locus-tag	class	description
INP94_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
INP94_RS00010	COG0592	DNA-directed DNA polymerase activity
INP94_RS00020	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
INP94_RS00025	COG0363	glucosamine-6-phosphate deaminase activity
INP94_RS00030	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
INP94_RS00035	COG1737	Transcriptional regulator
INP94_RS00045	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
INP94_RS00050	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
INP94_RS00050	COG1263	PTS System
INP94_RS00050	COG2190	(PTS) system
INP94_RS00055	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
INP94_RS00075	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
INP94_RS00085	COG0227	Belongs to the bacterial ribosomal protein bL28 family
INP94_RS00100	COG1811	Na channel or pump
INP94_RS00115	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
INP94_RS00120	COG0437	4 iron, 4 sulfur cluster binding
INP94_RS00125	COG3301	Polysulphide reductase, NrfD
INP94_RS00130	COG1138	Cytochrome C-type biogenesis protein
INP94_RS00135	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
INP94_RS00140	COG3088	subunit of a heme lyase
INP94_RS00140	COG4235	cytochrome complex assembly
INP94_RS00145	COG2081	HI0933 family
INP94_RS00150	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
INP94_RS00155	COG0477	Major facilitator Superfamily
INP94_RS00160	COG2267	carboxylic ester hydrolase activity
INP94_RS00170	COG1169	isochorismate synthase
INP94_RS00175	COG0436	Aminotransferase
INP94_RS00180	COG4589	Belongs to the CDS family
INP94_RS00190	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
INP94_RS00205	COG0681	Belongs to the peptidase S26 family
INP94_RS00210	COG0481	GTPase activity
INP94_RS00225	COG0590	tRNA wobble adenosine to inosine editing
INP94_RS00240	COG0730	response to heat
INP94_RS00250	COG3023	N-Acetylmuramoyl-L-alanine amidase
INP94_RS00255	COG4969	Belongs to the N-Me-Phe pilin family
INP94_RS00260	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
INP94_RS00265	COG1459	type II secretion system
INP94_RS00270	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
INP94_RS00275	COG0237	dephospho-CoA kinase activity
INP94_RS00290	COG0513	Belongs to the DEAD box helicase family
INP94_RS00295	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
INP94_RS00300	COG1792	Involved in formation and maintenance of cell shape
INP94_RS00305	COG1077	Cell shape determining protein MreB Mrl
INP94_RS00310	COG4178	(ABC) transporter
INP94_RS00320	COG0799	negative regulation of ribosome biogenesis
INP94_RS00330	COG0768	penicillin binding
INP94_RS00335	COG0772	Belongs to the SEDS family
INP94_RS00340	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
INP94_RS00340	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
INP94_RS00345	COG1686	Belongs to the peptidase S11 family
INP94_RS00375	COG2814	Major facilitator Superfamily
INP94_RS00380	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
INP94_RS00390	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
INP94_RS00395	COG2252	PERMEase
INP94_RS00400	COG0826	peptidase U32
INP94_RS00450	COG1518	maintenance of DNA repeat elements
INP94_RS00460	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
INP94_RS00465	COG0343	queuine tRNA-ribosyltransferase activity
INP94_RS00470	COG3945	hemerythrin HHE cation binding domain
INP94_RS00475	COG0425	Belongs to the sulfur carrier protein TusA family
INP94_RS00480	COG1862	Preprotein translocase
INP94_RS00485	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
INP94_RS00490	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
INP94_RS00495	COG0628	permease
INP94_RS00500	COG0347	Belongs to the P(II) protein family
INP94_RS00505	COG0521	Mo-molybdopterin cofactor biosynthetic process
INP94_RS00510	COG0542	response to heat
INP94_RS00515	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
INP94_RS00525	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
INP94_RS00530	COG0564	pseudouridine synthase activity
INP94_RS00535	COG1496	oxidoreductase activity
INP94_RS00550	COG1385	rRNA (uridine-N3-)-methyltransferase activity
INP94_RS00605	COG0151	Belongs to the GarS family
INP94_RS00610	COG0138	bifunctional purine biosynthesis protein purh
INP94_RS00615	COG2259	Doxx family
INP94_RS00620	COG4232	protein-disulfide reductase activity
INP94_RS00625	COG0745	RESPONSE REGULATOR receiver
INP94_RS00640	COG0257	Belongs to the bacterial ribosomal protein bL36 family
INP94_RS00645	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
INP94_RS00650	COG0697	spore germination
INP94_RS00665	COG0142	geranyltranstransferase activity
INP94_RS00670	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
INP94_RS00680	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
INP94_RS00680	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
INP94_RS00695	COG2391	methyltransferase activity
INP94_RS00700	COG0425	Belongs to the sulfur carrier protein TusA family
INP94_RS00705	COG2731	YhcH YjgK YiaL family protein
INP94_RS00715	COG4785	May be involved in cell division
INP94_RS00720	COG0513	Belongs to the DEAD box helicase family
INP94_RS00725	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
INP94_RS00745	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
INP94_RS00750	COG1115	amino acid carrier protein
INP94_RS00755	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
INP94_RS00765	COG0560	Phosphoserine phosphatase
INP94_RS00785	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
INP94_RS00810	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
INP94_RS00820	COG0805	protein transport
INP94_RS00835	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
INP94_RS00840	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
INP94_RS00860	COG2991	Protein conserved in bacteria
INP94_RS00865	COG1477	protein flavinylation
INP94_RS00875	COG2871	sodium ion transport
INP94_RS00880	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
INP94_RS00890	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
INP94_RS00905	COG0271	Belongs to the BolA IbaG family
INP94_RS00910	COG3056	Lipoprotein
INP94_RS00915	COG0598	Magnesium transport protein CorA
INP94_RS00920	COG0762	integral membrane protein
INP94_RS00925	COG1872	DUF167
INP94_RS00935	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
INP94_RS00940	COG1466	dna polymerase III delta subunit
INP94_RS00945	COG1368	sulfuric ester hydrolase activity
INP94_RS00950	COG0494	nUDIX hydrolase
INP94_RS00965	COG4701	Protein of unknown function (DUF721)
INP94_RS00970	COG0338	D12 class N6 adenine-specific DNA methyltransferase
INP94_RS00975	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
INP94_RS00990	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
INP94_RS01005	COG1131	(ABC) transporter
INP94_RS01010	COG0842	Transport permease protein
INP94_RS01105	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
INP94_RS01115	COG1028	Short-chain dehydrogenase reductase Sdr
INP94_RS01120	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
INP94_RS01125	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
INP94_RS01135	COG1028	Short-chain dehydrogenase reductase Sdr
INP94_RS01140	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
INP94_RS01160	COG1399	metal-binding, possibly nucleic acid-binding protein
INP94_RS01165	COG1132	(ABC) transporter
INP94_RS01170	COG4977	sequence-specific DNA binding
INP94_RS01170	COG1917	Cupin 2, conserved barrel domain protein
INP94_RS01175	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
INP94_RS01180	COG0859	PFAM glycosyl transferase family 9
INP94_RS01195	COG0475	glutathione-regulated potassium exporter activity
INP94_RS01195	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
INP94_RS01210	COG0751	glycine-tRNA ligase activity
INP94_RS01215	COG2852	Protein conserved in bacteria
INP94_RS01235	COG4545	Glutaredoxin-related protein
INP94_RS01250	COG4206	TonB-dependent receptor
INP94_RS01270	COG0105	UTP biosynthetic process
INP94_RS01280	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
INP94_RS01340	COG0174	glutamine synthetase
INP94_RS01345	COG1217	gtp-binding protein TYPA
INP94_RS01355	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
INP94_RS01360	COG2814	Major facilitator Superfamily
INP94_RS01365	COG4974	Belongs to the 'phage' integrase family
INP94_RS01370	COG1929	Belongs to the glycerate kinase type-1 family
INP94_RS01375	COG2610	gluconate transmembrane transporter activity
INP94_RS01380	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
INP94_RS01385	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
INP94_RS01390	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
INP94_RS01395	COG1381	Involved in DNA repair and RecF pathway recombination
INP94_RS01405	COG3266	domain, Protein
