locus-tag	class	description
BV083_RS00005	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BV083_RS00010	COG1022	Amp-dependent synthetase and ligase
BV083_RS00015	COG0561	phosphatase activity
BV083_RS00020	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BV083_RS00040	COG0437	4 iron, 4 sulfur cluster binding
BV083_RS00045	COG2864	formate dehydrogenase
BV083_RS00055	COG0456	acetyltransferase
BV083_RS00060	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
BV083_RS00080	COG0681	Belongs to the peptidase S26 family
BV083_RS00105	COG0471	metal ion transport
BV083_RS00110	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
BV083_RS00110	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
BV083_RS00115	COG3051	citrate lyase alpha subunit
BV083_RS00120	COG2301	Belongs to the HpcH HpaI aldolase family
BV083_RS00130	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
BV083_RS00135	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BV083_RS00150	COG1686	Belongs to the peptidase S11 family
BV083_RS00155	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BV083_RS00155	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BV083_RS00160	COG0772	Belongs to the SEDS family
BV083_RS00165	COG0768	penicillin binding
BV083_RS00175	COG0799	negative regulation of ribosome biogenesis
BV083_RS00185	COG4178	(ABC) transporter
BV083_RS00190	COG1077	Cell shape determining protein MreB Mrl
BV083_RS00195	COG1792	Involved in formation and maintenance of cell shape
BV083_RS00200	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BV083_RS00205	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
BV083_RS00210	COG0708	Exodeoxyribonuclease III
BV083_RS00215	COG0564	pseudouridine synthase activity
BV083_RS00220	COG3768	UPF0283 membrane protein
BV083_RS00225	COG0670	Belongs to the BI1 family
BV083_RS00235	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
BV083_RS00240	COG2824	Alkylphosphonate utilization operon protein PhnA
BV083_RS00245	COG0800	Aldolase
BV083_RS00250	COG1028	Short-chain dehydrogenase reductase Sdr
BV083_RS00255	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BV083_RS00260	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BV083_RS00265	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BV083_RS00270	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BV083_RS00275	COG1063	alcohol dehydrogenase
BV083_RS00280	COG2186	Transcriptional regulator
BV083_RS00290	COG0861	Integral membrane protein TerC family
BV083_RS00315	COG2333	competence protein COMEC
BV083_RS00315	COG0658	competence protein
BV083_RS00320	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BV083_RS00325	COG0617	tRNA 3'-terminal CCA addition
BV083_RS00330	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BV083_RS00335	COG0802	atpase or kinase
BV083_RS00340	COG1388	LysM domain
BV083_RS00340	COG0860	N-Acetylmuramoyl-L-alanine amidase
BV083_RS00355	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BV083_RS00360	COG0497	DNA recombination
BV083_RS00370	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BV083_RS00375	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
BV083_RS00380	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
BV083_RS00385	COG1328	CTP reductase activity
BV083_RS00385	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BV083_RS00390	COG1946	Acyl-CoA thioesterase
BV083_RS00400	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BV083_RS00405	COG0084	hydrolase, TatD family'
BV083_RS00415	COG3118	belongs to the thioredoxin family
BV083_RS00420	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BV083_RS00425	COG0626	cystathionine gamma-synthase activity
BV083_RS00485	COG0629	single-stranded DNA binding
BV083_RS00700	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BV083_RS00710	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BV083_RS00720	COG0460	homoserine dehydrogenase
BV083_RS00720	COG0527	aspartate kinase activity
BV083_RS00725	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BV083_RS00730	COG4797	methyltransferase
BV083_RS00730	COG4797	methyltransferase
BV083_RS00735	COG1840	ABC-type Fe3 transport system, periplasmic component
BV083_RS00740	COG1178	ABC-type Fe3 transport system permease component
BV083_RS00750	COG1876	peptidase activity
BV083_RS00760	COG1393	Belongs to the ArsC family
BV083_RS00770	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BV083_RS00775	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BV083_RS00795	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BV083_RS00800	COG4536	flavin adenine dinucleotide binding
BV083_RS00805	COG3610	response to peptide
BV083_RS00810	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
BV083_RS00820	COG0625	glutathione transferase activity
BV083_RS00880	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BV083_RS00885	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BV083_RS00890	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
BV083_RS00895	COG5413	integral membrane protein
BV083_RS00900	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BV083_RS00905	COG0626	cystathionine gamma-synthase activity
BV083_RS00910	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BV083_RS00930	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BV083_RS00935	COG2252	PERMEase
BV083_RS00960	COG1160	GTP binding
BV083_RS00975	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BV083_RS00990	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BV083_RS01000	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BV083_RS01005	COG1737	Transcriptional regulator
BV083_RS01015	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
BV083_RS01025	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BV083_RS01025	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BV083_RS01035	COG2020	methyltransferase activity
BV083_RS01040	COG0330	HflC and HflK could
BV083_RS01045	COG0330	HflC and HflK could
BV083_RS01050	COG2091	lysine biosynthetic process via aminoadipic acid
BV083_RS01055	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BV083_RS01065	COG1028	Short-chain dehydrogenase reductase Sdr
BV083_RS01070	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BV083_RS01090	COG1399	metal-binding, possibly nucleic acid-binding protein
BV083_RS01095	COG0688	phosphatidylethanolamine metabolic process
BV083_RS01100	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BV083_RS01105	COG3056	Lipoprotein
BV083_RS01110	COG0271	Belongs to the BolA IbaG family
BV083_RS01115	COG1115	amino acid carrier protein
BV083_RS01125	COG2116	formate transmembrane transporter activity
BV083_RS01130	COG1882	Formate acetyltransferase
BV083_RS01135	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BV083_RS01145	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BV083_RS01150	COG0564	pseudouridine synthase activity
BV083_RS01155	COG1496	oxidoreductase activity
BV083_RS01165	COG2991	Protein conserved in bacteria
BV083_RS01170	COG1477	protein flavinylation
BV083_RS01190	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BV083_RS01210	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BV083_RS01215	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BV083_RS01220	COG0789	Transcriptional regulator
BV083_RS01235	COG0805	protein transport
BV083_RS01240	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BV083_RS01245	COG0735	belongs to the Fur family
BV083_RS01250	COG0716	FMN binding
BV083_RS01255	COG0596	Alpha beta hydrolase
BV083_RS01260	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
BV083_RS01265	COG0318	PFAM AMP-dependent synthetase and ligase
BV083_RS01270	COG3264	Mechanosensitive ion channel
