 58a48f8f9e6226ee10307b03d3e9ea71 439 PIRSF PIRSF001235 32 438 1.0E-128 T 29-03-2018 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 GBCGDNIH2_RS01600 58a48f8f9e6226ee10307b03d3e9ea71 439 SUPERFAMILY SSF53187 35 248 1.74E-87 T 29-03-2018 GBCGDNIH2_RS01600 58a48f8f9e6226ee10307b03d3e9ea71 439 SUPERFAMILY SSF53187 365 435 1.74E-87 T 29-03-2018 GBCGDNIH2_RS11825 d253557b4d0c31564c0425dce7e54cbe 190 Gene3D G3DSA:3.40.630.30 33 182 1.3E-17 T 29-03-2018 GBCGDNIH2_RS11825 d253557b4d0c31564c0425dce7e54cbe 190 Pfam PF13673 Acetyltransferase (GNAT) domain 64 172 1.1E-7 T 29-03-2018 IPR000182 GNAT domain GO:0008080 GBCGDNIH2_RS11825 d253557b4d0c31564c0425dce7e54cbe 190 SUPERFAMILY SSF55729 34 176 1.58E-19 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase GBCGDNIH2_RS03940 fed1d2bc9af4334c85ee512d829cfc1f 492 SUPERFAMILY SSF51717 127 332 3.14E-28 T 29-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 GBCGDNIH2_RS03940 fed1d2bc9af4334c85ee512d829cfc1f 492 Gene3D G3DSA:3.20.20.20 98 337 2.6E-15 T 29-03-2018 GBCGDNIH2_RS08765 f763addcad364f5307a854380f8c0728 225 Pfam PF06776 Invasion associated locus B (IalB) protein 58 197 4.6E-33 T 29-03-2018 IPR010642 Invasion protein B GBCGDNIH2_RS04680 2f28ea94a873505e3cad2d87fb3cdbef 117 Gene3D G3DSA:1.10.260.40 2 103 1.4E-19 T 29-03-2018 GBCGDNIH2_RS04680 2f28ea94a873505e3cad2d87fb3cdbef 117 SUPERFAMILY SSF47413 5 64 2.12E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GBCGDNIH2_RS04680 2f28ea94a873505e3cad2d87fb3cdbef 117 SMART SM00530 8 63 2.7E-17 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 GBCGDNIH2_RS04680 2f28ea94a873505e3cad2d87fb3cdbef 117 Pfam PF01381 Helix-turn-helix 9 63 9.4E-16 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 GBCGDNIH2_RS12445 31355b27bdfa50b78c3426a6533841b3 279 TIGRFAM TIGR03473 HpnK: hopanoid biosynthesis associated protein HpnK 1 279 1.0E-119 T 29-03-2018 IPR017836 Hopanoid biosynthesis associated protein HpnK GBCGDNIH2_RS12445 31355b27bdfa50b78c3426a6533841b3 279 Pfam PF04794 YdjC-like protein 3 265 1.2E-59 T 29-03-2018 IPR006879 Carbohydrate deacetylase YdjC-like GBCGDNIH2_RS12445 31355b27bdfa50b78c3426a6533841b3 279 Gene3D G3DSA:3.20.20.370 1 279 6.1E-74 T 29-03-2018 GBCGDNIH2_RS12445 31355b27bdfa50b78c3426a6533841b3 279 SUPERFAMILY SSF88713 1 279 2.89E-68 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 GBCGDNIH2_RS07445 72f4341d661b926c42ed812f24de8795 324 Gene3D G3DSA:3.40.50.1100 132 310 5.7E-54 T 29-03-2018 GBCGDNIH2_RS07445 72f4341d661b926c42ed812f24de8795 324 SUPERFAMILY SSF53686 2 318 7.2E-94 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme GBCGDNIH2_RS07445 72f4341d661b926c42ed812f24de8795 324 Gene3D G3DSA:3.40.50.1100 15 131 6.2E-34 T 29-03-2018 GBCGDNIH2_RS07445 72f4341d661b926c42ed812f24de8795 324 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 27 45 - T 29-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 GBCGDNIH2_RS07445 72f4341d661b926c42ed812f24de8795 324 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 3 296 1.5E-67 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme GBCGDNIH2_RS12670 1c118968144f71a46d5d471a27234e03 2656 Pfam PF13403 Hint domain 2452 2587 4.0E-47 T 29-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 GBCGDNIH2_RS12670 1c118968144f71a46d5d471a27234e03 2656 Gene3D G3DSA:2.170.16.10 2445 2648 1.3E-18 T 29-03-2018 GBCGDNIH2_RS12670 1c118968144f71a46d5d471a27234e03 2656 SMART SM00710 433 456 1800.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat GBCGDNIH2_RS12670 1c118968144f71a46d5d471a27234e03 2656 SMART SM00710 1033 1055 9500.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat GBCGDNIH2_RS12670 1c118968144f71a46d5d471a27234e03 2656 SMART SM00710 1579 1615 4100.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat GBCGDNIH2_RS12670 1c118968144f71a46d5d471a27234e03 2656 SMART SM00710 263 285 4400.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat GBCGDNIH2_RS12670 1c118968144f71a46d5d471a27234e03 2656 SMART SM00710 1544 1565 2500.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat GBCGDNIH2_RS12670 1c118968144f71a46d5d471a27234e03 2656 SMART SM00710 1781 1802 2100.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat GBCGDNIH2_RS12670 1c118968144f71a46d5d471a27234e03 2656 SMART SM00710 1169 1191 7000.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat GBCGDNIH2_RS12670 1c118968144f71a46d5d471a27234e03 2656 SMART SM00710 1410 1431 2200.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat GBCGDNIH2_RS12670 1c118968144f71a46d5d471a27234e03 2656 SMART SM00710 219 240 990.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat GBCGDNIH2_RS12670 1c118968144f71a46d5d471a27234e03 2656 SUPERFAMILY SSF51294 2453 2586 8.83E-15 T 29-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 GBCGDNIH2_RS06930 815fee957072198d6db81291bc3d9259 247 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 18 165 7.6E-38 T 29-03-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS00965 5212c3d6974dd08b65b1d16c7060fd2d 222 SUPERFAMILY SSF159594 44 214 8.89E-28 T 29-03-2018 GBCGDNIH2_RS00965 5212c3d6974dd08b65b1d16c7060fd2d 222 Gene3D G3DSA:3.40.50.10610 34 219 6.7E-38 T 29-03-2018 IPR005586 ABC-type transport auxiliary lipoprotein component GBCGDNIH2_RS00965 5212c3d6974dd08b65b1d16c7060fd2d 222 Pfam PF03886 ABC-type transport auxiliary lipoprotein component 50 207 2.0E-40 T 29-03-2018 IPR005586 ABC-type transport auxiliary lipoprotein component GBCGDNIH2_RS05545 7b72a0f8c89df7bc92ab1213dca730ae 282 SUPERFAMILY SSF63380 29 124 6.63E-23 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 GBCGDNIH2_RS05545 7b72a0f8c89df7bc92ab1213dca730ae 282 Gene3D G3DSA:3.40.50.80 122 282 9.6E-19 T 29-03-2018 GBCGDNIH2_RS05545 7b72a0f8c89df7bc92ab1213dca730ae 282 Pfam PF00970 Oxidoreductase FAD-binding domain 38 116 1.2E-6 T 29-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 GBCGDNIH2_RS05545 7b72a0f8c89df7bc92ab1213dca730ae 282 Pfam PF00175 Oxidoreductase NAD-binding domain 137 254 9.2E-8 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 GBCGDNIH2_RS05545 7b72a0f8c89df7bc92ab1213dca730ae 282 SUPERFAMILY SSF52343 128 278 3.4E-37 T 29-03-2018 GBCGDNIH2_RS05545 7b72a0f8c89df7bc92ab1213dca730ae 282 Gene3D G3DSA:2.40.30.10 24 121 7.2E-16 T 29-03-2018 GBCGDNIH2_RS02975 cc14917e73dfe708ec71c1e9301237f5 335 Gene3D G3DSA:3.30.2350.10 91 325 3.5E-61 T 29-03-2018 GBCGDNIH2_RS02975 cc14917e73dfe708ec71c1e9301237f5 335 Pfam PF00849 RNA pseudouridylate synthase 100 253 3.9E-34 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 GBCGDNIH2_RS02975 cc14917e73dfe708ec71c1e9301237f5 335 SMART SM00363 15 74 4.9E-5 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 GBCGDNIH2_RS02975 cc14917e73dfe708ec71c1e9301237f5 335 SUPERFAMILY SSF55120 90 325 7.52E-58 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 GBCGDNIH2_RS02975 cc14917e73dfe708ec71c1e9301237f5 335 Gene3D G3DSA:3.10.290.10 2 74 4.6E-13 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 GBCGDNIH2_RS02975 cc14917e73dfe708ec71c1e9301237f5 335 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 140 154 - T 29-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 GBCGDNIH2_RS02975 cc14917e73dfe708ec71c1e9301237f5 335 SUPERFAMILY SSF55174 14 73 1.33E-7 T 29-03-2018 GBCGDNIH2_RS08945 081d60829fc2c3a1b41a1931a34bf373 89 SUPERFAMILY SSF110324 2 82 1.22E-31 T 29-03-2018 GBCGDNIH2_RS08945 081d60829fc2c3a1b41a1931a34bf373 89 Gene3D G3DSA:2.40.50.100 20 84 1.3E-27 T 29-03-2018 GBCGDNIH2_RS08945 081d60829fc2c3a1b41a1931a34bf373 89 Pfam PF01016 Ribosomal L27 protein 2 79 5.6E-35 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS08945 081d60829fc2c3a1b41a1931a34bf373 89 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 29-03-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS08945 081d60829fc2c3a1b41a1931a34bf373 89 PRINTS PR00063 Ribosomal protein L27 signature 29 53 2.5E-35 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS08945 081d60829fc2c3a1b41a1931a34bf373 89 PRINTS PR00063 Ribosomal protein L27 signature 4 28 2.5E-35 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS08945 081d60829fc2c3a1b41a1931a34bf373 89 PRINTS PR00063 Ribosomal protein L27 signature 54 78 2.5E-35 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS08945 081d60829fc2c3a1b41a1931a34bf373 89 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 69 5.0E-15 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS08945 081d60829fc2c3a1b41a1931a34bf373 89 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 81 9.5E-36 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS08945 081d60829fc2c3a1b41a1931a34bf373 89 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 84 27.509 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS09270 40a01d8391fecc3388e00d89a26da040 384 Gene3D G3DSA:1.10.287.70 167 290 5.6E-12 T 29-03-2018 GBCGDNIH2_RS09270 40a01d8391fecc3388e00d89a26da040 384 SUPERFAMILY SSF53850 25 161 2.93E-37 T 29-03-2018 GBCGDNIH2_RS09270 40a01d8391fecc3388e00d89a26da040 384 SUPERFAMILY SSF53850 274 381 2.93E-37 T 29-03-2018 GBCGDNIH2_RS09270 40a01d8391fecc3388e00d89a26da040 384 Gene3D G3DSA:3.40.190.10 42 166 3.2E-17 T 29-03-2018 GBCGDNIH2_RS09270 40a01d8391fecc3388e00d89a26da040 384 SMART SM00079 54 383 1.0E-4 T 29-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 GBCGDNIH2_RS09270 40a01d8391fecc3388e00d89a26da040 384 Gene3D G3DSA:3.40.190.10 291 384 7.7E-9 T 29-03-2018 GBCGDNIH2_RS09270 40a01d8391fecc3388e00d89a26da040 384 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 63 382 2.3E-33 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF GBCGDNIH2_RS09270 40a01d8391fecc3388e00d89a26da040 384 SUPERFAMILY SSF81324 133 255 1.05E-8 T 29-03-2018 GBCGDNIH2_RS02460 7745a6930c490ee82005c95e9a1a2156 106 Gene3D G3DSA:3.30.70.100 1 106 1.2E-25 T 29-03-2018 GBCGDNIH2_RS02460 7745a6930c490ee82005c95e9a1a2156 106 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 78 1.3E-18 T 29-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain GBCGDNIH2_RS02460 7745a6930c490ee82005c95e9a1a2156 106 SUPERFAMILY SSF54909 1 101 3.41E-33 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel GBCGDNIH2_RS06125 f2f0724aa33c7b6098c442cce790a97f 119 Pfam PF00072 Response regulator receiver domain 5 114 1.1E-5 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GBCGDNIH2_RS06125 f2f0724aa33c7b6098c442cce790a97f 119 Gene3D G3DSA:3.40.50.2300 2 119 4.1E-13 T 29-03-2018 GBCGDNIH2_RS06125 f2f0724aa33c7b6098c442cce790a97f 119 SUPERFAMILY SSF52172 5 119 9.25E-16 T 29-03-2018 IPR011006 CheY-like superfamily GBCGDNIH2_RS09455 df2f7b309b50eff85d3c5f2e660613be 211 SUPERFAMILY SSF50486 15 201 3.61E-60 T 29-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 GBCGDNIH2_RS09455 df2f7b309b50eff85d3c5f2e660613be 211 Gene3D G3DSA:3.10.300.10 11 204 5.3E-63 T 29-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 GBCGDNIH2_RS09455 df2f7b309b50eff85d3c5f2e660613be 211 TIGRFAM TIGR00567 3mg: DNA-3-methyladenine glycosylase 18 197 2.0E-45 T 29-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 GBCGDNIH2_RS09455 df2f7b309b50eff85d3c5f2e660613be 211 Hamap MF_00527 Putative 3-methyladenine DNA glycosylase. 17 197 29.253 T 29-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 GBCGDNIH2_RS09455 df2f7b309b50eff85d3c5f2e660613be 211 Pfam PF02245 Methylpurine-DNA glycosylase (MPG) 19 192 4.8E-58 T 29-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 GBCGDNIH2_RS10170 232dabb10c1386594e3ce175fb928048 411 Gene3D G3DSA:3.40.640.10 180 305 1.3E-42 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GBCGDNIH2_RS10170 232dabb10c1386594e3ce175fb928048 411 SUPERFAMILY SSF53383 24 409 3.2E-120 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase GBCGDNIH2_RS10170 232dabb10c1386594e3ce175fb928048 411 Pfam PF00202 Aminotransferase class-III 26 409 3.5E-122 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 GBCGDNIH2_RS10170 232dabb10c1386594e3ce175fb928048 411 Gene3D G3DSA:3.90.1150.10 306 411 2.4E-27 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 GBCGDNIH2_RS10170 232dabb10c1386594e3ce175fb928048 411 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 234 271 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 GBCGDNIH2_RS10170 232dabb10c1386594e3ce175fb928048 411 TIGRFAM TIGR01885 Orn_aminotrans: ornithine--oxo-acid transaminase 16 408 1.6E-164 T 29-03-2018 IPR010164 Ornithine aminotransferase GO:0004587 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922|Reactome: R-HSA-70614 GBCGDNIH2_RS10170 232dabb10c1386594e3ce175fb928048 411 PIRSF PIRSF000521 22 170 1.4E-8 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 GBCGDNIH2_RS10170 232dabb10c1386594e3ce175fb928048 411 PIRSF PIRSF000521 187 411 1.9E-33 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 GBCGDNIH2_RS10170 232dabb10c1386594e3ce175fb928048 411 Gene3D G3DSA:3.90.1150.10 10 175 6.4E-42 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 GBCGDNIH2_RS00005 95fd3c9fe57c5ac99a56a7c3988f92e7 520 SUPERFAMILY SSF103473 60 251 4.71E-60 T 29-03-2018 IPR020846 Major facilitator superfamily domain GBCGDNIH2_RS00005 95fd3c9fe57c5ac99a56a7c3988f92e7 520 SUPERFAMILY SSF103473 302 508 4.71E-60 T 29-03-2018 IPR020846 Major facilitator superfamily domain GBCGDNIH2_RS00005 95fd3c9fe57c5ac99a56a7c3988f92e7 520 Gene3D G3DSA:1.20.1250.20 55 247 1.9E-31 T 29-03-2018 GBCGDNIH2_RS00005 95fd3c9fe57c5ac99a56a7c3988f92e7 520 Gene3D G3DSA:1.20.1250.20 307 513 1.7E-18 T 29-03-2018 GBCGDNIH2_RS00005 95fd3c9fe57c5ac99a56a7c3988f92e7 520 Pfam PF07690 Major Facilitator Superfamily 68 457 9.1E-49 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 GBCGDNIH2_RS06305 d484ca6a780719144e60ffc793764782 153 Gene3D G3DSA:2.40.30.70 4 150 2.3E-34 T 29-03-2018 IPR023370 TsaA-like domain GBCGDNIH2_RS06305 d484ca6a780719144e60ffc793764782 153 Pfam PF01980 Uncharacterised protein family UPF0066 25 132 7.1E-26 T 29-03-2018 IPR023370 TsaA-like domain GBCGDNIH2_RS06305 d484ca6a780719144e60ffc793764782 153 SUPERFAMILY SSF118196 1 153 2.88E-42 T 29-03-2018 IPR023370 TsaA-like domain GBCGDNIH2_RS01495 e081f7c283aeee4923abd66600a7440b 153 TIGRFAM TIGR03139 QueF-II: 7-cyano-7-deazaguanine reductase 23 132 6.1E-45 T 29-03-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 GBCGDNIH2_RS01495 e081f7c283aeee4923abd66600a7440b 153 Gene3D G3DSA:3.30.1130.10 7 138 3.4E-30 T 29-03-2018 GBCGDNIH2_RS01495 e081f7c283aeee4923abd66600a7440b 153 Hamap MF_00818 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 153 65.707 T 29-03-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 GBCGDNIH2_RS01495 e081f7c283aeee4923abd66600a7440b 153 SUPERFAMILY SSF55620 23 134 3.19E-25 T 29-03-2018 GBCGDNIH2_RS01495 e081f7c283aeee4923abd66600a7440b 153 PIRSF PIRSF027377 4 138 9.4E-51 T 29-03-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 GBCGDNIH2_RS01495 e081f7c283aeee4923abd66600a7440b 153 Pfam PF14489 QueF-like protein 57 135 6.4E-32 T 29-03-2018 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 GBCGDNIH2_RS04025 150238cf84293ae0c70f2ede9712d124 458 SUPERFAMILY SSF54368 21 126 1.31E-9 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 GBCGDNIH2_RS04025 150238cf84293ae0c70f2ede9712d124 458 Pfam PF00120 Glutamine synthetase, catalytic domain 128 454 1.2E-64 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 GBCGDNIH2_RS04025 150238cf84293ae0c70f2ede9712d124 458 SUPERFAMILY SSF55931 127 456 3.04E-76 T 29-03-2018 GBCGDNIH2_RS04025 150238cf84293ae0c70f2ede9712d124 458 Gene3D G3DSA:3.10.20.70 15 126 8.9E-13 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 GBCGDNIH2_RS04025 150238cf84293ae0c70f2ede9712d124 458 Gene3D G3DSA:3.30.590.10 127 458 1.1E-74 T 29-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 GBCGDNIH2_RS04025 150238cf84293ae0c70f2ede9712d124 458 SMART SM01230 127 381 1.7E-72 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 GBCGDNIH2_RS09125 00214f4c1bfeb7827f8dc242378aa67c 434 Pfam PF07642 Putative beta-barrel porin-2, OmpL-like. bbp2 55 434 2.2E-76 T 29-03-2018 IPR011486 Putative beta-barrel porin-2, OmpL-like. bbp2 GBCGDNIH2_RS04950 dda77a1de4ccb8b95cacdbcaeb472039 347 PIRSF PIRSF002756 6 338 1.3E-101 T 29-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 GBCGDNIH2_RS04950 dda77a1de4ccb8b95cacdbcaeb472039 347 Pfam PF12849 PBP superfamily domain 24 305 3.7E-53 T 29-03-2018 IPR024370 PBP domain GBCGDNIH2_RS04950 dda77a1de4ccb8b95cacdbcaeb472039 347 Gene3D G3DSA:3.40.190.10 158 339 1.3E-25 T 29-03-2018 GBCGDNIH2_RS04950 dda77a1de4ccb8b95cacdbcaeb472039 347 Gene3D G3DSA:3.40.190.10 25 157 1.6E-26 T 29-03-2018 GBCGDNIH2_RS04950 dda77a1de4ccb8b95cacdbcaeb472039 347 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 29 335 8.4E-109 T 29-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 GBCGDNIH2_RS04950 dda77a1de4ccb8b95cacdbcaeb472039 347 SUPERFAMILY SSF53850 28 335 1.02E-86 T 29-03-2018 GBCGDNIH2_RS00730 ff35452de4d603fa3120a7565ec9d72f 87 Pfam PF04226 Transglycosylase associated protein 34 80 1.9E-13 T 29-03-2018 IPR007341 Transglycosylase-associated protein GO:0016021 GBCGDNIH2_RS07860 0f317369c0b668c953f462d7924f55a1 339 PIRSF PIRSF000116 4 206 5.1E-44 T 29-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 GBCGDNIH2_RS07860 0f317369c0b668c953f462d7924f55a1 339 PIRSF PIRSF000116 202 331 3.2E-17 T 29-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 GBCGDNIH2_RS07860 0f317369c0b668c953f462d7924f55a1 339 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 14 327 4.0E-130 T 29-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 GBCGDNIH2_RS07860 0f317369c0b668c953f462d7924f55a1 339 SUPERFAMILY SSF48179 184 333 2.04E-71 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 GBCGDNIH2_RS07860 0f317369c0b668c953f462d7924f55a1 339 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 184 327 3.4E-66 T 29-03-2018 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 GBCGDNIH2_RS07860 0f317369c0b668c953f462d7924f55a1 339 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 1 329 45.873 T 29-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 GBCGDNIH2_RS07860 0f317369c0b668c953f462d7924f55a1 339 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 14 178 5.5E-73 T 29-03-2018 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 GBCGDNIH2_RS07860 0f317369c0b668c953f462d7924f55a1 339 Gene3D G3DSA:1.10.1040.10 58 331 2.0E-116 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 GBCGDNIH2_RS07860 0f317369c0b668c953f462d7924f55a1 339 SUPERFAMILY SSF51735 1 183 1.09E-73 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS08060 4c66f883d3c1cd2bbf0be35944ae2adc 681 Gene3D G3DSA:3.40.50.300 236 424 2.3E-9 T 29-03-2018 GBCGDNIH2_RS08060 4c66f883d3c1cd2bbf0be35944ae2adc 681 Pfam PF09373 Pseudomurein-binding repeat 627 654 1.1E-5 T 29-03-2018 IPR018975 Pseudomurein-binding repeat GBCGDNIH2_RS08060 4c66f883d3c1cd2bbf0be35944ae2adc 681 SUPERFAMILY SSF52540 306 385 2.55E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS08060 4c66f883d3c1cd2bbf0be35944ae2adc 681 SUPERFAMILY SSF52540 36 197 2.55E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS08060 4c66f883d3c1cd2bbf0be35944ae2adc 681 SUPERFAMILY SSF52540 225 275 2.55E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS08060 4c66f883d3c1cd2bbf0be35944ae2adc 681 Gene3D G3DSA:3.40.50.300 7 201 2.7E-13 T 29-03-2018 GBCGDNIH2_RS00165 d6aeb7537e68f3ef27d1feab3f0ae995 447 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 49 64 - T 29-03-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site GBCGDNIH2_RS00165 d6aeb7537e68f3ef27d1feab3f0ae995 447 SUPERFAMILY SSF118215 22 415 2.09E-114 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GBCGDNIH2_RS00165 d6aeb7537e68f3ef27d1feab3f0ae995 447 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 308 331 - T 29-03-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site GBCGDNIH2_RS00165 d6aeb7537e68f3ef27d1feab3f0ae995 447 PRINTS PR00173 Glutamate-aspartate symporter signature 87 112 3.9E-24 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GBCGDNIH2_RS00165 d6aeb7537e68f3ef27d1feab3f0ae995 447 PRINTS PR00173 Glutamate-aspartate symporter signature 305 331 3.9E-24 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GBCGDNIH2_RS00165 d6aeb7537e68f3ef27d1feab3f0ae995 447 PRINTS PR00173 Glutamate-aspartate symporter signature 20 40 3.9E-24 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GBCGDNIH2_RS00165 d6aeb7537e68f3ef27d1feab3f0ae995 447 PRINTS PR00173 Glutamate-aspartate symporter signature 158 180 3.9E-24 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GBCGDNIH2_RS00165 d6aeb7537e68f3ef27d1feab3f0ae995 447 PRINTS PR00173 Glutamate-aspartate symporter signature 340 359 3.9E-24 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GBCGDNIH2_RS00165 d6aeb7537e68f3ef27d1feab3f0ae995 447 Gene3D G3DSA:1.10.3860.10 17 421 6.1E-114 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GBCGDNIH2_RS00165 d6aeb7537e68f3ef27d1feab3f0ae995 447 Pfam PF00375 Sodium:dicarboxylate symporter family 22 414 6.1E-105 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GBCGDNIH2_RS00165 d6aeb7537e68f3ef27d1feab3f0ae995 447 Hamap MF_01300 C4-dicarboxylate transport protein [dctA]. 15 441 36.463 T 29-03-2018 IPR023954 C4-dicarboxylate transport protein GO:0006835|GO:0015293|GO:0016021 GBCGDNIH2_RS05485 fe977b8f7fe91565e8fa253f7660eb43 368 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 17 345 2.5E-96 T 29-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 GBCGDNIH2_RS05485 fe977b8f7fe91565e8fa253f7660eb43 368 Pfam PF02504 Fatty acid synthesis protein 16 333 4.0E-103 T 29-03-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 GBCGDNIH2_RS05485 fe977b8f7fe91565e8fa253f7660eb43 368 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 350 132.356 T 29-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 GBCGDNIH2_RS05485 fe977b8f7fe91565e8fa253f7660eb43 368 SUPERFAMILY SSF53659 16 345 5.76E-96 T 29-03-2018 GBCGDNIH2_RS05485 fe977b8f7fe91565e8fa253f7660eb43 368 Gene3D G3DSA:3.40.718.10 12 347 4.3E-99 T 29-03-2018 GBCGDNIH2_RS05485 fe977b8f7fe91565e8fa253f7660eb43 368 PIRSF PIRSF002465 13 349 2.5E-115 T 29-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 GBCGDNIH2_RS07570 461378ce18650882978ab2497af6a192 163 Pfam PF06146 Phosphate-starvation-inducible E 76 146 6.7E-15 T 29-03-2018 IPR020948 Phosphate-starvation-induced PsiE-like GBCGDNIH2_RS01940 81acb5cd4cf7e588185a02a1be09bfe1 212 SUPERFAMILY SSF55144 37 211 8.2E-39 T 29-03-2018 IPR009097 Cyclic phosphodiesterase GBCGDNIH2_RS01940 81acb5cd4cf7e588185a02a1be09bfe1 212 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 37 211 3.3E-42 T 29-03-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 GBCGDNIH2_RS01940 81acb5cd4cf7e588185a02a1be09bfe1 212 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 37 211 23.073 T 29-03-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 GBCGDNIH2_RS01940 81acb5cd4cf7e588185a02a1be09bfe1 212 Pfam PF13563 2'-5' RNA ligase superfamily 70 177 5.3E-13 T 29-03-2018 GBCGDNIH2_RS01940 81acb5cd4cf7e588185a02a1be09bfe1 212 Gene3D G3DSA:3.90.1140.10 33 212 6.4E-31 T 29-03-2018 GBCGDNIH2_RS06905 0d1519515adc511a9ede7690bd546dff 261 Gene3D G3DSA:2.30.30.100 209 253 1.1E-7 T 29-03-2018 GBCGDNIH2_RS06905 0d1519515adc511a9ede7690bd546dff 261 Gene3D G3DSA:3.30.930.10 5 208 7.4E-43 T 29-03-2018 GBCGDNIH2_RS06905 0d1519515adc511a9ede7690bd546dff 261 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 18 253 9.3E-37 T 29-03-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 GBCGDNIH2_RS06905 0d1519515adc511a9ede7690bd546dff 261 Pfam PF03099 Biotin/lipoate A/B protein ligase family 24 151 3.5E-10 T 29-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 GBCGDNIH2_RS06905 0d1519515adc511a9ede7690bd546dff 261 Pfam PF02237 Biotin protein ligase C terminal domain 219 253 1.5E-4 T 29-03-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 GBCGDNIH2_RS06905 0d1519515adc511a9ede7690bd546dff 261 SUPERFAMILY SSF50037 211 253 4.12E-5 T 29-03-2018 IPR008988 Transcriptional repressor, C-terminal GBCGDNIH2_RS06905 0d1519515adc511a9ede7690bd546dff 261 SUPERFAMILY SSF55681 10 204 1.99E-36 T 29-03-2018 GBCGDNIH2_RS05425 e60881dd2aead5c90c044fa18358967a 312 Gene3D G3DSA:3.30.1330.10 1 135 6.5E-25 T 29-03-2018 IPR016188 PurM-like, N-terminal domain GBCGDNIH2_RS05425 e60881dd2aead5c90c044fa18358967a 312 PIRSF PIRSF005303 4 312 3.6E-71 T 29-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 GBCGDNIH2_RS05425 e60881dd2aead5c90c044fa18358967a 312 Pfam PF00586 AIR synthase related protein, N-terminal domain 19 132 5.5E-18 T 29-03-2018 IPR016188 PurM-like, N-terminal domain GBCGDNIH2_RS05425 e60881dd2aead5c90c044fa18358967a 312 SUPERFAMILY SSF56042 136 287 2.69E-29 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain GBCGDNIH2_RS05425 e60881dd2aead5c90c044fa18358967a 312 Pfam PF02769 AIR synthase related protein, C-terminal domain 145 289 1.2E-8 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain GBCGDNIH2_RS05425 e60881dd2aead5c90c044fa18358967a 312 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 15 312 3.1E-81 T 29-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 GBCGDNIH2_RS05425 e60881dd2aead5c90c044fa18358967a 312 SUPERFAMILY SSF55326 13 133 9.07E-29 T 29-03-2018 IPR016188 PurM-like, N-terminal domain GBCGDNIH2_RS05425 e60881dd2aead5c90c044fa18358967a 312 Gene3D G3DSA:3.90.650.10 139 312 2.1E-34 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain GBCGDNIH2_RS10630 164e89741ae9aa2bfb8bc11c91b5ac80 140 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 3 138 34.547 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 GBCGDNIH2_RS10630 164e89741ae9aa2bfb8bc11c91b5ac80 140 SUPERFAMILY SSF54919 1 139 4.06E-56 T 29-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 GBCGDNIH2_RS10630 164e89741ae9aa2bfb8bc11c91b5ac80 140 Gene3D G3DSA:3.30.70.141 55 140 5.0E-34 T 29-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 GBCGDNIH2_RS10630 164e89741ae9aa2bfb8bc11c91b5ac80 140 Gene3D G3DSA:3.30.70.141 1 54 9.1E-16 T 29-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 GBCGDNIH2_RS10630 164e89741ae9aa2bfb8bc11c91b5ac80 140 Pfam PF00334 Nucleoside diphosphate kinase 4 138 2.5E-53 T 29-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 GBCGDNIH2_RS10630 164e89741ae9aa2bfb8bc11c91b5ac80 140 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 4.9E-36 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 GBCGDNIH2_RS10630 164e89741ae9aa2bfb8bc11c91b5ac80 140 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 4.9E-36 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 GBCGDNIH2_RS10630 164e89741ae9aa2bfb8bc11c91b5ac80 140 PRINTS PR01243 Nucleoside diphosphate kinase signature 50 69 4.9E-36 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 GBCGDNIH2_RS10630 164e89741ae9aa2bfb8bc11c91b5ac80 140 PRINTS PR01243 Nucleoside diphosphate kinase signature 6 28 4.9E-36 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 GBCGDNIH2_RS10630 164e89741ae9aa2bfb8bc11c91b5ac80 140 PRINTS PR01243 Nucleoside diphosphate kinase signature 70 87 4.9E-36 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 GBCGDNIH2_RS10630 164e89741ae9aa2bfb8bc11c91b5ac80 140 SMART SM00562 3 140 5.2E-84 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 GBCGDNIH2_RS00780 b099c6c424cccbddaef8200c2cf6b520 442 SMART SM00382 42 224 1.2E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS00780 b099c6c424cccbddaef8200c2cf6b520 442 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GBCGDNIH2_RS00780 b099c6c424cccbddaef8200c2cf6b520 442 SUPERFAMILY SSF52540 12 253 4.5E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS00780 b099c6c424cccbddaef8200c2cf6b520 442 Gene3D G3DSA:3.40.50.300 9 253 2.6E-62 T 29-03-2018 GBCGDNIH2_RS00780 b099c6c424cccbddaef8200c2cf6b520 442 Pfam PF09821 C-terminal AAA-associated domain 307 424 1.7E-42 T 29-03-2018 IPR018632 C-terminal AAA-associated domain GBCGDNIH2_RS00780 b099c6c424cccbddaef8200c2cf6b520 442 Pfam PF00005 ABC transporter 33 172 2.7E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GBCGDNIH2_RS00510 000cb293a039b73856ca752443be8f04 224 SUPERFAMILY SSF55120 9 218 2.24E-52 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 GBCGDNIH2_RS00510 000cb293a039b73856ca752443be8f04 224 Pfam PF00849 RNA pseudouridylate synthase 19 171 3.2E-28 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 GBCGDNIH2_RS00510 000cb293a039b73856ca752443be8f04 224 Gene3D G3DSA:3.30.2350.10 10 221 3.5E-56 T 29-03-2018 GBCGDNIH2_RS00510 000cb293a039b73856ca752443be8f04 224 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 58 72 - T 29-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 GBCGDNIH2_RS09155 d395e98dd864ea51818d9f169d1b241f 214 Pfam PF09347 Domain of unknown function (DUF1989) 17 185 2.1E-64 T 29-03-2018 IPR018959 Domain of unknown function DUF1989 GBCGDNIH2_RS09155 d395e98dd864ea51818d9f169d1b241f 214 TIGRFAM TIGR03424 urea_degr_1: urea carboxylase-associated protein 1 13 211 1.2E-101 T 29-03-2018 IPR017791 Urea carboxylase-associated protein 1 GBCGDNIH2_RS09070 487a2f6c50e9b686dfecf2d6c0cb5d18 430 Gene3D G3DSA:3.40.190.10 149 365 4.3E-33 T 29-03-2018 GBCGDNIH2_RS09070 487a2f6c50e9b686dfecf2d6c0cb5d18 430 Pfam PF13379 NMT1-like family 19 283 1.2E-67 T 29-03-2018 GBCGDNIH2_RS09070 487a2f6c50e9b686dfecf2d6c0cb5d18 430 SUPERFAMILY SSF53850 22 271 6.98E-19 T 29-03-2018 GBCGDNIH2_RS09070 487a2f6c50e9b686dfecf2d6c0cb5d18 430 Gene3D G3DSA:3.40.190.10 17 125 2.5E-4 T 29-03-2018 GBCGDNIH2_RS12005 5147562cc9d36ab4ad7e93d6708d71e0 292 Gene3D G3DSA:2.60.40.730 38 147 0.003 T 29-03-2018 GBCGDNIH2_RS12005 5147562cc9d36ab4ad7e93d6708d71e0 292 TIGRFAM TIGR04557 fuse_rel_SoxYZ: quinoprotein dehydrogenase-associated SoxYZ-like carrier 37 270 3.5E-72 T 29-03-2018 IPR030831 Quinoprotein dehydrogenase-associated SoxYZ-like carrier GBCGDNIH2_RS12005 5147562cc9d36ab4ad7e93d6708d71e0 292 SUPERFAMILY SSF81296 183 275 5.32E-22 T 29-03-2018 IPR014756 Immunoglobulin E-set GBCGDNIH2_RS12005 5147562cc9d36ab4ad7e93d6708d71e0 292 Gene3D G3DSA:2.60.40.10 180 275 1.0E-22 T 29-03-2018 IPR013783 Immunoglobulin-like fold GBCGDNIH2_RS12005 5147562cc9d36ab4ad7e93d6708d71e0 292 Pfam PF13501 Sulfur oxidation protein SoxY 43 150 3.1E-27 T 29-03-2018 IPR032711 Ig-like SoxY domain GBCGDNIH2_RS12005 5147562cc9d36ab4ad7e93d6708d71e0 292 Pfam PF08770 Sulphur oxidation protein SoxZ 187 273 3.0E-23 T 29-03-2018 IPR014880 Sulphur oxidation protein SoxZ GBCGDNIH2_RS10730 e14a9e6ac145307ad26858ce6c99fadd 742 Pfam PF00271 Helicase conserved C-terminal domain 543 604 9.0E-5 T 29-03-2018 IPR001650 Helicase, C-terminal GBCGDNIH2_RS10730 e14a9e6ac145307ad26858ce6c99fadd 742 Gene3D G3DSA:3.40.50.300 202 396 4.5E-28 T 29-03-2018 GBCGDNIH2_RS10730 e14a9e6ac145307ad26858ce6c99fadd 742 Hamap MF_00983 Probable primosomal protein N' [priA]. 12 741 23.554 T 29-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 GBCGDNIH2_RS10730 e14a9e6ac145307ad26858ce6c99fadd 742 SUPERFAMILY SSF52540 476 626 3.7E-18 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS10730 e14a9e6ac145307ad26858ce6c99fadd 742 SUPERFAMILY SSF52540 204 388 1.98E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS10730 e14a9e6ac145307ad26858ce6c99fadd 742 TIGRFAM TIGR00595 priA: primosomal protein N' 234 739 2.6E-186 T 29-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 GBCGDNIH2_RS10730 e14a9e6ac145307ad26858ce6c99fadd 742 Pfam PF00270 DEAD/DEAH box helicase 232 377 2.4E-13 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 GBCGDNIH2_RS10730 e14a9e6ac145307ad26858ce6c99fadd 742 Gene3D G3DSA:1.10.10.10 138 199 6.8E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS10730 e14a9e6ac145307ad26858ce6c99fadd 742 SMART SM00490 508 605 0.0076 T 29-03-2018 IPR001650 Helicase, C-terminal GBCGDNIH2_RS10730 e14a9e6ac145307ad26858ce6c99fadd 742 SMART SM00487 206 405 2.3E-21 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain GBCGDNIH2_RS10730 e14a9e6ac145307ad26858ce6c99fadd 742 Gene3D G3DSA:3.40.50.300 420 640 1.6E-17 T 29-03-2018 GBCGDNIH2_RS05180 e6ca511e32383472213e6a93dd354931 483 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 11 483 36.698 T 29-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 GBCGDNIH2_RS05180 e6ca511e32383472213e6a93dd354931 483 Pfam PF02934 GatB/GatE catalytic domain 14 297 1.1E-113 T 29-03-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 GBCGDNIH2_RS05180 e6ca511e32383472213e6a93dd354931 483 SUPERFAMILY SSF55931 13 304 1.18E-115 T 29-03-2018 GBCGDNIH2_RS05180 e6ca511e32383472213e6a93dd354931 483 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 12 482 9.5E-161 T 29-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 GBCGDNIH2_RS05180 e6ca511e32383472213e6a93dd354931 483 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 153 167 - T 29-03-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 GBCGDNIH2_RS05180 e6ca511e32383472213e6a93dd354931 483 SMART SM00845 336 482 2.4E-79 T 29-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 GBCGDNIH2_RS05180 e6ca511e32383472213e6a93dd354931 483 Pfam PF02637 GatB domain 337 482 5.6E-47 T 29-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 GBCGDNIH2_RS05180 e6ca511e32383472213e6a93dd354931 483 SUPERFAMILY SSF89095 305 410 3.05E-31 T 29-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 GBCGDNIH2_RS05180 e6ca511e32383472213e6a93dd354931 483 Gene3D G3DSA:1.10.10.410 422 483 3.6E-21 T 29-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal GBCGDNIH2_RS07075 c0ed831526932bb0d84f7d3172381dbe 763 Pfam PF00271 Helicase conserved C-terminal domain 450 559 4.1E-27 T 29-03-2018 IPR001650 Helicase, C-terminal GBCGDNIH2_RS07075 c0ed831526932bb0d84f7d3172381dbe 763 SUPERFAMILY SSF52540 295 578 2.16E-71 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS07075 c0ed831526932bb0d84f7d3172381dbe 763 Gene3D G3DSA:3.40.50.300 6 444 1.4E-60 T 29-03-2018 GBCGDNIH2_RS07075 c0ed831526932bb0d84f7d3172381dbe 763 SMART SM00487 242 442 3.5E-61 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain GBCGDNIH2_RS07075 c0ed831526932bb0d84f7d3172381dbe 763 SMART SM00490 478 559 3.6E-30 T 29-03-2018 IPR001650 Helicase, C-terminal GBCGDNIH2_RS07075 c0ed831526932bb0d84f7d3172381dbe 763 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 373 381 - T 29-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site GBCGDNIH2_RS07075 c0ed831526932bb0d84f7d3172381dbe 763 Pfam PF00270 DEAD/DEAH box helicase 247 414 5.3E-51 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 GBCGDNIH2_RS07075 c0ed831526932bb0d84f7d3172381dbe 763 Gene3D G3DSA:3.40.50.300 445 724 3.8E-43 T 29-03-2018 GBCGDNIH2_RS10475 0f1e53e167c7facd087cad13fef32cdc 248 SUPERFAMILY SSF53448 1 239 2.93E-43 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS10475 0f1e53e167c7facd087cad13fef32cdc 248 Gene3D G3DSA:3.90.550.10 1 245 1.7E-36 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS10475 0f1e53e167c7facd087cad13fef32cdc 248 Pfam PF12804 MobA-like NTP transferase domain 6 134 1.6E-16 T 29-03-2018 IPR025877 MobA-like NTP transferase GBCGDNIH2_RS06430 038910fa4efb1c583be142067bb3f45f 152 SUPERFAMILY SSF101307 36 144 7.72E-22 T 29-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 GBCGDNIH2_RS06430 038910fa4efb1c583be142067bb3f45f 152 Gene3D G3DSA:1.10.3760.10 40 149 3.3E-25 T 29-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 GBCGDNIH2_RS06430 038910fa4efb1c583be142067bb3f45f 152 PIRSF PIRSF006162 1 150 5.6E-28 T 29-03-2018 IPR026037 Phosphatidylglycerophosphatase A KEGG: 00564+3.1.3.27|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 GBCGDNIH2_RS06430 038910fa4efb1c583be142067bb3f45f 152 Pfam PF04608 Phosphatidylglycerophosphatase A 5 143 2.9E-33 T 29-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 GBCGDNIH2_RS09075 43e02d80c6be0dfca702f853ada5eda7 212 PIRSF PIRSF036382 1 195 2.0E-58 T 29-03-2018 IPR008327 Signal transduction response regulator, antiterminator GBCGDNIH2_RS09075 43e02d80c6be0dfca702f853ada5eda7 212 Pfam PF00072 Response regulator receiver domain 8 113 2.4E-7 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GBCGDNIH2_RS09075 43e02d80c6be0dfca702f853ada5eda7 212 SUPERFAMILY SSF52172 4 188 3.42E-46 T 29-03-2018 IPR011006 CheY-like superfamily GBCGDNIH2_RS09075 43e02d80c6be0dfca702f853ada5eda7 212 Gene3D G3DSA:3.40.50.2300 3 147 3.4E-16 T 29-03-2018 GBCGDNIH2_RS09075 43e02d80c6be0dfca702f853ada5eda7 212 Gene3D G3DSA:1.10.10.10 148 190 7.2E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS09075 43e02d80c6be0dfca702f853ada5eda7 212 Pfam PF03861 ANTAR domain 136 188 1.4E-18 T 29-03-2018 IPR005561 ANTAR domain GO:0003723 GBCGDNIH2_RS09075 43e02d80c6be0dfca702f853ada5eda7 212 SMART SM01012 133 188 1.8E-23 T 29-03-2018 IPR005561 ANTAR domain GO:0003723 GBCGDNIH2_RS11430 797e1f4494c7ea6bc6d9157f78e2791b 149 Gene3D G3DSA:3.40.50.10110 1 141 1.0E-36 T 29-03-2018 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 GBCGDNIH2_RS11430 797e1f4494c7ea6bc6d9157f78e2791b 149 Pfam PF04364 DNA polymerase III chi subunit, HolC 1 136 2.3E-33 T 29-03-2018 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 GBCGDNIH2_RS11430 797e1f4494c7ea6bc6d9157f78e2791b 149 SUPERFAMILY SSF102400 1 140 1.96E-37 T 29-03-2018 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 GBCGDNIH2_RS07840 9894a9d83f3a8040d5d8bdc960400ce9 527 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 15 511 2.0E-204 T 29-03-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 GBCGDNIH2_RS07840 9894a9d83f3a8040d5d8bdc960400ce9 527 Gene3D G3DSA:3.20.20.70 9 345 3.4E-107 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS07840 9894a9d83f3a8040d5d8bdc960400ce9 527 SMART SM00917 384 514 2.0E-38 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 GBCGDNIH2_RS07840 9894a9d83f3a8040d5d8bdc960400ce9 527 Hamap MF_01025 2-isopropylmalate synthase [leuA]. 13 523 41.079 T 29-03-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 GBCGDNIH2_RS07840 9894a9d83f3a8040d5d8bdc960400ce9 527 SUPERFAMILY SSF51569 13 305 1.28E-91 T 29-03-2018 GBCGDNIH2_RS07840 9894a9d83f3a8040d5d8bdc960400ce9 527 Pfam PF00682 HMGL-like 15 286 9.2E-89 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 GBCGDNIH2_RS07840 9894a9d83f3a8040d5d8bdc960400ce9 527 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 213 226 - T 29-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 GBCGDNIH2_RS07840 9894a9d83f3a8040d5d8bdc960400ce9 527 SUPERFAMILY SSF110921 406 513 1.83E-25 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 GBCGDNIH2_RS07840 9894a9d83f3a8040d5d8bdc960400ce9 527 Pfam PF08502 LeuA allosteric (dimerisation) domain 385 514 3.1E-36 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 GBCGDNIH2_RS07840 9894a9d83f3a8040d5d8bdc960400ce9 527 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 23 39 - T 29-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 GBCGDNIH2_RS01205 54f0ee72b3e4b19ea5455804e36b3398 291 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 87 109 - T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 GBCGDNIH2_RS01205 54f0ee72b3e4b19ea5455804e36b3398 291 Pfam PF01066 CDP-alcohol phosphatidyltransferase 42 109 1.3E-12 T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 GBCGDNIH2_RS06835 b98155aee4e091d2ca4fabc4319dc7b3 126 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 23 96 1.0E-15 T 29-03-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 GBCGDNIH2_RS06835 b98155aee4e091d2ca4fabc4319dc7b3 126 TIGRFAM TIGR02847 CyoD: cytochrome o ubiquinol oxidase subunit IV 16 110 3.8E-34 T 29-03-2018 IPR014210 Cytochrome o ubiquinol oxidase subunit IV GO:0008827|GO:0015990|GO:0016021 GBCGDNIH2_RS11525 e12e834b4ea04ed62a5bd57aa22442e1 222 Gene3D G3DSA:1.20.144.10 5 221 1.2E-16 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase GBCGDNIH2_RS11525 e12e834b4ea04ed62a5bd57aa22442e1 222 Pfam PF01569 PAP2 superfamily 93 212 8.6E-15 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase GBCGDNIH2_RS11525 e12e834b4ea04ed62a5bd57aa22442e1 222 SUPERFAMILY SSF48317 20 217 1.83E-22 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase GBCGDNIH2_RS11525 e12e834b4ea04ed62a5bd57aa22442e1 222 SMART SM00014 93 213 7.5E-5 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase GBCGDNIH2_RS00045 cd9b07c80a1eb999c2830b57388f8c78 304 Pfam PF13614 AAA domain 39 220 4.5E-58 T 29-03-2018 IPR025669 AAA domain GBCGDNIH2_RS00045 cd9b07c80a1eb999c2830b57388f8c78 304 SUPERFAMILY SSF52540 38 297 1.76E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS00045 cd9b07c80a1eb999c2830b57388f8c78 304 Gene3D G3DSA:3.40.50.300 37 303 1.8E-62 T 29-03-2018 GBCGDNIH2_RS01640 26f05d29ba7f5bae0d5f464ecaac39fe 482 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 168 473 1.6E-95 T 29-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 GBCGDNIH2_RS01640 26f05d29ba7f5bae0d5f464ecaac39fe 482 SUPERFAMILY SSF52949 59 156 1.88E-5 T 29-03-2018 GBCGDNIH2_RS01640 26f05d29ba7f5bae0d5f464ecaac39fe 482 SUPERFAMILY SSF53187 163 479 1.72E-97 T 29-03-2018 GBCGDNIH2_RS01640 26f05d29ba7f5bae0d5f464ecaac39fe 482 Gene3D G3DSA:3.40.220.10 26 157 4.3E-9 T 29-03-2018 GBCGDNIH2_RS01640 26f05d29ba7f5bae0d5f464ecaac39fe 482 PRINTS PR00481 Cytosol aminopeptidase signature 326 346 4.1E-42 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 GBCGDNIH2_RS01640 26f05d29ba7f5bae0d5f464ecaac39fe 482 PRINTS PR00481 Cytosol aminopeptidase signature 267 288 4.1E-42 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 GBCGDNIH2_RS01640 26f05d29ba7f5bae0d5f464ecaac39fe 482 PRINTS PR00481 Cytosol aminopeptidase signature 354 369 4.1E-42 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 GBCGDNIH2_RS01640 26f05d29ba7f5bae0d5f464ecaac39fe 482 PRINTS PR00481 Cytosol aminopeptidase signature 304 325 4.1E-42 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 GBCGDNIH2_RS01640 26f05d29ba7f5bae0d5f464ecaac39fe 482 PRINTS PR00481 Cytosol aminopeptidase signature 245 262 4.1E-42 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 GBCGDNIH2_RS01640 26f05d29ba7f5bae0d5f464ecaac39fe 482 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 330 337 - T 29-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 GBCGDNIH2_RS01640 26f05d29ba7f5bae0d5f464ecaac39fe 482 Gene3D G3DSA:3.40.630.10 158 481 1.6E-108 T 29-03-2018 GBCGDNIH2_RS12385 55c562635b45594fe74a1e5e7dcae86f 83 Pfam PF11324 Protein of unknown function (DUF3126) 5 67 4.3E-26 T 29-03-2018 IPR021473 Protein of unknown function DUF3126 GBCGDNIH2_RS06870 d6b3d80e3090b2baa90b1afbe465b2d0 186 Gene3D G3DSA:1.25.40.10 12 56 0.0052 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS06870 d6b3d80e3090b2baa90b1afbe465b2d0 186 Pfam PF07719 Tetratricopeptide repeat 96 126 3.3E-6 T 29-03-2018 IPR013105 Tetratricopeptide repeat 2 GBCGDNIH2_RS06870 d6b3d80e3090b2baa90b1afbe465b2d0 186 SMART SM00028 39 72 100.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 GBCGDNIH2_RS06870 d6b3d80e3090b2baa90b1afbe465b2d0 186 SMART SM00028 94 127 8.8E-4 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 GBCGDNIH2_RS06870 d6b3d80e3090b2baa90b1afbe465b2d0 186 SUPERFAMILY SSF48452 23 129 1.65E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS06870 d6b3d80e3090b2baa90b1afbe465b2d0 186 Gene3D G3DSA:1.25.40.10 57 150 2.5E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS11845 0bdcd2e0b5c380a1aae78954922d370d 448 SUPERFAMILY SSF52317 229 446 1.09E-61 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like GBCGDNIH2_RS11845 0bdcd2e0b5c380a1aae78954922d370d 448 SMART SM01097 74 206 4.0E-77 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 GBCGDNIH2_RS11845 0bdcd2e0b5c380a1aae78954922d370d 448 Gene3D G3DSA:3.50.30.20 73 226 3.1E-52 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 GBCGDNIH2_RS11845 0bdcd2e0b5c380a1aae78954922d370d 448 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 265 279 2.4E-39 T 29-03-2018 GBCGDNIH2_RS11845 0bdcd2e0b5c380a1aae78954922d370d 448 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 353 370 2.4E-39 T 29-03-2018 GBCGDNIH2_RS11845 0bdcd2e0b5c380a1aae78954922d370d 448 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 336 352 2.4E-39 T 29-03-2018 GBCGDNIH2_RS11845 0bdcd2e0b5c380a1aae78954922d370d 448 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 304 318 2.4E-39 T 29-03-2018 GBCGDNIH2_RS11845 0bdcd2e0b5c380a1aae78954922d370d 448 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 378 389 2.4E-39 T 29-03-2018 GBCGDNIH2_RS11845 0bdcd2e0b5c380a1aae78954922d370d 448 Pfam PF00117 Glutamine amidotransferase class-I 268 444 1.4E-45 T 29-03-2018 IPR017926 Glutamine amidotransferase GBCGDNIH2_RS11845 0bdcd2e0b5c380a1aae78954922d370d 448 PRINTS PR00096 Glutamine amidotransferase superfamily signature 336 347 2.6E-12 T 29-03-2018 GBCGDNIH2_RS11845 0bdcd2e0b5c380a1aae78954922d370d 448 PRINTS PR00096 Glutamine amidotransferase superfamily signature 421 434 2.6E-12 T 29-03-2018 GBCGDNIH2_RS11845 0bdcd2e0b5c380a1aae78954922d370d 448 PRINTS PR00096 Glutamine amidotransferase superfamily signature 307 316 2.6E-12 T 29-03-2018 GBCGDNIH2_RS11845 0bdcd2e0b5c380a1aae78954922d370d 448 PRINTS PR00097 Anthranilate synthase component II signature 336 347 1.3E-6 T 29-03-2018 GBCGDNIH2_RS11845 0bdcd2e0b5c380a1aae78954922d370d 448 PRINTS PR00097 Anthranilate synthase component II signature 307 316 1.3E-6 T 29-03-2018 GBCGDNIH2_RS11845 0bdcd2e0b5c380a1aae78954922d370d 448 PRINTS PR00097 Anthranilate synthase component II signature 421 434 1.3E-6 T 29-03-2018 GBCGDNIH2_RS11845 0bdcd2e0b5c380a1aae78954922d370d 448 Gene3D G3DSA:3.40.50.880 227 448 6.1E-65 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like GBCGDNIH2_RS11845 0bdcd2e0b5c380a1aae78954922d370d 448 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 74 448 45.67 T 29-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 GBCGDNIH2_RS11845 0bdcd2e0b5c380a1aae78954922d370d 448 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 76 205 3.0E-47 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 GBCGDNIH2_RS11845 0bdcd2e0b5c380a1aae78954922d370d 448 Gene3D G3DSA:1.10.260.40 1 55 1.8E-5 T 29-03-2018 GBCGDNIH2_RS11845 0bdcd2e0b5c380a1aae78954922d370d 448 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 76 446 1.6E-135 T 29-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 GBCGDNIH2_RS11845 0bdcd2e0b5c380a1aae78954922d370d 448 SUPERFAMILY SSF52021 75 220 1.7E-49 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 GBCGDNIH2_RS04620 53262c8302ea80a1ff86a6c78cc8c905 244 Gene3D G3DSA:3.60.21.10 34 213 4.5E-9 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like GBCGDNIH2_RS04620 53262c8302ea80a1ff86a6c78cc8c905 244 SUPERFAMILY SSF56300 195 220 9.59E-12 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like GBCGDNIH2_RS04620 53262c8302ea80a1ff86a6c78cc8c905 244 SUPERFAMILY SSF56300 34 163 9.59E-12 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like GBCGDNIH2_RS04620 53262c8302ea80a1ff86a6c78cc8c905 244 TIGRFAM TIGR04123 P_estr_lig_assc: metallophosphoesterase, DNA ligase-associated 14 221 3.2E-65 T 29-03-2018 IPR026336 Metallophosphoesterase, DNA ligase-associated GBCGDNIH2_RS04620 53262c8302ea80a1ff86a6c78cc8c905 244 Pfam PF00149 Calcineurin-like phosphoesterase 34 131 3.6E-6 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 GBCGDNIH2_RS04620 53262c8302ea80a1ff86a6c78cc8c905 244 PIRSF PIRSF000887 13 220 8.8E-38 T 29-03-2018 IPR024173 Phosphoesterase, MJ0037 GBCGDNIH2_RS01355 6e3594f57ec109cf1d06d18b998d86cc 238 TIGRFAM TIGR03142 cytochro_ccmI: cytochrome c-type biogenesis protein CcmI 1 111 2.4E-17 T 29-03-2018 IPR017560 Cytochrome c-type biogenesis protein CcmI GBCGDNIH2_RS01355 6e3594f57ec109cf1d06d18b998d86cc 238 Gene3D G3DSA:1.25.20.10 18 230 1.9E-6 T 29-03-2018 GBCGDNIH2_RS09355 455556391519957b353ebc3451809d43 160 SUPERFAMILY SSF46785 41 156 2.42E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS09355 455556391519957b353ebc3451809d43 160 Pfam PF01047 MarR family 56 108 1.2E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GBCGDNIH2_RS09355 455556391519957b353ebc3451809d43 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 85 100 1.9E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GBCGDNIH2_RS09355 455556391519957b353ebc3451809d43 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 104 120 1.9E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GBCGDNIH2_RS09355 455556391519957b353ebc3451809d43 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 134 154 1.9E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GBCGDNIH2_RS09355 455556391519957b353ebc3451809d43 160 Gene3D G3DSA:1.10.10.10 3 160 2.0E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS09355 455556391519957b353ebc3451809d43 160 ProSitePatterns PS01117 MarR-type HTH domain signature. 83 117 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site GBCGDNIH2_RS09355 455556391519957b353ebc3451809d43 160 SMART SM00347 44 144 5.3E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GBCGDNIH2_RS05115 9148b1d062548b5b9a56d401de9dd6c7 376 SMART SM00228 125 202 0.001 T 29-03-2018 IPR001478 PDZ domain GO:0005515 GBCGDNIH2_RS05115 9148b1d062548b5b9a56d401de9dd6c7 376 Gene3D G3DSA:2.30.42.10 145 231 1.2E-17 T 29-03-2018 GBCGDNIH2_RS05115 9148b1d062548b5b9a56d401de9dd6c7 376 Pfam PF13180 PDZ domain 147 210 1.5E-8 T 29-03-2018 IPR001478 PDZ domain GO:0005515 GBCGDNIH2_RS05115 9148b1d062548b5b9a56d401de9dd6c7 376 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 146 365 1.5E-53 T 29-03-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 GBCGDNIH2_RS05115 9148b1d062548b5b9a56d401de9dd6c7 376 Pfam PF02163 Peptidase family M50 12 352 6.2E-73 T 29-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 GBCGDNIH2_RS05115 9148b1d062548b5b9a56d401de9dd6c7 376 SUPERFAMILY SSF50156 105 211 1.16E-17 T 29-03-2018 IPR001478 PDZ domain GO:0005515 GBCGDNIH2_RS08335 d546783039676013bd8c2275ee7793d8 358 Pfam PF11863 Protein of unknown function (DUF3383) 87 353 1.9E-51 T 29-03-2018 IPR021808 Protein of unknown function DUF3383 GBCGDNIH2_RS04345 6b77d6821fbc7295a63c470182783d39 429 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 429 205.474 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 GBCGDNIH2_RS04345 6b77d6821fbc7295a63c470182783d39 429 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 132 143 - T 29-03-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 GBCGDNIH2_RS04345 6b77d6821fbc7295a63c470182783d39 429 Gene3D G3DSA:3.90.170.10 265 429 3.4E-67 T 29-03-2018 GBCGDNIH2_RS04345 6b77d6821fbc7295a63c470182783d39 429 SUPERFAMILY SSF52540 1 423 3.08E-164 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS04345 6b77d6821fbc7295a63c470182783d39 429 SMART SM00788 3 422 3.0E-278 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 GBCGDNIH2_RS04345 6b77d6821fbc7295a63c470182783d39 429 Gene3D G3DSA:3.40.440.10 1 153 5.3E-50 T 29-03-2018 GBCGDNIH2_RS04345 6b77d6821fbc7295a63c470182783d39 429 Gene3D G3DSA:3.40.440.10 154 264 6.0E-22 T 29-03-2018 GBCGDNIH2_RS04345 6b77d6821fbc7295a63c470182783d39 429 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 6 427 4.7E-153 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 GBCGDNIH2_RS04345 6b77d6821fbc7295a63c470182783d39 429 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 29-03-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 GBCGDNIH2_RS04345 6b77d6821fbc7295a63c470182783d39 429 Pfam PF00709 Adenylosuccinate synthetase 4 421 6.4E-169 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 GBCGDNIH2_RS01755 f2ea819084ce52dc3ef70bbc855b905b 232 Gene3D G3DSA:1.20.950.20 8 212 1.7E-20 T 29-03-2018 GBCGDNIH2_RS01755 f2ea819084ce52dc3ef70bbc855b905b 232 SUPERFAMILY SSF81342 11 201 1.26E-19 T 29-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 GBCGDNIH2_RS01755 f2ea819084ce52dc3ef70bbc855b905b 232 Pfam PF01292 Prokaryotic cytochrome b561 13 193 5.9E-16 T 29-03-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 GBCGDNIH2_RS04200 baa0e2dd4384718a5434e7e015827a9f 162 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 9 156 1.1E-63 T 29-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 GBCGDNIH2_RS04200 baa0e2dd4384718a5434e7e015827a9f 162 SUPERFAMILY SSF55040 16 159 2.09E-58 T 29-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 GBCGDNIH2_RS04200 baa0e2dd4384718a5434e7e015827a9f 162 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase accessory protein [moaC]. 