INP94_RS01405	COG3061	Opacity-associated protein A
INP94_RS01410	COG1509	lysine 2,3-aminomutase activity
INP94_RS01425	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
INP94_RS01430	COG1882	Formate acetyltransferase
INP94_RS01435	COG2116	formate transmembrane transporter activity
INP94_RS01440	COG1555	photosystem II stabilization
INP94_RS01450	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
INP94_RS01490	COG1216	Glycosyl transferase, family 2
INP94_RS01510	COG4316	Uncharacterized protein conserved in bacteria (DUF2251)
INP94_RS01515	COG1011	Hydrolase
INP94_RS01525	COG0754	glutathionylspermidine amidase activity
INP94_RS01530	COG1979	alcohol dehydrogenase
INP94_RS01545	COG0250	Participates in transcription elongation, termination and antitermination
INP94_RS01550	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
INP94_RS01555	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
INP94_RS01570	COG1652	LysM domain
INP94_RS01575	COG2321	neutral zinc metallopeptidase
INP94_RS01600	COG0196	riboflavin kinase activity
INP94_RS01605	COG0728	peptidoglycan biosynthetic process
INP94_RS01615	COG0557	exoribonuclease II activity
INP94_RS01620	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
INP94_RS01625	COG1114	Component of the transport system for branched-chain amino acids
INP94_RS01630	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
INP94_RS01635	COG1216	Glycosyl transferase, family 2
INP94_RS01650	COG1522	sequence-specific DNA binding
INP94_RS01655	COG2962	Rard protein
INP94_RS01660	COG1566	PFAM secretion protein HlyD family protein
INP94_RS01665	COG2814	Major facilitator Superfamily
INP94_RS01670	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
INP94_RS01675	COG0629	single-stranded DNA binding
INP94_RS01680	COG2132	Multicopper oxidase
INP94_RS01695	COG2116	formate transmembrane transporter activity
INP94_RS01735	COG0583	DNA-binding transcription factor activity
INP94_RS01740	COG2249	NAD(P)H dehydrogenase (quinone) activity
INP94_RS01750	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
INP94_RS01780	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
INP94_RS01780	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
INP94_RS01785	COG3715	PTS system
INP94_RS01790	COG3716	PTS system mannose fructose sorbose family IID component
INP94_RS01810	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
INP94_RS01815	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
INP94_RS01815	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
INP94_RS01825	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
INP94_RS01830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
INP94_RS01835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
INP94_RS01840	COG1120	ATPase activity
INP94_RS01850	COG1649	PFAM Uncharacterised BCR, COG1649
INP94_RS01850	COG0726	polysaccharide deacetylase
INP94_RS01855	COG1215	transferase activity, transferring glycosyl groups
INP94_RS01900	COG0859	PFAM glycosyl transferase family 9
INP94_RS01905	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
INP94_RS01910	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
INP94_RS01925	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
INP94_RS01940	COG0641	radical SAM
INP94_RS01945	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
INP94_RS01950	COG3119	arylsulfatase activity
INP94_RS01955	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
INP94_RS01960	COG0730	response to heat
INP94_RS01965	COG3956	TIGRFAM MazG family protein
INP94_RS02005	COG3070	regulator of competence-specific genes
INP94_RS02010	COG4667	esterase of the alpha-beta hydrolase superfamily
INP94_RS02030	COG0561	phosphatase activity
INP94_RS02050	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
INP94_RS02060	COG0038	chloride channel
INP94_RS02065	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
INP94_RS02075	COG3172	ATPase kinase involved in NAD metabolism
INP94_RS02080	COG2129	metallophosphoesterase
INP94_RS02100	COG0210	DNA helicase
INP94_RS02105	COG5645	(Lipo)protein
INP94_RS02115	COG1519	Transferase
INP94_RS02120	COG0463	Glycosyl transferase, family 2
INP94_RS02125	COG4783	chaperone-mediated protein folding
INP94_RS02135	COG2861	carbohydrate metabolic process
INP94_RS02140	COG4942	peptidase
INP94_RS02155	COG1187	pseudouridine synthase activity
INP94_RS02160	COG3468	outer membrane autotransporter barrel domain protein
INP94_RS02170	COG0583	DNA-binding transcription factor activity
INP94_RS02175	COG2962	Rard protein
INP94_RS02185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
INP94_RS02190	COG0488	(ABC) transporter
INP94_RS02195	COG0551	DNA topoisomerase type I activity
INP94_RS02205	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
INP94_RS02210	COG2818	Glycosylase
INP94_RS02220	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
INP94_RS02225	COG0456	acetyltransferase
INP94_RS02235	COG2197	response regulator
INP94_RS02240	COG3072	Adenylate cyclase
INP94_RS02245	COG0181	hydroxymethylbilane synthase activity
INP94_RS02255	COG2959	enzyme of heme biosynthesis
INP94_RS02260	COG3071	HemY protein
INP94_RS02265	COG0765	amino acid transport
INP94_RS02270	COG0765	amino acid transport
INP94_RS02280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
INP94_RS02285	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
INP94_RS02325	COG2168	tRNA wobble position uridine thiolation
INP94_RS02330	COG2923	Belongs to the DsrF TusC family
INP94_RS02335	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
INP94_RS02340	COG2964	Protein conserved in bacteria
INP94_RS02345	COG0545	Peptidyl-prolyl cis-trans isomerase
INP94_RS02355	COG3842	ATPase activity
INP94_RS02365	COG1176	ABC-type spermidine putrescine transport system, permease component I
INP94_RS02375	COG0471	metal ion transport
INP94_RS02380	COG2814	Major facilitator Superfamily
INP94_RS02385	COG2186	Transcriptional regulator
INP94_RS02390	COG0673	inositol 2-dehydrogenase activity
INP94_RS02395	COG0673	inositol 2-dehydrogenase activity
INP94_RS02405	COG0259	pyridoxamine-phosphate oxidase activity
INP94_RS02410	COG0747	negative chemotaxis
INP94_RS02415	COG2814	Major facilitator Superfamily
INP94_RS02420	COG1763	Mo-molybdopterin cofactor biosynthetic process
INP94_RS02425	COG3026	antisigma factor binding
INP94_RS02430	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
INP94_RS02435	COG1595	DNA-templated transcription, initiation
INP94_RS02445	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
INP94_RS02445	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
INP94_RS02445	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
INP94_RS02450	COG1105	Belongs to the carbohydrate kinase PfkB family
INP94_RS02455	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
INP94_RS02455	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
INP94_RS02465	COG1253	flavin adenine dinucleotide binding
INP94_RS02475	COG0084	hydrolase, TatD family'
INP94_RS02480	COG0470	DNA polymerase III
INP94_RS02485	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
INP94_RS02490	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
INP94_RS02495	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
INP94_RS02505	COG0587	DNA-directed DNA polymerase activity
INP94_RS02520	COG2195	Cleaves the N-terminal amino acid of tripeptides
INP94_RS02530	COG0746	molybdenum cofactor guanylyltransferase activity
INP94_RS02535	COG3084	Protein conserved in bacteria
INP94_RS02540	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
INP94_RS02545	COG3085	chromosome segregation
INP94_RS02560	COG3086	response to oxidative stress
INP94_RS02565	COG1473	amidohydrolase
INP94_RS02570	COG3069	C4-dicarboxylate transmembrane transporter activity
INP94_RS02580	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
INP94_RS02585	COG1522	sequence-specific DNA binding
INP94_RS02590	COG1288	antiporter activity
INP94_RS02595	COG0549	Belongs to the carbamate kinase family
INP94_RS02600	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
INP94_RS02605	COG0737	Belongs to the 5'-nucleotidase family
INP94_RS02615	COG0733	neurotransmitter:sodium symporter activity
INP94_RS02630	COG0028	Belongs to the TPP enzyme family
INP94_RS02650	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
INP94_RS02660	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
INP94_RS02665	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
INP94_RS02670	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
INP94_RS02695	COG3312	ion transport
INP94_RS02705	COG1733	regulation of RNA biosynthetic process
INP94_RS02710	COG0702	epimerase
INP94_RS02720	COG0716	FMN binding
INP94_RS02725	COG3074	FtsZ-dependent cytokinesis
INP94_RS02730	COG1494	fructose-1,6-bisphosphatase
INP94_RS02740	COG1285	pathogenesis
INP94_RS02745	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
