locus-tag	class	description
AY555_RS00050	COG1684	flagellar biosynthetic protein fliR
AY555_RS00055	COG1987	bacterial-type flagellum assembly
AY555_RS00060	COG1677	Flagellar hook-basal body complex protein FliE
AY555_RS00065	COG1558	bacterial-type flagellum-dependent cell motility
AY555_RS00075	COG2257	FlhB HrpN YscU SpaS Family
AY555_RS00090	COG1338	Plays a role in the flagellum-specific transport system
AY555_RS00095	COG1522	sequence-specific DNA binding
AY555_RS00105	COG1360	Flagellar Motor Protein
AY555_RS00120	COG0745	RESPONSE REGULATOR receiver
AY555_RS00145	COG4786	Flagellar basal body rod
AY555_RS00150	COG4786	Flagellar basal body rod
AY555_RS00155	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
AY555_RS00160	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AY555_RS00180	COG1706	bacterial-type flagellum-dependent cell motility
AY555_RS00220	COG5443	negative regulation of bacterial-type flagellum assembly
AY555_RS00225	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AY555_RS00235	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AY555_RS00245	COG2855	membrane
AY555_RS00250	COG1196	nuclear chromosome segregation
AY555_RS00250	COG0741	lytic transglycosylase activity
AY555_RS00250	COG0739	heme binding
AY555_RS00255	COG1573	uracil-dna glycosylase
AY555_RS00290	COG1918	ferrous iron import across plasma membrane
AY555_RS00295	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AY555_RS00345	COG1760	l-serine dehydratase
AY555_RS00350	COG0814	amino acid
AY555_RS00360	COG2202	Pas domain
AY555_RS00360	COG2205	protein histidine kinase activity
AY555_RS00365	COG1612	heme a metabolic process
AY555_RS00380	COG1380	Effector of murein hydrolase LrgA
AY555_RS00385	COG1346	cytolysis
AY555_RS00390	COG3040	lipid binding
AY555_RS00395	COG0857	belongs to the CobB CobQ family
AY555_RS00395	COG0280	phosphate acetyltransferase
AY555_RS00400	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AY555_RS00405	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AY555_RS00420	COG3279	Response regulator of the LytR AlgR family
AY555_RS00425	COG3275	phosphorelay sensor kinase activity
AY555_RS00440	COG0277	FAD linked oxidase domain protein
AY555_RS00450	COG0009	L-threonylcarbamoyladenylate synthase
AY555_RS00455	COG1218	3'(2'),5'-bisphosphate nucleotidase
AY555_RS00470	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AY555_RS00475	COG1960	acyl-CoA dehydrogenase activity
AY555_RS00490	COG0795	lipopolysaccharide-transporting ATPase activity
AY555_RS00500	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AY555_RS00505	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AY555_RS00510	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AY555_RS00520	COG1561	YicC-like family, N-terminal region
AY555_RS00565	COG1160	GTP binding
AY555_RS00575	COG0598	Magnesium transport protein CorA
AY555_RS00590	COG0167	dihydroorotate dehydrogenase activity
AY555_RS00605	COG0123	including yeast histone deacetylase and acetoin utilization protein
AY555_RS00610	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AY555_RS00615	COG1040	competence protein
AY555_RS00625	COG1073	alpha beta
AY555_RS00625	COG2226	methyltransferase
AY555_RS00635	COG0024	Methionine aminopeptidase
AY555_RS00640	COG2003	Belongs to the UPF0758 family
AY555_RS00655	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AY555_RS00675	COG1686	Belongs to the peptidase S11 family
AY555_RS00680	COG0033	Phosphoglucomutase
AY555_RS00685	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AY555_RS00735	COG0745	RESPONSE REGULATOR receiver
AY555_RS00755	COG1960	acyl-CoA dehydrogenase activity
AY555_RS00760	COG0288	reversible hydration of carbon dioxide
AY555_RS00765	COG0183	Belongs to the thiolase family
AY555_RS00795	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AY555_RS00800	COG2917	probably involved in intracellular septation
AY555_RS00820	COG0564	pseudouridine synthase activity
AY555_RS00825	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AY555_RS00830	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AY555_RS00835	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AY555_RS00840	COG0203	ribosomal protein L17
AY555_RS00855	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AY555_RS00865	COG0201	protein transport
AY555_RS00870	COG0200	Binds to the 23S rRNA
AY555_RS00875	COG1841	ribosomal large subunit assembly
AY555_RS00880	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AY555_RS00890	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AY555_RS00895	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AY555_RS00900	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AY555_RS00905	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AY555_RS00910	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AY555_RS00920	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AY555_RS00925	COG0255	Belongs to the universal ribosomal protein uL29 family
AY555_RS00930	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AY555_RS00935	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AY555_RS00945	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AY555_RS00950	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AY555_RS00955	COG0089	rRNA binding
AY555_RS00960	COG0088	Forms part of the polypeptide exit tunnel
AY555_RS00965	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AY555_RS00975	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AY555_RS00985	COG0049	tRNA binding
AY555_RS00995	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AY555_RS01000	COG0085	RNA polymerase activity
AY555_RS01005	COG0222	ribosome binding
AY555_RS01010	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AY555_RS01020	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AY555_RS01030	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AY555_RS01040	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AY555_RS01055	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AY555_RS01095	COG0425	Belongs to the sulfur carrier protein TusA family
AY555_RS01100	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AY555_RS01110	COG1846	Transcriptional regulator
AY555_RS01125	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AY555_RS01130	COG1671	Belongs to the UPF0178 family
AY555_RS01140	COG0006	proline dipeptidase activity
AY555_RS01150	COG2264	protein methyltransferase activity
AY555_RS01160	COG0210	DNA helicase
AY555_RS01165	COG1410	methionine synthase
AY555_RS01165	COG0646	methionine synthase
AY555_RS01175	COG2226	methyltransferase
AY555_RS01235	COG2971	BadF BadG BcrA BcrD
AY555_RS01240	COG0488	(ABC) transporter
AY555_RS01250	COG0183	Belongs to the thiolase family
AY555_RS01265	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AY555_RS01270	COG0358	DNA primase activity