BV083_RS01270	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
BV083_RS01280	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
BV083_RS01285	COG0730	response to heat
BV083_RS01290	COG1560	Kdo2-lipid A biosynthetic process
BV083_RS01325	COG0737	Belongs to the 5'-nucleotidase family
BV083_RS01340	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BV083_RS01345	COG0671	phosphoesterase, PA-phosphatase related
BV083_RS01355	COG4166	transmembrane transport
BV083_RS01360	COG2832	Protein of unknown function (DUF454)
BV083_RS01365	COG0339	signal peptide processing
BV083_RS01375	COG0732	type I restriction modification DNA specificity domain
BV083_RS01395	COG3059	membrane
BV083_RS01405	COG1573	uracil-dna glycosylase
BV083_RS01430	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BV083_RS01445	COG1464	Belongs to the NlpA lipoprotein family
BV083_RS01450	COG1349	DNA-binding transcription factor activity
BV083_RS01455	COG0705	Rhomboid family
BV083_RS01460	COG0564	pseudouridine synthase activity
BV083_RS01470	COG1349	DNA-binding transcription factor activity
BV083_RS01480	COG1070	Carbohydrate kinase
BV083_RS01490	COG0235	Class ii aldolase
BV083_RS01495	COG0738	Major facilitator superfamily
BV083_RS01515	COG0471	metal ion transport
BV083_RS01520	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BV083_RS01525	COG1045	serine acetyltransferase
BV083_RS01535	COG3072	Adenylate cyclase
BV083_RS01540	COG2959	enzyme of heme biosynthesis
BV083_RS01545	COG3071	HemY protein
BV083_RS01590	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BV083_RS01590	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BV083_RS01595	COG0516	GMP reductase activity
BV083_RS01595	COG0517	IMP dehydrogenase activity
BV083_RS01605	COG2962	Rard protein
BV083_RS01610	COG1522	sequence-specific DNA binding
BV083_RS01620	COG1114	Component of the transport system for branched-chain amino acids
BV083_RS01625	COG2731	YhcH YjgK YiaL family protein
BV083_RS01640	COG4785	May be involved in cell division
BV083_RS01645	COG0513	Belongs to the DEAD box helicase family
BV083_RS01660	COG3036	rescue of stalled ribosome
BV083_RS01665	COG1393	Belongs to the ArsC family
BV083_RS01675	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BV083_RS01680	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BV083_RS01685	COG1862	Preprotein translocase
BV083_RS01690	COG0425	Belongs to the sulfur carrier protein TusA family
BV083_RS01695	COG3945	hemerythrin HHE cation binding domain
BV083_RS01710	COG0641	radical SAM
BV083_RS01720	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BV083_RS01725	COG0629	single-stranded DNA binding
BV083_RS01730	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
BV083_RS01735	COG0848	biopolymer transport protein
BV083_RS01740	COG0811	peptide transport
BV083_RS01745	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BV083_RS01755	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BV083_RS01760	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BV083_RS01770	COG1442	glycosyl transferase family 8
BV083_RS01775	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BV083_RS01785	COG0859	PFAM glycosyl transferase family 9
BV083_RS01805	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BV083_RS01815	COG3850	Histidine kinase
BV083_RS01830	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BV083_RS01835	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BV083_RS01840	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BV083_RS01885	COG1368	sulfuric ester hydrolase activity
BV083_RS01900	COG2258	MOSC domain
BV083_RS01905	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
BV083_RS01910	COG0477	Major facilitator Superfamily
BV083_RS01915	COG2267	carboxylic ester hydrolase activity
BV083_RS01925	COG1169	isochorismate synthase
BV083_RS01935	COG0436	Aminotransferase
BV083_RS01940	COG0814	amino acid
BV083_RS01945	COG1760	l-serine dehydratase
BV083_RS01950	COG0814	amino acid
BV083_RS01955	COG2217	Heavy metal translocating P-type atpase
BV083_RS01960	COG2608	mercury ion transmembrane transporter activity
BV083_RS01965	COG2608	mercury ion transmembrane transporter activity
BV083_RS01970	COG2608	mercury ion transmembrane transporter activity
BV083_RS01975	COG2608	mercury ion transmembrane transporter activity
BV083_RS01980	COG0789	Transcriptional regulator
BV083_RS01990	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BV083_RS01995	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BV083_RS02000	COG1459	type II secretion system
BV083_RS02005	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BV083_RS02010	COG4969	Belongs to the N-Me-Phe pilin family
BV083_RS02015	COG3023	N-Acetylmuramoyl-L-alanine amidase
BV083_RS02020	COG4535	Mg2 and Co2 transporter CorC
BV083_RS02025	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BV083_RS02030	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BV083_RS02050	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BV083_RS02055	COG2814	Major facilitator Superfamily
BV083_RS02060	COG4974	Belongs to the 'phage' integrase family
BV083_RS02090	COG0494	nUDIX hydrolase
BV083_RS02100	COG1755	Isoprenylcysteine carboxyl methyltransferase
BV083_RS02120	COG0346	lactoylglutathione lyase activity
BV083_RS02130	COG2056	Na+-H+ antiporter family
BV083_RS02150	COG1509	lysine 2,3-aminomutase activity
BV083_RS02155	COG3061	Opacity-associated protein A
BV083_RS02155	COG3266	domain, Protein
BV083_RS02165	COG1381	Involved in DNA repair and RecF pathway recombination
BV083_RS02195	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BV083_RS02200	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BV083_RS02205	COG0521	Mo-molybdopterin cofactor biosynthetic process
BV083_RS02210	COG0347	Belongs to the P(II) protein family
BV083_RS02215	COG0628	permease
BV083_RS02220	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BV083_RS02230	COG3171	Protein conserved in bacteria
BV083_RS02235	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BV083_RS02240	COG3062	negative regulation of establishment of protein localization
BV083_RS02250	COG0437	4 iron, 4 sulfur cluster binding
BV083_RS02255	COG0348	domain, Protein
BV083_RS02260	COG3043	anaerobic respiration
BV083_RS02265	COG3005	denitrification pathway
BV083_RS02275	COG2814	Major facilitator Superfamily
BV083_RS02280	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BV083_RS02290	COG1116	anion transmembrane transporter activity
BV083_RS02295	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BV083_RS02300	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BV083_RS02305	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BV083_RS02310	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BV083_RS02315	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BV083_RS02320	COG1121	(ABC) transporter
BV083_RS02330	COG1686	Belongs to the peptidase S11 family
BV083_RS02335	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BV083_RS02340	COG3063	Type IV pilus biogenesis stability protein PilW
BV083_RS02345	COG1426	Protein conserved in bacteria
BV083_RS02350	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BV083_RS02360	COG2976	Protein conserved in bacteria
BV083_RS02365	COG2975	iron-sulfur cluster assembly
BV083_RS02370	COG0633	Ferredoxin
BV083_RS02375	COG0443	Heat shock 70 kDa protein
BV083_RS02385	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BV083_RS02390	COG0316	Belongs to the HesB IscA family
BV083_RS02395	COG0822	iron-sulfur transferase activity
BV083_RS02405	COG1959	2 iron, 2 sulfur cluster binding
BV083_RS02410	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