INP94_RS02750	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
INP94_RS02755	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
INP94_RS02765	COG2267	carboxylic ester hydrolase activity
INP94_RS02770	COG0471	metal ion transport
INP94_RS02790	COG4104	PAAR repeat-containing protein
INP94_RS02790	COG3209	COG3209 Rhs family protein
INP94_RS02800	COG3209	COG3209 Rhs family protein
INP94_RS02800	COG4104	PAAR repeat-containing protein
INP94_RS02810	COG3209	COG3209 Rhs family protein
INP94_RS02810	COG4104	PAAR repeat-containing protein
INP94_RS02820	COG4104	PAAR repeat-containing protein
INP94_RS02820	COG3209	COG3209 Rhs family protein
INP94_RS02850	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
INP94_RS02860	COG1238	metal cluster binding
INP94_RS02865	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
INP94_RS02875	COG0248	Ppx GppA phosphatase
INP94_RS02880	COG2911	Protein conserved in bacteria
INP94_RS02885	COG0729	surface antigen
INP94_RS02890	COG1490	D-aminoacyl-tRNA deacylase activity
INP94_RS02905	COG2258	MOSC domain
INP94_RS02910	COG0433	COG0433 Predicted ATPase
INP94_RS02915	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
INP94_RS02920	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
INP94_RS02925	COG1045	serine acetyltransferase
INP94_RS02930	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
INP94_RS02935	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
INP94_RS02940	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
INP94_RS02945	COG0252	asparaginase activity
INP94_RS02950	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
INP94_RS02960	COG2990	Protein conserved in bacteria
INP94_RS02965	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
INP94_RS02970	COG0635	Involved in the biosynthesis of porphyrin-containing compound
INP94_RS02980	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
INP94_RS02985	COG1773	rubredoxin
INP94_RS02990	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
INP94_RS02995	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
INP94_RS03000	COG5557	Pfam Polysulphide reductase, NrfD
INP94_RS03005	COG0437	4 iron, 4 sulfur cluster binding
INP94_RS03010	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
INP94_RS03015	COG1704	LemA family
INP94_RS03025	COG0187	DNA topoisomerase II activity
INP94_RS03030	COG4988	ABC transporter
INP94_RS03035	COG1132	(ABC) transporter
INP94_RS03075	COG1921	L-seryl-tRNASec selenium transferase activity
INP94_RS03080	COG3276	selenocysteine insertion sequence binding
INP94_RS03115	COG1739	Uncharacterized protein family UPF0029
INP94_RS03120	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
INP94_RS03125	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
INP94_RS03155	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
INP94_RS03160	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
INP94_RS03160	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
INP94_RS03170	COG0569	domain protein
INP94_RS03175	COG1970	mechanosensitive ion channel activity
INP94_RS03195	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
INP94_RS03200	COG1309	transcriptional regulator
INP94_RS03205	COG0583	DNA-binding transcription factor activity
INP94_RS03210	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
INP94_RS03210	COG0678	peroxiredoxin activity
INP94_RS03215	COG1609	Transcriptional regulator
INP94_RS03225	COG1285	pathogenesis
INP94_RS03230	COG2211	Major facilitator Superfamily
INP94_RS03245	COG0705	Rhomboid family
INP94_RS03250	COG1349	DNA-binding transcription factor activity
INP94_RS03255	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
INP94_RS03260	COG0742	ribosomal rna small subunit methyltransferase
INP94_RS03265	COG0552	protein localization to endoplasmic reticulum
INP94_RS03270	COG2884	Cell division ATP-binding protein ftsE
INP94_RS03275	COG2177	Part of the ABC transporter FtsEX involved in
INP94_RS03280	COG0051	transcription antitermination factor activity, RNA binding
INP94_RS03285	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
INP94_RS03305	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
INP94_RS03320	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
INP94_RS03365	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
INP94_RS03385	COG0201	protein transport
INP94_RS03420	COG0564	pseudouridine synthase activity
INP94_RS03430	COG3201	nicotinamide mononucleotide transporter
INP94_RS03440	COG0513	Belongs to the DEAD box helicase family
INP94_RS03455	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
INP94_RS03495	COG0363	glucosamine-6-phosphate deaminase activity
INP94_RS03500	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
INP94_RS03505	COG1218	3'(2'),5'-bisphosphate nucleotidase
INP94_RS03515	COG1297	OPT oligopeptide transporter protein
INP94_RS03520	COG0494	nUDIX hydrolase
INP94_RS03525	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
INP94_RS03545	COG3700	Belongs to the class B bacterial acid phosphatase family
INP94_RS03570	COG1733	regulation of RNA biosynthetic process
INP94_RS03575	COG1047	Peptidyl-prolyl cis-trans
INP94_RS03585	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
INP94_RS03590	COG0585	pseudouridine synthase activity
INP94_RS03600	COG1238	metal cluster binding
INP94_RS03610	COG1388	LysM domain
INP94_RS03610	COG4942	peptidase
INP94_RS03615	COG0442	prolyl-tRNA aminoacylation
INP94_RS03620	COG4783	chaperone-mediated protein folding
INP94_RS03630	COG3266	domain, Protein
INP94_RS03635	COG0500	methyltransferase
INP94_RS03650	COG3059	membrane
INP94_RS03660	COG0584	glycerophosphoryl diester phosphodiesterase
INP94_RS03670	COG2271	Major facilitator Superfamily
INP94_RS03675	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
INP94_RS03685	COG0247	lactate metabolic process
INP94_RS03700	COG1522	sequence-specific DNA binding
INP94_RS03705	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
INP94_RS03710	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
INP94_RS03720	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
INP94_RS03730	COG0180	Tryptophanyl-tRNA synthetase
INP94_RS03735	COG3691	Protein conserved in bacteria
INP94_RS03740	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
INP94_RS03745	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
INP94_RS03750	COG0813	purine-nucleoside phosphorylase activity
INP94_RS03760	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
INP94_RS03765	COG2183	response to ionizing radiation
INP94_RS03785	COG3152	Membrane
INP94_RS03845	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
INP94_RS03850	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
INP94_RS03855	COG1126	abc transporter atp-binding protein
INP94_RS03860	COG0765	amino acid transport
INP94_RS03865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
INP94_RS03870	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
INP94_RS03900	COG0814	amino acid
INP94_RS03905	COG1435	thymidine kinase activity
INP94_RS03915	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
INP94_RS03925	COG0358	DNA primase activity
INP94_RS03930	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
INP94_RS03940	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
INP94_RS03945	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
INP94_RS03950	COG4972	Pilus assembly protein
INP94_RS03970	COG4796	Type ii and iii secretion system protein
INP94_RS03975	COG1040	competence protein
INP94_RS03985	COG0606	chelatase, subunit chli
INP94_RS03995	COG2990	Protein conserved in bacteria
INP94_RS04000	COG4608	Belongs to the ABC transporter superfamily
INP94_RS04005	COG0444	Belongs to the ABC transporter superfamily
INP94_RS04010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
INP94_RS04015	COG0601	transmembrane transport
INP94_RS04020	COG4166	transmembrane transport
INP94_RS04025	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
INP94_RS04030	COG3477	response to acidic pH
INP94_RS04035	COG2853	Lipoprotein
INP94_RS04040	COG0251	oxidation-reduction process
INP94_RS04065	COG1464	Belongs to the NlpA lipoprotein family
INP94_RS04080	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
INP94_RS04120	COG0635	Involved in the biosynthesis of porphyrin-containing compound
INP94_RS04125	COG0019	diaminopimelate decarboxylase activity
INP94_RS04135	COG0514	ATP-dependent DNA helicase (RecQ)
INP94_RS04140	COG1328	CTP reductase activity
INP94_RS04145	COG2364	Membrane
INP94_RS04150	COG0859	PFAM glycosyl transferase family 9
INP94_RS04155	COG3307	-O-antigen
INP94_RS04160	COG0191	fructose-bisphosphate aldolase activity
INP94_RS04170	COG3719	Belongs to the RNase T2 family
INP94_RS04175	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
INP94_RS04185	COG2814	Major facilitator Superfamily
INP94_RS04190	COG3850	Histidine kinase
