locus_tag old_locus_tag gene Name start end strand product note type ID NCBI HI0001 HI0001 gapdH gapdH 2 1021 + glyceraldehyde-3-phosphate dehydrogenase catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate gene gene0 http://www.ncbi.nlm.nih.gov/gene/?term=HI0001 HI0002 HI0002 HI0002 1190 3013 + long chain fatty acid CoA ligase similar to GB:AE000782 gene gene1 http://www.ncbi.nlm.nih.gov/gene/?term=HI0002 HI0003 HI0003 HI0003 3050 3838 - haloacid dehalogenase-like protein similar to GB:L10328 SP:P09997 PID:290545 PID:41648 GB:U00096 gene gene2 http://www.ncbi.nlm.nih.gov/gene/?term=HI0003 HI0004 HI0004 HI0004 3854 4318 - metalloprotease similar to GB:U00096 SP:P77385 PID:1778578 PID:1786880 gene gene3 http://www.ncbi.nlm.nih.gov/gene/?term=HI0004 HI0005 HI0005 fdhD fdhD 4579 5391 - formate dehydrogenase accessory protein involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth gene gene4 http://www.ncbi.nlm.nih.gov/gene/?term=HI0005 HI0006m HI0006m fdnG fdnG 5662 8748 + gene gene5 http://www.ncbi.nlm.nih.gov/gene/?term=HI0006m HI0007 HI0007 fdxH fdxH 8750 9688 + formate dehydrogenase subunit beta similar to SP:P24184 GB:U00096 PID:1742408 PID:1742418 PID:1787749 gene gene6 http://www.ncbi.nlm.nih.gov/gene/?term=HI0007 HI0008 HI0008 fdxI fdxI 9681 10397 + formate dehydrogenase subunit gamma similar to GB:L19201 SP:P32174 PID:304996 GB:U00096 PID:1790325 gene gene7 http://www.ncbi.nlm.nih.gov/gene/?term=HI0008 HI0009 HI0009 fdhE fdhE 10467 11375 + formate dehydrogenase accessory protein FdhE required for the formation of active formate dehydrogenase gene gene8 http://www.ncbi.nlm.nih.gov/gene/?term=HI0009 HI0010 HI0010 rimI rimI 11414 11854 - ribosomal-protein-alanine N-acetyltransferase alanine acetyltransferase that specifically acetylates ribosomal protein S18 gene gene9 http://www.ncbi.nlm.nih.gov/gene/?term=HI0010 HI0011 HI0011 holD holD 11857 12261 - DNA polymerase III subunit psi with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB gene gene10 http://www.ncbi.nlm.nih.gov/gene/?term=HI0011 HI0012 HI0012 rsmC rsmC 12367 13359 + 16S rRNA methyltransferase 16S rRNA M2G1207 methyltransferase%3B one of many enzymes that modify bases of the ribosomal RNA%3B this enzyme methylates the G at position 1207 of the small ribosomal subunit gene gene11 http://www.ncbi.nlm.nih.gov/gene/?term=HI0012 HI0013 HI0013 era era 13423 14331 - GTP-binding protein Era Era%3B Escherichia coli Ras-like protein%3B Bex%3B Bacillus Era-complementing segment%3B essential protein in Escherichia coli that is involved in many cellular processes%3B GTPase%3B binds the cell membrane through apparent C-terminal domain%3B mutants are arrested during the cell cycle%3B Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome gene gene12 http://www.ncbi.nlm.nih.gov/gene/?term=HI0013 HI0014 HI0014 rnc rnc 14328 15011 - ribonuclease III cytoplasmic enzyme involved in processing rRNA and some mRNAs%3B substrates typically have dsRNA regions%3B forms a homodimer%3B have N-terminal nuclease and C-terminal RNA-binding domains%3B requires magnesium as preferred ion for activity gene gene13 http://www.ncbi.nlm.nih.gov/gene/?term=HI0014 HI0015 HI0015 lepB lepB 15013 16062 - signal peptidase I similar to GB:K00426 SP:P00803 PID:146600 PID:987643 GB:U00096 gene gene14 http://www.ncbi.nlm.nih.gov/gene/?term=HI0015 HI0016 HI0016 lepA lepA 16071 17867 - GTP-binding protein LepA binds to the ribosome on the universally-conserved alpha-sarcin loop gene gene15 http://www.ncbi.nlm.nih.gov/gene/?term=HI0016 HI0017 HI0017 HI0017 18035 18418 - autonomous glycyl radical cofactor GrcA stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit gene gene16 http://www.ncbi.nlm.nih.gov/gene/?term=HI0017 HI0018 HI0018 ung ung 18676 19335 + uracil-DNA glycosylase Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine gene gene17 http://www.ncbi.nlm.nih.gov/gene/?term=HI0018 HI0019 HI0019 HI0019 19405 20829 - (dimethylallyl)adenosine tRNA methylthiotransferase catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) gene gene18 http://www.ncbi.nlm.nih.gov/gene/?term=HI0019 HI0020 HI0020 HI0020 21248 22687 - hypothetical protein similar to GB:U00096 SP:P75763 PID:1786986 gene gene19 http://www.ncbi.nlm.nih.gov/gene/?term=HI0020 HI0021 HI0021 citG citG 22689 23939 - CitG protein similar to GB:U00096 SP:P77231 PID:1778530 PID:1786830 gene gene20 http://www.ncbi.nlm.nih.gov/gene/?term=HI0021 HI0022 HI0022 citF citF 24267 25769 - citrate lyase subunit alpha similar to GB:U00096 SP:P75726 PID:1778532 PID:1786832 gene gene21 http://www.ncbi.nlm.nih.gov/gene/?term=HI0022 HI0023 HI0023 citE citE 25784 26641 - citrate lyase subunit beta similar to GB:U00096 SP:P77770 PID:1778533 PID:1786833 gene gene22 http://www.ncbi.nlm.nih.gov/gene/?term=HI0023 HI0024 HI0024 citD citD 26656 26943 - citrate lyase subunit gamma acyl carrier protein%3B with CitE and CitF catalyzes the formation of oxaloacetate from citrate gene gene23 http://www.ncbi.nlm.nih.gov/gene/?term=HI0024 HI0025 HI0025 citC citC 26981 27988 - [citrate (pro-3S)-lyase] ligase similar to SP:P77390 gene gene24 http://www.ncbi.nlm.nih.gov/gene/?term=HI0025 HI0026 HI0026 lipA lipA 28239 29201 - lipoyl synthase catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group gene gene25 http://www.ncbi.nlm.nih.gov/gene/?term=HI0026 HI0027 HI0027 lipB lipB 29255 29893 - lipoate-protein ligase B lipoyl/octanoyltransferase%3B catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein gene gene26 http://www.ncbi.nlm.nih.gov/gene/?term=HI0027 HI0028 HI0028 HI0028 29895 30173 - hypothetical protein similar to GB:L07636 SP:P30977 PID:146621 GB:U00096 PID:1778548 gene gene27 http://www.ncbi.nlm.nih.gov/gene/?term=HI0028 HI0029 HI0029 dacA dacA 30229 31410 - penicillin-binding protein 5 similar to SP:P04287 PID:146620 PID:147661 PID:41212 GB:U00096 gene gene28 http://www.ncbi.nlm.nih.gov/gene/?term=HI0029 HI0030 HI0030 HI0030 31426 32289 - lipoprotein similar to GB:M18276 SP:P10100 PID:147660 GB:U00096 PID:1651260 gene gene29 http://www.ncbi.nlm.nih.gov/gene/?term=HI0030 HI0031 HI0031 rodA rodA 32341 33456 - rod shape-determining protein similar to GB:M22857 SP:P15035 PID:147695 GB:U00096 PID:1651261 gene gene30 http://www.ncbi.nlm.nih.gov/gene/?term=HI0031 HI0032 HI0032 pbp2 pbp2 33446 35401 - penicillin-binding protein 2 similar to SP:P08150 GB:X04516 PID:147694 PID:42316 GB:U00096 gene gene31 http://www.ncbi.nlm.nih.gov/gene/?term=HI0032 HI0033 HI0033 HI0033 35422 35889 - 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH SPOUT methyltransferase family protein%3B crystal structure shows homodimer%3B in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA gene gene32 http://www.ncbi.nlm.nih.gov/gene/?term=HI0033 HI0034 HI0034 HI0034 35943 36251 - hypothetical protein similar to SP:P05848 GB:X04516 PID:42314 GB:U00096 PID:1778554 gene gene33 http://www.ncbi.nlm.nih.gov/gene/?term=HI0034 HI0035 HI0035 HI0035 36376 38031 - hypothetical protein similar to GB:L10328 SP:P29211 GB:M94104 PID:290534 PID:147371 gene gene34 http://www.ncbi.nlm.nih.gov/gene/?term=HI0035 HI0036 HI0036 HI0036 38237 40015 + ABC transporter ATP-binding protein similar to SP:Q50614 PID:1483552 gene gene35 http://www.ncbi.nlm.nih.gov/gene/?term=HI0036 HI0037 HI0037 mreB mreB 40145 41200 + rod shape-determining protein MreB functions in MreBCD complex in some organisms gene gene36 http://www.ncbi.nlm.nih.gov/gene/?term=HI0037 HI0038 HI0038 mreC mreC 41280 42335 + rod shape-determining protein MreC in some organisms this protein is a transmembrane protein while in others it is periplasmic%3B involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall gene gene37 http://www.ncbi.nlm.nih.gov/gene/?term=HI0038 HI0039 HI0039 mreD mreD 42335 42823 + rod shape-determining protein MreD similar to GB:M31792 SP:P16927 PID:146819 PID:606189 GB:U00096 gene gene38 http://www.ncbi.nlm.nih.gov/gene/?term=HI0039 HI0040 HI0040 HI0040 42874 43650 - hypothetical protein similar to PID:1944176 gene gene39 http://www.ncbi.nlm.nih.gov/gene/?term=HI0040 HI0041 HI0041 xthA xthA 43660 44463 - exonuclease III removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction gene gene40 http://www.ncbi.nlm.nih.gov/gene/?term=HI0041 HI0042 HI0042 HI0042 44511 45185 - pseudouridine synthase-like protein similar to SP:P39219 GB:U00096 PID:1786244 gene gene41 http://www.ncbi.nlm.nih.gov/gene/?term=HI0042 HI0043 HI0043 HI0043 45185 46249 - hypothetical protein similar to SP:P45525 GB:U00096 PID:1787582 gene gene42 http://www.ncbi.nlm.nih.gov/gene/?term=HI0043 HI0044 HI0044 HI0044 46309 46971 - hypothetical protein similar to SP:P06967 GB:X00547 PID:41284 GB:U00096 PID:1787205 gene gene43 http://www.ncbi.nlm.nih.gov/gene/?term=HI0044 HI0045 HI0045 HI0045 47298 47852 - hypothetical protein similar to GB:U14003 SP:P39187 PID:471102 PID:537057 GB:U00096 gene gene45 http://www.ncbi.nlm.nih.gov/gene/?term=HI0045 HI0046 HI0046 phnA phnA 47955 48281 + alkylphosphonate uptake protein similar to SP:P16680 GB:U14003 PID:147194 PID:536952 GB:U00096 gene gene46 http://www.ncbi.nlm.nih.gov/gene/?term=HI0046 HI0047 HI0047 eda eda 48334 48972 - keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate%3B or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate gene gene47 http://www.ncbi.nlm.nih.gov/gene/?term=HI0047 HI0048 HI0048 HI0048 48991 49848 - D-mannonate oxidoreductase Converts D-mannonate to D-mannuronate gene gene48 http://www.ncbi.nlm.nih.gov/gene/?term=HI0048 HI0049 HI0049 kdgK kdgK 49848 50792 - 2-dehydro-3-deoxygluconokinase similar to GB:X75047 SP:P45416 PID:495249 gene gene49 http://www.ncbi.nlm.nih.gov/gene/?term=HI0049 HI0050m HI0050m HI0050m 50812 52086 - integral membrane protein transporter gene gene50 http://www.ncbi.nlm.nih.gov/gene/?term=HI0050m HI0051 HI0051 HI0051 52092 52589 - hypothetical protein similar to SP:P37674 PID:466715 GB:U00096 PID:1790002 gene gene51 http://www.ncbi.nlm.nih.gov/gene/?term=HI0051 HI0052 HI0052 HI0052 52628 53614 - hypothetical protein similar to SP:P37676 PID:466717 GB:U00096 PID:1790004 gene gene52 http://www.ncbi.nlm.nih.gov/gene/?term=HI0052 HI0053 HI0053 HI0053 53641 54669 - zinc-type alcohol dehydrogenase similar to GB:M96947 SP:Q06004 PID:304153 GB:AL009126 gene gene53 http://www.ncbi.nlm.nih.gov/gene/?term=HI0053 HI0054 HI0054 uxuR uxuR 54830 55579 + uxu operon regulator similar to GB:U14003 SP:P39161 PID:537165 PID:1160324 GB:U00096 gene gene54 http://www.ncbi.nlm.nih.gov/gene/?term=HI0054 HI0055 HI0055 uxuA uxuA 55607 56791 + mannonate dehydratase catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate gene gene55 http://www.ncbi.nlm.nih.gov/gene/?term=HI0055 HI0056 HI0056 HI0056 56844 57557 - hypothetical protein similar to PID:882725 GB:U00096 PID:1789197 gene gene56 http://www.ncbi.nlm.nih.gov/gene/?term=HI0056 HI0057 HI0057 uvrC uvrC 57655 59484 - excinuclease ABC subunit C The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision gene gene57 http://www.ncbi.nlm.nih.gov/gene/?term=HI0057 HI0058 HI0058 kdsB kdsB 59486 60250 - 3-deoxy-manno-octulosonate cytidylyltransferase CMP-2-keto-3-deoxyoctulosonic acid synthetase%3B catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS gene gene58 http://www.ncbi.nlm.nih.gov/gene/?term=HI0058 HI0059 HI0059 lpxK lpxK 60321 61319 - tetraacyldisaccharide 4'-kinase transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1%2C4'-bis-phosphate gene gene59 http://www.ncbi.nlm.nih.gov/gene/?term=HI0059 HI0060 HI0060 msbA msbA 61392 63155 - lipid transporter ATP-binding/permease involved in the transport of lipid A across the inner membrane gene gene60 http://www.ncbi.nlm.nih.gov/gene/?term=HI0060 HI0061 HI0061 rec2 rec2 63196 65562 - recombination protein similar to GB:L20805 PID:305386 gene gene61 http://www.ncbi.nlm.nih.gov/gene/?term=HI0061 HI0062 HI0062 dksA dksA 65821 66258 + dnaK suppressor protein similar to GB:D26562 SP:P18274 GB:M34945 GB:M60726 PID:145751 gene gene62 http://www.ncbi.nlm.nih.gov/gene/?term=HI0062 HI0063 HI0063 pcnB pcnB 66506 67864 + polyA polymerase similar to SP:P13685 GB:D26562 GB:M20574 GB:S48039 PID:147117 gene gene63 http://www.ncbi.nlm.nih.gov/gene/?term=HI0063 HI0064 HI0064 folK folK 67873 68355 + 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase ATP-binding protein%3B similar to GB:D26562 SP:P26281 GB:L06495 PID:146013 PID:473801 gene gene64 http://www.ncbi.nlm.nih.gov/gene/?term=HI0064 HI0065 HI0065 yjeE yjeE 68431 68907 + hypothetical protein forms homotrimers%3B magnesium-dependent%3B similar to SP:P31805 PID:304913 PID:537009 GB:U00096 PID:1790610 gene gene65 http://www.ncbi.nlm.nih.gov/gene/?term=HI0065 HI0066 HI0066 HI0066 68915 70213 + N-acetylmuramoyl-L-alanine amidase similar to SP:P26365 GB:Z11831 PID:304914 PID:42068 PID:537010 gene gene66 http://www.ncbi.nlm.nih.gov/gene/?term=HI0066 HI0067 HI0067 mutL mutL 70214 72103 + DNA mismatch repair protein This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex gene gene67 http://www.ncbi.nlm.nih.gov/gene/?term=HI0067 HI0068 HI0068 miaA miaA 72111 73046 + tRNA delta(2)-isopentenylpyrophosphate transferase IPP transferase%3B isopentenyltransferase%3B involved in tRNA modification%3B in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil%3B further tRNA modifications may occur%3B mutations in miaA result in defects in translation efficiency and fidelity gene gene68 http://www.ncbi.nlm.nih.gov/gene/?term=HI0068 HI0069 HI0069 glnE glnE 73052 75997 + [glutamate--ammonia-ligase] adenylyltransferase catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase%3B also catalyzes the reverse reaction - deadenylation%3B adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme gene gene69 http://www.ncbi.nlm.nih.gov/gene/?term=HI0069 HI0070 HI0070 recN recN 76082 77758 - DNA repair protein similar to SP:P05824 GB:Y00357 PID:42693 PID:1033112 GB:U00096 gene gene70 http://www.ncbi.nlm.nih.gov/gene/?term=HI0070 HI0071 HI0071 grpE grpE 78763 79455 + heat shock protein GrpE with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins%3B may act as a thermosensor gene gene72 http://www.ncbi.nlm.nih.gov/gene/?term=HI0071 HI0072 HI0072 ppnK ppnK 77902 78687 - inorganic polyphosphate/ATP-NAD kinase catalyzes the phosphorylation of NAD to NADP gene gene71 http://www.ncbi.nlm.nih.gov/gene/?term=HI0072 HI0073 HI0073 HI0073 79468 79812 - nucleotidyltransferase forms complexes with HI0074 gene gene73 http://www.ncbi.nlm.nih.gov/gene/?term=HI0073 HI0074 HI0074 HI0074 79805 80245 - nucleotidyltransferase forms homodimers and complexes with HI0073 gene gene74 http://www.ncbi.nlm.nih.gov/gene/?term=HI0074 HI0075 HI0075 nrdD nrdD 80526 82649 + anaerobic ribonucleoside triphosphate reductase Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates gene gene75 http://www.ncbi.nlm.nih.gov/gene/?term=HI0075 HI0076 HI0076 tesB tesB 82767 83627 + acyl-CoA thioesterase II similar to GB:M63308 SP:P23911 PID:147932 GB:U00096 PID:1773136 gene gene76 http://www.ncbi.nlm.nih.gov/gene/?term=HI0076 HI0077 HI0077 HI0077 83638 84504 + hypothetical protein gene gene77 http://www.ncbi.nlm.nih.gov/gene/?term=HI0077 HI0078 HI0078 cysS cysS 84580 85959 - cysteine--tRNA ligase catalyzes a two-step reaction%3B charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA gene gene78 http://www.ncbi.nlm.nih.gov/gene/?term=HI0078 HI0079 HI0079 ppiB ppiB 86062 86571 + peptidyl-prolyl cis-trans isomerase B similar to GB:M55430 SP:P23869 GB:X59293 PID:145290 PID:41205 gene gene79 http://www.ncbi.nlm.nih.gov/gene/?term=HI0079 HI0080 HI0080 HI0080 86575 87006 + hypothetical protein similar to GB:U00096 PID:2367279 gene gene80 http://www.ncbi.nlm.nih.gov/gene/?term=HI0080 HI0081 HI0081 HI0081 87148 87936 + hypothetical protein similar to GB:U14003 SP:P39408 PID:537218 GB:U00096 PID:1790838 gene gene81 http://www.ncbi.nlm.nih.gov/gene/?term=HI0081 HI0082 HI0082 HI0082 88193 88459 + hypothetical protein gene gene82 http://www.ncbi.nlm.nih.gov/gene/?term=HI0082 HI0083 HI0083 HI0083 88435 88742 + gene gene83 http://www.ncbi.nlm.nih.gov/gene/?term=HI0083 HI0084 HI0084 trxM trxM 88739 89062 - thioredoxin similar to GB:J04475 SP:P12243 PID:142154 gene gene84 http://www.ncbi.nlm.nih.gov/gene/?term=HI0084 HI0085 HI0085 ldhA ldhA 89182 90177 - D-lactate dehydrogenase Catalyzes the reduction of sulfopyruvate to (R)-sulfolactate much more efficiently than the reverse reaction. Also catalyzes the reduction of oxaloacetate%2C alpha-ketoglutarate%2C and to a much lower extent%2C KHTCA%2C but not pyruvate. Involved in the biosynthes gene gene85 http://www.ncbi.nlm.nih.gov/gene/?term=HI0085 HI0086 HI0086 metB metB 90190 91335 - cystathionine gamma-synthase catalyzes the formation of cysteine from cystathionine%3B in B. subtilis also has O-acetylhomoserine thiolyase activity gene gene86 http://www.ncbi.nlm.nih.gov/gene/?term=HI0086 HI0086.1 HI0086.1 tRNA-Cys-1 tRNA-Cys-1 91628 91701 + tRNA-Cys tRNA gene88 http://www.ncbi.nlm.nih.gov/gene/?term=HI0086.1 HI0086.2 HI0086.2 HI0086.2 91546 91621 + tRNA-Gly tRNA gene87 http://www.ncbi.nlm.nih.gov/gene/?term=HI0086.2 HI0086.3 HI0086.3 HI0086.3 91729 91815 + tRNA-Leu tRNA gene89 http://www.ncbi.nlm.nih.gov/gene/?term=HI0086.3 HI0086.4 HI0086.4 HI0086.4 91866 91941 + tRNA-Lys tRNA gene90 http://www.ncbi.nlm.nih.gov/gene/?term=HI0086.4 HI0087 HI0087 thrC thrC 92148 93425 - threonine synthase catalyzes the formation of L-threonine from O-phospho-L-homoserine gene gene91 http://www.ncbi.nlm.nih.gov/gene/?term=HI0087 HI0088 HI0088 thrB thrB 93468 94412 - homoserine kinase catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate gene gene92 http://www.ncbi.nlm.nih.gov/gene/?term=HI0088 HI0089 HI0089 thrA thrA 94425 96872 - bifunctional aspartokinase I/homoserine dehydrogenase I multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine%3B functions in a number of amino acid biosynthetic pathways gene gene93 http://www.ncbi.nlm.nih.gov/gene/?term=HI0089 HI0090 HI0090 HI0090 97196 97909 + hypothetical protein similar to PID:882480 SP:P52054 GB:U00096 PID:1789321 gene gene94 http://www.ncbi.nlm.nih.gov/gene/?term=HI0090 HI0091 HI0091 HI0091 97949 99085 - hypothetical protein similar to SP:P42100 PID:563934 PID:904179 GB:AL009126 gene gene95 http://www.ncbi.nlm.nih.gov/gene/?term=HI0091 HI0092 HI0092 HI0092 99094 100353 - hypothetical protein gene gene96 http://www.ncbi.nlm.nih.gov/gene/?term=HI0092 HI0093 HI0093 HI0093 100475 101581 - hypothetical protein similar to SP:P37047 GB:U00096 PID:1552740 PID:1786357 gene gene97 http://www.ncbi.nlm.nih.gov/gene/?term=HI0093 HI0094 HI0094 HI0094 101783 102103 - hypothetical protein gene gene98 http://www.ncbi.nlm.nih.gov/gene/?term=HI0094 HI0095 HI0095 HI0095 102453 103208 - hypothetical protein similar to PID:2104289 gene gene99 http://www.ncbi.nlm.nih.gov/gene/?term=HI0095 HI0096 HI0096 HI0096 103542 104117 + hypothetical protein gene gene100 http://www.ncbi.nlm.nih.gov/gene/?term=HI0096 HI0097 HI0097 hitA hitA 104277 105274 + iron-utilization periplasmic protein hFbpA periplasmic ferric iron binding protein%3B contains a frameshift with respect to purified protein%3B similar to PID:2340838 gene gene101 http://www.ncbi.nlm.nih.gov/gene/?term=HI0097 HI0098 HI0098 hitB hitB 105476 106912 + iron(III) ABC transporter permease similar to GB:M33815 SP:P21409 PID:152861 gene gene102 http://www.ncbi.nlm.nih.gov/gene/?term=HI0098 HI0099 HI0099 hitC hitC 106914 107969 + iron(III) ABC transporter ATP-binding protein similar to PID:1098689 gene gene103 http://www.ncbi.nlm.nih.gov/gene/?term=HI0099 HI0101 HI0101 HI0101 108004 108683 - gene gene104 http://www.ncbi.nlm.nih.gov/gene/?term=HI0101 HI0102 HI0102 dapE dapE 108685 109818 - succinyl-diaminopimelate desuccinylase dapE-encoded N-succinyl-L%2CL-diaminopimelic acid desuccinylase (DapE)%2C catalyzes the hydrolysis of N-succinyl-L%2CLdiaminopimelate L%2CL-SDAP to L%2CL-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica. gene gene105 http://www.ncbi.nlm.nih.gov/gene/?term=HI0102 HI0103 HI0103 HI0103 109846 110190 - hypothetical protein similar to SP:P24178 GB:X57403 PID:41233 GB:U00096 PID:1788815 gene gene106 http://www.ncbi.nlm.nih.gov/gene/?term=HI0103 HI0104 HI0104 htpG htpG 110269 112164 - heat shock protein 90 molecular chaperone gene gene107 http://www.ncbi.nlm.nih.gov/gene/?term=HI0104 HI0105 HI0105 HI0105 112465 113220 + hypothetical protein similar to GB:U00096 SP:P75743 PID:1786928 gene gene108 http://www.ncbi.nlm.nih.gov/gene/?term=HI0105 HI0106 HI0106 ffh ffh 113277 114665 - Signal recognition particle protein similar to SP:P07019 PID:43142 GB:U00096 PID:1788963 gene gene109 http://www.ncbi.nlm.nih.gov/gene/?term=HI0106 HI0107 HI0107 HI0107 114997 116208 + Mg2+/Co2+ transporter similar to GB:U00096 PID:1788966 gene gene110 http://www.ncbi.nlm.nih.gov/gene/?term=HI0107 HI0108 HI0108 HI0108 116337 117230 + hypothetical protein similar to GB:U14003 SP:P39402 PID:537207 GB:U00096 PID:1790826 gene gene111 http://www.ncbi.nlm.nih.gov/gene/?term=HI0108 HI0109 HI0109 HI0109 117319 117660 - hypothetical protein gene gene112 http://www.ncbi.nlm.nih.gov/gene/?term=HI0109 HI0110 HI0110 serS serS 117827 119116 + serine--tRNA ligase catalyzes a two-step reaction%2C first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA gene gene113 http://www.ncbi.nlm.nih.gov/gene/?term=HI0110 HI0111 HI0111 bphH bphH 119451 120080 + glutathione transferase similar to GB:X76500 PID:520921 gene gene114 http://www.ncbi.nlm.nih.gov/gene/?term=HI0111 HI0112 HI0112 HI0112 120092 120388 - hypothetical protein gene gene115 http://www.ncbi.nlm.nih.gov/gene/?term=HI0112 HI0113 HI0113 hemR hemR 120441 122675 + hemin receptor similar to SP:Q56989 PID:1407797 gene gene116 http://www.ncbi.nlm.nih.gov/gene/?term=HI0113 HI0113.2 HI0113.2 HIrrnE5S HIrrnE5S 123431 123559 - 5S ribosomal RNA rRNA gene117 http://www.ncbi.nlm.nih.gov/gene/?term=HI0113.2 HI0113.3 HI0113.3 HIrrnE23S HIrrnE23S 123800 126702 - 23S ribosomal RNA rRNA gene118 http://www.ncbi.nlm.nih.gov/gene/?term=HI0113.3 HI0113.6 HI0113.6 tRNA-Pro-1 tRNA-Pro-1 128892 128968 - tRNA-Pro tRNA gene121 http://www.ncbi.nlm.nih.gov/gene/?term=HI0113.6 HI0113.7 HI0113.7 tRNA-His-1 tRNA-His-1 128990 129065 - tRNA-His tRNA gene122 http://www.ncbi.nlm.nih.gov/gene/?term=HI0113.7 HI0113.8 HI0113.8 tRNA-Arg-1 tRNA-Arg-1 129092 129168 - tRNA-Arg tRNA gene123 http://www.ncbi.nlm.nih.gov/gene/?term=HI0113.8 HI0116 HI0116 HI0116 129317 131453 - gene gene124 http://www.ncbi.nlm.nih.gov/gene/?term=HI0116 HI0116.1 HI0116.1 tRNA-Met-1 tRNA-Met-1 131584 131660 - tRNA-Met tRNA gene125 http://www.ncbi.nlm.nih.gov/gene/?term=HI0116.1 HI0117 HI0117 mltA mltA 132027 132959 + murein transglycosylase A gene gene126 http://www.ncbi.nlm.nih.gov/gene/?term=HI0117 HI0118 HI0118 HI0118 132944 133729 + hypothetical protein similar to GB:D21145 PID:471103 PID:882707 GB:U00096 SP:Q46927 gene gene127 http://www.ncbi.nlm.nih.gov/gene/?term=HI0118 HI0119 HI0119 znuA znuA 133907 134920 + high-affinity zinc transporter substrate-binding protein involved in transport of zinc(II) with ZnuA and C gene gene128 http://www.ncbi.nlm.nih.gov/gene/?term=HI0119 HI0120 HI0120 HI0120 134970 135476 - hypothetical protein gene gene129 http://www.ncbi.nlm.nih.gov/gene/?term=HI0120 HI0121 HI0121 HI0121 135589 136950 - UDP-N-acetylmuramoylalanine-D-glutamate ligase-like protein similar to GB:U14003 SP:P37773 PID:537075 GB:U00096 PID:1790680 gene gene130 http://www.ncbi.nlm.nih.gov/gene/?term=HI0121 HI0122 HI0122 metC metC 137335 138525 - cystathionine beta-lyase catalyzes the formation of L-homocysteine from cystathionine gene gene131 http://www.ncbi.nlm.nih.gov/gene/?term=HI0122 HI0123 HI0123 pgsA pgsA 138800 139357 + phosphatidylglycerophosphate synthase similar to GB:M12299 SP:P06978 PID:473749 GB:U00096 PID:1736571 gene gene132 http://www.ncbi.nlm.nih.gov/gene/?term=HI0123 HI0123.1 HI0123.1 HI0123.1 139513 139588 + tRNA-Gly tRNA gene133 http://www.ncbi.nlm.nih.gov/gene/?term=HI0123.1 HI0123.2 HI0123.2 HI0123.2 139593 139679 + tRNA-Leu tRNA gene134 http://www.ncbi.nlm.nih.gov/gene/?term=HI0123.2 HI0123.3 HI0123.3 HI0123.3 139730 139805 + tRNA-Lys tRNA gene135 http://www.ncbi.nlm.nih.gov/gene/?term=HI0123.3 HI0124 HI0124 ppa ppa 139924 140454 - inorganic pyrophosphatase catalyzes the hydrolysis of pyrophosphate to phosphate gene gene136 http://www.ncbi.nlm.nih.gov/gene/?term=HI0124 HI0125 HI0125 HI0125 140689 142005 + hypothetical protein similar to SP:P32702 PID:396399 GB:U00096 PID:1790499 gene gene137 http://www.ncbi.nlm.nih.gov/gene/?term=HI0125 HI0126 HI0126 fbpC fbpC 142163 143149 - ferric transporter ATP-binding protein Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import gene gene138 http://www.ncbi.nlm.nih.gov/gene/?term=HI0126 HI0129 HI0129 afuB afuB 143193 145091 - ferric transport system permease-like protein gene gene139 http://www.ncbi.nlm.nih.gov/gene/?term=HI0129 HI0131 HI0131 afuA afuA 145395 146435 - ferric ABC transporter protein AfuA%3B similar to PID:1469286 PID:1477455 gene gene140 http://www.ncbi.nlm.nih.gov/gene/?term=HI0131 HI0132 HI0132 udk udk 146601 147242 + uridine kinase functions in pyrimidine salvage%3B pyrimidine ribonucleoside kinase%3B phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor gene gene141 http://www.ncbi.nlm.nih.gov/gene/?term=HI0132 HI0133 HI0133 dcd dcd 147251 147838 + deoxycytidine triphosphate deaminase Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis gene gene142 http://www.ncbi.nlm.nih.gov/gene/?term=HI0133 HI0134 HI0134 HI0134 147842 149017 + hypothetical protein gene gene143 http://www.ncbi.nlm.nih.gov/gene/?term=HI0134 HI0135 HI0135 HI0135 149017 150207 + sugar efflux transporter similar to GB:AE000511 PID:2314345 gene gene144 http://www.ncbi.nlm.nih.gov/gene/?term=HI0135 HI0136 HI0136 engA engA 150287 151801 - GTP-binding protein EngA EngA%3B essential Neisserial GTPase%3B synchronizes cellular events by interacting with multiple targets with tandem G-domains%3B overexpression in Escherichia coli suppresses rrmJ mutation%3B structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains gene gene145 http://www.ncbi.nlm.nih.gov/gene/?term=HI0136 HI0136.1 HI0136.1 tRNA-Asp-1 tRNA-Asp-1 152228 152304 - tRNA-Asp tRNA gene146 http://www.ncbi.nlm.nih.gov/gene/?term=HI0136.1 HI0136.2 HI0136.2 HI0136.2 152328 152404 - tRNA-Asp tRNA gene147 http://www.ncbi.nlm.nih.gov/gene/?term=HI0136.2 HI0137 HI0137 dnaQ dnaQ 152492 153262 - DNA polymerase III subunit epsilon 3'-5' exonuclease of DNA polymerase III gene gene148 http://www.ncbi.nlm.nih.gov/gene/?term=HI0137 HI0138 HI0138 rnhA rnhA 153323 153787 + ribonuclease H An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids gene gene149 http://www.ncbi.nlm.nih.gov/gene/?term=HI0138 HI0139 HI0139 ompP2 ompP2 154039 155118 + outer membrane protein P2 similar to GB:J03359 SP:P20149 gene gene150 http://www.ncbi.nlm.nih.gov/gene/?term=HI0139 HI0140 HI0140 nagA nagA 155307 156452 - N-acetylglucosamine-6-phosphate deacetylase catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate gene gene151 http://www.ncbi.nlm.nih.gov/gene/?term=HI0140 HI0141 HI0141 nagB nagB 156725 157537 - glucosamine-6-phosphate deaminase catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate gene gene152 http://www.ncbi.nlm.nih.gov/gene/?term=HI0141 HI0142 HI0142 nanA nanA 157823 158704 - N-acetylneuraminate lyase catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid gene gene153 http://www.ncbi.nlm.nih.gov/gene/?term=HI0142 HI0143 HI0143 HI0143 158715 159581 - hypothetical protein similar to GB:M81878 SP:P26833 PID:144859 gene gene154 http://www.ncbi.nlm.nih.gov/gene/?term=HI0143 HI0144 HI0144 HI0144 159574 160476 - N-acetylmannosamine kinase catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein gene gene155 http://www.ncbi.nlm.nih.gov/gene/?term=HI0144 HI0145 HI0145 HI0145 160522 161208 - N-acetylmannosamine-6-phosphate 2-epimerase Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate gene gene156 http://www.ncbi.nlm.nih.gov/gene/?term=HI0145 HI0146 HI0146 HI0146 161558 162547 + hypothetical protein similar to SP:P37676 PID:466717 GB:U00096 PID:1790004 gene gene157 http://www.ncbi.nlm.nih.gov/gene/?term=HI0146 HI0147 HI0147 HI0147 162558 164459 + hypothetical protein similar to SP:P37675 PID:466716 GB:U00096 PID:1790003 gene gene158 http://www.ncbi.nlm.nih.gov/gene/?term=HI0147 HI0148 HI0148 HI0148 164623 165762 + N-acetylneuraminic acid mutarotase similar to GB:U14003 SP:P39371 PID:537151 GB:U00096 PID:1790764 gene gene159 http://www.ncbi.nlm.nih.gov/gene/?term=HI0148 HI0148.1 HI0148.1 HI0148.1 165924 166357 + gene gene160 http://www.ncbi.nlm.nih.gov/gene/?term=HI0148.1 HI0150 HI0150 hflC hflC 166400 167287 - hypothetical protein similar to SP:P25661 GB:U00005 PID:436158 PID:537016 GB:U00096 gene gene161 http://www.ncbi.nlm.nih.gov/gene/?term=HI0150 HI0151 HI0151 hflK hflK 167287 168519 - HflK protein similar to SP:P25662 GB:U00005 PID:436157 PID:537015 GB:U00096 gene gene162 http://www.ncbi.nlm.nih.gov/gene/?term=HI0151 HI0152 HI0152 HI0152 168629 169336 - hypothetical protein gene gene163 http://www.ncbi.nlm.nih.gov/gene/?term=HI0152 HI0153 HI0153 dcuB dcuB 169396 170726 - gene gene164 http://www.ncbi.nlm.nih.gov/gene/?term=HI0153 HI0154 HI0154 acpP acpP 170930 171160 - acyl carrier protein carries the fatty acid chain in fatty acid biosynthesis gene gene165 http://www.ncbi.nlm.nih.gov/gene/?term=HI0154 HI0155 HI0155 fabG fabG 171416 172144 - 3-ketoacyl-ACP reductase catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis gene gene166 http://www.ncbi.nlm.nih.gov/gene/?term=HI0155 HI0156 HI0156 fabD fabD 172161 173099 - acyl carrier protein S-malonyltransferase similar to GB:M87040 SP:P25715 GB:Z11565 PID:145887 PID:41364 gene gene167 http://www.ncbi.nlm.nih.gov/gene/?term=HI0156 HI0157 HI0157 fabH fabH 173727 174677 - 3-oxoacyl-ACP synthase III FabH%3B beta-ketoacyl-acyl carrier protein synthase III%3B catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation%3B differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs gene gene168 http://www.ncbi.nlm.nih.gov/gene/?term=HI0157 HI0158 HI0158 rpmF rpmF 174863 175033 - 50S ribosomal protein L32 some L32 proteins have zinc finger motifs consisting of CXXC while others do not gene gene169 http://www.ncbi.nlm.nih.gov/gene/?term=HI0158 HI0159 HI0159 HI0159 175056 175580 - hypothetical protein similar to GB:M29698 SP:P14189 PID:146052 PID:147711 GB:U00096 gene gene170 http://www.ncbi.nlm.nih.gov/gene/?term=HI0159 HI0160 HI0160 psd psd 175737 176609 + phosphatidylserine decarboxylase catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine gene gene171 http://www.ncbi.nlm.nih.gov/gene/?term=HI0160 HI0161 HI0161 gor gor 176718 178088 - glutathione reductase catalyzes the reduction of 2 glutathione to glutathione disulfide%3B maintains high levels of reduced glutathione in the cytosol%3B involved in redox regulation and oxidative defense gene gene172 http://www.ncbi.nlm.nih.gov/gene/?term=HI0161 HI0162 HI0162 HI0162 178304 178903 - lipoprotein similar to GB:U00096 PID:1773118 PID:1786637 gene gene173 http://www.ncbi.nlm.nih.gov/gene/?term=HI0162 HI0163 HI0163 bolA bolA 178997 179308 + transcriptional regulator similar to PID:663269 gene gene174 http://www.ncbi.nlm.nih.gov/gene/?term=HI0163 HI0164 HI0164 HI0164 179599 180942 + Na(+)-translocating NADH-quinone reductase subunit A uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm gene gene175 http://www.ncbi.nlm.nih.gov/gene/?term=HI0164 HI0166 HI0166 nqrB nqrB 180945 182180 + Na(+)-translocating NADH-quinone reductase subunit B uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm gene gene176 http://www.ncbi.nlm.nih.gov/gene/?term=HI0166 HI0167 HI0167 HI0167 182173 182907 + Na(+)-translocating NADH-quinone reductase subunit C uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm gene gene177 http://www.ncbi.nlm.nih.gov/gene/?term=HI0167 HI0168 HI0168 HI0168 182907 183533 + Na(+)-translocating NADH-quinone reductase subunit D Part of the NQR complex which catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions%2C coupled with the transport of Na(+) ions from the cytoplasm to the periplasm gene gene178 http://www.ncbi.nlm.nih.gov/gene/?term=HI0168 HI0170 HI0170 HI0170 183537 184133 + Na(+)-translocating NADH-quinone reductase subunit E Part of the NQR complex which consists of NqrA%2C NqrB%2C NqrC%2C NqrD%2C NqrE and NqrF%3B NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions%2C coupled with the transport of Na(+) ions from the cytoplasm to the periplasm%3B NqrE is probably involved in the second step%2C the conversion of ubisemiquinone to ubiquinol. gene gene179 http://www.ncbi.nlm.nih.gov/gene/?term=HI0170 HI0171 HI0171 nqr6 nqr6 184146 185381 + Na(+)-translocating NADH-quinone reductase subunit F uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm gene gene180 http://www.ncbi.nlm.nih.gov/gene/?term=HI0171 HI0172 HI0172 HI0172 185525 186565 + lipoprotein similar to SP:P33944 PID:405940 GB:U00096 PID:1788543 gene gene181 http://www.ncbi.nlm.nih.gov/gene/?term=HI0172 HI0173 HI0173 HI0173 186568 186828 + hypothetical protein gene gene182 http://www.ncbi.nlm.nih.gov/gene/?term=HI0173 HI0174 HI0174 mnmA mnmA 186840 188096 + tRNA-specific 2-thiouridylase MnmA catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs gene gene183 http://www.ncbi.nlm.nih.gov/gene/?term=HI0174 HI0175 HI0175 HI0175 188140 188874 - hypothetical protein similar to SP:P33644 GB:M29364 PID:1236632 PID:147364 GB:U00096 gene gene184 http://www.ncbi.nlm.nih.gov/gene/?term=HI0175 HI0176 HI0176 rluD rluD 188876 189850 - 23S rRNA pseudouridine synthase D responsible for synthesis of pseudouridine from uracil at positions 1911%2C 1915 and 1917 in 23S ribosomal RNA gene gene185 http://www.ncbi.nlm.nih.gov/gene/?term=HI0176 HI0177 HI0177 HI0177 189958 190746 + hypothetical protein similar to PID:1107833 gene gene186 http://www.ncbi.nlm.nih.gov/gene/?term=HI0177 HI0178 HI0178 HI0178 190826 191308 - hypothetical protein gene gene187 http://www.ncbi.nlm.nih.gov/gene/?term=HI0178 HI0179 HI0179 pflA pflA 191340 192080 - pyruvate formate lyase-activating enzyme 1 activates pyruvate formate-lyase 1 under anaerobic conditions gene gene188 http://www.ncbi.nlm.nih.gov/gene/?term=HI0179 HI0180 HI0180 HI0180 192211 194529 - formate acetyltransferase similar to GB:X08035 SP:P09373 PID:42370 GB:U00096 PID:1651427 gene gene189 http://www.ncbi.nlm.nih.gov/gene/?term=HI0180 HI0181 HI0181 HI0181 194557 195411 - formate transporter similar to SP:P21501 PID:147154 GB:U00096 PID:1651428 PID:1651435 gene gene190 http://www.ncbi.nlm.nih.gov/gene/?term=HI0181 HI0182 HI0182 HI0182 195915 196829 + N-acetyl-D-glucosamine kinase catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine gene gene191 http://www.ncbi.nlm.nih.gov/gene/?term=HI0182 HI0183 HI0183 HI0183 197006 198451 + amino acid carrier protein similar to PID:757741 SP:Q45068 PID:1405464 GB:AL009126 gene gene192 http://www.ncbi.nlm.nih.gov/gene/?term=HI0183 HI0184 HI0184 HI0184 198638 199465 - esterase similar to SP:P10768 gene gene193 http://www.ncbi.nlm.nih.gov/gene/?term=HI0184 HI0185 HI0185 adhC adhC 199474 200610 - alcohol dehydrogenase similar to SP:P25437 PID:887431 GB:U00096 PID:1786552 PID:2443392 gene gene194 http://www.ncbi.nlm.nih.gov/gene/?term=HI0185 HI0186 HI0186 HI0186 200733 201140 + HTH-type transcriptional regulator similar to GB:D26185 SP:P37510 PID:467364 GB:AL009126 gene gene195 http://www.ncbi.nlm.nih.gov/gene/?term=HI0186 HI0187a HI0187a tatA tatA 201358 201627 + Sec-independent protein secretion pathway component TatA gene gene196 http://www.ncbi.nlm.nih.gov/gene/?term=HI0187a HI0187b HI0187b tatB tatB 201591 202151 + sec-independent translocase mediates the export of protein precursors bearing twin-arginine signal peptides gene gene197 http://www.ncbi.nlm.nih.gov/gene/?term=HI0187b HI0188 HI0188 HI0188 202161 202931 + Sec-independent protein translocase protein TatC similar to SP:P27857 GB:M87049 PID:148238 PID:148237 GB:U00096 gene gene198 http://www.ncbi.nlm.nih.gov/gene/?term=HI0188 HI0189 HI0189 gdhA gdhA 203291 204640 + glutamate dehydrogenase converts 2-oxoglutarate to glutamate%3B in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction%3B uses NADPH%3B forms a homohexamer gene gene199 http://www.ncbi.nlm.nih.gov/gene/?term=HI0189 HI0190 HI0190 fur fur 204748 205188 - ferric uptake regulation protein similar to PID:1568605 gene gene200 http://www.ncbi.nlm.nih.gov/gene/?term=HI0190 HI0191 HI0191 fldA fldA 205217 205741 - flavodoxin FldA An electron-transfer protein%3B flavodoxin binds one FMN molecule%2C which serves as a redox-active prosthetic group gene gene201 http://www.ncbi.nlm.nih.gov/gene/?term=HI0191 HI0192 HI0192 seqA seqA 206691 207284 + replication initiation regulator SeqA negative modulator of the initiation of chromosome replication gene gene203 http://www.ncbi.nlm.nih.gov/gene/?term=HI0192 HI0193 HI0193 HI0193 205838 206620 - esterase/lipase similar to GB:U00096 PID:1786902 gene gene202 http://www.ncbi.nlm.nih.gov/gene/?term=HI0193 HI0194 HI0194 menE menE 207287 208645 + 2-succinylbenzoate-CoA ligase similar to GB:L35031 SP:P37353 PID:520813 GB:U00096 PID:1788595 gene gene204 http://www.ncbi.nlm.nih.gov/gene/?term=HI0194 HI0195.1 HI0195.1 HI0195.1 208672 212007 + potassium efflux protein KefA small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer%3B maintains cell turgor through accumulation and release of potassium%3B large protein class of MscS gene gene205 http://www.ncbi.nlm.nih.gov/gene/?term=HI0195.1 HI0196 HI0196 aroC aroC 212017 213090 + chorismate synthase catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis gene gene206 http://www.ncbi.nlm.nih.gov/gene/?term=HI0196 HI0197 HI0197 mepA mepA 213175 214035 + penicillin-insensitive murein endopeptidase D-alanyl-D-alanine endopeptidase%3B functions in hydrolyzing cell wall peptidoglycan%3B similar to LAS metallopeptidases%3B forms a dimer in periplasm gene gene207 http://www.ncbi.nlm.nih.gov/gene/?term=HI0197 HI0198 HI0198 HI0198 214053 214820 + hypothetical protein similar to SP:P14008 PID:41996 GB:U00096 PID:1788667 gene gene208 http://www.ncbi.nlm.nih.gov/gene/?term=HI0198 HI0199 HI0199 msbB msbB 214867 215823 + lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase Transfers myristate or laurate%2C activated on ACP%2C to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA gene gene209 http://www.ncbi.nlm.nih.gov/gene/?term=HI0199 HI0200m HI0200m selD selD 215881 216921 + selenophosphate synthetase catalyzes the formation of selenophosphate from selenide and ATP gene gene210 http://www.ncbi.nlm.nih.gov/gene/?term=HI0200m HI0201 HI0201 rplS rplS 217030 217380 - 50S ribosomal protein L19 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site gene gene211 http://www.ncbi.nlm.nih.gov/gene/?term=HI0201 HI0202 HI0202 trmD trmD 217417 218157 - tRNA (guanine-N(1)-)-methyltransferase methylates guanosine-37 in various tRNAs%3B uses S-adenosyl-L-methionine to transfer methyl group to tRNA gene gene212 http://www.ncbi.nlm.nih.gov/gene/?term=HI0202 HI0203 HI0203 rimM rimM 218195 218722 - 16S rRNA-processing protein RimM Essential for efficient processing of 16S rRNA gene gene213 http://www.ncbi.nlm.nih.gov/gene/?term=HI0203 HI0204 HI0204 rpsP rpsP 218767 219015 - 30S ribosomal protein S16 binds to lower part of 30S body where it stabilizes two domains%3B required for efficient assembly of 30S%3B in Escherichia coli this protein has nuclease activity gene gene214 http://www.ncbi.nlm.nih.gov/gene/?term=HI0204 HI0205 HI0205 HI0205 219308 220081 + hypothetical protein gene gene215 http://www.ncbi.nlm.nih.gov/gene/?term=HI0205 HI0206 HI0206 HI0206 220104 221915 + NAD nucleotidase similar to SP:P29240 PID:62772 gene gene216 http://www.ncbi.nlm.nih.gov/gene/?term=HI0206 HI0207 HI0207 aroK aroK 222200 222742 + shikimate kinase catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis gene gene217 http://www.ncbi.nlm.nih.gov/gene/?term=HI0207 HI0208 HI0208 aroB aroB 222762 223850 + 3-dehydroquinate synthase catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate%3B functions in aromatic amino acid biosynthesis gene gene218 http://www.ncbi.nlm.nih.gov/gene/?term=HI0208 HI0209 HI0209 dam dam 223852 224712 + DNA adenine methylase similar to GB:J01600 SP:P00475 GB:V00272 GB:Z19601 PID:145706 gene gene219 http://www.ncbi.nlm.nih.gov/gene/?term=HI0209 HI0211 HI0211 pgpB pgpB 225814 226539 - phosphatidylglycerophosphatase B similar to GB:M23628 SP:P18201 PID:450384 GB:U00096 PID:1742092 gene gene220 http://www.ncbi.nlm.nih.gov/gene/?term=HI0211 HI0212 HI0212 ribA ribA 226608 227258 + GTP cyclohydrolase II catalyzes the conversion of GTP to formate and 2%2C5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate gene gene221 http://www.ncbi.nlm.nih.gov/gene/?term=HI0212 HI0213 HI0213 HI0213 227577 229121 - oligopeptide transporter substrate-binding protein similar to SP:P06202 GB:X05491 GB:X52093 PID:47802 PID:47808 gene gene222 http://www.ncbi.nlm.nih.gov/gene/?term=HI0213 HI0214 HI0214 prlC prlC 229603 231642 + oligopeptidase A similar to SP:P27298 GB:M93984 PID:451277 PID:466635 GB:U00096 gene gene223 http://www.ncbi.nlm.nih.gov/gene/?term=HI0214 HI0215 HI0215 HI0215 231874 233393 + gene gene224 http://www.ncbi.nlm.nih.gov/gene/?term=HI0215 HI0216 HI0216 hsdS hsdS 233477 234634 + type I restriction/modification specificity protein similar to GB:X73984 PID:393411 gene gene225 http://www.ncbi.nlm.nih.gov/gene/?term=HI0216 HI0217 HI0217 HI0217 234763 235293 + hypothetical protein similar to PID:984584 GB:U00096 SP:Q47152 PID:1552796 PID:1786422 gene gene226 http://www.ncbi.nlm.nih.gov/gene/?term=HI0217 HI0218 HI0218 HI0218 235441 238519 + gene gene227 http://www.ncbi.nlm.nih.gov/gene/?term=HI0218 HI0219 HI0219 HI0219 238674 239303 - hypothetical protein similar to GB:S68137 SP:P46928 PID:469476 gene gene228 http://www.ncbi.nlm.nih.gov/gene/?term=HI0219 HI0219a HI0219a HI0219a 239516 240229 - two component signal transduction system protein gene gene229 http://www.ncbi.nlm.nih.gov/gene/?term=HI0219a HI0220.1 HI0220.1 birA birA 247910 248818 - biotin--protein ligase catalyzes the formation of biotinyl-5'-AMP%2C also acts as a transcriptional repressor of the biotin operon gene gene235 http://www.ncbi.nlm.nih.gov/gene/?term=HI0220.1 HI0220.2 HI0220.2 HI0220.2 241428 242015 - hypothetical protein gene gene230 http://www.ncbi.nlm.nih.gov/gene/?term=HI0220.2 HI0220.3 HI0220.3 HIrrnF5S HIrrnF5S 242269 242397 - 5S ribosomal RNA rRNA gene231 http://www.ncbi.nlm.nih.gov/gene/?term=HI0220.3 HI0220.4 HI0220.4 HIrrnF23S HIrrnF23S 242637 245539 - 23S ribosomal RNA rRNA gene232 http://www.ncbi.nlm.nih.gov/gene/?term=HI0220.4 HI0220.5 HI0220.5 HIrrnF16S HIrrnF16S 246009 247557 - 16S ribosomal RNA rRNA gene234 http://www.ncbi.nlm.nih.gov/gene/?term=HI0220.5 HI0220.6 HI0220.6 HI0220.6 245806 245881 - tRNA-Glu tRNA gene233 http://www.ncbi.nlm.nih.gov/gene/?term=HI0220.6 