locus-tag	class	description
EY643_RS00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
EY643_RS00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
EY643_RS00015	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
EY643_RS00020	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
EY643_RS00040	ENOG4105CGY	Dna recombination protein
EY643_RS00045	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
EY643_RS00050	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
EY643_RS00055	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
EY643_RS00065	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
EY643_RS00070	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
EY643_RS00075	ENOG4105C1A	potassium transporter peripheral membrane
EY643_RS00080	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
EY643_RS00085	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
EY643_RS00090	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
EY643_RS00100	ENOG4105C79	DNA protecting protein DprA
EY643_RS00110	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
EY643_RS00115	ENOG4105E2X	shikimate dehydrogenase
EY643_RS00120	ENOG4108Z0R	Transferase
EY643_RS00135	ENOG4107R73	Mate efflux family protein
EY643_RS00150	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
EY643_RS00155	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
EY643_RS00175	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
EY643_RS00185	ENOG4105C2M	dna polymerase I
EY643_RS00195	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
EY643_RS00200	ENOG4105MPD	Cytochrome
EY643_RS00205	ENOG4106RE7	Cytochrome
EY643_RS00210	ENOG4108Z33	Thiol disulfide Interchange Protein
EY643_RS00215	ENOG4105C6T	cysteine synthase
EY643_RS00220	ENOG4105C2C	drug resistance transporter, Bcr CflA
EY643_RS00225	ENOG4106517	Short-chain dehydrogenase reductase Sdr
EY643_RS00230	ENOG4105EW9	transcriptional regulator AsnC family
EY643_RS00235	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
EY643_RS00245	ENOG4105C7B	Threonine dehydratase
EY643_RS00255	ENOG4105C01	Dihydroxy-acid dehydratase
EY643_RS00270	ENOG4107QZM	n-acetylglutamate synthase
EY643_RS00280	ENOG4105CJ3	phosphate transporter
EY643_RS00285	ENOG4107IX6	phosphate transport regulator
EY643_RS00290	ENOG4107QHF	type ii secretion system protein e
EY643_RS00295	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
EY643_RS00300	ENOG4105XA0	heptosyltransferase ii
EY643_RS00305	ENOG4105D16	lipopolysaccharide heptosyltransferase i
EY643_RS00310	ENOG4107RJ7	Glycosyl transferase (Group 1
EY643_RS00315	ENOG4107543	(lipo)polysaccharide
EY643_RS00345	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
EY643_RS00350	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
EY643_RS00355	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
EY643_RS00360	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
EY643_RS00365	ENOG4107QVI	Methyltransferase, type 11
EY643_RS00380	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
EY643_RS00390	ENOG41087SS	fad dependent oxidoreductase
EY643_RS00395	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
EY643_RS00400	ENOG4105DFG	type I secretion outer membrane protein
EY643_RS00410	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
EY643_RS00415	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
EY643_RS00425	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
EY643_RS00430	ENOG4105CAU	Arsenical resistance protein, ArsH
EY643_RS00435	ENOG4105D6J	arsenicaL-resistance protein
EY643_RS00445	ENOG41082YX	Transcriptional regulator, arsr family
EY643_RS00455	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
EY643_RS00460	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
EY643_RS00475	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
EY643_RS00480	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
EY643_RS00505	ENOG4108JQ1	Dehydrogenase
EY643_RS00515	ENOG4105E27	serine threonine protein kinase
EY643_RS00520	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
EY643_RS00525	ENOG4105E0C	molybdate abc transporter
EY643_RS00535	ENOG4105MJ2	Competence protein
EY643_RS00540	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
EY643_RS00545	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
EY643_RS00550	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
EY643_RS00555	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
EY643_RS00560	ENOG4105CSU	acyl-Coa dehydrogenase
EY643_RS00590	ENOG4108IQE	Amp-dependent synthetase and ligase
EY643_RS00595	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
EY643_RS00600	ENOG4105CJP	fad dependent oxidoreductase
EY643_RS00615	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
EY643_RS00625	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
EY643_RS00630	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
EY643_RS00660	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
EY643_RS00675	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
EY643_RS00680	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
EY643_RS00730	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
EY643_RS00755	ENOG4108IFG	nitrite reductase, (NAD(P)H)
EY643_RS00760	ENOG4105D7T	ABC transporter
EY643_RS00770	ENOG4105D7T	ABC transporter
EY643_RS00790	ENOG4105D05	Receptor
EY643_RS00800	ENOG4105BZU	Histidine kinase
EY643_RS00810	ENOG4107R3J	Transporter
EY643_RS00815	ENOG4107QZF	nitrite reductase NADPH large subunit
EY643_RS00820	ENOG4105WZK	nitrite reductase NADPH small subunit
EY643_RS00830	ENOG4105DSF	transport protein
EY643_RS00840	ENOG4105CFC	Transporter
EY643_RS00870	ENOG4105D05	Receptor
EY643_RS00875	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
EY643_RS00890	ENOG41076QQ	Glycosyl transferase, family 2
EY643_RS00920	ENOG4105EY8	ABC transporter
EY643_RS00960	ENOG4105CDV	Ompa motb domain protein
EY643_RS00990	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
EY643_RS01000	ENOG4105CVK	Glutamate decarboxylase
EY643_RS01015	ENOG4105BZU	Histidine kinase
EY643_RS01020	ENOG4105CHR	reductase
EY643_RS01060	ENOG4108IJ0	Aspartate ammonia-lyase
EY643_RS01065	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
EY643_RS01105	ENOG4108KR4	dihydrodipicolinate reductase
EY643_RS01110	ENOG4107ZSV	Receptor
EY643_RS01140	ENOG4105CGD	Nad-dependent epimerase dehydratase
EY643_RS01150	ENOG4105ENH	Sulfatase
EY643_RS01170	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
EY643_RS01185	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
EY643_RS01200	ENOG4107SQI	penicillin amidase
EY643_RS01225	ENOG4107U7N	hydantoinase B oxoprolinase
EY643_RS01230	ENOG4108ESX	Receptor
EY643_RS01245	ENOG4105EUF	amidase EC 3.5.1.4
EY643_RS01250	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
EY643_RS01275	ENOG4108S0J	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'- phosphates (By similarity)
EY643_RS01280	ENOG4105ENH	Sulfatase
EY643_RS01285	ENOG4105CT4	transporter
EY643_RS01310	ENOG4105VRT	cytoplasmic protein
EY643_RS01370	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
EY643_RS01405	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
EY643_RS01430	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
EY643_RS01435	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
EY643_RS01460	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
EY643_RS01520	ENOG4105CNM	Receptor
EY643_RS01615	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
EY643_RS01620	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
EY643_RS01625	ENOG4105KTH	gatB Yqey
EY643_RS01630	ENOG4105VCC	30S ribosomal protein S21
EY643_RS01635	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
EY643_RS01640	ENOG4107ZVW	dihydroneopterin aldolase
EY643_RS01650	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
EY643_RS01655	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
EY643_RS01660	ENOG4105NWN	ApaG protein
EY643_RS01665	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
EY643_RS01690	ENOG4105D3Q	Sugar transferase
EY643_RS01705	ENOG4108I69	Glycosyl transferases group 1
EY643_RS01710	ENOG4105E12	capsule polysaccharide
EY643_RS01765	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
EY643_RS01770	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
EY643_RS01775	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
EY643_RS01780	ENOG4105EHM	Aminoglycoside phosphotransferase
EY643_RS01785	ENOG4108S0S	Nucleotidyl transferase
EY643_RS01790	ENOG4105DJV	ribulose-phosphate 3-epimerase
EY643_RS01795	ENOG4105CRQ	synthase (Component I)
