locus-tag	class	description
DLK00_RS00015	COG3585	molybdate ion transport
DLK00_RS00020	COG2920	part of a sulfur-relay system
DLK00_RS00025	COG0037	tRNA processing
DLK00_RS00030	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
DLK00_RS00035	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
DLK00_RS00040	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
DLK00_RS00050	COG0697	spore germination
DLK00_RS00060	COG5002	protein histidine kinase activity
DLK00_RS00065	COG0745	RESPONSE REGULATOR receiver
DLK00_RS00085	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DLK00_RS00090	COG1528	Iron-storage protein
DLK00_RS00095	COG1528	Iron-storage protein
DLK00_RS00110	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DLK00_RS00115	COG0512	Glutamine amidotransferase of anthranilate synthase
DLK00_RS00120	COG1942	4-Oxalocrotonate Tautomerase
DLK00_RS00130	COG0134	indole-3-glycerol-phosphate synthase activity
DLK00_RS00130	COG0135	phosphoribosylanthranilate isomerase activity
DLK00_RS00135	COG0298	carbon dioxide binding
DLK00_RS00160	COG4185	zeta toxin
DLK00_RS00165	COG2927	DNA polymerase III (CHI subunit)
DLK00_RS00170	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DLK00_RS00180	COG2801	Transposase and inactivated derivatives
DLK00_RS00190	COG0114	fumarate hydratase activity
DLK00_RS00195	COG2268	Band 7 protein
DLK00_RS00200	COG0613	PHP domain protein
DLK00_RS00210	COG5301	cellulose 1,4-beta-cellobiosidase activity
DLK00_RS00225	COG3728	DNA packaging
DLK00_RS00345	COG3561	AntA/AntB antirepressor
DLK00_RS00350	COG0582	viral genome integration into host DNA
DLK00_RS00360	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DLK00_RS00365	COG0589	response to stress
DLK00_RS00370	COG5266	PFAM Nickel transport complex, NikM subunit, transmembrane
DLK00_RS00375	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DLK00_RS00385	COG4221	oxidoreductase activity
DLK00_RS00400	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DLK00_RS00405	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DLK00_RS00410	COG1278	Cold shock
DLK00_RS00420	COG0564	pseudouridine synthase activity
DLK00_RS00425	COG3098	single-species biofilm formation
DLK00_RS00440	COG0142	geranyltranstransferase activity
DLK00_RS00450	COG2969	positive regulation of protein catabolic process
DLK00_RS00455	COG0625	glutathione transferase activity
DLK00_RS00470	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DLK00_RS00475	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DLK00_RS00485	COG0302	gtp cyclohydrolase
DLK00_RS00490	COG0303	'Molybdopterin
DLK00_RS00495	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DLK00_RS00500	COG3099	Belongs to the UPF0263 family
DLK00_RS00505	COG2431	L-lysine efflux transmembrane transporter activity
DLK00_RS00510	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DLK00_RS00515	COG0785	Cytochrome C biogenesis protein
DLK00_RS00535	COG1595	DNA-templated transcription, initiation
DLK00_RS00550	COG1538	Outer membrane efflux protein
DLK00_RS00570	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DLK00_RS00575	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DLK00_RS00580	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
DLK00_RS00595	COG2801	Transposase and inactivated derivatives
DLK00_RS00605	COG2027	D-alanyl-D-alanine carboxypeptidase
DLK00_RS00610	COG4774	siderophore transport
DLK00_RS00615	COG2801	Transposase and inactivated derivatives
DLK00_RS00625	COG4178	(ABC) transporter
DLK00_RS00640	COG0515	serine threonine protein kinase
DLK00_RS00660	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DLK00_RS00665	COG1074	ATP-dependent DNA helicase activity
DLK00_RS00670	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DLK00_RS00675	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DLK00_RS00685	COG0676	glucose-6-phosphate 1-epimerase activity
DLK00_RS00690	COG3119	arylsulfatase activity
DLK00_RS00695	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DLK00_RS00710	COG0631	protein serine/threonine phosphatase activity
DLK00_RS00715	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DLK00_RS00720	COG1674	ftsk spoiiie
DLK00_RS00730	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DLK00_RS00735	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
DLK00_RS00745	COG0791	NLP P60 protein
DLK00_RS00750	COG0776	regulation of translation
DLK00_RS00770	COG0633	Ferredoxin
DLK00_RS00780	COG1280	lysine exporter protein (LysE YggA)
DLK00_RS00810	COG0288	reversible hydration of carbon dioxide
DLK00_RS00815	COG0488	(ABC) transporter
DLK00_RS00820	COG0488	(ABC) transporter
DLK00_RS00830	COG1346	cytolysis
DLK00_RS00840	COG1525	nuclease
DLK00_RS00845	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DLK00_RS00850	COG2166	iron-sulfur cluster assembly
DLK00_RS00855	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
DLK00_RS00865	COG0287	Prephenate dehydrogenase
DLK00_RS00865	COG1605	Chorismate mutase
DLK00_RS00885	COG0732	type I restriction modification DNA specificity domain
DLK00_RS00905	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DLK00_RS00910	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DLK00_RS00945	COG3311	Transcriptional regulator
DLK00_RS01015	COG0489	protein tyrosine kinase activity
DLK00_RS01035	COG0500	methyltransferase
DLK00_RS01080	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DLK00_RS01085	COG2949	membrane
DLK00_RS01100	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DLK00_RS01105	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DLK00_RS01120	COG3094	Invasion gene expression up-regulator, SirB
DLK00_RS01125	COG0488	(ABC) transporter
DLK00_RS01130	COG3093	addiction module antidote protein HigA
DLK00_RS01135	COG3549	Plasmid maintenance system killer
DLK00_RS01140	COG3683	transport system, periplasmic component
DLK00_RS01145	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
DLK00_RS01165	COG0281	malic enzyme
DLK00_RS01165	COG0280	phosphate acetyltransferase
DLK00_RS01170	COG3955	Domain of unknown function (DUF1919)
DLK00_RS01175	COG1187	pseudouridine synthase activity
DLK00_RS01180	COG2814	Major facilitator Superfamily
DLK00_RS01190	COG2860	membrane
DLK00_RS01210	COG5339	Protein conserved in bacteria
DLK00_RS01220	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
DLK00_RS01225	COG0508	dehydrogenase complex catalyzes the overall conversion of
DLK00_RS01230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DLK00_RS01240	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DLK00_RS01250	COG2233	PERMEase
DLK00_RS01255	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DLK00_RS01260	COG0023	Translation Initiation Factor
DLK00_RS01270	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