BV083_RS02425	COG2885	chlorophyll binding
BV083_RS02435	COG3064	Membrane
BV083_RS02440	COG0848	biopolymer transport protein
BV083_RS02445	COG0811	peptide transport
BV083_RS02450	COG0824	Thioesterase
BV083_RS02455	COG1199	ATP-dependent helicase activity
BV083_RS02460	COG1214	PFAM Peptidase M22, glycoprotease
BV083_RS02465	COG3065	identical protein binding
BV083_RS02470	COG0318	PFAM AMP-dependent synthetase and ligase
BV083_RS02475	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BV083_RS02480	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BV083_RS02485	COG0012	GTP binding
BV083_RS02490	COG0193	aminoacyl-tRNA hydrolase activity
BV083_RS02500	COG2850	peptidyl-arginine hydroxylation
BV083_RS02510	COG0494	nUDIX hydrolase
BV083_RS02515	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BV083_RS02520	COG3691	Protein conserved in bacteria
BV083_RS02525	COG2067	long-chain fatty acid transport protein
BV083_RS02530	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BV083_RS02540	COG0037	tRNA processing
BV083_RS02550	COG0825	malonyl-CoA metabolic process
BV083_RS02555	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BV083_RS02560	COG1121	(ABC) transporter
BV083_RS02565	COG0739	heme binding
BV083_RS02570	COG3283	Transcriptional regulator of aromatic amino acids metabolism
BV083_RS02580	COG0564	pseudouridine synthase activity
BV083_RS02585	COG1530	ribonuclease E activity
BV083_RS02590	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BV083_RS02600	COG0351	phosphomethylpyrimidine kinase
BV083_RS02610	COG0477	Major facilitator Superfamily
BV083_RS02615	COG0826	peptidase U32
BV083_RS02620	COG0513	Belongs to the DEAD box helicase family
BV083_RS02630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BV083_RS02635	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BV083_RS02655	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BV083_RS02660	COG0776	regulation of translation
BV083_RS02665	COG3068	Protein conserved in bacteria
BV083_RS02680	COG1040	competence protein
BV083_RS02685	COG4796	Type ii and iii secretion system protein
BV083_RS02700	COG3166	PFAM Fimbrial assembly family protein
BV083_RS02705	COG4972	Pilus assembly protein
BV083_RS02710	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BV083_RS02715	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BV083_RS02720	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BV083_RS02730	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BV083_RS02735	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BV083_RS02745	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BV083_RS02745	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
BV083_RS02745	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BV083_RS02750	COG1105	Belongs to the carbohydrate kinase PfkB family
BV083_RS02755	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BV083_RS02755	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BV083_RS02765	COG3309	Virulence-associated protein D
BV083_RS02775	COG1253	flavin adenine dinucleotide binding
BV083_RS02785	COG0084	hydrolase, TatD family'
BV083_RS02790	COG0470	DNA polymerase III
BV083_RS02800	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BV083_RS02805	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BV083_RS02815	COG3956	TIGRFAM MazG family protein
BV083_RS02820	COG2990	Protein conserved in bacteria
BV083_RS02825	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BV083_RS02830	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BV083_RS02835	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BV083_RS02840	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BV083_RS02845	COG0354	folic acid binding
BV083_RS02850	COG1561	YicC-like family, N-terminal region
BV083_RS02860	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BV083_RS02865	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BV083_RS02890	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BV083_RS02890	COG0140	phosphoribosyl-ATP diphosphatase activity
BV083_RS02895	COG0814	amino acid
BV083_RS02940	COG3312	ion transport
BV083_RS02955	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BV083_RS02960	COG1238	metal cluster binding
BV083_RS02975	COG3700	Belongs to the class B bacterial acid phosphatase family
BV083_RS02990	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BV083_RS02995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BV083_RS03000	COG1322	Protein conserved in bacteria
BV083_RS03010	COG1129	ABC transporter
BV083_RS03015	COG1172	Belongs to the binding-protein-dependent transport system permease family
BV083_RS03020	COG1879	ABC-type sugar transport system periplasmic component
BV083_RS03025	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BV083_RS03030	COG1609	Transcriptional regulator
BV083_RS03045	COG1575	Belongs to the MenA family. Type 1 subfamily
BV083_RS03050	COG1720	tRNA m6t6A37 methyltransferase activity
BV083_RS03055	COG1275	C4-dicarboxylate transporter malic acid transport protein
BV083_RS03090	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BV083_RS03095	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BV083_RS03100	COG1328	CTP reductase activity
BV083_RS03105	COG2364	Membrane
BV083_RS03110	COG0859	PFAM glycosyl transferase family 9
BV083_RS03115	COG0191	fructose-bisphosphate aldolase activity
BV083_RS03125	COG3719	Belongs to the RNase T2 family
BV083_RS03130	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BV083_RS03135	COG0814	amino acid
BV083_RS03140	COG1435	thymidine kinase activity
BV083_RS03145	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BV083_RS03155	COG0358	DNA primase activity
BV083_RS03160	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BV083_RS03165	COG1027	Aspartate ammonia-lyase
BV083_RS03175	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BV083_RS03190	COG0804	urea catabolic process
BV083_RS03205	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BV083_RS03270	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BV083_RS03285	COG0363	glucosamine-6-phosphate deaminase activity
BV083_RS03290	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BV083_RS03295	COG1218	3'(2'),5'-bisphosphate nucleotidase
BV083_RS03305	COG1297	OPT oligopeptide transporter protein
BV083_RS03315	COG1522	sequence-specific DNA binding
BV083_RS03325	COG2801	Transposase and inactivated derivatives
BV083_RS03340	COG2801	Transposase and inactivated derivatives
BV083_RS03355	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BV083_RS03360	COG0187	DNA topoisomerase II activity
BV083_RS03365	COG2183	response to ionizing radiation
BV083_RS03370	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BV083_RS03375	COG1309	transcriptional regulator
BV083_RS03380	COG0583	DNA-binding transcription factor activity
BV083_RS03385	COG0678	peroxiredoxin activity
BV083_RS03385	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BV083_RS03395	COG0545	Peptidyl-prolyl cis-trans isomerase
BV083_RS03400	COG2964	Protein conserved in bacteria
BV083_RS03405	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
BV083_RS03410	COG2923	Belongs to the DsrF TusC family
BV083_RS03415	COG2168	tRNA wobble position uridine thiolation
BV083_RS03435	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BV083_RS03450	COG0789	Transcriptional regulator
BV083_RS03455	COG0737	Belongs to the 5'-nucleotidase family
BV083_RS03460	COG1473	amidohydrolase
BV083_RS03465	COG3069	C4-dicarboxylate transmembrane transporter activity
BV083_RS03485	COG1288	antiporter activity
BV083_RS03490	COG0549	Belongs to the carbamate kinase family