AY555_RS01285	COG0505	Belongs to the CarA family
AY555_RS01290	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AY555_RS01295	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AY555_RS01305	COG1522	sequence-specific DNA binding
AY555_RS01310	COG0450	alkyl hydroperoxide reductase
AY555_RS01315	COG0492	ferredoxin-NADP+ reductase activity
AY555_RS01350	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AY555_RS01365	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AY555_RS01370	COG1605	Chorismate mutase
AY555_RS01370	COG0077	Prephenate dehydratase
AY555_RS01380	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AY555_RS01385	COG0159	tryptophan synthase activity
AY555_RS01435	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AY555_RS01450	COG1764	response to oxidative stress
AY555_RS01455	COG0538	isocitrate dehydrogenase activity
AY555_RS01465	COG3909	cytochrome
AY555_RS01475	COG0071	Belongs to the small heat shock protein (HSP20) family
AY555_RS01480	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AY555_RS01485	COG2205	protein histidine kinase activity
AY555_RS01490	COG0745	RESPONSE REGULATOR receiver
AY555_RS01495	COG1846	Transcriptional regulator
AY555_RS01500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AY555_RS01515	COG3842	ATPase activity
AY555_RS01520	COG1176	ABC-type spermidine putrescine transport system, permease component I
AY555_RS01525	COG1177	transmembrane transport
AY555_RS01530	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AY555_RS01540	COG3045	CreA protein
AY555_RS01550	COG1028	Short-chain dehydrogenase reductase Sdr
AY555_RS01555	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AY555_RS01565	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AY555_RS01570	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AY555_RS01620	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AY555_RS01625	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AY555_RS01630	COG4536	flavin adenine dinucleotide binding
AY555_RS01645	COG0228	four-way junction DNA binding
AY555_RS01650	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AY555_RS01655	COG0336	Belongs to the RNA methyltransferase TrmD family
AY555_RS01660	COG0335	large ribosomal subunit rRNA binding
AY555_RS01670	COG2239	Acts as a magnesium transporter
AY555_RS01680	COG0271	Belongs to the BolA IbaG family
AY555_RS01685	COG0484	heat shock protein binding
AY555_RS01705	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AY555_RS01740	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AY555_RS01750	COG0330	HflC and HflK could
AY555_RS01755	COG0489	protein tyrosine kinase activity
AY555_RS01765	COG1760	l-serine dehydratase
AY555_RS01770	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AY555_RS01785	COG0135	phosphoribosylanthranilate isomerase activity
AY555_RS01810	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AY555_RS01815	COG1132	(ABC) transporter
AY555_RS01825	COG1519	Transferase
AY555_RS01830	COG1663	tetraacyldisaccharide 4'-kinase activity
AY555_RS01840	COG2030	dehydratase
AY555_RS01850	COG0500	methyltransferase
AY555_RS01860	COG0590	tRNA wobble adenosine to inosine editing
AY555_RS01865	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AY555_RS01870	COG1187	pseudouridine synthase activity
AY555_RS01875	COG0742	ribosomal rna small subunit methyltransferase
AY555_RS01880	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AY555_RS01885	COG1396	sequence-specific DNA binding
AY555_RS01915	COG2113	Glycine betaine
AY555_RS01920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AY555_RS01930	COG0765	amino acid transport
AY555_RS01940	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AY555_RS01945	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AY555_RS01950	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AY555_RS01970	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AY555_RS01975	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AY555_RS01980	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AY555_RS01990	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AY555_RS01995	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AY555_RS02000	COG0799	negative regulation of ribosome biogenesis
AY555_RS02040	COG0477	Major facilitator Superfamily
AY555_RS02045	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AY555_RS02050	COG3300	MHYT domain
AY555_RS02050	COG5001	Diguanylate cyclase
AY555_RS02070	COG0126	phosphoglycerate kinase activity
AY555_RS02090	COG2205	protein histidine kinase activity
AY555_RS02095	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
AY555_RS02100	COG2137	regulation of response to DNA damage stimulus
AY555_RS02105	COG0842	Transport permease protein
AY555_RS02110	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AY555_RS02120	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AY555_RS02170	COG0302	gtp cyclohydrolase
AY555_RS02195	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AY555_RS02205	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AY555_RS02210	COG0602	queuosine metabolic process
AY555_RS02220	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AY555_RS02260	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AY555_RS02265	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AY555_RS02270	COG1278	Cold shock
AY555_RS02280	COG0606	chelatase, subunit chli
AY555_RS02290	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AY555_RS02300	COG0612	Peptidase, M16
AY555_RS02305	COG0745	RESPONSE REGULATOR receiver
AY555_RS02320	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AY555_RS02325	COG0471	metal ion transport
AY555_RS02325	COG3273	potassium ion transport
AY555_RS02340	COG4166	transmembrane transport
AY555_RS02345	COG4174	ABC transporter (Permease)
AY555_RS02350	COG4239	(ABC) transporter, permease
AY555_RS02355	COG4172	Belongs to the ABC transporter superfamily
AY555_RS02360	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AY555_RS02370	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AY555_RS02375	COG2358	TRAP transporter, solute receptor (TAXI family
AY555_RS02385	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AY555_RS02390	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AY555_RS02395	COG0072	phenylalanine-tRNA ligase activity
AY555_RS02410	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AY555_RS02415	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AY555_RS02420	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AY555_RS02435	COG0784	Response regulator, receiver
AY555_RS02435	COG2198	Histidine kinase
AY555_RS02435	COG5002	protein histidine kinase activity
AY555_RS02445	COG1194	a g-specific adenine glycosylase