HI0221 HI0221 guaB guaB 248948 250414 + inosine 5'-monophosphate dehydrogenase catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate gene gene236 http://www.ncbi.nlm.nih.gov/gene/?term=HI0221 HI0221.1 HI0221.1 HI0221.1 250524 251015 + inosine-5'-monophosphate dehydrogenase-like protein similar to C-terminus of HI0221 gene gene237 http://www.ncbi.nlm.nih.gov/gene/?term=HI0221.1 HI0222 HI0222 guaA guaA 251125 252696 + GMP synthase contains glutamine-hydrolyzing domain and glutamine amidotransferase%3B GMP-binding domain%3B functions to produce GMP from XMP in the IMP pathway gene gene238 http://www.ncbi.nlm.nih.gov/gene/?term=HI0222 HI0223 HI0223 HI0223 252758 253660 - hypothetical protein similar to SP:P27844 gene gene239 http://www.ncbi.nlm.nih.gov/gene/?term=HI0223 HI0224 HI0224 HI0224 253772 254233 + transcriptional regulator similar to SP:P55658 PID:2182633 gene gene240 http://www.ncbi.nlm.nih.gov/gene/?term=HI0224 HI0225 HI0225 nhaA nhaA 254272 255474 - pH-dependent sodium/proton antiporter exports sodium by using the electrochemical proton gradient to allow protons into the cell%3B functions in adaptation to high salinity and alkaline pH%3B activity increases at higher pH%3B downregulated at acidic pH gene gene241 http://www.ncbi.nlm.nih.gov/gene/?term=HI0225 HI0226 HI0226 brnQ brnQ 255662 256972 + branched-chain amino acid ABC transporter similar to SP:P37011 GB:U00096 PID:1657597 PID:1773085 PID:1786601 gene gene242 http://www.ncbi.nlm.nih.gov/gene/?term=HI0226 HI0227 HI0227 HI0227 257080 257547 - hypothetical protein similar to SP:P37673 PID:466714 GB:U00096 PID:1790001 gene gene243 http://www.ncbi.nlm.nih.gov/gene/?term=HI0227 HI0228 HI0228 HI0228 257574 258022 - gene gene244 http://www.ncbi.nlm.nih.gov/gene/?term=HI0228 HI0229 HI0229 pnp pnp 258296 260425 + polynucleotide phosphorylase/polyadenylase similar to GB:J02638 SP:P05055 GB:M14425 GB:X00761 PID:147749 gene gene245 http://www.ncbi.nlm.nih.gov/gene/?term=HI0229 HI0230 HI0230 HI0230 260507 261451 + lipoprotein NlpI lipoprotein that appears to be involved in cell division%3B interacts with the periplasmic protease Prc and may be activated by protease processing gene gene246 http://www.ncbi.nlm.nih.gov/gene/?term=HI0230 HI0231 HI0231 deaD deaD 261572 263413 + ATP-dependent RNA helicase similar to SP:P23304 GB:M63288 GB:U03750 PID:432406 PID:606102 gene gene247 http://www.ncbi.nlm.nih.gov/gene/?term=HI0231 HI0232 HI0232 HI0232 263591 264979 + transglycosylase YfhD%3B uncharacterized member of the transglycosylase slt family%3B part of the rob operon%2C which plays a role in cellular resistance to antibiotics%2C bactericidal agents%2C and organic solvents%3B unknown function gene gene248 http://www.ncbi.nlm.nih.gov/gene/?term=HI0232 HI0234 HI0234 HI0234 265270 265567 - gene gene249 http://www.ncbi.nlm.nih.gov/gene/?term=HI0234 HI0235 HI0235 HI0235 265624 265833 - hypothetical protein similar to GB:L29458 SP:P36675 PID:473421 gene gene250 http://www.ncbi.nlm.nih.gov/gene/?term=HI0235 HI0236 HI0236 HI0236 265901 266251 - arsenate reductase similar to PID:1805555 gene gene251 http://www.ncbi.nlm.nih.gov/gene/?term=HI0236 HI0237 HI0237 perM perM 266330 267378 + gene gene252 http://www.ncbi.nlm.nih.gov/gene/?term=HI0237 HI0239 HI0239 secF secF 267493 268470 - preprotein translocase subunit SecF forms a complex with SecD and YajC%3B SecDFyajC stimulates the proton motive force-driven protein translocation%3B seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane%3B in some organisms%2C such as Bacillus subtilis%2C SecD is fused to SecF gene gene253 http://www.ncbi.nlm.nih.gov/gene/?term=HI0239 HI0240 HI0240 secD secD 268478 270328 - preprotein translocase subunit SecD part of the preprotein secretory system%3B when complexed with proteins SecF and YajC%2C SecDFyajC stimulates the proton motive force-driven protein translocation%2C and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane gene gene254 http://www.ncbi.nlm.nih.gov/gene/?term=HI0240 HI0241 HI0241 yajC yajC 270398 270691 - preprotein translocase subunit YajC member of preprotein translocase%3B forms a heterotrimer with SecD and SecF%3B links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex gene gene255 http://www.ncbi.nlm.nih.gov/gene/?term=HI0241 HI0242 HI0242 HI0242 270799 271020 - hypothetical protein similar to GB:L77117 SP:Q58397 PID:1591652 gene gene256 http://www.ncbi.nlm.nih.gov/gene/?term=HI0242 HI0243 HI0243 HI0243 271017 271535 - hypothetical protein gene gene257 http://www.ncbi.nlm.nih.gov/gene/?term=HI0243 HI0244 HI0244 tgt tgt 271600 272748 - queuine tRNA-ribosyltransferase Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp%2C -Asn%2C -His and -Tyr) gene gene258 http://www.ncbi.nlm.nih.gov/gene/?term=HI0244 HI0245 HI0245 queA queA 273092 274183 - S-adenosylmethionine:tRNA ribosyltransferase-isomerase Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step gene gene259 http://www.ncbi.nlm.nih.gov/gene/?term=HI0245 HI0246 HI0246 HI0246 274307 274753 - hypothetical protein gene gene260 http://www.ncbi.nlm.nih.gov/gene/?term=HI0246 HI0247 HI0247 HI0247 274892 279121 - similar to adhesin%3B contains point mutation that is not a result of a sequencing artifact%3B similar to GB:M87490 GB:X64357 PID:148909 gene gene261 http://www.ncbi.nlm.nih.gov/gene/?term=HI0247 HI0247.1 HI0247.1 tRNA-Ser-2 tRNA-Ser-2 288153 288242 - tRNA-Ser tRNA gene271 http://www.ncbi.nlm.nih.gov/gene/?term=HI0247.1 HI0249 HI0249 uvrA uvrA 279439 282270 - excinuclease ABC subunit A The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB%2C the uvrA molecules dissociate gene gene262 http://www.ncbi.nlm.nih.gov/gene/?term=HI0249 HI0250 HI0250 ssb ssb 282424 282930 + single-stranded DNA-binding protein binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA gene gene263 http://www.ncbi.nlm.nih.gov/gene/?term=HI0250 HI0251 HI0251 HI0251 283108 283920 - TonB similar to GB:U04996 gene gene264 http://www.ncbi.nlm.nih.gov/gene/?term=HI0251 HI0252 HI0252 exbD exbD 283930 284373 - biopolymer transport protein similar to PID:555672 PID:1573218 gene gene265 http://www.ncbi.nlm.nih.gov/gene/?term=HI0252 HI0253 HI0253 exbB exbB 284377 284829 - transport protein ExbB similar to PID:555671 gene gene266 http://www.ncbi.nlm.nih.gov/gene/?term=HI0253 HI0254 HI0254 bcp bcp 284998 285465 - thioredoxin-dependent thiol peroxidase bacterioferritin comigratory protein%3B thiol peroxidase%3B thioredoxin-dependent%3B hydroperoxide peroxidase%3B in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide%3B contains an active site cysteine gene gene267 http://www.ncbi.nlm.nih.gov/gene/?term=HI0254 HI0255 HI0255 dapA dapA 285566 286462 + 4-hydroxy-tetrahydrodipicolinate synthase catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis gene gene268 http://www.ncbi.nlm.nih.gov/gene/?term=HI0255 HI0256 HI0256 HI0256 286573 287220 + lipoprotein similar to SP:P21167 PID:147409 PID:42126 GB:U00096 PID:1788822 gene gene269 http://www.ncbi.nlm.nih.gov/gene/?term=HI0256 HI0257 HI0257 HI0257 287390 287713 + hypothetical protein structural determination suggests similarity to dsRNA-binding proteins%3B similar to YfiA%3B similar to SP:P17160 GB:X05888 GB:X16334 PID:39270 PID:39276 gene gene270 http://www.ncbi.nlm.nih.gov/gene/?term=HI0257 HI0258 HI0258 HI0258 288442 289434 - glycosyl transferase similar to PID:1857120 gene gene272 http://www.ncbi.nlm.nih.gov/gene/?term=HI0258 HI0260 HI0260 HI0260 289511 290098 - deoxyribonucleotide triphosphate pyrophosphatase HAM1-like protein%3B Rec-dependent growth%3B RgdB%3B yggV%3B it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine gene gene273 http://www.ncbi.nlm.nih.gov/gene/?term=HI0260 HI0260.1 HI0260.1 HI0260.1 290110 290835 - 3-deoxy-D-manno-octulosonic-acid kinase catalyzes the phosphorylation of 3-deoxy-D-manno-octulosonic acid at the 4-OH position gene gene274 http://www.ncbi.nlm.nih.gov/gene/?term=HI0260.1 HI0261 HI0261 HI0261 290912 291955 + lipopolysaccharide biosynthesis protein similar to GB:L21026 PID:311045 gene gene275 http://www.ncbi.nlm.nih.gov/gene/?term=HI0261 HI0262 HI0262 HI0262 292279 294450 + heme-hemopexin utilization protein C similar to SP:P45357 PID:595326 gene gene276 http://www.ncbi.nlm.nih.gov/gene/?term=HI0262 HI0263 HI0263 hxuB hxuB 294525 296222 + heme/hemopexin-binding protein B similar to SP:P45356 PID:1573229 gene gene277 http://www.ncbi.nlm.nih.gov/gene/?term=HI0263 HI0264 HI0264 hxuA hxuA 296234 298951 + heme-hemopexin utilization protein A similar to GB:U08348 PID:540014 gene gene278 http://www.ncbi.nlm.nih.gov/gene/?term=HI0264 HI0265 HI0265 HI0265 299047 299403 - dihydroneopterin aldolase similar to SP:P31055 PID:882580 GB:U00096 PID:1789438 gene gene279 http://www.ncbi.nlm.nih.gov/gene/?term=HI0265 HI0266 HI0266 HI0266 299486 300085 + glycerol-3-phosphate acyltransferase PlsY involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis%3B functions with PlsX gene gene280 http://www.ncbi.nlm.nih.gov/gene/?term=HI0266 HI0267 HI0267 narQ narQ 300127 301830 + nitrate/nitrite sensor protein NarQ similar to GB:M94724 SP:P27896 GB:X65714 PID:146928 PID:581139 gene gene281 http://www.ncbi.nlm.nih.gov/gene/?term=HI0267 HI0268 HI0268 murB murB 301840 302865 + UDP-N-acetylenolpyruvoylglucosamine reductase catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis gene gene282 http://www.ncbi.nlm.nih.gov/gene/?term=HI0268 HI0269 HI0269 rpoH rpoH 302991 303836 + RNA polymerase factor sigma-32 binds with the catalytic core of RNA polymerase to produce the holoenzyme%3B this sigma factor is responsible for the expression of heat shock promoters gene gene283 http://www.ncbi.nlm.nih.gov/gene/?term=HI0269 HI0270 HI0270 HI0270 303876 304808 - hypothetical protein similar to SP:P33371 PID:405871 GB:U00096 PID:1788462 gene gene284 http://www.ncbi.nlm.nih.gov/gene/?term=HI0270 HI0271 HI0271 djlA djlA 304808 305674 - Dna-J like membrane chaperone protein functions as a co-chaperone with DnaK%3B involved in regulation of colanic acid capsule%3B inner membrane protein%3B dimerized via transmembrane domain%3B J-like domain is cytoplasmic and can functionally substitute for DnaJ%3B stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system gene gene285 http://www.ncbi.nlm.nih.gov/gene/?term=HI0271 HI0272 HI0272 pyrE pyrE 305753 306394 - orotate phosphoribosyltransferase involved in fifth step of pyrimidine biosynthesis%3B converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate gene gene286 http://www.ncbi.nlm.nih.gov/gene/?term=HI0272 HI0273 HI0273 rph rph 306418 307134 - ribonuclease PH RNase PH%3B tRNA nucleotidyltransferase%3B forms hexamers in Bacillus subtilis%3B phosphoroltic 3'-5' exoribonuclease%3B involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs gene gene287 http://www.ncbi.nlm.nih.gov/gene/?term=HI0273 HI0273.1 HI0273.1 tRNA-Ala-1 tRNA-Ala-1 307279 307354 - tRNA-Ala tRNA gene288 http://www.ncbi.nlm.nih.gov/gene/?term=HI0273.1 HI0274 HI0274 gltX gltX 307435 308877 - glutamate--tRNA ligase Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation gene gene289 http://www.ncbi.nlm.nih.gov/gene/?term=HI0274 HI0274.1 HI0274.1 HI0274.1 309048 309123 + tRNA-Val tRNA gene290 http://www.ncbi.nlm.nih.gov/gene/?term=HI0274.1 HI0274.2 HI0274.2 HI0274.2 309167 309242 + tRNA-Val tRNA gene291 http://www.ncbi.nlm.nih.gov/gene/?term=HI0274.2 HI0274.3 HI0274.3 HI0274.3 309301 309376 + tRNA-Val tRNA gene292 http://www.ncbi.nlm.nih.gov/gene/?term=HI0274.3 HI0274.4 HI0274.4 tRNA-Val-4 tRNA-Val-4 309429 309504 + tRNA-Val tRNA gene293 http://www.ncbi.nlm.nih.gov/gene/?term=HI0274.4 HI0275 HI0275 HI0275 309627 311282 + hypothetical protein gene gene294 http://www.ncbi.nlm.nih.gov/gene/?term=HI0275 HI0276 HI0276 rbn rbn 311302 312111 - ribonuclease BN RNase BN%3B required for 3' maturation of certain phage T4-encoded tRNAs%3B forms a dimer%3B specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence%3B 3' to 5' exoribonuclease gene gene295 http://www.ncbi.nlm.nih.gov/gene/?term=HI0276 HI0277 HI0277 HI0277 312108 312593 - hypothetical protein similar to GB:L20251 SP:P37052 PID:410154 GB:U00096 PID:1787484 gene gene296 http://www.ncbi.nlm.nih.gov/gene/?term=HI0277 HI0279m HI0279m HI0279m 312596 313259 - gene gene297 http://www.ncbi.nlm.nih.gov/gene/?term=HI0279m HI0280 HI0280 udp udp 313495 314253 + uridine phosphorylase catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate%3B involved in the pyrimidine salvage pathway gene gene298 http://www.ncbi.nlm.nih.gov/gene/?term=HI0280 HI0281 HI0281 HI0281 314478 315794 - transporter similar to SP:P37643 PID:466660 GB:U00096 PID:1789941 gene gene299 http://www.ncbi.nlm.nih.gov/gene/?term=HI0281 HI0282 HI0282 HI0282 315850 316593 - acyl-CoA thioester hydrolase YfbB catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA gene gene300 http://www.ncbi.nlm.nih.gov/gene/?term=HI0282 HI0283 HI0283 menD menD 316654 318360 - 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase SEPHCHC synthase%3B forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis gene gene301 http://www.ncbi.nlm.nih.gov/gene/?term=HI0283 HI0285 HI0285 menF menF 318376 319668 - menaquinone-specific isochorismate synthase synthesizes isochorismate acid from chorismate gene gene302 http://www.ncbi.nlm.nih.gov/gene/?term=HI0285 HI0286 HI0286 HI0286 319804 321018 + aminotransferase AlaT broad specificity%3B family IV%3B in Corynebacterium glutamicum this protein can use glutamate%2C 2-aminobutyrate%2C and aspartate as amino donors and pyruvate as the acceptor gene gene303 http://www.ncbi.nlm.nih.gov/gene/?term=HI0286 HI0287 HI0287 mtr mtr 321135 322391 + tryptophan-specific transport protein similar to GB:M58338 SP:P22306 GB:M59862 PID:146894 PID:146896 gene gene304 http://www.ncbi.nlm.nih.gov/gene/?term=HI0287 HI0288 HI0288 sdaA sdaA 322500 323867 - L-serine deaminase similar to GB:M28695 SP:P16095 PID:290464 GB:U00096 PID:1736451 gene gene305 http://www.ncbi.nlm.nih.gov/gene/?term=HI0288 HI0289 HI0289 sdaC sdaC 323902 325140 - serine transporter similar to SP:P36559 GB:U01233 PID:402256 PID:882691 GB:U00096 gene gene306 http://www.ncbi.nlm.nih.gov/gene/?term=HI0289 HI0290 HI0290 HI0290 325363 327531 - cation-transporting ATPase similar to GB:AL009126 gene gene307 http://www.ncbi.nlm.nih.gov/gene/?term=HI0290 HI0291 HI0291 HI0291 327506 327712 - mercury transport-like protein gene gene308 http://www.ncbi.nlm.nih.gov/gene/?term=HI0291 HI0292 HI0292 merP merP 327787 327993 - mercuric ion scavenger protein similar to GB:X73112 PID:483769 SP:Q51770 gene gene309 http://www.ncbi.nlm.nih.gov/gene/?term=HI0292 HI0293 HI0293 HI0293 328070 328456 + MerR family transcriptional regulator similar to GB:U00096 SP:P77565 PID:1773169 PID:1786695 gene gene310 http://www.ncbi.nlm.nih.gov/gene/?term=HI0293 HI0294 HI0294 metJ metJ 328470 328787 - transcriptional repressor protein MetJ when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis gene gene311 http://www.ncbi.nlm.nih.gov/gene/?term=HI0294 HI0295 HI0295 rho rho 329034 330296 + transcription termination factor Rho An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes gene gene312 http://www.ncbi.nlm.nih.gov/gene/?term=HI0295 HI0296 HI0296 hopD hopD 330350 331042 - type 4 prepilin-like protein specific leader peptidase similar to SP:P25960 GB:L28106 PID:145410 PID:451905 PID:606269 gene gene313 http://www.ncbi.nlm.nih.gov/gene/?term=HI0296 HI0297 HI0297 HI0297 331039 332259 - type IV pilin secretion protein similar to GB:M32066 SP:P22609 PID:151066 gene gene314 http://www.ncbi.nlm.nih.gov/gene/?term=HI0297 HI0298 HI0298 HI0298 332256 333650 - protein transport protein similar to GB:M32066 SP:P22608 GB:S43866 PID:151065 gene gene315 http://www.ncbi.nlm.nih.gov/gene/?term=HI0298 HI0299 HI0299 HI0299 333647 334096 - prepilin peptidase-dependent protein D similar to GB:D26562 SP:P36647 GB:L28105 PID:473777 PID:456042 gene gene316 http://www.ncbi.nlm.nih.gov/gene/?term=HI0299 HI0300 HI0300 ampD ampD 334212 334766 + 1%2C6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD similar to GB:D26562 SP:P13016 GB:L28105 GB:X15237 PID:40908 gene gene317 http://www.ncbi.nlm.nih.gov/gene/?term=HI0300 HI0301 HI0301 HI0301 335399 336298 + hemolysin similar to GB:U00096 PID:1778577 PID:1786879 gene gene318 http://www.ncbi.nlm.nih.gov/gene/?term=HI0301 HI0302 HI0302 lnt lnt 336321 337850 + apolipoprotein N-acyltransferase Transfers the fatty acyl group on membrane lipoproteins gene gene319 http://www.ncbi.nlm.nih.gov/gene/?term=HI0302 HI0303 HI0303 HI0303 337900 338637 + 16S ribosomal RNA methyltransferase RsmE in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA%3B cells lacking this function can grow%2C but are outcompeted by wild-type%3B SAM-dependent m(3)U1498 methyltransferase gene gene320 http://www.ncbi.nlm.nih.gov/gene/?term=HI0303 HI0304 HI0304 HI0304 338634 339194 + hypothetical protein similar to PID:882477 SP:P52049 GB:U00096 PID:1789317 gene gene321 http://www.ncbi.nlm.nih.gov/gene/?term=HI0304 HI0305 HI0305 HI0305 339194 339613 + Holliday junction resolvase-like protein similar to RuvC resolvase with substantial differences%3B NMR structural information suggests this protein is monomeric%3B unknown cellular function gene gene322 http://www.ncbi.nlm.nih.gov/gene/?term=HI0305 HI0306 HI0306 rdgC rdgC 339663 340571 - recombination associated protein Required for efficient pilin antigenic variation gene gene323 http://www.ncbi.nlm.nih.gov/gene/?term=HI0306 HI0307 HI0307 proC proC 340637 341452 + pyrroline-5-carboxylate reductase catalyzes the formation of L-proline from pyrroline-5-carboxylate gene gene324 http://www.ncbi.nlm.nih.gov/gene/?term=HI0307 HI0308 HI0308 HI0308 341452 342618 + 3-phenylpropionic acid transporter transporter of 3-phenylpropionate across the inner membrane%3B member of the major facilitator superfamily of transporters gene gene325 http://www.ncbi.nlm.nih.gov/gene/?term=HI0308 HI0309 HI0309 xerD xerD 342649 343542 + site-specific tyrosine recombinase XerD site-specific tyrosine recombinase which cuts and rejoins DNA molecules%3B binds cooperatively to specific DNA consensus sites%3B forms a heterotetrameric complex with XerC%3B XerCD exhibit similar sequences%3B essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation%3B XerD specifically exchanges the bottom strands%3B cell division protein FtsK may regulate the XerCD complex%3B enzyme from Streptococcus group has unusual active site motifs gene gene326 http://www.ncbi.nlm.nih.gov/gene/?term=HI0309 HI0310 HI0310 HI0310 343715 344002 + hypothetical protein gene gene327 http://www.ncbi.nlm.nih.gov/gene/?term=HI0310 HI0312 HI0312 ruvB ruvB 344054 345061 - Holliday junction DNA helicase RuvB promotes strand exchange during homologous recombination%3B RuvAB complex promotes branch migration%3B RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences%3B forms hexameric rings around opposite DNA arms%3B requires ATP for branch migration and orientation of RuvAB complex determines direction of migration gene gene328 http://www.ncbi.nlm.nih.gov/gene/?term=HI0312 HI0313 HI0313 ruvA ruvA 345069 345683 - Holliday junction DNA helicase RuvA plays an essential role in ATP-dependent branch migration of the Holliday junction gene gene329 http://www.ncbi.nlm.nih.gov/gene/?term=HI0313 HI0314 HI0314 ruvC ruvC 345746 346318 - Holliday junction resolvase endonuclease%3B resolves Holliday structures%3B forms a complex of RuvABC%3B the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration%3B RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity gene gene330 http://www.ncbi.nlm.nih.gov/gene/?term=HI0314 HI0315 HI0315 HI0315 346365 347105 - hypothetical protein similar to GB:D10165 SP:P24237 PID:216652 PID:42173 GB:U00096 gene gene331 http://www.ncbi.nlm.nih.gov/gene/?term=HI0315 HI0316 HI0316 ntpA ntpA 347265 347729 - dATP pyrophosphohydrolase converts dATP to dAMP and pyrophosphate gene gene332 http://www.ncbi.nlm.nih.gov/gene/?term=HI0316 HI0317 HI0317 aspS aspS 347763 349529 - aspartate--tRNA ligase catalyzes a two-step reaction%2C first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B contains discriminating and non-discriminating subtypes gene gene333 http://www.ncbi.nlm.nih.gov/gene/?term=HI0317 HI0318 HI0318 HI0318 349748 350266 + hypothetical protein similar to SP:P54158 PID:1256620 GB:AL009126 gene gene334 http://www.ncbi.nlm.nih.gov/gene/?term=HI0318 HI0319 HI0319 yecO yecO 350319 351044 + S-adenosyl-L-methionine-dependent methyltransferase YecO%3B contains bound cofactor S-adenosyl-L-homocysteine%3B similar to GB:U00096 PID:1788177 gene gene335 http://www.ncbi.nlm.nih.gov/gene/?term=HI0319 HI0321 HI0321 vapB vapB 351138 351374 + virulence-associated protein B similar to GB:L22308 GB:L31763 GB:M74565 PID:145069 PID:438535 gene gene336 http://www.ncbi.nlm.nih.gov/gene/?term=HI0321 HI0322 HI0322 HI0322 351371 351775 + virulence-associated protein C similar to GB:L22308 GB:L31763 GB:M74565 PID:145068 PID:438534 gene gene337 http://www.ncbi.nlm.nih.gov/gene/?term=HI0322 HI0323 HI0323 gloA gloA 351842 352249 + lactoylglutathione lyase similar to GB:U00096 SP:Q59384 PID:1354845 PID:1711245 PID:1787940 gene gene338 http://www.ncbi.nlm.nih.gov/gene/?term=HI0323 HI0324 HI0324 rnt rnt 352323 353012 + ribonuclease T Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A) gene gene339 http://www.ncbi.nlm.nih.gov/gene/?term=HI0324 HI0325 HI0325 HI0325 353326 354678 + hypothetical protein similar to GB:AL009126 gene gene340 http://www.ncbi.nlm.nih.gov/gene/?term=HI0325 HI0326 HI0326 HI0326 354711 355297 + gene gene341 http://www.ncbi.nlm.nih.gov/gene/?term=HI0326 HI0326.1 HI0326.1 HI0326.1 355348 355437 - tRNA-Ser tRNA gene342 http://www.ncbi.nlm.nih.gov/gene/?term=HI0326.1 HI0328 HI0328 efp efp 355648 356214 - elongation factor P Involved in peptide bond synthesis%3B alters the affinity of the ribosome for aminoacyl-tRNA gene gene343 http://www.ncbi.nlm.nih.gov/gene/?term=HI0328 HI0329 HI0329 HI0329 356252 357268 + hypothetical protein similar to GB:U14003 SP:P39280 PID:536990 GB:U00096 PID:1790589 gene gene344 http://www.ncbi.nlm.nih.gov/gene/?term=HI0329 HI0330 HI0330 oapA oapA 357367 358662 + opacity associated protein similar to GB:L42023 SP:P44415 PID:1003551 PID:1222255 PID:595942 gene gene345 http://www.ncbi.nlm.nih.gov/gene/?term=HI0330 HI0331 HI0331 oapB oapB 358722 359126 + opacity associated protein OapB similar to GB:L42023 SP:P44416 PID:1003553 PID:1222256 PID:595943 gene gene346 http://www.ncbi.nlm.nih.gov/gene/?term=HI0331 HI0332 HI0332 recO recO 359129 359839 + DNA repair protein RecO involved in DNA repair and RecFOR pathway recombination%3B RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA gene gene347 http://www.ncbi.nlm.nih.gov/gene/?term=HI0332 HI0333 HI0333 rumA rumA 359839 361155 + 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA%3B binds an iron-sulfur cluster [4Fe-4S] gene gene348 http://www.ncbi.nlm.nih.gov/gene/?term=HI0333 HI0334 HI0334 relA relA 361233 363464 + GTP pyrophosphokinase similar to GB:J04039 SP:P11585 PID:147562 PID:882678 GB:U00096 gene gene349 http://www.ncbi.nlm.nih.gov/gene/?term=HI0334 HI0335 HI0335 dgkA dgkA 363479 363835 + diacylglycerol kinase similar to GB:U00006 SP:P00556 GB:K00127 PID:396377 PID:457112 gene gene350 http://www.ncbi.nlm.nih.gov/gene/?term=HI0335 HI0336 HI0336 mogA mogA 363918 364511 + molybdenum cofactor biosynthesis protein MogA forms a trimer%3B related to eukaryotic protein gephyrin%3B functions during molybdenum cofactor biosynthesis gene gene351 http://www.ncbi.nlm.nih.gov/gene/?term=HI0336 HI0337 HI0337 glnB glnB 364513 364851 + nitrogen regulatory protein P-II similar to GB:U00096 PID:1788904 PID:1799977 gene gene352 http://www.ncbi.nlm.nih.gov/gene/?term=HI0337 HI0338 HI0338 HI0338 364851 365897 + hypothetical protein similar to GB:U00096 PID:1787885 gene gene353 http://www.ncbi.nlm.nih.gov/gene/?term=HI0338 HI0339 HI0339 priA priA 365938 368130 - primosome assembly protein PriA binding of PriA to forked DNA starts the assembly of the primosome%2C also possesses 3'-5' helicase activity gene gene354 http://www.ncbi.nlm.nih.gov/gene/?term=HI0339 HI0340 HI0340 trmB trmB 368213 368953 + tRNA (guanine-N(7)-)-methyltransferase tRNA (guanine-N(7)-)-methyltransferase%3B catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine gene gene355 http://www.ncbi.nlm.nih.gov/gene/?term=HI0340 HI0341 HI0341 HI0341 369038 369382 + hypothetical protein similar to SP:P38521 PID:882488 GB:U00096 PID:1789329 gene gene356 http://www.ncbi.nlm.nih.gov/gene/?term=HI0341 HI0342 HI0342 napF napF 369588 370117 + gene gene357 http://www.ncbi.nlm.nih.gov/gene/?term=HI0342 HI0343 HI0343 napD napD 370110 370391 + nitrate reductase assembly protein NapD similar to SP:P33938 PID:405935 GB:U00096 PID:1788535 gene gene358 http://www.ncbi.nlm.nih.gov/gene/?term=HI0343 HI0344 HI0344 napA napA 370452 372912 + gene gene359 http://www.ncbi.nlm.nih.gov/gene/?term=HI0344 HI0345 HI0345 napG napG 372967 373806 + quinol dehydrogenase periplasmic subunit part of NapHG quinol dehydrogenase%3B couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA%3B secreted by twin arginine translocation pathway gene gene360 http://www.ncbi.nlm.nih.gov/gene/?term=HI0345 HI0346 HI0346 napH napH 373806 374669 + quinol dehydrogenase membrane subunit part of NapHG quinol dehydrogenase%3B couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA gene gene361 http://www.ncbi.nlm.nih.gov/gene/?term=HI0346 HI0347 HI0347 napB napB 374666 375118 + nitrate reductase contains two heme groups%3B similar to SP:P33933 PID:405928 GB:U00096 PID:1788531 gene gene362 http://www.ncbi.nlm.nih.gov/gene/?term=HI0347 HI0348 HI0348 napC napC 375133 375735 + cytochrome C-type protein similar to SP:P33932 PID:405927 GB:U00096 PID:1788530 gene gene363 http://www.ncbi.nlm.nih.gov/gene/?term=HI0348 HI0349 HI0349 adk adk 375895 376539 - adenylate kinase essential enzyme that recycles AMP in active cells%3B converts ATP and AMP to two molecules of ADP gene gene364 http://www.ncbi.nlm.nih.gov/gene/?term=HI0349 HI0350 HI0350 HI0350 376624 377901 - permease similar to GB:U00096 SP:P36670 PID:1773117 PID:1786636 PID:563855 gene gene365 http://www.ncbi.nlm.nih.gov/gene/?term=HI0350 HI0351 HI0351 galE galE 378043 379059 - UDP-glucose 4-epimerase similar to SP:P24325 GB:L42023 PID:1003592 PID:1222277 PID:43589 gene gene366 http://www.ncbi.nlm.nih.gov/gene/?term=HI0351 HI0352 HI0352 HI0352 379232 379927 - hypothetical protein similar to SP:P24324 GB:X57315 PID:43588 gene gene367 http://www.ncbi.nlm.nih.gov/gene/?term=HI0352 HI0354 HI0354 HI0354 380643 381365 + ABC transporter ATP-binding protein similar to PID:1184189 GB:U00096 SP:Q47538 PID:1384059 PID:1657561 gene gene368 http://www.ncbi.nlm.nih.gov/gene/?term=HI0354 HI0355 HI0355 HI0355 381362 382099 + ABC transporter permease similar to GB:L16808 SP:P40401 PID:438473 PID:1903040 GB:AL009126 gene gene369 http://www.ncbi.nlm.nih.gov/gene/?term=HI0355 HI0357 HI0357 HI0357 382121 383065 + thiamine biosynthesis protein similar to SP:P42883 SP:P43534 SP:P47183 PID:1015913 PID:1302455 gene gene370 http://www.ncbi.nlm.nih.gov/gene/?term=HI0357 HI0358 HI0358 HI0358 383075 383722 + transcriptional activator similar to GB:AE000511 PID:2314455 gene gene371 http://www.ncbi.nlm.nih.gov/gene/?term=HI0358 HI0359 HI0359 yfeD yfeD 383822 384637 - iron (chelated) ABC transporter permease similar to PID:1245464 SP:Q56955 PID:1245467 gene gene372 http://www.ncbi.nlm.nih.gov/gene/?term=HI0359 HI0360 HI0360 yfeC yfeC 384630 385478 - iron (chelated) ABC transporter permease similar to PID:1245464 SP:Q56954 PID:1245466 gene gene373 http://www.ncbi.nlm.nih.gov/gene/?term=HI0360 HI0361 HI0361 yfeB yfeB 385482 386402 - iron (chelated) transporter ATP-binding protein similar to PID:1245464 PID:1245465 gene gene374 http://www.ncbi.nlm.nih.gov/gene/?term=HI0361 HI0362 HI0362 yfeA yfeA 386402 387283 - iron-chelated ABC transporter substrate-binding protein similar to PID:1245464 gene gene375 http://www.ncbi.nlm.nih.gov/gene/?term=HI0362 HI0364 HI0364 HI0364 387648 388526 - penicillin-binding protein 7 similar to SP:P33364 GB:X01067 PID:405864 PID:808967 GB:U00096 gene gene376 http://www.ncbi.nlm.nih.gov/gene/?term=HI0364 HI0365 HI0365 HI0365 388752 389924 + ribosomal RNA large subunit methyltransferase N 23S rRNA m2A2503 methyltransferase%3B methylates the C2 position of the A2530 nucleotide in 23S rRNA%3B may be involved in antibiotic resistance gene gene377 http://www.ncbi.nlm.nih.gov/gene/?term=HI0365 HI0366 HI0366 HI0366 390026 390565 + fimbrial biogenesis and twitching motility protein similar to PID:1162960 gene gene378 http://www.ncbi.nlm.nih.gov/gene/?term=HI0366 HI0367 HI0367 HI0367 390637 391548 + hypothetical protein similar to SP:P27434 GB:D21149 GB:U02965 GB:X64451 PID:41541 gene gene379 http://www.ncbi.nlm.nih.gov/gene/?term=HI0367 HI0368 HI0368 ispG ispG 391558 392664 + 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin) catalyzes the conversion of 2C-methyl-D-erythritol 2%2C4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate%3B involved in isoprenoid synthesis gene gene380 http://www.ncbi.nlm.nih.gov/gene/?term=HI0368 HI0369 HI0369 hisS hisS 392674 393945 + histidine--tRNA ligase catalyzes a two-step reaction%2C first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B class II aminoacyl-tRNA synthetase%3B forms homodimers%3B some organisms have a paralogous gene%2C hisZ%2C that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG gene gene381 http://www.ncbi.nlm.nih.gov/gene/?term=HI0369 HI0370 HI0370 HI0370 393962 394576 + hypothetical protein similar to GB:U00096 PID:1788860 gene gene382 http://www.ncbi.nlm.nih.gov/gene/?term=HI0370 HI0371 HI0371 HI0371 394627 394821 - hypothetical protein similar to SP:P37096 GB:U00096 PID:1788873 gene gene383 http://www.ncbi.nlm.nih.gov/gene/?term=HI0371 HI0372 HI0372 fdx-1 fdx-1 394821 395162 - ferredoxin similar to GB:M88654 SP:P25528 PID:145915 GB:U00096 PID:1788874 gene gene384 http://www.ncbi.nlm.nih.gov/gene/?term=HI0372 HI0373 HI0373 hscA hscA 395202 397061 - chaperone protein HscA involved in the maturation of iron-sulfur cluster-containing proteins gene gene385 http://www.ncbi.nlm.nih.gov/gene/?term=HI0373 HI0374 HI0374 HI0374 397080 397766 - hypothetical protein gene gene386 http://www.ncbi.nlm.nih.gov/gene/?term=HI0374 HI0375 HI0375 hscB hscB 397817 398341 - co-chaperone HscB J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone%3B may function in biogenesis of iron-sulfur proteins gene gene387 http://www.ncbi.nlm.nih.gov/gene/?term=HI0375 HI0376 HI0376 HI0376 398354 398677 - hypothetical protein similar to SP:P36539 gene gene388 http://www.ncbi.nlm.nih.gov/gene/?term=HI0376 HI0377 HI0377 iscU iscU 398734 399150 - scaffold protein similar to PID:2271522 gene gene389 http://www.ncbi.nlm.nih.gov/gene/?term=HI0377 HI0378 HI0378 nifS nifS 399174 400388 - cysteine desulfurase catalyzes the removal of elemental sulfur from cysteine to produce alanine%3B involved in NAD biosynthesis gene gene390 http://www.ncbi.nlm.nih.gov/gene/?term=HI0378 HI0379 HI0379 HI0379 400455 400907 - hypothetical protein similar to GB:U00096 PID:1788880 gene gene391 http://www.ncbi.nlm.nih.gov/gene/?term=HI0379 HI0380 HI0380 HI0380 400960 401685 - hypothetical protein similar to GB:U00096 PID:1788881 gene gene392 http://www.ncbi.nlm.nih.gov/gene/?term=HI0380 HI0380.1 HI0380.1 tRNA-Lys-3 tRNA-Lys-3 401796 401871 - tRNA-Lys tRNA gene393 http://www.ncbi.nlm.nih.gov/gene/?term=HI0380.1 HI0380.2 HI0380.2 HI0380.2 401895 401970 - tRNA-Lys tRNA gene394 http://www.ncbi.nlm.nih.gov/gene/?term=HI0380.2 HI0381 HI0381 pal pal 402127 402588 - peptidoglycan-associated outer membrane lipoprotein similar to SP:P10324 PID:1573351 SP:P10324 GB:M18878 PID:1573351 gene gene395 http://www.ncbi.nlm.nih.gov/gene/?term=HI0381 HI0382 HI0382 tolB tolB 402612 403895 - translocation protein TolB forms dimers%3B may be involved in cell envelope integrity%3B interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA gene gene396 http://www.ncbi.nlm.nih.gov/gene/?term=HI0382 HI0383 HI0383 tolA tolA 403937 405055 - cell envelope integrity inner membrane protein TolA inner membrane component of 7 member Tol-Pal envelope-spanning complex%3B involved in maintaining cell envelope integrity%3B utilized by colicins and filamentous phages for import%3B interacts with TolB%2C Pal%2C and through TolB to various outer membrane porins gene gene397 http://www.ncbi.nlm.nih.gov/gene/?term=HI0383 HI0384 HI0384 tolR tolR 405071 405490 - colicin uptake protein TolR membrane spanning protein in TolA-TolQ-TolR complex%3B involved in the tonB-independent uptake of group A colicins gene gene398 http://www.ncbi.nlm.nih.gov/gene/?term=HI0384 HI0385 HI0385 tolQ tolQ 405562 406248 - colicin transport protein similar to SP:P05828 PID:1128978 GB:U00096 PID:1651329 PID:1786958 gene gene399 http://www.ncbi.nlm.nih.gov/gene/?term=HI0385 HI0386 HI0386 HI0386 406265 406675 - acyl-CoA thioesterase YbgC similar to SP:P08999 PID:1128977 GB:U00096 PID:1786957 gene gene400 http://www.ncbi.nlm.nih.gov/gene/?term=HI0386 HI0387 HI0387 dinG dinG 407000 408922 + ATP-dependent helicase similar to GB:U00096 PID:1736441 PID:1736447 PID:1788110 gene gene401 http://www.ncbi.nlm.nih.gov/gene/?term=HI0387 HI0388 HI0388 HI0388 408935 409645 + hypothetical protein similar to GB:U00096 SP:P76256 PID:1736440 PID:1736446 PID:1788109 gene gene402 http://www.ncbi.nlm.nih.gov/gene/?term=HI0388 HI0389 HI0389 HI0389 409670 410221 + outer membrane protein similar to GB:U00039 SP:P37194 GB:L23635 PID:387932 PID:466643 gene gene403 http://www.ncbi.nlm.nih.gov/gene/?term=HI0389 HI0390 HI0390 rnd rnd 411952 413151 + ribonuclease D similar to SP:P09155 GB:X07055 GB:X70994 PID:581071 PID:581215 gene gene405 http://www.ncbi.nlm.nih.gov/gene/?term=HI0390 HI0390.1 HI0390.1 fadD fadD 410264 411952 + long-chain-fatty-acid--CoA ligase Activates fatty acids by binding to coenzyme A gene gene404 http://www.ncbi.nlm.nih.gov/gene/?term=HI0390.1 HI0391 HI0391 HI0391 413194 414968 - gene gene406 http://www.ncbi.nlm.nih.gov/gene/?term=HI0391 HI0393 HI0393 ychF ychF 415151 416242 - GTP-dependent nucleic acid-binding protein EngD translation-associated GTPase%3B the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3)%3B fluorescence spectroscopy revealed nucleic acid binding%3B the yeast protein YBR025c interacts with the translation elongation factor eEF1 gene gene407 http://www.ncbi.nlm.nih.gov/gene/?term=HI0393 HI0394 HI0394 pth pth 416291 416875 - peptidyl-tRNA hydrolase Enables the recycling of peptidyl-tRNAs produced at termination of translation gene gene408 http://www.ncbi.nlm.nih.gov/gene/?term=HI0394 HI0395 HI0395 HI0395 417042 417350 + hypothetical protein similar to PID:1033114 SP:P52119 GB:U00096 PID:1788971 gene gene409 http://www.ncbi.nlm.nih.gov/gene/?term=HI0395 HI0396 HI0396 HI0396 417353 418567 + hypothetical protein similar to SP:P27431 GB:U00096 PID:1787373 gene gene410 http://www.ncbi.nlm.nih.gov/gene/?term=HI0396 HI0397 HI0397 xseA xseA 418569 419888 + exodeoxyribonuclease VII large subunit bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides gene gene411 http://www.ncbi.nlm.nih.gov/gene/?term=HI0397 HI0398 HI0398 HI0398 420086 420718 + hypothetical protein similar to SP:P36651 PID:882564 GB:U00096 PID:1789412 gene gene412 http://www.ncbi.nlm.nih.gov/gene/?term=HI0398 HI0399 HI0399 icc icc 420728 421552 + cyclic 3'%2C5'-adenosine monophosphate phosphodiesterase similar to GB:D16557 SP:P36650 PID:453396 PID:882562 GB:U00096 gene gene413 http://www.ncbi.nlm.nih.gov/gene/?term=HI0399 HI0400 HI0400 HI0400 421650 421937 - hypothetical protein similar to GB:U00096 PID:1788685 gene gene414 http://www.ncbi.nlm.nih.gov/gene/?term=HI0400 HI0401 HI0401 fadL fadL 422144 423523 + long-chain fatty acid transport protein similar to GB:M60607 SP:P10384 GB:Y00552 PID:145910 PID:41372 gene gene415 http://www.ncbi.nlm.nih.gov/gene/?term=HI0401 HI0402 HI0402 HI0402 423567 424139 + methylated-DNA-protein-cysteine methyltransferase dat1%3B similar to SP:P11742 GB:X15659 PID:39876 GB:AL009126 gene gene416 http://www.ncbi.nlm.nih.gov/gene/?term=HI0402 HI0403 HI0403 mutH mutH 424136 424807 + DNA mismatch repair protein MutH%3B Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair gene gene417 http://www.ncbi.nlm.nih.gov/gene/?term=HI0403 HI0404 HI0404 mesJ mesJ 424804 426096 - cell cycle protein similar to GB:U00096 PID:1552765 PID:1786386 PID:971394 gene gene418 http://www.ncbi.nlm.nih.gov/gene/?term=HI0404 HI0405 HI0405 HI0405 426096 426962 - pyridoxamine kinase catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal gene gene419 http://www.ncbi.nlm.nih.gov/gene/?term=HI0405 HI0406 HI0406 accA accA 427035 427982 - acetyl-CoA carboxylase carboxyltransferase subunit alpha catalyzes the carboxylation of acetyl-CoA to malonyl-CoA%3B forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits%3B one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein gene gene420 http://www.ncbi.nlm.nih.gov/gene/?term=HI0406 HI0407 HI0407 HI0407 428072 428857 - hypothetical protein similar to PID:1054959 GB:U00096 PID:1788166 gene gene421 http://www.ncbi.nlm.nih.gov/gene/?term=HI0407 HI0408 HI0408 yebM yebM 428857 429663 - ABC transporter ATP-binding protein similar to SP:P52648 GB:U00096 PID:1736501 PID:1736505 PID:1788165 gene gene422 http://www.ncbi.nlm.nih.gov/gene/?term=HI0408 HI0409 HI0409 HI0409 429835 431262 + hypothetical protein similar to GB:M77039 SP:P24204 PID:146890 PID:1054957 GB:U00096 gene gene423 http://www.ncbi.nlm.nih.gov/gene/?term=HI0409 HI0410 HI0410 tyrR tyrR 431377 432333 + transcriptional regulatory protein contains a C-terminal HTH DNA-binding domain%3B similar to GB:M12114 SP:P07604 PID:148092 GB:U00096 PID:1742168 gene gene424 http://www.ncbi.nlm.nih.gov/gene/?term=HI0410 HI0411 HI0411 hfq hfq 432430 432705 - RNA-binding protein Hfq Stimulates the elongation of poly(A) tails gene gene425 http://www.ncbi.nlm.nih.gov/gene/?term=HI0411 HI0412 HI0412 HI0412 432796 433764 - 23S rRNA pseudouridylate synthase C catalyzes the transformation of uracil to pseudouracil at nucleotides U955%2C U2504%2C and U2580 in 23S rRNA gene gene426 http://www.ncbi.nlm.nih.gov/gene/?term=HI0412 HI0413 HI0413 rne rne 434185 436992 + ribonuclease E similar to SP:P21513 GB:X67470 GB:L23942 GB:M62747 GB:X54309 gene gene427 http://www.ncbi.nlm.nih.gov/gene/?term=HI0413 HI0414 HI0414 HI0414 437224 437436 + hypothetical protein gene gene428 http://www.ncbi.nlm.nih.gov/gene/?term=HI0414 HI0415 HI0415 HI0415 437760 438557 + hydroxyethylthiazole kinase catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP gene gene429 http://www.ncbi.nlm.nih.gov/gene/?term=HI0415 HI0416 HI0416 thiD thiD 438550 439359 + phosphomethylpyrimidine kinase catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine gene gene430 http://www.ncbi.nlm.nih.gov/gene/?term=HI0416 HI0417 HI0417 thiE thiE 439370 440050 + thiamine-phosphate pyrophosphorylase Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate gene gene431 http://www.ncbi.nlm.nih.gov/gene/?term=HI0417 HI0418 HI0418 HI0418 439995 441338 + transporter similar to GB:L42023 SP:P44610 PID:1003458 PID:1222206 PID:1204537 gene gene432 http://www.ncbi.nlm.nih.gov/gene/?term=HI0418 HI0419 HI0419 HI0419 441507 442889 + protease similar to GB:U00096 SP:P76403 PID:1736789 PID:1736801 PID:1788397 gene gene433 http://www.ncbi.nlm.nih.gov/gene/?term=HI0419 HI0420 HI0420 HI0420 443031 443330 + hypothetical protein gene gene434 http://www.ncbi.nlm.nih.gov/gene/?term=HI0420 HI0420.1 HI0420.1 HI0420.1 443273 443943 + gene gene435 http://www.ncbi.nlm.nih.gov/gene/?term=HI0420.1 HI0422 HI0422 srmB srmB 444029 445348 - ATP-dependent RNA helicase SrmB facilitates an early step in the assembly of the 50S subunit of the ribosome gene gene436 http://www.ncbi.nlm.nih.gov/gene/?term=HI0422 HI0423 HI0423 HI0423 445394 446116 + hypothetical protein similar to SP:P31825 GB:U00096 PID:1788929 gene gene437 http://www.ncbi.nlm.nih.gov/gene/?term=HI0423 HI0424 HI0424 HI0424 446149 447204 - rRNA methylase similar to SP:P33635 GB:U00096 PID:1788935 gene gene438 http://www.ncbi.nlm.nih.gov/gene/?term=HI0424 HI0425 HI0425 pssA pssA 447351 448718 + phosphatidylserine synthase catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine%3B bounds to the ribosome gene gene439 http://www.ncbi.nlm.nih.gov/gene/?term=HI0425 HI0426 HI0426 fadR fadR 448763 449488 - fatty acid metabolism regulator Multifunctional regulator of fatty acid metabolism gene gene440 http://www.ncbi.nlm.nih.gov/gene/?term=HI0426 HI0427 HI0427 nhaB nhaB 449613 451157 + sodium/proton antiporter involved in regulation of intracellular pH under alkaline conditions gene gene441 http://www.ncbi.nlm.nih.gov/gene/?term=HI0427 HI0428 HI0428 dsbB dsbB 451167 451700 + disulfide bond formation protein B disulfide oxidoreductase%3B integral membrane protein%3B required for perioplasmic disulfide bond formation%3B oxidizes DsbA protein gene gene442 http://www.ncbi.nlm.nih.gov/gene/?term=HI0428 HI0429 HI0429 glmS glmS 451754 453586 - glucosamine--fructose-6-phosphate aminotransferase Catalyzes the first step in hexosamine metabolism%2C converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source gene gene443 http://www.ncbi.nlm.nih.gov/gene/?term=HI0429 HI0430 HI0430 HI0430 453698 453970 - DNA-binding protein HU-alpha similar to SP:P02342 GB:D12624 GB:X05994 PID:216565 PID:396339 gene gene444 http://www.ncbi.nlm.nih.gov/gene/?term=HI0430 HI0431 HI0431 HI0431 454110 454700 - hypothetical protein similar to SP:P32680 PID:396338 GB:U00096 PID:1790432 gene gene445 http://www.ncbi.nlm.nih.gov/gene/?term=HI0431 HI0432 HI0432 nudC nudC 454736 455530 - NADH pyrophosphatase can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH%3B requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates gene gene446 http://www.ncbi.nlm.nih.gov/gene/?term=HI0432 HI0433 HI0433 HI0433 455597 456193 - DNA uptake protein cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source gene gene447 http://www.ncbi.nlm.nih.gov/gene/?term=HI0433 HI0434 HI0434 comF comF 456269 456958 - competence protein F similar to GB:M59751 SP:P31773 PID:1573409 gene gene448 http://www.ncbi.nlm.nih.gov/gene/?term=HI0434 HI0435 HI0435 comE comE 456967 458304 - competence protein E similar to GB:M62809 SP:P31772 PID:1573410 gene gene449 http://www.ncbi.nlm.nih.gov/gene/?term=HI0435 HI0436 HI0436 comD comD 458314 458727 - competence protein D similar to GB:M62809 SP:P31771 PID:1573411 gene gene450 http://www.ncbi.nlm.nih.gov/gene/?term=HI0436 HI0437 HI0437 comC comC 458724 459245 - competence protein C similar to GB:M62809 SP:P31770 PID:1573412 gene gene451 http://www.ncbi.nlm.nih.gov/gene/?term=HI0437 HI0438 HI0438 comB comB 459242 459748 - competence protein B similar to GB:M62809 SP:P31769 PID:1573413 gene gene452 http://www.ncbi.nlm.nih.gov/gene/?term=HI0438 HI0439 HI0439 comA comA 459749 460546 - competence protein A similar to GB:M62809 SP:P31768 PID:1573414 gene gene453 http://www.ncbi.nlm.nih.gov/gene/?term=HI0439 HI0440 HI0440 ponA ponA 460645 463239 + penicillin-binding protein 1A similar to SP:P02918 GB:X02164 PID:581194 PID:606330 GB:U00096 gene gene454 http://www.ncbi.nlm.nih.gov/gene/?term=HI0440 HI0441 HI0441 HI0441 463327 464172 + hypothetical protein OrfJ%3B similar to GB:M62809 SP:P31777 PID:1573417 gene gene455 http://www.ncbi.nlm.nih.gov/gene/?term=HI0441 HI0442 HI0442 ybaB ybaB 464325 464654 + hypothetical protein forms homodimers%3B coexpressed with recR%3B similar to GB:M38777 SP:P17577 GB:X04487 PID:145298 PID:43322 gene gene456 http://www.ncbi.nlm.nih.gov/gene/?term=HI0442 HI0443 HI0443 recR recR 464716 465318 + recombination protein RecR involved in a recombinational process of DNA repair%2C independent of the recBC complex gene gene457 http://www.ncbi.nlm.nih.gov/gene/?term=HI0443 HI0444 HI0444 topB topB 465334 467289 + DNA topoisomerase III decatenates replicating daughter chromosomes gene gene458 http://www.ncbi.nlm.nih.gov/gene/?term=HI0444 HI0445 HI0445 secG secG 467398 467736 + preprotein translocase subunit SecG similar to GB:D16463 SP:P33582 GB:U01376 PID:431135 PID:606113 gene gene459 http://www.ncbi.nlm.nih.gov/gene/?term=HI0445 HI0445.1 HI0445.1 tRNA-Leu-3 tRNA-Leu-3 467760 467842 + tRNA-Leu tRNA gene460 http://www.ncbi.nlm.nih.gov/gene/?term=HI0445.1 HI0446 HI0446 fruA fruA 468265 469935 - PTS system fructose-specific transporter subunit IIBC similar to SP:P20966 GB:M23196 PID:405893 PID:450372 GB:U00096 gene gene461 http://www.ncbi.nlm.nih.gov/gene/?term=HI0446 HI0447 HI0447 fruK fruK 469937 470878 - 1-phosphofructokinase converts fructose-1-phosphate and ATP to fructose-1%2C6-bisphosphate and ADP%3B highly specific for fructose-1-phopshate%3B similar to PfkB%3B forms homodimers gene gene462 http://www.ncbi.nlm.nih.gov/gene/?term=HI0447 HI0448 HI0448 fruB fruB 470880 472379 - PTS system fructose-specific transporter subunit IIA/HPr protein phosphoenolpyruvate (PEP)-dependent%2C sugar transporting phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr gene gene463 http://www.ncbi.nlm.nih.gov/gene/?term=HI0448 HI0449 HI0449 HI0449 472451 472987 - hypothetical protein gene gene464 http://www.ncbi.nlm.nih.gov/gene/?term=HI0449 HI0450 HI0450 vapD vapD 473074 473349 - virulence-associated protein D similar to GB:L22307 GB:L31763 GB:M74565 PID:145067 PID:438533 gene gene465 http://www.ncbi.nlm.nih.gov/gene/?term=HI0450 HI0451 HI0451 HI0451 473358 473549 - hypothetical protein similar to PID:1196479 gene gene466 http://www.ncbi.nlm.nih.gov/gene/?term=HI0451 HI0452 HI0452 HI0452 473621 474919 - hypothetical protein similar to GB:U14003 SP:P39319 PID:537059 GB:U00096 PID:1790664 gene gene467 http://www.ncbi.nlm.nih.gov/gene/?term=HI0452 HI0453 HI0453 HI0453 474970 475494 - hypothetical protein similar to GB:AE000511 PID:2313105 gene gene468 http://www.ncbi.nlm.nih.gov/gene/?term=HI0453 HI0454 HI0454 HI0454 475521 476303 - hypothetical protein similar to SP:P37346 GB:U00096 PID:1787342 gene gene469 http://www.ncbi.nlm.nih.gov/gene/?term=HI0454 HI0455 HI0455 holB holB 476358 477341 - DNA polymerase III subunit delta' catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand%3B the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA gene gene470 http://www.ncbi.nlm.nih.gov/gene/?term=HI0455 HI0456 HI0456 tmk tmk 477338 477997 - thymidylate kinase catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) gene gene471 http://www.ncbi.nlm.nih.gov/gene/?term=HI0456 HI0457 HI0457 HI0457 477987 479030 - hypothetical protein similar to GB:U00096 PID:1510185 PID:1787339 gene gene472 http://www.ncbi.nlm.nih.gov/gene/?term=HI0457 HI0458 HI0458 HI0458 479100 480041 - stationary-phase survival protein SurA similar to SP:P21202 GB:M68521 PID:147119 PID:216478 GB:U00096 gene gene473 http://www.ncbi.nlm.nih.gov/gene/?term=HI0458 HI0459 HI0459 pyrR pyrR 480112 480651 - bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes%2C also has been shown to have uracil phosphoribosyltransferase activity gene gene474 http://www.ncbi.nlm.nih.gov/gene/?term=HI0459 HI0460 HI0460 mazG mazG 480783 481574 + nucleoside triphosphate pyrophosphohydrolase functions in degradation of stringent response intracellular messenger ppGpp%3B in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF%3B activity of MazG is inhibited by MazEF in vitro%3B ppGpp inhibits mazEF expression%3B MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation%3B MazG also interacts with the GTPase protein Era gene gene475 http://www.ncbi.nlm.nih.gov/gene/?term=HI0460 HI0461 HI0461 HI0461 481624 482499 - hypothetical protein similar to SP:P32181 gene gene476 http://www.ncbi.nlm.nih.gov/gene/?term=HI0461 HI0462 HI0462 lon lon 482692 485103 + ATP-dependent proteinase similar to GB:M38347 SP:P08177 GB:J03896 GB:L12349 GB:L20572 gene gene477 http://www.ncbi.nlm.nih.gov/gene/?term=HI0462 HI0463 HI0463 HI0463 485219 486370 + coproporphyrinogen III oxidase catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III gene gene478 http://www.ncbi.nlm.nih.gov/gene/?term=HI0463 HI0464 HI0464 rpiA rpiA 486503 487162 + ribose-5-phosphate isomerase A Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway gene gene479 http://www.ncbi.nlm.nih.gov/gene/?term=HI0464 HI0465 HI0465 serA serA 487192 488424 + D-3-phosphoglycerate dehydrogenase catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis%3B can also reduce alpha ketoglutarate to form 2-hydroxyglutarate gene gene480 http://www.ncbi.nlm.nih.gov/gene/?term=HI0465 HI0466 HI0466 HI0466 488468 489310 - hypothetical protein similar to PID:887848 GB:U00096 SP:P39179 PID:1789265 gene gene481 http://www.ncbi.nlm.nih.gov/gene/?term=HI0466 HI0467 HI0467 HI0467 489320 490183 - hypothetical protein similar to GB:L10328 SP:P23839 GB:X14235 PID:290494 PID:42721 gene gene482 http://www.ncbi.nlm.nih.gov/gene/?term=HI0467 HI0468 HI0468 hisG hisG 490631 491542 + ATP phosphoribosyltransferase long form of enzyme%3B catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate%3B crucial role in histidine biosynthesis%3B forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors gene gene483 http://www.ncbi.nlm.nih.gov/gene/?term=HI0468 HI0469 HI0469 hisD hisD 491635 492918 + histidinol dehydrogenase catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis%3B functions as a dimer gene gene484 http://www.ncbi.nlm.nih.gov/gene/?term=HI0469 HI0470 HI0470 hisC hisC 492987 494090 + histidinol-phosphate aminotransferase catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis gene gene485 http://www.ncbi.nlm.nih.gov/gene/?term=HI0470 HI0471 HI0471 hisB hisB 494202 495290 + imidazole glycerol-phosphate dehydratase/histidinol phosphatase catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate gene gene486 http://www.ncbi.nlm.nih.gov/gene/?term=HI0471 HI0472 HI0472 hisH hisH 495356 495955 + imidazole glycerol phosphate synthase subunit HisH with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate%2C 5-aminoimidazol-4-carboxamide ribonucleotide%2C and glutamate in histidine biosynthesis%3B the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide gene gene487 http://www.ncbi.nlm.nih.gov/gene/?term=HI0472 HI0473 HI0473 hisA hisA 495991 496740 + 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l-(5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide gene gene488 http://www.ncbi.nlm.nih.gov/gene/?term=HI0473 HI0474 HI0474 hisF hisF 496722 497498 + imidazole glycerol phosphate synthase subunit HisF catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]-1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate%2C 5-aminoimidazol-4-carboxamideribonucleotide and glutamate%3B the HisF subunit acts as a cyclase gene gene489 http://www.ncbi.nlm.nih.gov/gene/?term=HI0474 HI0475 HI0475 hisIE hisIE 497498 498163 + bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis gene gene490 http://www.ncbi.nlm.nih.gov/gene/?term=HI0475 HI0477 HI0477 tyrP tyrP 498427 499629 + tyrosine-specific transport protein similar to GB:M23240 SP:P18199 PID:148089 GB:U00096 PID:1736569 gene gene491 http://www.ncbi.nlm.nih.gov/gene/?term=HI0477 HI0478 HI0478 atpC atpC 499815 500243 - F0F1 ATP synthase subunit epsilon part of catalytic core of ATP synthase%3B alpha(3)beta(3)gamma(1)delta(1)epsilon(1)%3B involved in producing ATP from ADP in the presence of the proton motive force across the membrane gene gene492 http://www.ncbi.nlm.nih.gov/gene/?term=HI0478 HI0479 HI0479 atpD atpD 500273 501646 - F0F1 ATP synthase subunit beta Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit gene gene493 http://www.ncbi.nlm.nih.gov/gene/?term=HI0479 HI0480 HI0480 atpG atpG 501663 502532 - F0F1 ATP synthase subunit gamma Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit gene gene494 http://www.ncbi.nlm.nih.gov/gene/?term=HI0480 HI0481 HI0481 atpA atpA 502548 504089 - F0F1 ATP synthase subunit alpha produces ATP from ADP in the presence of a proton gradient across the membrane%3B the alpha chain is a catalytic subunit gene gene495 http://www.ncbi.nlm.nih.gov/gene/?term=HI0481 HI0482 HI0482 atpH atpH 504102 504635 - F0F1 ATP synthase subunit delta Produces ATP from ADP in the presence of a proton gradient across the membrane%3B the delta subunit is part of the catalytic core of the ATP synthase complex gene gene496 http://www.ncbi.nlm.nih.gov/gene/?term=HI0482 HI0483 HI0483 atpF atpF 504648 505118 - F0F1 ATP synthase subunit B Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. gene gene497 http://www.ncbi.nlm.nih.gov/gene/?term=HI0483 HI0484 HI0484 atpE atpE 505168 505422 - F0F1 ATP synthase subunit C Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 gene gene498 http://www.ncbi.nlm.nih.gov/gene/?term=HI0484 HI0485 HI0485 atpB atpB 505478 506266 - F0F1 ATP synthase subunit A Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 gene gene499 http://www.ncbi.nlm.nih.gov/gene/?term=HI0485 HI0485.1 HI0485.1 HI0485.1 506303 506677 - F0F1 ATP synthase subunit I Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation gene gene500 http://www.ncbi.nlm.nih.gov/gene/?term=HI0485.1 HI0486 HI0486 gidB gidB 506803 507414 - 16S rRNA methyltransferase GidB glucose-inhibited division protein B%3B SAM-dependent methyltransferase%3B methylates the N7 position of guanosine in position 527 of 16S rRNA gene gene501 http://www.ncbi.nlm.nih.gov/gene/?term=HI0486 HI0487 HI0487 HI0487 507554 507931 - hypothetical protein gene gene502 http://www.ncbi.nlm.nih.gov/gene/?term=HI0487 HI0488 HI0488 HI0488 508047 508649 + phosphatase/phosphohexomutase similar to GB:U00096 PID:1789046 gene gene503 http://www.ncbi.nlm.nih.gov/gene/?term=HI0488 HI0489 HI0489 HI0489 508649 509122 + hypothetical protein similar to GB:U00096 PID:1789045 gene gene504 http://www.ncbi.nlm.nih.gov/gene/?term=HI0489 HI0491 HI0491 luxS luxS 509452 509955 + S-ribosylhomocysteinase catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2 gene gene505 http://www.ncbi.nlm.nih.gov/gene/?term=HI0491 HI0493 HI0493 HI0493 510454 510810 + hypothetical protein similar to GB:M29945 PID:1197032 gene gene506 http://www.ncbi.nlm.nih.gov/gene/?term=HI0493 HI0495m HI0495m aphA aphA 510901 511609 - acid phosphatase/phosphotransferase Class B%3B non-specific%3B catalyzes the dephosphorylation of organic phosphomonoesters%3B also has phosphotransferase activity gene gene507 http://www.ncbi.nlm.nih.gov/gene/?term=HI0495m HI0496 HI0496 hslV hslV 511828 512355 + ATP-dependent protease peptidase subunit heat shock protein involved in degradation of misfolded proteins gene gene508 http://www.ncbi.nlm.nih.gov/gene/?term=HI0496 HI0497 HI0497 hslU hslU 512366 513700 + ATP-dependent protease ATP-binding subunit HslU heat shock protein involved in degradation of misfolded proteins gene gene509 http://www.ncbi.nlm.nih.gov/gene/?term=HI0497 HI0498 HI0498 potD potD 513770 514822 - spermidine/putrescine ABC transporter substrate-binding protein similar to GB:M64519 SP:P23861 PID:147329 GB:U00096 PID:1651550 gene gene510 http://www.ncbi.nlm.nih.gov/gene/?term=HI0498 HI0499 HI0499 HI0499 514963 516258 + oxidoreductase similar to GB:M38433 SP:P37906 PID:1054921 PID:551780 GB:U00096 gene gene511 http://www.ncbi.nlm.nih.gov/gene/?term=HI0499 HI0500 HI0500 HI0500 516703 517866 + hypothetical protein similar to GB:M87049 SP:P27850 PID:148230 GB:U00096 PID:1790266 gene gene512 http://www.ncbi.nlm.nih.gov/gene/?term=HI0500 HI0501 HI0501 rbsD rbsD 518034 518453 + D-ribose pyranase cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose%3B RbsD is required for efficient ribose utilization in E. coli%3B rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source gene gene513 http://www.ncbi.nlm.nih.gov/gene/?term=HI0501 HI0502 HI0502 rbsA rbsA 518467 519948 + D-ribose transporter ATP binding protein with RbsBCD acts to import ribose into the cell%3B RbsA contains 2 ATP-binding domain gene gene514 http://www.ncbi.nlm.nih.gov/gene/?term=HI0502 HI0503 HI0503 rbsC rbsC 519961 520932 + ribose ABC transporter permease functions to transport ribose at high affinity%3B forms a complex with RbsA2C2B gene gene515 http://www.ncbi.nlm.nih.gov/gene/?term=HI0503 HI0504 HI0504 rbsB rbsB 520952 521830 + D-ribose transporter subunit RbsB periplasmic substrate-binding component of the ATP-dependent ribose transport system gene gene516 http://www.ncbi.nlm.nih.gov/gene/?term=HI0504 HI0505 HI0505 rbsK rbsK 521928 522848 + ribokinase catalyzes the formation of D-ribose 5-phosphate from ribose gene gene517 http://www.ncbi.nlm.nih.gov/gene/?term=HI0505 HI0506 HI0506 rbsR rbsR 522876 523874 + RBS repressor similar to GB:L10328 SP:P25551 GB:D10466 GB:M13169 PID:147517 gene gene518 http://www.ncbi.nlm.nih.gov/gene/?term=HI0506 HI0507 HI0507 HI0507 523980 524531 + hypothetical protein similar to PID:882531 SP:P52082 GB:U00096 PID:1789376 gene gene519 http://www.ncbi.nlm.nih.gov/gene/?term=HI0507 HI0508 HI0508 menG menG 524671 525159 - ribonuclease activity regulator protein RraA regulator of RNase E%3B increases half-life and abundance of RNAs%3B interacts with RNase E possibly inhibiting catalytic activity gene gene520 http://www.ncbi.nlm.nih.gov/gene/?term=HI0508 HI0509 HI0509 menA menA 525211 526122 - 1%2C4-dihydroxy-2-naphthoate octaprenyltransferase catalyzes the formation of dimethylmenaquinone from 1%2C4-dihydroxy-2-naphthoate and octaprenyl diphosphate gene gene521 http://www.ncbi.nlm.nih.gov/gene/?term=HI0509 HI0510 HI0510 HI0510 526184 526903 + hypothetical protein similar to GB:D15061 SP:P28634 PID:303558 GB:U00096 PID:1552771 gene gene522 http://www.ncbi.nlm.nih.gov/gene/?term=HI0510 HI0511 HI0511 HI0511 526956 527942 - potassium-tellurite ethidium and proflavin transporter similar to GB:M74072 SP:P25396 PID:149017 GB:U00096 PID:1742325 gene gene523 http://www.ncbi.nlm.nih.gov/gene/?term=HI0511 HI0512 HI0512 hindIIR hindIIR 528159 528935 - type II restriction endonuclease HincIIR%3B HindIIR%3B binds gtyrac palindromes as a dimer%3B similar to GB:X52124 SP:P17743 PID:1573497 gene gene524 http://www.ncbi.nlm.nih.gov/gene/?term=HI0512 HI0513 HI0513 hindIIM hindIIM 528932 530488 - modification methylase similar to SP:P17744 gene gene525 http://www.ncbi.nlm.nih.gov/gene/?term=HI0513 HI0514 HI0514 rpoC rpoC 530561 534808 - DNA-directed RNA polymerase subunit beta' DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter gene gene526 http://www.ncbi.nlm.nih.gov/gene/?term=HI0514 HI0515 HI0515 rpoB rpoB 535050 539081 - DNA-directed RNA polymerase subunit beta DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates%3B beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme gene gene527 http://www.ncbi.nlm.nih.gov/gene/?term=HI0515 HI0516 HI0516 rplA rplA 539465 540154 - 50S ribosomal protein L1 in Escherichia coli and Methanococcus%2C this protein autoregulates expression%3B the binding site in the mRNA mimics the binding site in the 23S rRNA gene gene528 http://www.ncbi.nlm.nih.gov/gene/?term=HI0516 HI0517 HI0517 rplK rplK 540159 540587 - 50S ribosomal protein L11 binds directly to 23S ribosomal RNA gene gene529 http://www.ncbi.nlm.nih.gov/gene/?term=HI0517 HI0518 HI0518 deoD deoD 540760 541476 - purine nucleoside phosphorylase catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate gene gene530 http://www.ncbi.nlm.nih.gov/gene/?term=HI0518 HI0519 HI0519 HI0519 541560 542813 - transporter similar to GB:AE000511 PID:2314337 gene gene531 http://www.ncbi.nlm.nih.gov/gene/?term=HI0519 HI0520 HI0520 HI0520 542912 543700 - hypothetical protein similar to GB:U14003 SP:P39409 PID:537219 GB:U00096 PID:1790839 gene gene532 http://www.ncbi.nlm.nih.gov/gene/?term=HI0520 HI0521 HI0521 HI0521 543709 545253 - hypothetical protein similar to GB:U14003 SP:P37342 PID:537220 GB:U00096 PID:1790840 gene gene533 http://www.ncbi.nlm.nih.gov/gene/?term=HI0521 HI0522 HI0522 HI0522 545466 546122 + hypothetical protein similar to GB:D26185 SP:P37505 PID:467358 GB:AL009126 gene gene534 http://www.ncbi.nlm.nih.gov/gene/?term=HI0522 HI0523 HI0523 HI0523 546078 547118 - heptosyltransferase-like protein similar to GB:AE000511 PID:2314449 gene gene535 http://www.ncbi.nlm.nih.gov/gene/?term=HI0523 HI0524 HI0524 fba fba 547186 548265 - fructose-bisphosphate aldolase catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1%2C6%2C bisphosphate gene gene536 http://www.ncbi.nlm.nih.gov/gene/?term=HI0524 HI0525 HI0525 pgk pgk 548376 549536 - phosphoglycerate kinase Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway gene gene537 http://www.ncbi.nlm.nih.gov/gene/?term=HI0525 HI0526 HI0526 HI0526 549638 550456 - hypothetical protein gene gene538 http://www.ncbi.nlm.nih.gov/gene/?term=HI0526 HI0527 HI0527 fdx-2 fdx-2 550534 550794 + ferredoxin similar to SP:P00208 gene gene539 http://www.ncbi.nlm.nih.gov/gene/?term=HI0527 HI0528 HI0528 tyrP tyrP 550936 552156 - tyrosine-specific transport protein similar to GB:M23240 SP:P18199 PID:148089 GB:U00096 PID:1736569 gene gene540 http://www.ncbi.nlm.nih.gov/gene/?term=HI0528 HI0529 HI0529 tdk tdk 552193 552744 - thymidine kinase catalyzes the formation of thymidine 5'-phosphate from thymidine gene gene541 http://www.ncbi.nlm.nih.gov/gene/?term=HI0529 HI0530 HI0530 gcp gcp 552783 553811 - DNA-binding/iron metalloprotein/AP endonuclease in most organisms%2C only the N-terminal domain is present in a single polypeptide%3B in some archaea this domain is fused to a kinase domain%3B this gene is essential for growth in Escherichia coli and Bacillus subtilis%3B the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins%3B the Pyrococcus structure shows DNA-binding properties%2C iron-binding%2C ATP-binding%2C and AP endonuclease activity gene gene542 http://www.ncbi.nlm.nih.gov/gene/?term=HI0530 HI0531 HI0531 rpsU rpsU 554043 554258 + 30S ribosomal protein S21 a small basic protein that is one of the last in the subunit assembly%3B omission does not prevent assembly but the subunit is inactive%3B binds central domain of 16S rRNA gene gene543 http://www.ncbi.nlm.nih.gov/gene/?term=HI0531 HI0532 HI0532 dnaG dnaG 554392 556173 + DNA primase synthesizes RNA primers at the replication forks gene gene544 http://www.ncbi.nlm.nih.gov/gene/?term=HI0532 HI0533 HI0533 rpoD rpoD 556243 558132 + RNA polymerase sigma-70 factor similar to GB:J01687 SP:P00579 PID:147756 PID:882590 PID:1072030 gene gene545 http://www.ncbi.nlm.nih.gov/gene/?term=HI0533 HI0534 HI0534 aspA aspA 558436 559863 - aspartate ammonia-lyase catalyzes the formation of fumarate from aspartate gene gene546 http://www.ncbi.nlm.nih.gov/gene/?term=HI0534 HI0535 HI0535 ureH ureH 560041 560826 - urease accessory protein similar to GB:M84338 SP:Q09067 PID:485336 PID:1247672 GB:AE000511 gene gene547 http://www.ncbi.nlm.nih.gov/gene/?term=HI0535 HI0536 HI0536 ureG ureG 560901 561578 - urease accessory protein similar to GB:M84338 SP:Q09066 PID:485335 PID:1247672 GB:AE000511 gene gene548 http://www.ncbi.nlm.nih.gov/gene/?term=HI0536 HI0537 HI0537 ureF ureF 561681 562388 - urease accessory protein UreF similar to SP:Q07402 PID:393298 gene gene549 http://www.ncbi.nlm.nih.gov/gene/?term=HI0537 HI0538 HI0538 ureE ureE 562373 562930 - urease accessory protein UreE involved in the assembly of the urease metallocenter%3B possible nickel donor gene gene550 http://www.ncbi.nlm.nih.gov/gene/?term=HI0538 HI0539 HI0539 ureC ureC 563058 564776 - urease subunit alpha ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide%3B in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa%3B the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits gene gene551 http://www.ncbi.nlm.nih.gov/gene/?term=HI0539 HI0540 HI0540 ureB ureB 564788 565093 - urease subunit beta ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide%3B in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa%3B the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta)%3B in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity%2C optimum growth%2C resistance to low-pH killing in-vitro and persistence in-vivo%2C while the other operon does not seem to be active gene gene552 http://www.ncbi.nlm.nih.gov/gene/?term=HI0540 HI0541 HI0541 ureA ureA 565169 565471 - urease subunit gamma UreA%2C with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide%3B nickel metalloenzyme%3B accessory proteins UreD%2C UreE%2C UreF%2C and UreG are necessary for assembly of the metallocenter gene gene553 http://www.ncbi.nlm.nih.gov/gene/?term=HI0541 HI0542 HI0542 groES groES 565634 565924 + co-chaperonin GroES 10 kDa chaperonin%3B Cpn10%3B GroES%3B forms homoheptameric ring%3B binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it%3B folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES%3B release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring gene gene554 http://www.ncbi.nlm.nih.gov/gene/?term=HI0542 HI0543 HI0543 groEL groEL 565947 567593 + chaperonin GroEL 60 kDa chaperone family%3B promotes refolding of misfolded polypeptides especially under stressful conditions%3B forms two stacked rings of heptamers to form a barrel-shaped 14mer%3B ends can be capped by GroES%3B misfolded proteins enter the barrel where they are refolded when GroES binds%3B many bacteria have multiple copies of the groEL gene which are active under different environmental conditions%3B the B.japonicum protein in this cluster is expressed constitutively%3B in Rhodobacter%2C Corynebacterium and Rhizobium this protein is essential for growth gene gene555 http://www.ncbi.nlm.nih.gov/gene/?term=HI0543 HI0544 HI0544 rplI rplI 567767 568216 - 50S ribosomal protein L9 in Escherichia coli this protein is wrapped around the base of the L1 stalk gene gene556 http://www.ncbi.nlm.nih.gov/gene/?term=HI0544 HI0545 HI0545 rpsR rpsR 568233 568460 - 30S ribosomal protein S18 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA%3B helps stabilize the platform of the 30S subunit gene gene557 http://www.ncbi.nlm.nih.gov/gene/?term=HI0545 HI0546 HI0546 HI0546 568473 568799 - primosomal replication protein N binds single-stranded DNA at the primosome assembly site gene gene558 http://www.ncbi.nlm.nih.gov/gene/?term=HI0546 HI0547 HI0547 rpsF rpsF 568786 569163 - 30S ribosomal protein S6 binds cooperatively with S18 to the S15-16S complex%2C allowing platform assembly to continue with S11 and S21 gene gene559 http://www.ncbi.nlm.nih.gov/gene/?term=HI0547 HI0548 HI0548 infA infA 569362 569580 - translation initiation factor IF-1 stimulates the activities of the other two initiation factors%2C IF-2 and IF-3 gene gene560 http://www.ncbi.nlm.nih.gov/gene/?term=HI0548 HI0549 HI0549 ksgA ksgA 569786 570649 + dimethyladenosine transferase catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA%3B mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin gene gene561 http://www.ncbi.nlm.nih.gov/gene/?term=HI0549 HI0550 HI0550 HI0550 570690 571598 - lipooligosaccharide biosynthesis protein similar to GB:X56903 GB:L19441 gene gene562 http://www.ncbi.nlm.nih.gov/gene/?term=HI0550 HI0551 HI0551 apaH apaH 571717 572544 + diadenosine tetraphosphatase hydrolyzes P(1)%2CP(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP gene gene563 http://www.ncbi.nlm.nih.gov/gene/?term=HI0551 HI0552 HI0552 HI0552 572554 573177 + hypothetical protein gene gene564 http://www.ncbi.nlm.nih.gov/gene/?term=HI0552 HI0553 HI0553 gnd gnd 573303 574757 - 6-phosphogluconate dehydrogenase catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate gene gene565 http://www.ncbi.nlm.nih.gov/gene/?term=HI0553 HI0554 HI0554 HI0554 575203 575745 - hypothetical protein gene gene566 http://www.ncbi.nlm.nih.gov/gene/?term=HI0554 HI0555 HI0555 HI0555 575870 576109 - hypothetical protein similar to GB:M87483 SP:Q02009 PID:551879 gene gene567 http://www.ncbi.nlm.nih.gov/gene/?term=HI0555 HI0556 HI0556 devB devB 576109 576808 - gene gene568 http://www.ncbi.nlm.nih.gov/gene/?term=HI0556 HI0558 HI0558 zwf zwf 576891 578375 - glucose-6-phosphate 1-dehydrogenase catalyzes the formation of D-glucono-1%2C5-lactone 6-phosphate from D-glucose 6-phosphate gene gene569 http://www.ncbi.nlm.nih.gov/gene/?term=HI0558 HI0559 HI0559 cysQ cysQ 578451 579137 - 3'(2')%2C5'-bisphosphate nucleotidase CysQ similar to SP:P22255 GB:M55170 GB:M80795 PID:145275 PID:145690 gene gene570 http://www.ncbi.nlm.nih.gov/gene/?term=HI0559 HI0559.1 HI0559.1 HI0559.1 579332 579679 - hypothetical protein gene gene571 http://www.ncbi.nlm.nih.gov/gene/?term=HI0559.1 HI0561 HI0561 HI0561 579736 581637 - hypothetical protein similar to PID:1655665 gene gene572 http://www.ncbi.nlm.nih.gov/gene/?term=HI0561 HI0562 HI0562 HI0562 581951 582346 + hypothetical protein similar to SP:P45802 PID:606334 GB:U00096 PID:1789803 gene gene573 http://www.ncbi.nlm.nih.gov/gene/?term=HI0562 HI0563 HI0563 asnC asnC 582372 582824 - DNA-binding transcriptional regulator AsnC transcriptional repressor of asnA which codes for aspartate-ammonia ligase gene gene574 http://www.ncbi.nlm.nih.gov/gene/?term=HI0563 HI0564 HI0564 asnA asnA 582978 583970 + asparagine synthetase AsnA catalyzes the formation of asparagine from aspartate and ammonia gene gene575 http://www.ncbi.nlm.nih.gov/gene/?term=HI0564 HI0565 HI0565 gph gph 584035 584709 - phosphoglycolate phosphatase catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate gene gene576 http://www.ncbi.nlm.nih.gov/gene/?term=HI0565 HI0566 HI0566 dod dod 584755 585429 - ribulose-phosphate 3-epimerase catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate gene gene577 http://www.ncbi.nlm.nih.gov/gene/?term=HI0566 HI0567 HI0567 gyrB gyrB 585576 587996 - DNA gyrase subunit B negatively supercoils closed circular double-stranded DNA gene gene578 http://www.ncbi.nlm.nih.gov/gene/?term=HI0567 HI0568 HI0568 tex tex 588147 590435 - transcription accessory protein similar to SP:Q45388 PID:1477402 gene gene579 http://www.ncbi.nlm.nih.gov/gene/?term=HI0568 HI0569 HI0569 greB greB 590531 591007 + transcription elongation factor GreB necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites%3B arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through%2C resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus gene gene580 http://www.ncbi.nlm.nih.gov/gene/?term=HI0569 HI0570 HI0570 HI0570 591078 591695 - DNA-binding transcriptional repressor FabR negatively controls the expression of fabA and fabB%2C genes involved in the unsaturated fatty acid biosynthesis gene gene581 http://www.ncbi.nlm.nih.gov/gene/?term=HI0570 HI0571 HI0571 oxyR oxyR 591695 592600 - DNA-binding transcriptional regulator OxyR Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG%2C gor%2C ahpC%2C ahpF%2C oxyS%2C dps%2C fur and grxA gene gene582 http://www.ncbi.nlm.nih.gov/gene/?term=HI0571 HI0572 HI0572 HI0572 592723 593448 + peroxiredoxin hybrid Prx5 contains peroxiredoxin and glutaredoxin domains%3B forms homotetramers%3B similar to PID:1652858 gene gene583 http://www.ncbi.nlm.nih.gov/gene/?term=HI0572 HI0573 HI0573 slyX slyX 593536 593757 - hypothetical protein similar to GB:L13261 SP:P30857 PID:290468 PID:606282 GB:U00096 gene gene584 http://www.ncbi.nlm.nih.gov/gene/?term=HI0573 HI0574 HI0574 fkpA fkpA 593855 594580 + FKBP-type peptidyl-prolyl cis-trans isomerase similar to SP:P45523 SP:P45527 PID:606281 PID:862300 GB:U00096 gene gene585 http://www.ncbi.nlm.nih.gov/gene/?term=HI0574 HI0575 HI0575 HI0575 594669 595334 + hypothetical protein similar to SP:P45533 PID:606280 GB:U00096 PID:1789744 gene gene586 http://www.ncbi.nlm.nih.gov/gene/?term=HI0575 HI0576 HI0576 HI0576 595334 595714 + sulfur transfer complex subunit TusD in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs gene gene587 http://www.ncbi.nlm.nih.gov/gene/?term=HI0576 HI0576.1 HI0576.1 HI0576.1 595711 596070 + sulfur relay protein TusC in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs gene gene588 http://www.ncbi.nlm.nih.gov/gene/?term=HI0576.1 HI0577 HI0577 HI0577 596079 596366 + hypothetical protein gene gene589 http://www.ncbi.nlm.nih.gov/gene/?term=HI0577 HI0578 HI0578 tuf tuf 596497 597681 - elongation factor Tu EF-Tu%3B promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis%3B when the tRNA anticodon matches the mRNA codon%2C GTP hydrolysis results%3B the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts%3B many prokaryotes have two copies of the gene encoding EF-Tu gene gene590 http://www.ncbi.nlm.nih.gov/gene/?term=HI0578 HI0579 HI0579 fusA fusA 597746 599848 - elongation factor G EF-G%3B promotes GTP-dependent translocation of the ribosome during translation%3B many organisms have multiple copies of this gene gene gene591 http://www.ncbi.nlm.nih.gov/gene/?term=HI0579 HI0580 HI0580 rpS7 rpS7 599932 600402 - 30S ribosomal protein S7 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit gene gene592 http://www.ncbi.nlm.nih.gov/gene/?term=HI0580 HI0581 HI0581 rpsL rpsL 600559 600933 - 30S ribosomal protein S12 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone%3B located at the interface of the 30S and 50S subunits%2C it traverses the body of the 30S subunit contacting proteins on the other side%3B mutations in the S12 gene confer streptomycin resistance gene gene593 http://www.ncbi.nlm.nih.gov/gene/?term=HI0581 HI0582 HI0582 gidA gidA 601115 603004 - tRNA uridine 5-carboxymethylaminomethyl modification protein GidA GidA%3B glucose-inhibited cell division protein A%3B involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs gene gene594 http://www.ncbi.nlm.nih.gov/gene/?term=HI0582 HI0583 HI0583 cpdB cpdB 603690 605663 - 2'%2C3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic enzyme%3B functions during ribonucleic acid degradation%3B 2'%2C3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate gene gene595 http://www.ncbi.nlm.nih.gov/gene/?term=HI0583 HI0584 HI0584 HI0584 605757 607028 - hydrolase similar to GB:U00096 SP:P77357 PID:1742205 PID:1742209 PID:1787599 gene gene596 http://www.ncbi.nlm.nih.gov/gene/?term=HI0584 HI0585 HI0585 HI0585 607100 608394 - gene gene597 http://www.ncbi.nlm.nih.gov/gene/?term=HI0585 HI0587 HI0587 pepE pepE 608461 609117 - peptidase E alpha-aspartyl dipeptidase%3B catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue%3B belongs to peptidase S51 family gene gene598 http://www.ncbi.nlm.nih.gov/gene/?term=HI0587 HI0588 HI0588 HI0588 609241 610476 + allantoate amidohydrolase allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar%3B the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia%3B carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids%2C ammonia%2C and carbon dioxide gene gene599 http://www.ncbi.nlm.nih.gov/gene/?term=HI0588 HI0589 HI0589 HI0589 610691 611110 + sigma factor regulatory protein similar to SP:P46187 PID:987645 PID:1045631 PID:1050877 GB:U00096 gene gene600 http://www.ncbi.nlm.nih.gov/gene/?term=HI0589 HI0590 HI0590 potE potE 611212 612519 - putrescine transporter catalyzes the uptake of putrescine via a proton symport mechanism%2C as well as the efflux of putrescine by a putrescine/ornithine antiport system gene gene601 http://www.ncbi.nlm.nih.gov/gene/?term=HI0590 HI0591 HI0591 speF speF 612624 614786 - ornithine decarboxylase similar to GB:M64495 SP:P24169 PID:147331 GB:U00096 PID:1651300 gene gene602 http://www.ncbi.nlm.nih.gov/gene/?term=HI0591 HI0594 HI0594 HI0594 615772 617301 - hypothetical protein similar to GB:AE000783 gene gene603 http://www.ncbi.nlm.nih.gov/gene/?term=HI0594 HI0595 HI0595 arcC arcC 617406 618338 - carbamate kinase reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP gene gene604 http://www.ncbi.nlm.nih.gov/gene/?term=HI0595 HI0596 HI0596 arcB arcB 618348 619352 - ornithine carbamoyltransferase similar to GB:X05637 SP:P08308 PID:45288 gene gene605 http://www.ncbi.nlm.nih.gov/gene/?term=HI0596 HI0597 HI0597 HI0597 619754 620572 + hypothetical protein similar to SP:P27848 gene gene606 http://www.ncbi.nlm.nih.gov/gene/?term=HI0597 HI0597.1 HI0597.1 ccrB ccrB 620572 621054 + camphor resistance protein CrcB may be involved in chromosome condensation%3B overexpression in Escherichia coli protects against decondensation by camphor%3B overexpressing the protein results in an increase in supercoiling gene gene607 http://www.ncbi.nlm.nih.gov/gene/?term=HI0597.1 HI0599 HI0599 recX recX 620954 621412 - recombination regulator RecX binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities gene gene608 http://www.ncbi.nlm.nih.gov/gene/?term=HI0599 HI0600 HI0600 recA recA 621492 622556 - recombinase A catalyzes the hydrolysis of ATP in the presence of single-stranded DNA%2C the ATP-dependent uptake of single-stranded DNA by duplex DNA%2C and the ATP-dependent hybridization of homologous single-stranded DNAs gene gene609 http://www.ncbi.nlm.nih.gov/gene/?term=HI0600 HI0601 HI0601 tfoX tfoX 622876 623529 + DNA transformation protein similar to GB:U13205 PID:1573592 gene gene610 http://www.ncbi.nlm.nih.gov/gene/?term=HI0601 HI0601.1 HI0601.1 HI0601.1 629864 630282 + gene gene619 http://www.ncbi.nlm.nih.gov/gene/?term=HI0601.1 HI0601.2 HI0601.2 HIrrnA16S HIrrnA16S 623821 625369 + 16S ribosomal RNA rRNA gene611 http://www.ncbi.nlm.nih.gov/gene/?term=HI0601.2 HI0601.3 HI0601.3 HIrrnA23S HIrrnA23S 626083 628985 + 23S ribosomal RNA rRNA gene614 http://www.ncbi.nlm.nih.gov/gene/?term=HI0601.3 HI0601.4 HI0601.4 HIrrnA5S HIrrnA5S 629226 629354 + 5S ribosomal RNA rRNA gene615 http://www.ncbi.nlm.nih.gov/gene/?term=HI0601.4 HI0601.5 HI0601.5 tRNA-Trp-1 tRNA-Trp-1 629628 629703 + tRNA-Trp tRNA gene618 http://www.ncbi.nlm.nih.gov/gene/?term=HI0601.5 HI0601.6 HI0601.6 HI0601.6 625444 625520 + tRNA-Ile tRNA gene612 http://www.ncbi.nlm.nih.gov/gene/?term=HI0601.6 HI0601.7 HI0601.7 HI0601.7 625606 625681 + tRNA-Ala tRNA gene613 http://www.ncbi.nlm.nih.gov/gene/?term=HI0601.7 HI0601.8 HI0601.8 HI0601.8 629523 629599 + tRNA-Asp tRNA gene617 http://www.ncbi.nlm.nih.gov/gene/?term=HI0601.8 HI0601.9 HI0601.9 HI0601.9 629394 629512 + 5S ribosomal RNA rRNA gene616 http://www.ncbi.nlm.nih.gov/gene/?term=HI0601.9 HI0602 HI0602 hemY hemY 630346 631632 - protoheme synthesis protein HemY similar to GB:M87049 SP:P09128 GB:X12614 PID:148201 PID:41669 gene gene620 http://www.ncbi.nlm.nih.gov/gene/?term=HI0602 HI0603m HI0603m hemX hemX 631643 632856 - heme biosynthesis-like protein gene gene621 http://www.ncbi.nlm.nih.gov/gene/?term=HI0603m HI0604 HI0604 cyaA cyaA 633161 635692 + adenylate cyclase catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP gene gene622 http://www.ncbi.nlm.nih.gov/gene/?term=HI0604 HI0605 HI0605 gpsA gpsA 635766 636773 + NAD(P)H-dependent glycerol-3-phosphate dehydrogenase catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate gene gene623 http://www.ncbi.nlm.nih.gov/gene/?term=HI0605 HI0606 HI0606 cysE cysE 636785 637588 + serine acetyltransferase catalyzes the O-acetylation of serine gene gene624 http://www.ncbi.nlm.nih.gov/gene/?term=HI0606 HI0607 HI0607 aroE aroE 637598 638413 + shikimate 5-dehydrogenase catalyzes the conversion of shikimate to 3-dehydroshikimate gene gene625 http://www.ncbi.nlm.nih.gov/gene/?term=HI0607 HI0608 HI0608 HI0608 638552 639937 + di- and tricarboxylate transporter similar to GB:L77117 SP:Q58086 PID:1591386 gene gene626 http://www.ncbi.nlm.nih.gov/gene/?term=HI0608 HI0609 HI0609 folD folD 640075 640923 - bifunctional 5%2C10-methylene-tetrahydrofolate dehydrogenase/ 5%2C10-methylene-tetrahydrofolate cyclohydrolase catalyzes the formation of 5%2C10-methenyltetrahydrofolate from 5%2C10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5%2C10-methenyltetrahydrofolate gene gene627 http://www.ncbi.nlm.nih.gov/gene/?term=HI0609 HI0609.1 HI0609.1 HI0609.1 641105 641181 + tRNA-Pro tRNA gene628 http://www.ncbi.nlm.nih.gov/gene/?term=HI0609.1 HI0609.2 HI0609.2 HI0609.2 641229 641305 + tRNA-Arg tRNA gene629 http://www.ncbi.nlm.nih.gov/gene/?term=HI0609.2 HI0610 HI0610 fucP fucP 641451 642737 - L-fucose permease similar to SP:P11551 GB:X15025 PID:146041 PID:41504 PID:882696 gene gene630 http://www.ncbi.nlm.nih.gov/gene/?term=HI0610 HI0611 HI0611 fucA fucA 642776 643426 - L-fuculose phosphate aldolase catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate gene gene631 http://www.ncbi.nlm.nih.gov/gene/?term=HI0611 HI0612 HI0612 fucU fucU 643446 643880 - fucose operon protein similar to PID:882699 GB:U00096 PID:1789169 gene gene632 http://www.ncbi.nlm.nih.gov/gene/?term=HI0612 HI0613 HI0613 fucK fucK 643894 645306 - L-fuculokinase similar to SP:P11553 GB:X15025 PID:41506 PID:882698 GB:U00096 gene gene633 http://www.ncbi.nlm.nih.gov/gene/?term=HI0613 HI0614 HI0614 fucI fucI 645379 647148 - L-fucose isomerase catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose gene gene634 http://www.ncbi.nlm.nih.gov/gene/?term=HI0614 HI0615 HI0615 fucR fucR 647375 648124 - L-fucose operon activator similar to SP:P11554 GB:X15025 PID:41508 PID:882700 GB:U00096 gene gene635 http://www.ncbi.nlm.nih.gov/gene/?term=HI0615 HI0616 HI0616 hepA hepA 648322 651093 + ATP-dependent helicase HepA transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP%2C when it is trapped or immobilized on tightly supercoiled DNA gene gene636 http://www.ncbi.nlm.nih.gov/gene/?term=HI0616 HI0617 HI0617 HI0617 651096 651755 + hypothetical protein similar to SP:P39219 GB:U00096 PID:1786244 gene gene637 http://www.ncbi.nlm.nih.gov/gene/?term=HI0617 HI0618 HI0618 HI0618 651782 652360 + glp protein similar to GB:M54940 SP:P09391 GB:M96795 PID:146185 PID:146193 gene gene638 http://www.ncbi.nlm.nih.gov/gene/?term=HI0618 HI0619 HI0619 glpR glpR 652390 653157 + glycerol-3-phosphate regulon repressor similar to SP:P09392 GB:M96795 PID:146186 PID:606358 GB:U00096 gene gene639 http://www.ncbi.nlm.nih.gov/gene/?term=HI0619 HI0620 HI0620 hlpA hlpA 653459 654280 - D-methionine-binding lipoprotein MetQ similar to GB:M59804 SP:P31728 PID:1573614 gene gene640 http://www.ncbi.nlm.nih.gov/gene/?term=HI0620 HI0620.1 HI0620.1 HI0620.1 654319 654961 - gene gene641 http://www.ncbi.nlm.nih.gov/gene/?term=HI0620.1 HI0621 HI0621 metN metN 654999 656036 - DL-methionine transporter ATP-binding protein part of the metNIQ transport system for methionine gene gene642 http://www.ncbi.nlm.nih.gov/gene/?term=HI0621 HI0621.1 HI0621.1 HI0621.1 656212 656766 + D%2CD-heptose 1%2C7-bisphosphate phosphatase Converts the D-glycero-beta-D-manno-heptose 1%2C7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate gene gene643 http://www.ncbi.nlm.nih.gov/gene/?term=HI0621.1 HI0621.2 HI0621.2 HIrrnB16S HIrrnB16S 657103 658651 + 16S ribosomal RNA rRNA gene644 http://www.ncbi.nlm.nih.gov/gene/?term=HI0621.2 HI0621.3 HI0621.3 HIrrnB23S HIrrnB23S 659120 662022 + 23S ribosomal RNA rRNA gene646 http://www.ncbi.nlm.nih.gov/gene/?term=HI0621.3 HI0621.4 HI0621.4 HIrrnB5S HIrrnB5S 662263 662391 + 5S ribosomal RNA rRNA gene647 http://www.ncbi.nlm.nih.gov/gene/?term=HI0621.4 HI0621.5 HI0621.5 HI0621.5 658778 658853 + tRNA-Glu tRNA gene645 http://www.ncbi.nlm.nih.gov/gene/?term=HI0621.5 HI0622 HI0622 def def 662609 663118 + peptide deformylase cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins%3B binds iron(2+) gene gene648 http://www.ncbi.nlm.nih.gov/gene/?term=HI0622 HI0623 HI0623 fmt fmt 663211 664167 + methionyl-tRNA formyltransferase modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation%3B inactivation of this gene in Escherichia coli severely impairs growth gene gene649 http://www.ncbi.nlm.nih.gov/gene/?term=HI0623 HI0624 HI0624 sun sun 664167 665522 + 16S rRNA m5C967 methyltransferase similar to SP:P36929 SP:P36929 GB:X52114 PID:43136 PID:443992 gene gene650 http://www.ncbi.nlm.nih.gov/gene/?term=HI0624 HI0625 HI0625 trkA trkA 665535 666911 + potassium transporter peripheral membrane component involved in potassium uptake%3B found to be peripherally associated with the inner membrane in Escherichia coli%3B contains an NAD-binding domain gene gene651 http://www.ncbi.nlm.nih.gov/gene/?term=HI0625 HI0626 HI0626 mscL mscL 666984 667370 + large-conductance mechanosensitive channel forms homopentamer%3B channel that opens in response to pressure or hypoosmotic shock gene gene652 http://www.ncbi.nlm.nih.gov/gene/?term=HI0626 HI0627 HI0627 HI0627 667460 667717 + hypothetical protein similar to PID:887847 GB:U00096 SP:Q46825 PID:1789264 gene gene653 http://www.ncbi.nlm.nih.gov/gene/?term=HI0627 HI0628 HI0628 rpoE rpoE 667825 668394 + RNA polymerase sigma factor RpoE Member of the extracytoplasmic function sigma factors which are active under specific conditions%3B binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription%3B this sigma factor is involved in heat shock and oxidative stress response gene gene654 http://www.ncbi.nlm.nih.gov/gene/?term=HI0628 HI0629 HI0629 mclA mclA 668419 669006 + sigma-E factor negative regulatory protein similar to SP:P38106 GB:U10148 GB:U00096 PID:1788925 PID:987647 gene gene655 http://www.ncbi.nlm.nih.gov/gene/?term=HI0629 HI0630 HI0630 rseB rseB 669086 670033 + negative regulator of sigmaE periplasmic protein%3B interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP gene gene656 http://www.ncbi.nlm.nih.gov/gene/?term=HI0630 HI0631 HI0631 coaA coaA 670124 671059 - pantothenate kinase catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis gene gene657 http://www.ncbi.nlm.nih.gov/gene/?term=HI0631 HI0631.1 HI0631.1 tRNA-Tyr-1 tRNA-Tyr-1 671379 671463 + tRNA-Tyr tRNA gene659 http://www.ncbi.nlm.nih.gov/gene/?term=HI0631.1 HI0631.2 HI0631.2 tRNA-Gly-3 tRNA-Gly-3 671506 671580 + tRNA-Gly tRNA gene660 http://www.ncbi.nlm.nih.gov/gene/?term=HI0631.2 HI0631.3 HI0631.3 tRNA-Thr-2 tRNA-Thr-2 671584 671659 + tRNA-Thr tRNA gene661 http://www.ncbi.nlm.nih.gov/gene/?term=HI0631.3 HI0631.4 HI0631.4 HI0631.4 671274 671349 + tRNA-Thr tRNA gene658 http://www.ncbi.nlm.nih.gov/gene/?term=HI0631.4 HI0632 HI0632 tuf tuf 671764 672948 + elongation factor Tu EF-Tu%3B promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis%3B when the tRNA anticodon matches the mRNA codon%2C GTP hydrolysis results%3B the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts%3B