DLK00_RS01275	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
DLK00_RS01285	COG0539	negative regulation of cytoplasmic translation
DLK00_RS01290	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DLK00_RS01305	COG0277	FAD linked oxidase domain protein
DLK00_RS01320	COG0791	NLP P60 protein
DLK00_RS01330	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DLK00_RS01345	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
DLK00_RS01350	COG2823	Periplasmic or secreted lipoprotein
DLK00_RS01365	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DLK00_RS01370	COG0508	dehydrogenase complex catalyzes the overall conversion of
DLK00_RS01380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DLK00_RS01390	COG3108	Peptidase M15
DLK00_RS01395	COG2989	Protein conserved in bacteria
DLK00_RS01420	COG0314	molybdopterin synthase activity
DLK00_RS01425	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
DLK00_RS01440	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
DLK00_RS01450	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DLK00_RS01450	COG0517	IMP dehydrogenase activity
DLK00_RS01455	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DLK00_RS01470	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
DLK00_RS01495	COG3219	Protein conserved in bacteria
DLK00_RS01510	COG2259	Doxx family
DLK00_RS01515	COG1392	Phosphate transport regulator
DLK00_RS01520	COG0306	phosphate transporter
DLK00_RS01525	COG4991	sh3 domain protein
DLK00_RS01545	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DLK00_RS01560	COG0534	Mate efflux family protein
DLK00_RS01585	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DLK00_RS01590	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DLK00_RS01595	COG1448	Aminotransferase
DLK00_RS01600	COG1122	ATPase activity
DLK00_RS01615	COG0310	cobalt ion transport
DLK00_RS01620	COG5266	PFAM Nickel transport complex, NikM subunit, transmembrane
DLK00_RS01640	COG0251	oxidation-reduction process
DLK00_RS01645	COG3105	Protein conserved in bacteria
DLK00_RS01680	COG0527	aspartate kinase activity
DLK00_RS01705	COG3106	COG3106 Predicted ATPase
DLK00_RS01710	COG4166	transmembrane transport
DLK00_RS01720	COG4171	peptide transport system, permease
DLK00_RS01725	COG4172	Belongs to the ABC transporter superfamily
DLK00_RS01730	COG4172	Belongs to the ABC transporter superfamily
DLK00_RS01755	COG1620	l-lactate permease
DLK00_RS01770	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DLK00_RS01780	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DLK00_RS01805	COG1090	epimerase
DLK00_RS01810	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DLK00_RS01815	COG1286	toxin biosynthetic process
DLK00_RS01830	COG0280	phosphate acetyltransferase
DLK00_RS01830	COG0857	belongs to the CobB CobQ family
DLK00_RS01835	COG2840	Smr protein MutS2
DLK00_RS01845	COG0583	DNA-binding transcription factor activity
DLK00_RS01850	COG1187	pseudouridine synthase activity
DLK00_RS01855	COG0009	L-threonylcarbamoyladenylate synthase
DLK00_RS01860	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DLK00_RS01870	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
DLK00_RS01875	COG0583	DNA-binding transcription factor activity
DLK00_RS01880	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DLK00_RS01895	COG0720	synthase
DLK00_RS01900	COG0602	queuosine metabolic process
DLK00_RS01910	COG0210	DNA helicase
DLK00_RS01920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DLK00_RS01930	COG4608	Belongs to the ABC transporter superfamily
DLK00_RS01945	COG1126	abc transporter atp-binding protein
DLK00_RS01950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DLK00_RS01955	COG4215	(ABC) transporter
DLK00_RS01960	COG4160	amino acid transport
DLK00_RS01970	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DLK00_RS01975	COG3091	SprT-like family
DLK00_RS01985	COG0512	Glutamine amidotransferase of anthranilate synthase
DLK00_RS01995	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DLK00_RS02005	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DLK00_RS02020	COG2885	chlorophyll binding
DLK00_RS02020	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DLK00_RS02025	COG0247	lactate metabolic process
DLK00_RS02025	COG0277	FAD linked oxidase domain protein
DLK00_RS02035	COG2852	Protein conserved in bacteria
DLK00_RS02045	COG2050	protein possibly involved in aromatic compounds catabolism
DLK00_RS02055	COG3118	belongs to the thioredoxin family
DLK00_RS02060	COG0492	ferredoxin-NADP+ reductase activity
DLK00_RS02065	COG4988	ABC transporter
DLK00_RS02070	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DLK00_RS02085	COG1823	symporter activity
DLK00_RS02095	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DLK00_RS02100	COG0312	modulator of DNA gyrase
DLK00_RS02110	COG3117	lipopolysaccharide transmembrane transporter activity
DLK00_RS02115	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
DLK00_RS02120	COG1137	ATPase activity
DLK00_RS02125	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DLK00_RS02130	COG1660	Displays ATPase and GTPase activities
DLK00_RS02135	COG0077	Prephenate dehydratase
DLK00_RS02135	COG1605	Chorismate mutase
DLK00_RS02145	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DLK00_RS02150	COG0849	cell division
DLK00_RS02170	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DLK00_RS02175	COG0772	Belongs to the SEDS family
DLK00_RS02180	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DLK00_RS02200	COG0768	penicillin binding
DLK00_RS02205	COG3116	cell division
DLK00_RS02210	COG0275	rRNA processing
DLK00_RS02220	COG1966	Carbon starvation protein
DLK00_RS02235	COG4166	transmembrane transport
DLK00_RS02240	COG0601	transmembrane transport
DLK00_RS02250	COG0444	Belongs to the ABC transporter superfamily
DLK00_RS02255	COG4608	Belongs to the ABC transporter superfamily
DLK00_RS02260	COG2990	Protein conserved in bacteria
DLK00_RS02290	COG3392	D12 class N6 adenine-specific DNA methyltransferase
DLK00_RS02295	COG4416	COG NOG18757 non supervised orthologous group
DLK00_RS02430	COG4373	Mu-like prophage FluMu protein gp28
DLK00_RS02520	COG3409	Peptidoglycan-binding domain 1 protein
DLK00_RS02520	COG3267	Type II secretory pathway component ExeA
DLK00_RS02530	COG4396	Host-nuclease inhibitor protein Gam
DLK00_RS02555	COG4382	Mu-like prophage protein Gp16
DLK00_RS02565	COG4783	chaperone-mediated protein folding
DLK00_RS02575	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DLK00_RS02580	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DLK00_RS02590	COG2814	Major facilitator Superfamily
DLK00_RS02595	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DLK00_RS02635	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DLK00_RS02640	COG1138	Cytochrome C-type biogenesis protein