7 162 36.325 T 29-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 GBCGDNIH2_RS04200 baa0e2dd4384718a5434e7e015827a9f 162 Gene3D G3DSA:3.30.70.640 7 162 1.1E-67 T 29-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 GBCGDNIH2_RS04200 baa0e2dd4384718a5434e7e015827a9f 162 Pfam PF01967 MoaC family 20 154 5.4E-56 T 29-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 GBCGDNIH2_RS07190 c9dd5545b09f99de3cb9750af1d2a039 311 SUPERFAMILY SSF53590 8 308 1.03E-79 T 29-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain GBCGDNIH2_RS07190 c9dd5545b09f99de3cb9750af1d2a039 311 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 10 300 7.5E-74 T 29-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain GBCGDNIH2_RS07190 c9dd5545b09f99de3cb9750af1d2a039 311 Gene3D G3DSA:3.90.245.10 2 310 3.6E-89 T 29-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain GBCGDNIH2_RS07125 78707c6907fdf34d15f4bf568e64ee9d 172 SMART SM00972 111 169 7.4E-23 T 29-03-2018 IPR007893 Spore coat protein U GBCGDNIH2_RS07125 78707c6907fdf34d15f4bf568e64ee9d 172 Pfam PF05229 Spore Coat Protein U domain 38 169 2.1E-35 T 29-03-2018 IPR007893 Spore coat protein U GBCGDNIH2_RS03400 66910eae0582926ca6d61fc23bb9a885 441 Gene3D G3DSA:3.40.50.880 245 439 1.8E-13 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like GBCGDNIH2_RS03400 66910eae0582926ca6d61fc23bb9a885 441 SUPERFAMILY SSF52317 247 436 1.49E-24 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like GBCGDNIH2_RS03400 66910eae0582926ca6d61fc23bb9a885 441 Hamap MF_00027 Cobyrinate a,c-diamide synthase [cbiA]. 4 441 38.962 T 29-03-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 GBCGDNIH2_RS03400 66910eae0582926ca6d61fc23bb9a885 441 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 8 436 4.2E-85 T 29-03-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 GBCGDNIH2_RS03400 66910eae0582926ca6d61fc23bb9a885 441 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 249 439 7.4E-30 T 29-03-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 GBCGDNIH2_RS03400 66910eae0582926ca6d61fc23bb9a885 441 SUPERFAMILY SSF52540 5 200 1.73E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS03400 66910eae0582926ca6d61fc23bb9a885 441 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 7 193 4.4E-15 T 29-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain GBCGDNIH2_RS03400 66910eae0582926ca6d61fc23bb9a885 441 Gene3D G3DSA:3.40.50.300 1 190 1.3E-33 T 29-03-2018 GBCGDNIH2_RS08815 5827b0bf4f32f6939c13c1f2f4b0e197 408 PRINTS PR00410 Phenol hydroxylase reductase family signature 267 286 2.1E-7 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 GBCGDNIH2_RS08815 5827b0bf4f32f6939c13c1f2f4b0e197 408 PRINTS PR00410 Phenol hydroxylase reductase family signature 367 375 2.1E-7 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 GBCGDNIH2_RS08815 5827b0bf4f32f6939c13c1f2f4b0e197 408 PRINTS PR00410 Phenol hydroxylase reductase family signature 251 260 2.1E-7 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 GBCGDNIH2_RS08815 5827b0bf4f32f6939c13c1f2f4b0e197 408 PRINTS PR00410 Phenol hydroxylase reductase family signature 187 199 2.1E-7 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 GBCGDNIH2_RS08815 5827b0bf4f32f6939c13c1f2f4b0e197 408 SUPERFAMILY SSF52343 258 401 3.67E-34 T 29-03-2018 GBCGDNIH2_RS08815 5827b0bf4f32f6939c13c1f2f4b0e197 408 Gene3D G3DSA:3.40.50.80 258 405 4.8E-26 T 29-03-2018 GBCGDNIH2_RS08815 5827b0bf4f32f6939c13c1f2f4b0e197 408 Gene3D G3DSA:1.10.490.10 1 161 2.6E-36 T 29-03-2018 GBCGDNIH2_RS08815 5827b0bf4f32f6939c13c1f2f4b0e197 408 SUPERFAMILY SSF46458 4 137 1.2E-32 T 29-03-2018 IPR009050 Globin-like GBCGDNIH2_RS08815 5827b0bf4f32f6939c13c1f2f4b0e197 408 Pfam PF00175 Oxidoreductase NAD-binding domain 268 379 3.8E-15 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 GBCGDNIH2_RS08815 5827b0bf4f32f6939c13c1f2f4b0e197 408 SUPERFAMILY SSF63380 152 256 7.15E-26 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 GBCGDNIH2_RS08815 5827b0bf4f32f6939c13c1f2f4b0e197 408 Pfam PF00970 Oxidoreductase FAD-binding domain 162 256 3.1E-5 T 29-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 GBCGDNIH2_RS08815 5827b0bf4f32f6939c13c1f2f4b0e197 408 Gene3D G3DSA:2.40.30.10 162 257 7.7E-23 T 29-03-2018 GBCGDNIH2_RS07680 338254065c6693b55a907517ed7ec0f0 393 TIGRFAM TIGR00215 lpxB: lipid-A-disaccharide synthase 5 369 3.8E-82 T 29-03-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 GBCGDNIH2_RS07680 338254065c6693b55a907517ed7ec0f0 393 Pfam PF02684 Lipid-A-disaccharide synthetase 6 344 6.3E-96 T 29-03-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 GBCGDNIH2_RS07680 338254065c6693b55a907517ed7ec0f0 393 Gene3D G3DSA:3.40.50.2000 172 363 5.3E-14 T 29-03-2018 GBCGDNIH2_RS07680 338254065c6693b55a907517ed7ec0f0 393 SUPERFAMILY SSF53756 6 310 2.95E-29 T 29-03-2018 GBCGDNIH2_RS07680 338254065c6693b55a907517ed7ec0f0 393 Hamap MF_00392 Lipid-A-disaccharide synthase [lpxB]. 3 388 33.584 T 29-03-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 GBCGDNIH2_RS11520 e2eaf0c028b68ef0d9db9fcbca022383 333 SUPERFAMILY SSF53474 80 302 6.17E-55 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS11520 e2eaf0c028b68ef0d9db9fcbca022383 333 ProSitePatterns PS01173 Lipolytic enzymes "G-D-X-G" family, putative histidine active site. 81 97 - T 29-03-2018 IPR002168 Lipase, GDXG, putative histidine active site GO:0008152|GO:0016787 Reactome: R-HSA-163560 GBCGDNIH2_RS11520 e2eaf0c028b68ef0d9db9fcbca022383 333 Pfam PF07859 alpha/beta hydrolase fold 81 280 5.4E-53 T 29-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 GBCGDNIH2_RS11520 e2eaf0c028b68ef0d9db9fcbca022383 333 Gene3D G3DSA:3.40.50.1820 23 315 6.5E-50 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS11520 e2eaf0c028b68ef0d9db9fcbca022383 333 ProSitePatterns PS01174 Lipolytic enzymes "G-D-X-G" family, putative serine active site. 148 160 - T 29-03-2018 IPR033140 Lipase, GDXG, putative serine active site GBCGDNIH2_RS10945 365fd4bb3f3d77d445920f1b82a97487 140 Gene3D G3DSA:3.10.450.50 2 140 3.1E-23 T 29-03-2018 GBCGDNIH2_RS10945 365fd4bb3f3d77d445920f1b82a97487 140 TIGRFAM TIGR02096 TIGR02096: conserved hypothetical protein 8 137 1.9E-30 T 29-03-2018 IPR011721 Conserved hypothetical protein CHP02096 GBCGDNIH2_RS10945 365fd4bb3f3d77d445920f1b82a97487 140 SUPERFAMILY SSF54427 1 137 3.47E-25 T 29-03-2018 IPR032710 NTF2-like domain GBCGDNIH2_RS10945 365fd4bb3f3d77d445920f1b82a97487 140 Pfam PF12680 SnoaL-like domain 9 123 5.6E-19 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain GBCGDNIH2_RS02645 f1f088f63ae38b080fb7c7d9f636dfa3 810 Gene3D G3DSA:3.40.50.150 268 549 4.4E-7 T 29-03-2018 GBCGDNIH2_RS02645 f1f088f63ae38b080fb7c7d9f636dfa3 810 SUPERFAMILY SSF53335 311 471 2.5E-11 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GBCGDNIH2_RS06910 f6761b3648c01e0c6735fa0705c64556 478 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 209 230 1.4E-6 T 29-03-2018 GBCGDNIH2_RS06910 f6761b3648c01e0c6735fa0705c64556 478 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 301 313 1.4E-6 T 29-03-2018 GBCGDNIH2_RS06910 f6761b3648c01e0c6735fa0705c64556 478 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 66 91 1.4E-6 T 29-03-2018 GBCGDNIH2_RS06910 f6761b3648c01e0c6735fa0705c64556 478 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 409 428 1.4E-6 T 29-03-2018 GBCGDNIH2_RS06910 f6761b3648c01e0c6735fa0705c64556 478 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 5 466 1.8E-145 T 29-03-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 GBCGDNIH2_RS06910 f6761b3648c01e0c6735fa0705c64556 478 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 1 466 18.588 T 29-03-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 GBCGDNIH2_RS06910 f6761b3648c01e0c6735fa0705c64556 478 Pfam PF00361 Proton-conducting membrane transporter 118 411 1.8E-83 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS02050 45d34cb60a0c157b64e513df554cdf8c 134 SUPERFAMILY SSF53062 1 130 5.49E-37 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 GBCGDNIH2_RS02050 45d34cb60a0c157b64e513df554cdf8c 134 Pfam PF03610 PTS system fructose IIA component 3 114 1.3E-27 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 GBCGDNIH2_RS02050 45d34cb60a0c157b64e513df554cdf8c 134 Gene3D G3DSA:3.40.50.510 1 131 1.2E-37 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 GBCGDNIH2_RS07975 b4f04b1f982e4b87a4d9542d956c8ae7 67 SUPERFAMILY SSF143034 2 64 2.09E-17 T 29-03-2018 GBCGDNIH2_RS07975 b4f04b1f982e4b87a4d9542d956c8ae7 67 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 29-03-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS07975 b4f04b1f982e4b87a4d9542d956c8ae7 67 PRINTS PR00064 Ribosomal protein L35 signature 36 54 1.1E-9 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 GBCGDNIH2_RS07975 b4f04b1f982e4b87a4d9542d956c8ae7 67 PRINTS PR00064 Ribosomal protein L35 signature 3 20 1.1E-9 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 GBCGDNIH2_RS07975 b4f04b1f982e4b87a4d9542d956c8ae7 67 PRINTS PR00064 Ribosomal protein L35 signature 21 35 1.1E-9 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 GBCGDNIH2_RS07975 b4f04b1f982e4b87a4d9542d956c8ae7 67 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 61 1.7E-17 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 GBCGDNIH2_RS07975 b4f04b1f982e4b87a4d9542d956c8ae7 67 Pfam PF01632 Ribosomal protein L35 2 60 4.4E-17 T 29-03-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS07975 b4f04b1f982e4b87a4d9542d956c8ae7 67 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 14.617 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 GBCGDNIH2_RS06070 fec5867c54029fe1aa2e9b7d7d7d01c8 219 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 87 178 1.6E-6 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 GBCGDNIH2_RS06070 fec5867c54029fe1aa2e9b7d7d7d01c8 219 SUPERFAMILY SSF56784 5 212 1.08E-39 T 29-03-2018 IPR023214 HAD-like domain GBCGDNIH2_RS06070 fec5867c54029fe1aa2e9b7d7d7d01c8 219 Pfam PF13419 Haloacid dehalogenase-like hydrolase 9 183 6.6E-29 T 29-03-2018 IPR023214 HAD-like domain GBCGDNIH2_RS06070 fec5867c54029fe1aa2e9b7d7d7d01c8 219 Gene3D G3DSA:3.40.50.1000 1 216 7.7E-29 T 29-03-2018 IPR023214 HAD-like domain GBCGDNIH2_RS02765 c62e9aa8c38ea45a3671b8bd1aa80c16 238 Gene3D G3DSA:3.40.50.300 2 207 1.2E-55 T 29-03-2018 GBCGDNIH2_RS02765 c62e9aa8c38ea45a3671b8bd1aa80c16 238 Pfam PF00005 ABC transporter 22 149 3.0E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GBCGDNIH2_RS02765 c62e9aa8c38ea45a3671b8bd1aa80c16 238 SMART SM00382 31 198 2.6E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS02765 c62e9aa8c38ea45a3671b8bd1aa80c16 238 SUPERFAMILY SSF52540 7 207 9.21E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS02765 c62e9aa8c38ea45a3671b8bd1aa80c16 238 ProSitePatterns PS00211 ABC transporters family signature. 121 135 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GBCGDNIH2_RS12450 1f1e60a1b2909c0d0408d1b979c85adb 478 TIGRFAM TIGR03471 HpnJ: hopanoid biosynthesis associated radical SAM protein HpnJ 2 472 1.7E-249 T 29-03-2018 IPR017834 Hopanoid biosynthesis associated radical SAM protein HpnJ GBCGDNIH2_RS12450 1f1e60a1b2909c0d0408d1b979c85adb 478 Gene3D G3DSA:3.20.20.70 152 475 1.0E-40 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS12450 1f1e60a1b2909c0d0408d1b979c85adb 478 SUPERFAMILY SSF102114 166 394 1.57E-46 T 29-03-2018 GBCGDNIH2_RS12450 1f1e60a1b2909c0d0408d1b979c85adb 478 SMART SM00729 197 403 2.9E-34 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 GBCGDNIH2_RS12450 1f1e60a1b2909c0d0408d1b979c85adb 478 Pfam PF04055 Radical SAM superfamily 203 362 7.9E-21 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 GBCGDNIH2_RS01055 46f933f220bb5c10c0aced06f0ecca84 308 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 76 295 3.1E-49 T 29-03-2018 GBCGDNIH2_RS01055 46f933f220bb5c10c0aced06f0ecca84 308 SUPERFAMILY SSF53335 39 293 2.52E-32 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GBCGDNIH2_RS01055 46f933f220bb5c10c0aced06f0ecca84 308 Gene3D G3DSA:3.40.50.150 90 295 4.6E-25 T 29-03-2018 GBCGDNIH2_RS00140 4469c1b2a2717a9e244cfd308fff592b 394 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 17 361 5.6E-95 T 29-03-2018 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 GBCGDNIH2_RS00140 4469c1b2a2717a9e244cfd308fff592b 394 SUPERFAMILY SSF102114 9 392 5.1E-105 T 29-03-2018 GBCGDNIH2_RS00140 4469c1b2a2717a9e244cfd308fff592b 394 Pfam PF06969 HemN C-terminal domain 318 382 5.0E-12 T 29-03-2018 IPR010723 HemN, C-terminal GBCGDNIH2_RS00140 4469c1b2a2717a9e244cfd308fff592b 394 SMART SM00729 15 234 5.7E-51 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 GBCGDNIH2_RS00140 4469c1b2a2717a9e244cfd308fff592b 394 Gene3D G3DSA:3.20.20.70 9 318 1.2E-42 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS00140 4469c1b2a2717a9e244cfd308fff592b 394 Pfam PF04055 Radical SAM superfamily 20 186 3.4E-17 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 GBCGDNIH2_RS10710 e28208a717884f0dd89d0c9880b16c97 135 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 2 132 19.759 T 29-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 GBCGDNIH2_RS10710 e28208a717884f0dd89d0c9880b16c97 135 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 9 89 1.0E-18 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 GBCGDNIH2_RS10710 e28208a717884f0dd89d0c9880b16c97 135 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 5 83 8.2E-27 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 GBCGDNIH2_RS10710 e28208a717884f0dd89d0c9880b16c97 135 SUPERFAMILY SSF51344 5 83 2.22E-22 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 GBCGDNIH2_RS10710 e28208a717884f0dd89d0c9880b16c97 135 Gene3D G3DSA:2.60.15.10 1 89 1.5E-26 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 GBCGDNIH2_RS10710 e28208a717884f0dd89d0c9880b16c97 135 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 4 133 3.0E-30 T 29-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 GBCGDNIH2_RS11740 8ff8fbf6b9b456ddc26a4472e797980c 179 Gene3D G3DSA:2.60.120.10 2 157 6.2E-40 T 29-03-2018 IPR014710 RmlC-like jelly roll fold GBCGDNIH2_RS11740 8ff8fbf6b9b456ddc26a4472e797980c 179 Hamap MF_01682 Acireductone dioxygenase [mtnD]. 1 172 36.309 T 29-03-2018 IPR023956 Acireductone dioxygenase ARD, bacteria GO:0005506|GO:0010308|GO:0010309|GO:0016151|GO:0019284|GO:0055114 KEGG: 00270+1.13.11.53+1.13.11.54|MetaCyc: PWY-4361|MetaCyc: PWY-5389 GBCGDNIH2_RS11740 8ff8fbf6b9b456ddc26a4472e797980c 179 SUPERFAMILY SSF51182 1 177 2.97E-39 T 29-03-2018 IPR011051 RmlC-like cupin domain GBCGDNIH2_RS11740 8ff8fbf6b9b456ddc26a4472e797980c 179 Pfam PF03079 ARD/ARD' family 3 165 5.6E-39 T 29-03-2018 IPR004313 Acireductone dioxygenase ARD family GO:0010309|GO:0055114 KEGG: 00270+1.13.11.54|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 GBCGDNIH2_RS05335 28b2a6fb42a111ce20e0fa7ff3b396b1 714 SUPERFAMILY SSF53448 130 416 3.6E-24 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS05335 28b2a6fb42a111ce20e0fa7ff3b396b1 714 Hamap MF_01072 Glucans biosynthesis glucosyltransferase H [mdoH]. 2 634 45.256 T 29-03-2018 IPR023725 Glucan biosynthesis glucosyltransferase H GO:0016758 GBCGDNIH2_RS05335 28b2a6fb42a111ce20e0fa7ff3b396b1 714 Pfam PF13632 Glycosyl transferase family group 2 229 440 2.2E-14 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 GBCGDNIH2_RS05335 28b2a6fb42a111ce20e0fa7ff3b396b1 714 Gene3D G3DSA:3.90.550.10 119 398 3.1E-20 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS03405 c1b798db339e38ba1f630304657f9ac4 448 Gene3D G3DSA:3.20.20.140 82 362 2.9E-60 T 29-03-2018 GBCGDNIH2_RS03405 c1b798db339e38ba1f630304657f9ac4 448 Pfam PF01979 Amidohydrolase family 70 434 4.3E-57 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 GBCGDNIH2_RS03405 c1b798db339e38ba1f630304657f9ac4 448 Gene3D G3DSA:2.30.40.10 11 81 1.3E-9 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 GBCGDNIH2_RS03405 c1b798db339e38ba1f630304657f9ac4 448 Gene3D G3DSA:2.30.40.10 363 437 0.018 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 GBCGDNIH2_RS03405 c1b798db339e38ba1f630304657f9ac4 448 SUPERFAMILY SSF51338 32 88 1.87E-9 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 GBCGDNIH2_RS03405 c1b798db339e38ba1f630304657f9ac4 448 TIGRFAM TIGR02967 guan_deamin: guanine deaminase 30 434 2.9E-159 T 29-03-2018 IPR014311 Guanine deaminase GO:0006147|GO:0008270|GO:0008892 KEGG: 00230+3.5.4.3|MetaCyc: PWY-5497|MetaCyc: PWY-6606|MetaCyc: PWY-6608|MetaCyc: PWY-7442|Reactome: R-HSA-74259 GBCGDNIH2_RS03405 c1b798db339e38ba1f630304657f9ac4 448 SUPERFAMILY SSF51556 72 376 2.84E-86 T 29-03-2018 IPR032466 Metal-dependent hydrolase GBCGDNIH2_RS00350 a89f414c15b21e9f8b2892240529635a 205 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 166 4.8E-29 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 GBCGDNIH2_RS00350 a89f414c15b21e9f8b2892240529635a 205 SUPERFAMILY SSF53254 1 166 2.36E-34 T 29-03-2018 IPR029033 Histidine phosphatase superfamily GBCGDNIH2_RS00350 a89f414c15b21e9f8b2892240529635a 205 PIRSF PIRSF000709 80 168 0.0055 T 29-03-2018 GBCGDNIH2_RS00350 a89f414c15b21e9f8b2892240529635a 205 SMART SM00855 2 155 4.1E-12 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 GBCGDNIH2_RS00350 a89f414c15b21e9f8b2892240529635a 205 Gene3D G3DSA:3.40.50.1240 1 177 1.1E-30 T 29-03-2018 IPR029033 Histidine phosphatase superfamily GBCGDNIH2_RS05565 15c6c86c28143a949ba7501a95f79bfc 59 Gene3D G3DSA:3.30.50.10 2 59 2.6E-18 T 29-03-2018 IPR013088 Zinc finger, NHR/GATA-type GO:0006355|GO:0008270 GBCGDNIH2_RS05565 15c6c86c28143a949ba7501a95f79bfc 59 SUPERFAMILY SSF57716 4 58 3.94E-15 T 29-03-2018 GBCGDNIH2_RS05565 15c6c86c28143a949ba7501a95f79bfc 59 Hamap MF_00649 DNA gyrase inhibitor YacG [yacG]. 1 58 13.465 T 29-03-2018 IPR005584 DNA gyrase inhibitor YacG GO:0008270 GBCGDNIH2_RS05565 15c6c86c28143a949ba7501a95f79bfc 59 Pfam PF03884 DNA gyrase inhibitor YacG 5 55 8.6E-20 T 29-03-2018 IPR005584 DNA gyrase inhibitor YacG GO:0008270 GBCGDNIH2_RS09975 8e2f1d5be94c6636c2eaf6bfcbf7f2c4 125 PRINTS PR00604 Class IA and IB cytochrome C signature 98 108 1.9E-22 T 29-03-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS09975 8e2f1d5be94c6636c2eaf6bfcbf7f2c4 125 PRINTS PR00604 Class IA and IB cytochrome C signature 115 123 1.9E-22 T 29-03-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS09975 8e2f1d5be94c6636c2eaf6bfcbf7f2c4 125 PRINTS PR00604 Class IA and IB cytochrome C signature 49 64 1.9E-22 T 29-03-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS09975 8e2f1d5be94c6636c2eaf6bfcbf7f2c4 125 PRINTS PR00604 Class IA and IB cytochrome C signature 37 44 1.9E-22 T 29-03-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS09975 8e2f1d5be94c6636c2eaf6bfcbf7f2c4 125 PRINTS PR00604 Class IA and IB cytochrome C signature 65 75 1.9E-22 T 29-03-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS09975 8e2f1d5be94c6636c2eaf6bfcbf7f2c4 125 PRINTS PR00604 Class IA and IB cytochrome C signature 79 95 1.9E-22 T 29-03-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS09975 8e2f1d5be94c6636c2eaf6bfcbf7f2c4 125 Pfam PF00034 Cytochrome c 28 125 5.2E-10 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 GBCGDNIH2_RS09975 8e2f1d5be94c6636c2eaf6bfcbf7f2c4 125 SUPERFAMILY SSF46626 25 125 1.92E-34 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 GBCGDNIH2_RS09975 8e2f1d5be94c6636c2eaf6bfcbf7f2c4 125 Gene3D G3DSA:1.10.760.10 7 125 3.4E-26 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 GBCGDNIH2_RS06465 c657da6a5920e445bfe658e0ed5f4096 383 Pfam PF06965 Na+/H+ antiporter 1 15 375 8.3E-129 T 29-03-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 GBCGDNIH2_RS06465 c657da6a5920e445bfe658e0ed5f4096 383 Gene3D G3DSA:1.20.1530.10 11 379 8.3E-130 T 29-03-2018 IPR023171 Na/H antiporter domain GBCGDNIH2_RS06465 c657da6a5920e445bfe658e0ed5f4096 383 TIGRFAM TIGR00773 NhaA: Na+/H+ antiporter NhaA 16 375 2.3E-112 T 29-03-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 GBCGDNIH2_RS06465 c657da6a5920e445bfe658e0ed5f4096 383 Hamap MF_01844 Na(+)/H(+) antiporter NhaA [nhaA]. 12 383 21.27 T 29-03-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 GBCGDNIH2_RS03705 91e18659f6eaa50397fc2aa8a7641e86 117 Pfam PF00825 Ribonuclease P 2 114 1.2E-26 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 GBCGDNIH2_RS03705 91e18659f6eaa50397fc2aa8a7641e86 117 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 1 117 14.915 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 GBCGDNIH2_RS03705 91e18659f6eaa50397fc2aa8a7641e86 117 Gene3D G3DSA:3.30.230.10 1 117 1.2E-28 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup GBCGDNIH2_RS03705 91e18659f6eaa50397fc2aa8a7641e86 117 SUPERFAMILY SSF54211 3 116 1.39E-23 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold GBCGDNIH2_RS03705 91e18659f6eaa50397fc2aa8a7641e86 117 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 7 52 0.006 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 GBCGDNIH2_RS03705 91e18659f6eaa50397fc2aa8a7641e86 117 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 3 111 4.1E-14 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 GBCGDNIH2_RS01195 caed85f88bfd7941ffb06894f229f35f 380 SUPERFAMILY SSF55347 200 310 3.79E-35 T 29-03-2018 GBCGDNIH2_RS01195 caed85f88bfd7941ffb06894f229f35f 380 Gene3D G3DSA:3.30.360.10 215 303 7.4E-35 T 29-03-2018 GBCGDNIH2_RS01195 caed85f88bfd7941ffb06894f229f35f 380 PIRSF PIRSF015578 1 376 3.6E-85 T 29-03-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 GBCGDNIH2_RS01195 caed85f88bfd7941ffb06894f229f35f 380 SUPERFAMILY SSF51735 307 364 1.52E-78 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS01195 caed85f88bfd7941ffb06894f229f35f 380 SUPERFAMILY SSF51735 5 196 1.52E-78 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS01195 caed85f88bfd7941ffb06894f229f35f 380 Gene3D G3DSA:3.40.50.720 1 214 1.0E-52 T 29-03-2018 GBCGDNIH2_RS01195 caed85f88bfd7941ffb06894f229f35f 380 Gene3D G3DSA:3.40.50.720 304 365 4.8E-14 T 29-03-2018 GBCGDNIH2_RS01195 caed85f88bfd7941ffb06894f229f35f 380 Pfam PF01658 Myo-inositol-1-phosphate synthase 202 310 7.6E-32 T 29-03-2018 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 GBCGDNIH2_RS08990 c5ce5dc99a2836c68c407fb6955b2551 438 Pfam PF01551 Peptidase family M23 334 431 5.2E-16 T 29-03-2018 IPR016047 Peptidase M23 GBCGDNIH2_RS08990 c5ce5dc99a2836c68c407fb6955b2551 438 Gene3D G3DSA:2.70.70.10 247 438 1.3E-27 T 29-03-2018 GBCGDNIH2_RS08990 c5ce5dc99a2836c68c407fb6955b2551 438 SUPERFAMILY SSF51261 245 435 2.3E-18 T 29-03-2018 IPR011055 Duplicated hybrid motif GBCGDNIH2_RS04420 cbf3c7c1f1d0eed645eb366b4aff0b14 162 Pfam PF07080 Protein of unknown function (DUF1348) 14 142 4.0E-64 T 29-03-2018 IPR009783 Protein of unknown function DUF1348 GBCGDNIH2_RS04420 cbf3c7c1f1d0eed645eb366b4aff0b14 162 Gene3D G3DSA:3.10.450.50 17 162 1.1E-65 T 29-03-2018 GBCGDNIH2_RS04420 cbf3c7c1f1d0eed645eb366b4aff0b14 162 SUPERFAMILY SSF54427 9 162 4.98E-75 T 29-03-2018 IPR032710 NTF2-like domain GBCGDNIH2_RS04390 405b68e0608b877fce7466390e5a1cf8 945 Gene3D G3DSA:3.40.50.10490 578 676 1.2E-20 T 29-03-2018 GBCGDNIH2_RS04390 405b68e0608b877fce7466390e5a1cf8 945 ProSitePatterns PS01054 Transaldolase signature 1. 44 52 - T 29-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 GBCGDNIH2_RS04390 405b68e0608b877fce7466390e5a1cf8 945 ProSitePatterns PS00958 Transaldolase active site. 141 158 - T 29-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 GBCGDNIH2_RS04390 405b68e0608b877fce7466390e5a1cf8 945 Gene3D G3DSA:3.40.50.10490 442 577 9.9E-31 T 29-03-2018 GBCGDNIH2_RS04390 405b68e0608b877fce7466390e5a1cf8 945 Gene3D G3DSA:3.40.50.10490 684 779 3.0E-12 T 29-03-2018 GBCGDNIH2_RS04390 405b68e0608b877fce7466390e5a1cf8 945 SUPERFAMILY SSF51569 6 372 2.81E-78 T 29-03-2018 GBCGDNIH2_RS04390 405b68e0608b877fce7466390e5a1cf8 945 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 19 367 8.1E-84 T 29-03-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 GBCGDNIH2_RS04390 405b68e0608b877fce7466390e5a1cf8 945 SUPERFAMILY SSF53697 344 795 1.6E-83 T 29-03-2018 GBCGDNIH2_RS04390 405b68e0608b877fce7466390e5a1cf8 945 TIGRFAM TIGR00876 tal_mycobact: transaldolase 16 365 1.1E-98 T 29-03-2018 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 GBCGDNIH2_RS04390 405b68e0608b877fce7466390e5a1cf8 945 Pfam PF00342 Phosphoglucose isomerase 458 665 5.3E-14 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GBCGDNIH2_RS04390 405b68e0608b877fce7466390e5a1cf8 945 Hamap MF_00493 Transaldolase [tal]. 1 379 125.895 T 29-03-2018 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 GBCGDNIH2_RS04390 405b68e0608b877fce7466390e5a1cf8 945 PRINTS PR00662 Glucose-6-phosphate isomerase signature 567 585 5.8E-9 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GBCGDNIH2_RS04390 405b68e0608b877fce7466390e5a1cf8 945 PRINTS PR00662 Glucose-6-phosphate isomerase signature 461 480 5.8E-9 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GBCGDNIH2_RS04390 405b68e0608b877fce7466390e5a1cf8 945 PRINTS PR00662 Glucose-6-phosphate isomerase signature 643 664 5.8E-9 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GBCGDNIH2_RS04390 405b68e0608b877fce7466390e5a1cf8 945 Gene3D G3DSA:3.20.20.70 4 370 7.0E-117 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS02990 0d224637b37f8c6a7005ff119d0cc5a6 91 SUPERFAMILY SSF54975 4 87 1.53E-24 T 29-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 GBCGDNIH2_RS02990 0d224637b37f8c6a7005ff119d0cc5a6 91 Gene3D G3DSA:3.30.70.100 1 89 1.1E-23 T 29-03-2018 GBCGDNIH2_RS02990 0d224637b37f8c6a7005ff119d0cc5a6 91 Pfam PF00708 Acylphosphatase 5 79 7.4E-23 T 29-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 GBCGDNIH2_RS02990 0d224637b37f8c6a7005ff119d0cc5a6 91 ProSitePatterns PS00151 Acylphosphatase signature 2. 32 48 - T 29-03-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 GBCGDNIH2_RS11925 d7cbdba619177bf34f5e5d61a2564307 190 SUPERFAMILY SSF69118 1 181 3.01E-44 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 GBCGDNIH2_RS11925 d7cbdba619177bf34f5e5d61a2564307 190 Gene3D G3DSA:1.20.1290.10 42 175 1.1E-22 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 GBCGDNIH2_RS11925 d7cbdba619177bf34f5e5d61a2564307 190 Gene3D G3DSA:1.20.5.810 10 41 2.3E-13 T 29-03-2018 GBCGDNIH2_RS11925 d7cbdba619177bf34f5e5d61a2564307 190 Pfam PF02627 Carboxymuconolactone decarboxylase family 53 109 2.7E-9 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 GBCGDNIH2_RS11925 d7cbdba619177bf34f5e5d61a2564307 190 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 59 103 5.6E-10 T 29-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 GBCGDNIH2_RS08800 6caf359d44e42927c6e49ac6af490f2f 77 SUPERFAMILY SSF82657 1 76 4.97E-24 T 29-03-2018 IPR002634 BolA protein GBCGDNIH2_RS08800 6caf359d44e42927c6e49ac6af490f2f 77 Pfam PF01722 BolA-like protein 27 76 1.9E-14 T 29-03-2018 IPR002634 BolA protein GBCGDNIH2_RS08800 6caf359d44e42927c6e49ac6af490f2f 77 Gene3D G3DSA:3.30.300.90 3 75 2.4E-24 T 29-03-2018 GBCGDNIH2_RS08800 6caf359d44e42927c6e49ac6af490f2f 77 PIRSF PIRSF003113 1 77 6.8E-20 T 29-03-2018 IPR002634 BolA protein GBCGDNIH2_RS02530 6476060f1722435e1cb918a110aa4417 452 Pfam PF03781 Sulfatase-modifying factor enzyme 1 221 355 6.0E-25 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 GBCGDNIH2_RS02530 6476060f1722435e1cb918a110aa4417 452 Pfam PF03781 Sulfatase-modifying factor enzyme 1 359 436 2.1E-7 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 GBCGDNIH2_RS02530 6476060f1722435e1cb918a110aa4417 452 TIGRFAM TIGR03440 egtB_TIGR03440: ergothioneine biosynthesis protein EgtB 50 435 2.3E-149 T 29-03-2018 IPR017806 Ergothioneine biosynthesis protein EgtB GO:0052699 GBCGDNIH2_RS02530 6476060f1722435e1cb918a110aa4417 452 SUPERFAMILY SSF56436 223 438 2.17E-64 T 29-03-2018 IPR016187 C-type lectin fold GBCGDNIH2_RS02530 6476060f1722435e1cb918a110aa4417 452 Gene3D G3DSA:3.90.1580.10 219 356 8.8E-32 T 29-03-2018 GBCGDNIH2_RS02530 6476060f1722435e1cb918a110aa4417 452 Gene3D G3DSA:3.90.1580.10 357 442 4.1E-19 T 29-03-2018 GBCGDNIH2_RS02530 6476060f1722435e1cb918a110aa4417 452 Pfam PF12867 DinB superfamily 53 186 4.2E-5 T 29-03-2018 IPR024775 DinB-like domain GBCGDNIH2_RS07160 e978ef509eb461176937e3aaad984e6a 931 SUPERFAMILY SSF51621 28 864 4.87E-131 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 GBCGDNIH2_RS07160 e978ef509eb461176937e3aaad984e6a 931 Pfam PF00311 Phosphoenolpyruvate carboxylase 381 548 1.1E-17 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 GBCGDNIH2_RS08370 a94bd4e25940017fc434b18182496248 325 PIRSF PIRSF029215 180 318 0.37 T 29-03-2018 IPR016913 Uncharacterised conserved protein UCP029215 GBCGDNIH2_RS08370 a94bd4e25940017fc434b18182496248 325 PIRSF PIRSF029215 11 181 9.0E-42 T 29-03-2018 IPR016913 Uncharacterised conserved protein UCP029215 GBCGDNIH2_RS08370 a94bd4e25940017fc434b18182496248 325 Pfam PF09979 Uncharacterized protein conserved in bacteria (DUF2213) 17 165 1.4E-35 T 29-03-2018 IPR016913 Uncharacterised conserved protein UCP029215 GBCGDNIH2_RS09245 4bc2985f8599f8c01b5ed8837ee3de77 554 Gene3D G3DSA:3.20.20.190 197 478 4.5E-15 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 GBCGDNIH2_RS09245 4bc2985f8599f8c01b5ed8837ee3de77 554 SUPERFAMILY SSF51695 203 243 4.19E-29 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 GBCGDNIH2_RS09245 4bc2985f8599f8c01b5ed8837ee3de77 554 SUPERFAMILY SSF51695 289 544 4.19E-29 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 GBCGDNIH2_RS11955 c2a410269ecfe85033e5a47a1279cbd9 99 Pfam PF04380 Membrane fusogenic activity 3 78 3.8E-21 T 29-03-2018 IPR007475 Membrane fusogenic activity GBCGDNIH2_RS11955 c2a410269ecfe85033e5a47a1279cbd9 99 Gene3D G3DSA:1.20.5.50 9 93 4.0E-4 T 29-03-2018 GBCGDNIH2_RS00255 9c9cd694d57b3882899d47834ef23bfc 213 SUPERFAMILY SSF101262 8 212 2.22E-59 T 29-03-2018 IPR007044 Cyclodeaminase/cyclohydrolase GO:0003824|GO:0044237 KEGG: 00340+2.1.2.5|KEGG: 00670+4.3.1.4+2.1.2.5|MetaCyc: PWY-5030|MetaCyc: PWY-5497|Reactome: R-HSA-70921 GBCGDNIH2_RS00255 9c9cd694d57b3882899d47834ef23bfc 213 Pfam PF04961 Formiminotransferase-cyclodeaminase 11 191 1.5E-65 T 29-03-2018 IPR007044 Cyclodeaminase/cyclohydrolase GO:0003824|GO:0044237 KEGG: 00340+2.1.2.5|KEGG: 00670+4.3.1.4+2.1.2.5|MetaCyc: PWY-5030|MetaCyc: PWY-5497|Reactome: R-HSA-70921 GBCGDNIH2_RS11570 8539c22930da48b77de8ae92c97fde66 219 Gene3D G3DSA:3.40.50.880 1 214 1.2E-39 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like GBCGDNIH2_RS11570 8539c22930da48b77de8ae92c97fde66 219 Pfam PF00117 Glutamine amidotransferase class-I 43 209 1.8E-15 T 29-03-2018 IPR017926 Glutamine amidotransferase GBCGDNIH2_RS11570 8539c22930da48b77de8ae92c97fde66 219 SUPERFAMILY SSF52317 3 211 2.64E-48 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like GBCGDNIH2_RS11570 8539c22930da48b77de8ae92c97fde66 219 PIRSF PIRSF000495 1 214 1.4E-59 T 29-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 GBCGDNIH2_RS11570 8539c22930da48b77de8ae92c97fde66 219 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 2 211 29.184 T 29-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 GBCGDNIH2_RS11570 8539c22930da48b77de8ae92c97fde66 219 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 3 209 1.8E-52 T 29-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 GBCGDNIH2_RS00425 53df45327d6fba507e5da14b8145c063 338 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 57 307 1.8E-48 T 29-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 GBCGDNIH2_RS00425 53df45327d6fba507e5da14b8145c063 338 TIGRFAM TIGR03414 ABC_choline_bnd: choline ABC transporter, periplasmic binding protein 49 336 1.1E-130 T 29-03-2018 IPR017783 Choline ABC transporter, substrate-binding protein GO:0015871|GO:0033265|GO:0042597 GBCGDNIH2_RS00425 53df45327d6fba507e5da14b8145c063 338 Gene3D G3DSA:3.40.190.10 50 170 3.0E-12 T 29-03-2018 GBCGDNIH2_RS00425 53df45327d6fba507e5da14b8145c063 338 Gene3D G3DSA:3.40.190.10 179 338 1.9E-32 T 29-03-2018 GBCGDNIH2_RS00425 53df45327d6fba507e5da14b8145c063 338 SUPERFAMILY SSF53850 52 324 4.7E-78 T 29-03-2018 GBCGDNIH2_RS07080 b53733e04b341fb571efe4150f58fb8f 413 SUPERFAMILY SSF53335 64 411 2.2E-43 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GBCGDNIH2_RS07080 b53733e04b341fb571efe4150f58fb8f 413 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 339 407 3.2E-8 T 29-03-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 GBCGDNIH2_RS07080 b53733e04b341fb571efe4150f58fb8f 413 Gene3D G3DSA:2.40.50.140 1 70 1.1E-13 T 29-03-2018 GBCGDNIH2_RS07080 b53733e04b341fb571efe4150f58fb8f 413 Gene3D G3DSA:3.40.50.150 71 412 6.7E-27 T 29-03-2018 GBCGDNIH2_RS07110 5939ead30ed4c7fb368fefaf7dfaf657 249 SUPERFAMILY SSF52540 2 231 2.54E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS07110 5939ead30ed4c7fb368fefaf7dfaf657 249 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 2 243 4.3E-107 T 29-03-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524|GO:0006810 GBCGDNIH2_RS07110 5939ead30ed4c7fb368fefaf7dfaf657 249 SMART SM00382 26 222 1.8E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS07110 5939ead30ed4c7fb368fefaf7dfaf657 249 Gene3D G3DSA:3.40.50.300 1 249 2.9E-40 T 29-03-2018 GBCGDNIH2_RS07110 5939ead30ed4c7fb368fefaf7dfaf657 249 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GBCGDNIH2_RS07110 5939ead30ed4c7fb368fefaf7dfaf657 249 Pfam PF00005 ABC transporter 17 172 1.7E-18 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GBCGDNIH2_RS01370 c4cc7418222b2e8ddc562ada4f25fc11 650 Pfam PF16327 Cytochrome c-type biogenesis protein CcmF C-terminal 315 635 5.8E-107 T 29-03-2018 IPR032523 Cytochrome c-type biogenesis protein CcmF, C-terminal GBCGDNIH2_RS01370 c4cc7418222b2e8ddc562ada4f25fc11 650 Pfam PF01578 Cytochrome C assembly protein 89 296 1.9E-47 T 29-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 GBCGDNIH2_RS01370 c4cc7418222b2e8ddc562ada4f25fc11 650 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 310 329 2.3E-87 T 29-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 GBCGDNIH2_RS01370 c4cc7418222b2e8ddc562ada4f25fc11 650 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 274 294 2.3E-87 T 29-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 GBCGDNIH2_RS01370 c4cc7418222b2e8ddc562ada4f25fc11 650 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 132 149 2.3E-87 T 29-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 GBCGDNIH2_RS01370 c4cc7418222b2e8ddc562ada4f25fc11 650 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 244 264 2.3E-87 T 29-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 GBCGDNIH2_RS01370 c4cc7418222b2e8ddc562ada4f25fc11 650 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 159 181 2.3E-87 T 29-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 GBCGDNIH2_RS01370 c4cc7418222b2e8ddc562ada4f25fc11 650 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 294 310 2.3E-87 T 29-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 GBCGDNIH2_RS01370 c4cc7418222b2e8ddc562ada4f25fc11 650 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 80 106 2.3E-87 T 29-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 GBCGDNIH2_RS01370 c4cc7418222b2e8ddc562ada4f25fc11 650 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 210 236 2.3E-87 T 29-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 GBCGDNIH2_RS01370 c4cc7418222b2e8ddc562ada4f25fc11 650 TIGRFAM TIGR00353 nrfE: cytochrome c-type biogenesis protein CcmF 53 638 2.6E-182 T 29-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 GBCGDNIH2_RS01370 c4cc7418222b2e8ddc562ada4f25fc11 650 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 113 136 4.2E-51 T 29-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 GBCGDNIH2_RS01370 c4cc7418222b2e8ddc562ada4f25fc11 650 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 628 641 4.2E-51 T 29-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 GBCGDNIH2_RS01370 c4cc7418222b2e8ddc562ada4f25fc11 650 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 351 368 4.2E-51 T 29-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 GBCGDNIH2_RS01370 c4cc7418222b2e8ddc562ada4f25fc11 650 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 189 204 4.2E-51 T 29-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 GBCGDNIH2_RS01370 c4cc7418222b2e8ddc562ada4f25fc11 650 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 313 328 4.2E-51 T 29-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 GBCGDNIH2_RS01370 c4cc7418222b2e8ddc562ada4f25fc11 650 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 4 28 4.2E-51 T 29-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 GBCGDNIH2_RS01370 c4cc7418222b2e8ddc562ada4f25fc11 650 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 394 413 4.2E-51 T 29-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 GBCGDNIH2_RS06765 86bdb4c791f2cefc6c28cbbff803b545 348 Gene3D G3DSA:3.20.20.300 1 313 1.3E-50 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 GBCGDNIH2_RS06765 86bdb4c791f2cefc6c28cbbff803b545 348 SUPERFAMILY SSF51445 3 289 4.21E-64 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily GBCGDNIH2_RS06765 86bdb4c791f2cefc6c28cbbff803b545 348 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 238 255 - T 29-03-2018 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 GBCGDNIH2_RS06765 86bdb4c791f2cefc6c28cbbff803b545 348 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 17 293 3.7E-41 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 GBCGDNIH2_RS02495 535487f5ff64d3b45bba3ff6dc93df3f 154 SUPERFAMILY SSF82784 1 147 5.23E-41 T 29-03-2018 IPR003718 OsmC/Ohr family GBCGDNIH2_RS02495 535487f5ff64d3b45bba3ff6dc93df3f 154 Gene3D G3DSA:3.30.300.20 1 152 2.2E-36 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta GBCGDNIH2_RS02495 535487f5ff64d3b45bba3ff6dc93df3f 154 Pfam PF02566 OsmC-like protein 49 145 4.7E-13 T 29-03-2018 IPR003718 OsmC/Ohr family GBCGDNIH2_RS03035 57c234a041ce8559562d35fda519002b 294 Gene3D G3DSA:3.40.50.150 38 271 4.0E-23 T 29-03-2018 GBCGDNIH2_RS03035 57c234a041ce8559562d35fda519002b 294 Pfam PF13489 Methyltransferase domain 38 191 1.8E-13 T 29-03-2018 GBCGDNIH2_RS03035 57c234a041ce8559562d35fda519002b 294 SUPERFAMILY SSF53335 34 228 3.9E-26 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GBCGDNIH2_RS02620 31af8b78fa640ced916b049e0dedeac2 432 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 11 429 1.9E-121 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 GBCGDNIH2_RS02620 31af8b78fa640ced916b049e0dedeac2 432 PIRSF PIRSF001434 1 432 8.2E-118 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 GBCGDNIH2_RS02620 31af8b78fa640ced916b049e0dedeac2 432 Gene3D G3DSA:3.40.640.10 8 296 1.8E-53 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GBCGDNIH2_RS02620 31af8b78fa640ced916b049e0dedeac2 432 SUPERFAMILY SSF53383 9 430 1.53E-111 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase GBCGDNIH2_RS02620 31af8b78fa640ced916b049e0dedeac2 432 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 10 430 9.2E-178 T 29-03-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 GBCGDNIH2_RS02620 31af8b78fa640ced916b049e0dedeac2 432 Gene3D G3DSA:3.90.1150.10 298 431 1.1E-41 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 GBCGDNIH2_RS09965 44a4924c7a1d60e7f4f6234da666a4a9 801 Pfam PF07715 TonB-dependent Receptor Plug Domain 68 178 4.8E-7 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 GBCGDNIH2_RS09965 44a4924c7a1d60e7f4f6234da666a4a9 801 Pfam PF00593 TonB dependent receptor 293 782 2.0E-37 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 GBCGDNIH2_RS09965 44a4924c7a1d60e7f4f6234da666a4a9 801 Gene3D G3DSA:2.40.170.20 191 801 4.1E-76 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 GBCGDNIH2_RS09965 44a4924c7a1d60e7f4f6234da666a4a9 801 SUPERFAMILY SSF56935 48 801 1.88E-88 T 29-03-2018 GBCGDNIH2_RS09965 44a4924c7a1d60e7f4f6234da666a4a9 801 Gene3D G3DSA:2.170.130.10 65 190 3.0E-10 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 GBCGDNIH2_RS02350 28e0199c42208eba15ccfb1e2c74bd9b 178 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 34 130 2.0E-24 T 29-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain GBCGDNIH2_RS02350 28e0199c42208eba15ccfb1e2c74bd9b 178 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 36 178 43.505 T 29-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 GBCGDNIH2_RS02350 28e0199c42208eba15ccfb1e2c74bd9b 178 SUPERFAMILY SSF53927 35 178 1.36E-49 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 GBCGDNIH2_RS02350 28e0199c42208eba15ccfb1e2c74bd9b 178 Gene3D G3DSA:3.40.140.10 33 178 4.2E-47 T 29-03-2018 GBCGDNIH2_RS03760 d6bd46429a2ecef8b954aae2ae722b3e 323 SUPERFAMILY SSF51735 3 321 1.93E-80 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS03760 d6bd46429a2ecef8b954aae2ae722b3e 323 Gene3D G3DSA:3.40.50.720 2 198 1.3E-33 T 29-03-2018 GBCGDNIH2_RS03760 d6bd46429a2ecef8b954aae2ae722b3e 323 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 250 2.0E-50 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 GBCGDNIH2_RS03760 d6bd46429a2ecef8b954aae2ae722b3e 323 Gene3D G3DSA:3.90.25.10 199 323 4.4E-33 T 29-03-2018 GBCGDNIH2_RS03760 d6bd46429a2ecef8b954aae2ae722b3e 323 PRINTS PR01713 Nucleotide sugar epimerase signature 244 259 1.4E-23 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 GBCGDNIH2_RS03760 d6bd46429a2ecef8b954aae2ae722b3e 323 PRINTS PR01713 Nucleotide sugar epimerase signature 29 45 1.4E-23 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 GBCGDNIH2_RS03760 d6bd46429a2ecef8b954aae2ae722b3e 323 PRINTS PR01713 Nucleotide sugar epimerase signature 218 233 1.4E-23 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 GBCGDNIH2_RS03760 d6bd46429a2ecef8b954aae2ae722b3e 323 PRINTS PR01713 Nucleotide sugar epimerase signature 283 300 1.4E-23 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 GBCGDNIH2_RS00825 1fe14ab3ea0f69c6f5377a2c501aaabf 651 Gene3D G3DSA:3.40.50.720 145 278 6.2E-13 T 29-03-2018 GBCGDNIH2_RS00825 1fe14ab3ea0f69c6f5377a2c501aaabf 651 Gene3D G3DSA:3.40.50.720 291 630 3.7E-57 T 29-03-2018 GBCGDNIH2_RS00825 1fe14ab3ea0f69c6f5377a2c501aaabf 651 SUPERFAMILY SSF51735 294 573 4.35E-54 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS00825 1fe14ab3ea0f69c6f5377a2c501aaabf 651 Pfam PF02719 Polysaccharide biosynthesis protein 297 592 1.4E-104 T 29-03-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain GBCGDNIH2_RS11835 8e73adbb815440592eac04aebbb39d04 616 Gene3D G3DSA:3.90.980.10 103 236 2.6E-36 T 29-03-2018 IPR013264 DNA primase, catalytic core, N-terminal GBCGDNIH2_RS11835 8e73adbb815440592eac04aebbb39d04 616 SUPERFAMILY SSF56731 111 418 1.02E-90 T 29-03-2018 GBCGDNIH2_RS11835 8e73adbb815440592eac04aebbb39d04 616 Gene3D G3DSA:3.40.1360.10 237 364 1.5E-30 T 29-03-2018 GBCGDNIH2_RS11835 8e73adbb815440592eac04aebbb39d04 616 Pfam PF08275 DNA primase catalytic core, N-terminal domain 120 247 5.4E-34 T 29-03-2018 IPR013264 DNA primase, catalytic core, N-terminal GBCGDNIH2_RS11835 8e73adbb815440592eac04aebbb39d04 616 Gene3D G3DSA:3.90.580.10 1 99 1.3E-30 T 29-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 GBCGDNIH2_RS11835 8e73adbb815440592eac04aebbb39d04 616 SMART SM00400 34 86 4.4E-26 T 29-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 GBCGDNIH2_RS11835 8e73adbb815440592eac04aebbb39d04 616 Pfam PF01807 CHC2 zinc finger 5 95 7.9E-32 T 29-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 GBCGDNIH2_RS11835 8e73adbb815440592eac04aebbb39d04 616 SMART SM00493 255 326 7.6E-10 T 29-03-2018 IPR006171 TOPRIM domain GBCGDNIH2_RS11835 8e73adbb815440592eac04aebbb39d04 616 TIGRFAM TIGR01391 dnaG: DNA primase 4 417 8.0E-125 T 29-03-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 GBCGDNIH2_RS11835 8e73adbb815440592eac04aebbb39d04 616 Hamap MF_00974 DNA primase [dnaG]. 2 601 24.325 T 29-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 GBCGDNIH2_RS11835 8e73adbb815440592eac04aebbb39d04 616 SUPERFAMILY SSF57783 2 96 3.4E-32 T 29-03-2018 GBCGDNIH2_RS11835 8e73adbb815440592eac04aebbb39d04 616 Pfam PF13662 Toprim domain 258 323 9.9E-16 T 29-03-2018 IPR006171 TOPRIM domain GBCGDNIH2_RS02085 62c4d08c547d58ebb15cb46864611128 758 Pfam PF13515 Fusaric acid resistance protein-like 434 557 1.4E-21 T 29-03-2018 GBCGDNIH2_RS03750 26cad37d7991040577dee19a7646ebf8 325 SUPERFAMILY SSF53633 38 324 2.36E-91 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase GBCGDNIH2_RS03750 26cad37d7991040577dee19a7646ebf8 325 PRINTS PR00474 Glutamate 5-kinase family signature 275 295 8.0E-7 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 GBCGDNIH2_RS03750 26cad37d7991040577dee19a7646ebf8 325 PRINTS PR00474 Glutamate 5-kinase family signature 225 252 8.0E-7 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 GBCGDNIH2_RS03750 26cad37d7991040577dee19a7646ebf8 325 PRINTS PR00474 Glutamate 5-kinase family signature 87 101 8.0E-7 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 GBCGDNIH2_RS03750 26cad37d7991040577dee19a7646ebf8 325 Hamap MF_00082_B Acetylglutamate kinase [argB]. 54 325 36.774 T 29-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 GBCGDNIH2_RS03750 26cad37d7991040577dee19a7646ebf8 325 Pfam PF00696 Amino acid kinase family 57 301 1.5E-46 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase GBCGDNIH2_RS03750 26cad37d7991040577dee19a7646ebf8 325 PIRSF PIRSF000728 37 325 7.6E-107 T 29-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 GBCGDNIH2_RS03750 26cad37d7991040577dee19a7646ebf8 325 Gene3D G3DSA:3.40.1160.10 9 325 4.0E-72 T 29-03-2018 GBCGDNIH2_RS03750 26cad37d7991040577dee19a7646ebf8 325 TIGRFAM TIGR00761 argB: acetylglutamate kinase 57 300 2.5E-75 T 29-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 GBCGDNIH2_RS06130 220e99e5b3687a31f4be080684d15a48 2741 SMART SM00710 915 936 7100.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat GBCGDNIH2_RS06130 220e99e5b3687a31f4be080684d15a48 2741 SMART SM00710 2245 2269 8200.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat GBCGDNIH2_RS06130 220e99e5b3687a31f4be080684d15a48 2741 SMART SM00710 1749 1771 5300.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat GBCGDNIH2_RS06130 220e99e5b3687a31f4be080684d15a48 2741 SMART SM00710 192 223 1400.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat GBCGDNIH2_RS06130 220e99e5b3687a31f4be080684d15a48 2741 SMART SM00710 2141 2162 3700.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat GBCGDNIH2_RS06130 220e99e5b3687a31f4be080684d15a48 2741 SMART SM00710 1659 1690 2500.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat GBCGDNIH2_RS06130 220e99e5b3687a31f4be080684d15a48 2741 SMART SM00710 1297 1319 740.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat GBCGDNIH2_RS06130 220e99e5b3687a31f4be080684d15a48 2741 SMART SM00710 534 555 9100.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat GBCGDNIH2_RS06130 220e99e5b3687a31f4be080684d15a48 2741 SMART SM00710 487 508 7800.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat GBCGDNIH2_RS06130 220e99e5b3687a31f4be080684d15a48 2741 SMART SM00710 1720 1742 560.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat GBCGDNIH2_RS06130 220e99e5b3687a31f4be080684d15a48 2741 Pfam PF13403 Hint domain 2534 2669 6.5E-47 T 29-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 GBCGDNIH2_RS06130 220e99e5b3687a31f4be080684d15a48 2741 Gene3D G3DSA:2.170.16.10 2527 2740 1.4E-17 T 29-03-2018 GBCGDNIH2_RS06130 220e99e5b3687a31f4be080684d15a48 2741 SUPERFAMILY SSF51294 2535 2667 1.2E-12 T 29-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 GBCGDNIH2_RS11235 65e208808ce8d041c0077308007f6176 101 Hamap MF_01954 Urease subunit beta [ureB]. 1 101 30.176 T 29-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 GBCGDNIH2_RS11235 65e208808ce8d041c0077308007f6176 101 SUPERFAMILY SSF51278 1 98 1.7E-44 T 29-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 GBCGDNIH2_RS11235 65e208808ce8d041c0077308007f6176 101 TIGRFAM TIGR00192 urease_beta: urease, beta subunit 1 96 6.6E-39 T 29-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 GBCGDNIH2_RS11235 65e208808ce8d041c0077308007f6176 101 Gene3D G3DSA:2.10.150.10 1 101 1.4E-43 T 29-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 GBCGDNIH2_RS11235 65e208808ce8d041c0077308007f6176 101 Pfam PF00699 Urease beta subunit 3 97 2.5E-41 T 29-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 GBCGDNIH2_RS08560 089c98b1bd6745219f5f308a5ddb7718 355 Gene3D G3DSA:3.30.460.20 31 153 1.7E-7 T 29-03-2018 GBCGDNIH2_RS08560 089c98b1bd6745219f5f308a5ddb7718 355 Pfam PF01544 CorA-like Mg2+ transporter protein 61 339 1.8E-42 T 29-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 GBCGDNIH2_RS08560 089c98b1bd6745219f5f308a5ddb7718 355 SUPERFAMILY SSF144083 281 342 7.06E-14 T 29-03-2018 GBCGDNIH2_RS08560 089c98b1bd6745219f5f308a5ddb7718 355 Gene3D G3DSA:1.20.58.340 163 279 2.4E-8 T 29-03-2018 GBCGDNIH2_RS08560 089c98b1bd6745219f5f308a5ddb7718 355 Gene3D G3DSA:1.20.58.340 280 346 1.2E-12 T 29-03-2018 GBCGDNIH2_RS08560 089c98b1bd6745219f5f308a5ddb7718 355 SUPERFAMILY SSF143865 39 265 1.22E-20 T 29-03-2018 GBCGDNIH2_RS07430 914b52e0f34fa22e175850d98714f6a3 362 Gene3D G3DSA:3.40.50.10470 142 352 1.7E-60 T 29-03-2018 GBCGDNIH2_RS07430 914b52e0f34fa22e175850d98714f6a3 362 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 39 344 6.7E-95 T 29-03-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 GBCGDNIH2_RS07430 914b52e0f34fa22e175850d98714f6a3 362 SUPERFAMILY SSF100950 1 350 7.18E-114 T 29-03-2018 GBCGDNIH2_RS07430 914b52e0f34fa22e175850d98714f6a3 362 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 7 357 37.06 T 29-03-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 GBCGDNIH2_RS07430 914b52e0f34fa22e175850d98714f6a3 362 Gene3D G3DSA:1.20.120.420 8 141 2.3E-42 T 29-03-2018 IPR027363 Methylthioribose-1-phosphate isomerase-like, N-terminal domain KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 GBCGDNIH2_RS07430 914b52e0f34fa22e175850d98714f6a3 362 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 18 347 3.5E-127 T 29-03-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 GBCGDNIH2_RS07430 914b52e0f34fa22e175850d98714f6a3 362 Pfam PF01008 Initiation factor 2 subunit family 51 345 2.1E-60 T 29-03-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 GBCGDNIH2_RS10200 5795854c80cc2937bc4a9ce29ac52094 289 Hamap MF_01207 Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ [msrQ]. 