INP94_RS04195	COG0812	UDP-N-acetylmuramate dehydrogenase activity
INP94_RS04205	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
INP94_RS04215	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
INP94_RS04220	COG1230	cation diffusion facilitator family transporter
INP94_RS04235	COG1116	anion transmembrane transporter activity
INP94_RS04255	COG5295	Hep Hag repeat protein
INP94_RS04255	COG5295	Hep Hag repeat protein
INP94_RS04260	COG1442	glycosyl transferase family 8
INP94_RS04285	COG0204	Acyl-transferase
INP94_RS04295	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
INP94_RS04300	COG1349	DNA-binding transcription factor activity
INP94_RS04305	COG0776	regulation of translation
INP94_RS04310	COG3068	Protein conserved in bacteria
INP94_RS04315	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
INP94_RS04335	COG0814	amino acid
INP94_RS04340	COG1561	YicC-like family, N-terminal region
INP94_RS04345	COG0354	folic acid binding
INP94_RS04350	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
INP94_RS04355	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
INP94_RS04360	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
INP94_RS04370	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
INP94_RS04375	COG3306	glycosyltransferase involved in LPS biosynthesis
INP94_RS04380	COG1441	menaquinone biosynthetic process
INP94_RS04390	COG0511	ligase activity, forming carbon-carbon bonds
INP94_RS04395	COG0439	Biotin carboxylase
INP94_RS04405	COG3924	membrane
INP94_RS04410	COG4145	pantothenate transmembrane transporter activity
INP94_RS04415	COG0697	spore germination
INP94_RS04425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
INP94_RS04430	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
INP94_RS04435	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
INP94_RS04440	COG0848	biopolymer transport protein
INP94_RS04445	COG0811	peptide transport
INP94_RS04450	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
INP94_RS04480	COG5295	Hep Hag repeat protein
INP94_RS04490	COG0659	secondary active sulfate transmembrane transporter activity
INP94_RS04495	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
INP94_RS04500	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
INP94_RS04505	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
INP94_RS04510	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
INP94_RS04535	COG0121	glutamine amidotransferase
INP94_RS04545	COG3036	rescue of stalled ribosome
INP94_RS04550	COG1393	Belongs to the ArsC family
INP94_RS04560	COG1720	tRNA m6t6A37 methyltransferase activity
INP94_RS04565	COG1575	Belongs to the MenA family. Type 1 subfamily
INP94_RS04575	COG0471	metal ion transport
INP94_RS04585	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
INP94_RS04590	COG4771	TonB-dependent receptor
INP94_RS04595	COG4771	TonB-dependent receptor
INP94_RS04605	COG1194	a g-specific adenine glycosylase
INP94_RS04630	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
INP94_RS04635	COG1252	NADH dehydrogenase
INP94_RS04645	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
INP94_RS04680	COG3718	enzyme involved in inositol metabolism
INP94_RS04695	COG0823	Involved in the tonB-independent uptake of proteins
INP94_RS04705	COG0673	inositol 2-dehydrogenase activity
INP94_RS04720	COG1129	ABC transporter
INP94_RS04725	COG1172	Belongs to the binding-protein-dependent transport system permease family
INP94_RS04730	COG0673	inositol 2-dehydrogenase activity
INP94_RS04740	COG3962	Belongs to the TPP enzyme family
INP94_RS04745	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
INP94_RS04760	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
INP94_RS04765	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
INP94_RS04770	COG1053	succinate dehydrogenase
INP94_RS04780	COG0814	amino acid
INP94_RS04785	COG1760	l-serine dehydratase
INP94_RS04790	COG1408	metallophosphoesterase
INP94_RS04795	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
INP94_RS04805	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
INP94_RS04810	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
INP94_RS04845	COG0646	methionine synthase
INP94_RS04845	COG1410	methionine synthase
INP94_RS04855	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
INP94_RS04870	COG0758	DNA mediated transformation
INP94_RS04875	COG3022	response to hydroperoxide
INP94_RS04890	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
INP94_RS04905	COG0545	Peptidyl-prolyl cis-trans isomerase
INP94_RS04910	COG0688	phosphatidylethanolamine metabolic process
INP94_RS04915	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
INP94_RS04920	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
INP94_RS04925	COG0754	glutathionylspermidine amidase activity
INP94_RS04930	COG3005	denitrification pathway
INP94_RS04935	COG3043	anaerobic respiration
INP94_RS04940	COG0348	domain, Protein
INP94_RS04945	COG0437	4 iron, 4 sulfur cluster binding
INP94_RS04950	COG0243	molybdopterin cofactor binding
INP94_RS04955	COG3062	negative regulation of establishment of protein localization
INP94_RS04960	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
INP94_RS04965	COG3171	Protein conserved in bacteria
INP94_RS04975	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
INP94_RS04980	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
INP94_RS04985	COG1309	transcriptional regulator
INP94_RS04990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
INP94_RS04995	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
INP94_RS05005	COG0814	amino acid
INP94_RS05010	COG2226	methyltransferase
INP94_RS05025	COG2194	sulfuric ester hydrolase activity
INP94_RS05055	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
INP94_RS05060	COG0575	Belongs to the CDS family
INP94_RS05065	COG0750	zinc metalloprotease
INP94_RS05075	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
INP94_RS05085	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
INP94_RS05095	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
INP94_RS05105	COG0471	metal ion transport
INP94_RS05105	COG0490	domain, Protein
INP94_RS05120	COG1027	Aspartate ammonia-lyase
INP94_RS05140	COG0006	proline dipeptidase activity
INP94_RS05145	COG0589	response to stress
INP94_RS05160	COG1210	Utp--glucose-1-phosphate uridylyltransferase
INP94_RS05165	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
INP94_RS05175	COG0789	Transcriptional regulator
INP94_RS05180	COG2608	mercury ion transmembrane transporter activity
INP94_RS05185	COG2217	Heavy metal translocating P-type atpase
INP94_RS05190	COG2205	protein histidine kinase activity
INP94_RS05195	COG0745	RESPONSE REGULATOR receiver
INP94_RS05200	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
INP94_RS05215	COG3083	sulfuric ester hydrolase activity
INP94_RS05220	COG0402	S-adenosylhomocysteine deaminase activity
INP94_RS05245	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
INP94_RS05255	COG0582	viral genome integration into host DNA
INP94_RS05260	COG1476	TRANSCRIPTIONal
INP94_RS05300	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
INP94_RS05310	COG0741	lytic transglycosylase activity
INP94_RS05315	COG2350	Protein conserved in bacteria
INP94_RS05320	COG1607	acyl-coa hydrolase
INP94_RS05335	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
INP94_RS05345	COG3691	Protein conserved in bacteria
INP94_RS05355	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
INP94_RS05370	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
INP94_RS05380	COG1108	ABC-type Mn2 Zn2 transport systems permease components
INP94_RS05385	COG1121	(ABC) transporter
INP94_RS05390	COG0739	heme binding
INP94_RS05395	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
INP94_RS05400	COG4605	iron ion homeostasis
INP94_RS05405	COG4604	ABC transporter, ATP-binding protein
INP94_RS05410	COG4607	ABC-type enterochelin transport system periplasmic component
INP94_RS05415	COG3283	Transcriptional regulator of aromatic amino acids metabolism
INP94_RS05420	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
INP94_RS05430	COG0564	pseudouridine synthase activity
INP94_RS05435	COG1530	ribonuclease E activity
INP94_RS05450	COG2056	Na+-H+ antiporter family
INP94_RS05460	COG0346	lactoylglutathione lyase activity
INP94_RS05475	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
INP94_RS05485	COG0494	nUDIX hydrolase
INP94_RS05495	COG0641	radical SAM
INP94_RS05500	COG0641	radical SAM
INP94_RS05525	COG1271	oxidase subunit
INP94_RS05530	COG1294	oxidase, subunit
INP94_RS05545	COG0824	Thioesterase
INP94_RS05550	COG0811	peptide transport
INP94_RS05555	COG0848	biopolymer transport protein
INP94_RS05560	COG3064	Membrane
INP94_RS05570	COG2885	chlorophyll binding
INP94_RS05590	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
INP94_RS05595	COG1959	2 iron, 2 sulfur cluster binding