BV083_RS03495	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BV083_RS03500	COG0561	phosphatase activity
BV083_RS03520	COG3070	regulator of competence-specific genes
BV083_RS03555	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BV083_RS03555	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BV083_RS03560	COG0569	domain protein
BV083_RS03565	COG1970	mechanosensitive ion channel activity
BV083_RS03575	COG1595	DNA-templated transcription, initiation
BV083_RS03580	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
BV083_RS03585	COG3026	antisigma factor binding
BV083_RS03590	COG1072	(Pantothenic acid kinase))
BV083_RS03625	COG0038	chloride channel
BV083_RS03630	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BV083_RS03635	COG3691	Protein conserved in bacteria
BV083_RS03640	COG0180	Tryptophanyl-tRNA synthetase
BV083_RS03650	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BV083_RS03695	COG3005	denitrification pathway
BV083_RS03700	COG2267	carboxylic ester hydrolase activity
BV083_RS03705	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BV083_RS03710	COG1285	pathogenesis
BV083_RS03715	COG2249	NAD(P)H dehydrogenase (quinone) activity
BV083_RS03720	COG0583	DNA-binding transcription factor activity
BV083_RS03725	COG0210	DNA helicase
BV083_RS03730	COG5645	(Lipo)protein
BV083_RS03740	COG1519	Transferase
BV083_RS03745	COG0463	Glycosyl transferase, family 2
BV083_RS03750	COG2818	Glycosylase
BV083_RS03770	COG0551	DNA topoisomerase type I activity
BV083_RS03775	COG0488	(ABC) transporter
BV083_RS03780	COG3620	sequence-specific DNA binding
BV083_RS03785	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
BV083_RS03800	COG4988	ABC transporter
BV083_RS03805	COG1132	(ABC) transporter
BV083_RS03810	COG3550	peptidyl-serine autophosphorylation
BV083_RS03815	COG3550	peptidyl-serine autophosphorylation
BV083_RS03825	COG1494	fructose-1,6-bisphosphatase
BV083_RS03835	COG0716	FMN binding
BV083_RS03865	COG2801	Transposase and inactivated derivatives
BV083_RS03870	COG2801	Transposase and inactivated derivatives
BV083_RS03885	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BV083_RS03890	COG1120	ATPase activity
BV083_RS03895	COG0247	lactate metabolic process
BV083_RS03905	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BV083_RS03910	COG2271	Major facilitator Superfamily
BV083_RS03925	COG0584	glycerophosphoryl diester phosphodiesterase
BV083_RS03930	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BV083_RS03935	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BV083_RS03940	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
BV083_RS03945	COG2195	Cleaves the N-terminal amino acid of tripeptides
BV083_RS03955	COG0456	acetyltransferase
BV083_RS03970	COG2962	Rard protein
BV083_RS03975	COG0583	DNA-binding transcription factor activity
BV083_RS03985	COG0584	glycerophosphoryl diester phosphodiesterase
BV083_RS03990	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BV083_RS03995	COG1187	pseudouridine synthase activity
BV083_RS04000	COG0248	Ppx GppA phosphatase
BV083_RS04005	COG2911	Protein conserved in bacteria
BV083_RS04010	COG0729	surface antigen
BV083_RS04015	COG1047	Peptidyl-prolyl cis-trans
BV083_RS04020	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
BV083_RS04030	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BV083_RS04035	COG1238	metal cluster binding
BV083_RS04045	COG1388	LysM domain
BV083_RS04045	COG4942	peptidase
BV083_RS04065	COG1921	L-seryl-tRNASec selenium transferase activity
BV083_RS04070	COG3276	selenocysteine insertion sequence binding
BV083_RS04080	COG3077	Addiction module antitoxin, RelB DinJ family
BV083_RS04085	COG3041	Addiction module toxin RelE StbE family
BV083_RS04105	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BV083_RS04110	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BV083_RS04115	COG0250	Participates in transcription elongation, termination and antitermination
BV083_RS04120	COG2853	Lipoprotein
BV083_RS04125	COG0251	oxidation-reduction process
BV083_RS04140	COG1739	Uncharacterized protein family UPF0029
BV083_RS04145	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BV083_RS04185	COG2197	response regulator
BV083_RS04190	COG0019	diaminopimelate decarboxylase activity
BV083_RS04205	COG0514	ATP-dependent DNA helicase (RecQ)
BV083_RS04225	COG0204	Acyl-transferase
BV083_RS04230	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BV083_RS04240	COG0733	neurotransmitter:sodium symporter activity
BV083_RS04250	COG0028	Belongs to the TPP enzyme family
BV083_RS04260	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BV083_RS04265	COG0587	DNA-directed DNA polymerase activity
BV083_RS04270	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BV083_RS04280	COG0702	epimerase
BV083_RS04290	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BV083_RS04295	COG0252	asparaginase activity
BV083_RS04300	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BV083_RS04305	COG1252	NADH dehydrogenase
BV083_RS04310	COG2937	Belongs to the GPAT DAPAT family
BV083_RS04320	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BV083_RS04325	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BV083_RS04350	COG2861	carbohydrate metabolic process
BV083_RS04355	COG4942	peptidase
BV083_RS04370	COG1194	a g-specific adenine glycosylase
BV083_RS04395	COG2129	metallophosphoesterase
BV083_RS04400	COG3172	ATPase kinase involved in NAD metabolism
BV083_RS04410	COG3306	glycosyltransferase involved in LPS biosynthesis
BV083_RS04415	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BV083_RS04420	COG0742	ribosomal rna small subunit methyltransferase
BV083_RS04425	COG0552	protein localization to endoplasmic reticulum
BV083_RS04430	COG2884	Cell division ATP-binding protein ftsE
BV083_RS04435	COG2177	Part of the ABC transporter FtsEX involved in
BV083_RS04475	COG2390	Transcriptional regulator
BV083_RS04480	COG1070	Carbohydrate kinase
BV083_RS04485	COG0051	transcription antitermination factor activity, RNA binding
BV083_RS04490	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BV083_RS04510	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BV083_RS04595	COG0201	protein transport
BV083_RS04635	COG0641	radical SAM
BV083_RS04640	COG0730	response to heat
BV083_RS04670	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BV083_RS04685	COG0589	response to stress
BV083_RS04690	COG0006	proline dipeptidase activity
BV083_RS04700	COG2017	converts alpha-aldose to the beta-anomer
BV083_RS04710	COG1085	galactose-1-phosphate uridylyltransferase
BV083_RS04715	COG1609	Transcriptional regulator
BV083_RS04720	COG1879	ABC-type sugar transport system periplasmic component
BV083_RS04725	COG1129	ABC transporter
BV083_RS04730	COG4211	Belongs to the binding-protein-dependent transport system permease family
BV083_RS04745	COG1607	acyl-coa hydrolase
BV083_RS04750	COG2350	Protein conserved in bacteria
BV083_RS04755	COG0741	lytic transglycosylase activity
BV083_RS04765	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BV083_RS04775	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
BV083_RS04780	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BV083_RS04785	COG1053	succinate dehydrogenase
BV083_RS04800	COG0745	RESPONSE REGULATOR receiver
BV083_RS04805	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BV083_RS04820	COG3083	sulfuric ester hydrolase activity
BV083_RS04825	COG0402	S-adenosylhomocysteine deaminase activity
BV083_RS04830	COG0746	molybdenum cofactor guanylyltransferase activity
BV083_RS04835	COG3084	Protein conserved in bacteria
BV083_RS04840	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BV083_RS04845	COG3085	chromosome segregation