EY643_RS01800	ENOG4105DDQ	anthranilate synthase
EY643_RS01805	ENOG4107QYG	anthranilate phosphoribosyltransferase
EY643_RS01810	ENOG4105DK0	Indole-3-glycerol phosphate synthase
EY643_RS01815	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
EY643_RS01820	ENOG4108UKZ	OsmC family
EY643_RS01830	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
EY643_RS01835	ENOG4105C12	Phosphoribosylglycinamide synthetase
EY643_RS01840	ENOG4105DC1	bifunctional purine biosynthesis protein purh
EY643_RS01850	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
EY643_RS01855	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
EY643_RS01860	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
EY643_RS01865	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
EY643_RS01870	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
EY643_RS01875	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
EY643_RS01895	ENOG4105CQ2	DNA polymerase
EY643_RS01905	ENOG4105BZ4	penicillin-binding protein
EY643_RS01915	ENOG4105DKW	ABC transporter
EY643_RS01930	ENOG4105D52	delta-aminolevulinic acid dehydratase
EY643_RS01935	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
EY643_RS01950	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
EY643_RS01965	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
EY643_RS01980	ENOG4105DR5	peptidase
EY643_RS02020	ENOG4105D78	K07001 NTE family protein
EY643_RS02030	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
EY643_RS02040	ENOG4108IGT	Dipeptidase
EY643_RS02050	ENOG4108URH	decarboxylase
EY643_RS02055	ENOG4105BZM	domain protein
EY643_RS02075	ENOG4105CK2	sodium dicarboxylate symporter
EY643_RS02080	ENOG4105C5X	domain protein
EY643_RS02090	ENOG4105CI2	imidazolone-5-propionate hydrolase
EY643_RS02095	ENOG4105ERG	peptidase m48, ste24p
EY643_RS02135	ENOG4105E6M	Sulphatase-modifying factor protein
EY643_RS02190	ENOG4108DQR	cina-like protein
EY643_RS02205	ENOG4108V1T	peptidylprolyl cis-trans isomerase
EY643_RS02210	ENOG4105D1F	ATP-binding protein
EY643_RS02215	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
EY643_RS02240	ENOG4105C5S	asparaginyl-tRNA synthetase
EY643_RS02250	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
EY643_RS02255	ENOG4108IAB	Phoh family
EY643_RS02265	ENOG4105DJ4	phosphatidylserine decarboxylase
EY643_RS02270	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
EY643_RS02280	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
EY643_RS02285	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
EY643_RS02290	ENOG4105K8N	protein family UPF0079, ATPase
EY643_RS02295	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
EY643_RS02300	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
EY643_RS02305	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
EY643_RS02310	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
EY643_RS02315	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
EY643_RS02320	ENOG4107QJR	hflk protein
EY643_RS02325	ENOG4105EPW	hflc protein
EY643_RS02335	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
EY643_RS02405	ENOG4105CAQ	asparagine synthetase
EY643_RS02420	ENOG4105BZ1	(ABC) transporter
EY643_RS02475	ENOG4105DAY	polysaccharide export protein
EY643_RS02490	ENOG4105PSV	Polysaccharide Biosynthesis Protein
EY643_RS02510	ENOG4105CG5	Glycosyl transferase (Group 1
EY643_RS02515	ENOG4105CK5	oxidoreductase
EY643_RS02530	ENOG4107RRD	Dehydrogenase
EY643_RS02555	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
EY643_RS02560	ENOG4107QQG	Dehydrogenase
EY643_RS02570	ENOG4105DAY	polysaccharide export protein
EY643_RS02575	ENOG4108QV3	biosynthesis protein
EY643_RS02580	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
EY643_RS02595	ENOG4105ESV	Glycosyl transferase, family 4
EY643_RS02620	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
EY643_RS02630	ENOG4105C30	Nad-dependent epimerase dehydratase
EY643_RS02640	ENOG4105CMR	udp-glucose 4-epimerase
EY643_RS02665	ENOG4105D0M	Protease HtpX homolog
EY643_RS02670	ENOG4108V0P	LemA family
EY643_RS02680	ENOG4108UQS	dipeptidase
EY643_RS02710	ENOG4107R37	Glutamate dehydrogenase
EY643_RS02715	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
EY643_RS02720	ENOG4105C2N	RNA methyltransferase TrmH family group 3
EY643_RS02725	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
EY643_RS02740	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
EY643_RS02750	ENOG4105CDU	Replicative dna helicase
EY643_RS02770	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
EY643_RS02785	ENOG4105C5H	ABC transporter
EY643_RS02795	ENOG4105NPQ	Pfam:DUF403
EY643_RS02815	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
EY643_RS02820	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
EY643_RS02825	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
EY643_RS02835	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
EY643_RS02840	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
EY643_RS02845	ENOG4107YIM	Involved in the transcription termination process (By similarity)
EY643_RS02850	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
EY643_RS02855	ENOG4108ZAI	phosphatidylglycerophosphatase a
EY643_RS02865	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
EY643_RS02875	ENOG4108877	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
EY643_RS02900	ENOG4105K64	Glycosyl transferase, family 2
EY643_RS02935	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
EY643_RS02940	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
EY643_RS02945	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
EY643_RS02960	ENOG4105VEJ	Heat shock protein
EY643_RS02965	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
EY643_RS02970	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
EY643_RS02980	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
EY643_RS02985	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
EY643_RS03000	ENOG4108VWS	Yaeq family
EY643_RS03005	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
EY643_RS03015	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
EY643_RS03025	ENOG4107QX3	carboxylase
EY643_RS03030	ENOG4105C1G	acyl-Coa dehydrogenase
EY643_RS03035	ENOG4108Z6Z	Transcriptional regulator
EY643_RS03040	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
EY643_RS03045	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
EY643_RS03050	ENOG4105EXC	Acyl-transferase
EY643_RS03100	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
EY643_RS03110	ENOG4105PM1	preprotein translocase subunit SecE
EY643_RS03115	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
EY643_RS03120	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
EY643_RS03125	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
EY643_RS03130	ENOG4108VZM	50s ribosomal protein L10
EY643_RS03135	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
EY643_RS03140	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
EY643_RS03145	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
EY643_RS03165	ENOG4107E2E	PKHD-type hydroxylase
EY643_RS03170	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
EY643_RS03175	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
EY643_RS03180	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
EY643_RS03185	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
EY643_RS03190	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
EY643_RS03210	ENOG4108V06	Glutathione peroxidase
EY643_RS03225	ENOG4105M0Y	
EY643_RS03230	ENOG4107NA1	Endonuclease Exonuclease phosphatase
EY643_RS03235	ENOG4105CFQ	glutamine synthetase
EY643_RS03245	ENOG4105EQD	regulatoR
EY643_RS03250	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
EY643_RS03255	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
EY643_RS03270	ENOG4105C9M	aspartyl-trna synthetase
EY643_RS03275	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
EY643_RS03280	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
EY643_RS03285	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
EY643_RS03290	ENOG4107YD3	Thioesterase
EY643_RS03295	ENOG4105E02	MotA TolQ exbB proton channel
EY643_RS03300	ENOG4105M8F	Biopolymer transport protein exbD tolR
EY643_RS03310	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
EY643_RS03315	ENOG4105KCK	Peptidoglycan-associated lipoprotein
EY643_RS03320	ENOG4105UFD	tol-pal system protein YbgF
EY643_RS03325	ENOG4107VRB	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
EY643_RS03330	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