6 201 18.198 T 29-03-2018 IPR022837 Protein-methionine-sulfoxide reductase subunit MsrQ GO:0005887|GO:0030091 GBCGDNIH2_RS10200 5795854c80cc2937bc4a9ce29ac52094 289 Pfam PF01794 Ferric reductase like transmembrane component 50 161 4.0E-15 T 29-03-2018 IPR013130 Ferric reductase transmembrane component-like domain GBCGDNIH2_RS12685 d2101faa6429c3a708d646436904d954 101 Hamap MF_00656 Coenzyme PQQ synthesis protein A [pqqA]. 79 101 10.602 T 29-03-2018 IPR011725 Coenzyme PQQ biosynthesis protein A GO:0018189 GBCGDNIH2_RS12685 d2101faa6429c3a708d646436904d954 101 Pfam PF08042 PqqA family 79 97 1.3E-6 T 29-03-2018 IPR011725 Coenzyme PQQ biosynthesis protein A GO:0018189 GBCGDNIH2_RS12685 d2101faa6429c3a708d646436904d954 101 TIGRFAM TIGR02107 PQQ_syn_pqqA: coenzyme PQQ precursor peptide PqqA 80 100 5.0E-9 T 29-03-2018 IPR011725 Coenzyme PQQ biosynthesis protein A GO:0018189 GBCGDNIH2_RS01460 7f51b8821c2c86e9e35a8b09bec4c17f 183 Gene3D G3DSA:1.20.910.10 1 181 1.3E-26 T 29-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 GBCGDNIH2_RS01460 7f51b8821c2c86e9e35a8b09bec4c17f 183 Pfam PF01126 Heme oxygenase 4 176 5.8E-6 T 29-03-2018 IPR016053 Haem oxygenase-like GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 GBCGDNIH2_RS01460 7f51b8821c2c86e9e35a8b09bec4c17f 183 SUPERFAMILY SSF48613 5 180 1.26E-36 T 29-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 GBCGDNIH2_RS05445 031891f4784da6291bf321963ece5965 207 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 195 1.4E-60 T 29-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 GBCGDNIH2_RS05445 031891f4784da6291bf321963ece5965 207 Gene3D G3DSA:2.40.30.20 97 194 2.5E-35 T 29-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 GBCGDNIH2_RS05445 031891f4784da6291bf321963ece5965 207 SUPERFAMILY SSF63380 97 196 5.36E-34 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 GBCGDNIH2_RS05445 031891f4784da6291bf321963ece5965 207 Gene3D G3DSA:2.40.30.20 1 96 9.1E-26 T 29-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 GBCGDNIH2_RS05445 031891f4784da6291bf321963ece5965 207 SUPERFAMILY SSF63380 1 96 1.7E-22 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 GBCGDNIH2_RS05445 031891f4784da6291bf321963ece5965 207 PIRSF PIRSF000498 1 205 9.0E-71 T 29-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 GBCGDNIH2_RS05445 031891f4784da6291bf321963ece5965 207 Pfam PF00677 Lumazine binding domain 103 187 1.0E-24 T 29-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 GBCGDNIH2_RS05445 031891f4784da6291bf321963ece5965 207 Pfam PF00677 Lumazine binding domain 3 90 7.3E-19 T 29-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 GBCGDNIH2_RS02870 e2584951e490eb2449f3f18da8700b0d 138 SUPERFAMILY SSF54686 1 134 1.09E-56 T 29-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 GBCGDNIH2_RS02870 e2584951e490eb2449f3f18da8700b0d 138 PRINTS PR00060 Ribosomal protein L16 signature 88 117 4.4E-40 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS02870 e2584951e490eb2449f3f18da8700b0d 138 PRINTS PR00060 Ribosomal protein L16 signature 42 53 4.4E-40 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS02870 e2584951e490eb2449f3f18da8700b0d 138 PRINTS PR00060 Ribosomal protein L16 signature 24 36 4.4E-40 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS02870 e2584951e490eb2449f3f18da8700b0d 138 PRINTS PR00060 Ribosomal protein L16 signature 58 87 4.4E-40 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS02870 e2584951e490eb2449f3f18da8700b0d 138 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 39.242 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS02870 e2584951e490eb2449f3f18da8700b0d 138 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 29-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS02870 e2584951e490eb2449f3f18da8700b0d 138 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 1.7E-58 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS02870 e2584951e490eb2449f3f18da8700b0d 138 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 6.4E-51 T 29-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 GBCGDNIH2_RS02870 e2584951e490eb2449f3f18da8700b0d 138 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 29-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS02870 e2584951e490eb2449f3f18da8700b0d 138 Gene3D G3DSA:3.90.1170.10 1 138 4.9E-53 T 29-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 GBCGDNIH2_RS07155 f878ffd177cb5d5ff23bec4369d6552e 280 Pfam PF14023 Protein of unknown function (DUF4239) 82 264 1.1E-11 T 29-03-2018 IPR025333 Protein of unknown function DUF4239 GBCGDNIH2_RS11940 c8bbc9e9fe2f90e7217d17877447be7a 224 SUPERFAMILY SSF46689 3 67 2.98E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 GBCGDNIH2_RS11940 c8bbc9e9fe2f90e7217d17877447be7a 224 Gene3D G3DSA:1.10.357.10 4 217 2.1E-11 T 29-03-2018 GBCGDNIH2_RS09570 d1ba38620268ba209f950b2662b52950 324 Gene3D G3DSA:3.10.20.30 230 324 7.4E-18 T 29-03-2018 IPR012675 Beta-grasp domain GBCGDNIH2_RS09570 d1ba38620268ba209f950b2662b52950 324 SUPERFAMILY SSF52343 116 240 3.93E-21 T 29-03-2018 GBCGDNIH2_RS09570 d1ba38620268ba209f950b2662b52950 324 Gene3D G3DSA:3.40.50.80 113 229 2.8E-15 T 29-03-2018 GBCGDNIH2_RS09570 d1ba38620268ba209f950b2662b52950 324 Pfam PF00970 Oxidoreductase FAD-binding domain 13 107 8.1E-6 T 29-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 GBCGDNIH2_RS09570 d1ba38620268ba209f950b2662b52950 324 SUPERFAMILY SSF63380 8 106 3.4E-18 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 GBCGDNIH2_RS09570 d1ba38620268ba209f950b2662b52950 324 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 273 281 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 GBCGDNIH2_RS09570 d1ba38620268ba209f950b2662b52950 324 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 248 315 1.1E-11 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 GBCGDNIH2_RS09570 d1ba38620268ba209f950b2662b52950 324 PRINTS PR00409 Phthalate dioxygenase reductase family signature 98 112 4.6E-16 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 GBCGDNIH2_RS09570 d1ba38620268ba209f950b2662b52950 324 PRINTS PR00409 Phthalate dioxygenase reductase family signature 198 206 4.6E-16 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 GBCGDNIH2_RS09570 d1ba38620268ba209f950b2662b52950 324 PRINTS PR00409 Phthalate dioxygenase reductase family signature 145 154 4.6E-16 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 GBCGDNIH2_RS09570 d1ba38620268ba209f950b2662b52950 324 PRINTS PR00409 Phthalate dioxygenase reductase family signature 45 57 4.6E-16 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 GBCGDNIH2_RS09570 d1ba38620268ba209f950b2662b52950 324 PRINTS PR00409 Phthalate dioxygenase reductase family signature 120 139 4.6E-16 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 GBCGDNIH2_RS09570 d1ba38620268ba209f950b2662b52950 324 Gene3D G3DSA:2.40.30.10 1 109 2.6E-14 T 29-03-2018 GBCGDNIH2_RS09570 d1ba38620268ba209f950b2662b52950 324 SUPERFAMILY SSF54292 220 324 1.48E-22 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 GBCGDNIH2_RS06395 1aa6c5043205c19e6f98a6977b4939de 156 Pfam PF00583 Acetyltransferase (GNAT) family 20 133 4.3E-17 T 29-03-2018 IPR000182 GNAT domain GO:0008080 GBCGDNIH2_RS06395 1aa6c5043205c19e6f98a6977b4939de 156 Gene3D G3DSA:3.40.630.30 1 155 1.2E-28 T 29-03-2018 GBCGDNIH2_RS06395 1aa6c5043205c19e6f98a6977b4939de 156 SUPERFAMILY SSF55729 2 146 1.24E-32 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase GBCGDNIH2_RS03415 20c19f9ce1a05dc44a48a1bda79a41ec 381 Gene3D G3DSA:1.10.1610.10 55 118 4.5E-25 T 29-03-2018 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 GBCGDNIH2_RS03415 20c19f9ce1a05dc44a48a1bda79a41ec 381 SUPERFAMILY SSF52733 60 373 1.96E-99 T 29-03-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 GBCGDNIH2_RS03415 20c19f9ce1a05dc44a48a1bda79a41ec 381 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 62 373 2.9E-110 T 29-03-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 GBCGDNIH2_RS03415 20c19f9ce1a05dc44a48a1bda79a41ec 381 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 60 375 32.895 T 29-03-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 GBCGDNIH2_RS03415 20c19f9ce1a05dc44a48a1bda79a41ec 381 Gene3D G3DSA:3.40.50.10210 119 356 6.2E-81 T 29-03-2018 GBCGDNIH2_RS03415 20c19f9ce1a05dc44a48a1bda79a41ec 381 Pfam PF02277 Phosphoribosyltransferase 62 373 4.3E-109 T 29-03-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 GBCGDNIH2_RS09800 0fcfd2075c33328c1b895bdbabe5d817 280 Gene3D G3DSA:2.160.10.20 185 279 8.7E-21 T 29-03-2018 GBCGDNIH2_RS09800 0fcfd2075c33328c1b895bdbabe5d817 280 Gene3D G3DSA:2.160.10.20 127 184 7.0E-6 T 29-03-2018 GBCGDNIH2_RS09800 0fcfd2075c33328c1b895bdbabe5d817 280 Gene3D G3DSA:2.160.10.20 45 126 2.4E-16 T 29-03-2018 GBCGDNIH2_RS09800 0fcfd2075c33328c1b895bdbabe5d817 280 SUPERFAMILY SSF141571 56 260 1.18E-33 T 29-03-2018 GBCGDNIH2_RS09800 0fcfd2075c33328c1b895bdbabe5d817 280 Pfam PF00805 Pentapeptide repeats (8 copies) 75 111 1.4E-10 T 29-03-2018 IPR001646 Pentapeptide repeat GBCGDNIH2_RS09800 0fcfd2075c33328c1b895bdbabe5d817 280 Pfam PF00805 Pentapeptide repeats (8 copies) 221 260 3.8E-11 T 29-03-2018 IPR001646 Pentapeptide repeat GBCGDNIH2_RS07095 76e921e5bbec5704bf455e2a2e5f0272 156 SUPERFAMILY SSF82649 3 152 1.54E-33 T 29-03-2018 GBCGDNIH2_RS07095 76e921e5bbec5704bf455e2a2e5f0272 156 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 7 151 1.4E-31 T 29-03-2018 GBCGDNIH2_RS07095 76e921e5bbec5704bf455e2a2e5f0272 156 Pfam PF01592 NifU-like N terminal domain 10 98 1.4E-10 T 29-03-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 GBCGDNIH2_RS07095 76e921e5bbec5704bf455e2a2e5f0272 156 Gene3D G3DSA:3.90.1010.10 3 152 1.4E-32 T 29-03-2018 GBCGDNIH2_RS12475 57f7dd61c9d5c715074a8468c485c27c 393 Pfam PF13394 4Fe-4S single cluster domain 37 112 5.6E-5 T 29-03-2018 GBCGDNIH2_RS12475 57f7dd61c9d5c715074a8468c485c27c 393 Pfam PF11946 Domain of unknown function (DUF3463) 195 330 2.0E-60 T 29-03-2018 IPR022563 Domain of unknown function DUF3463 GBCGDNIH2_RS12475 57f7dd61c9d5c715074a8468c485c27c 393 Gene3D G3DSA:3.20.20.70 17 343 3.8E-29 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS12475 57f7dd61c9d5c715074a8468c485c27c 393 TIGRFAM TIGR03470 HpnH: hopanoid biosynthesis associated radical SAM protein HpnH 1 319 1.5E-164 T 29-03-2018 IPR017833 Hopanoid biosynthesis associated radical SAM protein HpnH GBCGDNIH2_RS12475 57f7dd61c9d5c715074a8468c485c27c 393 Pfam PF04055 Radical SAM superfamily 34 182 1.8E-14 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 GBCGDNIH2_RS12475 57f7dd61c9d5c715074a8468c485c27c 393 SUPERFAMILY SSF102114 24 309 6.8E-52 T 29-03-2018 GBCGDNIH2_RS09890 8f53e3af9f588f291391363be8ad2174 266 Pfam PF05985 Ethanolamine ammonia-lyase light chain (EutC) 19 246 1.1E-89 T 29-03-2018 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 GBCGDNIH2_RS09890 8f53e3af9f588f291391363be8ad2174 266 PIRSF PIRSF018982 3 254 9.3E-93 T 29-03-2018 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 GBCGDNIH2_RS12330 6d68ce7e6aeed7bf6ad271e7f8e94294 628 Pfam PF06276 Ferric iron reductase FhuF-like transporter 425 580 2.6E-35 T 29-03-2018 IPR022770 Ferric iron reductase FhuF domain GBCGDNIH2_RS12330 6d68ce7e6aeed7bf6ad271e7f8e94294 628 Pfam PF04183 IucA / IucC family 159 401 3.6E-64 T 29-03-2018 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0015343|GO:0019290 GBCGDNIH2_RS04760 9ad193250e8f38cd07d55e45afb007fa 281 Gene3D G3DSA:1.10.443.10 110 278 9.6E-40 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 GBCGDNIH2_RS04760 9ad193250e8f38cd07d55e45afb007fa 281 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 25 84 8.1E-5 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 GBCGDNIH2_RS04760 9ad193250e8f38cd07d55e45afb007fa 281 Gene3D G3DSA:1.10.150.130 8 109 1.9E-11 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal GBCGDNIH2_RS04760 9ad193250e8f38cd07d55e45afb007fa 281 SUPERFAMILY SSF56349 15 271 5.59E-44 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 GBCGDNIH2_RS04760 9ad193250e8f38cd07d55e45afb007fa 281 Pfam PF00589 Phage integrase family 111 270 6.5E-32 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 GBCGDNIH2_RS03105 cbb1e9825a86da98413f54bb127582ac 261 SUPERFAMILY SSF53335 14 259 2.41E-44 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GBCGDNIH2_RS03105 cbb1e9825a86da98413f54bb127582ac 261 Pfam PF08241 Methyltransferase domain 52 148 2.4E-24 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 GBCGDNIH2_RS03105 cbb1e9825a86da98413f54bb127582ac 261 Gene3D G3DSA:3.40.50.150 33 234 1.8E-44 T 29-03-2018 GBCGDNIH2_RS04980 385460b330813e8b30db1c7089725ce5 337 SUPERFAMILY SSF55298 205 332 1.35E-12 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like GBCGDNIH2_RS04980 385460b330813e8b30db1c7089725ce5 337 Gene3D G3DSA:3.30.1330.40 198 335 1.6E-20 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like GBCGDNIH2_RS09725 0db0749ebe588665c5523817a4ec3c47 379 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 35 41 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 GBCGDNIH2_RS09725 0db0749ebe588665c5523817a4ec3c47 379 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 195 212 3.3E-36 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 GBCGDNIH2_RS09725 0db0749ebe588665c5523817a4ec3c47 379 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 31 45 3.3E-36 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 GBCGDNIH2_RS09725 0db0749ebe588665c5523817a4ec3c47 379 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 214 232 3.3E-36 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 GBCGDNIH2_RS09725 0db0749ebe588665c5523817a4ec3c47 379 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 80 100 3.3E-36 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 GBCGDNIH2_RS09725 0db0749ebe588665c5523817a4ec3c47 379 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 237 257 3.3E-36 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 GBCGDNIH2_RS09725 0db0749ebe588665c5523817a4ec3c47 379 Pfam PF01555 DNA methylase 32 252 8.3E-50 T 29-03-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 GBCGDNIH2_RS09725 0db0749ebe588665c5523817a4ec3c47 379 SUPERFAMILY SSF53335 9 257 1.11E-67 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GBCGDNIH2_RS09725 0db0749ebe588665c5523817a4ec3c47 379 Gene3D G3DSA:3.40.50.150 11 272 2.5E-55 T 29-03-2018 GBCGDNIH2_RS01860 35865617598a74743367e572934534d0 361 Gene3D G3DSA:2.40.160.20 5 245 6.8E-28 T 29-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 GBCGDNIH2_RS01860 35865617598a74743367e572934534d0 361 Gene3D G3DSA:3.30.1330.60 246 361 2.1E-31 T 29-03-2018 IPR006665 OmpA-like domain GBCGDNIH2_RS01860 35865617598a74743367e572934534d0 361 SUPERFAMILY SSF56925 24 233 3.66E-22 T 29-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 GBCGDNIH2_RS01860 35865617598a74743367e572934534d0 361 Pfam PF00691 OmpA family 259 354 2.0E-17 T 29-03-2018 IPR006665 OmpA-like domain GBCGDNIH2_RS01860 35865617598a74743367e572934534d0 361 Pfam PF13505 Outer membrane protein beta-barrel domain 6 233 7.9E-17 T 29-03-2018 IPR027385 Outer membrane protein beta-barrel GBCGDNIH2_RS01860 35865617598a74743367e572934534d0 361 PRINTS PR01021 OMPA domain signature 305 321 4.8E-11 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 GBCGDNIH2_RS01860 35865617598a74743367e572934534d0 361 PRINTS PR01021 OMPA domain signature 290 305 4.8E-11 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 GBCGDNIH2_RS01860 35865617598a74743367e572934534d0 361 PRINTS PR01021 OMPA domain signature 260 282 4.8E-11 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 GBCGDNIH2_RS01860 35865617598a74743367e572934534d0 361 SUPERFAMILY SSF103088 255 360 2.75E-30 T 29-03-2018 IPR006665 OmpA-like domain GBCGDNIH2_RS11170 159ca16cb3e59cd1d68aea469721600d 429 Gene3D G3DSA:1.20.1250.20 232 429 4.0E-22 T 29-03-2018 GBCGDNIH2_RS11170 159ca16cb3e59cd1d68aea469721600d 429 Gene3D G3DSA:1.20.1250.20 33 211 1.3E-19 T 29-03-2018 GBCGDNIH2_RS11170 159ca16cb3e59cd1d68aea469721600d 429 SUPERFAMILY SSF103473 40 428 4.71E-46 T 29-03-2018 IPR020846 Major facilitator superfamily domain GBCGDNIH2_RS11170 159ca16cb3e59cd1d68aea469721600d 429 Pfam PF07690 Major Facilitator Superfamily 44 324 3.1E-26 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 GBCGDNIH2_RS09475 869aea66625e6105b82913532e1c782a 310 TIGRFAM TIGR02170 thyX: thymidylate synthase, flavin-dependent 44 258 1.9E-60 T 29-03-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 GBCGDNIH2_RS09475 869aea66625e6105b82913532e1c782a 310 Hamap MF_01408 Flavin-dependent thymidylate synthase [thyX]. 40 266 27.625 T 29-03-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 GBCGDNIH2_RS09475 869aea66625e6105b82913532e1c782a 310 SUPERFAMILY SSF69796 36 265 5.36E-65 T 29-03-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 GBCGDNIH2_RS09475 869aea66625e6105b82913532e1c782a 310 Pfam PF02511 Thymidylate synthase complementing protein 46 252 4.4E-54 T 29-03-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 GBCGDNIH2_RS11815 dad87ed83a33701945933c96964ec63d 495 Pfam PF12710 haloacid dehalogenase-like hydrolase 26 165 2.7E-10 T 29-03-2018 GBCGDNIH2_RS11815 dad87ed83a33701945933c96964ec63d 495 Gene3D G3DSA:3.40.50.1000 25 197 1.0E-9 T 29-03-2018 IPR023214 HAD-like domain GBCGDNIH2_RS11815 dad87ed83a33701945933c96964ec63d 495 Pfam PF01040 UbiA prenyltransferase family 235 464 1.7E-17 T 29-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 GBCGDNIH2_RS11815 dad87ed83a33701945933c96964ec63d 495 SUPERFAMILY SSF56784 25 183 4.27E-12 T 29-03-2018 IPR023214 HAD-like domain GBCGDNIH2_RS02890 d29ecde3dfa179d08940cd7845e3e63e 106 ProSitePatterns PS01108 Ribosomal protein L24 signature. 8 25 - T 29-03-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS02890 d29ecde3dfa179d08940cd7845e3e63e 106 SMART SM00739 4 31 4.6E-6 T 29-03-2018 IPR005824 KOW GBCGDNIH2_RS02890 d29ecde3dfa179d08940cd7845e3e63e 106 Gene3D G3DSA:2.30.30.30 2 93 8.1E-36 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 GBCGDNIH2_RS02890 d29ecde3dfa179d08940cd7845e3e63e 106 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 3 98 21.69 T 29-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS02890 d29ecde3dfa179d08940cd7845e3e63e 106 Pfam PF00467 KOW motif 7 37 1.3E-6 T 29-03-2018 IPR005824 KOW GBCGDNIH2_RS02890 d29ecde3dfa179d08940cd7845e3e63e 106 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 3 104 3.4E-37 T 29-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS02890 d29ecde3dfa179d08940cd7845e3e63e 106 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 40 104 4.0E-24 T 29-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS02890 d29ecde3dfa179d08940cd7845e3e63e 106 SUPERFAMILY SSF50104 2 100 1.73E-34 T 29-03-2018 IPR008991 Translation protein SH3-like domain GBCGDNIH2_RS12400 5c7e804b9f7473b565cb4df0c1d66a47 138 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 21 128 4.8E-19 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 GBCGDNIH2_RS12400 5c7e804b9f7473b565cb4df0c1d66a47 138 Gene3D G3DSA:3.30.300.20 20 134 4.7E-28 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta GBCGDNIH2_RS12400 5c7e804b9f7473b565cb4df0c1d66a47 138 ProSitePatterns PS01319 Ribosome-binding factor A signature. 93 114 - T 29-03-2018 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 GBCGDNIH2_RS12400 5c7e804b9f7473b565cb4df0c1d66a47 138 SUPERFAMILY SSF89919 19 129 4.84E-29 T 29-03-2018 IPR023799 Ribosome-binding factor A domain GBCGDNIH2_RS12400 5c7e804b9f7473b565cb4df0c1d66a47 138 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 25 111 2.0E-24 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 GBCGDNIH2_RS12400 5c7e804b9f7473b565cb4df0c1d66a47 138 Pfam PF02033 Ribosome-binding factor A 22 127 5.0E-27 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 GBCGDNIH2_RS12400 5c7e804b9f7473b565cb4df0c1d66a47 138 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 18 134 20.21 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 GBCGDNIH2_RS01625 5f7cfc998d252e40c0999a1377656bff 141 Pfam PF01479 S4 domain 26 73 7.9E-11 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 GBCGDNIH2_RS01625 5f7cfc998d252e40c0999a1377656bff 141 Gene3D G3DSA:3.10.290.10 20 121 5.9E-20 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 GBCGDNIH2_RS01625 5f7cfc998d252e40c0999a1377656bff 141 SMART SM00363 26 90 2.8E-7 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 GBCGDNIH2_RS01625 5f7cfc998d252e40c0999a1377656bff 141 SUPERFAMILY SSF55174 26 114 1.28E-19 T 29-03-2018 GBCGDNIH2_RS08155 a989e15b373d49ba767df40b9b4ebdd3 611 SUPERFAMILY SSF51294 267 403 3.77E-13 T 29-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 GBCGDNIH2_RS08155 a989e15b373d49ba767df40b9b4ebdd3 611 Gene3D G3DSA:2.170.16.10 264 473 2.7E-20 T 29-03-2018 GBCGDNIH2_RS08155 a989e15b373d49ba767df40b9b4ebdd3 611 Pfam PF13403 Hint domain 266 405 1.2E-42 T 29-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 GBCGDNIH2_RS08155 a989e15b373d49ba767df40b9b4ebdd3 611 SMART SM00306 265 374 0.0097 T 29-03-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 GBCGDNIH2_RS04125 c86ef4971e4f00d86e4b2803a5a63c73 537 SUPERFAMILY SSF52096 146 203 2.15E-50 T 29-03-2018 IPR029045 ClpP/crotonase-like domain GBCGDNIH2_RS04125 c86ef4971e4f00d86e4b2803a5a63c73 537 SUPERFAMILY SSF52096 277 453 2.15E-50 T 29-03-2018 IPR029045 ClpP/crotonase-like domain GBCGDNIH2_RS04125 c86ef4971e4f00d86e4b2803a5a63c73 537 SMART SM00245 259 453 1.2E-32 T 29-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 GBCGDNIH2_RS04125 c86ef4971e4f00d86e4b2803a5a63c73 537 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 184 252 5.5E-8 T 29-03-2018 IPR001478 PDZ domain GO:0005515 GBCGDNIH2_RS04125 c86ef4971e4f00d86e4b2803a5a63c73 537 Pfam PF03572 Peptidase family S41 285 450 3.5E-36 T 29-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 GBCGDNIH2_RS04125 c86ef4971e4f00d86e4b2803a5a63c73 537 SUPERFAMILY SSF50156 179 257 5.12E-12 T 29-03-2018 IPR001478 PDZ domain GO:0005515 GBCGDNIH2_RS04125 c86ef4971e4f00d86e4b2803a5a63c73 537 Gene3D G3DSA:2.30.42.10 175 267 1.4E-12 T 29-03-2018 GBCGDNIH2_RS04125 c86ef4971e4f00d86e4b2803a5a63c73 537 Gene3D G3DSA:3.90.226.10 268 479 2.4E-45 T 29-03-2018 GBCGDNIH2_RS04125 c86ef4971e4f00d86e4b2803a5a63c73 537 SMART SM00228 185 256 3.4E-8 T 29-03-2018 IPR001478 PDZ domain GO:0005515 GBCGDNIH2_RS06670 678bb349398af02180f9d1eaf4935f4c 217 Pfam PF13419 Haloacid dehalogenase-like hydrolase 4 182 3.1E-27 T 29-03-2018 IPR023214 HAD-like domain GBCGDNIH2_RS06670 678bb349398af02180f9d1eaf4935f4c 217 Gene3D G3DSA:1.10.150.240 17 72 7.3E-14 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 GBCGDNIH2_RS06670 678bb349398af02180f9d1eaf4935f4c 217 Gene3D G3DSA:3.40.50.1000 73 216 4.8E-30 T 29-03-2018 IPR023214 HAD-like domain GBCGDNIH2_RS06670 678bb349398af02180f9d1eaf4935f4c 217 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 96 109 3.4E-5 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 GBCGDNIH2_RS06670 678bb349398af02180f9d1eaf4935f4c 217 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 127 143 3.4E-5 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 GBCGDNIH2_RS06670 678bb349398af02180f9d1eaf4935f4c 217 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 1 12 3.4E-5 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 GBCGDNIH2_RS06670 678bb349398af02180f9d1eaf4935f4c 217 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 58 182 3.0E-8 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 GBCGDNIH2_RS06670 678bb349398af02180f9d1eaf4935f4c 217 SUPERFAMILY SSF56784 1 213 6.79E-50 T 29-03-2018 IPR023214 HAD-like domain GBCGDNIH2_RS08480 1bf1aa0c86adb3c29496172e247a2c8d 1021 SUPERFAMILY SSF51120 822 1013 6.67E-10 T 29-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal GBCGDNIH2_RS08480 1bf1aa0c86adb3c29496172e247a2c8d 1021 Pfam PF16168 Adhesin of bacterial autotransporter system, probable stalk 49 99 8.9E-7 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08480 1bf1aa0c86adb3c29496172e247a2c8d 1021 Pfam PF16168 Adhesin of bacterial autotransporter system, probable stalk 105 156 2.9E-7 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08480 1bf1aa0c86adb3c29496172e247a2c8d 1021 SUPERFAMILY SSF51120 644 753 2.01E-10 T 29-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal GBCGDNIH2_RS08480 1bf1aa0c86adb3c29496172e247a2c8d 1021 SUPERFAMILY SSF51120 565 604 2.01E-10 T 29-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal GBCGDNIH2_RS08480 1bf1aa0c86adb3c29496172e247a2c8d 1021 Gene3D G3DSA:2.150.10.10 839 1019 5.9E-8 T 29-03-2018 GBCGDNIH2_RS08480 1bf1aa0c86adb3c29496172e247a2c8d 1021 Gene3D G3DSA:2.150.10.10 544 746 1.3E-7 T 29-03-2018 GBCGDNIH2_RS08480 1bf1aa0c86adb3c29496172e247a2c8d 1021 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 52 88 1.0E-8 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08480 1bf1aa0c86adb3c29496172e247a2c8d 1021 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 405 439 2.8E-8 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08480 1bf1aa0c86adb3c29496172e247a2c8d 1021 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 32 69 1.3E-5 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08480 1bf1aa0c86adb3c29496172e247a2c8d 1021 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 91 126 1.1E-9 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08480 1bf1aa0c86adb3c29496172e247a2c8d 1021 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 127 164 5.4E-8 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08480 1bf1aa0c86adb3c29496172e247a2c8d 1021 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 295 328 1.6E-9 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08480 1bf1aa0c86adb3c29496172e247a2c8d 1021 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 330 366 1.2E-9 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08480 1bf1aa0c86adb3c29496172e247a2c8d 1021 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 276 309 2.0E-6 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08480 1bf1aa0c86adb3c29496172e247a2c8d 1021 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 368 404 9.6E-8 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08480 1bf1aa0c86adb3c29496172e247a2c8d 1021 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 169 200 8.0E-5 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS00700 ff12536b31c1f46b11eb9f79fa90e4df 342 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 6 331 1.5E-98 T 29-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 GBCGDNIH2_RS00700 ff12536b31c1f46b11eb9f79fa90e4df 342 PIRSF PIRSF000267 1 342 7.3E-112 T 29-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 GBCGDNIH2_RS00700 ff12536b31c1f46b11eb9f79fa90e4df 342 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 4 222 1.4E-52 T 29-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 GBCGDNIH2_RS01990 98ef879cad230ab2d355369e489f1c0d 302 Gene3D G3DSA:1.10.10.10 1 82 6.6E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS01990 98ef879cad230ab2d355369e489f1c0d 302 SUPERFAMILY SSF53850 92 289 4.56E-31 T 29-03-2018 GBCGDNIH2_RS01990 98ef879cad230ab2d355369e489f1c0d 302 Gene3D G3DSA:3.40.190.10 182 259 9.4E-8 T 29-03-2018 GBCGDNIH2_RS01990 98ef879cad230ab2d355369e489f1c0d 302 Pfam PF03466 LysR substrate binding domain 91 287 3.4E-25 T 29-03-2018 IPR005119 LysR, substrate-binding GBCGDNIH2_RS01990 98ef879cad230ab2d355369e489f1c0d 302 Gene3D G3DSA:3.40.190.10 90 181 1.4E-15 T 29-03-2018 GBCGDNIH2_RS01990 98ef879cad230ab2d355369e489f1c0d 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 6.8E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS01990 98ef879cad230ab2d355369e489f1c0d 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 6.8E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS01990 98ef879cad230ab2d355369e489f1c0d 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 6.8E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS01990 98ef879cad230ab2d355369e489f1c0d 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 3.6E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS01990 98ef879cad230ab2d355369e489f1c0d 302 SUPERFAMILY SSF46785 4 88 1.2E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS04765 88e24b0a4298057b86415375e3299496 206 Pfam PF11363 Protein of unknown function (DUF3164) 9 204 1.6E-65 T 29-03-2018 IPR021505 Bacteriophage B3, Orf6 GBCGDNIH2_RS11165 3383da0f3f18287c893544c51567495b 418 PRINTS PR00758 Arsenical pump membrane protein signature 178 201 7.7E-22 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 GBCGDNIH2_RS11165 3383da0f3f18287c893544c51567495b 418 PRINTS PR00758 Arsenical pump membrane protein signature 390 414 7.7E-22 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 GBCGDNIH2_RS11165 3383da0f3f18287c893544c51567495b 418 PRINTS PR00758 Arsenical pump membrane protein signature 275 299 7.7E-22 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 GBCGDNIH2_RS11165 3383da0f3f18287c893544c51567495b 418 PRINTS PR00758 Arsenical pump membrane protein signature 357 382 7.7E-22 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 GBCGDNIH2_RS11165 3383da0f3f18287c893544c51567495b 418 PRINTS PR00758 Arsenical pump membrane protein signature 105 129 7.7E-22 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 GBCGDNIH2_RS11165 3383da0f3f18287c893544c51567495b 418 Pfam PF03600 Citrate transporter 23 350 4.4E-30 T 29-03-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 GBCGDNIH2_RS00340 6e922c8582d9b23be4c65cfd2503480b 141 Gene3D G3DSA:3.30.300.20 47 141 1.8E-21 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta GBCGDNIH2_RS00340 6e922c8582d9b23be4c65cfd2503480b 141 SUPERFAMILY SSF82784 1 138 4.84E-41 T 29-03-2018 IPR003718 OsmC/Ohr family GBCGDNIH2_RS00340 6e922c8582d9b23be4c65cfd2503480b 141 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 7 139 1.8E-54 T 29-03-2018 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 GBCGDNIH2_RS00340 6e922c8582d9b23be4c65cfd2503480b 141 Gene3D G3DSA:2.20.25.10 2 46 3.7E-16 T 29-03-2018 GBCGDNIH2_RS00340 6e922c8582d9b23be4c65cfd2503480b 141 Pfam PF02566 OsmC-like protein 42 136 2.8E-15 T 29-03-2018 IPR003718 OsmC/Ohr family GBCGDNIH2_RS01210 284a585ab932e53e2993a239a768c7fb 399 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 243 252 - T 29-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 GBCGDNIH2_RS01210 284a585ab932e53e2993a239a768c7fb 399 Gene3D G3DSA:3.40.640.10 61 281 8.2E-47 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GBCGDNIH2_RS01210 284a585ab932e53e2993a239a768c7fb 399 SUPERFAMILY SSF53383 12 392 2.18E-100 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase GBCGDNIH2_RS01210 284a585ab932e53e2993a239a768c7fb 399 Pfam PF00155 Aminotransferase class I and II 48 387 7.4E-53 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 GBCGDNIH2_RS01210 284a585ab932e53e2993a239a768c7fb 399 Gene3D G3DSA:3.90.1150.10 282 397 1.0E-22 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 GBCGDNIH2_RS07585 47298f080ff50968264b3caeabe412e9 228 SUPERFAMILY SSF52540 28 181 2.33E-12 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS07585 47298f080ff50968264b3caeabe412e9 228 Gene3D G3DSA:3.40.50.300 24 194 2.1E-9 T 29-03-2018 GBCGDNIH2_RS05295 7ac228ff63755f1a562bfb0e1f57afa6 158 Pfam PF02021 Uncharacterised protein family UPF0102 48 137 5.9E-20 T 29-03-2018 IPR003509 Uncharacterised protein family UPF0102 GBCGDNIH2_RS05295 7ac228ff63755f1a562bfb0e1f57afa6 158 SUPERFAMILY SSF52980 43 150 1.72E-18 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 GBCGDNIH2_RS05295 7ac228ff63755f1a562bfb0e1f57afa6 158 Hamap MF_00048 UPF0102 protein YraN [yraN]. 41 150 18.565 T 29-03-2018 IPR003509 Uncharacterised protein family UPF0102 GBCGDNIH2_RS05295 7ac228ff63755f1a562bfb0e1f57afa6 158 Gene3D G3DSA:3.40.1350.10 47 156 8.4E-28 T 29-03-2018 GBCGDNIH2_RS05745 39aab2e2a847809dc5c70da561ac46c3 444 Pfam PF04610 TrbL/VirB6 plasmid conjugal transfer protein 37 254 8.6E-57 T 29-03-2018 IPR007688 Plasmid conjugal transfer TrbL/VirB6 GO:0030255 GBCGDNIH2_RS05745 39aab2e2a847809dc5c70da561ac46c3 444 TIGRFAM TIGR02783 TrbL_P: P-type conjugative transfer protein TrbL 1 307 4.6E-69 T 29-03-2018 IPR014150 Conjugal transfer, TrbL GBCGDNIH2_RS02660 d4182b2ad42d53a69f20f7b7450f70cc 842 Pfam PF04168 A predicted alpha-helical domain with a conserved ER motif. 508 821 8.6E-57 T 29-03-2018 IPR007296 Domain of unknown function DUF403 GBCGDNIH2_RS02660 d4182b2ad42d53a69f20f7b7450f70cc 842 Pfam PF14403 Circularly permuted ATP-grasp type 2 71 457 8.6E-120 T 29-03-2018 IPR025841 Circularly permuted ATP-grasp type 2 GBCGDNIH2_RS02660 d4182b2ad42d53a69f20f7b7450f70cc 842 SUPERFAMILY SSF56059 60 218 1.2E-8 T 29-03-2018 GBCGDNIH2_RS02070 8dde732403060a0cae91bc864299362b 318 SUPERFAMILY SSF53613 6 315 7.33E-77 T 29-03-2018 IPR029056 Ribokinase-like GBCGDNIH2_RS02070 8dde732403060a0cae91bc864299362b 318 Pfam PF00294 pfkB family carbohydrate kinase 52 314 2.7E-51 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB GBCGDNIH2_RS02070 8dde732403060a0cae91bc864299362b 318 Gene3D G3DSA:3.40.1190.20 4 317 1.4E-63 T 29-03-2018 IPR029056 Ribokinase-like GBCGDNIH2_RS02070 8dde732403060a0cae91bc864299362b 318 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 271 284 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 GBCGDNIH2_RS04310 8ba0a4d2dacea50c14b1298700b3c441 398 Gene3D G3DSA:3.90.1150.10 265 385 7.5E-19 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 GBCGDNIH2_RS04310 8ba0a4d2dacea50c14b1298700b3c441 398 SUPERFAMILY SSF53383 11 386 7.73E-60 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase GBCGDNIH2_RS04310 8ba0a4d2dacea50c14b1298700b3c441 398 Gene3D G3DSA:3.40.640.10 29 264 3.1E-16 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GBCGDNIH2_RS04310 8ba0a4d2dacea50c14b1298700b3c441 398 PIRSF PIRSF000525 1 390 2.6E-36 T 29-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 GBCGDNIH2_RS04310 8ba0a4d2dacea50c14b1298700b3c441 398 TIGRFAM TIGR01365 serC_2: phosphoserine aminotransferase 10 388 2.3E-163 T 29-03-2018 IPR006271 Phosphoserine aminotransferase, Methanosarcina-type GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52 GBCGDNIH2_RS07295 7653ae420e7b3a2d9dc07753de622257 60 Pfam PF04325 Protein of unknown function (DUF465) 8 52 8.2E-12 T 29-03-2018 IPR007420 Protein of unknown function DUF465 GBCGDNIH2_RS07295 7653ae420e7b3a2d9dc07753de622257 60 Gene3D G3DSA:1.20.5.730 1 58 0.0012 T 29-03-2018 GBCGDNIH2_RS05530 eca85f07da4f77ffd5684dea16efedae 84 Gene3D G3DSA:1.10.1470.10 1 62 1.3E-12 T 29-03-2018 IPR008462 CsbD-like domain GBCGDNIH2_RS05530 eca85f07da4f77ffd5684dea16efedae 84 Pfam PF05532 CsbD-like 6 56 1.1E-16 T 29-03-2018 IPR008462 CsbD-like domain GBCGDNIH2_RS05530 eca85f07da4f77ffd5684dea16efedae 84 SUPERFAMILY SSF69047 5 62 4.32E-12 T 29-03-2018 IPR008462 CsbD-like domain GBCGDNIH2_RS04205 eda1a46b0dc75fdc337ce867633abce2 305 Pfam PF00218 Indole-3-glycerol phosphate synthase 37 292 4.2E-94 T 29-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 GBCGDNIH2_RS04205 eda1a46b0dc75fdc337ce867633abce2 305 SUPERFAMILY SSF51366 44 294 4.47E-92 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 GBCGDNIH2_RS04205 eda1a46b0dc75fdc337ce867633abce2 305 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 88 106 - T 29-03-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 GBCGDNIH2_RS04205 eda1a46b0dc75fdc337ce867633abce2 305 Gene3D G3DSA:3.20.20.70 43 295 8.9E-74 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS04205 eda1a46b0dc75fdc337ce867633abce2 305 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 35 294 36.29 T 29-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 GBCGDNIH2_RS09920 bd03e1282467818760a8561ec1443a3c 365 Pfam PF00005 ABC transporter 19 164 5.6E-36 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GBCGDNIH2_RS09920 bd03e1282467818760a8561ec1443a3c 365 Gene3D G3DSA:3.40.50.300 1 265 6.7E-71 T 29-03-2018 GBCGDNIH2_RS09920 bd03e1282467818760a8561ec1443a3c 365 SUPERFAMILY SSF52540 3 240 1.98E-80 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS09920 bd03e1282467818760a8561ec1443a3c 365 SMART SM00382 27 214 5.1E-21 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS09920 bd03e1282467818760a8561ec1443a3c 365 SUPERFAMILY SSF50331 251 320 3.12E-5 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal GBCGDNIH2_RS09920 bd03e1282467818760a8561ec1443a3c 365 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GBCGDNIH2_RS02005 5ca7da8a3768b76ab4e9e2574ac7127c 170 Gene3D G3DSA:3.40.630.30 6 167 8.5E-30 T 29-03-2018 GBCGDNIH2_RS02005 5ca7da8a3768b76ab4e9e2574ac7127c 170 Pfam PF00583 Acetyltransferase (GNAT) family 32 134 1.2E-16 T 29-03-2018 IPR000182 GNAT domain GO:0008080 GBCGDNIH2_RS02005 5ca7da8a3768b76ab4e9e2574ac7127c 170 SUPERFAMILY SSF55729 16 148 8.97E-29 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase GBCGDNIH2_RS02005 5ca7da8a3768b76ab4e9e2574ac7127c 170 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 26 152 1.8E-26 T 29-03-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 GBCGDNIH2_RS02320 161aeb27d1aa57d0681dabc10246accd 150 Gene3D G3DSA:2.60.120.10 4 147 1.1E-51 T 29-03-2018 IPR014710 RmlC-like jelly roll fold GBCGDNIH2_RS02320 161aeb27d1aa57d0681dabc10246accd 150 Pfam PF06172 Cupin superfamily (DUF985) 16 142 3.7E-46 T 29-03-2018 IPR009327 Cupin domain of unknown function DUF985 GBCGDNIH2_RS02320 161aeb27d1aa57d0681dabc10246accd 150 SUPERFAMILY SSF51182 9 148 3.68E-52 T 29-03-2018 IPR011051 RmlC-like cupin domain GBCGDNIH2_RS10390 45e8ac78620e3c7b6b699d43c6fa3f80 361 Gene3D G3DSA:1.10.3720.10 7 356 1.3E-34 T 29-03-2018 GBCGDNIH2_RS10390 45e8ac78620e3c7b6b699d43c6fa3f80 361 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 148 355 9.7E-33 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GBCGDNIH2_RS10390 45e8ac78620e3c7b6b699d43c6fa3f80 361 SUPERFAMILY SSF161098 125 340 1.21E-15 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GBCGDNIH2_RS10330 b4292082f9ee0afea851f2bd7aca02e0 397 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 91 381 3.7E-25 T 29-03-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD GBCGDNIH2_RS10330 b4292082f9ee0afea851f2bd7aca02e0 397 TIGRFAM TIGR03476 HpnL: putative membrane protein 84 391 2.3E-75 T 29-03-2018 GBCGDNIH2_RS07865 106c11985b8c46e691b18bbf6f931129 199 SUPERFAMILY SSF55021 118 197 2.29E-25 T 29-03-2018 GBCGDNIH2_RS07865 106c11985b8c46e691b18bbf6f931129 199 Gene3D G3DSA:3.30.70.1150 126 198 1.2E-26 T 29-03-2018 GBCGDNIH2_RS07865 106c11985b8c46e691b18bbf6f931129 199 Pfam PF10369 Small subunit of acetolactate synthase 122 195 2.4E-26 T 29-03-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 GBCGDNIH2_RS07865 106c11985b8c46e691b18bbf6f931129 199 SUPERFAMILY SSF55021 36 113 5.19E-15 T 29-03-2018 GBCGDNIH2_RS07865 106c11985b8c46e691b18bbf6f931129 199 Gene3D G3DSA:3.30.70.260 25 125 2.8E-18 T 29-03-2018 GBCGDNIH2_RS07865 106c11985b8c46e691b18bbf6f931129 199 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 34 113 2.0E-22 T 29-03-2018 GBCGDNIH2_RS07865 106c11985b8c46e691b18bbf6f931129 199 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 36 195 2.4E-49 T 29-03-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 GBCGDNIH2_RS07865 106c11985b8c46e691b18bbf6f931129 199 Pfam PF01842 ACT domain 36 104 4.2E-9 T 29-03-2018 IPR002912 ACT domain GBCGDNIH2_RS00315 fee4209fcb2f7da8ea29b145962015ed 171 Pfam PF03737 Aldolase/RraA 15 163 4.2E-39 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein GBCGDNIH2_RS00315 fee4209fcb2f7da8ea29b145962015ed 171 Gene3D G3DSA:3.50.30.40 8 169 1.2E-39 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein GBCGDNIH2_RS00315 fee4209fcb2f7da8ea29b145962015ed 171 TIGRFAM TIGR01935 NOT-MenG: RraA family 15 164 2.2E-53 T 29-03-2018 IPR010203 Regulator of ribonuclease activity A GO:0008428|GO:0051252 GBCGDNIH2_RS00315 fee4209fcb2f7da8ea29b145962015ed 171 SUPERFAMILY SSF89562 13 165 3.27E-41 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein GBCGDNIH2_RS12455 7b6746eb4c5e5bad00a4b14b85434c13 394 Pfam PF13506 Glycosyl transferase family 21 99 273 2.6E-47 T 29-03-2018 IPR025993 Ceramide glucosyltransferase GO:0016757 KEGG: 00600+2.4.1.80|MetaCyc: PWY-5129|MetaCyc: PWY-7836|MetaCyc: PWY-7838|MetaCyc: PWY-7839|MetaCyc: PWY-7841|Reactome: R-HSA-1660662 GBCGDNIH2_RS12455 7b6746eb4c5e5bad00a4b14b85434c13 394 SUPERFAMILY SSF53448 43 287 1.59E-33 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS12455 7b6746eb4c5e5bad00a4b14b85434c13 394 TIGRFAM TIGR03472 HpnI: hopanoid biosynthesis associated glycosyl transferase protein HpnI 8 373 5.7E-130 T 29-03-2018 IPR017835 Hopanoid biosynthesis associated glycosyltransferase, HpnI GBCGDNIH2_RS12455 7b6746eb4c5e5bad00a4b14b85434c13 394 Gene3D G3DSA:3.90.550.10 27 279 2.0E-29 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS00925 9cf1974a9da34171528305e2101222b2 204 Pfam PF02669 K+-transporting ATPase, c chain 6 201 2.1E-69 T 29-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 GBCGDNIH2_RS00925 9cf1974a9da34171528305e2101222b2 204 TIGRFAM TIGR00681 kdpC: K+-transporting ATPase, C subunit 3 202 3.1E-61 T 29-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 GBCGDNIH2_RS00925 9cf1974a9da34171528305e2101222b2 204 Hamap MF_00276 Potassium-transporting ATPase KdpC subunit [kdpC]. 2 203 34.484 T 29-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 GBCGDNIH2_RS00925 9cf1974a9da34171528305e2101222b2 204 PIRSF PIRSF001296 1 204 1.6E-70 T 29-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 GBCGDNIH2_RS02470 d9f48ee6da71b791d129da364a3ed84c 621 ProSitePatterns PS00211 ABC transporters family signature. 516 530 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GBCGDNIH2_RS02470 d9f48ee6da71b791d129da364a3ed84c 621 Gene3D G3DSA:3.40.50.300 364 619 1.2E-75 T 29-03-2018 GBCGDNIH2_RS02470 d9f48ee6da71b791d129da364a3ed84c 621 Pfam PF00005 ABC transporter 395 544 1.5E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GBCGDNIH2_RS02470 d9f48ee6da71b791d129da364a3ed84c 621 SUPERFAMILY SSF90123 52 343 1.05E-37 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 GBCGDNIH2_RS02470 d9f48ee6da71b791d129da364a3ed84c 621 SUPERFAMILY SSF90123 520 528 1.05E-37 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 GBCGDNIH2_RS02470 d9f48ee6da71b791d129da364a3ed84c 621 SMART SM00382 404 590 1.3E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS02470 d9f48ee6da71b791d129da364a3ed84c 621 SUPERFAMILY SSF52540 369 614 7.88E-87 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS02470 d9f48ee6da71b791d129da364a3ed84c 621 Pfam PF00664 ABC transporter transmembrane region 67 325 9.3E-15 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 GBCGDNIH2_RS02470 d9f48ee6da71b791d129da364a3ed84c 621 Gene3D G3DSA:1.20.1560.10 34 363 2.8E-29 T 29-03-2018 GBCGDNIH2_RS03055 688fa9f4dd4359bdd8aaf7c7fca94f75 86 PRINTS PR00160 Glutaredoxin signature 47 60 4.8E-16 T 29-03-2018 IPR014025 Glutaredoxin subgroup GBCGDNIH2_RS03055 688fa9f4dd4359bdd8aaf7c7fca94f75 86 PRINTS PR00160 Glutaredoxin signature 4 22 4.8E-16 T 29-03-2018 IPR014025 Glutaredoxin subgroup GBCGDNIH2_RS03055 688fa9f4dd4359bdd8aaf7c7fca94f75 86 PRINTS PR00160 Glutaredoxin signature 61 74 4.8E-16 T 29-03-2018 IPR014025 Glutaredoxin subgroup GBCGDNIH2_RS03055 688fa9f4dd4359bdd8aaf7c7fca94f75 86 Pfam PF00462 Glutaredoxin 4 64 1.1E-18 T 29-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 GBCGDNIH2_RS03055 688fa9f4dd4359bdd8aaf7c7fca94f75 86 TIGRFAM TIGR02181 GRX_bact: glutaredoxin 3 4 83 3.9E-31 T 29-03-2018 IPR011900 Glutaredoxin, GrxC GO:0045454 GBCGDNIH2_RS03055 688fa9f4dd4359bdd8aaf7c7fca94f75 86 SUPERFAMILY SSF52833 4 84 5.06E-26 T 29-03-2018 IPR012336 Thioredoxin-like fold GBCGDNIH2_RS03055 688fa9f4dd4359bdd8aaf7c7fca94f75 86 ProSitePatterns PS00195 Glutaredoxin active site. 6 22 - T 29-03-2018 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 GBCGDNIH2_RS03055 688fa9f4dd4359bdd8aaf7c7fca94f75 86 Gene3D G3DSA:3.40.30.10 2 85 4.5E-26 T 29-03-2018 GBCGDNIH2_RS07815 e71c3d1e9c6c8e02c6217d8ba0cb94f9 617 Pfam PF00905 Penicillin binding protein transpeptidase domain 261 596 5.6E-70 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 GBCGDNIH2_RS07815 e71c3d1e9c6c8e02c6217d8ba0cb94f9 617 SUPERFAMILY SSF56519 51 242 1.03E-39 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 GBCGDNIH2_RS07815 e71c3d1e9c6c8e02c6217d8ba0cb94f9 617 TIGRFAM TIGR03423 pbp2_mrdA: penicillin-binding protein 2 13 600 3.4E-202 T 29-03-2018 IPR017790 Penicillin-binding protein 2 GO:0008658|GO:0016020 GBCGDNIH2_RS07815 e71c3d1e9c6c8e02c6217d8ba0cb94f9 617 Pfam PF03717 Penicillin-binding Protein dimerisation domain 58 228 8.1E-33 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 GBCGDNIH2_RS07815 e71c3d1e9c6c8e02c6217d8ba0cb94f9 617 Gene3D G3DSA:3.40.710.10 239 606 1.8E-86 T 29-03-2018 GBCGDNIH2_RS07815 e71c3d1e9c6c8e02c6217d8ba0cb94f9 617 Gene3D G3DSA:3.90.1310.10 27 238 4.9E-40 T 29-03-2018 GBCGDNIH2_RS07815 e71c3d1e9c6c8e02c6217d8ba0cb94f9 617 SUPERFAMILY SSF56601 243 601 1.44E-94 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like GBCGDNIH2_RS10110 4ff3869919ae26ccf69ec12c9de488c2 552 Gene3D G3DSA:1.20.1250.20 270 497 1.5E-21 T 29-03-2018 GBCGDNIH2_RS10110 4ff3869919ae26ccf69ec12c9de488c2 552 SUPERFAMILY SSF103473 24 487 1.03E-43 T 29-03-2018 IPR020846 Major facilitator superfamily domain GBCGDNIH2_RS10110 4ff3869919ae26ccf69ec12c9de488c2 552 Pfam PF07690 Major Facilitator Superfamily 41 443 3.2E-32 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 GBCGDNIH2_RS10110 4ff3869919ae26ccf69ec12c9de488c2 552 Gene3D G3DSA:1.20.1250.20 29 252 3.1E-19 T 29-03-2018 GBCGDNIH2_RS08820 694165933bed3aca8a53138aae699f40 133 Pfam PF12200 Domain of unknown function (DUF3597) 3 132 6.0E-39 T 29-03-2018 IPR022016 Domain of unknown function DUF3597 GBCGDNIH2_RS08820 694165933bed3aca8a53138aae699f40 133 SUPERFAMILY SSF158634 1 133 1.19E-38 T 29-03-2018 GBCGDNIH2_RS05850 7901d28cd36bf76cff60fb7cd3910f64 350 Gene3D G3DSA:3.30.1330.60 215 350 1.1E-27 T 29-03-2018 IPR006665 OmpA-like domain GBCGDNIH2_RS05850 7901d28cd36bf76cff60fb7cd3910f64 350 Gene3D G3DSA:1.20.5.730 130 214 7.4E-4 T 29-03-2018 GBCGDNIH2_RS05850 7901d28cd36bf76cff60fb7cd3910f64 350 SUPERFAMILY SSF103088 224 347 6.28E-26 T 29-03-2018 IPR006665 OmpA-like domain GBCGDNIH2_RS05850 7901d28cd36bf76cff60fb7cd3910f64 350 Pfam PF00691 OmpA family 235 341 1.5E-17 T 29-03-2018 IPR006665 OmpA-like domain GBCGDNIH2_RS05850 7901d28cd36bf76cff60fb7cd3910f64 350 Gene3D G3DSA:1.20.5.170 44 129 0.0013 T 29-03-2018 GBCGDNIH2_RS03560 284203d4a735b1387605e427e41cfeb2 329 Pfam PF03968 OstA-like protein 163 291 1.2E-7 T 29-03-2018 IPR005653 Organic solvent tolerance-like, N-terminal GBCGDNIH2_RS03560 284203d4a735b1387605e427e41cfeb2 329 Pfam PF03968 OstA-like protein 48 161 3.5E-9 T 29-03-2018 IPR005653 Organic solvent tolerance-like, N-terminal GBCGDNIH2_RS03560 284203d4a735b1387605e427e41cfeb2 329 Gene3D G3DSA:2.60.450.10 163 307 2.4E-20 T 29-03-2018 GBCGDNIH2_RS03560 284203d4a735b1387605e427e41cfeb2 329 Gene3D G3DSA:2.60.450.10 32 162 5.2E-22 T 29-03-2018 GBCGDNIH2_RS00190 38eb3c1a9fa391e4b95b8c38064526e2 295 Gene3D G3DSA:3.20.20.370 19 267 1.1E-29 T 29-03-2018 GBCGDNIH2_RS00190 38eb3c1a9fa391e4b95b8c38064526e2 295 Pfam PF01522 Polysaccharide deacetylase 44 134 2.8E-16 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 GBCGDNIH2_RS00190 38eb3c1a9fa391e4b95b8c38064526e2 295 Pfam PF11959 Domain of unknown function (DUF3473) 154 272 4.0E-23 T 29-03-2018 IPR022560 Domain of unknown function DUF3473 GBCGDNIH2_RS00190 38eb3c1a9fa391e4b95b8c38064526e2 295 SUPERFAMILY SSF88713 44 238 4.45E-30 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 GBCGDNIH2_RS02370 dd1dc9a42154a3b62c4029188d2ee94c 116 TIGRFAM TIGR02222 chap_CsaA: export-related chaperone protein CsaA 11 115 1.4E-39 T 29-03-2018 IPR008231 Probable chaperone CsaA GBCGDNIH2_RS02370 dd1dc9a42154a3b62c4029188d2ee94c 116 SUPERFAMILY SSF50249 8 115 2.23E-28 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold GBCGDNIH2_RS02370 dd1dc9a42154a3b62c4029188d2ee94c 116 Pfam PF01588 Putative tRNA binding domain 19 113 6.5E-14 T 29-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 GBCGDNIH2_RS02370 dd1dc9a42154a3b62c4029188d2ee94c 116 Gene3D G3DSA:2.40.50.140 7 116 6.0E-19 T 29-03-2018 GBCGDNIH2_RS10830 0c5611c524684787e3ef3d78db4dcab6 143 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 20 134 4.4E-32 T 29-03-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 GBCGDNIH2_RS10830 0c5611c524684787e3ef3d78db4dcab6 143 ProSitePatterns PS01000 Succinate dehydrogenase cytochrome b subunit signature 1. 21 45 - T 29-03-2018 IPR018495 Succinate dehydrogenase, cytochrome b subunit, conserved site GO:0000104|GO:0006099|GO:0009055|GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 GBCGDNIH2_RS10830 0c5611c524684787e3ef3d78db4dcab6 143 SUPERFAMILY SSF81343 19 137 4.8E-36 T 29-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 GBCGDNIH2_RS10830 0c5611c524684787e3ef3d78db4dcab6 143 PIRSF PIRSF000178 7 140 3.9E-42 T 29-03-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 GBCGDNIH2_RS10830 0c5611c524684787e3ef3d78db4dcab6 143 Gene3D G3DSA:1.20.1300.10 17 139 1.3E-27 T 29-03-2018 GBCGDNIH2_RS10830 0c5611c524684787e3ef3d78db4dcab6 143 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 20 137 3.3E-41 T 29-03-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 GBCGDNIH2_RS10830 0c5611c524684787e3ef3d78db4dcab6 143 ProSitePatterns PS01001 Succinate dehydrogenase cytochrome b subunit signature 2. 96 109 - T 29-03-2018 IPR018495 Succinate dehydrogenase, cytochrome b subunit, conserved site GO:0000104|GO:0006099|GO:0009055|GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 GBCGDNIH2_RS08860 9a1c35e5d0a1b3248c1a575f887fa649 114 SUPERFAMILY SSF54565 3 91 1.06E-29 T 29-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS08860 9a1c35e5d0a1b3248c1a575f887fa649 114 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 82 5.1E-29 T 29-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS08860 9a1c35e5d0a1b3248c1a575f887fa649 114 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 80 23.319 T 29-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS08860 9a1c35e5d0a1b3248c1a575f887fa649 114 Pfam PF00886 Ribosomal protein S16 9 69 1.2E-23 T 29-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS08860 9a1c35e5d0a1b3248c1a575f887fa649 114 Gene3D G3DSA:3.30.1320.10 3 88 5.1E-30 T 29-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS08860 9a1c35e5d0a1b3248c1a575f887fa649 114 ProSitePatterns PS00732 Ribosomal protein S16 signature. 