BV083_RS04860	COG3086	response to oxidative stress
BV083_RS04870	COG1763	Mo-molybdopterin cofactor biosynthetic process
BV083_RS04875	COG2814	Major facilitator Superfamily
BV083_RS04880	COG0747	negative chemotaxis
BV083_RS04885	COG0748	coenzyme F420 binding
BV083_RS04895	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BV083_RS04895	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BV083_RS04910	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BV083_RS04915	COG0542	response to heat
BV083_RS04920	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BV083_RS04925	COG0557	exoribonuclease II activity
BV083_RS04935	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BV083_RS04945	COG1217	gtp-binding protein TYPA
BV083_RS04950	COG0174	glutamine synthetase
BV083_RS04960	COG2244	polysaccharide biosynthetic process
BV083_RS04965	COG0463	Glycosyl transferase, family 2
BV083_RS04970	COG1216	Glycosyl transferase, family 2
BV083_RS04985	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BV083_RS04990	COG1088	dTDP-glucose 4,6-dehydratase activity
BV083_RS04995	COG3307	-O-antigen
BV083_RS05015	COG0697	spore germination
BV083_RS05030	COG0142	geranyltranstransferase activity
BV083_RS05035	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BV083_RS05040	COG1115	amino acid carrier protein
BV083_RS05045	COG0745	RESPONSE REGULATOR receiver
BV083_RS05055	COG2259	Doxx family
BV083_RS05060	COG0138	bifunctional purine biosynthesis protein purh
BV083_RS05065	COG0151	Belongs to the GarS family
BV083_RS05085	COG0237	dephospho-CoA kinase activity
BV083_RS05100	COG1309	transcriptional regulator
BV083_RS05105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BV083_RS05110	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BV083_RS05115	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BV083_RS05120	COG2814	Major facilitator Superfamily
BV083_RS05125	COG1566	PFAM secretion protein HlyD family protein
BV083_RS05130	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BV083_RS05145	COG0730	response to heat
BV083_RS05160	COG0590	tRNA wobble adenosine to inosine editing
BV083_RS05165	COG4701	Protein of unknown function (DUF721)
BV083_RS05180	COG0494	nUDIX hydrolase
BV083_RS05185	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BV083_RS05185	COG0475	glutathione-regulated potassium exporter activity
BV083_RS05190	COG2226	methyltransferase
BV083_RS05210	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
BV083_RS05220	COG0750	zinc metalloprotease
BV083_RS05225	COG0575	Belongs to the CDS family
BV083_RS05230	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BV083_RS05240	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
BV083_RS05245	COG1466	dna polymerase III delta subunit
BV083_RS05255	COG2026	Addiction module toxin, RelE StbE family
BV083_RS05295	COG2852	Protein conserved in bacteria
BV083_RS05300	COG4545	Glutaredoxin-related protein
BV083_RS05310	COG0753	catalase activity
BV083_RS05315	COG0754	glutathionylspermidine amidase activity
BV083_RS05325	COG4316	Uncharacterized protein conserved in bacteria (DUF2251)
BV083_RS05335	COG2081	HI0933 family
BV083_RS05340	COG3088	subunit of a heme lyase
BV083_RS05340	COG4235	cytochrome complex assembly
BV083_RS05345	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BV083_RS05350	COG1138	Cytochrome C-type biogenesis protein
BV083_RS05355	COG0483	inositol monophosphate 1-phosphatase activity
BV083_RS05360	COG2165	general secretion pathway protein
BV083_RS05365	COG4795	General secretion pathway protein
BV083_RS05380	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BV083_RS05390	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BV083_RS05390	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BV083_RS05395	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BV083_RS05405	COG0076	glutamate decarboxylase activity
BV083_RS05410	COG1487	ribonuclease activity
BV083_RS05420	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BV083_RS05435	COG2003	Belongs to the UPF0758 family
BV083_RS05440	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BV083_RS05460	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BV083_RS05475	COG5633	Lipoprotein
BV083_RS05480	COG0537	adenosine 5'-monophosphoramidase activity
BV083_RS05490	COG0196	riboflavin kinase activity
BV083_RS05495	COG0728	peptidoglycan biosynthetic process
BV083_RS05520	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BV083_RS05525	COG1441	menaquinone biosynthetic process
BV083_RS05535	COG0511	ligase activity, forming carbon-carbon bonds
BV083_RS05540	COG0439	Biotin carboxylase
BV083_RS05545	COG3924	membrane
BV083_RS05550	COG4145	pantothenate transmembrane transporter activity
BV083_RS05555	COG0697	spore germination
BV083_RS05560	COG2184	nucleotidyltransferase activity
BV083_RS05570	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BV083_RS05600	COG0758	DNA mediated transformation
BV083_RS05610	COG0473	3-isopropylmalate dehydrogenase activity
BV083_RS05635	COG0592	DNA-directed DNA polymerase activity
BV083_RS05640	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BV083_RS05645	COG4771	TonB-dependent receptor
BV083_RS05645	COG1629	transport
BV083_RS05655	COG4783	chaperone-mediated protein folding
BV083_RS05685	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BV083_RS05690	COG2194	sulfuric ester hydrolase activity
BV083_RS05695	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BV083_RS05705	COG1555	photosystem II stabilization
BV083_RS05710	COG4143	(ABC) transporter
BV083_RS05715	COG1178	ABC-type Fe3 transport system permease component
BV083_RS05720	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
BV083_RS05730	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BV083_RS05740	COG0560	Phosphoserine phosphatase
BV083_RS05755	COG0762	integral membrane protein
BV083_RS05760	COG0121	glutamine amidotransferase
BV083_RS05780	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BV083_RS05780	COG2221	Nitrite and sulphite reductase 4Fe-4S
BV083_RS05785	COG3381	protein complex oligomerization
BV083_RS05790	COG3302	dmso reductase anchor subunit
BV083_RS05795	COG0437	4 iron, 4 sulfur cluster binding
BV083_RS05805	COG1305	Transglutaminase-like
BV083_RS05815	COG2608	mercury ion transmembrane transporter activity
BV083_RS05820	COG1132	(ABC) transporter
BV083_RS05825	COG1917	Cupin 2, conserved barrel domain protein
BV083_RS05825	COG4977	sequence-specific DNA binding
BV083_RS05830	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BV083_RS05835	COG3421	Type III restriction
BV083_RS05845	COG2189	Belongs to the N(4) N(6)-methyltransferase family
BV083_RS05855	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BV083_RS05860	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BV083_RS05865	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BV083_RS05870	COG2194	sulfuric ester hydrolase activity
BV083_RS05880	COG3301	Polysulphide reductase, NrfD
BV083_RS05885	COG0437	4 iron, 4 sulfur cluster binding
BV083_RS05890	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
BV083_RS05895	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
BV083_RS05905	COG1643	Atp-dependent helicase
BV083_RS05910	COG2363	Small membrane protein
BV083_RS05920	COG1294	oxidase, subunit
BV083_RS05925	COG1271	oxidase subunit
BV083_RS05940	COG3201	nicotinamide mononucleotide transporter
BV083_RS05945	COG1126	abc transporter atp-binding protein
BV083_RS05950	COG0765	amino acid transport
BV083_RS05955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BV083_RS05965	COG5007	Belongs to the BolA IbaG family
BV083_RS05970	COG3113	response to antibiotic