many prokaryotes have two copies of the gene encoding EF-Tu gene gene662 http://www.ncbi.nlm.nih.gov/gene/?term=HI0632 HI0633 HI0633 HI0633 673116 673493 + hypothetical protein gene gene663 http://www.ncbi.nlm.nih.gov/gene/?term=HI0633 HI0634 HI0634 HI0634 673496 674479 + tRNA-dihydrouridine synthase A similar to SP:P32695 PID:396384 GB:U00096 PID:1790483 gene gene664 http://www.ncbi.nlm.nih.gov/gene/?term=HI0634 HI0635 HI0635 HI0635 674692 677850 - hemoglobin-binding protein similar to PID:1000292 PID:984513 gene gene665 http://www.ncbi.nlm.nih.gov/gene/?term=HI0635 HI0636 HI0636 HI0636 678239 678529 - hypothetical protein similar to GB:U00096 PID:1788685 gene gene666 http://www.ncbi.nlm.nih.gov/gene/?term=HI0636 HI0637 HI0637 trpS trpS 678551 679555 - tryptophan--tRNA ligase catalyzes a two-step reaction%2C first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA gene gene667 http://www.ncbi.nlm.nih.gov/gene/?term=HI0637 HI0638 HI0638 HI0638 679684 680301 + hypothetical protein HflD%3B UPF0274%3B in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein%3B in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis gene gene668 http://www.ncbi.nlm.nih.gov/gene/?term=HI0638 HI0639 HI0639 purB purB 680324 681694 + adenylosuccinate lyase Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide gene gene669 http://www.ncbi.nlm.nih.gov/gene/?term=HI0639 HI0640 HI0640 rplJ rplJ 681966 682457 + 50S ribosomal protein L10 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit gene gene670 http://www.ncbi.nlm.nih.gov/gene/?term=HI0640 HI0641 HI0641 rplL rplL 682512 682883 + 50S ribosomal protein L7/L12 rpL12 gene gene671 http://www.ncbi.nlm.nih.gov/gene/?term=HI0641 HI0642 HI0642 glmU glmU 683043 684413 + bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase forms a homotrimer%3B catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc%3B function in cell wall synthesis gene gene672 http://www.ncbi.nlm.nih.gov/gene/?term=HI0642 HI0642.1 HI0642.1 HI0642.1 685090 685184 - tRNA-Ser tRNA gene676 http://www.ncbi.nlm.nih.gov/gene/?term=HI0642.1 HI0642.2 HI0642.2 HI0642.2 684993 685069 - tRNA-Arg tRNA gene675 http://www.ncbi.nlm.nih.gov/gene/?term=HI0642.2 HI0642.3 HI0642.3 HI0642.3 684859 684935 - tRNA-Arg tRNA gene674 http://www.ncbi.nlm.nih.gov/gene/?term=HI0642.3 HI0642a HI0642a HI0642a 684452 684763 - hypothetical protein gene gene673 http://www.ncbi.nlm.nih.gov/gene/?term=HI0642a HI0643 HI0643 bisC bisC 685466 687943 - biotin sulfoxide reductase similar to SP:P46923 PID:1045667 GB:U00096 PID:1736518 PID:1736526 gene gene677 http://www.ncbi.nlm.nih.gov/gene/?term=HI0643 HI0644 HI0644 yecK yecK 687976 689076 - cytochrome C-like protein similar to SP:P52005 GB:U00096 PID:1736519 PID:1736527 PID:1788181 gene gene678 http://www.ncbi.nlm.nih.gov/gene/?term=HI0644 HI0645 HI0645 pldB pldB 689231 690172 - lysophospholipase L2 similar to PID:1449198 gene gene679 http://www.ncbi.nlm.nih.gov/gene/?term=HI0645 HI0646 HI0646 asd asd 690227 691342 - aspartate-semialdehyde dehydrogenase catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde gene gene680 http://www.ncbi.nlm.nih.gov/gene/?term=HI0646 HI0647 HI0647 HI0647 691501 692217 - transporter similar to GB:M57715 SP:P22037 PID:154179 gene gene681 http://www.ncbi.nlm.nih.gov/gene/?term=HI0647 HI0648 HI0648 mdaB mdaB 692495 693073 - modulator of drug activity B similar to SP:P40717 PID:609328 PID:882558 GB:U00096 PID:1789406 gene gene682 http://www.ncbi.nlm.nih.gov/gene/?term=HI0648 HI0649 HI0649 rep rep 693363 695375 - ATP-dependent DNA helicase similar to GB:M87049 SP:P09980 GB:X04794 PID:148182 GB:U00096 gene gene683 http://www.ncbi.nlm.nih.gov/gene/?term=HI0649 HI0650 HI0650 HI0650 695381 695593 - hypothetical protein gene gene684 http://www.ncbi.nlm.nih.gov/gene/?term=HI0650 HI0651 HI0651 coaD coaD 695590 696060 - phosphopantetheine adenylyltransferase Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA gene gene685 http://www.ncbi.nlm.nih.gov/gene/?term=HI0651 HI0652 HI0652 kdtA kdtA 696057 697340 - 3-deoxy-D-manno-octulosonic-acid transferase catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A gene gene686 http://www.ncbi.nlm.nih.gov/gene/?term=HI0652 HI0653 HI0653 HI0653 697403 698167 + lipopolysaccharide biosynthesis protein similar to PID:1389735 gene gene687 http://www.ncbi.nlm.nih.gov/gene/?term=HI0653 HI0654 HI0654 tagI tagI 698164 698721 - DNA-3-methyladenine glycosylase similar to SP:P05100 GB:J02606 GB:X03845 PID:147920 PID:43030 gene gene688 http://www.ncbi.nlm.nih.gov/gene/?term=HI0654 HI0655 HI0655 aroE aroE 698718 699536 - shikimate 5-dehydrogenase AroE%3B catalyzes the conversion of shikimate to 3-dehydroshikimate gene gene689 http://www.ncbi.nlm.nih.gov/gene/?term=HI0655 HI0656 HI0656 HI0656 699540 700091 - hypothetical protein similar to SP:P45748 PID:606216 GB:U00096 PID:2367210 gene gene690 http://www.ncbi.nlm.nih.gov/gene/?term=HI0656 HI0656.1 HI0656.1 HI0656.1 700107 700643 - hypothetical protein similar to SP:P45771 PID:606217 GB:U00096 PID:1789677 gene gene691 http://www.ncbi.nlm.nih.gov/gene/?term=HI0656.1 HI0658 HI0658 HI0658 700653 702569 - ABC transporter ATP-binding protein similar to SP:P45535 PID:606286 GB:U00096 PID:1789751 gene gene692 http://www.ncbi.nlm.nih.gov/gene/?term=HI0658 HI0659 HI0659 HI0659 702730 703026 - HTH-type transcriptional regulator gene gene693 http://www.ncbi.nlm.nih.gov/gene/?term=HI0659 HI0660 HI0660 HI0660 703019 703378 - hypothetical protein gene gene694 http://www.ncbi.nlm.nih.gov/gene/?term=HI0660 HI0661 HI0661 oapA oapA 703648 706680 - hemoglobin-binding protein similar to PID:1000292 PID:984513 gene gene695 http://www.ncbi.nlm.nih.gov/gene/?term=HI0661 HI0663m HI0663m cydD cydD 707165 708910 + ABC transporter ATP-binding protein gene gene696 http://www.ncbi.nlm.nih.gov/gene/?term=HI0663m HI0664 HI0664 HI0664 708903 710561 + ABC transporter ATP-binding protein similar to GB:AL009126 gene gene697 http://www.ncbi.nlm.nih.gov/gene/?term=HI0664 HI0665 HI0665 HI0665 710645 711676 - hypothetical protein gene gene698 http://www.ncbi.nlm.nih.gov/gene/?term=HI0665 HI0666 HI0666 HI0666 711673 711993 - hypothetical protein gene gene699 http://www.ncbi.nlm.nih.gov/gene/?term=HI0666 HI0666.1 HI0666.1 HI0666.1 711981 712289 - hypothetical protein gene gene700 http://www.ncbi.nlm.nih.gov/gene/?term=HI0666.1 HI0667 HI0667 glpX glpX 712489 713490 - fructose 1%2C6-bisphosphatase II type II fructose 1%2C6-bisphosphatae%3B in Escherichia coli this protein forms a dimer and binds manganese gene gene701 http://www.ncbi.nlm.nih.gov/gene/?term=HI0667 HI0668 HI0668 HI0668 713652 713870 + hypothetical protein similar to GB:L19201 SP:P32164 PID:305031 GB:U00096 PID:1790363 gene gene702 http://www.ncbi.nlm.nih.gov/gene/?term=HI0668 HI0669 HI0669 mioC mioC 713967 714407 + flavodoxin An electron-transfer protein%3B flavodoxin binds one FMN molecule%2C which serves as a redox-active prosthetic group gene gene703 http://www.ncbi.nlm.nih.gov/gene/?term=HI0669 HI0670 HI0670 HI0670 714404 714838 + D-tyrosyl-tRNA(Tyr) deacylase hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr)%3B possible defense mechanism against a harmful effect of D-tyrosine gene gene704 http://www.ncbi.nlm.nih.gov/gene/?term=HI0670 HI0671 HI0671 ispF ispF 715140 715616 - 2-C-methyl-D-erythritol 2%2C4-cyclodiphosphate synthase catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2%2C4-cyclodiphosphate gene gene705 http://www.ncbi.nlm.nih.gov/gene/?term=HI0671 HI0672 HI0672 ispD ispD 715613 716290 - 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 4-diphosphocytidyl-2C-methyl-D-erythritol synthase%3B MEP cytidylyltransferase%3B MCT%3B catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate%3B involved in isoprenoid and isopentenyl-PP biosynthesis%3B forms homodimers gene gene706 http://www.ncbi.nlm.nih.gov/gene/?term=HI0672 HI0673 HI0673 ftsB ftsB 716290 716568 - cell division protein FtsB forms a complex with FtsL and FtsQ%3B colocalizes to the septal region of the dividing cell%3B membrane protein gene gene707 http://www.ncbi.nlm.nih.gov/gene/?term=HI0673 HI0674 HI0674 gptA gptA 716691 717158 - xanthine-guanine phosphoribosyltransferase catalyzes the conversion of guanine%2C xanthine and%2C to a lesser extent%2C hypoxanthine to GMP%2C XMP and IMP%2C respectively gene gene708 http://www.ncbi.nlm.nih.gov/gene/?term=HI0674 HI0675 HI0675 pepD pepD 717269 718723 + aminoacyl-histidine dipeptidase similar to GB:M34034 SP:P15288 GB:X14790 PID:1208983 PID:147140 gene gene709 http://www.ncbi.nlm.nih.gov/gene/?term=HI0675 HI0676 HI0676 xerC xerC 718776 719663 - site-specific tyrosine recombinase XerC site-specific tyrosine recombinase which cuts and rejoins DNA molecules%3B binds cooperatively to specific DNA consensus sites%3B forms a heterotetrameric complex with XerC%3B XerCD exhibit similar sequences%3B essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation%3B cell division protein FtsK may regulate the XerCD complex%3B enzyme from Streptococcus group has unusual active site motifs gene gene710 http://www.ncbi.nlm.nih.gov/gene/?term=HI0676 HI0677 HI0677 HI0677 719657 720097 - hypothetical protein gene gene711 http://www.ncbi.nlm.nih.gov/gene/?term=HI0677 HI0678 HI0678 tpiA tpiA 720263 721054 + triosephosphate isomerase Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate gene gene712 http://www.ncbi.nlm.nih.gov/gene/?term=HI0678 HI0679 HI0679 glpE glpE 721137 721454 - thiosulfate sulfurtransferase GlpE similar to GB:X07520 SP:P09390 GB:M96795 PID:146184 PID:146192 gene gene713 http://www.ncbi.nlm.nih.gov/gene/?term=HI0679 HI0680 HI0680 HI0680 721436 722332 - RarD protein similar to SP:P27844 gene gene714 http://www.ncbi.nlm.nih.gov/gene/?term=HI0680 HI0681 HI0681 ilvY ilvY 722364 723242 - DNA-binding transcriptional regulator IlvY participates in controlling several genes involved in isoleucine and valine biosynthesis%3B activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate gene gene715 http://www.ncbi.nlm.nih.gov/gene/?term=HI0681 HI0682 HI0682 ilvC ilvC 723919 725397 + ketol-acid reductoisomerase catalyzes the formation of (R)-2%2C3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis gene gene716 http://www.ncbi.nlm.nih.gov/gene/?term=HI0682 HI0683 HI0683 glpC glpC 725508 726788 - sn-glycerol-3-phosphate dehydrogenase subunit C anaerobic%3B with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate gene gene717 http://www.ncbi.nlm.nih.gov/gene/?term=HI0683 HI0684 HI0684 glpB glpB 726800 728098 - anaerobic glycerol-3-phosphate dehydrogenase subunit B sn-glycerol-3-phosphate dehydrogenase (anaerobic)%3B catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate%3B part of GlpABC complex%3B presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters gene gene718 http://www.ncbi.nlm.nih.gov/gene/?term=HI0684 HI0685 HI0685 glpA glpA 728088 729779 - sn-glycerol-3-phosphate dehydrogenase subunit A anaerobic%2C catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor gene gene719 http://www.ncbi.nlm.nih.gov/gene/?term=HI0685 HI0686 HI0686 glpT glpT 730072 731514 + glycerol-3-phosphatase transporter similar to SP:P08194 GB:Y00536 PID:41587 GB:U00096 PID:1788573 gene gene720 http://www.ncbi.nlm.nih.gov/gene/?term=HI0686 HI0687 HI0687 HI0687 731614 732528 + hypothetical protein similar to GB:D26185 SP:P37511 PID:467365 GB:AL009126 gene gene721 http://www.ncbi.nlm.nih.gov/gene/?term=HI0687 HI0688 HI0688 HI0688 732623 732934 + hypothetical protein gene gene722 http://www.ncbi.nlm.nih.gov/gene/?term=HI0688 HI0689 HI0689 glpQ glpQ 732946 734040 + glycerophosphodiester phosphodiesterase hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols%3B periplasmic gene gene723 http://www.ncbi.nlm.nih.gov/gene/?term=HI0689 HI0690 HI0690 glpF glpF 734270 735064 + glycerol uptake facilitator protein similar to GB:L19201 SP:P11244 GB:M55990 GB:U13915 GB:X15054 gene gene724 http://www.ncbi.nlm.nih.gov/gene/?term=HI0690 HI0691 HI0691 glpK glpK 735085 736596 + glycerol kinase Converts glycerol and ADP to glycerol-3-phosphate and ADP gene gene725 http://www.ncbi.nlm.nih.gov/gene/?term=HI0691 HI0692 HI0692 gptB gptB 736671 737138 - xanthine-guanine phosphoribosyltransferase catalyzes the conversion of guanine%2C xanthine and%2C to a lesser extent%2C hypoxanthine to GMP%2C XMP and IMP%2C respectively gene gene726 http://www.ncbi.nlm.nih.gov/gene/?term=HI0692 HI0693 HI0693 hel hel 737422 738246 + lipoprotein E similar to GB:M68502 SP:P26093 PID:1573696 gene gene727 http://www.ncbi.nlm.nih.gov/gene/?term=HI0693 HI0694 HI0694 HI0694 738386 739108 + 23S rRNA pseudouridine synthase E similar to GB:U00096 SP:P75966 PID:1787380 gene gene728 http://www.ncbi.nlm.nih.gov/gene/?term=HI0694 HI0695 HI0695 HI0695 739234 740205 - exopolyphosphatase similar to GB:L06129 SP:P29014 PID:147343 GB:U00096 PID:1788848 gene gene729 http://www.ncbi.nlm.nih.gov/gene/?term=HI0695 HI0696 HI0696 HI0696 740213 744109 - hypothetical protein similar to GB:U14003 SP:P39321 PID:537063 GB:U00096 gene gene730 http://www.ncbi.nlm.nih.gov/gene/?term=HI0696 HI0698 HI0698 HI0698 744119 745855 - hypothetical protein similar to GB:U14003 SP:P39320 PID:537061 GB:U00096 PID:1790666 gene gene731 http://www.ncbi.nlm.nih.gov/gene/?term=HI0698 HI0699 HI0699 slyD slyD 746006 746578 - peptidyl-prolyl cis-trans isomerase similar to GB:L13261 SP:P30856 GB:Z21496 PID:394720 PID:475995 gene gene732 http://www.ncbi.nlm.nih.gov/gene/?term=HI0699 HI0700 HI0700 HI0700 746658 747119 - hypothetical protein similar to SP:P37163 GB:U14003 PID:537096 GB:U00096 PID:1790704 gene gene733 http://www.ncbi.nlm.nih.gov/gene/?term=HI0700 HI0701 HI0701 truD truD 747228 748247 + tRNA pseudouridine synthase D catalyzes the modification of U13 in tRNA(Glu) gene gene734 http://www.ncbi.nlm.nih.gov/gene/?term=HI0701 HI0702 HI0702 surE surE 748257 749006 + 5'-nucleotidase SurE catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate gene gene735 http://www.ncbi.nlm.nih.gov/gene/?term=HI0702 HI0703 HI0703 lppB lppB 749015 749593 + lipoprotein B similar to GB:L10653 SP:P36684 PID:148929 gene gene736 http://www.ncbi.nlm.nih.gov/gene/?term=HI0703 HI0704 HI0704 HI0704 749602 749787 + hypothetical protein gene gene737 http://www.ncbi.nlm.nih.gov/gene/?term=HI0704 HI0706 HI0706 HI0706 749811 751028 + lipoprotein similar to GB:L07869 SP:P33648 PID:404099 PID:433185 PID:882635 gene gene738 http://www.ncbi.nlm.nih.gov/gene/?term=HI0706 HI0707 HI0707 mutS mutS 751161 753746 + DNA mismatch repair protein MutS This protein performs the mismatch recognition step during the DNA repair process gene gene739 http://www.ncbi.nlm.nih.gov/gene/?term=HI0707 HI0707.1 HI0707.1 tRNA-SeC(p)-1 tRNA-SeC(p)-1 753791 753881 - tRNA-Sec tRNA gene740 http://www.ncbi.nlm.nih.gov/gene/?term=HI0707.1 HI0708 HI0708 selA selA 753952 755337 + selenocysteine synthase catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis gene gene741 http://www.ncbi.nlm.nih.gov/gene/?term=HI0708 HI0709 HI0709 selB selB 755334 757193 + selenocysteine-specific elongation factor similar to SP:P14081 GB:X16644 PID:42937 PID:466728 GB:U00096 gene gene742 http://www.ncbi.nlm.nih.gov/gene/?term=HI0709 HI0710 HI0710 HI0710 757421 757717 + hypothetical protein gene gene743 http://www.ncbi.nlm.nih.gov/gene/?term=HI0710 HI0711 HI0711 HI0711 757717 758025 + hypothetical protein similar to PID:984581 GB:U00096 SP:Q47149 PID:1786419 gene gene744 http://www.ncbi.nlm.nih.gov/gene/?term=HI0711 HI0712 HI0712 HI0712 758082 761336 - hemoglobin-binding protein similar to PID:1000292 PID:984513 gene gene745 http://www.ncbi.nlm.nih.gov/gene/?term=HI0712 HI0713 HI0713 tig tig 761637 762935 + trigger factor Tig%3B RopA%3B peptidyl-prolyl cis/trans isomerase%3B promotes folding of newly synthesized proteins%3B binds ribosomal 50S subunit%3B forms a homodimer gene gene746 http://www.ncbi.nlm.nih.gov/gene/?term=HI0713 HI0714 HI0714 clpP clpP 763058 763639 + ATP-dependent Clp protease proteolytic subunit hydrolyzes proteins to small peptides%3B with the ATPase subunits ClpA or ClpX%2C ClpP degrades specific substrates gene gene747 http://www.ncbi.nlm.nih.gov/gene/?term=HI0714 HI0715 HI0715 clpX clpX 763649 764884 + ATP-dependent protease ATP-binding subunit ClpX binds and unfolds substrates as part of the ClpXP protease gene gene748 http://www.ncbi.nlm.nih.gov/gene/?term=HI0715 HI0716 HI0716 secE secE 765122 765442 + preprotein translocase subunit SecE forms a complex with SecY and SecG%3B SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane%2C a process driven by ATP and a proton-motive force gene gene749 http://www.ncbi.nlm.nih.gov/gene/?term=HI0716 HI0717 HI0717 nusG nusG 765444 766001 + transcription antitermination protein NusG Modulates Rho-dependent transcription termination gene gene750 http://www.ncbi.nlm.nih.gov/gene/?term=HI0717 HI0718 HI0718 vacJ vacJ 766152 766904 + lipoprotein similar to SP:P43262 PID:904221 gene gene751 http://www.ncbi.nlm.nih.gov/gene/?term=HI0718 HI0719 HI0719 HI0719 766958 767350 + hypothetical protein unknown function%3B forms homotrimers%3B binds small molecules of alpha-keto acids or alpha%2Cbeta-unsaturated acids%3B similar to GB:U14003 SP:P39330 PID:537085 GB:U00096 PID:1790691 gene gene752 http://www.ncbi.nlm.nih.gov/gene/?term=HI0719 HI0720 HI0720 htpX htpX 767518 768369 + heat shock protein HtpX metalloprotease gene gene753 http://www.ncbi.nlm.nih.gov/gene/?term=HI0720 HI0721 HI0721 HI0721 768411 768650 - sulfur transfer protein SirA TusA%3B transfers sulfur to TusBCD complex%3B involved in thiouridation of U34 position of some tRNAs gene gene754 http://www.ncbi.nlm.nih.gov/gene/?term=HI0721 HI0722 HI0722 HI0722 768754 769386 + hypothetical protein similar to GB:U00096 PID:1790283 gene gene755 http://www.ncbi.nlm.nih.gov/gene/?term=HI0722 HI0723 HI0723 trkH trkH 769389 770852 + Trk system potassium uptake protein TrkH similar to GB:M87049 SP:P21166 PID:148249 PID:42359 PID:2367317 gene gene756 http://www.ncbi.nlm.nih.gov/gene/?term=HI0723 HI0723.1 HI0723.1 HIrrnC16S HIrrnC16S 771206 772754 + 16S ribosomal RNA rRNA gene757 http://www.ncbi.nlm.nih.gov/gene/?term=HI0723.1 HI0723.2 HI0723.2 tRNA-Ile-2 tRNA-Ile-2 772829 772905 + tRNA-Ile tRNA gene758 http://www.ncbi.nlm.nih.gov/gene/?term=HI0723.2 HI0723.3 HI0723.3 HIrrnC23S HIrrnC23S 773468 776370 + 23S ribosomal RNA rRNA gene760 http://www.ncbi.nlm.nih.gov/gene/?term=HI0723.3 HI0723.4 HI0723.4 HIrrnC5S HIrrnC5S 776611 776739 + 5S ribosomal RNA rRNA gene761 http://www.ncbi.nlm.nih.gov/gene/?term=HI0723.4 HI0723.5 HI0723.5 HI0723.5 772991 773066 + tRNA-Ala tRNA gene759 http://www.ncbi.nlm.nih.gov/gene/?term=HI0723.5 HI0724 HI0724 HI0724 776909 777469 + hypothetical protein similar to PID:1685095 gene gene762 http://www.ncbi.nlm.nih.gov/gene/?term=HI0724 HI0725 HI0725 HI0725 777473 777913 + hypothetical protein similar to PID:1685094 gene gene763 http://www.ncbi.nlm.nih.gov/gene/?term=HI0725 HI0726 HI0726 narP narP 777975 778601 - nitrate/nitrite response regulator protein similar to GB:U00008 SP:P31802 GB:L11273 PID:304917 PID:405947 gene gene764 http://www.ncbi.nlm.nih.gov/gene/?term=HI0726 HI0727 HI0727 lysA lysA 778807 780054 - diaminopimelate decarboxylase similar to SP:P19572 gene gene765 http://www.ncbi.nlm.nih.gov/gene/?term=HI0727 HI0727.1 HI0727.1 cyaY cyaY 780315 780620 + frataxin-like protein defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease%3B based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly gene gene766 http://www.ncbi.nlm.nih.gov/gene/?term=HI0727.1 HI0728 HI0728 recQ recQ 780622 782481 + ATP-dependent DNA helicase similar to GB:M87049 SP:P15043 GB:M30198 PID:147559 PID:148221 gene gene767 http://www.ncbi.nlm.nih.gov/gene/?term=HI0728 HI0729 HI0729 proS proS 782566 784284 + proline--tRNA ligase catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) gene gene768 http://www.ncbi.nlm.nih.gov/gene/?term=HI0729 HI0730 HI0730 HI0730 784372 786720 - organic solvent tolerance protein determines N-hexane tolerance and is involved in outer membrane permeability gene gene769 http://www.ncbi.nlm.nih.gov/gene/?term=HI0730 HI0732 HI0732 HI0732 786840 788245 - gene gene770 http://www.ncbi.nlm.nih.gov/gene/?term=HI0732 HI0734 HI0734 plsC plsC 788247 788969 - 1-acylglycerol-3-phosphate O-acyltransferase similar to GB:M63491 SP:P26647 PID:147298 PID:882548 GB:U00096 gene gene771 http://www.ncbi.nlm.nih.gov/gene/?term=HI0734 HI0735 HI0735 HI0735 789055 789768 + UDP-2%2C3-diacylglucosamine hydrolase catalyzes the formation of 2%2C3%3Ddiacylglucosamine 1-phosphate from UDP-2%2C3%3Ddiacylglucosamine gene gene772 http://www.ncbi.nlm.nih.gov/gene/?term=HI0735 HI0736 HI0736 HI0736 789998 791524 - sodium-dependent transporter similar to GB:AE000782 gene gene773 http://www.ncbi.nlm.nih.gov/gene/?term=HI0736 HI0737 HI0737 HI0737 791772 792569 + acetohydroxy acid synthase II similar to GB:M10313 SP:P00892 GB:M32253 GB:V00290 GB:X04890 gene gene774 http://www.ncbi.nlm.nih.gov/gene/?term=HI0737 HI0738 HI0738 ilvD ilvD 792641 794479 + dihydroxy-acid dehydratase catalyzes the dehydration of 2%2C3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis gene gene775 http://www.ncbi.nlm.nih.gov/gene/?term=HI0738 HI0738.1 HI0738.1 ilvA ilvA 794559 796100 + threonine dehydratase threonine deaminase%3B threonine dehydratase%3B in Escherichia coli%2C IlvA is part of the isoleucine biosynthetic pathway gene gene776 http://www.ncbi.nlm.nih.gov/gene/?term=HI0738.1 HI0739 HI0739 dnaE dnaE 796139 799618 - DNA polymerase III subunit alpha catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time%3B main replicative polymerase gene gene777 http://www.ncbi.nlm.nih.gov/gene/?term=HI0739 HI0740 HI0740 yhxB yhxB 799857 801509 + phosphomannomutase similar to GB:M34393 SP:P18159 PID:142994 PID:2226139 GB:AL009126 gene gene778 http://www.ncbi.nlm.nih.gov/gene/?term=HI0740 HI0742 HI0742 HI0742 801658 801987 + hypothetical protein gene gene779 http://www.ncbi.nlm.nih.gov/gene/?term=HI0742 HI0743 HI0743 secB secB 802054 802563 - preprotein translocase subunit SecB molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm%3B in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA gene gene780 http://www.ncbi.nlm.nih.gov/gene/?term=HI0743 HI0744 HI0744 HI0744 802577 803023 - hypothetical protein similar to SP:P37688 PID:466749 GB:U00096 PID:1790040 gene gene781 http://www.ncbi.nlm.nih.gov/gene/?term=HI0744 HI0745 HI0745 ansB ansB 803249 804298 + L-asparaginase II catalyzes the formation of aspartate from asparagine%2C periplasmic%3B regulated by cyclic AMP receptor protein (CRP) and also induced by anaerobiosis gene gene782 http://www.ncbi.nlm.nih.gov/gene/?term=HI0745 HI0746 HI0746 dcuB dcuB 804454 805776 + anaerobic C4-dicarboxylate transporter functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate%3B similar to dcuB gene gene783 http://www.ncbi.nlm.nih.gov/gene/?term=HI0746 HI0747 HI0747 ndh ndh 805980 807314 + NADH dehydrogenase similar to SP:P00393 PID:581140 GB:U00096 PID:1651546 PID:1787352 gene gene784 http://www.ncbi.nlm.nih.gov/gene/?term=HI0747 HI0748 HI0748 HI0748 807394 809826 - glycerol-3-phosphate acyltransferase PlsB%3B catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA gene gene785 http://www.ncbi.nlm.nih.gov/gene/?term=HI0748 HI0749 HI0749 lexA lexA 810081 810704 + LexA repressor Represses a number of genes involved in the response to DNA damage gene gene786 http://www.ncbi.nlm.nih.gov/gene/?term=HI0749 HI0750 HI0750 dapF dapF 810848 811672 + diaminopimelate epimerase involved in lysine biosynthesis%3B DAP epimerase%3B produces DL-diaminopimelate from LL-diaminopimelate gene gene787 http://www.ncbi.nlm.nih.gov/gene/?term=HI0750 HI0751 HI0751 tpx tpx 811891 812388 - 2-Cys peroxiredoxin antioxidant activity%3B thioredoxin-dependent thiol peroxidase%3B forms homodimers in solution%3B shows substrate specificity to alkyl hydroperoxides%3B periplasmic protein gene gene788 http://www.ncbi.nlm.nih.gov/gene/?term=HI0751 HI0752 HI0752 purL purL 812967 816929 + phosphoribosylformylglycinamidine synthase catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis gene gene789 http://www.ncbi.nlm.nih.gov/gene/?term=HI0752 HI0753 HI0753 anmK anmK 817101 818249 + anhydro-N-acetylmuramic acid kinase catalyzes hydrolysis of 1%2C6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate%3B involved in murein recycling gene gene790 http://www.ncbi.nlm.nih.gov/gene/?term=HI0753 HI0754 HI0754 murQ murQ 818259 819170 + N-acetylmuramic acid-6-phosphate etherase catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate%3B involved in MurNAc dissimilation pathway gene gene791 http://www.ncbi.nlm.nih.gov/gene/?term=HI0754 HI0755 HI0755 dat1 dat1 819200 820042 - hypothetical protein similar to SP:P37691 PID:912478 GB:U00096 PID:1790043 gene gene792 http://www.ncbi.nlm.nih.gov/gene/?term=HI0755 HI0756 HI0756 HI0756 820042 821274 - hypothetical protein similar to SP:P37690 PID:466751 GB:U00096 PID:1790042 gene gene793 http://www.ncbi.nlm.nih.gov/gene/?term=HI0756 HI0757 HI0757 gpmA gpmA 821450 822133 + 2%2C3-bisphosphoglycerate-dependent phosphoglycerate mutase 2%2C3-bisphosphoglycerate-dependent%3B catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate gene gene794 http://www.ncbi.nlm.nih.gov/gene/?term=HI0757 HI0758 HI0758 rpmE rpmE 822211 822423 - 50S ribosomal protein L31 RpmE%3B there appears to be two types of ribosomal proteins L31 in bacterial genomes%3B some contain a CxxC motif while others do not%3B Bacillus subtilis has both types%3B the proteins in this cluster have the CXXC motif%3B RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth%3B expression of ytiA is controlled by a zinc-specific transcriptional repressor%3B RpmE contains one zinc ion and a CxxC motif is responsible for this binding%3B forms an RNP particle along with proteins L5%2C L18%2C and L25 and 5S rRNA%3B found crosslinked to L2 and L25 and EF-G%3B may be near the peptidyltransferase site of the 50S ribosome gene gene795 http://www.ncbi.nlm.nih.gov/gene/?term=HI0758 HI0759 HI0759 mutY mutY 822600 823736 + A/G-specific adenine glycosylase similar to GB:M59471 SP:P17802 GB:X52391 PID:146864 PID:42073 gene gene796 http://www.ncbi.nlm.nih.gov/gene/?term=HI0759 HI0760 HI0760 HI0760 823714 823986 + hypothetical protein similar to PID:882491 SP:P52065 GB:U00096 PID:1789332 gene gene797 http://www.ncbi.nlm.nih.gov/gene/?term=HI0760 HI0761 HI0761 mltC mltC 824001 825074 + murein transglycosylase C Murein hydrolase C%3B membrane-bound%3B lytic%3B catalyzes the cleavage of the beta-1%2C4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues gene gene798 http://www.ncbi.nlm.nih.gov/gene/?term=HI0761 HI0761.1 HI0761.1 HI0761.1 825313 825388 + tRNA-Phe tRNA gene799 http://www.ncbi.nlm.nih.gov/gene/?term=HI0761.1 HI0761.2 HI0761.2 HI0761.2 825391 825466 + tRNA-Asn tRNA gene800 http://www.ncbi.nlm.nih.gov/gene/?term=HI0761.2 HI0762 HI0762 HI0762 825685 826365 - hypothetical protein gene gene801 http://www.ncbi.nlm.nih.gov/gene/?term=HI0762 HI0763 HI0763 nadR nadR 826362 827627 - nicotinamide-nucleotide adenylyltransferase catalyzes the formation of NAD(+) from nicotinamide ribonucleotide gene gene802 http://www.ncbi.nlm.nih.gov/gene/?term=HI0763 HI0764 HI0764 ribB ribB 827846 828493 + 3%2C4-dihydroxy-2-butanone-4-phosphate synthase DHBP synthase%3B functions during riboflavin biosynthesis gene gene803 http://www.ncbi.nlm.nih.gov/gene/?term=HI0764 HI0765 HI0765 HI0765 828520 829356 + lipooligosaccharide biosynthesis protein similar to GB:M37913 GB:L19441 PID:1573535 gene gene804 http://www.ncbi.nlm.nih.gov/gene/?term=HI0765 HI0766 HI0766 yibK yibK 829405 829887 - RNA methyltransferase YibK%3B binds cofactor S-adenosylhomocysteine%3B similar to SP:P33899 PID:466744 GB:U00096 PID:1790034 gene gene805 http://www.ncbi.nlm.nih.gov/gene/?term=HI0766 HI0767 HI0767 HI0767 829898 830479 - hypothetical protein similar to SP:P10120 GB:U00039 GB:X04398 PID:41497 PID:466601 gene gene806 http://www.ncbi.nlm.nih.gov/gene/?term=HI0767 HI0768 HI0768 ftsY ftsY 830534 831778 + cell division protein FtsY similar to SP:P10121 GB:U00039 GB:X04398 PID:41498 PID:466600 gene gene807 http://www.ncbi.nlm.nih.gov/gene/?term=HI0768 HI0769 HI0769 ftsE ftsE 831797 832453 + cell division ATP-binding protein similar to SP:P10115 GB:U00039 GB:X04398 PID:41499 PID:466599 gene gene808 http://www.ncbi.nlm.nih.gov/gene/?term=HI0769 HI0770 HI0770 ftsX ftsX 832463 833395 + cell division protein FtsX ABC transporter%2C membrane protein gene gene809 http://www.ncbi.nlm.nih.gov/gene/?term=HI0770 HI0771 HI0771 atoB atoB 833490 834671 - acetyl-CoA acetyltransferase similar to GB:U00096 SP:P76461 PID:1736879 PID:1788554 PID:1799573 gene gene810 http://www.ncbi.nlm.nih.gov/gene/?term=HI0771 HI0772 HI0772 atoE atoE 834686 836029 - short chain fatty acids transporter similar to GB:U00096 SP:P76460 PID:1788553 gene gene811 http://www.ncbi.nlm.nih.gov/gene/?term=HI0772 HI0773 HI0773 atoA atoA 836026 836697 - acetate CoA-transferase subunit beta similar to GB:U00096 SP:P76459 PID:1736877 PID:1788552 gene gene812 http://www.ncbi.nlm.nih.gov/gene/?term=HI0773 HI0774 HI0774 HI0774 836708 837361 - acetyl-CoA:acetoacetyl-CoA transferase subunit alpha similar to GB:U00096 SP:P76458 PID:1736876 PID:1788551 gene gene813 http://www.ncbi.nlm.nih.gov/gene/?term=HI0774 HI0775 HI0775 HI0775 837609 838514 + transcriptional regulator similar to GB:X73124 SP:P39592 PID:413948 GB:AL009126 gene gene814 http://www.ncbi.nlm.nih.gov/gene/?term=HI0775 HI0776 HI0776 rpsJ rpsJ 838750 839061 + 30S ribosomal protein S10 NusE%3B involved in assembly of the 30S subunit%3B in the ribosome%2C this protein is involved in the binding of tRNA%3B in Escherichia coli this protein was also found to be involved in transcription antitermination%3B NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination%3B binding of NusB/S10 to boxA nucleates assembly of the antitermination complex gene gene815 http://www.ncbi.nlm.nih.gov/gene/?term=HI0776 HI0777 HI0777 rplC rplC 839078 839704 + 50S ribosomal protein L3 binds directly near the 3' end of the 23S rRNA%2C where it nucleates assembly of the 50S subunit%3B essential for peptidyltransferase activity%3B mutations in this gene confer resistance to tiamulin gene gene816 http://www.ncbi.nlm.nih.gov/gene/?term=HI0777 HI0778 HI0778 rplD rplD 839720 840322 + 50S ribosomal protein L4 L4 is important during the early stages of 50S assembly%3B it initially binds near the 5' end of the 23S rRNA gene gene817 http://www.ncbi.nlm.nih.gov/gene/?term=HI0778 HI0779 HI0779 rplW rplW 840319 840618 + 50S ribosomal protein L23 binds third domain of 23S rRNA and protein L29%3B part of exit tunnel gene gene818 http://www.ncbi.nlm.nih.gov/gene/?term=HI0779 HI0780 HI0780 rplB rplB 840636 841457 + 50S ribosomal protein L2 one of the primary rRNA-binding proteins%3B required for association of the 30S and 50S subunits to form the 70S ribosome%2C for tRNA binding and peptide bond formation gene gene819 http://www.ncbi.nlm.nih.gov/gene/?term=HI0780 HI0781 HI0781 rpsS rpsS 841483 841758 + 30S ribosomal protein S19 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA gene gene820 http://www.ncbi.nlm.nih.gov/gene/?term=HI0781 HI0782 HI0782 rplV rplV 841770 842102 + 50S ribosomal protein L22 binds specifically to 23S rRNA during the early stages of 50S assembly%3B makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome%3B mutations in this gene result in erythromycin resistance%3B located near peptidyl-transferase center gene gene821 http://www.ncbi.nlm.nih.gov/gene/?term=HI0782 HI0783 HI0783 rpsC rpsC 842120 842827 + 30S ribosomal protein S3 forms a complex with S10 and S14%3B binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation gene gene822 http://www.ncbi.nlm.nih.gov/gene/?term=HI0783 HI0784 HI0784 rplP rplP 842841 843251 + 50S ribosomal protein L16 located in the peptidyl transferase center and may be involved in peptidyl transferase activity%3B similar to archaeal L10e gene gene823 http://www.ncbi.nlm.nih.gov/gene/?term=HI0784 HI0785 HI0785 rpmC rpmC 843251 843442 + 50S ribosomal protein L29 one of the stabilizing components for the large ribosomal subunit gene gene824 http://www.ncbi.nlm.nih.gov/gene/?term=HI0785 HI0786 HI0786 rpsQ rpsQ 843442 843699 + 30S ribosomal protein S17 primary binding protein%3B helps mediate assembly%3B involved in translation fidelity gene gene825 http://www.ncbi.nlm.nih.gov/gene/?term=HI0786 HI0787 HI0787 HI0787 844090 844695 + hypothetical protein gene gene826 http://www.ncbi.nlm.nih.gov/gene/?term=HI0787 HI0788 HI0788 rplN rplN 844976 845347 + 50S ribosomal protein L14 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase gene gene827 http://www.ncbi.nlm.nih.gov/gene/?term=HI0788 HI0789 HI0789 rplX rplX 845358 845669 + 50S ribosomal protein L24 assembly initiator protein%3B binds to 5' end of 23S rRNA and nucleates assembly of the 50S%3B surrounds polypeptide exit tunnel gene gene828 http://www.ncbi.nlm.nih.gov/gene/?term=HI0789 HI0790 HI0790 rplE rplE 845687 846226 + 50S ribosomal protein L5 part of 50S and 5S/L5/L18/L25 subcomplex%3B contacts 5S rRNA and P site tRNA%3B forms a bridge to the 30S subunit in the ribosome by binding to S13 gene gene829 http://www.ncbi.nlm.nih.gov/gene/?term=HI0790 HI0791 HI0791 rpsN rpsN 846238 846543 + 30S ribosomal protein S14 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit%3B similar to what is observed with proteins L31 and L33%2C some proteins in this family contain CXXC motifs that are involved in zinc binding%3B if two copies are present in a genome%2C then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc%3B the proteins in this group do not appear to have the zinc-binding motif gene gene830 http://www.ncbi.nlm.nih.gov/gene/?term=HI0791 HI0792 HI0792 rpsH rpsH 846580 846972 + 30S ribosomal protein S8 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit gene gene831 http://www.ncbi.nlm.nih.gov/gene/?term=HI0792 HI0793 HI0793 rplF rplF 846988 847521 + 50S ribosomal protein L6 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein%3B RNA-binding appears to be in the C-terminal domain%3B mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain%3B it has been localized to a region between the base of the L7/L12 stalk and the central protuberance gene gene832 http://www.ncbi.nlm.nih.gov/gene/?term=HI0793 HI0794 HI0794 rplR rplR 847535 847888 + 50S ribosomal protein L18 binds 5S rRNA along with protein L5 and L25 gene gene833 http://www.ncbi.nlm.nih.gov/gene/?term=HI0794 HI0795 HI0795 rpsE rpsE 847903 848403 + 30S ribosomal protein S5 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body%3B contacts S4 and S8%3B with S4 and S12 plays a role in translational accuracy%3B mutations in this gene result in spectinomycin resistance gene gene834 http://www.ncbi.nlm.nih.gov/gene/?term=HI0795 HI0796 HI0796 rpmD rpmD 848410 848589 + 50S ribosomal protein L30 L30 binds domain II of the 23S rRNA and the 5S rRNA%3B similar to eukaryotic protein L7 gene gene835 http://www.ncbi.nlm.nih.gov/gene/?term=HI0796 HI0797 HI0797 rplO rplO 848593 849027 + 50S ribosomal protein L15 late assembly protein gene gene836 http://www.ncbi.nlm.nih.gov/gene/?term=HI0797 HI0798 HI0798 secY secY 849035 850360 + preprotein translocase subunit SecY forms heterotrimeric complex in the membrane%3B in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG%3B the SecG subunit is not essential%3B in bacteria translocation is driven via the SecA ATPase gene gene837 http://www.ncbi.nlm.nih.gov/gene/?term=HI0798 HI0798.1 HI0798.1 rpmJ rpmJ 850389 850502 + 50S ribosomal protein L36 smallest protein in the large subunit%3B similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc%3B the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion%3B the proteins in this group have the motif gene gene838 http://www.ncbi.nlm.nih.gov/gene/?term=HI0798.1 HI0799 HI0799 rpsM rpsM 850642 851010 + 30S ribosomal protein S13 located at the top of the head of the 30S subunit%2C it contacts several helices of the 16S rRNA%3B makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5%3B contacts P-site tRNA gene gene839 http://www.ncbi.nlm.nih.gov/gene/?term=HI0799 HI0800 HI0800 rpS11 rpS11 851013 851402 + 30S ribosomal protein S11 located on the platform of the 30S subunit%2C it bridges several disparate RNA helices of the 16S rRNA%3B forms part of the Shine-Dalgarno cleft in the 70S ribosome%3B interacts with S7 and S18 and IF-3 gene gene840 http://www.ncbi.nlm.nih.gov/gene/?term=HI0800 HI0801 HI0801 rpsD rpsD 851430 852050 + 30S ribosomal protein S4 primary rRNA binding protein%3B nucleates 30S assembly%3B involved in translational accuracy with proteins S5 and S12%3B interacts with protein S5%3B involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA%3B interacts with transcription complex and functions similar to protein NusA in antitermination gene gene841 http://www.ncbi.nlm.nih.gov/gene/?term=HI0801 HI0802 HI0802 rpoA rpoA 852082 853068 + DNA-directed RNA polymerase subunit alpha catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme gene gene842 http://www.ncbi.nlm.nih.gov/gene/?term=HI0802 HI0803 HI0803 rplQ rplQ 853109 853495 + 50S ribosomal protein L17 is a component of the macrolide binding site in the peptidyl transferase center gene gene843 http://www.ncbi.nlm.nih.gov/gene/?term=HI0803 HI0804 HI0804 HI0804 853622 854216 - gene gene844 http://www.ncbi.nlm.nih.gov/gene/?term=HI0804 HI0805 HI0805 aslB aslB 854335 855035 - gene gene845 http://www.ncbi.nlm.nih.gov/gene/?term=HI0805 HI0806 HI0806 HI0806 855169 855975 + hypothetical protein similar to GB:L77117 SP:Q57883 PID:1591145 gene gene846 http://www.ncbi.nlm.nih.gov/gene/?term=HI0806 HI0807 HI0807 HI0807 856007 857200 - 1-deoxy-D-xylulose 5-phosphate reductoisomerase catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate gene gene847 http://www.ncbi.nlm.nih.gov/gene/?term=HI0807 HI0808 HI0808 frr frr 857310 857867 - ribosome recycling factor Rrf%3B Frr%3B ribosome-recycling factor%3B release factor 4%3B RF4%3B recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G%3B A GTPase-dependent process results in release of 50S from 70S%3B inhibited by release factor RF-1%3B essential for viability%3B structurally similar to tRNAs gene gene848 http://www.ncbi.nlm.nih.gov/gene/?term=HI0808 HI0809 HI0809 pckA pckA 858019 859635 - phosphoenolpyruvate carboxykinase PEP carboxykinase%3B PEP carboxylase%3B PEPCK%3B catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP gene gene849 http://www.ncbi.nlm.nih.gov/gene/?term=HI0809 HI0810 HI0810 hslO hslO 859808 860689 - Hsp33-like chaperonin becomes active under oxidative stress%3B four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive%3B oxidative stress results in oxidized cysteines%2C release of zinc%2C and binding of Hsp33 to aggregation-prone proteins%3B forms dimers and higher order oligomers gene gene850 http://www.ncbi.nlm.nih.gov/gene/?term=HI0810 HI0811 HI0811 argH argH 860834 862207 - argininosuccinate lyase catalyzes the formation of arginine from (N-L-arginino)succinate gene gene851 http://www.ncbi.nlm.nih.gov/gene/?term=HI0811 HI0812 HI0812 galU galU 862342 863229 - glucosephosphate uridylyltransferase similar to GB:M98830 SP:P25520 GB:X59940 PID:146073 PID:42026 gene gene852 http://www.ncbi.nlm.nih.gov/gene/?term=HI0812 HI0813 HI0813 csrA csrA 863251 863442 - carbon storage regulator affects carbohydrate metabolism%3B has regulatory role in many processes gene gene853 http://www.ncbi.nlm.nih.gov/gene/?term=HI0813 HI0814 HI0814 alaS alaS 863520 866144 - alanine--tRNA ligase Catalyzes a two-step reaction%2C first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA gene gene854 http://www.ncbi.nlm.nih.gov/gene/?term=HI0814 HI0815 HI0815 uspA uspA 866332 866757 - universal stress protein A forms asymmetric homodimer%3B similar to GB:U00039 SP:P28242 GB:X67639 PID:43280 PID:466632 gene gene855 http://www.ncbi.nlm.nih.gov/gene/?term=HI0815 HI0816 HI0816 pepP pepP 866859 868151 - aminopeptidase P similar to GB:D00398 SP:P15034 PID:216529 PID:216627 PID:882438 gene gene856 http://www.ncbi.nlm.nih.gov/gene/?term=HI0816 HI0817 HI0817 HI0817 868163 868711 - hypothetical protein the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers%3B function unknown gene gene857 http://www.ncbi.nlm.nih.gov/gene/?term=HI0817 HI0818 HI0818 galM galM 868882 869904 - aldose 1-epimerase catalyzes the conversion of alpha-aldose to the beta-anomer%3B active on D-glucose%2C L-arabinose%2C D-xylose%2C D-galactose%2C maltose and lactose%3B links the metabolism of lactose and galactose gene gene858 http://www.ncbi.nlm.nih.gov/gene/?term=HI0818 HI0819 HI0819 galK galK 869914 871068 - galactokinase catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism gene gene859 http://www.ncbi.nlm.nih.gov/gene/?term=HI0819 HI0820 HI0820 galT galT 871145 872194 - galactose-1-phosphate uridylyltransferase catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P gene gene860 http://www.ncbi.nlm.nih.gov/gene/?term=HI0820 HI0821 HI0821 galR galR 872402 873400 + LacI family transcriptional repressor similar to SP:P31766 GB:X65934 PID:1573834 gene gene861 http://www.ncbi.nlm.nih.gov/gene/?term=HI0821 HI0822 HI0822 mglB mglB 873545 874540 + galactose ABC transporter substrate-binding protein similar to SP:P02927 GB:K00419 GB:X05646 PID:146853 PID:146857 gene gene862 http://www.ncbi.nlm.nih.gov/gene/?term=HI0822 HI0823 HI0823 mglA mglA 874606 876126 + galactose/methyl galaxtoside transporter ATP-binding protein with MglBC transports galactose or methyl galactoside into the cell%3B contains 2 ATP binding domains gene gene863 http://www.ncbi.nlm.nih.gov/gene/?term=HI0823 HI0824 HI0824 mglC mglC 876143 877153 + beta-methylgalactoside transporter inner membrane protein ABC transporter%3B functions in galactose transport%3B part of MglA2C2B transporter complex gene gene864 http://www.ncbi.nlm.nih.gov/gene/?term=HI0824 HI0825 HI0825 HI0825 877299 878033 + hypothetical protein gene gene865 http://www.ncbi.nlm.nih.gov/gene/?term=HI0825 HI0826 HI0826 HI0826 878039 878596 + intracellular septation protein A Involved in cell division%3B probably involved in intracellular septation gene gene866 http://www.ncbi.nlm.nih.gov/gene/?term=HI0826 HI0827 HI0827 HI0827 878596 879060 + acyl-CoA thioesterase similar to GB:K00431 SP:P04379 PID:455187 PID:902382 PID:902391 gene gene867 http://www.ncbi.nlm.nih.gov/gene/?term=HI0827 HI0828 HI0828 HI0828 879077 879373 + hypothetical protein gene gene868 http://www.ncbi.nlm.nih.gov/gene/?term=HI0828 HI0829 HI0829 HI0829 879389 881170 + soluble lytic murein transglycosylase similar to GB:U14003 SP:P03810 GB:M69185 PID:147836 PID:537232 gene gene869 http://www.ncbi.nlm.nih.gov/gene/?term=HI0829 HI0830 HI0830 trpR trpR 881208 881513 + Trp operon repressor When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription gene gene870 http://www.ncbi.nlm.nih.gov/gene/?term=HI0830 