INP94_RS05605	COG0822	iron-sulfur transferase activity
INP94_RS05620	COG0316	Belongs to the HesB IscA family
INP94_RS05625	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
INP94_RS05635	COG0443	Heat shock 70 kDa protein
INP94_RS05640	COG0633	Ferredoxin
INP94_RS05645	COG2975	iron-sulfur cluster assembly
INP94_RS05650	COG4211	Belongs to the binding-protein-dependent transport system permease family
INP94_RS05655	COG1129	ABC transporter
INP94_RS05660	COG1879	ABC-type sugar transport system periplasmic component
INP94_RS05665	COG1609	Transcriptional regulator
INP94_RS05670	COG1085	galactose-1-phosphate uridylyltransferase
INP94_RS05675	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
INP94_RS05680	COG2017	converts alpha-aldose to the beta-anomer
INP94_RS05685	COG4535	Mg2 and Co2 transporter CorC
INP94_RS05690	COG0815	Transfers the fatty acyl group on membrane lipoproteins
INP94_RS05695	COG1127	ABC transporter
INP94_RS05700	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
INP94_RS05705	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
INP94_RS05710	COG2854	intermembrane phospholipid transfer
INP94_RS05715	COG3113	response to antibiotic
INP94_RS05720	COG5007	Belongs to the BolA IbaG family
INP94_RS05730	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
INP94_RS05735	COG0460	homoserine dehydrogenase
INP94_RS05735	COG0527	aspartate kinase activity
INP94_RS05745	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
INP94_RS05750	COG2091	lysine biosynthetic process via aminoadipic acid
INP94_RS05755	COG0330	HflC and HflK could
INP94_RS05760	COG0330	HflC and HflK could
INP94_RS05785	COG0626	cystathionine gamma-synthase activity
INP94_RS05790	COG3118	belongs to the thioredoxin family
INP94_RS05795	COG1793	dna ligase
INP94_RS05805	COG1126	abc transporter atp-binding protein
INP94_RS05810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
INP94_RS05815	COG4215	(ABC) transporter
INP94_RS05820	COG4160	amino acid transport
INP94_RS05835	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
INP94_RS05850	COG1674	ftsk spoiiie
INP94_RS05855	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
INP94_RS05875	COG1222	aaa ATPase
INP94_RS05885	COG1966	Carbon starvation protein
INP94_RS05895	COG0275	rRNA processing
INP94_RS05900	COG3116	cell division
INP94_RS05905	COG0768	penicillin binding
INP94_RS05915	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
INP94_RS05930	COG0772	Belongs to the SEDS family
INP94_RS05935	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
INP94_RS05950	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
INP94_RS05955	COG0849	cell division
INP94_RS05960	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
INP94_RS05965	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
INP94_RS05970	COG0737	Belongs to the 5'-nucleotidase family
INP94_RS05975	COG1605	Chorismate mutase
INP94_RS05975	COG0077	Prephenate dehydratase
INP94_RS05980	COG2824	Alkylphosphonate utilization operon protein PhnA
INP94_RS05985	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
INP94_RS05995	COG1595	DNA-templated transcription, initiation
INP94_RS06010	COG3219	Protein conserved in bacteria
INP94_RS06015	COG3220	belongs to the UPF0276 family
INP94_RS06025	COG2259	Doxx family
INP94_RS06040	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
INP94_RS06045	COG0084	hydrolase, TatD family'
INP94_RS06050	COG0602	queuosine metabolic process
INP94_RS06060	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
INP94_RS06065	COG4988	ABC transporter
INP94_RS06070	COG0492	ferredoxin-NADP+ reductase activity
INP94_RS06075	COG3118	belongs to the thioredoxin family
INP94_RS06085	COG0471	metal ion transport
INP94_RS06090	COG1573	uracil-dna glycosylase
INP94_RS06095	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
INP94_RS06095	COG1328	CTP reductase activity
INP94_RS06100	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
INP94_RS06110	COG0497	DNA recombination
INP94_RS06120	COG3091	SprT-like family
INP94_RS06125	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
INP94_RS06130	COG1393	Belongs to the ArsC family
INP94_RS06155	COG1876	peptidase activity
INP94_RS06165	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
INP94_RS06170	COG1137	ATPase activity
INP94_RS06175	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
INP94_RS06180	COG3117	lipopolysaccharide transmembrane transporter activity
INP94_RS06190	COG0312	modulator of DNA gyrase
INP94_RS06195	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
INP94_RS06200	COG1160	GTP binding
INP94_RS06215	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
INP94_RS06225	COG1946	Acyl-CoA thioesterase
INP94_RS06230	COG0012	GTP binding
INP94_RS06235	COG0193	aminoacyl-tRNA hydrolase activity
INP94_RS06250	COG2850	peptidyl-arginine hydroxylation
INP94_RS06260	COG0494	nUDIX hydrolase
INP94_RS06265	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
INP94_RS06290	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
INP94_RS06295	COG0450	alkyl hydroperoxide reductase
INP94_RS06300	COG0626	cystathionine gamma-synthase activity
INP94_RS06305	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
INP94_RS06310	COG5413	integral membrane protein
INP94_RS06320	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
INP94_RS06325	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
INP94_RS06330	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
INP94_RS06340	COG0475	glutathione-regulated potassium exporter activity
INP94_RS06340	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
INP94_RS06350	COG2363	Small membrane protein
INP94_RS06355	COG1643	Atp-dependent helicase
INP94_RS06370	COG3069	C4-dicarboxylate transmembrane transporter activity
INP94_RS06375	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
INP94_RS06380	COG0617	tRNA 3'-terminal CCA addition
INP94_RS06385	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
INP94_RS06390	COG2333	competence protein COMEC
INP94_RS06390	COG0658	competence protein
INP94_RS06400	COG1663	tetraacyldisaccharide 4'-kinase activity
INP94_RS06405	COG2835	tetraacyldisaccharide 4'-kinase activity
INP94_RS06425	COG0861	Integral membrane protein TerC family
INP94_RS06430	COG3842	ATPase activity
INP94_RS06435	COG1178	ABC-type Fe3 transport system permease component
INP94_RS06440	COG1840	ABC-type Fe3 transport system, periplasmic component
INP94_RS06445	COG2918	glutathione biosynthetic process
INP94_RS06445	COG1181	Belongs to the D-alanine--D-alanine ligase family
INP94_RS06450	COG1702	phosphate starvation-inducible protein PhoH
INP94_RS06460	COG0561	phosphatase activity
INP94_RS06465	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
INP94_RS06475	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
INP94_RS06500	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
INP94_RS06505	COG0456	acetyltransferase
INP94_RS06510	COG3058	Necessary for formate dehydrogenase activity
INP94_RS06515	COG2864	formate dehydrogenase
INP94_RS06520	COG0437	4 iron, 4 sulfur cluster binding
INP94_RS06535	COG1840	ABC-type Fe3 transport system, periplasmic component
INP94_RS06540	COG0210	DNA helicase
INP94_RS06545	COG0601	transmembrane transport
INP94_RS06550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
INP94_RS06555	COG0444	Belongs to the ABC transporter superfamily
INP94_RS06560	COG4608	Belongs to the ABC transporter superfamily
INP94_RS06565	COG2814	Major facilitator Superfamily
INP94_RS06585	COG1840	ABC-type Fe3 transport system, periplasmic component
INP94_RS06590	COG1840	ABC-type Fe3 transport system, periplasmic component
INP94_RS06610	COG0583	DNA-binding transcription factor activity
INP94_RS06615	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
INP94_RS06620	COG1687	branched-chain amino acid
INP94_RS06645	COG0516	GMP reductase activity
INP94_RS06645	COG0517	IMP dehydrogenase activity
INP94_RS06650	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
INP94_RS06650	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
INP94_RS06685	COG0784	Response regulator, receiver
INP94_RS06685	COG5002	protein histidine kinase activity
INP94_RS06685	COG5002	protein histidine kinase activity
INP94_RS06685	COG0784	Response regulator, receiver
INP94_RS06685	COG2198	Histidine kinase
INP94_RS06685	COG2198	Histidine kinase
INP94_RS06690	COG1444	tRNA N-acetyltransferase activity
INP94_RS06700	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
INP94_RS06705	COG1090	epimerase
INP94_RS06715	COG0039	L-malate dehydrogenase activity
INP94_RS06720	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
INP94_RS06725	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
INP94_RS06740	COG4991	sh3 domain protein
INP94_RS06745	COG0306	phosphate transporter
INP94_RS06750	COG1392	Phosphate transport regulator
INP94_RS06755	COG3025	triphosphatase activity
INP94_RS06760	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
INP94_RS06765	COG1522	sequence-specific DNA binding
INP94_RS06775	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
INP94_RS06780	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
INP94_RS06785	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
INP94_RS06790	COG1177	transmembrane transport
INP94_RS06795	COG1176	ABC-type spermidine putrescine transport system, permease component I
INP94_RS06800	COG3842	ATPase activity
INP94_RS06810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
INP94_RS06815	COG3108	Peptidase M15
INP94_RS06820	COG2989	Protein conserved in bacteria
INP94_RS06825	COG0793	Belongs to the peptidase S41A family
INP94_RS06830	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
INP94_RS06835	COG2995	paraquat-inducible protein a
INP94_RS06840	COG3008	intermembrane lipid transfer
INP94_RS06845	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
INP94_RS06850	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
INP94_RS06850	COG0517	IMP dehydrogenase activity
INP94_RS06860	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
INP94_RS06930	COG4197	protein conserved in bacteria, prophage-related
INP94_RS07120	COG4695	Portal protein
INP94_RS07125	COG2249	NAD(P)H dehydrogenase (quinone) activity
INP94_RS07150	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
INP94_RS07175	COG3101	peptidyl-lysine hydroxylation
INP94_RS07180	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
INP94_RS07185	COG2890	protein-(glutamine-N5) methyltransferase activity
INP94_RS07190	COG2912	Transglutaminase-like superfamily
INP94_RS07200	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
INP94_RS07205	COG4591	ABC-type transport system involved in lipoprotein release permease component
INP94_RS07210	COG1136	(ABC) transporter
INP94_RS07215	COG4591	ABC-type transport system involved in lipoprotein release permease component
INP94_RS07220	COG3105	Protein conserved in bacteria
INP94_RS07225	COG0251	oxidation-reduction process
INP94_RS07235	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
INP94_RS07250	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
INP94_RS07255	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
INP94_RS07260	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
INP94_RS07265	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
INP94_RS07270	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
INP94_RS07275	COG0539	negative regulation of cytoplasmic translation
INP94_RS07285	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
INP94_RS07290	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
INP94_RS07300	COG0023	Translation Initiation Factor
INP94_RS07305	COG3094	Invasion gene expression up-regulator, SirB
INP94_RS07310	COG0488	(ABC) transporter
INP94_RS07315	COG3683	transport system, periplasmic component
INP94_RS07320	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
INP94_RS07325	COG0778	Nitroreductase
INP94_RS07330	COG1434	Gram-negative-bacterium-type cell wall biogenesis
INP94_RS07345	COG4178	(ABC) transporter
INP94_RS07350	COG4774	siderophore transport
INP94_RS07365	COG0469	pyruvate kinase activity
INP94_RS07370	COG0305	Participates in initiation and elongation during chromosome replication
INP94_RS07375	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
INP94_RS07395	COG1621	beta-fructofuranosidase activity
INP94_RS07405	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
INP94_RS07435	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
INP94_RS07440	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
INP94_RS07445	COG2431	L-lysine efflux transmembrane transporter activity
INP94_RS07450	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
INP94_RS07455	COG0298	carbon dioxide binding
INP94_RS07460	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
INP94_RS07465	COG0651	ATP synthesis coupled electron transport
INP94_RS07470	COG0650	Formate hydrogenlyase subunit 4
INP94_RS07475	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
INP94_RS07480	COG4237	Hydrogenase 4 membrane
INP94_RS07485	COG0651	ATP synthesis coupled electron transport
INP94_RS07490	COG3261	NADH dehydrogenase
INP94_RS07490	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
INP94_RS07495	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
INP94_RS07500	COG3260	NADH ubiquinone oxidoreductase 20
INP94_RS07510	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
INP94_RS07515	COG3383	formate dehydrogenase (NAD+) activity
INP94_RS07520	COG3383	formate dehydrogenase (NAD+) activity
INP94_RS07525	COG1122	ATPase activity
INP94_RS07530	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
INP94_RS07535	COG0310	cobalt ion transport
INP94_RS07540	COG0310	cobalt ion transport
INP94_RS07545	COG5266	PFAM Nickel transport complex, NikM subunit, transmembrane
INP94_RS07550	COG0789	Transcriptional regulator
INP94_RS07555	COG0375	protein maturation
INP94_RS07560	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
INP94_RS07565	COG0409	Hydrogenase expression formation protein
INP94_RS07570	COG0309	Hydrogenase expression formation protein (HypE)
INP94_RS07575	COG3099	Belongs to the UPF0263 family
INP94_RS07600	COG3306	glycosyltransferase involved in LPS biosynthesis
INP94_RS07610	COG1216	Glycosyl transferase, family 2
INP94_RS07615	COG1216	Glycosyl transferase, family 2
INP94_RS07620	COG2951	lytic endotransglycosylase activity
INP94_RS07625	COG1858	cytochrome C peroxidase
INP94_RS07630	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
INP94_RS07635	COG4139	cobalamin transport
INP94_RS07670	COG0577	efflux transmembrane transporter activity
INP94_RS07670	COG1136	(ABC) transporter
INP94_RS07680	COG0577	efflux transmembrane transporter activity
INP94_RS07695	COG0672	)-iron permease
INP94_RS07700	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
INP94_RS07705	COG3112	Uncharacterised protein family (UPF0231)
INP94_RS07710	COG0316	Belongs to the HesB IscA family
INP94_RS07715	COG0024	Methionine aminopeptidase
INP94_RS07725	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
INP94_RS07730	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
INP94_RS07785	COG1199	ATP-dependent helicase activity
INP94_RS07790	COG1214	PFAM Peptidase M22, glycoprotease
INP94_RS07795	COG3065	identical protein binding
INP94_RS07800	COG0318	PFAM AMP-dependent synthetase and ligase
INP94_RS07805	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
INP94_RS07810	COG0857	belongs to the CobB CobQ family
INP94_RS07810	COG0280	phosphate acetyltransferase
INP94_RS07820	COG3092	negative regulation of chromosome organization
INP94_RS07825	COG1286	toxin biosynthetic process
INP94_RS07830	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
INP94_RS07835	COG2027	D-alanyl-D-alanine carboxypeptidase
INP94_RS07840	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
INP94_RS07845	COG1534	Rna-binding protein
INP94_RS07855	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
INP94_RS07860	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
INP94_RS07865	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
INP94_RS07870	COG2062	phosphohistidine phosphatase, SixA
INP94_RS07885	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
INP94_RS07890	COG0288	reversible hydration of carbon dioxide
INP94_RS07900	COG0616	signal peptide processing
INP94_RS07915	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
INP94_RS07925	COG0776	regulation of translation
INP94_RS07930	COG0791	NLP P60 protein
INP94_RS07935	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
INP94_RS07950	COG0625	glutathione transferase activity
INP94_RS07955	COG2969	positive regulation of protein catabolic process
INP94_RS07970	COG0133	tryptophan synthase activity
INP94_RS07975	COG4221	oxidoreductase activity
INP94_RS07980	COG0135	phosphoribosylanthranilate isomerase activity
INP94_RS07980	COG0134	indole-3-glycerol-phosphate synthase activity
INP94_RS07990	COG1942	4-Oxalocrotonate Tautomerase
INP94_RS07995	COG0512	Glutamine amidotransferase of anthranilate synthase
INP94_RS08000	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
INP94_RS08015	COG0676	glucose-6-phosphate 1-epimerase activity
INP94_RS08025	COG0291	Belongs to the bacterial ribosomal protein bL35 family
INP94_RS08030	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
INP94_RS08045	COG0783	Belongs to the Dps family
INP94_RS08050	COG0747	negative chemotaxis
INP94_RS08055	COG0601	transmembrane transport
INP94_RS08060	COG0444	Belongs to the ABC transporter superfamily
INP94_RS08065	COG4608	Belongs to the ABC transporter superfamily
INP94_RS08090	COG3585	molybdate ion transport
INP94_RS08095	COG2920	part of a sulfur-relay system
INP94_RS08160	COG0629	single-stranded DNA binding
INP94_RS08195	COG3561	AntA/AntB antirepressor
INP94_RS08300	COG3728	DNA packaging
INP94_RS08305	COG1783	phage Terminase large subunit
INP94_RS08310	COG3567	Phage-associated protein, HI1409 family
INP94_RS08315	COG2369	cell adhesion
INP94_RS08325	COG3566	protein conserved in bacteria
INP94_RS08415	COG5301	cellulose 1,4-beta-cellobiosidase activity
INP94_RS08440	COG0582	viral genome integration into host DNA
INP94_RS08450	COG1528	Iron-storage protein
INP94_RS08455	COG1528	Iron-storage protein
INP94_RS08460	COG2925	Exonuclease
INP94_RS08465	COG0697	spore germination
INP94_RS08470	COG3586	endonuclease activity
INP94_RS08480	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
INP94_RS08485	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
INP94_RS08495	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
INP94_RS08500	COG0589	response to stress
INP94_RS08505	COG5266	PFAM Nickel transport complex, NikM subunit, transmembrane
INP94_RS08515	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
INP94_RS08520	COG0583	DNA-binding transcription factor activity
INP94_RS08525	COG0613	PHP domain protein
INP94_RS08530	COG0167	dihydroorotate dehydrogenase activity
INP94_RS08535	COG4166	transmembrane transport
INP94_RS08540	COG0308	aminopeptidase N
INP94_RS08545	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
INP94_RS08550	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
INP94_RS08555	COG1448	Aminotransferase
INP94_RS08565	COG0314	molybdopterin synthase activity
INP94_RS08570	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
INP94_RS08575	COG0315	cyclic pyranopterin monophosphate synthase activity
INP94_RS08580	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
INP94_RS08600	COG0142	geranyltranstransferase activity
INP94_RS08605	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
INP94_RS08610	COG3610	response to peptide
INP94_RS08615	COG2966	Psort location CytoplasmicMembrane, score
INP94_RS08620	COG2999	glutathione oxidoreductase activity
INP94_RS08625	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
INP94_RS08630	COG1074	ATP-dependent DNA helicase activity
INP94_RS08655	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
INP94_RS08660	COG2252	PERMEase
INP94_RS08665	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
INP94_RS08670	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
INP94_RS08675	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
INP94_RS08680	COG1067	ATP-dependent peptidase activity
INP94_RS08690	COG1278	Cold shock
INP94_RS08695	COG3140	Belongs to the UPF0181 family
INP94_RS08715	COG1289	transmembrane transporter activity
INP94_RS08720	COG4657	Part of a membrane complex involved in electron transport
INP94_RS08730	COG4656	Part of a membrane complex involved in electron transport
INP94_RS08750	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
INP94_RS08755	COG0733	neurotransmitter:sodium symporter activity
INP94_RS08765	COG0488	(ABC) transporter
INP94_RS08775	COG1346	cytolysis
INP94_RS08785	COG1525	nuclease
INP94_RS08790	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
INP94_RS08795	COG2166	iron-sulfur cluster assembly
INP94_RS08800	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
INP94_RS08805	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
INP94_RS08805	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
INP94_RS08810	COG0287	Prephenate dehydrogenase
INP94_RS08810	COG1605	Chorismate mutase
INP94_RS08820	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
INP94_RS08830	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
INP94_RS08835	COG0195	Participates in both transcription termination and antitermination
INP94_RS08870	COG3209	COG3209 Rhs family protein
INP94_RS08870	COG4104	PAAR repeat-containing protein
INP94_RS08915	COG3209	COG3209 Rhs family protein
INP94_RS08915	COG4104	PAAR repeat-containing protein
INP94_RS08925	COG3501	Rhs element vgr protein
INP94_RS08940	COG0642	Histidine kinase
INP94_RS08945	COG0745	RESPONSE REGULATOR receiver
INP94_RS08950	COG3111	PFAM Bacterial OB fold (BOF) protein
INP94_RS08960	COG0633	Ferredoxin
INP94_RS08970	COG1280	lysine exporter protein (LysE YggA)
INP94_RS08975	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
INP94_RS08980	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
INP94_RS08990	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
INP94_RS08995	COG0058	SHG alpha-glucan phosphorylase activity
INP94_RS09010	COG1523	belongs to the glycosyl hydrolase 13 family
INP94_RS09015	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
INP94_RS09020	COG1640	4-alpha-glucanotransferase
INP94_RS09035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
INP94_RS09040	COG1136	(ABC) transporter
INP94_RS09040	COG0577	efflux transmembrane transporter activity
INP94_RS09045	COG1538	Outer membrane efflux protein
INP94_RS09055	COG0489	protein tyrosine kinase activity
INP94_RS09075	COG3133	Outer membrane lipoprotein
INP94_RS09085	COG3102	Protein conserved in bacteria
INP94_RS09095	COG2840	Smr protein MutS2
INP94_RS09100	COG2890	protein-(glutamine-N5) methyltransferase activity
INP94_RS09110	COG0583	DNA-binding transcription factor activity
INP94_RS09115	COG1187	pseudouridine synthase activity
INP94_RS09120	COG0009	L-threonylcarbamoyladenylate synthase
INP94_RS09125	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
INP94_RS09135	COG0508	dehydrogenase complex catalyzes the overall conversion of
INP94_RS09140	COG0567	Dehydrogenase, E1 component
INP94_RS09145	COG1555	photosystem II stabilization
INP94_RS09150	COG0670	Belongs to the BI1 family
INP94_RS09175	COG3501	Rhs element vgr protein
INP94_RS09260	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
INP94_RS09265	COG0708	Exodeoxyribonuclease III
INP94_RS09275	COG0564	pseudouridine synthase activity
INP94_RS09285	COG1757	Na H antiporter
INP94_RS09290	COG2916	Histone family protein nucleoid-structuring protein H-NS
INP94_RS09295	COG0788	formyltetrahydrofolate deformylase activity
INP94_RS09305	COG2814	Major facilitator Superfamily
INP94_RS09315	COG0303	'Molybdopterin
INP94_RS09320	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
INP94_RS09325	COG2391	methyltransferase activity
INP94_RS09330	COG0425	Belongs to the sulfur carrier protein TusA family
INP94_RS09340	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
INP94_RS09345	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
INP94_RS09355	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
INP94_RS09360	COG3107	peptidoglycan biosynthetic process
INP94_RS09370	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
INP94_RS09375	COG2823	Periplasmic or secreted lipoprotein
INP94_RS09380	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
INP94_RS09390	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
INP94_RS09400	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
INP94_RS09405	COG1914	H( )-stimulated, divalent metal cation uptake system
INP94_RS09415	COG1984	allophanate hydrolase subunit 2
INP94_RS09420	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
INP94_RS09430	COG0795	lipopolysaccharide-transporting ATPase activity
INP94_RS09435	COG0795	lipopolysaccharide-transporting ATPase activity
INP94_RS09445	COG3021	interspecies interaction between organisms
INP94_RS09450	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
INP94_RS09455	COG1368	sulfuric ester hydrolase activity
INP94_RS09460	COG0281	malic enzyme
INP94_RS09460	COG0280	phosphate acetyltransferase
INP94_RS09465	COG3955	Domain of unknown function (DUF1919)
INP94_RS09470	COG1187	pseudouridine synthase activity
INP94_RS09475	COG2814	Major facilitator Superfamily
INP94_RS09480	COG1115	amino acid carrier protein
INP94_RS09490	COG0671	phosphoesterase, PA-phosphatase related
INP94_RS09510	COG0187	DNA topoisomerase II activity
INP94_RS09520	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
INP94_RS09525	COG0786	glutamate:sodium symporter activity
INP94_RS09530	COG0285	dihydrofolate synthase activity
INP94_RS09545	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
INP94_RS09550	COG0586	Pfam SNARE associated Golgi protein
INP94_RS09555	COG0307	riboflavin synthase, alpha
INP94_RS09560	COG0534	Mate efflux family protein
INP94_RS09570	COG1305	Transglutaminase-like
INP94_RS09580	COG2608	mercury ion transmembrane transporter activity
INP94_RS09590	COG3106	COG3106 Predicted ATPase
INP94_RS09595	COG4166	transmembrane transport
INP94_RS09600	COG4168	peptide transport system, permease
INP94_RS09605	COG4171	peptide transport system, permease
INP94_RS09610	COG4172	Belongs to the ABC transporter superfamily
INP94_RS09615	COG4172	Belongs to the ABC transporter superfamily
INP94_RS09625	COG0616	signal peptide processing
INP94_RS09630	COG0778	Nitroreductase
INP94_RS09635	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
INP94_RS09640	COG2949	membrane
INP94_RS09645	COG0527	aspartate kinase activity
INP94_RS09665	COG3842	ATPase activity
INP94_RS09670	COG1178	ABC-type Fe3 transport system permease component
INP94_RS09675	COG3842	ATPase activity
INP94_RS09695	COG0440	acetolactate synthase activity
INP94_RS09700	COG0028	Belongs to the TPP enzyme family
INP94_RS09705	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
INP94_RS09710	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
INP94_RS09710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
INP94_RS09715	COG1530	ribonuclease E activity
INP94_RS09720	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
INP94_RS09735	COG0583	DNA-binding transcription factor activity
INP94_RS09740	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
INP94_RS09745	COG0318	PFAM AMP-dependent synthetase and ligase
INP94_RS09745	COG0204	Acyl-transferase
INP94_RS09755	COG4166	transmembrane transport
INP94_RS09760	COG2832	Protein of unknown function (DUF454)
INP94_RS09765	COG0339	signal peptide processing
INP94_RS09780	COG1120	ATPase activity
INP94_RS09785	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
INP94_RS09790	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
INP94_RS09795	COG0157	Belongs to the NadC ModD family
INP94_RS09800	COG3842	ATPase activity
INP94_RS09805	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
INP94_RS09810	COG0725	ABC transporter, periplasmic molybdate-binding protein
INP94_RS09815	COG1120	ATPase activity
INP94_RS09820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
INP94_RS09825	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
INP94_RS09840	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
INP94_RS09840	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
INP94_RS09845	COG1560	Kdo2-lipid A biosynthetic process
INP94_RS09865	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
INP94_RS09870	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
INP94_RS09880	COG1263	PTS System
INP94_RS09880	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
INP94_RS09880	COG2190	(PTS) system
INP94_RS09890	COG0058	SHG alpha-glucan phosphorylase activity
INP94_RS09895	COG1640	4-alpha-glucanotransferase
INP94_RS09900	COG1609	Transcriptional regulator
INP94_RS09905	COG1275	C4-dicarboxylate transporter malic acid transport protein
INP94_RS09910	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
INP94_RS09915	COG2841	Protein conserved in bacteria
INP94_RS09930	COG2860	membrane
INP94_RS09940	COG2354	Protein conserved in bacteria
INP94_RS09945	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
INP94_RS09955	COG1560	Kdo2-lipid A biosynthetic process
INP94_RS09960	COG0730	response to heat
INP94_RS09965	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
INP94_RS09975	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
INP94_RS09975	COG3264	Mechanosensitive ion channel
INP94_RS09980	COG0318	PFAM AMP-dependent synthetase and ligase
INP94_RS09985	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
INP94_RS09990	COG0596	Alpha beta hydrolase
INP94_RS09995	COG0716	FMN binding
INP94_RS10000	COG0735	belongs to the Fur family
INP94_RS10015	COG2895	sulfate adenylyltransferase (ATP) activity
INP94_RS10030	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
INP94_RS10030	COG1648	precorrin-2 dehydrogenase activity
INP94_RS10035	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
INP94_RS10045	COG4208	sulfate ABC transporter
INP94_RS10050	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
INP94_RS10055	COG0137	argininosuccinate synthase activity
INP94_RS10060	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
INP94_RS10100	COG3698	Phosphodiester glycosidase
INP94_RS10105	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
INP94_RS10115	COG2226	methyltransferase
INP94_RS10125	COG1944	ATP diphosphatase activity
INP94_RS10130	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
INP94_RS10135	COG3381	protein complex oligomerization
INP94_RS10140	COG2249	NAD(P)H dehydrogenase (quinone) activity
INP94_RS10145	COG1585	Membrane protein implicated in regulation of membrane protease activity
INP94_RS10150	COG0330	HflC and HflK could
INP94_RS10155	COG1119	ATPase activity
INP94_RS10165	COG2932	Transcriptional regulator
INP94_RS10170	COG0791	NLP P60 protein
INP94_RS10175	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
INP94_RS10180	COG0508	dehydrogenase complex catalyzes the overall conversion of
INP94_RS10185	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
INP94_RS10195	COG5339	Protein conserved in bacteria
INP94_RS10200	COG0443	Heat shock 70 kDa protein
INP94_RS10215	COG0484	heat shock protein binding
INP94_RS10220	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
INP94_RS10225	COG4149	molybdate abc transporter
INP94_RS10230	COG0725	ABC transporter, periplasmic molybdate-binding protein
INP94_RS10235	COG2005	Transcriptional regulator
INP94_RS10245	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
INP94_RS10250	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
INP94_RS10250	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
INP94_RS10260	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
INP94_RS10275	COG4795	General secretion pathway protein
INP94_RS10280	COG2165	general secretion pathway protein
INP94_RS10285	COG0483	inositol monophosphate 1-phosphatase activity
INP94_RS10295	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
INP94_RS10300	COG1178	ABC-type Fe3 transport system permease component
INP94_RS10305	COG4143	(ABC) transporter
INP94_RS10315	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
INP94_RS10325	COG1704	LemA family
INP94_RS10335	COG0277	FAD linked oxidase domain protein
INP94_RS10335	COG0247	lactate metabolic process
INP94_RS10340	COG2050	protein possibly involved in aromatic compounds catabolism
INP94_RS10345	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
INP94_RS10385	COG2927	DNA polymerase III (CHI subunit)
INP94_RS10390	COG0114	fumarate hydratase activity
INP94_RS10395	COG2268	Band 7 protein
INP94_RS10405	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
INP94_RS10415	COG1482	cell wall glycoprotein biosynthetic process
INP94_RS10420	COG2190	(PTS) system
INP94_RS10425	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
INP94_RS10430	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
INP94_RS10435	COG1162	GTPase activity
INP94_RS10455	COG0802	atpase or kinase
INP94_RS10460	COG0860	N-Acetylmuramoyl-L-alanine amidase
INP94_RS10460	COG1388	LysM domain
INP94_RS10475	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
INP94_RS10505	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
INP94_RS10510	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
INP94_RS10515	COG1758	RNA polymerase activity
INP94_RS10525	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
INP94_RS10530	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
INP94_RS10535	COG1022	Amp-dependent synthetase and ligase
INP94_RS10545	COG4536	flavin adenine dinucleotide binding
INP94_RS10550	COG4137	Cytochrome C assembly protein
INP94_RS10555	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
INP94_RS10575	COG2233	PERMEase
INP94_RS10580	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
INP94_RS10595	COG0346	lactoylglutathione lyase activity
INP94_RS10610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
INP94_RS10615	COG1138	Cytochrome C-type biogenesis protein
INP94_RS10620	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
INP94_RS10625	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
INP94_RS10630	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
INP94_RS10635	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
INP94_RS10640	COG4133	protoheme IX ABC transporter activity
INP94_RS10645	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
INP94_RS10655	COG2976	Protein conserved in bacteria
INP94_RS10665	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
INP94_RS10670	COG1426	Protein conserved in bacteria
INP94_RS10675	COG3063	Type IV pilus biogenesis stability protein PilW
INP94_RS10690	COG1686	Belongs to the peptidase S11 family
INP94_RS10700	COG1121	(ABC) transporter
INP94_RS10705	COG1108	ABC-type Mn2 Zn2 transport systems permease components
INP94_RS10710	COG1108	ABC-type Mn2 Zn2 transport systems permease components
INP94_RS10720	COG1472	Belongs to the glycosyl hydrolase 3 family
INP94_RS10725	COG5633	Lipoprotein
INP94_RS10730	COG0537	adenosine 5'-monophosphoramidase activity
INP94_RS10735	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
INP94_RS10740	COG1971	Probably functions as a manganese efflux pump
INP94_RS10755	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
INP94_RS10760	COG0594	ribonuclease P activity