BV083_RS05975	COG2854	intermembrane phospholipid transfer
BV083_RS05980	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BV083_RS05985	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BV083_RS05990	COG1127	ABC transporter
BV083_RS05995	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BV083_RS06005	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BV083_RS06010	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BV083_RS06015	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BV083_RS06025	COG1138	Cytochrome C-type biogenesis protein
BV083_RS06030	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BV083_RS06070	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BV083_RS06075	COG2814	Major facilitator Superfamily
BV083_RS06080	COG0859	PFAM glycosyl transferase family 9
BV083_RS06085	COG2207	Transcriptional regulator
BV083_RS06085	COG1609	Transcriptional regulator
BV083_RS06090	COG1757	Na H antiporter
BV083_RS06095	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BV083_RS06100	COG4214	carbohydrate transport
BV083_RS06105	COG1129	ABC transporter
BV083_RS06110	COG4213	ABC transporter substrate-binding protein
BV083_RS06120	COG1070	Carbohydrate kinase
BV083_RS06130	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BV083_RS06140	COG0606	chelatase, subunit chli
BV083_RS06150	COG2990	Protein conserved in bacteria
BV083_RS06155	COG4608	Belongs to the ABC transporter superfamily
BV083_RS06160	COG0444	Belongs to the ABC transporter superfamily
BV083_RS06165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BV083_RS06170	COG0601	transmembrane transport
BV083_RS06175	COG4166	transmembrane transport
BV083_RS06180	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BV083_RS06190	COG1966	Carbon starvation protein
BV083_RS06205	COG3116	cell division
BV083_RS06210	COG0768	penicillin binding
BV083_RS06220	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BV083_RS06235	COG0772	Belongs to the SEDS family
BV083_RS06240	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BV083_RS06255	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BV083_RS06260	COG0849	cell division
BV083_RS06265	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BV083_RS06275	COG0077	Prephenate dehydratase
BV083_RS06275	COG1605	Chorismate mutase
BV083_RS06280	COG1660	Displays ATPase and GTPase activities
BV083_RS06285	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BV083_RS06290	COG1137	ATPase activity
BV083_RS06295	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BV083_RS06300	COG3117	lipopolysaccharide transmembrane transporter activity
BV083_RS06310	COG0312	modulator of DNA gyrase
BV083_RS06315	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BV083_RS06320	COG1280	lysine exporter protein (LysE YggA)
BV083_RS06325	COG1823	symporter activity
BV083_RS06330	COG0602	queuosine metabolic process
BV083_RS06340	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BV083_RS06345	COG4988	ABC transporter
BV083_RS06350	COG0492	ferredoxin-NADP+ reductase activity
BV083_RS06355	COG3118	belongs to the thioredoxin family
BV083_RS06365	COG2050	protein possibly involved in aromatic compounds catabolism
BV083_RS06370	COG0247	lactate metabolic process
BV083_RS06370	COG0277	FAD linked oxidase domain protein
BV083_RS06390	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BV083_RS06400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BV083_RS06405	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BV083_RS06410	COG0512	Glutamine amidotransferase of anthranilate synthase
BV083_RS06420	COG3091	SprT-like family
BV083_RS06425	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BV083_RS06435	COG4160	amino acid transport
BV083_RS06440	COG4215	(ABC) transporter
BV083_RS06445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BV083_RS06450	COG1126	abc transporter atp-binding protein
BV083_RS06460	COG1793	dna ligase
BV083_RS06465	COG4608	Belongs to the ABC transporter superfamily
BV083_RS06470	COG0444	Belongs to the ABC transporter superfamily
BV083_RS06475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BV083_RS06480	COG0601	transmembrane transport
BV083_RS06485	COG0210	DNA helicase
BV083_RS06495	COG0602	queuosine metabolic process
BV083_RS06500	COG0720	synthase
BV083_RS06515	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BV083_RS06520	COG0583	DNA-binding transcription factor activity
BV083_RS06540	COG0009	L-threonylcarbamoyladenylate synthase
BV083_RS06545	COG1187	pseudouridine synthase activity
BV083_RS06550	COG0583	DNA-binding transcription factor activity
BV083_RS06555	COG2890	protein-(glutamine-N5) methyltransferase activity
BV083_RS06560	COG2840	Smr protein MutS2
BV083_RS06565	COG0280	phosphate acetyltransferase
BV083_RS06565	COG0857	belongs to the CobB CobQ family
BV083_RS06580	COG1286	toxin biosynthetic process
BV083_RS06585	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BV083_RS06590	COG1090	epimerase
BV083_RS06600	COG0039	L-malate dehydrogenase activity
BV083_RS06615	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BV083_RS06620	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BV083_RS06625	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BV083_RS06630	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BV083_RS06635	COG4206	TonB-dependent receptor
BV083_RS06635	COG1629	transport
BV083_RS06640	COG1620	l-lactate permease
BV083_RS06650	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BV083_RS06665	COG4172	Belongs to the ABC transporter superfamily
BV083_RS06670	COG4172	Belongs to the ABC transporter superfamily
BV083_RS06675	COG4171	peptide transport system, permease
BV083_RS06680	COG4168	peptide transport system, permease
BV083_RS06685	COG4166	transmembrane transport
BV083_RS06690	COG3106	COG3106 Predicted ATPase
BV083_RS06715	COG0527	aspartate kinase activity
BV083_RS06745	COG0586	Pfam SNARE associated Golgi protein
BV083_RS06750	COG3105	Protein conserved in bacteria
BV083_RS06755	COG0251	oxidation-reduction process
BV083_RS06765	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
BV083_RS06770	COG0789	Transcriptional regulator
BV083_RS06775	COG5266	PFAM Nickel transport complex, NikM subunit, transmembrane
BV083_RS06780	COG0310	cobalt ion transport
BV083_RS06785	COG0310	cobalt ion transport
BV083_RS06790	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BV083_RS06795	COG1122	ATPase activity
BV083_RS06800	COG1448	Aminotransferase
BV083_RS06805	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BV083_RS06810	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BV083_RS06825	COG0308	aminopeptidase N
BV083_RS06830	COG0307	riboflavin synthase, alpha
BV083_RS06835	COG0534	Mate efflux family protein
BV083_RS06850	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BV083_RS06855	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BV083_RS06870	COG4991	sh3 domain protein
BV083_RS06875	COG0306	phosphate transporter
BV083_RS06880	COG1392	Phosphate transport regulator
BV083_RS06885	COG2259	Doxx family
BV083_RS06900	COG3219	Protein conserved in bacteria
BV083_RS06925	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
BV083_RS06940	COG3025	triphosphatase activity
BV083_RS06945	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BV083_RS06950	COG1522	sequence-specific DNA binding
BV083_RS06955	COG1674	ftsk spoiiie
BV083_RS06965	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BV083_RS06985	COG0788	formyltetrahydrofolate deformylase activity
BV083_RS06990	COG2916	Histone family protein nucleoid-structuring protein H-NS
BV083_RS06995	COG1757	Na H antiporter