EY643_RS03385	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
EY643_RS03395	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EY643_RS03405	ENOG41076HS	cation diffusion facilitator family transporter
EY643_RS03415	ENOG4107ZSV	Receptor
EY643_RS03435	ENOG4105DVW	rieske (2Fe-2S)
EY643_RS03440	ENOG4105C0A	alcohol dehydrogenase
EY643_RS03460	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
EY643_RS03465	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
EY643_RS03470	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
EY643_RS03475	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
EY643_RS03490	ENOG4105CE1	Ferrous iron transport protein b
EY643_RS03515	ENOG4105HBR	Rna-binding protein
EY643_RS03525	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
EY643_RS03530	ENOG4105EEI	dihydropteroate synthase
EY643_RS03535	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
EY643_RS03540	ENOG4105CP7	Triose-phosphate isomerase
EY643_RS03545	ENOG4105NTZ	Preprotein translocase subunit SecG
EY643_RS03555	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
EY643_RS03565	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
EY643_RS03570	ENOG4105CHV	Transcription elongation factor NusA
EY643_RS03575	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
EY643_RS03580	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
EY643_RS03585	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
EY643_RS03590	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
EY643_RS03595	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
EY643_RS03600	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
EY643_RS03605	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
EY643_RS03610	ENOG4105C3G	gtp-binding protein
EY643_RS03615	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
EY643_RS03620	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
EY643_RS03625	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
EY643_RS03635	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
EY643_RS03640	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
EY643_RS03645	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
EY643_RS03655	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
EY643_RS03660	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
EY643_RS03665	ENOG4105D06	uba thif-type nad fad binding protein
EY643_RS03670	ENOG4107QI1	Mate efflux family protein
EY643_RS03695	ENOG4108DG9	Smr protein MutS2
EY643_RS03700	ENOG4105CSM	endonuclease III
EY643_RS03715	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
EY643_RS03720	ENOG4105CE9	30S ribosomal protein S2
EY643_RS03725	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
EY643_RS03735	ENOG4107GFK	fumarate
EY643_RS03740	ENOG4105CJB	Exodeoxyribonuclease I
EY643_RS03745	ENOG4105CXT	aspartate transcarbamylase
EY643_RS03750	ENOG41087AY	ADP-Ribose pyrophosphatase
EY643_RS03755	ENOG4105CJR	Integral membrane protein (MviN
EY643_RS03760	ENOG4105DTN	riboflavin biosynthesis protein ribF
EY643_RS03765	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
EY643_RS03770	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
EY643_RS03775	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
EY643_RS03780	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
EY643_RS03810	ENOG4106855	Competence protein
EY643_RS03820	ENOG4105C4K	Nad synthetase
EY643_RS03825	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EY643_RS03830	ENOG4105C34	Pseudouridine synthase
EY643_RS03835	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
EY643_RS03840	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
EY643_RS03850	ENOG4105C7K	acetolactate synthase
EY643_RS03855	ENOG4108ZP8	Acetolactate synthase small subunit
EY643_RS03865	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
EY643_RS03870	ENOG4105EMY	transcriptional regulator
EY643_RS03875	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
EY643_RS03890	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
EY643_RS03945	ENOG4105DHT	Metal Dependent Phosphohydrolase
EY643_RS03965	ENOG4105VDT	-acetyltransferase
EY643_RS03975	ENOG4105DZB	Electron transport complex
EY643_RS03980	ENOG4108UQQ	Electron transport complex
EY643_RS03985	ENOG4105D6A	Electron transport complex
EY643_RS03995	ENOG4108R3D	Electron transport complex
EY643_RS04000	ENOG4105DGN	Electron transport complex
EY643_RS04005	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
EY643_RS04015	ENOG4105DHP	deoxycytidine triphosphate deaminase
EY643_RS04025	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
EY643_RS04030	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
EY643_RS04040	ENOG4105C02	permease
EY643_RS04045	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
EY643_RS04050	ENOG4105CDV	Ompa motb domain protein
EY643_RS04060	ENOG4105CZ7	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
EY643_RS04065	ENOG4105CHM	Aminotransferase
EY643_RS04070	ENOG4108XM1	transcriptional regulator AsnC family
EY643_RS04115	ENOG4105EMU	Dehydrogenase
EY643_RS04125	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
EY643_RS04135	ENOG4105DGW	oligopeptidase A
EY643_RS04145	ENOG4105C1J	atp-dependent rna helicase
EY643_RS04160	ENOG4106N0C	Provides the rickettsial cell with host ATP in exchange for rickettsial ADP. This is an obligate exchange system. This energy acquiring activity is an important component of rickettsial parasitism
EY643_RS04165	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
EY643_RS04170	ENOG4105C6T	cysteine synthase
EY643_RS04185	ENOG4107S2Z	UPF0761 membrane protein
EY643_RS04190	ENOG4105K89	arsenate reductase
EY643_RS04195	ENOG4105CS1	NAD(P)H quinone oxidoreductase
EY643_RS04205	ENOG4105D07	Signal peptide peptidase, SppA
EY643_RS04215	ENOG4105BZS	acriflavin resistance protein
EY643_RS04220	ENOG4105J12	Multidrug resistance protein mdtN
EY643_RS04260	ENOG4107ZSV	Receptor
EY643_RS04265	ENOG4108QIU	Dehydrogenase
EY643_RS04275	ENOG4105DY2	Paraquat-inducible protein b
EY643_RS04280	ENOG4105DHJ	ABC, transporter
EY643_RS04295	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
EY643_RS04300	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
EY643_RS04305	ENOG4105Q2H	domain protein
EY643_RS04325	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
EY643_RS04330	ENOG4105CHR	reductase
EY643_RS04335	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
EY643_RS04340	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
EY643_RS04345	ENOG4105KUZ	arsenate reductase
EY643_RS04365	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
EY643_RS04370	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
EY643_RS04380	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
EY643_RS04385	ENOG4105VQ7	Rod shape-determining protein MreD
EY643_RS04390	ENOG4108Z03	MAF-like protein
EY643_RS04395	ENOG4105C03	ribonuclease
EY643_RS04405	ENOG4105N42	UPF0307 protein
EY643_RS04410	ENOG4105CJW	magnesium transporter
EY643_RS04415	ENOG41080Z8	PHOSPHOCARRIER protein
EY643_RS04420	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
EY643_RS04425	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
EY643_RS04430	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
EY643_RS04435	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
EY643_RS04440	ENOG4108IUZ	ABC transporter
EY643_RS04460	ENOG4105C2X	Arabinose 5-phosphate isomerase
EY643_RS04475	ENOG4105VFK	BolA family
EY643_RS04480	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
EY643_RS04485	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
EY643_RS04490	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
EY643_RS04500	ENOG4107QNR	UPF0135 protein
EY643_RS04510	ENOG4105D6Z	AFG1 family ATPase
EY643_RS04515	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
EY643_RS04520	ENOG4108UJD	30S ribosomal protein S9
EY643_RS04525	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
EY643_RS04530	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
EY643_RS04535	ENOG4107MKT	Stringent starvation protein a
EY643_RS04540	ENOG4105KB2	stringent starvation protein b
EY643_RS04545	ENOG4105W4M	Transport-associated protein
EY643_RS04555	ENOG41082RQ	UPF0102 protein
EY643_RS04565	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
EY643_RS04575	ENOG4108V6E	Cell division protein mraZ
EY643_RS04580	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
EY643_RS04590	ENOG4105CJN	penicillin-binding protein
EY643_RS04595	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
EY643_RS04600	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