AY555_RS02455	COG2884	Cell division ATP-binding protein ftsE
AY555_RS02475	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AY555_RS02475	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AY555_RS02485	COG1131	(ABC) transporter
AY555_RS02495	COG5002	protein histidine kinase activity
AY555_RS02500	COG0312	modulator of DNA gyrase
AY555_RS02510	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AY555_RS02520	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AY555_RS02525	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AY555_RS02540	COG0181	hydroxymethylbilane synthase activity
AY555_RS02545	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AY555_RS02560	COG0250	Participates in transcription elongation, termination and antitermination
AY555_RS02565	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AY555_RS02565	COG0662	Cupin 2, conserved barrel domain protein
AY555_RS02570	COG0438	transferase activity, transferring glycosyl groups
AY555_RS02575	COG0367	asparagine synthase
AY555_RS02580	COG0367	asparagine synthase
AY555_RS02595	COG1215	transferase activity, transferring glycosyl groups
AY555_RS02600	COG0438	transferase activity, transferring glycosyl groups
AY555_RS02615	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AY555_RS02660	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AY555_RS02665	COG0539	negative regulation of cytoplasmic translation
AY555_RS02670	COG0776	regulation of translation
AY555_RS02680	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AY555_RS02680	COG0475	glutathione-regulated potassium exporter activity
AY555_RS02755	COG1525	nuclease
AY555_RS02760	COG3941	tape measure
AY555_RS02775	COG4386	tail sheath protein
AY555_RS02815	COG4695	Portal protein
AY555_RS02820	COG1802	Transcriptional regulator
AY555_RS02820	COG4626	Terminase
AY555_RS02865	COG0358	DNA primase activity
AY555_RS02960	COG1678	Uncharacterized ACR, COG1678
AY555_RS02980	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AY555_RS02985	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AY555_RS03005	COG2902	Dehydrogenase
AY555_RS03020	COG1660	Displays ATPase and GTPase activities
AY555_RS03025	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AY555_RS03025	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AY555_RS03035	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AY555_RS03040	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AY555_RS03045	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AY555_RS03050	COG1137	ATPase activity
AY555_RS03080	COG0702	epimerase
AY555_RS03085	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AY555_RS03100	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AY555_RS03115	COG0730	response to heat
AY555_RS03120	COG0180	Tryptophanyl-tRNA synthetase
AY555_RS03125	COG0728	peptidoglycan biosynthetic process
AY555_RS03130	COG0670	Belongs to the BI1 family
AY555_RS03140	COG4181	ATPase activity
AY555_RS03160	COG0242	peptide deformylase activity
AY555_RS03165	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AY555_RS03170	COG0101	tRNA pseudouridine synthase activity
AY555_RS03175	COG0659	secondary active sulfate transmembrane transporter activity
AY555_RS03200	COG4797	methyltransferase
AY555_RS03200	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AY555_RS03205	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AY555_RS03210	COG3264	Mechanosensitive ion channel
AY555_RS03210	COG1196	nuclear chromosome segregation
AY555_RS03225	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AY555_RS03235	COG1131	(ABC) transporter
AY555_RS03250	COG4235	cytochrome complex assembly
AY555_RS03255	COG3088	subunit of a heme lyase
AY555_RS03260	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AY555_RS03265	COG1138	Cytochrome C-type biogenesis protein
AY555_RS03270	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AY555_RS03280	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AY555_RS03290	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AY555_RS03295	COG0019	diaminopimelate decarboxylase activity
AY555_RS03300	COG2835	tetraacyldisaccharide 4'-kinase activity
AY555_RS03340	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AY555_RS03345	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AY555_RS03370	COG2983	Belongs to the UPF0260 family
AY555_RS03380	COG1999	signal sequence binding
AY555_RS03395	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AY555_RS03415	COG2154	pterin-4-alpha-carbinolamine dehydratase
AY555_RS03420	COG1067	ATP-dependent peptidase activity
AY555_RS03435	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AY555_RS03460	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AY555_RS03465	COG4942	peptidase
AY555_RS03470	COG0793	Belongs to the peptidase S41A family
AY555_RS03480	COG1051	belongs to the nudix hydrolase family
AY555_RS03515	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AY555_RS03525	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AY555_RS03550	COG1250	3-hydroxyacyl-CoA dehydrogenase
AY555_RS03570	COG1396	sequence-specific DNA binding
AY555_RS03580	COG0671	phosphoesterase, PA-phosphatase related
AY555_RS03585	COG0039	L-malate dehydrogenase activity
AY555_RS03595	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AY555_RS03605	COG0552	protein localization to endoplasmic reticulum
AY555_RS03610	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AY555_RS03615	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AY555_RS03630	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AY555_RS03645	COG0495	leucyl-tRNA aminoacylation
AY555_RS03665	COG0352	thiamine-phosphate diphosphorylase activity
AY555_RS03670	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AY555_RS03675	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AY555_RS03680	COG1420	regulation of RNA biosynthetic process
AY555_RS03695	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AY555_RS03700	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AY555_RS03705	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AY555_RS03710	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AY555_RS03720	COG3030	protein affecting phage T7 exclusion by the F plasmid
AY555_RS03735	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AY555_RS03745	COG3411	Ferredoxin
AY555_RS03750	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AY555_RS03755	COG0445	tRNA wobble uridine modification
AY555_RS03760	COG0357	Ribosomal RNA small subunit methyltransferase G
AY555_RS03775	COG0501	Belongs to the peptidase M48B family
AY555_RS03785	COG0138	bifunctional purine biosynthesis protein purh
AY555_RS03790	COG1396	sequence-specific DNA binding
