locus-tag	class	description
ENC22_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ENC22_RS00020	COG2095	MarC family integral membrane protein
ENC22_RS00025	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ENC22_RS00035	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ENC22_RS00035	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ENC22_RS00045	COG4608	Belongs to the ABC transporter superfamily
ENC22_RS00050	COG0444	Belongs to the ABC transporter superfamily
ENC22_RS00060	COG0747	negative chemotaxis
ENC22_RS00070	COG0583	DNA-binding transcription factor activity
ENC22_RS00080	COG0640	Transcriptional regulator
ENC22_RS00095	COG1283	sodium-dependent phosphate transmembrane transporter activity
ENC22_RS00100	COG2133	pyrroloquinoline quinone binding
ENC22_RS00115	COG0751	glycine-tRNA ligase activity
ENC22_RS00120	COG0752	glycyl-tRNA synthetase alpha subunit
ENC22_RS00135	COG0596	Alpha beta hydrolase
ENC22_RS00140	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ENC22_RS00145	COG0569	domain protein
ENC22_RS00155	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ENC22_RS00160	COG0242	peptide deformylase activity
ENC22_RS00170	COG0758	DNA mediated transformation
ENC22_RS00175	COG0009	L-threonylcarbamoyladenylate synthase
ENC22_RS00185	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ENC22_RS00190	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ENC22_RS00205	COG0071	Belongs to the small heat shock protein (HSP20) family
ENC22_RS00210	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ENC22_RS00215	COG0339	signal peptide processing
ENC22_RS00230	COG0534	Mate efflux family protein
ENC22_RS00235	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ENC22_RS00240	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ENC22_RS00265	COG1612	heme a metabolic process
ENC22_RS00270	COG0109	protoheme IX farnesyltransferase activity
ENC22_RS00275	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ENC22_RS00310	COG0415	Belongs to the DNA photolyase family
ENC22_RS00320	COG0745	RESPONSE REGULATOR receiver
ENC22_RS00325	COG2205	protein histidine kinase activity
ENC22_RS00335	COG1280	lysine exporter protein (LysE YggA)
ENC22_RS00345	COG0435	Glutathione S-transferase
ENC22_RS00380	COG2200	EAL domain
ENC22_RS00395	COG0438	transferase activity, transferring glycosyl groups
ENC22_RS00410	COG0438	transferase activity, transferring glycosyl groups
ENC22_RS00420	COG4447	cellulose binding
ENC22_RS00420	COG5520	Belongs to the glycosyl hydrolase 30 family
ENC22_RS00420	COG3291	Pkd domain containing protein
ENC22_RS00425	COG5297	Belongs to the glycosyl hydrolase family 6
ENC22_RS00430	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ENC22_RS00470	COG0572	uridine kinase
ENC22_RS00495	COG0375	protein maturation
ENC22_RS00505	COG3259	Nickel-dependent hydrogenase
ENC22_RS00515	COG3383	formate dehydrogenase (NAD+) activity
ENC22_RS00520	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ENC22_RS00525	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ENC22_RS00550	COG0515	serine threonine protein kinase
ENC22_RS00555	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ENC22_RS00590	COG2356	endonuclease I
ENC22_RS00600	COG1028	Short-chain dehydrogenase reductase Sdr
ENC22_RS00615	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
ENC22_RS00620	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ENC22_RS00650	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ENC22_RS00665	COG2022	thiamine diphosphate biosynthetic process
ENC22_RS00670	COG0352	thiamine-phosphate diphosphorylase activity
ENC22_RS00675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ENC22_RS00680	COG1132	(ABC) transporter
ENC22_RS00715	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ENC22_RS00715	COG0617	tRNA 3'-terminal CCA addition
ENC22_RS00715	COG0517	IMP dehydrogenase activity
ENC22_RS00725	COG0678	peroxiredoxin activity
ENC22_RS00725	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ENC22_RS00730	COG0724	RNA recognition motif
ENC22_RS00740	COG0514	ATP-dependent DNA helicase (RecQ)
ENC22_RS00745	COG1174	glycine betaine transport
ENC22_RS00750	COG1125	glycine betaine transport
ENC22_RS00755	COG1174	glycine betaine transport
ENC22_RS00760	COG1732	Glycine betaine
ENC22_RS00790	COG0430	RNA-3'-phosphate cyclase activity
ENC22_RS00795	COG1690	Belongs to the RtcB family
ENC22_RS00800	COG4650	regulator
ENC22_RS00805	COG1115	amino acid carrier protein
ENC22_RS00810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ENC22_RS00815	COG3541	Predicted nucleotidyltransferase
ENC22_RS00820	COG3706	GGDEF domain
ENC22_RS00825	COG3485	protocatechuate 3,4-dioxygenase
ENC22_RS00885	COG0023	Translation Initiation Factor
ENC22_RS00895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ENC22_RS00950	COG0366	Alpha amylase catalytic
ENC22_RS00960	COG1653	transport
ENC22_RS00975	COG0366	Alpha amylase catalytic
ENC22_RS00985	COG2169	Transcriptional regulator
ENC22_RS00990	COG3785	DNA binding
ENC22_RS00995	COG2205	protein histidine kinase activity
ENC22_RS01005	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ENC22_RS01010	COG2192	nodulation
ENC22_RS01020	COG1741	Belongs to the pirin family
ENC22_RS01030	COG2195	Cleaves the N-terminal amino acid of tripeptides
ENC22_RS01045	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ENC22_RS01050	COG1074	ATP-dependent DNA helicase activity
ENC22_RS01055	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ENC22_RS01075	COG1100	Small GTP-binding protein
ENC22_RS01085	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ENC22_RS01110	COG0842	Transport permease protein
ENC22_RS01115	COG1131	(ABC) transporter
ENC22_RS01130	COG0709	Synthesizes selenophosphate from selenide and ATP
ENC22_RS01135	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
ENC22_RS01190	COG1335	isochorismatase
ENC22_RS01200	COG0840	transmembrane signaling receptor activity
ENC22_RS01210	COG1091	dTDP-4-dehydrorhamnose reductase activity
ENC22_RS01240	COG0714	Associated with various cellular activities
ENC22_RS01260	COG0366	Alpha amylase catalytic
ENC22_RS01265	COG1215	transferase activity, transferring glycosyl groups
ENC22_RS01270	COG3769	mannosylglycerate metabolic process
ENC22_RS01275	COG2199	diguanylate cyclase activity
ENC22_RS01275	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ENC22_RS01280	COG3706	GGDEF domain
ENC22_RS01280	COG5001	Diguanylate cyclase
ENC22_RS01280	COG4251	negative regulation of phosphorylation
ENC22_RS01280	COG2203	Gaf domain
ENC22_RS01315	COG0488	(ABC) transporter
ENC22_RS01340	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ENC22_RS01365	COG0181	hydroxymethylbilane synthase activity
ENC22_RS01375	COG3275	phosphorelay sensor kinase activity
ENC22_RS01380	COG0165	Argininosuccinate lyase
ENC22_RS01385	COG3072	Adenylate cyclase
ENC22_RS01395	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ENC22_RS01405	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ENC22_RS01420	COG2197	response regulator
ENC22_RS01425	COG2205	protein histidine kinase activity
ENC22_RS01435	COG2205	protein histidine kinase activity
ENC22_RS01435	COG0784	Response regulator, receiver
ENC22_RS01465	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ENC22_RS01490	COG3001	Fructosamine kinase
ENC22_RS01495	COG0604	alcohol dehydrogenase
ENC22_RS01500	COG1388	LysM domain
ENC22_RS01500	COG1376	ErfK ybiS ycfS ynhG family protein
ENC22_RS01515	COG2204	response regulator
ENC22_RS01520	COG2234	aminopeptidase activity
ENC22_RS01535	COG2962	Rard protein
ENC22_RS01540	COG0069	glutamate synthase activity
ENC22_RS01560	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
ENC22_RS01570	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ENC22_RS01580	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ENC22_RS01600	COG4580	involved in the transport of maltose and maltodextrins
ENC22_RS01630	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ENC22_RS01695	COG0737	Belongs to the 5'-nucleotidase family
ENC22_RS01720	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ENC22_RS01745	COG0791	NLP P60 protein
ENC22_RS01765	COG0653	protein targeting
ENC22_RS01770	COG1280	lysine exporter protein (LysE YggA)
ENC22_RS01790	COG0469	pyruvate kinase activity
ENC22_RS01805	COG0837	glucose binding
ENC22_RS01810	COG4989	oxidoreductase activity
ENC22_RS01820	COG1794	racemase activity, acting on amino acids and derivatives
ENC22_RS01830	COG0366	Alpha amylase catalytic
ENC22_RS01835	COG2182	Extracellular solute-binding protein
ENC22_RS01840	COG1175	transmembrane transport
ENC22_RS01845	COG3833	ABC-type maltose transport systems, permease component
ENC22_RS01855	COG0724	RNA recognition motif
ENC22_RS01860	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
ENC22_RS01885	COG0745	RESPONSE REGULATOR receiver
ENC22_RS01900	COG0745	RESPONSE REGULATOR receiver
ENC22_RS01905	COG0643	Histidine kinase
ENC22_RS01905	COG2198	Histidine kinase
ENC22_RS01910	COG0835	chemotaxis
ENC22_RS01915	COG0840	transmembrane signaling receptor activity
ENC22_RS01920	COG0840	transmembrane signaling receptor activity
ENC22_RS01925	COG0840	transmembrane signaling receptor activity
ENC22_RS01930	COG0835	chemotaxis
ENC22_RS01945	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ENC22_RS01950	COG2201	protein-glutamate methylesterase activity
ENC22_RS02025	COG2205	protein histidine kinase activity
ENC22_RS02030	COG0519	Catalyzes the synthesis of GMP from XMP
ENC22_RS02040	COG3842	ATPase activity
ENC22_RS02045	COG0366	Alpha amylase catalytic
ENC22_RS02050	COG2909	trisaccharide binding
ENC22_RS02060	COG0471	metal ion transport
ENC22_RS02090	COG0386	Belongs to the glutathione peroxidase family
ENC22_RS02100	COG1832	CoA-binding protein
ENC22_RS02125	COG2203	Gaf domain
ENC22_RS02125	COG5001	Diguanylate cyclase
ENC22_RS02125	COG3706	GGDEF domain
ENC22_RS02125	COG4251	negative regulation of phosphorylation
ENC22_RS02130	COG1846	Transcriptional regulator
ENC22_RS02150	COG1858	cytochrome C peroxidase
ENC22_RS02155	COG0583	DNA-binding transcription factor activity
ENC22_RS02170	COG5265	(ABC) transporter
ENC22_RS02180	COG1054	Belongs to the UPF0176 family
ENC22_RS02185	COG0789	Transcriptional regulator
ENC22_RS02195	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ENC22_RS02205	COG0302	gtp cyclohydrolase
ENC22_RS02230	COG3243	poly(R)-hydroxyalkanoic acid synthase
ENC22_RS02235	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ENC22_RS02240	COG1121	(ABC) transporter
ENC22_RS02245	COG0735	belongs to the Fur family
ENC22_RS02260	COG2201	protein-glutamate methylesterase activity
ENC22_RS02275	COG0840	transmembrane signaling receptor activity
ENC22_RS02295	COG0189	ligase activity
ENC22_RS02305	COG1678	Uncharacterized ACR, COG1678
ENC22_RS02310	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ENC22_RS02320	COG0540	Belongs to the ATCase OTCase family
ENC22_RS02330	COG1555	photosystem II stabilization
ENC22_RS02330	COG3568	Endonuclease Exonuclease Phosphatase
ENC22_RS02355	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ENC22_RS02360	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ENC22_RS02365	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ENC22_RS02370	COG1011	Hydrolase
ENC22_RS02385	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ENC22_RS02400	COG0742	ribosomal rna small subunit methyltransferase
ENC22_RS02405	COG0552	protein localization to endoplasmic reticulum
ENC22_RS02410	COG2884	Cell division ATP-binding protein ftsE
ENC22_RS02415	COG2177	Part of the ABC transporter FtsEX involved in
ENC22_RS02425	COG2084	Dehydrogenase
ENC22_RS02430	COG3622	Belongs to the hyi family
ENC22_RS02435	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ENC22_RS02440	COG0745	RESPONSE REGULATOR receiver
ENC22_RS02445	COG5002	protein histidine kinase activity
ENC22_RS02495	COG1132	(ABC) transporter
ENC22_RS02505	COG0210	DNA helicase
ENC22_RS02535	COG3220	belongs to the UPF0276 family
ENC22_RS02560	COG1250	3-hydroxyacyl-CoA dehydrogenase
ENC22_RS02560	COG1024	Enoyl-CoA hydratase
ENC22_RS02565	COG1024	Enoyl-CoA hydratase
ENC22_RS02570	COG1960	acyl-CoA dehydrogenase activity
ENC22_RS02580	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ENC22_RS02590	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ENC22_RS02610	COG3246	L-lysine catabolic process to acetate
ENC22_RS02620	COG0183	Belongs to the thiolase family
ENC22_RS02625	COG0113	porphobilinogen synthase activity
ENC22_RS02630	COG1611	Belongs to the LOG family
ENC22_RS02635	COG0301	tRNA thio-modification
ENC22_RS02635	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ENC22_RS02655	COG1136	(ABC) transporter
ENC22_RS02655	COG0577	efflux transmembrane transporter activity
ENC22_RS02675	COG2010	Cytochrome c
ENC22_RS02680	COG2010	Cytochrome c
ENC22_RS02705	COG2201	protein-glutamate methylesterase activity
ENC22_RS02720	COG2738	Putative neutral zinc metallopeptidase
ENC22_RS02770	COG1285	pathogenesis
ENC22_RS02785	COG1294	oxidase, subunit
ENC22_RS02790	COG1271	oxidase subunit
ENC22_RS02795	COG2205	protein histidine kinase activity
ENC22_RS02800	COG2204	response regulator
ENC22_RS02815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ENC22_RS02820	COG0601	transmembrane transport
ENC22_RS02825	COG4166	transmembrane transport
ENC22_RS02840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ENC22_RS02865	COG1733	regulation of RNA biosynthetic process
ENC22_RS02880	COG3604	Transcriptional regulator
ENC22_RS02885	COG2207	Transcriptional regulator
ENC22_RS02910	COG1028	Short-chain dehydrogenase reductase Sdr
ENC22_RS02915	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ENC22_RS02975	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ENC22_RS02975	COG2199	diguanylate cyclase activity
ENC22_RS02990	COG1737	Transcriptional regulator
ENC22_RS02995	COG5001	Diguanylate cyclase
ENC22_RS02995	COG3706	GGDEF domain
ENC22_RS02995	COG4251	negative regulation of phosphorylation
ENC22_RS02995	COG2203	Gaf domain
ENC22_RS03000	COG0210	DNA helicase
ENC22_RS03005	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ENC22_RS03015	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ENC22_RS03040	COG0581	inorganic phosphate transmembrane transporter activity
ENC22_RS03045	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ENC22_RS03065	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ENC22_RS03075	COG0537	adenosine 5'-monophosphoramidase activity
ENC22_RS03080	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ENC22_RS03100	COG0668	transmembrane transport
ENC22_RS03105	COG2264	protein methyltransferase activity
ENC22_RS03125	COG0745	RESPONSE REGULATOR receiver
ENC22_RS03140	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ENC22_RS03150	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ENC22_RS03165	COG0189	ligase activity
ENC22_RS03180	COG1946	Acyl-CoA thioesterase
ENC22_RS03190	COG4251	negative regulation of phosphorylation
ENC22_RS03190	COG3706	GGDEF domain
ENC22_RS03190	COG5001	Diguanylate cyclase
ENC22_RS03190	COG2203	Gaf domain
ENC22_RS03215	COG0306	phosphate transporter
ENC22_RS03235	COG2205	protein histidine kinase activity
ENC22_RS03235	COG5002	protein histidine kinase activity
ENC22_RS03235	COG0784	Response regulator, receiver
ENC22_RS03255	COG1320	monovalent cation:proton antiporter activity
ENC22_RS03260	COG2212	antiporter activity
ENC22_RS03265	COG1863	multisubunit Na H antiporter MnhE subunit
ENC22_RS03270	COG0651	ATP synthesis coupled electron transport
ENC22_RS03275	COG1006	Multisubunit Na H antiporter MnhC subunit
ENC22_RS03280	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ENC22_RS03280	COG2111	Na H antiporter
ENC22_RS03290	COG3338	carbonate dehydratase activity
ENC22_RS03295	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ENC22_RS03295	COG5297	Belongs to the glycosyl hydrolase family 6
ENC22_RS03300	COG1028	Short-chain dehydrogenase reductase Sdr
ENC22_RS03305	COG0784	Response regulator, receiver
ENC22_RS03305	COG2205	protein histidine kinase activity
ENC22_RS03305	COG5002	protein histidine kinase activity
ENC22_RS03310	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ENC22_RS03345	COG4932	domain protein
ENC22_RS03345	COG5492	domain, Protein
ENC22_RS03365	COG2050	protein possibly involved in aromatic compounds catabolism
ENC22_RS03385	COG4977	sequence-specific DNA binding
ENC22_RS03385	COG1917	Cupin 2, conserved barrel domain protein
ENC22_RS03400	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ENC22_RS03405	COG5297	Belongs to the glycosyl hydrolase family 6
ENC22_RS03450	COG4585	Histidine kinase
ENC22_RS03465	COG0243	molybdopterin cofactor binding
ENC22_RS03480	COG1012	belongs to the aldehyde dehydrogenase family
ENC22_RS03495	COG4176	ABC-type proline glycine betaine transport system permease component