BV083_RS07005	COG0028	Belongs to the TPP enzyme family
BV083_RS07010	COG0440	acetolactate synthase activity
BV083_RS07020	COG3102	Protein conserved in bacteria
BV083_RS07030	COG3133	Outer membrane lipoprotein
BV083_RS07035	COG1216	Glycosyl transferase, family 2
BV083_RS07050	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BV083_RS07055	COG0305	Participates in initiation and elongation during chromosome replication
BV083_RS07060	COG0469	pyruvate kinase activity
BV083_RS07085	COG4383	Mu-like prophage protein gp29
BV083_RS07090	COG2369	cell adhesion
BV083_RS07100	COG5005	Phage virion morphogenesis
BV083_RS07110	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BV083_RS07115	COG3101	peptidyl-lysine hydroxylation
BV083_RS07125	COG2333	competence protein COMEC
BV083_RS07125	COG0658	competence protein
BV083_RS07140	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BV083_RS07145	COG1714	RDD family
BV083_RS07150	COG2890	protein-(glutamine-N5) methyltransferase activity
BV083_RS07155	COG2912	Transglutaminase-like superfamily
BV083_RS07165	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BV083_RS07170	COG4591	ABC-type transport system involved in lipoprotein release permease component
BV083_RS07175	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BV083_RS07185	COG2830	Protein of unknown function (DUF452)
BV083_RS07190	COG0500	methyltransferase
BV083_RS07195	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BV083_RS07200	COG1136	(ABC) transporter
BV083_RS07205	COG4591	ABC-type transport system involved in lipoprotein release permease component
BV083_RS07210	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BV083_RS07215	COG2932	Transcriptional regulator
BV083_RS07225	COG2249	NAD(P)H dehydrogenase (quinone) activity
BV083_RS07230	COG3381	protein complex oligomerization
BV083_RS07235	COG0778	Nitroreductase
BV083_RS07240	COG0616	signal peptide processing
BV083_RS07245	COG3475	LICD family
BV083_RS07250	COG4750	Nucleotidyl transferase
BV083_RS07255	COG0697	spore germination
BV083_RS07260	COG0510	thiamine kinase activity
BV083_RS07275	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BV083_RS07280	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BV083_RS07285	COG0189	ligase activity
BV083_RS07290	COG0786	glutamate:sodium symporter activity
BV083_RS07295	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BV083_RS07300	COG0187	DNA topoisomerase II activity
BV083_RS07305	COG1560	Kdo2-lipid A biosynthetic process
BV083_RS07310	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BV083_RS07310	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BV083_RS07315	COG0725	ABC transporter, periplasmic molybdate-binding protein
BV083_RS07320	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BV083_RS07330	COG0157	Belongs to the NadC ModD family
BV083_RS07335	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BV083_RS07340	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BV083_RS07345	COG1120	ATPase activity
BV083_RS07350	COG0725	ABC transporter, periplasmic molybdate-binding protein
BV083_RS07355	COG4178	(ABC) transporter
BV083_RS07360	COG4774	siderophore transport
BV083_RS07370	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BV083_RS07390	COG2166	iron-sulfur cluster assembly
BV083_RS07400	COG0488	(ABC) transporter
BV083_RS07405	COG0488	(ABC) transporter
BV083_RS07410	COG0288	reversible hydration of carbon dioxide
BV083_RS07430	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BV083_RS07435	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BV083_RS07440	COG1280	lysine exporter protein (LysE YggA)
BV083_RS07445	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BV083_RS07450	COG0633	Ferredoxin
BV083_RS07475	COG0791	NLP P60 protein
BV083_RS07485	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
BV083_RS07490	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BV083_RS07510	COG1674	ftsk spoiiie
BV083_RS07515	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BV083_RS07535	COG3119	arylsulfatase activity
BV083_RS07540	COG0676	glucose-6-phosphate 1-epimerase activity
BV083_RS07550	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BV083_RS07555	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BV083_RS07560	COG1074	ATP-dependent DNA helicase activity
BV083_RS07565	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BV083_RS07575	COG1067	ATP-dependent peptidase activity
BV083_RS07585	COG0515	serine threonine protein kinase
BV083_RS07605	COG2027	D-alanyl-D-alanine carboxypeptidase
BV083_RS07610	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BV083_RS07615	COG1534	Rna-binding protein
BV083_RS07625	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BV083_RS07630	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BV083_RS07640	COG2062	phosphohistidine phosphatase, SixA
BV083_RS07650	COG1538	Outer membrane efflux protein
BV083_RS07665	COG1595	DNA-templated transcription, initiation
BV083_RS07680	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BV083_RS07680	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BV083_RS07685	COG0785	Cytochrome C biogenesis protein
BV083_RS07690	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BV083_RS07700	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BV083_RS07705	COG0303	'Molybdopterin
BV083_RS07720	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BV083_RS07725	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BV083_RS07740	COG0625	glutathione transferase activity
BV083_RS07745	COG2969	positive regulation of protein catabolic process
BV083_RS07755	COG0142	geranyltranstransferase activity
BV083_RS07770	COG3098	single-species biofilm formation
BV083_RS07775	COG0564	pseudouridine synthase activity
BV083_RS07785	COG1278	Cold shock
BV083_RS07790	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BV083_RS07795	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BV083_RS07810	COG4221	oxidoreductase activity
BV083_RS07820	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BV083_RS07825	COG5266	PFAM Nickel transport complex, NikM subunit, transmembrane
BV083_RS07830	COG0589	response to stress
BV083_RS07835	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BV083_RS07855	COG3561	AntA/AntB antirepressor
BV083_RS07945	COG0613	PHP domain protein
BV083_RS07950	COG2268	Band 7 protein
BV083_RS07955	COG0114	fumarate hydratase activity
BV083_RS07965	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BV083_RS07970	COG2927	DNA polymerase III (CHI subunit)
BV083_RS07975	COG4185	zeta toxin
BV083_RS07995	COG0525	valine-tRNA ligase activity
BV083_RS08000	COG0298	carbon dioxide binding
BV083_RS08005	COG0134	indole-3-glycerol-phosphate synthase activity
BV083_RS08005	COG0135	phosphoribosylanthranilate isomerase activity
BV083_RS08015	COG1942	4-Oxalocrotonate Tautomerase
BV083_RS08020	COG0512	Glutamine amidotransferase of anthranilate synthase
BV083_RS08025	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BV083_RS08035	COG1528	Iron-storage protein
BV083_RS08040	COG1528	Iron-storage protein
BV083_RS08045	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BV083_RS08050	COG0573	inorganic phosphate transmembrane transporter activity
BV083_RS08055	COG0581	inorganic phosphate transmembrane transporter activity
BV083_RS08065	COG0745	RESPONSE REGULATOR receiver
BV083_RS08070	COG5002	protein histidine kinase activity
BV083_RS08075	COG2925	Exonuclease
BV083_RS08080	COG0697	spore germination
BV083_RS08085	COG3586	endonuclease activity
BV083_RS08095	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
BV083_RS08110	COG2920	part of a sulfur-relay system
BV083_RS08115	COG3585	molybdate ion transport