AY555_RS03805	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AY555_RS03810	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AY555_RS03835	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AY555_RS03845	COG1981	membrane
AY555_RS03850	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AY555_RS03855	COG1393	Belongs to the ArsC family
AY555_RS03860	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AY555_RS03905	COG2942	2-epimerase
AY555_RS03935	COG1058	Belongs to the CinA family
AY555_RS03935	COG1546	Belongs to the CinA family
AY555_RS03970	COG4957	zinc ion binding
AY555_RS04015	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AY555_RS04020	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AY555_RS04025	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AY555_RS04030	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AY555_RS04035	COG1185	polyribonucleotide nucleotidyltransferase activity
AY555_RS04040	COG0584	glycerophosphoryl diester phosphodiesterase
AY555_RS04055	COG0534	Mate efflux family protein
AY555_RS04060	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AY555_RS04070	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AY555_RS04075	COG0756	dUTP diphosphatase activity
AY555_RS04090	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AY555_RS04100	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AY555_RS04115	COG2912	Transglutaminase-like superfamily
AY555_RS04130	COG5425	PFAM Usg family protein
AY555_RS04140	COG1074	ATP-dependent DNA helicase activity
AY555_RS04150	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AY555_RS04155	COG3178	'Phosphotransferase
AY555_RS04160	COG0802	atpase or kinase
AY555_RS04165	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AY555_RS04170	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AY555_RS04175	COG1396	sequence-specific DNA binding
AY555_RS04180	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AY555_RS04185	COG1253	flavin adenine dinucleotide binding
AY555_RS04195	COG1702	phosphate starvation-inducible protein PhoH
AY555_RS04205	COG0481	GTPase activity
AY555_RS04210	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
AY555_RS04225	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AY555_RS04235	COG0280	phosphate acetyltransferase
AY555_RS04235	COG0281	malic enzyme
AY555_RS04240	COG5002	protein histidine kinase activity
AY555_RS04245	COG0704	Plays a role in the regulation of phosphate uptake
AY555_RS04250	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AY555_RS04295	COG2274	protein secretion by the type I secretion system
AY555_RS04300	COG1132	(ABC) transporter
AY555_RS04305	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AY555_RS04315	COG4133	protoheme IX ABC transporter activity
AY555_RS04325	COG0583	DNA-binding transcription factor activity
AY555_RS04345	COG4106	trans-aconitate 2-methyltransferase activity
AY555_RS04350	COG2166	iron-sulfur cluster assembly
AY555_RS04360	COG0443	Heat shock 70 kDa protein
AY555_RS04365	COG0484	heat shock protein binding
AY555_RS04370	COG0840	transmembrane signaling receptor activity
AY555_RS04380	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AY555_RS04395	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AY555_RS04410	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AY555_RS04415	COG2226	methyltransferase
AY555_RS04420	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AY555_RS04430	COG1024	Enoyl-CoA hydratase
AY555_RS04445	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AY555_RS04495	COG0270	DNA (cytosine-5-)-methyltransferase activity
AY555_RS04500	COG3727	T/G mismatch-specific endonuclease activity
AY555_RS04520	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AY555_RS04580	COG0735	belongs to the Fur family
AY555_RS04585	COG1121	(ABC) transporter
AY555_RS04590	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AY555_RS04610	COG2223	nitrite transmembrane transporter activity
AY555_RS04615	COG1217	gtp-binding protein TYPA
AY555_RS04620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AY555_RS04635	COG0642	Histidine kinase
AY555_RS04640	COG0745	RESPONSE REGULATOR receiver
AY555_RS04645	COG2847	Copper chaperone PCu(A)C
AY555_RS04710	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AY555_RS04715	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AY555_RS04720	COG4558	Periplasmic binding protein
AY555_RS04725	COG3720	iron ion transport
AY555_RS04735	COG4206	TonB-dependent receptor
AY555_RS04750	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AY555_RS04760	COG0039	L-malate dehydrogenase activity
AY555_RS04765	COG0045	succinate-CoA ligase (ADP-forming) activity
AY555_RS04780	COG0508	dehydrogenase complex catalyzes the overall conversion of
AY555_RS04785	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AY555_RS04795	COG0783	Belongs to the Dps family
AY555_RS04800	COG4974	Belongs to the 'phage' integrase family
AY555_RS04810	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AY555_RS04830	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AY555_RS04880	COG1496	oxidoreductase activity
AY555_RS04890	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AY555_RS04895	COG0733	neurotransmitter:sodium symporter activity
AY555_RS04900	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AY555_RS04905	COG0193	aminoacyl-tRNA hydrolase activity
AY555_RS04910	COG0012	GTP binding
AY555_RS04920	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AY555_RS04935	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AY555_RS04975	COG4191	Histidine kinase
AY555_RS04975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AY555_RS04990	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
AY555_RS05000	COG1086	Polysaccharide biosynthesis protein
AY555_RS05005	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AY555_RS05010	COG2076	Multidrug Resistance protein
AY555_RS05020	COG2176	DNA-directed DNA polymerase activity
AY555_RS05025	COG0517	IMP dehydrogenase activity
AY555_RS05035	COG3162	membrane
AY555_RS05045	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AY555_RS05060	COG0343	queuine tRNA-ribosyltransferase activity
AY555_RS05065	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AY555_RS05090	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AY555_RS05095	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
AY555_RS05105	COG0151	Belongs to the GarS family
AY555_RS05110	COG1570	exodeoxyribonuclease VII activity
AY555_RS05135	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AY555_RS05140	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AY555_RS05185	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AY555_RS05190	COG2171	N-acyltransferase activity
AY555_RS05195	COG5001	Diguanylate cyclase
AY555_RS05195	COG4251	negative regulation of phosphorylation