DLK00_RS02650	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DLK00_RS02655	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DLK00_RS02660	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DLK00_RS02670	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DLK00_RS02680	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DLK00_RS02685	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DLK00_RS02690	COG2854	intermembrane phospholipid transfer
DLK00_RS02695	COG3113	response to antibiotic
DLK00_RS02700	COG5007	Belongs to the BolA IbaG family
DLK00_RS02710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DLK00_RS02715	COG0765	amino acid transport
DLK00_RS02720	COG1126	abc transporter atp-binding protein
DLK00_RS02725	COG3201	nicotinamide mononucleotide transporter
DLK00_RS02740	COG1271	oxidase subunit
DLK00_RS02745	COG1294	oxidase, subunit
DLK00_RS02755	COG2363	Small membrane protein
DLK00_RS02760	COG1643	Atp-dependent helicase
DLK00_RS02775	COG1643	Atp-dependent helicase
DLK00_RS02780	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
DLK00_RS02785	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
DLK00_RS02805	COG2194	sulfuric ester hydrolase activity
DLK00_RS02810	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DLK00_RS02815	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DLK00_RS02835	COG3421	Type III restriction
DLK00_RS02840	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DLK00_RS02845	COG4977	sequence-specific DNA binding
DLK00_RS02845	COG1917	Cupin 2, conserved barrel domain protein
DLK00_RS02850	COG1132	(ABC) transporter
DLK00_RS02855	COG2608	mercury ion transmembrane transporter activity
DLK00_RS02875	COG0437	4 iron, 4 sulfur cluster binding
DLK00_RS02880	COG3302	dmso reductase anchor subunit
DLK00_RS02885	COG3381	protein complex oligomerization
DLK00_RS02890	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DLK00_RS02890	COG2221	Nitrite and sulphite reductase 4Fe-4S
DLK00_RS02905	COG1373	ATPase (AAA superfamily
DLK00_RS02915	COG0762	integral membrane protein
DLK00_RS02930	COG0560	Phosphoserine phosphatase
DLK00_RS02940	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DLK00_RS02955	COG1178	ABC-type Fe3 transport system permease component
DLK00_RS02965	COG1555	photosystem II stabilization
DLK00_RS02975	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DLK00_RS02980	COG2194	sulfuric ester hydrolase activity
DLK00_RS02990	COG2801	Transposase and inactivated derivatives
DLK00_RS02995	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DLK00_RS03015	COG0594	ribonuclease P activity
DLK00_RS03035	COG1629	transport
DLK00_RS03035	COG4771	TonB-dependent receptor
DLK00_RS03040	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DLK00_RS03045	COG0592	DNA-directed DNA polymerase activity
DLK00_RS03050	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DLK00_RS03060	COG0066	3-isopropylmalate dehydratase activity
DLK00_RS03075	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DLK00_RS03080	COG0758	DNA mediated transformation
DLK00_RS03110	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DLK00_RS03120	COG0697	spore germination
DLK00_RS03125	COG4145	pantothenate transmembrane transporter activity
DLK00_RS03130	COG3924	membrane
DLK00_RS03135	COG0439	Biotin carboxylase
DLK00_RS03140	COG0511	ligase activity, forming carbon-carbon bonds
DLK00_RS03150	COG1441	menaquinone biosynthetic process
DLK00_RS03155	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DLK00_RS03195	COG0537	adenosine 5'-monophosphoramidase activity
DLK00_RS03200	COG5633	Lipoprotein
DLK00_RS03205	COG1472	Belongs to the glycosyl hydrolase 3 family
DLK00_RS03215	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DLK00_RS03240	COG2003	Belongs to the UPF0758 family
DLK00_RS03260	COG0076	glutamate decarboxylase activity
DLK00_RS03285	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
DLK00_RS03300	COG4795	General secretion pathway protein
DLK00_RS03305	COG2165	general secretion pathway protein
DLK00_RS03310	COG0483	inositol monophosphate 1-phosphatase activity
DLK00_RS03320	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DLK00_RS03330	COG2081	HI0933 family
DLK00_RS03340	COG4316	Uncharacterized protein conserved in bacteria (DUF2251)
DLK00_RS03350	COG0754	glutathionylspermidine amidase activity
DLK00_RS03355	COG0753	catalase activity
DLK00_RS03365	COG4545	Glutaredoxin-related protein
DLK00_RS03370	COG2852	Protein conserved in bacteria
DLK00_RS03375	COG0751	glycine-tRNA ligase activity
DLK00_RS03405	COG2026	Addiction module toxin, RelE StbE family
DLK00_RS03415	COG1466	dna polymerase III delta subunit
DLK00_RS03420	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
DLK00_RS03430	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DLK00_RS03450	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
DLK00_RS03470	COG2226	methyltransferase
DLK00_RS03475	COG0475	glutathione-regulated potassium exporter activity
DLK00_RS03475	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DLK00_RS03495	COG4701	Protein of unknown function (DUF721)
DLK00_RS03500	COG0590	tRNA wobble adenosine to inosine editing
DLK00_RS03515	COG0730	response to heat
DLK00_RS03535	COG1566	PFAM secretion protein HlyD family protein
DLK00_RS03540	COG2814	Major facilitator Superfamily
DLK00_RS03545	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DLK00_RS03550	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DLK00_RS03555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DLK00_RS03560	COG1309	transcriptional regulator
DLK00_RS03565	COG2801	Transposase and inactivated derivatives
DLK00_RS03575	COG0513	Belongs to the DEAD box helicase family
DLK00_RS03610	COG2259	Doxx family
DLK00_RS03620	COG0745	RESPONSE REGULATOR receiver
DLK00_RS03630	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DLK00_RS03635	COG0142	geranyltranstransferase activity
DLK00_RS03650	COG0697	spore germination
DLK00_RS03670	COG3307	-O-antigen
DLK00_RS03675	COG1088	dTDP-glucose 4,6-dehydratase activity
DLK00_RS03680	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DLK00_RS03700	COG1216	Glycosyl transferase, family 2
DLK00_RS03720	COG0174	glutamine synthetase
DLK00_RS03730	COG1217	gtp-binding protein TYPA
DLK00_RS03740	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
DLK00_RS03755	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DLK00_RS03760	COG0542	response to heat
DLK00_RS03780	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DLK00_RS03780	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DLK00_RS03805	COG4245	von Willebrand factor, type A
DLK00_RS03840	COG0748	coenzyme F420 binding
DLK00_RS03845	COG0747	negative chemotaxis