ENC22_RS03500	COG4175	Glycine betaine
ENC22_RS03515	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
ENC22_RS03520	COG0840	transmembrane signaling receptor activity
ENC22_RS03530	COG2205	protein histidine kinase activity
ENC22_RS03530	COG3437	response regulator, receiver
ENC22_RS03530	COG3850	Histidine kinase
ENC22_RS03530	COG4999	Histidine kinase
ENC22_RS03560	COG0477	Major facilitator Superfamily
ENC22_RS03580	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ENC22_RS03595	COG1917	Cupin 2, conserved barrel domain protein
ENC22_RS03595	COG2207	Transcriptional regulator
ENC22_RS03630	COG0662	Cupin 2, conserved barrel domain protein
ENC22_RS03630	COG2207	Transcriptional regulator
ENC22_RS03645	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ENC22_RS03650	COG0765	amino acid transport
ENC22_RS03655	COG0765	amino acid transport
ENC22_RS03660	COG1126	abc transporter atp-binding protein
ENC22_RS03665	COG4245	von Willebrand factor, type A
ENC22_RS03695	COG0420	3'-5' exonuclease activity
ENC22_RS03700	COG0419	ATPase involved in DNA repair
ENC22_RS03745	COG0583	DNA-binding transcription factor activity
ENC22_RS03750	COG0697	spore germination
ENC22_RS03770	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ENC22_RS03790	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ENC22_RS03795	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ENC22_RS03795	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ENC22_RS03805	COG0356	it plays a direct role in the translocation of protons across the membrane
ENC22_RS03820	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ENC22_RS03825	COG4191	Histidine kinase
ENC22_RS03890	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ENC22_RS03890	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ENC22_RS03920	COG5002	protein histidine kinase activity
ENC22_RS03945	COG0625	glutathione transferase activity
ENC22_RS03955	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
ENC22_RS03990	COG4206	TonB-dependent receptor
ENC22_RS04000	COG1492	cobalamin metabolic process
ENC22_RS04010	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
ENC22_RS04015	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
ENC22_RS04030	COG0784	Response regulator, receiver
ENC22_RS04030	COG5002	protein histidine kinase activity
ENC22_RS04030	COG2205	protein histidine kinase activity
ENC22_RS04040	COG4452	Inner membrane protein CreD
ENC22_RS04050	COG0686	Belongs to the AlaDH PNT family
ENC22_RS04070	COG2308	Evidence 4 Homologs of previously reported genes of
ENC22_RS04070	COG2307	Protein conserved in bacteria
ENC22_RS04080	COG2308	Evidence 4 Homologs of previously reported genes of
ENC22_RS04100	COG3789	protein conserved in bacteria
ENC22_RS04130	COG0076	glutamate decarboxylase activity
ENC22_RS04140	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ENC22_RS04140	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ENC22_RS04145	COG1309	transcriptional regulator
ENC22_RS04150	COG5002	protein histidine kinase activity
ENC22_RS04150	COG5001	Diguanylate cyclase
ENC22_RS04165	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ENC22_RS04180	COG0628	permease
ENC22_RS04190	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ENC22_RS04195	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ENC22_RS04210	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ENC22_RS04230	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ENC22_RS04235	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ENC22_RS04240	COG2003	Belongs to the UPF0758 family
ENC22_RS04245	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ENC22_RS04250	COG0756	dUTP diphosphatase activity
ENC22_RS04260	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ENC22_RS04270	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ENC22_RS04275	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ENC22_RS04275	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ENC22_RS04285	COG5002	protein histidine kinase activity
ENC22_RS04285	COG5001	Diguanylate cyclase
ENC22_RS04295	COG3852	Histidine kinase
ENC22_RS04310	COG1217	gtp-binding protein TYPA
ENC22_RS04320	COG1490	D-aminoacyl-tRNA deacylase activity
ENC22_RS04325	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ENC22_RS04335	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ENC22_RS04350	COG0859	PFAM glycosyl transferase family 9
ENC22_RS04365	COG1442	glycosyl transferase family 8
ENC22_RS04365	COG1216	Glycosyl transferase, family 2
ENC22_RS04370	COG0297	glycogen (starch) synthase activity
ENC22_RS04380	COG0297	glycogen (starch) synthase activity
ENC22_RS04425	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ENC22_RS04435	COG0456	acetyltransferase
ENC22_RS04445	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ENC22_RS04450	COG0084	hydrolase, TatD family'
ENC22_RS04455	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ENC22_RS04460	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ENC22_RS04465	COG0723	plastoquinol--plastocyanin reductase activity
ENC22_RS04470	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ENC22_RS04475	COG2857	Cytochrome c1
ENC22_RS04480	COG0625	glutathione transferase activity
ENC22_RS04485	COG2969	positive regulation of protein catabolic process
ENC22_RS04495	COG0792	nuclease activity
ENC22_RS04515	COG2001	Belongs to the MraZ family
ENC22_RS04520	COG0275	rRNA processing
ENC22_RS04535	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ENC22_RS04540	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ENC22_RS04545	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ENC22_RS04550	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ENC22_RS04555	COG0772	Belongs to the SEDS family
ENC22_RS04560	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ENC22_RS04565	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ENC22_RS04570	COG1181	Belongs to the D-alanine--D-alanine ligase family
ENC22_RS04575	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ENC22_RS04585	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ENC22_RS04590	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ENC22_RS04600	COG0739	heme binding
ENC22_RS04605	COG0653	protein targeting
ENC22_RS04610	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ENC22_RS04615	COG0494	nUDIX hydrolase
ENC22_RS04620	COG0315	cyclic pyranopterin monophosphate synthase activity
ENC22_RS04625	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ENC22_RS04630	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ENC22_RS04635	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ENC22_RS04640	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ENC22_RS04645	COG0142	geranyltranstransferase activity
ENC22_RS04655	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ENC22_RS04660	COG1360	Flagellar Motor Protein
ENC22_RS04675	COG0730	response to heat
ENC22_RS04680	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ENC22_RS04685	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ENC22_RS04695	COG1643	Atp-dependent helicase
ENC22_RS04700	COG0129	dihydroxy-acid dehydratase activity
ENC22_RS04710	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ENC22_RS04720	COG0586	Pfam SNARE associated Golgi protein
ENC22_RS04725	COG3706	GGDEF domain
ENC22_RS04735	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ENC22_RS04740	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ENC22_RS04750	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ENC22_RS04755	COG0768	penicillin binding
ENC22_RS04760	COG0772	Belongs to the SEDS family
ENC22_RS04765	COG2951	lytic endotransglycosylase activity
ENC22_RS04770	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ENC22_RS04775	COG1686	Belongs to the peptidase S11 family
ENC22_RS04780	COG2921	Belongs to the UPF0250 family
ENC22_RS04785	COG0321	lipoyl(octanoyl) transferase activity
ENC22_RS04790	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ENC22_RS04810	COG0784	Response regulator, receiver
ENC22_RS04810	COG0643	Histidine kinase
ENC22_RS04810	COG2198	Histidine kinase
ENC22_RS04815	COG0840	transmembrane signaling receptor activity
ENC22_RS04835	COG0745	RESPONSE REGULATOR receiver
ENC22_RS04840	COG1785	Belongs to the alkaline phosphatase family
ENC22_RS04845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ENC22_RS04850	COG0346	lactoylglutathione lyase activity
ENC22_RS04855	COG0243	molybdopterin cofactor binding
ENC22_RS04860	COG2146	nitrite reductase [NAD(P)H] activity
ENC22_RS04865	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ENC22_RS04870	COG2223	nitrite transmembrane transporter activity
ENC22_RS04875	COG0515	serine threonine protein kinase
ENC22_RS04875	COG2815	serine threonine protein kinase
ENC22_RS04895	COG1126	abc transporter atp-binding protein
ENC22_RS04900	COG0765	amino acid transport
ENC22_RS04905	COG4597	amino acid ABC transporter
ENC22_RS04910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ENC22_RS04915	COG0277	FAD linked oxidase domain protein
ENC22_RS04920	COG0277	FAD linked oxidase domain protein
ENC22_RS04925	COG0247	lactate metabolic process
ENC22_RS04930	COG0531	amino acid
ENC22_RS04935	COG1522	sequence-specific DNA binding
ENC22_RS04950	COG0205	6-phosphofructokinase activity
ENC22_RS04955	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ENC22_RS04990	COG1960	acyl-CoA dehydrogenase activity
ENC22_RS04995	COG3291	Pkd domain containing protein
ENC22_RS05045	COG1024	Enoyl-CoA hydratase
ENC22_RS05060	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ENC22_RS05065	COG0673	inositol 2-dehydrogenase activity
ENC22_RS05075	COG0673	inositol 2-dehydrogenase activity
ENC22_RS05080	COG3718	enzyme involved in inositol metabolism
ENC22_RS05140	COG5002	protein histidine kinase activity
ENC22_RS05140	COG5001	Diguanylate cyclase
ENC22_RS05145	COG0318	PFAM AMP-dependent synthetase and ligase
ENC22_RS05160	COG1024	Enoyl-CoA hydratase
ENC22_RS05165	COG1960	acyl-CoA dehydrogenase activity
ENC22_RS05170	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ENC22_RS05185	COG1309	transcriptional regulator
ENC22_RS05195	COG0745	RESPONSE REGULATOR receiver
ENC22_RS05210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ENC22_RS05215	COG0154	amidase activity
ENC22_RS05220	COG1404	Belongs to the peptidase S8 family
ENC22_RS05310	COG1714	RDD family
ENC22_RS05330	COG0732	type I restriction modification DNA specificity domain
ENC22_RS05335	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
ENC22_RS05345	COG1942	4-Oxalocrotonate Tautomerase
ENC22_RS05360	COG0583	DNA-binding transcription factor activity
ENC22_RS05365	COG3209	COG3209 Rhs family protein
ENC22_RS05470	COG0501	Belongs to the peptidase M48B family
ENC22_RS05485	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ENC22_RS05495	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ENC22_RS05520	COG3795	YCII-related domain
ENC22_RS05535	COG3795	YCII-related domain
ENC22_RS05540	COG4941	Belongs to the sigma-70 factor family
ENC22_RS05545	COG1115	amino acid carrier protein
ENC22_RS05555	COG1215	transferase activity, transferring glycosyl groups
ENC22_RS05560	COG1649	PFAM Uncharacterised BCR, COG1649
ENC22_RS05560	COG0726	polysaccharide deacetylase
ENC22_RS05675	COG2801	Transposase and inactivated derivatives
ENC22_RS05705	COG4650	regulator
ENC22_RS05720	COG0542	response to heat
ENC22_RS05725	COG0542	response to heat
ENC22_RS05745	COG3237	CsbD-like
ENC22_RS05755	COG2235	arginine
ENC22_RS05760	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ENC22_RS05810	COG1280	lysine exporter protein (LysE YggA)
ENC22_RS05845	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ENC22_RS05850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ENC22_RS05855	COG4558	Periplasmic binding protein
ENC22_RS05870	COG4206	TonB-dependent receptor
ENC22_RS05875	COG0745	RESPONSE REGULATOR receiver
ENC22_RS05880	COG2202	Pas domain
ENC22_RS05880	COG2205	protein histidine kinase activity
ENC22_RS05930	COG2824	Alkylphosphonate utilization operon protein PhnA
ENC22_RS05945	COG1842	Phage shock protein A
ENC22_RS05950	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
ENC22_RS05995	COG2814	Major facilitator Superfamily
ENC22_RS06000	COG0640	Transcriptional regulator
ENC22_RS06120	COG0560	Phosphoserine phosphatase
ENC22_RS06120	COG3830	Belongs to the UPF0237 family
ENC22_RS06135	COG1509	lysine 2,3-aminomutase activity
ENC22_RS06140	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ENC22_RS06150	COG0688	phosphatidylethanolamine metabolic process
ENC22_RS06170	COG1360	Flagellar Motor Protein
ENC22_RS06175	COG1162	GTPase activity
ENC22_RS06180	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ENC22_RS06190	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ENC22_RS06190	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ENC22_RS06195	COG0802	atpase or kinase
ENC22_RS06200	COG0860	N-Acetylmuramoyl-L-alanine amidase
ENC22_RS06205	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ENC22_RS06210	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ENC22_RS06215	COG1923	regulation of RNA biosynthetic process
ENC22_RS06220	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ENC22_RS06225	COG0330	HflC and HflK could
ENC22_RS06230	COG0330	HflC and HflK could
ENC22_RS06240	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ENC22_RS06245	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ENC22_RS06255	COG3268	Saccharopine dehydrogenase
ENC22_RS06265	COG0579	oxidoreductase
ENC22_RS06270	COG1040	competence protein
ENC22_RS06275	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ENC22_RS06280	COG0156	8-amino-7-oxononanoate synthase activity
ENC22_RS06285	COG0596	Alpha beta hydrolase
ENC22_RS06290	COG2226	methyltransferase
ENC22_RS06295	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ENC22_RS06310	COG1960	acyl-CoA dehydrogenase activity
ENC22_RS06315	COG1960	acyl-CoA dehydrogenase activity
ENC22_RS06320	COG2356	endonuclease I
ENC22_RS06340	COG0495	leucyl-tRNA aminoacylation
ENC22_RS06350	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ENC22_RS06355	COG4535	Mg2 and Co2 transporter CorC
ENC22_RS06360	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ENC22_RS06365	COG1702	phosphate starvation-inducible protein PhoH
ENC22_RS06370	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ENC22_RS06385	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ENC22_RS06395	COG0175	sulfate reduction
ENC22_RS06405	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ENC22_RS06410	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ENC22_RS06415	COG0154	amidase activity
ENC22_RS06420	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ENC22_RS06425	COG1077	Cell shape determining protein MreB Mrl
ENC22_RS06430	COG1792	Involved in formation and maintenance of cell shape
ENC22_RS06435	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ENC22_RS06440	COG0424	maF-like protein
ENC22_RS06445	COG1530	ribonuclease E activity
ENC22_RS06455	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ENC22_RS06460	COG3028	Belongs to the UPF0307 family
ENC22_RS06465	COG2239	Acts as a magnesium transporter
ENC22_RS06470	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ENC22_RS06475	COG1660	Displays ATPase and GTPase activities
ENC22_RS06495	COG1137	ATPase activity
ENC22_RS06510	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ENC22_RS06520	COG1127	ABC transporter
ENC22_RS06525	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ENC22_RS06545	COG5007	Belongs to the BolA IbaG family
ENC22_RS06550	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ENC22_RS06555	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ENC22_RS06560	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ENC22_RS06565	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ENC22_RS06570	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ENC22_RS06585	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ENC22_RS06590	COG0183	Belongs to the thiolase family
ENC22_RS06605	COG0204	Acyl-transferase
ENC22_RS06640	COG5002	protein histidine kinase activity
ENC22_RS06640	COG0784	Response regulator, receiver
ENC22_RS06640	COG2205	protein histidine kinase activity
ENC22_RS06650	COG1720	tRNA m6t6A37 methyltransferase activity
ENC22_RS06665	COG0237	dephospho-CoA kinase activity
ENC22_RS06695	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ENC22_RS06705	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ENC22_RS06765	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ENC22_RS06775	COG1393	Belongs to the ArsC family
ENC22_RS06780	COG0436	Aminotransferase
ENC22_RS06790	COG0024	Methionine aminopeptidase
ENC22_RS06795	COG0052	Belongs to the universal ribosomal protein uS2 family
ENC22_RS06800	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ENC22_RS06805	COG0528	UMP kinase activity