AY555_RS05195	COG3706	GGDEF domain
AY555_RS05195	COG2203	Gaf domain
AY555_RS05210	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AY555_RS05215	COG0706	membrane insertase activity
AY555_RS05225	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AY555_RS05230	COG3278	Belongs to the heme-copper respiratory oxidase family
AY555_RS05245	COG2010	Cytochrome c
AY555_RS05250	COG0348	domain, Protein
AY555_RS05270	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AY555_RS05290	COG3572	ergothioneine biosynthetic process
AY555_RS05300	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AY555_RS05315	COG0287	Prephenate dehydrogenase
AY555_RS05330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AY555_RS05335	COG2860	membrane
AY555_RS05340	COG0196	riboflavin kinase activity
AY555_RS05345	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AY555_RS05350	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AY555_RS05360	COG0612	Peptidase, M16
AY555_RS05365	COG0612	Peptidase, M16
AY555_RS05370	COG0166	Belongs to the GPI family
AY555_RS05375	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AY555_RS05385	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AY555_RS05390	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AY555_RS05410	COG0714	Associated with various cellular activities
AY555_RS05420	COG0494	nUDIX hydrolase
AY555_RS05430	COG0617	tRNA 3'-terminal CCA addition
AY555_RS05435	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AY555_RS05440	COG1872	DUF167
AY555_RS05485	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AY555_RS05495	COG0583	DNA-binding transcription factor activity
AY555_RS05515	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AY555_RS05535	COG0459	protein refolding
AY555_RS05540	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AY555_RS05550	COG0463	Glycosyl transferase, family 2
AY555_RS05560	COG0840	transmembrane signaling receptor activity
AY555_RS05570	COG1396	sequence-specific DNA binding
AY555_RS05575	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AY555_RS05575	COG1199	ATP-dependent helicase activity
AY555_RS05580	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AY555_RS05680	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AY555_RS05685	COG3246	L-lysine catabolic process to acetate
AY555_RS05695	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AY555_RS05710	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AY555_RS05710	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AY555_RS05730	COG0488	(ABC) transporter
AY555_RS05735	COG0105	UTP biosynthetic process
AY555_RS05740	COG0436	Aminotransferase
AY555_RS05755	COG3012	SEC-C Motif Domain Protein
AY555_RS05800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AY555_RS05810	COG1028	Short-chain dehydrogenase reductase Sdr
AY555_RS05815	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AY555_RS05830	COG1127	ABC transporter
AY555_RS05835	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AY555_RS05840	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AY555_RS05845	COG0305	Participates in initiation and elongation during chromosome replication
AY555_RS05855	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AY555_RS05865	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AY555_RS05880	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AY555_RS05885	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AY555_RS05895	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AY555_RS05905	COG0259	pyridoxamine-phosphate oxidase activity
AY555_RS05910	COG0484	heat shock protein binding
AY555_RS05930	COG4251	negative regulation of phosphorylation
AY555_RS05935	COG2204	response regulator
AY555_RS05940	COG0560	Phosphoserine phosphatase
AY555_RS05940	COG3830	Belongs to the UPF0237 family
AY555_RS05975	COG0768	penicillin binding
AY555_RS05980	COG0772	Belongs to the SEDS family
AY555_RS06065	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AY555_RS06070	COG0497	DNA recombination
AY555_RS06075	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AY555_RS06090	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AY555_RS06095	COG0849	cell division
AY555_RS06100	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AY555_RS06110	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AY555_RS06115	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AY555_RS06130	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AY555_RS06135	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AY555_RS06145	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AY555_RS06165	COG2001	Belongs to the MraZ family
AY555_RS06185	COG0501	Belongs to the peptidase M48B family
AY555_RS06200	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AY555_RS06205	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AY555_RS06210	COG2011	ABC-type metal ion transport system permease component
AY555_RS06245	COG1530	ribonuclease E activity
AY555_RS06250	COG0482	sulfurtransferase activity
AY555_RS06265	COG1959	2 iron, 2 sulfur cluster binding
AY555_RS06270	COG1045	serine acetyltransferase
AY555_RS06280	COG2945	thiolester hydrolase activity
AY555_RS06295	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AY555_RS06305	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AY555_RS06305	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AY555_RS06310	COG0840	transmembrane signaling receptor activity
AY555_RS06315	COG0519	Catalyzes the synthesis of GMP from XMP
AY555_RS06320	COG2089	acid synthase
AY555_RS06335	COG2081	HI0933 family
AY555_RS06360	COG2132	Multicopper oxidase
AY555_RS06375	COG1301	dicarboxylic acid transport
AY555_RS06385	COG0582	viral genome integration into host DNA
AY555_RS06630	COG5328	Belongs to the UPF0262 family
AY555_RS06635	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AY555_RS06640	COG0784	Response regulator, receiver
AY555_RS06640	COG3437	response regulator, receiver
AY555_RS06645	COG4191	Histidine kinase
AY555_RS06645	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AY555_RS06665	COG1530	ribonuclease E activity
AY555_RS06670	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AY555_RS06680	COG1126	abc transporter atp-binding protein
AY555_RS06685	COG0765	amino acid transport
AY555_RS06690	COG4597	amino acid ABC transporter
AY555_RS06695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AY555_RS06700	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AY555_RS06705	COG0248	Ppx GppA phosphatase
AY555_RS06710	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AY555_RS06720	COG0628	permease
AY555_RS06730	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AY555_RS06735	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AY555_RS06740	COG2833	Protein of unknown function (DUF455)