DLK00_RS03850	COG2814	Major facilitator Superfamily
DLK00_RS03855	COG1763	Mo-molybdopterin cofactor biosynthetic process
DLK00_RS03865	COG3086	response to oxidative stress
DLK00_RS03875	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DLK00_RS03880	COG3085	chromosome segregation
DLK00_RS03885	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DLK00_RS03890	COG3084	Protein conserved in bacteria
DLK00_RS03900	COG0402	S-adenosylhomocysteine deaminase activity
DLK00_RS03905	COG3083	sulfuric ester hydrolase activity
DLK00_RS03920	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DLK00_RS03925	COG0745	RESPONSE REGULATOR receiver
DLK00_RS03935	COG1053	succinate dehydrogenase
DLK00_RS03940	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DLK00_RS03945	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
DLK00_RS03950	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
DLK00_RS03955	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DLK00_RS03965	COG0741	lytic transglycosylase activity
DLK00_RS03970	COG2350	Protein conserved in bacteria
DLK00_RS03975	COG1607	acyl-coa hydrolase
DLK00_RS03990	COG4211	Belongs to the binding-protein-dependent transport system permease family
DLK00_RS03995	COG1129	ABC transporter
DLK00_RS04000	COG1879	ABC-type sugar transport system periplasmic component
DLK00_RS04005	COG1609	Transcriptional regulator
DLK00_RS04010	COG1085	galactose-1-phosphate uridylyltransferase
DLK00_RS04015	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DLK00_RS04020	COG2017	converts alpha-aldose to the beta-anomer
DLK00_RS04030	COG0006	proline dipeptidase activity
DLK00_RS04035	COG0589	response to stress
DLK00_RS04050	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DLK00_RS04085	COG0641	radical SAM
DLK00_RS04125	COG0201	protein transport
DLK00_RS04210	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DLK00_RS04230	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DLK00_RS04235	COG0051	transcription antitermination factor activity, RNA binding
DLK00_RS04240	COG0583	DNA-binding transcription factor activity
DLK00_RS04245	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DLK00_RS04250	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DLK00_RS04255	COG2031	fatty acid transporter
DLK00_RS04260	COG0183	Belongs to the thiolase family
DLK00_RS04265	COG2177	Part of the ABC transporter FtsEX involved in
DLK00_RS04270	COG2884	Cell division ATP-binding protein ftsE
DLK00_RS04300	COG3172	ATPase kinase involved in NAD metabolism
DLK00_RS04330	COG1194	a g-specific adenine glycosylase
DLK00_RS04345	COG4942	peptidase
DLK00_RS04350	COG2861	carbohydrate metabolic process
DLK00_RS04375	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DLK00_RS04380	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DLK00_RS04400	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
DLK00_RS04405	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DLK00_RS04410	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
DLK00_RS04415	COG0702	epimerase
DLK00_RS04425	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DLK00_RS04435	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DLK00_RS04445	COG0028	Belongs to the TPP enzyme family
DLK00_RS04465	COG0204	Acyl-transferase
DLK00_RS04495	COG0019	diaminopimelate decarboxylase activity
DLK00_RS04500	COG2197	response regulator
DLK00_RS04535	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DLK00_RS04540	COG1739	Uncharacterized protein family UPF0029
DLK00_RS04545	COG0425	Belongs to the sulfur carrier protein TusA family
DLK00_RS04555	COG2801	Transposase and inactivated derivatives
DLK00_RS04575	COG2962	Rard protein
DLK00_RS04580	COG0583	DNA-binding transcription factor activity
DLK00_RS04605	COG2271	Major facilitator Superfamily
DLK00_RS04610	COG0584	glycerophosphoryl diester phosphodiesterase
DLK00_RS04615	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DLK00_RS04620	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DLK00_RS04625	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
DLK00_RS04630	COG0584	glycerophosphoryl diester phosphodiesterase
DLK00_RS04635	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
DLK00_RS04650	COG2801	Transposase and inactivated derivatives
DLK00_RS04655	COG1187	pseudouridine synthase activity
DLK00_RS04670	COG0729	surface antigen
DLK00_RS04675	COG1047	Peptidyl-prolyl cis-trans
DLK00_RS04680	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
DLK00_RS04690	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
DLK00_RS04695	COG1238	metal cluster binding
DLK00_RS04705	COG4942	peptidase
DLK00_RS04705	COG1388	LysM domain
DLK00_RS04735	COG1921	L-seryl-tRNASec selenium transferase activity
DLK00_RS04740	COG3276	selenocysteine insertion sequence binding
DLK00_RS04750	COG3077	Addiction module antitoxin, RelB DinJ family
DLK00_RS04755	COG3041	Addiction module toxin RelE StbE family
DLK00_RS04765	COG4771	TonB-dependent receptor
DLK00_RS04765	COG1629	transport
DLK00_RS04780	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DLK00_RS04785	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DLK00_RS04790	COG0250	Participates in transcription elongation, termination and antitermination
DLK00_RS04795	COG2853	Lipoprotein
DLK00_RS04800	COG0251	oxidation-reduction process
DLK00_RS04810	COG2801	Transposase and inactivated derivatives
DLK00_RS04815	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DLK00_RS04820	COG0456	acetyltransferase
DLK00_RS04840	COG3392	D12 class N6 adenine-specific DNA methyltransferase
DLK00_RS04845	COG4416	COG NOG18757 non supervised orthologous group
DLK00_RS04915	COG4386	tail sheath protein
DLK00_RS04940	COG4397	Mu-like prophage major head subunit gpT
DLK00_RS04945	COG4388	Caudovirus prohead serine protease
DLK00_RS05025	COG3561	AntA/AntB antirepressor
DLK00_RS05105	COG2801	Transposase and inactivated derivatives
DLK00_RS05115	COG2195	Cleaves the N-terminal amino acid of tripeptides
DLK00_RS05120	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
DLK00_RS05140	COG1490	D-aminoacyl-tRNA deacylase activity
DLK00_RS05145	COG0716	FMN binding
DLK00_RS05155	COG1494	fructose-1,6-bisphosphatase
DLK00_RS05165	COG3550	peptidyl-serine autophosphorylation
DLK00_RS05170	COG3550	peptidyl-serine autophosphorylation
DLK00_RS05175	COG1132	(ABC) transporter
DLK00_RS05180	COG4988	ABC transporter
DLK00_RS05185	COG1629	transport
DLK00_RS05185	COG4771	TonB-dependent receptor
DLK00_RS05195	COG2801	Transposase and inactivated derivatives
DLK00_RS05200	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
DLK00_RS05205	COG3620	sequence-specific DNA binding
DLK00_RS05210	COG0488	(ABC) transporter
DLK00_RS05215	COG0551	DNA topoisomerase type I activity
DLK00_RS05240	COG0463	Glycosyl transferase, family 2