EY643_RS04605	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
EY643_RS04610	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
EY643_RS04615	ENOG4105CNI	cell division protein FtsW
EY643_RS04620	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
EY643_RS04625	ENOG4105DFU	Cell wall formation (By similarity)
EY643_RS04630	ENOG4105CPF	Cell wall formation (By similarity)
EY643_RS04635	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
EY643_RS04640	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
EY643_RS04645	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
EY643_RS04650	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
EY643_RS04655	ENOG4105DR5	peptidase
EY643_RS04660	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
EY643_RS04665	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
EY643_RS04670	ENOG4105M6F	mutator MutT protein
EY643_RS04675	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
EY643_RS04680	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
EY643_RS04690	ENOG4107QHF	type ii secretion system protein e
EY643_RS04710	ENOG4105CKK	Glycosyl transferase, family 2
EY643_RS04725	ENOG4105CSU	acyl-Coa dehydrogenase
EY643_RS04730	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
EY643_RS04735	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
EY643_RS04740	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
EY643_RS04755	ENOG4108PBA	serine threonine protein kinase
EY643_RS04765	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
EY643_RS04775	ENOG41077A9	carbonic anhydrase
EY643_RS04780	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
EY643_RS04800	ENOG4107QHF	type ii secretion system protein e
EY643_RS04805	ENOG4105D7Q	type ii secretion system
EY643_RS04810	ENOG4108VAU	general secretion pathway protein G
EY643_RS04820	ENOG4105X5Z	General secretion pathway protein I
EY643_RS04825	ENOG4108WWZ	General secretion pathway protein J
EY643_RS04850	ENOG4105VCQ	rubredoxin
EY643_RS04855	ENOG4105DC7	peptidase M24
EY643_RS04860	ENOG4105C8J	)-transporter
EY643_RS04865	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
EY643_RS04870	ENOG4105M2Z	protein tyrosine serine phosphatase
EY643_RS04875	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
EY643_RS04885	ENOG4108UNF	response regulator
EY643_RS04890	ENOG4105CBS	Chea signal transduction histidine kinase
EY643_RS04915	ENOG4105BZU	Histidine kinase
EY643_RS04920	ENOG4105X1P	Steroid delta-isomerase
EY643_RS04925	ENOG4105C1G	acyl-Coa dehydrogenase
EY643_RS04930	ENOG4105D2B	acyl-CoA dehydrogenase
EY643_RS04935	ENOG4105C0H	protease
EY643_RS04950	ENOG4105D0M	Protease HtpX homolog
EY643_RS04990	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
EY643_RS05000	ENOG4105CPP	Dehydrogenase, E1 component
EY643_RS05005	ENOG4107R0V	Pyruvate dehydrogenase
EY643_RS05015	ENOG4105E39	Enoyl-CoA hydratase
EY643_RS05025	ENOG4105KHC	sulfurtransferase
EY643_RS05035	ENOG4105CRK	lysyL-tRNA synthetase
EY643_RS05045	ENOG4105BZU	Histidine kinase
EY643_RS05050	ENOG4108UXN	response regulator
EY643_RS05055	ENOG4105F8J	Adenylate Guanylate cyclase
EY643_RS05060	ENOG4105IJJ	transcriptional regulator, crp fnr family
EY643_RS05065	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
EY643_RS05070	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
EY643_RS05075	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
EY643_RS05085	ENOG4108Z6B	deaminase
EY643_RS05100	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
EY643_RS05105	ENOG4108ETH	Formylglycinamide ribotide synthetase
EY643_RS05110	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
EY643_RS05115	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
EY643_RS05120	ENOG4105ECY	inositol monophosphatase
EY643_RS05130	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
EY643_RS05135	ENOG4105C3J	Cysteine desulfurase
EY643_RS05140	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
EY643_RS05145	ENOG4108Z4V	iron-sulfur cluster assembly
EY643_RS05150	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
EY643_RS05155	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
EY643_RS05160	ENOG4108ZIT	Ferredoxin, 2FE-2S
EY643_RS05165	ENOG4105WVQ	Fe-S assembly protein IscX
EY643_RS05170	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
EY643_RS05175	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
EY643_RS05190	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
EY643_RS05200	ENOG4105N21	Membrane
EY643_RS05205	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
EY643_RS05210	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
EY643_RS05215	ENOG4105VIG	Sec-independent protein translocase protein TatC
EY643_RS05240	ENOG4105CIG	ABC transporter
EY643_RS05250	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
EY643_RS05280	ENOG4105PDP	Short chain dehydrogenase
EY643_RS05285	ENOG4108ZX5	transcriptional regulator
EY643_RS05295	ENOG4105EGS	Mechanosensitive ion channel
EY643_RS05300	ENOG4105D7N	magnesium and cobalt transport protein CorA
EY643_RS05310	ENOG4105E3B	Multicopper oxidase
EY643_RS05315	ENOG4107RET	Isocitrate lyase
EY643_RS05320	ENOG4105EFI	regulatoR
EY643_RS05325	ENOG4105BZU	Histidine kinase
EY643_RS05335	ENOG4105C26	Dehydrogenase
EY643_RS05420	ENOG4105FUY	alpha subunit
EY643_RS05425	ENOG4105CC9	acyl-Coa dehydrogenase
EY643_RS05435	ENOG4105CPQ	Dehydrogenase
EY643_RS05475	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
EY643_RS05485	ENOG4105C1G	acyl-Coa dehydrogenase
EY643_RS05490	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
EY643_RS05525	ENOG4105FUY	alpha subunit
EY643_RS05535	ENOG4108KEZ	Dehydrogenase
EY643_RS05610	ENOG4105EMU	Dehydrogenase
EY643_RS05635	ENOG41063TF	transcriptional regulator (AraC
EY643_RS05640	ENOG4108EKI	Dehydrogenase
EY643_RS05645	ENOG4105C1G	acyl-Coa dehydrogenase
EY643_RS05650	ENOG4105E39	Enoyl-CoA hydratase
EY643_RS05655	ENOG4108IPT	Naphthoate synthase
EY643_RS05660	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
EY643_RS05665	ENOG4105EBM	Alpha Beta Hydrolase Fold protein
EY643_RS05680	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
EY643_RS05690	ENOG4107YCY	Transcriptional regulator
EY643_RS05705	ENOG4107YCY	Transcriptional regulator
EY643_RS05720	ENOG4105DPW	Major facilitator superfamily MFS_1
EY643_RS05725	ENOG4105CHR	reductase
EY643_RS05730	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
EY643_RS05735	ENOG4105EY3	heparinase II III family protein
EY643_RS05770	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
EY643_RS05775	ENOG4105CHR	reductase
EY643_RS05785	ENOG4108V0E	nucleoside 2-deoxyribosyltransferase YtoQ
EY643_RS05790	ENOG4105C1G	acyl-Coa dehydrogenase
EY643_RS05795	ENOG4105CEY	Amp-dependent synthetase and ligase
EY643_RS05810	ENOG4105XRQ	Xanthine dehydrogenase accessory factor
EY643_RS05840	ENOG4107ZSV	Receptor
EY643_RS05850	ENOG4108HH4	Major Facilitator Superfamily
EY643_RS05855	ENOG4105IIU	Aminopeptidase
EY643_RS05890	ENOG4105EIK	Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane (By similarity)
EY643_RS05910	ENOG4108YZN	class I peptide chain release factor
EY643_RS05915	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
EY643_RS05920	ENOG4105C9U	ATP-dependent DNA helicase RecQ
EY643_RS05945	ENOG4107QN1	sodium solute
EY643_RS05955	ENOG41080XP	Cbs domain
EY643_RS05965	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
EY643_RS05990	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
EY643_RS05995	ENOG4105U3E	Transcriptional regulator
EY643_RS06025	ENOG4107RDJ	Sulfotransferase
EY643_RS06035	ENOG4105CSU	acyl-Coa dehydrogenase
EY643_RS06040	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
EY643_RS06045	ENOG4105CPI	Metal Dependent Phosphohydrolase
EY643_RS06050	ENOG4108SXK	Transporter Drug Metabolite Exporter family
EY643_RS06055	ENOG4105ERG	peptidase m48, ste24p
EY643_RS06070	ENOG4105G6Z	alkaline phosphatase
EY643_RS06075	ENOG4108YZA	Nitrogen regulatory protein pii
EY643_RS06080	ENOG4105BZU	Histidine kinase
EY643_RS06095	ENOG4105D74	hydrolase
EY643_RS06100	ENOG4105C9X	ppx gppa phosphatase
EY643_RS06105	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
EY643_RS06120	ENOG4107R7A	Allophanate hydrolase subunit 2
EY643_RS06130	ENOG4105E7W	lamb ycsf family protein
EY643_RS06135	ENOG4105CFM	UPF0317 protein
EY643_RS06140	ENOG4105C29	acyl-CoA thioesterase
EY643_RS06150	ENOG4105BZS	acriflavin resistance protein
EY643_RS06175	ENOG4105IPI	Membrane
EY643_RS06185	ENOG4105Y49	secretion protein, HlyD family
EY643_RS06210	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
EY643_RS06215	ENOG4105CHU	acetyl-coa acetyltransferase
EY643_RS06230	ENOG4105EV9	Alpha Beta Hydrolase
EY643_RS06235	ENOG4105CHU	acetyl-coa acetyltransferase
EY643_RS06240	ENOG4106YT9	Enoyl-CoA hydratase
EY643_RS06250	ENOG4105GPY	SprT protein
EY643_RS06265	ENOG4105BZU	Histidine kinase
EY643_RS06270	ENOG4105C1G	acyl-Coa dehydrogenase
EY643_RS06280	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
EY643_RS06285	ENOG4108UKI	Enoyl-CoA hydratase
EY643_RS06315	ENOG4107RN6	Monooxygenase
EY643_RS06340	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
EY643_RS06345	ENOG4105F8V	Hydrolase, tatD family
EY643_RS06360	ENOG4107QR9	Iron-sulfur cluster binding protein
EY643_RS06375	ENOG4105DUX	Transporter
EY643_RS06400	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
EY643_RS06410	ENOG4107QSA	Oxaloacetate decarboxylase
EY643_RS06415	ENOG4105D9Q	decarboxylase (Beta subunit)
EY643_RS06440	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
EY643_RS06450	ENOG4105K9H	YciI-like protein
EY643_RS06455	ENOG4107835	probably involved in intracellular septation (By similarity)
EY643_RS06460	ENOG4105DB7	PHP domain protein
EY643_RS06465	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
EY643_RS06475	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
EY643_RS06480	ENOG4105FE9	pseudouridine synthase
EY643_RS06485	ENOG4105UBK	short-chain dehydrogenase reductase
EY643_RS06490	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
EY643_RS06495	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
EY643_RS06500	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
EY643_RS06505	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
EY643_RS06510	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
EY643_RS06525	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
EY643_RS06530	ENOG4105CAT	Cytidine monophosphate kinase
EY643_RS06535	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
EY643_RS06540	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
EY643_RS06550	ENOG4105CFV	Tetratricopeptide repeat protein
EY643_RS06555	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
EY643_RS06560	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
EY643_RS06565	ENOG4105ECP	epimerase
EY643_RS06570	ENOG4105ESV	Glycosyl transferase, family 4
EY643_RS06585	ENOG4105C0A	alcohol dehydrogenase
EY643_RS06595	ENOG4108R4U	Hnh endonuclease
EY643_RS06605	ENOG4105VMP	Transcriptional regulator
EY643_RS06625	ENOG4108C33	Resolvase
EY643_RS06650	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
EY643_RS06660	ENOG4105ENH	Sulfatase
EY643_RS06665	ENOG4105IFJ	Histidine kinase
EY643_RS06670	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
EY643_RS06675	ENOG4105CP2	von willebrand factor, type a
EY643_RS06685	ENOG4105D8T	Acyltransferase
EY643_RS06695	ENOG4105C22	threonyL-tRNA synthetase
EY643_RS06700	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
EY643_RS06705	ENOG41082NX	50s ribosomal protein l35
EY643_RS06710	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
EY643_RS06715	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
EY643_RS06720	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
EY643_RS06725	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
EY643_RS06730	ENOG4105WJX	transcriptional regulator MERR family
EY643_RS06755	ENOG4105EA8	2-Nitropropane dioxygenase
EY643_RS06775	ENOG4105D2B	acyl-CoA dehydrogenase
EY643_RS06780	ENOG4105C1G	acyl-Coa dehydrogenase
EY643_RS06785	ENOG4105CHU	acetyl-coa acetyltransferase
EY643_RS06795	ENOG4105CRW	Short chain fatty acid transporter
EY643_RS06800	ENOG4105C1G	acyl-Coa dehydrogenase
EY643_RS06805	ENOG4105C0A	alcohol dehydrogenase
EY643_RS06810	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
EY643_RS06815	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
EY643_RS06840	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
EY643_RS06880	ENOG4105EUB	pirin domain protein
EY643_RS06900	ENOG4105E2Q	3-(3-hydroxy-phenyl)propionate hydroxylase
EY643_RS06920	ENOG4105WJZ	Glutathione S-transferase, C-terminal domain
EY643_RS06940	ENOG4105E39	Enoyl-CoA hydratase
EY643_RS06965	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
EY643_RS06980	ENOG4105E39	Enoyl-CoA hydratase
EY643_RS06985	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
EY643_RS06990	ENOG4105D2B	acyl-CoA dehydrogenase
EY643_RS07025	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
EY643_RS07065	ENOG4105CHR	reductase
EY643_RS07070	ENOG4105BZU	Histidine kinase
EY643_RS07075	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
EY643_RS07080	ENOG4105EW9	transcriptional regulator AsnC family
EY643_RS07085	ENOG4105C26	Dehydrogenase
EY643_RS07095	ENOG4105EJC	lysr family transcriptional regulator
EY643_RS07100	ENOG4108JA1	polyketide synthase
EY643_RS07105	ENOG4108M8W	Monooxygenase
EY643_RS07110	ENOG4105E1F	short-chain dehydrogenase reductase
EY643_RS07145	ENOG4108478	ec 3.2.1.18
EY643_RS07150	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
EY643_RS07160	ENOG4105CHR	reductase
EY643_RS07170	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
EY643_RS07175	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
EY643_RS07185	ENOG4107W7X	Aldolase
EY643_RS07195	ENOG4108ZX5	transcriptional regulator
EY643_RS07205	ENOG4105D44	asparaginase
EY643_RS07220	ENOG4105EMN	RNA polymerase sigma factor
EY643_RS07225	ENOG4105J8Z	peptidase S8 and S53, subtilisin, kexin, sedolisin
EY643_RS07245	ENOG4105DY8	decarboxylase
EY643_RS07260	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
EY643_RS07265	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
EY643_RS07275	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
EY643_RS07305	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
EY643_RS07320	ENOG4105CQ7	ATP-dependent helicase
EY643_RS07330	ENOG4105E18	UPF0276 protein
EY643_RS07340	ENOG410903C	(LipO)protein
EY643_RS07355	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
EY643_RS07370	ENOG4105C8V	SAICAR synthetase
EY643_RS07380	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
EY643_RS07415	ENOG41085AF	Cytochrome
EY643_RS07420	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
EY643_RS07425	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
EY643_RS07445	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
EY643_RS07450	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
EY643_RS07455	ENOG4105EGD	dinuclear metal center protein, YbgI family
EY643_RS07460	ENOG4105P8F	nudix hydrolase
EY643_RS07465	ENOG4108Z0R	Transferase
EY643_RS07475	ENOG4108JU6	CBS domain protein
EY643_RS07480	ENOG4106KVJ	cytochrome C assembly protein
EY643_RS07485	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EY643_RS07490	ENOG4105K5M	30s ribosomal protein S16
EY643_RS07495	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
EY643_RS07500	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
EY643_RS07505	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
EY643_RS07510	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
EY643_RS07515	ENOG4105T95	Thiol disulfide interChange protein
EY643_RS07520	ENOG4105CHM	Aminotransferase
EY643_RS07525	ENOG4105D6E	homoserine dehydrogenase
EY643_RS07530	ENOG4105D98	threonine synthase
EY643_RS07535	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
EY643_RS07545	ENOG4108Z6Z	Transcriptional regulator
EY643_RS07555	ENOG4105D3G	Pseudouridine synthase
EY643_RS07560	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
EY643_RS07565	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
EY643_RS07570	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
EY643_RS07575	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
EY643_RS07580	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
EY643_RS07585	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
EY643_RS07590	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
EY643_RS07600	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
EY643_RS07605	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
EY643_RS07610	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
EY643_RS07620	ENOG4108K5P	(LipO)protein
EY643_RS07625	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
EY643_RS07640	ENOG4105CK7	Sodium proline symporter
EY643_RS07660	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
EY643_RS07680	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
EY643_RS07690	ENOG4105DNH	Major Facilitator
EY643_RS07700	ENOG4105DCY	Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide (By similarity)
EY643_RS07725	ENOG4105DE9	3-keto-5-aminohexanoate cleavage enzyme
EY643_RS07740	ENOG4108IGT	Dipeptidase
EY643_RS07760	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
EY643_RS07765	ENOG4105C26	Dehydrogenase
EY643_RS07775	ENOG4105CQB	FAD linked oxidase domain protein
EY643_RS07785	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
EY643_RS07790	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
EY643_RS07800	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
EY643_RS07835	ENOG4105DYW	oxidoreductase
EY643_RS07840	ENOG4105CSU	acyl-Coa dehydrogenase
EY643_RS07870	ENOG4105CY0	Metallo-Beta-Lactamase
EY643_RS07880	ENOG4105MIR	Phenylalanine 4-monooxygenase
EY643_RS07885	ENOG4108RXX	maleylacetoacetate isomerase
EY643_RS07895	ENOG4105I9P	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)
EY643_RS07905	ENOG4105F7P	transcriptional regulator AsnC family
EY643_RS07935	ENOG4107RJ1	sodium solute
EY643_RS07955	ENOG4108J2P	Alpha beta hydrolase fold
EY643_RS07960	ENOG4105CGU	Enoyl-CoA hydratase
EY643_RS07975	ENOG4107QX3	carboxylase
EY643_RS07980	ENOG4105C1G	acyl-Coa dehydrogenase
EY643_RS07990	ENOG4105C1G	acyl-Coa dehydrogenase
EY643_RS08030	ENOG4105DNH	Major Facilitator
EY643_RS08045	ENOG4105C5F	glutamine synthetase
EY643_RS08050	ENOG4105C0A	alcohol dehydrogenase
EY643_RS08055	ENOG4105C09	Bile acid
EY643_RS08075	ENOG4105EUZ	Beta-lactamase domain protein
EY643_RS08095	ENOG4105E39	Enoyl-CoA hydratase
EY643_RS08105	ENOG4105EMU	Dehydrogenase
EY643_RS08120	ENOG4105CC0	LysR family Transcriptional regulator
EY643_RS08125	ENOG4107QPD	alcohol dehydrogenase
EY643_RS08135	ENOG4105GKE	subunit e
EY643_RS08145	ENOG4108IEG	Formate dehydrogenase Alpha subunit
EY643_RS08150	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
EY643_RS08160	ENOG4105MPN	Membrane
EY643_RS08175	ENOG4107RNH	Outer membrane receptor FepA
EY643_RS08200	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
EY643_RS08210	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
EY643_RS08215	ENOG4108YZT	Adenosylcobinamide kinase
EY643_RS08220	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
EY643_RS08225	ENOG4105EHG	Permease protein
EY643_RS08230	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
EY643_RS08235	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
EY643_RS08240	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
EY643_RS08245	ENOG4105CVJ	phosphoglycerate mutase
EY643_RS08250	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
EY643_RS08255	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
EY643_RS08280	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
EY643_RS08285	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
EY643_RS08310	ENOG4105BZU	Histidine kinase
EY643_RS08315	ENOG4108VAU	general secretion pathway protein G
EY643_RS08335	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
EY643_RS08345	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
EY643_RS08355	ENOG4105DUM	transcriptional regulator, lysR family
EY643_RS08360	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
EY643_RS08365	ENOG4107RIQ	Sulfate adenylate transferase
EY643_RS08375	ENOG4105BZU	Histidine kinase
EY643_RS08380	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
EY643_RS08400	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
EY643_RS08425	ENOG4105CHR	reductase
EY643_RS08440	ENOG4105D25	secreted protein
EY643_RS08480	ENOG4109015	Biopolymer transport protein exbD tolR
EY643_RS08495	ENOG4105CI2	imidazolone-5-propionate hydrolase
EY643_RS08510	ENOG4105CHR	reductase
EY643_RS08520	ENOG410900P	UPF0336 protein
EY643_RS08560	ENOG4105F2C	Acetyl-CoA acetyltransferase
EY643_RS08595	ENOG4105X7H	acyl-CoA dehydrogenase
EY643_RS08600	ENOG4107Z3H	Transcriptional regulator, TetR family
EY643_RS08605	ENOG4108RK3	acyl-Coa dehydrogenase
EY643_RS08630	ENOG4108IG5	Transcriptional regulator
EY643_RS08640	ENOG4108Z86	Glutamine amidotransferase
EY643_RS08650	ENOG4105E2B	Taurine dioxygenase
EY643_RS08655	ENOG4105E0F	Histidine kinase
EY643_RS08660	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
EY643_RS08675	ENOG4105D05	Receptor
EY643_RS08695	ENOG4105CZE	histidine utilization repressor
EY643_RS08710	ENOG4108UAU	isochorismatase
EY643_RS08715	ENOG4108M3R	transcriptional activator CadC
EY643_RS08725	ENOG4105HDK	L-asparaginase
EY643_RS08730	ENOG4105DR9	pseudouridine synthase
EY643_RS08745	ENOG4107MKT	Stringent starvation protein a
EY643_RS08750	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
EY643_RS08760	ENOG4105EJQ	L-serine dehydratase
EY643_RS08765	ENOG4105EN6	Membrane
EY643_RS08770	ENOG4105K5B	UPF0225 protein
EY643_RS08775	ENOG4105C5H	ABC transporter
EY643_RS08785	ENOG4105C1J	atp-dependent rna helicase
EY643_RS08790	ENOG4108YZY	peptidylprolyl cis-trans isomerase
EY643_RS08820	ENOG4105CH2	amidohydrolase
EY643_RS08840	ENOG4105D05	Receptor
EY643_RS08850	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
EY643_RS08855	ENOG4105E39	Enoyl-CoA hydratase
EY643_RS08860	ENOG4105D2B	acyl-CoA dehydrogenase
EY643_RS08870	ENOG4105DS1	cytochrome b561
EY643_RS08875	ENOG4105C6X	Major Facilitator
EY643_RS08930	ENOG4105CT4	transporter
EY643_RS08935	ENOG4105E39	Enoyl-CoA hydratase
EY643_RS08945	ENOG4105CHR	reductase
EY643_RS08950	ENOG4108UKI	Enoyl-CoA hydratase
EY643_RS08955	ENOG4105CHR	reductase
EY643_RS08960	ENOG4105E2A	Dehydrogenase
EY643_RS08975	ENOG4105JXH	GntR family transcriptional regulator
EY643_RS08980	ENOG4105CT3	Monooxygenase
EY643_RS08995	ENOG4108IQE	Amp-dependent synthetase and ligase
EY643_RS09000	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
EY643_RS09025	ENOG4105CHR	reductase
EY643_RS09040	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
EY643_RS09075	ENOG4105W2Z	cytochrome C, class I
EY643_RS09090	ENOG4105CM2	brancheD-chain amino acid aminotransferase
EY643_RS09105	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
EY643_RS09135	ENOG4108RMJ	sensory transduction regulator
EY643_RS09140	ENOG4106PMH	Extracellular solute-binding protein family 3
EY643_RS09150	ENOG4105H37	Glyoxalase Bleomycin resistance protein (Dioxygenase
EY643_RS09180	ENOG4105E39	Enoyl-CoA hydratase
EY643_RS09185	ENOG4108TKH	Nitroreductase
EY643_RS09190	ENOG4105E39	Enoyl-CoA hydratase
EY643_RS09205	ENOG4107SQI	penicillin amidase
EY643_RS09210	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
EY643_RS09215	ENOG4105CHU	acetyl-coa acetyltransferase
EY643_RS09220	ENOG4105ECQ	AraC Family Transcriptional Regulator
EY643_RS09225	ENOG4107RX2	synthase
EY643_RS09230	ENOG4105HDD	phospholipase
EY643_RS09245	ENOG4105E51	psp operon transcriptional activator
EY643_RS09255	ENOG41087YS	Phage shock protein A
EY643_RS09265	ENOG4105FM1	phage shock protein C
EY643_RS09270	ENOG4108ZX5	transcriptional regulator
EY643_RS09280	ENOG4105Q9Y	Universal stress protein
EY643_RS09290	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
EY643_RS09295	ENOG4105CFP	Peptidase U32
EY643_RS09300	ENOG4105CKW	Inner membrane protein yedI
EY643_RS09315	ENOG4105D7A	ATP-binding protein
EY643_RS09320	ENOG4105CGZ	zinc metallopeptidase
EY643_RS09365	ENOG4105UQX	Mate efflux family protein
EY643_RS09400	ENOG4105CQ7	ATP-dependent helicase
EY643_RS09405	ENOG4105BZS	acriflavin resistance protein
EY643_RS09410	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
EY643_RS09415	ENOG4105CCT	upf0313 protein
EY643_RS09420	ENOG4107ZSV	Receptor
EY643_RS09425	ENOG4105EYW	Ion transport protein
EY643_RS09430	ENOG4105JAB	phenazine biosynthesis protein, phzf family
EY643_RS09440	ENOG4108UJV	acyl-CoA thioesterase i
EY643_RS09445	ENOG4108I0Y	(ABC) transporter
EY643_RS09450	ENOG4105CV6	ABC transporter, permease
EY643_RS09460	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
EY643_RS09465	ENOG4108UHJ	MAF-like protein
EY643_RS09475	ENOG4105VGS	50s ribosomal protein l32
EY643_RS09480	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
EY643_RS09485	ENOG4105CHR	reductase
EY643_RS09490	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
EY643_RS09495	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
EY643_RS09505	ENOG4105HHA	aminodeoxychorismate lyase
EY643_RS09510	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
EY643_RS09515	ENOG4107QRG	dna polymerase iii
EY643_RS09535	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
EY643_RS09540	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
EY643_RS09545	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
EY643_RS09550	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
EY643_RS09555	ENOG4105K70	DNA-binding protein
EY643_RS09560	ENOG4105EIN	peptidylprolyl cis-trans isomerase
EY643_RS09575	ENOG4105CN1	protease
EY643_RS09600	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
EY643_RS09605	ENOG4105X1P	Steroid delta-isomerase
EY643_RS09650	ENOG4108HNZ	carboxyl transferase
EY643_RS09660	ENOG4105I08	Pseudouridine synthase
EY643_RS09665	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
EY643_RS09670	ENOG4105BZ1	(ABC) transporter
EY643_RS09675	ENOG4105BZ1	(ABC) transporter
EY643_RS09680	ENOG4105D65	subunit l
EY643_RS09690	ENOG4108JPZ	Monovalent cation H antiporter subunit D
EY643_RS09695	ENOG4108JPZ	Monovalent cation H antiporter subunit D
EY643_RS09700	ENOG4105MKQ	Monovalent cation H antiporter subunit C
EY643_RS09710	ENOG4105KJM	monovalent cation h antiporter subunit g
EY643_RS09720	ENOG4105SC1	monovalent cation H antiporter subunit E
EY643_RS09805	ENOG4105DZR	Type I site-specific deoxyribonuclease
EY643_RS09855	ENOG4107TTA	Xylose isomerase domain protein TIM barrel
EY643_RS09870	ENOG4105CIB	oxidoreductase Domain protein
EY643_RS09885	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
EY643_RS09895	ENOG4105DEI	Mannitol dehydrogenase
EY643_RS09900	ENOG4105D2H	Uronic isomerase
EY643_RS09905	ENOG4107YCY	Transcriptional regulator
EY643_RS09920	ENOG4105D9R	oxidoreductase
EY643_RS09925	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
EY643_RS09930	ENOG4105FQ6	thiopurine methyltransferase
EY643_RS09940	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
EY643_RS09950	ENOG4105D9P	serine threonine protein kinase
EY643_RS09955	ENOG4105E39	Enoyl-CoA hydratase
EY643_RS09960	ENOG4105C1G	acyl-Coa dehydrogenase
EY643_RS09965	ENOG4105CHR	reductase
EY643_RS09980	ENOG4105D9P	serine threonine protein kinase
EY643_RS09995	ENOG4105ERU	peptidase
EY643_RS10005	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
EY643_RS10010	ENOG4107RZZ	dna polymerase iii epsilon subunit
EY643_RS10015	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
EY643_RS10020	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
EY643_RS10025	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
EY643_RS10030	ENOG4105E9H	Lytic Murein transglycosylase
EY643_RS10035	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
EY643_RS10050	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
EY643_RS10060	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
EY643_RS10065	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
EY643_RS10070	ENOG4105C3R	Methionine synthase
EY643_RS10080	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
EY643_RS10090	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
EY643_RS10095	ENOG4105C10	Electron transfer flavoprotein
EY643_RS10100	ENOG4105BZJ	Electron transfer flavoprotein
EY643_RS10105	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
EY643_RS10110	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
EY643_RS10115	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
EY643_RS10120	ENOG4105WMR	Protein CrcB homolog
EY643_RS10125	ENOG4105D1H	recombination factor protein RarA
EY643_RS10130	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
EY643_RS10135	ENOG4105CNU	cell division protein FtsK
EY643_RS10140	ENOG4105C3M	thioredoxin reductase
EY643_RS10145	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
EY643_RS10150	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
EY643_RS10155	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
EY643_RS10160	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
EY643_RS10165	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
EY643_RS10170	ENOG4108R99	pseudouridine synthase
EY643_RS10180	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
EY643_RS10185	ENOG41075W9	High frequency lysogenization protein HflD homolog
EY643_RS10190	ENOG4107QTF	adenylosuccinate lyase
EY643_RS10195	ENOG4105EZE	Cupin 4 family protein
EY643_RS10205	ENOG4105E9K	Isocitrate dehydrogenase
EY643_RS10210	ENOG4105KNA	-acetyltransferase
EY643_RS10220	ENOG4105BZU	Histidine kinase
EY643_RS10225	ENOG4105DJT	lAO AO transport system ATPase
EY643_RS10240	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
EY643_RS10250	ENOG4105CRQ	synthase (Component I)
EY643_RS10255	ENOG4105ECA	phosphoserine phosphatase homoserine phosphotransferase bifunctional protein
EY643_RS10260	ENOG4107R11	Transcriptional regulator
EY643_RS10270	ENOG4105CYC	Transferase
EY643_RS10275	ENOG4105BZG	amino acid carrier protein
EY643_RS10280	ENOG4105K6H	D-cysteine desulfhydrase
EY643_RS10285	ENOG4105VIE	preprotein translocase, subunit YajC
EY643_RS10290	ENOG4105CGK	Exodeoxyribonuclease III
EY643_RS10305	ENOG4105K59	histidine triad (HIT) protein
EY643_RS10310	ENOG4106A3M	Cytochrome p-450
EY643_RS10320	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EY643_RS10335	ENOG4108ZAF	Molybdopterin
EY643_RS10340	ENOG4105M00	molybdopterin converting factor, subunit 1
EY643_RS10345	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
EY643_RS10350	ENOG4105DYW	oxidoreductase
EY643_RS10365	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
EY643_RS10370	ENOG4105E3A	(ABC) transporter
EY643_RS10375	ENOG4105DA5	(ABC) transporter
EY643_RS10390	ENOG4108RXX	maleylacetoacetate isomerase
EY643_RS10405	ENOG4105E0X	reductase
EY643_RS10415	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
EY643_RS10420	ENOG4105C2M	dna polymerase I
EY643_RS10425	ENOG4108BPE	-transporting atpase
EY643_RS10450	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
EY643_RS10455	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
EY643_RS10460	ENOG4105EUJ	GTP cyclohydrolase i
EY643_RS10480	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
EY643_RS10485	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
EY643_RS10490	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
EY643_RS10495	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
EY643_RS10500	ENOG4107QN2	dihydrolipoyl dehydrogenase
EY643_RS10505	ENOG4105C7S	Dehydrogenase
EY643_RS10510	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
EY643_RS10515	ENOG4105E33	succinate dehydrogenase
EY643_RS10520	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
EY643_RS10530	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
EY643_RS10535	ENOG4105BZN	citrate synthase
EY643_RS10545	ENOG4105CIH	Imidazole acetol-phosphate transaminase
EY643_RS10560	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
EY643_RS10565	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
EY643_RS10575	ENOG4105C8U	phosphate abc transporter
EY643_RS10590	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
EY643_RS10595	ENOG4105BZU	Histidine kinase
EY643_RS10600	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
EY643_RS10610	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
EY643_RS10615	ENOG4105BZ8	glutamate synthase
EY643_RS10625	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
EY643_RS10630	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
EY643_RS10635	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
EY643_RS10640	ENOG4108W0S	formate-dependent nitrite reductase complex
EY643_RS10645	ENOG4105KWW	Biogenesis protein
EY643_RS10650	ENOG4107QX9	Thiol disulfide interChange protein
EY643_RS10655	ENOG4105DA4	cytochrome c-type biogenesis protein
EY643_RS10660	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
EY643_RS10670	ENOG41060IM	Heme exporter protein
EY643_RS10675	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
EY643_RS10680	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
EY643_RS10685	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
EY643_RS10725	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
EY643_RS10730	ENOG4105EI2	Pseudouridine synthase
EY643_RS10735	ENOG4105C03	ribonuclease
EY643_RS10745	ENOG4106TNF	Periplasmic binding protein
EY643_RS10760	ENOG4105DEN	Luciferase family
EY643_RS10770	ENOG4108MN8	Membrane
EY643_RS10775	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
EY643_RS10795	ENOG4107QYG	anthranilate phosphoribosyltransferase
EY643_RS10800	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
EY643_RS10825	ENOG4105C8J	)-transporter
EY643_RS10855	ENOG4105ECP	epimerase
EY643_RS10860	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
EY643_RS10890	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
EY643_RS10895	ENOG4105D4A	Cell wall formation (By similarity)
EY643_RS10900	ENOG4105KJF	protein tyrosine phosphatase
EY643_RS10905	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
EY643_RS10915	ENOG4105BZ1	(ABC) transporter