AY555_RS06745	COG0697	spore germination
AY555_RS06755	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AY555_RS06760	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AY555_RS06765	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AY555_RS06775	COG1940	carbohydrate kinase activity
AY555_RS06780	COG0616	signal peptide processing
AY555_RS06785	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AY555_RS06790	COG2095	MarC family integral membrane protein
AY555_RS06795	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AY555_RS06800	COG0142	geranyltranstransferase activity
AY555_RS06805	COG1722	exodeoxyribonuclease VII activity
AY555_RS06815	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AY555_RS06820	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AY555_RS06825	COG0527	aspartate kinase activity
AY555_RS06830	COG2070	2-Nitropropane dioxygenase
AY555_RS06835	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
AY555_RS06845	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AY555_RS06850	COG0124	histidyl-tRNA synthetase
AY555_RS06855	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AY555_RS06865	COG2890	protein-(glutamine-N5) methyltransferase activity
AY555_RS06880	COG0739	heme binding
AY555_RS06935	COG0542	response to heat
AY555_RS06945	COG1611	Belongs to the LOG family
AY555_RS06950	COG1322	Protein conserved in bacteria
AY555_RS06955	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AY555_RS06960	COG3660	Nucleoside-diphosphate-sugar epimerase
AY555_RS06965	COG1028	Short-chain dehydrogenase reductase Sdr
AY555_RS06975	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AY555_RS06980	COG3622	Belongs to the hyi family
AY555_RS06985	COG0187	DNA topoisomerase II activity
AY555_RS06995	COG3474	cytochrome
AY555_RS07020	COG4310	Domain of unknown function (DUF2172)
AY555_RS07035	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AY555_RS07050	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AY555_RS07055	COG0730	response to heat
AY555_RS07060	COG0318	PFAM AMP-dependent synthetase and ligase
AY555_RS07065	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AY555_RS07070	COG0415	Belongs to the DNA photolyase family
AY555_RS07100	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
AY555_RS07105	COG0295	cytidine deaminase activity
AY555_RS07110	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AY555_RS07115	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AY555_RS07120	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AY555_RS07130	COG0564	pseudouridine synthase activity
AY555_RS07135	COG1509	lysine 2,3-aminomutase activity
AY555_RS07150	COG1960	acyl-CoA dehydrogenase activity
AY555_RS07155	COG1024	Enoyl-CoA hydratase
AY555_RS07155	COG1250	3-hydroxyacyl-CoA dehydrogenase
AY555_RS07160	COG0183	Belongs to the thiolase family
AY555_RS07165	COG0318	PFAM AMP-dependent synthetase and ligase
AY555_RS07185	COG1674	ftsk spoiiie
AY555_RS07190	COG0596	Alpha beta hydrolase
AY555_RS07200	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AY555_RS07210	COG2205	protein histidine kinase activity
AY555_RS07210	COG0784	Response regulator, receiver
AY555_RS07215	COG3220	belongs to the UPF0276 family
AY555_RS07225	COG5002	protein histidine kinase activity
AY555_RS07230	COG0745	RESPONSE REGULATOR receiver
AY555_RS07245	COG0835	chemotaxis
AY555_RS07280	COG0174	glutamine synthetase
AY555_RS07285	COG1832	CoA-binding protein
AY555_RS07290	COG3263	regulation of cellular component size
AY555_RS07295	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AY555_RS07300	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AY555_RS07315	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AY555_RS07320	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AY555_RS07330	COG1845	cytochrome c oxidase, subunit III
AY555_RS07335	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AY555_RS07335	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AY555_RS07350	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AY555_RS07355	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AY555_RS07365	COG1703	isobutyryl-CoA mutase activity
AY555_RS07385	COG1309	transcriptional regulator
AY555_RS07390	COG4106	trans-aconitate 2-methyltransferase activity
AY555_RS07405	COG0254	rRNA binding
AY555_RS07425	COG0483	inositol monophosphate 1-phosphatase activity
AY555_RS07430	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AY555_RS07435	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AY555_RS07440	COG0352	thiamine-phosphate diphosphorylase activity
AY555_RS07465	COG1692	metallophosphoesterase
AY555_RS07470	COG0217	transcriptional regulatory protein
AY555_RS07475	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AY555_RS07490	COG0824	Thioesterase
AY555_RS07510	COG0823	Involved in the tonB-independent uptake of proteins
AY555_RS07515	COG2885	chlorophyll binding
AY555_RS07525	COG0037	tRNA processing
AY555_RS07530	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AY555_RS07535	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AY555_RS07545	COG0352	thiamine-phosphate diphosphorylase activity
AY555_RS07545	COG0351	phosphomethylpyrimidine kinase
AY555_RS07560	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AY555_RS07585	COG0719	Fe-S assembly protein
AY555_RS07595	COG0719	Fe-S assembly protein
AY555_RS07600	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AY555_RS07605	COG2151	metal-sulfur cluster biosynthetic enzyme
AY555_RS07610	COG0316	Belongs to the HesB IscA family
AY555_RS07645	COG0488	(ABC) transporter
AY555_RS07650	COG3842	ATPase activity
AY555_RS07655	COG4120	Belongs to the binding-protein-dependent transport system permease family
AY555_RS07675	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AY555_RS07680	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AY555_RS07705	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AY555_RS07725	COG2814	Major facilitator Superfamily
AY555_RS07730	COG0442	prolyl-tRNA aminoacylation
AY555_RS07740	COG1136	(ABC) transporter
AY555_RS07750	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AY555_RS07770	COG0528	UMP kinase activity
AY555_RS07780	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AY555_RS07790	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AY555_RS07795	COG0750	zinc metalloprotease
AY555_RS07810	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AY555_RS07825	COG3494	Protein of unknown function (DUF1009)
AY555_RS07840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AY555_RS07845	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AY555_RS07855	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AY555_RS07860	COG0242	peptide deformylase activity
AY555_RS07875	COG0583	DNA-binding transcription factor activity