DLK00_RS05250	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DLK00_RS05260	COG0210	DNA helicase
DLK00_RS05265	COG2249	NAD(P)H dehydrogenase (quinone) activity
DLK00_RS05270	COG1285	pathogenesis
DLK00_RS05275	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DLK00_RS05280	COG2267	carboxylic ester hydrolase activity
DLK00_RS05300	COG3392	D12 class N6 adenine-specific DNA methyltransferase
DLK00_RS05305	COG4416	COG NOG18757 non supervised orthologous group
DLK00_RS05325	COG3778	Protein conserved in bacteria
DLK00_RS05330	COG3299	homolog of phage Mu protein gp47
DLK00_RS05335	COG4381	Mu-like prophage protein gp46
DLK00_RS05340	COG4384	Bacteriophage Mu Gp45 protein
DLK00_RS05355	COG4228	DNA circulation
DLK00_RS05365	COG4518	Phage tail assembly chaperone proteins, E, or 41 or 14
DLK00_RS05390	COG4387	Mu-like prophage protein GP36
DLK00_RS05400	COG4397	Mu-like prophage major head subunit gpT
DLK00_RS05415	COG5005	Phage virion morphogenesis
DLK00_RS05420	COG2369	cell adhesion
DLK00_RS05425	COG4383	Mu-like prophage protein gp29
DLK00_RS05430	COG4373	Mu-like prophage FluMu protein gp28
DLK00_RS05440	COG0640	Transcriptional regulator
DLK00_RS05480	COG5566	PFAM Mor transcription activator
DLK00_RS05490	COG3561	AntA/AntB antirepressor
DLK00_RS05500	COG4382	Mu-like prophage protein Gp16
DLK00_RS05515	COG4396	Host-nuclease inhibitor protein Gam
DLK00_RS05525	COG2842	Transposition protein
DLK00_RS05530	COG2801	Transposase and inactivated derivatives
DLK00_RS05540	COG2932	Transcriptional regulator
DLK00_RS05590	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DLK00_RS05600	COG0180	Tryptophanyl-tRNA synthetase
DLK00_RS05605	COG3691	Protein conserved in bacteria
DLK00_RS05630	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DLK00_RS05635	COG0038	chloride channel
DLK00_RS05665	COG1072	(Pantothenic acid kinase))
DLK00_RS05675	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
DLK00_RS05680	COG1595	DNA-templated transcription, initiation
DLK00_RS05700	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DLK00_RS05700	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DLK00_RS05740	COG3070	regulator of competence-specific genes
DLK00_RS05760	COG0561	phosphatase activity
DLK00_RS05765	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DLK00_RS05805	COG3069	C4-dicarboxylate transmembrane transporter activity
DLK00_RS05815	COG0737	Belongs to the 5'-nucleotidase family
DLK00_RS05830	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DLK00_RS05850	COG2168	tRNA wobble position uridine thiolation
DLK00_RS05855	COG2923	Belongs to the DsrF TusC family
DLK00_RS05860	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
DLK00_RS05865	COG2964	Protein conserved in bacteria
DLK00_RS05870	COG0545	Peptidyl-prolyl cis-trans isomerase
DLK00_RS05880	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DLK00_RS05880	COG0678	peroxiredoxin activity
DLK00_RS05885	COG0583	DNA-binding transcription factor activity
DLK00_RS05890	COG1309	transcriptional regulator
DLK00_RS05895	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DLK00_RS05900	COG2183	response to ionizing radiation
DLK00_RS05910	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DLK00_RS05915	COG0546	phosphoglycolate phosphatase activity
DLK00_RS05925	COG2801	Transposase and inactivated derivatives
DLK00_RS05935	COG1522	sequence-specific DNA binding
DLK00_RS05940	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DLK00_RS05945	COG1297	OPT oligopeptide transporter protein
DLK00_RS05955	COG1218	3'(2'),5'-bisphosphate nucleotidase
DLK00_RS05960	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DLK00_RS05965	COG0363	glucosamine-6-phosphate deaminase activity
DLK00_RS05970	COG3759	membrane
DLK00_RS05975	COG1943	Transposase
DLK00_RS05980	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DLK00_RS06085	COG1027	Aspartate ammonia-lyase
DLK00_RS06090	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DLK00_RS06105	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DLK00_RS06110	COG1435	thymidine kinase activity
DLK00_RS06120	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DLK00_RS06125	COG3719	Belongs to the RNase T2 family
DLK00_RS06135	COG0191	fructose-bisphosphate aldolase activity
DLK00_RS06145	COG2364	Membrane
DLK00_RS06150	COG1328	CTP reductase activity
DLK00_RS06155	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DLK00_RS06160	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DLK00_RS06195	COG1275	C4-dicarboxylate transporter malic acid transport protein
DLK00_RS06200	COG1720	tRNA m6t6A37 methyltransferase activity
DLK00_RS06205	COG1575	Belongs to the MenA family. Type 1 subfamily
DLK00_RS06220	COG1609	Transcriptional regulator
DLK00_RS06230	COG1879	ABC-type sugar transport system periplasmic component
DLK00_RS06240	COG1129	ABC transporter
DLK00_RS06245	COG1869	D-ribose catabolic process
DLK00_RS06275	COG3700	Belongs to the class B bacterial acid phosphatase family
DLK00_RS06290	COG1238	metal cluster binding
DLK00_RS06335	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DLK00_RS06345	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DLK00_RS06355	COG0814	amino acid
DLK00_RS06365	COG0140	phosphoribosyl-ATP diphosphatase activity
DLK00_RS06365	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DLK00_RS06370	COG0107	imidazoleglycerol-phosphate synthase activity
DLK00_RS06405	COG1561	YicC-like family, N-terminal region
DLK00_RS06410	COG0354	folic acid binding
DLK00_RS06415	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DLK00_RS06420	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DLK00_RS06425	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DLK00_RS06430	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DLK00_RS06435	COG2990	Protein conserved in bacteria
DLK00_RS06440	COG3956	TIGRFAM MazG family protein
DLK00_RS06455	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DLK00_RS06465	COG0470	DNA polymerase III
DLK00_RS06470	COG0084	hydrolase, TatD family'
DLK00_RS06490	COG3309	Virulence-associated protein D
DLK00_RS06500	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DLK00_RS06500	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DLK00_RS06505	COG1105	Belongs to the carbohydrate kinase PfkB family
DLK00_RS06510	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DLK00_RS06510	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
DLK00_RS06510	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DLK00_RS06520	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DLK00_RS06535	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DLK00_RS06545	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DLK00_RS06550	COG4972	Pilus assembly protein