3 12 - T 29-03-2018 IPR020592 Ribosomal protein S16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS09215 b8bd7d1e9beda009de32fc34da775fdd 155 SUPERFAMILY SSF54523 15 129 4.71E-13 T 29-03-2018 GBCGDNIH2_RS09215 b8bd7d1e9beda009de32fc34da775fdd 155 Pfam PF07963 Prokaryotic N-terminal methylation motif 10 35 1.3E-8 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site GBCGDNIH2_RS09215 b8bd7d1e9beda009de32fc34da775fdd 155 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 13 33 - T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site GBCGDNIH2_RS09215 b8bd7d1e9beda009de32fc34da775fdd 155 Gene3D G3DSA:3.30.700.10 15 154 3.8E-6 T 29-03-2018 GBCGDNIH2_RS09215 b8bd7d1e9beda009de32fc34da775fdd 155 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 13 35 1.3E-7 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site GBCGDNIH2_RS09215 b8bd7d1e9beda009de32fc34da775fdd 155 Pfam PF12019 Type II transport protein GspH 50 145 5.7E-6 T 29-03-2018 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 GBCGDNIH2_RS09215 b8bd7d1e9beda009de32fc34da775fdd 155 TIGRFAM TIGR01708 typeII_sec_gspH: type II secretion system protein H 10 147 2.4E-13 T 29-03-2018 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 GBCGDNIH2_RS00890 cd406fb8c8988f9741e509ba0076321c 459 Gene3D G3DSA:3.50.50.60 50 156 4.3E-4 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS00890 cd406fb8c8988f9741e509ba0076321c 459 SUPERFAMILY SSF51905 75 295 7.51E-52 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS00890 cd406fb8c8988f9741e509ba0076321c 459 SUPERFAMILY SSF51905 385 445 7.51E-52 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS00890 cd406fb8c8988f9741e509ba0076321c 459 Pfam PF01266 FAD dependent oxidoreductase 76 423 6.5E-60 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 GBCGDNIH2_RS00890 cd406fb8c8988f9741e509ba0076321c 459 TIGRFAM TIGR01373 soxB: sarcosine oxidase, beta subunit family 45 449 9.2E-208 T 29-03-2018 IPR006278 Sarcosine oxidase subunit beta GO:0008115|GO:0046653|GO:0055114 KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 GBCGDNIH2_RS00890 cd406fb8c8988f9741e509ba0076321c 459 Gene3D G3DSA:3.30.9.10 157 234 3.1E-8 T 29-03-2018 GBCGDNIH2_RS00890 cd406fb8c8988f9741e509ba0076321c 459 SUPERFAMILY SSF54373 313 381 2.55E-6 T 29-03-2018 GBCGDNIH2_RS00890 cd406fb8c8988f9741e509ba0076321c 459 Gene3D G3DSA:3.50.50.60 374 455 6.2E-7 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS00890 cd406fb8c8988f9741e509ba0076321c 459 Gene3D G3DSA:3.30.9.10 235 373 1.0E-23 T 29-03-2018 GBCGDNIH2_RS06315 32fedcacdf3dfc7803dd8b4b97b091a3 261 SUPERFAMILY SSF53474 13 255 1.5E-40 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS06315 32fedcacdf3dfc7803dd8b4b97b091a3 261 Gene3D G3DSA:3.40.50.1820 12 256 5.3E-32 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS06315 32fedcacdf3dfc7803dd8b4b97b091a3 261 Pfam PF12697 Alpha/beta hydrolase family 22 243 2.5E-14 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 GBCGDNIH2_RS00725 4b2111fc86fc9186ecb610886aae4c17 199 TIGRFAM TIGR02081 metW: methionine biosynthesis protein MetW 2 196 1.1E-69 T 29-03-2018 IPR010743 Methionine biosynthesis MetW GBCGDNIH2_RS00725 4b2111fc86fc9186ecb610886aae4c17 199 Gene3D G3DSA:3.40.50.150 3 193 1.3E-22 T 29-03-2018 GBCGDNIH2_RS00725 4b2111fc86fc9186ecb610886aae4c17 199 SUPERFAMILY SSF53335 4 169 1.86E-27 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GBCGDNIH2_RS00725 4b2111fc86fc9186ecb610886aae4c17 199 Pfam PF07021 Methionine biosynthesis protein MetW 2 196 3.3E-73 T 29-03-2018 IPR010743 Methionine biosynthesis MetW GBCGDNIH2_RS07390 77208a8fa656adc4f6cf034d2359ef11 162 Gene3D G3DSA:3.60.90.10 37 161 2.5E-39 T 29-03-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 GBCGDNIH2_RS07390 77208a8fa656adc4f6cf034d2359ef11 162 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 51 159 3.6E-40 T 29-03-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 GBCGDNIH2_RS07390 77208a8fa656adc4f6cf034d2359ef11 162 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 49 160 25.314 T 29-03-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 GBCGDNIH2_RS07390 77208a8fa656adc4f6cf034d2359ef11 162 SUPERFAMILY SSF56276 51 161 3.22E-34 T 29-03-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 GBCGDNIH2_RS07390 77208a8fa656adc4f6cf034d2359ef11 162 Pfam PF02675 S-adenosylmethionine decarboxylase 55 159 2.2E-35 T 29-03-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 GBCGDNIH2_RS10725 85ffd1d22d99315f72c99e8700aa3f29 184 PRINTS PR00125 ATP synthase delta subunit signature 155 173 2.4E-25 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 GBCGDNIH2_RS10725 85ffd1d22d99315f72c99e8700aa3f29 184 PRINTS PR00125 ATP synthase delta subunit signature 79 90 2.4E-25 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 GBCGDNIH2_RS10725 85ffd1d22d99315f72c99e8700aa3f29 184 PRINTS PR00125 ATP synthase delta subunit signature 9 28 2.4E-25 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 GBCGDNIH2_RS10725 85ffd1d22d99315f72c99e8700aa3f29 184 PRINTS PR00125 ATP synthase delta subunit signature 90 104 2.4E-25 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 GBCGDNIH2_RS10725 85ffd1d22d99315f72c99e8700aa3f29 184 PRINTS PR00125 ATP synthase delta subunit signature 140 155 2.4E-25 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 GBCGDNIH2_RS10725 85ffd1d22d99315f72c99e8700aa3f29 184 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 142 161 - T 29-03-2018 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 GBCGDNIH2_RS10725 85ffd1d22d99315f72c99e8700aa3f29 184 Gene3D G3DSA:1.10.520.20 4 111 1.0E-19 T 29-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 GBCGDNIH2_RS10725 85ffd1d22d99315f72c99e8700aa3f29 184 Pfam PF00213 ATP synthase delta (OSCP) subunit 9 179 3.4E-43 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 GBCGDNIH2_RS10725 85ffd1d22d99315f72c99e8700aa3f29 184 Hamap MF_01416 ATP synthase subunit delta [atpD]. 5 182 18.084 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 GBCGDNIH2_RS10725 85ffd1d22d99315f72c99e8700aa3f29 184 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 10 178 7.1E-31 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 GBCGDNIH2_RS10725 85ffd1d22d99315f72c99e8700aa3f29 184 SUPERFAMILY SSF47928 6 111 1.57E-18 T 29-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 GBCGDNIH2_RS04790 6e90e3487045d00fae452418895fdedb 209 TIGRFAM TIGR01543 proheadase_HK97: phage prohead protease, HK97 family 14 152 2.0E-33 T 29-03-2018 IPR006433 Prohead protease GBCGDNIH2_RS04790 6e90e3487045d00fae452418895fdedb 209 SUPERFAMILY SSF50789 33 151 4.09E-5 T 29-03-2018 GBCGDNIH2_RS04790 6e90e3487045d00fae452418895fdedb 209 Gene3D G3DSA:3.20.16.10 10 199 1.2E-40 T 29-03-2018 IPR035443 Herpesvirus/Caudovirus protease domain GBCGDNIH2_RS04790 6e90e3487045d00fae452418895fdedb 209 Pfam PF04586 Caudovirus prohead serine protease 6 155 1.1E-30 T 29-03-2018 IPR006433 Prohead protease GBCGDNIH2_RS05935 ade7d226b4728d5b6b792381d98fb057 249 Pfam PF01709 Transcriptional regulator 5 237 1.7E-89 T 29-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS05935 ade7d226b4728d5b6b792381d98fb057 249 SUPERFAMILY SSF75625 3 246 6.15E-89 T 29-03-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS05935 ade7d226b4728d5b6b792381d98fb057 249 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 239 34.076 T 29-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS05935 ade7d226b4728d5b6b792381d98fb057 249 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 237 2.9E-93 T 29-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS05935 ade7d226b4728d5b6b792381d98fb057 249 Gene3D G3DSA:3.30.70.980 83 178 3.9E-33 T 29-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS05935 ade7d226b4728d5b6b792381d98fb057 249 Gene3D G3DSA:3.30.70.980 180 238 2.9E-6 T 29-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS05935 ade7d226b4728d5b6b792381d98fb057 249 Gene3D G3DSA:1.10.10.200 1 78 1.8E-29 T 29-03-2018 IPR017856 Integrase, N-terminal zinc-binding domain-like GBCGDNIH2_RS01175 a810fe0429d84c4b9e845c1e43cf1e13 340 TIGRFAM TIGR03476 HpnL: putative membrane protein 5 312 4.4E-77 T 29-03-2018 GBCGDNIH2_RS01175 a810fe0429d84c4b9e845c1e43cf1e13 340 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 5 298 2.3E-25 T 29-03-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD GBCGDNIH2_RS02030 2d1f687dce1d03d3e3d5e38bca233aa6 521 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 24 501 18.283 T 29-03-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 GBCGDNIH2_RS02030 2d1f687dce1d03d3e3d5e38bca233aa6 521 Pfam PF00795 Carbon-nitrogen hydrolase 271 463 7.1E-17 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 GBCGDNIH2_RS02030 2d1f687dce1d03d3e3d5e38bca233aa6 521 Gene3D G3DSA:3.60.110.10 232 482 1.1E-35 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 GBCGDNIH2_RS02030 2d1f687dce1d03d3e3d5e38bca233aa6 521 SUPERFAMILY SSF56317 233 493 4.06E-36 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 GBCGDNIH2_RS02030 2d1f687dce1d03d3e3d5e38bca233aa6 521 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 78 463 3.4E-80 T 29-03-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 GBCGDNIH2_RS11075 92da68308411bf4791f50704912f3cae 365 SUPERFAMILY SSF51395 1 361 1.59E-115 T 29-03-2018 GBCGDNIH2_RS11075 92da68308411bf4791f50704912f3cae 365 Gene3D G3DSA:3.20.20.70 1 364 2.7E-118 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS11075 92da68308411bf4791f50704912f3cae 365 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 6 338 6.1E-80 T 29-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 GBCGDNIH2_RS07495 eca91c4ad66bd47e370cf7754d918f85 157 Gene3D G3DSA:3.30.530.20 16 157 3.8E-29 T 29-03-2018 IPR023393 START-like domain GBCGDNIH2_RS07495 eca91c4ad66bd47e370cf7754d918f85 157 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 22 156 1.4E-35 T 29-03-2018 IPR019587 Polyketide cyclase/dehydrase GBCGDNIH2_RS07495 eca91c4ad66bd47e370cf7754d918f85 157 SUPERFAMILY SSF55961 24 156 4.26E-31 T 29-03-2018 GBCGDNIH2_RS01675 d15924ce1b29746be4143007681df6fa 321 Gene3D G3DSA:3.90.550.10 6 128 8.2E-6 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS01675 d15924ce1b29746be4143007681df6fa 321 SUPERFAMILY SSF53448 7 96 2.67E-6 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS01675 d15924ce1b29746be4143007681df6fa 321 Pfam PF13704 Glycosyl transferase family 2 11 103 1.1E-16 T 29-03-2018 GBCGDNIH2_RS05575 25d6f0580e6141b2fb20a942d2e2eb6b 212 Pfam PF02545 Maf-like protein 11 205 2.9E-47 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 GBCGDNIH2_RS05575 25d6f0580e6141b2fb20a942d2e2eb6b 212 Hamap MF_00528 Septum formation protein Maf [maf]. 10 211 28.988 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 GBCGDNIH2_RS05575 25d6f0580e6141b2fb20a942d2e2eb6b 212 Gene3D G3DSA:3.90.950.10 2 207 9.6E-57 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like GBCGDNIH2_RS05575 25d6f0580e6141b2fb20a942d2e2eb6b 212 TIGRFAM TIGR00172 maf: septum formation protein Maf 10 205 1.5E-40 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 GBCGDNIH2_RS05575 25d6f0580e6141b2fb20a942d2e2eb6b 212 PIRSF PIRSF006305 4 211 4.5E-43 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 GBCGDNIH2_RS05575 25d6f0580e6141b2fb20a942d2e2eb6b 212 SUPERFAMILY SSF52972 9 206 1.11E-50 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like GBCGDNIH2_RS04185 f13b8a967258a130c0de8046841e8c1e 710 Pfam PF03772 Competence protein 243 521 1.3E-59 T 29-03-2018 IPR004477 ComEC/Rec2-related protein GBCGDNIH2_RS04185 f13b8a967258a130c0de8046841e8c1e 710 Pfam PF13567 Domain of unknown function (DUF4131) 51 195 5.2E-11 T 29-03-2018 IPR025405 Domain of unknown function DUF4131 GBCGDNIH2_RS04185 f13b8a967258a130c0de8046841e8c1e 710 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 264 452 6.2E-22 T 29-03-2018 IPR004477 ComEC/Rec2-related protein GBCGDNIH2_RS07905 08b9c84e071c700bafd506b4b3a20d28 276 Gene3D G3DSA:3.40.50.300 4 268 2.5E-58 T 29-03-2018 GBCGDNIH2_RS07905 08b9c84e071c700bafd506b4b3a20d28 276 SUPERFAMILY SSF52540 9 264 6.58E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS07905 08b9c84e071c700bafd506b4b3a20d28 276 Pfam PF00005 ABC transporter 26 192 1.2E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GBCGDNIH2_RS07905 08b9c84e071c700bafd506b4b3a20d28 276 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 241 263 7.3E-12 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal GBCGDNIH2_RS07905 08b9c84e071c700bafd506b4b3a20d28 276 SMART SM00382 35 241 3.2E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS07615 312578d5589e1456fae7919e909e69e9 92 Pfam PF07769 psiF repeat 22 53 1.9E-16 T 29-03-2018 IPR011690 Phosphate-starvation-induced PsiF repeat GBCGDNIH2_RS07615 312578d5589e1456fae7919e909e69e9 92 Pfam PF07769 psiF repeat 58 90 7.8E-14 T 29-03-2018 IPR011690 Phosphate-starvation-induced PsiF repeat GBCGDNIH2_RS06915 76fa741f93af49044e7532812f597029 506 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 9 490 1.8E-193 T 29-03-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS06915 76fa741f93af49044e7532812f597029 506 Pfam PF00361 Proton-conducting membrane transporter 136 421 2.4E-86 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS06915 76fa741f93af49044e7532812f597029 506 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 142 161 4.3E-50 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS06915 76fa741f93af49044e7532812f597029 506 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 381 407 4.3E-50 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS06915 76fa741f93af49044e7532812f597029 506 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 241 265 4.3E-50 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS06915 76fa741f93af49044e7532812f597029 506 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 329 348 4.3E-50 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS06915 76fa741f93af49044e7532812f597029 506 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 172 196 4.3E-50 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS04110 cea7d37f598f24a3e0c4668663cf932d 233 SUPERFAMILY SSF47616 77 203 2.32E-36 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like GBCGDNIH2_RS04110 cea7d37f598f24a3e0c4668663cf932d 233 Gene3D G3DSA:1.20.1050.10 143 200 3.3E-15 T 29-03-2018 GBCGDNIH2_RS04110 cea7d37f598f24a3e0c4668663cf932d 233 Gene3D G3DSA:1.20.1050.10 93 142 7.4E-15 T 29-03-2018 GBCGDNIH2_RS04110 cea7d37f598f24a3e0c4668663cf932d 233 Pfam PF00043 Glutathione S-transferase, C-terminal domain 110 196 2.6E-13 T 29-03-2018 IPR004046 Glutathione S-transferase, C-terminal GBCGDNIH2_RS04110 cea7d37f598f24a3e0c4668663cf932d 233 SUPERFAMILY SSF52833 1 83 2.56E-23 T 29-03-2018 IPR012336 Thioredoxin-like fold GBCGDNIH2_RS04110 cea7d37f598f24a3e0c4668663cf932d 233 Gene3D G3DSA:3.40.30.10 1 92 5.7E-26 T 29-03-2018 GBCGDNIH2_RS04110 cea7d37f598f24a3e0c4668663cf932d 233 Pfam PF02798 Glutathione S-transferase, N-terminal domain 3 80 6.3E-15 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 GBCGDNIH2_RS03845 33c52d05c57d0e17ddbb8d4ae9f30e19 497 SUPERFAMILY SSF53756 2 452 6.91E-132 T 29-03-2018 GBCGDNIH2_RS03845 33c52d05c57d0e17ddbb8d4ae9f30e19 497 Gene3D G3DSA:3.40.50.2000 239 438 2.2E-39 T 29-03-2018 GBCGDNIH2_RS03845 33c52d05c57d0e17ddbb8d4ae9f30e19 497 Gene3D G3DSA:3.40.50.2000 1 238 1.8E-64 T 29-03-2018 GBCGDNIH2_RS03845 33c52d05c57d0e17ddbb8d4ae9f30e19 497 Pfam PF00982 Glycosyltransferase family 20 20 452 1.2E-119 T 29-03-2018 IPR001830 Glycosyl transferase, family 20 GO:0003824|GO:0005992 GBCGDNIH2_RS12290 66dce6267bb69d06ce6e99891351573e 321 ProSitePatterns PS01173 Lipolytic enzymes "G-D-X-G" family, putative histidine active site. 90 106 - T 29-03-2018 IPR002168 Lipase, GDXG, putative histidine active site GO:0008152|GO:0016787 Reactome: R-HSA-163560 GBCGDNIH2_RS12290 66dce6267bb69d06ce6e99891351573e 321 Pfam PF07859 alpha/beta hydrolase fold 91 298 2.9E-71 T 29-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 GBCGDNIH2_RS12290 66dce6267bb69d06ce6e99891351573e 321 Gene3D G3DSA:3.40.50.1820 10 321 9.0E-59 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS12290 66dce6267bb69d06ce6e99891351573e 321 SUPERFAMILY SSF53474 49 321 3.42E-72 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS10175 496dcc6d283e4c10a086014cf1ac86d0 184 SUPERFAMILY SSF52309 7 150 2.69E-36 T 29-03-2018 GBCGDNIH2_RS10175 496dcc6d283e4c10a086014cf1ac86d0 184 Gene3D G3DSA:3.40.50.450 2 152 1.0E-27 T 29-03-2018 GBCGDNIH2_RS10175 496dcc6d283e4c10a086014cf1ac86d0 184 Pfam PF05014 Nucleoside 2-deoxyribosyltransferase 8 139 7.5E-37 T 29-03-2018 IPR007710 Nucleoside 2-deoxyribosyltransferase GO:0009159|GO:0050144|GO:0070694 Reactome: R-HSA-74259 GBCGDNIH2_RS11950 38bfb952eb1cc177b260877bbb038006 167 Gene3D G3DSA:3.30.1460.10 16 154 3.4E-4 T 29-03-2018 GBCGDNIH2_RS11950 38bfb952eb1cc177b260877bbb038006 167 Pfam PF10722 Putative bacterial sensory transduction regulator 15 144 1.9E-32 T 29-03-2018 IPR019660 Putative sensory transduction regulator YbjN GBCGDNIH2_RS05800 55760dccd82e4f945de8402ef6a2382e 315 Hamap MF_02071 Endolytic peptidoglycan transglycosylase RlpA [rlpA]. 5 155 17.719 T 29-03-2018 IPR034718 Endolytic peptidoglycan transglycosylase RlpA GO:0016829 GBCGDNIH2_RS05800 55760dccd82e4f945de8402ef6a2382e 315 SUPERFAMILY SSF110997 232 305 1.7E-8 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 GBCGDNIH2_RS05800 55760dccd82e4f945de8402ef6a2382e 315 Pfam PF03330 Lytic transglycolase 81 151 3.5E-11 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain GBCGDNIH2_RS05800 55760dccd82e4f945de8402ef6a2382e 315 Pfam PF05036 Sporulation related domain 233 296 4.1E-6 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 GBCGDNIH2_RS05800 55760dccd82e4f945de8402ef6a2382e 315 Gene3D G3DSA:2.40.40.10 51 155 3.1E-10 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain GBCGDNIH2_RS05800 55760dccd82e4f945de8402ef6a2382e 315 Gene3D G3DSA:3.30.70.1070 231 307 3.6E-7 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 GBCGDNIH2_RS11655 cc175149b6479efdd0c38a1103c9db2e 281 Gene3D G3DSA:1.20.120.80 83 279 1.2E-74 T 29-03-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS11655 cc175149b6479efdd0c38a1103c9db2e 281 Gene3D G3DSA:1.10.287.70 15 82 9.5E-21 T 29-03-2018 GBCGDNIH2_RS11655 cc175149b6479efdd0c38a1103c9db2e 281 SUPERFAMILY SSF81452 17 278 6.54E-92 T 29-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS11655 cc175149b6479efdd0c38a1103c9db2e 281 Pfam PF00510 Cytochrome c oxidase subunit III 19 278 9.5E-89 T 29-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS10975 9e49a91c76ad966e4f78baa9b4042b5e 316 Pfam PF03690 Uncharacterised protein family (UPF0160) 9 312 3.0E-81 T 29-03-2018 IPR003226 Metal-dependent protein hydrolase GBCGDNIH2_RS11685 3da7d4ae27ad5a51209c203e23fb94d9 318 SUPERFAMILY SSF54427 194 317 2.4E-24 T 29-03-2018 IPR032710 NTF2-like domain GBCGDNIH2_RS11685 3da7d4ae27ad5a51209c203e23fb94d9 318 SMART SM00978 174 316 4.2E-29 T 29-03-2018 IPR007379 Tim44-like domain GBCGDNIH2_RS11685 3da7d4ae27ad5a51209c203e23fb94d9 318 Pfam PF04280 Tim44-like domain 193 316 6.5E-26 T 29-03-2018 IPR007379 Tim44-like domain GBCGDNIH2_RS12310 d3c91a874ccf627c1102e38254ecdf8a 210 SMART SM00855 15 165 0.002 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 GBCGDNIH2_RS12310 d3c91a874ccf627c1102e38254ecdf8a 210 Gene3D G3DSA:3.40.50.1240 13 209 2.4E-25 T 29-03-2018 IPR029033 Histidine phosphatase superfamily GBCGDNIH2_RS12310 d3c91a874ccf627c1102e38254ecdf8a 210 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 16 200 2.5E-28 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 GBCGDNIH2_RS12310 d3c91a874ccf627c1102e38254ecdf8a 210 SUPERFAMILY SSF53254 13 200 6.0E-32 T 29-03-2018 IPR029033 Histidine phosphatase superfamily GBCGDNIH2_RS06785 eff5f1f4b64f6fe09988baea666c39f9 139 Pfam PF01521 Iron-sulphur cluster biosynthesis 40 133 2.8E-17 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 GBCGDNIH2_RS06785 eff5f1f4b64f6fe09988baea666c39f9 139 SUPERFAMILY SSF89360 40 127 1.26E-24 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 GBCGDNIH2_RS06785 eff5f1f4b64f6fe09988baea666c39f9 139 Gene3D G3DSA:2.60.300.12 38 139 5.1E-35 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 GBCGDNIH2_RS06785 eff5f1f4b64f6fe09988baea666c39f9 139 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 119 136 - T 29-03-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 GBCGDNIH2_RS06785 eff5f1f4b64f6fe09988baea666c39f9 139 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 42 138 2.0E-32 T 29-03-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 GBCGDNIH2_RS08130 0810c361d2af5e954c13c6b5117e6c60 326 Gene3D G3DSA:3.90.25.10 184 325 8.0E-25 T 29-03-2018 GBCGDNIH2_RS08130 0810c361d2af5e954c13c6b5117e6c60 326 Pfam PF01370 NAD dependent epimerase/dehydratase family 2 247 8.7E-39 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 GBCGDNIH2_RS08130 0810c361d2af5e954c13c6b5117e6c60 326 SUPERFAMILY SSF51735 2 319 1.62E-60 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS08130 0810c361d2af5e954c13c6b5117e6c60 326 Gene3D G3DSA:3.40.50.720 1 183 7.5E-20 T 29-03-2018 GBCGDNIH2_RS08130 0810c361d2af5e954c13c6b5117e6c60 326 TIGRFAM TIGR02197 heptose_epim: ADP-glyceromanno-heptose 6-epimerase 2 319 4.6E-118 T 29-03-2018 IPR011912 ADP-L-glycero-D-manno-heptose-6-epimerase GO:0005975|GO:0008712|GO:0050661 KEGG: 00540+5.1.3.20 GBCGDNIH2_RS08130 0810c361d2af5e954c13c6b5117e6c60 326 Hamap MF_01601 ADP-L-glycero-D-manno-heptose-6-epimerase [hldD]. 1 321 46.041 T 29-03-2018 IPR011912 ADP-L-glycero-D-manno-heptose-6-epimerase GO:0005975|GO:0008712|GO:0050661 KEGG: 00540+5.1.3.20 GBCGDNIH2_RS06000 db427797539ff88b75e55306753450e3 641 Pfam PF06480 FtsH Extracellular 9 96 2.6E-12 T 29-03-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 GBCGDNIH2_RS06000 db427797539ff88b75e55306753450e3 641 Pfam PF01434 Peptidase family M41 386 594 2.3E-82 T 29-03-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 GBCGDNIH2_RS06000 db427797539ff88b75e55306753450e3 641 SUPERFAMILY SSF52540 146 395 3.72E-73 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS06000 db427797539ff88b75e55306753450e3 641 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 105 597 1.0E-240 T 29-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 GBCGDNIH2_RS06000 db427797539ff88b75e55306753450e3 641 Gene3D G3DSA:1.10.8.60 336 418 6.1E-26 T 29-03-2018 GBCGDNIH2_RS06000 db427797539ff88b75e55306753450e3 641 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 6 615 37.824 T 29-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 GBCGDNIH2_RS06000 db427797539ff88b75e55306753450e3 641 SUPERFAMILY SSF140990 406 600 4.19E-74 T 29-03-2018 GBCGDNIH2_RS06000 db427797539ff88b75e55306753450e3 641 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 192 324 1.3E-45 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 GBCGDNIH2_RS06000 db427797539ff88b75e55306753450e3 641 Gene3D G3DSA:3.40.50.300 134 335 5.9E-62 T 29-03-2018 GBCGDNIH2_RS06000 db427797539ff88b75e55306753450e3 641 SMART SM00382 188 327 1.6E-25 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS06000 db427797539ff88b75e55306753450e3 641 ProSitePatterns PS00674 AAA-protein family signature. 295 313 - T 29-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 GBCGDNIH2_RS04480 a19ebfcf368d6e3fd64d6d26d1aaa58b 554 SMART SM00382 353 539 7.8E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS04480 a19ebfcf368d6e3fd64d6d26d1aaa58b 554 ProSitePatterns PS00211 ABC transporters family signature. 465 479 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GBCGDNIH2_RS04480 a19ebfcf368d6e3fd64d6d26d1aaa58b 554 Pfam PF00664 ABC transporter transmembrane region 16 255 8.3E-19 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 GBCGDNIH2_RS04480 a19ebfcf368d6e3fd64d6d26d1aaa58b 554 SUPERFAMILY SSF90123 14 311 1.06E-36 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 GBCGDNIH2_RS04480 a19ebfcf368d6e3fd64d6d26d1aaa58b 554 Gene3D G3DSA:1.20.1560.10 9 312 1.4E-27 T 29-03-2018 GBCGDNIH2_RS04480 a19ebfcf368d6e3fd64d6d26d1aaa58b 554 Gene3D G3DSA:3.40.50.300 313 547 4.5E-62 T 29-03-2018 GBCGDNIH2_RS04480 a19ebfcf368d6e3fd64d6d26d1aaa58b 554 SUPERFAMILY SSF52540 322 542 1.33E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS04480 a19ebfcf368d6e3fd64d6d26d1aaa58b 554 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 9 525 2.5E-150 T 29-03-2018 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 GBCGDNIH2_RS04480 a19ebfcf368d6e3fd64d6d26d1aaa58b 554 Pfam PF00005 ABC transporter 344 493 4.3E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GBCGDNIH2_RS06490 9fb8d6e6e5b1ada23e3aa082bf49c98b 149 ProSitePatterns PS00893 Nudix box signature. 47 68 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 GBCGDNIH2_RS06490 9fb8d6e6e5b1ada23e3aa082bf49c98b 149 Pfam PF00293 NUDIX domain 15 125 7.4E-18 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 GBCGDNIH2_RS06490 9fb8d6e6e5b1ada23e3aa082bf49c98b 149 PRINTS PR00502 NUDIX hydrolase family signature 42 56 1.4E-6 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 GBCGDNIH2_RS06490 9fb8d6e6e5b1ada23e3aa082bf49c98b 149 PRINTS PR00502 NUDIX hydrolase family signature 56 71 1.4E-6 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 GBCGDNIH2_RS06490 9fb8d6e6e5b1ada23e3aa082bf49c98b 149 SUPERFAMILY SSF55811 3 143 2.3E-28 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 GBCGDNIH2_RS06490 9fb8d6e6e5b1ada23e3aa082bf49c98b 149 Gene3D G3DSA:3.90.79.10 1 146 5.8E-26 T 29-03-2018 GBCGDNIH2_RS05655 b90e2ff0086e8b2c9caf8ee546bf71d2 498 SUPERFAMILY SSF51905 8 327 1.4E-26 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS05655 b90e2ff0086e8b2c9caf8ee546bf71d2 498 Hamap MF_00212 Probable malate:quinone oxidoreductase [mqo]. 5 495 48.327 T 29-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 GBCGDNIH2_RS05655 b90e2ff0086e8b2c9caf8ee546bf71d2 498 Gene3D G3DSA:3.50.50.60 1 481 2.0E-21 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS05655 b90e2ff0086e8b2c9caf8ee546bf71d2 498 Pfam PF06039 Malate:quinone oxidoreductase (Mqo) 9 494 2.8E-225 T 29-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 GBCGDNIH2_RS05655 b90e2ff0086e8b2c9caf8ee546bf71d2 498 TIGRFAM TIGR01320 mal_quin_oxido: malate dehydrogenase (acceptor) 10 493 7.1E-199 T 29-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 GBCGDNIH2_RS08805 5bb63bda5e81540fc73e134602cfd06c 111 SUPERFAMILY SSF52833 1 105 3.31E-36 T 29-03-2018 IPR012336 Thioredoxin-like fold GBCGDNIH2_RS08805 5bb63bda5e81540fc73e134602cfd06c 111 PIRSF PIRSF005894 1 108 1.1E-49 T 29-03-2018 IPR014434 Monothiol glutaredoxin GO:0015036 Reactome: R-HSA-1362409 GBCGDNIH2_RS08805 5bb63bda5e81540fc73e134602cfd06c 111 Pfam PF00462 Glutaredoxin 17 81 1.8E-18 T 29-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 GBCGDNIH2_RS08805 5bb63bda5e81540fc73e134602cfd06c 111 Gene3D G3DSA:3.40.30.10 2 111 7.8E-34 T 29-03-2018 GBCGDNIH2_RS08805 5bb63bda5e81540fc73e134602cfd06c 111 TIGRFAM TIGR00365 TIGR00365: monothiol glutaredoxin, Grx4 family 5 101 1.4E-46 T 29-03-2018 IPR004480 Monothiol glutaredoxin-related GBCGDNIH2_RS06285 815e4d12113ebd1cc558f803d970b5a5 287 Gene3D G3DSA:3.60.15.10 1 285 3.3E-53 T 29-03-2018 IPR001279 Metallo-beta-lactamase GBCGDNIH2_RS06285 815e4d12113ebd1cc558f803d970b5a5 287 SUPERFAMILY SSF56281 5 277 1.83E-50 T 29-03-2018 IPR001279 Metallo-beta-lactamase GBCGDNIH2_RS06285 815e4d12113ebd1cc558f803d970b5a5 287 Pfam PF00753 Metallo-beta-lactamase superfamily 55 257 4.3E-25 T 29-03-2018 IPR001279 Metallo-beta-lactamase GBCGDNIH2_RS06285 815e4d12113ebd1cc558f803d970b5a5 287 SMART SM00849 55 257 3.1E-29 T 29-03-2018 IPR001279 Metallo-beta-lactamase GBCGDNIH2_RS03590 d67290da00eef5513a7a2029c7972dc4 320 Pfam PF01370 NAD dependent epimerase/dehydratase family 7 215 2.8E-12 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 GBCGDNIH2_RS03590 d67290da00eef5513a7a2029c7972dc4 320 SUPERFAMILY SSF51735 1 270 8.48E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS03590 d67290da00eef5513a7a2029c7972dc4 320 Gene3D G3DSA:3.40.50.720 1 311 3.3E-39 T 29-03-2018 GBCGDNIH2_RS00250 1eecccc0e1a5e14ad00f0992b945a372 290 Gene3D G3DSA:3.40.50.10280 3 113 2.7E-42 T 29-03-2018 IPR015259 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal GBCGDNIH2_RS00250 1eecccc0e1a5e14ad00f0992b945a372 290 SUPERFAMILY SSF53223 3 97 1.38E-32 T 29-03-2018 GBCGDNIH2_RS00250 1eecccc0e1a5e14ad00f0992b945a372 290 Pfam PF09176 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal 17 97 2.2E-31 T 29-03-2018 IPR015259 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal GBCGDNIH2_RS00250 1eecccc0e1a5e14ad00f0992b945a372 290 Gene3D G3DSA:3.40.50.720 114 249 3.0E-12 T 29-03-2018 GBCGDNIH2_RS00250 1eecccc0e1a5e14ad00f0992b945a372 290 SUPERFAMILY SSF51735 111 217 1.59E-15 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS08380 9989400fb20d3eae59de3512dabc269f 476 Pfam PF17289 Terminase RNaseH-like domain 312 461 2.4E-14 T 29-03-2018 IPR035421 Terminase, large subunit gp17-like GBCGDNIH2_RS08380 9989400fb20d3eae59de3512dabc269f 476 TIGRFAM TIGR01630 psiM2_ORF9: phage uncharacterized protein, C-terminal domain 327 462 3.8E-20 T 29-03-2018 IPR006517 Archaeophage PsiM2, terminase large subunit GBCGDNIH2_RS08380 9989400fb20d3eae59de3512dabc269f 476 Gene3D G3DSA:3.40.50.300 52 455 2.1E-4 T 29-03-2018 GBCGDNIH2_RS00225 fcabad93a9628c1b3ae6d76a719e0a1a 114 SUPERFAMILY SSF81296 15 109 2.66E-16 T 29-03-2018 IPR014756 Immunoglobulin E-set GBCGDNIH2_RS00225 fcabad93a9628c1b3ae6d76a719e0a1a 114 Gene3D G3DSA:2.60.40.1220 15 110 6.3E-16 T 29-03-2018 GBCGDNIH2_RS00225 fcabad93a9628c1b3ae6d76a719e0a1a 114 Pfam PF04234 CopC domain 16 109 4.9E-16 T 29-03-2018 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 GBCGDNIH2_RS05050 8c04b20890f73ee620b623c0fe9e993b 257 Gene3D G3DSA:3.40.50.720 1 257 2.7E-49 T 29-03-2018 GBCGDNIH2_RS05050 8c04b20890f73ee620b623c0fe9e993b 257 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 255 1.3E-41 T 29-03-2018 GBCGDNIH2_RS05050 8c04b20890f73ee620b623c0fe9e993b 257 SUPERFAMILY SSF51735 7 255 2.94E-51 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS05050 8c04b20890f73ee620b623c0fe9e993b 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 3.5E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS05050 8c04b20890f73ee620b623c0fe9e993b 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 3.5E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS05050 8c04b20890f73ee620b623c0fe9e993b 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 3.5E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS05050 8c04b20890f73ee620b623c0fe9e993b 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 3.5E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS05050 8c04b20890f73ee620b623c0fe9e993b 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 3.5E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS05970 5442eb744a4e91206b6cae1a2587bcf5 164 Pfam PF02472 Biopolymer transport protein ExbD/TolR 17 139 4.6E-32 T 29-03-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS05970 5442eb744a4e91206b6cae1a2587bcf5 164 TIGRFAM TIGR02801 tolR: protein TolR 19 139 3.7E-42 T 29-03-2018 IPR014168 Biopolymer transport, TolR GO:0015031|GO:0016021 GBCGDNIH2_RS05310 5f437dd4203daa1f4151c1b2095cc804 430 Pfam PF03471 Transporter associated domain 350 424 7.4E-19 T 29-03-2018 IPR005170 Transporter-associated domain GBCGDNIH2_RS05310 5f437dd4203daa1f4151c1b2095cc804 430 SMART SM00116 222 271 0.65 T 29-03-2018 IPR000644 CBS domain GBCGDNIH2_RS05310 5f437dd4203daa1f4151c1b2095cc804 430 SMART SM00116 284 332 3.0 T 29-03-2018 IPR000644 CBS domain GBCGDNIH2_RS05310 5f437dd4203daa1f4151c1b2095cc804 430 Pfam PF01595 Domain of unknown function DUF21 6 198 3.0E-46 T 29-03-2018 IPR002550 Domain of unknown function DUF21 GBCGDNIH2_RS05310 5f437dd4203daa1f4151c1b2095cc804 430 SUPERFAMILY SSF56176 351 424 2.67E-16 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 GBCGDNIH2_RS05310 5f437dd4203daa1f4151c1b2095cc804 430 SUPERFAMILY SSF54631 201 334 1.95E-23 T 29-03-2018 GBCGDNIH2_RS05310 5f437dd4203daa1f4151c1b2095cc804 430 Gene3D G3DSA:3.20.20.70 159 350 2.0E-24 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS05310 5f437dd4203daa1f4151c1b2095cc804 430 Pfam PF00571 CBS domain 283 332 5.3E-4 T 29-03-2018 IPR000644 CBS domain GBCGDNIH2_RS05310 5f437dd4203daa1f4151c1b2095cc804 430 SMART SM01091 346 426 3.3E-21 T 29-03-2018 IPR005170 Transporter-associated domain GBCGDNIH2_RS05310 5f437dd4203daa1f4151c1b2095cc804 430 Gene3D G3DSA:3.30.465.10 351 426 7.3E-19 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 GBCGDNIH2_RS03935 691534bde8b46f10d43a124c1bb6533d 190 SUPERFAMILY SSF52507 16 168 2.09E-18 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 GBCGDNIH2_RS03935 691534bde8b46f10d43a124c1bb6533d 190 Gene3D G3DSA:3.40.50.1950 11 186 5.2E-23 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 GBCGDNIH2_RS03935 691534bde8b46f10d43a124c1bb6533d 190 Pfam PF02441 Flavoprotein 15 172 5.0E-17 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 GBCGDNIH2_RS07440 de4df35506be7336d38572a8ff717a91 136 Pfam PF00581 Rhodanese-like domain 16 112 6.5E-10 T 29-03-2018 IPR001763 Rhodanese-like domain GBCGDNIH2_RS07440 de4df35506be7336d38572a8ff717a91 136 Gene3D G3DSA:3.40.250.10 1 136 1.1E-21 T 29-03-2018 IPR001763 Rhodanese-like domain GBCGDNIH2_RS07440 de4df35506be7336d38572a8ff717a91 136 SMART SM00450 6 119 1.8E-9 T 29-03-2018 IPR001763 Rhodanese-like domain GBCGDNIH2_RS07440 de4df35506be7336d38572a8ff717a91 136 SUPERFAMILY SSF52821 4 135 8.64E-21 T 29-03-2018 IPR001763 Rhodanese-like domain GBCGDNIH2_RS01810 dd139dae806095a67237ecb4f6d76b45 287 Gene3D G3DSA:3.40.50.410 48 234 2.4E-14 T 29-03-2018 IPR002035 von Willebrand factor, type A GBCGDNIH2_RS01810 dd139dae806095a67237ecb4f6d76b45 287 Pfam PF01882 Protein of unknown function DUF58 44 121 1.3E-6 T 29-03-2018 IPR002881 Domain of unknown function DUF58 GBCGDNIH2_RS01810 dd139dae806095a67237ecb4f6d76b45 287 SUPERFAMILY SSF53300 78 196 1.07E-5 T 29-03-2018 IPR002035 von Willebrand factor, type A GBCGDNIH2_RS01295 73155b4c06f5ee0d41e1c5c00541fccd 811 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 686 806 4.0E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS01295 73155b4c06f5ee0d41e1c5c00541fccd 811 Pfam PF08447 PAS fold 438 521 4.8E-18 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 GBCGDNIH2_RS01295 73155b4c06f5ee0d41e1c5c00541fccd 811 Pfam PF08447 PAS fold 312 402 7.9E-8 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 GBCGDNIH2_RS01295 73155b4c06f5ee0d41e1c5c00541fccd 811 Gene3D G3DSA:3.30.450.20 283 414 3.2E-17 T 29-03-2018 GBCGDNIH2_RS01295 73155b4c06f5ee0d41e1c5c00541fccd 811 SMART SM00387 685 808 3.3E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS01295 73155b4c06f5ee0d41e1c5c00541fccd 811 SMART SM00091 170 240 24.0 T 29-03-2018 IPR000014 PAS domain GBCGDNIH2_RS01295 73155b4c06f5ee0d41e1c5c00541fccd 811 SMART SM00091 289 355 7.6 T 29-03-2018 IPR000014 PAS domain GBCGDNIH2_RS01295 73155b4c06f5ee0d41e1c5c00541fccd 811 SMART SM00091 414 480 2.5E-7 T 29-03-2018 IPR000014 PAS domain GBCGDNIH2_RS01295 73155b4c06f5ee0d41e1c5c00541fccd 811 SMART SM00388 576 644 2.1E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GBCGDNIH2_RS01295 73155b4c06f5ee0d41e1c5c00541fccd 811 Gene3D G3DSA:3.30.565.10 643 807 3.2E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS01295 73155b4c06f5ee0d41e1c5c00541fccd 811 Pfam PF00512 His Kinase A (phospho-acceptor) domain 577 642 7.3E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GBCGDNIH2_RS01295 73155b4c06f5ee0d41e1c5c00541fccd 811 SUPERFAMILY SSF55874 634 807 7.99E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS01295 73155b4c06f5ee0d41e1c5c00541fccd 811 SUPERFAMILY SSF47384 567 641 7.65E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GBCGDNIH2_RS01295 73155b4c06f5ee0d41e1c5c00541fccd 811 SUPERFAMILY SSF55785 419 527 2.09E-25 T 29-03-2018 IPR000014 PAS domain GBCGDNIH2_RS01295 73155b4c06f5ee0d41e1c5c00541fccd 811 SMART SM00086 486 529 4.8E-6 T 29-03-2018 IPR001610 PAC motif GBCGDNIH2_RS01295 73155b4c06f5ee0d41e1c5c00541fccd 811 SMART SM00086 368 409 0.01 T 29-03-2018 IPR001610 PAC motif GBCGDNIH2_RS01295 73155b4c06f5ee0d41e1c5c00541fccd 811 Gene3D G3DSA:3.30.450.20 415 557 2.2E-29 T 29-03-2018 GBCGDNIH2_RS01295 73155b4c06f5ee0d41e1c5c00541fccd 811 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 416 534 6.8E-16 T 29-03-2018 IPR000014 PAS domain GBCGDNIH2_RS01295 73155b4c06f5ee0d41e1c5c00541fccd 811 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 294 416 1.4E-6 T 29-03-2018 IPR000014 PAS domain GBCGDNIH2_RS01295 73155b4c06f5ee0d41e1c5c00541fccd 811 Gene3D G3DSA:1.10.287.130 564 640 4.4E-12 T 29-03-2018 GBCGDNIH2_RS01295 73155b4c06f5ee0d41e1c5c00541fccd 811 SUPERFAMILY SSF55785 294 411 1.92E-15 T 29-03-2018 IPR000014 PAS domain GBCGDNIH2_RS01295 73155b4c06f5ee0d41e1c5c00541fccd 811 PRINTS PR00344 Bacterial sensor protein C-terminal signature 792 805 4.3E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS01295 73155b4c06f5ee0d41e1c5c00541fccd 811 PRINTS PR00344 Bacterial sensor protein C-terminal signature 738 752 4.3E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS01295 73155b4c06f5ee0d41e1c5c00541fccd 811 PRINTS PR00344 Bacterial sensor protein C-terminal signature 756 766 4.3E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS01295 73155b4c06f5ee0d41e1c5c00541fccd 811 PRINTS PR00344 Bacterial sensor protein C-terminal signature 768 786 4.3E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GBCGDNIH2_RS01295 73155b4c06f5ee0d41e1c5c00541fccd 811 Gene3D G3DSA:3.30.450.20 141 272 2.0E-4 T 29-03-2018 GBCGDNIH2_RS06040 6468d44268d513d166239bb98d03c03f 249 Pfam PF06299 Protein of unknown function (DUF1045) 79 236 6.4E-51 T 29-03-2018 IPR009389 Protein of unknown function DUF1045 KEGG: 00030+2.7.4.23|MetaCyc: PWY-7805|MetaCyc: PWY-7807 GBCGDNIH2_RS06040 6468d44268d513d166239bb98d03c03f 249 TIGRFAM TIGR03223 Phn_opern_protn: putative phosphonate metabolism protein 20 245 9.3E-77 T 29-03-2018 IPR009389 Protein of unknown function DUF1045 KEGG: 00030+2.7.4.23|MetaCyc: PWY-7805|MetaCyc: PWY-7807 GBCGDNIH2_RS06040 6468d44268d513d166239bb98d03c03f 249 PIRSF PIRSF033328 19 249 1.1E-51 T 29-03-2018 IPR009389 Protein of unknown function DUF1045 KEGG: 00030+2.7.4.23|MetaCyc: PWY-7805|MetaCyc: PWY-7807 GBCGDNIH2_RS06040 6468d44268d513d166239bb98d03c03f 249 Gene3D G3DSA:3.90.1140.10 15 249 7.3E-16 T 29-03-2018 GBCGDNIH2_RS06955 134940ea2a0ac17fafd7bde06521f4d7 227 PIRSF PIRSF000216 11 225 2.0E-65 T 29-03-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS06955 134940ea2a0ac17fafd7bde06521f4d7 227 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 31 182 3.1E-54 T 29-03-2018 GBCGDNIH2_RS06955 134940ea2a0ac17fafd7bde06521f4d7 227 ProSitePatterns PS01099 Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. 140 158 - T 29-03-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS06955 134940ea2a0ac17fafd7bde06521f4d7 227 Gene3D G3DSA:3.40.30.10 100 201 9.4E-13 T 29-03-2018 GBCGDNIH2_RS06955 134940ea2a0ac17fafd7bde06521f4d7 227 TIGRFAM TIGR01958 nuoE_fam: NADH-quinone oxidoreductase, E subunit 30 182 9.0E-48 T 29-03-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS06955 134940ea2a0ac17fafd7bde06521f4d7 227 SUPERFAMILY SSF52833 26 196 8.16E-51 T 29-03-2018 IPR012336 Thioredoxin-like fold GBCGDNIH2_RS04870 41e488a18de82fee8695d90dcd487cb0 368 Gene3D G3DSA:1.10.10.10 261 368 1.6E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS04870 41e488a18de82fee8695d90dcd487cb0 368 Pfam PF13884 Chaperone of endosialidase 273 325 2.9E-5 T 29-03-2018 IPR030392 Intramolecular chaperone auto-processing domain GBCGDNIH2_RS11005 2bb97db72280eefa81d03863cf0d23c2 132 Pfam PF02635 DsrE/DsrF-like family 22 125 1.0E-4 T 29-03-2018 IPR003787 Sulphur relay, DsrE/F-like protein GBCGDNIH2_RS11005 2bb97db72280eefa81d03863cf0d23c2 132 SUPERFAMILY SSF75169 12 128 3.92E-10 T 29-03-2018 IPR027396 DsrEFH-like GBCGDNIH2_RS11005 2bb97db72280eefa81d03863cf0d23c2 132 Gene3D G3DSA:3.40.1260.10 3 132 6.7E-18 T 29-03-2018 GBCGDNIH2_RS04845 15183c82c7343ffc3142bc622961ae78 84 Pfam PF07927 HicA toxin of bacterial toxin-antitoxin, 23 72 1.5E-10 T 29-03-2018 IPR012933 HicA mRNA interferase family GO:0003729 GBCGDNIH2_RS04845 15183c82c7343ffc3142bc622961ae78 84 Gene3D G3DSA:3.30.920.30 18 74 3.7E-4 T 29-03-2018 GBCGDNIH2_RS09990 17cb2e498d90fe7ba35c9facf24d376a 324 Gene3D G3DSA:3.40.190.10 134 307 2.6E-13 T 29-03-2018 GBCGDNIH2_RS09990 17cb2e498d90fe7ba35c9facf24d376a 324 SUPERFAMILY SSF53850 40 246 1.51E-17 T 29-03-2018 GBCGDNIH2_RS09990 17cb2e498d90fe7ba35c9facf24d376a 324 Gene3D G3DSA:3.40.190.10 46 133 8.6E-6 T 29-03-2018 GBCGDNIH2_RS04465 7f7ae70fc50de5ac7739fbe0c19ce817 290 Pfam PF02673 Bacitracin resistance protein BacA 6 281 5.7E-72 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 GBCGDNIH2_RS04465 7f7ae70fc50de5ac7739fbe0c19ce817 290 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 1 287 15.471 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 GBCGDNIH2_RS08075 814fecb06ef7fdbc58fa80842d79e426 353 Pfam PF14350 Beta protein 9 336 9.4E-75 T 29-03-2018 IPR025683 Protein beta GBCGDNIH2_RS03810 e12dd1b1dea469f72b3131675f3fcb89 383 Pfam PF01063 Amino-transferase class IV 87 330 7.2E-37 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 GBCGDNIH2_RS03810 e12dd1b1dea469f72b3131675f3fcb89 383 Gene3D G3DSA:3.20.10.10 193 357 2.0E-50 T 29-03-2018 GBCGDNIH2_RS03810 e12dd1b1dea469f72b3131675f3fcb89 383 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 61 371 2.7E-113 T 29-03-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 GBCGDNIH2_RS03810 e12dd1b1dea469f72b3131675f3fcb89 383 Gene3D G3DSA:3.30.470.10 16 192 1.5E-67 T 29-03-2018 GBCGDNIH2_RS03810 e12dd1b1dea469f72b3131675f3fcb89 383 SUPERFAMILY SSF56752 27 371 1.07E-111 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 GBCGDNIH2_RS03810 e12dd1b1dea469f72b3131675f3fcb89 383 PIRSF PIRSF006468 20 376 1.0E-126 T 29-03-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 GBCGDNIH2_RS05125 1a7969f2e9fddc3ae5b9a7d08f88d51d 303 SMART SM00935 84 238 6.7E-29 T 29-03-2018 IPR005632 Chaperone protein Skp GO:0051082 GBCGDNIH2_RS05125 1a7969f2e9fddc3ae5b9a7d08f88d51d 303 Pfam PF03938 Outer membrane protein (OmpH-like) 96 237 5.9E-17 T 29-03-2018 IPR005632 Chaperone protein Skp GO:0051082 GBCGDNIH2_RS05125 1a7969f2e9fddc3ae5b9a7d08f88d51d 303 SUPERFAMILY SSF111384 99 238 1.96E-18 T 29-03-2018 IPR024930 Skp domain GBCGDNIH2_RS05125 1a7969f2e9fddc3ae5b9a7d08f88d51d 303 Gene3D G3DSA:3.30.910.20 87 152 2.0E-5 T 29-03-2018 GBCGDNIH2_RS05125 1a7969f2e9fddc3ae5b9a7d08f88d51d 303 Gene3D G3DSA:3.30.910.20 153 238 2.5E-11 T 29-03-2018 GBCGDNIH2_RS09960 46a443e885c38698f2bc4f62c753ae21 519 SUPERFAMILY SSF55874 315 453 2.34E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS09960 46a443e885c38698f2bc4f62c753ae21 519 Pfam PF07730 Histidine kinase 234 290 5.3E-5 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 GBCGDNIH2_RS09960 46a443e885c38698f2bc4f62c753ae21 519 Gene3D G3DSA:3.30.565.10 200 455 7.4E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain GBCGDNIH2_RS09960 46a443e885c38698f2bc4f62c753ae21 519 SMART SM00304 166 218 2.7E-4 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 GBCGDNIH2_RS00500 1fdbe4d22f0c250820f8cbadba31844a 343 SUPERFAMILY SSF51735 142 316 1.69E-47 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS00500 1fdbe4d22f0c250820f8cbadba31844a 343 Pfam PF00107 Zinc-binding dehydrogenase 177 301 3.9E-28 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 GBCGDNIH2_RS00500 1fdbe4d22f0c250820f8cbadba31844a 343 SUPERFAMILY SSF50129 12 172 5.33E-41 T 29-03-2018 IPR011032 GroES-like GBCGDNIH2_RS00500 1fdbe4d22f0c250820f8cbadba31844a 343 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 33 133 6.8E-9 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 GBCGDNIH2_RS00500 1fdbe4d22f0c250820f8cbadba31844a 343 Gene3D G3DSA:3.90.180.10 1 342 4.1E-84 T 29-03-2018 GBCGDNIH2_RS00500 1fdbe4d22f0c250820f8cbadba31844a 343 SMART SM00829 16 339 5.3E-27 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 GBCGDNIH2_RS06850 31fe8e5e8b90ef64d72eb7df2ca6bd3b 312 PIRSF PIRSF000292 24 312 2.1E-129 T 29-03-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 GBCGDNIH2_RS06850 31fe8e5e8b90ef64d72eb7df2ca6bd3b 312 Gene3D G3DSA:2.60.40.420 136 301 1.4E-51 T 29-03-2018 IPR008972 Cupredoxin GBCGDNIH2_RS06850 31fe8e5e8b90ef64d72eb7df2ca6bd3b 312 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 170 244 5.1E-7 T 29-03-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS06850 31fe8e5e8b90ef64d72eb7df2ca6bd3b 312 Pfam PF06481 COX Aromatic Rich Motif 260 305 1.0E-17 T 29-03-2018 IPR010514 COX aromatic rich motif GO:0008827|GO:0016021|GO:0022900|GO:0055114 GBCGDNIH2_RS06850 31fe8e5e8b90ef64d72eb7df2ca6bd3b 312 Gene3D G3DSA:1.10.287.90 50 135 4.7E-20 T 29-03-2018 GBCGDNIH2_RS06850 31fe8e5e8b90ef64d72eb7df2ca6bd3b 312 SUPERFAMILY SSF81464 49 139 1.29E-25 T 29-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS06850 31fe8e5e8b90ef64d72eb7df2ca6bd3b 312 SUPERFAMILY SSF49503 141 299 5.11E-49 T 29-03-2018 IPR008972 Cupredoxin GBCGDNIH2_RS06850 31fe8e5e8b90ef64d72eb7df2ca6bd3b 312 TIGRFAM TIGR01433 CyoA: ubiquinol oxidase, subunit II 39 259 5.2E-111 T 29-03-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 GBCGDNIH2_RS04060 4964e2984e62e891968b4af7d756935b 331 SUPERFAMILY SSF48179 197 316 2.21E-29 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 GBCGDNIH2_RS04060 4964e2984e62e891968b4af7d756935b 331 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 197 317 1.3E-27 T 29-03-2018 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 GBCGDNIH2_RS04060 4964e2984e62e891968b4af7d756935b 331 Gene3D G3DSA:3.40.50.720 1 195 1.5E-34 T 29-03-2018 GBCGDNIH2_RS04060 4964e2984e62e891968b4af7d756935b 331 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 168 7.5E-22 T 29-03-2018 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 GBCGDNIH2_RS04060 4964e2984e62e891968b4af7d756935b 331 Gene3D G3DSA:1.10.1040.10 196 325 2.3E-31 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 GBCGDNIH2_RS04060 4964e2984e62e891968b4af7d756935b 331 SUPERFAMILY SSF51735 1 154 1.26E-13 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS07530 00f2851be84860dbea2c71c25b0ca27d 621 SUPERFAMILY SSF51120 445 611 3.66E-9 T 29-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal GBCGDNIH2_RS07530 00f2851be84860dbea2c71c25b0ca27d 621 Gene3D G3DSA:2.150.10.10 444 619 1.1E-11 T 29-03-2018 GBCGDNIH2_RS12045 93234a6325706e3782af9aa12337167c 183 SUPERFAMILY SSF54637 30 174 5.1E-32 T 29-03-2018 IPR029069 HotDog domain GBCGDNIH2_RS12045 93234a6325706e3782af9aa12337167c 183 Pfam PF01575 MaoC like domain 40 138 3.5E-13 T 29-03-2018 IPR002539 MaoC-like domain GBCGDNIH2_RS12045 93234a6325706e3782af9aa12337167c 183 Gene3D G3DSA:3.10.129.10 20 174 2.3E-30 T 29-03-2018 GBCGDNIH2_RS00545 2dfba30cbe21d88bc686b94ae8f7759a 610 Pfam PF13667 ThiC-associated domain 15 83 1.3E-21 T 29-03-2018 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 GBCGDNIH2_RS00545 2dfba30cbe21d88bc686b94ae8f7759a 610 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 124 578 56.023 T 29-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 GBCGDNIH2_RS00545 2dfba30cbe21d88bc686b94ae8f7759a 610 Pfam PF01964 Radical SAM ThiC family 125 572 1.3E-198 T 29-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 GBCGDNIH2_RS00545 2dfba30cbe21d88bc686b94ae8f7759a 610 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 124 575 1.6E-208 T 29-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 GBCGDNIH2_RS06745 0623732ce6e225ef2471986c6a99f355 177 Hamap MF_00237 Sec-independent protein translocase protein TatB [tatB]. 1 166 14.539 T 29-03-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 GBCGDNIH2_RS06745 0623732ce6e225ef2471986c6a99f355 177 Pfam PF02416 mttA/Hcf106 family 6 37 6.8E-5 T 29-03-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 GBCGDNIH2_RS06745 0623732ce6e225ef2471986c6a99f355 177 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 1 21 1.7E-13 T 29-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 GBCGDNIH2_RS06745 0623732ce6e225ef2471986c6a99f355 177 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 21 40 1.7E-13 T 29-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 GBCGDNIH2_RS06745 0623732ce6e225ef2471986c6a99f355 177 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 40 58 1.7E-13 T 29-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 GBCGDNIH2_RS06745 0623732ce6e225ef2471986c6a99f355 177 TIGRFAM TIGR01410 tatB: twin arginine-targeting protein translocase TatB 2 79 1.9E-22 T 29-03-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 GBCGDNIH2_RS09750 5f9fd0e6e4e538f10d4cc5a6f077fe7b 208 SUPERFAMILY SSF52833 41 202 3.43E-34 T 29-03-2018 IPR012336 Thioredoxin-like fold GBCGDNIH2_RS09750 5f9fd0e6e4e538f10d4cc5a6f077fe7b 208 ProSitePatterns PS00194 Thioredoxin family active site. 52 70 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 GBCGDNIH2_RS09750 5f9fd0e6e4e538f10d4cc5a6f077fe7b 208 Gene3D G3DSA:3.40.30.10 38 205 6.9E-32 T 29-03-2018 GBCGDNIH2_RS09750 5f9fd0e6e4e538f10d4cc5a6f077fe7b 208 Pfam PF13462 Thioredoxin 40 203 9.1E-36 T 29-03-2018 IPR012336 Thioredoxin-like fold GBCGDNIH2_RS01680 12e6908998c24904edeb386a3a2299ae 324 Gene3D G3DSA:2.40.70.10 198 317 6.9E-13 T 29-03-2018 IPR021109 Aspartic peptidase domain GBCGDNIH2_RS01680 12e6908998c24904edeb386a3a2299ae 324 Gene3D G3DSA:2.40.70.10 59 187 9.6E-15 T 29-03-2018 IPR021109 Aspartic peptidase domain GBCGDNIH2_RS01680 12e6908998c24904edeb386a3a2299ae 324 Pfam PF13650 Aspartyl protease 210 299 2.6E-8 T 29-03-2018 GBCGDNIH2_RS01680 12e6908998c24904edeb386a3a2299ae 324 ProSitePatterns PS00141 Eukaryotic and viral aspartyl proteases active site. 76 87 - T 29-03-2018 IPR001969 Aspartic peptidase, active site GO:0004190|GO:0006508 GBCGDNIH2_RS01680 12e6908998c24904edeb386a3a2299ae 324 SUPERFAMILY SSF50630 57 168 1.64E-15 T 29-03-2018 IPR021109 Aspartic peptidase domain GBCGDNIH2_RS01680 12e6908998c24904edeb386a3a2299ae 324 SUPERFAMILY SSF50630 203 309 2.89E-8 T 29-03-2018 IPR021109 Aspartic peptidase domain GBCGDNIH2_RS01680 12e6908998c24904edeb386a3a2299ae 324 Pfam PF13975 gag-polyprotein putative aspartyl protease 65 162 8.4E-14 T 29-03-2018 GBCGDNIH2_RS01680 12e6908998c24904edeb386a3a2299ae 324 ProSitePatterns PS00141 Eukaryotic and viral aspartyl proteases active site. 220 231 - T 29-03-2018 IPR001969 Aspartic peptidase, active site GO:0004190|GO:0006508 GBCGDNIH2_RS03575 8cad00dc6e38beea1f6885dd5313eecc 211 SMART SM00474 6 177 4.9E-30 T 29-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 GBCGDNIH2_RS03575 8cad00dc6e38beea1f6885dd5313eecc 211 Gene3D G3DSA:3.30.420.10 7 198 2.1E-44 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 GBCGDNIH2_RS03575 8cad00dc6e38beea1f6885dd5313eecc 211 SUPERFAMILY SSF53098 21 199 3.8E-52 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 GBCGDNIH2_RS03575 8cad00dc6e38beea1f6885dd5313eecc 211 Pfam PF01612 3'-5' exonuclease 20 174 7.6E-34 T 29-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 GBCGDNIH2_RS10365 104e31e445e409e84776af08227bd6b5 347 Gene3D G3DSA:3.40.50.2000 127 324 6.1E-45 T 29-03-2018 GBCGDNIH2_RS10365 104e31e445e409e84776af08227bd6b5 347 Pfam PF00534 Glycosyl transferases group 1 159 318 1.7E-31 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 GBCGDNIH2_RS10365 104e31e445e409e84776af08227bd6b5 347 SUPERFAMILY SSF53756 2 337 7.63E-65 T 29-03-2018 GBCGDNIH2_RS03545 fdc0b2e438d4206dfd825fdaa0097939 202 Gene3D G3DSA:3.30.160.100 1 101 1.1E-18 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 GBCGDNIH2_RS03545 fdc0b2e438d4206dfd825fdaa0097939 202 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 100 1.0E-14 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 GBCGDNIH2_RS03545 fdc0b2e438d4206dfd825fdaa0097939 202 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 139 191 1.3E-15 T 29-03-2018 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal GBCGDNIH2_RS03545 fdc0b2e438d4206dfd825fdaa0097939 202 SUPERFAMILY SSF69754 1 100 2.22E-21 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 GBCGDNIH2_RS03545 fdc0b2e438d4206dfd825fdaa0097939 202 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 94 2.7E-17 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 GBCGDNIH2_RS03545 fdc0b2e438d4206dfd825fdaa0097939 202 Hamap MF_00839 Ribosome hibernation promoting factor [hpf]. 