AY555_RS07880	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AY555_RS07930	COG0494	nUDIX hydrolase
AY555_RS07940	COG0564	pseudouridine synthase activity
AY555_RS07950	COG0513	Belongs to the DEAD box helicase family
AY555_RS07985	COG2885	chlorophyll binding
AY555_RS07985	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AY555_RS07990	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AY555_RS07995	COG0736	holo-[acyl-carrier-protein] synthase activity
AY555_RS08000	COG0681	Belongs to the peptidase S26 family
AY555_RS08005	COG0571	ribonuclease III activity
AY555_RS08010	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AY555_RS08015	COG1381	Involved in DNA repair and RecF pathway recombination
AY555_RS08020	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AY555_RS08030	COG1360	Flagellar Motor Protein
AY555_RS08035	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AY555_RS08040	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AY555_RS08050	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AY555_RS08050	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AY555_RS08065	COG0544	peptidyl-prolyl cis-trans isomerase activity
AY555_RS08075	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AY555_RS08080	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AY555_RS08085	COG0508	dehydrogenase complex catalyzes the overall conversion of
AY555_RS08085	COG0022	dehydrogenase e1 component
AY555_RS08090	COG0508	dehydrogenase complex catalyzes the overall conversion of
AY555_RS08095	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AY555_RS08100	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AY555_RS08105	COG2867	negative regulation of translational initiation
AY555_RS08115	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AY555_RS08120	COG0739	heme binding
AY555_RS08130	COG0113	porphobilinogen synthase activity
AY555_RS08135	COG1024	Enoyl-CoA hydratase
AY555_RS08155	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AY555_RS08160	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AY555_RS08165	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AY555_RS08165	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AY555_RS08175	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AY555_RS08175	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AY555_RS08185	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AY555_RS08190	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AY555_RS08200	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AY555_RS08220	COG0416	fatty acid biosynthetic process
AY555_RS08245	COG1234	tRNA 3'-trailer cleavage
AY555_RS08255	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AY555_RS08265	COG2890	protein-(glutamine-N5) methyltransferase activity
AY555_RS08295	COG2204	response regulator
AY555_RS08300	COG0569	domain protein
AY555_RS08305	COG0546	phosphoglycolate phosphatase activity
AY555_RS08310	COG1923	regulation of RNA biosynthetic process
AY555_RS08315	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AY555_RS08320	COG0483	inositol monophosphate 1-phosphatase activity
AY555_RS08340	COG1862	Preprotein translocase
AY555_RS08350	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AY555_RS08350	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AY555_RS08355	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AY555_RS08355	COG0045	succinate-CoA ligase (ADP-forming) activity
AY555_RS08355	COG1042	CoA-binding domain protein
AY555_RS08370	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AY555_RS08375	COG1538	Outer membrane efflux protein
AY555_RS08385	COG0525	valine-tRNA ligase activity
AY555_RS08410	COG2755	lipolytic protein G-D-S-L family
AY555_RS08410	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AY555_RS08445	COG2951	lytic endotransglycosylase activity
AY555_RS08455	COG1686	Belongs to the peptidase S11 family
AY555_RS08460	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AY555_RS08470	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AY555_RS08475	COG0084	hydrolase, TatD family'
AY555_RS08490	COG1233	COG1233 Phytoene dehydrogenase and related
AY555_RS08495	COG1562	ergosterol biosynthetic process
AY555_RS08515	COG0316	Belongs to the HesB IscA family
AY555_RS08520	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AY555_RS08525	COG0018	arginyl-trna synthetase
AY555_RS08535	COG1472	Belongs to the glycosyl hydrolase 3 family
AY555_RS08540	COG1994	Peptidase M50
AY555_RS08555	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AY555_RS08565	COG3956	TIGRFAM MazG family protein
AY555_RS08580	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AY555_RS08585	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AY555_RS08590	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AY555_RS08600	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AY555_RS08610	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AY555_RS08625	COG0805	protein transport
AY555_RS08630	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AY555_RS08635	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AY555_RS08640	COG3842	ATPase activity
AY555_RS08655	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AY555_RS08660	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AY555_RS08680	COG0346	lactoylglutathione lyase activity
AY555_RS08700	COG1007	ATP synthesis coupled electron transport
AY555_RS08725	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AY555_RS08730	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AY555_RS08735	COG1034	ATP synthesis coupled electron transport
AY555_RS08745	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AY555_RS08755	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AY555_RS08760	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AY555_RS08770	COG2867	negative regulation of translational initiation
AY555_RS08795	COG0626	cystathionine gamma-synthase activity
AY555_RS08800	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AY555_RS08805	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AY555_RS08810	COG0741	lytic transglycosylase activity
AY555_RS08830	COG1758	RNA polymerase activity
AY555_RS08835	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AY555_RS08845	COG1573	uracil-dna glycosylase
AY555_RS08865	COG0148	phosphopyruvate hydratase activity
AY555_RS08870	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AY555_RS08875	COG0504	CTP synthase activity
AY555_RS08880	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AY555_RS08885	COG0149	triose-phosphate isomerase activity
AY555_RS08895	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AY555_RS08900	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AY555_RS08905	COG2608	mercury ion transmembrane transporter activity