DLK00_RS06555	COG3166	PFAM Fimbrial assembly family protein
DLK00_RS06570	COG4796	Type ii and iii secretion system protein
DLK00_RS06575	COG1040	competence protein
DLK00_RS06590	COG3068	Protein conserved in bacteria
DLK00_RS06595	COG0776	regulation of translation
DLK00_RS06600	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DLK00_RS06625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DLK00_RS06635	COG0513	Belongs to the DEAD box helicase family
DLK00_RS06640	COG0826	peptidase U32
DLK00_RS06645	COG0477	Major facilitator Superfamily
DLK00_RS06655	COG0351	phosphomethylpyrimidine kinase
DLK00_RS06665	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DLK00_RS06670	COG1530	ribonuclease E activity
DLK00_RS06675	COG0564	pseudouridine synthase activity
DLK00_RS06680	COG1923	regulation of RNA biosynthetic process
DLK00_RS06685	COG3283	Transcriptional regulator of aromatic amino acids metabolism
DLK00_RS06695	COG1121	(ABC) transporter
DLK00_RS06700	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DLK00_RS06710	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
DLK00_RS06715	COG0037	tRNA processing
DLK00_RS06725	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DLK00_RS06735	COG3691	Protein conserved in bacteria
DLK00_RS06740	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DLK00_RS06745	COG0494	nUDIX hydrolase
DLK00_RS06755	COG2850	peptidyl-arginine hydroxylation
DLK00_RS06770	COG0012	GTP binding
DLK00_RS06775	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DLK00_RS06780	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
DLK00_RS06785	COG0318	PFAM AMP-dependent synthetase and ligase
DLK00_RS06790	COG3065	identical protein binding
DLK00_RS06795	COG1214	PFAM Peptidase M22, glycoprotease
DLK00_RS06805	COG0824	Thioesterase
DLK00_RS06815	COG0848	biopolymer transport protein
DLK00_RS06820	COG3064	Membrane
DLK00_RS06825	COG0823	Involved in the tonB-independent uptake of proteins
DLK00_RS06830	COG2885	chlorophyll binding
DLK00_RS06840	COG0582	viral genome integration into host DNA
DLK00_RS06850	COG3617	BRO family, N-terminal domain
DLK00_RS06910	COG2189	Belongs to the N(4) N(6)-methyltransferase family
DLK00_RS07055	COG3728	DNA packaging
DLK00_RS07060	COG1783	phage Terminase large subunit
DLK00_RS07185	COG4416	COG NOG18757 non supervised orthologous group
DLK00_RS07190	COG3392	D12 class N6 adenine-specific DNA methyltransferase
DLK00_RS07205	COG1959	2 iron, 2 sulfur cluster binding
DLK00_RS07215	COG0822	iron-sulfur transferase activity
DLK00_RS07220	COG0316	Belongs to the HesB IscA family
DLK00_RS07225	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
DLK00_RS07245	COG2975	iron-sulfur cluster assembly
DLK00_RS07250	COG2976	Protein conserved in bacteria
DLK00_RS07265	COG1426	Protein conserved in bacteria
DLK00_RS07270	COG3063	Type IV pilus biogenesis stability protein PilW
DLK00_RS07280	COG1686	Belongs to the peptidase S11 family
DLK00_RS07300	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DLK00_RS07305	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DLK00_RS07310	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DLK00_RS07315	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DLK00_RS07320	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DLK00_RS07325	COG1116	anion transmembrane transporter activity
DLK00_RS07335	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DLK00_RS07355	COG3043	anaerobic respiration
DLK00_RS07360	COG0348	domain, Protein
DLK00_RS07375	COG3062	negative regulation of establishment of protein localization
DLK00_RS07380	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DLK00_RS07385	COG3171	Protein conserved in bacteria
DLK00_RS07390	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DLK00_RS07405	COG0347	Belongs to the P(II) protein family
DLK00_RS07410	COG0521	Mo-molybdopterin cofactor biosynthetic process
DLK00_RS07415	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DLK00_RS07420	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DLK00_RS07430	COG1381	Involved in DNA repair and RecF pathway recombination
DLK00_RS07440	COG3061	Opacity-associated protein A
DLK00_RS07440	COG3266	domain, Protein
DLK00_RS07445	COG1509	lysine 2,3-aminomutase activity
DLK00_RS07465	COG2056	Na+-H+ antiporter family
DLK00_RS07470	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DLK00_RS07475	COG0346	lactoylglutathione lyase activity
DLK00_RS07495	COG1755	Isoprenylcysteine carboxyl methyltransferase
DLK00_RS07505	COG0494	nUDIX hydrolase
DLK00_RS07565	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DLK00_RS07575	COG4535	Mg2 and Co2 transporter CorC
DLK00_RS07580	COG3023	N-Acetylmuramoyl-L-alanine amidase
DLK00_RS07585	COG4969	Belongs to the N-Me-Phe pilin family
DLK00_RS07590	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DLK00_RS07600	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DLK00_RS07605	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DLK00_RS07615	COG0789	Transcriptional regulator
DLK00_RS07620	COG2608	mercury ion transmembrane transporter activity
DLK00_RS07625	COG2608	mercury ion transmembrane transporter activity
DLK00_RS07630	COG2608	mercury ion transmembrane transporter activity
DLK00_RS07635	COG2608	mercury ion transmembrane transporter activity
DLK00_RS07640	COG2608	mercury ion transmembrane transporter activity
DLK00_RS07650	COG0814	amino acid
DLK00_RS07660	COG0814	amino acid
DLK00_RS07665	COG0436	Aminotransferase
DLK00_RS07675	COG1169	isochorismate synthase
DLK00_RS07685	COG2267	carboxylic ester hydrolase activity
DLK00_RS07690	COG0477	Major facilitator Superfamily
DLK00_RS07695	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
DLK00_RS07700	COG2258	MOSC domain
DLK00_RS07715	COG1368	sulfuric ester hydrolase activity
DLK00_RS07750	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DLK00_RS07760	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
DLK00_RS07765	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DLK00_RS07770	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DLK00_RS07785	COG3850	Histidine kinase
DLK00_RS07795	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DLK00_RS07815	COG0859	PFAM glycosyl transferase family 9
DLK00_RS07825	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DLK00_RS07840	COG0582	viral genome integration into host DNA
DLK00_RS07850	COG3311	Transcriptional regulator
DLK00_RS07915	COG2026	Addiction module toxin, RelE StbE family
DLK00_RS07925	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DLK00_RS07930	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
DLK00_RS07940	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DLK00_RS07945	COG0811	peptide transport
DLK00_RS07950	COG0848	biopolymer transport protein