1 196 19.617 T 29-03-2018 IPR034694 Ribosome hibernation promoting factor, long/plastid GBCGDNIH2_RS00030 e4c6d1e27077c4862da70b5cf619b4d5 186 Pfam PF04390 Lipopolysaccharide-assembly 42 164 6.9E-6 T 29-03-2018 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 GBCGDNIH2_RS11935 0274721141b0603ee769926c97e41b55 220 TIGRFAM TIGR04508 queE_Cx14CxxC: 7-carboxy-7-deazaguanine synthase 13 220 4.4E-107 T 29-03-2018 IPR030977 7-carboxy-7-deazaguanine synthase, Cx14CxxC-type GO:0008616|GO:0046872 KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 GBCGDNIH2_RS11935 0274721141b0603ee769926c97e41b55 220 Pfam PF13394 4Fe-4S single cluster domain 35 130 2.2E-6 T 29-03-2018 GBCGDNIH2_RS11935 0274721141b0603ee769926c97e41b55 220 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 13 220 31.581 T 29-03-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 GBCGDNIH2_RS11935 0274721141b0603ee769926c97e41b55 220 SUPERFAMILY SSF102114 56 149 7.65E-9 T 29-03-2018 GBCGDNIH2_RS11935 0274721141b0603ee769926c97e41b55 220 Pfam PF04055 Radical SAM superfamily 55 150 1.4E-7 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 GBCGDNIH2_RS11935 0274721141b0603ee769926c97e41b55 220 Gene3D G3DSA:3.20.20.70 35 217 6.7E-14 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS11935 0274721141b0603ee769926c97e41b55 220 PIRSF PIRSF000370 11 220 6.8E-37 T 29-03-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 GBCGDNIH2_RS01180 4fa90283a6d2fdd4aeaed1a94b8bc879 304 SUPERFAMILY SSF47240 44 229 1.93E-23 T 29-03-2018 IPR009078 Ferritin-like superfamily GBCGDNIH2_RS01180 4fa90283a6d2fdd4aeaed1a94b8bc879 304 Gene3D G3DSA:1.10.620.20 7 232 4.8E-13 T 29-03-2018 GBCGDNIH2_RS12325 0f1a157bceaf12df6c14ca07d9989e1f 441 Gene3D G3DSA:3.50.50.60 13 202 6.8E-14 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS12325 0f1a157bceaf12df6c14ca07d9989e1f 441 SUPERFAMILY SSF51905 14 240 4.41E-22 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS12325 0f1a157bceaf12df6c14ca07d9989e1f 441 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 14 339 2.7E-105 T 29-03-2018 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase GBCGDNIH2_RS12325 0f1a157bceaf12df6c14ca07d9989e1f 441 Gene3D G3DSA:3.50.50.60 203 415 2.0E-10 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS12325 0f1a157bceaf12df6c14ca07d9989e1f 441 SUPERFAMILY SSF51905 186 374 9.07E-9 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS08135 7369b5e7b789615229892083c58b8be1 946 Gene3D G3DSA:3.40.50.2000 145 308 7.7E-25 T 29-03-2018 GBCGDNIH2_RS08135 7369b5e7b789615229892083c58b8be1 946 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 128 255 1.3E-13 T 29-03-2018 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 GBCGDNIH2_RS08135 7369b5e7b789615229892083c58b8be1 946 Gene3D G3DSA:3.40.50.2000 1 99 2.5E-13 T 29-03-2018 GBCGDNIH2_RS08135 7369b5e7b789615229892083c58b8be1 946 Pfam PF14307 Glycosyltransferase WbsX 457 795 4.0E-118 T 29-03-2018 IPR032719 Glycosyltransferase WbsX GBCGDNIH2_RS08135 7369b5e7b789615229892083c58b8be1 946 SUPERFAMILY SSF53756 9 299 4.39E-43 T 29-03-2018 GBCGDNIH2_RS02730 52036365b09ce02b8117d8e583b56515 342 PRINTS PR00069 Aldo-keto reductase signature 112 130 3.4E-5 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 GBCGDNIH2_RS02730 52036365b09ce02b8117d8e583b56515 342 PRINTS PR00069 Aldo-keto reductase signature 143 160 3.4E-5 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 GBCGDNIH2_RS02730 52036365b09ce02b8117d8e583b56515 342 Gene3D G3DSA:3.20.20.100 1 333 1.2E-86 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain GBCGDNIH2_RS02730 52036365b09ce02b8117d8e583b56515 342 SUPERFAMILY SSF51430 2 318 1.31E-94 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain GBCGDNIH2_RS02730 52036365b09ce02b8117d8e583b56515 342 Pfam PF00248 Aldo/keto reductase family 16 318 3.4E-66 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain GBCGDNIH2_RS04210 03e1f99f9a2ceeb85ee8b833d7f893b4 346 SUPERFAMILY SSF52418 82 343 2.75E-88 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 GBCGDNIH2_RS04210 03e1f99f9a2ceeb85ee8b833d7f893b4 346 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 17 338 4.9E-110 T 29-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 GBCGDNIH2_RS04210 03e1f99f9a2ceeb85ee8b833d7f893b4 346 SUPERFAMILY SSF47648 14 78 4.84E-18 T 29-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 GBCGDNIH2_RS04210 03e1f99f9a2ceeb85ee8b833d7f893b4 346 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 14 341 36.963 T 29-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 GBCGDNIH2_RS04210 03e1f99f9a2ceeb85ee8b833d7f893b4 346 Pfam PF02885 Glycosyl transferase family, helical bundle domain 15 74 2.4E-17 T 29-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 GBCGDNIH2_RS04210 03e1f99f9a2ceeb85ee8b833d7f893b4 346 Gene3D G3DSA:3.40.1030.10 79 346 3.6E-100 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 GBCGDNIH2_RS04210 03e1f99f9a2ceeb85ee8b833d7f893b4 346 Pfam PF00591 Glycosyl transferase family, a/b domain 84 332 1.7E-88 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 GBCGDNIH2_RS04210 03e1f99f9a2ceeb85ee8b833d7f893b4 346 Gene3D G3DSA:1.20.970.10 8 78 1.2E-21 T 29-03-2018 GBCGDNIH2_RS06505 9a477c7490a37dc1f17bec5d6378f840 296 PRINTS PR00691 Adhesin B signature 69 88 7.9E-25 T 29-03-2018 IPR006129 Adhesin B GO:0007155 GBCGDNIH2_RS06505 9a477c7490a37dc1f17bec5d6378f840 296 PRINTS PR00691 Adhesin B signature 229 246 7.9E-25 T 29-03-2018 IPR006129 Adhesin B GO:0007155 GBCGDNIH2_RS06505 9a477c7490a37dc1f17bec5d6378f840 296 PRINTS PR00691 Adhesin B signature 50 68 7.9E-25 T 29-03-2018 IPR006129 Adhesin B GO:0007155 GBCGDNIH2_RS06505 9a477c7490a37dc1f17bec5d6378f840 296 PRINTS PR00691 Adhesin B signature 272 290 7.9E-25 T 29-03-2018 IPR006129 Adhesin B GO:0007155 GBCGDNIH2_RS06505 9a477c7490a37dc1f17bec5d6378f840 296 PRINTS PR00691 Adhesin B signature 180 197 7.9E-25 T 29-03-2018 IPR006129 Adhesin B GO:0007155 GBCGDNIH2_RS06505 9a477c7490a37dc1f17bec5d6378f840 296 PRINTS PR00691 Adhesin B signature 25 46 7.9E-25 T 29-03-2018 IPR006129 Adhesin B GO:0007155 GBCGDNIH2_RS06505 9a477c7490a37dc1f17bec5d6378f840 296 SUPERFAMILY SSF53807 21 293 2.21E-82 T 29-03-2018 GBCGDNIH2_RS06505 9a477c7490a37dc1f17bec5d6378f840 296 Gene3D G3DSA:3.40.50.1980 15 172 4.1E-49 T 29-03-2018 GBCGDNIH2_RS06505 9a477c7490a37dc1f17bec5d6378f840 296 Pfam PF01297 Zinc-uptake complex component A periplasmic 28 289 1.2E-75 T 29-03-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 GBCGDNIH2_RS06505 9a477c7490a37dc1f17bec5d6378f840 296 Gene3D G3DSA:3.40.50.1980 173 294 1.4E-31 T 29-03-2018 GBCGDNIH2_RS06505 9a477c7490a37dc1f17bec5d6378f840 296 PRINTS PR00690 Adhesin family signature 56 69 2.1E-31 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 GBCGDNIH2_RS06505 9a477c7490a37dc1f17bec5d6378f840 296 PRINTS PR00690 Adhesin family signature 25 43 2.1E-31 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 GBCGDNIH2_RS06505 9a477c7490a37dc1f17bec5d6378f840 296 PRINTS PR00690 Adhesin family signature 180 201 2.1E-31 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 GBCGDNIH2_RS06505 9a477c7490a37dc1f17bec5d6378f840 296 PRINTS PR00690 Adhesin family signature 69 86 2.1E-31 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 GBCGDNIH2_RS06505 9a477c7490a37dc1f17bec5d6378f840 296 PRINTS PR00690 Adhesin family signature 233 251 2.1E-31 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 GBCGDNIH2_RS06505 9a477c7490a37dc1f17bec5d6378f840 296 PRINTS PR00690 Adhesin family signature 259 278 2.1E-31 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 GBCGDNIH2_RS03640 6432b34463b6c337a2417c00f5564f3e 312 Gene3D G3DSA:1.10.760.10 191 303 7.9E-18 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 GBCGDNIH2_RS03640 6432b34463b6c337a2417c00f5564f3e 312 SUPERFAMILY SSF46626 193 289 3.06E-25 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 GBCGDNIH2_RS03640 6432b34463b6c337a2417c00f5564f3e 312 Gene3D G3DSA:2.60.370.10 54 180 4.5E-53 T 29-03-2018 IPR023471 Cytochrome c oxidase assembly protein CtaG/Cox11, domain Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS03640 6432b34463b6c337a2417c00f5564f3e 312 Hamap MF_00155 Cytochrome c oxidase assembly protein CtaG [ctaG]. 1 181 35.018 T 29-03-2018 IPR007533 Cytochrome c oxidase assembly protein CtaG/Cox11 GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS03640 6432b34463b6c337a2417c00f5564f3e 312 SUPERFAMILY SSF110111 53 178 3.66E-49 T 29-03-2018 IPR023471 Cytochrome c oxidase assembly protein CtaG/Cox11, domain Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS03640 6432b34463b6c337a2417c00f5564f3e 312 Pfam PF00034 Cytochrome c 195 289 2.5E-7 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 GBCGDNIH2_RS03640 6432b34463b6c337a2417c00f5564f3e 312 PRINTS PR00604 Class IA and IB cytochrome C signature 205 212 2.2E-11 T 29-03-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS03640 6432b34463b6c337a2417c00f5564f3e 312 PRINTS PR00604 Class IA and IB cytochrome C signature 245 261 2.2E-11 T 29-03-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS03640 6432b34463b6c337a2417c00f5564f3e 312 PRINTS PR00604 Class IA and IB cytochrome C signature 280 288 2.2E-11 T 29-03-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS03640 6432b34463b6c337a2417c00f5564f3e 312 PRINTS PR00604 Class IA and IB cytochrome C signature 215 230 2.2E-11 T 29-03-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS03640 6432b34463b6c337a2417c00f5564f3e 312 PRINTS PR00604 Class IA and IB cytochrome C signature 231 241 2.2E-11 T 29-03-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS03640 6432b34463b6c337a2417c00f5564f3e 312 Pfam PF04442 Cytochrome c oxidase assembly protein CtaG/Cox11 29 175 2.8E-57 T 29-03-2018 IPR007533 Cytochrome c oxidase assembly protein CtaG/Cox11 GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS03375 a2f55e9194ee668ad2407f10103325c1 262 Pfam PF02571 Precorrin-6x reductase CbiJ/CobK 10 249 8.2E-66 T 29-03-2018 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 GBCGDNIH2_RS03375 a2f55e9194ee668ad2407f10103325c1 262 Gene3D G3DSA:3.40.50.2300 72 261 5.1E-16 T 29-03-2018 GBCGDNIH2_RS00520 89e8c70682434ddef0ab08a015f42b8a 291 Gene3D G3DSA:3.90.550.10 3 291 6.5E-67 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS00520 89e8c70682434ddef0ab08a015f42b8a 291 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 3 287 2.1E-138 T 29-03-2018 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|KEGG: 00525+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 GBCGDNIH2_RS00520 89e8c70682434ddef0ab08a015f42b8a 291 Pfam PF00483 Nucleotidyl transferase 3 239 3.7E-66 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 GBCGDNIH2_RS00520 89e8c70682434ddef0ab08a015f42b8a 291 SUPERFAMILY SSF53448 3 286 3.11E-82 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS04315 e55c38cedbf205137dcaa769f482018f 203 Gene3D G3DSA:3.40.30.10 24 198 2.0E-27 T 29-03-2018 GBCGDNIH2_RS04315 e55c38cedbf205137dcaa769f482018f 203 SUPERFAMILY SSF52833 33 189 1.76E-34 T 29-03-2018 IPR012336 Thioredoxin-like fold GBCGDNIH2_RS04315 e55c38cedbf205137dcaa769f482018f 203 Pfam PF00578 AhpC/TSA family 36 157 2.6E-24 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 GBCGDNIH2_RS12125 873c6f24e9b39804b1fcb5aee0d5c090 156 Pfam PF12100 Domain of unknown function (DUF3576) 51 149 7.0E-42 T 29-03-2018 IPR021959 Protein of unknown function DUF3576 GBCGDNIH2_RS07660 8eb0ec21924b30ba5106056a4a7714f9 430 Gene3D G3DSA:3.40.710.10 124 430 1.3E-42 T 29-03-2018 GBCGDNIH2_RS07660 8eb0ec21924b30ba5106056a4a7714f9 430 Pfam PF00144 Beta-lactamase 141 424 1.5E-26 T 29-03-2018 IPR001466 Beta-lactamase-related GBCGDNIH2_RS07660 8eb0ec21924b30ba5106056a4a7714f9 430 SUPERFAMILY SSF56601 90 414 1.41E-67 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like GBCGDNIH2_RS01410 cb78a819dfd2bc96fde5ab9d8da34b84 107 Hamap MF_00634 UPF0235 protein YggU [yggU]. 7 99 17.368 T 29-03-2018 IPR003746 Protein of unknown function DUF167 GBCGDNIH2_RS01410 cb78a819dfd2bc96fde5ab9d8da34b84 107 Pfam PF02594 Uncharacterised ACR, YggU family COG1872 10 87 1.2E-21 T 29-03-2018 IPR003746 Protein of unknown function DUF167 GBCGDNIH2_RS01410 cb78a819dfd2bc96fde5ab9d8da34b84 107 SUPERFAMILY SSF69786 2 100 4.19E-20 T 29-03-2018 IPR003746 Protein of unknown function DUF167 GBCGDNIH2_RS01410 cb78a819dfd2bc96fde5ab9d8da34b84 107 SMART SM01152 7 88 9.7E-28 T 29-03-2018 IPR003746 Protein of unknown function DUF167 GBCGDNIH2_RS01410 cb78a819dfd2bc96fde5ab9d8da34b84 107 Gene3D G3DSA:3.30.1200.10 1 106 3.6E-24 T 29-03-2018 IPR003746 Protein of unknown function DUF167 GBCGDNIH2_RS00015 391c973bf72885998474e7f37d42fc4b 283 Hamap MF_00921 Putative pyruvate, phosphate dikinase regulatory protein. 6 271 56.679 T 29-03-2018 IPR026565 Putative pyruvate, phosphate dikinase regulatory protein GBCGDNIH2_RS00015 391c973bf72885998474e7f37d42fc4b 283 Pfam PF03618 Kinase/pyrophosphorylase 8 266 3.8E-86 T 29-03-2018 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 GBCGDNIH2_RS00015 391c973bf72885998474e7f37d42fc4b 283 Gene3D G3DSA:3.40.50.300 2 279 1.6E-10 T 29-03-2018 GBCGDNIH2_RS07335 a26edeab5757fa08512420c83382bf36 95 Pfam PF09707 CRISPR-associated protein (Cas_Cas2CT1978) 1 86 1.9E-36 T 29-03-2018 IPR010152 CRISPR-associated protein Cas2 subtype GBCGDNIH2_RS07335 a26edeab5757fa08512420c83382bf36 95 TIGRFAM TIGR01873 cas_CT1978: CRISPR-associated endoribonuclease Cas2, subtype I-E/ECOLI 1 86 2.3E-33 T 29-03-2018 IPR010152 CRISPR-associated protein Cas2 subtype GBCGDNIH2_RS10080 d110abd5934dc5f2480eb733d17786d8 227 SUPERFAMILY SSF53335 34 168 7.98E-23 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GBCGDNIH2_RS10080 d110abd5934dc5f2480eb733d17786d8 227 Gene3D G3DSA:3.40.50.150 12 221 8.6E-9 T 29-03-2018 GBCGDNIH2_RS03550 e8a44afb5b3df06b730eaf8d0f0d1ca9 525 Gene3D G3DSA:1.10.10.10 367 454 1.4E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS03550 e8a44afb5b3df06b730eaf8d0f0d1ca9 525 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 499 506 - T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 GBCGDNIH2_RS03550 e8a44afb5b3df06b730eaf8d0f0d1ca9 525 Pfam PF04963 Sigma-54 factor, core binding domain 140 343 1.5E-37 T 29-03-2018 IPR007046 RNA polymerase sigma factor 54, core-binding GO:0003677|GO:0006352 GBCGDNIH2_RS03550 e8a44afb5b3df06b730eaf8d0f0d1ca9 525 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 408 427 - T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 GBCGDNIH2_RS03550 e8a44afb5b3df06b730eaf8d0f0d1ca9 525 Pfam PF04552 Sigma-54, DNA binding domain 361 519 1.0E-69 T 29-03-2018 IPR007634 RNA polymerase sigma factor 54, DNA-binding GBCGDNIH2_RS03550 e8a44afb5b3df06b730eaf8d0f0d1ca9 525 PRINTS PR00045 Sigma-54 factor signature 211 228 3.6E-14 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 GBCGDNIH2_RS03550 e8a44afb5b3df06b730eaf8d0f0d1ca9 525 PRINTS PR00045 Sigma-54 factor signature 494 512 3.6E-14 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 GBCGDNIH2_RS03550 e8a44afb5b3df06b730eaf8d0f0d1ca9 525 PIRSF PIRSF000774 10 319 4.4E-54 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 GBCGDNIH2_RS03550 e8a44afb5b3df06b730eaf8d0f0d1ca9 525 PIRSF PIRSF000774 302 521 5.7E-81 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 GBCGDNIH2_RS03550 e8a44afb5b3df06b730eaf8d0f0d1ca9 525 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 14 58 1.0E-18 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 GBCGDNIH2_RS05315 bbc363ab5ba879c783f974fed0ef29e1 248 Gene3D G3DSA:3.40.30.10 6 238 5.0E-46 T 29-03-2018 GBCGDNIH2_RS05315 bbc363ab5ba879c783f974fed0ef29e1 248 Pfam PF01323 DSBA-like thioredoxin domain 143 235 7.2E-17 T 29-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 GBCGDNIH2_RS05315 bbc363ab5ba879c783f974fed0ef29e1 248 Pfam PF01323 DSBA-like thioredoxin domain 11 120 2.9E-18 T 29-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 GBCGDNIH2_RS05315 bbc363ab5ba879c783f974fed0ef29e1 248 SUPERFAMILY SSF52833 11 237 1.04E-34 T 29-03-2018 IPR012336 Thioredoxin-like fold GBCGDNIH2_RS02780 3d79f732fa2cf8776a18d8ca44f624b8 1898 Gene3D G3DSA:2.150.10.10 1370 1663 1.9E-4 T 29-03-2018 GBCGDNIH2_RS02780 3d79f732fa2cf8776a18d8ca44f624b8 1898 Gene3D G3DSA:2.150.10.10 1721 1896 3.0E-10 T 29-03-2018 GBCGDNIH2_RS02780 3d79f732fa2cf8776a18d8ca44f624b8 1898 Pfam PF16168 Adhesin of bacterial autotransporter system, probable stalk 766 813 5.1E-7 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS02780 3d79f732fa2cf8776a18d8ca44f624b8 1898 Pfam PF16168 Adhesin of bacterial autotransporter system, probable stalk 1170 1215 2.8E-7 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS02780 3d79f732fa2cf8776a18d8ca44f624b8 1898 SUPERFAMILY SSF51120 1697 1889 1.96E-12 T 29-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal GBCGDNIH2_RS02780 3d79f732fa2cf8776a18d8ca44f624b8 1898 SUPERFAMILY SSF51120 1522 1721 8.89E-6 T 29-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal GBCGDNIH2_RS02780 3d79f732fa2cf8776a18d8ca44f624b8 1898 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 1174 1210 2.2E-10 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS02780 3d79f732fa2cf8776a18d8ca44f624b8 1898 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 1161 1191 5.9E-7 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS02780 3d79f732fa2cf8776a18d8ca44f624b8 1898 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 1006 1042 2.3E-7 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS02780 3d79f732fa2cf8776a18d8ca44f624b8 1898 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 970 1004 3.2E-5 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS02780 3d79f732fa2cf8776a18d8ca44f624b8 1898 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 144 181 1.6E-7 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS02780 3d79f732fa2cf8776a18d8ca44f624b8 1898 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 377 407 7.6E-6 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS02780 3d79f732fa2cf8776a18d8ca44f624b8 1898 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 749 786 2.3E-8 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS02780 3d79f732fa2cf8776a18d8ca44f624b8 1898 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 790 824 4.7E-9 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS02780 3d79f732fa2cf8776a18d8ca44f624b8 1898 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 466 498 1.7E-8 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS10280 26b6f1126a1919502f55a94b474d2e31 231 Pfam PF02678 Pirin 15 118 3.9E-36 T 29-03-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 GBCGDNIH2_RS10280 26b6f1126a1919502f55a94b474d2e31 231 Gene3D G3DSA:2.60.120.10 11 130 4.8E-45 T 29-03-2018 IPR014710 RmlC-like jelly roll fold GBCGDNIH2_RS10280 26b6f1126a1919502f55a94b474d2e31 231 SUPERFAMILY SSF51182 1 230 1.78E-71 T 29-03-2018 IPR011051 RmlC-like cupin domain GBCGDNIH2_RS10280 26b6f1126a1919502f55a94b474d2e31 231 PIRSF PIRSF006232 3 231 2.7E-51 T 29-03-2018 IPR012093 Pirin Reactome: R-HSA-8935690 GBCGDNIH2_RS10280 26b6f1126a1919502f55a94b474d2e31 231 Gene3D G3DSA:2.60.120.10 131 231 7.1E-19 T 29-03-2018 IPR014710 RmlC-like jelly roll fold GBCGDNIH2_RS01890 36a1a2340a3b0759b7311ab92fc7546e 103 Gene3D G3DSA:1.10.3340.10 6 88 2.8E-41 T 29-03-2018 IPR023163 SMc04008-like domain GBCGDNIH2_RS01890 36a1a2340a3b0759b7311ab92fc7546e 103 SUPERFAMILY SSF158757 5 81 5.75E-37 T 29-03-2018 IPR023163 SMc04008-like domain GBCGDNIH2_RS01890 36a1a2340a3b0759b7311ab92fc7546e 103 Pfam PF06844 Protein of unknown function (DUF1244) 32 98 3.8E-36 T 29-03-2018 IPR023163 SMc04008-like domain GBCGDNIH2_RS09770 042d72c3f8ab211ce763b4f9ce066d0a 251 PRINTS PR00123 ATP synthase A subunit signature 150 165 1.6E-29 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 GBCGDNIH2_RS09770 042d72c3f8ab211ce763b4f9ce066d0a 251 PRINTS PR00123 ATP synthase A subunit signature 170 192 1.6E-29 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 GBCGDNIH2_RS09770 042d72c3f8ab211ce763b4f9ce066d0a 251 PRINTS PR00123 ATP synthase A subunit signature 89 105 1.6E-29 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 GBCGDNIH2_RS09770 042d72c3f8ab211ce763b4f9ce066d0a 251 PRINTS PR00123 ATP synthase A subunit signature 231 246 1.6E-29 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 GBCGDNIH2_RS09770 042d72c3f8ab211ce763b4f9ce066d0a 251 Pfam PF00119 ATP synthase A chain 35 244 2.8E-58 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 GBCGDNIH2_RS09770 042d72c3f8ab211ce763b4f9ce066d0a 251 Gene3D G3DSA:1.20.120.220 51 251 1.5E-45 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 GBCGDNIH2_RS09770 042d72c3f8ab211ce763b4f9ce066d0a 251 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 12 247 2.9E-64 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 GBCGDNIH2_RS09770 042d72c3f8ab211ce763b4f9ce066d0a 251 ProSitePatterns PS00449 ATP synthase a subunit signature. 173 182 - T 29-03-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 GBCGDNIH2_RS09770 042d72c3f8ab211ce763b4f9ce066d0a 251 SUPERFAMILY SSF81336 80 244 4.84E-46 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 GBCGDNIH2_RS09770 042d72c3f8ab211ce763b4f9ce066d0a 251 Hamap MF_01393 ATP synthase subunit a [atpB]. 11 251 16.114 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 GBCGDNIH2_RS00125 2b8b824a54aac00cd1d0d8a4559821d8 250 Pfam PF01138 3' exoribonuclease family, domain 1 19 146 1.8E-21 T 29-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 GBCGDNIH2_RS00125 2b8b824a54aac00cd1d0d8a4559821d8 250 ProSitePatterns PS01277 Ribonuclease PH signature. 124 136 - T 29-03-2018 IPR018336 Ribonuclease PH, conserved site GBCGDNIH2_RS00125 2b8b824a54aac00cd1d0d8a4559821d8 250 Hamap MF_00564 Ribonuclease PH [rph]. 9 245 46.193 T 29-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 GBCGDNIH2_RS00125 2b8b824a54aac00cd1d0d8a4559821d8 250 Pfam PF03725 3' exoribonuclease family, domain 2 167 231 2.7E-8 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 GBCGDNIH2_RS00125 2b8b824a54aac00cd1d0d8a4559821d8 250 SUPERFAMILY SSF54211 8 189 1.67E-44 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold GBCGDNIH2_RS00125 2b8b824a54aac00cd1d0d8a4559821d8 250 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 10 244 2.2E-105 T 29-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 GBCGDNIH2_RS00125 2b8b824a54aac00cd1d0d8a4559821d8 250 SUPERFAMILY SSF55666 161 244 8.9E-23 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 GBCGDNIH2_RS00125 2b8b824a54aac00cd1d0d8a4559821d8 250 Gene3D G3DSA:3.30.230.70 5 250 6.2E-56 T 29-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 GBCGDNIH2_RS07135 e517fbeedf7b3fddcc642e7c4a5bce45 796 Pfam PF00577 Outer membrane usher protein 210 698 4.8E-39 T 29-03-2018 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS00985 25e3bf341fccdd844f05358a35a9025b 652 SUPERFAMILY SSF81901 153 357 7.85E-40 T 29-03-2018 GBCGDNIH2_RS00985 25e3bf341fccdd844f05358a35a9025b 652 SMART SM00671 276 311 9.3E-5 T 29-03-2018 IPR006597 Sel1-like repeat GBCGDNIH2_RS00985 25e3bf341fccdd844f05358a35a9025b 652 SMART SM00671 491 526 0.023 T 29-03-2018 IPR006597 Sel1-like repeat GBCGDNIH2_RS00985 25e3bf341fccdd844f05358a35a9025b 652 SMART SM00671 312 347 9.3E-7 T 29-03-2018 IPR006597 Sel1-like repeat GBCGDNIH2_RS00985 25e3bf341fccdd844f05358a35a9025b 652 SMART SM00671 563 598 0.0079 T 29-03-2018 IPR006597 Sel1-like repeat GBCGDNIH2_RS00985 25e3bf341fccdd844f05358a35a9025b 652 SMART SM00671 240 275 4.5E-4 T 29-03-2018 IPR006597 Sel1-like repeat GBCGDNIH2_RS00985 25e3bf341fccdd844f05358a35a9025b 652 SMART SM00671 168 203 0.003 T 29-03-2018 IPR006597 Sel1-like repeat GBCGDNIH2_RS00985 25e3bf341fccdd844f05358a35a9025b 652 SMART SM00671 131 167 89.0 T 29-03-2018 IPR006597 Sel1-like repeat GBCGDNIH2_RS00985 25e3bf341fccdd844f05358a35a9025b 652 SMART SM00671 527 562 1.6E-4 T 29-03-2018 IPR006597 Sel1-like repeat GBCGDNIH2_RS00985 25e3bf341fccdd844f05358a35a9025b 652 SMART SM00671 420 454 0.045 T 29-03-2018 IPR006597 Sel1-like repeat GBCGDNIH2_RS00985 25e3bf341fccdd844f05358a35a9025b 652 SMART SM00671 46 81 7.8E-6 T 29-03-2018 IPR006597 Sel1-like repeat GBCGDNIH2_RS00985 25e3bf341fccdd844f05358a35a9025b 652 SMART SM00671 348 383 7.5E-5 T 29-03-2018 IPR006597 Sel1-like repeat GBCGDNIH2_RS00985 25e3bf341fccdd844f05358a35a9025b 652 SMART SM00671 455 490 0.0052 T 29-03-2018 IPR006597 Sel1-like repeat GBCGDNIH2_RS00985 25e3bf341fccdd844f05358a35a9025b 652 SUPERFAMILY SSF81901 409 604 9.59E-39 T 29-03-2018 GBCGDNIH2_RS00985 25e3bf341fccdd844f05358a35a9025b 652 Pfam PF08238 Sel1 repeat 241 274 0.014 T 29-03-2018 IPR006597 Sel1-like repeat GBCGDNIH2_RS00985 25e3bf341fccdd844f05358a35a9025b 652 Pfam PF08238 Sel1 repeat 422 452 6.4E-4 T 29-03-2018 IPR006597 Sel1-like repeat GBCGDNIH2_RS00985 25e3bf341fccdd844f05358a35a9025b 652 Pfam PF08238 Sel1 repeat 133 167 0.071 T 29-03-2018 IPR006597 Sel1-like repeat GBCGDNIH2_RS00985 25e3bf341fccdd844f05358a35a9025b 652 Pfam PF08238 Sel1 repeat 169 202 8.8E-4 T 29-03-2018 IPR006597 Sel1-like repeat GBCGDNIH2_RS00985 25e3bf341fccdd844f05358a35a9025b 652 Pfam PF08238 Sel1 repeat 563 597 8.6E-4 T 29-03-2018 IPR006597 Sel1-like repeat GBCGDNIH2_RS00985 25e3bf341fccdd844f05358a35a9025b 652 Pfam PF08238 Sel1 repeat 457 487 9.4E-4 T 29-03-2018 IPR006597 Sel1-like repeat GBCGDNIH2_RS00985 25e3bf341fccdd844f05358a35a9025b 652 Pfam PF08238 Sel1 repeat 502 526 0.72 T 29-03-2018 IPR006597 Sel1-like repeat GBCGDNIH2_RS00985 25e3bf341fccdd844f05358a35a9025b 652 Pfam PF08238 Sel1 repeat 277 311 4.1E-6 T 29-03-2018 IPR006597 Sel1-like repeat GBCGDNIH2_RS00985 25e3bf341fccdd844f05358a35a9025b 652 Pfam PF08238 Sel1 repeat 529 562 3.1E-6 T 29-03-2018 IPR006597 Sel1-like repeat GBCGDNIH2_RS00985 25e3bf341fccdd844f05358a35a9025b 652 Pfam PF08238 Sel1 repeat 46 80 1.6E-6 T 29-03-2018 IPR006597 Sel1-like repeat GBCGDNIH2_RS00985 25e3bf341fccdd844f05358a35a9025b 652 Pfam PF08238 Sel1 repeat 350 383 2.7E-5 T 29-03-2018 IPR006597 Sel1-like repeat GBCGDNIH2_RS00985 25e3bf341fccdd844f05358a35a9025b 652 Pfam PF08238 Sel1 repeat 83 110 11.0 T 29-03-2018 IPR006597 Sel1-like repeat GBCGDNIH2_RS00985 25e3bf341fccdd844f05358a35a9025b 652 Pfam PF08238 Sel1 repeat 312 347 2.3E-5 T 29-03-2018 IPR006597 Sel1-like repeat GBCGDNIH2_RS00985 25e3bf341fccdd844f05358a35a9025b 652 SUPERFAMILY SSF81901 24 105 3.92E-14 T 29-03-2018 GBCGDNIH2_RS00985 25e3bf341fccdd844f05358a35a9025b 652 Gene3D G3DSA:2.60.40.1180 23 133 2.5E-14 T 29-03-2018 GBCGDNIH2_RS00985 25e3bf341fccdd844f05358a35a9025b 652 Gene3D G3DSA:2.60.40.1180 403 488 1.1E-15 T 29-03-2018 GBCGDNIH2_RS00985 25e3bf341fccdd844f05358a35a9025b 652 Gene3D G3DSA:2.60.40.1180 306 402 3.8E-19 T 29-03-2018 GBCGDNIH2_RS00985 25e3bf341fccdd844f05358a35a9025b 652 Gene3D G3DSA:2.60.40.1180 509 609 5.5E-18 T 29-03-2018 GBCGDNIH2_RS00985 25e3bf341fccdd844f05358a35a9025b 652 Gene3D G3DSA:2.60.40.1180 230 305 3.3E-13 T 29-03-2018 GBCGDNIH2_RS00985 25e3bf341fccdd844f05358a35a9025b 652 Gene3D G3DSA:2.60.40.1180 134 191 5.6E-6 T 29-03-2018 GBCGDNIH2_RS00985 25e3bf341fccdd844f05358a35a9025b 652 Gene3D G3DSA:2.60.40.1180 192 229 0.0019 T 29-03-2018 GBCGDNIH2_RS09785 a9586018c1a91fef5b7e731c8df25ad1 171 Pfam PF00430 ATP synthase B/B' CF(0) 16 144 1.2E-22 T 29-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 GBCGDNIH2_RS09785 a9586018c1a91fef5b7e731c8df25ad1 171 Hamap MF_01398 ATP synthase subunit b [atpF]. 4 146 11.147 T 29-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 GBCGDNIH2_RS08665 720915b160de331dae5325f5b9baee4a 723 SUPERFAMILY SSF51294 379 515 1.27E-8 T 29-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 GBCGDNIH2_RS08665 720915b160de331dae5325f5b9baee4a 723 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 30 67 2.4E-5 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system GBCGDNIH2_RS08665 720915b160de331dae5325f5b9baee4a 723 Pfam PF13403 Hint domain 378 517 7.7E-37 T 29-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 GBCGDNIH2_RS08665 720915b160de331dae5325f5b9baee4a 723 Gene3D G3DSA:2.170.16.10 374 547 4.1E-18 T 29-03-2018 GBCGDNIH2_RS11410 82b35afa5b8562dd55413192bcedbacd 389 TIGRFAM TIGR04407 LptF_YjgP: LPS export ABC transporter permease LptF 10 363 2.5E-79 T 29-03-2018 IPR030922 LPS export ABC transporter permease LptF GO:0043190|GO:0055085 GBCGDNIH2_RS11410 82b35afa5b8562dd55413192bcedbacd 389 Pfam PF03739 Predicted permease YjgP/YjgQ family 12 361 2.1E-70 T 29-03-2018 IPR005495 Permease LptG/LptF-related GO:0016021 GBCGDNIH2_RS11785 942c5b0404bf275423cc10425e09f2e5 196 Gene3D G3DSA:1.10.10.10 82 123 7.3E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS11785 942c5b0404bf275423cc10425e09f2e5 196 Pfam PF02631 RecX family 64 180 5.5E-19 T 29-03-2018 IPR003783 Regulatory protein RecX GO:0006282 GBCGDNIH2_RS11785 942c5b0404bf275423cc10425e09f2e5 196 Gene3D G3DSA:1.10.10.10 9 79 0.011 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS00400 422bccd462b25b73a4c7b62befc2176c 182 Gene3D G3DSA:3.30.70.1520 29 91 6.2E-14 T 29-03-2018 GBCGDNIH2_RS00400 422bccd462b25b73a4c7b62befc2176c 182 Pfam PF04268 Sarcosine oxidase, gamma subunit family 43 179 9.4E-33 T 29-03-2018 IPR007375 Sarcosine oxidase, gamma subunit KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 GBCGDNIH2_RS00400 422bccd462b25b73a4c7b62befc2176c 182 Gene3D G3DSA:3.30.1360.120 92 182 1.0E-4 T 29-03-2018 GBCGDNIH2_RS00400 422bccd462b25b73a4c7b62befc2176c 182 SUPERFAMILY SSF103025 67 180 3.53E-9 T 29-03-2018 GBCGDNIH2_RS11805 b9615486aa28f44530259273e2d11dfd 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 GBCGDNIH2_RS11805 b9615486aa28f44530259273e2d11dfd 247 Pfam PF00106 short chain dehydrogenase 5 194 5.0E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS11805 b9615486aa28f44530259273e2d11dfd 247 SUPERFAMILY SSF51735 4 244 1.72E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS11805 b9615486aa28f44530259273e2d11dfd 247 Gene3D G3DSA:3.40.50.720 2 246 5.8E-42 T 29-03-2018 GBCGDNIH2_RS11805 b9615486aa28f44530259273e2d11dfd 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 2.0E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS11805 b9615486aa28f44530259273e2d11dfd 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 2.0E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS11805 b9615486aa28f44530259273e2d11dfd 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 2.0E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS11805 b9615486aa28f44530259273e2d11dfd 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 2.0E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS11805 b9615486aa28f44530259273e2d11dfd 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 2.0E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR GBCGDNIH2_RS01080 ee3dce1fdade7be6cb9a96430ef5191f 343 Pfam PF08904 Domain of unknown function (DUF1849) 104 340 2.3E-69 T 29-03-2018 IPR015000 Protein of unknown function DUF1849 GBCGDNIH2_RS08730 2bc2a882fc19522606c6528a69ba7b8a 230 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 22 197 1.1E-59 T 29-03-2018 IPR022301 Integral membrane protein YjbE GBCGDNIH2_RS08730 2bc2a882fc19522606c6528a69ba7b8a 230 Pfam PF03741 Integral membrane protein TerC family 23 197 2.9E-43 T 29-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 GBCGDNIH2_RS02500 8ed46a0cbc5095a43def031c85a98f19 434 Gene3D G3DSA:3.20.20.60 15 417 1.3E-142 T 29-03-2018 GBCGDNIH2_RS02500 8ed46a0cbc5095a43def031c85a98f19 434 SUPERFAMILY SSF51621 19 433 4.17E-146 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 GBCGDNIH2_RS02500 8ed46a0cbc5095a43def031c85a98f19 434 ProSitePatterns PS00161 Isocitrate lyase signature. 192 197 - T 29-03-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 GBCGDNIH2_RS02500 8ed46a0cbc5095a43def031c85a98f19 434 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 17 256 8.2E-102 T 29-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 GBCGDNIH2_RS02500 8ed46a0cbc5095a43def031c85a98f19 434 PIRSF PIRSF001362 13 434 6.2E-224 T 29-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 GBCGDNIH2_RS02500 8ed46a0cbc5095a43def031c85a98f19 434 Pfam PF00463 Isocitrate lyase family 19 255 5.2E-55 T 29-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 GBCGDNIH2_RS07725 f35e22673539e0326e29c0d4c98b875c 248 Pfam PF00535 Glycosyl transferase family 2 9 175 2.0E-26 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 GBCGDNIH2_RS07725 f35e22673539e0326e29c0d4c98b875c 248 SUPERFAMILY SSF53448 4 237 4.13E-38 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS07725 f35e22673539e0326e29c0d4c98b875c 248 Gene3D G3DSA:3.90.550.10 3 240 1.6E-32 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS04535 a1810fd1c68a958a72b4d42b70241517 118 Pfam PF11625 Protein of unknown function (DUF3253) 17 97 8.7E-26 T 29-03-2018 IPR021660 Protein of unknown function DUF3253 GBCGDNIH2_RS04535 a1810fd1c68a958a72b4d42b70241517 118 SUPERFAMILY SSF46785 15 98 8.16E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS04535 a1810fd1c68a958a72b4d42b70241517 118 Gene3D G3DSA:1.10.10.10 15 99 4.4E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS08900 f0fe0a8e0c634591d175615b20cdd990 521 TIGRFAM TIGR02547 casA_cse1: CRISPR type I-E/ECOLI-associated protein CasA/Cse1 10 496 6.1E-23 T 29-03-2018 IPR013381 CRISPR-associated protein Cse1 GBCGDNIH2_RS01505 0d9cfbd47cbcaea3f992bc901b030326 159 Gene3D G3DSA:3.10.129.10 12 154 1.0E-28 T 29-03-2018 GBCGDNIH2_RS01505 0d9cfbd47cbcaea3f992bc901b030326 159 SUPERFAMILY SSF54637 15 142 1.57E-32 T 29-03-2018 IPR029069 HotDog domain GBCGDNIH2_RS01505 0d9cfbd47cbcaea3f992bc901b030326 159 Pfam PF13279 Thioesterase-like superfamily 24 137 4.8E-12 T 29-03-2018 GBCGDNIH2_RS01540 7e9ea1451460c1f9b8deab5ec6992b1b 261 Gene3D G3DSA:3.40.50.150 9 244 8.7E-37 T 29-03-2018 GBCGDNIH2_RS01540 7e9ea1451460c1f9b8deab5ec6992b1b 261 SUPERFAMILY SSF53335 36 205 2.13E-39 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GBCGDNIH2_RS01540 7e9ea1451460c1f9b8deab5ec6992b1b 261 Pfam PF08241 Methyltransferase domain 58 154 1.3E-24 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 GBCGDNIH2_RS06325 384f03cc050821433008d3becbd52768 145 Pfam PF13673 Acetyltransferase (GNAT) domain 65 126 1.5E-14 T 29-03-2018 IPR000182 GNAT domain GO:0008080 GBCGDNIH2_RS06325 384f03cc050821433008d3becbd52768 145 SUPERFAMILY SSF55729 2 141 1.17E-24 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase GBCGDNIH2_RS06325 384f03cc050821433008d3becbd52768 145 Gene3D G3DSA:3.40.630.30 1 145 1.3E-25 T 29-03-2018 GBCGDNIH2_RS10615 799f29d183ba559d6f4d661a1b856dd8 204 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 71 92 - T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 GBCGDNIH2_RS10615 799f29d183ba559d6f4d661a1b856dd8 204 PIRSF PIRSF000847 25 202 1.0E-34 T 29-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 GBCGDNIH2_RS10615 799f29d183ba559d6f4d661a1b856dd8 204 Pfam PF01066 CDP-alcohol phosphatidyltransferase 30 92 1.3E-13 T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 GBCGDNIH2_RS12120 23ac36c4de23d7f3163a01519f48ac90 217 Pfam PF02581 Thiamine monophosphate synthase 121 212 6.0E-9 T 29-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 GBCGDNIH2_RS12120 23ac36c4de23d7f3163a01519f48ac90 217 Gene3D G3DSA:3.20.20.70 2 214 1.4E-5 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS12120 23ac36c4de23d7f3163a01519f48ac90 217 SUPERFAMILY SSF51391 22 214 3.14E-13 T 29-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 GBCGDNIH2_RS08970 9a32690ec22ba086d3a3e424919b5cad 228 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 22 226 19.457 T 29-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 GBCGDNIH2_RS08970 9a32690ec22ba086d3a3e424919b5cad 228 Pfam PF01467 Cytidylyltransferase-like 26 205 6.0E-17 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 GBCGDNIH2_RS08970 9a32690ec22ba086d3a3e424919b5cad 228 Gene3D G3DSA:3.40.50.620 17 215 6.7E-38 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GBCGDNIH2_RS08970 9a32690ec22ba086d3a3e424919b5cad 228 SUPERFAMILY SSF52374 22 205 6.26E-38 T 29-03-2018 GBCGDNIH2_RS08395 82062c18dd4cf96b027bf639bcc5bd5d 469 Gene3D G3DSA:2.40.160.10 40 456 3.7E-10 T 29-03-2018 GBCGDNIH2_RS08395 82062c18dd4cf96b027bf639bcc5bd5d 469 Pfam PF07642 Putative beta-barrel porin-2, OmpL-like. bbp2 72 442 7.2E-43 T 29-03-2018 IPR011486 Putative beta-barrel porin-2, OmpL-like. bbp2 GBCGDNIH2_RS11090 21c32f1179891a3996d7f5549817d14d 64 Pfam PF07869 Protein of unknown function (DUF1656) 4 59 1.8E-17 T 29-03-2018 IPR012451 Protein of unknown function DUF1656 GBCGDNIH2_RS06355 637d74567a44d0d26054eaeca6050aba 588 SUPERFAMILY SSF52540 410 558 1.21E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS06355 637d74567a44d0d26054eaeca6050aba 588 SUPERFAMILY SSF52540 25 363 1.21E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS06355 637d74567a44d0d26054eaeca6050aba 588 Pfam PF13245 AAA domain 31 219 3.0E-14 T 29-03-2018 GBCGDNIH2_RS06355 637d74567a44d0d26054eaeca6050aba 588 Gene3D G3DSA:3.40.50.300 7 240 1.5E-23 T 29-03-2018 GBCGDNIH2_RS06355 637d74567a44d0d26054eaeca6050aba 588 Gene3D G3DSA:3.40.50.300 241 569 1.1E-19 T 29-03-2018 GBCGDNIH2_RS04770 e53da3c95c9ef3c316e3786b5a30499b 111 Gene3D G3DSA:3.40.1800.10 14 92 1.9E-5 T 29-03-2018 GBCGDNIH2_RS07285 4987a713e358fda031cc9e34d12d1f3d 66 Pfam PF06698 Protein of unknown function (DUF1192) 3 59 1.4E-17 T 29-03-2018 IPR009579 Protein of unknown function DUF1192 GBCGDNIH2_RS12285 933ffaf0f20f27e821ba023f4711fc51 224 Gene3D G3DSA:3.90.550.10 4 219 9.9E-23 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS12285 933ffaf0f20f27e821ba023f4711fc51 224 SUPERFAMILY SSF53448 8 212 1.1E-26 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS12285 933ffaf0f20f27e821ba023f4711fc51 224 Pfam PF12804 MobA-like NTP transferase domain 10 183 3.9E-31 T 29-03-2018 IPR025877 MobA-like NTP transferase GBCGDNIH2_RS12285 933ffaf0f20f27e821ba023f4711fc51 224 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 6 215 25.271 T 29-03-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 GBCGDNIH2_RS12285 933ffaf0f20f27e821ba023f4711fc51 224 TIGRFAM TIGR02665 molyb_mobA: molybdenum cofactor guanylyltransferase 8 212 8.0E-55 T 29-03-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 GBCGDNIH2_RS08185 c146a38d21142ae25b887e11b30fb684 417 SMART SM00833 273 388 3.1E-54 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal GBCGDNIH2_RS08185 c146a38d21142ae25b887e11b30fb684 417 Gene3D G3DSA:3.40.50.300 10 244 6.9E-53 T 29-03-2018 GBCGDNIH2_RS08185 c146a38d21142ae25b887e11b30fb684 417 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 14 225 1.8E-55 T 29-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain GBCGDNIH2_RS08185 c146a38d21142ae25b887e11b30fb684 417 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 273 388 8.2E-30 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal GBCGDNIH2_RS08185 c146a38d21142ae25b887e11b30fb684 417 Gene3D G3DSA:3.30.1220.10 257 389 4.5E-35 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal GBCGDNIH2_RS08185 c146a38d21142ae25b887e11b30fb684 417 SUPERFAMILY SSF52540 9 331 3.29E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS10560 a81f8e83fbd8be81c2c765a3e4e5e625 106 TIGRFAM TIGR02300 FYDLN_acid: TIGR02300 family protein 1 103 1.2E-16 T 29-03-2018 IPR012644 Conserved hypothetical protein CHP02300, FYDLN acid GBCGDNIH2_RS10560 a81f8e83fbd8be81c2c765a3e4e5e625 106 Pfam PF09538 Protein of unknown function (FYDLN_acid) 1 102 7.7E-24 T 29-03-2018 IPR012644 Conserved hypothetical protein CHP02300, FYDLN acid GBCGDNIH2_RS01870 9e979a48bdf6f2ee041ddf7eae62594c 343 Pfam PF04168 A predicted alpha-helical domain with a conserved ER motif. 8 317 3.8E-78 T 29-03-2018 IPR007296 Domain of unknown function DUF403 GBCGDNIH2_RS01615 e1f19ce15b144c4cea65abf3bddebb89 164 Pfam PF09933 Predicted small integral membrane protein (DUF2165) 3 157 2.1E-63 T 29-03-2018 IPR018681 Protein of unknown function DUF2165, transmembrane GBCGDNIH2_RS06150 f39a6d3c331dd949c48abc7da3150fe4 383 SUPERFAMILY SSF53383 19 375 2.35E-88 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase GBCGDNIH2_RS06150 f39a6d3c331dd949c48abc7da3150fe4 383 Gene3D G3DSA:3.90.1150.10 242 382 6.6E-35 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 GBCGDNIH2_RS06150 f39a6d3c331dd949c48abc7da3150fe4 383 Gene3D G3DSA:3.40.640.10 18 241 9.0E-37 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GBCGDNIH2_RS06150 f39a6d3c331dd949c48abc7da3150fe4 383 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 20 372 1.7E-98 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase GBCGDNIH2_RS06150 f39a6d3c331dd949c48abc7da3150fe4 383 PIRSF PIRSF000390 7 378 1.5E-84 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase GBCGDNIH2_RS07235 97810151f57a05f43a5c790b5ad52a08 608 Pfam PF00654 Voltage gated chloride channel 93 432 7.2E-60 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 GBCGDNIH2_RS07235 97810151f57a05f43a5c790b5ad52a08 608 PRINTS PR00762 Chloride channel signature 133 152 4.4E-12 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 GBCGDNIH2_RS07235 97810151f57a05f43a5c790b5ad52a08 608 PRINTS PR00762 Chloride channel signature 184 203 4.4E-12 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 GBCGDNIH2_RS07235 97810151f57a05f43a5c790b5ad52a08 608 PRINTS PR00762 Chloride channel signature 382 398 4.4E-12 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 GBCGDNIH2_RS07235 97810151f57a05f43a5c790b5ad52a08 608 PRINTS PR00762 Chloride channel signature 400 419 4.4E-12 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 GBCGDNIH2_RS07235 97810151f57a05f43a5c790b5ad52a08 608 PRINTS PR00762 Chloride channel signature 347 367 4.4E-12 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 GBCGDNIH2_RS07235 97810151f57a05f43a5c790b5ad52a08 608 Gene3D G3DSA:1.10.3080.10 24 454 4.9E-62 T 29-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 GBCGDNIH2_RS07235 97810151f57a05f43a5c790b5ad52a08 608 SUPERFAMILY SSF54631 463 596 2.33E-9 T 29-03-2018 GBCGDNIH2_RS07235 97810151f57a05f43a5c790b5ad52a08 608 Gene3D G3DSA:3.10.580.10 516 604 1.2E-4 T 29-03-2018 GBCGDNIH2_RS07235 97810151f57a05f43a5c790b5ad52a08 608 SUPERFAMILY SSF81340 23 453 2.35E-82 T 29-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 GBCGDNIH2_RS07235 97810151f57a05f43a5c790b5ad52a08 608 Gene3D G3DSA:3.10.580.10 455 515 0.017 T 29-03-2018 GBCGDNIH2_RS09010 4db4f88c834ac9e8248c3a54080b2a8c 158 Pfam PF04073 Aminoacyl-tRNA editing domain 25 139 3.3E-27 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 GBCGDNIH2_RS09010 4db4f88c834ac9e8248c3a54080b2a8c 158 SUPERFAMILY SSF55826 5 151 4.58E-40 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 GBCGDNIH2_RS09010 4db4f88c834ac9e8248c3a54080b2a8c 158 Gene3D G3DSA:3.90.960.10 2 153 1.1E-37 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 GBCGDNIH2_RS10430 6b2fae1cff6aa42d4a45676f2da954d8 184 Gene3D G3DSA:1.10.3100.10 51 175 1.3E-19 T 29-03-2018 IPR027910 YdiL-like domain GBCGDNIH2_RS10430 6b2fae1cff6aa42d4a45676f2da954d8 184 SMART SM00530 57 112 2.7E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 GBCGDNIH2_RS10430 6b2fae1cff6aa42d4a45676f2da954d8 184 SUPERFAMILY SSF47413 47 119 2.7E-25 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GBCGDNIH2_RS10430 6b2fae1cff6aa42d4a45676f2da954d8 184 Pfam PF01381 Helix-turn-helix 58 112 1.5E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 GBCGDNIH2_RS04285 912e394dd884f8c7628a41ca87a611e2 99 Gene3D G3DSA:1.10.150.250 17 99 1.4E-24 T 29-03-2018 GBCGDNIH2_RS04285 912e394dd884f8c7628a41ca87a611e2 99 SUPERFAMILY SSF109910 18 95 5.23E-21 T 29-03-2018 IPR005631 Flavinator of succinate dehydrogenase GBCGDNIH2_RS04285 912e394dd884f8c7628a41ca87a611e2 99 Pfam PF03937 Flavinator of succinate dehydrogenase 22 91 9.5E-24 T 29-03-2018 IPR005631 Flavinator of succinate dehydrogenase GBCGDNIH2_RS06880 f32e940a8f82099d08af83b7bc63241d 417 Pfam PF12704 MacB-like periplasmic core domain 28 245 1.6E-17 T 29-03-2018 IPR025857 MacB-like periplasmic core domain GBCGDNIH2_RS06880 f32e940a8f82099d08af83b7bc63241d 417 Pfam PF02687 FtsX-like permease family 302 410 2.0E-14 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 GBCGDNIH2_RS06880 f32e940a8f82099d08af83b7bc63241d 417 TIGRFAM TIGR02212 lolCE: lipoprotein releasing system, transmembrane protein, LolC/E family 5 417 2.3E-131 T 29-03-2018 IPR011925 Lipoprotein-releasing system transmembrane protein LolC/E GO:0016021|GO:0042953|GO:0042954 GBCGDNIH2_RS02025 d8d594b2322575123342238381536aea 278 Gene3D G3DSA:3.40.630.30 25 188 7.8E-31 T 29-03-2018 GBCGDNIH2_RS02025 d8d594b2322575123342238381536aea 278 Pfam PF13444 Acetyltransferase (GNAT) domain 42 149 2.3E-33 T 29-03-2018 GBCGDNIH2_RS02025 d8d594b2322575123342238381536aea 278 SUPERFAMILY SSF55729 26 244 1.12E-39 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase GBCGDNIH2_RS00100 1ce09df2bd5b98a2134afe13b37f87c8 262 Gene3D G3DSA:3.40.50.300 20 261 9.6E-57 T 29-03-2018 GBCGDNIH2_RS00100 1ce09df2bd5b98a2134afe13b37f87c8 262 Pfam PF00005 ABC transporter 40 187 2.0E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GBCGDNIH2_RS00100 1ce09df2bd5b98a2134afe13b37f87c8 262 PIRSF PIRSF039085 21 262 6.0E-81 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 GBCGDNIH2_RS00100 1ce09df2bd5b98a2134afe13b37f87c8 262 SUPERFAMILY SSF52540 25 258 1.16E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS00100 1ce09df2bd5b98a2134afe13b37f87c8 262 SMART SM00382 49 236 5.4E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS10260 0673dc9007af4e5fd5ec4eb20e11ddd6 362 SUPERFAMILY SSF53474 215 226 2.81E-40 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS10260 0673dc9007af4e5fd5ec4eb20e11ddd6 362 SUPERFAMILY SSF53474 255 332 2.81E-40 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS10260 0673dc9007af4e5fd5ec4eb20e11ddd6 362 SUPERFAMILY SSF53474 52 187 2.81E-40 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS10260 0673dc9007af4e5fd5ec4eb20e11ddd6 362 Gene3D G3DSA:3.40.50.1820 43 341 7.8E-39 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS10260 0673dc9007af4e5fd5ec4eb20e11ddd6 362 Pfam PF12146 Serine aminopeptidase, S33 75 319 8.7E-46 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 GBCGDNIH2_RS10260 0673dc9007af4e5fd5ec4eb20e11ddd6 362 PRINTS PR00111 Alpha/beta hydrolase fold signature 103 118 2.8E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 GBCGDNIH2_RS10260 0673dc9007af4e5fd5ec4eb20e11ddd6 362 PRINTS PR00111 Alpha/beta hydrolase fold signature 151 164 2.8E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 GBCGDNIH2_RS10260 0673dc9007af4e5fd5ec4eb20e11ddd6 362 PRINTS PR00111 Alpha/beta hydrolase fold signature 264 278 2.8E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 GBCGDNIH2_RS07520 db8b9f90989d2e2100db12466f28fc1f 122 SUPERFAMILY SSF53254 1 109 2.86E-14 T 29-03-2018 IPR029033 Histidine phosphatase superfamily GBCGDNIH2_RS07520 db8b9f90989d2e2100db12466f28fc1f 122 Gene3D G3DSA:3.40.50.1240 1 114 9.7E-15 T 29-03-2018 IPR029033 Histidine phosphatase superfamily GBCGDNIH2_RS04990 ee8ba2ee0943ded07bcafff163eae5bf 428 SUPERFAMILY SSF103473 11 409 4.58E-19 T 29-03-2018 IPR020846 Major facilitator superfamily domain GBCGDNIH2_RS04990 ee8ba2ee0943ded07bcafff163eae5bf 428 Gene3D G3DSA:1.20.1250.20 1 203 3.8E-12 T 29-03-2018 GBCGDNIH2_RS04990 ee8ba2ee0943ded07bcafff163eae5bf 428 Gene3D G3DSA:1.20.1250.20 215 417 0.008 T 29-03-2018 GBCGDNIH2_RS04990 ee8ba2ee0943ded07bcafff163eae5bf 428 Pfam PF07690 Major Facilitator Superfamily 16 373 1.7E-14 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 GBCGDNIH2_RS06535 14b9230ba3ae0861817112d6f1e41d3c 487 Gene3D G3DSA:3.40.50.300 5 424 8.2E-21 T 29-03-2018 GBCGDNIH2_RS06535 14b9230ba3ae0861817112d6f1e41d3c 487 PIRSF PIRSF034081 1 487 2.1E-232 T 29-03-2018 IPR014588 ATPase, Atu1862 type, predicted GBCGDNIH2_RS06535 14b9230ba3ae0861817112d6f1e41d3c 487 SUPERFAMILY SSF52540 4 250 7.19E-27 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS06535 14b9230ba3ae0861817112d6f1e41d3c 487 Pfam PF01935 Domain of unknown function DUF87 8 77 1.1E-8 T 29-03-2018 IPR002789 Helicase HerA, central domain GBCGDNIH2_RS09110 29edd8a24b4a16971770a1a778c73573 542 Pfam PF02867 Ribonucleotide reductase, barrel domain 180 312 1.6E-4 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 GBCGDNIH2_RS09110 29edd8a24b4a16971770a1a778c73573 542 Gene3D G3DSA:3.20.70.20 145 338 9.7E-9 T 29-03-2018 GBCGDNIH2_RS09110 29edd8a24b4a16971770a1a778c73573 542 SUPERFAMILY SSF51998 145 311 1.14E-9 T 29-03-2018 GBCGDNIH2_RS03430 77675c44f58c3b109fa9a5207fdba3de 423 Gene3D G3DSA:1.20.1600.10 42 310 1.9E-23 T 29-03-2018 GBCGDNIH2_RS03430 77675c44f58c3b109fa9a5207fdba3de 423 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 66 405 3.5E-67 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 GBCGDNIH2_RS03430 77675c44f58c3b109fa9a5207fdba3de 423 SUPERFAMILY SSF111369 78 327 9.29E-57 T 29-03-2018 GBCGDNIH2_RS03430 77675c44f58c3b109fa9a5207fdba3de 423 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 79 305 2.8E-9 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain GBCGDNIH2_RS06345 931160db08ce6c21bab46cb09dd424fb 343 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 43 324 6.0E-46 T 29-03-2018 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system GBCGDNIH2_RS01240 ecef970b057e2d289046da112e991bff 289 Gene3D G3DSA:3.40.50.10320 9 269 2.6E-10 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 GBCGDNIH2_RS01240 ecef970b057e2d289046da112e991bff 289 SUPERFAMILY SSF102588 14 226 4.71E-7 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 GBCGDNIH2_RS06350 d5583555a2618e3a20c3916b6a6203f1 690 Gene3D G3DSA:3.40.50.300 2 412 9.4E-22 T 29-03-2018 GBCGDNIH2_RS06350 d5583555a2618e3a20c3916b6a6203f1 690 SUPERFAMILY SSF52540 288 402 6.71E-16 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS06350 d5583555a2618e3a20c3916b6a6203f1 690 SUPERFAMILY SSF52540 1 164 6.71E-16 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS06350 d5583555a2618e3a20c3916b6a6203f1 690 Pfam PF13175 AAA ATPase domain 1 98 5.1E-16 T 29-03-2018 GBCGDNIH2_RS06350 d5583555a2618e3a20c3916b6a6203f1 690 Pfam PF13175 AAA ATPase domain 198 400 5.8E-30 T 29-03-2018 GBCGDNIH2_RS00070 698f3422826c87098d5d5df901ee0c88 674 SUPERFAMILY SSF52833 7 136 3.11E-30 T 29-03-2018 IPR012336 Thioredoxin-like fold GBCGDNIH2_RS00070 698f3422826c87098d5d5df901ee0c88 674 SUPERFAMILY SSF48208 183 538 3.12E-65 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 GBCGDNIH2_RS00070 698f3422826c87098d5d5df901ee0c88 674 Gene3D G3DSA:1.50.10.10 529 672 6.0E-4 T 29-03-2018 GBCGDNIH2_RS00070 698f3422826c87098d5d5df901ee0c88 674 Gene3D G3DSA:1.50.10.10 318 528 6.0E-39 T 29-03-2018 GBCGDNIH2_RS00070 698f3422826c87098d5d5df901ee0c88 674 Gene3D G3DSA:3.40.30.10 7 179 5.5E-28 T 29-03-2018 GBCGDNIH2_RS00070 698f3422826c87098d5d5df901ee0c88 674 PIRSF PIRSF006402 1 674 9.4E-191 T 29-03-2018 IPR024705 Spermatogenesis-associated protein 20 GBCGDNIH2_RS00070 698f3422826c87098d5d5df901ee0c88 674 Pfam PF03190 Protein of unknown function, DUF255 9 170 2.7E-73 T 29-03-2018 IPR004879 Domain of unknown function DUF255 GBCGDNIH2_RS00070 698f3422826c87098d5d5df901ee0c88 674 Gene3D G3DSA:1.50.10.10 218 317 7.2E-15 T 29-03-2018 GBCGDNIH2_RS10230 62540a702d722b4d342288f0d25ab4de 171 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 6 144 2.8E-60 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 GBCGDNIH2_RS10230 62540a702d722b4d342288f0d25ab4de 171 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 171 70.935 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 GBCGDNIH2_RS10230 62540a702d722b4d342288f0d25ab4de 171 Gene3D G3DSA:3.40.50.9100 1 148 1.1E-63 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 GBCGDNIH2_RS10230 62540a702d722b4d342288f0d25ab4de 171 ProSitePatterns PS01029 Dehydroquinase class II signature. 9 26 - T 29-03-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 GBCGDNIH2_RS10230 62540a702d722b4d342288f0d25ab4de 171 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 6 134 7.0E-47 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 GBCGDNIH2_RS10230 62540a702d722b4d342288f0d25ab4de 171 PIRSF PIRSF001399 2 148 4.4E-62 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 GBCGDNIH2_RS10230 62540a702d722b4d342288f0d25ab4de 171 Pfam PF01220 Dehydroquinase class II 6 141 2.2E-58 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 GBCGDNIH2_RS10230 62540a702d722b4d342288f0d25ab4de 171 SUPERFAMILY SSF52304 6 153 3.01E-61 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 GBCGDNIH2_RS09915 9f1a34427bec8b77e1367cda2e172d11 269 SUPERFAMILY SSF161098 19 260 4.32E-48 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GBCGDNIH2_RS09915 9f1a34427bec8b77e1367cda2e172d11 269 Gene3D G3DSA:1.10.3720.10 11 269 8.4E-37 T 29-03-2018 GBCGDNIH2_RS09915 9f1a34427bec8b77e1367cda2e172d11 269 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 15 264 2.2E-82 T 29-03-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 GBCGDNIH2_RS09915 9f1a34427bec8b77e1367cda2e172d11 269 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 74 264 1.7E-14 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GBCGDNIH2_RS03505 da0b47dfe0e8d0173ba886e12cb8bdcf 383 Gene3D G3DSA:3.40.630.10 269 378 4.6E-5 T 29-03-2018 GBCGDNIH2_RS03505 da0b47dfe0e8d0173ba886e12cb8bdcf 383 Gene3D G3DSA:3.40.630.10 2 268 1.2E-52 T 29-03-2018 GBCGDNIH2_RS03505 da0b47dfe0e8d0173ba886e12cb8bdcf 383 Pfam PF01546 Peptidase family M20/M25/M40 64 374 8.5E-34 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 GBCGDNIH2_RS03505 da0b47dfe0e8d0173ba886e12cb8bdcf 383 Pfam PF07687 Peptidase dimerisation domain 172 278 2.8E-19 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain GBCGDNIH2_RS03505 da0b47dfe0e8d0173ba886e12cb8bdcf 383 TIGRFAM TIGR01246 dapE_proteo: succinyl-diaminopimelate desuccinylase 6 374 1.6E-120 T 29-03-2018 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 GBCGDNIH2_RS03505 da0b47dfe0e8d0173ba886e12cb8bdcf 383 Hamap MF_01690 Succinyl-diaminopimelate desuccinylase [dapE]. 2 379 47.994 T 29-03-2018 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 GBCGDNIH2_RS03505 da0b47dfe0e8d0173ba886e12cb8bdcf 383 SUPERFAMILY SSF53187 2 175 4.78E-53 T 29-03-2018 GBCGDNIH2_RS03505 da0b47dfe0e8d0173ba886e12cb8bdcf 383 SUPERFAMILY SSF53187 297 375 4.78E-53 T 29-03-2018 GBCGDNIH2_RS03505 da0b47dfe0e8d0173ba886e12cb8bdcf 383 SUPERFAMILY SSF55031 176 278 4.49E-24 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain GBCGDNIH2_RS11050 13481108bbdd102a4f6a4641f5f4cc76 367 Pfam PF00005 ABC transporter 26 162 1.8E-24 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GBCGDNIH2_RS11050 13481108bbdd102a4f6a4641f5f4cc76 367 Pfam PF03459 TOBE domain 320 363 2.8E-10 T 29-03-2018 IPR005116 Transport-associated OB, type 1 GBCGDNIH2_RS11050 13481108bbdd102a4f6a4641f5f4cc76 367 TIGRFAM TIGR02142 modC_ABC: molybdate ABC transporter, ATP-binding protein 7 362 4.5E-103 T 29-03-2018 IPR011868 Molybdate ABC transporter, ATP-binding protein GO:0005524|GO:0015098|GO:0015689|GO:0016020 GBCGDNIH2_RS11050 13481108bbdd102a4f6a4641f5f4cc76 367 SMART SM00382 25 211 5.0E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS11050 13481108bbdd102a4f6a4641f5f4cc76 367 SUPERFAMILY SSF50331 239 364 8.82E-15 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal GBCGDNIH2_RS11050 13481108bbdd102a4f6a4641f5f4cc76 367 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GBCGDNIH2_RS11050 13481108bbdd102a4f6a4641f5f4cc76 367 Gene3D G3DSA:2.40.50.100 286 361 2.7E-17 T 29-03-2018 GBCGDNIH2_RS11050 13481108bbdd102a4f6a4641f5f4cc76 367 SUPERFAMILY SSF52540 19 226 2.17E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS11050 13481108bbdd102a4f6a4641f5f4cc76 367 Gene3D G3DSA:3.40.50.300 17 285 1.2E-52 T 29-03-2018 GBCGDNIH2_RS02740 c99cf924f8ed7a682217c31b7a506f96 327 SUPERFAMILY SSF74653 243 319 7.72E-12 T 29-03-2018 GBCGDNIH2_RS02740 c99cf924f8ed7a682217c31b7a506f96 327 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 249 323 1.1E-12 T 29-03-2018 IPR006260 TonB, C-terminal GO:0006810 GBCGDNIH2_RS02740 c99cf924f8ed7a682217c31b7a506f96 327 PRINTS PR01217 Proline rich extensin signature 72 93 2.5E-10 T 29-03-2018 GBCGDNIH2_RS02740 c99cf924f8ed7a682217c31b7a506f96 327 PRINTS PR01217 Proline rich extensin signature 101 117 2.5E-10 T 29-03-2018 GBCGDNIH2_RS02740 c99cf924f8ed7a682217c31b7a506f96 327 PRINTS PR01217 Proline rich extensin signature 118 135 2.5E-10 T 29-03-2018 GBCGDNIH2_RS02740 c99cf924f8ed7a682217c31b7a506f96 327 Gene3D G3DSA:3.30.1150.10 78 323 7.9E-14 T 29-03-2018 GBCGDNIH2_RS02740 c99cf924f8ed7a682217c31b7a506f96 327 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 249 318 5.9E-12 T 29-03-2018 IPR006260 TonB, C-terminal GO:0006810 GBCGDNIH2_RS11595 e5abe295aa5c13556dee1b41281adc5f 152 Gene3D G3DSA:3.90.1010.10 3 146 2.5E-41 T 29-03-2018 GBCGDNIH2_RS11595 e5abe295aa5c13556dee1b41281adc5f 152 Pfam PF02657 Fe-S metabolism associated domain 23 141 1.4E-37 T 29-03-2018 IPR003808 Fe-S metabolism associated domain, SufE-like GBCGDNIH2_RS11595 e5abe295aa5c13556dee1b41281adc5f 152 SUPERFAMILY SSF82649 12 144 1.2E-37 T 29-03-2018 GBCGDNIH2_RS10085 1068f91aaa78bd7bceb847da664553d7 155 PIRSF PIRSF000216 1 155 1.0E-45 T 29-03-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS10085 1068f91aaa78bd7bceb847da664553d7 155 Gene3D G3DSA:3.40.30.10 73 155 4.5E-13 T 29-03-2018 GBCGDNIH2_RS10085 1068f91aaa78bd7bceb847da664553d7 155 SUPERFAMILY SSF52833 7 154 1.45E-46 T 29-03-2018 IPR012336 Thioredoxin-like fold GBCGDNIH2_RS10085 1068f91aaa78bd7bceb847da664553d7 155 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 12 154 1.0E-42 T 29-03-2018 GBCGDNIH2_RS00415 642871c913e51de67a21d58e128cecee 417 Gene3D G3DSA:3.50.50.60 30 417 6.7E-44 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS00415 642871c913e51de67a21d58e128cecee 417 SUPERFAMILY SSF54373 262 341 6.47E-5 T 29-03-2018 GBCGDNIH2_RS00415 642871c913e51de67a21d58e128cecee 417 SUPERFAMILY SSF51905 345 405 6.35E-50 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS00415 642871c913e51de67a21d58e128cecee 417 SUPERFAMILY SSF51905 33 255 6.35E-50 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS00415 642871c913e51de67a21d58e128cecee 417 Pfam PF01266 FAD dependent oxidoreductase 34 382 9.2E-61 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 GBCGDNIH2_RS00415 642871c913e51de67a21d58e128cecee 417 TIGRFAM TIGR01373 soxB: sarcosine oxidase, beta subunit family 3 409 2.4E-215 T 29-03-2018 IPR006278 Sarcosine oxidase subunit beta GO:0008115|GO:0046653|GO:0055114 KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 GBCGDNIH2_RS10420 cc10ce9b4639ca3f81896a0b8fa7af3b 446 Gene3D G3DSA:3.40.50.1820 97 446 2.9E-30 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS10420 cc10ce9b4639ca3f81896a0b8fa7af3b 446 SUPERFAMILY SSF53474 153 444 1.03E-33 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS10420 cc10ce9b4639ca3f81896a0b8fa7af3b 446 Pfam PF00561 alpha/beta hydrolase fold 161 423 2.3E-14 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 GBCGDNIH2_RS07400 2cc11a2a2f3d68c1c1dfb3401126b2d3 137 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 99 123 - T 29-03-2018 IPR020458 Zinc finger, DksA/TraR C4-type conserved site GBCGDNIH2_RS07400 2cc11a2a2f3d68c1c1dfb3401126b2d3 137 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 94 129 2.3E-12 T 29-03-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 GBCGDNIH2_RS07400 2cc11a2a2f3d68c1c1dfb3401126b2d3 137 Hamap MF_00926 RNA polymerase-binding transcription factor DksA [dksA]. 13 135 27.454 T 29-03-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 GBCGDNIH2_RS07400 2cc11a2a2f3d68c1c1dfb3401126b2d3 137 SUPERFAMILY SSF57716 96 134 4.85E-9 T 29-03-2018 GBCGDNIH2_RS07400 2cc11a2a2f3d68c1c1dfb3401126b2d3 137 TIGRFAM TIGR02420 dksA: RNA polymerase-binding protein DksA 17 126 2.6E-43 T 29-03-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 GBCGDNIH2_RS07400 2cc11a2a2f3d68c1c1dfb3401126b2d3 137 SUPERFAMILY SSF109635 3 95 4.45E-30 T 29-03-2018 GBCGDNIH2_RS04640 54aa13d73f439ccc65deca57b19562f2 297 SUPERFAMILY SSF53187 16 288 4.24E-79 T 29-03-2018 GBCGDNIH2_RS04640 54aa13d73f439ccc65deca57b19562f2 297 Gene3D G3DSA:3.40.630.40 3 293 2.4E-73 T 29-03-2018 GBCGDNIH2_RS04640 54aa13d73f439ccc65deca57b19562f2 297 Pfam PF05013 N-formylglutamate amidohydrolase 25 261 2.0E-65 T 29-03-2018 IPR007709 N-formylglutamate amidohydrolase GBCGDNIH2_RS01320 fe0af948b0fddc585b22463bfddd1678 107 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 2 96 22.146 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family GBCGDNIH2_RS01320 fe0af948b0fddc585b22463bfddd1678 107 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 3 103 1.1E-27 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family GBCGDNIH2_RS01320 fe0af948b0fddc585b22463bfddd1678 107 PIRSF PIRSF004555 1 107 1.3E-37 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family GBCGDNIH2_RS01320 fe0af948b0fddc585b22463bfddd1678 107 Gene3D G3DSA:3.30.1310.10 1 107 4.2E-42 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family GBCGDNIH2_RS01320 fe0af948b0fddc585b22463bfddd1678 107 SUPERFAMILY SSF82607 8 101 3.66E-32 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family GBCGDNIH2_RS01320 fe0af948b0fddc585b22463bfddd1678 107 Pfam PF02575 YbaB/EbfC DNA-binding family 8 98 1.2E-33 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family GBCGDNIH2_RS03670 d20b2f5f69f48c1dd40161712743b30e 318 Gene3D G3DSA:3.90.550.10 1 210 5.2E-32 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS03670 d20b2f5f69f48c1dd40161712743b30e 318 Pfam PF00535 Glycosyl transferase family 2 1 162 8.8E-31 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 GBCGDNIH2_RS03670 d20b2f5f69f48c1dd40161712743b30e 318 SUPERFAMILY SSF53448 1 223 2.32E-34 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS05605 4d2133f0ed8b4bd2bdd350d1a4dad352 280 SUPERFAMILY SSF53335 15 245 4.14E-18 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GBCGDNIH2_RS05605 4d2133f0ed8b4bd2bdd350d1a4dad352 280 Pfam PF13489 Methyltransferase domain 39 241 5.8E-13 T 29-03-2018 GBCGDNIH2_RS05605 4d2133f0ed8b4bd2bdd350d1a4dad352 280 Gene3D G3DSA:3.40.50.150 14 269 1.8E-16 T 29-03-2018 GBCGDNIH2_RS06015 aaeb244c5cbf2733e5a70486ca4130e0 273 Pfam PF08543 Phosphomethylpyrimidine kinase 12 261 3.1E-86 T 29-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 GBCGDNIH2_RS06015 aaeb244c5cbf2733e5a70486ca4130e0 273 SUPERFAMILY SSF53613 2 264 6.24E-79 T 29-03-2018 IPR029056 Ribokinase-like GBCGDNIH2_RS06015 aaeb244c5cbf2733e5a70486ca4130e0 273 Gene3D G3DSA:3.40.1190.20 1 271 1.5E-61 T 29-03-2018 IPR029056 Ribokinase-like GBCGDNIH2_RS06015 aaeb244c5cbf2733e5a70486ca4130e0 273 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 5 262 2.5E-87 T 29-03-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 GBCGDNIH2_RS10120 36949d94476d070ee995104f2a26ec15 299 SUPERFAMILY SSF46785 1 87 5.99E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS10120 36949d94476d070ee995104f2a26ec15 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.9E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS10120 36949d94476d070ee995104f2a26ec15 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.9E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS10120 36949d94476d070ee995104f2a26ec15 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.9E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS10120 36949d94476d070ee995104f2a26ec15 299 Pfam PF03466 LysR substrate binding domain 87 287 1.6E-34 T 29-03-2018 IPR005119 LysR, substrate-binding GBCGDNIH2_RS10120 36949d94476d070ee995104f2a26ec15 299 SUPERFAMILY SSF53850 87 293 6.63E-31 T 29-03-2018 GBCGDNIH2_RS10120 36949d94476d070ee995104f2a26ec15 299 Gene3D G3DSA:3.40.190.10 88 174 7.2E-15 T 29-03-2018 GBCGDNIH2_RS10120 36949d94476d070ee995104f2a26ec15 299 Gene3D G3DSA:3.40.190.10 175 262 9.0E-11 T 29-03-2018 GBCGDNIH2_RS10120 36949d94476d070ee995104f2a26ec15 299 Gene3D G3DSA:1.10.10.10 1 80 6.2E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS10120 36949d94476d070ee995104f2a26ec15 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 6.9E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GBCGDNIH2_RS01780 3b561d8827c3fa90d5e5557ec40a7581 180 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 29 174 5.9E-27 T 29-03-2018 IPR019587 Polyketide cyclase/dehydrase GBCGDNIH2_RS01780 3b561d8827c3fa90d5e5557ec40a7581 180 Gene3D G3DSA:3.30.530.20 13 180 8.8E-30 T 29-03-2018 IPR023393 START-like domain GBCGDNIH2_RS01780 3b561d8827c3fa90d5e5557ec40a7581 180 SUPERFAMILY SSF55961 29 178 4.95E-26 T 29-03-2018 GBCGDNIH2_RS10960 3b9e9e02dfbb72390306526b5c70736a 414 Gene3D G3DSA:3.50.50.60 2 413 4.3E-31 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS10960 3b9e9e02dfbb72390306526b5c70736a 414 SUPERFAMILY SSF51905 368 412 9.99E-42 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS10960 3b9e9e02dfbb72390306526b5c70736a 414 SUPERFAMILY SSF51905 4 280 9.99E-42 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS10960 3b9e9e02dfbb72390306526b5c70736a 414 Pfam PF01593 Flavin containing amine oxidoreductase 9 408 9.0E-35 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 GBCGDNIH2_RS10960 3b9e9e02dfbb72390306526b5c70736a 414 TIGRFAM TIGR03467 HpnE: squalene-associated FAD-dependent desaturase 3 412 2.3E-115 T 29-03-2018 IPR017830 Squalene-associated FAD-dependent desaturase GBCGDNIH2_RS03535 c1f90d44893789c5dbc2f76dc0194391 151 SUPERFAMILY SSF49764 29 133 2.02E-18 T 29-03-2018 IPR008978 HSP20-like chaperone GBCGDNIH2_RS03535 c1f90d44893789c5dbc2f76dc0194391 151 Pfam PF00011 Hsp20/alpha crystallin family 43 133 2.3E-16 T 29-03-2018 IPR002068 Alpha crystallin/Hsp20 domain GBCGDNIH2_RS03535 c1f90d44893789c5dbc2f76dc0194391 151 Gene3D G3DSA:2.60.40.790 2 134 1.6E-19 T 29-03-2018 IPR008978 HSP20-like chaperone GBCGDNIH2_RS02135 0dbb3b434b7fb732785b184d41acafa9 179 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 14 22 - T 29-03-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 GBCGDNIH2_RS02135 0dbb3b434b7fb732785b184d41acafa9 179 Gene3D G3DSA:3.40.50.1170 9 176 1.1E-27 T 29-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 GBCGDNIH2_RS02135 0dbb3b434b7fb732785b184d41acafa9 179 SUPERFAMILY SSF53774 11 174 2.36E-32 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 GBCGDNIH2_RS02135 0dbb3b434b7fb732785b184d41acafa9 179 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 87 97 - T 29-03-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 GBCGDNIH2_RS02135 0dbb3b434b7fb732785b184d41acafa9 179 PRINTS PR00139 Asparaginase/glutaminase family signature 86 104 2.3E-8 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 GBCGDNIH2_RS02135 0dbb3b434b7fb732785b184d41acafa9 179 PRINTS PR00139 Asparaginase/glutaminase family signature 12 23 2.3E-8 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 GBCGDNIH2_RS02135 0dbb3b434b7fb732785b184d41acafa9 179 Pfam PF00710 Asparaginase, N-terminal 12 172 8.5E-26 T 29-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 GBCGDNIH2_RS00515 0c6fdc3a14caef1a074a85d57e320e2d 349 SUPERFAMILY SSF51735 1 333 1.67E-97 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS00515 0c6fdc3a14caef1a074a85d57e320e2d 349 Gene3D G3DSA:3.40.50.720 1 191 3.7E-42 T 29-03-2018 GBCGDNIH2_RS00515 0c6fdc3a14caef1a074a85d57e320e2d 349 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 2 334 7.3E-136 T 29-03-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 GBCGDNIH2_RS00515 0c6fdc3a14caef1a074a85d57e320e2d 349 Gene3D G3DSA:3.90.25.10 192 345 6.2E-46 T 29-03-2018 GBCGDNIH2_RS00515 0c6fdc3a14caef1a074a85d57e320e2d 349 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 GBCGDNIH2_RS00515 0c6fdc3a14caef1a074a85d57e320e2d 349 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 321 1.8E-90 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS02610 dedfeadb1e218d0e70c00bf38338beee 433 Hamap MF_01232 UPF0229 protein YeaH [yeaH]. 1 423 35.483 T 29-03-2018 IPR006698 Uncharacterised protein family UPF0229 GBCGDNIH2_RS02610 dedfeadb1e218d0e70c00bf38338beee 433 Pfam PF04285 Protein of unknown function (DUF444) 3 420 3.0E-164 T 29-03-2018 IPR006698 Uncharacterised protein family UPF0229 GBCGDNIH2_RS06770 5e712b4705d752576af1da65c8e4175b 352 SUPERFAMILY SSF110997 270 347 7.59E-6 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 GBCGDNIH2_RS06770 5e712b4705d752576af1da65c8e4175b 352 Gene3D G3DSA:3.30.70.1070 267 351 1.2E-13 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 GBCGDNIH2_RS06770 5e712b4705d752576af1da65c8e4175b 352 Pfam PF05036 Sporulation related domain 271 349 1.2E-12 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 GBCGDNIH2_RS06540 fabdb468fb47edd1d57f37cbf236599b 314 Hamap MF_01206 Protein-methionine-sulfoxide reductase catalytic subunit MsrP [msrP]. 9 313 51.204 T 29-03-2018 IPR022867 Protein-methionine-sulfoxide reductase subunit MsrP GO:0016667|GO:0030091|GO:0043546|GO:0055114 GBCGDNIH2_RS06540 fabdb468fb47edd1d57f37cbf236599b 314 Pfam PF00174 Oxidoreductase molybdopterin binding domain 95 251 5.9E-31 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 GBCGDNIH2_RS06540 fabdb468fb47edd1d57f37cbf236599b 314 Gene3D G3DSA:3.90.420.10 54 313 1.2E-60 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 GBCGDNIH2_RS06540 fabdb468fb47edd1d57f37cbf236599b 314 SUPERFAMILY SSF56524 67 307 8.37E-86 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 GBCGDNIH2_RS01265 d1ed9f0d4d6d7be7a2b1a0e4aa1435d2 355 TIGRFAM TIGR04408 LptG_lptG: LPS export ABC transporter permease LptG 4 352 9.5E-94 T 29-03-2018 IPR030923 LPS export ABC transporter permease LptG GO:0043190|GO:0055085 GBCGDNIH2_RS01265 d1ed9f0d4d6d7be7a2b1a0e4aa1435d2 355 Pfam PF03739 Predicted permease YjgP/YjgQ family 5 352 2.6E-64 T 29-03-2018 IPR005495 Permease LptG/LptF-related GO:0016021 GBCGDNIH2_RS07700 5ebf589d61cd09f01d811d25ece53f7e 335 Gene3D G3DSA:3.40.50.720 3 143 1.5E-33 T 29-03-2018 GBCGDNIH2_RS07700 5ebf589d61cd09f01d811d25ece53f7e 335 SUPERFAMILY SSF55347 164 253 2.35E-14 T 29-03-2018 GBCGDNIH2_RS07700 5ebf589d61cd09f01d811d25ece53f7e 335 SUPERFAMILY SSF51735 8 167 1.53E-36 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS07700 5ebf589d61cd09f01d811d25ece53f7e 335 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 14 129 4.0E-25 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 GBCGDNIH2_RS07700 5ebf589d61cd09f01d811d25ece53f7e 335 Gene3D G3DSA:3.30.360.10 144 325 1.6E-25 T 29-03-2018 GBCGDNIH2_RS07470 291b07284a7956734241d3c931b72525 148 Pfam PF04657 Putative inner membrane exporter, YdcZ 9 144 6.3E-33 T 29-03-2018 IPR006750 Putative inner membrane exporter, YdcZ GBCGDNIH2_RS10375 f992af4c9866be02a8897c2ebdd68778 278 PIRSF PIRSF006487 3 110 3.2E-9 T 29-03-2018 GBCGDNIH2_RS10375 f992af4c9866be02a8897c2ebdd68778 278 PIRSF PIRSF006487 124 257 0.16 T 29-03-2018 GBCGDNIH2_RS10375 f992af4c9866be02a8897c2ebdd68778 278 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 187 247 9.7E-8 T 29-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 GBCGDNIH2_RS10375 f992af4c9866be02a8897c2ebdd68778 278 SUPERFAMILY SSF103025 6 202 6.12E-53 T 29-03-2018 GBCGDNIH2_RS10375 f992af4c9866be02a8897c2ebdd68778 278 Gene3D G3DSA:3.30.70.1400 121 200 3.4E-14 T 29-03-2018 GBCGDNIH2_RS10375 f992af4c9866be02a8897c2ebdd68778 278 Pfam PF01571 Aminomethyltransferase folate-binding domain 13 98 5.6E-9 T 29-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal GBCGDNIH2_RS10375 f992af4c9866be02a8897c2ebdd68778 278 Gene3D G3DSA:3.30.70.1400 13 98 9.8E-23 T 29-03-2018 GBCGDNIH2_RS10375 f992af4c9866be02a8897c2ebdd68778 278 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 147 212 6.2E-23 T 29-03-2018 IPR017703 YgfZ/GcvT conserved site GBCGDNIH2_RS00850 827b845f506bcf421f645cb6dce554d1 225 Pfam PF13409 Glutathione S-transferase, N-terminal domain 20 83 2.4E-10 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 GBCGDNIH2_RS00850 827b845f506bcf421f645cb6dce554d1 225 Gene3D G3DSA:1.20.1050.10 100 218 7.0E-15 T 29-03-2018 GBCGDNIH2_RS00850 827b845f506bcf421f645cb6dce554d1 225 SUPERFAMILY SSF52833 9 90 7.63E-15 T 29-03-2018 IPR012336 Thioredoxin-like fold GBCGDNIH2_RS00850 827b845f506bcf421f645cb6dce554d1 225 SUPERFAMILY SSF47616 88 212 6.54E-15 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like GBCGDNIH2_RS00850 827b845f506bcf421f645cb6dce554d1 225 Pfam PF13410 Glutathione S-transferase, C-terminal domain 137 208 4.0E-7 T 29-03-2018 GBCGDNIH2_RS00850 827b845f506bcf421f645cb6dce554d1 225 Gene3D G3DSA:3.40.30.10 2 99 1.6E-16 T 29-03-2018 GBCGDNIH2_RS10645 152a2bbcc1c302d06d78e71ea045ad0a 64 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 6 60 3.6E-17 T 29-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 GBCGDNIH2_RS10645 152a2bbcc1c302d06d78e71ea045ad0a 64 Gene3D G3DSA:1.20.5.1030 5 56 5.0E-18 T 29-03-2018 GBCGDNIH2_RS10645 152a2bbcc1c302d06d78e71ea045ad0a 64 Hamap MF_00422 Protein translocase subunit SecE [secE]. 3 58 12.522 T 29-03-2018 IPR022943 Preprotein translocase subunit SecE Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 GBCGDNIH2_RS10645 152a2bbcc1c302d06d78e71ea045ad0a 64 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 7 57 2.7E-17 T 29-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 GBCGDNIH2_RS01040 c08fe3d67031d5080c1ba9e3d11de5d1 275 Pfam PF04333 MlaA lipoprotein 54 249 3.0E-67 T 29-03-2018 IPR007428 MlaA lipoprotein GO:0016020 GBCGDNIH2_RS01040 c08fe3d67031d5080c1ba9e3d11de5d1 275 PRINTS PR01805 VacJ lipoprotein signature 55 68 1.0E-23 T 29-03-2018 IPR007428 MlaA lipoprotein GO:0016020 GBCGDNIH2_RS01040 c08fe3d67031d5080c1ba9e3d11de5d1 275 PRINTS PR01805 VacJ lipoprotein signature 123 140 1.0E-23 T 29-03-2018 IPR007428 MlaA lipoprotein GO:0016020 GBCGDNIH2_RS01040 c08fe3d67031d5080c1ba9e3d11de5d1 275 PRINTS PR01805 VacJ lipoprotein signature 159 176 1.0E-23 T 29-03-2018 IPR007428 MlaA lipoprotein GO:0016020 GBCGDNIH2_RS01040 c08fe3d67031d5080c1ba9e3d11de5d1 275 PRINTS PR01805 VacJ lipoprotein signature 72 88 1.0E-23 T 29-03-2018 IPR007428 MlaA lipoprotein GO:0016020 GBCGDNIH2_RS09925 b622530f6f22c6b5f962923b5bbb9ce0 251 SUPERFAMILY SSF52172 16 139 1.85E-41 T 29-03-2018 IPR011006 CheY-like superfamily GBCGDNIH2_RS09925 b622530f6f22c6b5f962923b5bbb9ce0 251 Gene3D G3DSA:1.10.10.10 142 251 6.4E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS09925 b622530f6f22c6b5f962923b5bbb9ce0 251 SUPERFAMILY SSF46894 145 247 5.67E-23 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 GBCGDNIH2_RS09925 b622530f6f22c6b5f962923b5bbb9ce0 251 Pfam PF00486 Transcriptional regulatory protein, C terminal 170 244 3.6E-18 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 GBCGDNIH2_RS09925 b622530f6f22c6b5f962923b5bbb9ce0 251 Gene3D G3DSA:3.40.50.2300 4 141 1.6E-35 T 29-03-2018 GBCGDNIH2_RS09925 b622530f6f22c6b5f962923b5bbb9ce0 251 SMART SM00862 168 244 6.3E-20 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 GBCGDNIH2_RS09925 b622530f6f22c6b5f962923b5bbb9ce0 251 SMART SM00448 18 128 2.9E-42 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GBCGDNIH2_RS09925 b622530f6f22c6b5f962923b5bbb9ce0 251 Pfam PF00072 Response regulator receiver domain 20 129 7.7E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GBCGDNIH2_RS05765 90a9ab67044f81d9d2a92514ac15b8fc 80 Pfam PF10038 Protein of unknown function (DUF2274) 1 70 1.0E-35 T 29-03-2018 IPR018733 Protein of unknown function DUF2274 GBCGDNIH2_RS03350 42173ad03264b07dc25af8599c232349 1124 Pfam PF02514 CobN/Magnesium Chelatase 717 1112 1.4E-130 T 29-03-2018 IPR003672 CobN/magnesium chelatase GO:0009058 GBCGDNIH2_RS03350 42173ad03264b07dc25af8599c232349 1124 Pfam PF02514 CobN/Magnesium Chelatase 146 706 3.2E-144 T 29-03-2018 IPR003672 CobN/magnesium chelatase GO:0009058 GBCGDNIH2_RS04120 8c6f5357b4090511f4379e53d12f6270 55 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 2 53 13.383 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS04120 8c6f5357b4090511f4379e53d12f6270 55 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 55 9.7E-23 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS04120 8c6f5357b4090511f4379e53d12f6270 55 Pfam PF00471 Ribosomal protein L33 7 53 8.9E-17 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GBCGDNIH2_RS04120 8c6f5357b4090511f4379e53d12f6270 55 ProSitePatterns PS00582 Ribosomal protein L33 signature. 21 40 - T 29-03-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 GBCGDNIH2_RS04120 8c6f5357b4090511f4379e53d12f6270 55 SUPERFAMILY SSF57829 1 53 5.74E-18 T 29-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 GBCGDNIH2_RS06495 4a0cb070e639c4b385c682b45951686e 409 Gene3D G3DSA:1.20.1250.20 22 210 6.7E-18 T 29-03-2018 GBCGDNIH2_RS06495 4a0cb070e639c4b385c682b45951686e 409 SUPERFAMILY SSF103473 26 407 1.83E-50 T 29-03-2018 IPR020846 Major facilitator superfamily domain GBCGDNIH2_RS06495 4a0cb070e639c4b385c682b45951686e 409 Gene3D G3DSA:1.20.1250.20 211 409 2.7E-21 T 29-03-2018 GBCGDNIH2_RS06495 4a0cb070e639c4b385c682b45951686e 409 Pfam PF07690 Major Facilitator Superfamily 34 357 1.1E-31 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 GBCGDNIH2_RS10850 962a193267f32bea1907ecc0ead23058 189 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 16 149 6.1E-43 T 29-03-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 GBCGDNIH2_RS10850 962a193267f32bea1907ecc0ead23058 189 SUPERFAMILY SSF52540 14 137 6.48E-25 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS10850 962a193267f32bea1907ecc0ead23058 189 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 16 148 5.7E-52 T 29-03-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 GBCGDNIH2_RS10850 962a193267f32bea1907ecc0ead23058 189 Gene3D G3DSA:3.40.50.300 10 184 2.9E-26 T 29-03-2018 GBCGDNIH2_RS11395 4ad0fb66c9697a1d07d02654595cb60a 468 Gene3D G3DSA:1.10.4030.10 66 191 4.6E-19 T 29-03-2018 GBCGDNIH2_RS11395 4ad0fb66c9697a1d07d02654595cb60a 468 Pfam PF09312 SurA N-terminal domain 72 180 1.7E-15 T 29-03-2018 IPR015391 SurA N-terminal GBCGDNIH2_RS11395 4ad0fb66c9697a1d07d02654595cb60a 468 Gene3D G3DSA:3.10.50.40 319 458 1.1E-4 T 29-03-2018 GBCGDNIH2_RS11395 4ad0fb66c9697a1d07d02654595cb60a 468 Pfam PF00639 PPIC-type PPIASE domain 225 309 2.9E-14 T 29-03-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 GBCGDNIH2_RS11395 4ad0fb66c9697a1d07d02654595cb60a 468 SUPERFAMILY SSF54534 335 426 3.66E-6 T 29-03-2018 GBCGDNIH2_RS11395 4ad0fb66c9697a1d07d02654595cb60a 468 SUPERFAMILY SSF109998 71 232 9.94E-34 T 29-03-2018 IPR027304 Trigger factor/SurA domain GBCGDNIH2_RS11395 4ad0fb66c9697a1d07d02654595cb60a 468 Gene3D G3DSA:3.10.50.40 209 318 1.6E-21 T 29-03-2018 GBCGDNIH2_RS11395 4ad0fb66c9697a1d07d02654595cb60a 468 SUPERFAMILY SSF54534 213 313 5.89E-22 T 29-03-2018 GBCGDNIH2_RS05775 a019efb3d6d29e701d93563a03406786 128 SUPERFAMILY SSF46785 45 116 1.05E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS05775 a019efb3d6d29e701d93563a03406786 128 Gene3D G3DSA:1.10.10.10 10 117 3.9E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS03855 b54e4bca19823947632126b4bfa11334 670 Gene3D G3DSA:3.20.20.80 137 667 9.6E-146 T 29-03-2018 GBCGDNIH2_RS03855 b54e4bca19823947632126b4bfa11334 670 Pfam PF02446 4-alpha-glucanotransferase 148 645 2.9E-109 T 29-03-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 GBCGDNIH2_RS03855 b54e4bca19823947632126b4bfa11334 670 SUPERFAMILY SSF51445 142 555 1.97E-132 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily GBCGDNIH2_RS03855 b54e4bca19823947632126b4bfa11334 670 SUPERFAMILY SSF51445 589 662 1.97E-132 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily GBCGDNIH2_RS03855 b54e4bca19823947632126b4bfa11334 670 TIGRFAM TIGR00217 malQ: 4-alpha-glucanotransferase 115 664 2.0E-99 T 29-03-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 GBCGDNIH2_RS00640 c132d34e832b15199bca3a067d1d14df 156 PIRSF PIRSF003174 4 155 1.3E-49 T 29-03-2018 IPR010292 Uncharacterised protein family CreA GBCGDNIH2_RS00640 c132d34e832b15199bca3a067d1d14df 156 Pfam PF05981 CreA protein 29 153 5.0E-45 T 29-03-2018 IPR010292 Uncharacterised protein family CreA GBCGDNIH2_RS09065 d491e4630a9266dc006ac701fce5613a 414 SUPERFAMILY SSF103473 16 407 7.46E-63 T 29-03-2018 IPR020846 Major facilitator superfamily domain GBCGDNIH2_RS09065 d491e4630a9266dc006ac701fce5613a 414 Gene3D G3DSA:1.20.1250.20 207 408 5.3E-30 T 29-03-2018 GBCGDNIH2_RS09065 d491e4630a9266dc006ac701fce5613a 414 Pfam PF07690 Major Facilitator Superfamily 27 365 4.8E-40 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 GBCGDNIH2_RS09065 d491e4630a9266dc006ac701fce5613a 414 Gene3D G3DSA:1.20.1250.20 17 206 8.5E-22 T 29-03-2018 GBCGDNIH2_RS09705 b6f3da0557267b70929c1ae3aa338c86 479 SUPERFAMILY SSF81340 35 461 3.79E-95 T 29-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 GBCGDNIH2_RS09705 b6f3da0557267b70929c1ae3aa338c86 479 Gene3D G3DSA:1.10.3080.10 29 464 1.7E-81 T 29-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 GBCGDNIH2_RS09705 b6f3da0557267b70929c1ae3aa338c86 479 PRINTS PR00762 Chloride channel signature 196 215 2.7E-33 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 GBCGDNIH2_RS09705 b6f3da0557267b70929c1ae3aa338c86 479 PRINTS PR00762 Chloride channel signature 366 386 2.7E-33 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 GBCGDNIH2_RS09705 b6f3da0557267b70929c1ae3aa338c86 479 PRINTS PR00762 Chloride channel signature 395 411 2.7E-33 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 GBCGDNIH2_RS09705 b6f3da0557267b70929c1ae3aa338c86 479 PRINTS PR00762 Chloride channel signature 110 127 2.7E-33 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 GBCGDNIH2_RS09705 b6f3da0557267b70929c1ae3aa338c86 479 PRINTS PR00762 Chloride channel signature 413 432 2.7E-33 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 GBCGDNIH2_RS09705 b6f3da0557267b70929c1ae3aa338c86 479 PRINTS PR00762 Chloride channel signature 144 163 2.7E-33 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 GBCGDNIH2_RS09705 b6f3da0557267b70929c1ae3aa338c86 479 Pfam PF00654 Voltage gated chloride channel 97 445 9.7E-88 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 GBCGDNIH2_RS05000 82110f2dd9cec9706a15e8979fa4d65f 118 SUPERFAMILY SSF55298 9 117 5.03E-26 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like GBCGDNIH2_RS05000 82110f2dd9cec9706a15e8979fa4d65f 118 Pfam PF01042 Endoribonuclease L-PSP 13 116 6.7E-18 T 29-03-2018 IPR006175 YjgF/YER057c/UK114 family GBCGDNIH2_RS05000 82110f2dd9cec9706a15e8979fa4d65f 118 Gene3D G3DSA:3.30.1330.40 3 118 1.4E-21 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like GBCGDNIH2_RS05820 7c3a53b3648ac737f654e544d13dbc34 229 SUPERFAMILY SSF52540 14 210 1.0E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS05820 7c3a53b3648ac737f654e544d13dbc34 229 Pfam PF02223 Thymidylate kinase 20 207 6.7E-40 T 29-03-2018 GBCGDNIH2_RS05820 7c3a53b3648ac737f654e544d13dbc34 229 Gene3D G3DSA:3.40.50.300 13 216 3.3E-46 T 29-03-2018 GBCGDNIH2_RS05820 7c3a53b3648ac737f654e544d13dbc34 229 Hamap MF_00165 Thymidylate kinase [tmk]. 16 217 26.002 T 29-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 GBCGDNIH2_RS05820 7c3a53b3648ac737f654e544d13dbc34 229 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 15 205 1.8E-41 T 29-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 GBCGDNIH2_RS05820 7c3a53b3648ac737f654e544d13dbc34 229 ProSitePatterns PS01331 Thymidylate kinase signature. 103 115 - T 29-03-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 GBCGDNIH2_RS04040 28a557bae118932ef8050373063095e9 536 Pfam PF02652 L-lactate permease 15 525 1.8E-132 T 29-03-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 GBCGDNIH2_RS04040 28a557bae118932ef8050373063095e9 536 TIGRFAM TIGR00795 lctP: transporter, lactate permease (LctP) family 15 526 2.2E-131 T 29-03-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 GBCGDNIH2_RS06085 255f4bbbe88891b4354ee912497f688c 277 SUPERFAMILY SSF56655 12 273 6.15E-53 T 29-03-2018 GBCGDNIH2_RS06085 255f4bbbe88891b4354ee912497f688c 277 PRINTS PR00377 Inositol monophosphatase superfamily signature 44 64 4.7E-18 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 GBCGDNIH2_RS06085 255f4bbbe88891b4354ee912497f688c 277 PRINTS PR00377 Inositol monophosphatase superfamily signature 66 82 4.7E-18 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 GBCGDNIH2_RS06085 255f4bbbe88891b4354ee912497f688c 277 PRINTS PR00377 Inositol monophosphatase superfamily signature 221 245 4.7E-18 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 GBCGDNIH2_RS06085 255f4bbbe88891b4354ee912497f688c 277 PRINTS PR00377 Inositol monophosphatase superfamily signature 93 109 4.7E-18 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 GBCGDNIH2_RS06085 255f4bbbe88891b4354ee912497f688c 277 Gene3D G3DSA:3.40.190.80 161 276 1.2E-14 T 29-03-2018 GBCGDNIH2_RS06085 255f4bbbe88891b4354ee912497f688c 277 Gene3D G3DSA:3.30.540.10 1 160 3.7E-30 T 29-03-2018 GBCGDNIH2_RS06085 255f4bbbe88891b4354ee912497f688c 277 Pfam PF00459 Inositol monophosphatase family 19 259 3.6E-36 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 GBCGDNIH2_RS09605 a7999005a055ca1b4aa78a7052d7d3da 308 Gene3D G3DSA:1.10.3470.10 8 305 3.4E-45 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like GBCGDNIH2_RS09605 a7999005a055ca1b4aa78a7052d7d3da 308 TIGRFAM TIGR03409 urea_trans_UrtB: urea ABC transporter, permease protein UrtB 16 307 1.2E-117 T 29-03-2018 IPR017779 ABC transporter, urea permease protein UrtB, bacterial-type GBCGDNIH2_RS09605 a7999005a055ca1b4aa78a7052d7d3da 308 Pfam PF02653 Branched-chain amino acid transport system / permease component 19 294 4.2E-45 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS07545 6f9f0d6fc645e13922b0d1c821fafd9c 446 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 1 441 24.486 T 29-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 GBCGDNIH2_RS07545 6f9f0d6fc645e13922b0d1c821fafd9c 446 Gene3D G3DSA:3.40.50.620 117 232 8.6E-21 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GBCGDNIH2_RS07545 6f9f0d6fc645e13922b0d1c821fafd9c 446 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 7 18 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 GBCGDNIH2_RS07545 6f9f0d6fc645e13922b0d1c821fafd9c 446 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 1 303 2.3E-69 T 29-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 GBCGDNIH2_RS07545 6f9f0d6fc645e13922b0d1c821fafd9c 446 Gene3D G3DSA:1.10.1160.10 233 315 1.5E-17 T 29-03-2018 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 GBCGDNIH2_RS07545 6f9f0d6fc645e13922b0d1c821fafd9c 446 SUPERFAMILY SSF48163 280 438 3.01E-30 T 29-03-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 GBCGDNIH2_RS07545 6f9f0d6fc645e13922b0d1c821fafd9c 446 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 1 321 2.4E-88 T 29-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 GBCGDNIH2_RS07545 6f9f0d6fc645e13922b0d1c821fafd9c 446 PRINTS PR00987 Glutamyl-tRNA synthetase signature 196 204 3.9E-22 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 GBCGDNIH2_RS07545 6f9f0d6fc645e13922b0d1c821fafd9c 446 PRINTS PR00987 Glutamyl-tRNA synthetase signature 180 190 3.9E-22 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 GBCGDNIH2_RS07545 6f9f0d6fc645e13922b0d1c821fafd9c 446 PRINTS PR00987 Glutamyl-tRNA synthetase signature 4 16 3.9E-22 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 GBCGDNIH2_RS07545 6f9f0d6fc645e13922b0d1c821fafd9c 446 PRINTS PR00987 Glutamyl-tRNA synthetase signature 18 29 3.9E-22 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 GBCGDNIH2_RS07545 6f9f0d6fc645e13922b0d1c821fafd9c 446 PRINTS PR00987 Glutamyl-tRNA synthetase signature 33 46 3.9E-22 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 GBCGDNIH2_RS07545 6f9f0d6fc645e13922b0d1c821fafd9c 446 Gene3D G3DSA:3.40.50.620 1 116 5.5E-32 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GBCGDNIH2_RS07545 6f9f0d6fc645e13922b0d1c821fafd9c 446 SUPERFAMILY SSF52374 1 297 6.97E-88 T 29-03-2018 GBCGDNIH2_RS07545 6f9f0d6fc645e13922b0d1c821fafd9c 446 Gene3D G3DSA:1.10.10.350 357 443 1.5E-18 T 29-03-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 GBCGDNIH2_RS08050 197d509f230dc53c2738730035ee6fd5 84 Pfam PF07927 HicA toxin of bacterial toxin-antitoxin, 23 73 8.9E-9 T 29-03-2018 IPR012933 HicA mRNA interferase family GO:0003729 GBCGDNIH2_RS04240 26bc5d10566930d5dd0059727e07dc42 249 ProSitePatterns PS00171 Triosephosphate isomerase active site. 164 174 - T 29-03-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GBCGDNIH2_RS04240 26bc5d10566930d5dd0059727e07dc42 249 Gene3D G3DSA:3.20.20.70 1 249 9.8E-90 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS04240 26bc5d10566930d5dd0059727e07dc42 249 SUPERFAMILY SSF51351 2 247 1.83E-84 T 29-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GBCGDNIH2_RS04240 26bc5d10566930d5dd0059727e07dc42 249 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 4 238 4.7E-54 T 29-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GBCGDNIH2_RS04240 26bc5d10566930d5dd0059727e07dc42 249 Pfam PF00121 Triosephosphate isomerase 4 244 8.7E-80 T 29-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GBCGDNIH2_RS04240 26bc5d10566930d5dd0059727e07dc42 249 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 1 248 37.609 T 29-03-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GBCGDNIH2_RS12525 a85c4298b90b1939f2b12d0d12213013 449 Pfam PF01494 FAD binding domain 21 332 1.1E-15 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 GBCGDNIH2_RS12525 a85c4298b90b1939f2b12d0d12213013 449 Gene3D G3DSA:3.30.9.10 192 358 4.2E-23 T 29-03-2018 GBCGDNIH2_RS12525 a85c4298b90b1939f2b12d0d12213013 449 SUPERFAMILY SSF51905 303 384 1.21E-39 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS12525 a85c4298b90b1939f2b12d0d12213013 449 SUPERFAMILY SSF51905 21 198 1.21E-39 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS12525 a85c4298b90b1939f2b12d0d12213013 449 Gene3D G3DSA:3.50.50.60 14 191 4.1E-20 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS04780 6cf90e25cb65277fd9d70b9644761664 600 Pfam PF03354 Phage Terminase 81 586 4.5E-47 T 29-03-2018 IPR005021 Terminase large subunit, Lambdalikevirus-type GBCGDNIH2_RS10930 1ce07eccc35b570dfb86832831be971d 141 Gene3D G3DSA:3.40.50.1010 1 130 1.5E-13 T 29-03-2018 IPR029060 PIN domain-like GBCGDNIH2_RS10930 1ce07eccc35b570dfb86832831be971d 141 Pfam PF01850 PIN domain 1 124 2.6E-13 T 29-03-2018 IPR002716 PIN domain GBCGDNIH2_RS10930 1ce07eccc35b570dfb86832831be971d 141 SUPERFAMILY SSF88723 1 127 3.08E-17 T 29-03-2018 IPR029060 PIN domain-like GBCGDNIH2_RS10930 1ce07eccc35b570dfb86832831be971d 141 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 1 130 10.458 T 29-03-2018 IPR022907 VapC family GO:0004540 GBCGDNIH2_RS08615 400b02d98fc89c638c0f9495a9956a3e 469 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 352 372 - T 29-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 GBCGDNIH2_RS08615 400b02d98fc89c638c0f9495a9956a3e 469 TIGRFAM TIGR03173 pbuX: xanthine permease 29 437 8.6E-148 T 29-03-2018 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 GBCGDNIH2_RS08615 400b02d98fc89c638c0f9495a9956a3e 469 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 23 435 3.7E-104 T 29-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 GBCGDNIH2_RS08615 400b02d98fc89c638c0f9495a9956a3e 469 Pfam PF00860 Permease family 26 404 1.8E-93 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 GBCGDNIH2_RS04270 11335806995a6f89386826ecccddcdf8 163 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 8 25 1.3E-22 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 GBCGDNIH2_RS04270 11335806995a6f89386826ecccddcdf8 163 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 125 140 1.3E-22 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 GBCGDNIH2_RS04270 11335806995a6f89386826ecccddcdf8 163 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 49 65 1.3E-22 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 GBCGDNIH2_RS04270 11335806995a6f89386826ecccddcdf8 163 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 83 98 1.3E-22 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 GBCGDNIH2_RS04270 11335806995a6f89386826ecccddcdf8 163 Gene3D G3DSA:3.40.50.2300 1 161 1.1E-44 T 29-03-2018 GBCGDNIH2_RS04270 11335806995a6f89386826ecccddcdf8 163 SMART SM00226 6 153 5.6E-39 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily GBCGDNIH2_RS04270 11335806995a6f89386826ecccddcdf8 163 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 8 147 2.2E-34 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily GBCGDNIH2_RS04270 11335806995a6f89386826ecccddcdf8 163 SUPERFAMILY SSF52788 7 150 3.14E-46 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily GBCGDNIH2_RS00620 933f77c353b40ba6e04ce463a5f73a90 598 SMART SM00564 133 165 0.0054 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat GBCGDNIH2_RS00620 933f77c353b40ba6e04ce463a5f73a90 598 SMART SM00564 179 216 2.5 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat GBCGDNIH2_RS00620 933f77c353b40ba6e04ce463a5f73a90 598 SMART SM00564 495 527 0.0053 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat GBCGDNIH2_RS00620 933f77c353b40ba6e04ce463a5f73a90 598 SMART SM00564 267 312 170.0 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat GBCGDNIH2_RS00620 933f77c353b40ba6e04ce463a5f73a90 598 SMART SM00564 81 114 1.6 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat GBCGDNIH2_RS00620 933f77c353b40ba6e04ce463a5f73a90 598 SUPERFAMILY SSF50998 35 595 2.62E-161 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily GBCGDNIH2_RS00620 933f77c353b40ba6e04ce463a5f73a90 598 Pfam PF13360 PQQ-like domain 66 217 9.2E-16 T 29-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat GBCGDNIH2_RS00620 933f77c353b40ba6e04ce463a5f73a90 598 Gene3D G3DSA:2.140.10.10 25 598 9.0E-111 T 29-03-2018 GBCGDNIH2_RS00620 933f77c353b40ba6e04ce463a5f73a90 598 ProSitePatterns PS00364 Bacterial quinoprotein dehydrogenases signature 2. 260 281 - T 29-03-2018 IPR001479 Quinoprotein dehydrogenase, conserved site GO:0030288|GO:0055114 GBCGDNIH2_RS00620 933f77c353b40ba6e04ce463a5f73a90 598 Pfam PF01011 PQQ enzyme repeat 501 534 1.1E-4 T 29-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat GBCGDNIH2_RS00620 933f77c353b40ba6e04ce463a5f73a90 598 TIGRFAM TIGR03075 PQQ_enz_alc_DH: PQQ-dependent dehydrogenase, methanol/ethanol family 32 555 2.3E-203 T 29-03-2018 IPR017512 PQQ-dependent dehydrogenase, methanol/ethanol family GO:0005509|GO:0016020|GO:0016614|GO:0055114 GBCGDNIH2_RS01165 889780b71e4e8137a441f904ed923745 398 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 61 296 3.6E-24 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain GBCGDNIH2_RS01165 889780b71e4e8137a441f904ed923745 398 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 47 377 2.5E-59 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 GBCGDNIH2_RS01165 889780b71e4e8137a441f904ed923745 398 SUPERFAMILY SSF111369 61 300 1.22E-29 T 29-03-2018 GBCGDNIH2_RS01165 889780b71e4e8137a441f904ed923745 398 Gene3D G3DSA:2.40.50.100 72 193 1.6E-14 T 29-03-2018 GBCGDNIH2_RS01165 889780b71e4e8137a441f904ed923745 398 Gene3D G3DSA:2.40.50.100 194 384 1.3E-4 T 29-03-2018 GBCGDNIH2_RS01865 3d8e912fb484424dc51a33e71a0e2283 525 Pfam PF14403 Circularly permuted ATP-grasp type 2 93 468 6.9E-158 T 29-03-2018 IPR025841 Circularly permuted ATP-grasp type 2 GBCGDNIH2_RS01865 3d8e912fb484424dc51a33e71a0e2283 525 SUPERFAMILY SSF56059 338 483 7.3E-60 T 29-03-2018 GBCGDNIH2_RS01865 3d8e912fb484424dc51a33e71a0e2283 525 SUPERFAMILY SSF56059 46 231 7.3E-60 T 29-03-2018 GBCGDNIH2_RS01865 3d8e912fb484424dc51a33e71a0e2283 525 Gene3D G3DSA:3.30.470.20 255 484 2.5E-5 T 29-03-2018 GBCGDNIH2_RS01865 3d8e912fb484424dc51a33e71a0e2283 525 PIRSF PIRSF005522 16 495 1.2E-205 T 29-03-2018 IPR016450 Uncharacterised conserved protein UCP005522 GBCGDNIH2_RS07300 62feea084acc4284a7ee5cde923365a4 67 Pfam PF04325 Protein of unknown function (DUF465) 13 58 4.4E-14 T 29-03-2018 IPR007420 Protein of unknown function DUF465 GBCGDNIH2_RS03910 fec4eca7104dc48b7668634b0b63a5d6 254 Gene3D G3DSA:3.90.190.10 29 201 4.4E-15 T 29-03-2018 IPR029021 Protein-tyrosine phosphatase-like GBCGDNIH2_RS03910 fec4eca7104dc48b7668634b0b63a5d6 254 SUPERFAMILY SSF52799 15 253 9.03E-44 T 29-03-2018 IPR029021 Protein-tyrosine phosphatase-like GBCGDNIH2_RS03910 fec4eca7104dc48b7668634b0b63a5d6 254 Pfam PF13350 Tyrosine phosphatase family 15 253 9.2E-56 T 29-03-2018 IPR026893 Tyrosine/serine-protein phosphatase IphP-type GBCGDNIH2_RS03910 fec4eca7104dc48b7668634b0b63a5d6 254 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 152 162 - T 29-03-2018 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311 GBCGDNIH2_RS02770 145d18fa489949d8edf85732ca34f68e 255 SUPERFAMILY SSF161098 52 235 7.19E-33 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GBCGDNIH2_RS02770 145d18fa489949d8edf85732ca34f68e 255 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 72 245 3.2E-27 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GBCGDNIH2_RS02770 145d18fa489949d8edf85732ca34f68e 255 Gene3D G3DSA:1.10.3720.10 11 250 8.3E-27 T 29-03-2018 GBCGDNIH2_RS06635 0ad5aad4d8c764ee1e7223e53fe190b0 143 Pfam PF06170 Protein of unknown function (DUF983) 28 110 2.3E-29 T 29-03-2018 IPR009325 Protein of unknown function DUF983 GBCGDNIH2_RS06520 4d6c4d76ffa88d1e693cd959564b2981 322 Gene3D G3DSA:3.40.50.1820 10 322 5.2E-16 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS06520 4d6c4d76ffa88d1e693cd959564b2981 322 Pfam PF12697 Alpha/beta hydrolase family 65 306 6.9E-11 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 GBCGDNIH2_RS06520 4d6c4d76ffa88d1e693cd959564b2981 322 SUPERFAMILY SSF53474 52 321 3.31E-22 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold GBCGDNIH2_RS11125 12078d52e06a3319a380e4cc54df619f 291 PRINTS PR00478 Phosphoribulokinase family signature 165 182 8.1E-31 T 29-03-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 GBCGDNIH2_RS11125 12078d52e06a3319a380e4cc54df619f 291 PRINTS PR00478 Phosphoribulokinase family signature 127 145 8.1E-31 T 29-03-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 GBCGDNIH2_RS11125 12078d52e06a3319a380e4cc54df619f 291 PRINTS PR00478 Phosphoribulokinase family signature 183 206 8.1E-31 T 29-03-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 GBCGDNIH2_RS11125 12078d52e06a3319a380e4cc54df619f 291 PRINTS PR00478 Phosphoribulokinase family signature 12 29 8.1E-31 T 29-03-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 GBCGDNIH2_RS11125 12078d52e06a3319a380e4cc54df619f 291 SUPERFAMILY SSF52540 3 286 3.43E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS11125 12078d52e06a3319a380e4cc54df619f 291 Gene3D G3DSA:3.40.50.300 1 290 7.3E-40 T 29-03-2018 GBCGDNIH2_RS11125 12078d52e06a3319a380e4cc54df619f 291 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 7 215 5.7E-70 T 29-03-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 Reactome: R-HSA-73614 GBCGDNIH2_RS12185 642c0e583750ff025fe90e71b3c1f3b0 470 Gene3D G3DSA:3.20.20.70 76 469 5.1E-4 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS12185 642c0e583750ff025fe90e71b3c1f3b0 470 SUPERFAMILY SSF51412 208 359 1.67E-6 T 29-03-2018 GBCGDNIH2_RS05580 534bf6d27a940757628dd22fe15491b0 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 70 3.5E-35 T 29-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 GBCGDNIH2_RS05580 534bf6d27a940757628dd22fe15491b0 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 3.3E-27 T 29-03-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 GBCGDNIH2_RS05580 534bf6d27a940757628dd22fe15491b0 72 Gene3D G3DSA:2.40.50.140 1 72 3.4E-37 T 29-03-2018 GBCGDNIH2_RS05580 534bf6d27a940757628dd22fe15491b0 72 SUPERFAMILY SSF50249 1 71 2.29E-27 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold GBCGDNIH2_RS05580 534bf6d27a940757628dd22fe15491b0 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 26.596 T 29-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 GBCGDNIH2_RS12435 df95ddc509d27650fe28f10cc1f47d68 227 SUPERFAMILY SSF53335 50 225 5.96E-22 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GBCGDNIH2_RS12435 df95ddc509d27650fe28f10cc1f47d68 227 Pfam PF02390 Putative methyltransferase 50 218 6.4E-34 T 29-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 GBCGDNIH2_RS12435 df95ddc509d27650fe28f10cc1f47d68 227 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 15 227 25.455 T 29-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 GBCGDNIH2_RS12435 df95ddc509d27650fe28f10cc1f47d68 227 Gene3D G3DSA:3.40.50.150 11 227 1.7E-16 T 29-03-2018 GBCGDNIH2_RS06290 3f66b10718c74d53da95991a564821f0 108 Gene3D G3DSA:3.30.429.10 1 94 5.0E-4 T 29-03-2018 GBCGDNIH2_RS11345 0d6829d8c067a5255d522b455c60cd86 315 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 86 257 9.4E-13 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain GBCGDNIH2_RS11345 0d6829d8c067a5255d522b455c60cd86 315 SUPERFAMILY SSF52266 82 268 3.66E-31 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain GBCGDNIH2_RS11345 0d6829d8c067a5255d522b455c60cd86 315 Gene3D G3DSA:3.40.50.1110 81 274 2.7E-23 T 29-03-2018 GBCGDNIH2_RS02225 8cf65c595f319a06d9e6d602488ac267 362 ProSitePatterns PS01348 MraY family signature 2. 191 202 - T 29-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 GBCGDNIH2_RS02225 8cf65c595f319a06d9e6d602488ac267 362 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 37 362 1.5E-125 T 29-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 GBCGDNIH2_RS02225 8cf65c595f319a06d9e6d602488ac267 362 Pfam PF00953 Glycosyl transferase family 4 101 286 9.6E-35 T 29-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 GBCGDNIH2_RS02225 8cf65c595f319a06d9e6d602488ac267 362 ProSitePatterns PS01347 MraY family signature 1. 70 82 - T 29-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 GBCGDNIH2_RS02225 8cf65c595f319a06d9e6d602488ac267 362 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 25 360 24.307 T 29-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 GBCGDNIH2_RS02225 8cf65c595f319a06d9e6d602488ac267 362 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 70 82 8.3E-6 T 29-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 GBCGDNIH2_RS05760 f0888aa2e0bdc0fa9ab77c48c58ba4b0 419 Pfam PF03743 Bacterial conjugation TrbI-like protein 234 411 6.3E-60 T 29-03-2018 IPR005498 Type IV secretion system, VirB10 / TraB / TrbI GBCGDNIH2_RS03450 9d248a04d725069640b2f7fa0b6c68c6 54 Pfam PF02069 Prokaryotic metallothionein 3 52 5.1E-18 T 29-03-2018 IPR000518 Metallothionein, family 14, prokaryote GO:0046872 GBCGDNIH2_RS03450 9d248a04d725069640b2f7fa0b6c68c6 54 Gene3D G3DSA:2.30.170.10 4 52 2.0E-16 T 29-03-2018 GBCGDNIH2_RS03450 9d248a04d725069640b2f7fa0b6c68c6 54 ProDom PD019076 METALLOTHIONEIN METALLOTHIONEIN ZINC METAL-BINDING CADMIUM CLUSTER MT METAL-THIOLATE COPPER SMTA 2 52 2.0E-8 T 29-03-2018 IPR000518 Metallothionein, family 14, prokaryote GO:0046872 GBCGDNIH2_RS03450 9d248a04d725069640b2f7fa0b6c68c6 54 SUPERFAMILY SSF57868 4 54 6.59E-14 T 29-03-2018 IPR017854 Metallothionein domain GO:0046872 GBCGDNIH2_RS03450 9d248a04d725069640b2f7fa0b6c68c6 54 PRINTS PR00859 Prokaryote metallothionein signature 19 35 7.6E-8 T 29-03-2018 IPR000518 Metallothionein, family 14, prokaryote GO:0046872 GBCGDNIH2_RS03450 9d248a04d725069640b2f7fa0b6c68c6 54 PRINTS PR00859 Prokaryote metallothionein signature 1 17 7.6E-8 T 29-03-2018 IPR000518 Metallothionein, family 14, prokaryote GO:0046872 GBCGDNIH2_RS02080 87a1000524f975278d5c55b854d356ca 170 Pfam PF04519 Polymer-forming cytoskeletal 42 137 7.6E-18 T 29-03-2018 IPR007607 Protein of unknown function DUF583 GBCGDNIH2_RS12305 3a353f8513de851842a5721aad390dd6 738 Gene3D G3DSA:1.20.1220.12 605 738 3.4E-43 T 29-03-2018 GBCGDNIH2_RS12305 3a353f8513de851842a5721aad390dd6 738 Gene3D G3DSA:3.20.20.360 232 602 4.8E-95 T 29-03-2018 GBCGDNIH2_RS12305 3a353f8513de851842a5721aad390dd6 738 Gene3D G3DSA:3.20.20.360 103 225 2.5E-18 T 29-03-2018 GBCGDNIH2_RS12305 3a353f8513de851842a5721aad390dd6 738 TIGRFAM TIGR01345 malate_syn_G: malate synthase G 14 737 0.0 T 29-03-2018 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 GBCGDNIH2_RS12305 3a353f8513de851842a5721aad390dd6 738 Hamap MF_00641 Malate synthase G [glcB]. 1 738 362.066 T 29-03-2018 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 GBCGDNIH2_RS12305 3a353f8513de851842a5721aad390dd6 738 SUPERFAMILY SSF51645 14 737 5.49E-275 T 29-03-2018 IPR011076 Malate synthase-like GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 GBCGDNIH2_RS12305 3a353f8513de851842a5721aad390dd6 738 Pfam PF01274 Malate synthase 24 700 3.8E-158 T 29-03-2018 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 GBCGDNIH2_RS12305 3a353f8513de851842a5721aad390dd6 738 Gene3D G3DSA:1.10.1860.10 8 102 7.5E-26 T 29-03-2018 GBCGDNIH2_RS05245 e7fc2a4cb4a64543925bbb6237b060a1 166 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 37 166 32.873 T 29-03-2018 IPR023035 Ribosomal protein S9, bacterial/plastid GBCGDNIH2_RS05245 e7fc2a4cb4a64543925bbb6237b060a1 166 SUPERFAMILY SSF54211 41 166 1.59E-48 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold GBCGDNIH2_RS05245 e7fc2a4cb4a64543925bbb6237b060a1 166 Gene3D G3DSA:3.30.230.10 39 166 1.2E-54 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup GBCGDNIH2_RS05245 e7fc2a4cb4a64543925bbb6237b060a1 166 Pfam PF00380 Ribosomal protein S9/S16 46 166 3.3E-48 T 29-03-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 GBCGDNIH2_RS05245 e7fc2a4cb4a64543925bbb6237b060a1 166 ProSitePatterns PS00360 Ribosomal protein S9 signature. 105 123 - T 29-03-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 GBCGDNIH2_RS10700 a90f5ef414e263c87e0a1727b6af3d71 82 Pfam PF11755 Protein of unknown function (DUF3311) 24 74 6.2E-20 T 29-03-2018 IPR021741 Protein of unknown function DUF3311 GBCGDNIH2_RS09820 e8bc6eee52f4297fb4a8301be8041a19 157 SUPERFAMILY SSF53098 16 154 1.09E-51 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 GBCGDNIH2_RS09820 e8bc6eee52f4297fb4a8301be8041a19 157 Hamap MF_00042 Ribonuclease H [rnhA]. 15 157 30.256 T 29-03-2018 IPR022892 Ribonuclease HI GO:0004523 GBCGDNIH2_RS09820 e8bc6eee52f4297fb4a8301be8041a19 157 Pfam PF00075 RNase H 18 153 8.3E-43 T 29-03-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 GBCGDNIH2_RS09820 e8bc6eee52f4297fb4a8301be8041a19 157 Gene3D G3DSA:3.30.420.10 11 156 4.0E-45 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 GBCGDNIH2_RS06525 6ea45d947e1a6abf5686e743a9910749 179 Gene3D G3DSA:1.10.10.10 8 99 1.2E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS06525 6ea45d947e1a6abf5686e743a9910749 179 Pfam PF01475 Ferric uptake regulator family 29 146 4.1E-16 T 29-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 GBCGDNIH2_RS06525 6ea45d947e1a6abf5686e743a9910749 179 SUPERFAMILY SSF46785 24 153 2.52E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS06415 9206df83c706f0cc776c0738bf4889a0 147 Gene3D G3DSA:1.10.238.10 103 139 0.17 T 29-03-2018 GBCGDNIH2_RS06415 9206df83c706f0cc776c0738bf4889a0 147 Gene3D G3DSA:1.10.238.10 44 102 0.0029 T 29-03-2018 GBCGDNIH2_RS10300 bce012c1836318d8355b9d781292f9e8 240 Pfam PF10615 Protein of unknown function (DUF2470) 165 236 4.7E-10 T 29-03-2018 IPR019595 Domain of unknown function DUF2470 GBCGDNIH2_RS10300 bce012c1836318d8355b9d781292f9e8 240 Gene3D G3DSA:3.20.180.10 167 240 6.6E-17 T 29-03-2018 IPR019595 Domain of unknown function DUF2470 GBCGDNIH2_RS10300 bce012c1836318d8355b9d781292f9e8 240 SUPERFAMILY SSF50475 13 239 9.35E-42 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 GBCGDNIH2_RS10300 bce012c1836318d8355b9d781292f9e8 240 Gene3D G3DSA:2.30.110.10 5 166 1.1E-33 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 GBCGDNIH2_RS10300 bce012c1836318d8355b9d781292f9e8 240 Pfam PF13883 Pyridoxamine 5'-phosphate oxidase 7 143 1.6E-8 T 29-03-2018 GBCGDNIH2_RS12340 a38bb6186b88e219fd27a77088afe724 630 Pfam PF04183 IucA / IucC family 177 418 7.5E-60 T 29-03-2018 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0015343|GO:0019290 GBCGDNIH2_RS12340 a38bb6186b88e219fd27a77088afe724 630 Pfam PF06276 Ferric iron reductase FhuF-like transporter 451 610 2.6E-23 T 29-03-2018 IPR022770 Ferric iron reductase FhuF domain GBCGDNIH2_RS07885 0f918508ed601caca59fad33df1485ce 252 SUPERFAMILY SSF52540 6 243 1.05E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS07885 0f918508ed601caca59fad33df1485ce 252 Pfam PF00005 ABC transporter 23 174 5.0E-23 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GBCGDNIH2_RS07885 0f918508ed601caca59fad33df1485ce 252 Gene3D G3DSA:3.40.50.300 1 250 7.5E-44 T 29-03-2018 GBCGDNIH2_RS07885 0f918508ed601caca59fad33df1485ce 252 SMART SM00382 32 223 1.2E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS09505 716d101291bd3585ca9b8df4caf65a4b 383 Gene3D G3DSA:3.90.226.10 27 366 1.6E-89 T 29-03-2018 GBCGDNIH2_RS09505 716d101291bd3585ca9b8df4caf65a4b 383 Pfam PF16113 Enoyl-CoA hydratase/isomerase 56 371 5.2E-102 T 29-03-2018 IPR032259 Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type GO:0003860 Reactome: R-HSA-70895 GBCGDNIH2_RS09505 716d101291bd3585ca9b8df4caf65a4b 383 SUPERFAMILY SSF52096 45 228 1.17E-70 T 29-03-2018 IPR029045 ClpP/crotonase-like domain GBCGDNIH2_RS09505 716d101291bd3585ca9b8df4caf65a4b 383 SUPERFAMILY SSF52096 282 357 1.17E-70 T 29-03-2018 IPR029045 ClpP/crotonase-like domain GBCGDNIH2_RS02775 c38416a3eef7fcc70399ed5a4be83e08 535 SUPERFAMILY SSF51905 293 432 8.76E-59 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS02775 c38416a3eef7fcc70399ed5a4be83e08 535 SUPERFAMILY SSF51905 1 196 8.76E-59 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS02775 c38416a3eef7fcc70399ed5a4be83e08 535 Pfam PF13450 NAD(P)-binding Rossmann-like domain 7 48 3.2E-7 T 29-03-2018 GBCGDNIH2_RS02775 c38416a3eef7fcc70399ed5a4be83e08 535 Gene3D G3DSA:3.50.50.60 1 370 5.6E-53 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GBCGDNIH2_RS02775 c38416a3eef7fcc70399ed5a4be83e08 535 SUPERFAMILY SSF54862 434 532 1.12E-25 T 29-03-2018 GBCGDNIH2_RS02775 c38416a3eef7fcc70399ed5a4be83e08 535 Pfam PF05187 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S 430 531 2.2E-47 T 29-03-2018 GBCGDNIH2_RS02775 c38416a3eef7fcc70399ed5a4be83e08 535 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 165 180 1.6E-6 T 29-03-2018 GBCGDNIH2_RS02775 c38416a3eef7fcc70399ed5a4be83e08 535 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 1.6E-6 T 29-03-2018 GBCGDNIH2_RS02775 c38416a3eef7fcc70399ed5a4be83e08 535 SUPERFAMILY SSF54373 197 293 3.77E-35 T 29-03-2018 GBCGDNIH2_RS10415 806e9d3eb27d3f1f0fd0a2eab9dc9a46 295 Gene3D G3DSA:3.40.190.10 105 182 1.3E-22 T 29-03-2018 GBCGDNIH2_RS10415 806e9d3eb27d3f1f0fd0a2eab9dc9a46 295 SUPERFAMILY SSF53850 17 197 2.5E-53 T 29-03-2018 GBCGDNIH2_RS10415 806e9d3eb27d3f1f0fd0a2eab9dc9a46 295 Gene3D G3DSA:3.40.190.10 14 104 9.0E-26 T 29-03-2018 GBCGDNIH2_RS10415 806e9d3eb27d3f1f0fd0a2eab9dc9a46 295 Gene3D G3DSA:3.30.70.260 196 291 3.6E-20 T 29-03-2018 GBCGDNIH2_RS10415 806e9d3eb27d3f1f0fd0a2eab9dc9a46 295 PIRSF PIRSF001500 11 287 3.1E-56 T 29-03-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 GBCGDNIH2_RS10415 806e9d3eb27d3f1f0fd0a2eab9dc9a46 295 SUPERFAMILY SSF55021 196 284 1.68E-21 T 29-03-2018 GBCGDNIH2_RS10415 806e9d3eb27d3f1f0fd0a2eab9dc9a46 295 Pfam PF00800 Prephenate dehydratase 17 191 1.2E-46 T 29-03-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 GBCGDNIH2_RS07720 d609b541c6a0b070556f8795a4ab71a6 276 SUPERFAMILY SSF55166 27 267 7.14E-76 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 GBCGDNIH2_RS07720 d609b541c6a0b070556f8795a4ab71a6 276 Gene3D G3DSA:3.30.1380.10 20 269 1.6E-75 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 GBCGDNIH2_RS07720 d609b541c6a0b070556f8795a4ab71a6 276 Pfam PF03411 Penicillin-insensitive murein endopeptidase 33 264 1.3E-84 T 29-03-2018 IPR005073 Peptidase M74, penicillin-insensitive murein endopeptidase GO:0004252|GO:0006508|GO:0030288 GBCGDNIH2_RS09600 322243de39af18e874d4f862cd089172 381 Pfam PF02653 Branched-chain amino acid transport system / permease component 35 333 4.4E-35 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 GBCGDNIH2_RS09600 322243de39af18e874d4f862cd089172 381 Gene3D G3DSA:1.10.3470.10 11 339 2.3E-28 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like GBCGDNIH2_RS09600 322243de39af18e874d4f862cd089172 381 TIGRFAM TIGR03408 urea_trans_UrtC: urea ABC transporter, permease protein UrtC 27 344 1.7E-132 T 29-03-2018 IPR017778 ABC transporter, urea, permease protein, UrtC GBCGDNIH2_RS08375 49c4785712005597d912cc0cae7224e9 413 Pfam PF06381 Protein of unknown function (DUF1073) 33 392 8.4E-101 T 29-03-2018 IPR024459 Protein of unknown function DUF1073 GBCGDNIH2_RS00625 0154a6171537e40405c6bf85c2af107e 291 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 13 47 7.7E-7 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain GBCGDNIH2_RS00625 0154a6171537e40405c6bf85c2af107e 291 Gene3D G3DSA:1.10.3720.10 7 274 1.6E-32 T 29-03-2018 GBCGDNIH2_RS00625 0154a6171537e40405c6bf85c2af107e 291 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 275 8.9E-17 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GBCGDNIH2_RS00625 0154a6171537e40405c6bf85c2af107e 291 SUPERFAMILY SSF161098 94 267 1.24E-16 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GBCGDNIH2_RS07325 55bcbe5ceb485a7e20e94b9d2b37a064 64 Pfam PF01679 Proteolipid membrane potential modulator 1 47 3.5E-7 T 29-03-2018 IPR000612 Proteolipid membrane potential modulator GO:0016021 GBCGDNIH2_RS09655 3fa62fe215b56cdef03286f5cd5708f4 287 Pfam PF12787 EcsC protein family 73 253 2.0E-27 T 29-03-2018 IPR024787 EcsC protein GBCGDNIH2_RS00580 2a7eaaa3cc2297e186dc46f00d93d671 315 Gene3D G3DSA:3.20.20.190 33 309 8.8E-44 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 GBCGDNIH2_RS00580 2a7eaaa3cc2297e186dc46f00d93d671 315 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 37 293 1.0E-17 T 29-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 GBCGDNIH2_RS00580 2a7eaaa3cc2297e186dc46f00d93d671 315 SUPERFAMILY SSF51695 30 298 8.11E-49 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 GBCGDNIH2_RS05145 41c3e3eed7d9787ee003436b0f92857a 286 Pfam PF06230 Protein of unknown function (DUF1009) 63 274 2.5E-69 T 29-03-2018 IPR010415 Protein of unknown function DUF1009 GBCGDNIH2_RS08865 1d70cd4c071ec15ed542f31563b234fa 266 Gene3D G3DSA:2.40.160.20 7 245 4.7E-6 T 29-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 GBCGDNIH2_RS11330 552bccbe478577f261d964943b40b124 251 Pfam PF09335 SNARE associated Golgi protein 72 191 8.6E-19 T 29-03-2018 IPR032816 SNARE associated Golgi protein GBCGDNIH2_RS04610 adc0f40800cb7c862c14e19481a1dabf 177 SUPERFAMILY SSF53254 1 154 3.43E-22 T 29-03-2018 IPR029033 Histidine phosphatase superfamily GBCGDNIH2_RS04610 adc0f40800cb7c862c14e19481a1dabf 177 Gene3D G3DSA:3.40.50.1240 1 169 1.7E-26 T 29-03-2018 IPR029033 Histidine phosphatase superfamily GBCGDNIH2_RS04610 adc0f40800cb7c862c14e19481a1dabf 177 SMART SM00855 3 93 2.8E-6 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 GBCGDNIH2_RS04610 adc0f40800cb7c862c14e19481a1dabf 177 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 67 1.7E-7 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 GBCGDNIH2_RS11630 cfda859c196da989dcf0930648ad788a 422 Gene3D G3DSA:3.40.50.2000 26 405 1.4E-11 T 29-03-2018 GBCGDNIH2_RS11630 cfda859c196da989dcf0930648ad788a 422 Pfam PF04413 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) 37 216 1.6E-53 T 29-03-2018 IPR007507 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675 GBCGDNIH2_RS06820 5ea3e462e408ab4df53f67cb64019f95 475 Pfam PF02321 Outer membrane efflux protein 276 448 2.4E-12 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 GBCGDNIH2_RS06820 5ea3e462e408ab4df53f67cb64019f95 475 SUPERFAMILY SSF56954 81 450 3.01E-36 T 29-03-2018 GBCGDNIH2_RS06820 5ea3e462e408ab4df53f67cb64019f95 475 Gene3D G3DSA:1.20.1600.10 39 451 3.4E-33 T 29-03-2018 GBCGDNIH2_RS02690 6b33ab87e72a00fd05e71fc81b84b00a 276 Gene3D G3DSA:2.40.70.10 1 210 5.6E-5 T 29-03-2018 IPR021109 Aspartic peptidase domain GBCGDNIH2_RS02690 6b33ab87e72a00fd05e71fc81b84b00a 276 SUPERFAMILY SSF50630 2 274 5.63E-12 T 29-03-2018 IPR021109 Aspartic peptidase domain GBCGDNIH2_RS09575 b797bd95b73df6a329e3fd4215cfda95 352 Pfam PF11927 Protein of unknown function (DUF3445) 55 293 1.2E-50 T 29-03-2018 IPR021848 Protein of unknown function DUF3445 GBCGDNIH2_RS12115 5e249cc47cc78332b2a564e3fe66dabc 236 SUPERFAMILY SSF51419 3 215 3.74E-64 T 29-03-2018 IPR029066 PLP-binding barrel GBCGDNIH2_RS12115 5e249cc47cc78332b2a564e3fe66dabc 236 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 4 217 2.6E-47 T 29-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein GBCGDNIH2_RS12115 5e249cc47cc78332b2a564e3fe66dabc 236 Gene3D G3DSA:3.20.20.10 1 225 5.9E-55 T 29-03-2018 IPR029066 PLP-binding barrel GBCGDNIH2_RS12115 5e249cc47cc78332b2a564e3fe66dabc 236 Pfam PF01168 Alanine racemase, N-terminal domain 5 218 2.6E-23 T 29-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 GBCGDNIH2_RS12115 5e249cc47cc78332b2a564e3fe66dabc 236 PIRSF PIRSF004848 1 223 1.4E-54 T 29-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein GBCGDNIH2_RS05825 ee61994a788bb07cffe7345d8fd4ce7f 342 SMART SM00382 31 193 0.0032 T 29-03-2018 IPR003593 AAA+ ATPase domain GBCGDNIH2_RS05825 ee61994a788bb07cffe7345d8fd4ce7f 342 SUPERFAMILY SSF52540 11 233 1.25E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS05825 ee61994a788bb07cffe7345d8fd4ce7f 342 Gene3D G3DSA:1.10.8.60 181 243 1.2E-5 T 29-03-2018 GBCGDNIH2_RS05825 ee61994a788bb07cffe7345d8fd4ce7f 342 Gene3D G3DSA:3.40.50.300 15 180 4.2E-31 T 29-03-2018 GBCGDNIH2_RS05825 ee61994a788bb07cffe7345d8fd4ce7f 342 Pfam PF13177 DNA polymerase III, delta subunit 15 193 5.1E-37 T 29-03-2018 GBCGDNIH2_RS08330 1cebd7df559722194b08bf164a8d979c 148 Pfam PF11681 Protein of unknown function (DUF3277) 30 137 1.3E-9 T 29-03-2018 IPR021695 Bacteriophage rv5, Orf52 GBCGDNIH2_RS10105 3a19f790d646603215ce91d992f0a51a 109 Pfam PF11390 NADH-dependant formate dehydrogenase delta subunit FdsD 1 55 1.4E-19 T 29-03-2018 IPR021074 Formate dehydrogenase, delta subunit GBCGDNIH2_RS01415 6a50334ce1e992fbbbbabdae34cb6a65 112 Pfam PF02325 YGGT family 17 91 2.6E-19 T 29-03-2018 IPR003425 CCB3/YggT GO:0016020 GBCGDNIH2_RS06460 c27f45f579b98dfb8b4158ba5c583b3a 158 Pfam PF11026 Protein of unknown function (DUF2721) 21 147 5.2E-29 T 29-03-2018 IPR021279 Protein of unknown function DUF2721 GBCGDNIH2_RS00970 a5152d6de08fcb0f3946adaee719936a 183 Gene3D G3DSA:3.40.630.30 7 182 5.1E-30 T 29-03-2018 GBCGDNIH2_RS00970 a5152d6de08fcb0f3946adaee719936a 183 Pfam PF13420 Acetyltransferase (GNAT) domain 9 161 1.9E-22 T 29-03-2018 GBCGDNIH2_RS00970 a5152d6de08fcb0f3946adaee719936a 183 SUPERFAMILY SSF55729 8 171 1.05E-27 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase GBCGDNIH2_RS02040 428f62db12d8cbc6d42af78f154590f6 138 Pfam PF07475 HPr Serine kinase C-terminal domain 10 65 2.4E-12 T 29-03-2018 IPR011104 HPr kinase/phosphorylase, C-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 GBCGDNIH2_RS02040 428f62db12d8cbc6d42af78f154590f6 138 Gene3D G3DSA:3.40.50.300 2 130 6.9E-15 T 29-03-2018 GBCGDNIH2_RS02040 428f62db12d8cbc6d42af78f154590f6 138 SUPERFAMILY SSF53795 8 89 4.27E-14 T 29-03-2018 GBCGDNIH2_RS07735 7cfd40e6ab3e44264971736b2445ba5f 380 SUPERFAMILY SSF52091 21 101 3.14E-5 T 29-03-2018 IPR002645 STAS domain GBCGDNIH2_RS07735 7cfd40e6ab3e44264971736b2445ba5f 380 Pfam PF02405 Permease MlaE 164 373 2.2E-59 T 29-03-2018 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 GBCGDNIH2_RS04425 d94a02d4143afb72bce94ce4d1354909 183 Gene3D G3DSA:1.10.357.10 60 182 2.7E-16 T 29-03-2018 GBCGDNIH2_RS04425 d94a02d4143afb72bce94ce4d1354909 183 Gene3D G3DSA:1.10.260.40 37 59 0.0069 T 29-03-2018 GBCGDNIH2_RS04425 d94a02d4143afb72bce94ce4d1354909 183 SUPERFAMILY SSF48498 77 181 1.51E-15 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal GBCGDNIH2_RS04425 d94a02d4143afb72bce94ce4d1354909 183 Gene3D G3DSA:1.10.10.60 2 36 1.0E-10 T 29-03-2018 GBCGDNIH2_RS04425 d94a02d4143afb72bce94ce4d1354909 183 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 56 3.4E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GBCGDNIH2_RS04425 d94a02d4143afb72bce94ce4d1354909 183 SUPERFAMILY SSF46689 8 71 9.23E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 GBCGDNIH2_RS09080 6bd64efcf583c43e181bc66092f33c59 444 Pfam PF00982 Glycosyltransferase family 20 20 441 5.9E-119 T 29-03-2018 IPR001830 Glycosyl transferase, family 20 GO:0003824|GO:0005992 GBCGDNIH2_RS09080 6bd64efcf583c43e181bc66092f33c59 444 SUPERFAMILY SSF53756 2 441 8.16E-138 T 29-03-2018 GBCGDNIH2_RS09080 6bd64efcf583c43e181bc66092f33c59 444 Gene3D G3DSA:3.40.50.2000 233 425 7.7E-42 T 29-03-2018 GBCGDNIH2_RS09080 6bd64efcf583c43e181bc66092f33c59 444 Gene3D G3DSA:3.40.50.2000 1 232 4.9E-53 T 29-03-2018 GBCGDNIH2_RS05790 b994ac751ad46085d1f47070afba2375 336 Pfam PF09982 Uncharacterized protein conserved in bacteria (DUF2219) 45 334 9.5E-90 T 29-03-2018 IPR018707 Protein of unknown function DUF2219 GBCGDNIH2_RS05790 b994ac751ad46085d1f47070afba2375 336 Gene3D G3DSA:2.40.128.140 30 333 1.4E-90 T 29-03-2018 IPR018707 Protein of unknown function DUF2219 GBCGDNIH2_RS11365 1a18528a9a5c2def988cd39fb9607034 212 Gene3D G3DSA:3.40.50.150 12 206 1.2E-21 T 29-03-2018 GBCGDNIH2_RS11365 1a18528a9a5c2def988cd39fb9607034 212 SUPERFAMILY SSF53335 41 169 5.63E-21 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GBCGDNIH2_RS11365 1a18528a9a5c2def988cd39fb9607034 212 Pfam PF05175 Methyltransferase small domain 57 142 1.3E-6 T 29-03-2018 IPR007848 Methyltransferase small domain GO:0008168 GBCGDNIH2_RS01215 c39d3904b85b91711d2498a33e62e7d0 83 SUPERFAMILY SSF47336 9 80 8.11E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain GBCGDNIH2_RS01215 c39d3904b85b91711d2498a33e62e7d0 83 Gene3D G3DSA:1.10.1200.10 5 82 2.4E-14 T 29-03-2018 GBCGDNIH2_RS01215 c39d3904b85b91711d2498a33e62e7d0 83 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 37 76 0.007 T 29-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 GBCGDNIH2_RS01215 c39d3904b85b91711d2498a33e62e7d0 83 Pfam PF00550 Phosphopantetheine attachment site 34 76 1.6E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain GBCGDNIH2_RS02555 c98a0995673bb60c62e76eab9a0865a1 382 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 233 242 - T 29-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 GBCGDNIH2_RS02555 c98a0995673bb60c62e76eab9a0865a1 382 Gene3D G3DSA:3.90.1150.10 281 381 1.9E-13 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 GBCGDNIH2_RS02555 c98a0995673bb60c62e76eab9a0865a1 382 Gene3D G3DSA:3.40.640.10 50 280 4.7E-48 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GBCGDNIH2_RS02555 c98a0995673bb60c62e76eab9a0865a1 382 SUPERFAMILY SSF53383 10 377 3.58E-88 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase GBCGDNIH2_RS02555 c98a0995673bb60c62e76eab9a0865a1 382 Pfam PF00155 Aminotransferase class I and II 42 371 6.2E-49 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 GBCGDNIH2_RS07745 9f43bace4aba2c4e44e30b46fe9809c1 323 Pfam PF02470 MlaD protein 45 135 1.6E-12 T 29-03-2018 IPR003399 Mce/MlaD GBCGDNIH2_RS12505 8192ed526b7346c6a4a28110a197ca32 124 Gene3D G3DSA:3.30.70.1100 16 115 4.0E-6 T 29-03-2018 GBCGDNIH2_RS12505 8192ed526b7346c6a4a28110a197ca32 124 Pfam PF17074 Darcynin, domain of unknown function 1 124 1.7E-76 T 29-03-2018 IPR031409 Darcynin GBCGDNIH2_RS12505 8192ed526b7346c6a4a28110a197ca32 124 ProDom PD888784 DARCYNIN HOMOLOG 48 113 1.0E-19 T 29-03-2018 GBCGDNIH2_RS06375 728e69aa80ab1e98764c7de33e15f32d 109 Pfam PF04977 Septum formation initiator 23 104 2.3E-7 T 29-03-2018 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 GBCGDNIH2_RS08605 9f1893bfb7ff157f1ed62d50b902d358 218 Pfam PF00293 NUDIX domain 47 154 2.2E-16 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 GBCGDNIH2_RS08605 9f1893bfb7ff157f1ed62d50b902d358 218 SUPERFAMILY SSF55811 45 198 1.3E-33 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 GBCGDNIH2_RS08605 9f1893bfb7ff157f1ed62d50b902d358 218 Gene3D G3DSA:3.90.79.10 30 204 6.1E-37 T 29-03-2018 GBCGDNIH2_RS11500 47b8c795013d001489f968bfe3bed722 259 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 15 257 1.6E-77 T 29-03-2018 IPR003453 ABC transport permease subunit MlaE, Proteobacteria GBCGDNIH2_RS11500 47b8c795013d001489f968bfe3bed722 259 Pfam PF02405 Permease MlaE 45 254 9.7E-79 T 29-03-2018 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 GBCGDNIH2_RS05035 770c97ac66c2c3299def323324bc6aa4 101 Gene3D G3DSA:3.30.160.190 1 78 4.3E-27 T 29-03-2018 GBCGDNIH2_RS05035 770c97ac66c2c3299def323324bc6aa4 101 Pfam PF04800 ETC complex I subunit conserved region 2 95 2.7E-30 T 29-03-2018 IPR006885 NADH dehydrogenase ubiquinone Fe-S protein 4, mitochondrial GO:0016651|GO:0022900 GBCGDNIH2_RS08590 1fee9d30edbd5388572164717058fd28 248 Pfam PF01988 VIT family 19 240 3.4E-54 T 29-03-2018 IPR008217 Ccc1 family GBCGDNIH2_RS08180 cbe13c26e9392e1fe1404bb3e2cc12c4 212 SUPERFAMILY SSF48498 94 208 2.88E-26 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal GBCGDNIH2_RS08180 cbe13c26e9392e1fe1404bb3e2cc12c4 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 73 1.7E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GBCGDNIH2_RS08180 cbe13c26e9392e1fe1404bb3e2cc12c4 212 Gene3D G3DSA:1.10.357.10 75 208 5.9E-22 T 29-03-2018 GBCGDNIH2_RS08180 cbe13c26e9392e1fe1404bb3e2cc12c4 212 SUPERFAMILY SSF46689 17 91 3.54E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 GBCGDNIH2_RS08180 cbe13c26e9392e1fe1404bb3e2cc12c4 212 Gene3D G3DSA:1.10.10.60 14 74 4.3E-14 T 29-03-2018 GBCGDNIH2_RS10675 1595d6fb98e222c7978d3b39c8f20fe0 271 Pfam PF04366 Las17-binding protein actin regulator 101 222 1.5E-28 T 29-03-2018 IPR007461 Ysc84 actin-binding domain GBCGDNIH2_RS04890 09d517762397a6e36d336cd6eb56f4d3 136 Gene3D G3DSA:1.20.120.330 12 133 1.1E-7 T 29-03-2018 GBCGDNIH2_RS03695 987789ad7d5d2c0606c3f7949130a075 211 Pfam PF09335 SNARE associated Golgi protein 42 163 2.9E-15 T 29-03-2018 IPR032816 SNARE associated Golgi protein GBCGDNIH2_RS08740 adebbc9315b0ede5bdc5c31c06f360e1 240 Pfam PF05742 Transport and Golgi organisation 2 1 170 1.6E-22 T 29-03-2018 IPR008551 Transport and Golgi organisation protein 2 GBCGDNIH2_RS08740 adebbc9315b0ede5bdc5c31c06f360e1 240 Gene3D G3DSA:3.60.60.10 1 152 3.4E-6 T 29-03-2018 GBCGDNIH2_RS11710 c9641c5cf7dbc642389ec384ada2d454 236 Pfam PF08241 Methyltransferase domain 76 172 1.6E-21 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 GBCGDNIH2_RS11710 c9641c5cf7dbc642389ec384ada2d454 236 Gene3D G3DSA:3.40.50.150 2 226 5.6E-34 T 29-03-2018 GBCGDNIH2_RS11710 c9641c5cf7dbc642389ec384ada2d454 236 SUPERFAMILY SSF53335 37 210 3.22E-36 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GBCGDNIH2_RS02075 4d8f4fc5e2c39e0c607eb9daa55d02e9 242 Pfam PF07264 Etoposide-induced protein 2.4 (EI24) 19 221 9.8E-21 T 29-03-2018 GBCGDNIH2_RS01580 4d7121980182e6f770c8e4e1018ee098 128 Gene3D G3DSA:1.10.260.40 49 128 3.1E-4 T 29-03-2018 GBCGDNIH2_RS03205 c91c4f4737c0e7a3286b73f098a79240 111 Gene3D G3DSA:3.30.300.90 9 110 3.9E-24 T 29-03-2018 GBCGDNIH2_RS03205 c91c4f4737c0e7a3286b73f098a79240 111 PIRSF PIRSF003113 1 111 3.8E-26 T 29-03-2018 IPR002634 BolA protein GBCGDNIH2_RS03205 c91c4f4737c0e7a3286b73f098a79240 111 Pfam PF01722 BolA-like protein 20 104 3.6E-26 T 29-03-2018 IPR002634 BolA protein GBCGDNIH2_RS03205 c91c4f4737c0e7a3286b73f098a79240 111 SUPERFAMILY SSF82657 7 108 3.01E-23 T 29-03-2018 IPR002634 BolA protein GBCGDNIH2_RS11265 f96fc6e62f64144226ff82dc9aae761b 429 Pfam PF02646 RmuC family 123 404 2.2E-54 T 29-03-2018 IPR003798 DNA recombination RmuC GBCGDNIH2_RS11265 f96fc6e62f64144226ff82dc9aae761b 429 Gene3D G3DSA:1.20.5.1230 40 401 3.3E-8 T 29-03-2018 GBCGDNIH2_RS09300 ab1962175e0dd05afb6c30571cf67785 259 SUPERFAMILY SSF53335 8 209 7.17E-40 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GBCGDNIH2_RS09300 ab1962175e0dd05afb6c30571cf67785 259 Pfam PF13649 Methyltransferase domain 44 133 1.3E-19 T 29-03-2018 GBCGDNIH2_RS09300 ab1962175e0dd05afb6c30571cf67785 259 Gene3D G3DSA:3.40.50.150 2 242 5.0E-36 T 29-03-2018 GBCGDNIH2_RS06245 f2a62abd8ec618b55c4629c0c1dbab29 256 SUPERFAMILY SSF56281 11 245 8.39E-31 T 29-03-2018 IPR001279 Metallo-beta-lactamase GBCGDNIH2_RS06245 f2a62abd8ec618b55c4629c0c1dbab29 256 Pfam PF00753 Metallo-beta-lactamase superfamily 26 240 5.5E-26 T 29-03-2018 IPR001279 Metallo-beta-lactamase GBCGDNIH2_RS06245 f2a62abd8ec618b55c4629c0c1dbab29 256 Gene3D G3DSA:3.60.15.10 2 255 4.9E-34 T 29-03-2018 IPR001279 Metallo-beta-lactamase GBCGDNIH2_RS06245 f2a62abd8ec618b55c4629c0c1dbab29 256 SMART SM00849 27 240 7.8E-21 T 29-03-2018 IPR001279 Metallo-beta-lactamase GBCGDNIH2_RS08690 47c637c8cc3e9afd4856ef3dee577c14 125 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 35 120 29.027 T 29-03-2018 IPR022935 ATP-dependent Clp protease adaptor protein ClpS GBCGDNIH2_RS08690 47c637c8cc3e9afd4856ef3dee577c14 125 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 43 121 1.3E-35 T 29-03-2018 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 GBCGDNIH2_RS08690 47c637c8cc3e9afd4856ef3dee577c14 125 SUPERFAMILY SSF54736 41 124 1.94E-32 T 29-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like GBCGDNIH2_RS08690 47c637c8cc3e9afd4856ef3dee577c14 125 Gene3D G3DSA:3.30.1390.10 33 124 3.2E-36 T 29-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like GBCGDNIH2_RS11325 c291932c46f1be4656f56d1314c4fd9d 86 Pfam PF06233 Usg-like family 6 81 3.0E-39 T 29-03-2018 IPR009354 Usg-like GBCGDNIH2_RS09765 5e72c86de7e900244d8e8eadcf7a353f 136 Pfam PF09527 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter 63 115 6.2E-15 T 29-03-2018 IPR032820 Putative F0F1-ATPase subunit, Ca2+/Mg2+ transporter GBCGDNIH2_RS00135 7c99bd9666d9e79be52d405b1deff589 199 SUPERFAMILY SSF55469 10 196 5.76E-46 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 GBCGDNIH2_RS00135 7c99bd9666d9e79be52d405b1deff589 199 Gene3D G3DSA:3.40.109.10 1 199 2.6E-37 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 GBCGDNIH2_RS00135 7c99bd9666d9e79be52d405b1deff589 199 Pfam PF00881 Nitroreductase family 78 164 6.8E-6 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 GBCGDNIH2_RS00135 7c99bd9666d9e79be52d405b1deff589 199 Pfam PF00881 Nitroreductase family 19 60 4.1E-12 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 GBCGDNIH2_RS06890 88c6a3e607ab9ff56b449e39e3e22c05 90 Pfam PF07330 Protein of unknown function (DUF1467) 6 81 5.7E-23 T 29-03-2018 IPR009935 Protein of unknown function DUF1467 GBCGDNIH2_RS09265 6a38cd8727cd665dd1383cef29d4360a 134 Pfam PF01464 Transglycosylase SLT domain 13 114 1.0E-8 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 GBCGDNIH2_RS09265 6a38cd8727cd665dd1383cef29d4360a 134 SUPERFAMILY SSF53955 6 123 3.26E-26 T 29-03-2018 IPR023346 Lysozyme-like domain GBCGDNIH2_RS09265 6a38cd8727cd665dd1383cef29d4360a 134 Gene3D G3DSA:1.10.530.10 4 130 2.9E-13 T 29-03-2018 GBCGDNIH2_RS11270 d2b1a98c8108ec58f657e1a03e85cb4a 410 Gene3D G3DSA:1.20.1250.20 218 407 3.5E-15 T 29-03-2018 GBCGDNIH2_RS11270 d2b1a98c8108ec58f657e1a03e85cb4a 410 SUPERFAMILY SSF103473 2 403 3.14E-52 T 29-03-2018 IPR020846 Major facilitator superfamily domain GBCGDNIH2_RS11270 d2b1a98c8108ec58f657e1a03e85cb4a 410 Pfam PF07690 Major Facilitator Superfamily 36 331 6.3E-20 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 GBCGDNIH2_RS11270 d2b1a98c8108ec58f657e1a03e85cb4a 410 Gene3D G3DSA:1.20.1250.20 28 213 2.8E-18 T 29-03-2018 GBCGDNIH2_RS00230 5adf7e8ce8da61650551aa637ae74a7e 206 Gene3D G3DSA:2.40.440.10 14 162 2.5E-5 T 29-03-2018 GBCGDNIH2_RS00230 5adf7e8ce8da61650551aa637ae74a7e 206 SUPERFAMILY SSF141523 109 151 3.92E-5 T 29-03-2018 GBCGDNIH2_RS00230 5adf7e8ce8da61650551aa637ae74a7e 206 SUPERFAMILY SSF141523 19 81 3.92E-5 T 29-03-2018 GBCGDNIH2_RS03325 f51cf6762f50d248f66b6eaa629e925f 335 Pfam PF03186 CobD/Cbib protein 20 312 1.1E-87 T 29-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 GBCGDNIH2_RS03325 f51cf6762f50d248f66b6eaa629e925f 335 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 17 314 1.3E-60 T 29-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 GBCGDNIH2_RS03325 f51cf6762f50d248f66b6eaa629e925f 335 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 335 95.205 T 29-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 GBCGDNIH2_RS04520 447c69178a32548db6559d93c2cd7b50 220 SUPERFAMILY SSF64288 40 199 5.65E-21 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain GBCGDNIH2_RS04520 447c69178a32548db6559d93c2cd7b50 220 Gene3D G3DSA:3.40.1410.10 36 212 3.6E-23 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain GBCGDNIH2_RS05675 2626b88513890bc215506919ea893068 338 SUPERFAMILY SSF50129 3 121 1.1E-33 T 29-03-2018 IPR011032 GroES-like GBCGDNIH2_RS05675 2626b88513890bc215506919ea893068 338 SUPERFAMILY SSF50129 160 169 1.1E-33 T 29-03-2018 IPR011032 GroES-like GBCGDNIH2_RS05675 2626b88513890bc215506919ea893068 338 Pfam PF00107 Zinc-binding dehydrogenase 172 260 7.8E-12 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 GBCGDNIH2_RS05675 2626b88513890bc215506919ea893068 338 Gene3D G3DSA:3.40.50.720 171 305 3.3E-15 T 29-03-2018 GBCGDNIH2_RS05675 2626b88513890bc215506919ea893068 338 SMART SM00829 14 335 2.9E-9 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 GBCGDNIH2_RS05675 2626b88513890bc215506919ea893068 338 Gene3D G3DSA:3.90.180.10 1 170 1.2E-39 T 29-03-2018 GBCGDNIH2_RS05675 2626b88513890bc215506919ea893068 338 SUPERFAMILY SSF51735 123 266 1.71E-24 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS05675 2626b88513890bc215506919ea893068 338 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 30 92 6.6E-9 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 GBCGDNIH2_RS03620 23ead46a6be5b643cf3362d8b252174d 510 Pfam PF00361 Proton-conducting membrane transporter 137 424 4.4E-67 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS03620 23ead46a6be5b643cf3362d8b252174d 510 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 10 487 1.2E-160 T 29-03-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS03620 23ead46a6be5b643cf3362d8b252174d 510 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 382 408 2.0E-34 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS03620 23ead46a6be5b643cf3362d8b252174d 510 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 242 266 2.0E-34 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS03620 23ead46a6be5b643cf3362d8b252174d 510 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 173 197 2.0E-34 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS03620 23ead46a6be5b643cf3362d8b252174d 510 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 143 162 2.0E-34 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS03620 23ead46a6be5b643cf3362d8b252174d 510 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 330 349 2.0E-34 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GBCGDNIH2_RS12175 726c3b521f1c79cab5f608e598d1c9b9 481 Pfam PF04966 Carbohydrate-selective porin, OprB family 106 468 8.5E-44 T 29-03-2018 IPR007049 Carbohydrate-selective porin OprB GO:0005215|GO:0006810|GO:0016021 GBCGDNIH2_RS09295 5b844d433ba263f1f6a347fae2dcea51 143 SUPERFAMILY SSF46785 4 136 4.44E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS09295 5b844d433ba263f1f6a347fae2dcea51 143 Gene3D G3DSA:1.10.10.10 1 143 1.3E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS09295 5b844d433ba263f1f6a347fae2dcea51 143 Pfam PF02082 Transcriptional regulator 4 81 1.5E-21 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type GBCGDNIH2_RS01950 d75368557ae5c675492f0d79cbb52277 259 Pfam PF01323 DSBA-like thioredoxin domain 112 255 8.1E-23 T 29-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 GBCGDNIH2_RS01950 d75368557ae5c675492f0d79cbb52277 259 Gene3D G3DSA:3.40.30.10 87 259 1.6E-37 T 29-03-2018 GBCGDNIH2_RS01950 d75368557ae5c675492f0d79cbb52277 259 SUPERFAMILY SSF52833 89 254 3.0E-37 T 29-03-2018 IPR012336 Thioredoxin-like fold GBCGDNIH2_RS06425 1fac23a6cb6dd598ff321c7a38433e9d 163 Pfam PF02464 Competence-damaged protein 13 160 1.2E-55 T 29-03-2018 IPR008136 CinA, C-terminal GBCGDNIH2_RS06425 1fac23a6cb6dd598ff321c7a38433e9d 163 Gene3D G3DSA:3.90.950.20 1 163 9.3E-56 T 29-03-2018 GBCGDNIH2_RS06425 1fac23a6cb6dd598ff321c7a38433e9d 163 SUPERFAMILY SSF142433 7 160 8.5E-54 T 29-03-2018 IPR008136 CinA, C-terminal GBCGDNIH2_RS06425 1fac23a6cb6dd598ff321c7a38433e9d 163 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 17 158 1.3E-45 T 29-03-2018 IPR008136 CinA, C-terminal GBCGDNIH2_RS12010 865bd19dea0fb0f8b5d329548e0805df 132 Gene3D G3DSA:3.10.180.10 1 129 1.8E-14 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase GBCGDNIH2_RS12010 865bd19dea0fb0f8b5d329548e0805df 132 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2 118 2.5E-4 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain GBCGDNIH2_RS12010 865bd19dea0fb0f8b5d329548e0805df 132 SUPERFAMILY SSF54593 1 120 1.11E-18 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase GBCGDNIH2_RS03435 defb5d527af6e9bbf71d2027e362df91 277 SUPERFAMILY SSF53955 136 204 3.63E-12 T 29-03-2018 IPR023346 Lysozyme-like domain GBCGDNIH2_RS03435 defb5d527af6e9bbf71d2027e362df91 277 SUPERFAMILY SSF53955 57 108 3.63E-12 T 29-03-2018 IPR023346 Lysozyme-like domain GBCGDNIH2_RS03435 defb5d527af6e9bbf71d2027e362df91 277 Gene3D G3DSA:1.10.530.10 45 227 2.8E-14 T 29-03-2018 GBCGDNIH2_RS03435 defb5d527af6e9bbf71d2027e362df91 277 Pfam PF01464 Transglycosylase SLT domain 60 191 2.1E-5 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 GBCGDNIH2_RS04590 0a48d89b20373c0693ba243e2f5f9e08 211 Pfam PF09601 Protein of unknown function (DUF2459) 9 164 7.0E-21 T 29-03-2018 IPR011727 Conserved hypothetical protein CHP02117 GBCGDNIH2_RS12520 2e8318b97b1df63929a3855a72e11ef9 253 Gene3D G3DSA:3.90.550.10 2 237 2.1E-27 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS12520 2e8318b97b1df63929a3855a72e11ef9 253 SUPERFAMILY SSF53448 9 206 3.38E-32 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS12520 2e8318b97b1df63929a3855a72e11ef9 253 Pfam PF00535 Glycosyl transferase family 2 12 136 1.1E-22 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 GBCGDNIH2_RS06255 d4c76b060d17657b6b0de3f3a881a7e0 186 SUPERFAMILY SSF55729 18 176 1.04E-36 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase GBCGDNIH2_RS06255 d4c76b060d17657b6b0de3f3a881a7e0 186 Pfam PF13302 Acetyltransferase (GNAT) domain 19 152 1.2E-25 T 29-03-2018 IPR000182 GNAT domain GO:0008080 GBCGDNIH2_RS06255 d4c76b060d17657b6b0de3f3a881a7e0 186 Gene3D G3DSA:3.40.630.30 12 184 3.1E-35 T 29-03-2018 GBCGDNIH2_RS09885 03419c163d852a799f20c4e56da3d6ee 466 PIRSF PIRSF018788 2 461 1.2E-236 T 29-03-2018 IPR010628 Ethanolamine ammonia lyase large subunit GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 GBCGDNIH2_RS09885 03419c163d852a799f20c4e56da3d6ee 466 Gene3D G3DSA:1.10.220.70 57 141 2.1E-41 T 29-03-2018 GBCGDNIH2_RS09885 03419c163d852a799f20c4e56da3d6ee 466 Gene3D G3DSA:3.20.20.70 144 449 7.0E-160 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS09885 03419c163d852a799f20c4e56da3d6ee 466 Gene3D G3DSA:2.30.170.30 3 54 4.0E-21 T 29-03-2018 GBCGDNIH2_RS09885 03419c163d852a799f20c4e56da3d6ee 466 Pfam PF06751 Ethanolamine ammonia lyase large subunit (EutB) 13 446 2.6E-222 T 29-03-2018 IPR010628 Ethanolamine ammonia lyase large subunit GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 GBCGDNIH2_RS07260 a459dd140124b53f5ef78eedba15c1df 171 Pfam PF07813 LTXXQ motif family protein 62 155 7.6E-10 T 29-03-2018 IPR012899 LTXXQ motif family protein GO:0042597 GBCGDNIH2_RS05815 d50f515da0d71737ec7e4c092223df9b 172 Pfam PF11014 Protein of unknown function (DUF2852) 8 147 2.1E-47 T 29-03-2018 IPR021273 Protein of unknown function DUF2852 GBCGDNIH2_RS10540 52d50011d5e8ad63e1b472fb5972a416 347 Gene3D G3DSA:3.90.226.10 84 314 4.5E-35 T 29-03-2018 GBCGDNIH2_RS10540 52d50011d5e8ad63e1b472fb5972a416 347 Pfam PF01343 Peptidase family S49 144 295 4.9E-45 T 29-03-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 GBCGDNIH2_RS10540 52d50011d5e8ad63e1b472fb5972a416 347 SUPERFAMILY SSF52096 221 281 1.19E-40 T 29-03-2018 IPR029045 ClpP/crotonase-like domain GBCGDNIH2_RS10540 52d50011d5e8ad63e1b472fb5972a416 347 SUPERFAMILY SSF52096 74 192 1.19E-40 T 29-03-2018 IPR029045 ClpP/crotonase-like domain GBCGDNIH2_RS10540 52d50011d5e8ad63e1b472fb5972a416 347 TIGRFAM TIGR00706 SppA_dom: signal peptide peptidase SppA, 36K type 90 291 8.8E-62 T 29-03-2018 IPR004635 Peptidase S49, SppA GO:0006508|GO:0008233 GBCGDNIH2_RS06500 cde5c711ccdec14300ffbf9109dbbb29 186 Pfam PF01292 Prokaryotic cytochrome b561 6 186 8.4E-25 T 29-03-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 GBCGDNIH2_RS06500 cde5c711ccdec14300ffbf9109dbbb29 186 SUPERFAMILY SSF81342 1 186 3.3E-29 T 29-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 GBCGDNIH2_RS06500 cde5c711ccdec14300ffbf9109dbbb29 186 Gene3D G3DSA:1.20.950.20 1 186 7.1E-33 T 29-03-2018 GBCGDNIH2_RS09170 33bb64f07df3b6f0aeb4cef8879e6109 277 Gene3D G3DSA:1.10.3720.10 16 269 3.4E-21 T 29-03-2018 GBCGDNIH2_RS09170 33bb64f07df3b6f0aeb4cef8879e6109 277 SUPERFAMILY SSF161098 75 256 1.02E-27 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GBCGDNIH2_RS09170 33bb64f07df3b6f0aeb4cef8879e6109 277 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 96 269 4.3E-20 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GBCGDNIH2_RS11760 08fe06e7c830955a3a942c7100570718 91 Pfam PF02583 Metal-sensitive transcriptional repressor 8 86 3.2E-16 T 29-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 GBCGDNIH2_RS04615 3a1ff5d76c776c36cf9ababd55b62ab0 250 SUPERFAMILY SSF56300 13 247 1.39E-25 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like GBCGDNIH2_RS04615 3a1ff5d76c776c36cf9ababd55b62ab0 250 Pfam PF00149 Calcineurin-like phosphoesterase 31 109 1.7E-7 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 GBCGDNIH2_RS04615 3a1ff5d76c776c36cf9ababd55b62ab0 250 Gene3D G3DSA:3.60.21.10 22 250 8.9E-24 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like GBCGDNIH2_RS02385 9760e0929880b99ea45109def8762bb6 229 Pfam PF11233 Protein of unknown function (DUF3035) 74 207 1.3E-35 T 29-03-2018 IPR021395 Protein of unknown function DUF3035 GBCGDNIH2_RS05860 6a51c8a0401d05d91f191ed1b9ec47db 275 SUPERFAMILY SSF103088 150 242 4.45E-11 T 29-03-2018 IPR006665 OmpA-like domain GBCGDNIH2_RS05860 6a51c8a0401d05d91f191ed1b9ec47db 275 Pfam PF00691 OmpA family 153 232 5.8E-8 T 29-03-2018 IPR006665 OmpA-like domain GBCGDNIH2_RS05860 6a51c8a0401d05d91f191ed1b9ec47db 275 Gene3D G3DSA:3.30.1330.60 68 245 2.5E-10 T 29-03-2018 IPR006665 OmpA-like domain GBCGDNIH2_RS09940 032d317c79c88cb6025f23bd21643f56 191 Gene3D G3DSA:2.60.500.10 63 170 3.1E-4 T 29-03-2018 GBCGDNIH2_RS08570 7665df04b746d3c06b535bc0c7bdeeb1 253 Pfam PF01925 Sulfite exporter TauE/SafE 11 245 6.6E-41 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 GBCGDNIH2_RS06925 3f5b6eaab6248a3cfb6f2f6575ba9e5c 102 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 3 102 19.552 T 29-03-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 GBCGDNIH2_RS06925 3f5b6eaab6248a3cfb6f2f6575ba9e5c 102 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 8 97 4.3E-23 T 29-03-2018 GBCGDNIH2_RS12320 454d1b101c506cb3542addd637aeb44c 253 Pfam PF09490 Probable cobalt transporter subunit (CbtA) 2 240 5.4E-73 T 29-03-2018 IPR012666 Cobalt transporter subunit CbtA, putative GBCGDNIH2_RS09200 f4d96c420ff346af27cc70e20722ad99 566 Pfam PF02366 Dolichyl-phosphate-mannose-protein mannosyltransferase 68 240 1.1E-6 T 29-03-2018 IPR003342 Glycosyl transferase family 39/83 GO:0000030|GO:0006493|GO:0016020 Reactome: R-HSA-5173105 GBCGDNIH2_RS04415 86f34c0c122975461cd7097b0b29c392 419 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 82 4.6E-19 T 29-03-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 GBCGDNIH2_RS04415 86f34c0c122975461cd7097b0b29c392 419 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 209 417 8.4E-56 T 29-03-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 GBCGDNIH2_RS12480 86b836d8bf15502d49a8713a5cbc21dd 206 SUPERFAMILY SSF53167 1 148 8.25E-20 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 GBCGDNIH2_RS12480 86b836d8bf15502d49a8713a5cbc21dd 206 Pfam PF01048 Phosphorylase superfamily 93 149 1.8E-8 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 GBCGDNIH2_RS12480 86b836d8bf15502d49a8713a5cbc21dd 206 Pfam PF01048 Phosphorylase superfamily 32 74 6.3E-6 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 GBCGDNIH2_RS12480 86b836d8bf15502d49a8713a5cbc21dd 206 Gene3D G3DSA:3.40.50.1580 13 202 2.8E-14 T 29-03-2018 GBCGDNIH2_RS12060 44a27afcd4cd286c5e9538ae0ae17434 216 Pfam PF01713 Smr domain 130 212 5.4E-12 T 29-03-2018 IPR002625 Smr domain GBCGDNIH2_RS12060 44a27afcd4cd286c5e9538ae0ae17434 216 SUPERFAMILY SSF160443 129 213 6.41E-11 T 29-03-2018 IPR002625 Smr domain GBCGDNIH2_RS05160 7ce43001eec4af6f5bbb00af0b11f9cc 331 Pfam PF05128 Domain of unknown function (DUF697) 204 328 1.9E-10 T 29-03-2018 IPR021147 Protein of unknown function DUF697 GBCGDNIH2_RS11140 1283c37a9f2c65f2b673e04db7528c68 225 SUPERFAMILY SSF53098 4 170 2.62E-54 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 GBCGDNIH2_RS11140 1283c37a9f2c65f2b673e04db7528c68 225 TIGRFAM TIGR01406 dnaQ_proteo: DNA polymerase III, epsilon subunit 3 222 6.2E-77 T 29-03-2018 IPR006309 DNA polymerase 3, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GBCGDNIH2_RS11140 1283c37a9f2c65f2b673e04db7528c68 225 Gene3D G3DSA:3.30.420.10 1 173 6.5E-43 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 GBCGDNIH2_RS11140 1283c37a9f2c65f2b673e04db7528c68 225 Pfam PF00929 Exonuclease 5 164 1.1E-33 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III GBCGDNIH2_RS11140 1283c37a9f2c65f2b673e04db7528c68 225 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 5 173 2.2E-42 T 29-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GBCGDNIH2_RS11140 1283c37a9f2c65f2b673e04db7528c68 225 SMART SM00479 3 173 1.4E-46 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III GBCGDNIH2_RS10215 bfab8e14c49c9335f1e1de072dac5aab 226 Pfam PF03588 Leucyl/phenylalanyl-tRNA protein transferase 11 182 1.9E-64 T 29-03-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 GBCGDNIH2_RS10215 bfab8e14c49c9335f1e1de072dac5aab 226 SUPERFAMILY SSF55729 7 201 2.07E-73 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase GBCGDNIH2_RS10215 bfab8e14c49c9335f1e1de072dac5aab 226 TIGRFAM TIGR00667 aat: leucyl/phenylalanyl-tRNA--protein transferase 13 198 3.8E-52 T 29-03-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 GBCGDNIH2_RS10215 bfab8e14c49c9335f1e1de072dac5aab 226 Hamap MF_00688 Leucyl/phenylalanyl-tRNA--protein transferase [aat]. 1 226 79.01 T 29-03-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 GBCGDNIH2_RS10160 51c4546df053a2ceff9b13a0a3aac3ef 384 SUPERFAMILY SSF53067 79 121 4.14E-17 T 29-03-2018 GBCGDNIH2_RS10160 51c4546df053a2ceff9b13a0a3aac3ef 384 SUPERFAMILY SSF53067 159 332 4.14E-17 T 29-03-2018 GBCGDNIH2_RS10160 51c4546df053a2ceff9b13a0a3aac3ef 384 SUPERFAMILY SSF53067 17 48 4.14E-17 T 29-03-2018 GBCGDNIH2_RS10160 51c4546df053a2ceff9b13a0a3aac3ef 384 Pfam PF03702 Anhydro-N-acetylmuramic acid kinase 16 373 3.3E-80 T 29-03-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 GBCGDNIH2_RS10160 51c4546df053a2ceff9b13a0a3aac3ef 384 Hamap MF_01270 Anhydro-N-acetylmuramic acid kinase [anmK]. 