AY555_RS08910	COG2861	carbohydrate metabolic process
AY555_RS08915	COG2217	Heavy metal translocating P-type atpase
AY555_RS08925	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AY555_RS08935	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AY555_RS08940	COG0658	competence protein
AY555_RS08940	COG2333	competence protein COMEC
AY555_RS08945	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AY555_RS08950	COG0372	Belongs to the citrate synthase family
AY555_RS08960	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AY555_RS08975	COG4149	molybdate abc transporter
AY555_RS08980	COG1840	ABC-type Fe3 transport system, periplasmic component
AY555_RS08985	COG0215	cysteine-tRNA ligase activity
AY555_RS08995	COG0280	phosphate acetyltransferase
AY555_RS08995	COG0281	malic enzyme
AY555_RS09000	COG4770	biotin carboxylase activity
AY555_RS09005	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AY555_RS09010	COG1028	Short-chain dehydrogenase reductase Sdr
AY555_RS09045	COG3750	Belongs to the UPF0335 family
AY555_RS09055	COG0469	pyruvate kinase activity
AY555_RS09070	COG0513	Belongs to the DEAD box helicase family
AY555_RS09075	COG0400	carboxylic ester hydrolase activity
AY555_RS09090	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AY555_RS09115	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AY555_RS09125	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AY555_RS09130	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AY555_RS09150	COG0252	asparaginase activity
AY555_RS09155	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AY555_RS09155	COG0758	DNA mediated transformation
AY555_RS09160	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AY555_RS09165	COG0557	exoribonuclease II activity
AY555_RS09170	COG0793	Belongs to the peptidase S41A family
AY555_RS09175	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AY555_RS09185	COG2363	Small membrane protein
AY555_RS09200	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AY555_RS09215	COG1749	Flagellar hook protein flgE
AY555_RS09230	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AY555_RS09235	COG0511	ligase activity, forming carbon-carbon bonds
AY555_RS09240	COG0439	Biotin carboxylase
AY555_RS09270	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AY555_RS09290	COG0156	8-amino-7-oxononanoate synthase activity
AY555_RS09300	COG0191	fructose-bisphosphate aldolase activity
AY555_RS09340	COG1749	Flagellar hook protein flgE
AY555_RS09345	COG1766	The M ring may be actively involved in energy transduction
AY555_RS09350	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AY555_RS09360	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AY555_RS09365	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AY555_RS09370	COG2204	response regulator
AY555_RS09375	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AY555_RS09380	COG0552	protein localization to endoplasmic reticulum
AY555_RS09395	COG0484	heat shock protein binding
AY555_RS09405	COG0848	biopolymer transport protein
AY555_RS09435	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AY555_RS09450	COG2009	succinate dehydrogenase
AY555_RS09460	COG1053	succinate dehydrogenase
AY555_RS09465	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AY555_RS09470	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AY555_RS09470	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AY555_RS09475	COG1494	fructose-1,6-bisphosphatase
AY555_RS09485	COG0436	Aminotransferase
AY555_RS09495	COG3243	poly(R)-hydroxyalkanoic acid synthase
AY555_RS09500	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AY555_RS09505	COG1028	Short-chain dehydrogenase reductase Sdr
AY555_RS09520	COG1396	sequence-specific DNA binding
AY555_RS09535	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AY555_RS09545	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AY555_RS09550	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AY555_RS09555	COG0047	phosphoribosylformylglycinamidine synthase activity
AY555_RS09560	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AY555_RS09585	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AY555_RS09590	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AY555_RS09595	COG2201	protein-glutamate methylesterase activity
AY555_RS09600	COG0745	RESPONSE REGULATOR receiver
AY555_RS09605	COG2198	Histidine kinase
AY555_RS09605	COG0784	Response regulator, receiver
AY555_RS09605	COG0643	Histidine kinase
AY555_RS09615	COG1643	Atp-dependent helicase
AY555_RS09620	COG0156	8-amino-7-oxononanoate synthase activity
AY555_RS09630	COG4106	trans-aconitate 2-methyltransferase activity
AY555_RS09635	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AY555_RS09635	COG4106	trans-aconitate 2-methyltransferase activity
AY555_RS09640	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AY555_RS09650	COG2183	response to ionizing radiation
AY555_RS09675	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AY555_RS09680	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AY555_RS09690	COG0438	transferase activity, transferring glycosyl groups
AY555_RS09695	COG0463	Glycosyl transferase, family 2
AY555_RS09710	COG0354	folic acid binding
AY555_RS09720	COG0574	Belongs to the PEP-utilizing enzyme family
AY555_RS09720	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AY555_RS09730	COG0752	glycyl-tRNA synthetase alpha subunit
AY555_RS09740	COG0142	geranyltranstransferase activity
AY555_RS09760	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AY555_RS09765	COG2116	formate transmembrane transporter activity
AY555_RS09780	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AY555_RS09805	COG1126	abc transporter atp-binding protein
AY555_RS09810	COG0765	amino acid transport
AY555_RS09815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AY555_RS09820	COG1438	arginine binding
AY555_RS09830	COG0297	glycogen (starch) synthase activity
AY555_RS09855	COG0489	protein tyrosine kinase activity
AY555_RS09855	COG3206	protein involved in exopolysaccharide biosynthesis
AY555_RS09880	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AY555_RS09885	COG1187	pseudouridine synthase activity
AY555_RS09890	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AY555_RS09905	COG0463	Glycosyl transferase, family 2
AY555_RS09915	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AY555_RS09945	COG0837	glucose binding
AY555_RS10520	COG0814	amino acid
AY555_RS10720	COG2003	Belongs to the UPF0758 family
AY555_RS10795	COG1960	acyl-CoA dehydrogenase activity
AY555_RS10800	COG1960	acyl-CoA dehydrogenase activity
AY555_RS10855	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AY555_RS11400	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate