locus-tag	class	description
AL518_RS00010	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AL518_RS00020	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AL518_RS00025	COG0783	Belongs to the Dps family
AL518_RS00035	COG0697	spore germination
AL518_RS00045	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AL518_RS00055	COG1846	Transcriptional regulator
AL518_RS00065	COG1566	PFAM secretion protein HlyD family protein
AL518_RS00070	COG2814	Major facilitator Superfamily
AL518_RS00085	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL518_RS00090	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AL518_RS00095	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AL518_RS00105	COG2860	membrane
AL518_RS00110	COG2188	Transcriptional regulator
AL518_RS00115	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL518_RS00115	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL518_RS00115	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL518_RS00120	COG0383	alpha-mannosidase activity
AL518_RS00135	COG2764	glyoxalase bleomycin resistance protein dioxygenase
AL518_RS00140	COG0316	Belongs to the HesB IscA family
AL518_RS00150	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AL518_RS00160	COG0519	Catalyzes the synthesis of GMP from XMP
AL518_RS00160	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AL518_RS00165	COG0517	IMP dehydrogenase activity
AL518_RS00165	COG0516	GMP reductase activity
AL518_RS00170	COG1570	exodeoxyribonuclease VII activity
AL518_RS00175	COG1263	PTS System
AL518_RS00175	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL518_RS00180	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AL518_RS00185	COG1645	bacterial-type flagellum-dependent swarming motility
AL518_RS00195	COG1160	GTP binding
AL518_RS00200	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL518_RS00205	COG2976	Protein conserved in bacteria
AL518_RS00215	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AL518_RS00240	COG4953	penicillin-binding protein 1C
AL518_RS00245	COG2373	Large extracellular alpha-helical protein
AL518_RS00260	COG2975	iron-sulfur cluster assembly
AL518_RS00265	COG0633	Ferredoxin
AL518_RS00270	COG0443	Heat shock 70 kDa protein
AL518_RS00275	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AL518_RS00285	COG0822	iron-sulfur transferase activity
AL518_RS00295	COG1959	2 iron, 2 sulfur cluster binding
AL518_RS00300	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AL518_RS00305	COG0483	inositol monophosphate 1-phosphatase activity
AL518_RS00310	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AL518_RS00315	COG3683	transport system, periplasmic component
AL518_RS00320	COG3711	transcriptional antiterminator
AL518_RS00330	COG1017	nitric oxide dioxygenase activity
AL518_RS00330	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL518_RS00350	COG2814	Major facilitator Superfamily
AL518_RS00350	COG0477	Major facilitator Superfamily
AL518_RS00355	COG0457	Tetratricopeptide repeat
AL518_RS00360	COG1940	carbohydrate kinase activity
AL518_RS00375	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AL518_RS00400	COG3716	PTS system mannose fructose sorbose family IID component
AL518_RS00405	COG3715	PTS system
AL518_RS00410	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL518_RS00415	COG2222	sugar isomerase
AL518_RS00420	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
AL518_RS00425	COG1349	DNA-binding transcription factor activity
AL518_RS00435	COG4807	Protein conserved in bacteria
AL518_RS00445	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL518_RS00450	COG0842	Transport permease protein
AL518_RS00455	COG1131	(ABC) transporter
AL518_RS00460	COG0745	RESPONSE REGULATOR receiver
AL518_RS00465	COG2205	protein histidine kinase activity
AL518_RS00470	COG4452	Inner membrane protein CreD
AL518_RS00475	COG0288	reversible hydration of carbon dioxide
AL518_RS00495	COG0778	Nitroreductase
AL518_RS00500	COG1012	belongs to the aldehyde dehydrogenase family
AL518_RS00505	COG1177	transmembrane transport
AL518_RS00510	COG1176	ABC-type spermidine putrescine transport system, permease component I
AL518_RS00515	COG3842	ATPase activity
AL518_RS00520	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AL518_RS00530	COG0583	DNA-binding transcription factor activity
AL518_RS00550	COG2226	methyltransferase
AL518_RS00560	COG1388	LysM domain
AL518_RS00560	COG0741	lytic transglycosylase activity
AL518_RS00565	COG3021	interspecies interaction between organisms
AL518_RS00600	COG0542	response to heat
AL518_RS00610	COG0564	pseudouridine synthase activity
AL518_RS00620	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL518_RS00625	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AL518_RS00630	COG1605	Chorismate mutase
AL518_RS00630	COG0077	Prephenate dehydratase
AL518_RS00635	COG0287	Prephenate dehydrogenase
AL518_RS00635	COG1605	Chorismate mutase
AL518_RS00640	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL518_RS00645	COG3279	Response regulator of the LytR AlgR family
AL518_RS00655	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AL518_RS00660	COG3137	Salt-induced outer membrane protein
AL518_RS00670	COG0336	Belongs to the RNA methyltransferase TrmD family
AL518_RS00680	COG0228	four-way junction DNA binding
AL518_RS00685	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AL518_RS00690	COG4137	Cytochrome C assembly protein
AL518_RS00695	COG4536	flavin adenine dinucleotide binding
AL518_RS00710	COG1238	metal cluster binding
AL518_RS00715	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL518_RS00745	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AL518_RS00750	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AL518_RS00755	COG2137	regulation of response to DNA damage stimulus
AL518_RS00770	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL518_RS00775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL518_RS00780	COG2207	Transcriptional regulator
AL518_RS00785	COG2951	lytic endotransglycosylase activity
AL518_RS00790	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AL518_RS00795	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AL518_RS00800	COG4942	peptidase
AL518_RS00800	COG1388	LysM domain
AL518_RS00805	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AL518_RS00820	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AL518_RS00840	COG1051	belongs to the nudix hydrolase family
AL518_RS00845	COG3066	DNA modification
AL518_RS00850	COG0861	Integral membrane protein TerC family
AL518_RS00860	COG1785	Belongs to the alkaline phosphatase family
AL518_RS00865	COG0667	Aldo Keto reductase
AL518_RS00870	COG0477	Major facilitator Superfamily
AL518_RS00875	COG0204	Acyl-transferase
AL518_RS00875	COG0318	PFAM AMP-dependent synthetase and ligase
AL518_RS00885	COG1609	Transcriptional regulator
AL518_RS00890	COG1609	Transcriptional regulator
AL518_RS00900	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL518_RS00905	COG0651	ATP synthesis coupled electron transport
AL518_RS00910	COG0650	Formate hydrogenlyase subunit 4
AL518_RS00915	COG3261	NADH dehydrogenase
AL518_RS00915	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
AL518_RS00920	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL518_RS00925	COG3260	NADH ubiquinone oxidoreductase 20
AL518_RS00935	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AL518_RS00955	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL518_RS00960	COG3383	formate dehydrogenase (NAD+) activity
AL518_RS00965	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AL518_RS00975	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AL518_RS00980	COG0298	carbon dioxide binding
AL518_RS00985	COG0409	Hydrogenase expression formation protein
AL518_RS00990	COG0309	Hydrogenase expression formation protein (HypE)
AL518_RS01000	COG3604	Transcriptional regulator
AL518_RS01010	COG0583	DNA-binding transcription factor activity
AL518_RS01025	COG3539	Fimbrial protein
AL518_RS01035	COG3188	usher protein
AL518_RS01040	COG3121	Chaperone
AL518_RS01050	COG3539	Fimbrial protein
AL518_RS01055	COG3539	Fimbrial protein
AL518_RS01085	COG1585	Membrane protein implicated in regulation of membrane protease activity
AL518_RS01090	COG2268	Band 7 protein
AL518_RS01150	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AL518_RS01155	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL518_RS01160	COG4974	Belongs to the 'phage' integrase family
AL518_RS01165	COG0716	FMN binding
AL518_RS01175	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AL518_RS01180	COG0354	folic acid binding
AL518_RS01195	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AL518_RS01200	COG3248	Nucleoside-binding outer membrane protein
AL518_RS01205	COG1272	protein, Hemolysin III
AL518_RS01210	COG1115	amino acid carrier protein
AL518_RS01230	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AL518_RS01230	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AL518_RS01235	COG0509	glycine decarboxylation via glycine cleavage system
AL518_RS01240	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AL518_RS01245	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL518_RS01250	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL518_RS01255	COG0006	proline dipeptidase activity
AL518_RS01260	COG3079	Belongs to the UPF0149 family
AL518_RS01265	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AL518_RS01275	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AL518_RS01280	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL518_RS01300	COG1279	arginine transmembrane transporter activity
AL518_RS01310	COG0191	fructose-bisphosphate aldolase activity
AL518_RS01320	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AL518_RS01325	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AL518_RS01330	COG0501	Belongs to the peptidase M48B family
AL518_RS01335	COG0501	Belongs to the peptidase M48B family
AL518_RS01350	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AL518_RS01360	COG1335	isochorismatase
AL518_RS01375	COG2864	formate dehydrogenase
AL518_RS01380	COG0437	4 iron, 4 sulfur cluster binding
AL518_RS01390	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AL518_RS01405	COG0010	Belongs to the arginase family
AL518_RS01415	COG1166	arginine decarboxylase activity
AL518_RS01430	COG2814	Major facilitator Superfamily
AL518_RS01450	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AL518_RS01455	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AL518_RS01465	COG1328	CTP reductase activity
AL518_RS01470	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AL518_RS01475	COG0435	Glutathione S-transferase
AL518_RS01480	COG2259	Doxx family
AL518_RS01490	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
AL518_RS01495	COG4575	ribosome binding
AL518_RS01510	COG0586	Pfam SNARE associated Golgi protein
AL518_RS01520	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AL518_RS01530	COG2271	Major facilitator Superfamily
AL518_RS01540	COG0246	Mannitol dehydrogenase
AL518_RS01545	COG2721	sulfolactate sulfo-lyase activity
AL518_RS01555	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AL518_RS01560	COG0084	hydrolase, TatD family'
AL518_RS01565	COG4667	esterase of the alpha-beta hydrolase superfamily
AL518_RS01575	COG5487	UPF0391 membrane protein
AL518_RS01580	COG2823	Periplasmic or secreted lipoprotein
AL518_RS01585	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AL518_RS01590	COG0456	acetyltransferase
AL518_RS01595	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
AL518_RS01600	COG2813	Specifically methylates the guanine in position
AL518_RS01625	COG3706	GGDEF domain
AL518_RS01630	COG4114	ferric iron reductase
AL518_RS01635	COG3152	Membrane
AL518_RS01640	COG3152	Membrane
AL518_RS01645	COG4774	siderophore transport
AL518_RS01650	COG3486	L-lysine 6-monooxygenase (NADPH) activity
AL518_RS01670	COG3384	dioxygenase
AL518_RS01685	COG2960	long-chain fatty acid transporting porin activity
AL518_RS01690	COG0531	amino acid
AL518_RS01700	COG1560	Kdo2-lipid A biosynthetic process
AL518_RS01715	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AL518_RS01720	COG3025	triphosphatase activity
AL518_RS01725	COG1392	Phosphate transport regulator
AL518_RS01730	COG0306	phosphate transporter
AL518_RS01735	COG4991	sh3 domain protein
AL518_RS01740	COG0617	tRNA 3'-terminal CCA addition
AL518_RS01745	COG1968	undecaprenyl-diphosphatase activity
AL518_RS01750	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AL518_RS01755	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AL518_RS01765	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AL518_RS01770	COG0358	DNA primase activity
AL518_RS01775	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AL518_RS01780	COG3663	DNA glycosylase
AL518_RS01795	COG0446	pyridine nucleotide-disulphide oxidoreductase
AL518_RS01795	COG1902	pentaerythritol trinitrate reductase activity
AL518_RS01800	COG3111	PFAM Bacterial OB fold (BOF) protein
AL518_RS01810	COG0642	Histidine kinase
AL518_RS01815	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AL518_RS01820	COG2813	Specifically methylates the guanine in position
AL518_RS01825	COG1451	nucleotide metabolic process
AL518_RS01830	COG0673	inositol 2-dehydrogenase activity
AL518_RS01835	COG0697	spore germination
AL518_RS01840	COG0519	Catalyzes the synthesis of GMP from XMP
AL518_RS01840	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AL518_RS01845	COG0861	Integral membrane protein TerC family
AL518_RS01860	COG0583	DNA-binding transcription factor activity
AL518_RS01865	COG1741	Belongs to the pirin family
AL518_RS01875	COG0602	queuosine metabolic process
AL518_RS01880	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AL518_RS01885	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AL518_RS01890	COG3639	organic phosphonate transmembrane transporter activity
AL518_RS01895	COG2188	Transcriptional regulator
AL518_RS01900	COG3624	Phosphonate C-P lyase system protein PhnG
AL518_RS01905	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
AL518_RS01910	COG3626	phosphonate metabolism
AL518_RS01915	COG3627	carbon phosphorus lyase activity
AL518_RS01920	COG4107	phosphonate C-P lyase system protein PhnK
AL518_RS01925	COG4778	phosphonate C-P lyase system protein PhnL
AL518_RS01930	COG3454	Phosphonate metabolism
AL518_RS01935	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AL518_RS01940	COG0456	acetyltransferase
AL518_RS01945	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AL518_RS01950	COG0702	epimerase
AL518_RS01955	COG3787	Belongs to the UPF0306 family
AL518_RS01965	COG2827	Endonuclease containing a URI domain
AL518_RS01970	COG3153	acetyltransferase
AL518_RS01975	COG3154	lipid carrier protein
AL518_RS01980	COG0826	peptidase U32
AL518_RS01985	COG0826	peptidase U32
AL518_RS01995	COG0814	amino acid
AL518_RS02000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL518_RS02005	COG0425	Belongs to the sulfur carrier protein TusA family
AL518_RS02010	COG2391	methyltransferase activity
AL518_RS02015	COG0513	Belongs to the DEAD box helicase family
AL518_RS02030	COG1185	polyribonucleotide nucleotidyltransferase activity
AL518_RS02040	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AL518_RS02045	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AL518_RS02055	COG0195	Participates in both transcription termination and antitermination
AL518_RS02075	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AL518_RS02080	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AL518_RS02085	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AL518_RS02100	COG1534	Rna-binding protein
AL518_RS02110	COG2027	D-alanyl-D-alanine carboxypeptidase
AL518_RS02115	COG0745	RESPONSE REGULATOR receiver
AL518_RS02120	COG0642	Histidine kinase
AL518_RS02125	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AL518_RS02130	COG0697	spore germination
AL518_RS02140	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AL518_RS02145	COG0142	geranyltranstransferase activity
AL518_RS02150	COG3423	Transcriptional regulator
AL518_RS02160	COG1438	arginine binding
AL518_RS02175	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AL518_RS02180	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AL518_RS02185	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AL518_RS02190	COG2105	PFAM AIG2 family protein
AL518_RS02200	COG0729	surface antigen
AL518_RS02210	COG1253	flavin adenine dinucleotide binding
AL518_RS02220	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AL518_RS02225	COG1218	3'(2'),5'-bisphosphate nucleotidase
AL518_RS02230	COG0737	Belongs to the 5'-nucleotidase family
AL518_RS02240	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
AL518_RS02245	COG0545	Peptidyl-prolyl cis-trans isomerase
AL518_RS02250	COG3061	Opacity-associated protein A
AL518_RS02260	COG0359	binds to the 23S rRNA
AL518_RS02265	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AL518_RS02275	COG0360	Binds together with S18 to 16S ribosomal RNA
AL518_RS02285	COG1073	alpha beta
AL518_RS02300	COG1960	acyl-CoA dehydrogenase activity
AL518_RS02305	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL518_RS02310	COG0557	exoribonuclease II activity
AL518_RS02315	COG1959	2 iron, 2 sulfur cluster binding
AL518_RS02325	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AL518_RS02330	COG0330	HflC and HflK could
AL518_RS02335	COG0330	HflC and HflK could
AL518_RS02340	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AL518_RS02345	COG1923	regulation of RNA biosynthetic process
AL518_RS02350	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AL518_RS02355	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AL518_RS02360	COG0860	N-Acetylmuramoyl-L-alanine amidase
AL518_RS02365	COG0802	atpase or kinase
AL518_RS02370	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AL518_RS02370	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AL518_RS02375	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AL518_RS02395	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AL518_RS02410	COG3264	Mechanosensitive ion channel
AL518_RS02410	COG1511	domain protein
AL518_RS02420	COG1053	succinate dehydrogenase
AL518_RS02425	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AL518_RS02430	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
AL518_RS02450	COG5510	response to toxic substance
AL518_RS02455	COG5510	response to toxic substance
AL518_RS02470	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AL518_RS02475	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AL518_RS02485	COG0762	integral membrane protein
AL518_RS02490	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AL518_RS02495	COG2805	Type II/IV secretion system protein
AL518_RS02500	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AL518_RS02505	COG1678	Uncharacterized ACR, COG1678
AL518_RS02510	COG0189	ligase activity
AL518_RS02515	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AL518_RS02520	COG2356	endonuclease I
AL518_RS02525	COG3091	SprT-like family
AL518_RS02540	COG0531	amino acid
AL518_RS02550	COG0754	glutathionylspermidine amidase activity
AL518_RS02555	COG5463	Belongs to the UPF0441 family
AL518_RS02565	COG2376	Dihydroxyacetone kinase
AL518_RS02570	COG1461	Dihydroxyacetone kinase
AL518_RS02585	COG2211	Major facilitator Superfamily
AL518_RS02595	COG2207	Transcriptional regulator
AL518_RS02600	COG1280	lysine exporter protein (LysE YggA)
AL518_RS02615	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AL518_RS02625	COG1027	Aspartate ammonia-lyase
AL518_RS02630	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AL518_RS02640	COG4232	protein-disulfide reductase activity
AL518_RS02645	COG1309	transcriptional regulator
AL518_RS02665	COG0456	acetyltransferase
AL518_RS02670	COG0318	PFAM AMP-dependent synthetase and ligase
AL518_RS02675	COG1090	epimerase
AL518_RS02680	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AL518_RS02685	COG0156	8-amino-7-oxononanoate synthase activity
AL518_RS02695	COG0795	lipopolysaccharide-transporting ATPase activity
AL518_RS02700	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AL518_RS02710	COG2244	polysaccharide biosynthetic process
AL518_RS02715	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AL518_RS02720	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AL518_RS02725	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AL518_RS02730	COG0306	phosphate transporter
AL518_RS02735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL518_RS02740	COG1271	oxidase subunit
AL518_RS02745	COG1294	oxidase, subunit
AL518_RS02760	COG3781	membrane
AL518_RS02770	COG2223	nitrite transmembrane transporter activity
AL518_RS02775	COG3247	response to pH
AL518_RS02780	COG1454	alcohol dehydrogenase
AL518_RS02785	COG0235	Class ii aldolase
AL518_RS02790	COG0738	Major facilitator superfamily
AL518_RS02800	COG1070	Carbohydrate kinase
AL518_RS02810	COG1349	DNA-binding transcription factor activity
AL518_RS02815	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AL518_RS02825	COG2211	Major facilitator Superfamily
AL518_RS02830	COG1501	Belongs to the glycosyl hydrolase 31 family
AL518_RS02855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL518_RS02860	COG1349	DNA-binding transcription factor activity
AL518_RS02875	COG2066	Belongs to the glutaminase family
AL518_RS02930	COG1982	Orn Lys Arg decarboxylase major
AL518_RS02935	COG0531	amino acid
AL518_RS02950	COG0741	lytic transglycosylase activity
AL518_RS02955	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AL518_RS02960	COG1194	a g-specific adenine glycosylase
AL518_RS02970	COG3171	Protein conserved in bacteria
AL518_RS02980	COG2207	Transcriptional regulator
AL518_RS02985	COG1979	alcohol dehydrogenase
AL518_RS03015	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AL518_RS03020	COG1309	transcriptional regulator
AL518_RS03030	COG0735	belongs to the Fur family
AL518_RS03035	COG3237	CsbD-like
AL518_RS03040	COG0534	Mate efflux family protein
AL518_RS03050	COG4565	transcriptional regulatory protein
AL518_RS03055	COG3290	protein histidine kinase activity
AL518_RS03060	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
AL518_RS03070	COG2301	Belongs to the HpcH HpaI aldolase family
AL518_RS03075	COG3051	citrate lyase alpha subunit
AL518_RS03090	COG0471	metal ion transport
AL518_RS03095	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AL518_RS03110	COG3161	chorismate lyase activity
AL518_RS03120	COG4580	involved in the transport of maltose and maltodextrins
AL518_RS03130	COG2182	Extracellular solute-binding protein
AL518_RS03135	COG1175	transmembrane transport
AL518_RS03140	COG3833	ABC-type maltose transport systems, permease component
AL518_RS03150	COG1301	dicarboxylic acid transport
AL518_RS03155	COG0166	Belongs to the GPI family
AL518_RS03165	COG0527	aspartate kinase activity
AL518_RS03175	COG0646	methionine synthase
AL518_RS03175	COG1410	methionine synthase
AL518_RS03185	COG0243	molybdopterin cofactor binding
AL518_RS03200	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AL518_RS03205	COG2222	sugar isomerase
AL518_RS03210	COG2188	Transcriptional regulator
AL518_RS03215	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL518_RS03220	COG3715	PTS system
AL518_RS03225	COG3716	PTS system mannose fructose sorbose family IID component
AL518_RS03240	COG1653	transport
AL518_RS03260	COG3150	esterase
AL518_RS03265	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AL518_RS03270	COG3151	Protein conserved in bacteria
AL518_RS03275	COG0494	nUDIX hydrolase
AL518_RS03280	COG1538	Outer membrane efflux protein
AL518_RS03295	COG1301	dicarboxylic acid transport
AL518_RS03300	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL518_RS03305	COG3162	membrane
AL518_RS03310	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL518_RS03355	COG0151	Belongs to the GarS family
AL518_RS03370	COG3068	Protein conserved in bacteria
AL518_RS03375	COG1515	deoxyribonuclease V activity
AL518_RS03380	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AL518_RS03385	COG2816	NAD+ diphosphatase activity
AL518_RS03390	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
AL518_RS03395	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AL518_RS03400	COG0352	thiamine-phosphate diphosphorylase activity
AL518_RS03405	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AL518_RS03410	COG2104	thiamine diphosphate biosynthetic process
AL518_RS03415	COG2022	thiamine diphosphate biosynthetic process
AL518_RS03435	COG0222	ribosome binding
AL518_RS03440	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AL518_RS03455	COG0250	Participates in transcription elongation, termination and antitermination
AL518_RS03495	COG1072	(Pantothenic acid kinase))
AL518_RS03505	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AL518_RS03510	COG4607	ABC-type enterochelin transport system periplasmic component
AL518_RS03535	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
AL518_RS03540	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AL518_RS03545	COG1739	Uncharacterized protein family UPF0029
AL518_RS03555	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL518_RS03555	COG1024	Enoyl-CoA hydratase
AL518_RS03560	COG0183	Belongs to the thiolase family
AL518_RS03595	COG0805	protein transport
AL518_RS03600	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AL518_RS03610	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AL518_RS03625	COG1322	Protein conserved in bacteria
AL518_RS03630	COG0586	Pfam SNARE associated Golgi protein
AL518_RS03635	COG1966	Carbon starvation protein
AL518_RS03640	COG2365	Tyrosine phosphatase family
AL518_RS03645	COG0412	Dienelactone hydrolase
AL518_RS03660	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL518_RS03660	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL518_RS03660	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AL518_RS03665	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL518_RS03670	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL518_RS03675	COG1882	Formate acetyltransferase
AL518_RS03680	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AL518_RS03685	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL518_RS03690	COG2207	Transcriptional regulator
AL518_RS03700	COG0583	DNA-binding transcription factor activity
AL518_RS03705	COG0697	spore germination
AL518_RS03730	COG1741	Belongs to the pirin family
AL518_RS03745	COG2723	6-phospho-beta-galactosidase activity
AL518_RS03750	COG1609	Transcriptional regulator
AL518_RS03755	COG1609	Transcriptional regulator
AL518_RS03760	COG3265	gluconokinase activity
AL518_RS03765	COG2610	gluconate transmembrane transporter activity
AL518_RS03780	COG1280	lysine exporter protein (LysE YggA)
AL518_RS03785	COG5002	protein histidine kinase activity
AL518_RS03790	COG0745	RESPONSE REGULATOR receiver
AL518_RS03805	COG0339	signal peptide processing
AL518_RS03810	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AL518_RS03820	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
AL518_RS03825	COG2050	protein possibly involved in aromatic compounds catabolism
AL518_RS03845	COG0210	DNA helicase
AL518_RS03850	COG1011	Hydrolase
AL518_RS03860	COG3159	Protein conserved in bacteria
AL518_RS03870	COG5567	small periplasmic lipoprotein
AL518_RS03875	COG1965	Belongs to the frataxin family
AL518_RS03885	COG3072	Adenylate cyclase
AL518_RS03895	COG1587	Uroporphyrinogen-III synthase
AL518_RS03900	COG2959	enzyme of heme biosynthesis
AL518_RS03905	COG3071	HemY protein
AL518_RS03945	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AL518_RS03950	COG2244	polysaccharide biosynthetic process
AL518_RS03955	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AL518_RS03960	COG0456	acetyltransferase
AL518_RS03965	COG1088	dTDP-glucose 4,6-dehydratase activity
AL518_RS03970	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AL518_RS03975	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AL518_RS03980	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
AL518_RS03985	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AL518_RS03990	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AL518_RS03995	COG3118	belongs to the thioredoxin family
AL518_RS04005	COG0248	Ppx GppA phosphatase
AL518_RS04010	COG0210	DNA helicase
AL518_RS04050	COG0129	dihydroxy-acid dehydratase activity
AL518_RS04060	COG3978	acetolactate synthase activity
AL518_RS04075	COG2814	Major facilitator Superfamily
AL518_RS04085	COG3085	chromosome segregation
AL518_RS04090	COG0583	DNA-binding transcription factor activity
AL518_RS04130	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AL518_RS04140	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AL518_RS04155	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL518_RS04165	COG0678	peroxiredoxin activity
AL518_RS04165	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AL518_RS04170	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL518_RS04175	COG0165	Argininosuccinate lyase
AL518_RS04190	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AL518_RS04195	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL518_RS04200	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AL518_RS04205	COG2194	sulfuric ester hydrolase activity
AL518_RS04210	COG0254	rRNA binding
AL518_RS04215	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AL518_RS04220	COG1609	Transcriptional regulator
AL518_RS04225	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AL518_RS04230	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AL518_RS04235	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AL518_RS04240	COG1575	Belongs to the MenA family. Type 1 subfamily
AL518_RS04245	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AL518_RS04250	COG3074	FtsZ-dependent cytokinesis
AL518_RS04255	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AL518_RS04265	COG1494	fructose-1,6-bisphosphatase
AL518_RS04270	COG2814	Major facilitator Superfamily
AL518_RS04285	COG3152	Membrane
AL518_RS04295	COG0149	triose-phosphate isomerase activity
AL518_RS04300	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AL518_RS04310	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AL518_RS04315	COG1368	sulfuric ester hydrolase activity
AL518_RS04320	COG3678	ATP-independent chaperone mediated protein folding
AL518_RS04325	COG0745	RESPONSE REGULATOR receiver
AL518_RS04330	COG2205	protein histidine kinase activity
AL518_RS04335	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AL518_RS04340	COG1045	serine acetyltransferase
AL518_RS04345	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AL518_RS04355	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AL518_RS04360	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AL518_RS04365	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AL518_RS04370	COG4942	peptidase
AL518_RS04375	COG2861	carbohydrate metabolic process
AL518_RS04380	COG2194	sulfuric ester hydrolase activity
AL518_RS04390	COG0156	8-amino-7-oxononanoate synthase activity
AL518_RS04400	COG0859	PFAM glycosyl transferase family 9
AL518_RS04405	COG0859	PFAM glycosyl transferase family 9
AL518_RS04415	COG0859	PFAM glycosyl transferase family 9
AL518_RS04425	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AL518_RS04430	COG1442	glycosyl transferase family 8
AL518_RS04440	COG0438	transferase activity, transferring glycosyl groups
AL518_RS04445	COG0859	PFAM glycosyl transferase family 9
AL518_RS04450	COG1519	Transferase
AL518_RS04455	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AL518_RS04460	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AL518_RS04470	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AL518_RS04475	COG2003	Belongs to the UPF0758 family
AL518_RS04480	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AL518_RS04485	COG0756	dUTP diphosphatase activity
AL518_RS04490	COG1309	transcriptional regulator
AL518_RS04505	COG1561	YicC-like family, N-terminal region
AL518_RS04520	COG2084	Dehydrogenase
AL518_RS04525	COG0583	DNA-binding transcription factor activity
AL518_RS04530	COG2860	membrane
AL518_RS04540	COG0194	GDP metabolic process
AL518_RS04550	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AL518_RS04555	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL518_RS04560	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AL518_RS04565	COG0786	glutamate:sodium symporter activity
AL518_RS04570	COG2233	PERMEase
AL518_RS04575	COG2982	Protein involved in outer membrane biogenesis
AL518_RS04590	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AL518_RS04600	COG1609	Transcriptional regulator
AL518_RS04605	COG2885	chlorophyll binding
AL518_RS04615	COG0456	acetyltransferase
AL518_RS04620	COG2818	Glycosylase
AL518_RS04625	COG5571	outer membrane autotransporter
AL518_RS04645	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL518_RS04645	COG2213	PTS system mannitol-specific
AL518_RS04650	COG0246	Mannitol dehydrogenase
AL518_RS04655	COG3722	fumarate hydratase activity
AL518_RS04665	COG3977	Valine--pyruvate aminotransferase
AL518_RS04675	COG0071	Belongs to the small heat shock protein (HSP20) family
AL518_RS04680	COG5645	(Lipo)protein
AL518_RS04685	COG0823	Involved in the tonB-independent uptake of proteins
AL518_RS04690	COG2271	Major facilitator Superfamily
AL518_RS04695	COG4948	Mandelate Racemase Muconate Lactonizing
AL518_RS04700	COG0800	Aldolase
AL518_RS04705	COG3734	2-keto-3-deoxy-galactonokinase
AL518_RS04710	COG2186	Transcriptional regulator
AL518_RS04725	COG0561	phosphatase activity
AL518_RS04735	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AL518_RS04740	COG0592	DNA-directed DNA polymerase activity
AL518_RS04750	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AL518_RS04775	COG0398	Pfam SNARE associated Golgi protein
AL518_RS04785	COG0431	NADPH-dependent FMN reductase
AL518_RS04790	COG2252	PERMEase
AL518_RS04800	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL518_RS04805	COG0765	amino acid transport
AL518_RS04810	COG0765	amino acid transport
AL518_RS04815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL518_RS04820	COG0704	Plays a role in the regulation of phosphate uptake
AL518_RS04830	COG0581	inorganic phosphate transmembrane transporter activity
AL518_RS04835	COG0573	inorganic phosphate transmembrane transporter activity
AL518_RS04840	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AL518_RS04850	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AL518_RS04855	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AL518_RS04860	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AL518_RS04865	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AL518_RS04895	COG3312	ion transport
AL518_RS04900	COG0357	Ribosomal RNA small subunit methyltransferase G
AL518_RS04905	COG0445	tRNA wobble uridine modification
AL518_RS04910	COG0716	FMN binding
AL518_RS04915	COG1522	sequence-specific DNA binding
AL518_RS04935	COG3158	transport of potassium into the cell
AL518_RS04945	COG1129	ABC transporter
AL518_RS04950	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL518_RS04955	COG1879	ABC-type sugar transport system periplasmic component
AL518_RS04960	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL518_RS04965	COG1609	Transcriptional regulator
AL518_RS04970	COG0477	Major facilitator Superfamily
AL518_RS04975	COG2186	Transcriptional regulator
AL518_RS05025	COG1763	Mo-molybdopterin cofactor biosynthetic process
AL518_RS05030	COG0746	molybdenum cofactor guanylyltransferase activity
AL518_RS05035	COG3084	Protein conserved in bacteria
AL518_RS05040	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AL518_RS05045	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL518_RS05050	COG0204	Acyl-transferase
AL518_RS05055	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AL518_RS05055	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AL518_RS05060	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AL518_RS05065	COG3078	GTPase activator activity
AL518_RS05075	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AL518_RS05080	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL518_RS05085	COG2814	Major facilitator Superfamily
AL518_RS05090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL518_RS05100	COG3058	Necessary for formate dehydrogenase activity
AL518_RS05105	COG2864	formate dehydrogenase
AL518_RS05110	COG0437	4 iron, 4 sulfur cluster binding
AL518_RS05130	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AL518_RS05135	COG2258	MOSC domain
AL518_RS05140	COG0583	DNA-binding transcription factor activity
AL518_RS05145	COG2610	gluconate transmembrane transporter activity
AL518_RS05150	COG3048	D-serine ammonia-lyase activity
AL518_RS05155	COG3714	YhhN family
AL518_RS05170	COG3776	membrane
AL518_RS05175	COG0742	ribosomal rna small subunit methyltransferase
AL518_RS05180	COG0552	protein localization to endoplasmic reticulum
AL518_RS05180	COG0552	protein localization to endoplasmic reticulum
AL518_RS05185	COG2884	Cell division ATP-binding protein ftsE
AL518_RS05190	COG2177	Part of the ABC transporter FtsEX involved in
AL518_RS05200	COG3835	regulator
AL518_RS05205	COG2610	gluconate transmembrane transporter activity
AL518_RS05210	COG1929	Belongs to the glycerate kinase type-1 family
AL518_RS05215	COG0456	acetyltransferase
AL518_RS05230	COG4177	L-phenylalanine transmembrane transporter activity
AL518_RS05245	COG1653	transport
AL518_RS05250	COG1175	transmembrane transport
AL518_RS05255	COG0395	ABC-type sugar transport system, permease component
AL518_RS05265	COG0584	glycerophosphoryl diester phosphodiesterase
AL518_RS05285	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AL518_RS05290	COG0705	Rhomboid family
AL518_RS05295	COG1349	DNA-binding transcription factor activity
AL518_RS05305	COG2944	sequence-specific DNA binding
AL518_RS05310	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AL518_RS05325	COG0058	SHG alpha-glucan phosphorylase activity
AL518_RS05335	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AL518_RS05340	COG1523	belongs to the glycosyl hydrolase 13 family
AL518_RS05350	COG1640	4-alpha-glucanotransferase
AL518_RS05355	COG0058	SHG alpha-glucan phosphorylase activity
AL518_RS05360	COG2909	trisaccharide binding
AL518_RS05370	COG0460	homoserine dehydrogenase
AL518_RS05370	COG0527	aspartate kinase activity
AL518_RS05375	COG0626	cystathionine gamma-synthase activity
AL518_RS05380	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
AL518_RS05390	COG1070	Carbohydrate kinase
AL518_RS05400	COG0477	Major facilitator Superfamily
AL518_RS05400	COG2814	Major facilitator Superfamily
AL518_RS05405	COG1609	Transcriptional regulator
AL518_RS05405	COG2207	Transcriptional regulator
AL518_RS05410	COG3274	enterobacterial common antigen metabolic process
AL518_RS05420	COG0456	acetyltransferase
AL518_RS05425	COG1490	D-aminoacyl-tRNA deacylase activity
AL518_RS05430	COG1295	ribonuclease BN
AL518_RS05435	COG1011	Hydrolase
AL518_RS05440	COG0840	transmembrane signaling receptor activity
AL518_RS05465	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL518_RS05470	COG3642	lipopolysaccharide core region biosynthetic process
AL518_RS05480	COG0590	tRNA wobble adenosine to inosine editing
AL518_RS05485	COG2807	transmembrane transport
AL518_RS05490	COG1501	Belongs to the glycosyl hydrolase 31 family
AL518_RS05495	COG2211	Major facilitator Superfamily
AL518_RS05525	COG0835	chemotaxis
AL518_RS05525	COG0784	Response regulator, receiver
AL518_RS05530	COG1028	Short-chain dehydrogenase reductase Sdr
AL518_RS05535	COG0662	Cupin 2, conserved barrel domain protein
AL518_RS05535	COG2207	Transcriptional regulator
AL518_RS05540	COG2094	Belongs to the DNA glycosylase MPG family
AL518_RS05550	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AL518_RS05555	COG0814	amino acid
AL518_RS05560	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AL518_RS05565	COG1882	Formate acetyltransferase
AL518_RS05585	COG1982	Orn Lys Arg decarboxylase major
AL518_RS05590	COG2207	Transcriptional regulator
AL518_RS05595	COG0531	amino acid
AL518_RS05605	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AL518_RS05615	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AL518_RS05620	COG2194	sulfuric ester hydrolase activity
AL518_RS05630	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AL518_RS05635	COG0747	negative chemotaxis
AL518_RS05640	COG0601	transmembrane transport
AL518_RS05645	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL518_RS05650	COG0444	Belongs to the ABC transporter superfamily
AL518_RS05655	COG4608	Belongs to the ABC transporter superfamily
AL518_RS05660	COG2194	sulfuric ester hydrolase activity
AL518_RS05685	COG1215	transferase activity, transferring glycosyl groups
AL518_RS05690	COG1215	transferase activity, transferring glycosyl groups
AL518_RS05695	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AL518_RS05700	COG3118	belongs to the thioredoxin family
AL518_RS05700	COG0457	Tetratricopeptide repeat
AL518_RS05705	COG2199	diguanylate cyclase activity
AL518_RS05705	COG2200	EAL domain
AL518_RS05715	COG0612	Peptidase, M16
AL518_RS05720	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL518_RS05725	COG1942	4-Oxalocrotonate Tautomerase
AL518_RS05730	COG2200	EAL domain
AL518_RS05735	COG2982	Protein involved in outer membrane biogenesis
AL518_RS05745	COG2261	transglycosylase associated protein
AL518_RS05760	COG2814	Major facilitator Superfamily
AL518_RS05765	COG0583	DNA-binding transcription factor activity
AL518_RS05770	COG1295	ribonuclease BN
AL518_RS05775	COG0583	DNA-binding transcription factor activity
AL518_RS05790	COG0004	ammonium transporteR
AL518_RS05800	COG0076	glutamate decarboxylase activity
AL518_RS05805	COG0531	amino acid
AL518_RS05815	COG0531	amino acid
AL518_RS05820	COG2095	MarC family integral membrane protein
AL518_RS05825	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL518_RS05855	COG0589	response to stress
AL518_RS05865	COG0733	neurotransmitter:sodium symporter activity
AL518_RS05870	COG0306	phosphate transporter
AL518_RS05875	COG2081	HI0933 family
AL518_RS05910	COG3121	Chaperone
AL518_RS05925	COG1247	-acetyltransferase
AL518_RS05930	COG3275	phosphorelay sensor kinase activity
AL518_RS05935	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AL518_RS05940	COG2267	carboxylic ester hydrolase activity
AL518_RS05945	COG0561	phosphatase activity
AL518_RS05950	COG3477	response to acidic pH
AL518_RS06000	COG1040	competence protein
AL518_RS06005	COG2267	carboxylic ester hydrolase activity
AL518_RS06015	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AL518_RS06020	COG1918	ferrous iron import across plasma membrane
AL518_RS06025	COG2183	response to ionizing radiation
AL518_RS06030	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AL518_RS06050	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AL518_RS06055	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AL518_RS06060	COG1011	Hydrolase
AL518_RS06070	COG0494	nUDIX hydrolase
AL518_RS06075	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AL518_RS06100	COG4796	Type ii and iii secretion system protein
AL518_RS06105	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AL518_RS06125	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AL518_RS06130	COG0546	phosphoglycolate phosphatase activity
AL518_RS06135	COG0180	Tryptophanyl-tRNA synthetase
AL518_RS06145	COG1648	precorrin-2 dehydrogenase activity
AL518_RS06145	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AL518_RS06150	COG2116	formate transmembrane transporter activity
AL518_RS06160	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL518_RS06165	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AL518_RS06170	COG0402	S-adenosylhomocysteine deaminase activity
AL518_RS06180	COG1609	Transcriptional regulator
AL518_RS06185	COG1486	melibiose metabolic process
AL518_RS06195	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AL518_RS06205	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AL518_RS06215	COG0433	COG0433 Predicted ATPase
AL518_RS06230	COG1289	transmembrane transporter activity
AL518_RS06235	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL518_RS06240	COG1765	OsmC-like protein
AL518_RS06245	COG3954	Phosphoribulokinase
AL518_RS06250	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AL518_RS06255	COG3089	Belongs to the UPF0270 family
AL518_RS06260	COG0429	hydrolase of the alpha beta-hydrolase fold
AL518_RS06270	COG4521	taurine ABC transporter
AL518_RS06280	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL518_RS06285	COG2175	clavaminate synthase activity
AL518_RS06290	COG0488	(ABC) transporter
AL518_RS06295	COG2249	NAD(P)H dehydrogenase (quinone) activity
AL518_RS06305	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AL518_RS06310	COG1047	Peptidyl-prolyl cis-trans
AL518_RS06315	COG2900	Belongs to the SlyX family
AL518_RS06320	COG0545	Peptidyl-prolyl cis-trans isomerase
AL518_RS06325	COG2964	Protein conserved in bacteria
AL518_RS06330	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AL518_RS06340	COG2168	tRNA wobble position uridine thiolation
AL518_RS06345	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AL518_RS06350	COG0049	tRNA binding
AL518_RS06355	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AL518_RS06375	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AL518_RS06380	COG0051	transcription antitermination factor activity, RNA binding
AL518_RS06385	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AL518_RS06390	COG0088	Forms part of the polypeptide exit tunnel
AL518_RS06405	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AL518_RS06410	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AL518_RS06420	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AL518_RS06450	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AL518_RS06460	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AL518_RS06470	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AL518_RS06475	COG1841	ribosomal large subunit assembly
AL518_RS06485	COG0201	protein transport
AL518_RS06490	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AL518_RS06495	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AL518_RS06515	COG0203	ribosomal protein L17
AL518_RS06525	COG0789	Transcriptional regulator
AL518_RS06530	COG3036	rescue of stalled ribosome
AL518_RS06535	COG1970	mechanosensitive ion channel activity
AL518_RS06540	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AL518_RS06545	COG0569	domain protein
AL518_RS06550	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AL518_RS06550	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AL518_RS06555	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AL518_RS06565	COG0758	DNA mediated transformation
AL518_RS06570	COG2922	Belongs to the Smg family
AL518_RS06575	COG0551	DNA topoisomerase type I activity
AL518_RS06580	COG0009	L-threonylcarbamoyladenylate synthase
AL518_RS06595	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AL518_RS06620	COG0477	Major facilitator Superfamily
AL518_RS06625	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AL518_RS06630	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AL518_RS06640	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
AL518_RS06655	COG0656	L-ascorbic acid biosynthetic process
AL518_RS06660	COG1448	Aminotransferase
AL518_RS06665	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL518_RS06670	COG2313	pseudouridylate synthase activity
AL518_RS06675	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AL518_RS06685	COG0432	Pfam Uncharacterised protein family UPF0047
AL518_RS06690	COG2315	Protein conserved in bacteria
AL518_RS06695	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AL518_RS06700	COG0629	single-stranded DNA binding
AL518_RS06710	COG3829	transcription factor binding
AL518_RS06720	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AL518_RS06725	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AL518_RS06730	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL518_RS06740	COG0549	Belongs to the carbamate kinase family
AL518_RS06745	COG3608	succinylglutamate desuccinylase aspartoacylase
AL518_RS06745	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AL518_RS06750	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AL518_RS06755	COG2068	MobA-Related Protein
AL518_RS06760	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL518_RS06760	COG0493	'glutamate synthase
AL518_RS06765	COG0402	S-adenosylhomocysteine deaminase activity
AL518_RS06770	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AL518_RS06775	COG2080	2 iron, 2 sulfur cluster binding
AL518_RS06775	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AL518_RS06780	COG2233	PERMEase
AL518_RS06785	COG0402	S-adenosylhomocysteine deaminase activity
AL518_RS06790	COG2252	PERMEase
AL518_RS06795	COG0025	NhaP-type Na H and K H
AL518_RS06800	COG0583	DNA-binding transcription factor activity
AL518_RS06825	COG1737	Transcriptional regulator
AL518_RS06830	COG2190	(PTS) system
AL518_RS06830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL518_RS06830	COG1263	PTS System
AL518_RS06835	COG2723	6-phospho-beta-galactosidase activity
AL518_RS06845	COG1028	Short-chain dehydrogenase reductase Sdr
AL518_RS06850	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL518_RS06855	COG0129	dihydroxy-acid dehydratase activity
AL518_RS06860	COG2271	Major facilitator Superfamily
AL518_RS06865	COG2814	Major facilitator Superfamily
AL518_RS06875	COG0800	Aldolase
AL518_RS06880	COG3734	2-keto-3-deoxy-galactonokinase
AL518_RS06885	COG2186	Transcriptional regulator
AL518_RS06910	COG2264	protein methyltransferase activity
AL518_RS06915	COG4145	pantothenate transmembrane transporter activity
AL518_RS06920	COG3924	membrane
AL518_RS06925	COG0439	Biotin carboxylase
AL518_RS06930	COG0511	ligase activity, forming carbon-carbon bonds
AL518_RS06935	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AL518_RS06940	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AL518_RS06945	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AL518_RS06950	COG0604	alcohol dehydrogenase
AL518_RS06955	COG2200	EAL domain
AL518_RS06955	COG2199	diguanylate cyclase activity
AL518_RS06960	COG1077	Cell shape determining protein MreB Mrl
AL518_RS06965	COG1792	Involved in formation and maintenance of cell shape
AL518_RS06970	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AL518_RS06975	COG0424	maF-like protein
AL518_RS06985	COG3164	Protein of unknown function
AL518_RS06990	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AL518_RS06995	COG0312	modulator of DNA gyrase
AL518_RS07000	COG0583	DNA-binding transcription factor activity
AL518_RS07010	COG1566	PFAM secretion protein HlyD family protein
AL518_RS07015	COG1289	transmembrane transporter activity
AL518_RS07020	COG0540	Belongs to the ATCase OTCase family
AL518_RS07035	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AL518_RS07040	COG1012	belongs to the aldehyde dehydrogenase family
AL518_RS07045	COG3276	selenocysteine insertion sequence binding
AL518_RS07055	COG0625	glutathione transferase activity
AL518_RS07065	COG0584	glycerophosphoryl diester phosphodiesterase
AL518_RS07070	COG2271	Major facilitator Superfamily
AL518_RS07075	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AL518_RS07085	COG0247	lactate metabolic process
AL518_RS07095	COG1263	PTS System
AL518_RS07095	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL518_RS07100	COG1486	melibiose metabolic process
AL518_RS07110	COG0738	Major facilitator superfamily
AL518_RS07115	COG1263	PTS System
AL518_RS07115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL518_RS07120	COG0366	Alpha amylase catalytic
AL518_RS07125	COG2731	YhcH YjgK YiaL family protein
AL518_RS07130	COG0583	DNA-binding transcription factor activity
AL518_RS07140	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AL518_RS07145	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AL518_RS07150	COG2271	Major facilitator Superfamily
AL518_RS07155	COG0549	Belongs to the carbamate kinase family
AL518_RS07175	COG3829	transcription factor binding
AL518_RS07185	COG0531	amino acid
AL518_RS07190	COG3457	Alanine racemase
AL518_RS07195	COG0833	amino acid
AL518_RS07200	COG0456	acetyltransferase
AL518_RS07205	COG3852	Histidine kinase
AL518_RS07210	COG2204	response regulator
AL518_RS07215	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AL518_RS07220	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AL518_RS07225	COG2031	fatty acid transporter
AL518_RS07230	COG0183	Belongs to the thiolase family
AL518_RS07240	COG2927	DNA polymerase III (CHI subunit)
AL518_RS07250	COG0795	lipopolysaccharide-transporting ATPase activity
AL518_RS07255	COG0795	lipopolysaccharide-transporting ATPase activity
AL518_RS07260	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AL518_RS07265	COG1376	ErfK ybiS ycfS ynhG family protein
AL518_RS07285	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AL518_RS07305	COG1401	restriction endodeoxyribonuclease activity
AL518_RS07320	COG0754	glutathionylspermidine amidase activity
AL518_RS07325	COG2850	peptidyl-arginine hydroxylation
AL518_RS07330	COG1988	membrane-bound metal-dependent
AL518_RS07345	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AL518_RS07350	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AL518_RS07365	COG0583	DNA-binding transcription factor activity
AL518_RS07370	COG2258	MOSC domain
AL518_RS07380	COG0157	Belongs to the NadC ModD family
AL518_RS07385	COG0500	methyltransferase
AL518_RS07390	COG1120	ATPase activity
AL518_RS07395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL518_RS07400	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL518_RS07415	COG2271	Major facilitator Superfamily
AL518_RS07420	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AL518_RS07480	COG2207	Transcriptional regulator
AL518_RS07490	COG1012	belongs to the aldehyde dehydrogenase family
AL518_RS07495	COG0840	transmembrane signaling receptor activity
AL518_RS07515	COG3069	C4-dicarboxylate transmembrane transporter activity
AL518_RS07520	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AL518_RS07525	COG0583	DNA-binding transcription factor activity
AL518_RS07560	COG1414	Transcriptional regulator
AL518_RS07570	COG2731	YhcH YjgK YiaL family protein
AL518_RS07585	COG1070	Carbohydrate kinase
AL518_RS07590	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AL518_RS07595	COG3623	hexulose-6-phosphate isomerase
AL518_RS07600	COG0235	Class ii aldolase
AL518_RS07605	COG0791	NLP P60 protein
AL518_RS07610	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AL518_RS07615	COG2723	6-phospho-beta-galactosidase activity
AL518_RS07625	COG0513	Belongs to the DEAD box helicase family
AL518_RS07640	COG2084	Dehydrogenase
AL518_RS07665	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL518_RS07675	COG1012	belongs to the aldehyde dehydrogenase family
AL518_RS07685	COG2732	(Barnase) inhibitor
AL518_RS07690	COG3028	Belongs to the UPF0307 family
AL518_RS07695	COG1598	PFAM Uncharacterised protein family UPF0150
AL518_RS07705	COG0312	modulator of DNA gyrase
AL518_RS07715	COG3783	Cytochrome b(562)
AL518_RS07725	COG1305	Transglutaminase-like
AL518_RS07730	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AL518_RS07760	COG3964	amidohydrolase
AL518_RS07775	COG3711	transcriptional antiterminator
AL518_RS07775	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL518_RS07785	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL518_RS07805	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AL518_RS07810	COG1137	ATPase activity
AL518_RS07815	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AL518_RS07820	COG3117	lipopolysaccharide transmembrane transporter activity
AL518_RS07825	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AL518_RS07830	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AL518_RS07830	COG0517	IMP dehydrogenase activity
AL518_RS07835	COG0530	calcium, potassium:sodium antiporter activity
AL518_RS07840	COG1127	ABC transporter
AL518_RS07845	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AL518_RS07850	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AL518_RS07855	COG2854	intermembrane phospholipid transfer
AL518_RS07860	COG3113	response to antibiotic
AL518_RS07865	COG5007	Belongs to the BolA IbaG family
AL518_RS07870	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AL518_RS07875	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL518_RS07880	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL518_RS07885	COG3105	Protein conserved in bacteria
AL518_RS07890	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AL518_RS07895	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AL518_RS07900	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AL518_RS07905	COG0625	glutathione transferase activity
AL518_RS07910	COG2969	positive regulation of protein catabolic process
AL518_RS07915	COG1737	Transcriptional regulator
AL518_RS07920	COG2731	YhcH YjgK YiaL family protein
AL518_RS07935	COG0493	'glutamate synthase
AL518_RS07940	COG0069	glutamate synthase activity
AL518_RS07940	COG0070	glutamate synthase
AL518_RS07940	COG0067	glutamate synthase
AL518_RS07945	COG1242	4 iron, 4 sulfur cluster binding
AL518_RS07955	COG0784	Response regulator, receiver
AL518_RS07955	COG2198	Histidine kinase
AL518_RS07955	COG5002	protein histidine kinase activity
AL518_RS07960	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AL518_RS07970	COG2823	Periplasmic or secreted lipoprotein
AL518_RS07975	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AL518_RS07980	COG0792	nuclease activity
AL518_RS07990	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AL518_RS08000	COG3726	membrane protein affecting hemolysin expression
AL518_RS08005	COG0560	Phosphoserine phosphatase
AL518_RS08010	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AL518_RS08020	COG3064	Membrane
AL518_RS08030	COG0604	alcohol dehydrogenase
AL518_RS08040	COG0488	(ABC) transporter
AL518_RS08045	COG1278	Cold shock
AL518_RS08055	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
AL518_RS08060	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
AL518_RS08065	COG0406	alpha-ribazole phosphatase activity
AL518_RS08070	COG3708	Transcriptional regulator
AL518_RS08070	COG2207	Transcriptional regulator
AL518_RS08075	COG3045	CreA protein
AL518_RS08080	COG0442	prolyl-tRNA aminoacylation
AL518_RS08085	COG1720	tRNA m6t6A37 methyltransferase activity
AL518_RS08095	COG1464	Belongs to the NlpA lipoprotein family
AL518_RS08110	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AL518_RS08135	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL518_RS08140	COG1042	CoA-binding domain protein
AL518_RS08140	COG0045	succinate-CoA ligase (ADP-forming) activity
AL518_RS08140	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL518_RS08145	COG3148	PFAM DTW domain containing protein
AL518_RS08150	COG3118	belongs to the thioredoxin family
AL518_RS08155	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL518_RS08160	COG0745	RESPONSE REGULATOR receiver
AL518_RS08165	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AL518_RS08190	COG3022	response to hydroperoxide
AL518_RS08195	COG1115	amino acid carrier protein
AL518_RS08215	COG0579	oxidoreductase
AL518_RS08220	COG1012	belongs to the aldehyde dehydrogenase family
AL518_RS08225	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL518_RS08230	COG1113	amino acid transport
AL518_RS08235	COG1802	Transcriptional regulator
AL518_RS08255	COG0521	Mo-molybdopterin cofactor biosynthetic process
AL518_RS08260	COG0477	Major facilitator Superfamily
AL518_RS08280	COG1584	GPR1 FUN34 yaaH family protein
AL518_RS08285	COG0443	Heat shock 70 kDa protein
AL518_RS08290	COG0484	heat shock protein binding
AL518_RS08295	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AL518_RS08300	COG0583	DNA-binding transcription factor activity
AL518_RS08310	COG0196	riboflavin kinase activity
AL518_RS08325	COG1047	Peptidyl-prolyl cis-trans
AL518_RS08330	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AL518_RS08340	COG2080	2 iron, 2 sulfur cluster binding
AL518_RS08345	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AL518_RS08350	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AL518_RS08355	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AL518_RS08360	COG0505	Belongs to the CarA family
AL518_RS08365	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AL518_RS08385	COG2966	Psort location CytoplasmicMembrane, score
AL518_RS08395	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AL518_RS08415	COG3539	Fimbrial protein
AL518_RS08475	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AL518_RS08485	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AL518_RS08490	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AL518_RS08500	COG1924	4 iron, 4 sulfur cluster binding
AL518_RS08505	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
AL518_RS08510	COG0564	pseudouridine synthase activity
AL518_RS08520	COG0417	DNA replication proofreading
AL518_RS08530	COG0586	Pfam SNARE associated Golgi protein
AL518_RS08540	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
AL518_RS08545	COG1178	ABC-type Fe3 transport system permease component
AL518_RS08550	COG4143	(ABC) transporter
AL518_RS08560	COG2814	Major facilitator Superfamily
AL518_RS08565	COG4650	regulator
AL518_RS08575	COG3541	Predicted nucleotidyltransferase
AL518_RS08580	COG0471	metal ion transport
AL518_RS08600	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AL518_RS08605	COG0473	3-isopropylmalate dehydrogenase activity
AL518_RS08615	COG0583	DNA-binding transcription factor activity
AL518_RS08620	COG1022	Amp-dependent synthetase and ligase
AL518_RS08625	COG0028	Belongs to the TPP enzyme family
AL518_RS08635	COG1609	Transcriptional regulator
AL518_RS08645	COG2001	Belongs to the MraZ family
AL518_RS08650	COG0275	rRNA processing
AL518_RS08655	COG3116	cell division
AL518_RS08660	COG0768	penicillin binding
AL518_RS08665	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AL518_RS08670	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AL518_RS08675	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AL518_RS08680	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AL518_RS08685	COG0772	Belongs to the SEDS family
AL518_RS08690	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AL518_RS08695	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AL518_RS08705	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AL518_RS08710	COG0849	cell division
AL518_RS08715	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AL518_RS08735	COG0494	nUDIX hydrolase
AL518_RS08740	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AL518_RS08745	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AL518_RS08755	COG0516	GMP reductase activity
AL518_RS08760	COG1459	type II secretion system
AL518_RS08765	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AL518_RS08770	COG4969	Belongs to the N-Me-Phe pilin family
AL518_RS08780	COG3023	N-Acetylmuramoyl-L-alanine amidase
AL518_RS08785	COG3725	Membrane protein required for beta-lactamase induction
AL518_RS08790	COG3940	Belongs to the glycosyl hydrolase 43 family
AL518_RS08795	COG2211	Major facilitator Superfamily
AL518_RS08800	COG1113	amino acid transport
AL518_RS08805	COG2186	Transcriptional regulator
AL518_RS08810	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AL518_RS08815	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL518_RS08820	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL518_RS08835	COG2304	oxidoreductase activity
AL518_RS08840	COG2979	Protein of unknown function (DUF533)
AL518_RS08855	COG2132	Multicopper oxidase
AL518_RS08860	COG0726	polysaccharide deacetylase
AL518_RS08865	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AL518_RS08880	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AL518_RS08905	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AL518_RS08910	COG1643	Atp-dependent helicase
AL518_RS08915	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AL518_RS08925	COG4774	siderophore transport
AL518_RS08930	COG1120	ATPase activity
AL518_RS08935	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL518_RS08940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL518_RS08945	COG3416	Protein conserved in bacteria
AL518_RS08950	COG2234	aminopeptidase activity
AL518_RS08960	COG2895	sulfate adenylyltransferase (ATP) activity
AL518_RS08980	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AL518_RS08985	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AL518_RS09010	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AL518_RS09020	COG1074	ATP-dependent DNA helicase activity
AL518_RS09025	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AL518_RS09030	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AL518_RS09030	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AL518_RS09035	COG0860	N-Acetylmuramoyl-L-alanine amidase
AL518_RS09055	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AL518_RS09060	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AL518_RS09065	COG2166	iron-sulfur cluster assembly
AL518_RS09070	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AL518_RS09080	COG0583	DNA-binding transcription factor activity
AL518_RS09085	COG2363	Small membrane protein
AL518_RS09095	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AL518_RS09100	COG1611	Belongs to the LOG family
AL518_RS09115	COG3098	single-species biofilm formation
AL518_RS09145	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AL518_RS09170	COG0528	UMP kinase activity
AL518_RS09185	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AL518_RS09190	COG0575	Belongs to the CDS family
AL518_RS09195	COG0750	zinc metalloprotease
AL518_RS09205	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
AL518_RS09210	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL518_RS09215	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AL518_RS09220	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL518_RS09225	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL518_RS09245	COG0346	lactoylglutathione lyase activity
AL518_RS09250	COG3710	Transcriptional regulator
AL518_RS09255	COG0531	amino acid
AL518_RS09260	COG1982	Orn Lys Arg decarboxylase major
AL518_RS09280	COG4568	rho-dependent transcription termination
AL518_RS09300	COG3015	lipoprotein NlpE involved in copper resistance
AL518_RS09305	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL518_RS09310	COG0560	Phosphoserine phosphatase
AL518_RS09315	COG1335	isochorismatase
AL518_RS09325	COG0583	DNA-binding transcription factor activity
AL518_RS09330	COG1454	alcohol dehydrogenase
AL518_RS09335	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AL518_RS09345	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AL518_RS09360	COG2205	protein histidine kinase activity
AL518_RS09365	COG3170	Tfp pilus assembly protein FimV
AL518_RS09370	COG2204	response regulator
AL518_RS09375	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AL518_RS09375	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AL518_RS09380	COG0347	Belongs to the P(II) protein family
AL518_RS09390	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AL518_RS09395	COG0121	glutamine amidotransferase
AL518_RS09400	COG3034	peptidoglycan biosynthetic process
AL518_RS09410	COG1805	sodium ion transport
AL518_RS09415	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AL518_RS09420	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AL518_RS09425	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AL518_RS09430	COG2871	sodium ion transport
AL518_RS09435	COG1477	protein flavinylation
AL518_RS09440	COG2991	Protein conserved in bacteria
AL518_RS09450	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AL518_RS09455	COG2195	Cleaves the N-terminal amino acid of tripeptides
AL518_RS09465	COG1073	alpha beta
AL518_RS09475	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AL518_RS09480	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AL518_RS09485	COG2130	NADP-dependent
AL518_RS09520	COG0702	epimerase
AL518_RS09530	COG0667	Aldo Keto reductase
AL518_RS09535	COG0656	L-ascorbic acid biosynthetic process
AL518_RS09540	COG0583	DNA-binding transcription factor activity
AL518_RS09545	COG1064	alcohol dehydrogenase
AL518_RS09555	COG1028	Short-chain dehydrogenase reductase Sdr
AL518_RS09565	COG1064	alcohol dehydrogenase
AL518_RS09600	COG5002	protein histidine kinase activity
AL518_RS09610	COG0667	Aldo Keto reductase
AL518_RS09620	COG2814	Major facilitator Superfamily
AL518_RS09655	COG3596	GTP binding
AL518_RS09670	COG3710	Transcriptional regulator
AL518_RS09675	COG2200	EAL domain
AL518_RS09710	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AL518_RS09720	COG3153	acetyltransferase
AL518_RS09735	COG3706	GGDEF domain
AL518_RS09735	COG4251	negative regulation of phosphorylation
AL518_RS09735	COG5001	Diguanylate cyclase
AL518_RS09735	COG2203	Gaf domain
AL518_RS09745	COG1064	alcohol dehydrogenase
AL518_RS09750	COG1609	Transcriptional regulator
AL518_RS09755	COG2211	Major facilitator Superfamily
AL518_RS09760	COG1621	beta-fructofuranosidase activity
AL518_RS09770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL518_RS09775	COG0583	DNA-binding transcription factor activity
AL518_RS09795	COG0745	RESPONSE REGULATOR receiver
AL518_RS09805	COG2202	Pas domain
AL518_RS09805	COG2200	EAL domain
AL518_RS09805	COG2199	diguanylate cyclase activity
AL518_RS09815	COG3121	Chaperone
AL518_RS09825	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL518_RS09850	COG1289	transmembrane transporter activity
AL518_RS09855	COG1538	Outer membrane efflux protein
AL518_RS09860	COG1742	UPF0060 membrane protein
AL518_RS09870	COG1770	oligopeptidase
AL518_RS09885	COG0848	biopolymer transport protein
AL518_RS09900	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL518_RS09905	COG2368	4-hydroxyphenylacetate
AL518_RS09925	COG3971	2-oxopent-4-enoate hydratase activity
AL518_RS09930	COG1012	belongs to the aldehyde dehydrogenase family
AL518_RS09940	COG3384	dioxygenase
AL518_RS09945	COG1012	belongs to the aldehyde dehydrogenase family
AL518_RS09960	COG1846	Transcriptional regulator
AL518_RS09970	COG1278	Cold shock
AL518_RS09975	COG1560	Kdo2-lipid A biosynthetic process
AL518_RS09980	COG1011	Hydrolase
AL518_RS10010	COG0531	amino acid
AL518_RS10020	COG0443	Heat shock 70 kDa protein
AL518_RS10025	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AL518_RS10030	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AL518_RS10035	COG5001	Diguanylate cyclase
AL518_RS10035	COG5002	protein histidine kinase activity
AL518_RS10035	COG3447	MASE1 domain protein
AL518_RS10040	COG2239	Acts as a magnesium transporter
AL518_RS10050	COG2200	EAL domain
AL518_RS10070	COG0668	transmembrane transport
AL518_RS10075	COG0366	Alpha amylase catalytic
AL518_RS10080	COG0450	alkyl hydroperoxide reductase
AL518_RS10085	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
AL518_RS10090	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AL518_RS10095	COG0343	queuine tRNA-ribosyltransferase activity
AL518_RS10100	COG1862	Preprotein translocase
AL518_RS10110	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL518_RS10125	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL518_RS10125	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL518_RS10140	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AL518_RS10145	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AL518_RS10150	COG0667	Aldo Keto reductase
AL518_RS10160	COG0251	oxidation-reduction process
AL518_RS10175	COG0142	geranyltranstransferase activity
AL518_RS10190	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
AL518_RS10195	COG0693	protein deglycase activity
AL518_RS10200	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AL518_RS10210	COG2814	Major facilitator Superfamily
AL518_RS10215	COG0109	protoheme IX farnesyltransferase activity
AL518_RS10220	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AL518_RS10225	COG1845	cytochrome c oxidase, subunit III
AL518_RS10230	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AL518_RS10235	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AL518_RS10240	COG2223	nitrite transmembrane transporter activity
AL518_RS10245	COG3056	Lipoprotein
AL518_RS10250	COG1609	Transcriptional regulator
AL518_RS10255	COG0673	inositol 2-dehydrogenase activity
AL518_RS10265	COG0673	inositol 2-dehydrogenase activity
AL518_RS10270	COG2211	Major facilitator Superfamily
AL518_RS10280	COG0271	Belongs to the BolA IbaG family
AL518_RS10295	COG0740	serine-type endopeptidase activity
AL518_RS10300	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AL518_RS10305	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AL518_RS10310	COG0776	regulation of translation
AL518_RS10315	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL518_RS10320	COG1555	photosystem II stabilization
AL518_RS10325	COG0824	Thioesterase
AL518_RS10335	COG4533	DNA binding
AL518_RS10345	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AL518_RS10350	COG1522	sequence-specific DNA binding
AL518_RS10355	COG1132	(ABC) transporter
AL518_RS10360	COG1132	(ABC) transporter
AL518_RS10365	COG0347	Belongs to the P(II) protein family
AL518_RS10370	COG0004	ammonium transporteR
AL518_RS10375	COG1946	Acyl-CoA thioesterase
AL518_RS10380	COG3126	Type III secretion system lipoprotein chaperone (YscW)
AL518_RS10385	COG3695	enzyme binding
AL518_RS10405	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AL518_RS10415	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL518_RS10420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL518_RS10425	COG1309	transcriptional regulator
AL518_RS10430	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AL518_RS10435	COG1196	nuclear chromosome segregation
AL518_RS10435	COG3264	Mechanosensitive ion channel
AL518_RS10445	COG2261	transglycosylase associated protein
AL518_RS10455	COG2832	Protein of unknown function (DUF454)
AL518_RS10460	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AL518_RS10470	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AL518_RS10485	COG0531	amino acid
AL518_RS10500	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AL518_RS10505	COG0563	adenylate kinase activity
AL518_RS10510	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AL518_RS10515	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL518_RS10520	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AL518_RS10520	COG4651	solute:proton antiporter activity
AL518_RS10525	COG2223	nitrite transmembrane transporter activity
AL518_RS10530	COG0737	Belongs to the 5'-nucleotidase family
AL518_RS10535	COG1278	Cold shock
AL518_RS10550	COG3735	TraB family
AL518_RS10555	COG2217	Heavy metal translocating P-type atpase
AL518_RS10565	COG1585	Membrane protein implicated in regulation of membrane protease activity
AL518_RS10570	COG0330	HflC and HflK could
AL518_RS10585	COG0010	Belongs to the arginase family
AL518_RS10595	COG0602	queuosine metabolic process
AL518_RS10600	COG2134	cdp-diacylglycerol pyrophosphatase
AL518_RS10605	COG2814	Major facilitator Superfamily
AL518_RS10620	COG0436	Aminotransferase
AL518_RS10630	COG0720	synthase
AL518_RS10635	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AL518_RS10640	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL518_RS10645	COG0175	sulfate reduction
AL518_RS10650	COG0277	FAD linked oxidase domain protein
AL518_RS10655	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL518_RS10660	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AL518_RS10665	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AL518_RS10670	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AL518_RS10675	COG2233	PERMEase
AL518_RS10680	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AL518_RS10690	COG1388	LysM domain
AL518_RS10690	COG1470	cell adhesion involved in biofilm formation
AL518_RS10700	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AL518_RS10730	COG2197	response regulator
AL518_RS10735	COG3850	Histidine kinase
AL518_RS10740	COG2223	nitrite transmembrane transporter activity
AL518_RS10750	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AL518_RS10755	COG1140	nitrate reductase beta subunit
AL518_RS10760	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AL518_RS10765	COG2181	nitrate reductase activity
AL518_RS10770	COG0583	DNA-binding transcription factor activity
AL518_RS10775	COG1802	Transcriptional regulator
AL518_RS10785	COG0246	Mannitol dehydrogenase
AL518_RS10795	COG2271	Major facilitator Superfamily
AL518_RS10800	COG1063	alcohol dehydrogenase
AL518_RS10805	COG4948	Mandelate Racemase Muconate Lactonizing
AL518_RS10810	COG1597	lipid kinase activity
AL518_RS10815	COG0826	peptidase U32
AL518_RS10820	COG3422	double-strand break repair
AL518_RS10825	COG0745	RESPONSE REGULATOR receiver
AL518_RS10830	COG2205	protein histidine kinase activity
AL518_RS10835	COG2814	Major facilitator Superfamily
AL518_RS10840	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL518_RS10845	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL518_RS10855	COG0667	Aldo Keto reductase
AL518_RS10865	COG2974	May be involved in recombination
AL518_RS10870	COG1940	carbohydrate kinase activity
AL518_RS10885	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AL518_RS10890	COG2207	Transcriptional regulator
AL518_RS10895	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL518_RS10895	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL518_RS10895	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AL518_RS10900	COG1363	Peptidase, m42
AL518_RS10905	COG0006	proline dipeptidase activity
AL518_RS10910	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL518_RS10915	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL518_RS10925	COG0419	ATPase involved in DNA repair
AL518_RS10930	COG0420	3'-5' exonuclease activity
AL518_RS10935	COG0745	RESPONSE REGULATOR receiver
AL518_RS10940	COG5002	protein histidine kinase activity
AL518_RS10965	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AL518_RS10970	COG0573	inorganic phosphate transmembrane transporter activity
AL518_RS10975	COG0573	inorganic phosphate transmembrane transporter activity
AL518_RS10990	COG2197	response regulator
AL518_RS11010	COG4932	domain protein
AL518_RS11010	COG2373	Large extracellular alpha-helical protein
AL518_RS11010	COG1388	LysM domain
AL518_RS11025	COG1393	Belongs to the ArsC family
AL518_RS11030	COG4783	chaperone-mediated protein folding
AL518_RS11035	COG0628	permease
AL518_RS11040	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AL518_RS11045	COG2716	regulation of RNA biosynthetic process
AL518_RS11050	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL518_RS11055	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AL518_RS11060	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AL518_RS11065	COG2321	neutral zinc metallopeptidase
AL518_RS11070	COG1444	tRNA N-acetyltransferase activity
AL518_RS11075	COG3468	outer membrane autotransporter barrel domain protein
AL518_RS11080	COG0400	carboxylic ester hydrolase activity
AL518_RS11090	COG1876	peptidase activity
AL518_RS11095	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL518_RS11100	COG1393	Belongs to the ArsC family
AL518_RS11105	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL518_RS11110	COG3539	Fimbrial protein
AL518_RS11115	COG3188	usher protein
AL518_RS11120	COG3121	Chaperone
AL518_RS11140	COG2197	response regulator
AL518_RS11145	COG3850	Histidine kinase
AL518_RS11150	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL518_RS11150	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL518_RS11155	COG3062	negative regulation of establishment of protein localization
AL518_RS11165	COG0437	4 iron, 4 sulfur cluster binding
AL518_RS11170	COG0348	domain, Protein
AL518_RS11175	COG3043	anaerobic respiration
AL518_RS11180	COG3005	denitrification pathway
AL518_RS11195	COG0494	nUDIX hydrolase
AL518_RS11200	COG0280	phosphate acetyltransferase
AL518_RS11200	COG0281	malic enzyme
AL518_RS11215	COG0840	transmembrane signaling receptor activity
AL518_RS11220	COG1028	Short-chain dehydrogenase reductase Sdr
AL518_RS11225	COG0583	DNA-binding transcription factor activity
AL518_RS11230	COG0583	DNA-binding transcription factor activity
AL518_RS11235	COG1335	isochorismatase
AL518_RS11245	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AL518_RS11250	COG0488	(ABC) transporter
AL518_RS11255	COG4574	serine-type endopeptidase inhibitor activity
AL518_RS11270	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL518_RS11275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL518_RS11275	COG1263	PTS System
AL518_RS11320	COG2204	response regulator
AL518_RS11335	COG3976	FMN-binding domain protein
AL518_RS11335	COG1053	succinate dehydrogenase
AL518_RS11350	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL518_RS11355	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL518_RS11360	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL518_RS11365	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AL518_RS11370	COG1138	Cytochrome C-type biogenesis protein
AL518_RS11375	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL518_RS11380	COG3088	subunit of a heme lyase
AL518_RS11380	COG4235	cytochrome complex assembly
AL518_RS11385	COG4235	cytochrome complex assembly
AL518_RS11385	COG3088	subunit of a heme lyase
AL518_RS11400	COG3691	Protein conserved in bacteria
AL518_RS11405	COG0183	Belongs to the thiolase family
AL518_RS11410	COG1024	Enoyl-CoA hydratase
AL518_RS11410	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL518_RS11415	COG2062	phosphohistidine phosphatase, SixA
AL518_RS11420	COG2840	Smr protein MutS2
AL518_RS11425	COG2890	protein-(glutamine-N5) methyltransferase activity
AL518_RS11430	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AL518_RS11440	COG3366	ferrous iron transmembrane transporter activity
AL518_RS11445	COG0700	Nucleoside recognition
AL518_RS11450	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AL518_RS11455	COG0583	DNA-binding transcription factor activity
AL518_RS11465	COG0730	response to heat
AL518_RS11470	COG3101	peptidyl-lysine hydroxylation
AL518_RS11490	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL518_RS11520	COG4232	protein-disulfide reductase activity
AL518_RS11530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL518_RS11540	COG0697	spore germination
AL518_RS11550	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL518_RS11555	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AL518_RS11560	COG0101	tRNA pseudouridine synthase activity
AL518_RS11565	COG0586	Pfam SNARE associated Golgi protein
AL518_RS11570	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AL518_RS11575	COG0285	dihydrofolate synthase activity
AL518_RS11580	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AL518_RS11585	COG1286	toxin biosynthetic process
AL518_RS11590	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AL518_RS11600	COG0163	prenyltransferase activity
AL518_RS11605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL518_RS11615	COG4160	amino acid transport
AL518_RS11620	COG4598	ABC transporter
AL518_RS11625	COG1090	epimerase
AL518_RS11630	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AL518_RS11635	COG0625	glutathione transferase activity
AL518_RS11640	COG0625	glutathione transferase activity
AL518_RS11645	COG0622	Phosphoesterase
AL518_RS11650	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AL518_RS11655	COG1609	Transcriptional regulator
AL518_RS11660	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL518_RS11670	COG3037	sugar-specific permease SgaT UlaA
AL518_RS11675	COG3959	Transketolase, thiamine diphosphate binding domain
AL518_RS11680	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AL518_RS11685	COG0280	phosphate acetyltransferase
AL518_RS11685	COG0857	belongs to the CobB CobQ family
AL518_RS11690	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AL518_RS11695	COG3092	negative regulation of chromosome organization
AL518_RS11700	COG3013	Belongs to the UPF0304 family
AL518_RS11705	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL518_RS11710	COG0471	metal ion transport
AL518_RS11710	COG0490	domain, Protein
AL518_RS11715	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AL518_RS11720	COG0436	Aminotransferase
AL518_RS11725	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL518_RS11730	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AL518_RS11740	COG2897	thiosulfate sulfurtransferase activity
AL518_RS11745	COG0398	Pfam SNARE associated Golgi protein
AL518_RS11750	COG0583	DNA-binding transcription factor activity
AL518_RS11765	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL518_RS11765	COG0649	NAD binding
AL518_RS11770	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AL518_RS11775	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AL518_RS11785	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AL518_RS11795	COG0839	Belongs to the complex I subunit 6 family
AL518_RS11805	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AL518_RS11810	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL518_RS11815	COG1007	ATP synthesis coupled electron transport
AL518_RS11845	COG0534	Mate efflux family protein
AL518_RS11850	COG4166	transmembrane transport
AL518_RS11860	COG1472	Belongs to the glycosyl hydrolase 3 family
AL518_RS11865	COG1609	Transcriptional regulator
AL518_RS11870	COG2271	Major facilitator Superfamily
AL518_RS11890	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AL518_RS11895	COG0437	4 iron, 4 sulfur cluster binding
AL518_RS11900	COG5557	Pfam Polysulphide reductase, NrfD
AL518_RS11905	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AL518_RS11910	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AL518_RS11915	COG1773	rubredoxin
AL518_RS11920	COG1811	Na channel or pump
AL518_RS11930	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AL518_RS11935	COG0583	DNA-binding transcription factor activity
AL518_RS11955	COG1169	isochorismate synthase
AL518_RS11960	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AL518_RS11965	COG0596	Alpha beta hydrolase
AL518_RS11970	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AL518_RS11975	COG1441	menaquinone biosynthetic process
AL518_RS12020	COG0814	amino acid
AL518_RS12030	COG4269	membrane
AL518_RS12035	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AL518_RS12040	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AL518_RS12050	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AL518_RS12055	COG0314	molybdopterin synthase activity
AL518_RS12070	COG0670	Belongs to the BI1 family
AL518_RS12080	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL518_RS12090	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AL518_RS12105	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL518_RS12115	COG0784	Response regulator, receiver
AL518_RS12115	COG2205	protein histidine kinase activity
AL518_RS12135	COG0642	Histidine kinase
AL518_RS12135	COG2198	Histidine kinase
AL518_RS12140	COG0842	Transport permease protein
AL518_RS12145	COG0842	Transport permease protein
AL518_RS12150	COG1131	(ABC) transporter
AL518_RS12155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL518_RS12160	COG1309	transcriptional regulator
AL518_RS12175	COG2274	protein secretion by the type I secretion system
AL518_RS12185	COG0513	Belongs to the DEAD box helicase family
AL518_RS12200	COG2207	Transcriptional regulator
AL518_RS12285	COG1802	Transcriptional regulator
AL518_RS12285	COG4626	Terminase
AL518_RS12295	COG4725	Belongs to the MT-A70-like family
AL518_RS12310	COG1403	HNH endonuclease
AL518_RS12320	COG1724	mRNA binding
AL518_RS12325	COG1598	PFAM Uncharacterised protein family UPF0150
AL518_RS12340	COG3179	chitinase
AL518_RS12460	COG5301	cellulose 1,4-beta-cellobiosidase activity
AL518_RS12465	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AL518_RS12470	COG1442	glycosyl transferase family 8
AL518_RS12495	COG3082	Protein of unknown function (DUF1414)
AL518_RS12500	COG3081	Nucleoid-associated protein
AL518_RS12505	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AL518_RS12510	COG1061	Type III restriction enzyme res subunit
AL518_RS12520	COG1187	pseudouridine synthase activity
AL518_RS12525	COG2814	Major facilitator Superfamily
AL518_RS12535	COG4172	Belongs to the ABC transporter superfamily
AL518_RS12540	COG4239	(ABC) transporter, permease
AL518_RS12545	COG4174	ABC transporter (Permease)
AL518_RS12550	COG4166	transmembrane transport
AL518_RS12555	COG2200	EAL domain
AL518_RS12565	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
AL518_RS12570	COG0668	transmembrane transport
AL518_RS12575	COG1126	abc transporter atp-binding protein
AL518_RS12580	COG0765	amino acid transport
AL518_RS12585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL518_RS12595	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL518_RS12595	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL518_RS12600	COG1105	Belongs to the carbohydrate kinase PfkB family
AL518_RS12605	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AL518_RS12605	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL518_RS12605	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL518_RS12610	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AL518_RS12625	COG2855	membrane
AL518_RS12635	COG0583	DNA-binding transcription factor activity
AL518_RS12640	COG0833	amino acid
AL518_RS12650	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL518_RS12660	COG4771	TonB-dependent receptor
AL518_RS12665	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL518_RS12665	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL518_RS12670	COG0489	protein tyrosine kinase activity
AL518_RS12675	COG0572	uridine kinase
AL518_RS12685	COG2982	Protein involved in outer membrane biogenesis
AL518_RS12690	COG3069	C4-dicarboxylate transmembrane transporter activity
AL518_RS12695	COG1253	flavin adenine dinucleotide binding
AL518_RS12700	COG1091	dTDP-4-dehydrorhamnose reductase activity
AL518_RS12705	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AL518_RS12725	COG2030	dehydratase
AL518_RS12760	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AL518_RS12835	COG3501	Rhs element vgr protein
AL518_RS12885	COG3501	Rhs element vgr protein
AL518_RS13000	COG0582	viral genome integration into host DNA
AL518_RS13035	COG1122	ATPase activity
AL518_RS13040	COG1122	ATPase activity
AL518_RS13050	COG2194	sulfuric ester hydrolase activity
AL518_RS13060	COG0672	)-iron permease
AL518_RS13085	COG3615	Tellurite resistance protein tehB
AL518_RS13090	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AL518_RS13095	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AL518_RS13115	COG3418	PFAM FlgN family protein
AL518_RS13120	COG2747	anti-sigma28 factor FlgM
AL518_RS13130	COG1815	bacterial-type flagellum-dependent cell motility
AL518_RS13135	COG1558	bacterial-type flagellum-dependent cell motility
AL518_RS13185	COG1256	bacterial-type flagellum assembly
AL518_RS13190	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL518_RS13205	COG1338	Plays a role in the flagellum-specific transport system
AL518_RS13225	COG1580	Controls the rotational direction of flagella during chemotaxis
AL518_RS13235	COG3144	bacterial-type flagellum assembly
AL518_RS13240	COG2882	bacterial-type flagellum organization
AL518_RS13255	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AL518_RS13335	COG1126	abc transporter atp-binding protein
AL518_RS13350	COG0506	proline dehydrogenase activity
AL518_RS13350	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AL518_RS13350	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AL518_RS13405	COG0371	Dehydrogenase
AL518_RS13415	COG0390	transport system, permease component
AL518_RS13420	COG4619	ABC transporter
AL518_RS13430	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AL518_RS13435	COG1530	ribonuclease E activity
AL518_RS13440	COG0564	pseudouridine synthase activity
AL518_RS13445	COG0424	maF-like protein
AL518_RS13450	COG1399	metal-binding, possibly nucleic acid-binding protein
AL518_RS13460	COG0416	fatty acid biosynthetic process
AL518_RS13470	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AL518_RS13485	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL518_RS13490	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AL518_RS13495	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AL518_RS13505	COG0470	DNA polymerase III
AL518_RS13510	COG0084	hydrolase, TatD family'
AL518_RS13515	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL518_RS13515	COG1263	PTS System
AL518_RS13525	COG0671	phosphoesterase, PA-phosphatase related
AL518_RS13530	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
AL518_RS13535	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AL518_RS13545	COG0023	Translation Initiation Factor
AL518_RS13560	COG3265	gluconokinase activity
AL518_RS13565	COG2610	gluconate transmembrane transporter activity
AL518_RS13570	COG3739	integral membrane protein
AL518_RS13575	COG2814	Major facilitator Superfamily
AL518_RS13585	COG0586	Pfam SNARE associated Golgi protein
AL518_RS13595	COG2259	Doxx family
AL518_RS13605	COG0583	DNA-binding transcription factor activity
AL518_RS13610	COG0697	spore germination
AL518_RS13615	COG1396	sequence-specific DNA binding
AL518_RS13620	COG1054	Belongs to the UPF0176 family
AL518_RS13630	COG0628	permease
AL518_RS13640	COG0477	Major facilitator Superfamily
AL518_RS13665	COG1275	C4-dicarboxylate transporter malic acid transport protein
AL518_RS13685	COG1349	DNA-binding transcription factor activity
AL518_RS13690	COG1882	Formate acetyltransferase
AL518_RS13695	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AL518_RS13715	COG2719	SpoVR family
AL518_RS13720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL518_RS13725	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AL518_RS13745	COG5645	(Lipo)protein
AL518_RS13760	COG4178	(ABC) transporter
AL518_RS13765	COG2718	Belongs to the UPF0229 family
AL518_RS13770	COG2766	serine protein kinase
AL518_RS13775	COG3713	MltA-interacting MipA family protein
AL518_RS13795	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL518_RS13800	COG3139	Protein of unknown function (DUF1315)
AL518_RS13805	COG1335	isochorismatase
AL518_RS13810	COG0252	asparaginase activity
AL518_RS13815	COG0616	signal peptide processing
AL518_RS13820	COG0778	Nitroreductase
AL518_RS13830	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
AL518_RS13835	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AL518_RS13845	COG0494	nUDIX hydrolase
AL518_RS13850	COG0708	Exodeoxyribonuclease III
AL518_RS13890	COG0788	formyltetrahydrofolate deformylase activity
AL518_RS13895	COG3012	SEC-C Motif Domain Protein
AL518_RS13900	COG0745	RESPONSE REGULATOR receiver
AL518_RS13905	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AL518_RS13915	COG1435	thymidine kinase activity
AL518_RS13920	COG1012	belongs to the aldehyde dehydrogenase family
AL518_RS13920	COG1454	alcohol dehydrogenase
AL518_RS13925	COG2095	MarC family integral membrane protein
AL518_RS13940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL518_RS13945	COG0444	Belongs to the ABC transporter superfamily
AL518_RS13955	COG0537	adenosine 5'-monophosphoramidase activity
AL518_RS13960	COG5633	Lipoprotein
AL518_RS13965	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
AL518_RS13980	COG3150	esterase
AL518_RS13985	COG1830	Aldolase
AL518_RS13995	COG0531	amino acid
AL518_RS14000	COG1177	transmembrane transport
AL518_RS14020	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AL518_RS14025	COG2249	NAD(P)H dehydrogenase (quinone) activity
AL518_RS14035	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL518_RS14035	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL518_RS14045	COG4172	Belongs to the ABC transporter superfamily
AL518_RS14050	COG4172	Belongs to the ABC transporter superfamily
AL518_RS14055	COG4171	peptide transport system, permease
AL518_RS14065	COG4166	transmembrane transport
AL518_RS14070	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AL518_RS14075	COG1842	Phage shock protein A
AL518_RS14085	COG1983	PspC domain protein
AL518_RS14095	COG3106	COG3106 Predicted ATPase
AL518_RS14100	COG3768	UPF0283 membrane protein
AL518_RS14115	COG2897	thiosulfate sulfurtransferase activity
AL518_RS14130	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AL518_RS14135	COG4948	Mandelate Racemase Muconate Lactonizing
AL518_RS14140	COG2866	Carboxypeptidase
AL518_RS14145	COG4166	transmembrane transport
AL518_RS14150	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AL518_RS14155	COG1388	LysM domain
AL518_RS14155	COG1376	ErfK ybiS ycfS ynhG family protein
AL518_RS14200	COG0307	riboflavin synthase, alpha
AL518_RS14220	COG2814	Major facilitator Superfamily
AL518_RS14235	COG0727	PFAM Uncharacterised protein family (UPF0153)
AL518_RS14240	COG3047	cAMP biosynthetic process
AL518_RS14250	COG0159	tryptophan synthase activity
AL518_RS14255	COG0133	tryptophan synthase activity
AL518_RS14260	COG0134	indole-3-glycerol-phosphate synthase activity
AL518_RS14260	COG0135	phosphoribosylanthranilate isomerase activity
AL518_RS14270	COG0512	Glutamine amidotransferase of anthranilate synthase
AL518_RS14270	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AL518_RS14285	COG0009	L-threonylcarbamoyladenylate synthase
AL518_RS14310	COG2211	Major facilitator Superfamily
AL518_RS14330	COG0765	amino acid transport
AL518_RS14335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL518_RS14345	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AL518_RS14350	COG2207	Transcriptional regulator
AL518_RS14355	COG1028	Short-chain dehydrogenase reductase Sdr
AL518_RS14410	COG0322	excinuclease ABC activity
AL518_RS14425	COG1187	pseudouridine synthase activity
AL518_RS14435	COG0406	alpha-ribazole phosphatase activity
AL518_RS14445	COG1028	Short-chain dehydrogenase reductase Sdr
AL518_RS14450	COG0616	signal peptide processing
AL518_RS14465	COG0583	DNA-binding transcription factor activity
AL518_RS14485	COG1496	oxidoreductase activity
AL518_RS14490	COG2226	methyltransferase
AL518_RS14495	COG1971	Probably functions as a manganese efflux pump
AL518_RS14505	COG3716	PTS system mannose fructose sorbose family IID component
AL518_RS14510	COG3715	PTS system
AL518_RS14515	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL518_RS14515	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL518_RS14520	COG1253	flavin adenine dinucleotide binding
AL518_RS14525	COG2200	EAL domain
AL518_RS14530	COG1447	Phosphotransferase system cellobiose-specific component IIA
AL518_RS14540	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AL518_RS14545	COG1446	asparaginase
AL518_RS14560	COG1760	l-serine dehydratase
AL518_RS14570	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AL518_RS14585	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AL518_RS14600	COG3141	response to X-ray
AL518_RS14605	COG3097	Belongs to the UPF0267 family
AL518_RS14620	COG1770	oligopeptidase
AL518_RS14625	COG2267	carboxylic ester hydrolase activity
AL518_RS14635	COG2372	response to copper ion
AL518_RS14655	COG1105	Belongs to the carbohydrate kinase PfkB family
AL518_RS14675	COG3753	Protein conserved in bacteria
AL518_RS14680	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL518_RS14690	COG1652	LysM domain
AL518_RS14740	COG3008	intermembrane lipid transfer
AL518_RS14745	COG2995	paraquat-inducible protein a
AL518_RS14750	COG1956	GAF domain-containing protein
AL518_RS14760	COG0793	Belongs to the peptidase S41A family
AL518_RS14765	COG0501	Belongs to the peptidase M48B family
AL518_RS14770	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AL518_RS14775	COG2814	Major facilitator Superfamily
AL518_RS14780	COG0583	DNA-binding transcription factor activity
AL518_RS14785	COG4136	ATPase activity
AL518_RS14790	COG4135	transport system, permease component
AL518_RS14810	COG0791	NLP P60 protein
AL518_RS14815	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AL518_RS14820	COG2056	Na+-H+ antiporter family
AL518_RS14825	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AL518_RS14830	COG0346	lactoylglutathione lyase activity
AL518_RS14835	COG1902	pentaerythritol trinitrate reductase activity
AL518_RS14840	COG1091	dTDP-4-dehydrorhamnose reductase activity
AL518_RS14845	COG0583	DNA-binding transcription factor activity
AL518_RS14850	COG3313	Fe-S protein
AL518_RS14855	COG1289	transmembrane transporter activity
AL518_RS14860	COG1566	PFAM secretion protein HlyD family protein
AL518_RS14875	COG3133	Outer membrane lipoprotein
AL518_RS14880	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AL518_RS14885	COG3895	Periplasmic Protein
AL518_RS14915	COG0583	DNA-binding transcription factor activity
AL518_RS14920	COG0625	glutathione transferase activity
AL518_RS14925	COG3104	oligopeptide transport
AL518_RS14930	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AL518_RS14940	COG4659	FMN binding
AL518_RS14945	COG4658	electron transport chain
AL518_RS14960	COG4657	Part of a membrane complex involved in electron transport
AL518_RS14970	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AL518_RS14975	COG0697	spore germination
AL518_RS14990	COG1069	ribulokinase activity
AL518_RS14995	COG1879	ABC-type sugar transport system periplasmic component