15 378 35.736 T 29-03-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 GBCGDNIH2_RS10160 51c4546df053a2ceff9b13a0a3aac3ef 384 Gene3D G3DSA:3.30.420.40 15 200 2.0E-49 T 29-03-2018 GBCGDNIH2_RS10160 51c4546df053a2ceff9b13a0a3aac3ef 384 Gene3D G3DSA:3.30.420.40 249 382 2.5E-16 T 29-03-2018 GBCGDNIH2_RS08925 369108fbd6fa667b5e4ea6ecd6e3e188 299 TIGRFAM TIGR03638 cas1_ECOLI: CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI 11 285 7.7E-86 T 29-03-2018 IPR019851 CRISPR-associated protein Cas1, ECOLI subtype GO:0004520|GO:0043571|GO:0046872 GBCGDNIH2_RS08925 369108fbd6fa667b5e4ea6ecd6e3e188 299 Pfam PF01867 CRISPR associated protein Cas1 142 245 8.4E-7 T 29-03-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 GBCGDNIH2_RS08925 369108fbd6fa667b5e4ea6ecd6e3e188 299 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 18 297 17.672 T 29-03-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 GBCGDNIH2_RS04575 8a882d7a07055324fe9ac3f516c56ea8 295 Pfam PF04228 Putative neutral zinc metallopeptidase 1 290 1.2E-118 T 29-03-2018 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative GBCGDNIH2_RS09340 83fa66a62bc7aac6460a81360bfd1bba 278 Gene3D G3DSA:1.10.260.40 1 103 2.4E-14 T 29-03-2018 GBCGDNIH2_RS09340 83fa66a62bc7aac6460a81360bfd1bba 278 Pfam PF13560 Helix-turn-helix domain 8 86 5.3E-18 T 29-03-2018 GBCGDNIH2_RS09340 83fa66a62bc7aac6460a81360bfd1bba 278 SMART SM00530 12 83 4.0E-6 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 GBCGDNIH2_RS09340 83fa66a62bc7aac6460a81360bfd1bba 278 SUPERFAMILY SSF47413 31 77 6.95E-7 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GBCGDNIH2_RS02110 63b95c0c21890544bd32e95e0935a3a0 394 Pfam PF04966 Carbohydrate-selective porin, OprB family 10 379 4.2E-80 T 29-03-2018 IPR007049 Carbohydrate-selective porin OprB GO:0005215|GO:0006810|GO:0016021 GBCGDNIH2_RS08870 a737f976da4649decb05bd0d4abbfb38 177 Pfam PF04205 FMN-binding domain 88 165 4.9E-9 T 29-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 GBCGDNIH2_RS08870 a737f976da4649decb05bd0d4abbfb38 177 SMART SM00900 87 168 7.7E-12 T 29-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 GBCGDNIH2_RS07685 d2a4df847da3cef56958e507c612854a 190 Gene3D G3DSA:3.40.50.150 1 186 1.1E-11 T 29-03-2018 GBCGDNIH2_RS00310 f9609c599bc897e0d301be56b42ab0ac 278 Gene3D G3DSA:3.90.550.10 9 221 1.3E-10 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS00310 f9609c599bc897e0d301be56b42ab0ac 278 Pfam PF13704 Glycosyl transferase family 2 13 102 1.5E-15 T 29-03-2018 GBCGDNIH2_RS00310 f9609c599bc897e0d301be56b42ab0ac 278 SUPERFAMILY SSF53448 1 134 1.41E-12 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases GBCGDNIH2_RS07775 1d95868cf93a25116411329954cf03ea 122 Pfam PF11804 Protein of unknown function (DUF3325) 8 113 3.1E-23 T 29-03-2018 IPR021762 Protein of unknown function DUF3325 GBCGDNIH2_RS10810 4fb93242e139e7bf1422ddcd276273d8 219 Gene3D G3DSA:3.90.190.10 24 185 3.3E-18 T 29-03-2018 IPR029021 Protein-tyrosine phosphatase-like GBCGDNIH2_RS10810 4fb93242e139e7bf1422ddcd276273d8 219 Pfam PF04273 Putative phosphatase (DUF442) 54 128 3.1E-6 T 29-03-2018 IPR005939 Beta-lactamase hydrolase-like GO:0016787 GBCGDNIH2_RS10810 4fb93242e139e7bf1422ddcd276273d8 219 SUPERFAMILY SSF52799 27 195 6.61E-23 T 29-03-2018 IPR029021 Protein-tyrosine phosphatase-like GBCGDNIH2_RS01715 75974b2c0b186ae5d2a610f0c715f8f2 301 SUPERFAMILY SSF52266 123 248 6.41E-11 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain GBCGDNIH2_RS01715 75974b2c0b186ae5d2a610f0c715f8f2 301 Gene3D G3DSA:3.40.50.1110 30 264 2.1E-7 T 29-03-2018 GBCGDNIH2_RS04335 74ff0a0b6e26ef3453b76d699b1fab52 220 Pfam PF06055 Exopolysaccharide synthesis, ExoD 37 199 6.2E-41 T 29-03-2018 IPR010331 Exopolysaccharide synthesis, ExoD GBCGDNIH2_RS04335 74ff0a0b6e26ef3453b76d699b1fab52 220 PIRSF PIRSF033239 12 217 2.1E-56 T 29-03-2018 IPR010331 Exopolysaccharide synthesis, ExoD GBCGDNIH2_RS07200 7a0e13d8e94ff463844bdbb0ab8db0e7 134 Pfam PF00186 Dihydrofolate reductase 3 118 1.7E-6 T 29-03-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0006545|GO:0009165|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 GBCGDNIH2_RS07200 7a0e13d8e94ff463844bdbb0ab8db0e7 134 Gene3D G3DSA:3.40.430.10 1 77 1.2E-5 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 GBCGDNIH2_RS07200 7a0e13d8e94ff463844bdbb0ab8db0e7 134 SUPERFAMILY SSF53597 2 121 1.19E-16 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 GBCGDNIH2_RS08150 dde5b582ffdcaef16e813157b08c6d25 463 Pfam PF00171 Aldehyde dehydrogenase family 3 452 5.3E-138 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 GBCGDNIH2_RS08150 dde5b582ffdcaef16e813157b08c6d25 463 SUPERFAMILY SSF53720 3 454 5.5E-139 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 GBCGDNIH2_RS08150 dde5b582ffdcaef16e813157b08c6d25 463 Gene3D G3DSA:3.40.605.10 1 248 1.8E-70 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 GBCGDNIH2_RS08150 dde5b582ffdcaef16e813157b08c6d25 463 Gene3D G3DSA:3.40.309.10 249 440 6.4E-66 T 29-03-2018 GBCGDNIH2_RS07380 fd19ae0d5ab752789d19601b060ac564 147 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 18 126 3.4E-8 T 29-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain GBCGDNIH2_RS07380 fd19ae0d5ab752789d19601b060ac564 147 SUPERFAMILY SSF53927 17 146 2.04E-22 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 GBCGDNIH2_RS07380 fd19ae0d5ab752789d19601b060ac564 147 Gene3D G3DSA:3.40.140.10 12 147 7.4E-22 T 29-03-2018 GBCGDNIH2_RS10520 30dd1f37a806fa4364c4f73934c203b0 209 Gene3D G3DSA:3.20.20.70 2 209 8.8E-61 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS10520 30dd1f37a806fa4364c4f73934c203b0 209 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 3 209 37.503 T 29-03-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 GBCGDNIH2_RS10520 30dd1f37a806fa4364c4f73934c203b0 209 SUPERFAMILY SSF51366 4 206 7.69E-52 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 GBCGDNIH2_RS10520 30dd1f37a806fa4364c4f73934c203b0 209 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 5 204 8.3E-43 T 29-03-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 GBCGDNIH2_RS04555 49de1d579e01f97ba8246b09fa8a9a1c 228 SUPERFAMILY SSF52833 68 224 1.95E-50 T 29-03-2018 IPR012336 Thioredoxin-like fold GBCGDNIH2_RS04555 49de1d579e01f97ba8246b09fa8a9a1c 228 Gene3D G3DSA:3.40.30.10 67 222 1.4E-32 T 29-03-2018 GBCGDNIH2_RS04555 49de1d579e01f97ba8246b09fa8a9a1c 228 Pfam PF02630 SCO1/SenC 65 201 2.0E-42 T 29-03-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS04550 3d065e5f9de3f413c7627e7be92c8898 339 Gene3D G3DSA:1.10.620.20 3 315 1.1E-83 T 29-03-2018 GBCGDNIH2_RS04550 3d065e5f9de3f413c7627e7be92c8898 339 PIRSF PIRSF000355 5 337 4.4E-100 T 29-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 GBCGDNIH2_RS04550 3d065e5f9de3f413c7627e7be92c8898 339 Pfam PF00268 Ribonucleotide reductase, small chain 29 301 4.3E-75 T 29-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 GBCGDNIH2_RS04550 3d065e5f9de3f413c7627e7be92c8898 339 SUPERFAMILY SSF47240 26 309 1.87E-87 T 29-03-2018 IPR009078 Ferritin-like superfamily GBCGDNIH2_RS05975 756502b8af5fcbb471f1e0cd2dce464d 324 Gene3D G3DSA:3.30.1150.10 215 324 2.1E-7 T 29-03-2018 GBCGDNIH2_RS05975 756502b8af5fcbb471f1e0cd2dce464d 324 PRINTS PR01217 Proline rich extensin signature 114 139 5.6E-9 T 29-03-2018 GBCGDNIH2_RS05975 756502b8af5fcbb471f1e0cd2dce464d 324 PRINTS PR01217 Proline rich extensin signature 89 106 5.6E-9 T 29-03-2018 GBCGDNIH2_RS05975 756502b8af5fcbb471f1e0cd2dce464d 324 PRINTS PR01217 Proline rich extensin signature 72 88 5.6E-9 T 29-03-2018 GBCGDNIH2_RS05975 756502b8af5fcbb471f1e0cd2dce464d 324 PRINTS PR01217 Proline rich extensin signature 27 39 5.6E-9 T 29-03-2018 GBCGDNIH2_RS04430 64464b1dcba60cb5af993924871e71b3 129 Pfam PF01022 Bacterial regulatory protein, arsR family 24 68 4.2E-12 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 GBCGDNIH2_RS04430 64464b1dcba60cb5af993924871e71b3 129 SUPERFAMILY SSF46785 5 94 1.21E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS04430 64464b1dcba60cb5af993924871e71b3 129 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 18 33 2.3E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 GBCGDNIH2_RS04430 64464b1dcba60cb5af993924871e71b3 129 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 50 65 2.3E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 GBCGDNIH2_RS04430 64464b1dcba60cb5af993924871e71b3 129 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 65 80 2.3E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 GBCGDNIH2_RS04430 64464b1dcba60cb5af993924871e71b3 129 SMART SM00418 19 98 1.7E-16 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 GBCGDNIH2_RS04430 64464b1dcba60cb5af993924871e71b3 129 Gene3D G3DSA:1.10.10.10 2 102 6.8E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS05195 9456dfd00e48c170677714e4f793220c 148 SUPERFAMILY SSF69118 21 143 4.08E-33 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 GBCGDNIH2_RS05195 9456dfd00e48c170677714e4f793220c 148 Pfam PF02627 Carboxymuconolactone decarboxylase family 51 135 1.9E-18 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 GBCGDNIH2_RS05195 9456dfd00e48c170677714e4f793220c 148 Gene3D G3DSA:1.20.1290.10 11 148 2.5E-32 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 GBCGDNIH2_RS10450 4e97f689204e6ff1b4d10ed594cfe875 230 Gene3D G3DSA:3.90.850.10 11 230 5.5E-74 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 GBCGDNIH2_RS10450 4e97f689204e6ff1b4d10ed594cfe875 230 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 26 229 8.5E-53 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 GBCGDNIH2_RS10450 4e97f689204e6ff1b4d10ed594cfe875 230 SUPERFAMILY SSF56529 21 230 1.15E-68 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 GBCGDNIH2_RS12530 1ebe8685afccdd61cb1305f3ffa0d63f 68 SUPERFAMILY SSF50331 1 68 4.89E-21 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal GBCGDNIH2_RS12530 1ebe8685afccdd61cb1305f3ffa0d63f 68 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 1 67 1.6E-22 T 29-03-2018 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 GBCGDNIH2_RS12530 1ebe8685afccdd61cb1305f3ffa0d63f 68 Pfam PF03459 TOBE domain 4 66 2.8E-19 T 29-03-2018 IPR005116 Transport-associated OB, type 1 GBCGDNIH2_RS12530 1ebe8685afccdd61cb1305f3ffa0d63f 68 Gene3D G3DSA:2.40.50.100 1 68 1.5E-21 T 29-03-2018 GBCGDNIH2_RS00170 eabf45f4af32b28a1ad131374f736ef4 232 SUPERFAMILY SSF89392 66 229 2.71E-14 T 29-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX GBCGDNIH2_RS00170 eabf45f4af32b28a1ad131374f736ef4 232 Pfam PF03548 Outer membrane lipoprotein carrier protein LolA 77 229 1.8E-6 T 29-03-2018 IPR004564 Outer membrane lipoprotein carrier protein LolA-like GBCGDNIH2_RS00170 eabf45f4af32b28a1ad131374f736ef4 232 Gene3D G3DSA:2.50.20.10 65 230 5.6E-17 T 29-03-2018 GBCGDNIH2_RS10575 f2dc4d6f7bed0e5845a54aa442351e41 261 Pfam PF05275 Copper resistance protein B precursor (CopB) 56 261 4.1E-80 T 29-03-2018 IPR007939 Copper resistance B precursor GO:0005507|GO:0006878|GO:0009279 GBCGDNIH2_RS10575 f2dc4d6f7bed0e5845a54aa442351e41 261 Gene3D G3DSA:2.40.128.130 115 259 8.4E-5 T 29-03-2018 GBCGDNIH2_RS08200 0911c59aaa7225da43179ccdf52785a0 181 Pfam PF09374 Predicted Peptidoglycan domain 113 170 1.7E-8 T 29-03-2018 IPR018537 Peptidoglycan binding domain GBCGDNIH2_RS08200 0911c59aaa7225da43179ccdf52785a0 181 SUPERFAMILY SSF53955 3 174 1.77E-37 T 29-03-2018 IPR023346 Lysozyme-like domain GBCGDNIH2_RS08200 0911c59aaa7225da43179ccdf52785a0 181 Pfam PF05838 Glycosyl hydrolase 108 15 105 8.3E-19 T 29-03-2018 IPR008565 Protein of unknown function DUF847 GBCGDNIH2_RS08200 0911c59aaa7225da43179ccdf52785a0 181 Gene3D G3DSA:1.20.141.10 1 180 2.8E-37 T 29-03-2018 GBCGDNIH2_RS01185 feb2a78c15833807ebeedf57a166060b 255 Pfam PF04116 Fatty acid hydroxylase superfamily 61 203 2.4E-19 T 29-03-2018 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0008610|GO:0016491|GO:0055114 GBCGDNIH2_RS04605 e0f707e24923abc192aadfe6f2766246 543 SMART SM00880 256 530 2.9E-62 T 29-03-2018 IPR007899 CHAD domain GBCGDNIH2_RS04605 e0f707e24923abc192aadfe6f2766246 543 Pfam PF05235 CHAD domain 274 494 3.2E-45 T 29-03-2018 IPR007899 CHAD domain GBCGDNIH2_RS06840 cbaff6426ccd17a31d179e22dc21e600 207 TIGRFAM TIGR02842 CyoC: cytochrome o ubiquinol oxidase, subunit III 26 207 8.4E-81 T 29-03-2018 IPR014206 Cytochrome o ubiquinol oxidase, subunit III GO:0005886|GO:0008827|GO:0019646 GBCGDNIH2_RS06840 cbaff6426ccd17a31d179e22dc21e600 207 Gene3D G3DSA:1.20.120.80 20 207 7.3E-49 T 29-03-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS06840 cbaff6426ccd17a31d179e22dc21e600 207 Pfam PF00510 Cytochrome c oxidase subunit III 27 205 2.0E-13 T 29-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS06840 cbaff6426ccd17a31d179e22dc21e600 207 SUPERFAMILY SSF81452 15 205 1.44E-54 T 29-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS06035 2709cf8b841a6b7900b7eca6234380b4 531 SUPERFAMILY SSF56235 3 531 2.24E-163 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal GBCGDNIH2_RS06035 2709cf8b841a6b7900b7eca6234380b4 531 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 254 273 7.0E-39 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 GBCGDNIH2_RS06035 2709cf8b841a6b7900b7eca6234380b4 531 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 109 127 7.0E-39 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 GBCGDNIH2_RS06035 2709cf8b841a6b7900b7eca6234380b4 531 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 377 395 7.0E-39 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 GBCGDNIH2_RS06035 2709cf8b841a6b7900b7eca6234380b4 531 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 408 423 7.0E-39 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 GBCGDNIH2_RS06035 2709cf8b841a6b7900b7eca6234380b4 531 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 353 371 7.0E-39 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 GBCGDNIH2_RS06035 2709cf8b841a6b7900b7eca6234380b4 531 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 39 64 7.0E-39 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 GBCGDNIH2_RS06035 2709cf8b841a6b7900b7eca6234380b4 531 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 127 146 7.0E-39 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 GBCGDNIH2_RS06035 2709cf8b841a6b7900b7eca6234380b4 531 Pfam PF01019 Gamma-glutamyltranspeptidase 32 526 1.8E-142 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 GBCGDNIH2_RS07605 f2efb265225936d0dd2f84f51de86267 263 Gene3D G3DSA:3.30.565.40 44 140 2.8E-7 T 29-03-2018 GBCGDNIH2_RS03340 58a97316281f616eae50405e0411f9fd 190 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 20 180 1.2E-56 T 29-03-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 GBCGDNIH2_RS03340 58a97316281f616eae50405e0411f9fd 190 SUPERFAMILY SSF52540 20 182 1.27E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS03340 58a97316281f616eae50405e0411f9fd 190 Gene3D G3DSA:3.40.50.300 19 182 4.9E-56 T 29-03-2018 GBCGDNIH2_RS03340 58a97316281f616eae50405e0411f9fd 190 PIRSF PIRSF006135 18 184 2.7E-48 T 29-03-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 GBCGDNIH2_RS03260 27a624af5564a8fc47dd4810201ed769 326 Gene3D G3DSA:3.40.50.10800 25 107 1.6E-17 T 29-03-2018 GBCGDNIH2_RS03260 27a624af5564a8fc47dd4810201ed769 326 Hamap MF_00568 Quinolinate synthase A [nadA]. 27 326 43.226 T 29-03-2018 IPR023066 Quinolinate synthase A, type 2 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 GBCGDNIH2_RS03260 27a624af5564a8fc47dd4810201ed769 326 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 31 326 1.5E-93 T 29-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 GBCGDNIH2_RS03260 27a624af5564a8fc47dd4810201ed769 326 Gene3D G3DSA:3.40.50.10800 203 308 2.6E-32 T 29-03-2018 GBCGDNIH2_RS03260 27a624af5564a8fc47dd4810201ed769 326 Gene3D G3DSA:3.40.50.10800 112 202 3.3E-22 T 29-03-2018 GBCGDNIH2_RS03260 27a624af5564a8fc47dd4810201ed769 326 Pfam PF02445 Quinolinate synthetase A protein 32 325 5.4E-112 T 29-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 GBCGDNIH2_RS03260 27a624af5564a8fc47dd4810201ed769 326 SUPERFAMILY SSF142754 30 325 7.45E-108 T 29-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 GBCGDNIH2_RS07290 89eeb9246ff4a77a48dbeec4c7b267ef 189 Gene3D G3DSA:1.10.10.10 86 135 0.18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS07290 89eeb9246ff4a77a48dbeec4c7b267ef 189 Pfam PF06242 Protein of unknown function (DUF1013) 29 165 8.4E-66 T 29-03-2018 IPR010421 Protein of unknown function DUF1013 GBCGDNIH2_RS10950 a83fcc9248a9473a1c89ec3ad62f1e0c 243 Gene3D G3DSA:1.20.5.340 25 94 1.7E-5 T 29-03-2018 GBCGDNIH2_RS10950 a83fcc9248a9473a1c89ec3ad62f1e0c 243 Pfam PF09849 Uncharacterized protein conserved in bacteria (DUF2076) 1 226 1.6E-51 T 29-03-2018 IPR018648 Protein of unknown function DUF2076 GBCGDNIH2_RS01400 9de6cf94e6943b5af90c0731346bb376 59 Pfam PF07896 Protein of unknown function (DUF1674) 31 59 1.4E-14 T 29-03-2018 IPR012875 Protein of unknown function DUF1674 GBCGDNIH2_RS11275 59f53de6502facf97784f2e5610fb392 528 Pfam PF13520 Amino acid permease 10 445 1.4E-44 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 GBCGDNIH2_RS11275 59f53de6502facf97784f2e5610fb392 528 PIRSF PIRSF006060 1 527 1.2E-68 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 GBCGDNIH2_RS04460 3946044ff582911ca3a56acaa84155fa 266 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 71 233 2.2E-22 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain GBCGDNIH2_RS04460 3946044ff582911ca3a56acaa84155fa 266 Gene3D G3DSA:3.40.50.1110 47 260 7.6E-28 T 29-03-2018 GBCGDNIH2_RS04460 3946044ff582911ca3a56acaa84155fa 266 SUPERFAMILY SSF52266 38 259 2.83E-39 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain GBCGDNIH2_RS03735 0b5321f2eb232dcc3bfe79439f1a31e3 174 Pfam PF02417 Chromate transporter 8 170 1.6E-34 T 29-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 GBCGDNIH2_RS02705 eb95c459b3a697052cbe393fcf531c66 148 Pfam PF03928 Haem-degrading 10 139 3.5E-22 T 29-03-2018 IPR005624 Haem-degrading GBCGDNIH2_RS02705 eb95c459b3a697052cbe393fcf531c66 148 SUPERFAMILY SSF143744 6 142 5.62E-29 T 29-03-2018 GBCGDNIH2_RS01250 ec291ed378dc9c4af13447e31cb525a5 479 Pfam PF13440 Polysaccharide biosynthesis protein 36 313 2.8E-45 T 29-03-2018 GBCGDNIH2_RS10435 13236ca0573e753f0490efca830cfaa1 172 Pfam PF03734 L,D-transpeptidase catalytic domain 16 160 3.4E-7 T 29-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 GBCGDNIH2_RS10435 13236ca0573e753f0490efca830cfaa1 172 Gene3D G3DSA:2.40.440.10 2 166 4.6E-4 T 29-03-2018 GBCGDNIH2_RS02490 98e3665de88a8cf4359fa819cccb902c 292 SUPERFAMILY SSF54001 100 269 2.06E-37 T 29-03-2018 GBCGDNIH2_RS02490 98e3665de88a8cf4359fa819cccb902c 292 Gene3D G3DSA:3.90.260.10 164 289 1.7E-6 T 29-03-2018 IPR002931 Transglutaminase-like GBCGDNIH2_RS02490 98e3665de88a8cf4359fa819cccb902c 292 SMART SM00460 175 244 2.5E-17 T 29-03-2018 IPR002931 Transglutaminase-like GBCGDNIH2_RS02490 98e3665de88a8cf4359fa819cccb902c 292 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 6 82 6.3E-19 T 29-03-2018 IPR013589 Bacterial transglutaminase-like, N-terminal GBCGDNIH2_RS02490 98e3665de88a8cf4359fa819cccb902c 292 Pfam PF01841 Transglutaminase-like superfamily 152 242 2.8E-19 T 29-03-2018 IPR002931 Transglutaminase-like GBCGDNIH2_RS08650 22b945d3658065612b3506f92b3ec269 215 SUPERFAMILY SSF48403 97 156 1.23E-6 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain GBCGDNIH2_RS08650 22b945d3658065612b3506f92b3ec269 215 Gene3D G3DSA:1.25.40.20 96 173 4.1E-8 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain GBCGDNIH2_RS05845 ffa3cda7d0e4adfb8eae91c077f91fe3 227 Pfam PF06912 Protein of unknown function (DUF1275) 22 212 1.1E-28 T 29-03-2018 IPR010699 Protein of unknown function DUF1275 GBCGDNIH2_RS12040 65eb11742d7f392bb21417adf1e8ba53 261 Pfam PF02754 Cysteine-rich domain 15 96 1.7E-12 T 29-03-2018 IPR004017 Cysteine-rich domain GBCGDNIH2_RS12040 65eb11742d7f392bb21417adf1e8ba53 261 Pfam PF02754 Cysteine-rich domain 144 227 5.1E-14 T 29-03-2018 IPR004017 Cysteine-rich domain GBCGDNIH2_RS12315 33c66adbd29bbbfa68c25e58bd538313 73 Pfam PF09489 Probable cobalt transporter subunit (CbtB) 36 73 4.5E-12 T 29-03-2018 IPR012667 Cobalt transporter subunit CbtB, putative GBCGDNIH2_RS01345 7f52db86f758b35e6f875c498b60de58 225 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 8 215 3.2E-39 T 29-03-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 GBCGDNIH2_RS01345 7f52db86f758b35e6f875c498b60de58 225 Pfam PF01914 MarC family integral membrane protein 9 217 7.5E-41 T 29-03-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 GBCGDNIH2_RS04960 212d88142d941fea8899192e4d76b06e 290 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 25 287 5.5E-80 T 29-03-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 GBCGDNIH2_RS04960 212d88142d941fea8899192e4d76b06e 290 SUPERFAMILY SSF161098 39 281 1.57E-29 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GBCGDNIH2_RS04960 212d88142d941fea8899192e4d76b06e 290 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 285 1.1E-21 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GBCGDNIH2_RS04960 212d88142d941fea8899192e4d76b06e 290 Gene3D G3DSA:1.10.3720.10 12 284 6.8E-34 T 29-03-2018 GBCGDNIH2_RS10665 cb58708ffb2abe8c00a02a11fd8b4915 258 Pfam PF01863 Protein of unknown function DUF45 50 247 3.7E-46 T 29-03-2018 IPR002725 Protein of unknown function DUF45 GBCGDNIH2_RS09580 3861e1cef0e245e12b2f35210924186c 111 SMART SM00834 1 41 1.2E-14 T 29-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain GBCGDNIH2_RS09580 3861e1cef0e245e12b2f35210924186c 111 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 49 4.9E-17 T 29-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain GBCGDNIH2_RS09580 3861e1cef0e245e12b2f35210924186c 111 Pfam PF09723 Zinc ribbon domain 1 39 1.9E-12 T 29-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain GBCGDNIH2_RS02605 84f2f922420561664083a2eff278ecba 507 Pfam PF04293 SpoVR like protein 13 448 7.5E-167 T 29-03-2018 IPR007390 Sporulation stage V, protein R GBCGDNIH2_RS07280 29b5c8b4bce00c18e2389a1fb1d3795f 281 Pfam PF02308 MgtC family 62 183 8.6E-34 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 GBCGDNIH2_RS07280 29b5c8b4bce00c18e2389a1fb1d3795f 281 PRINTS PR01837 MgtC/SapB protein signature 110 132 1.1E-37 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 GBCGDNIH2_RS07280 29b5c8b4bce00c18e2389a1fb1d3795f 281 PRINTS PR01837 MgtC/SapB protein signature 65 84 1.1E-37 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 GBCGDNIH2_RS07280 29b5c8b4bce00c18e2389a1fb1d3795f 281 PRINTS PR01837 MgtC/SapB protein signature 137 161 1.1E-37 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 GBCGDNIH2_RS07280 29b5c8b4bce00c18e2389a1fb1d3795f 281 PRINTS PR01837 MgtC/SapB protein signature 84 102 1.1E-37 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 GBCGDNIH2_RS04730 a16b368eadcef857cf33b19d2c7594c1 422 TIGRFAM TIGR04474 tcm_partner: three-Cys-motif partner protein 16 290 5.6E-65 T 29-03-2018 IPR031009 Three-Cys-motif partner protein GBCGDNIH2_RS07635 48a1c5c03d93468d9b01a585bba9ca96 404 Gene3D G3DSA:3.30.1330.60 96 395 6.2E-5 T 29-03-2018 IPR006665 OmpA-like domain GBCGDNIH2_RS07635 48a1c5c03d93468d9b01a585bba9ca96 404 SUPERFAMILY SSF103088 291 389 1.7E-5 T 29-03-2018 IPR006665 OmpA-like domain GBCGDNIH2_RS06685 b4b928f1866c8268d98cce45276cfb0c 181 SUPERFAMILY SSF158694 14 171 2.62E-47 T 29-03-2018 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 GBCGDNIH2_RS06685 b4b928f1866c8268d98cce45276cfb0c 181 Gene3D G3DSA:1.10.3330.10 12 178 1.2E-49 T 29-03-2018 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 GBCGDNIH2_RS06685 b4b928f1866c8268d98cce45276cfb0c 181 TIGRFAM TIGR03164 UHCUDC: OHCU decarboxylase 15 168 2.0E-54 T 29-03-2018 IPR017580 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase, type 1 GO:0019428 KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 GBCGDNIH2_RS06685 b4b928f1866c8268d98cce45276cfb0c 181 Pfam PF09349 OHCU decarboxylase 14 167 5.1E-43 T 29-03-2018 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 GBCGDNIH2_RS00885 1e5d2229f21d17046019eae76c58071f 92 Pfam PF04267 Sarcosine oxidase, delta subunit family 2 80 3.4E-31 T 29-03-2018 IPR006279 Sarcosine oxidase, delta subunit, heterotetrameric GO:0008115|GO:0046653 KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 GBCGDNIH2_RS00885 1e5d2229f21d17046019eae76c58071f 92 Gene3D G3DSA:3.30.2270.10 1 85 3.8E-32 T 29-03-2018 GBCGDNIH2_RS07795 4aa4f1b876c9baef68db82907c3b0d75 498 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 52 222 1.4E-25 T 29-03-2018 GBCGDNIH2_RS07810 71f8cc48c74a66b375c219dc4ef4c427 389 Pfam PF01098 Cell cycle protein 41 371 2.7E-88 T 29-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 GBCGDNIH2_RS07810 71f8cc48c74a66b375c219dc4ef4c427 389 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 24 371 1.7E-114 T 29-03-2018 IPR011923 Rod shape-determining protein RodA GO:0008360|GO:0016021 GBCGDNIH2_RS05570 6049169e04a21a630483467b3ac61f77 381 Pfam PF10150 Ribonuclease E/G family 176 297 9.0E-22 T 29-03-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 GBCGDNIH2_RS05570 6049169e04a21a630483467b3ac61f77 381 SUPERFAMILY SSF50249 47 109 7.54E-6 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold GBCGDNIH2_RS05570 6049169e04a21a630483467b3ac61f77 381 Gene3D G3DSA:2.40.50.140 44 110 1.7E-5 T 29-03-2018 GBCGDNIH2_RS03635 19e27e3b7b03c0c5cde93610f86e895a 197 Gene3D G3DSA:3.40.1800.10 82 156 1.1E-18 T 29-03-2018 GBCGDNIH2_RS03635 19e27e3b7b03c0c5cde93610f86e895a 197 Pfam PF14279 HNH endonuclease 103 154 1.5E-16 T 29-03-2018 IPR029471 HNH endonuclease 5 GBCGDNIH2_RS03635 19e27e3b7b03c0c5cde93610f86e895a 197 SMART SM00507 90 143 5.2E-9 T 29-03-2018 IPR003615 HNH nuclease GBCGDNIH2_RS06475 9233e161470722c00d942dd3594c356e 243 Pfam PF12679 ABC-2 family transporter protein 65 235 8.5E-11 T 29-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 GBCGDNIH2_RS01020 1edb2c18414e2f79459d3082c5ff7a29 178 Pfam PF13302 Acetyltransferase (GNAT) domain 15 153 2.5E-20 T 29-03-2018 IPR000182 GNAT domain GO:0008080 GBCGDNIH2_RS01020 1edb2c18414e2f79459d3082c5ff7a29 178 SUPERFAMILY SSF55729 10 156 2.52E-26 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase GBCGDNIH2_RS01020 1edb2c18414e2f79459d3082c5ff7a29 178 Gene3D G3DSA:3.40.630.30 5 174 3.0E-19 T 29-03-2018 GBCGDNIH2_RS01560 e34fbe2dc74be3e8ef543b92ae8b38ec 381 Pfam PF01594 AI-2E family transporter 40 355 2.0E-48 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like GBCGDNIH2_RS05740 813268dfb7c793010fc695306564d350 90 TIGRFAM TIGR04360 other_trbK: conjugative transfer region protein TrbK 14 77 4.4E-16 T 29-03-2018 IPR027587 Conjugative transfer region protein TrbK GBCGDNIH2_RS01190 39af3b10e280c28554b95edc9b865750 384 SUPERFAMILY SSF55729 13 118 2.95E-21 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase GBCGDNIH2_RS01190 39af3b10e280c28554b95edc9b865750 384 SUPERFAMILY SSF55729 146 378 2.95E-21 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase GBCGDNIH2_RS01190 39af3b10e280c28554b95edc9b865750 384 Gene3D G3DSA:3.40.630.30 195 383 7.6E-13 T 29-03-2018 GBCGDNIH2_RS01190 39af3b10e280c28554b95edc9b865750 384 Gene3D G3DSA:3.40.630.30 9 181 3.0E-5 T 29-03-2018 GBCGDNIH2_RS09335 7d91c56255446386eff2aaa880a75e76 300 Pfam PF13460 NAD(P)H-binding 7 164 1.7E-15 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS09335 7d91c56255446386eff2aaa880a75e76 300 Gene3D G3DSA:3.40.50.720 1 292 9.9E-35 T 29-03-2018 GBCGDNIH2_RS09335 7d91c56255446386eff2aaa880a75e76 300 SUPERFAMILY SSF51735 1 283 5.03E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS01285 222086067d121ae3be2d71b2cfa5be18 129 Pfam PF06155 Protein of unknown function (DUF971) 21 105 1.7E-28 T 29-03-2018 IPR010376 Domain of unknown function DUF971 Reactome: R-HSA-71262 GBCGDNIH2_RS10610 0734527e73a9b4ee3db4a5bbbb148f08 438 Pfam PF01594 AI-2E family transporter 94 420 4.8E-56 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like GBCGDNIH2_RS10315 de3eb443a86435ef2ce820e0a146dd75 423 PIRSF PIRSF028704 7 408 7.1E-74 T 29-03-2018 IPR014550 Uncharacterised conserved protein UCP028704, OpgC GBCGDNIH2_RS10315 de3eb443a86435ef2ce820e0a146dd75 423 Pfam PF10129 OpgC protein 27 387 1.7E-100 T 29-03-2018 IPR014550 Uncharacterised conserved protein UCP028704, OpgC GBCGDNIH2_RS02875 2c1014911e6619d1c6e7d84dbee85155 69 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 2 61 17.658 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02875 2c1014911e6619d1c6e7d84dbee85155 69 Gene3D G3DSA:1.10.287.310 2 66 4.3E-23 T 29-03-2018 GBCGDNIH2_RS02875 2c1014911e6619d1c6e7d84dbee85155 69 TIGRFAM TIGR00012 L29: ribosomal protein uL29 6 61 3.8E-23 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02875 2c1014911e6619d1c6e7d84dbee85155 69 SUPERFAMILY SSF46561 3 64 6.8E-21 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS02875 2c1014911e6619d1c6e7d84dbee85155 69 Pfam PF00831 Ribosomal L29 protein 6 61 5.4E-24 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GBCGDNIH2_RS09025 70adaf19981effdc2f588d69e1bedef1 178 Gene3D G3DSA:1.20.58.130 47 162 1.2E-5 T 29-03-2018 GBCGDNIH2_RS02215 cd1a013949f96bac0f3d1d280a30948a 373 Pfam PF01098 Cell cycle protein 22 367 2.0E-73 T 29-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 GBCGDNIH2_RS02215 cd1a013949f96bac0f3d1d280a30948a 373 Gene3D G3DSA:3.40.50.720 25 352 2.6E-4 T 29-03-2018 GBCGDNIH2_RS00615 9e3b5af23781c37d9f38ace46f28b539 1362 Pfam PF04357 TamB, inner membrane protein subunit of TAM complex 1012 1362 9.6E-60 T 29-03-2018 IPR007452 Translocation and assembly module TamB GBCGDNIH2_RS08355 2a8ec97bbc1407663a498f0c096d0142 131 Pfam PF13262 Protein of unknown function (DUF4054) 16 118 2.2E-17 T 29-03-2018 IPR025127 Protein of unknown function DUF4054 GBCGDNIH2_RS00955 fd5a1183e68329f5768a1861761a168f 480 Gene3D G3DSA:3.90.820.10 31 71 0.3 T 29-03-2018 GBCGDNIH2_RS00955 fd5a1183e68329f5768a1861761a168f 480 Gene3D G3DSA:3.90.820.10 251 291 0.5 T 29-03-2018 GBCGDNIH2_RS00955 fd5a1183e68329f5768a1861761a168f 480 Pfam PF04403 Paraquat-inducible protein A 287 441 2.4E-53 T 29-03-2018 IPR007498 Paraquat-inducible protein A GBCGDNIH2_RS00955 fd5a1183e68329f5768a1861761a168f 480 Pfam PF04403 Paraquat-inducible protein A 72 223 6.0E-39 T 29-03-2018 IPR007498 Paraquat-inducible protein A GBCGDNIH2_RS08145 f58583994c475f7906d452dbf7904eb2 197 SUPERFAMILY SSF53697 3 192 3.78E-50 T 29-03-2018 GBCGDNIH2_RS08145 f58583994c475f7906d452dbf7904eb2 197 Gene3D G3DSA:3.40.50.10490 4 194 2.8E-41 T 29-03-2018 GBCGDNIH2_RS08145 f58583994c475f7906d452dbf7904eb2 197 Hamap MF_00067 Phosphoheptose isomerase [gmhA]. 2 191 35.037 T 29-03-2018 IPR004515 Phosphoheptose isomerase GO:0005737|GO:0008968 KEGG: 00540+5.3.1.28|MetaCyc: PWY-6478 GBCGDNIH2_RS08145 f58583994c475f7906d452dbf7904eb2 197 Pfam PF13580 SIS domain 25 148 6.1E-27 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 GBCGDNIH2_RS10285 f0f928d8d69b6ad6ec72ebbe8b82adea 195 Pfam PF14371 Domain of unknown function (DUF4412) 76 157 1.0E-4 T 29-03-2018 IPR025524 Domain of unknown function DUF4412 GBCGDNIH2_RS03740 9579abc30d53c7d21e5f429875efbc89 259 Pfam PF14023 Protein of unknown function (DUF4239) 69 244 4.0E-6 T 29-03-2018 IPR025333 Protein of unknown function DUF4239 GBCGDNIH2_RS01825 d4f8c9680d5a1eafbceb7eaa02d2b69f 191 Gene3D G3DSA:1.25.40.10 13 123 2.4E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS01825 d4f8c9680d5a1eafbceb7eaa02d2b69f 191 Gene3D G3DSA:1.25.40.10 129 169 0.06 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS01825 d4f8c9680d5a1eafbceb7eaa02d2b69f 191 SUPERFAMILY SSF48452 35 167 1.22E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GBCGDNIH2_RS02015 9e66c46629060a5b8c7d38d1d9b79831 137 Pfam PF05443 ROS/MUCR transcriptional regulator protein 9 130 3.6E-50 T 29-03-2018 IPR008807 ROSMUCR transcriptional regulator GO:0003677|GO:0006355|GO:0008270 GBCGDNIH2_RS08290 2213e78ac854a2315629bef53e0ad7e5 124 Gene3D G3DSA:3.10.450.40 3 119 3.3E-9 T 29-03-2018 GBCGDNIH2_RS01905 97890630646b492d5bab81dd47ab53e2 451 SUPERFAMILY SSF56112 86 149 2.31E-26 T 29-03-2018 IPR011009 Protein kinase-like domain GBCGDNIH2_RS01905 97890630646b492d5bab81dd47ab53e2 451 SUPERFAMILY SSF56112 181 304 2.31E-26 T 29-03-2018 IPR011009 Protein kinase-like domain GBCGDNIH2_RS01905 97890630646b492d5bab81dd47ab53e2 451 Pfam PF03109 ABC1 family 104 218 2.7E-29 T 29-03-2018 IPR004147 UbiB domain GBCGDNIH2_RS01905 97890630646b492d5bab81dd47ab53e2 451 Gene3D G3DSA:3.30.200.20 95 232 4.1E-23 T 29-03-2018 GBCGDNIH2_RS01905 97890630646b492d5bab81dd47ab53e2 451 Gene3D G3DSA:1.10.510.10 236 331 3.6E-5 T 29-03-2018 GBCGDNIH2_RS12055 d281b42f96326c4e84d6734fb7705f76 237 Gene3D G3DSA:3.40.50.10420 55 228 4.8E-29 T 29-03-2018 GBCGDNIH2_RS12055 d281b42f96326c4e84d6734fb7705f76 237 SUPERFAMILY SSF100950 57 226 3.77E-33 T 29-03-2018 GBCGDNIH2_RS12055 d281b42f96326c4e84d6734fb7705f76 237 Pfam PF02589 LUD domain 135 226 7.6E-20 T 29-03-2018 IPR003741 LUD domain GBCGDNIH2_RS07770 55bcfe4b8a4a05b072ca46a6ee6c3a4e 546 Pfam PF03929 PepSY-associated TM region 11 385 1.6E-58 T 29-03-2018 IPR005625 PepSY-associated TM protein GBCGDNIH2_RS00915 1790eac540dfc67bbdbe24c49e5f6648 568 Pfam PF03814 Potassium-transporting ATPase A subunit 11 560 8.0E-246 T 29-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 GBCGDNIH2_RS00915 1790eac540dfc67bbdbe24c49e5f6648 568 PIRSF PIRSF001294 1 564 9.6E-241 T 29-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 GBCGDNIH2_RS00915 1790eac540dfc67bbdbe24c49e5f6648 568 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 2 562 35.7 T 29-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 GBCGDNIH2_RS00915 1790eac540dfc67bbdbe24c49e5f6648 568 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 1 562 1.6E-233 T 29-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 GBCGDNIH2_RS10245 6725b1d23cd1597db8292d9558a4f86e 84 Pfam PF11730 Protein of unknown function (DUF3297) 6 76 1.5E-39 T 29-03-2018 IPR021724 Protein of unknown function DUF3297 GBCGDNIH2_RS10905 9bc8e742ef985a8fd3c85e38c1a72821 62 Pfam PF04588 Hypoxia induced protein conserved region 7 56 2.3E-11 T 29-03-2018 IPR007667 Hypoxia induced protein, domain GBCGDNIH2_RS12555 d1d69c2ea4d22962475179734a106148 254 Pfam PF02602 Uroporphyrinogen-III synthase HemD 25 250 1.7E-33 T 29-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 GBCGDNIH2_RS12555 d1d69c2ea4d22962475179734a106148 254 Gene3D G3DSA:3.40.50.10090 123 254 7.5E-16 T 29-03-2018 GBCGDNIH2_RS12555 d1d69c2ea4d22962475179734a106148 254 Gene3D G3DSA:3.40.50.10090 11 122 1.4E-13 T 29-03-2018 GBCGDNIH2_RS12555 d1d69c2ea4d22962475179734a106148 254 SUPERFAMILY SSF69618 13 253 6.41E-40 T 29-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 GBCGDNIH2_RS07580 d7d7b8354eb525d1c514eb9fe67edc3f 273 Pfam PF02405 Permease MlaE 62 271 5.1E-34 T 29-03-2018 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 GBCGDNIH2_RS07490 56cf47c68639046a072f0d17b89e1dfb 314 Pfam PF04116 Fatty acid hydroxylase superfamily 131 267 3.0E-31 T 29-03-2018 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0008610|GO:0016491|GO:0055114 GBCGDNIH2_RS01455 0e0cd85b8ec94990a623e8e5be32b5de 332 SUPERFAMILY SSF46626 174 282 2.79E-16 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 GBCGDNIH2_RS01455 0e0cd85b8ec94990a623e8e5be32b5de 332 Gene3D G3DSA:1.10.760.10 59 162 3.9E-23 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 GBCGDNIH2_RS01455 0e0cd85b8ec94990a623e8e5be32b5de 332 SUPERFAMILY SSF46626 82 167 1.1E-23 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 GBCGDNIH2_RS01455 0e0cd85b8ec94990a623e8e5be32b5de 332 Gene3D G3DSA:1.10.760.10 177 276 1.3E-14 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 GBCGDNIH2_RS01455 0e0cd85b8ec94990a623e8e5be32b5de 332 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 185 273 2.2E-9 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 GBCGDNIH2_RS04340 b9faad3080dc459b37b91b0e9474f1cb 403 SUPERFAMILY SSF55681 11 306 2.24E-45 T 29-03-2018 GBCGDNIH2_RS04340 b9faad3080dc459b37b91b0e9474f1cb 403 Gene3D G3DSA:3.30.930.10 4 338 1.0E-36 T 29-03-2018 GBCGDNIH2_RS04340 b9faad3080dc459b37b91b0e9474f1cb 403 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 21 374 22.051 T 29-03-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 GBCGDNIH2_RS04340 b9faad3080dc459b37b91b0e9474f1cb 403 Pfam PF13393 Histidyl-tRNA synthetase 14 327 6.9E-90 T 29-03-2018 GBCGDNIH2_RS04775 f694e699574aa991f38311440ce90fb6 144 Pfam PF05119 Phage terminase, small subunit 29 125 2.9E-12 T 29-03-2018 IPR006448 Putative phage terminase, small subunit, P27 family GBCGDNIH2_RS03615 c99fa6ffbaf238c900154c3511ef1988 293 Gene3D G3DSA:3.40.50.720 3 286 7.9E-18 T 29-03-2018 GBCGDNIH2_RS03615 c99fa6ffbaf238c900154c3511ef1988 293 SUPERFAMILY SSF51735 5 282 2.48E-25 T 29-03-2018 IPR016040 NAD(P)-binding domain GBCGDNIH2_RS10055 35db84b26b4a6086928ff650e54462a9 101 Pfam PF05402 Coenzyme PQQ synthesis protein D (PqqD) 36 99 2.3E-14 T 29-03-2018 IPR008792 Coenzyme PQQ synthesis D GBCGDNIH2_RS10055 35db84b26b4a6086928ff650e54462a9 101 TIGRFAM TIGR03859 PQQ_PqqD: coenzyme PQQ biosynthesis protein PqqD 19 99 1.0E-21 T 29-03-2018 IPR022479 Coenzyme PQQ synthesis D, bacteria GO:0018189|GO:0048038 GBCGDNIH2_RS03825 a872ae1b29d43b6066abeec32e2fd511 369 Pfam PF01757 Acyltransferase family 22 346 8.9E-17 T 29-03-2018 IPR002656 Acyltransferase 3 GO:0016747 GBCGDNIH2_RS06235 6ce00222c593b2c44dd7e77f27dfcb61 153 SUPERFAMILY SSF51182 36 116 2.23E-14 T 29-03-2018 IPR011051 RmlC-like cupin domain GBCGDNIH2_RS06235 6ce00222c593b2c44dd7e77f27dfcb61 153 Pfam PF07883 Cupin domain 44 108 1.3E-7 T 29-03-2018 IPR013096 Cupin 2, conserved barrel GBCGDNIH2_RS06235 6ce00222c593b2c44dd7e77f27dfcb61 153 Gene3D G3DSA:2.60.120.10 13 134 4.5E-16 T 29-03-2018 IPR014710 RmlC-like jelly roll fold GBCGDNIH2_RS04910 28086c41a85e66a64b950089554a7d19 97 Pfam PF09907 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system 19 92 7.0E-32 T 29-03-2018 IPR018669 Toxin-antitoxin system, toxin component, HigB, putative GO:0016788 GBCGDNIH2_RS08910 c7e6f2dddaa3c7de23233ee9a44b339b 386 Pfam PF09344 CT1975-like protein 7 373 1.9E-97 T 29-03-2018 IPR010148 CRISPR-associated protein, CT1975 GBCGDNIH2_RS08910 c7e6f2dddaa3c7de23233ee9a44b339b 386 TIGRFAM TIGR01869 casC_Cse4: CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI 5 330 5.8E-90 T 29-03-2018 IPR010148 CRISPR-associated protein, CT1975 GBCGDNIH2_RS09645 21a8fb517a674cf174e810a890e2a229 216 SUPERFAMILY SSF141259 27 92 3.4E-13 T 29-03-2018 IPR003711 CarD-like/TRCF domain GBCGDNIH2_RS09645 21a8fb517a674cf174e810a890e2a229 216 Pfam PF02559 CarD-like/TRCF domain 29 137 2.2E-16 T 29-03-2018 IPR003711 CarD-like/TRCF domain GBCGDNIH2_RS09645 21a8fb517a674cf174e810a890e2a229 216 SMART SM01058 28 138 8.1E-30 T 29-03-2018 IPR003711 CarD-like/TRCF domain GBCGDNIH2_RS06110 1c0805f5a602552a5b6dd4c038506bde 278 SUPERFAMILY SSF56281 27 212 1.13E-9 T 29-03-2018 IPR001279 Metallo-beta-lactamase GBCGDNIH2_RS06110 1c0805f5a602552a5b6dd4c038506bde 278 Gene3D G3DSA:3.60.15.10 17 274 2.0E-10 T 29-03-2018 IPR001279 Metallo-beta-lactamase GBCGDNIH2_RS00065 8067f235373747b435c34cbd860702d4 118 SUPERFAMILY SSF52833 9 112 2.24E-22 T 29-03-2018 IPR012336 Thioredoxin-like fold GBCGDNIH2_RS00065 8067f235373747b435c34cbd860702d4 118 Gene3D G3DSA:3.40.30.10 9 118 1.5E-21 T 29-03-2018 GBCGDNIH2_RS10695 e1deec3e7b0db21eaf890981098c30ce 501 Pfam PF00474 Sodium:solute symporter family 39 416 5.5E-15 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 GBCGDNIH2_RS04820 6bdbaedc513fb967af10d4895c31c54c 133 Pfam PF13554 Bacteriophage related domain of unknown function 7 125 5.4E-12 T 29-03-2018 IPR025395 Protein of unknown function DUF4128 GBCGDNIH2_RS04655 45f44c6f9076f441b68d9fffbd16e9dc 137 Pfam PF07750 GcrA cell cycle regulator 44 129 6.5E-10 T 29-03-2018 IPR011681 GcrA cell cycle regulator GBCGDNIH2_RS06530 06dc01ac444c9cc1ee36292b2da3a17f 488 Pfam PF04966 Carbohydrate-selective porin, OprB family 127 488 4.6E-70 T 29-03-2018 IPR007049 Carbohydrate-selective porin OprB GO:0005215|GO:0006810|GO:0016021 GBCGDNIH2_RS05105 80fe0b818017902ce04bbeb3ba217e48 280 Pfam PF01148 Cytidylyltransferase family 21 270 2.0E-54 T 29-03-2018 GBCGDNIH2_RS05105 80fe0b818017902ce04bbeb3ba217e48 280 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 230 256 - T 29-03-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 GBCGDNIH2_RS09220 868d82810254f7de0527988d766fe9be 145 Pfam PF07963 Prokaryotic N-terminal methylation motif 15 35 3.9E-5 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site GBCGDNIH2_RS02980 a7d3b056f22f51070e7c96fc27960632 937 Pfam PF05170 AsmA family 26 242 5.2E-9 T 29-03-2018 IPR007844 AsmA GBCGDNIH2_RS04785 79622d17380e735615eb4788c7727184 579 Pfam PF04860 Phage portal protein 48 372 2.1E-72 T 29-03-2018 IPR006944 Bacteriophage/Gene transfer agent portal protein GBCGDNIH2_RS04785 79622d17380e735615eb4788c7727184 579 TIGRFAM TIGR01537 portal_HK97: phage portal protein, HK97 family 41 378 1.3E-56 T 29-03-2018 IPR006427 Phage portal protein, HK97 GBCGDNIH2_RS09540 bc5104d78692503a5498bd9b04cd7872 548 Pfam PF13520 Amino acid permease 32 486 3.2E-87 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 GBCGDNIH2_RS09540 bc5104d78692503a5498bd9b04cd7872 548 PIRSF PIRSF006060 11 526 2.3E-81 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 GBCGDNIH2_RS10670 67bd70cf7341fab8655483789dbe0de5 166 Pfam PF03692 Putative zinc- or iron-chelating domain 25 93 2.1E-8 T 29-03-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein GBCGDNIH2_RS10670 67bd70cf7341fab8655483789dbe0de5 166 Hamap MF_00676 UPF0260 protein YcgN [ycgN]. 3 146 41.718 T 29-03-2018 IPR008228 Uncharacterised conserved protein UCP006173 GBCGDNIH2_RS10670 67bd70cf7341fab8655483789dbe0de5 166 PIRSF PIRSF006173 1 146 9.4E-67 T 29-03-2018 IPR008228 Uncharacterised conserved protein UCP006173 GBCGDNIH2_RS07590 73edebdf29a1323109c347f8122bc867 323 Pfam PF02470 MlaD protein 68 136 3.7E-8 T 29-03-2018 IPR003399 Mce/MlaD GBCGDNIH2_RS07590 73edebdf29a1323109c347f8122bc867 323 Gene3D G3DSA:1.10.287.950 179 301 6.3E-4 T 29-03-2018 GBCGDNIH2_RS08360 6f53f1c686d54ceebc4c974bfea4df92 316 PIRSF PIRSF029202 5 316 6.9E-90 T 29-03-2018 IPR020049 Protein of unknown function DUF2184 GBCGDNIH2_RS08360 6f53f1c686d54ceebc4c974bfea4df92 316 Pfam PF09950 Uncharacterized protein conserved in bacteria (DUF2184) 66 316 1.2E-86 T 29-03-2018 IPR020049 Protein of unknown function DUF2184 GBCGDNIH2_RS07375 b524b988f146964c8fabc4ab82764099 98 Gene3D G3DSA:1.10.10.10 7 77 2.3E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS09100 00cd8dd30688afcacd083689516a2b39 182 Pfam PF02470 MlaD protein 37 114 1.3E-20 T 29-03-2018 IPR003399 Mce/MlaD GBCGDNIH2_RS09100 00cd8dd30688afcacd083689516a2b39 182 TIGRFAM TIGR04430 OM_asym_MlaD: outer membrane lipid asymmetry maintenance protein MlaD 4 145 1.2E-46 T 29-03-2018 IPR030970 Probable phospholipid ABC transporter-binding protein MlaD GO:0015914 GBCGDNIH2_RS05060 658534945a385bda9c0d0f9e213153ef 405 Pfam PF00999 Sodium/hydrogen exchanger family 19 378 5.6E-34 T 29-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 GBCGDNIH2_RS05060 658534945a385bda9c0d0f9e213153ef 405 Gene3D G3DSA:1.20.91.10 237 321 5.4E-15 T 29-03-2018 GBCGDNIH2_RS04455 1e624542f2f6d000240829aa37595c23 579 Gene3D G3DSA:3.40.50.300 35 458 1.6E-26 T 29-03-2018 GBCGDNIH2_RS04455 1e624542f2f6d000240829aa37595c23 579 SUPERFAMILY SSF52540 18 395 1.18E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase GBCGDNIH2_RS04455 1e624542f2f6d000240829aa37595c23 579 Pfam PF05872 Bacterial protein of unknown function (DUF853) 32 576 6.2E-216 T 29-03-2018 IPR033186 Helicase HerA-like C-terminal GBCGDNIH2_RS03645 7349c959f440560d960fbeaeeef0e219 483 Pfam PF04966 Carbohydrate-selective porin, OprB family 105 483 8.2E-74 T 29-03-2018 IPR007049 Carbohydrate-selective porin OprB GO:0005215|GO:0006810|GO:0016021 GBCGDNIH2_RS00855 66dd77aa2ebc035debbfb53f97e63971 438 Pfam PF04932 O-Antigen ligase 205 360 1.1E-11 T 29-03-2018 IPR007016 O-antigen ligase-related GBCGDNIH2_RS01945 26ef708240221c4b2e13049944cbd1c3 257 Pfam PF01027 Inhibitor of apoptosis-promoting Bax1 27 250 1.8E-55 T 29-03-2018 IPR006214 Bax inhibitor 1-related GBCGDNIH2_RS07715 bc3ec85b060af93aae7d52a913c5af34 145 Pfam PF04138 GtrA-like protein 22 144 3.9E-21 T 29-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 GBCGDNIH2_RS05155 e7617e71af96c8c163ea8a424084d010 475 Gene3D G3DSA:3.40.50.300 22 381 1.5E-4 T 29-03-2018 GBCGDNIH2_RS05155 e7617e71af96c8c163ea8a424084d010 475 PIRSF PIRSF019381 1 475 2.3E-158 T 29-03-2018 IPR007413 Protein of unknown function DUF463, YcjX-like protein GBCGDNIH2_RS05155 e7617e71af96c8c163ea8a424084d010 475 Pfam PF04317 YcjX-like family, DUF463 25 475 1.9E-128 T 29-03-2018 IPR007413 Protein of unknown function DUF463, YcjX-like protein GBCGDNIH2_RS01995 41846c55b384b21844f0dccdb3db0ca3 151 Pfam PF05232 Chlorhexidine efflux transporter 8 71 1.9E-20 T 29-03-2018 IPR007896 Chlorhexidine efflux transporter GBCGDNIH2_RS01995 41846c55b384b21844f0dccdb3db0ca3 151 Pfam PF05232 Chlorhexidine efflux transporter 79 140 2.3E-23 T 29-03-2018 IPR007896 Chlorhexidine efflux transporter GBCGDNIH2_RS03730 18aedcb90a01bc1170a6bf854a98cf27 192 Pfam PF02417 Chromate transporter 16 174 1.9E-25 T 29-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 GBCGDNIH2_RS03970 a41b77fb38fb26676f64b2c50f0085fd 282 Pfam PF01874 ATP:dephospho-CoA triphosphoribosyl transferase 8 270 6.9E-63 T 29-03-2018 IPR002736 Triphosphoribosyl-dephospho-CoA protein GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 GBCGDNIH2_RS03250 fca6910822e0a7dce39af4c5d2ff440e 121 Pfam PF16998 17 kDa outer membrane surface antigen 58 119 2.1E-8 T 29-03-2018 IPR032635 Surface antigen domain GBCGDNIH2_RS04035 650b3374cece73cb25b2fe043b4c2a8e 236 Pfam PF08856 Protein of unknown function (DUF1826) 45 222 3.5E-46 T 29-03-2018 IPR014955 Protein of unknown function DUF1826 GBCGDNIH2_RS06480 1ab017ecc22dfdb8925265b33922cef2 662 Pfam PF09822 ABC-type uncharacterized transport system 60 337 6.7E-66 T 29-03-2018 IPR019196 ABC-type uncharacterised transport system Reactome: R-HSA-5610787|Reactome: R-HSA-5620924 GBCGDNIH2_RS06480 1ab017ecc22dfdb8925265b33922cef2 662 Gene3D G3DSA:3.40.50.880 231 439 2.2E-4 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like GBCGDNIH2_RS12640 22530da34da6a22bb9ccea93ed8a3c99 383 Gene3D G3DSA:2.40.70.10 73 198 5.7E-5 T 29-03-2018 IPR021109 Aspartic peptidase domain GBCGDNIH2_RS05925 4a6e93b7ec688e1587ddeb5bfc77d9ed 303 Pfam PF01062 Bestrophin, RFP-TM, chloride channel 7 281 6.1E-58 T 29-03-2018 IPR021134 Bestrophin/UPF0187 Reactome: R-HSA-2672351 GBCGDNIH2_RS01530 4c2246802cb9391b1595cbc80d16f605 269 Pfam PF10127 Predicted nucleotidyltransferase 15 264 8.4E-81 T 29-03-2018 IPR018775 Nucleotidyltransferase, predicted GBCGDNIH2_RS01530 4c2246802cb9391b1595cbc80d16f605 269 Gene3D G3DSA:3.30.460.10 4 186 2.9E-5 T 29-03-2018 GBCGDNIH2_RS00690 d3e44770d7600c82d0a94fe092275cd2 419 Pfam PF09898 Uncharacterized protein conserved in bacteria (DUF2125) 74 406 1.6E-17 T 29-03-2018 IPR018666 Protein of unknown function DUF2125 GBCGDNIH2_RS00220 946ec03b1ce9ef98dae7418cc836b725 550 Pfam PF05425 Copper resistance protein D 190 289 4.1E-19 T 29-03-2018 IPR008457 Copper resistance protein D GO:0016021 GBCGDNIH2_RS05475 bea1244e221726e7cd94fac8d3e6fed4 180 Pfam PF02620 Uncharacterized ACR, COG1399 62 174 2.7E-21 T 29-03-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD GBCGDNIH2_RS06980 fa2e264cf275a19fb8b99f08639a027f 43 Pfam PF05489 Phage Tail Protein X 17 42 7.0E-6 T 29-03-2018 IPR008861 Phage Tail Protein X-like GBCGDNIH2_RS01665 4ce3f525d0ee83fa90d040878fb7b098 245 Pfam PF06912 Protein of unknown function (DUF1275) 23 232 1.5E-28 T 29-03-2018 IPR010699 Protein of unknown function DUF1275 GBCGDNIH2_RS07565 c2a94524747302bbf099b49c4df6ea8a 464 TIGRFAM TIGR01358 DAHP_synth_II: 3-deoxy-7-phosphoheptulonate synthase 14 454 4.5E-215 T 29-03-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 GBCGDNIH2_RS07565 c2a94524747302bbf099b49c4df6ea8a 464 SUPERFAMILY SSF51569 11 453 8.79E-204 T 29-03-2018 GBCGDNIH2_RS07565 c2a94524747302bbf099b49c4df6ea8a 464 Gene3D G3DSA:3.20.20.70 242 387 2.6E-8 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 GBCGDNIH2_RS07565 c2a94524747302bbf099b49c4df6ea8a 464 Pfam PF01474 Class-II DAHP synthetase family 14 449 2.9E-203 T 29-03-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 GBCGDNIH2_RS06655 bba8a79e8ab9c8e87b295a103f703c32 184 Pfam PF12276 Protein of unknown function (DUF3617) 54 180 8.8E-9 T 29-03-2018 IPR022061 Protein of unknown function DUF3617 GBCGDNIH2_RS04735 494206bcc001e33bb8f7b6241e7e793e 260 Pfam PF07505 Protein of unknown function (DUF5131) 3 253 1.5E-96 T 29-03-2018 IPR011101 Protein of unknown function DUF5131 GBCGDNIH2_RS12590 217f2a0f84955ee50e05c034c8410513 525 Pfam PF01384 Phosphate transporter family 64 512 6.7E-80 T 29-03-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 GBCGDNIH2_RS06280 56d6eafe4a8171712bc54f2a60fa1a49 123 Pfam PF13788 Domain of unknown function (DUF4180) 10 119 3.5E-37 T 29-03-2018 IPR025438 Domain of unknown function DUF4180 GBCGDNIH2_RS06105 780aef79761bb6c81749fb60f7c87eda 176 Pfam PF04982 HPP family 43 158 1.3E-34 T 29-03-2018 IPR007065 HPP GBCGDNIH2_RS11285 054599647f8624ba321a57caa0646e38 690 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 33 315 1.1E-8 T 29-03-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD GBCGDNIH2_RS10530 cf45a57f49424226e5e3be8be84392f4 111 Pfam PF06305 Lipopolysaccharide assembly protein A domain 20 84 3.8E-14 T 29-03-2018 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 GBCGDNIH2_RS11620 2ab8f7a682c1b009ac81c2c39ee66453 306 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 14 290 8.2E-43 T 29-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 GBCGDNIH2_RS11790 3085dd8fed07635ab320b1350f160274 136 Pfam PF04138 GtrA-like protein 7 127 1.3E-19 T 29-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 GBCGDNIH2_RS02420 9ebed3942bd5619fac2cd8664bec3b96 196 Pfam PF02674 Colicin V production protein 4 143 3.1E-31 T 29-03-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 GBCGDNIH2_RS00840 bf432f3a2289f09d30fa4668ec8d25ca 129 Pfam PF04241 Protein of unknown function (DUF423) 19 105 3.5E-19 T 29-03-2018 IPR006696 Protein of unknown function DUF423 GBCGDNIH2_RS07910 267396c8837418a6db406fc03bb95ac1 504 Pfam PF04966 Carbohydrate-selective porin, OprB family 122 488 2.5E-42 T 29-03-2018 IPR007049 Carbohydrate-selective porin OprB GO:0005215|GO:0006810|GO:0016021 GBCGDNIH2_RS08070 005f6ce88dc66e7cc3be318617388a8f 219 Gene3D G3DSA:1.10.10.10 2 49 0.0019 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain GBCGDNIH2_RS07045 50c4dbab8a5314eb7fe9d9fd622c9c49 149 Pfam PF05425 Copper resistance protein D 46 142 2.3E-8 T 29-03-2018 IPR008457 Copper resistance protein D GO:0016021 GBCGDNIH2_RS00660 02259738ee7049c87f90b425afd10da2 910 Pfam PF13779 Domain of unknown function (DUF4175) 27 908 4.5E-192 T 29-03-2018 IPR012683 Conserved hypothetical protein CHP02302, transmembrane GBCGDNIH2_RS01670 2e671b95365a62b084033f622cd165f5 588 SUPERFAMILY SSF51120 368 572 2.09E-7 T 29-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal GBCGDNIH2_RS07365 6b08a2c2756c19344cbc1bc5aff1926c 485 Pfam PF09481 CRISPR-associated protein Cse1 (CRISPR_cse1) 4 425 1.3E-63 T 29-03-2018 IPR013381 CRISPR-associated protein Cse1 GBCGDNIH2_RS07365 6b08a2c2756c19344cbc1bc5aff1926c 485 TIGRFAM TIGR02547 casA_cse1: CRISPR type I-E/ECOLI-associated protein CasA/Cse1 4 457 3.0E-52 T 29-03-2018 IPR013381 CRISPR-associated protein Cse1 GBCGDNIH2_RS08575 04c61a54022ef69425f4f95622cb62bd 329 Gene3D G3DSA:1.20.120.20 207 306 0.23 T 29-03-2018 GBCGDNIH2_RS08575 04c61a54022ef69425f4f95622cb62bd 329 Gene3D G3DSA:1.20.120.20 66 206 5.9E-4 T 29-03-2018 GBCGDNIH2_RS08385 4695988cdcdecbc4ab5d0bf2dd6073a3 224 Pfam PF03592 Terminase small subunit 47 196 5.9E-13 T 29-03-2018 IPR005335 Terminase small subunit GO:0006323 GBCGDNIH2_RS11660 9868ceee68e5a0cabf68c17d94169db5 230 Pfam PF02104 SURF1 family 16 214 4.4E-30 T 29-03-2018 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GBCGDNIH2_RS02520 984f61780c8de22a83836ed072350cf8 586 Pfam PF03169 OPT oligopeptide transporter protein 311 558 1.2E-7 T 29-03-2018 IPR004813 Oligopeptide transporter, OPT superfamily GO:0055085 GBCGDNIH2_RS02520 984f61780c8de22a83836ed072350cf8 586 Pfam PF03169 OPT oligopeptide transporter protein 51 209 2.2E-9 T 29-03-2018 IPR004813 Oligopeptide transporter, OPT superfamily GO:0055085 GBCGDNIH2_RS02275 92ca51e412b23a9f0b871bab1619918a 183 Pfam PF02698 DUF218 domain 14 156 6.0E-21 T 29-03-2018 IPR003848 Domain of unknown function DUF218 GBCGDNIH2_RS02275 92ca51e412b23a9f0b871bab1619918a 183 Gene3D G3DSA:3.40.50.620 7 142 2.4E-21 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GBCGDNIH2_RS03950 2c693960910666d06a72ef71c009a771 133 Pfam PF07007 Lysozyme inhibitor LprI 26 117 2.3E-22 T 29-03-2018 IPR009739 Lysozyme inhibitor LprI, N-terminal GBCGDNIH2_RS11875 ca16867723a43d1168bdc79f22009a62 301 Pfam PF09976 Tetratricopeptide repeat-like domain 101 222 3.2E-11 T 29-03-2018 IPR018704 Tetratricopeptide repeat-like domain Reactome: R-HSA-192823|Reactome: R-HSA-381038|Reactome: R-HSA-381426|Reactome: R-HSA-6798695|Reactome: R-HSA-8957275 GBCGDNIH2_RS04075 b2b7ae99f0377548ef76786629b5cb34 192 Pfam PF09335 SNARE associated Golgi protein 52 154 3.1E-11 T 29-03-2018 IPR032816 SNARE associated Golgi protein GBCGDNIH2_RS10745 630a5e65f4f521c5df82e27ca560d921 282 Pfam PF04402 Protein of unknown function (DUF541) 61 246 5.7E-27 T 29-03-2018 IPR007497 Protein of unknown function DUF541 GBCGDNIH2_RS05630 57e61cf4dd587e461d81a59f37a7d3e5 224 Pfam PF03729 Short repeat of unknown function (DUF308) 59 125 2.9E-7 T 29-03-2018 IPR005325 Protein of unknown function DUF308, membrane GBCGDNIH2_RS05630 57e61cf4dd587e461d81a59f37a7d3e5 224 Pfam PF03729 Short repeat of unknown function (DUF308) 116 187 2.6E-9 T 29-03-2018 IPR005325 Protein of unknown function DUF308, membrane GBCGDNIH2_RS06725 fa844c0a5dbf2328341a9bb5e0ebe092 401 Pfam PF05987 Bacterial protein of unknown function (DUF898) 27 393 1.9E-83 T 29-03-2018 IPR010295 Protein of unknown function DUF898 GBCGDNIH2_RS02105 acc49fcda7d0975a0daaafdc31e29fa6 391 Pfam PF01594 AI-2E family transporter 46 369 3.8E-32 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like GBCGDNIH2_RS04450 529086bc78cfd593c78e8f1b6a7c9030 257 Pfam PF01925 Sulfite exporter TauE/SafE 11 251 2.7E-47 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 GBCGDNIH2_RS01310 9bb0e41fd5a4abb456a5c9368f03d9b2 114 Gene3D G3DSA:3.40.30.10 13 100 1.1E-4 T 29-03-2018 GBCGDNIH2_RS08080 64e5a885d26556be902cfc38ab0de6a9 166 Pfam PF06114 IrrE N-terminal-like domain 60 163 6.9E-21 T 29-03-2018 IPR010359 IrrE N-terminal-like domain GBCGDNIH2_RS05015 8de64aef0311c153bf151cbab112960c 177 Pfam PF02643 Uncharacterized ACR, COG1430 51 154 2.9E-30 T 29-03-2018 IPR003795 Protein of unknown function DUF192