HI0831 HI0831 mtgA mtgA 881500 882240 + monofunctional biosynthetic peptidoglycan transglycosylase glycosyltransferase%3B polymerizes glycan strands in the peptidoglycan gene gene871 http://www.ncbi.nlm.nih.gov/gene/?term=HI0831 HI0832 HI0832 frdD frdD 882346 882690 - fumarate reductase subunit D in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane gene gene872 http://www.ncbi.nlm.nih.gov/gene/?term=HI0832 HI0833 HI0833 frdC frdC 882703 883113 - fumarate reductase subunit C part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration%3B FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit%2C respectively%3B FrdCD are the membrane components which interact with quinone and are involved in electron transfer%3B the catalytic subunits are similar to succinate dehydrogenase SdhAB gene gene873 http://www.ncbi.nlm.nih.gov/gene/?term=HI0833 HI0834 HI0834 frdB frdB 883124 883894 - fumarate reductase iron-sulfur subunit part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration%3B FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit%2C respectively%3B FrdCD are the membrane components which interact with quinone and are involved in electron transfer%3B the catalytic subunits are similar to succinate dehydrogenase SdhAB gene gene874 http://www.ncbi.nlm.nih.gov/gene/?term=HI0834 HI0835 HI0835 frdA frdA 883887 885686 - fumarate reductase flavoprotein subunit part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration%3B FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit%2C respectively%3B FrdCD are the membrane components which interact with quinone and are involved in electron transfer%3B the catalytic subunits are similar to succinate dehydrogenase SdhAB gene gene875 http://www.ncbi.nlm.nih.gov/gene/?term=HI0835 HI0836 HI0836 genX genX 885898 886869 + elongation factor P--(R)-beta-lysine ligase gene gene876 http://www.ncbi.nlm.nih.gov/gene/?term=HI0836 HI0837 HI0837 cpxR cpxR 887135 887818 - response regulator similar to GB:L19201 SP:P16244 GB:L14579 GB:X13307 PID:145589 gene gene877 http://www.ncbi.nlm.nih.gov/gene/?term=HI0837 HI0838 HI0838 HI0838 887872 888285 - small protein A similar to SP:P23089 gene gene878 http://www.ncbi.nlm.nih.gov/gene/?term=HI0838 HI0839 HI0839 HI0839 888351 889367 - nucleoid-associated protein NdpA similar to SP:P33920 PID:405914 GB:U00096 PID:1788513 gene gene879 http://www.ncbi.nlm.nih.gov/gene/?term=HI0839 HI0840 HI0840 HI0840 889493 889711 + hypothetical protein similar to SP:P33921 PID:405915 GB:U00096 PID:1788514 gene gene880 http://www.ncbi.nlm.nih.gov/gene/?term=HI0840 HI0841 HI0841 HI0841 889713 891470 + hypothetical protein similar to SP:P33922 PID:453987 GB:U00096 PID:1788515 gene gene881 http://www.ncbi.nlm.nih.gov/gene/?term=HI0841 HI0842 HI0842 HI0842 891668 892659 + gene gene882 http://www.ncbi.nlm.nih.gov/gene/?term=HI0842 HI0844 HI0844 mobA mobA 892798 893376 - molybdopterin-guanine dinucleotide biosynthesis protein MobA in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis gene gene883 http://www.ncbi.nlm.nih.gov/gene/?term=HI0844 HI0845 HI0845 HI0845 893463 893729 + hypothetical protein similar to GB:L19201 SP:P32126 PID:304964 GB:U00096 PID:1790289 gene gene884 http://www.ncbi.nlm.nih.gov/gene/?term=HI0845 HI0846 HI0846 por por 893740 894357 + oxidoreductase similar to GB:M94205 SP:P31810 PID:1573860 gene gene885 http://www.ncbi.nlm.nih.gov/gene/?term=HI0846 HI0847 HI0847 HI0847 894419 894754 + hypothetical protein similar to GB:M87049 SP:P27827 PID:148172 GB:U00096 PID:2367277 gene gene886 http://www.ncbi.nlm.nih.gov/gene/?term=HI0847 HI0848 HI0848 trmA trmA 894898 895989 + tRNA (uracil-5-)-methyltransferase catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs gene gene887 http://www.ncbi.nlm.nih.gov/gene/?term=HI0848 HI0849m HI0849m HI0849m 895971 896744 + SAM-dependent methyltransferase gene gene888 http://www.ncbi.nlm.nih.gov/gene/?term=HI0849m HI0850 HI0850 HI0850 896738 897172 + sigma-E factor regulatory protein similar to SP:P46187 PID:987645 PID:1045631 PID:1050877 GB:U00096 gene gene889 http://www.ncbi.nlm.nih.gov/gene/?term=HI0850 HI0851 HI0851 mobB mobB 897574 898110 + molybdopterin-guanine dinucleotide biosynthesis protein B similar to GB:L19201 SP:P32125 PID:304962 GB:U00096 PID:1790287 gene gene890 http://www.ncbi.nlm.nih.gov/gene/?term=HI0851 HI0852 HI0852 HI0852 898107 899498 + hypothetical protein similar to GB:L10328 SP:P31474 PID:290604 GB:U00096 PID:1790195 gene gene891 http://www.ncbi.nlm.nih.gov/gene/?term=HI0852 HI0853 HI0853 dppA dppA 899639 901288 + heme-binding lipoprotein similar to GB:M84028 SP:P33950 PID:1573869 gene gene892 http://www.ncbi.nlm.nih.gov/gene/?term=HI0853 HI0854 HI0854 HI0854 901464 902225 + heme iron utilization protein similar to GB:AE000511 PID:2313418 gene gene893 http://www.ncbi.nlm.nih.gov/gene/?term=HI0854 HI0855 HI0855 HI0855 902362 902709 - hypothetical protein similar to SP:P42626 PID:606050 GB:U00096 PID:1789496 gene gene894 http://www.ncbi.nlm.nih.gov/gene/?term=HI0855 HI0856 HI0856 polA polA 902724 905516 - DNA polymerase I has 3'-5' exonuclease%2C 5'-3' exonuclease and 5'-3'polymerase activities%2C primarily functions to fill gaps during DNA replication and repair gene gene895 http://www.ncbi.nlm.nih.gov/gene/?term=HI0856 HI0857 HI0857 HI0857 905665 905967 + hypothetical protein similar to SP:P45580 PID:882440 GB:U00096 PID:1789277 gene gene896 http://www.ncbi.nlm.nih.gov/gene/?term=HI0857 HI0857.1 HI0857.1 HI0857.1 906073 906271 + gene gene897 http://www.ncbi.nlm.nih.gov/gene/?term=HI0857.1 HI0858 HI0858 HI0858 906285 906848 + 5-formyltetrahydrofolate cyclo-ligase similar to GB:M12965 SP:P09160 PID:147874 PID:882441 GB:U00096 gene gene898 http://www.ncbi.nlm.nih.gov/gene/?term=HI0858 HI0859 HI0859 clpB clpB 906976 909546 + ATP-dependent Clp protease ATPase subunit similar to GB:M29364 SP:P03815 GB:V00350 GB:X57620 PID:1236633 gene gene899 http://www.ncbi.nlm.nih.gov/gene/?term=HI0859 HI0860 HI0860 HI0860 909583 910323 - 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB Specifically methylates the ribose of guanosine 2251 in 23S rRNA gene gene900 http://www.ncbi.nlm.nih.gov/gene/?term=HI0860 HI0861 HI0861 vacB vacB 910379 912727 - virulence-associated protein exoribonuclease R%3B similar to GB:U14003 SP:P21499 PID:537020 GB:U00096 PID:1790622 gene gene901 http://www.ncbi.nlm.nih.gov/gene/?term=HI0861 HI0862 HI0862 HI0862 912919 913626 - hypothetical protein similar to SP:P37619 PID:466607 GB:U00096 PID:1789882 gene gene902 http://www.ncbi.nlm.nih.gov/gene/?term=HI0862 HI0863 HI0863 pdxH pdxH 913819 914451 + pyridoxamine 5'-phosphate oxidase catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate gene gene903 http://www.ncbi.nlm.nih.gov/gene/?term=HI0863 HI0864 HI0864 HI0864 914539 916389 - GTP-binding protein similar to GB:L19201 SP:P32132 PID:304976 GB:U00096 PID:1790302 gene gene904 http://www.ncbi.nlm.nih.gov/gene/?term=HI0864 HI0865 HI0865 glnA glnA 916620 918038 + glutamine synthetase similar to SP:P28786 GB:X68129 PID:45900 gene gene905 http://www.ncbi.nlm.nih.gov/gene/?term=HI0865 HI0866 HI0866 HI0866 918515 919138 + hypothetical protein gene gene906 http://www.ncbi.nlm.nih.gov/gene/?term=HI0866 HI0867 HI0867 HI0867 919376 920590 + lipopolysaccharide biosynthesis protein similar to SP:P37781 PID:454902 gene gene907 http://www.ncbi.nlm.nih.gov/gene/?term=HI0867 HI0868 HI0868 HI0868 920571 921323 + hypothetical protein similar to GB:AL009126 gene gene908 http://www.ncbi.nlm.nih.gov/gene/?term=HI0868 HI0869 HI0869 HI0869 921289 922214 + gene gene909 http://www.ncbi.nlm.nih.gov/gene/?term=HI0869 HI0871 HI0871 siaA siaA 923293 924213 + N-acetylneuraminic acid synthase-like protein gene gene910 http://www.ncbi.nlm.nih.gov/gene/?term=HI0871 HI0872 HI0872 wbaP wbaP 924206 925621 + undecaprenyl-phosphate galactosephosphotransferase similar to SP:P26406 GB:X52093 PID:1335815 PID:1335817 gene gene911 http://www.ncbi.nlm.nih.gov/gene/?term=HI0872 HI0873 HI0873 rffG rffG 925683 926696 + dTDP-glucose 46-dehydratase similar to GB:M87049 SP:P27830 PID:148191 GB:U00096 PID:1790223 gene gene912 http://www.ncbi.nlm.nih.gov/gene/?term=HI0873 HI0874 HI0874 HI0874 926749 927948 - hypothetical protein gene gene913 http://www.ncbi.nlm.nih.gov/gene/?term=HI0874 HI0875 HI0875 pepB pepB 927931 929402 + gene gene914 http://www.ncbi.nlm.nih.gov/gene/?term=HI0875 HI0876 HI0876 ndk ndk 929409 929834 + nucleoside diphosphate kinase catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate gene gene915 http://www.ncbi.nlm.nih.gov/gene/?term=HI0876 HI0877 HI0877 obgE obgE 929904 931076 - GTPase ObgE essential GTPase%3B exhibits high exchange rate for GTP/GDP%3B associates with 50S ribosomal subunit%3B involved in regulation of chromosomal replication gene gene916 http://www.ncbi.nlm.nih.gov/gene/?term=HI0877 HI0878 HI0878 HI0878 931104 932024 - hypothetical protein similar to SP:P28636 PID:216638 PID:606122 GB:U00096 PID:1789575 gene gene917 http://www.ncbi.nlm.nih.gov/gene/?term=HI0878 HI0879 HI0879 rpmA rpmA 932105 932362 - 50S ribosomal protein L27 involved in the peptidyltransferase reaction during translation gene gene918 http://www.ncbi.nlm.nih.gov/gene/?term=HI0879 HI0880 HI0880 rplU rplU 932383 932694 - 50S ribosomal protein L21 similar to GB:D13267 SP:P02422 PID:216636 PID:606124 GB:U00096 gene gene919 http://www.ncbi.nlm.nih.gov/gene/?term=HI0880 HI0881 HI0881 ispB ispB 932907 933896 + octaprenyl-diphosphate synthase similar to SP:P19641 GB:X68873 PID:388220 PID:606125 GB:U00096 gene gene920 http://www.ncbi.nlm.nih.gov/gene/?term=HI0881 HI0882 HI0882 HI0882 933947 934684 + hypothetical protein gene gene921 http://www.ncbi.nlm.nih.gov/gene/?term=HI0882 HI0883 HI0883 HI0883 934743 936113 - Na+/alanine symporter similar to PID:757741 SP:Q45068 PID:1405464 GB:AL009126 gene gene922 http://www.ncbi.nlm.nih.gov/gene/?term=HI0883 HI0884 HI0884 arcA arcA 936511 937221 - two-component response regulator similar to SP:P03026 GB:L34010 GB:M10044 PID:1790863 gene gene923 http://www.ncbi.nlm.nih.gov/gene/?term=HI0884 HI0885 HI0885 dipZ dipZ 937413 939152 + thiol:disulfide interchange protein two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm%3B DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm gene gene924 http://www.ncbi.nlm.nih.gov/gene/?term=HI0885 HI0886 HI0886 HI0886 939264 939668 + hypothetical protein gene gene925 http://www.ncbi.nlm.nih.gov/gene/?term=HI0886 HI0887 HI0887 purH purH 939856 941454 + bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase involved in de novo purine biosynthesis gene gene926 http://www.ncbi.nlm.nih.gov/gene/?term=HI0887 HI0888 HI0888 purD purD 941550 942839 + phosphoribosylamine--glycine ligase catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis gene gene927 http://www.ncbi.nlm.nih.gov/gene/?term=HI0888 HI0889 HI0889 glyA glyA 942963 944228 + serine hydroxymethyltransferase catalyzes the reaction of glycine with 5%2C10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate gene gene928 http://www.ncbi.nlm.nih.gov/gene/?term=HI0889 HI0890m HI0890m coaE coaE 944299 944919 + dephospho-CoA kinase catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A%3B involved in coenzyme A biosynthesis gene gene929 http://www.ncbi.nlm.nih.gov/gene/?term=HI0890m HI0891m HI0891m HI0891m 944912 945118 + zinc-binding protein gene gene930 http://www.ncbi.nlm.nih.gov/gene/?term=HI0891m HI0892 HI0892 rhlB rhlB 945227 946483 + ATP-dependent RNA helicase RhlB enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome%2C a multi-enzyme complex important in RNA processing and messenger RNA degradation gene gene931 http://www.ncbi.nlm.nih.gov/gene/?term=HI0892 HI0893 HI0893 HI0893 946725 947288 + transcriptional repressor Bm3T1%3B similar to GB:S87512 SP:P43506 PID:623036 PID:247052 gene gene932 http://www.ncbi.nlm.nih.gov/gene/?term=HI0893 HI0894 HI0894 HI0894 947368 948516 + membrane-fusion protein similar to GB:U14993 SP:P43505 PID:438192 PID:550460 gene gene933 http://www.ncbi.nlm.nih.gov/gene/?term=HI0894 HI0895 HI0895 acrB acrB 948516 951614 + acriflavine resistance protein similar to GB:M94248 SP:P31224 GB:U00734 PID:290406 PID:532311 gene gene934 http://www.ncbi.nlm.nih.gov/gene/?term=HI0895 HI0896 HI0896 ftsN ftsN 952004 952618 + cell division protein similar to GB:L19201 SP:P29131 GB:L14281 PID:290448 PID:305036 gene gene935 http://www.ncbi.nlm.nih.gov/gene/?term=HI0896 HI0897 HI0897 emrB emrB 952635 954167 - multidrug resistance protein B similar to GB:M86657 SP:P27304 PID:145836 GB:U00096 PID:1789042 gene gene936 http://www.ncbi.nlm.nih.gov/gene/?term=HI0897 HI0898 HI0898 emrA emrA 954177 955349 - multidrug resistance protein A similar to GB:M86657 SP:P27303 PID:145835 GB:U00096 PID:1789041 gene gene937 http://www.ncbi.nlm.nih.gov/gene/?term=HI0898 HI0899 HI0899 folA folA 955532 956014 - dihydrofolate reductase similar to GB:D10483 SP:P00379 GB:J01609 GB:J01609 GB:X05108 gene gene938 http://www.ncbi.nlm.nih.gov/gene/?term=HI0899 HI0900 HI0900 proB proB 956115 957221 + gamma-glutamyl kinase catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis gene gene939 http://www.ncbi.nlm.nih.gov/gene/?term=HI0900 HI0901 HI0901 HI0901 957302 957892 + dinucleoside polyphosphate hydrolase hydrolyzes diadenosine polyphosphate gene gene940 http://www.ncbi.nlm.nih.gov/gene/?term=HI0901 HI0902 HI0902 HI0902 957892 958686 + hypothetical protein similar to GB:L77117 SP:Q57883 PID:1591145 gene gene941 http://www.ncbi.nlm.nih.gov/gene/?term=HI0902 HI0904 HI0904 lgt lgt 958695 959501 + prolipoprotein diacylglyceryl transferase transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein gene gene942 http://www.ncbi.nlm.nih.gov/gene/?term=HI0904 HI0905 HI0905 thyA thyA 959511 960362 + thymidylate synthase ThyA%3B catalyzes formation of dTMP and 7%2C8-dihydrofolate from 5%2C10-methylenetetrahydrofolate and dUMP%3B involved in deoxyribonucleotide biosynthesis%3B there are 2 copies in some Bacilli%2C one of which appears to be phage-derived gene gene943 http://www.ncbi.nlm.nih.gov/gene/?term=HI0905 HI0906 HI0906 HI0906 960362 960883 + hypothetical protein similar to SP:P30134 PID:296183 PID:987637 PID:1033148 GB:U00096 gene gene944 http://www.ncbi.nlm.nih.gov/gene/?term=HI0906 HI0907 HI0907 HI0907 960911 961225 - hypothetical protein gene gene945 http://www.ncbi.nlm.nih.gov/gene/?term=HI0907 HI0908 HI0908 HI0908 961305 961607 + hypothetical protein gene gene946 http://www.ncbi.nlm.nih.gov/gene/?term=HI0908 HI0909 HI0909 secA secA 961732 964437 + preprotein translocase subunit SecA functions in protein export%3B can interact with acidic membrane phospholipids and the SecYEG protein complex%3B binds to preproteins%3B binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein%3B ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane%3B additional proteins SecD/F/YajC aid SecA recycling%3B exists in an equilibrium between monomers and dimers%3B may possibly form higher order oligomers%3B proteins in this cluster correspond SecA1%3B SecA2 is not essential and seems to play a role in secretion of a subset of proteins gene gene947 http://www.ncbi.nlm.nih.gov/gene/?term=HI0909 HI0910 HI0910 mutT mutT 964502 964912 + 8-oxo-dGTP diphosphatase MutT%3B similar to GB:D10483 SP:P08337 GB:M20791 GB:X04831 PID:147795 gene gene948 http://www.ncbi.nlm.nih.gov/gene/?term=HI0910 HI0911 HI0911 kefC kefC 965021 966877 + glutathione-regulated potassium efflux system protein similar to GB:D10483 SP:P03819 GB:X56742 PID:216472 PID:41875 gene gene949 http://www.ncbi.nlm.nih.gov/gene/?term=HI0911 HI0912 HI0912 HI0912 966978 967742 + hypothetical protein gene gene950 http://www.ncbi.nlm.nih.gov/gene/?term=HI0912 HI0913 HI0913 rpsB rpsB 967920 968642 + 30S ribosomal protein S2 one of the last subunits in the assembly of the 30S subunit%3B absence of S2 does not inhibit assembly but results in an inactive subunit gene gene951 http://www.ncbi.nlm.nih.gov/gene/?term=HI0913 HI0914 HI0914 tsf tsf 968775 969626 + elongation factor Ts EF-Ts%3B functions during elongation stage of protein translation%3B forms a dimer%3B associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu gene gene952 http://www.ncbi.nlm.nih.gov/gene/?term=HI0914 HI0915 HI0915 lpxD lpxD 969806 970831 - UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis gene gene953 http://www.ncbi.nlm.nih.gov/gene/?term=HI0915 HI0916 HI0916 HI0916 970844 971437 - outer membrane protein similar to PID:1935023 gene gene954 http://www.ncbi.nlm.nih.gov/gene/?term=HI0916 HI0917 HI0917 HI0917 971545 973932 - protective surface antigen D15 similar to GB:U13961 PID:1573938 PID:2231192 PID:2231195 gene gene955 http://www.ncbi.nlm.nih.gov/gene/?term=HI0917 HI0918 HI0918 HI0918 973952 975283 - hypothetical protein similar to SP:P37764 PID:1208948 GB:U00096 PID:1552753 PID:1786373 gene gene956 http://www.ncbi.nlm.nih.gov/gene/?term=HI0918 HI0919 HI0919 cdsA cdsA 975293 976159 - CDP-diglyceride synthetase similar to GB:M11330 SP:P06466 PID:1208947 PID:145476 GB:U00096 gene gene957 http://www.ncbi.nlm.nih.gov/gene/?term=HI0919 HI0920 HI0920 HI0920 976177 976896 - hypothetical protein similar to PID:1208946 GB:U00096 SP:Q47675 PID:1552751 PID:1786371 gene gene958 http://www.ncbi.nlm.nih.gov/gene/?term=HI0920 HI0921 HI0921 leuS leuS 977145 979730 + leucine--tRNA ligase leucine--tRNA ligase%3B LeuRS%3B class-I aminoacyl-tRNA synthetase%3B charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA%3B due to the large number of codons that tRNA(Leu) recognizes%2C the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA%2C but instead recognition is dependent on a conserved discriminator base A37 and a long arm%3B an editing domain hydrolyzes misformed products%3B in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase gene gene959 http://www.ncbi.nlm.nih.gov/gene/?term=HI0921 HI0922 HI0922 HI0922 979825 980328 + rare lipoprotein B similar to GB:M18277 SP:P10101 PID:147663 GB:U00096 PID:1651268 gene gene960 http://www.ncbi.nlm.nih.gov/gene/?term=HI0922 HI0923 HI0923 holA holA 980328 981362 + DNA polymerase III subunit delta required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA gene gene961 http://www.ncbi.nlm.nih.gov/gene/?term=HI0923 HI0923.1 HI0923.1 HI0923.1 981435 981511 - tRNA-Met tRNA gene962 http://www.ncbi.nlm.nih.gov/gene/?term=HI0923.1 HI0924 HI0924 glyS glyS 981597 983663 - glycine--tRNA ligase subunit beta glycine--tRNA ligase beta chain%3B glyS%3B class II aminoacyl tRNA synthetase%3B tetramer of alpha(2)beta(2)%3B catalyzes a two-step reaction%3B first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP%3B second by transfer of the aminoacyl-adenylate to its tRNA gene gene963 http://www.ncbi.nlm.nih.gov/gene/?term=HI0924 HI0925 HI0925 HI0925 984000 984365 - hypothetical protein similar to SP:P45736 GB:U00096 PID:1279405 PID:1787546 gene gene964 http://www.ncbi.nlm.nih.gov/gene/?term=HI0925 HI0926 HI0926 HI0926 984395 984655 - hypothetical protein gene gene965 http://www.ncbi.nlm.nih.gov/gene/?term=HI0926 HI0927 HI0927 glyQ glyQ 984714 985622 - glycine--tRNA ligase subunit alpha glycine--tRNA ligase alpha chain%3B GlyRS%3B class II aminoacyl tRNA synthetase%3B tetramer of alpha(2)beta(2)%3B catalyzes a two-step reaction%3B first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP%3B second by transfer of the aminoacyl-adenylate to its tRNA gene gene966 http://www.ncbi.nlm.nih.gov/gene/?term=HI0927 HI0928 HI0928 hktE hktE 985888 987414 + catalase similar to GB:U02682 PID:1573949 gene gene967 http://www.ncbi.nlm.nih.gov/gene/?term=HI0928 HI0929 HI0929 HI0929 987646 988827 - hypothetical protein similar to GB:M77129 SP:P24196 PID:146678 PID:882568 GB:U00096 gene gene968 http://www.ncbi.nlm.nih.gov/gene/?term=HI0929 HI0930 HI0930 HI0930 988828 989448 - hypothetical protein gene gene969 http://www.ncbi.nlm.nih.gov/gene/?term=HI0930 HI0931 HI0931 HI0931 989421 989840 - hypothetical protein gene gene970 http://www.ncbi.nlm.nih.gov/gene/?term=HI0931 HI0932 HI0932 eno eno 989924 991234 - phosphopyruvate hydratase enolase%3B catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis gene gene971 http://www.ncbi.nlm.nih.gov/gene/?term=HI0932 HI0933 HI0933 HI0933 991355 992560 - hypothetical protein similar to SP:P37631 PID:912464 GB:U00096 PID:2367234 gene gene972 http://www.ncbi.nlm.nih.gov/gene/?term=HI0933 HI0934 HI0934 nrfF nrfF 992557 993711 - cytochrome C-type biogenesis protein similar to SP:P32711 GB:X72298 PID:396410 PID:404307 GB:U00096 gene gene973 http://www.ncbi.nlm.nih.gov/gene/?term=HI0934 HI0935 HI0935 dsbE dsbE 993708 994238 - thiol-disulfide interchange protein similar to SP:P33926 PID:405920 GB:U00096 PID:1788523 gene gene974 http://www.ncbi.nlm.nih.gov/gene/?term=HI0935 HI0936 HI0936 HI0936 994238 996145 - cytochrome C-type biogenesis protein similar to SP:P32710 GB:X72298 PID:581146 GB:U00096 PID:1790511 gene gene975 http://www.ncbi.nlm.nih.gov/gene/?term=HI0936 HI0937 HI0937 suhB suhB 996254 997057 - extragenic suppressor similar to GB:M34828 SP:P22783 PID:147899 GB:U00096 PID:1788882 gene gene976 http://www.ncbi.nlm.nih.gov/gene/?term=HI0937 HI0938 HI0938 HI0938 997258 997770 + hypothetical protein gene gene977 http://www.ncbi.nlm.nih.gov/gene/?term=HI0938 HI0939 HI0939 HI0939 997770 998486 + hypothetical protein gene gene978 http://www.ncbi.nlm.nih.gov/gene/?term=HI0939 HI0940 HI0940 HI0940 998486 999169 + hypothetical protein gene gene979 http://www.ncbi.nlm.nih.gov/gene/?term=HI0940 HI0941 HI0941 HI0941 999144 999449 + hypothetical protein gene gene980 http://www.ncbi.nlm.nih.gov/gene/?term=HI0941 HI0942 HI0942 recC recC 999495 1002860 + exodeoxyribonuclease V subunit gamma similar to SP:P07648 PID:42689 PID:882714 GB:U00096 PID:1789186 gene gene981 http://www.ncbi.nlm.nih.gov/gene/?term=HI0942 HI0943 HI0943 nrdR nrdR 1002915 1003364 + transcriptional regulator NrdR similar to SP:P25538 GB:X64395 PID:42148 GB:U00096 PID:1773097 gene gene982 http://www.ncbi.nlm.nih.gov/gene/?term=HI0943 HI0944 HI0944 ribD ribD 1003367 1004485 + riboflavin biosynthesis protein similar to SP:P25539 GB:X64395 PID:581147 GB:U00096 PID:1773098 gene gene983 http://www.ncbi.nlm.nih.gov/gene/?term=HI0944 HI0945 HI0945 degS degS 1004486 1005508 + protease similar to SP:P31137 GB:U15661 GB:U00096 PID:1789630 gene gene984 http://www.ncbi.nlm.nih.gov/gene/?term=HI0945 HI0946 HI0946 fpg fpg 1005582 1006397 - formamidopyrimidine-DNA glycosylase Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases gene gene985 http://www.ncbi.nlm.nih.gov/gene/?term=HI0946 HI0946.1 HI0946.1 HI0946.1 1006630 1008165 - L-24-diaminobutyrate decarboxylase similar to PID:893355 gene gene986 http://www.ncbi.nlm.nih.gov/gene/?term=HI0946.1 HI0947 HI0947 vapC vapC 1008185 1008583 - virulence-associated protein C similar to GB:L22308 GB:L31763 GB:M74565 PID:145068 PID:438534 gene gene987 http://www.ncbi.nlm.nih.gov/gene/?term=HI0947 HI0948 HI0948 HI0948 1008583 1008816 - hypothetical protein similar to SP:P18355 gene gene988 http://www.ncbi.nlm.nih.gov/gene/?term=HI0948 HI0949 HI0949 HI0949 1008963 1010327 - diaminobutyrate--2-oxoglutarate aminotransferase catalyzes the reversible formation of diaminobutyrate and 2-oxoglutarate from glutamate and L-aspartic beta-semialdehyde gene gene989 http://www.ncbi.nlm.nih.gov/gene/?term=HI0949 HI0950 HI0950 rpmG rpmG 1010675 1010845 - 50S ribosomal protein L33 in Escherichia coli BM108%2C a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function%3B there are paralogous genes in several bacterial genomes%2C and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31%3B the proteins in this group lack the CXXC motif gene gene990 http://www.ncbi.nlm.nih.gov/gene/?term=HI0950 HI0951 HI0951 rpmB rpmB 1010857 1011093 - 50S ribosomal protein L28 required for 70S ribosome assembly gene gene991 http://www.ncbi.nlm.nih.gov/gene/?term=HI0951 HI0952 HI0952 radC radC 1011307 1011972 - DNA repair protein RadC Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase gene gene992 http://www.ncbi.nlm.nih.gov/gene/?term=HI0952 HI0953 HI0953 dfp dfp 1012136 1013338 + bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine%2C which is then decarboxylated to form 4'-phosphopantotheine gene gene993 http://www.ncbi.nlm.nih.gov/gene/?term=HI0953 HI0954 HI0954 dut dut 1013386 1013841 + deoxyuridine 5'-triphosphate nucleotidohydrolase catalyzes the formation of dUMP from dUTP gene gene994 http://www.ncbi.nlm.nih.gov/gene/?term=HI0954 HI0955 HI0955 slmA slmA 1013845 1014501 + nucleoid occlusion protein FtsZ binding protein%3B synthetically lethal with a defect in the Min system%3B this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly gene gene995 http://www.ncbi.nlm.nih.gov/gene/?term=HI0955 HI0956 HI0956 HI0956 1014523 1014775 + gene gene996 http://www.ncbi.nlm.nih.gov/gene/?term=HI0956 HI0957 HI0957 crp crp 1014760 1015434 + cAMP-regulatory protein complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons gene gene997 http://www.ncbi.nlm.nih.gov/gene/?term=HI0957 HI0958 HI0958 rumB rumB 1015799 1016977 - 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC RNA uridine methyltransferase B%3B catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA gene gene998 http://www.ncbi.nlm.nih.gov/gene/?term=HI0958 HI0959 HI0959 exoII exoII 1016970 1018025 - beta-hexosaminidase hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides gene gene999 http://www.ncbi.nlm.nih.gov/gene/?term=HI0959 HI0960 HI0960 HI0960 1018029 1018379 - hypothetical protein gene gene1000 http://www.ncbi.nlm.nih.gov/gene/?term=HI0960 HI0961 HI0961 HI0961 1018379 1018729 - HIT-like protein similar to SP:P44956 gene gene1001 http://www.ncbi.nlm.nih.gov/gene/?term=HI0961 HI0962 HI0962 ileS ileS 1018846 1021671 - gene gene1002 http://www.ncbi.nlm.nih.gov/gene/?term=HI0962 HI0963 HI0963 ribF ribF 1021700 1022638 - bifunctional riboflavin kinase/FMN adenylyltransferase catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN%3B in Bacillus the ribC gene has both flavokinase and FAD synthetase activities gene gene1003 http://www.ncbi.nlm.nih.gov/gene/?term=HI0963 HI0964 HI0964 mviN mviN 1022673 1024205 - virulence factor similar to GB:D25292 SP:P37169 GB:Z26133 PID:438252 PID:505363 gene gene1004 http://www.ncbi.nlm.nih.gov/gene/?term=HI0964 HI0965 HI0965 rpsT rpsT 1024514 1024777 + 30S ribosomal protein S20 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase gene gene1005 http://www.ncbi.nlm.nih.gov/gene/?term=HI0965 HI0966 HI0966 HI0966 1024850 1025416 - hypothetical protein gene gene1006 http://www.ncbi.nlm.nih.gov/gene/?term=HI0966 HI0967 HI0967 HI0967 1025442 1025546 + hypothetical protein gene gene1007 http://www.ncbi.nlm.nih.gov/gene/?term=HI0967 HI0968 HI0968 menB menB 1025562 1026419 + 1%2C4-dihydroxy-2-naphthoyl-CoA synthase catalyzes the formation of 1%2C4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA gene gene1008 http://www.ncbi.nlm.nih.gov/gene/?term=HI0968 HI0969 HI0969 menC menC 1026452 1027477 + O-succinylbenzoate synthase catalyzes the dehydration of 2-succinyl-6-hydroxy-2%2C4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate gene gene1009 http://www.ncbi.nlm.nih.gov/gene/?term=HI0969 HI0970 HI0970 aroQ aroQ 1027535 1027984 + 3-dehydroquinate dehydratase catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis gene gene1010 http://www.ncbi.nlm.nih.gov/gene/?term=HI0970 HI0971 HI0971 accB accB 1028137 1028604 + acetyl-CoA carboxylase biotin carboxyl carrier protein subunit composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex%2C the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA%2C which in turn controls the rate of fatty acid metabolism gene gene1011 http://www.ncbi.nlm.nih.gov/gene/?term=HI0971 HI0972 HI0972 accC accC 1028779 1030125 + acetyl-CoA carboxylase biotin carboxylase subunit an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase%2C an enzyme that catalyzes the formation of malonyl-CoA%2C which in turn controls the rate of fatty acid metabolism gene gene1012 http://www.ncbi.nlm.nih.gov/gene/?term=HI0972 HI0973 HI0973 HI0973 1030275 1031144 + hypothetical protein gene gene1013 http://www.ncbi.nlm.nih.gov/gene/?term=HI0973 HI0974.1 HI0974.1 HI0974.1 1032765 1033022 + hypothetical protein similar to SP:P45566 PID:606197 GB:U00096 PID:1789655 gene gene1015 http://www.ncbi.nlm.nih.gov/gene/?term=HI0974.1 HI0974m HI0974m HI0974m 1031208 1032653 + gene gene1014 http://www.ncbi.nlm.nih.gov/gene/?term=HI0974m HI0975 HI0975 panF panF 1033019 1034473 + sodium/panthothenate symporter mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions%3B member of SSS family of sodium/solute symporters%3B the imported panthothenate is phosphorylated by panthothenate kinase gene gene1016 http://www.ncbi.nlm.nih.gov/gene/?term=HI0975 HI0976 HI0976 HI0976 1034593 1035464 + gene gene1017 http://www.ncbi.nlm.nih.gov/gene/?term=HI0976 HI0977 HI0977 fic fic 1035466 1036041 + adenosine monophosphate-protein transferase similar to GB:M28363 SP:P20605 PID:145955 PID:147054 PID:606295 gene gene1018 http://www.ncbi.nlm.nih.gov/gene/?term=HI0977 HI0978 HI0978 prmA prmA 1036082 1036972 + ribosomal protein L11 methyltransferase methylates ribosomal protein L11 at multiple amino acid positions%3B mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype gene gene1019 http://www.ncbi.nlm.nih.gov/gene/?term=HI0978 HI0979 HI0979 HI0979 1037121 1038113 + hypothetical protein similar to SP:P45672 PID:599600 gene gene1020 http://www.ncbi.nlm.nih.gov/gene/?term=HI0979 HI0980 HI0980 fis fis 1038094 1038393 + DNA-binding protein Fis Stimulates excision of phage lambda%3B affects Mu development%3B acts as an activator of rRNA and iRNA transcription gene gene1021 http://www.ncbi.nlm.nih.gov/gene/?term=HI0980 HI0981 HI0981 smpB smpB 1038488 1038973 - SsrA-binding protein binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes%3B also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site%3B SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus%3B both the tmRNA and SmpB are regulated in cell cycle-dependent manner%3B functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation gene gene1022 http://www.ncbi.nlm.nih.gov/gene/?term=HI0981 HI0982 HI0982 pfkA pfkA 1039212 1040177 - 6-phosphofructokinase catalyzes the formation of D-fructose 1%2C6-bisphosphate from D-fructose 6-phosphate in glycolysis gene gene1023 http://www.ncbi.nlm.nih.gov/gene/?term=HI0982 HI0983 HI0983 HI0983 1040273 1040854 - hypothetical protein gene gene1024 http://www.ncbi.nlm.nih.gov/gene/?term=HI0983 HI0984 HI0984 HI0984 1040847 1041623 - hypothetical protein similar to GB:D10483 SP:P11288 PID:216438 PID:537248 PID:1128976 gene gene1025 http://www.ncbi.nlm.nih.gov/gene/?term=HI0984 HI0985 HI0985 dprA dprA 1041677 1042798 - DNA processing chain A similar to GB:L42023 SP:P43862 PID:1006171 PID:1221098 PID:609332 gene gene1026 http://www.ncbi.nlm.nih.gov/gene/?term=HI0985 HI0986 HI0986 leuA leuA 1043355 1044902 + 2-isopropylmalate synthase catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis gene gene1027 http://www.ncbi.nlm.nih.gov/gene/?term=HI0986 HI0987 HI0987 leuB leuB 1044988 1046064 + 3-isopropylmalate dehydrogenase catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis gene gene1028 http://www.ncbi.nlm.nih.gov/gene/?term=HI0987 HI0988 HI0988 leuC leuC 1046240 1047649 + isopropylmalate isomerase large subunit dehydratase component%2C catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate gene gene1029 http://www.ncbi.nlm.nih.gov/gene/?term=HI0988 HI0989 HI0989 leuD leuD 1047673 1048275 + 3-isopropylmalate dehydratase small subunit catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis%3B forms a heterodimer of LeuC/D gene gene1030 http://www.ncbi.nlm.nih.gov/gene/?term=HI0989 HI0990 HI0990 iga1 iga1 1048389 1053473 - immunoglobin A1 protease similar to GB:M87489 gene gene1031 http://www.ncbi.nlm.nih.gov/gene/?term=HI0990 HI0991 HI0991 recF recF 1053715 1054794 - recombination protein F Required for DNA replication%3B binds preferentially to single-stranded%2C linear DNA gene gene1032 http://www.ncbi.nlm.nih.gov/gene/?term=HI0991 HI0992 HI0992 dnaN dnaN 1054796 1055896 - DNA polymerase III subunit beta binds the polymerase to DNA and acts as a sliding clamp gene gene1033 http://www.ncbi.nlm.nih.gov/gene/?term=HI0992 HI0993 HI0993 dnaA dnaA 1055909 1057273 - chromosomal replication initiation protein binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication%3B can also affect transcription of multiple genes including itself. gene gene1034 http://www.ncbi.nlm.nih.gov/gene/?term=HI0993 HI0994 HI0994 tbp1 tbp1 1057465 1060203 - transferrin-binding protein 1 similar to GB:Z15129 SP:Q06987 GB:S64486 GB:X75168 PID:297044 gene gene1035 http://www.ncbi.nlm.nih.gov/gene/?term=HI0994 HI0995 HI0995 tbp2 tbp2 1060231 1062108 - transferrin-binding protein 2 similar to PID:1177569 gene gene1036 http://www.ncbi.nlm.nih.gov/gene/?term=HI0995 HI0997m HI0997m HI0997m 1062206 1063651 + gene gene1037 http://www.ncbi.nlm.nih.gov/gene/?term=HI0997m HI0998 HI0998 rpmH rpmH 1063832 1063966 + 50S ribosomal protein L34 in Escherichia coli transcription of this gene is enhanced by polyamines gene gene1038 http://www.ncbi.nlm.nih.gov/gene/?term=HI0998 HI0999 HI0999 rnpA rnpA 1063986 1064345 + ribonuclease P protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus%3B this enzyme also cleaves other RNA substrates gene gene1039 http://www.ncbi.nlm.nih.gov/gene/?term=HI0999 HI1000 HI1000 HI1000 1064309 1064569 + hypothetical protein similar to PID:1005414 gene gene1040 http://www.ncbi.nlm.nih.gov/gene/?term=HI1000 HI1001 HI1001 yidC yidC 1064569 1066194 + inner membrane protein translocase component YidC functions to insert inner membrane proteins into the IM in Escherichia coli%3B interacts with transmembrane segments%3B functions in both Sec-dependent and -independent membrane insertion%3B similar to Oxa1p in mitochondria gene gene1041 http://www.ncbi.nlm.nih.gov/gene/?term=HI1001 HI1002 HI1002 trmE trmE 1066325 1067710 + tRNA modification GTPase TrmE in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine%2C which is found in the wobble position of some tRNAs and affects ribosomal frameshifting%3B shows potassium-dependent dimerization and GTP hydrolysis%3B also involved in regulation of glutamate-dependent acid resistance and activation of gadE gene gene1042 http://www.ncbi.nlm.nih.gov/gene/?term=HI1002 HI1003.4 HI1003.4 tRNA-Glu-1 tRNA-Glu-1 126969 127044 - tRNA-Glu tRNA gene119 http://www.ncbi.nlm.nih.gov/gene/?term=HI1003.4 HI1003.5 HI1003.5 HIrrnE16S HIrrnE16S 127172 128720 - 16S ribosomal RNA rRNA gene120 http://www.ncbi.nlm.nih.gov/gene/?term=HI1003.5 HI1004 HI1004 HI1004 1067898 1069767 + peptidyl-prolyl cis-trans isomerase contains frameshifts%3B similar to GB:U00096 SP:P77241 PID:1580712 PID:1773125 PID:1786645 gene gene1043 http://www.ncbi.nlm.nih.gov/gene/?term=HI1004 HI10044.1 HI10044.1 HI10044.1 47152 47241 + tRNA-Ser tRNA gene44 http://www.ncbi.nlm.nih.gov/gene/?term=HI10044.1 HI1005 HI1005 HI1005 1069855 1071414 + hypothetical protein similar to HI1064%3B similar to GB:U00096 SP:P75785 PID:1787035 gene gene1044 http://www.ncbi.nlm.nih.gov/gene/?term=HI1005 HI1006 HI1006 lspA lspA 1071484 1071999 + lipoprotein signal peptidase lipoprotein signal peptidase%3B integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis gene gene1045 http://www.ncbi.nlm.nih.gov/gene/?term=HI1006 HI1007 HI1007 ispH ispH 1071996 1072940 + 4-hydroxy-3-methylbut-2-enyl diphosphate reductase catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP)%3B functions in the nonmevalonate isoprenoid biosynthesis pathway gene gene1046 http://www.ncbi.nlm.nih.gov/gene/?term=HI1007 HI1008 HI1008 HI1008 1073118 1073456 + hypothetical protein similar to GB:U00096 SP:P77415 PID:1580713 PID:1773126 PID:1786646 gene gene1047 http://www.ncbi.nlm.nih.gov/gene/?term=HI1008 HI1009 HI1009 glpR glpR 1073504 1074274 - glycerol-3-phosphate regulon repressor similar to SP:P09392 GB:M96795 PID:146186 PID:606358 GB:U00096 gene gene1048 http://www.ncbi.nlm.nih.gov/gene/?term=HI1009 HI1010 HI1010 HI1010 1074433 1075338 + 3-hydroxyisobutyrate dehydrogenase similar to PID:882629 GB:U00096 PID:1789092 gene gene1049 http://www.ncbi.nlm.nih.gov/gene/?term=HI1010 HI1011 HI1011 HI1011 1075341 1076582 + hypothetical protein similar to PID:882630 GB:U00096 PID:1789093 gene gene1050 http://www.ncbi.nlm.nih.gov/gene/?term=HI1011 HI1012 HI1012 HI1012 1076579 1077211 + aldolase similar to PID:882631 GB:U00096 SP:Q46890 PID:1789094 gene gene1051 http://www.ncbi.nlm.nih.gov/gene/?term=HI1012 HI1013 HI1013 HI1013 1077214 1077990 + hypothetical protein similar to PID:882632 GB:U00096 SP:Q46891 PID:1789095 gene gene1052 http://www.ncbi.nlm.nih.gov/gene/?term=HI1013 HI1014 HI1014 HI1014 1078046 1078993 + hypothetical protein similar to PID:695275 gene gene1053 http://www.ncbi.nlm.nih.gov/gene/?term=HI1014 HI1015 HI1015 gntP gntP 1079002 1080468 + gluconate permease similar to SP:P39835 PID:606350 GB:U00096 PID:1789820 gene gene1054 http://www.ncbi.nlm.nih.gov/gene/?term=HI1015 HI1016 HI1016 HI1016 1080488 1080916 + hypothetical protein gene gene1055 http://www.ncbi.nlm.nih.gov/gene/?term=HI1016 HI1017 HI1017 glpF glpF 1081154 1081795 + gene gene1056 http://www.ncbi.nlm.nih.gov/gene/?term=HI1017 HI1018 HI1018 HI1018 1081941 1082514 - this region contains an authentic frame shift and is not the result of a sequencing artifact%3B similar to GB:X59756 gene gene1057 http://www.ncbi.nlm.nih.gov/gene/?term=HI1018 HI1019 HI1019 tbpA tbpA 1082773 1083771 + thiamin ABC transporter substrate-binding protein similar to GB:D10483 SP:P31550 GB:U09984 PID:216488 PID:497658 gene gene1058 http://www.ncbi.nlm.nih.gov/gene/?term=HI1019 HI1020 HI1020 thiP thiP 1083776 1085392 + thiamine transporter membrane protein permease%3B with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell%3B repressed in presence of exogenous thiamine gene gene1059 http://www.ncbi.nlm.nih.gov/gene/?term=HI1020 HI1021 HI1021 HI1021 1085376 1086023 + thiamin ABC transporter ATP-binding protein similar to GB:D10483 SP:P31548 PID:216486 GB:U00096 PID:1786253 gene gene1060 http://www.ncbi.nlm.nih.gov/gene/?term=HI1021 HI1022 HI1022 bioB bioB 1086136 1087137 + biotin synthetase similar to GB:J04423 SP:P12996 PID:145425 PID:490219 GB:U00096 gene gene1061 http://www.ncbi.nlm.nih.gov/gene/?term=HI1022 HI1023 HI1023 tktA tktA 1087262 1089259 - transketolase catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate%3B can transfer ketol groups between several groups%3B in Escherichia coli there are two tkt genes%2C tktA expressed during exponential growth and the tktB during stationary phase gene gene1062 http://www.ncbi.nlm.nih.gov/gene/?term=HI1023 HI1024 HI1024 ulaD ulaD 1089388 1090065 - 3-keto-L-gulonate-6-phosphate decarboxylase catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization gene gene1063 http://www.ncbi.nlm.nih.gov/gene/?term=HI1024 HI1025 HI1025 sgbE sgbE 1090115 1090810 - L-ribulose-5-phosphate 4-epimerase catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate%3B links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source gene gene1064 http://www.ncbi.nlm.nih.gov/gene/?term=HI1025 HI1026 HI1026 HI1026 1090804 1091664 - L-xylulose 5-phosphate 3-epimerase L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated%3B may be involved in the utilization of 2%2C3-diketo-L-gulonate gene gene1065 http://www.ncbi.nlm.nih.gov/gene/?term=HI1026 HI1027 HI1027 lyx lyx 1091678 1093135 - L-xylulose kinase similar to SP:P37677 PID:466718 GB:U00096 PID:1790005 gene gene1066 http://www.ncbi.nlm.nih.gov/gene/?term=HI1027 HI1028 HI1028 HI1028 1093194 1094180 - hypothetical protein similar to SP:P37676 PID:466717 GB:U00096 PID:1790004 gene gene1067 http://www.ncbi.nlm.nih.gov/gene/?term=HI1028 HI1029 HI1029 HI1029 1094211 1095488 - hypothetical protein similar to SP:P37675 PID:466716 GB:U00096 PID:1790003 gene gene1068 http://www.ncbi.nlm.nih.gov/gene/?term=HI1029 HI1030 HI1030 HI1030 1095485 1095970 - hypothetical protein similar to SP:P37674 PID:466715 GB:U00096 PID:1790002 gene gene1069 http://www.ncbi.nlm.nih.gov/gene/?term=HI1030 HI1031 HI1031 HI1031 1096042 1097040 - 2%2C3-diketo-L-gulonate reductase NAD(P)H-dependent%3B catalyzes the reduction of 2%2C3-diketo-L-gulonate to 3-keto-L-gulonate gene gene1070 http://www.ncbi.nlm.nih.gov/gene/?term=HI1031 HI1032 HI1032 HI1032 1097216 1098022 + transcriptional regulator similar to SP:P37671 PID:466712 GB:U00096 PID:1789999 gene gene1071 http://www.ncbi.nlm.nih.gov/gene/?term=HI1032 HI1033 HI1033 serB serB 1098172 1099116 + phosphoserine phosphatase catalyzes the formation of serine from O-phosphoserine gene gene1072 http://www.ncbi.nlm.nih.gov/gene/?term=HI1033 HI1034 HI1034 HI1034 1099134 1099625 + nucleotide-binding protein nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ%3B the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription gene gene1073 http://www.ncbi.nlm.nih.gov/gene/?term=HI1034 HI1035 HI1035 corA corA 1099920 1100867 + magnesium/nickel/cobalt transporter CorA responsible for the influx of magnesium ions gene gene1074 http://www.ncbi.nlm.nih.gov/gene/?term=HI1035 HI1036 HI1036 HI1036 1100867 1101412 + hypothetical protein similar to PID:801880 SP:P52059 PID:801882 gene gene1075 http://www.ncbi.nlm.nih.gov/gene/?term=HI1036 HI1037 HI1037 HI1037 1101593 1102477 - hypothetical protein similar to PID:984579 GB:U00096 SP:Q47147 PID:1552793 PID:1786417 gene gene1076 http://www.ncbi.nlm.nih.gov/gene/?term=HI1037 HI1038 HI1038 HI1038 1102856 1104058 + hypothetical protein similar to GB:L77117 PID:1592175 gene gene1077 http://www.ncbi.nlm.nih.gov/gene/?term=HI1038 HI1040 HI1040 ureF ureF 1104411 1105415 + urease accessory protein similar to SP:P25261 SP:P24599 PID:43474 gene gene1078 http://www.ncbi.nlm.nih.gov/gene/?term=HI1040 HI1041 HI1041 HI1041 1105412 1106326 + modification methylase similar to SP:P24600 SP:P25267 PID:43482 gene gene1079 http://www.ncbi.nlm.nih.gov/gene/?term=HI1041 HI1042 HI1042 HI1042 1106472 1108324 - gene gene1080 http://www.ncbi.nlm.nih.gov/gene/?term=HI1042 HI1043 HI1043 napF napF 1108431 1108931 - ferredoxin-type protein similar to SP:P33939 PID:453990 GB:U00096 PID:1736849 PID:1788536 gene gene1081 http://www.ncbi.nlm.nih.gov/gene/?term=HI1043 HI1044 HI1044 HI1044 1108931 1109542 - twin-argninine leader-binding protein DmsD binds to the twin-arginine signal peptides of certain proteins%2C including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane gene gene1082 http://www.ncbi.nlm.nih.gov/gene/?term=HI1044 HI1045 HI1045 dmsC dmsC 1109654 1110493 - anaerobic dimethyl sulfoxide reductase subunit C similar to GB:J03412 SP:P18777 PID:145757 GB:U00096 PID:1651423 gene gene1083 http://www.ncbi.nlm.nih.gov/gene/?term=HI1045 HI1046 HI1046 dmsB dmsB 1110495 1111112 - anaerobic dimethyl sulfoxide reductase subunit B similar to GB:J03412 SP:P18776 PID:145756 GB:U00096 