AL518_RS15000	COG1129	ABC transporter
AL518_RS15005	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL518_RS15020	COG0673	inositol 2-dehydrogenase activity
AL518_RS15025	COG0385	Bile acid
AL518_RS15055	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AL518_RS15060	COG1263	PTS System
AL518_RS15060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL518_RS15065	COG1609	Transcriptional regulator
AL518_RS15070	COG5339	Protein conserved in bacteria
AL518_RS15075	COG1482	cell wall glycoprotein biosynthetic process
AL518_RS15080	COG0114	fumarate hydratase activity
AL518_RS15090	COG0589	response to stress
AL518_RS15100	COG0826	peptidase U32
AL518_RS15110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL518_RS15120	COG2814	Major facilitator Superfamily
AL518_RS15125	COG0840	transmembrane signaling receptor activity
AL518_RS15130	COG0500	methyltransferase
AL518_RS15150	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AL518_RS15165	COG3265	gluconokinase activity
AL518_RS15175	COG1028	Short-chain dehydrogenase reductase Sdr
AL518_RS15200	COG4221	oxidoreductase activity
AL518_RS15215	COG0477	Major facilitator Superfamily
AL518_RS15220	COG1858	cytochrome C peroxidase
AL518_RS15230	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AL518_RS15235	COG1940	carbohydrate kinase activity
AL518_RS15240	COG0583	DNA-binding transcription factor activity
AL518_RS15245	COG2814	Major facilitator Superfamily
AL518_RS15250	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AL518_RS15255	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AL518_RS15265	COG0531	amino acid
AL518_RS15280	COG0745	RESPONSE REGULATOR receiver
AL518_RS15285	COG2205	protein histidine kinase activity
AL518_RS15290	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AL518_RS15305	COG2226	methyltransferase
AL518_RS15310	COG3591	Belongs to the peptidase S1B family
AL518_RS15315	COG1643	Atp-dependent helicase
AL518_RS15325	COG3784	Protein of unknown function (DUF1318)
AL518_RS15335	COG2911	Protein conserved in bacteria
AL518_RS15340	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL518_RS15355	COG3187	Heat shock protein
AL518_RS15360	COG3042	response to heat
AL518_RS15365	COG1285	pathogenesis
AL518_RS15370	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL518_RS15370	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AL518_RS15370	COG1013	pyruvate-flavodoxin oxidoreductase activity
AL518_RS15370	COG0674	pyruvate-flavodoxin oxidoreductase activity
AL518_RS15375	COG0493	'glutamate synthase
AL518_RS15375	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL518_RS15380	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL518_RS15390	COG0251	oxidation-reduction process
AL518_RS15405	COG0402	S-adenosylhomocysteine deaminase activity
AL518_RS15435	COG0640	Transcriptional regulator
AL518_RS15455	COG2050	protein possibly involved in aromatic compounds catabolism
AL518_RS15460	COG0247	lactate metabolic process
AL518_RS15460	COG0277	FAD linked oxidase domain protein
AL518_RS15465	COG0628	permease
AL518_RS15470	COG0574	Belongs to the PEP-utilizing enzyme family
AL518_RS15470	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AL518_RS15485	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AL518_RS15490	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL518_RS15520	COG3720	iron ion transport
AL518_RS15525	COG4558	Periplasmic binding protein
AL518_RS15530	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL518_RS15535	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AL518_RS15550	COG0095	Lipoate-protein ligase
AL518_RS15555	COG0791	NLP P60 protein
AL518_RS15565	COG2076	Multidrug Resistance protein
AL518_RS15575	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AL518_RS15585	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AL518_RS15585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL518_RS15590	COG0463	Glycosyl transferase, family 2
AL518_RS15595	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AL518_RS15600	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
AL518_RS15605	COG4139	cobalamin transport
AL518_RS15615	COG0776	regulation of translation
AL518_RS15620	COG0072	phenylalanine-tRNA ligase activity
AL518_RS15620	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL518_RS15640	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AL518_RS15645	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AL518_RS15670	COG0840	transmembrane signaling receptor activity
AL518_RS15685	COG3152	Membrane
AL518_RS15695	COG0601	transmembrane transport
AL518_RS15700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL518_RS15710	COG1124	(ABC) transporter
AL518_RS15715	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL518_RS15720	COG0814	amino acid
AL518_RS15735	COG3001	Fructosamine kinase
AL518_RS15745	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL518_RS15750	COG1988	membrane-bound metal-dependent
AL518_RS15755	COG1823	symporter activity
AL518_RS15770	COG1607	acyl-coa hydrolase
AL518_RS15780	COG2350	Protein conserved in bacteria
AL518_RS15785	COG0783	Belongs to the Dps family
AL518_RS15800	COG3099	Belongs to the UPF0263 family
AL518_RS15805	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL518_RS15815	COG3678	ATP-independent chaperone mediated protein folding
AL518_RS15825	COG1028	Short-chain dehydrogenase reductase Sdr
AL518_RS15835	COG1120	ATPase activity
AL518_RS15840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL518_RS15845	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL518_RS15865	COG1683	Conserved Protein
AL518_RS15870	COG2259	Doxx family
AL518_RS15880	COG2116	formate transmembrane transporter activity
AL518_RS15890	COG0477	Major facilitator Superfamily
AL518_RS15895	COG2885	chlorophyll binding
AL518_RS15900	COG2199	diguanylate cyclase activity
AL518_RS15910	COG2207	Transcriptional regulator
AL518_RS15935	COG0583	DNA-binding transcription factor activity
AL518_RS15940	COG0840	transmembrane signaling receptor activity
AL518_RS15950	COG0583	DNA-binding transcription factor activity
AL518_RS15970	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AL518_RS15990	COG3122	Protein conserved in bacteria
AL518_RS16000	COG3479	Phenolic acid decarboxylase
AL518_RS16010	COG2153	protein acetylation
AL518_RS16015	COG0538	isocitrate dehydrogenase activity
AL518_RS16020	COG1187	pseudouridine synthase activity
AL518_RS16035	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AL518_RS16040	COG1595	DNA-templated transcription, initiation
AL518_RS16065	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AL518_RS16070	COG2188	Transcriptional regulator
AL518_RS16090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL518_RS16095	COG1397	ADP-ribosylglycohydrolase
AL518_RS16100	COG2211	Major facilitator Superfamily
AL518_RS16125	COG0745	RESPONSE REGULATOR receiver
AL518_RS16130	COG2205	protein histidine kinase activity
AL518_RS16135	COG2850	peptidyl-arginine hydroxylation
AL518_RS16140	COG3969	phosphoadenosine phosphosulfate
AL518_RS16145	COG1475	DNA binding
AL518_RS16160	COG4591	ABC-type transport system involved in lipoprotein release permease component
AL518_RS16170	COG4591	ABC-type transport system involved in lipoprotein release permease component
AL518_RS16185	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AL518_RS16190	COG3134	Outer membrane lipoprotein
AL518_RS16195	COG1252	NADH dehydrogenase
AL518_RS16200	COG1966	Carbon starvation protein
AL518_RS16205	COG2879	small protein
AL518_RS16215	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AL518_RS16235	COG0179	Fumarylacetoacetate (FAA) hydrolase
AL518_RS16245	COG0850	regulation of cytokinetic process
AL518_RS16250	COG2894	cell division
AL518_RS16255	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AL518_RS16260	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AL518_RS16265	COG0318	PFAM AMP-dependent synthetase and ligase
AL518_RS16270	COG1187	pseudouridine synthase activity
AL518_RS16275	COG3065	identical protein binding
AL518_RS16285	COG1199	ATP-dependent helicase activity
AL518_RS16295	COG0251	oxidation-reduction process
AL518_RS16300	COG1609	Transcriptional regulator
AL518_RS16305	COG1757	Na H antiporter
AL518_RS16310	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AL518_RS16315	COG2076	Multidrug Resistance protein
AL518_RS16320	COG2076	Multidrug Resistance protein
AL518_RS16325	COG0800	Aldolase
AL518_RS16330	COG0129	dihydroxy-acid dehydratase activity
AL518_RS16335	COG0363	glucosamine-6-phosphate deaminase activity
AL518_RS16340	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AL518_RS16345	COG1737	Transcriptional regulator
AL518_RS16350	COG0469	pyruvate kinase activity
AL518_RS16355	COG1560	Kdo2-lipid A biosynthetic process
AL518_RS16360	COG0739	heme binding
AL518_RS16365	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AL518_RS16370	COG1121	(ABC) transporter
AL518_RS16375	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AL518_RS16385	COG0632	four-way junction helicase activity
AL518_RS16395	COG0217	transcriptional regulatory protein
AL518_RS16400	COG0494	nUDIX hydrolase
AL518_RS16415	COG1801	Protein of unknown function DUF72
AL518_RS16420	COG3788	relative of glutathione S-transferase, MAPEG superfamily
AL518_RS16425	COG1113	amino acid transport
AL518_RS16435	COG0500	methyltransferase
AL518_RS16440	COG3142	Participates in the control of copper homeostasis
AL518_RS16445	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AL518_RS16450	COG3102	Protein conserved in bacteria
AL518_RS16470	COG0673	inositol 2-dehydrogenase activity
AL518_RS16480	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL518_RS16485	COG0477	Major facilitator Superfamily
AL518_RS16495	COG3381	protein complex oligomerization
AL518_RS16500	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AL518_RS16505	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL518_RS16510	COG3104	oligopeptide transport
AL518_RS16515	COG4134	Bacterial extracellular solute-binding protein
AL518_RS16525	COG1764	response to oxidative stress
AL518_RS16540	COG3065	identical protein binding
AL518_RS16545	COG0659	secondary active sulfate transmembrane transporter activity
AL518_RS16565	COG2890	protein-(glutamine-N5) methyltransferase activity
AL518_RS16570	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AL518_RS16575	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AL518_RS16590	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AL518_RS16605	COG0012	GTP binding
AL518_RS16625	COG2223	nitrite transmembrane transporter activity
AL518_RS16635	COG0531	amino acid
AL518_RS16640	COG1982	Orn Lys Arg decarboxylase major
AL518_RS16645	COG0531	amino acid
AL518_RS16650	COG3443	Belongs to the bacterial solute-binding protein 9 family
AL518_RS16655	COG0477	Major facilitator Superfamily
AL518_RS16660	COG1566	PFAM secretion protein HlyD family protein
AL518_RS16665	COG2207	Transcriptional regulator
AL518_RS16670	COG0243	molybdopterin cofactor binding
AL518_RS16750	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AL518_RS16765	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
AL518_RS16785	COG4656	Part of a membrane complex involved in electron transport
AL518_RS16805	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AL518_RS16810	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AL518_RS16810	COG1648	precorrin-2 dehydrogenase activity
AL518_RS16825	COG3708	Transcriptional regulator
AL518_RS16825	COG2207	Transcriptional regulator
AL518_RS16920	COG4964	Belongs to the GSP D family
AL518_RS16960	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AL518_RS16980	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL518_RS17040	COG2010	Cytochrome c
AL518_RS17040	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AL518_RS17060	COG2239	Acts as a magnesium transporter
AL518_RS17085	COG0586	Pfam SNARE associated Golgi protein
AL518_RS17090	COG0387	Pfam Sodium calcium exchanger
AL518_RS17100	COG1702	phosphate starvation-inducible protein PhoH
AL518_RS17110	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AL518_RS17115	COG0745	RESPONSE REGULATOR receiver
AL518_RS17125	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AL518_RS17130	COG0840	transmembrane signaling receptor activity
AL518_RS17135	COG0840	transmembrane signaling receptor activity
AL518_RS17150	COG0835	chemotaxis
AL518_RS17155	COG2198	Histidine kinase
AL518_RS17155	COG0643	Histidine kinase
AL518_RS17160	COG1360	Flagellar Motor Protein
AL518_RS17185	COG3592	Divergent 4Fe-4S mono-cluster
AL518_RS17190	COG2388	GCN5-related N-acetyl-transferase
AL518_RS17205	COG0768	penicillin binding
AL518_RS17210	COG2194	sulfuric ester hydrolase activity
AL518_RS17220	COG1335	isochorismatase
AL518_RS17225	COG2814	Major facilitator Superfamily
AL518_RS17245	COG2207	Transcriptional regulator
AL518_RS17250	COG3038	cytochrome b561
AL518_RS17305	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AL518_RS17310	COG0322	excinuclease ABC activity
AL518_RS17315	COG2197	response regulator
AL518_RS17335	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AL518_RS17365	COG0366	Alpha amylase catalytic
AL518_RS17370	COG1538	Outer membrane efflux protein
AL518_RS17375	COG1196	nuclear chromosome segregation
AL518_RS17375	COG3264	Mechanosensitive ion channel
AL518_RS17510	COG0670	Belongs to the BI1 family
AL518_RS17515	COG2920	part of a sulfur-relay system
AL518_RS17520	COG1254	Belongs to the acylphosphatase family
AL518_RS17525	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AL518_RS17530	COG3785	DNA binding
AL518_RS17535	COG1832	CoA-binding protein
AL518_RS17545	COG1803	Methylglyoxal synthase
AL518_RS17550	COG0210	DNA helicase
AL518_RS17555	COG3304	Inner membrane component domain
AL518_RS17560	COG1289	transmembrane transporter activity
AL518_RS17565	COG3070	regulator of competence-specific genes
AL518_RS17585	COG1067	ATP-dependent peptidase activity
AL518_RS17595	COG0583	DNA-binding transcription factor activity
AL518_RS17600	COG3130	regulation of translation
AL518_RS17605	COG3009	Protein conserved in bacteria
AL518_RS17610	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AL518_RS17610	COG3008	intermembrane lipid transfer
AL518_RS17615	COG2995	paraquat-inducible protein a
AL518_RS17620	COG0488	(ABC) transporter
AL518_RS17625	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AL518_RS17625	COG0116	Belongs to the methyltransferase superfamily
AL518_RS17635	COG0633	Ferredoxin
AL518_RS17635	COG3217	Mosc domain protein beta barrel domain protein
AL518_RS17650	COG0308	aminopeptidase N
AL518_RS17655	COG3706	GGDEF domain
AL518_RS17660	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AL518_RS17665	COG0017	Asparaginyl-tRNA synthetase
AL518_RS17675	COG1448	Aminotransferase
AL518_RS17680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AL518_RS17685	COG3108	Peptidase M15
AL518_RS17690	COG2989	Protein conserved in bacteria
AL518_RS17695	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AL518_RS17705	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
AL518_RS17710	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL518_RS17715	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AL518_RS17730	COG2233	PERMEase
AL518_RS17735	COG2233	PERMEase
AL518_RS17740	COG3173	Aminoglycoside phosphotransferase
AL518_RS17745	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AL518_RS17750	COG2835	tetraacyldisaccharide 4'-kinase activity
AL518_RS17755	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AL518_RS17765	COG3214	Protein conserved in bacteria
AL518_RS17780	COG1663	tetraacyldisaccharide 4'-kinase activity
AL518_RS17790	COG2333	competence protein COMEC
AL518_RS17790	COG0658	competence protein
AL518_RS17800	COG0539	negative regulation of cytoplasmic translation
AL518_RS17810	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AL518_RS17815	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AL518_RS17820	COG2323	membrane
AL518_RS17825	COG0252	asparaginase activity
AL518_RS17830	COG1944	ATP diphosphatase activity
AL518_RS17835	COG2116	formate transmembrane transporter activity
AL518_RS17840	COG1882	Formate acetyltransferase
AL518_RS17845	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AL518_RS17870	COG3302	dmso reductase anchor subunit
AL518_RS17875	COG0437	4 iron, 4 sulfur cluster binding
AL518_RS17880	COG0243	molybdopterin cofactor binding
AL518_RS17890	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AL518_RS17900	COG1674	ftsk spoiiie
AL518_RS17900	COG3107	peptidoglycan biosynthetic process
AL518_RS17905	COG1522	sequence-specific DNA binding
AL518_RS17910	COG0492	ferredoxin-NADP+ reductase activity
AL518_RS17915	COG2945	thiolester hydrolase activity
AL518_RS17915	COG0596	Alpha beta hydrolase
AL518_RS17925	COG4988	ABC transporter
AL518_RS17930	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AL518_RS17940	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AL518_RS17945	COG0542	response to heat
AL518_RS17950	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AL518_RS17955	COG1278	Cold shock
AL518_RS17960	COG2990	Protein conserved in bacteria
AL518_RS17965	COG3593	DNA synthesis involved in DNA repair
AL518_RS17970	COG2431	L-lysine efflux transmembrane transporter activity
AL518_RS17975	COG1151	hydroxylamine reductase activity
AL518_RS17980	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL518_RS17985	COG0028	Belongs to the TPP enzyme family
AL518_RS17990	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AL518_RS17995	COG0702	epimerase
AL518_RS18000	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL518_RS18005	COG3023	N-Acetylmuramoyl-L-alanine amidase
AL518_RS18020	COG1126	abc transporter atp-binding protein
AL518_RS18025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL518_RS18030	COG4215	(ABC) transporter
AL518_RS18035	COG4160	amino acid transport
AL518_RS18040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL518_RS18050	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AL518_RS18055	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AL518_RS18065	COG1177	transmembrane transport
AL518_RS18070	COG1176	ABC-type spermidine putrescine transport system, permease component I
AL518_RS18075	COG3842	ATPase activity
AL518_RS18080	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AL518_RS18095	COG0189	ligase activity
AL518_RS18125	COG0477	Major facilitator Superfamily
AL518_RS18130	COG0671	phosphoesterase, PA-phosphatase related
AL518_RS18135	COG1349	DNA-binding transcription factor activity
AL518_RS18140	COG0814	amino acid
AL518_RS18145	COG1760	l-serine dehydratase
AL518_RS18150	COG1686	Belongs to the peptidase S11 family
AL518_RS18170	COG1280	lysine exporter protein (LysE YggA)
AL518_RS18180	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AL518_RS18185	COG2814	Major facilitator Superfamily
AL518_RS18195	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AL518_RS18200	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL518_RS18210	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AL518_RS18220	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AL518_RS18235	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AL518_RS18250	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AL518_RS18255	COG1473	amidohydrolase
AL518_RS18260	COG3005	denitrification pathway
AL518_RS18265	COG0243	molybdopterin cofactor binding
AL518_RS18285	COG3716	PTS system mannose fructose sorbose family IID component
AL518_RS18290	COG3715	PTS system
AL518_RS18295	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL518_RS18295	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL518_RS18335	COG0246	Mannitol dehydrogenase
AL518_RS18340	COG2200	EAL domain
AL518_RS18345	COG2186	Transcriptional regulator
AL518_RS18355	COG0523	cobalamin synthesis protein
AL518_RS18360	COG0671	phosphoesterase, PA-phosphatase related
AL518_RS18365	COG0791	NLP P60 protein
AL518_RS18370	COG1113	amino acid transport
AL518_RS18375	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
AL518_RS18380	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AL518_RS18390	COG4175	Glycine betaine
AL518_RS18395	COG4176	ABC-type proline glycine betaine transport system permease component
AL518_RS18400	COG2113	Glycine betaine
AL518_RS18405	COG3539	Fimbrial protein
AL518_RS18410	COG3121	Chaperone
AL518_RS18415	COG3188	usher protein
AL518_RS18420	COG3539	Fimbrial protein
AL518_RS18425	COG1289	transmembrane transporter activity
AL518_RS18430	COG2925	Exonuclease
AL518_RS18435	COG2962	Rard protein
AL518_RS18440	COG0531	amino acid
AL518_RS18450	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL518_RS18455	COG0174	glutamine synthetase
AL518_RS18460	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AL518_RS18465	COG1917	Cupin 2, conserved barrel domain protein
AL518_RS18465	COG1396	sequence-specific DNA binding
AL518_RS18470	COG1012	belongs to the aldehyde dehydrogenase family
AL518_RS18475	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL518_RS18485	COG2814	Major facilitator Superfamily
AL518_RS18490	COG1380	Effector of murein hydrolase LrgA
AL518_RS18495	COG1346	cytolysis
AL518_RS18500	COG0295	cytidine deaminase activity
AL518_RS18505	COG0281	malic enzyme
AL518_RS18510	COG2949	membrane
AL518_RS18535	COG2311	Membrane
AL518_RS18540	COG0302	gtp cyclohydrolase
AL518_RS18545	COG0477	Major facilitator Superfamily
AL518_RS18550	COG0583	DNA-binding transcription factor activity
AL518_RS18565	COG0303	'Molybdopterin
AL518_RS18570	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AL518_RS18585	COG2943	transferase activity, transferring hexosyl groups
AL518_RS18590	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
AL518_RS18605	COG3275	phosphorelay sensor kinase activity
AL518_RS18610	COG3279	Response regulator of the LytR AlgR family
AL518_RS18625	COG1794	racemase activity, acting on amino acids and derivatives
AL518_RS18640	COG3961	Belongs to the TPP enzyme family
AL518_RS18645	COG0667	Aldo Keto reductase
AL518_RS18650	COG0110	maltose O-acetyltransferase activity
AL518_RS18660	COG1914	H( )-stimulated, divalent metal cation uptake system
AL518_RS18665	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AL518_RS18685	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AL518_RS18740	COG0726	polysaccharide deacetylase
AL518_RS18740	COG1649	PFAM Uncharacterised BCR, COG1649
AL518_RS18745	COG1215	transferase activity, transferring glycosyl groups
AL518_RS18755	COG3530	Putative quorum-sensing-regulated virulence factor
AL518_RS18760	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AL518_RS18765	COG3115	cell septum assembly
AL518_RS18780	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL518_RS18790	COG2190	(PTS) system
AL518_RS18800	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AL518_RS18810	COG4208	sulfate ABC transporter
AL518_RS18815	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AL518_RS18825	COG2837	iron assimilation
AL518_RS18840	COG0456	acetyltransferase
AL518_RS18845	COG3250	beta-galactosidase activity
AL518_RS18860	COG1671	Belongs to the UPF0178 family
AL518_RS18870	COG1174	glycine betaine transport
AL518_RS18875	COG1125	glycine betaine transport
AL518_RS18880	COG1174	glycine betaine transport
AL518_RS18885	COG1732	Glycine betaine
AL518_RS18905	COG1464	Belongs to the NlpA lipoprotein family
AL518_RS18915	COG2354	Protein conserved in bacteria
AL518_RS18920	COG1686	Belongs to the peptidase S11 family
AL518_RS18925	COG4106	trans-aconitate 2-methyltransferase activity
AL518_RS18935	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AL518_RS18940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL518_RS18945	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL518_RS18950	COG0583	DNA-binding transcription factor activity
AL518_RS18955	COG2249	NAD(P)H dehydrogenase (quinone) activity
AL518_RS18960	COG4628	conserved protein (DUF2132)
AL518_RS18965	COG0556	nucleotide-excision repair
AL518_RS19010	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AL518_RS19015	COG0561	phosphatase activity
AL518_RS19025	COG4149	molybdate abc transporter
AL518_RS19030	COG0725	ABC transporter, periplasmic molybdate-binding protein
AL518_RS19040	COG2005	Transcriptional regulator
AL518_RS19040	COG3585	molybdate ion transport
AL518_RS19045	COG1119	ATPase activity
AL518_RS19055	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AL518_RS19065	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AL518_RS19070	COG2017	converts alpha-aldose to the beta-anomer
AL518_RS19095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL518_RS19100	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL518_RS19120	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL518_RS19130	COG1230	cation diffusion facilitator family transporter
AL518_RS19145	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AL518_RS19170	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AL518_RS19175	COG2885	chlorophyll binding
AL518_RS19185	COG3064	Membrane
AL518_RS19190	COG0848	biopolymer transport protein
AL518_RS19195	COG0811	peptide transport
AL518_RS19200	COG0824	Thioesterase
AL518_RS19205	COG3790	cyd operon protein YbgE
AL518_RS19210	COG4890	Cyd operon protein YbgT
AL518_RS19215	COG1294	oxidase, subunit
AL518_RS19220	COG1271	oxidase subunit
AL518_RS19225	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AL518_RS19235	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL518_RS19240	COG0567	Dehydrogenase, E1 component
AL518_RS19250	COG1053	succinate dehydrogenase
AL518_RS19255	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AL518_RS19270	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AL518_RS19280	COG1984	allophanate hydrolase subunit 2
AL518_RS19285	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AL518_RS19290	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AL518_RS19300	COG0583	DNA-binding transcription factor activity
AL518_RS19305	COG2824	Alkylphosphonate utilization operon protein PhnA
AL518_RS19310	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AL518_RS19315	COG5212	phosphodiesterase
AL518_RS19320	COG0415	Belongs to the DNA photolyase family
AL518_RS19325	COG3272	Protein of unknown function (DUF1722)
AL518_RS19350	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AL518_RS19355	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AL518_RS19360	COG2205	protein histidine kinase activity
AL518_RS19365	COG0745	RESPONSE REGULATOR receiver
AL518_RS19375	COG0033	Phosphoglucomutase
AL518_RS19385	COG0596	Alpha beta hydrolase
AL518_RS19395	COG0716	FMN binding
AL518_RS19400	COG0735	belongs to the Fur family
AL518_RS19425	COG1263	PTS System
AL518_RS19425	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL518_RS19425	COG2190	(PTS) system
AL518_RS19435	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AL518_RS19440	COG1846	Transcriptional regulator
AL518_RS19440	COG1940	carbohydrate kinase activity
AL518_RS19450	COG0647	UMP catabolic process
AL518_RS19455	COG0367	asparagine synthase
AL518_RS19495	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL518_RS19500	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AL518_RS19505	COG1702	phosphate starvation-inducible protein PhoH
AL518_RS19515	COG4535	Mg2 and Co2 transporter CorC
AL518_RS19520	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AL518_RS19535	COG0765	amino acid transport
AL518_RS19540	COG0765	amino acid transport
AL518_RS19545	COG1126	abc transporter atp-binding protein
AL518_RS19550	COG1957	nucleoside hydrolase
AL518_RS19555	COG1957	nucleoside hydrolase
AL518_RS19560	COG2888	peptidyl-tyrosine sulfation
AL518_RS19565	COG0495	leucyl-tRNA aminoacylation
AL518_RS19575	COG1466	dna polymerase III delta subunit
AL518_RS19580	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AL518_RS19585	COG0799	negative regulation of ribosome biogenesis
AL518_RS19590	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AL518_RS19595	COG0768	penicillin binding
AL518_RS19600	COG0772	Belongs to the SEDS family
AL518_RS19605	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AL518_RS19610	COG1686	Belongs to the peptidase S11 family
AL518_RS19620	COG0321	lipoyl(octanoyl) transferase activity
AL518_RS19640	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AL518_RS19665	COG4989	oxidoreductase activity
AL518_RS19695	COG1454	alcohol dehydrogenase
AL518_RS19710	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL518_RS19715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL518_RS19745	COG2186	Transcriptional regulator
AL518_RS19755	COG0534	Mate efflux family protein
AL518_RS19770	COG1309	transcriptional regulator
AL518_RS19785	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AL518_RS19790	COG4771	TonB-dependent receptor
AL518_RS19800	COG0814	amino acid
AL518_RS19815	COG2453	phosphatase
AL518_RS19815	COG0671	phosphoesterase, PA-phosphatase related
AL518_RS19820	COG2267	carboxylic ester hydrolase activity
AL518_RS19830	COG4589	Belongs to the CDS family
AL518_RS19835	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AL518_RS19865	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AL518_RS19870	COG1690	Belongs to the RtcB family
AL518_RS19885	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AL518_RS19890	COG1012	belongs to the aldehyde dehydrogenase family
AL518_RS19895	COG2501	S4 domain
AL518_RS19905	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AL518_RS19910	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL518_RS19915	COG1484	DNA-dependent DNA replication
AL518_RS19925	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AL518_RS19930	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AL518_RS19935	COG3706	GGDEF domain
AL518_RS19940	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AL518_RS19945	COG4181	ATPase activity
AL518_RS19950	COG2755	lipolytic protein G-D-S-L family
AL518_RS19955	COG0300	oxidoreductase activity
AL518_RS19960	COG3118	belongs to the thioredoxin family
AL518_RS19980	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AL518_RS19985	COG2986	histidine ammonia-lyase
AL518_RS19995	COG1126	abc transporter atp-binding protein
AL518_RS20000	COG0765	amino acid transport
AL518_RS20010	COG2841	Protein conserved in bacteria
AL518_RS20020	COG0504	CTP synthase activity
AL518_RS20025	COG3956	TIGRFAM MazG family protein
AL518_RS20030	COG2030	dehydratase
AL518_RS20030	COG1012	belongs to the aldehyde dehydrogenase family
AL518_RS20035	COG3396	Phenylacetate-CoA oxygenase
AL518_RS20040	COG3460	Phenylacetate-CoA oxygenase
AL518_RS20045	COG3396	Phenylacetate-CoA oxygenase
AL518_RS20050	COG2151	metal-sulfur cluster biosynthetic enzyme
AL518_RS20055	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL518_RS20060	COG1024	Enoyl-CoA hydratase
AL518_RS20065	COG1024	Enoyl-CoA hydratase
AL518_RS20070	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL518_RS20075	COG2050	protein possibly involved in aromatic compounds catabolism
AL518_RS20080	COG0183	Belongs to the thiolase family
AL518_RS20085	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AL518_RS20090	COG3327	negative regulation of DNA-templated transcription, initiation
AL518_RS20095	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AL518_RS20105	COG3706	GGDEF domain
AL518_RS20110	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AL518_RS20115	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AL518_RS20125	COG0736	holo-[acyl-carrier-protein] synthase activity
AL518_RS20130	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AL518_RS20135	COG1381	Involved in DNA repair and RecF pathway recombination
AL518_RS20140	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AL518_RS20150	COG0681	Belongs to the peptidase S26 family
AL518_RS20155	COG0481	GTPase activity
AL518_RS20160	COG3086	response to oxidative stress
AL518_RS20170	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
AL518_RS20180	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AL518_RS20195	COG0513	Belongs to the DEAD box helicase family
AL518_RS20205	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AL518_RS20210	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AL518_RS20220	COG0497	DNA recombination
AL518_RS20225	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL518_RS20235	COG2867	negative regulation of translational initiation
AL518_RS20240	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AL518_RS20260	COG4191	Histidine kinase
AL518_RS20280	COG5301	cellulose 1,4-beta-cellobiosidase activity
AL518_RS20395	COG3772	lysozyme
AL518_RS20415	COG1598	PFAM Uncharacterised protein family UPF0150
AL518_RS20420	COG1724	mRNA binding
AL518_RS20435	COG1403	HNH endonuclease
AL518_RS20440	COG4725	Belongs to the MT-A70-like family
AL518_RS20450	COG4626	Terminase
AL518_RS20450	COG1802	Transcriptional regulator
AL518_RS20490	COG0582	viral genome integration into host DNA
AL518_RS20525	COG1070	Carbohydrate kinase
AL518_RS20530	COG3623	hexulose-6-phosphate isomerase
AL518_RS20535	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL518_RS20540	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL518_RS20555	COG1349	DNA-binding transcription factor activity
AL518_RS20560	COG0235	Class ii aldolase
AL518_RS20575	COG3615	Tellurite resistance protein tehB
AL518_RS20610	COG0738	Major facilitator superfamily
AL518_RS20620	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AL518_RS20625	COG0640	Transcriptional regulator
AL518_RS20635	COG0583	DNA-binding transcription factor activity
AL518_RS20640	COG3539	Fimbrial protein
AL518_RS20700	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AL518_RS20705	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
AL518_RS20710	COG1492	cobalamin metabolic process
AL518_RS20775	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A