ENC22_RS06810	COG0233	cytoplasmic translational termination
ENC22_RS06815	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ENC22_RS06825	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ENC22_RS06840	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
ENC22_RS06845	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ENC22_RS06850	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ENC22_RS06855	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ENC22_RS06860	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ENC22_RS06865	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ENC22_RS06875	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ENC22_RS06880	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ENC22_RS06890	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ENC22_RS06910	COG0314	molybdopterin synthase activity
ENC22_RS06915	COG0746	molybdenum cofactor guanylyltransferase activity
ENC22_RS06930	COG1067	ATP-dependent peptidase activity
ENC22_RS06935	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ENC22_RS06950	COG0739	heme binding
ENC22_RS06960	COG4191	Histidine kinase
ENC22_RS06965	COG2988	succinylglutamate desuccinylase activity
ENC22_RS06970	COG4160	amino acid transport
ENC22_RS06980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ENC22_RS07005	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ENC22_RS07010	COG0527	aspartate kinase activity
ENC22_RS07015	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ENC22_RS07035	COG3630	sodium ion export across plasma membrane
ENC22_RS07045	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
ENC22_RS07070	COG1677	Flagellar hook-basal body complex protein FliE
ENC22_RS07105	COG0745	RESPONSE REGULATOR receiver
ENC22_RS07145	COG1987	bacterial-type flagellum assembly
ENC22_RS07155	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ENC22_RS07190	COG0643	Histidine kinase
ENC22_RS07190	COG0784	Response regulator, receiver
ENC22_RS07190	COG2198	Histidine kinase
ENC22_RS07195	COG2201	protein-glutamate methylesterase activity
ENC22_RS07200	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ENC22_RS07210	COG1192	Involved in chromosome partitioning
ENC22_RS07220	COG0835	chemotaxis
ENC22_RS07265	COG4566	intracellular signal transduction
ENC22_RS07270	COG4191	Histidine kinase
ENC22_RS07280	COG0402	S-adenosylhomocysteine deaminase activity
ENC22_RS07285	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ENC22_RS07295	COG1846	Transcriptional regulator
ENC22_RS07300	COG2814	Major facilitator Superfamily
ENC22_RS07305	COG1028	Short-chain dehydrogenase reductase Sdr
ENC22_RS07325	COG1595	DNA-templated transcription, initiation
ENC22_RS07375	COG4669	(LipO)protein
ENC22_RS07390	COG0454	-acetyltransferase
ENC22_RS07430	COG4792	protein secretion
ENC22_RS07435	COG4791	protein targeting
ENC22_RS07440	COG4794	Type iii secretion
ENC22_RS07445	COG4790	Type iii secretion
ENC22_RS07570	COG2197	response regulator
ENC22_RS07575	COG2937	Belongs to the GPAT DAPAT family
ENC22_RS07580	COG1131	(ABC) transporter
ENC22_RS07600	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ENC22_RS07615	COG1073	alpha beta
ENC22_RS07625	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ENC22_RS07635	COG2205	protein histidine kinase activity
ENC22_RS07635	COG0784	Response regulator, receiver
ENC22_RS07645	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ENC22_RS07655	COG3123	guanosine phosphorylase activity
ENC22_RS07670	COG1690	Belongs to the RtcB family
ENC22_RS07710	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ENC22_RS07735	COG1024	Enoyl-CoA hydratase
ENC22_RS07765	COG2840	Smr protein MutS2
ENC22_RS07795	COG0746	molybdenum cofactor guanylyltransferase activity
ENC22_RS07805	COG0431	NADPH-dependent FMN reductase
ENC22_RS07820	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ENC22_RS07830	COG5001	Diguanylate cyclase
ENC22_RS07830	COG5002	protein histidine kinase activity
ENC22_RS07840	COG2267	carboxylic ester hydrolase activity
ENC22_RS07870	COG0745	RESPONSE REGULATOR receiver
ENC22_RS07880	COG0271	Belongs to the BolA IbaG family
ENC22_RS07885	COG0009	L-threonylcarbamoyladenylate synthase
ENC22_RS07895	COG2925	Exonuclease
ENC22_RS07900	COG1025	Belongs to the peptidase M16 family
ENC22_RS07910	COG1028	Short-chain dehydrogenase reductase Sdr
ENC22_RS07915	COG4221	oxidoreductase activity
ENC22_RS07920	COG0450	alkyl hydroperoxide reductase
ENC22_RS07925	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ENC22_RS07930	COG0418	dihydroorotase activity
ENC22_RS07940	COG0137	argininosuccinate synthase activity
ENC22_RS07950	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ENC22_RS07950	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ENC22_RS07955	COG2154	pterin-4-alpha-carbinolamine dehydratase
ENC22_RS07960	COG0788	formyltetrahydrofolate deformylase activity
ENC22_RS07965	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ENC22_RS07965	COG0517	IMP dehydrogenase activity
ENC22_RS07965	COG0617	tRNA 3'-terminal CCA addition
ENC22_RS07975	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ENC22_RS07985	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ENC22_RS07990	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ENC22_RS08000	COG0776	regulation of translation
ENC22_RS08015	COG0284	orotidine-5'-phosphate decarboxylase activity
ENC22_RS08025	COG0436	Aminotransferase
ENC22_RS08060	COG0167	dihydroorotate dehydrogenase activity
ENC22_RS08065	COG3130	regulation of translation
ENC22_RS08070	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ENC22_RS08070	COG0116	Belongs to the methyltransferase superfamily
ENC22_RS08100	COG1362	aminopeptidase activity
ENC22_RS08115	COG0589	response to stress
ENC22_RS08135	COG4181	ATPase activity
ENC22_RS08140	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ENC22_RS08175	COG1570	exodeoxyribonuclease VII activity
ENC22_RS08185	COG0519	Catalyzes the synthesis of GMP from XMP
ENC22_RS08185	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ENC22_RS08210	COG1309	transcriptional regulator
ENC22_RS08215	COG3437	response regulator, receiver
ENC22_RS08230	COG0784	Response regulator, receiver
ENC22_RS08235	COG4251	negative regulation of phosphorylation
ENC22_RS08255	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ENC22_RS08260	COG0217	transcriptional regulatory protein
ENC22_RS08265	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ENC22_RS08270	COG0632	four-way junction helicase activity
ENC22_RS08275	COG2255	four-way junction helicase activity
ENC22_RS08280	COG0824	Thioesterase
ENC22_RS08300	COG5616	cAMP biosynthetic process
ENC22_RS08300	COG0823	Involved in the tonB-independent uptake of proteins
ENC22_RS08305	COG2885	chlorophyll binding
ENC22_RS08325	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ENC22_RS08345	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ENC22_RS08350	COG2716	regulation of RNA biosynthetic process
ENC22_RS08365	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ENC22_RS08380	COG0288	reversible hydration of carbon dioxide
ENC22_RS08385	COG0521	Mo-molybdopterin cofactor biosynthetic process
ENC22_RS08390	COG0303	'Molybdopterin
ENC22_RS08420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ENC22_RS08425	COG1408	metallophosphoesterase
ENC22_RS08435	COG0318	PFAM AMP-dependent synthetase and ligase
ENC22_RS08450	COG2815	serine threonine protein kinase
ENC22_RS08450	COG0515	serine threonine protein kinase
ENC22_RS08460	COG2095	MarC family integral membrane protein
ENC22_RS08470	COG2207	Transcriptional regulator
ENC22_RS08485	COG1881	PFAM PEBP family protein
ENC22_RS08500	COG0673	inositol 2-dehydrogenase activity
ENC22_RS08520	COG0583	DNA-binding transcription factor activity
ENC22_RS08525	COG1234	tRNA 3'-trailer cleavage
ENC22_RS08550	COG1942	4-Oxalocrotonate Tautomerase
ENC22_RS08555	COG0477	Major facilitator Superfamily
ENC22_RS08565	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ENC22_RS08575	COG0745	RESPONSE REGULATOR receiver
ENC22_RS08595	COG3540	Alkaline phosphatase
ENC22_RS08605	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ENC22_RS08610	COG1404	Belongs to the peptidase S8 family
ENC22_RS08615	COG1522	sequence-specific DNA binding
ENC22_RS08620	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ENC22_RS08685	COG1088	dTDP-glucose 4,6-dehydratase activity
ENC22_RS08690	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ENC22_RS08695	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ENC22_RS08700	COG2089	acid synthase
ENC22_RS08705	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ENC22_RS08715	COG1083	cytidylyl-transferase
ENC22_RS08720	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ENC22_RS08735	COG1028	Short-chain dehydrogenase reductase Sdr
ENC22_RS08745	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ENC22_RS08750	COG0107	imidazoleglycerol-phosphate synthase activity
ENC22_RS08785	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ENC22_RS08795	COG0123	including yeast histone deacetylase and acetoin utilization protein
ENC22_RS08800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ENC22_RS08800	COG0045	succinate-CoA ligase (ADP-forming) activity
ENC22_RS08800	COG1042	CoA-binding domain protein
ENC22_RS08805	COG2974	May be involved in recombination
ENC22_RS08810	COG2272	Belongs to the type-B carboxylesterase lipase family
ENC22_RS08840	COG1272	protein, Hemolysin III
ENC22_RS08845	COG3384	dioxygenase
ENC22_RS08850	COG2259	Doxx family
ENC22_RS08855	COG0583	DNA-binding transcription factor activity
ENC22_RS08860	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ENC22_RS08870	COG3022	response to hydroperoxide
ENC22_RS08885	COG1609	Transcriptional regulator
ENC22_RS08915	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ENC22_RS08920	COG3360	Dodecin
ENC22_RS08945	COG2304	oxidoreductase activity
ENC22_RS08965	COG0714	Associated with various cellular activities
ENC22_RS09000	COG0442	prolyl-tRNA aminoacylation
ENC22_RS09015	COG1090	epimerase
ENC22_RS09040	COG0835	chemotaxis
ENC22_RS09040	COG0784	Response regulator, receiver
ENC22_RS09045	COG0633	Ferredoxin
ENC22_RS09045	COG3217	Mosc domain protein beta barrel domain protein
ENC22_RS09050	COG0488	(ABC) transporter
ENC22_RS09060	COG0589	response to stress
ENC22_RS09075	COG1024	Enoyl-CoA hydratase
ENC22_RS09075	COG1250	3-hydroxyacyl-CoA dehydrogenase
ENC22_RS09080	COG0183	Belongs to the thiolase family
ENC22_RS09095	COG2084	Dehydrogenase
ENC22_RS09110	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ENC22_RS09115	COG1053	succinate dehydrogenase
ENC22_RS09120	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ENC22_RS09140	COG0045	succinate-CoA ligase (ADP-forming) activity
ENC22_RS09150	COG0180	Tryptophanyl-tRNA synthetase
ENC22_RS09160	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ENC22_RS09175	COG3239	Fatty acid desaturase
ENC22_RS09190	COG1196	nuclear chromosome segregation
ENC22_RS09195	COG3115	cell septum assembly
ENC22_RS09200	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ENC22_RS09215	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
ENC22_RS09215	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ENC22_RS09220	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ENC22_RS09225	COG5001	Diguanylate cyclase
ENC22_RS09225	COG2203	Gaf domain
ENC22_RS09225	COG3706	GGDEF domain
ENC22_RS09225	COG4251	negative regulation of phosphorylation
ENC22_RS09250	COG0835	chemotaxis
ENC22_RS09250	COG0784	Response regulator, receiver
ENC22_RS09275	COG2855	membrane
ENC22_RS09280	COG0583	DNA-binding transcription factor activity
ENC22_RS09285	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ENC22_RS09305	COG1278	Cold shock
ENC22_RS09310	COG0513	Belongs to the DEAD box helicase family
ENC22_RS09315	COG0513	Belongs to the DEAD box helicase family
ENC22_RS09345	COG1696	Membrane protein involved in D-alanine export
ENC22_RS09355	COG1216	Glycosyl transferase, family 2
ENC22_RS09365	COG5039	Polysaccharide pyruvyl transferase
ENC22_RS09370	COG1215	transferase activity, transferring glycosyl groups
ENC22_RS09375	COG1216	Glycosyl transferase, family 2
ENC22_RS09375	COG0463	Glycosyl transferase, family 2
ENC22_RS09390	COG0438	transferase activity, transferring glycosyl groups
ENC22_RS09410	COG1596	polysaccharide export
ENC22_RS09430	COG0277	FAD linked oxidase domain protein
ENC22_RS09440	COG0515	serine threonine protein kinase
ENC22_RS09440	COG2815	serine threonine protein kinase
ENC22_RS09455	COG5002	protein histidine kinase activity
ENC22_RS09475	COG1131	(ABC) transporter
ENC22_RS09480	COG0659	secondary active sulfate transmembrane transporter activity
ENC22_RS09485	COG0564	pseudouridine synthase activity
ENC22_RS09495	COG0840	transmembrane signaling receptor activity
ENC22_RS09525	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ENC22_RS09535	COG0640	Transcriptional regulator
ENC22_RS09550	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ENC22_RS09585	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ENC22_RS09595	COG3706	GGDEF domain
ENC22_RS09600	COG1879	ABC-type sugar transport system periplasmic component
ENC22_RS09640	COG5001	Diguanylate cyclase
ENC22_RS09650	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ENC22_RS09680	COG0277	FAD linked oxidase domain protein
ENC22_RS09685	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ENC22_RS09690	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ENC22_RS09695	COG0745	RESPONSE REGULATOR receiver
ENC22_RS09700	COG1666	GTP binding
ENC22_RS09715	COG1028	Short-chain dehydrogenase reductase Sdr
ENC22_RS09725	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ENC22_RS09730	COG0459	protein refolding
ENC22_RS09750	COG0501	Belongs to the peptidase M48B family
ENC22_RS09755	COG1704	LemA family
ENC22_RS09760	COG5001	Diguanylate cyclase
ENC22_RS09760	COG3300	MHYT domain
ENC22_RS09825	COG4977	sequence-specific DNA binding
ENC22_RS09830	COG1902	pentaerythritol trinitrate reductase activity
ENC22_RS09830	COG0446	pyridine nucleotide-disulphide oxidoreductase
ENC22_RS09850	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ENC22_RS09855	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ENC22_RS09860	COG0705	Rhomboid family
ENC22_RS09875	COG0308	aminopeptidase N
ENC22_RS09895	COG2358	TRAP transporter, solute receptor (TAXI family
ENC22_RS09905	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ENC22_RS09915	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ENC22_RS09920	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ENC22_RS09925	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ENC22_RS09930	COG0072	phenylalanine-tRNA ligase activity
ENC22_RS09930	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ENC22_RS09935	COG0776	regulation of translation
ENC22_RS09955	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
ENC22_RS09960	COG5001	Diguanylate cyclase
ENC22_RS09960	COG2203	Gaf domain
ENC22_RS09960	COG4251	negative regulation of phosphorylation
ENC22_RS09960	COG3706	GGDEF domain
ENC22_RS09975	COG2203	Gaf domain
ENC22_RS09975	COG4251	negative regulation of phosphorylation
ENC22_RS09975	COG5001	Diguanylate cyclase
ENC22_RS09975	COG3706	GGDEF domain
ENC22_RS09980	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ENC22_RS10005	COG0477	Major facilitator Superfamily
ENC22_RS10035	COG1803	Methylglyoxal synthase
ENC22_RS10045	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ENC22_RS10055	COG0702	epimerase
ENC22_RS10060	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ENC22_RS10075	COG2350	Protein conserved in bacteria
ENC22_RS10080	COG2917	probably involved in intracellular septation
ENC22_RS10085	COG0613	PHP domain protein
ENC22_RS10100	COG1530	ribonuclease E activity
ENC22_RS10105	COG0564	pseudouridine synthase activity
ENC22_RS10110	COG0546	phosphoglycolate phosphatase activity
ENC22_RS10115	COG0616	signal peptide processing
ENC22_RS10115	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ENC22_RS10120	COG0424	maF-like protein
ENC22_RS10130	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ENC22_RS10135	COG0416	fatty acid biosynthetic process
ENC22_RS10140	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ENC22_RS10150	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ENC22_RS10155	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ENC22_RS10160	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ENC22_RS10165	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ENC22_RS10180	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ENC22_RS10185	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ENC22_RS10190	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ENC22_RS10195	COG0215	cysteine-tRNA ligase activity
ENC22_RS10200	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ENC22_RS10225	COG0544	peptidyl-prolyl cis-trans isomerase activity
ENC22_RS10230	COG0740	serine-type endopeptidase activity
ENC22_RS10235	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ENC22_RS10240	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ENC22_RS10255	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ENC22_RS10285	COG0484	heat shock protein binding
ENC22_RS10295	COG0037	tRNA processing
ENC22_RS10305	COG1012	belongs to the aldehyde dehydrogenase family
ENC22_RS10340	COG2217	Heavy metal translocating P-type atpase
ENC22_RS10350	COG0348	domain, Protein
ENC22_RS10355	COG2010	Cytochrome c
ENC22_RS10370	COG3278	Belongs to the heme-copper respiratory oxidase family
ENC22_RS10380	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
ENC22_RS10390	COG0425	Belongs to the sulfur carrier protein TusA family
ENC22_RS10400	COG4232	protein-disulfide reductase activity
ENC22_RS10405	COG3101	peptidyl-lysine hydroxylation
ENC22_RS10415	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ENC22_RS10430	COG0501	Belongs to the peptidase M48B family
ENC22_RS10455	COG0436	Aminotransferase
ENC22_RS10460	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ENC22_RS10470	COG0386	Belongs to the glutathione peroxidase family
ENC22_RS10475	COG1846	Transcriptional regulator
ENC22_RS10495	COG1744	ABC transporter substrate-binding protein PnrA-like
ENC22_RS10500	COG3845	ABC transporter
ENC22_RS10505	COG4603	Belongs to the binding-protein-dependent transport system permease family
ENC22_RS10510	COG1079	Belongs to the binding-protein-dependent transport system permease family
ENC22_RS10545	COG2224	Isocitrate lyase
ENC22_RS10575	COG2153	protein acetylation
ENC22_RS10580	COG2850	peptidyl-arginine hydroxylation
ENC22_RS10590	COG2915	High frequency lysogenization protein hflD homolog
ENC22_RS10595	COG0482	sulfurtransferase activity
ENC22_RS10615	COG1278	Cold shock
ENC22_RS10620	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ENC22_RS10625	COG0542	response to heat
ENC22_RS10630	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ENC22_RS10635	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ENC22_RS10640	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ENC22_RS10645	COG0492	ferredoxin-NADP+ reductase activity
ENC22_RS10650	COG0714	Associated with various cellular activities
ENC22_RS10655	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ENC22_RS10660	COG2957	Belongs to the agmatine deiminase family
ENC22_RS10675	COG4591	ABC-type transport system involved in lipoprotein release permease component
ENC22_RS10680	COG1136	(ABC) transporter
ENC22_RS10685	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ENC22_RS10690	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ENC22_RS10705	COG3344	reverse transcriptase
ENC22_RS10740	COG0740	serine-type endopeptidase activity
ENC22_RS10750	COG1555	photosystem II stabilization
ENC22_RS10770	COG0250	Participates in transcription elongation, termination and antitermination
ENC22_RS10800	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ENC22_RS10805	COG0367	asparagine synthase
ENC22_RS10815	COG1132	(ABC) transporter
ENC22_RS10835	COG0367	asparagine synthase
ENC22_RS10840	COG1083	cytidylyl-transferase
ENC22_RS10845	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ENC22_RS10850	COG2089	acid synthase
ENC22_RS10855	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ENC22_RS10860	COG3562	capsule polysaccharide
ENC22_RS10870	COG4106	trans-aconitate 2-methyltransferase activity
ENC22_RS10900	COG0367	asparagine synthase
ENC22_RS10905	COG0297	glycogen (starch) synthase activity
ENC22_RS10905	COG0438	transferase activity, transferring glycosyl groups
ENC22_RS10910	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ENC22_RS10920	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ENC22_RS10925	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ENC22_RS10940	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ENC22_RS10965	COG0438	transferase activity, transferring glycosyl groups
ENC22_RS10975	COG0662	Cupin 2, conserved barrel domain protein
ENC22_RS10975	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
ENC22_RS10980	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
ENC22_RS10990	COG0084	hydrolase, TatD family'
ENC22_RS11015	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ENC22_RS11020	COG2814	Major facilitator Superfamily
ENC22_RS11030	COG3243	poly(R)-hydroxyalkanoic acid synthase
ENC22_RS11040	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ENC22_RS11045	COG0066	3-isopropylmalate dehydratase activity
ENC22_RS11050	COG0473	3-isopropylmalate dehydrogenase activity
ENC22_RS11070	COG0135	phosphoribosylanthranilate isomerase activity
ENC22_RS11080	COG0159	tryptophan synthase activity
ENC22_RS11085	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ENC22_RS11090	COG0285	dihydrofolate synthase activity
ENC22_RS11100	COG1286	toxin biosynthetic process
ENC22_RS11120	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ENC22_RS11125	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ENC22_RS11130	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ENC22_RS11135	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ENC22_RS11140	COG1648	precorrin-2 dehydrogenase activity
ENC22_RS11140	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ENC22_RS11150	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ENC22_RS11175	COG0840	transmembrane signaling receptor activity
ENC22_RS11180	COG3300	MHYT domain
ENC22_RS11180	COG5001	Diguanylate cyclase
ENC22_RS11220	COG1879	ABC-type sugar transport system periplasmic component
ENC22_RS11225	COG1129	ABC transporter
ENC22_RS11230	COG1172	Belongs to the binding-protein-dependent transport system permease family
ENC22_RS11235	COG1063	alcohol dehydrogenase
ENC22_RS11250	COG1858	cytochrome C peroxidase
ENC22_RS11275	COG0583	DNA-binding transcription factor activity
ENC22_RS11280	COG0697	spore germination
ENC22_RS11285	COG1522	sequence-specific DNA binding
ENC22_RS11325	COG1024	Enoyl-CoA hydratase
ENC22_RS11370	COG0443	Heat shock 70 kDa protein
ENC22_RS11390	COG0659	secondary active sulfate transmembrane transporter activity
ENC22_RS11395	COG0589	response to stress
ENC22_RS11400	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ENC22_RS11425	COG4172	Belongs to the ABC transporter superfamily
ENC22_RS11430	COG4239	(ABC) transporter, permease
ENC22_RS11435	COG4174	ABC transporter (Permease)
ENC22_RS11440	COG4166	transmembrane transport
ENC22_RS11450	COG0741	lytic transglycosylase activity
ENC22_RS11450	COG1388	LysM domain
ENC22_RS11455	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ENC22_RS11465	COG0328	RNA-DNA hybrid ribonuclease activity
ENC22_RS11470	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ENC22_RS11475	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ENC22_RS11495	COG0616	signal peptide processing
ENC22_RS11500	COG0604	alcohol dehydrogenase
ENC22_RS11515	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ENC22_RS11530	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ENC22_RS11530	COG0316	Belongs to the HesB IscA family
ENC22_RS11535	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ENC22_RS11540	COG2920	part of a sulfur-relay system
ENC22_RS11550	COG2923	Belongs to the DsrF TusC family
ENC22_RS11555	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ENC22_RS11575	COG0673	inositol 2-dehydrogenase activity
ENC22_RS11580	COG2205	protein histidine kinase activity
ENC22_RS11585	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ENC22_RS11600	COG4251	negative regulation of phosphorylation
ENC22_RS11605	COG0745	RESPONSE REGULATOR receiver
ENC22_RS11610	COG5001	Diguanylate cyclase
ENC22_RS11610	COG5002	protein histidine kinase activity
ENC22_RS11615	COG4771	TonB-dependent receptor
ENC22_RS11620	COG1028	Short-chain dehydrogenase reductase Sdr
ENC22_RS11690	COG2801	Transposase and inactivated derivatives
ENC22_RS11815	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ENC22_RS11835	COG0322	excinuclease ABC activity
ENC22_RS11845	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ENC22_RS11845	COG3153	acetyltransferase
ENC22_RS11890	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ENC22_RS11910	COG4191	Histidine kinase
ENC22_RS11915	COG2204	response regulator
ENC22_RS11920	COG2204	response regulator
ENC22_RS11925	COG4191	Histidine kinase
ENC22_RS11940	COG2197	response regulator
ENC22_RS11945	COG2223	nitrite transmembrane transporter activity
ENC22_RS11965	COG0175	sulfate reduction
ENC22_RS11975	COG3850	Histidine kinase
ENC22_RS11980	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ENC22_RS11985	COG1140	nitrate reductase beta subunit
ENC22_RS11990	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
ENC22_RS11995	COG2181	nitrate reductase activity
ENC22_RS12005	COG0579	oxidoreductase
ENC22_RS12025	COG2815	serine threonine protein kinase
ENC22_RS12025	COG0515	serine threonine protein kinase
ENC22_RS12030	COG2223	nitrite transmembrane transporter activity
ENC22_RS12050	COG1115	amino acid carrier protein
ENC22_RS12065	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ENC22_RS12070	COG2801	Transposase and inactivated derivatives
ENC22_RS12090	COG5002	protein histidine kinase activity
ENC22_RS12100	COG2814	Major facilitator Superfamily
ENC22_RS12120	COG0500	methyltransferase
ENC22_RS12130	COG2010	Cytochrome c
ENC22_RS12140	COG2207	Transcriptional regulator
ENC22_RS12225	COG0583	DNA-binding transcription factor activity
ENC22_RS12230	COG2130	NADP-dependent
ENC22_RS12265	COG3228	Belongs to the MtfA family
ENC22_RS12290	COG0730	response to heat
ENC22_RS12300	COG0640	Transcriptional regulator
ENC22_RS12310	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ENC22_RS12335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ENC22_RS12340	COG2986	histidine ammonia-lyase
ENC22_RS12345	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ENC22_RS12350	COG0010	Belongs to the arginase family
ENC22_RS12355	COG1228	amidohydrolase
ENC22_RS12360	COG2188	Transcriptional regulator
ENC22_RS12365	COG1201	RNA secondary structure unwinding
ENC22_RS12420	COG0366	Alpha amylase catalytic
ENC22_RS12435	COG2203	Gaf domain
ENC22_RS12435	COG3706	GGDEF domain
ENC22_RS12435	COG4251	negative regulation of phosphorylation
ENC22_RS12435	COG5001	Diguanylate cyclase
ENC22_RS12490	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ENC22_RS12495	COG0745	RESPONSE REGULATOR receiver
ENC22_RS12500	COG2205	protein histidine kinase activity
ENC22_RS12505	COG2200	EAL domain
ENC22_RS12510	COG2081	HI0933 family
ENC22_RS12550	COG0667	Aldo Keto reductase
ENC22_RS12555	COG2207	Transcriptional regulator
ENC22_RS12585	COG3397	chitin binding
ENC22_RS12605	COG0617	tRNA 3'-terminal CCA addition
ENC22_RS12615	COG0398	Pfam SNARE associated Golgi protein
ENC22_RS12625	COG0438	transferase activity, transferring glycosyl groups
ENC22_RS12670	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ENC22_RS12680	COG4770	biotin carboxylase activity
ENC22_RS12685	COG1024	Enoyl-CoA hydratase
ENC22_RS12690	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ENC22_RS12695	COG1960	acyl-CoA dehydrogenase activity
ENC22_RS12745	COG3156	type II secretion system protein K
ENC22_RS12755	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
ENC22_RS12770	COG5002	protein histidine kinase activity
ENC22_RS12770	COG2205	protein histidine kinase activity
ENC22_RS12770	COG0784	Response regulator, receiver
ENC22_RS12780	COG4771	TonB-dependent receptor
ENC22_RS12810	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ENC22_RS12815	COG1605	Chorismate mutase
ENC22_RS12830	COG1280	lysine exporter protein (LysE YggA)
ENC22_RS12930	COG0583	DNA-binding transcription factor activity
ENC22_RS12950	COG1404	Belongs to the peptidase S8 family
ENC22_RS13010	COG0110	maltose O-acetyltransferase activity
ENC22_RS13040	COG0488	(ABC) transporter
ENC22_RS13085	COG0583	DNA-binding transcription factor activity
ENC22_RS13090	COG0509	glycine decarboxylation via glycine cleavage system
ENC22_RS13095	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ENC22_RS13095	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ENC22_RS13100	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ENC22_RS13105	COG1760	l-serine dehydratase
ENC22_RS13110	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ENC22_RS13125	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ENC22_RS13135	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ENC22_RS13140	COG0835	chemotaxis
ENC22_RS13155	COG0840	transmembrane signaling receptor activity
ENC22_RS13165	COG2201	protein-glutamate methylesterase activity
ENC22_RS13295	COG4774	siderophore transport
ENC22_RS13295	COG1629	transport
ENC22_RS13300	COG2382	esterase
ENC22_RS13375	COG0210	DNA helicase
ENC22_RS13400	COG1111	helicase
ENC22_RS13400	COG1205	dead DEAH box helicase
ENC22_RS13440	COG2259	Doxx family
ENC22_RS13450	COG1120	ATPase activity
ENC22_RS13455	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ENC22_RS13460	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ENC22_RS13465	COG0477	Major facilitator Superfamily
ENC22_RS13470	COG4592	Periplasmic binding protein
ENC22_RS13480	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ENC22_RS13485	COG1979	alcohol dehydrogenase
ENC22_RS13495	COG0187	DNA topoisomerase II activity
ENC22_RS13560	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ENC22_RS13575	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ENC22_RS13580	COG1126	abc transporter atp-binding protein
ENC22_RS13585	COG0765	amino acid transport
ENC22_RS13590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ENC22_RS13610	COG3811	Belongs to the UPF0386 family
ENC22_RS13700	COG1733	regulation of RNA biosynthetic process
ENC22_RS13705	COG1028	Short-chain dehydrogenase reductase Sdr
ENC22_RS13735	COG0189	ligase activity
ENC22_RS13745	COG2202	Pas domain
ENC22_RS13745	COG2205	protein histidine kinase activity
ENC22_RS13750	COG4251	negative regulation of phosphorylation
ENC22_RS13750	COG3706	GGDEF domain
ENC22_RS13750	COG2203	Gaf domain
ENC22_RS13750	COG5001	Diguanylate cyclase
ENC22_RS13765	COG0643	Histidine kinase
ENC22_RS13765	COG2198	Histidine kinase
ENC22_RS13770	COG0840	transmembrane signaling receptor activity
ENC22_RS13775	COG0835	chemotaxis
ENC22_RS13785	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ENC22_RS13790	COG2201	protein-glutamate methylesterase activity
ENC22_RS13800	COG0784	Response regulator, receiver
ENC22_RS13800	COG5002	protein histidine kinase activity
ENC22_RS13800	COG2205	protein histidine kinase activity
ENC22_RS13810	COG0530	calcium, potassium:sodium antiporter activity
ENC22_RS13825	COG0583	DNA-binding transcription factor activity
ENC22_RS13835	COG0019	diaminopimelate decarboxylase activity
ENC22_RS13840	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ENC22_RS13850	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ENC22_RS13855	COG0022	dehydrogenase e1 component
ENC22_RS13860	COG0508	dehydrogenase complex catalyzes the overall conversion of
ENC22_RS13865	COG0515	serine threonine protein kinase
ENC22_RS13915	COG2119	membrane
ENC22_RS13985	COG3021	interspecies interaction between organisms
ENC22_RS14010	COG0443	Heat shock 70 kDa protein
ENC22_RS14020	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ENC22_RS14025	COG5001	Diguanylate cyclase
ENC22_RS14025	COG3300	MHYT domain
ENC22_RS14055	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ENC22_RS14080	COG0745	RESPONSE REGULATOR receiver
ENC22_RS14135	COG0010	Belongs to the arginase family
ENC22_RS14140	COG0535	radical SAM domain protein
ENC22_RS14180	COG0745	RESPONSE REGULATOR receiver
ENC22_RS14185	COG5002	protein histidine kinase activity
ENC22_RS14250	COG2885	chlorophyll binding
ENC22_RS14255	COG3437	response regulator, receiver
ENC22_RS14255	COG0784	Response regulator, receiver
ENC22_RS14260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ENC22_RS14260	COG4191	Histidine kinase
ENC22_RS14265	COG3047	cAMP biosynthetic process
ENC22_RS14280	COG4191	Histidine kinase
ENC22_RS14285	COG0778	Nitroreductase
ENC22_RS14355	COG0583	DNA-binding transcription factor activity
ENC22_RS14490	COG1609	Transcriptional regulator
ENC22_RS14495	COG3265	gluconokinase activity
ENC22_RS14510	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ENC22_RS14525	COG1309	transcriptional regulator
ENC22_RS14535	COG3209	COG3209 Rhs family protein
ENC22_RS14550	COG1959	2 iron, 2 sulfur cluster binding
ENC22_RS14555	COG1902	pentaerythritol trinitrate reductase activity
ENC22_RS14570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ENC22_RS14615	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ENC22_RS14620	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ENC22_RS14660	COG3263	regulation of cellular component size
ENC22_RS14690	COG0644	oxidoreductase
ENC22_RS14715	COG2226	methyltransferase
ENC22_RS14825	COG4792	protein secretion
ENC22_RS14830	COG4791	protein targeting
ENC22_RS14835	COG4794	Type iii secretion
ENC22_RS14840	COG4790	Type iii secretion
ENC22_RS14885	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ENC22_RS14905	COG4789	Type iii secretion
ENC22_RS14980	COG1175	transmembrane transport
ENC22_RS14985	COG0395	ABC-type sugar transport system, permease component
ENC22_RS14990	COG3842	ATPase activity
ENC22_RS14995	COG1234	tRNA 3'-trailer cleavage
ENC22_RS15000	COG0483	inositol monophosphate 1-phosphatase activity
ENC22_RS15005	COG1609	Transcriptional regulator
ENC22_RS15055	COG0406	alpha-ribazole phosphatase activity
ENC22_RS15105	COG3552	Protein containing von Willebrand factor type A (VWA) domain
ENC22_RS15110	COG2425	protein containing a von Willebrand factor type A (vWA) domain
ENC22_RS15115	COG0714	Associated with various cellular activities
ENC22_RS15120	COG3831	ATPase activity
ENC22_RS15150	COG0583	DNA-binding transcription factor activity
ENC22_RS15155	COG0625	glutathione transferase activity
ENC22_RS15160	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ENC22_RS15160	COG1017	nitric oxide dioxygenase activity
ENC22_RS15185	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ENC22_RS15190	COG3118	belongs to the thioredoxin family
ENC22_RS15195	COG4232	protein-disulfide reductase activity
ENC22_RS15235	COG1733	regulation of RNA biosynthetic process
ENC22_RS15280	COG0183	Belongs to the thiolase family
ENC22_RS15285	COG1250	3-hydroxyacyl-CoA dehydrogenase
ENC22_RS15285	COG1024	Enoyl-CoA hydratase
ENC22_RS15295	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ENC22_RS15320	COG0297	glycogen (starch) synthase activity
ENC22_RS15395	COG1250	3-hydroxyacyl-CoA dehydrogenase
ENC22_RS15430	COG4615	Cyclic peptide transporter
ENC22_RS15450	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ENC22_RS15460	COG1960	acyl-CoA dehydrogenase activity
ENC22_RS15465	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ENC22_RS15470	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ENC22_RS15475	COG0840	transmembrane signaling receptor activity
ENC22_RS15480	COG0840	transmembrane signaling receptor activity
ENC22_RS15505	COG3586	endonuclease activity
ENC22_RS15515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ENC22_RS15540	COG1028	Short-chain dehydrogenase reductase Sdr
ENC22_RS15540	COG3321	synthase
ENC22_RS15540	COG4221	oxidoreductase activity
ENC22_RS15540	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ENC22_RS15555	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ENC22_RS15560	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ENC22_RS15560	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ENC22_RS15560	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ENC22_RS15560	COG1028	Short-chain dehydrogenase reductase Sdr
ENC22_RS15560	COG3321	synthase
ENC22_RS15570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ENC22_RS15570	COG1028	Short-chain dehydrogenase reductase Sdr
ENC22_RS15570	COG0300	oxidoreductase activity
ENC22_RS15570	COG0318	PFAM AMP-dependent synthetase and ligase
ENC22_RS15570	COG3321	synthase
ENC22_RS15625	COG0601	transmembrane transport
ENC22_RS15630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ENC22_RS15650	COG2249	NAD(P)H dehydrogenase (quinone) activity
ENC22_RS15670	COG0795	lipopolysaccharide-transporting ATPase activity
ENC22_RS15675	COG5002	protein histidine kinase activity
ENC22_RS15695	COG3335	DDE superfamily endonuclease
ENC22_RS15710	COG0840	transmembrane signaling receptor activity
ENC22_RS15745	COG4106	trans-aconitate 2-methyltransferase activity
ENC22_RS15755	COG1070	Carbohydrate kinase
ENC22_RS15775	COG0753	catalase activity
ENC22_RS15790	COG1840	ABC-type Fe3 transport system, periplasmic component
ENC22_RS15795	COG3842	ATPase activity
ENC22_RS15805	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ENC22_RS15810	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ENC22_RS15820	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ENC22_RS15850	COG0583	DNA-binding transcription factor activity
ENC22_RS15860	COG0813	purine-nucleoside phosphorylase activity
ENC22_RS15865	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
ENC22_RS15870	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ENC22_RS15885	COG0546	phosphoglycolate phosphatase activity
ENC22_RS15895	COG0596	Alpha beta hydrolase
ENC22_RS15925	COG0069	glutamate synthase activity
ENC22_RS15935	COG0693	protein deglycase activity
ENC22_RS15945	COG4572	Cation transport regulator
ENC22_RS15950	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ENC22_RS15965	COG0071	Belongs to the small heat shock protein (HSP20) family
ENC22_RS15970	COG0071	Belongs to the small heat shock protein (HSP20) family
ENC22_RS15985	COG1917	Cupin 2, conserved barrel domain protein
ENC22_RS15985	COG4977	sequence-specific DNA binding
ENC22_RS16005	COG0604	alcohol dehydrogenase
ENC22_RS16025	COG2818	Glycosylase
ENC22_RS16115	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
ENC22_RS16115	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
ENC22_RS16135	COG0604	alcohol dehydrogenase
ENC22_RS16135	COG1028	Short-chain dehydrogenase reductase Sdr
ENC22_RS16135	COG3321	synthase
ENC22_RS16145	COG1028	Short-chain dehydrogenase reductase Sdr
ENC22_RS16150	COG1846	Transcriptional regulator
ENC22_RS16155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ENC22_RS16195	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
ENC22_RS16230	COG0625	glutathione transferase activity
ENC22_RS16285	COG0488	(ABC) transporter
ENC22_RS16325	COG0515	serine threonine protein kinase
ENC22_RS16330	COG2116	formate transmembrane transporter activity
ENC22_RS16355	COG3710	Transcriptional regulator
ENC22_RS16380	COG3938	Belongs to the proline racemase family
ENC22_RS16395	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ENC22_RS16400	COG1012	belongs to the aldehyde dehydrogenase family
ENC22_RS16465	COG2205	protein histidine kinase activity
ENC22_RS16465	COG4999	Histidine kinase
ENC22_RS16465	COG3850	Histidine kinase
ENC22_RS16465	COG3437	response regulator, receiver
ENC22_RS16470	COG3706	GGDEF domain
ENC22_RS16505	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ENC22_RS16510	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ENC22_RS16575	COG2197	response regulator
ENC22_RS16635	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ENC22_RS16775	COG3023	N-Acetylmuramoyl-L-alanine amidase
ENC22_RS16780	COG2003	Belongs to the UPF0758 family
ENC22_RS16830	COG1395	domain, Protein
ENC22_RS16960	COG2169	Transcriptional regulator
ENC22_RS16960	COG1917	Cupin 2, conserved barrel domain protein
ENC22_RS16980	COG0305	Participates in initiation and elongation during chromosome replication
ENC22_RS17010	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ENC22_RS17025	COG2226	methyltransferase
ENC22_RS17060	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
ENC22_RS17070	COG0297	glycogen (starch) synthase activity
ENC22_RS17085	COG1215	transferase activity, transferring glycosyl groups
ENC22_RS17110	COG0110	maltose O-acetyltransferase activity
ENC22_RS17130	COG0438	transferase activity, transferring glycosyl groups
ENC22_RS17135	COG0463	Glycosyl transferase, family 2
ENC22_RS17140	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ENC22_RS17175	COG1366	Belongs to the anti-sigma-factor antagonist family
ENC22_RS17205	COG2204	response regulator
ENC22_RS17210	COG2204	response regulator
ENC22_RS17245	COG1609	Transcriptional regulator
ENC22_RS17250	COG2207	Transcriptional regulator
ENC22_RS17265	COG3597	protein domain associated with
ENC22_RS17310	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ENC22_RS17370	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ENC22_RS17375	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
ENC22_RS17425	COG2814	Major facilitator Superfamily
ENC22_RS17480	COG3706	GGDEF domain
ENC22_RS17480	COG2203	Gaf domain
ENC22_RS17480	COG5001	Diguanylate cyclase
ENC22_RS17480	COG4251	negative regulation of phosphorylation
ENC22_RS17510	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ENC22_RS17555	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ENC22_RS17560	COG0318	PFAM AMP-dependent synthetase and ligase
ENC22_RS17565	COG1960	acyl-CoA dehydrogenase activity
ENC22_RS17655	COG2192	nodulation
ENC22_RS17710	COG1522	sequence-specific DNA binding
ENC22_RS17720	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ENC22_RS17730	COG0793	Belongs to the peptidase S41A family
ENC22_RS17745	COG2815	serine threonine protein kinase
ENC22_RS17745	COG0515	serine threonine protein kinase
ENC22_RS17790	COG3209	COG3209 Rhs family protein
ENC22_RS17820	COG1104	cysteine desulfurase activity
ENC22_RS17825	COG2062	phosphohistidine phosphatase, SixA
ENC22_RS17830	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ENC22_RS17855	COG0708	Exodeoxyribonuclease III
ENC22_RS17880	COG0204	Acyl-transferase
ENC22_RS17895	COG4191	Histidine kinase
ENC22_RS17900	COG2204	response regulator
ENC22_RS17920	COG0471	metal ion transport
ENC22_RS17920	COG3273	potassium ion transport
ENC22_RS17945	COG0529	Catalyzes the synthesis of activated sulfate
ENC22_RS17960	COG0463	Glycosyl transferase, family 2
ENC22_RS17960	COG1216	Glycosyl transferase, family 2
ENC22_RS17965	COG0463	Glycosyl transferase, family 2
ENC22_RS17990	COG2244	polysaccharide biosynthetic process
ENC22_RS17995	COG0438	transferase activity, transferring glycosyl groups
ENC22_RS18015	COG0438	transferase activity, transferring glycosyl groups
ENC22_RS18020	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ENC22_RS18020	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ENC22_RS18040	COG0489	protein tyrosine kinase activity
ENC22_RS18055	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ENC22_RS18060	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ENC22_RS18065	COG2079	MmgE PrpD family protein
ENC22_RS18070	COG0372	Belongs to the citrate synthase family
ENC22_RS18075	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ENC22_RS18085	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ENC22_RS18090	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ENC22_RS18095	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ENC22_RS18100	COG2835	tetraacyldisaccharide 4'-kinase activity
ENC22_RS18105	COG1663	tetraacyldisaccharide 4'-kinase activity
ENC22_RS18110	COG1132	(ABC) transporter
ENC22_RS18115	COG0848	biopolymer transport protein
ENC22_RS18120	COG0811	peptide transport
ENC22_RS18125	COG0658	competence protein
ENC22_RS18135	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ENC22_RS18135	COG1605	Chorismate mutase
ENC22_RS18140	COG0584	glycerophosphoryl diester phosphodiesterase
ENC22_RS18145	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ENC22_RS18155	COG1477	protein flavinylation
ENC22_RS18165	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ENC22_RS18180	COG1805	sodium ion transport
ENC22_RS18185	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ENC22_RS18195	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ENC22_RS18210	COG0668	transmembrane transport
ENC22_RS18215	COG1472	Belongs to the glycosyl hydrolase 3 family
ENC22_RS18220	COG1376	ErfK ybiS ycfS ynhG family protein
ENC22_RS18230	COG0004	ammonium transporteR
ENC22_RS18240	COG0307	riboflavin synthase, alpha
ENC22_RS18255	COG0470	DNA polymerase III
ENC22_RS18290	COG0560	Phosphoserine phosphatase
ENC22_RS18305	COG0583	DNA-binding transcription factor activity
ENC22_RS18310	COG0730	response to heat
ENC22_RS18320	COG1199	ATP-dependent helicase activity
ENC22_RS18330	COG3409	Peptidoglycan-binding domain 1 protein
ENC22_RS18330	COG3267	Type II secretory pathway component ExeA
ENC22_RS18335	COG1752	Esterase of the alpha-beta hydrolase superfamily
ENC22_RS18340	COG2853	Lipoprotein
ENC22_RS18350	COG1643	Atp-dependent helicase
ENC22_RS18365	COG0318	PFAM AMP-dependent synthetase and ligase
ENC22_RS18370	COG2267	carboxylic ester hydrolase activity
ENC22_RS18375	COG2030	dehydratase
ENC22_RS18395	COG0811	peptide transport
ENC22_RS18430	COG0542	response to heat
ENC22_RS18440	COG0121	glutamine amidotransferase
ENC22_RS18455	COG2983	Belongs to the UPF0260 family
ENC22_RS18460	COG3100	YcgL domain-containing protein
ENC22_RS18465	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ENC22_RS18470	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ENC22_RS18475	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ENC22_RS18480	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ENC22_RS18495	COG1214	PFAM Peptidase M22, glycoprotease
ENC22_RS18495	COG0456	acetyltransferase
ENC22_RS18500	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
ENC22_RS18515	COG2951	lytic endotransglycosylase activity
ENC22_RS18555	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ENC22_RS18595	COG0840	transmembrane signaling receptor activity
ENC22_RS18730	COG3713	MltA-interacting MipA family protein
ENC22_RS18760	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ENC22_RS18770	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
ENC22_RS18795	COG0288	reversible hydration of carbon dioxide
ENC22_RS18800	COG2204	response regulator
ENC22_RS18810	COG0784	Response regulator, receiver
ENC22_RS18820	COG4251	negative regulation of phosphorylation
ENC22_RS18835	COG5002	protein histidine kinase activity
ENC22_RS18840	COG0515	serine threonine protein kinase
ENC22_RS18905	COG0583	DNA-binding transcription factor activity
ENC22_RS18945	COG0745	RESPONSE REGULATOR receiver
ENC22_RS18950	COG0784	Response regulator, receiver
ENC22_RS18955	COG0784	Response regulator, receiver
ENC22_RS18955	COG2205	protein histidine kinase activity
ENC22_RS18965	COG4771	TonB-dependent receptor
ENC22_RS18970	COG5001	Diguanylate cyclase
ENC22_RS18970	COG4251	negative regulation of phosphorylation
ENC22_RS18970	COG3706	GGDEF domain
ENC22_RS18970	COG2203	Gaf domain
ENC22_RS18985	COG3604	Transcriptional regulator
ENC22_RS18990	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ENC22_RS19140	COG5002	protein histidine kinase activity
ENC22_RS19145	COG0653	protein targeting
ENC22_RS19150	COG2909	trisaccharide binding
ENC22_RS19170	COG0446	pyridine nucleotide-disulphide oxidoreductase
ENC22_RS19210	COG0583	DNA-binding transcription factor activity
ENC22_RS19215	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ENC22_RS19275	COG2205	protein histidine kinase activity
ENC22_RS19295	COG0745	RESPONSE REGULATOR receiver
ENC22_RS19315	COG1628	Protein of unknown function DUF99
ENC22_RS19355	COG0745	RESPONSE REGULATOR receiver
ENC22_RS19360	COG4191	Histidine kinase
ENC22_RS19365	COG5002	protein histidine kinase activity
ENC22_RS19370	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
ENC22_RS19375	COG0402	S-adenosylhomocysteine deaminase activity
ENC22_RS19380	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ENC22_RS19390	COG1028	Short-chain dehydrogenase reductase Sdr
ENC22_RS19415	COG1138	Cytochrome C-type biogenesis protein
ENC22_RS19420	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
ENC22_RS19440	COG4133	protoheme IX ABC transporter activity
ENC22_RS19460	COG0783	Belongs to the Dps family
ENC22_RS19465	COG0668	transmembrane transport
ENC22_RS19490	COG2989	Protein conserved in bacteria
ENC22_RS19500	COG1597	lipid kinase activity
ENC22_RS19520	COG0583	DNA-binding transcription factor activity
ENC22_RS19560	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ENC22_RS19565	COG1132	(ABC) transporter
ENC22_RS19570	COG2832	Protein of unknown function (DUF454)
ENC22_RS19575	COG2873	o-acetylhomoserine
ENC22_RS19590	COG2010	Cytochrome c
ENC22_RS19600	COG0714	Associated with various cellular activities
ENC22_RS19620	COG3391	amine dehydrogenase activity
ENC22_RS19645	COG0535	radical SAM domain protein
ENC22_RS19660	COG0662	Cupin 2, conserved barrel domain protein
ENC22_RS19675	COG1960	acyl-CoA dehydrogenase activity
ENC22_RS19725	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
ENC22_RS19730	COG0084	hydrolase, TatD family'
ENC22_RS19745	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ENC22_RS19755	COG1160	GTP binding
ENC22_RS19770	COG0124	histidyl-tRNA synthetase
ENC22_RS19775	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ENC22_RS19780	COG1426	Protein conserved in bacteria
ENC22_RS19790	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ENC22_RS19795	COG0105	UTP biosynthetic process
ENC22_RS19800	COG1104	cysteine desulfurase activity
ENC22_RS19810	COG1045	serine acetyltransferase
ENC22_RS19835	COG1862	Preprotein translocase
ENC22_RS19840	COG0343	queuine tRNA-ribosyltransferase activity
ENC22_RS19845	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ENC22_RS19860	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ENC22_RS19865	COG4786	Flagellar basal body rod
ENC22_RS19865	COG1256	bacterial-type flagellum assembly
ENC22_RS19875	COG1706	bacterial-type flagellum-dependent cell motility
ENC22_RS19880	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
ENC22_RS19890	COG4787	bacterial-type flagellum-dependent cell motility
ENC22_RS19900	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ENC22_RS19905	COG1558	bacterial-type flagellum-dependent cell motility
ENC22_RS19910	COG1815	bacterial-type flagellum-dependent cell motility
ENC22_RS19930	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ENC22_RS19930	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ENC22_RS19935	COG0842	Transport permease protein
ENC22_RS19940	COG1131	(ABC) transporter
ENC22_RS19960	COG1840	ABC-type Fe3 transport system, periplasmic component
ENC22_RS19965	COG1178	ABC-type Fe3 transport system permease component
ENC22_RS19970	COG1022	Amp-dependent synthetase and ligase
ENC22_RS19985	COG4120	Belongs to the binding-protein-dependent transport system permease family
ENC22_RS20040	COG0411	ABC transporter
ENC22_RS20060	COG0829	nickel cation binding
ENC22_RS20065	COG0831	urea catabolic process
ENC22_RS20070	COG0832	Belongs to the urease beta subunit family
ENC22_RS20080	COG0804	urea catabolic process
ENC22_RS20085	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
ENC22_RS20090	COG0830	nickel cation binding
ENC22_RS20095	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ENC22_RS20110	COG0259	pyridoxamine-phosphate oxidase activity
ENC22_RS20125	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ENC22_RS20125	COG0519	Catalyzes the synthesis of GMP from XMP
ENC22_RS20130	COG1254	Belongs to the acylphosphatase family
ENC22_RS20145	COG1959	2 iron, 2 sulfur cluster binding
ENC22_RS20220	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ENC22_RS20235	COG0017	Asparaginyl-tRNA synthetase
ENC22_RS20240	COG2226	methyltransferase
ENC22_RS20245	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ENC22_RS20250	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ENC22_RS20260	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ENC22_RS20270	COG0564	pseudouridine synthase activity
ENC22_RS20275	COG2813	Specifically methylates the guanine in position
ENC22_RS20295	COG0729	surface antigen
ENC22_RS20300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ENC22_RS20305	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ENC22_RS20310	COG1280	lysine exporter protein (LysE YggA)
ENC22_RS20315	COG3154	lipid carrier protein
ENC22_RS20320	COG0826	peptidase U32
ENC22_RS20325	COG0826	peptidase U32
ENC22_RS20335	COG3842	ATPase activity
ENC22_RS20340	COG1176	ABC-type spermidine putrescine transport system, permease component I
ENC22_RS20345	COG1177	transmembrane transport
ENC22_RS20350	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ENC22_RS20375	COG0587	DNA-directed DNA polymerase activity
ENC22_RS20405	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ENC22_RS20420	COG0494	nUDIX hydrolase
ENC22_RS20430	COG3323	Protein of unknown function (DUF1653)
ENC22_RS20430	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ENC22_RS20435	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ENC22_RS20435	COG0047	phosphoribosylformylglycinamidine synthase activity
ENC22_RS20440	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
ENC22_RS20445	COG2137	regulation of response to DNA damage stimulus
ENC22_RS20460	COG0183	Belongs to the thiolase family
ENC22_RS20465	COG1024	Enoyl-CoA hydratase
ENC22_RS20465	COG1250	3-hydroxyacyl-CoA dehydrogenase
ENC22_RS20470	COG0793	Belongs to the peptidase S41A family
ENC22_RS20490	COG3291	Pkd domain containing protein
ENC22_RS20500	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ENC22_RS20520	COG0326	Molecular chaperone. Has ATPase activity
ENC22_RS20530	COG0564	pseudouridine synthase activity
ENC22_RS20550	COG2807	transmembrane transport
ENC22_RS20570	COG0676	glucose-6-phosphate 1-epimerase activity
ENC22_RS20600	COG0204	Acyl-transferase
ENC22_RS20605	COG2818	Glycosylase
ENC22_RS20615	COG1132	(ABC) transporter
ENC22_RS20620	COG1132	(ABC) transporter
ENC22_RS20655	COG1181	Belongs to the D-alanine--D-alanine ligase family
ENC22_RS20670	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ENC22_RS20685	COG1028	Short-chain dehydrogenase reductase Sdr
ENC22_RS20725	COG2378	regulation of single-species biofilm formation
ENC22_RS20795	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ENC22_RS20810	COG3181	Tripartite tricarboxylate transporter family receptor
ENC22_RS20820	COG0583	DNA-binding transcription factor activity
ENC22_RS20825	COG0210	DNA helicase
ENC22_RS20835	COG2207	Transcriptional regulator
ENC22_RS20905	COG0393	Putative heavy-metal-binding
ENC22_RS20915	COG1231	oxidoreductase activity
ENC22_RS20920	COG3961	Belongs to the TPP enzyme family
ENC22_RS20940	COG4221	oxidoreductase activity
ENC22_RS20945	COG2267	carboxylic ester hydrolase activity
ENC22_RS20975	COG3209	COG3209 Rhs family protein
ENC22_RS20975	COG3209	COG3209 Rhs family protein
ENC22_RS20995	COG0842	Transport permease protein
ENC22_RS21000	COG0842	Transport permease protein
ENC22_RS21000	COG1129	ABC transporter
ENC22_RS21005	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ENC22_RS21030	COG4953	penicillin-binding protein 1C
ENC22_RS21035	COG2373	Large extracellular alpha-helical protein
ENC22_RS21045	COG0631	protein serine/threonine phosphatase activity
ENC22_RS21050	COG0515	serine threonine protein kinase
ENC22_RS21050	COG2815	serine threonine protein kinase
ENC22_RS21055	COG3724	N-succinylarginine dihydrolase activity
ENC22_RS21060	COG1012	belongs to the aldehyde dehydrogenase family
ENC22_RS21100	COG3647	Membrane
ENC22_RS21115	COG0693	protein deglycase activity
ENC22_RS21135	COG0795	lipopolysaccharide-transporting ATPase activity
ENC22_RS21140	COG0795	lipopolysaccharide-transporting ATPase activity
ENC22_RS21145	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ENC22_RS21160	COG0525	valine-tRNA ligase activity
ENC22_RS21170	COG2096	Adenosyltransferase
ENC22_RS21200	COG3577	Aspartyl protease
ENC22_RS21230	COG1573	uracil-dna glycosylase
ENC22_RS21245	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ENC22_RS21250	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ENC22_RS21260	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ENC22_RS21265	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ENC22_RS21275	COG3977	Valine--pyruvate aminotransferase
ENC22_RS21290	COG0717	Belongs to the dCTP deaminase family
ENC22_RS21295	COG0489	protein tyrosine kinase activity
ENC22_RS21300	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ENC22_RS21300	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ENC22_RS21305	COG4657	Part of a membrane complex involved in electron transport
ENC22_RS21310	COG2878	Part of a membrane complex involved in electron transport
ENC22_RS21315	COG4656	Part of a membrane complex involved in electron transport
ENC22_RS21320	COG4658	electron transport chain
ENC22_RS21330	COG4660	Part of a membrane complex involved in electron transport
ENC22_RS21335	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ENC22_RS21395	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ENC22_RS21400	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ENC22_RS21405	COG0585	pseudouridine synthase activity
ENC22_RS21410	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ENC22_RS21415	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ENC22_RS21420	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ENC22_RS21450	COG0148	phosphopyruvate hydratase activity
ENC22_RS21455	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ENC22_RS21460	COG0504	CTP synthase activity
ENC22_RS21470	COG0037	tRNA processing
ENC22_RS21475	COG0825	malonyl-CoA metabolic process
ENC22_RS21490	COG1393	Belongs to the ArsC family
ENC22_RS21505	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ENC22_RS21540	COG0642	Histidine kinase
ENC22_RS21545	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
ENC22_RS21550	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
ENC22_RS21555	COG0235	Class ii aldolase
ENC22_RS21565	COG1444	tRNA N-acetyltransferase activity
ENC22_RS21575	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ENC22_RS21595	COG0601	transmembrane transport
ENC22_RS21600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ENC22_RS21605	COG0444	Belongs to the ABC transporter superfamily
ENC22_RS21610	COG4608	Belongs to the ABC transporter superfamily
ENC22_RS21615	COG0583	DNA-binding transcription factor activity
ENC22_RS21650	COG2353	YceI-like domain
ENC22_RS21655	COG3038	cytochrome b561
ENC22_RS21665	COG0500	methyltransferase
ENC22_RS21675	COG1968	undecaprenyl-diphosphatase activity
ENC22_RS21680	COG1214	PFAM Peptidase M22, glycoprotease
ENC22_RS21685	COG0563	adenylate kinase activity
ENC22_RS21695	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ENC22_RS21705	COG3956	TIGRFAM MazG family protein
ENC22_RS21710	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ENC22_RS21715	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ENC22_RS21725	COG2205	protein histidine kinase activity
ENC22_RS21725	COG5002	protein histidine kinase activity
ENC22_RS21725	COG0784	Response regulator, receiver
ENC22_RS21730	COG1381	Involved in DNA repair and RecF pathway recombination
ENC22_RS21735	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ENC22_RS21740	COG0571	ribonuclease III activity
ENC22_RS21750	COG0681	Belongs to the peptidase S26 family
ENC22_RS21755	COG0481	GTPase activity
ENC22_RS21760	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ENC22_RS21765	COG3086	response to oxidative stress
ENC22_RS21815	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ENC22_RS21825	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ENC22_RS21840	COG0436	Aminotransferase
ENC22_RS21845	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ENC22_RS21855	COG0335	large ribosomal subunit rRNA binding
ENC22_RS21860	COG0336	Belongs to the RNA methyltransferase TrmD family
ENC22_RS21865	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ENC22_RS21870	COG0228	four-way junction DNA binding
ENC22_RS21875	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ENC22_RS21880	COG4137	Cytochrome C assembly protein
ENC22_RS21885	COG4536	flavin adenine dinucleotide binding
ENC22_RS21905	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ENC22_RS21910	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ENC22_RS21915	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ENC22_RS21920	COG3842	ATPase activity
ENC22_RS21935	COG2205	protein histidine kinase activity
ENC22_RS21940	COG0745	RESPONSE REGULATOR receiver
ENC22_RS21955	COG1047	Peptidyl-prolyl cis-trans
ENC22_RS21965	COG0840	transmembrane signaling receptor activity
ENC22_RS21980	COG0667	Aldo Keto reductase
ENC22_RS21985	COG0438	transferase activity, transferring glycosyl groups
ENC22_RS21995	COG0850	regulation of cytokinetic process
ENC22_RS22000	COG2894	cell division
ENC22_RS22005	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
ENC22_RS22020	COG1309	transcriptional regulator
ENC22_RS22025	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ENC22_RS22030	COG4067	protein conserved in archaea
ENC22_RS22030	COG0189	ligase activity
ENC22_RS22035	COG0415	Belongs to the DNA photolyase family
ENC22_RS22040	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ENC22_RS22045	COG2890	protein-(glutamine-N5) methyltransferase activity
ENC22_RS22050	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ENC22_RS22055	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ENC22_RS22070	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ENC22_RS22080	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ENC22_RS22085	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ENC22_RS22090	COG0193	aminoacyl-tRNA hydrolase activity
ENC22_RS22095	COG0012	GTP binding
ENC22_RS22125	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ENC22_RS22135	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ENC22_RS22140	COG0305	Participates in initiation and elongation during chromosome replication
ENC22_RS22145	COG0359	binds to the 23S rRNA
ENC22_RS22150	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ENC22_RS22155	COG0360	Binds together with S18 to 16S ribosomal RNA
ENC22_RS22165	COG0557	exoribonuclease II activity
ENC22_RS22190	COG4650	regulator
ENC22_RS22195	COG1404	Belongs to the peptidase S8 family
ENC22_RS22205	COG1960	acyl-CoA dehydrogenase activity
ENC22_RS22210	COG0628	permease
ENC22_RS22275	COG0584	glycerophosphoryl diester phosphodiesterase
ENC22_RS22280	COG1024	Enoyl-CoA hydratase
ENC22_RS22290	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ENC22_RS22300	COG3706	GGDEF domain
ENC22_RS22315	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ENC22_RS22325	COG1363	Peptidase, m42
ENC22_RS22330	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ENC22_RS22330	COG0189	ligase activity
ENC22_RS22335	COG0367	asparagine synthase
ENC22_RS22340	COG1846	Transcriptional regulator
ENC22_RS22345	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ENC22_RS22350	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ENC22_RS22355	COG0583	DNA-binding transcription factor activity
ENC22_RS22365	COG0840	transmembrane signaling receptor activity
ENC22_RS22370	COG0179	Fumarylacetoacetate (FAA) hydrolase
ENC22_RS22375	COG0277	FAD linked oxidase domain protein
ENC22_RS22380	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ENC22_RS22385	COG2197	response regulator
ENC22_RS22415	COG0745	RESPONSE REGULATOR receiver
ENC22_RS22420	COG0642	Histidine kinase
ENC22_RS22435	COG0156	8-amino-7-oxononanoate synthase activity
ENC22_RS22440	COG1063	alcohol dehydrogenase
ENC22_RS22470	COG0583	DNA-binding transcription factor activity
ENC22_RS22530	COG4143	(ABC) transporter
ENC22_RS22535	COG1178	ABC-type Fe3 transport system permease component
ENC22_RS22555	COG0390	transport system, permease component
ENC22_RS22565	COG0400	carboxylic ester hydrolase activity
ENC22_RS22625	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ENC22_RS22645	COG0501	Belongs to the peptidase M48B family
ENC22_RS22665	COG2153	protein acetylation
ENC22_RS22760	COG0583	DNA-binding transcription factor activity
ENC22_RS22765	COG0154	amidase activity
ENC22_RS22770	COG3179	chitinase
ENC22_RS22785	COG0417	DNA replication proofreading
ENC22_RS22795	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
ENC22_RS22800	COG3122	Protein conserved in bacteria
ENC22_RS22820	COG1408	metallophosphoesterase
ENC22_RS22860	COG0835	chemotaxis
ENC22_RS22860	COG0784	Response regulator, receiver
ENC22_RS22865	COG2885	chlorophyll binding
ENC22_RS22880	COG0126	phosphoglycerate kinase activity
ENC22_RS22890	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ENC22_RS22900	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ENC22_RS22905	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ENC22_RS22910	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ENC22_RS22915	COG5001	Diguanylate cyclase
ENC22_RS22915	COG3300	MHYT domain
ENC22_RS22925	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ENC22_RS22930	COG4399	Belongs to the UPF0754 family
ENC22_RS22945	COG1295	ribonuclease BN
ENC22_RS22950	COG0432	Pfam Uncharacterised protein family UPF0047
ENC22_RS22960	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ENC22_RS22965	COG3706	GGDEF domain
ENC22_RS22970	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ENC22_RS22975	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
ENC22_RS22980	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ENC22_RS23005	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ENC22_RS23010	COG1917	Cupin 2, conserved barrel domain protein
ENC22_RS23015	COG5285	phytanoyl-CoA dioxygenase
ENC22_RS23020	COG1752	Esterase of the alpha-beta hydrolase superfamily
ENC22_RS23030	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ENC22_RS23035	COG3012	SEC-C Motif Domain Protein
ENC22_RS23055	COG0330	HflC and HflK could
ENC22_RS23080	COG1012	belongs to the aldehyde dehydrogenase family
ENC22_RS23115	COG2770	Histidine kinase
ENC22_RS23115	COG3437	response regulator, receiver
ENC22_RS23120	COG2766	serine protein kinase
ENC22_RS23130	COG2719	SpoVR family
ENC22_RS23155	COG1177	transmembrane transport
ENC22_RS23160	COG1176	ABC-type spermidine putrescine transport system, permease component I
ENC22_RS23165	COG3842	ATPase activity
ENC22_RS23170	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ENC22_RS23200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ENC22_RS23225	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