PID:1742612 gene gene1084 http://www.ncbi.nlm.nih.gov/gene/?term=HI1046 HI1047 HI1047 dmsA dmsA 1111123 1113543 - anaerobic dimethyl sulfoxide reductase subunit A similar to GB:J03412 SP:P18775 PID:145755 GB:U00096 PID:1651421 gene gene1085 http://www.ncbi.nlm.nih.gov/gene/?term=HI1047 HI1048 HI1048 HI1048 1113797 1114906 + hypothetical protein gene gene1086 http://www.ncbi.nlm.nih.gov/gene/?term=HI1048 HI1049 HI1049 merT merT 1114948 1115241 + mercuric ion transport protein similar to SP:P04140 GB:Z00027 PID:154899 PID:43716 gene gene1087 http://www.ncbi.nlm.nih.gov/gene/?term=HI1049 HI1050 HI1050 merP merP 1115250 1115528 + mercuric ion scavenger protein similar to PID:1143574 SP:Q54463 gene gene1088 http://www.ncbi.nlm.nih.gov/gene/?term=HI1050 HI1051 HI1051 HI1051 1115653 1117497 - ABC transporter ATP-binding protein similar to GB:AL009126 gene gene1089 http://www.ncbi.nlm.nih.gov/gene/?term=HI1051 HI1052 HI1052 HI1052 1117575 1118471 - AraC family transcriptional regulator similar to SP:P35319 PID:581707 gene gene1090 http://www.ncbi.nlm.nih.gov/gene/?term=HI1052 HI1053 HI1053 HI1053 1118583 1118924 + hypothetical protein similar to GB:M66060 SP:P27749 PID:141897 gene gene1091 http://www.ncbi.nlm.nih.gov/gene/?term=HI1053 HI1054 HI1054 HI1054 1119024 1121811 - gene gene1092 http://www.ncbi.nlm.nih.gov/gene/?term=HI1054 HI1056 HI1056 HI1056 1121801 1123690 - type III restriction-modification system methyltransferase-like protein gene gene1093 http://www.ncbi.nlm.nih.gov/gene/?term=HI1056 HI1058 HI1058 HI1058 1123464 1124048 - hypothetical protein gene gene1094 http://www.ncbi.nlm.nih.gov/gene/?term=HI1058 HI1059 HI1059 rnhB rnhB 1124264 1124857 - ribonuclease HII RNH2%3B RNase HII%3B binds manganese%3B endonuclease which specifically degrades the RNA of RNA-DNA hybrids gene gene1095 http://www.ncbi.nlm.nih.gov/gene/?term=HI1059 HI1060 HI1060 lpxB lpxB 1124850 1126022 - lipid-A-disaccharide synthase catalyzes the formation of lipid A disaccharide from UDP-2%2C3-diacylglucosamine and 2%2C3-diacylglucosamine-1-phosphate%2C lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM gene gene1096 http://www.ncbi.nlm.nih.gov/gene/?term=HI1060 HI1061 HI1061 lpxA lpxA 1126089 1126877 - acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis gene gene1097 http://www.ncbi.nlm.nih.gov/gene/?term=HI1061 HI1062 HI1062 fabZ fabZ 1126891 1127337 - (3R)-hydroxymyristoyl-ACP dehydratase in Pseudomonas aeruginosa this enzyme is a trimer of dimers%3B essential for membrane formation%3B performs third step of type II fatty acid biosynthesis%3B catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP gene gene1098 http://www.ncbi.nlm.nih.gov/gene/?term=HI1062 HI1063 HI1063 HI1063 1127423 1129038 - gene gene1099 http://www.ncbi.nlm.nih.gov/gene/?term=HI1063 HI1065 HI1065 pyrH pyrH 1129110 1129823 + uridylate kinase Catalyzes the phosphorylation of UMP to UDP gene gene1100 http://www.ncbi.nlm.nih.gov/gene/?term=HI1065 HI1066 HI1066 nrfD nrfD 1130062 1131027 - nitrite reductase transmembrane protein similar to SP:P32709 GB:X72298 PID:396408 PID:404305 GB:U00096 gene gene1101 http://www.ncbi.nlm.nih.gov/gene/?term=HI1066 HI1067 HI1067 nrfC nrfC 1131024 1131701 - nitrite reductase Fe-S protein similar to SP:P32708 GB:X72298 PID:396407 PID:404304 GB:U00096 gene gene1102 http://www.ncbi.nlm.nih.gov/gene/?term=HI1067 HI1068 HI1068 nrfB nrfB 1131698 1132345 - cytochrome c nitrite reductase pentaheme subunit part of nitrite reductase complex%3B NrfB is active at high nitrate conditions%3B NrfA%2C B%2C C%2C and D are essential for the formate-dependent nitrite reduction to ammonia gene gene1103 http://www.ncbi.nlm.nih.gov/gene/?term=HI1068 HI1069 HI1069 nrfA nrfA 1132422 1134038 - cytochrome c552 catalyzes the formate-dependent reduction of nitrite to ammonia%3B cytochrome C552 gene gene1104 http://www.ncbi.nlm.nih.gov/gene/?term=HI1069 HI1070 HI1070 hrpa hrpa 1134200 1138042 - ATP-dependent RNA helicase HrpA involved in the post-transcriptional processing of the daa operon mRNA%2C which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain gene gene1105 http://www.ncbi.nlm.nih.gov/gene/?term=HI1070 HI1073 HI1073 HI1073 1138111 1138485 - hypothetical protein similar to SP:P32065 GB:U01030 GB:X73413 PID:312767 PID:523332 gene gene1106 http://www.ncbi.nlm.nih.gov/gene/?term=HI1073 HI1074 HI1074 HI1074 1138486 1138938 - hypothetical protein similar to GB:U00096 PID:1788090 gene gene1107 http://www.ncbi.nlm.nih.gov/gene/?term=HI1074 HI1075 HI1075 cydB cydB 1139203 1140339 - cytochrome oxidase subunit II similar to GB:J03939 SP:P11027 PID:145640 GB:U00096 PID:1651328 gene gene1108 http://www.ncbi.nlm.nih.gov/gene/?term=HI1075 HI1076 HI1076 cydA cydA 1140354 1141919 - cytochrome D ubiquinol oxidase subunit I similar to GB:J03939 SP:P11026 PID:497637 GB:U00096 PID:1651327 gene gene1109 http://www.ncbi.nlm.nih.gov/gene/?term=HI1076 HI1077 HI1077 pyrG pyrG 1142571 1144208 + CTP synthetase CTP synthase%3B cytidine triphosphate synthetase%3B catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen%3B in Escherichia coli this enzyme forms a homotetramer gene gene1110 http://www.ncbi.nlm.nih.gov/gene/?term=HI1077 HI1077a HI1077a pnuC pnuC 1144501 1145035 - gene gene1111 http://www.ncbi.nlm.nih.gov/gene/?term=HI1077a HI1078 HI1078 HI1078 1145211 1145978 - amino acid ABC transporter ATP-binding protein similar to SP:P39456 gene gene1112 http://www.ncbi.nlm.nih.gov/gene/?term=HI1078 HI1079m HI1079m HI1079m 1145988 1146704 - amino acid ABC transporter permease gene gene1113 http://www.ncbi.nlm.nih.gov/gene/?term=HI1079m HI1080 HI1080 HI1080 1146688 1147461 - amino acid ABC transporter substrate-binding protein similar to SP:P42199 gene gene1114 http://www.ncbi.nlm.nih.gov/gene/?term=HI1080 HI1081 HI1081 murZ murZ 1147762 1149036 - UDP-N-acetylglucosamine 1-carboxyvinyltransferase adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation%3B gram-positive bacteria have 2 copies of MurA which are active gene gene1115 http://www.ncbi.nlm.nih.gov/gene/?term=HI1081 HI1082 HI1082 HI1082 1149047 1149304 - hypothetical protein similar to SP:P43781 PID:606128 GB:U00096 PID:1789581 gene gene1116 http://www.ncbi.nlm.nih.gov/gene/?term=HI1082 HI1083 HI1083 HI1083 1149325 1149642 - NTP binding protein similar to GB:M34995 SP:P17903 GB:L35574 PID:143458 PID:1881281 gene gene1117 http://www.ncbi.nlm.nih.gov/gene/?term=HI1083 HI1084 HI1084 HI1084 1149653 1150297 - ABC transporter similar to SP:P45390 PID:606130 GB:U00096 PID:1789583 gene gene1118 http://www.ncbi.nlm.nih.gov/gene/?term=HI1084 HI1085 HI1085 HI1085 1150327 1150830 - ABC transporter substrate-binding protein similar to SP:P45391 PID:606131 GB:U00096 PID:1789584 gene gene1119 http://www.ncbi.nlm.nih.gov/gene/?term=HI1085 HI1086 HI1086 HI1086 1150841 1151626 - ABC transporter permease similar to SP:P45392 PID:606132 GB:U00096 PID:1789585 gene gene1120 http://www.ncbi.nlm.nih.gov/gene/?term=HI1086 HI1087 HI1087 HI1087 1151623 1152417 - ABC transporter ATP-binding protein similar to SP:P45393 PID:606133 GB:U00096 PID:1789586 gene gene1121 http://www.ncbi.nlm.nih.gov/gene/?term=HI1087 HI1088 HI1088 sodA sodA 1152847 1153494 - superoxide dismutase similar to GB:X73832 PID:1574643 gene gene1122 http://www.ncbi.nlm.nih.gov/gene/?term=HI1088 HI1089 HI1089 ccmA ccmA 1153743 1154381 + cytochrome c biogenesis protein CcmA ATP-binding protein%3B required for proper cytochrome c maturation gene gene1123 http://www.ncbi.nlm.nih.gov/gene/?term=HI1089 HI1090 HI1090 ccmB ccmB 1154386 1155051 + heme exporter protein B similar to SP:P33930 PID:405925 GB:U00096 PID:1788528 gene gene1124 http://www.ncbi.nlm.nih.gov/gene/?term=HI1090 HI1091 HI1091 ccmC ccmC 1155109 1155849 + heme exporter protein C similar to SP:P33929 PID:405924 GB:U00096 PID:1788527 gene gene1125 http://www.ncbi.nlm.nih.gov/gene/?term=HI1091 HI1092 HI1092 ccmD ccmD 1155891 1156094 + heme exporter protein D similar to SP:P36770 PID:453988 GB:U00096 PID:1788526 gene gene1126 http://www.ncbi.nlm.nih.gov/gene/?term=HI1092 HI1093 HI1093 ccmE ccmE 1156091 1156612 + cytochrome c-type biogenesis protein CcmE CycJ%3B periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes%3B requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome%3B part of the cytochrome c maturation system%3B periplasmic protein anchored to the inner membrane gene gene1127 http://www.ncbi.nlm.nih.gov/gene/?term=HI1093 HI1094 HI1094 ccmF ccmF 1156609 1158555 + cytochrome C-type biogenesis protein similar to SP:P33927 PID:405921 GB:U00096 PID:1788524 gene gene1128 http://www.ncbi.nlm.nih.gov/gene/?term=HI1094 HI1095 HI1095 dsbE dsbE 1158694 1159239 + thiol-disulfide interchange protein similar to SP:P33926 PID:405920 GB:U00096 PID:1788523 gene gene1129 http://www.ncbi.nlm.nih.gov/gene/?term=HI1095 HI1096m HI1096m ccmH ccmH 1159239 1159700 + cytochrome C-type biogenesis protein gene gene1130 http://www.ncbi.nlm.nih.gov/gene/?term=HI1096m HI1097m HI1097m HI1097m 1159701 1160618 + hypothetical protein gene gene1131 http://www.ncbi.nlm.nih.gov/gene/?term=HI1097m HI1099 HI1099 HI1099 1161239 1161547 + hypothetical protein gene gene1133 http://www.ncbi.nlm.nih.gov/gene/?term=HI1099 HI1099a HI1099a HI1099a 1160739 1161097 + gene gene1132 http://www.ncbi.nlm.nih.gov/gene/?term=HI1099a HI1100 HI1100 ligA ligA 1161552 1163564 - NAD-dependent DNA ligase LigA this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction%3B essential for DNA replication and repair of damaged DNA%3B similar to ligase LigB gene gene1134 http://www.ncbi.nlm.nih.gov/gene/?term=HI1100 HI1101 HI1101 HI1101 1163676 1164662 - cell division protein ZipA interacts with cell division protein FitsZ and may be required to anchor septal ring structure gene gene1135 http://www.ncbi.nlm.nih.gov/gene/?term=HI1101 HI1102 HI1102 cysZ cysZ 1164815 1165633 + sulfate transport protein CysZ role in sulfur assimilation gene gene1136 http://www.ncbi.nlm.nih.gov/gene/?term=HI1102 HI1103 HI1103 cysK cysK 1165732 1166682 + cysteine synthetase similar to GB:M21451 SP:P11096 GB:X12615 PID:145686 PID:41201 gene gene1137 http://www.ncbi.nlm.nih.gov/gene/?term=HI1103 HI1104 HI1104 HI1104 1167406 1168629 + transporter protein similar to PID:1842056 gene gene1138 http://www.ncbi.nlm.nih.gov/gene/?term=HI1104 HI1105 HI1105 rfaF rfaF 1168738 1169778 - ADP-heptose-LPS heptosyltransferase II similar to SP:P37692 PID:466758 GB:U00096 PID:1790050 gene gene1139 http://www.ncbi.nlm.nih.gov/gene/?term=HI1105 HI1106 HI1106 xylR xylR 1169854 1171017 - xylose operon regulatory protein similar to SP:P37390 PID:466707 GB:U00096 PID:1789993 gene gene1140 http://www.ncbi.nlm.nih.gov/gene/?term=HI1106 HI1107 HI1107 nhaC nhaC 1171129 1172535 - Na+/H+ antiporter similar to GB:U61539 SP:P27611 PID:143245 PID:2209268 gene gene1141 http://www.ncbi.nlm.nih.gov/gene/?term=HI1107 HI1108 HI1108 patB patB 1172537 1173709 - gene gene1142 http://www.ncbi.nlm.nih.gov/gene/?term=HI1108 HI1109 HI1109 xylH xylH 1173984 1175111 - D-xylose ABC transporter permease similar to SP:P37389 PID:466706 GB:U00096 PID:1789992 gene gene1143 http://www.ncbi.nlm.nih.gov/gene/?term=HI1109 HI1110 HI1110 xylG xylG 1175115 1176626 - xylose transporter ATP-binding protein with XylFH is part of the high affinity xylose ABC transporter gene gene1144 http://www.ncbi.nlm.nih.gov/gene/?term=HI1110 HI1111 HI1111 xylF xylF 1176677 1177675 - D-xylose transporter subunit XylF periplasmic substrate-binding component of the ATP-dependent xylose transport system%3B high affinity gene gene1145 http://www.ncbi.nlm.nih.gov/gene/?term=HI1111 HI1112 HI1112 xylA xylA 1177909 1179228 + xylose isomerase catalyzes the interconversion of D-xylose to D-xylulose gene gene1146 http://www.ncbi.nlm.nih.gov/gene/?term=HI1112 HI1113 HI1113 HI1113 1179231 1180766 + xylulose kinase similar to PID:2293419 gene gene1147 http://www.ncbi.nlm.nih.gov/gene/?term=HI1113 HI1114 HI1114 rfaD rfaD 1180817 1181743 - ADP-L-glycero-D-mannoheptose-6-epimerase catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose gene gene1148 http://www.ncbi.nlm.nih.gov/gene/?term=HI1114 HI1115 HI1115 HI1115 1181796 1182299 - thioredoxin similar to PID:1213065 SP:P52229 gene gene1149 http://www.ncbi.nlm.nih.gov/gene/?term=HI1115 HI1116 HI1116 deoC deoC 1182410 1183081 + 2-deoxyribose-5-phosphate aldolase catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate gene gene1150 http://www.ncbi.nlm.nih.gov/gene/?term=HI1116 HI1117 HI1117 comM comM 1183115 1184644 - competence protein similar to GB:M37337 SP:P22787 PID:147774 PID:147775 PID:148173 gene gene1151 http://www.ncbi.nlm.nih.gov/gene/?term=HI1117 HI1118 HI1118 engB engB 1184759 1185376 - ribosome biogenesis GTP-binding protein YsxC binds guanine nucleotides%3B in Escherichia coli depletion results in defective cell division and filamentation%3B in Bacillus subtilis this gene is essential gene gene1152 http://www.ncbi.nlm.nih.gov/gene/?term=HI1118 HI1119 HI1119 lapB lapB 1185469 1186347 + membrane protein similar to SP:P32181 GB:M59210 PID:387858 gene gene1153 http://www.ncbi.nlm.nih.gov/gene/?term=HI1119 HI1120 HI1120 oppF oppF 1186387 1187385 - oligopeptide ABC transporter ATP-binding protein similar to GB:U00096 SP:P77737 PID:1742036 PID:1787500 PID:1805528 gene gene1154 http://www.ncbi.nlm.nih.gov/gene/?term=HI1120 HI1121 HI1121 oppD oppD 1187382 1188353 - oligopeptide transporter ATP-binding protein similar to SP:P04285 GB:X05491 GB:X52093 PID:47805 gene gene1155 http://www.ncbi.nlm.nih.gov/gene/?term=HI1121 HI1122 HI1122 oppC oppC 1188363 1189298 - oligopeptide ABC transporter permease similar to SP:P08006 GB:X05491 GB:X52093 PID:47804 gene gene1156 http://www.ncbi.nlm.nih.gov/gene/?term=HI1122 HI1123 HI1123 oppB oppB 1189308 1190228 - oligopeptide transporter permease similar to GB:U00096 PID:1742033 PID:1787497 PID:1805525 gene gene1157 http://www.ncbi.nlm.nih.gov/gene/?term=HI1123 HI1124 HI1124 oppA oppA 1190309 1191934 - oligopeptide ABC transporter substrate-binding protein similar to SP:P06202 GB:X05491 GB:X52093 PID:47802 PID:47808 gene gene1158 http://www.ncbi.nlm.nih.gov/gene/?term=HI1124 HI1125 HI1125 talB talB 1192230 1193183 + transaldolase B Maintains the balance of metabolites in the pentose-phosphate pathway gene gene1159 http://www.ncbi.nlm.nih.gov/gene/?term=HI1125 HI1126.1 HI1126.1 HI1126.1 1194246 1195848 + gene gene1160 http://www.ncbi.nlm.nih.gov/gene/?term=HI1126.1 HI1129 HI1129 HI1129 1196050 1196505 + cell division protein MraZ MraZ%3B UPF0040%3B crystal structure shows similarity to AbrB gene gene1161 http://www.ncbi.nlm.nih.gov/gene/?term=HI1129 HI1130 HI1130 mraW mraW 1196536 1197501 + S-adenosyl-methyltransferase MraW similar to GB:D10483 SP:P18595 GB:X52063 PID:216497 PID:40850 gene gene1162 http://www.ncbi.nlm.nih.gov/gene/?term=HI1130 HI1131 HI1131 ftsL ftsL 1197504 1197827 + cell division protein similar to SP:P22187 GB:K00137 GB:S49802 GB:S49875 GB:X52063 gene gene1163 http://www.ncbi.nlm.nih.gov/gene/?term=HI1131 HI1132 HI1132 ftsI ftsI 1197840 1199672 + penicillin-binding protein 3 similar to GB:D10483 SP:P04286 GB:K00137 GB:S49802 GB:S49875 gene gene1164 http://www.ncbi.nlm.nih.gov/gene/?term=HI1132 HI1133 HI1133 murE murE 1199682 1201148 + UDP-N-acetylmuramoylalanyl-D-glutamate--2%2C6-diaminopimelate ligase involved in cell wall formation%3B peptidoglycan synthesis%3B cytoplasmic enzyme%3B catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate gene gene1165 http://www.ncbi.nlm.nih.gov/gene/?term=HI1133 HI1134 HI1134 murF murF 1201162 1202535 + UDP-MurNAc-pentapeptide synthetase similar to GB:D10483 SP:P11880 PID:216500 PID:40854 PID:42048 gene gene1166 http://www.ncbi.nlm.nih.gov/gene/?term=HI1134 HI1135 HI1135 mraY mraY 1202529 1203611 + phospho-N-acetylmuramoyl-pentapeptide-transferase First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan gene gene1167 http://www.ncbi.nlm.nih.gov/gene/?term=HI1135 HI1136 HI1136 murD murD 1203734 1205047 + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase UDP-N-acetylmuramoylalanine--D-glutamate ligase%3B involved in peptidoglycan biosynthesis%3B cytoplasmic%3B catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation gene gene1168 http://www.ncbi.nlm.nih.gov/gene/?term=HI1136 HI1137 HI1137 ftsW ftsW 1205069 1206253 + cell division protein similar to GB:D10483 SP:P16457 GB:M30807 PID:146039 PID:216503 gene gene1169 http://www.ncbi.nlm.nih.gov/gene/?term=HI1137 HI1138 HI1138 murG murG 1206265 1207320 + undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase%3B involved in cell wall formation%3B inner membrane-associated%3B last step of peptidoglycan synthesis gene gene1170 http://www.ncbi.nlm.nih.gov/gene/?term=HI1138 HI1139 HI1139 murC murC 1207458 1208885 + UDP-N-acetylmuramate--L-alanine ligase Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis gene gene1171 http://www.ncbi.nlm.nih.gov/gene/?term=HI1139 HI1140 HI1140 ddl ddl 1208957 1209877 + D-alanine--D-alanine ligase D-alanine--D-alanine ligase%3B DdlA%3B DdlB%3B cytoplasmic%3B catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis%3B there are two forms of this enzyme in Escherichia coli gene gene1172 http://www.ncbi.nlm.nih.gov/gene/?term=HI1140 HI1141 HI1141 ftsQ ftsQ 1209877 1210641 + cell division protein similar to GB:D10483 SP:P06136 GB:K02668 GB:X02821 PID:145725 gene gene1173 http://www.ncbi.nlm.nih.gov/gene/?term=HI1141 HI1142 HI1142 ftsA ftsA 1210660 1211937 + cell division protein similar to GB:D10483 SP:P06137 GB:K02668 GB:M36531 GB:X02821 gene gene1174 http://www.ncbi.nlm.nih.gov/gene/?term=HI1142 HI1143 HI1143 ftsZ ftsZ 1212021 1213286 + cell division protein FtsZ GTPase%3B similar structure to tubulin%3B forms ring-shaped polymers at the site of cell division%3B other proteins such as FtsA%2C ZipA%2C and ZapA%2C interact with and regulate FtsZ function gene gene1175 http://www.ncbi.nlm.nih.gov/gene/?term=HI1143 HI1144 HI1144 lpxC lpxC 1213325 1214242 + UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase zinc-dependent%3B catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis gene gene1176 http://www.ncbi.nlm.nih.gov/gene/?term=HI1144 HI1145 HI1145 pheA pheA 1214369 1215526 + chorismate mutase/prephenate dehydratase similar to SP:Q02286 GB:M74134 GB:X60420 PID:148468 PID:43344 gene gene1177 http://www.ncbi.nlm.nih.gov/gene/?term=HI1145 HI1146 HI1146 HI1146 1215571 1216428 - hypothetical protein similar to SP:P33995 GB:Z27094 PID:414888 PID:551341 PID:606144 gene gene1178 http://www.ncbi.nlm.nih.gov/gene/?term=HI1146 HI1147 HI1147 ptsN ptsN 1216446 1216940 - nitrogen regulatory IIA protein similar to GB:D12938 SP:P31222 GB:Z27094 PID:285783 PID:414887 gene gene1179 http://www.ncbi.nlm.nih.gov/gene/?term=HI1147 HI1148 HI1148 HI1148 1216943 1217668 - ABC transporter ATP-binding protein similar to GB:D12938 SP:P31220 PID:285780 PID:551337 PID:606140 gene gene1180 http://www.ncbi.nlm.nih.gov/gene/?term=HI1148 HI1149m HI1149m HI1149m 1217672 1218190 - hypothetical protein gene gene1181 http://www.ncbi.nlm.nih.gov/gene/?term=HI1149m HI1150 HI1150 HI1150 1218171 1218785 - hypothetical protein similar to SP:P45397 PID:606138 GB:U00096 PID:1789591 gene gene1182 http://www.ncbi.nlm.nih.gov/gene/?term=HI1150 HI1151 HI1151 HI1151 1218836 1219372 - hypothetical protein similar to SP:P26650 GB:M95096 PID:148266 PID:537076 GB:U00096 gene gene1183 http://www.ncbi.nlm.nih.gov/gene/?term=HI1151 HI1152 HI1152 pmbA pmbA 1219461 1220816 + hypothetical protein similar to SP:P24231 GB:X54152 PID:42440 PID:537077 GB:U00096 gene gene1184 http://www.ncbi.nlm.nih.gov/gene/?term=HI1152 HI1153 HI1153 hpt hpt 1221027 1221566 + hypoxanthine-guanine phosphoribosyltransferase Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine%2C respectively gene gene1185 http://www.ncbi.nlm.nih.gov/gene/?term=HI1153 HI1154 HI1154 HI1154 1221872 1223194 + proton glutamate symport protein similar to GB:U00096 PID:1742823 PID:1742828 PID:1788024 gene gene1186 http://www.ncbi.nlm.nih.gov/gene/?term=HI1154 HI1154.1 HI1154.1 HI1154.1 1223883 1223996 + gene gene1188 http://www.ncbi.nlm.nih.gov/gene/?term=HI1154.1 HI1155 HI1155 nrdG nrdG 1223294 1223761 - anaerobic ribonucleotide reductase-activating protein activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions gene gene1187 http://www.ncbi.nlm.nih.gov/gene/?term=HI1155 HI1156 HI1156 cydC cydC 1224009 1225739 - cysteine/glutathione ABC transporter membrane protein/ATP-binding protein in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance%3B important for cytochrome bd and c gene gene1189 http://www.ncbi.nlm.nih.gov/gene/?term=HI1156 HI1157 HI1157 cydD cydD 1225739 1227499 - cysteine/glutathione ABC transporter membrane protein/ATP-binding protein in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance%3B important for cytochrome bd and c gene gene1190 http://www.ncbi.nlm.nih.gov/gene/?term=HI1157 HI1158 HI1158 trxB trxB 1227571 1228527 - thioredoxin reductase similar to GB:J03762 SP:P09625 PID:148073 PID:347239 GB:U00096 gene gene1191 http://www.ncbi.nlm.nih.gov/gene/?term=HI1158 HI1159m HI1159m HI1159m 1228601 1229459 - thioredoxin domain-containing protein contains frameshifts gene gene1192 http://www.ncbi.nlm.nih.gov/gene/?term=HI1159m HI1160 HI1160 hemH hemH 1229539 1230510 - ferrochelatase protoheme ferro-lyase%3B catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme%3B involved in protoheme biosynthesis%3B in some organisms this protein is membrane-associated while in others it is cytosolic gene gene1193 http://www.ncbi.nlm.nih.gov/gene/?term=HI1160 HI1161 HI1161 HI1161 1230507 1230923 - hypothetical protein similar to GB:M24143 SP:P15050 PID:450383 PID:522184 GB:U00096 gene gene1194 http://www.ncbi.nlm.nih.gov/gene/?term=HI1161 HI1162 HI1162 HI1162 1231372 1231845 - hypothetical protein similar to SP:P45736 GB:U00096 PID:1279405 PID:1787546 gene gene1195 http://www.ncbi.nlm.nih.gov/gene/?term=HI1162 HI1163 HI1163 HI1163 1231849 1234932 - hypothetical protein similar to GB:U00096 SP:P77748 PID:1742760 PID:1787977 gene gene1196 http://www.ncbi.nlm.nih.gov/gene/?term=HI1163 HI1164 HI1164 ompA ompA 1235301 1236362 + outer membrane protein P5 similar to GB:L20309 SP:P38368 gene gene1197 http://www.ncbi.nlm.nih.gov/gene/?term=HI1164 HI1165 HI1165 HI1165 1236513 1236836 + hypothetical protein similar to PID:2407233 gene gene1198 http://www.ncbi.nlm.nih.gov/gene/?term=HI1165 HI1166 HI1166 hisH hisH 1236913 1238013 - histidinol-phosphate aminotransferase catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis gene gene1199 http://www.ncbi.nlm.nih.gov/gene/?term=HI1166 HI1167 HI1167 serC serC 1238101 1239189 - 3-phosphoserine/phosphohydroxythreonine aminotransferase catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate%3B required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine gene gene1200 http://www.ncbi.nlm.nih.gov/gene/?term=HI1167 HI1168 HI1168 HI1168 1239380 1239724 + hypothetical protein similar to GB:U00096 PID:1788317 gene gene1201 http://www.ncbi.nlm.nih.gov/gene/?term=HI1168 HI1168a HI1168a HI1168a 1239765 1240331 - hypothetical protein gene gene1202 http://www.ncbi.nlm.nih.gov/gene/?term=HI1168a HI1169 HI1169 HI1169 1240331 1241317 - para-aminobenzoate synthase component I gene gene1203 http://www.ncbi.nlm.nih.gov/gene/?term=HI1169 HI1171 HI1171 trpG trpG 1241359 1241940 + anthranilate synthase component II catalyzes the formation of anthranilate from chorismate and glutamine%3B functions in tryptophan biosynthesis gene gene1204 http://www.ncbi.nlm.nih.gov/gene/?term=HI1171 HI1172 HI1172 metX metX 1242025 1243179 + S-adenosylmethionine synthetase catalyzes the formation of S-adenosylmethionine from methionine and ATP%3B methionine adenosyltransferase gene gene1205 http://www.ncbi.nlm.nih.gov/gene/?term=HI1172 HI1173 HI1173 sprT sprT 1243518 1243988 + hypothetical protein similar to SP:P39902 PID:1208420 PID:882473 GB:U00096 PID:1789313 gene gene1206 http://www.ncbi.nlm.nih.gov/gene/?term=HI1173 HI1174 HI1174 HI1174 1244067 1244552 + opacity protein similar to GB:X15780 PID:1333789 gene gene1207 http://www.ncbi.nlm.nih.gov/gene/?term=HI1174 HI1177 HI1177 artM artM 1245169 1245852 - arginine ABC transporter permease ArtM with ArtPQJI acts to transport arginine across the inner membrane gene gene1208 http://www.ncbi.nlm.nih.gov/gene/?term=HI1177 HI1178 HI1178 artQ artQ 1245852 1246517 - arginine ABC transporter permease ArtQ with ArtPMJI transports arginine across the inner membrane gene gene1209 http://www.ncbi.nlm.nih.gov/gene/?term=HI1178 HI1179 HI1179 artI artI 1246521 1247240 - arginine ABC transporter substrate-binding protein similar to GB:M59210 SP:P49618 PID:387859 gene gene1210 http://www.ncbi.nlm.nih.gov/gene/?term=HI1179 HI1180 HI1180 artP artP 1247258 1247989 - arginine ABC transporter ATP-binding protein With ArtMQJI transports arginine across the inner membrane gene gene1211 http://www.ncbi.nlm.nih.gov/gene/?term=HI1180 HI1181 HI1181 gmhA gmhA 1248116 1248700 - phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate gene gene1212 http://www.ncbi.nlm.nih.gov/gene/?term=HI1181 HI1183 HI1183 HI1183 1248907 1249712 + gene gene1213 http://www.ncbi.nlm.nih.gov/gene/?term=HI1183 HI1184 HI1184 dppF dppF 1249741 1250724 - dipeptide transporter ATP-binding protein Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides gene gene1214 http://www.ncbi.nlm.nih.gov/gene/?term=HI1184 HI1185 HI1185 dppD dppD 1250727 1251719 - dipeptide transporter ATP-binding protein DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF gene gene1215 http://www.ncbi.nlm.nih.gov/gene/?term=HI1185 HI1186 HI1186 dppC dppC 1251729 1252616 - dipeptide ABC transporter permease similar to SP:P37315 PID:349227 PID:466681 GB:U00096 PID:1789964 gene gene1216 http://www.ncbi.nlm.nih.gov/gene/?term=HI1186 HI1187 HI1187 dppB dppB 1252631 1253602 - dipeptide ABC transporter permease similar to SP:P37316 PID:349226 PID:466682 GB:U00096 PID:1789965 gene gene1217 http://www.ncbi.nlm.nih.gov/gene/?term=HI1187 HI1188 HI1188 uvrD uvrD 1253722 1255905 - DNA-dependent helicase II unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present%3B involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair. gene gene1218 http://www.ncbi.nlm.nih.gov/gene/?term=HI1188 HI1189 HI1189 HI1189 1256516 1257151 - 7-carboxy-7-deazaguanine synthase similar to PID:1652793 gene gene1219 http://www.ncbi.nlm.nih.gov/gene/?term=HI1189 HI1190 HI1190 HI1190 1257152 1257577 - 6-pyruvoyl tetrahydrobiopterin synthase similar to PID:882658 GB:U00096 SP:Q46903 PID:1789124 gene gene1220 http://www.ncbi.nlm.nih.gov/gene/?term=HI1190 HI1191 HI1191 HI1191 1257570 1258257 - gene gene1221 http://www.ncbi.nlm.nih.gov/gene/?term=HI1191 HI1192 HI1192 HI1192 1258413 1258556 + hypothetical protein gene gene1222 http://www.ncbi.nlm.nih.gov/gene/?term=HI1192 HI1193 HI1193 ilvE ilvE 1258603 1259634 - branched-chain amino acid aminotransferase catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids gene gene1223 http://www.ncbi.nlm.nih.gov/gene/?term=HI1193 HI1194m HI1194m gcvA gcvA 1260108 1261001 + DNA-binding transcriptional activator GcvA Glycine cleavage system transcriptional activator%3B activates the gcvTHP operon in the presence of glycine and represses the operon in its absence gene gene1224 http://www.ncbi.nlm.nih.gov/gene/?term=HI1194m HI1195m HI1195m HI1195m 1260994 1262085 + 23S rRNA (cytidine(2498)-2'-O)-methyltransferase RlmM gene gene1225 http://www.ncbi.nlm.nih.gov/gene/?term=HI1195m HI1196 HI1196 sucC sucC 1262121 1263290 + succinyl-CoA synthetase subunit beta catalyzes the interconversion of succinyl-CoA and succinate gene gene1226 http://www.ncbi.nlm.nih.gov/gene/?term=HI1196 HI1197 HI1197 sucD sucD 1263290 1264171 + succinyl-CoA synthetase subunit alpha similar to GB:J01619 SP:P07459 PID:146204 PID:809679 GB:U00096 gene gene1227 http://www.ncbi.nlm.nih.gov/gene/?term=HI1197 HI1198 HI1198 HI1198 1264292 1264915 + hypothetical protein similar to SP:P45847 PID:602960 GB:U00096 PID:1787521 gene gene1228 http://www.ncbi.nlm.nih.gov/gene/?term=HI1198 HI1199 HI1199 HI1199 1264963 1266036 + 23S rRNA pseudouridylate synthase B similar to PID:602963 GB:U00096 PID:1787524 gene gene1229 http://www.ncbi.nlm.nih.gov/gene/?term=HI1199 HI1200 HI1200 cysB cysB 1266047 1267018 + transcriptional regulator CysB LysR-type transcriptional regulator%3B contains helix-turn-helix (HTH) motif%3B in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon%3B autoregulates expression%3B crystal structure of Klebsiella aerogenes showed tetramer formation gene gene1230 http://www.ncbi.nlm.nih.gov/gene/?term=HI1200 HI1201 HI1201 HI1201 1267077 1268021 - N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase involved in methylation of ribosomal protein L3 gene gene1231 http://www.ncbi.nlm.nih.gov/gene/?term=HI1201 HI1202 HI1202 HI1202 1268132 1268656 + hypothetical protein similar to GB:U00096 PID:1788671 gene gene1232 http://www.ncbi.nlm.nih.gov/gene/?term=HI1202 HI1203 HI1203 pta pta 1268731 1270866 - phosphate acetyltransferase catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate%3B when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate gene gene1233 http://www.ncbi.nlm.nih.gov/gene/?term=HI1203 HI1204 HI1204 ackA ackA 1270934 1272139 - acetate kinase AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation%3B utilizes magnesium and ATP%3B also involved in conversion of acetate to aceyl-CoA gene gene1234 http://www.ncbi.nlm.nih.gov/gene/?term=HI1204 HI1205 HI1205 HI1205 1272354 1272797 + hypothetical protein similar to GB:U00096 PID:1788632 GB:U00096 PID:1788632 gene gene1235 http://www.ncbi.nlm.nih.gov/gene/?term=HI1205 HI1206 HI1206 cvpA cvpA 1272884 1273375 + colicin V production protein similar to GB:J01666 SP:P08550 PID:146367 PID:147415 GB:U00096 gene gene1236 http://www.ncbi.nlm.nih.gov/gene/?term=HI1206 HI1207 HI1207 purF purF 1273386 1274903 + amidophosphoribosyltransferase Catalyzes first step of the de novo purine nucleotide biosynthetic pathway gene gene1237 http://www.ncbi.nlm.nih.gov/gene/?term=HI1207 HI1208 HI1208 HI1208 1274958 1275848 - hypothetical protein similar to GB:L42023 PID:1007092 PID:1221333 PID:1205451 PID:1574138 gene gene1238 http://www.ncbi.nlm.nih.gov/gene/?term=HI1208 HI1209 HI1209 argR argR 1275848 1276303 - arginine repressor regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes gene gene1239 http://www.ncbi.nlm.nih.gov/gene/?term=HI1209 HI1210 HI1210 mdh mdh 1276510 1277445 + malate dehydrogenase oxidizes malate to oxaloacetate gene gene1240 http://www.ncbi.nlm.nih.gov/gene/?term=HI1210 HI1211 HI1211 lysS lysS 1277530 1279038 - lysine--tRNA ligase class II%3B LysRS2%3B catalyzes a two-step reaction%2C first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B in Methanosarcina barkeri%2C LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 gene gene1241 http://www.ncbi.nlm.nih.gov/gene/?term=HI1211 HI1212 HI1212 HI1212 1279189 1279935 - peptide chain release factor 1 gene gene1242 http://www.ncbi.nlm.nih.gov/gene/?term=HI1212 HI1213 HI1213 dsbC dsbC 1280420 1281109 + thiol-disulfide interchange protein similar to GB:M54884 SP:P21892 PID:147549 PID:887843 GB:U00096 gene gene1243 http://www.ncbi.nlm.nih.gov/gene/?term=HI1213 HI1214 HI1214 recJ recJ 1281398 1283125 + single-stranded-DNA-specific exonuclease similar to GB:M54884 SP:P21893 PID:147550 PID:887842 GB:U00096 gene gene1244 http://www.ncbi.nlm.nih.gov/gene/?term=HI1214 HI1215 HI1215 dsbA dsbA 1283130 1283825 + thiol-disulfide interchange protein similar to PID:840949 SP:P50024 gene gene1245 http://www.ncbi.nlm.nih.gov/gene/?term=HI1215 HI1216 HI1216 pfs pfs 1283822 1284511 + 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine gene gene1246 http://www.ncbi.nlm.nih.gov/gene/?term=HI1216 HI1217 HI1217 HI1217 1284588 1287329 - transferrin-binding protein similar to PID:2764817 gene gene1247 http://www.ncbi.nlm.nih.gov/gene/?term=HI1217 HI1218 HI1218 lctP lctP 1287584 1289182 - L-lactate permease similar to GB:AE000782 gene gene1248 http://www.ncbi.nlm.nih.gov/gene/?term=HI1218 HI1219 HI1219 cmk cmk 1289456 1290157 + cytidylate kinase Catalyzes the formation of (d)CDP from ATP and (d)CMP gene gene1249 http://www.ncbi.nlm.nih.gov/gene/?term=HI1219 HI1220 HI1220 rpsA rpsA 1290233 1291882 + 30S ribosomal protein S1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit%3B autoregulates expression via a C-terminal domain%3B in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats%3B the S1 nucleic acid-binding domain is found associated with other proteins gene gene1250 http://www.ncbi.nlm.nih.gov/gene/?term=HI1220 HI1221 HI1221 ihfB ihfB 1292005 1292289 + integration host factor subunit beta This protein is one of the two subunits of integration host factor%2C a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control gene gene1251 http://www.ncbi.nlm.nih.gov/gene/?term=HI1221 HI1222 HI1222 HI1222 1292364 1292657 + hypothetical protein similar to GB:U00096 PID:1787535 gene gene1252 http://www.ncbi.nlm.nih.gov/gene/?term=HI1222 HI1223 HI1223 HI1223 1292657 1293847 + hypothetical protein similar to SP:P45576 GB:U00096 PID:2367116 gene gene1253 http://www.ncbi.nlm.nih.gov/gene/?term=HI1223 HI1224 HI1224 pyrF pyrF 1293871 1294563 + orotidine 5'-phosphate decarboxylase type 1 subfamily%3B involved in last step of pyrimidine biosynthesis%3B converts orotidine 5'-phosphate to UMP and carbon dioxide%3B OMP decarboxylase%3B OMPDCase%3B OMPdecase gene gene1254 http://www.ncbi.nlm.nih.gov/gene/?term=HI1224 HI1225 HI1225 HI1225 1294570 1294890 + translation initiation factor Sui1 involved in start site selection during the initiation of translation gene gene1255 http://www.ncbi.nlm.nih.gov/gene/?term=HI1225 HI1225.1 HI1225.1 HI1225.1 1294919 1295614 - DNA replication initiation factor controls initiation of DNA replication by inhibiting re-initiation of replication%2C promotes hydrolysis of DnaA-bound ATP gene gene1256 http://www.ncbi.nlm.nih.gov/gene/?term=HI1225.1 HI1227 HI1227 uraA uraA 1295680 1296924 - uracil permease similar to GB:X76083 SP:P41006 PID:431231 gene gene1257 http://www.ncbi.nlm.nih.gov/gene/?term=HI1227 HI1228 HI1228 upp upp 1297029 1297655 - uracil phosphoribosyltransferase Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate gene gene1258 http://www.ncbi.nlm.nih.gov/gene/?term=HI1228 HI1229 HI1229 dnaX dnaX 1297779 1299845 - DNA polymerase III subunits gamma and tau catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand%3B the tau chain serves as a scaffold to help in the dimerizaton of the alpha%2Cepsilon and theta core complex%3B the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA gene gene1259 http://www.ncbi.nlm.nih.gov/gene/?term=HI1229 HI1230 HI1230 apt apt 1299857 1300399 - adenine phosphoribosyltransferase catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis gene gene1260 http://www.ncbi.nlm.nih.gov/gene/?term=HI1230 HI1231 HI1231 lpdA lpdA 1300547 1301983 - dihydrolipoamide dehydrogenase E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex%3B catalyzes the oxidation of dihydrolipoamide to lipoamide gene gene1261 http://www.ncbi.nlm.nih.gov/gene/?term=HI1231 HI1232 HI1232 aceF aceF 1302097 1303800 - dihydrolipoamide acetyltransferase similar to GB:D26562 SP:P06959 GB:V01498 PID:434011 PID:473784 gene gene1262 http://www.ncbi.nlm.nih.gov/gene/?term=HI1232 HI1233 HI1233 aceE aceE 1303863 1306523 - pyruvate dehydrogenase subunit E1 E1 component%3B part of pyruvate dehydrogenase%3B forms a complex with DlaT and LpdC gene gene1263 http://www.ncbi.nlm.nih.gov/gene/?term=HI1233 HI1234 HI1234 mgsA mgsA 1306823 1307281 + methylglyoxal synthase catalyzes the formation of methylglyoxal from glycerone phosphate gene gene1264 http://www.ncbi.nlm.nih.gov/gene/?term=HI1234 HI1235 HI1235 HI1235 1307437 1308878 - gene gene1265 http://www.ncbi.nlm.nih.gov/gene/?term=HI1235 HI1237 HI1237 dnaK dnaK 1309144 1311051 + molecular chaperone DnaK heat shock protein 70%3B assists in folding of nascent polypeptide chains%3B refolding of misfolded proteins%3B utilizes ATPase activity to help fold%3B co-chaperones are DnaJ and GrpE%3B multiple copies in some bacteria gene gene1266 http://www.ncbi.nlm.nih.gov/gene/?term=HI1237 HI1238 HI1238 dnaJ dnaJ 1311102 1312286 + chaperone protein DnaJ chaperone Hsp40%3B co-chaperone with DnaK%3B Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins%2C also in an autonomous%2C dnaK-independent fashion gene gene1267 http://www.ncbi.nlm.nih.gov/gene/?term=HI1238 HI1239 HI1239 proA proA 1312365 1313618 - gamma-glutamyl phosphate reductase Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway gene gene1268 http://www.ncbi.nlm.nih.gov/gene/?term=HI1239 HI1240 HI1240 HI1240 1313639 1314301 - hypothetical protein similar to GB:L10328 SP:P31432 PID:290496 GB:U00096 PID:1790078 gene gene1269 http://www.ncbi.nlm.nih.gov/gene/?term=HI1240 HI1241 HI1241 HI1241 1314399 1315199 + hypothetical protein gene gene1270 http://www.ncbi.nlm.nih.gov/gene/?term=HI1241 HI1242 HI1242 bcr bcr 1315231 1316427 - bicyclomycin/multidrug efflux system Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance gene gene1271 http://www.ncbi.nlm.nih.gov/gene/?term=HI1242 HI1243 HI1243 rsuA rsuA 1316429 1317127 - 16S rRNA pseudouridine(516) synthase similar to SP:P33918 PID:405907 GB:U00096 PID:1788510 gene gene1272 http://www.ncbi.nlm.nih.gov/gene/?term=HI1243 HI1244 HI1244 HI1244 1317218 1317838 - hypothetical protein gene gene1273 http://www.ncbi.nlm.nih.gov/gene/?term=HI1244 HI1245 HI1245 HI1245 1318036 1320306 + malic enzyme NADP-dependent%3B catalyzes the oxidative decarboxylation of malate to form pyruvate%3B decarboxylates oxaloacetate gene gene1274 http://www.ncbi.nlm.nih.gov/gene/?term=HI1245 HI1246 HI1246 HI1246 1320516 1322459 + hypothetical protein gene gene1275 http://www.ncbi.nlm.nih.gov/gene/?term=HI1246 HI1247 HI1247 uvrB uvrB 1322490 1324529 - excinuclease ABC subunit B The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands%2C where it probes for the presence of a lesion gene gene1276 http://www.ncbi.nlm.nih.gov/gene/?term=HI1247 HI1247.1 HI1247.1 HI1247.1 1324965 1325040 + tRNA-Asn tRNA gene1277 http://www.ncbi.nlm.nih.gov/gene/?term=HI1247.1 HI1248 HI1248 HI1248 1325143 1326111 - hypothetical protein gene gene1278 http://www.ncbi.nlm.nih.gov/gene/?term=HI1248 HI1249 HI1249 HI1249 1326114 1326734 - hypothetical protein gene gene1279 http://www.ncbi.nlm.nih.gov/gene/?term=HI1249 HI1250 HI1250 HI1250 1327059 1327364 + hypothetical protein gene gene1280 http://www.ncbi.nlm.nih.gov/gene/?term=HI1250 HI1251 HI1251 vapA vapA 1327375 1327698 + virulence-associated protein A similar to PID:1002991 PID:563265 SP:Q46560 gene gene1281 http://www.ncbi.nlm.nih.gov/gene/?term=HI1251 HI1252 HI1252 HI1252 1327861 1329531 + ABC transporter ATP-binding protein ChvD%3B in Agrobacterium tumefaciens%2C mutations in both Walker boxes were found to affect virulence gene gene1282 http://www.ncbi.nlm.nih.gov/gene/?term=HI1252 HI1253 HI1253 HI1253 1329551 1329934 + hypothetical protein similar to PID:968932 GB:U00096 PID:1787464 gene gene1283 http://www.ncbi.nlm.nih.gov/gene/?term=HI1253 HI1254 HI1254 HI1254 1329939 1331908 + gene gene1284 http://www.ncbi.nlm.nih.gov/gene/?term=HI1254 HI1258 HI1258 mfd mfd 1332180 1335620 + transcription-repair coupling factor similar to SP:P30958 GB:U00096 PID:1651547 PID:1651549 PID:1787357 gene gene1285 http://www.ncbi.nlm.nih.gov/gene/?term=HI1258 HI1259 HI1259 HI1259 1335673 1337073 - serine protease similar to SP:P39099 PID:558912 PID:606173 PID:984379 GB:U00096 gene gene1286 http://www.ncbi.nlm.nih.gov/gene/?term=HI1259 HI1260 HI1260 accD accD 1337267 1338157 + acetyl-CoA carboxylase carboxyltransferase subunit beta catalyzes the carboxylation of acetyl-CoA to malonyl-CoA%3B forms a tetramer of AccA2D2 subunits gene gene1287 http://www.ncbi.nlm.nih.gov/gene/?term=HI1260 HI1261 HI1261 folC folC 1338150 1339463 + folylpolyglutamate synthase/dihydrofolate synthase similar to GB:M68934 SP:P08192 GB:M32445 PID:146009 PID:146020 gene gene1288 http://www.ncbi.nlm.nih.gov/gene/?term=HI1261 HI1262 HI1262 sanA sanA 1339751 1340431 - hypothetical protein similar to SP:P33017 PID:405877 PID:1161522 GB:U00096 PID:1788466 gene gene1289 http://www.ncbi.nlm.nih.gov/gene/?term=HI1262 HI1263 HI1263 metX metX 1340589 1341665 + homoserine O-acetyltransferase Catalyzes the conversion of acetyl-CoA and L-homoserine to CoA and O-acetyl-L-homoserine gene gene1290 http://www.ncbi.nlm.nih.gov/gene/?term=HI1263 HI1264 HI1264 gyrA gyrA 1341719 1344361 - DNA gyrase subunit A negatively supercoils closed circular double-stranded DNA gene gene1291 http://www.ncbi.nlm.nih.gov/gene/?term=HI1264 HI1265 HI1265 HI1265 1344944 1346707 - hypothetical protein similar to GB:U00096 SP:P75838 PID:1787133 gene gene1292 http://www.ncbi.nlm.nih.gov/gene/?term=HI1265 HI1266 HI1266 HI1266 1346844 1347230 - hypothetical protein gene gene1293 http://www.ncbi.nlm.nih.gov/gene/?term=HI1266 HI1268 HI1268 HI1268 1347200 1347744 + gene gene1294 http://www.ncbi.nlm.nih.gov/gene/?term=HI1268 HI1271 HI1271 HI1271 1347741 1348478 + similar to ABC transporter permease protein%3B this region contains an authentic point mutation causing a premature stop and is not the result of a sequencing artifact%3B similar to SP:P15029 GB:M26397 PID:145927 PID:537129 GB:U00096 gene gene1295 http://www.ncbi.nlm.nih.gov/gene/?term=HI1271 HI1272 HI1272 HI1272 1348468 1349259 + ABC transporter ATP-binding protein similar to GB:AE000511 SP:O05732 PID:2072456 PID:2314024 gene gene1296 http://www.ncbi.nlm.nih.gov/gene/?term=HI1272 HI1273 HI1273 HI1273 1349256 1350062 + hypothetical protein similar to PID:1816658 gene gene1297 http://www.ncbi.nlm.nih.gov/gene/?term=HI1273 HI1274 HI1274 HI1274 1350114 1350830 + hydroxyacylglutathione hydrolase similar to PID:1208973 GB:U00096 SP:Q47677 PID:1552782 PID:1786406 gene gene1298 http://www.ncbi.nlm.nih.gov/gene/?term=HI1274 HI1275 HI1275 tehB tehB 1350886 1351746 - tellurite resistance protein TehB with TehA confers resistance to tellurite gene gene1299 http://www.ncbi.nlm.nih.gov/gene/?term=HI1275 HI1276 HI1276 metG metG 1351859 1353907 - methionine--tRNA ligase methionine--tRNA ligase%3B MetRS%3B adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate%3B some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not%3B four subfamilies exist based on sequence motifs and zinc content gene gene1300 http://www.ncbi.nlm.nih.gov/gene/?term=HI1276 HI1277 HI1277 mrp mrp 1354058 1355170 + ATPase similar to SP:P21590 GB:U00007 GB:X55791 PID:405896 PID:42017 gene gene1301 http://www.ncbi.nlm.nih.gov/gene/?term=HI1277 HI1278 HI1278 HI1278 1355217 1355879 - NAD(P)H-flavin oxidoreductase similar to GB:D17743 SP:P46072 PID:517169 gene gene1302 http://www.ncbi.nlm.nih.gov/gene/?term=HI1278 HI1279 HI1279 neuA neuA 1355984 1356670 + acylneuraminate cytidylyltransferase similar to GB:M95053 GB:X78068 GB:U04328 PID:460146 PID:520734 gene