BV083_RS08125	COG0612	Peptidase, M16
BV083_RS08140	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BV083_RS08145	COG0583	DNA-binding transcription factor activity
BV083_RS08150	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BV083_RS08155	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BV083_RS08160	COG0058	SHG alpha-glucan phosphorylase activity
BV083_RS08170	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BV083_RS08175	COG1523	belongs to the glycosyl hydrolase 13 family
BV083_RS08180	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BV083_RS08185	COG1640	4-alpha-glucanotransferase
BV083_RS08190	COG2983	Belongs to the UPF0260 family
BV083_RS08200	COG1530	ribonuclease E activity
BV083_RS08205	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BV083_RS08220	COG0783	Belongs to the Dps family
BV083_RS08235	COG1176	ABC-type spermidine putrescine transport system, permease component I
BV083_RS08240	COG1177	transmembrane transport
BV083_RS08245	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BV083_RS08250	COG0488	(ABC) transporter
BV083_RS08260	COG1346	cytolysis
BV083_RS08270	COG1525	nuclease
BV083_RS08275	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BV083_RS08280	COG2166	iron-sulfur cluster assembly
BV083_RS08285	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
BV083_RS08295	COG0287	Prephenate dehydrogenase
BV083_RS08295	COG1605	Chorismate mutase
BV083_RS08310	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BV083_RS08315	COG0732	type I restriction modification DNA specificity domain
BV083_RS08330	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BV083_RS08335	COG0195	Participates in both transcription termination and antitermination
BV083_RS08360	COG1083	cytidylyl-transferase
BV083_RS08370	COG0489	protein tyrosine kinase activity
BV083_RS08385	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BV083_RS08390	COG0500	methyltransferase
BV083_RS08400	COG1944	ATP diphosphatase activity
BV083_RS08410	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BV083_RS08415	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BV083_RS08420	COG2949	membrane
BV083_RS08425	COG0285	dihydrofolate synthase activity
BV083_RS08435	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BV083_RS08440	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BV083_RS08445	COG1444	tRNA N-acetyltransferase activity
BV083_RS08450	COG3094	Invasion gene expression up-regulator, SirB
BV083_RS08455	COG0488	(ABC) transporter
BV083_RS08460	COG3093	addiction module antidote protein HigA
BV083_RS08465	COG3549	Plasmid maintenance system killer
BV083_RS08470	COG3683	transport system, periplasmic component
BV083_RS08475	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
BV083_RS08490	COG1368	sulfuric ester hydrolase activity
BV083_RS08495	COG0281	malic enzyme
BV083_RS08495	COG0280	phosphate acetyltransferase
BV083_RS08500	COG3955	Domain of unknown function (DUF1919)
BV083_RS08505	COG1187	pseudouridine synthase activity
BV083_RS08510	COG2814	Major facilitator Superfamily
BV083_RS08520	COG2860	membrane
BV083_RS08530	COG0484	heat shock protein binding
BV083_RS08540	COG5339	Protein conserved in bacteria
BV083_RS08550	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BV083_RS08555	COG0508	dehydrogenase complex catalyzes the overall conversion of
BV083_RS08560	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BV083_RS08570	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BV083_RS08580	COG2233	PERMEase
BV083_RS08585	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BV083_RS08590	COG0023	Translation Initiation Factor
BV083_RS08600	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BV083_RS08605	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
BV083_RS08615	COG0539	negative regulation of cytoplasmic translation
BV083_RS08620	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BV083_RS08635	COG0277	FAD linked oxidase domain protein
BV083_RS08640	COG2198	Histidine kinase
BV083_RS08650	COG0791	NLP P60 protein
BV083_RS08660	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BV083_RS08665	COG3107	peptidoglycan biosynthetic process
BV083_RS08675	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BV083_RS08680	COG2823	Periplasmic or secreted lipoprotein
BV083_RS08685	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BV083_RS08690	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BV083_RS08695	COG0508	dehydrogenase complex catalyzes the overall conversion of
BV083_RS08700	COG0567	Dehydrogenase, E1 component
BV083_RS08705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BV083_RS08710	COG0084	hydrolase, TatD family'
BV083_RS08715	COG3108	Peptidase M15
BV083_RS08720	COG2989	Protein conserved in bacteria
BV083_RS08725	COG0793	Belongs to the peptidase S41A family
BV083_RS08735	COG2995	paraquat-inducible protein a
BV083_RS08740	COG3008	intermembrane lipid transfer
BV083_RS08745	COG0314	molybdopterin synthase activity
BV083_RS08750	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BV083_RS08765	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
BV083_RS08775	COG0517	IMP dehydrogenase activity
BV083_RS08775	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BV083_RS08780	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BV083_RS08795	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
BV083_RS08800	COG1289	transmembrane transporter activity
BV083_RS08810	COG0616	signal peptide processing
BV083_RS08845	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BV083_RS08850	COG0733	neurotransmitter:sodium symporter activity
BV083_RS08855	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BV083_RS08860	COG4149	molybdate abc transporter
BV083_RS08865	COG0725	ABC transporter, periplasmic molybdate-binding protein
BV083_RS08870	COG2005	Transcriptional regulator
BV083_RS08875	COG1216	Glycosyl transferase, family 2
BV083_RS08880	COG1216	Glycosyl transferase, family 2
BV083_RS08885	COG3306	glycosyltransferase involved in LPS biosynthesis
BV083_RS08890	COG0438	transferase activity, transferring glycosyl groups
BV083_RS08900	COG2244	polysaccharide biosynthetic process
BV083_RS08905	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BV083_RS08915	COG0795	lipopolysaccharide-transporting ATPase activity
BV083_RS08920	COG0795	lipopolysaccharide-transporting ATPase activity
BV083_RS08930	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BV083_RS08935	COG0642	Histidine kinase
BV083_RS08940	COG0745	RESPONSE REGULATOR receiver
BV083_RS08945	COG3111	PFAM Bacterial OB fold (BOF) protein
BV083_RS08955	COG2190	(PTS) system
BV083_RS08960	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BV083_RS08965	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BV083_RS08985	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BV083_RS08995	COG0024	Methionine aminopeptidase
BV083_RS09005	COG3112	Uncharacterised protein family (UPF0231)
BV083_RS09010	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BV083_RS09025	COG1914	H( )-stimulated, divalent metal cation uptake system
BV083_RS09035	COG1984	allophanate hydrolase subunit 2
BV083_RS09040	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BV083_RS09050	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BV083_RS09065	COG1687	branched-chain amino acid
BV083_RS09070	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BV083_RS09075	COG0583	DNA-binding transcription factor activity
BV083_RS09115	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BV083_RS09120	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BV083_RS09130	COG0194	GDP metabolic process