ENC22_RS23230	COG2909	trisaccharide binding
ENC22_RS23265	COG2205	protein histidine kinase activity
ENC22_RS23295	COG2205	protein histidine kinase activity
ENC22_RS23305	COG2204	response regulator
ENC22_RS23340	COG3085	chromosome segregation
ENC22_RS23350	COG0719	Fe-S assembly protein
ENC22_RS23355	COG0396	ATPase activity
ENC22_RS23360	COG0719	Fe-S assembly protein
ENC22_RS23365	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ENC22_RS23370	COG0316	Belongs to the HesB IscA family
ENC22_RS23375	COG2151	metal-sulfur cluster biosynthetic enzyme
ENC22_RS23380	COG2166	iron-sulfur cluster assembly
ENC22_RS23395	COG0431	NADPH-dependent FMN reductase
ENC22_RS23400	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ENC22_RS23415	COG3011	Protein conserved in bacteria
ENC22_RS23455	COG1120	ATPase activity
ENC22_RS23465	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ENC22_RS23470	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ENC22_RS23470	COG1522	sequence-specific DNA binding
ENC22_RS23475	COG2313	pseudouridylate synthase activity
ENC22_RS23480	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
ENC22_RS23495	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ENC22_RS23630	COG3604	Transcriptional regulator
ENC22_RS23645	COG1017	nitric oxide dioxygenase activity
ENC22_RS23645	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ENC22_RS23660	COG0617	tRNA 3'-terminal CCA addition
ENC22_RS23670	COG2113	Glycine betaine
ENC22_RS23675	COG4176	ABC-type proline glycine betaine transport system permease component
ENC22_RS23680	COG4175	Glycine betaine
ENC22_RS23685	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ENC22_RS23690	COG1764	response to oxidative stress
ENC22_RS23695	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ENC22_RS23705	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ENC22_RS23710	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ENC22_RS23715	COG4942	peptidase
ENC22_RS23715	COG4942	peptidase
ENC22_RS23720	COG0793	Belongs to the peptidase S41A family
ENC22_RS23725	COG2861	carbohydrate metabolic process
ENC22_RS23735	COG0107	imidazoleglycerol-phosphate synthase activity
ENC22_RS23740	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ENC22_RS23745	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ENC22_RS23750	COG0131	Imidazoleglycerol-phosphate dehydratase
ENC22_RS23765	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
ENC22_RS23830	COG0500	methyltransferase
ENC22_RS23845	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ENC22_RS23845	COG0574	Belongs to the PEP-utilizing enzyme family
ENC22_RS23860	COG1741	Belongs to the pirin family
ENC22_RS23865	COG2977	Belongs to the P-Pant transferase superfamily
ENC22_RS23885	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ENC22_RS23890	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ENC22_RS23945	COG0583	DNA-binding transcription factor activity
ENC22_RS23950	COG0384	phenazine biosynthesis protein PhzF
ENC22_RS24005	COG1840	ABC-type Fe3 transport system, periplasmic component
ENC22_RS24070	COG3552	Protein containing von Willebrand factor type A (VWA) domain
ENC22_RS24075	COG2425	protein containing a von Willebrand factor type A (vWA) domain
ENC22_RS24080	COG0714	Associated with various cellular activities
ENC22_RS24110	COG1278	Cold shock
ENC22_RS24115	COG0557	exoribonuclease II activity
ENC22_RS24135	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ENC22_RS24135	COG2169	Transcriptional regulator
ENC22_RS24175	COG3706	GGDEF domain
ENC22_RS24205	COG3118	belongs to the thioredoxin family
ENC22_RS24225	COG0523	cobalamin synthesis protein
ENC22_RS24250	COG0583	DNA-binding transcription factor activity
ENC22_RS24255	COG0583	DNA-binding transcription factor activity
ENC22_RS24260	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ENC22_RS24265	COG1929	Belongs to the glycerate kinase type-1 family
ENC22_RS24270	COG1846	Transcriptional regulator
ENC22_RS24305	COG0395	ABC-type sugar transport system, permease component
ENC22_RS24335	COG1686	Belongs to the peptidase S11 family
ENC22_RS24390	COG0702	epimerase
ENC22_RS24435	COG2186	Transcriptional regulator
ENC22_RS24440	COG0247	lactate metabolic process
ENC22_RS24445	COG1139	Iron-sulfur cluster binding protein
ENC22_RS24475	COG0577	efflux transmembrane transporter activity
ENC22_RS24475	COG1136	(ABC) transporter
ENC22_RS24480	COG1136	(ABC) transporter
ENC22_RS24480	COG0577	efflux transmembrane transporter activity
ENC22_RS24495	COG3118	belongs to the thioredoxin family
ENC22_RS24505	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ENC22_RS24550	COG1185	polyribonucleotide nucleotidyltransferase activity
ENC22_RS24555	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ENC22_RS24560	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ENC22_RS24565	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ENC22_RS24570	COG3064	Membrane
ENC22_RS24570	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ENC22_RS24575	COG0195	Participates in both transcription termination and antitermination
ENC22_RS24575	COG2251	uridine kinase activity
ENC22_RS24580	COG0779	Required for maturation of 30S ribosomal subunits
ENC22_RS24595	COG0149	triose-phosphate isomerase activity
ENC22_RS24600	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ENC22_RS24605	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ENC22_RS24610	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ENC22_RS24615	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ENC22_RS24625	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ENC22_RS24635	COG0505	Belongs to the CarA family
ENC22_RS24640	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ENC22_RS24645	COG0484	heat shock protein binding
ENC22_RS24650	COG0443	Heat shock 70 kDa protein
ENC22_RS24655	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ENC22_RS24660	COG0497	DNA recombination
ENC22_RS24675	COG2914	Belongs to the UPF0125 (RnfH) family
ENC22_RS24690	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ENC22_RS24705	COG1136	(ABC) transporter
ENC22_RS24705	COG0577	efflux transmembrane transporter activity
ENC22_RS24710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ENC22_RS24765	COG1741	Belongs to the pirin family
ENC22_RS24770	COG0583	DNA-binding transcription factor activity
ENC22_RS24780	COG0583	DNA-binding transcription factor activity
ENC22_RS24790	COG1902	pentaerythritol trinitrate reductase activity
ENC22_RS24810	COG0583	DNA-binding transcription factor activity
ENC22_RS24815	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ENC22_RS24835	COG1609	Transcriptional regulator
ENC22_RS24840	COG4211	Belongs to the binding-protein-dependent transport system permease family
ENC22_RS24845	COG1129	ABC transporter
ENC22_RS24860	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ENC22_RS24865	COG3962	Belongs to the TPP enzyme family
ENC22_RS24900	COG2249	NAD(P)H dehydrogenase (quinone) activity
ENC22_RS24905	COG0583	DNA-binding transcription factor activity
ENC22_RS24950	COG1294	oxidase, subunit
ENC22_RS24955	COG4890	Cyd operon protein YbgT
ENC22_RS25005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ENC22_RS25010	COG0601	transmembrane transport
ENC22_RS25035	COG0848	biopolymer transport protein
ENC22_RS25040	COG0811	peptide transport
ENC22_RS25045	COG0811	peptide transport
ENC22_RS25080	COG0124	histidyl-tRNA synthetase
ENC22_RS25090	COG0018	arginyl-trna synthetase
ENC22_RS25130	COG1309	transcriptional regulator
ENC22_RS25145	COG1079	Belongs to the binding-protein-dependent transport system permease family
ENC22_RS25150	COG4603	Belongs to the binding-protein-dependent transport system permease family
ENC22_RS25155	COG3845	ABC transporter
ENC22_RS25165	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ENC22_RS25175	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ENC22_RS25180	COG4266	Belongs to the allantoicase family
ENC22_RS25190	COG2351	hydroxyisourate hydrolase activity
ENC22_RS25200	COG0402	S-adenosylhomocysteine deaminase activity
ENC22_RS25210	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
ENC22_RS25215	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ENC22_RS25245	COG2226	methyltransferase
ENC22_RS25255	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ENC22_RS25260	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ENC22_RS25265	COG0140	phosphoribosyl-ATP diphosphatase activity
ENC22_RS25270	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ENC22_RS25275	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ENC22_RS25290	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ENC22_RS25295	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ENC22_RS25300	COG0006	proline dipeptidase activity
ENC22_RS25325	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ENC22_RS25330	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ENC22_RS25335	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ENC22_RS25340	COG1960	acyl-CoA dehydrogenase activity
ENC22_RS25345	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ENC22_RS25350	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ENC22_RS25350	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ENC22_RS25355	COG1560	Kdo2-lipid A biosynthetic process
ENC22_RS25360	COG0859	PFAM glycosyl transferase family 9
ENC22_RS25365	COG0438	transferase activity, transferring glycosyl groups
ENC22_RS25375	COG0438	transferase activity, transferring glycosyl groups
ENC22_RS25410	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ENC22_RS25415	COG1183	phosphatidylcholine synthase activity
ENC22_RS25420	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ENC22_RS25430	COG0028	Belongs to the TPP enzyme family
ENC22_RS25440	COG0542	response to heat
ENC22_RS25460	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ENC22_RS25460	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ENC22_RS25510	COG4969	Belongs to the N-Me-Phe pilin family
ENC22_RS25515	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ENC22_RS25520	COG1047	Peptidyl-prolyl cis-trans
ENC22_RS25525	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ENC22_RS25530	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ENC22_RS25535	COG0196	riboflavin kinase activity
ENC22_RS25545	COG0268	Binds directly to 16S ribosomal RNA
ENC22_RS25550	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ENC22_RS25555	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ENC22_RS25560	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ENC22_RS25565	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ENC22_RS25570	COG0142	geranyltranstransferase activity
ENC22_RS25580	COG2078	PFAM AMMECR1 domain protein
ENC22_RS25585	COG1355	regulation of microtubule-based process
ENC22_RS25600	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ENC22_RS25610	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ENC22_RS25615	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ENC22_RS25630	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ENC22_RS25630	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ENC22_RS25635	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ENC22_RS25640	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ENC22_RS25645	COG0488	(ABC) transporter
ENC22_RS25655	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ENC22_RS25660	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ENC22_RS25665	COG0493	'glutamate synthase
ENC22_RS25670	COG0070	glutamate synthase
ENC22_RS25670	COG0069	glutamate synthase activity
ENC22_RS25670	COG0067	glutamate synthase
ENC22_RS25680	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ENC22_RS25685	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ENC22_RS25720	COG0281	malic enzyme
ENC22_RS25725	COG0254	rRNA binding
ENC22_RS25730	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ENC22_RS25735	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ENC22_RS25740	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ENC22_RS25745	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ENC22_RS25765	COG0494	nUDIX hydrolase
ENC22_RS25790	COG0509	glycine decarboxylation via glycine cleavage system
ENC22_RS25795	COG3150	esterase
ENC22_RS25800	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ENC22_RS25805	COG3151	Protein conserved in bacteria
ENC22_RS25810	COG0494	nUDIX hydrolase
ENC22_RS25815	COG1538	Outer membrane efflux protein
ENC22_RS25820	COG1519	Transferase
ENC22_RS25830	COG0667	Aldo Keto reductase
ENC22_RS25840	COG2199	diguanylate cyclase activity
ENC22_RS25840	COG2200	EAL domain
ENC22_RS25850	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ENC22_RS25855	COG0511	ligase activity, forming carbon-carbon bonds
ENC22_RS25865	COG2264	protein methyltransferase activity
ENC22_RS25890	COG0138	bifunctional purine biosynthesis protein purh
ENC22_RS25895	COG0151	Belongs to the GarS family
ENC22_RS25905	COG4251	negative regulation of phosphorylation
ENC22_RS25935	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ENC22_RS25940	COG1960	acyl-CoA dehydrogenase activity
ENC22_RS25945	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
ENC22_RS25950	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
ENC22_RS25960	COG0028	Belongs to the TPP enzyme family
ENC22_RS25970	COG1414	Transcriptional regulator
ENC22_RS25970	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ENC22_RS25975	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ENC22_RS25980	COG0156	8-amino-7-oxononanoate synthase activity
ENC22_RS25985	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ENC22_RS25990	COG3321	synthase
ENC22_RS26005	COG0778	Nitroreductase
ENC22_RS26050	COG2205	protein histidine kinase activity
ENC22_RS26055	COG0745	RESPONSE REGULATOR receiver
ENC22_RS26105	COG0367	asparagine synthase
ENC22_RS26110	COG1132	(ABC) transporter
ENC22_RS26185	COG0662	Cupin 2, conserved barrel domain protein
ENC22_RS26185	COG2207	Transcriptional regulator
ENC22_RS26205	COG3842	ATPase activity
ENC22_RS26210	COG0395	ABC-type sugar transport system, permease component
ENC22_RS26215	COG1175	transmembrane transport
ENC22_RS26240	COG1280	lysine exporter protein (LysE YggA)
ENC22_RS26250	COG3132	Protein of unknown function, DUF480
ENC22_RS26265	COG0077	Prephenate dehydratase
ENC22_RS26265	COG1605	Chorismate mutase
ENC22_RS26280	COG1309	transcriptional regulator
ENC22_RS26290	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ENC22_RS26295	COG2967	ApaG domain
ENC22_RS26300	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ENC22_RS26305	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ENC22_RS26310	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ENC22_RS26315	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ENC22_RS26325	COG3178	'Phosphotransferase
ENC22_RS26330	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ENC22_RS26345	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ENC22_RS26350	COG0546	phosphoglycolate phosphatase activity
ENC22_RS26355	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
ENC22_RS26400	COG1960	acyl-CoA dehydrogenase activity
ENC22_RS26405	COG0022	dehydrogenase e1 component
ENC22_RS26420	COG0512	Glutamine amidotransferase of anthranilate synthase
ENC22_RS26425	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ENC22_RS26430	COG0134	indole-3-glycerol-phosphate synthase activity
ENC22_RS26435	COG0583	DNA-binding transcription factor activity
ENC22_RS26455	COG1765	OsmC-like protein
ENC22_RS26460	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
ENC22_RS26470	COG3954	Phosphoribulokinase
ENC22_RS26505	COG2165	general secretion pathway protein
ENC22_RS26515	COG1459	type II secretion system
ENC22_RS26520	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ENC22_RS26530	COG3267	Type II secretory pathway component ExeA
ENC22_RS26530	COG3409	Peptidoglycan-binding domain 1 protein
ENC22_RS26565	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ENC22_RS26570	COG1045	serine acetyltransferase
ENC22_RS26585	COG0318	PFAM AMP-dependent synthetase and ligase
ENC22_RS26590	COG1215	transferase activity, transferring glycosyl groups
ENC22_RS26600	COG0529	Catalyzes the synthesis of activated sulfate
ENC22_RS26690	COG2814	Major facilitator Superfamily
ENC22_RS26700	COG0203	ribosomal protein L17
ENC22_RS26705	COG0202	RNA polymerase activity
ENC22_RS26710	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ENC22_RS26715	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ENC22_RS26720	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ENC22_RS26725	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ENC22_RS26735	COG0200	Binds to the 23S rRNA
ENC22_RS26740	COG1841	ribosomal large subunit assembly