gene1303 http://www.ncbi.nlm.nih.gov/gene/?term=HI1279 HI1281 HI1281 HI1281 1356988 1357482 + gene gene1304 http://www.ncbi.nlm.nih.gov/gene/?term=HI1281 HI1281.1 HI1281.1 HI1281.1 1358358 1358434 + tRNA-Met tRNA gene1306 http://www.ncbi.nlm.nih.gov/gene/?term=HI1281.1 HI1281.2 HI1281.2 HI1281.2 1357566 1357931 - tmRNA gene1305 http://www.ncbi.nlm.nih.gov/gene/?term=HI1281.2 HI1282 HI1282 HI1282 1358656 1359111 + hypothetical protein in Streptococcus pneumoniae this gene was found to be essential%3B structure determination of the Streptococcus protein shows that it is similar to a number of other proteins gene gene1307 http://www.ncbi.nlm.nih.gov/gene/?term=HI1282 HI1283 HI1283 nusA nusA 1359128 1360615 + transcription elongation factor NusA modifies transcription through interactions with RNA polymerase affecting elongation%2C readthrough%2C termination%2C and antitermination gene gene1308 http://www.ncbi.nlm.nih.gov/gene/?term=HI1283 HI1284 HI1284 infB infB 1360627 1363116 + translation initiation factor IF-2 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex gene gene1309 http://www.ncbi.nlm.nih.gov/gene/?term=HI1284 HI1285 HI1285 hsdR hsdR 1363195 1366362 - type I restriction enzyme similar to PID:1685100 gene gene1310 http://www.ncbi.nlm.nih.gov/gene/?term=HI1285 HI1286 HI1286 hsdS hsdS 1366454 1367833 - type I restriction/modification specificity protein similar to PID:1685099 gene gene1311 http://www.ncbi.nlm.nih.gov/gene/?term=HI1286 HI1287 HI1287 hsdM hsdM 1367826 1369556 - type I modification enzyme similar to PID:1679866 gene gene1312 http://www.ncbi.nlm.nih.gov/gene/?term=HI1287 HI1288 HI1288 rbfA rbfA 1369672 1370058 + ribosome-binding factor A associates with free 30S ribosomal subunits%3B essential for efficient processing of 16S rRNA%3B in Escherichia coli rbfA is induced by cold shock gene gene1313 http://www.ncbi.nlm.nih.gov/gene/?term=HI1288 HI1289 HI1289 truB truB 1370058 1370996 + tRNA pseudouridine synthase B catalyzes isomerization of specific uridines in RNA to pseudouridine%3B responsible for residues in T loops of many tRNAs gene gene1314 http://www.ncbi.nlm.nih.gov/gene/?term=HI1289 HI1290 HI1290 tyrA tyrA 1371056 1372189 + bifunctional chorismate mutase/prephenate dehydrogenase catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis gene gene1315 http://www.ncbi.nlm.nih.gov/gene/?term=HI1290 HI1291 HI1291 queF queF 1372222 1373061 - 7-cyano-7-deazaguanine reductase catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis gene gene1316 http://www.ncbi.nlm.nih.gov/gene/?term=HI1291 HI1292 HI1292 HI1292 1373188 1373973 - hypothetical protein gene gene1317 http://www.ncbi.nlm.nih.gov/gene/?term=HI1292 HI1293 HI1293 HI1293 1373964 1374344 - hypothetical protein similar to PID:882706 GB:U00096 SP:Q46926 PID:1789176 gene gene1318 http://www.ncbi.nlm.nih.gov/gene/?term=HI1293 HI1295 HI1295 HI1295 1374341 1375534 - selenocysteine lyase similar to PID:882705 GB:U00096 PID:1789175 gene gene1319 http://www.ncbi.nlm.nih.gov/gene/?term=HI1295 HI1296 HI1296 HI1296 1375488 1376003 - nuclease similar to SP:P29769 gene gene1320 http://www.ncbi.nlm.nih.gov/gene/?term=HI1296 HI1297 HI1297 HI1297 1376139 1376561 + hypothetical protein similar to SP:P33372 PID:405872 GB:U00096 PID:1788463 gene gene1321 http://www.ncbi.nlm.nih.gov/gene/?term=HI1297 HI1298 HI1298 HI1298 1376580 1377275 + hypothetical protein similar to SP:P33373 PID:405873 GB:U00096 PID:1788464 gene gene1322 http://www.ncbi.nlm.nih.gov/gene/?term=HI1298 HI1299 HI1299 dgt dgt 1377368 1378752 + gene gene1323 http://www.ncbi.nlm.nih.gov/gene/?term=HI1299 HI1300 HI1300 HI1300 1378846 1380789 + ABC transporter ATP-binding protein Uup%3B in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity%3B mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth gene gene1324 http://www.ncbi.nlm.nih.gov/gene/?term=HI1300 HI1301 HI1301 HI1301 1380817 1381506 - carbonic anhydrase similar to PID:1513236 gene gene1325 http://www.ncbi.nlm.nih.gov/gene/?term=HI1301 HI1302 HI1302 asnC asnC 1381582 1382985 - asparagine--tRNA ligase catalyzes a two-step reaction%2C first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA gene gene1326 http://www.ncbi.nlm.nih.gov/gene/?term=HI1302 HI1303 HI1303 ribH ribH 1383211 1383684 + 6%2C7-dimethyl-8-ribityllumazine synthase RibE%3B 6%2C7-diimethyl-8-ribityllumazine synthase%3B DMRL synthase%3B lumazine synthase%3B beta subunit of riboflavin synthase%3B condenses 5-amino-6-(1'-D)-ribityl-amino-2%2C4(1H%2C3H)-pyrimidinedione with L-3%2C4-dihydrohy-2-butanone-4-phosphate to generate 6%2C6-dimethyl-8-lumazine (DMRL)%3B riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12)%3B involved in the last steps of riboflavin biosynthesis%3B forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli%3B in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not gene gene1327 http://www.ncbi.nlm.nih.gov/gene/?term=HI1303 HI1304 HI1304 nusB nusB 1383688 1384122 + transcription antitermination protein NusB Regulates rRNA biosynthesis by transcriptional antitermination gene gene1328 http://www.ncbi.nlm.nih.gov/gene/?term=HI1304 HI1305 HI1305 thiL thiL 1384139 1385176 + thiamin-monophosphate kinase similar to GB:U00096 SP:P77785 PID:1773101 PID:1786619 PID:2329840 gene gene1329 http://www.ncbi.nlm.nih.gov/gene/?term=HI1305 HI1306 HI1306 pgpA pgpA 1385173 1385664 + phosphatidylglycerophosphatase A similar to GB:U00096 PID:1773102 PID:1786620 PID:2329841 gene gene1330 http://www.ncbi.nlm.nih.gov/gene/?term=HI1306 HI1307 HI1307 HI1307 1385661 1386293 + hypothetical protein similar to GB:U00096 SP:P75693 PID:1657525 PID:1786522 gene gene1331 http://www.ncbi.nlm.nih.gov/gene/?term=HI1307 HI1308 HI1308 dapB dapB 1386310 1387122 + 4-hydroxy-tetrahydrodipicolinate reductase catalyzes the reduction of 2%2C3-dihydrodipicolinate to 2%2C3%2C4%2C5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis gene gene1332 http://www.ncbi.nlm.nih.gov/gene/?term=HI1308 HI1309 HI1309 HI1309 1387117 1387365 - hypothetical protein similar to SP:P37910 GB:U00096 PID:1788568 gene gene1333 http://www.ncbi.nlm.nih.gov/gene/?term=HI1309 HI1310 HI1310 HI1310 1387390 1388151 + hypothetical protein gene gene1334 http://www.ncbi.nlm.nih.gov/gene/?term=HI1310 HI1311 HI1311 pheS pheS 1388300 1389289 + phenylalanine--tRNA ligase subunit alpha catalyzes a two-step reaction%2C first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B forms a heterotetramer of alpha(2)beta(2)%3B binds two magnesium ions per tetramer%3B type 1 subfamily gene gene1335 http://www.ncbi.nlm.nih.gov/gene/?term=HI1311 HI1312 HI1312 pheT pheT 1389323 1391710 + phenylalanine--tRNA ligase subunit beta catalyzes a two-step reaction%2C first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B forms a tetramer of alpha(2)beta(2)%3B binds two magnesium ions per tetramer%3B type 2 subfamily gene gene1336 http://www.ncbi.nlm.nih.gov/gene/?term=HI1312 HI1313 HI1313 ihfA ihfA 1391712 1392002 + integration host factor subunit alpha This protein is one of the two subunits of integration host factor%2C a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control gene gene1337 http://www.ncbi.nlm.nih.gov/gene/?term=HI1313 HI1314 HI1314 nlpC nlpC 1392055 1392540 + lipoprotein similar to GB:M14031 SP:P23898 PID:145446 GB:U00096 PID:1742788 gene gene1338 http://www.ncbi.nlm.nih.gov/gene/?term=HI1314 HI1315 HI1315 HI1315 1392718 1393023 + hypothetical protein gene gene1339 http://www.ncbi.nlm.nih.gov/gene/?term=HI1315 HI1316 HI1316 HI1316 1393010 1393996 + sulfatase-like protein gene gene1340 http://www.ncbi.nlm.nih.gov/gene/?term=HI1316 HI1317 HI1317 HI1317 1394078 1394893 + hypothetical protein similar to GB:U00096 SP:P39173 PID:1736408 PID:1742898 PID:1788080 gene gene1341 http://www.ncbi.nlm.nih.gov/gene/?term=HI1317 HI1318m HI1318m infC infC 1395026 1395568 + translation initiation factor IF-3 IF-3 has several functions that are required and promote translation initiation including%3B preventing association of 70S by binding to 30S%3B monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites%3B stimulates codon-anticodon interactions at P-site%3B involved in moving mRNA to the P-site%3B and in recycling subunits gene gene1342 http://www.ncbi.nlm.nih.gov/gene/?term=HI1318m HI1319m HI1319m rpmI rpmI 1395779 1395976 + 50S ribosomal protein L35 gene gene1343 http://www.ncbi.nlm.nih.gov/gene/?term=HI1319m HI1320 HI1320 rplT rplT 1396043 1396396 + 50S ribosomal protein L20 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit gene gene1344 http://www.ncbi.nlm.nih.gov/gene/?term=HI1320 HI1321 HI1321 recB recB 1396509 1400144 + exodeoxyribonuclease V subunit beta similar to SP:P08394 GB:X04581 GB:X04582 PID:42682 PID:763090 gene gene1345 http://www.ncbi.nlm.nih.gov/gene/?term=HI1321 HI1322 HI1322 recD recD 1400144 1402066 + exodeoxyribonuclease V subunit alpha similar to SP:P04993 GB:X04581 GB:X04582 PID:42683 PID:42691 gene gene1346 http://www.ncbi.nlm.nih.gov/gene/?term=HI1322 HI1323 HI1323 HI1323 1402135 1402581 - hypothetical protein similar to SP:P45569 GB:U00096 PID:1787190 gene gene1347 http://www.ncbi.nlm.nih.gov/gene/?term=HI1323 HI1324 HI1324 HI1324 1402678 1404483 + lon protease similar to GB:D00863 SP:P36772 PID:402504 gene gene1348 http://www.ncbi.nlm.nih.gov/gene/?term=HI1324 HI1325 HI1325 fabA fabA 1404652 1405185 + 3-hydroxydecanoyl-ACP dehydratase catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2%2C3-decenoyl-ACP or 3%2C4-decenoyl-ACP gene gene1349 http://www.ncbi.nlm.nih.gov/gene/?term=HI1325 HI1326 HI1326 HI1326 1405419 1406147 + hypothetical protein gene gene1350 http://www.ncbi.nlm.nih.gov/gene/?term=HI1326 HI1327 HI1327 HI1327 1406144 1406281 + hypothetical protein gene gene1351 http://www.ncbi.nlm.nih.gov/gene/?term=HI1327 HI1328 HI1328 rpsO rpsO 1406417 1406686 + 30S ribosomal protein S15 primary rRNA binding protein%3B helps nucleate assembly of 30S%3B binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA%3B autoregulates translation through interactions with the mRNA leader sequence gene gene1352 http://www.ncbi.nlm.nih.gov/gene/?term=HI1328 HI1329 HI1329 HI1329 1406758 1407406 - gene gene1353 http://www.ncbi.nlm.nih.gov/gene/?term=HI1329 HI1330 HI1330 dacB dacB 1407458 1408897 - D-alanyl-D-alanine carboxypeptidase/endopeptidase penicillin binding protein 4%3B penicillin sensitive%3B catalyzes the formation of D-alanine from D-alanyl-D-alanine%3B one of four%2C DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains gene gene1354 http://www.ncbi.nlm.nih.gov/gene/?term=HI1330 HI1331 HI1331 greA greA 1409061 1409537 + transcription elongation factor GreA necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites%3B arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through%2C resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus gene gene1355 http://www.ncbi.nlm.nih.gov/gene/?term=HI1331 HI1333 HI1333 yhbY yhbY 1409576 1409875 - hypothetical protein contains RNA-binding domains%3B monomeric%3B similar to SP:P42550 PID:606118 GB:U00096 PID:1789570 gene gene1356 http://www.ncbi.nlm.nih.gov/gene/?term=HI1333 HI1334 HI1334 rrmJ rrmJ 1410002 1410631 + 23S rRNA methyltransferase J Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit gene gene1357 http://www.ncbi.nlm.nih.gov/gene/?term=HI1334 HI1335 HI1335 ftsH ftsH 1410722 1412629 + cell division protein similar to GB:M83138 SP:P28691 GB:U01376 PID:146028 PID:606116 gene gene1358 http://www.ncbi.nlm.nih.gov/gene/?term=HI1335 HI1336 HI1336 folP-1 folP-1 1412741 1413568 + dihydropteroate synthase similar to GB:L06494 SP:P26282 GB:U01376 GB:X68776 GB:X68777 gene gene1359 http://www.ncbi.nlm.nih.gov/gene/?term=HI1336 HI1337 HI1337 glmM glmM 1413606 1414943 + phosphoglucosamine mutase catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate gene gene1360 http://www.ncbi.nlm.nih.gov/gene/?term=HI1337 HI1338 HI1338 HI1338 1415002 1415496 + hypothetical protein similar to GB:U00096 PID:1788681 gene gene1361 http://www.ncbi.nlm.nih.gov/gene/?term=HI1338 HI1339 HI1339 HI1339 1415698 1416087 + hypothetical protein gene gene1362 http://www.ncbi.nlm.nih.gov/gene/?term=HI1339 HI1340 HI1340 HI1340 1416165 1417490 - hypothetical protein similar to PID:882689 GB:U00096 SP:Q46920 PID:1789158 gene gene1363 http://www.ncbi.nlm.nih.gov/gene/?term=HI1340 HI1341 HI1341 HI1341 1417617 1418228 - hemoglobin-binding protein gene gene1364 http://www.ncbi.nlm.nih.gov/gene/?term=HI1341 HI1342 HI1342 HI1342 1418744 1420123 + ABC transporter ATP-binding protein similar to SP:P43672 GB:U00096 PID:1787182 PID:2251144 gene gene1366 http://www.ncbi.nlm.nih.gov/gene/?term=HI1342 HI1343 HI1343 HI1343 1418131 1418847 - hypothetical protein gene gene1365 http://www.ncbi.nlm.nih.gov/gene/?term=HI1343 HI1344 HI1344 potD potD 1420204 1421343 - spermidine/putrescine ABC transporter substrate-binding protein similar to PID:1142681 gene gene1367 http://www.ncbi.nlm.nih.gov/gene/?term=HI1344 HI1345 HI1345 potC potC 1421416 1422159 - spermidine/putrescine ABC transporter membrane protein can transport spermidine and putrescine but affinity is higher for spermidine%3B forms a complex of PotA2BCD%3B PotC is a membrane component gene gene1368 http://www.ncbi.nlm.nih.gov/gene/?term=HI1345 HI1346 HI1346 potB potB 1422185 1423045 - spermidine/putrescine ABC transporter membrane protein can transport spermidine and putrescine but affinity is higher for spermidine%3B forms a complex of PotA2BCD%3B PotB is a membrane component gene gene1369 http://www.ncbi.nlm.nih.gov/gene/?term=HI1346 HI1347 HI1347 potA potA 1423029 1424177 - putrescine/spermidine ABC transporter ATPase functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport%3B PotA is the membrane-associated ATPase gene gene1370 http://www.ncbi.nlm.nih.gov/gene/?term=HI1347 HI1348 HI1348 pepT pepT 1424443 1425681 + peptidase T catalyzes the release of the N-terminal amino acid from a tripeptide gene gene1371 http://www.ncbi.nlm.nih.gov/gene/?term=HI1348 HI1349 HI1349 HI1349 1426245 1426727 - hypothetical protein similar to PID:1652428 gene gene1372 http://www.ncbi.nlm.nih.gov/gene/?term=HI1349 HI1350 HI1350 cdd cdd 1427001 1427879 + cytidine deaminase Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis gene gene1373 http://www.ncbi.nlm.nih.gov/gene/?term=HI1350 HI1351 HI1351 HI1351 1427922 1428887 - hypothetical protein similar to GB:U00096 PID:1788178 gene gene1374 http://www.ncbi.nlm.nih.gov/gene/?term=HI1351 HI1352 HI1352 putP putP 1428884 1430398 - sodium/proline symporter proline permease%3B similar to GB:D32069 PID:509694 PID:913690 gene gene1375 http://www.ncbi.nlm.nih.gov/gene/?term=HI1352 HI1353 HI1353 cafA cafA 1430514 1431989 + ribonuclease G involved in the processing of the 5'end of 16S rRNA gene gene1376 http://www.ncbi.nlm.nih.gov/gene/?term=HI1353 HI1354 HI1354 glnS glnS 1432409 1434082 + glutamine--tRNA ligase catalyzes a two-step reaction%2C first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA gene gene1377 http://www.ncbi.nlm.nih.gov/gene/?term=HI1354 HI1355 HI1355 HI1355 1434148 1434612 + hypothetical protein similar to GB:U00096 PID:1787429 gene gene1378 http://www.ncbi.nlm.nih.gov/gene/?term=HI1355 HI1356 HI1356 malQ malQ 1434674 1436773 + 4-alpha-glucanotransferase similar to GB:M32793 SP:P15977 PID:146715 PID:606351 GB:U00096 gene gene1379 http://www.ncbi.nlm.nih.gov/gene/?term=HI1356 HI1357 HI1357 glgB glgB 1436783 1438975 + glycogen branching protein catalyzes the transfer of a segment of a 1%2C4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain gene gene1380 http://www.ncbi.nlm.nih.gov/gene/?term=HI1357 HI1358 HI1358 glgX glgX 1439071 1441050 + glycogen operon protein similar to GB:J01616 SP:P15067 PID:146135 PID:606366 GB:U00096 gene gene1381 http://www.ncbi.nlm.nih.gov/gene/?term=HI1358 HI1359 HI1359 glgC glgC 1441040 1442374 + glucose-1-phosphate adenylyltransferase catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate gene gene1382 http://www.ncbi.nlm.nih.gov/gene/?term=HI1359 HI1360 HI1360 glgA glgA 1442482 1443912 + glycogen synthase catalyzes the formation of alpha-1%2C4-glucan chains from ADP-glucose gene gene1383 http://www.ncbi.nlm.nih.gov/gene/?term=HI1360 HI1361 HI1361 HI1361 1444158 1446623 + hypothetical protein similar to GB:J03966 SP:P13031 GB:M22368 GB:X16931 PID:146146 gene gene1384 http://www.ncbi.nlm.nih.gov/gene/?term=HI1361 HI1362 HI1362 pntA pntA 1446885 1448423 + NAD(P) transhydrogenase subunit alpha forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane%3B involved in catalyzing transfer of hydride ion equivalents between NAD and NADP%3B stereospecific (AB-specific)%3B functions as a proton pump by translocating protons from cytoplasm to periplasm gene gene1385 http://www.ncbi.nlm.nih.gov/gene/?term=HI1362 HI1363 HI1363 pntB pntB 1448434 1449858 + pyridine nucleotide transhydrogenase catalyzes reversible transfer of hydride ion equivalent between NAD and NADP%3B membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane%3B forms a tetramer composed of two alpha and 2 beta subunits%3B AB-stereospecific enzyme gene gene1386 http://www.ncbi.nlm.nih.gov/gene/?term=HI1363 HI1364 HI1364 HI1364 1449976 1450842 - transcriptional regulator similar to SP:P37641 PID:466658 GB:U00096 PID:1789938 gene gene1387 http://www.ncbi.nlm.nih.gov/gene/?term=HI1364 HI1365 HI1365 topA topA 1450938 1453544 + DNA topoisomerase I catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining%2C maintains net negative superhelicity gene gene1388 http://www.ncbi.nlm.nih.gov/gene/?term=HI1365 HI1366 HI1366 acpD acpD 1453620 1454204 - acyl carrier protein phosphodiesterase similar to GB:U00096 PID:1742298 PID:1742303 PID:1787680 gene gene1389 http://www.ncbi.nlm.nih.gov/gene/?term=HI1366 HI1367 HI1367 thrS thrS 1454489 1456420 + threonine--tRNA ligase catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr)%3B catalyzes a two-step reaction%2C first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA gene gene1390 http://www.ncbi.nlm.nih.gov/gene/?term=HI1367 HI1368 HI1368 HI1368 1456539 1459319 - zinc protease similar to SP:P31828 GB:X71917 PID:535004 GB:U00096 PID:1742451 gene gene1391 http://www.ncbi.nlm.nih.gov/gene/?term=HI1368 HI1369 HI1369 HI1369 1459423 1461942 - hypothetical protein similar to SP:P31827 GB:X71917 PID:311346 GB:U00096 PID:1787771 gene gene1392 http://www.ncbi.nlm.nih.gov/gene/?term=HI1369 HI1370 HI1370 mopI mopI 1461986 1462195 - molybdenum-pterin binding protein similar to GB:M17157 SP:P04952 SP:P08854 GB:M17158 GB:X04982 gene gene1393 http://www.ncbi.nlm.nih.gov/gene/?term=HI1370 HI1371 HI1371 HI1371 1462303 1462632 - sulfurtransferase TusE similar to GB:L05610 SP:P45573 PID:145087 gene gene1394 http://www.ncbi.nlm.nih.gov/gene/?term=HI1371 HI1371.1 HI1371.1 HI1371.1 1462634 1463575 - C32 tRNA thiolase TtcA%3B YdaO%3B catalyzes the thiolation of cytosine 32 in specific tRNAs gene gene1395 http://www.ncbi.nlm.nih.gov/gene/?term=HI1371.1 HI1372 HI1372 kicB kicB 1463725 1465059 + condesin subunit F acts with MukB and MukE to condense the chromosome and allow for segregation during cell division gene gene1396 http://www.ncbi.nlm.nih.gov/gene/?term=HI1372 HI1373 HI1373 kicA kicA 1465106 1465837 + condesin subunit E acts with MukB and MukF to condense the chromosome and allow for segregation during cell division gene gene1397 http://www.ncbi.nlm.nih.gov/gene/?term=HI1373 HI1374 HI1374 mukB mukB 1465837 1470369 + cell division protein MukB SMC (structural maintenance of chromosomes) family of proteins%3B involved in chromosome condensatin and partitioning%3B forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ%3B mutations result in cell division defects gene gene1398 http://www.ncbi.nlm.nih.gov/gene/?term=HI1374 HI1375 HI1375 HI1375 1470440 1471348 + hypothetical protein gene gene1399 http://www.ncbi.nlm.nih.gov/gene/?term=HI1375 HI1376 HI1376 HI1376 1471351 1472226 + hypothetical protein gene gene1400 http://www.ncbi.nlm.nih.gov/gene/?term=HI1376 HI1377 HI1377 sbcB sbcB 1472239 1473660 + exonuclease I Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates gene gene1401 http://www.ncbi.nlm.nih.gov/gene/?term=HI1377 HI1378 HI1378 phoR phoR 1474351 1475628 - phosphate regulon sensor protein PhoR similar to SP:P08400 GB:X04704 PID:581188 GB:U00096 PID:1657596 gene gene1402 http://www.ncbi.nlm.nih.gov/gene/?term=HI1378 HI1379 HI1379 phoB phoB 1475625 1476320 - phosphate regulon transcriptional regulatory protein PhoB similar to SP:P08402 GB:X04026 PID:42388 GB:U00096 PID:1657595 gene gene1403 http://www.ncbi.nlm.nih.gov/gene/?term=HI1379 HI1380 HI1380 pstB pstB 1476415 1477183 - gene gene1404 http://www.ncbi.nlm.nih.gov/gene/?term=HI1380 HI1381 HI1381 pstA pstA 1477193 1478041 - phosphate ABC transporter permease similar to GB:L10328 SP:P07654 GB:K01992 GB:X02723 PID:147258 gene gene1405 http://www.ncbi.nlm.nih.gov/gene/?term=HI1381 HI1382 HI1382 pstC pstC 1478043 1478990 - phosphate ABC transporter permease similar to GB:L10328 SP:P07653 GB:K01992 GB:X02723 PID:147257 gene gene1406 http://www.ncbi.nlm.nih.gov/gene/?term=HI1382 HI1383m HI1383m pstS pstS 1479081 1480084 - phosphate ABC transporter substrate-binding protein gene gene1407 http://www.ncbi.nlm.nih.gov/gene/?term=HI1383m HI1384 HI1384 rsgA rsgA 1480541 1481089 + ferritin like protein 1 similar to SP:P23887 GB:X53513 PID:42898 GB:U00096 PID:1736567 gene gene1408 http://www.ncbi.nlm.nih.gov/gene/?term=HI1384 HI1385 HI1385 rsgA rsgA 1481105 1481602 + ferritin similar to SP:P23887 GB:X53513 PID:42898 GB:U00096 PID:1736567 gene gene1409 http://www.ncbi.nlm.nih.gov/gene/?term=HI1385 HI1386 HI1386 HI1386 1481976 1482422 + hypothetical protein gene gene1410 http://www.ncbi.nlm.nih.gov/gene/?term=HI1386 HI1387 HI1387 trpE trpE 1482528 1484084 + anthranilate synthase component I with component II%2C the glutamine amidotransferase%2C catalyzes the formation of anthranilate from chorismate and glutamine gene gene1411 http://www.ncbi.nlm.nih.gov/gene/?term=HI1387 HI1388 HI1388 trpG trpG 1484097 1484678 + anthranilate synthase component II TrpG%3B with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine%3B TrpG provides the glutamine amidotransferase activity gene gene1412 http://www.ncbi.nlm.nih.gov/gene/?term=HI1388 HI1388.1 HI1388.1 HI1388.1 1484727 1485113 + hypothetical protein gene gene1413 http://www.ncbi.nlm.nih.gov/gene/?term=HI1388.1 HI1389 HI1389 trpD trpD 1485166 1486167 + anthranilate phosphoribosyltransferase Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate gene gene1414 http://www.ncbi.nlm.nih.gov/gene/?term=HI1389 HI1389.1 HI1389.1 trpC trpC 1486204 1487637 + bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase monomeric bifunctional protein%3B functions in tryptophan biosynthesis pathway%3B phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate gene gene1415 http://www.ncbi.nlm.nih.gov/gene/?term=HI1389.1 HI1390 HI1390 hybG hybG 1487697 1487971 + hydrogenase 2 accessory protein gene gene1416 http://www.ncbi.nlm.nih.gov/gene/?term=HI1390 HI1391 HI1391 valS valS 1488005 1490869 - valine--tRNA ligase valine--tRNA ligase%3B ValRS%3B converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val)%3B class-I aminoacyl-tRNA synthetase type 1 subfamily%3B has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain gene gene1417 http://www.ncbi.nlm.nih.gov/gene/?term=HI1391 HI1392 HI1392 hindIIIM hindIIIM 1490870 1491799 - modification methylase similar to GB:L15391 PID:1574226 gene gene1418 http://www.ncbi.nlm.nih.gov/gene/?term=HI1392 HI1393 HI1393 hindIIIR hindIIIR 1491780 1492682 - type II restriction endonuclease similar to GB:L15391 PID:1574230 gene gene1419 http://www.ncbi.nlm.nih.gov/gene/?term=HI1393 HI1394 HI1394 HI1394 1492630 1493001 - hypothetical protein similar to PID:887850 GB:U00096 SP:Q46828 PID:1789267 gene gene1420 http://www.ncbi.nlm.nih.gov/gene/?term=HI1394 HI1395 HI1395 HI1395 1493028 1493621 - gene gene1421 http://www.ncbi.nlm.nih.gov/gene/?term=HI1395 HI1397 HI1397 holC holC 1493866 1494300 - DNA polymerase III subunit chi binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB gene gene1422 http://www.ncbi.nlm.nih.gov/gene/?term=HI1397 HI1398 HI1398 fumC fumC 1494535 1495929 + fumarate hydratase class II family (does not require metal)%3B tetrameric enzyme%3B fumarase C%3B reversibly converts (S)-malate to fumarate and water%3B functions in the TCA cycle gene gene1423 http://www.ncbi.nlm.nih.gov/gene/?term=HI1398 HI1399 HI1399 HI1399 1496057 1496665 + hypothetical protein gene gene1424 http://www.ncbi.nlm.nih.gov/gene/?term=HI1399 HI1400 HI1400 HI1400 1496764 1497588 - hypothetical protein similar to GB:U00096 PID:1787520 gene gene1425 http://www.ncbi.nlm.nih.gov/gene/?term=HI1400 HI1401 HI1401 pyrD pyrD 1497588 1498607 - dihydroorotate dehydrogenase 2 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway%3B uses a flavin nucleotide as an essential cofactor%3B class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus%2C which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors gene gene1426 http://www.ncbi.nlm.nih.gov/gene/?term=HI1401 HI1403 HI1403 yhxB yhxB 1499076 1499624 - tail fiber protein/phosphomannomutase gene gene1427 http://www.ncbi.nlm.nih.gov/gene/?term=HI1403 HI1405 HI1405 HI1405 1500122 1501222 - hypothetical protein gene gene1428 http://www.ncbi.nlm.nih.gov/gene/?term=HI1405 HI1406 HI1406 HI1406 1501283 1501639 - hypothetical protein gene gene1429 http://www.ncbi.nlm.nih.gov/gene/?term=HI1406 HI1407 HI1407 HI1407 1502127 1503470 - plasmid RP4 TraN-like protein similar to GB:L10330 PID:437700 gene gene1430 http://www.ncbi.nlm.nih.gov/gene/?term=HI1407 HI1409 HI1409 HI1409 1503394 1504704 - hypothetical protein gene gene1431 http://www.ncbi.nlm.nih.gov/gene/?term=HI1409 HI1410 HI1410 HI1410 1504706 1505890 - terminase large subunit-like protein gene gene1432 http://www.ncbi.nlm.nih.gov/gene/?term=HI1410 HI1411 HI1411 HI1411 1506035 1506550 - terminase small subunit similar to SP:Q38627 PID:522116 gene gene1433 http://www.ncbi.nlm.nih.gov/gene/?term=HI1411 HI1412 HI1412 HI1412 1506560 1507081 - hypothetical protein similar to SP:P21417 PID:1196685 gene gene1434 http://www.ncbi.nlm.nih.gov/gene/?term=HI1412 HI1413 HI1413 HI1413 1507209 1507490 - hypothetical protein gene gene1435 http://www.ncbi.nlm.nih.gov/gene/?term=HI1413 HI1414 HI1414 HI1414 1507402 1507677 - hypothetical protein gene gene1436 http://www.ncbi.nlm.nih.gov/gene/?term=HI1414 HI1415 HI1415 HI1415 1507670 1508272 - hypothetical protein gene gene1437 http://www.ncbi.nlm.nih.gov/gene/?term=HI1415 HI1416 HI1416 HI1416 1508241 1508597 - hypothetical protein gene gene1438 http://www.ncbi.nlm.nih.gov/gene/?term=HI1416 HI1418 HI1418 HI1418 1509035 1509601 - hypothetical protein gene gene1439 http://www.ncbi.nlm.nih.gov/gene/?term=HI1418 HI1419 HI1419 HI1419 1509962 1510261 + hypothetical protein gene gene1440 http://www.ncbi.nlm.nih.gov/gene/?term=HI1419 HI1420 HI1420 HI1420 1510258 1510551 + hypothetical protein gene gene1441 http://www.ncbi.nlm.nih.gov/gene/?term=HI1420 HI1422 HI1422 HI1422 1511013 1511588 + hypothetical protein gene gene1442 http://www.ncbi.nlm.nih.gov/gene/?term=HI1422 HI1423 HI1423 HI1423 1511874 1512158 + hypothetical protein gene gene1443 http://www.ncbi.nlm.nih.gov/gene/?term=HI1423 HI1424 HI1424 HI1424 1512159 1513073 - integrase/recombinase similar to SP:P10487 GB:D90039 SP:P16470 GB:AB027308 GB:AB027308 gene gene1444 http://www.ncbi.nlm.nih.gov/gene/?term=HI1424 HI1424.1 HI1424.1 HI1424.1 1513211 1513296 - tRNA-Leu tRNA gene1445 http://www.ncbi.nlm.nih.gov/gene/?term=HI1424.1 HI1425 HI1425 fnr fnr 1513585 1514358 + fumarate/nitrate reduction transcriptional regulator Global transcription factor that controls the expression of over 100 target genes in response to anoxia gene gene1446 http://www.ncbi.nlm.nih.gov/gene/?term=HI1425 HI1426 HI1426 HI1426 1514479 1515408 + universal stress protein UspE with UspC and UspD is involved in resistance to UV irradiation gene gene1447 http://www.ncbi.nlm.nih.gov/gene/?term=HI1426 HI1427 HI1427 HI1427 1515608 1516444 + hypothetical protein gene gene1448 http://www.ncbi.nlm.nih.gov/gene/?term=HI1427 HI1428 HI1428 purN purN 1516529 1517167 - phosphoribosylglycinamide formyltransferase glycinamide ribonucleotide transformylase%3B GAR Tfase%3B catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate%3B PurN requires formyl folate for the reaction unlike PurT which uses formate gene gene1449 http://www.ncbi.nlm.nih.gov/gene/?term=HI1428 HI1429 HI1429 purM purM 1517222 1518256 - phosphoribosylaminoimidazole synthetase catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis gene gene1450 http://www.ncbi.nlm.nih.gov/gene/?term=HI1429 HI1430 HI1430 HI1430 1518436 1519194 + short chain dehydrogenase/reductase similar to GB:U00096 PID:1787820 gene gene1451 http://www.ncbi.nlm.nih.gov/gene/?term=HI1430 HI1431 HI1431 trpB trpB 1519211 1520404 + tryptophan synthase subunit beta catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate gene gene1452 http://www.ncbi.nlm.nih.gov/gene/?term=HI1431 HI1432 HI1432 trpA trpA 1520404 1521210 + tryptophan synthase subunit alpha catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis gene gene1453 http://www.ncbi.nlm.nih.gov/gene/?term=HI1432 HI1433 HI1433 usg1 usg1 1521348 1522301 - aspartate-semialdehyde dehydrogenase catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde gene gene1454 http://www.ncbi.nlm.nih.gov/gene/?term=HI1433 HI1434 HI1434 ybaK ybaK 1522360 1522836 + hypothetical protein contains a C-type lectin fold%3B similar to prolyl-tRNA synthetases%3B similar to GB:L23802 SP:P36922 PID:388109 gene gene1455 http://www.ncbi.nlm.nih.gov/gene/?term=HI1434 HI1434.1 HI1434.1 cspD cspD 1522993 1523211 - cold shock-like protein similar to SP:P24245 GB:U00096 PID:1651400 PID:1787107 gene gene1456 http://www.ncbi.nlm.nih.gov/gene/?term=HI1434.1 HI1434.2 HI1434.2 HI1434.2 1523361 1523519 - hypothetical protein similar to GB:U00096 PID:1788113 gene gene1457 http://www.ncbi.nlm.nih.gov/gene/?term=HI1434.2 HI1435 HI1435 HI1435 1523512 1524232 - gene gene1458 http://www.ncbi.nlm.nih.gov/gene/?term=HI1435 HI1436 HI1436 HI1436 1524226 1524546 - hypothetical protein similar to PID:882688 GB:U00096 PID:882687 gene gene1459 http://www.ncbi.nlm.nih.gov/gene/?term=HI1436 HI1436.1 HI1436.1 thiI thiI 1524561 1526019 - gene gene1460 http://www.ncbi.nlm.nih.gov/gene/?term=HI1436.1 HI1437 HI1437 xseB xseB 1526179 1526433 + exodeoxyribonuclease VII small subunit catalyzes the bidirectional exonucleolytic cleavage of DNA gene gene1461 http://www.ncbi.nlm.nih.gov/gene/?term=HI1437 HI1438 HI1438 ispA ispA 1526433 1527320 + geranyltranstransferase similar to GB:D00694 SP:P22939 PID:216584 GB:U00096 PID:1773105 gene gene1462 http://www.ncbi.nlm.nih.gov/gene/?term=HI1438 HI1439 HI1439 dxs dxs 1527362 1529239 + 1-deoxy-D-xylulose-5-phosphate synthase catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate gene gene1463 http://www.ncbi.nlm.nih.gov/gene/?term=HI1439 HI1440 HI1440 sspB sspB 1529275 1529727 - ClpXP protease specificity-enhancing factor similar to GB:M69028 SP:P25663 GB:X05088 PID:147872 PID:42999 gene gene1464 http://www.ncbi.nlm.nih.gov/gene/?term=HI1440 HI1441 HI1441 sspA sspA 1529727 1530365 - stringent starvation protein A similar to SP:P31784 PID:241868 gene gene1465 http://www.ncbi.nlm.nih.gov/gene/?term=HI1441 HI1442 HI1442 rpsI rpsI 1530546 1530938 - 30S ribosomal protein S9 forms a direct contact with the tRNA during translation gene gene1466 http://www.ncbi.nlm.nih.gov/gene/?term=HI1442 HI1443 HI1443 rplM rplM 1530955 1531383 - 50S ribosomal protein L13 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit gene gene1467 http://www.ncbi.nlm.nih.gov/gene/?term=HI1443 HI1444 HI1444 metF metF 1531847 1532725 + 5%2C10-methylenetetrahydrofolate reductase MTHFR%3B catalyzes NADH-linked reduction of 5%2C10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor gene gene1468 http://www.ncbi.nlm.nih.gov/gene/?term=HI1444 HI1445 HI1445 bioD bioD 1532814 1533542 - dithiobiotin synthetase DTB synthetase%3B dethiobiotin synthase%3B involved in production of dethiobiotin from ATP and 7%2C8-diaminononanoate and carbon dioxide%3B contains magnesium gene gene1469 http://www.ncbi.nlm.nih.gov/gene/?term=HI1445 HI1446 HI1446 HI1446 1533645 1533968 - hypothetical protein similar to GB:U00096 PID:1787427 gene gene1470 http://www.ncbi.nlm.nih.gov/gene/?term=HI1446 HI1447 HI1447 folE folE 1533972 1534628 - GTP cyclohydrolase I involved in the first step of tetrahydrofolate biosynthesis%3B catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1%2C2%2C3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water%3B forms a homopolymer gene gene1471 http://www.ncbi.nlm.nih.gov/gene/?term=HI1447 HI1448 HI1448 moeA moeA 1534766 1535980 + molybdopterin biosynthesis protein similar to GB:M21151 SP:P12281 PID:145539 GB:U00096 PID:1651376 gene gene1472 http://www.ncbi.nlm.nih.gov/gene/?term=HI1448 HI1449 HI1449 moeB moeB 1535984 1536715 + molybdopterin biosynthesis protein MoeB ATP-dependent adenylate transferase%2C transfers adenyl moiety to the MoeD subunit of molybdopterin synthase gene gene1473 http://www.ncbi.nlm.nih.gov/gene/?term=HI1449 HI1450 HI1450 HI1450 1536782 1537105 + dsDNA-mimic protein highly acidic protein%3B the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi)%3B binds heat-unstable protein (HU-alpha) which is a histone-like protein gene gene1474 http://www.ncbi.nlm.nih.gov/gene/?term=HI1450 HI1452 HI1452 HI1452 1537173 1537760 - hypothetical protein gene gene1475 http://www.ncbi.nlm.nih.gov/gene/?term=HI1452 HI1453 HI1453 purL purL 1537998 1538468 - phosphoribosylformylglycinamidine synthase similar to GB:AL009126 gene gene1476 http://www.ncbi.nlm.nih.gov/gene/?term=HI1453 HI1454 HI1454 HI1454 1538510 1539151 - hypothetical protein similar to SP:P45706 PID:870925 PID:1405449 GB:AL009126 gene gene1477 http://www.ncbi.nlm.nih.gov/gene/?term=HI1454 HI1455 HI1455 msrA msrA 1539163 1540224 - bifunctional methionine sulfoxide reductase subunits A/B this fusion consists of methionine sulfoxide A reductase at the N-terminus and B at the C-terminus%3B A and B are stereospecific enzymes that recognize the damaged produces of oxidative stress%2C S and R epimers of methionine sulfoxide%2C respectively%3B a fusion gene gene1478 http://www.ncbi.nlm.nih.gov/gene/?term=HI1455 HI1456 HI1456 HI1456 1540419 1540868 - hypothetical protein gene gene1479 http://www.ncbi.nlm.nih.gov/gene/?term=HI1456 HI1457 HI1457 HI1457 1540879 1541415 - opacity protein similar to PID:2367659 gene gene1480 http://www.ncbi.nlm.nih.gov/gene/?term=HI1457 HI1458m HI1458m HI1458m 1541571 1541953 + gene gene1481 http://www.ncbi.nlm.nih.gov/gene/?term=HI1458m HI1459 HI1459 HI1459 1542231 1542776 - RNA polymerase sigma factor Bacteria have multiple sigma factors which are active under specific conditions%3B the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription gene gene1482 http://www.ncbi.nlm.nih.gov/gene/?term=HI1459 HI1459.1 HI1459.1 HI1459.1 1542998 1543680 - gene gene1483 http://www.ncbi.nlm.nih.gov/gene/?term=HI1459.1 HI1462 HI1462 HI1462 1544081 1545445 + hypothetical protein similar to GB:U00096 SP:P77211 PID:1778487 PID:1786785 gene gene1484 http://www.ncbi.nlm.nih.gov/gene/?term=HI1462 HI1462.1 HI1462.1 HI1462.1 1545523 1545912 - hypothetical protein gene gene1485 http://www.ncbi.nlm.nih.gov/gene/?term=HI1462.1 HI1462.2 HI1462.2 HI1462.2 1546114 1546608 - hypothetical protein similar to GB:U00096 PID:1788681 gene gene1486 http://www.ncbi.nlm.nih.gov/gene/?term=HI1462.2 HI1463 HI1463 glmM glmM 1546667 1548004 - phosphoglucosamine mutase catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate gene gene1487 http://www.ncbi.nlm.nih.gov/gene/?term=HI1463 HI1464 HI1464 folP-2 folP-2 1548042 1548869 - dihydropteroate synthase similar to GB:L06494 SP:P26282 GB:U01376 GB:X68776 GB:X68777 gene gene1488 http://www.ncbi.nlm.nih.gov/gene/?term=HI1464 HI1465 HI1465 HI1465 1548981 1550126 - cell division FtsH-like protein similar to GB:M83138 SP:P28691 GB:U01376 PID:146028 PID:606116 gene gene1489 http://www.ncbi.nlm.nih.gov/gene/?term=HI1465 HI1466m HI1466m HI1466m 1550264 1552466 + gene gene1490 http://www.ncbi.nlm.nih.gov/gene/?term=HI1466m HI1467 HI1467 HI1467 1552525 1554294 + ABC transporter ATP-binding protein similar to SP:Q50614 PID:1483552 gene gene1491 http://www.ncbi.nlm.nih.gov/gene/?term=HI1467 HI1468 HI1468 rpsO rpsO 1554432 1554701 - 30S ribosomal protein S15 primary rRNA binding protein%3B helps nucleate assembly of 30S%3B binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA%3B autoregulates translation through interactions with the mRNA leader sequence gene gene1492 http://www.ncbi.nlm.nih.gov/gene/?term=HI1468 HI1470 HI1470 HI1470 1555042 1555803 - iron chelatin ABC transporter ATP-binding protein similar to GB:AE000511 SP:O05732 PID:2072456 PID:2314024 gene gene1493 http://www.ncbi.nlm.nih.gov/gene/?term=HI1470 HI1471 HI1471 HI1471 1555796 1556809 - ABC transporter permease similar to GB:AE000511 SP:O05731 PID:2072455 PID:2314025 gene gene1494 http://www.ncbi.nlm.nih.gov/gene/?term=HI1471 HI1472 HI1472 HI1472 1556796 1557851 - iron chelatin ABC transporter substrate-binding protein similar to GB:AE000511 PID:2314746 gene gene1495 http://www.ncbi.nlm.nih.gov/gene/?term=HI1472 HI1473 HI1473 modD modD 1557919 1558764 - molybdenum transport protein ModD involved in molybdenum transport gene gene1496 http://www.ncbi.nlm.nih.gov/gene/?term=HI1473 HI1474 HI1474 HI1474 1558774 1559373 - ABC transporter ATP-binding protein similar to GB:AE000511 PID:2313950 gene gene1497 http://www.ncbi.nlm.nih.gov/gene/?term=HI1474 HI1475 HI1475 HI1475 1559375 1559734 - hypothetical protein gene gene1498 http://www.ncbi.nlm.nih.gov/gene/?term=HI1475 HI1476 HI1476 HI1476 1559962 1560681 - transcriptional regulatory protein similar to SP:Q37906 PID:403436 gene gene1499 http://www.ncbi.nlm.nih.gov/gene/?term=HI1476 HI1477 HI1477 ner ner 1560909 1561178 + DNA-binding protein similar to SP:P06903 gene gene1500 http://www.ncbi.nlm.nih.gov/gene/?term=HI1477 HI1478 HI1478 muA muA 1561212 1563275 + transposase similar to SP:P07636 PID:15450 PID:15810 PID:215511 PID:215547 gene gene1501 http://www.ncbi.nlm.nih.gov/gene/?term=HI1478 HI1479 HI1479 HI1479 1563332 1563604 + hypothetical protein gene gene1502 http://www.ncbi.nlm.nih.gov/gene/?term=HI1479 HI1480 HI1480 HI1480 1563537 1564007 - hypothetical protein gene gene1503 http://www.ncbi.nlm.nih.gov/gene/?term=HI1480 HI1481 HI1481 muB muB 1564041 1564904 + DNA transposition protein similar to SP:P03763 PID:15448 PID:215512 PID:215550 gene gene1504 http://www.ncbi.nlm.nih.gov/gene/?term=HI1481 HI1482 HI1482 HI1482 1564965 1565282 + hypothetical protein gene gene1505 http://www.ncbi.nlm.nih.gov/gene/?term=HI1482 HI1483 HI1483 gam gam 1565297 1565806 + host-nuclease inhibitor protein similar to SP:P06023 PID:15461 PID:215562 gene gene1506 http://www.ncbi.nlm.nih.gov/gene/?term=HI1483 HI1485 HI1485 HI1485 1566436 1566657 + hypothetical protein gene gene1507 http://www.ncbi.nlm.nih.gov/gene/?term=HI1485 HI1486 HI1486 HI1486 1566657 1566830 + hypothetical protein gene gene1508 http://www.ncbi.nlm.nih.gov/gene/?term=HI1486 HI1487 HI1487 HI1487 1566833 1567393 + hypothetical protein gene gene1509 http://www.ncbi.nlm.nih.gov/gene/?term=HI1487 HI1488 HI1488 HI1488 1567567 1568124 + hypothetical protein similar to PID:215574 gene gene1510 http://www.ncbi.nlm.nih.gov/gene/?term=HI1488 HI1489 HI1489 HI1489 1568121 1568675 + hypothetical protein gene gene1511 http://www.ncbi.nlm.nih.gov/gene/?term=HI1489 HI1491m HI1491m mor mor 1568867 1569300 + gene gene1512 http://www.ncbi.nlm.nih.gov/gene/?term=HI1491m HI1492 HI1492 HI1492 1569309 1569815 + hypothetical protein gene gene1513 http://www.ncbi.nlm.nih.gov/gene/?term=HI1492 HI1493 HI1493 HI1493 1569897 1570181 + hypothetical protein gene gene1514 http://www.ncbi.nlm.nih.gov/gene/?term=HI1493 HI1495 HI1495 HI1495 1570448 1570708 + hypothetical protein gene gene1515 http://www.ncbi.nlm.nih.gov/gene/?term=HI1495 HI1496 HI1496 HI1496 1570705 1570959 + hypothetical protein gene gene1516 http://www.ncbi.nlm.nih.gov/gene/?term=HI1496 HI1497 HI1497 HI1497 1571077 1571304 + hypothetical protein similar to SP:Q06424 PID:288658 gene gene1517 http://www.ncbi.nlm.nih.gov/gene/?term=HI1497 HI1498 HI1498 HI1498 1571211 1571630 + hypothetical protein gene gene1518 http://www.ncbi.nlm.nih.gov/gene/?term=HI1498 HI1498.1 HI1498.1 HI1498.1 1571635 1571943 + hypothetical protein gene gene1519 http://www.ncbi.nlm.nih.gov/gene/?term=HI1498.1 HI1499 HI1499 HI1499 1571955 1572524 + hypothetical protein gene gene1520 http://www.ncbi.nlm.nih.gov/gene/?term=HI1499 HI1500 HI1500 HI1500 1572524 1574050 + hypothetical protein gene gene1521 http://www.ncbi.nlm.nih.gov/gene/?term=HI1500 HI1501 HI1501 HI1501 1574062 1575624 + hypothetical protein gene gene1522 http://www.ncbi.nlm.nih.gov/gene/?term=HI1501 HI1502 HI1502 HI1502 1575715 1576959 + hypothetical protein gene gene1523 http://www.ncbi.nlm.nih.gov/gene/?term=HI1502 HI1502.1 HI1502.1 HI1502.1 1576960 1577041 - tRNA-OTHER tRNA-pseudo tRNA gene1524 http://www.ncbi.nlm.nih.gov/gene/?term=HI1502.1 HI1503 HI1503 HI1503 1577097 1577537 + Mu-like prophage FluMu G protein similar to bacteriophage Mu G-1 protein%3B SP:Q01261 PID:215535 gene gene1525 http://www.ncbi.nlm.nih.gov/gene/?term=HI1503 HI1504 HI1504 HI1504 1577768 1578835 + bacteriophage Mu I protein similar to bacteriophage Mu I protein%3B similar to SP:Q01267 PID:215536 gene gene1526 http://www.ncbi.nlm.nih.gov/gene/?term=HI1504 HI1505 HI1505 HI1505 1578835 1579761 + hypothetical protein gene gene1527 http://www.ncbi.nlm.nih.gov/gene/?term=HI1505 HI1506 HI1506 HI1506 1579844 1580229 + gene gene1528 http://www.ncbi.nlm.nih.gov/gene/?term=HI1506 HI1508 HI1508 HI1508 1580232 1580657 + hypothetical protein similar to PID:2353778 gene gene1529 http://www.ncbi.nlm.nih.gov/gene/?term=HI1508 HI1509 HI1509 HI1509 1580657 1581208 + hypothetical protein similar to PID:2353777 gene gene1530 http://www.ncbi.nlm.nih.gov/gene/?term=HI1509 HI1510 HI1510 HI1510 1581221 1581412 + hypothetical protein similar to PID:1834290 gene gene1531 http://www.ncbi.nlm.nih.gov/gene/?term=HI1510 HI1511 HI1511 HI1511 1581412 1582875 + sheath protein gpL similar to bacteriophage Mu L protein%3B PID:1834291 gene gene1532 http://www.ncbi.nlm.nih.gov/gene/?term=HI1511 HI1512 HI1512 HI1512 1582885 1583241 + hypothetical protein similar to PID:1834292 gene gene1533 http://www.ncbi.nlm.nih.gov/gene/?term=HI1512 HI1513 HI1513 HI1513 1583254 1583637 + hypothetical protein similar to PID:1834293 gene gene1534 http://www.ncbi.nlm.nih.gov/gene/?term=HI1513 HI1514 HI1514 HI1514 1583718 1585613 + monofunctional biosynthetic peptidoglycan transglycosylase gene gene1535 http://www.ncbi.nlm.nih.gov/gene/?term=HI1514 HI1515 HI1515 muN muN 1585613 1586980 + 64 kDa virion protein similar to