DLK00_RS07955	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
DLK00_RS07960	COG0629	single-stranded DNA binding
DLK00_RS07975	COG0641	radical SAM
DLK00_RS07990	COG3945	hemerythrin HHE cation binding domain
DLK00_RS07995	COG0425	Belongs to the sulfur carrier protein TusA family
DLK00_RS08000	COG1862	Preprotein translocase
DLK00_RS08010	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DLK00_RS08020	COG1393	Belongs to the ArsC family
DLK00_RS08025	COG3036	rescue of stalled ribosome
DLK00_RS08040	COG0513	Belongs to the DEAD box helicase family
DLK00_RS08045	COG4785	May be involved in cell division
DLK00_RS08060	COG2731	YhcH YjgK YiaL family protein
DLK00_RS08065	COG1114	Component of the transport system for branched-chain amino acids
DLK00_RS08075	COG1522	sequence-specific DNA binding
DLK00_RS08080	COG2962	Rard protein
DLK00_RS08090	COG0517	IMP dehydrogenase activity
DLK00_RS08090	COG0516	GMP reductase activity
DLK00_RS08095	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
DLK00_RS08095	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
DLK00_RS08120	COG1573	uracil-dna glycosylase
DLK00_RS08130	COG3059	membrane
DLK00_RS08140	COG0339	signal peptide processing
DLK00_RS08145	COG2832	Protein of unknown function (DUF454)
DLK00_RS08150	COG4166	transmembrane transport
DLK00_RS08160	COG0671	phosphoesterase, PA-phosphatase related
DLK00_RS08170	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DLK00_RS08180	COG0737	Belongs to the 5'-nucleotidase family
DLK00_RS08215	COG1560	Kdo2-lipid A biosynthetic process
DLK00_RS08220	COG0730	response to heat
DLK00_RS08245	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
DLK00_RS08255	COG0716	FMN binding
DLK00_RS08260	COG0735	belongs to the Fur family
DLK00_RS08265	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DLK00_RS08270	COG0805	protein transport
DLK00_RS08285	COG0789	Transcriptional regulator
DLK00_RS08290	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
DLK00_RS08295	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
DLK00_RS08315	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
DLK00_RS08340	COG2991	Protein conserved in bacteria
DLK00_RS08355	COG0564	pseudouridine synthase activity
DLK00_RS08360	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DLK00_RS08370	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DLK00_RS08375	COG1882	Formate acetyltransferase
DLK00_RS08390	COG1115	amino acid carrier protein
DLK00_RS08395	COG0271	Belongs to the BolA IbaG family
DLK00_RS08400	COG2801	Transposase and inactivated derivatives
DLK00_RS08410	COG3056	Lipoprotein
DLK00_RS08415	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DLK00_RS08420	COG0688	phosphatidylethanolamine metabolic process
DLK00_RS08425	COG1399	metal-binding, possibly nucleic acid-binding protein
DLK00_RS08450	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DLK00_RS08455	COG1028	Short-chain dehydrogenase reductase Sdr
DLK00_RS08465	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
DLK00_RS08470	COG2091	lysine biosynthetic process via aminoadipic acid
DLK00_RS08475	COG0330	HflC and HflK could
DLK00_RS08480	COG0330	HflC and HflK could
DLK00_RS08485	COG2020	methyltransferase activity
DLK00_RS08500	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DLK00_RS08505	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
DLK00_RS08520	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DLK00_RS08530	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DLK00_RS08560	COG1160	GTP binding
DLK00_RS08565	COG2814	Major facilitator Superfamily
DLK00_RS08585	COG2252	PERMEase
DLK00_RS08590	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DLK00_RS08610	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DLK00_RS08620	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DLK00_RS08625	COG5413	integral membrane protein
DLK00_RS08630	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
DLK00_RS08635	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DLK00_RS08720	COG2959	enzyme of heme biosynthesis
DLK00_RS08735	COG1045	serine acetyltransferase
DLK00_RS08745	COG0471	metal ion transport
DLK00_RS08765	COG0738	Major facilitator superfamily
DLK00_RS08770	COG0235	Class ii aldolase
DLK00_RS08780	COG1070	Carbohydrate kinase
DLK00_RS08790	COG1349	DNA-binding transcription factor activity
DLK00_RS08800	COG0564	pseudouridine synthase activity
DLK00_RS08805	COG0705	Rhomboid family
DLK00_RS08810	COG1349	DNA-binding transcription factor activity
DLK00_RS08815	COG1464	Belongs to the NlpA lipoprotein family
DLK00_RS08830	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DLK00_RS08865	COG0625	glutathione transferase activity
DLK00_RS08870	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DLK00_RS08880	COG3610	response to peptide
DLK00_RS08885	COG4536	flavin adenine dinucleotide binding
DLK00_RS08890	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DLK00_RS08910	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DLK00_RS08915	COG0326	Molecular chaperone. Has ATPase activity
DLK00_RS08925	COG1393	Belongs to the ArsC family
DLK00_RS08935	COG1876	peptidase activity
DLK00_RS08945	COG1178	ABC-type Fe3 transport system permease component
DLK00_RS08950	COG1840	ABC-type Fe3 transport system, periplasmic component
DLK00_RS08955	COG4797	methyltransferase
DLK00_RS08955	COG4797	methyltransferase
DLK00_RS08960	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DLK00_RS08965	COG0460	homoserine dehydrogenase
DLK00_RS08965	COG0527	aspartate kinase activity
DLK00_RS09000	COG0626	cystathionine gamma-synthase activity
DLK00_RS09010	COG3118	belongs to the thioredoxin family
DLK00_RS09020	COG0084	hydrolase, TatD family'
DLK00_RS09035	COG2833	Protein of unknown function (DUF455)
DLK00_RS09040	COG1946	Acyl-CoA thioesterase
DLK00_RS09045	COG1328	CTP reductase activity
DLK00_RS09045	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DLK00_RS09055	COG1741	Belongs to the pirin family
DLK00_RS09085	COG3392	D12 class N6 adenine-specific DNA methyltransferase
DLK00_RS09090	COG4416	COG NOG18757 non supervised orthologous group
DLK00_RS09275	COG4382	Mu-like prophage protein Gp16
DLK00_RS09295	COG4396	Host-nuclease inhibitor protein Gam
DLK00_RS09310	COG2801	Transposase and inactivated derivatives
DLK00_RS09315	COG3423	Transcriptional regulator
DLK00_RS09330	COG3059	membrane
DLK00_RS09335	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DLK00_RS09345	COG0497	DNA recombination
DLK00_RS09355	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DLK00_RS09365	COG0860	N-Acetylmuramoyl-L-alanine amidase
DLK00_RS09365	COG1388	LysM domain
DLK00_RS09370	COG0802	atpase or kinase
DLK00_RS09375	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DLK00_RS09380	COG0617	tRNA 3'-terminal CCA addition