ENC22_RS26745	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ENC22_RS26750	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ENC22_RS26755	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ENC22_RS26760	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ENC22_RS26765	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ENC22_RS26770	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ENC22_RS26775	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ENC22_RS26780	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ENC22_RS26785	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ENC22_RS26790	COG0255	Belongs to the universal ribosomal protein uL29 family
ENC22_RS26795	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ENC22_RS26800	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ENC22_RS26805	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ENC22_RS26810	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ENC22_RS26815	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ENC22_RS26820	COG0089	rRNA binding
ENC22_RS26825	COG0088	Forms part of the polypeptide exit tunnel
ENC22_RS26830	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ENC22_RS26835	COG0051	transcription antitermination factor activity, RNA binding
ENC22_RS26840	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ENC22_RS26845	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ENC22_RS26850	COG0049	tRNA binding
ENC22_RS26855	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ENC22_RS26860	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ENC22_RS26865	COG0085	RNA polymerase activity
ENC22_RS26870	COG0222	ribosome binding
ENC22_RS26875	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ENC22_RS26880	COG0081	regulation of translation
ENC22_RS26885	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ENC22_RS26905	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ENC22_RS26935	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ENC22_RS26975	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ENC22_RS26980	COG0739	heme binding
ENC22_RS26985	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ENC22_RS26995	COG0316	Belongs to the HesB IscA family
ENC22_RS27010	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ENC22_RS27020	COG1981	membrane
ENC22_RS27025	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ENC22_RS27035	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ENC22_RS27060	COG1489	DNA binding
ENC22_RS27070	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ENC22_RS27075	COG5002	protein histidine kinase activity
ENC22_RS27090	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ENC22_RS27095	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ENC22_RS27100	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ENC22_RS27105	COG0166	Belongs to the GPI family
ENC22_RS27110	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ENC22_RS27115	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ENC22_RS27120	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ENC22_RS27125	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ENC22_RS27130	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ENC22_RS27135	COG1610	YqeY-like protein
ENC22_RS27165	COG3153	acetyltransferase
ENC22_RS27295	COG4695	Portal protein
ENC22_RS27360	COG4974	Belongs to the 'phage' integrase family
ENC22_RS27495	COG0625	glutathione transferase activity
ENC22_RS27500	COG2207	Transcriptional regulator
ENC22_RS27515	COG1012	belongs to the aldehyde dehydrogenase family
ENC22_RS27520	COG1473	amidohydrolase
ENC22_RS27525	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ENC22_RS27530	COG0583	DNA-binding transcription factor activity
ENC22_RS27535	COG1028	Short-chain dehydrogenase reductase Sdr
ENC22_RS27570	COG0741	lytic transglycosylase activity
ENC22_RS27570	COG0739	heme binding
ENC22_RS27570	COG1196	nuclear chromosome segregation
ENC22_RS27580	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
ENC22_RS27585	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ENC22_RS27610	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ENC22_RS27615	COG0583	DNA-binding transcription factor activity
ENC22_RS27620	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ENC22_RS27630	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ENC22_RS27635	COG1758	RNA polymerase activity
ENC22_RS27640	COG0194	GDP metabolic process
ENC22_RS27650	COG0519	Catalyzes the synthesis of GMP from XMP
ENC22_RS27660	COG1012	belongs to the aldehyde dehydrogenase family
ENC22_RS27670	COG0531	amino acid
ENC22_RS27680	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ENC22_RS27725	COG0732	type I restriction modification DNA specificity domain
ENC22_RS27730	COG1121	(ABC) transporter
ENC22_RS27750	COG2856	Zn peptidase
ENC22_RS27775	COG1561	YicC-like family, N-terminal region
ENC22_RS27785	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ENC22_RS27790	COG0708	Exodeoxyribonuclease III
ENC22_RS27795	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ENC22_RS27815	COG3174	membrane
ENC22_RS27820	COG0826	peptidase U32
ENC22_RS27830	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ENC22_RS27870	COG1872	DUF167
ENC22_RS27875	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ENC22_RS27880	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ENC22_RS27885	COG2813	Specifically methylates the guanine in position
ENC22_RS27885	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ENC22_RS27895	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ENC22_RS27900	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ENC22_RS27910	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ENC22_RS27920	COG0606	chelatase, subunit chli
ENC22_RS27930	COG0347	Belongs to the P(II) protein family
ENC22_RS27935	COG0004	ammonium transporteR
ENC22_RS27955	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ENC22_RS27960	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ENC22_RS27965	COG1166	arginine decarboxylase activity
ENC22_RS27970	COG0366	Alpha amylase catalytic
ENC22_RS27975	COG0783	Belongs to the Dps family
ENC22_RS28005	COG0625	glutathione transferase activity
ENC22_RS28010	COG0625	glutathione transferase activity
ENC22_RS28025	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ENC22_RS28040	COG2918	glutathione biosynthetic process
ENC22_RS28045	COG2183	response to ionizing radiation
ENC22_RS28055	COG0210	DNA helicase
ENC22_RS28060	COG0464	growth
ENC22_RS28140	COG2205	protein histidine kinase activity
ENC22_RS28165	COG2823	Periplasmic or secreted lipoprotein
ENC22_RS28180	COG2885	chlorophyll binding
ENC22_RS28205	COG3237	CsbD-like
ENC22_RS28215	COG3239	Fatty acid desaturase
ENC22_RS28220	COG0330	HflC and HflK could
ENC22_RS28240	COG5001	Diguanylate cyclase
ENC22_RS28240	COG5002	protein histidine kinase activity
ENC22_RS28240	COG3447	MASE1 domain protein
ENC22_RS28270	COG4585	Histidine kinase
ENC22_RS28300	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ENC22_RS28305	COG4181	ATPase activity
ENC22_RS28320	COG0509	glycine decarboxylation via glycine cleavage system
ENC22_RS28330	COG3401	FG-GAP repeat protein
ENC22_RS28335	COG0366	Alpha amylase catalytic
ENC22_RS28350	COG0778	Nitroreductase
ENC22_RS28360	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
ENC22_RS28385	COG1797	cobyrinic acid a,c-diamide synthase activity
ENC22_RS28390	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
ENC22_RS28445	COG1846	Transcriptional regulator
ENC22_RS28445	COG0456	acetyltransferase
ENC22_RS28450	COG0789	Transcriptional regulator
ENC22_RS28460	COG1280	lysine exporter protein (LysE YggA)
ENC22_RS28485	COG1278	Cold shock
ENC22_RS28560	COG0456	acetyltransferase
ENC22_RS28650	COG2003	Belongs to the UPF0758 family
ENC22_RS28685	COG0123	including yeast histone deacetylase and acetoin utilization protein
ENC22_RS28710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ENC22_RS28715	COG4771	TonB-dependent receptor
ENC22_RS28725	COG1169	isochorismate synthase
ENC22_RS28730	COG1021	2,3-dihydroxybenzoate-AMP ligase
ENC22_RS28740	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ENC22_RS28745	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ENC22_RS28750	COG0402	S-adenosylhomocysteine deaminase activity
ENC22_RS28760	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ENC22_RS28765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ENC22_RS28770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ENC22_RS28775	COG1120	ATPase activity
ENC22_RS28780	COG1028	Short-chain dehydrogenase reductase Sdr
ENC22_RS28815	COG1331	Highly conserved protein containing a thioredoxin domain
ENC22_RS28845	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ENC22_RS28860	COG2207	Transcriptional regulator
ENC22_RS28870	COG3789	protein conserved in bacteria
ENC22_RS28875	COG1842	Phage shock protein A
ENC22_RS28890	COG3766	membrane
ENC22_RS28895	COG5463	Belongs to the UPF0441 family
ENC22_RS28900	COG0754	glutathionylspermidine amidase activity
ENC22_RS28910	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ENC22_RS28915	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ENC22_RS28920	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ENC22_RS28980	COG0642	Histidine kinase
ENC22_RS28990	COG0583	DNA-binding transcription factor activity
ENC22_RS28995	COG1595	DNA-templated transcription, initiation
ENC22_RS29015	COG0583	DNA-binding transcription factor activity
ENC22_RS29025	COG1252	NADH dehydrogenase
ENC22_RS29040	COG0625	glutathione transferase activity
ENC22_RS29045	COG1028	Short-chain dehydrogenase reductase Sdr
ENC22_RS29060	COG1028	Short-chain dehydrogenase reductase Sdr
ENC22_RS29085	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ENC22_RS29090	COG0602	queuosine metabolic process
ENC22_RS29100	COG0243	molybdopterin cofactor binding
ENC22_RS29110	COG0596	Alpha beta hydrolase
ENC22_RS29115	COG0252	asparaginase activity
ENC22_RS29150	COG0861	Integral membrane protein TerC family
ENC22_RS29165	COG2205	protein histidine kinase activity
ENC22_RS29175	COG2204	response regulator
ENC22_RS29185	COG2133	pyrroloquinoline quinone binding
ENC22_RS29200	COG0697	spore germination
ENC22_RS29205	COG1846	Transcriptional regulator
ENC22_RS29240	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ENC22_RS29270	COG3710	Transcriptional regulator
ENC22_RS29285	COG2827	Endonuclease containing a URI domain
ENC22_RS29350	COG0784	Response regulator, receiver
ENC22_RS29350	COG2205	protein histidine kinase activity
ENC22_RS29360	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ENC22_RS29375	COG0511	ligase activity, forming carbon-carbon bonds
ENC22_RS29375	COG5016	pyruvate
ENC22_RS29380	COG0439	Biotin carboxylase
ENC22_RS29385	COG1116	anion transmembrane transporter activity
ENC22_RS29395	COG1116	anion transmembrane transporter activity
ENC22_RS29395	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ENC22_RS29415	COG0840	transmembrane signaling receptor activity
ENC22_RS29445	COG2378	regulation of single-species biofilm formation
ENC22_RS29480	COG1733	regulation of RNA biosynthetic process
ENC22_RS29485	COG0789	Transcriptional regulator
ENC22_RS29490	COG2217	Heavy metal translocating P-type atpase
ENC22_RS29530	COG2814	Major facilitator Superfamily
ENC22_RS29535	COG0583	DNA-binding transcription factor activity
ENC22_RS29595	COG2314	TM2 domain
ENC22_RS29600	COG0405	Gamma-glutamyltransferase
ENC22_RS29615	COG1846	Transcriptional regulator
ENC22_RS29625	COG3046	protein related to deoxyribodipyrimidine photolyase
ENC22_RS29650	COG0583	DNA-binding transcription factor activity
ENC22_RS29675	COG2130	NADP-dependent
ENC22_RS29680	COG1028	Short-chain dehydrogenase reductase Sdr
ENC22_RS29690	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ENC22_RS29725	COG1472	Belongs to the glycosyl hydrolase 3 family
ENC22_RS29730	COG1609	Transcriptional regulator
ENC22_RS29740	COG1120	ATPase activity
ENC22_RS29760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ENC22_RS29775	COG0557	exoribonuclease II activity
ENC22_RS29825	COG3978	acetolactate synthase activity
ENC22_RS29840	COG2815	serine threonine protein kinase
ENC22_RS29840	COG0515	serine threonine protein kinase
ENC22_RS29845	COG0631	protein serine/threonine phosphatase activity
ENC22_RS29915	COG0501	Belongs to the peptidase M48B family
ENC22_RS29920	COG1739	Uncharacterized protein family UPF0029
ENC22_RS29925	COG1028	Short-chain dehydrogenase reductase Sdr
ENC22_RS29940	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ENC22_RS29970	COG3738	Protein conserved in bacteria
ENC22_RS29980	COG4608	Belongs to the ABC transporter superfamily
ENC22_RS29985	COG0444	Belongs to the ABC transporter superfamily
ENC22_RS29990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ENC22_RS29995	COG0601	transmembrane transport
ENC22_RS30005	COG1609	Transcriptional regulator
ENC22_RS30015	COG2723	6-phospho-beta-galactosidase activity
ENC22_RS30020	COG0395	ABC-type sugar transport system, permease component
ENC22_RS30025	COG1175	transmembrane transport
ENC22_RS30030	COG1653	transport
ENC22_RS30035	COG1609	Transcriptional regulator
ENC22_RS30055	COG0745	RESPONSE REGULATOR receiver
ENC22_RS30060	COG2205	protein histidine kinase activity
ENC22_RS30065	COG1574	metal-dependent hydrolase with the TIM-barrel fold
ENC22_RS30085	COG2207	Transcriptional regulator
ENC22_RS30090	COG1028	Short-chain dehydrogenase reductase Sdr
ENC22_RS30105	COG3039	Transposase
ENC22_RS30115	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ENC22_RS30115	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ENC22_RS30140	COG2315	Protein conserved in bacteria
ENC22_RS30150	COG1247	-acetyltransferase
ENC22_RS30165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ENC22_RS30220	COG2067	long-chain fatty acid transport protein
ENC22_RS30240	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ENC22_RS30255	COG0159	tryptophan synthase activity
ENC22_RS30260	COG1671	Belongs to the UPF0178 family
ENC22_RS30265	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ENC22_RS30270	COG1349	DNA-binding transcription factor activity
ENC22_RS30275	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ENC22_RS30280	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ENC22_RS30285	COG3284	Transcriptional regulator
ENC22_RS30290	COG3842	ATPase activity
ENC22_RS30295	COG3842	ATPase activity
ENC22_RS30305	COG0395	ABC-type sugar transport system, permease component
ENC22_RS30325	COG0811	peptide transport
ENC22_RS30330	COG0848	biopolymer transport protein
ENC22_RS30340	COG2188	Transcriptional regulator
ENC22_RS30345	COG3842	ATPase activity
ENC22_RS30350	COG0395	ABC-type sugar transport system, permease component
ENC22_RS30365	COG0363	glucosamine-6-phosphate deaminase activity
ENC22_RS30370	COG2971	BadF BadG BcrA BcrD
ENC22_RS30375	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ENC22_RS30380	COG2066	Belongs to the glutaminase family
ENC22_RS30395	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ENC22_RS30405	COG1056	cytidyltransferase-related domain
ENC22_RS30405	COG1051	belongs to the nudix hydrolase family
ENC22_RS30425	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
ENC22_RS30435	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ENC22_RS30440	COG1397	ADP-ribosylglycohydrolase
ENC22_RS30460	COG1132	(ABC) transporter
ENC22_RS30465	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ENC22_RS30480	COG0006	proline dipeptidase activity
ENC22_RS30485	COG2020	methyltransferase activity
ENC22_RS30525	COG2373	Large extracellular alpha-helical protein
ENC22_RS30530	COG4953	penicillin-binding protein 1C
ENC22_RS30730	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ENC22_RS30735	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ENC22_RS30740	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ENC22_RS30745	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ENC22_RS30750	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ENC22_RS30755	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ENC22_RS30760	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ENC22_RS30765	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ENC22_RS30775	COG0356	it plays a direct role in the translocation of protons across the membrane
ENC22_RS30785	COG1475	DNA binding
ENC22_RS30790	COG1192	Involved in chromosome partitioning
ENC22_RS30795	COG0357	Ribosomal RNA small subunit methyltransferase G
ENC22_RS30800	COG0445	tRNA wobble uridine modification
ENC22_RS30810	COG2076	Multidrug Resistance protein
ENC22_RS30815	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ENC22_RS30820	COG0706	membrane insertase activity
ENC22_RS30825	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ENC22_RS30830	COG0594	ribonuclease P activity
ENC22_RS30835	COG0230	Belongs to the bacterial ribosomal protein bL34 family