SP:P08557 PID:15105 gene gene1536 http://www.ncbi.nlm.nih.gov/gene/?term=HI1515 HI1516m HI1516m HI1516m 1586980 1588240 + gene gene1537 http://www.ncbi.nlm.nih.gov/gene/?term=HI1516m HI1518 HI1518 HI1518 1588277 1588825 + hypothetical protein gene gene1538 http://www.ncbi.nlm.nih.gov/gene/?term=HI1518 HI1519 HI1519 HI1519 1588834 1589241 + hypothetical protein gene gene1539 http://www.ncbi.nlm.nih.gov/gene/?term=HI1519 HI1520 HI1520 HI1520 1589241 1590308 + hypothetical protein similar to GB:U00096 PID:1787398 gene gene1540 http://www.ncbi.nlm.nih.gov/gene/?term=HI1520 HI1521 HI1521 HI1521 1590340 1590900 + hypothetical protein similar to GB:U00096 PID:1787399 gene gene1541 http://www.ncbi.nlm.nih.gov/gene/?term=HI1521 HI1522 HI1522 HI1522 1590900 1592771 + hypothetical protein gene gene1542 http://www.ncbi.nlm.nih.gov/gene/?term=HI1522 HI1522.1 HI1522.1 HI1522.1 1593255 1593374 + hypothetical protein gene gene1543 http://www.ncbi.nlm.nih.gov/gene/?term=HI1522.1 HI1523 HI1523 HI1523 1593385 1594275 + hypothetical protein gene gene1544 http://www.ncbi.nlm.nih.gov/gene/?term=HI1523 HI1525 HI1525 HI1525 1594829 1595566 - molybdate-binding periplasmic protein similar to GB:AE000666 gene gene1545 http://www.ncbi.nlm.nih.gov/gene/?term=HI1525 HI1526 HI1526 rfaE rfaE 1595753 1597183 - bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D%2CD-heptose-1%2C7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D%2CD-heptose gene gene1546 http://www.ncbi.nlm.nih.gov/gene/?term=HI1526 HI1527 HI1527 htrB htrB 1597280 1598215 + lipid A biosynthesis lauroyl acyltransferase Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA gene gene1547 http://www.ncbi.nlm.nih.gov/gene/?term=HI1527 HI1528 HI1528 parE parE 1598289 1600187 + DNA topoisomerase IV subunit B decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling gene gene1548 http://www.ncbi.nlm.nih.gov/gene/?term=HI1528 HI1529 HI1529 parC parC 1600254 1602497 + DNA topoisomerase IV subunit A decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling gene gene1549 http://www.ncbi.nlm.nih.gov/gene/?term=HI1529 HI1530 HI1530 gltS gltS 1602539 1603753 + glutamate permease similar to GB:L10328 SP:P19933 GB:D00626 GB:X17499 PID:216541 gene gene1550 http://www.ncbi.nlm.nih.gov/gene/?term=HI1530 HI1531 HI1531 rimK rimK 1603792 1604700 - ribosomal protein S6 modification protein similar to SP:P17116 GB:X15859 PID:42747 GB:U00096 PID:1651386 gene gene1551 http://www.ncbi.nlm.nih.gov/gene/?term=HI1531 HI1532 HI1532 grxA grxA 1604817 1605080 + glutaredoxin functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase%3B also involved in reducing some disulfides in a coupled system with glutathione reductase gene gene1552 http://www.ncbi.nlm.nih.gov/gene/?term=HI1532 HI1533 HI1533 fabB fabB 1605147 1606367 - 3-oxoacyl-ACP synthase I FabB%2C beta-Ketoacyl-ACP synthase I%2C KASI%3B catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP%3B required for the elongation of short-chain unsaturated acyl-ACP gene gene1553 http://www.ncbi.nlm.nih.gov/gene/?term=HI1533 HI1534 HI1534 HI1534 1606516 1608528 + gene gene1554 http://www.ncbi.nlm.nih.gov/gene/?term=HI1534 HI1537 HI1537 licA licA 1608780 1609583 + LPS epitope variation mediator LicA similar to GB:M27280 SP:P14181 GB:M37912 PID:1574379 gene gene1555 http://www.ncbi.nlm.nih.gov/gene/?term=HI1537 HI1538 HI1538 licB licB 1609583 1610461 + lic-1 operon protein similar to GB:M27280 SP:P14182 gene gene1556 http://www.ncbi.nlm.nih.gov/gene/?term=HI1538 HI1539 HI1539 licC licC 1610458 1611159 + lic-1 operon protein similar to GB:M27280 SP:P14183 gene gene1557 http://www.ncbi.nlm.nih.gov/gene/?term=HI1539 HI1540 HI1540 licD licD 1611159 1611956 + lic-1 operon protein similar to GB:M27280 SP:P14184 gene gene1558 http://www.ncbi.nlm.nih.gov/gene/?term=HI1540 HI1541 HI1541 sppA sppA 1611994 1613841 - protease IV similar to GB:M13359 SP:P08395 GB:U13772 GB:U13773 GB:U13774 gene gene1559 http://www.ncbi.nlm.nih.gov/gene/?term=HI1541 HI1542 HI1542 HI1542 1613939 1614493 + hypothetical protein similar to PID:2253239 gene gene1560 http://www.ncbi.nlm.nih.gov/gene/?term=HI1542 HI1543 HI1543 HI1543 1614541 1615095 - anaerobic dehydrogenase subunit similar to GB:U00096 SP:P75915 PID:1787272 gene gene1561 http://www.ncbi.nlm.nih.gov/gene/?term=HI1543 HI1544 HI1544 HI1544 1615095 1615703 - NAD(P)H oxidoreductase similar to SP:Q64669 PID:595518 gene gene1562 http://www.ncbi.nlm.nih.gov/gene/?term=HI1544 HI1545 HI1545 HI1545 1615824 1617068 - serine/threonine transporter SstT involved in the import of serine and threonine coupled with the import of sodium gene gene1563 http://www.ncbi.nlm.nih.gov/gene/?term=HI1545 HI1546 HI1546 HI1546 1617353 1617775 + hypothetical protein gene gene1564 http://www.ncbi.nlm.nih.gov/gene/?term=HI1546 HI1547 HI1547 aroG aroG 1617864 1618952 - phospho-2-dehydro-3-deoxyheptonate aldolase catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate%2C phenylalanine sensitive gene gene1565 http://www.ncbi.nlm.nih.gov/gene/?term=HI1547 HI1548 HI1548 HI1548 1619170 1620420 - outer membrane-specific lipoprotein transporter subunit LolE part of the ATP-dependent transport system LolCDE%3B responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane gene gene1566 http://www.ncbi.nlm.nih.gov/gene/?term=HI1548 HI1549 HI1549 HI1549 1620420 1621103 - ABC transporter ATP-binding protein similar to GB:U00096 SP:P75957 PID:1787361 gene gene1567 http://www.ncbi.nlm.nih.gov/gene/?term=HI1549 HI1550 HI1550 bioD bioD 1621250 1621825 - dithiobiotin synthetase DTB synthetase%3B dethiobiotin synthase%3B involved in production of dethiobiotin from ATP and 7%2C8-diaminononanoate and carbon dioxide%3B contains magnesium gene gene1568 http://www.ncbi.nlm.nih.gov/gene/?term=HI1550 HI1551 HI1551 HI1551 1621835 1622617 - biotin synthase similar to GB:J04423 SP:P12999 PID:145427 PID:490221 GB:U00096 gene gene1569 http://www.ncbi.nlm.nih.gov/gene/?term=HI1551 HI1552 HI1552 HI1552 1622605 1623252 - hypothetical protein gene gene1570 http://www.ncbi.nlm.nih.gov/gene/?term=HI1552 HI1553 HI1553 bioF bioF 1623262 1624404 - 8-amino-7-oxononanoate synthase catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine gene gene1571 http://www.ncbi.nlm.nih.gov/gene/?term=HI1553 HI1554 HI1554 bioA bioA 1624413 1625705 - adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7%2C8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate gene gene1572 http://www.ncbi.nlm.nih.gov/gene/?term=HI1554 HI1555 HI1555 HI1555 1625724 1626905 - hypothetical protein similar to GB:U00096 SP:P75956 PID:1787360 gene gene1573 http://www.ncbi.nlm.nih.gov/gene/?term=HI1555 HI1556 HI1556 HI1556 1626905 1627852 - glycerate dehydrogenase Catalyzes the reduction of hydroxypyruvate to form D-glycerate%2C using NADH as an electron donor gene gene1574 http://www.ncbi.nlm.nih.gov/gene/?term=HI1556 HI1557 HI1557 kdsA kdsA 1627912 1628766 - 2-dehydro-3-deoxyphosphooctonate aldolase catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis gene gene1575 http://www.ncbi.nlm.nih.gov/gene/?term=HI1557 HI1558 HI1558 HI1558 1628781 1629584 - hypothetical protein similar to SP:P20101 GB:X05552 PID:41872 PID:1008040 GB:U00096 gene gene1576 http://www.ncbi.nlm.nih.gov/gene/?term=HI1558 HI1559 HI1559 hemK hemK 1629584 1630462 - hypothetical protein similar to GB:D28567 SP:P37186 PID:466533 PID:968931 GB:U00096 gene gene1577 http://www.ncbi.nlm.nih.gov/gene/?term=HI1559 HI1560 HI1560 HI1560 1630462 1630932 - hypothetical protein gene gene1578 http://www.ncbi.nlm.nih.gov/gene/?term=HI1560 HI1561 HI1561 prfA prfA 1630955 1632040 - peptide chain release factor 1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1%3B this protein is similar to release factor 2 gene gene1579 http://www.ncbi.nlm.nih.gov/gene/?term=HI1561 HI1563 HI1563 HI1563 1632558 1633094 - hypothetical protein similar to GB:U00096 PID:1788666 gene gene1580 http://www.ncbi.nlm.nih.gov/gene/?term=HI1563 HI1564 HI1564 HI1564 1633127 1633279 - hypothetical protein gene gene1581 http://www.ncbi.nlm.nih.gov/gene/?term=HI1564 HI1565m HI1565m HI1565m 1633785 1636722 + gene gene1582 http://www.ncbi.nlm.nih.gov/gene/?term=HI1565m HI1568 HI1568 HI1568 1636791 1637207 - Mu-like prophage FluMu G protein similar to bacteriophage Mu G-2 protein%3B SP:Q01261 PID:215535 gene gene1583 http://www.ncbi.nlm.nih.gov/gene/?term=HI1568 HI1570 HI1570 HI1570 1637331 1638037 - gene gene1584 http://www.ncbi.nlm.nih.gov/gene/?term=HI1570 HI1571 HI1571 HI1571 1638049 1638288 - hypothetical protein gene gene1585 http://www.ncbi.nlm.nih.gov/gene/?term=HI1571 HI1571.1 HI1571.1 HI1571.1 1638282 1638823 + gene gene1586 http://www.ncbi.nlm.nih.gov/gene/?term=HI1571.1 HI1572 HI1572 HI1572 1638626 1639726 - gene gene1587 http://www.ncbi.nlm.nih.gov/gene/?term=HI1572 HI1572.1 HI1572.1 HI1572.1 1639927 1640003 - tRNA-Val tRNA gene1588 http://www.ncbi.nlm.nih.gov/gene/?term=HI1572.1 HI1573 HI1573 pykA pykA 1640232 1641668 + pyruvate kinase catalyzes the formation of phosphoenolpyruvate from pyruvate gene gene1589 http://www.ncbi.nlm.nih.gov/gene/?term=HI1573 HI1574 HI1574 dnaB dnaB 1641702 1643216 + replicative DNA helicase unwinds double stranded DNA gene gene1590 http://www.ncbi.nlm.nih.gov/gene/?term=HI1574 HI1575 HI1575 alr alr 1643226 1644308 + alanine racemase converts L-alanine to D-alanine which is used in cell wall biosynthesis%3B binds one pyridoxal phosphate per monomer%3B forms a homodimer gene gene1591 http://www.ncbi.nlm.nih.gov/gene/?term=HI1575 HI1576 HI1576 pgi pgi 1644405 1646054 + glucose-6-phosphate isomerase functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis%3B catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate%3B member of PGI family gene gene1592 http://www.ncbi.nlm.nih.gov/gene/?term=HI1576 HI1577 HI1577 HI1577 1646128 1646387 + gene gene1593 http://www.ncbi.nlm.nih.gov/gene/?term=HI1577 HI1578 HI1578 HI1578 1646702 1647673 + glycosyl transferase similar to PID:595813 gene gene1594 http://www.ncbi.nlm.nih.gov/gene/?term=HI1578 HI1579 HI1579 lpp lpp 1647856 1648323 - 15 kDa peptidoglycan-associated lipoprotein similar to GB:M18877 SP:P10325 gene gene1595 http://www.ncbi.nlm.nih.gov/gene/?term=HI1579 HI1581 HI1581 HI1581 1648637 1649217 - gene gene1596 http://www.ncbi.nlm.nih.gov/gene/?term=HI1581 HI1583 HI1583 argS argS 1649297 1651030 + arginine--tRNA ligase catalyzes a two-step reaction%2C first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B class-I aminoacyl-tRNA synthetase gene gene1597 http://www.ncbi.nlm.nih.gov/gene/?term=HI1583 HI1584 HI1584 ilvH ilvH 1651323 1651814 - acetolactate synthase small subunit with IlvI catalyzes the formation of 2-acetolactate from pyruvate%2C the small subunit is required for full activity and valine sensitivity%3B E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates%2C valine sensitivity and affinity for cofactors%3B also known as acetolactate synthase 3 small subunit gene gene1598 http://www.ncbi.nlm.nih.gov/gene/?term=HI1584 HI1585 HI1585 ilvI ilvI 1651814 1653535 - acetolactate synthase large subunit acetolactate synthase large subunit%3B catalyzes the formation of 2-acetolactate from pyruvate gene gene1599 http://www.ncbi.nlm.nih.gov/gene/?term=HI1585 HI1586 HI1586 HI1586 1653802 1655361 - hypothetical protein similar to GB:AE000511 PID:2314087 gene gene1600 http://www.ncbi.nlm.nih.gov/gene/?term=HI1586 HI1587 HI1587 hns hns 1655765 1656169 + DNA-binding protein H-NS similar to GB:X07688 SP:P08936 GB:X57231 GB:X59940 GB:X67326 gene gene1601 http://www.ncbi.nlm.nih.gov/gene/?term=HI1587 HI1588 HI1588 purU purU 1656239 1657075 + formyltetrahydrofolate deformylase produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis%3B has a role in one-carbon metabolism%3B forms a homohexamer%3B activated by methionine and inhibited by glycine gene gene1602 http://www.ncbi.nlm.nih.gov/gene/?term=HI1588 HI1589 HI1589 aroA aroA 1657075 1658373 + 3-phosphoshikimate 1-carboxyvinyltransferase catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis gene gene1603 http://www.ncbi.nlm.nih.gov/gene/?term=HI1589 HI1590 HI1590 HI1590 1658455 1659795 - recombination factor protein RarA similar to SP:P45526 GB:U00096 PID:1787119 gene gene1604 http://www.ncbi.nlm.nih.gov/gene/?term=HI1590 HI1591 HI1591 lolA lolA 1659856 1660473 - outer-membrane lipoprotein carrier protein participates with LolB in the incorporation of lipoprotein into the outer membrane gene gene1605 http://www.ncbi.nlm.nih.gov/gene/?term=HI1591 HI1595m HI1595m ftsK ftsK 1660491 1663260 - gene gene1606 http://www.ncbi.nlm.nih.gov/gene/?term=HI1595m HI1596 HI1596 lrp lrp 1663262 1663741 - leucine-responsive transcriptional regulator mediates a global response to leucine%3B acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system gene gene1607 http://www.ncbi.nlm.nih.gov/gene/?term=HI1596 HI1597 HI1597 radA radA 1663821 1665197 - DNA repair protein RadA Sms%3B stabilizes the strand-invasion intermediate during the DNA repair%3B involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents gene gene1608 http://www.ncbi.nlm.nih.gov/gene/?term=HI1597 HI1598 HI1598 HI1598 1665333 1666391 - hypothetical protein similar to SP:P30871 GB:Z21844 PID:49399 GB:U00096 PID:1789434 gene gene1609 http://www.ncbi.nlm.nih.gov/gene/?term=HI1598 HI1599 HI1599 HI1599 1666703 1667401 - hypothetical protein gene gene1610 http://www.ncbi.nlm.nih.gov/gene/?term=HI1599 HI1600 HI1600 HI1600 1667409 1668362 - hypothetical protein gene gene1611 http://www.ncbi.nlm.nih.gov/gene/?term=HI1600 HI1601 HI1601 HI1601 1668392 1668679 - hypothetical protein gene gene1612 http://www.ncbi.nlm.nih.gov/gene/?term=HI1601 HI1602 HI1602 HI1602 1668718 1669158 - hypothetical protein gene gene1613 http://www.ncbi.nlm.nih.gov/gene/?term=HI1602 HI1603 HI1603 HI1603 1669381 1670061 + phosphate transport regulator similar to GB:AE000782 gene gene1614 http://www.ncbi.nlm.nih.gov/gene/?term=HI1603 HI1604 HI1604 HI1604 1670086 1671348 + phosphate permease similar to PID:1814405 gene gene1615 http://www.ncbi.nlm.nih.gov/gene/?term=HI1604 HI1605 HI1605 HI1605 1671414 1672025 + hypothetical protein similar to SP:P39202 PID:1203798 GB:U00096 PID:1789435 gene gene1616 http://www.ncbi.nlm.nih.gov/gene/?term=HI1605 HI1606 HI1606 cca cca 1672032 1673282 + multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template%3B phosphohydrolase activities include hydrolysis of pyrophosphate%2C 5'-nucleoside tri- and diphosphates%2C NADP%2C and 2'-AMP with the production of Pi%2C metal-dependent phosphodiesterase activity for 2'%2C3'-cAMP%2C 2'%2C3'-cGMP%2C and 2'%2C3'-cCMP%2C and hydrolysis 2'%2C3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides%3B these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases gene gene1617 http://www.ncbi.nlm.nih.gov/gene/?term=HI1606 HI1607 HI1607 lolB lolB 1673345 1673974 + outer membrane lipoprotein LolB Incorporates lipoproteins in the outer membrane after they are released by the LolA protein gene gene1618 http://www.ncbi.nlm.nih.gov/gene/?term=HI1607 HI1608 HI1608 ipk ipk 1673986 1674927 + 4-diphosphocytidyl-2C-methyl-D-erythritol kinase An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis gene gene1619 http://www.ncbi.nlm.nih.gov/gene/?term=HI1608 HI1609 HI1609 prsA prsA 1674929 1675876 + ribose-phosphate pyrophosphokinase catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP gene gene1620 http://www.ncbi.nlm.nih.gov/gene/?term=HI1609 HI1610 HI1610 tyrS tyrS 1675940 1677145 - tyrosine--tRNA ligase catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) gene gene1621 http://www.ncbi.nlm.nih.gov/gene/?term=HI1610 HI1611 HI1611 sfsA sfsA 1677346 1678062 - sugar fermentation stimulation protein A Regulatory factor involved in maltose metabolism gene gene1622 http://www.ncbi.nlm.nih.gov/gene/?term=HI1611 HI1612 HI1612 HI1612 1678071 1679465 - multidrug efflux protein NorM%3B MdtK%3B functions as a Na(+)/drug antiporter%3B inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones gene gene1623 http://www.ncbi.nlm.nih.gov/gene/?term=HI1612 HI1613 HI1613 ribE ribE 1679509 1680123 + riboflavin synthase subunit alpha catalyzes the formation of riboflavin from 6%2C7-dimethyl-8-(1-D-ribityl)lumazine gene gene1624 http://www.ncbi.nlm.nih.gov/gene/?term=HI1613 HI1614 HI1614 pepN pepN 1680195 1682804 - aminopeptidase N similar to GB:M15273 SP:P04825 GB:M15676 GB:X04020 PID:147142 gene gene1625 http://www.ncbi.nlm.nih.gov/gene/?term=HI1614 HI1615 HI1615 purE purE 1682965 1683459 + 5-(carboxyamino)imidazole ribonucleotide mutase Catalyzes a step in the de novo purine nucleotide biosynthetic pathway gene gene1626 http://www.ncbi.nlm.nih.gov/gene/?term=HI1615 HI1616 HI1616 purK purK 1683529 1684617 + 5-(carboxyamino)imidazole ribonucleotide synthase With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway gene gene1627 http://www.ncbi.nlm.nih.gov/gene/?term=HI1616 HI1617 HI1617 aspC aspC 1684756 1685946 + aromatic amino acid aminotransferase catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate gene gene1628 http://www.ncbi.nlm.nih.gov/gene/?term=HI1617 HI1617.1 HI1617.1 HI1617.1 1686035 1686142 - gene gene1629 http://www.ncbi.nlm.nih.gov/gene/?term=HI1617.1 HI1618 HI1618 HI1618 1686173 1686790 - ABC transporter ATP-binding protein similar to GB:AE000666 gene gene1630 http://www.ncbi.nlm.nih.gov/gene/?term=HI1618 HI1619 HI1619 HI1619 1686792 1687425 - gene gene1631 http://www.ncbi.nlm.nih.gov/gene/?term=HI1619 HI1621 HI1621 HI1621 1687425 1688045 - cobalt transport protein CbiM catalyzes the ATP-dependent transport of cobalt gene gene1632 http://www.ncbi.nlm.nih.gov/gene/?term=HI1621 HI1622 HI1622 HI1622 1688045 1688530 - hypothetical protein gene gene1633 http://www.ncbi.nlm.nih.gov/gene/?term=HI1622 HI1623 HI1623 merR2 merR2 1689316 1689723 + mercuric resistance operon regulatory protein similar to GB:X57326 PID:48151 gene gene1635 http://www.ncbi.nlm.nih.gov/gene/?term=HI1623 HI1624 HI1624 HI1624 1688543 1689226 - branched-chain amino acid ABC transporter substrate-binding protein gene gene1634 http://www.ncbi.nlm.nih.gov/gene/?term=HI1624 HI1625 HI1625 HI1625 1689783 1690280 - hypothetical protein gene gene1636 http://www.ncbi.nlm.nih.gov/gene/?term=HI1625 HI1626 HI1626 HI1626 1690281 1690997 - hypothetical protein similar to SP:P46909 PID:971339 GB:AL009126 gene gene1637 http://www.ncbi.nlm.nih.gov/gene/?term=HI1626 HI1627 HI1627 HI1627 1691109 1691459 + hypothetical protein similar to PID:2407234 gene gene1638 http://www.ncbi.nlm.nih.gov/gene/?term=HI1627 HI1628 HI1628 HI1628 1691490 1691894 + hypothetical protein similar to SP:P39436 PID:606172 GB:U00096 PID:1789628 gene gene1639 http://www.ncbi.nlm.nih.gov/gene/?term=HI1628 HI1629 HI1629 HI1629 1691957 1692544 - hypothetical protein similar to GB:M68934 SP:P09548 GB:X02743 PID:146363 GB:U00096 gene gene1640 http://www.ncbi.nlm.nih.gov/gene/?term=HI1629 HI1630 HI1630 rpL25 rpL25 1692762 1693049 + 50S ribosomal protein L25 the Ctc family of proteins consists of two types%2C one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response gene gene1641 http://www.ncbi.nlm.nih.gov/gene/?term=HI1630 HI1631 HI1631 HI1631 1693148 1693720 - hypothetical protein gene gene1642 http://www.ncbi.nlm.nih.gov/gene/?term=HI1631 HI1631.1 HI1631.1 HI1631.1 1694187 1694263 - tRNA-Met tRNA gene1646 http://www.ncbi.nlm.nih.gov/gene/?term=HI1631.1 HI1631.2 HI1631.2 HI1631.2 1694097 1694181 - tRNA-Leu tRNA gene1645 http://www.ncbi.nlm.nih.gov/gene/?term=HI1631.2 HI1631.3 HI1631.3 HI1631.3 1693994 1694068 - tRNA-Gln tRNA gene1644 http://www.ncbi.nlm.nih.gov/gene/?term=HI1631.3 HI1631.4 HI1631.4 HI1631.4 1693872 1693946 - tRNA-Gln tRNA gene1643 http://www.ncbi.nlm.nih.gov/gene/?term=HI1631.4 HI1632 HI1632 HI1632 1694577 1694942 + hypothetical protein gene gene1647 http://www.ncbi.nlm.nih.gov/gene/?term=HI1632 HI1633 HI1633 purA purA 1695071 1696369 + adenylosuccinate synthetase catalyzes the formation of N6-(1%2C2%2C-dicarboxyethyl)-AMP from L-aspartate%2C inosine monophosphate and GTP in AMP biosynthesis gene gene1648 http://www.ncbi.nlm.nih.gov/gene/?term=HI1633 HI1634 HI1634 dapD dapD 1696426 1697253 - 2%2C3%2C4%2C5-tetrahydropyridine-2%2C6-dicarboxylate N-succinyltransferase catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway gene gene1649 http://www.ncbi.nlm.nih.gov/gene/?term=HI1634 HI1635 HI1635 purR purR 1697612 1698622 + DNA-binding transcriptional repressor PurR binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis%3B is involved in regulation of purB%2C purC%2C purEK%2C purHD%2C purL%2C purMN and guaBA expression%3B binds hypoxanthine and guanine as inducers gene gene1650 http://www.ncbi.nlm.nih.gov/gene/?term=HI1635 HI1636 HI1636 ppc ppc 1698805 1701444 + phosphoenolpyruvate carboxylase catalyzes the formation of oxaloacetate from phosphoenolpyruvate gene gene1651 http://www.ncbi.nlm.nih.gov/gene/?term=HI1636 HI1637 HI1637 HI1637 1701481 1702893 - hypothetical protein similar to GB:U00096 PID:1787581 gene gene1652 http://www.ncbi.nlm.nih.gov/gene/?term=HI1637 HI1638 HI1638 sapA sapA 1702963 1704660 + anti peptide resistance ABC transporter substrate-binding protein similar to SP:P36634 GB:X52093 GB:X74212 PID:414208 gene gene1653 http://www.ncbi.nlm.nih.gov/gene/?term=HI1638 HI1639 HI1639 sapB sapB 1704660 1705625 + peptide ABC transporter permease similar to SP:P36668 GB:X52093 GB:X74212 PID:414209 gene gene1654 http://www.ncbi.nlm.nih.gov/gene/?term=HI1639 HI1640 HI1640 sapC sapC 1705615 1706502 + peptide ABC transporter permease similar to SP:P36669 GB:X74212 PID:414210 gene gene1655 http://www.ncbi.nlm.nih.gov/gene/?term=HI1640 HI1641 HI1641 sapD sapD 1706506 1707555 + peptide ABC transporter ATP-binding protein similar to SP:P36636 GB:X74212 PID:414211 gene gene1656 http://www.ncbi.nlm.nih.gov/gene/?term=HI1641 HI1642 HI1642 sapF sapF 1707555 1708364 + anti peptide resistance ABC transporter ATP-binding protein similar to SP:P36637 GB:U08190 PID:470683 GB:U00096 PID:1279404 gene gene1657 http://www.ncbi.nlm.nih.gov/gene/?term=HI1642 HI1643 HI1643 HI1643 1708376 1709392 + hypothetical protein similar to SP:P33019 PID:405879 GB:U00096 PID:1788482 gene gene1658 http://www.ncbi.nlm.nih.gov/gene/?term=HI1643 HI1644 HI1644 truA truA 1709484 1710293 - tRNA pseudouridine synthase A mediates pseudouridylation (positions 38%2C 39%2C 40) at the tRNA anticodon region which contributes to the structural stability gene gene1659 http://www.ncbi.nlm.nih.gov/gene/?term=HI1644 HI1645 HI1645 fbp fbp 1710527 1711528 + fructose-1%2C6-bisphosphatase catalyzes the formation of D-fructose 6-phosphate from fructose-1%2C6-bisphosphate gene gene1660 http://www.ncbi.nlm.nih.gov/gene/?term=HI1645 HI1646m HI1646m cmk cmk 1711447 1712115 - cytidylate kinase Catalyzes the formation of (d)CDP from ATP and (d)CMP gene gene1661 http://www.ncbi.nlm.nih.gov/gene/?term=HI1646m HI1647 HI1647 HI1647 1712590 1713465 + pyridoxal biosynthesis lyase PdxS with PdxT forms pyridoxal 5'-phosphate from glutamine%2C either ribose 5-phosphate or ribulose 5-phosphate%2C and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate gene gene1662 http://www.ncbi.nlm.nih.gov/gene/?term=HI1647 HI1648 HI1648 HI1648 1713466 1714044 + glutamine amidotransferase subunit PdxT with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate%3B PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia%3B PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate gene gene1663 http://www.ncbi.nlm.nih.gov/gene/?term=HI1648 HI1649 HI1649 dld dld 1714592 1716286 - D-lactate dehydrogenase component of the membrane-bound D-lactate oxidase%2C FAD-binding%2C NADH independent gene gene1664 http://www.ncbi.nlm.nih.gov/gene/?term=HI1649 HI1650 HI1650 HI1650 1716547 1716657 + hypothetical protein gene gene1665 http://www.ncbi.nlm.nih.gov/gene/?term=HI1650 HI1651 HI1651 HI1651 1716772 1717050 - hypothetical protein nucleotide sequence similar to HI0220 gene gene1666 http://www.ncbi.nlm.nih.gov/gene/?term=HI1651 HI1652 HI1652 spr spr 1717801 1718352 - lipoprotein similar to GB:U00096 SP:P77685 PID:1498150 PID:1736840 PID:1788501 gene gene1667 http://www.ncbi.nlm.nih.gov/gene/?term=HI1652 HI1653 HI1653 tldD tldD 1718465 1719912 - hypothetical protein similar to Zn-dependent protease%3B this region contains an authentic frame shift and is not the result of a sequencing artifact%3B similar to SP:P46473 PID:606183 GB:U00096 PID:1732437 PID:1789640 gene gene1668 http://www.ncbi.nlm.nih.gov/gene/?term=HI1653 HI1654 HI1654 HI1654 1720014 1720865 - hypothetical protein similar to SP:P45528 PID:606086 GB:U00096 PID:1789535 gene gene1669 http://www.ncbi.nlm.nih.gov/gene/?term=HI1654 HI1655 HI1655 HI1655 1720937 1722664 + antigen similar to PID:1353671 gene gene1670 http://www.ncbi.nlm.nih.gov/gene/?term=HI1655 HI1656 HI1656 HI1656 1722664 1723023 + hypothetical protein similar to SP:P45465 PID:606088 GB:U00096 PID:1789538 gene gene1671 http://www.ncbi.nlm.nih.gov/gene/?term=HI1656 HI1657 HI1657 HI1657 1723036 1723620 + hypothetical protein similar to SP:P45466 PID:606089 GB:U00096 PID:1789539 gene gene1672 http://www.ncbi.nlm.nih.gov/gene/?term=HI1657 HI1658 HI1658 HI1658 1723677 1724258 + hypothetical protein similar to SP:P45467 PID:606090 GB:U00096 PID:1789540 gene gene1673 http://www.ncbi.nlm.nih.gov/gene/?term=HI1658 HI1659 HI1659 nrdA nrdA 1724513 1726783 + ribonucleotide-diphosphate reductase subunit alpha Catalyzes the rate-limiting step in dNTP synthesis gene gene1674 http://www.ncbi.nlm.nih.gov/gene/?term=HI1659 HI1660 HI1660 nrdB nrdB 1726925 1728055 + ribonucleotide-diphosphate reductase subunit beta B2 or R2 protein%3B type 1a enzyme%3B catalyzes the rate-limiting step in dNTP synthesis%3B converts nucleotides to deoxynucleotides%3B forms a homodimer and then a multimeric complex with NrdA gene gene1675 http://www.ncbi.nlm.nih.gov/gene/?term=HI1660 HI1661 HI1661 sucB sucB 1728171 1729400 - 2-oxoglutarate dehydrogenase E2 component dihydrolipoamide succinyltransferase similar to GB:J01619 SP:P07016 GB:X00664 PID:146202 PID:43022 gene gene1676 http://www.ncbi.nlm.nih.gov/gene/?term=HI1661 HI1662 HI1662 sucA sucA 1729503 1732310 - 2-oxoglutarate dehydrogenase subunit E1 SucA%3B E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate%3B SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide gene gene1677 http://www.ncbi.nlm.nih.gov/gene/?term=HI1662 HI1663 HI1663 HI1663 1732513 1733151 - hypothetical protein similar to GB:U00096 SP:P75849 PID:1787158 gene gene1678 http://www.ncbi.nlm.nih.gov/gene/?term=HI1663 HI1664 HI1664 HI1664 1733161 1733916 - hypothetical protein similar to GB:U00089 SP:P78005 PID:1673805 gene gene1679 http://www.ncbi.nlm.nih.gov/gene/?term=HI1664 HI1666 HI1666 HI1666 1733968 1734527 - gene gene1680 http://www.ncbi.nlm.nih.gov/gene/?term=HI1666 HI1667 HI1667 HI1667 1734543 1736012 - hypothetical protein similar to SP:P22525 GB:X57550 PID:42044 GB:U00096 PID:1787155 gene gene1681 http://www.ncbi.nlm.nih.gov/gene/?term=HI1667 HI1668 HI1668 prc prc 1736086 1738173 - carboxy-terminal protease Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 gene gene1682 http://www.ncbi.nlm.nih.gov/gene/?term=HI1668 HI1670 HI1670 HI1670 1738359 1738832 - solute/DNA competence effector affects solute and DNA transport through an unknown mechanism gene gene1683 http://www.ncbi.nlm.nih.gov/gene/?term=HI1670 HI1671 HI1671 HI1671 1739016 1740266 + hypothetical protein similar to GB:U00096 PID:1736474 PID:1736480 PID:1788137 gene gene1684 http://www.ncbi.nlm.nih.gov/gene/?term=HI1671 HI1672 HI1672 HI1672 1740250 1742895 + hypothetical protein similar to GB:U00096 PID:1736475 PID:1736481 PID:1788138 gene gene1685 http://www.ncbi.nlm.nih.gov/gene/?term=HI1672 HI1673 HI1673 moaE moaE 1742950 1743402 - molybdopterin converting factor subunit 2 similar to GB:X70420 SP:P30749 PID:42012 GB:U00096 PID:1787003 gene gene1686 http://www.ncbi.nlm.nih.gov/gene/?term=HI1673 HI1674 HI1674 moaD moaD 1743403 1743648 - molybdopterin synthase small subunit catalyzes the conversion of molybdopterin precursor Z into molybdopterin gene gene1687 http://www.ncbi.nlm.nih.gov/gene/?term=HI1674 HI1675 HI1675 moaC moaC 1743650 1744132 - molybdenum cofactor biosynthesis protein MoaC MoaC%3B along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z%3B involved in molybdenum cofactor biosynthesis gene gene1688 http://www.ncbi.nlm.nih.gov/gene/?term=HI1675 HI1676 HI1676 moaA moaA 1744224 1745237 - molybdenum cofactor biosynthesis protein A together with moaC%2C is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z gene gene1689 http://www.ncbi.nlm.nih.gov/gene/?term=HI1676 HI1677 HI1677 HI1677 1745682 1746353 + iron-sulfur cluster repair di-iron protein Involved in anaerobic NO protection and iron metabolism gene gene1690 http://www.ncbi.nlm.nih.gov/gene/?term=HI1677 HI1677.1 HI1677.1 HI1677.1 1746429 1746804 + gene gene1691 http://www.ncbi.nlm.nih.gov/gene/?term=HI1677.1 HI1678 HI1678 kpsF kpsF 1746890 1747903 + arabinose-5-phosphate isomerase KpsF similar to GB:L19929 SP:P42502 PID:455424 gene gene1692 http://www.ncbi.nlm.nih.gov/gene/?term=HI1678 HI1679 HI1679 yrbI yrbI 1747913 1748455 + 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC forms homotetramers%3B similar to SP:P45396 PID:606137 GB:U00096 PID:2367202 gene gene1693 http://www.ncbi.nlm.nih.gov/gene/?term=HI1679 HI1680 HI1680 HI1680 1748553 1750709 - hypothetical protein similar to GB:U00096 PID:1787194 gene gene1694 http://www.ncbi.nlm.nih.gov/gene/?term=HI1680 HI1681 HI1681 HI1681 1750777 1751442 - hypothetical protein similar to GB:U00096 PID:1787198 gene gene1695 http://www.ncbi.nlm.nih.gov/gene/?term=HI1681 HI1682 HI1682 sohB sohB 1751640 1752701 + protease SohB%3B periplasmic protein%3B member of the peptidase S49 family gene gene1696 http://www.ncbi.nlm.nih.gov/gene/?term=HI1682 HI1683 HI1683 HI1683 1752983 1753561 + Na(+)-translocating NADH-quinone reductase subunit E similar to rnfA/rnfE proteins%3B similar to GB:U00096 PID:1787914 gene gene1697 http://www.ncbi.nlm.nih.gov/gene/?term=HI1683 HI1684 HI1684 HI1684 1753649 1754230 + electron transport complex protein RnfB part of membrane-bound complex thought to be involved in electron transport to nitrogen gene gene1698 http://www.ncbi.nlm.nih.gov/gene/?term=HI1684 HI1685 HI1685 HI1685 1754231 1756690 + electron transport complex protein RnfC part of membrane-bound complex thought to be involved in electron transport to nitrogen gene gene1699 http://www.ncbi.nlm.nih.gov/gene/?term=HI1685 HI1686 HI1686 rnfD rnfD 1756695 1757771 + electron transport complex protein RnfD RnfD%3B RsxD%3B required for nitrogen fixation in Rhodobacter capsulatus%3B part of a membrane-bound complex thought to be involved in electron transport to nitrogenase%3B in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents gene gene1700 http://www.ncbi.nlm.nih.gov/gene/?term=HI1686 HI1687 HI1687 rnfG rnfG 1757771 1758394 + electron transport complex protein RnfG part of membrane-bound complex hought to be involved in electron transport to nitrogen gene gene1701 http://www.ncbi.nlm.nih.gov/gene/?term=HI1687 HI1688 HI1688 HI1688 1758396 1759103 + electron transport complex protein RsxE in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents%3B similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase gene gene1702 http://www.ncbi.nlm.nih.gov/gene/?term=HI1688 HI1689 HI1689 nth nth 1759288 1759923 + endonuclease III similar to GB:J02857 SP:P20625 PID:146972 GB:U00096 PID:1742691 gene gene1703 http://www.ncbi.nlm.nih.gov/gene/?term=HI1689 HI1690 HI1690 HI1690 1759981 1761354 + sodium-dependent transporter similar to GB:AL009126 gene gene1704 http://www.ncbi.nlm.nih.gov/gene/?term=HI1690 HI1691 HI1691 modC modC 1761378 1762433 - molybdate transporter ATP-binding protein Part of the ABC transporter complex modABC involved in molybdenum import gene gene1705 http://www.ncbi.nlm.nih.gov/gene/?term=HI1691 HI1692 HI1692 modB modB 1762420 1763109 - molybdate ABC transporter permease part of ModCBA molybdate transporter%3B member of ABC superfamily%3B inner membrane component%3B regulated by repressor protein ModE gene gene1706 http://www.ncbi.nlm.nih.gov/gene/?term=HI1692 HI1693 HI1693 modA modA 1763283 1764047 - molybdenum ABC transporter substrate-binding protein similar to GB:L34009 SP:P37329 PID:504498 PID:973214 PID:1147817 gene gene1707 http://www.ncbi.nlm.nih.gov/gene/?term=HI1693 HI1694 HI1694 modE modE 1764185 1764952 + molybdenum transport protein similar to PID:1002825 SP:P46930 GB:U00096 PID:1147816 PID:1786976 gene gene1708 http://www.ncbi.nlm.nih.gov/gene/?term=HI1694 HI1695 HI1695 HI1695 1765061 1765846 - UDP-galactose--lipooligosaccharide galactosyltransferase similar to PID:600434 SP:Q46635 gene gene1709 http://www.ncbi.nlm.nih.gov/gene/?term=HI1695 HI1696 HI1696 HI1696 1765866 1766750 - lipopolysaccharide biosynthesis protein similar to PID:1944156 gene gene1710 http://www.ncbi.nlm.nih.gov/gene/?term=HI1696 HI1697 HI1697 HI1697 1766762 1767535 - UDP-GlcNAc--lipooligosaccharide N-acetylglucosaminyl glycosyltransferase similar to GB:U05670 gene gene1711 http://www.ncbi.nlm.nih.gov/gene/?term=HI1697 HI1698 HI1698 HI1698 1767547 1768608 - lipopolysaccharide biosynthesis protein similar to PID:633695 gene gene1712 http://www.ncbi.nlm.nih.gov/gene/?term=HI1698 HI1699 HI1699 HI1699 1768610 1769524 - lipopolysaccharide biosynthesis protein similar to PID:1546004 gene gene1713 http://www.ncbi.nlm.nih.gov/gene/?term=HI1699 HI1700 HI1700 HI1700 1769521 1770726 - lipopolysaccharide biosynthesis protein similar to GB:AE000666 gene gene1714 http://www.ncbi.nlm.nih.gov/gene/?term=HI1700 HI1701 HI1701 HI1701 1770861 1771604 + hypothetical protein similar to PID:1652989 gene gene1715 http://www.ncbi.nlm.nih.gov/gene/?term=HI1701 HI1702 HI1702 metE metE 1771826 1774096 - 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine gene gene1716 http://www.ncbi.nlm.nih.gov/gene/?term=HI1702 HI1703 HI1703 HI1703 1774289 1775365 - hypothetical protein similar to GB:U14003 SP:P39341 PID:537104 GB:U00096 PID:1790713 gene gene1717 http://www.ncbi.nlm.nih.gov/gene/?term=HI1703 HI1704 HI1704 HI1704 1775349 1776467 - hypothetical protein similar to GB:U14003 SP:P39340 PID:537103 GB:U00096 PID:1790712 gene gene1718 http://www.ncbi.nlm.nih.gov/gene/?term=HI1704 HI1705 HI1705 pepA pepA 1776575 1778050 + leucyl aminopeptidase catalyzes the removal of N-terminal amino acids preferably leucine from various peptides gene gene1719 http://www.ncbi.nlm.nih.gov/gene/?term=HI1705 HI1706 HI1706 betT betT 1778086 1780029 - high affinity choline transport protein similar to SP:P17447 GB:X52905 PID:48716 GB:U00096 PID:1657512 gene gene1720 http://www.ncbi.nlm.nih.gov/gene/?term=HI1706 HI1707 HI1707 ygiY ygiY 1780390 1781745 - sensor protein QseC similar to SP:P40719 PID:882556 GB:U00096 PID:1789403 gene gene1721 http://www.ncbi.nlm.nih.gov/gene/?term=HI1707 HI1708 HI1708 ygiX ygiX 1781742 1782407 - transcriptional regulatory protein similar to PID:882555 SP:P52076 GB:U00096 PID:1789402 gene gene1722 http://www.ncbi.nlm.nih.gov/gene/?term=HI1708 HI1709 HI1709 HI1709 1782470 1782835 - hypothetical protein similar to PID:882554 SP:P52083 GB:U00096 PID:1789401 gene gene1723 http://www.ncbi.nlm.nih.gov/gene/?term=HI1709 HI1711 HI1711 crr crr 1783345 1783845 - PTS system glucose-specific transporter subunit functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system%3B functions in the transport and phosphorylation of glucose gene gene1724 http://www.ncbi.nlm.nih.gov/gene/?term=HI1711 HI1712 HI1712 ptsI ptsI 1783905 1785632 - phosphoenolpyruvate-protein phosphotransferase Phosphotransferase system%2C enzyme I%3B transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein%3B part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active-transport system gene gene1725 http://www.ncbi.nlm.nih.gov/gene/?term=HI1712 HI1713 HI1713 ptsH ptsH 1785712 1785969 - phosphocarrier protein HPr similar to SP:P07006 PID:153936 PID:47845 gene gene1726 http://www.ncbi.nlm.nih.gov/gene/?term=HI1713 HI1714 HI1714 HI1714 1786128 1787168 - ribosome-associated GTPase EngC%3B RsgA%3B CpgA%3B circularly permuted GTPase%3B ribosome small subunit-dependent GTPase A%3B has the pattern G4-G1-G3 as opposed to other GTPases%3B interacts strongly with 30S ribosome which stimulates GTPase activity gene gene1727 http://www.ncbi.nlm.nih.gov/gene/?term=HI1714 HI1715 HI1715 HI1715 1787239 1787787 + oligoribonuclease 3'-5' exoribonuclease specific for small oligoribonuclotides gene gene1728 http://www.ncbi.nlm.nih.gov/gene/?term=HI1715 HI1715.1 HI1715.1 HI1715.1 1787881 1787956 + tRNA-Gly tRNA gene1729 http://www.ncbi.nlm.nih.gov/gene/?term=HI1715.1 HI1716 HI1716 HI1716 1788088 1789155 - undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase rfe%3B similar to GB:M87049 SP:P24235 GB:M76129 PID:147578 PID:148187 gene gene1730 http://www.ncbi.nlm.nih.gov/gene/?term=HI1716 HI1718 HI1718 HI1718 1789352 1790369 - gene gene1731 http://www.ncbi.nlm.nih.gov/gene/?term=HI1718 HI1719 HI1719 glnD glnD 1790426 1793017 - PII uridylyl-transferase similar to GB:M96431 SP:P27249 PID:146155 PID:49393 PID:473822 gene gene1732 http://www.ncbi.nlm.nih.gov/gene/?term=HI1719 HI1720 HI1720 HI1720 1793136 1793645 + hypothetical protein similar to GB:U09558 PID:495495 gene gene1733 http://www.ncbi.nlm.nih.gov/gene/?term=HI1720 HI1721 HI1721 HI1721 1793696 1794463 + transposase similar to SP:P19769 GB:X07037 PID:581111 PID:912474 GB:U00096 gene gene1734 http://www.ncbi.nlm.nih.gov/gene/?term=HI1721 HI1722 HI1722 map map 1794526 1795332 - methionine aminopeptidase catalyzes the removal of N-terminal amino acids from peptides and arylamides%3B generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn%2C Fe%2C or Mn gene gene1735 http://www.ncbi.nlm.nih.gov/gene/?term=HI1722 HI1723 HI1723 HI1723 1795468 1795812 + iron-sulfur cluster insertion protein ErpA essential respiratory protein A%3B may be involved in the transfer of iron-sulfur clusters%3B essential for growth using oxygen or alternate electron acceptors gene gene1736 http://www.ncbi.nlm.nih.gov/gene/?term=HI1723 HI1724 HI1724 HI1724 1795814 1796167 + hypothetical protein similar to SP:P45567 GB:U00096 PID:1786310 gene gene1737 http://www.ncbi.nlm.nih.gov/gene/?term=HI1724 HI1725 HI1725 ponB ponB 1796174 1798519 + penicillin-binding protein 1B similar to GB:D26562 SP:P02919 GB:M12486 GB:X02163 PID:145948 gene gene1738 http://www.ncbi.nlm.nih.gov/gene/?term=HI1725 HI1726 HI1726 hemH hemH 1798692 1799564 + phosphoribosylaminoimidazole-succinocarboxamide synthase catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis%3B SAICAR synthase gene gene1739 http://www.ncbi.nlm.nih.gov/gene/?term=HI1726 HI1727 HI1727 argG argG 1799720 1801054 + argininosuccinate synthase catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis gene gene1740 http://www.ncbi.nlm.nih.gov/gene/?term=HI1727 HI1728 HI1728 HI1728 1801125 1802318 - hypothetical protein similar to SP:P42964 PID:707085 PID:1805475 GB:AL009126 gene gene1741 http://www.ncbi.nlm.nih.gov/gene/?term=HI1728 HI1729m HI1729m HI1729m 1802362 1803099 - LamB/YcsF family protein gene gene1742 http://www.ncbi.nlm.nih.gov/gene/?term=HI1729m HI1730 HI1730 HI1730 1803086 1804015 - hypothetical protein similar to GB:U00096 SP:P75745 PID:1786930 gene gene1743 http://www.ncbi.nlm.nih.gov/gene/?term=HI1730 HI1731 HI1731 HI1731 1804012 1804653 - hypothetical protein similar to GB:U00096 SP:P75744 PID:1786929 gene gene1744 http://www.ncbi.nlm.nih.gov/gene/?term=HI1731 HI1731a HI1731a HI1731a 1804886 1807948 - Hsf-like protein gene gene1745 http://www.ncbi.nlm.nih.gov/gene/?term=HI1731a HI1732 HI1732 HI1732 1807963 1808859 - gene gene1746 http://www.ncbi.nlm.nih.gov/gene/?term=HI1732 HI1733 HI1733 rnb rnb 1809215 1811194 - exoribonuclease II Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction gene gene1747 http://www.ncbi.nlm.nih.gov/gene/?term=HI1733 HI1734 HI1734 fabI fabI 1811277 1812065 - enoyl reductase acyl-carrier-protein reductase%3B similar to GB:M97219 SP:P29132 GB:X78733 PID:145851 PID:587106 gene gene1748 http://www.ncbi.nlm.nih.gov/gene/?term=HI1734 HI1735 HI1735 prfC prfC 1812244 1813827 + peptide chain release factor 3 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred%3B GDP/GTP-binding protein gene gene1749 http://www.ncbi.nlm.nih.gov/gene/?term=HI1735 HI1736 HI1736 HI1736 1813903 1814136 - hypothetical protein gene gene1750 http://www.ncbi.nlm.nih.gov/gene/?term=HI1736 HI1737 HI1737 HI1737 1814239 1814568 - branched-chain amino acid ABC transporter permease similar to GB:AL009126 gene gene1751 http://www.ncbi.nlm.nih.gov/gene/?term=HI1737 HI1738 HI1738 HI1738 1814565 1815299 - branched-chain amino acid ABC transporter permease similar to GB:AL009126 gene gene1752 http://www.ncbi.nlm.nih.gov/gene/?term=HI1738 HI1739 HI1739 metR metR 1815309 1816238 - transcriptional activator similar to GB:J04155 SP:P19797 GB:M37630 PID:1790262 gene gene1753 http://www.ncbi.nlm.nih.gov/gene/?term=HI1739 HI1739.1 HI1739.1 lldD lldD 1822366 1823511 - L-lactate dehydrogenase flavin mononucleotide-dependent dehydrogenase%3B functions in aerobic respiration and also has a role in anaerobic nitrate respiration gene gene1759 http://www.ncbi.nlm.nih.gov/gene/?term=HI1739.1 HI1739.2 HI1739.2 murI murI 1823723 1824532 - glutamate racemase converts L-glutamate to D-glutamate%2C a component of peptidoglycan gene gene1760 http://www.ncbi.nlm.nih.gov/gene/?term=HI1739.2 HI1739.3 HI1739.3 HIrrnD16S HIrrnD16S 1820456 1822004 - 16S ribosomal RNA rRNA gene1758 http://www.ncbi.nlm.nih.gov/gene/?term=HI1739.3 HI1739.4 HI1739.4 HI1739.4 1820304 1820380 - tRNA-Ile tRNA gene1757 http://www.ncbi.nlm.nih.gov/gene/?term=HI1739.4 HI1739.5 HI1739.5 HI1739.5 1820143 1820218 - tRNA-Ala tRNA gene1756 http://www.ncbi.nlm.nih.gov/gene/?term=HI1739.5 HI1739.6 HI1739.6 HIrrnD23S HIrrnD23S 1816839 1819741 - 23S ribosomal RNA rRNA gene1755 http://www.ncbi.nlm.nih.gov/gene/?term=HI1739.6 HI1739.7 HI1739.7 HIrrnD5S HIrrnD5S 1816484 1816598 - 5S ribosomal RNA rRNA gene1754 http://www.ncbi.nlm.nih.gov/gene/?term=HI1739.7 HI1740 HI1740 recG recG 1824562 1826643 - ATP-dependent DNA helicase RecG catalyzes branch migration in Holliday junction intermediates gene gene1761 http://www.ncbi.nlm.nih.gov/gene/?term=HI1740 HI1741 HI1741 spoT spoT 1826640 1828754 - guanosine-3'5'-bis(diphosphate) 3'- pyrophosphohydrolase similar to GB:L10328 SP:P17580 GB:M24503 PID:290500 PID:551840 gene gene1762 http://www.ncbi.nlm.nih.gov/gene/?term=HI1741 HI1742 HI1742 rpoZ rpoZ 1828934 1829200 - DNA-directed RNA polymerase subunit omega promotes RNA polymerase assembly or stability%3B latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits gene gene1763 http://www.ncbi.nlm.nih.gov/gene/?term=HI1742 HI1743 HI1743 gmk gmk 1829263 1829889 - guanylate kinase Essential for recycling GMP and indirectly%2C cGMP gene gene1764 http://www.ncbi.nlm.nih.gov/gene/?term=HI1743