DLK00_RS09385	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DLK00_RS09390	COG2333	competence protein COMEC
DLK00_RS09390	COG0658	competence protein
DLK00_RS09425	COG2186	Transcriptional regulator
DLK00_RS09440	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
DLK00_RS09465	COG0800	Aldolase
DLK00_RS09470	COG2824	Alkylphosphonate utilization operon protein PhnA
DLK00_RS09475	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
DLK00_RS09485	COG0670	Belongs to the BI1 family
DLK00_RS09510	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
DLK00_RS09515	COG1792	Involved in formation and maintenance of cell shape
DLK00_RS09520	COG1077	Cell shape determining protein MreB Mrl
DLK00_RS09535	COG0799	negative regulation of ribosome biogenesis
DLK00_RS09545	COG0768	penicillin binding
DLK00_RS09550	COG0772	Belongs to the SEDS family
DLK00_RS09555	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DLK00_RS09555	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DLK00_RS09560	COG1686	Belongs to the peptidase S11 family
DLK00_RS09575	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DLK00_RS09580	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
DLK00_RS09590	COG2301	Belongs to the HpcH HpaI aldolase family
DLK00_RS09600	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
DLK00_RS09600	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
DLK00_RS09605	COG0471	metal ion transport
DLK00_RS09615	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DLK00_RS09625	COG0481	GTPase activity
DLK00_RS09645	COG2813	Specifically methylates the guanine in position
DLK00_RS09650	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
DLK00_RS09655	COG0456	acetyltransferase
DLK00_RS09670	COG0437	4 iron, 4 sulfur cluster binding
DLK00_RS09685	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DLK00_RS09690	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DLK00_RS09695	COG0561	phosphatase activity
DLK00_RS09705	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DLK00_RS09710	COG0194	GDP metabolic process
DLK00_RS09720	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DLK00_RS09780	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DLK00_RS09785	COG1687	branched-chain amino acid
DLK00_RS09800	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DLK00_RS09850	COG3112	Uncharacterised protein family (UPF0231)
DLK00_RS09860	COG0024	Methionine aminopeptidase
DLK00_RS09890	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DLK00_RS09895	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DLK00_RS09900	COG2190	(PTS) system
DLK00_RS09910	COG3111	PFAM Bacterial OB fold (BOF) protein
DLK00_RS09915	COG0745	RESPONSE REGULATOR receiver
DLK00_RS09925	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DLK00_RS09935	COG0795	lipopolysaccharide-transporting ATPase activity
DLK00_RS09950	COG1434	Gram-negative-bacterium-type cell wall biogenesis
DLK00_RS09970	COG3306	glycosyltransferase involved in LPS biosynthesis
DLK00_RS09980	COG1216	Glycosyl transferase, family 2
DLK00_RS09985	COG2005	Transcriptional regulator
DLK00_RS09990	COG0725	ABC transporter, periplasmic molybdate-binding protein
DLK00_RS10000	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
DLK00_RS10010	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DLK00_RS10015	COG4660	Part of a membrane complex involved in electron transport
DLK00_RS10045	COG0616	signal peptide processing
DLK00_RS10055	COG1289	transmembrane transporter activity
DLK00_RS10075	COG3025	triphosphatase activity
DLK00_RS10080	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DLK00_RS10085	COG1522	sequence-specific DNA binding
DLK00_RS10110	COG0788	formyltetrahydrofolate deformylase activity
DLK00_RS10115	COG2916	Histone family protein nucleoid-structuring protein H-NS
DLK00_RS10135	COG0440	acetolactate synthase activity
DLK00_RS10150	COG3102	Protein conserved in bacteria
DLK00_RS10160	COG3133	Outer membrane lipoprotein
DLK00_RS10165	COG1216	Glycosyl transferase, family 2
DLK00_RS10180	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DLK00_RS10185	COG0305	Participates in initiation and elongation during chromosome replication
DLK00_RS10190	COG0469	pyruvate kinase activity
DLK00_RS10210	COG4383	Mu-like prophage protein gp29
DLK00_RS10215	COG2369	cell adhesion
DLK00_RS10220	COG5005	Phage virion morphogenesis
DLK00_RS10240	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DLK00_RS10245	COG3101	peptidyl-lysine hydroxylation
DLK00_RS10250	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DLK00_RS10260	COG2890	protein-(glutamine-N5) methyltransferase activity
DLK00_RS10265	COG2912	Transglutaminase-like superfamily
DLK00_RS10275	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DLK00_RS10280	COG4591	ABC-type transport system involved in lipoprotein release permease component
DLK00_RS10285	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DLK00_RS10295	COG2830	Protein of unknown function (DUF452)
DLK00_RS10300	COG0500	methyltransferase
DLK00_RS10305	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DLK00_RS10310	COG1136	(ABC) transporter
DLK00_RS10325	COG2932	Transcriptional regulator
DLK00_RS10335	COG2249	NAD(P)H dehydrogenase (quinone) activity
DLK00_RS10340	COG3381	protein complex oligomerization
DLK00_RS10345	COG0778	Nitroreductase
DLK00_RS10355	COG3475	LICD family
DLK00_RS10360	COG4750	Nucleotidyl transferase
DLK00_RS10380	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DLK00_RS10385	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DLK00_RS10395	COG0786	glutamate:sodium symporter activity
DLK00_RS10405	COG0187	DNA topoisomerase II activity
DLK00_RS10410	COG1560	Kdo2-lipid A biosynthetic process
DLK00_RS10415	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DLK00_RS10415	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DLK00_RS10435	COG0488	(ABC) transporter
DLK00_RS10440	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DLK00_RS10445	COG1177	transmembrane transport
DLK00_RS10450	COG1176	ABC-type spermidine putrescine transport system, permease component I
DLK00_RS10465	COG0783	Belongs to the Dps family
DLK00_RS10495	COG2983	Belongs to the UPF0260 family
DLK00_RS10515	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DLK00_RS10520	COG0297	glycogen (starch) synthase activity
DLK00_RS10525	COG0058	SHG alpha-glucan phosphorylase activity
DLK00_RS10530	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
DLK00_RS10535	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
DLK00_RS10540	COG0583	DNA-binding transcription factor activity
DLK00_RS10545	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DLK00_RS10555	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)