EY643_RS10920	ENOG4109015	Biopolymer transport protein exbD tolR
EY643_RS10930	ENOG4108EC8	DNA internalization-related competence protein ComEC
EY643_RS10940	ENOG4105D60	lipoprotein releasing system transmembrane protein
EY643_RS10945	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
EY643_RS10960	ENOG4105CJ2	(LipO)protein
EY643_RS10965	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
EY643_RS10970	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
EY643_RS10980	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
EY643_RS10985	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
EY643_RS10990	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
EY643_RS11000	ENOG4108JA2	transcriptioN-repair coupling factor
EY643_RS11010	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
EY643_RS11015	ENOG4105D64	Mechanosensitive ion channel
EY643_RS11025	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
EY643_RS11040	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
EY643_RS11050	ENOG41081QV	Universal stress protein
EY643_RS11065	ENOG4108UQN	AraC family transcriptional regulator
EY643_RS11080	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
EY643_RS11090	ENOG4108ZZ3	UPF0260 protein
EY643_RS11095	ENOG4105VNG	YcgL domain-containing protein
EY643_RS11105	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
EY643_RS11110	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
EY643_RS11115	ENOG4107QMP	dna polymerase iii subunits gamma and tau
EY643_RS11130	ENOG4108IJF	Heavy metal efflux pump, CzcA
EY643_RS11140	ENOG4105EFZ	amidohydrolase
EY643_RS11160	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
EY643_RS11165	ENOG4105C8N	cysteinyl-tRNA synthetase
EY643_RS11170	ENOG4105CX6	glutaminyL-tRNA synthetase
EY643_RS11180	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
EY643_RS11185	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
EY643_RS11195	ENOG4107QIJ	Aconitate hydratase 2
EY643_RS11200	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
EY643_RS11215	ENOG4105EG6	Saccharopine dehydrogenase
EY643_RS11230	ENOG4105F8C	transglutaminase domain-containing protein
EY643_RS11240	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
EY643_RS11245	ENOG4105C28	cystathionine
EY643_RS11250	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
EY643_RS11255	ENOG4105E96	Colicin v production protein
EY643_RS11265	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
EY643_RS11270	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
EY643_RS11275	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
EY643_RS11285	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
EY643_RS11300	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
EY643_RS11305	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
EY643_RS11310	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
EY643_RS11315	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
EY643_RS11320	ENOG4108MP6	LysR family Transcriptional regulator
EY643_RS11335	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
EY643_RS11340	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
EY643_RS11370	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
EY643_RS11390	ENOG4108ZG0	Ompa motb domain protein
EY643_RS11400	ENOG4105CFU	surface antigen
EY643_RS11405	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
EY643_RS11440	ENOG4105CIR	epoxide hydrolase
EY643_RS11450	ENOG4105D2B	acyl-CoA dehydrogenase
EY643_RS11455	ENOG4105CC9	acyl-Coa dehydrogenase
EY643_RS11460	ENOG41069P5	Protein slyX homolog
EY643_RS11465	ENOG4108ZJT	translation initiation factor, Sui1
EY643_RS11490	ENOG4107SC1	transglycosylase
EY643_RS11495	ENOG4108SBK	dioxygenase, subunit beta
EY643_RS11500	ENOG4105FUY	alpha subunit
EY643_RS11580	ENOG4105CNM	Receptor
EY643_RS11600	ENOG4105VEQ	Cold shock protein
EY643_RS11615	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
EY643_RS11625	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
EY643_RS11635	ENOG4105BZU	Histidine kinase
EY643_RS11685	ENOG4105BZU	Histidine kinase
EY643_RS11705	ENOG4105C09	Bile acid
EY643_RS11730	ENOG4108UCS	ABC, transporter
EY643_RS11735	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
EY643_RS11755	ENOG4107U2T	alpha beta
EY643_RS11810	ENOG4105CHF	Glutathione S-transferase
EY643_RS11815	ENOG4105CWB	LysR family transcriptional Regulator
EY643_RS11825	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
EY643_RS11895	ENOG4105BZU	Histidine kinase
EY643_RS11905	ENOG4107MKT	Stringent starvation protein a
EY643_RS11910	ENOG410902C	phosphohistidine phosphatase, SixA
EY643_RS11915	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
EY643_RS11920	ENOG4108IPT	Naphthoate synthase
EY643_RS11945	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
EY643_RS11965	ENOG4107TE5	Lipid kinase
EY643_RS11970	ENOG4105CXK	mandelate racemase muconate lactonizing
EY643_RS11990	ENOG4105JSC	dimethylmenaquinone methyltransferase
EY643_RS11995	ENOG4108IGT	Dipeptidase
EY643_RS12040	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
EY643_RS12045	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
EY643_RS12055	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
EY643_RS12070	ENOG4108YZY	peptidylprolyl cis-trans isomerase
EY643_RS12075	ENOG4105VEQ	Cold shock protein
EY643_RS12085	ENOG4107RZC	phospholipase d
EY643_RS12100	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
EY643_RS12110	ENOG4107RGH	Aldehyde dehydrogenase
EY643_RS12120	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
EY643_RS12135	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
EY643_RS12150	ENOG4105K6V	RNA polymerase
EY643_RS12160	ENOG4107QHF	type ii secretion system protein e
EY643_RS12165	ENOG4105KKX	ATPase associated with various cellular activities aaa_5
EY643_RS12170	ENOG4105EUJ	GTP cyclohydrolase i
EY643_RS12185	ENOG4108UPT	UPF0178 protein
EY643_RS12230	ENOG4105W1Y	Transcriptional regulator
EY643_RS12240	ENOG41082K6	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
EY643_RS12260	ENOG4105PGM	cation diffusion facilitator family transporter
EY643_RS12285	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
EY643_RS12305	ENOG4105C59	p-type ATPase
EY643_RS12335	ENOG4105BZU	Histidine kinase
EY643_RS12340	ENOG4105CQB	FAD linked oxidase domain protein
EY643_RS12345	ENOG4105EU8	FAD linked oxidase domain protein
EY643_RS12350	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
EY643_RS12355	ENOG4108IQE	Amp-dependent synthetase and ligase
EY643_RS12375	ENOG4105WFT	During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity)
EY643_RS12380	ENOG4105C7I	Dehydrogenase
EY643_RS12385	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
EY643_RS12405	ENOG4107QVM	von Willebrand factor, type A
EY643_RS12415	ENOG4105CD8	aminopeptidase N
EY643_RS12425	ENOG4105VUT	cytoplasmic protein
EY643_RS12435	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
EY643_RS12440	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
EY643_RS12460	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
EY643_RS12465	ENOG4108S24	Fumarate reduCtase
EY643_RS12470	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
EY643_RS12475	ENOG4105E33	succinate dehydrogenase
EY643_RS12480	ENOG4108JJ7	ABC transporter
EY643_RS12485	ENOG4108HRK	Histidine kinase
EY643_RS12490	ENOG4108VAC	response regulator
EY643_RS12530	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
EY643_RS12535	ENOG4108Q5F	Tetr family transcriptional regulator
EY643_RS12545	ENOG4107RGH	Aldehyde dehydrogenase
EY643_RS12565	ENOG4105EV9	Alpha Beta Hydrolase
EY643_RS12585	ENOG41069NU	Nitroreductase
EY643_RS12600	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
EY643_RS12610	ENOG4105C1G	acyl-Coa dehydrogenase
EY643_RS12630	ENOG4105EVZ	LysR family transcriptional regulator
EY643_RS12640	ENOG4105CYM	Glutathione S-transferase
EY643_RS12660	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
EY643_RS12670	ENOG4105CT4	transporter
EY643_RS12675	ENOG4105CHR	reductase
EY643_RS12680	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
EY643_RS12705	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
EY643_RS12710	ENOG4108Z4U	Ferredoxin
EY643_RS12725	ENOG4107Z7P	Ferredoxin
EY643_RS12730	ENOG4108ZX5	transcriptional regulator
EY643_RS12735	ENOG4105VPI	YqaE family transport protein
EY643_RS12760	ENOG41064T2	transcriptional regulator, lysR family
EY643_RS12770	ENOG4105XDF	Protein of unknown function (DUF1272)
EY643_RS12785	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
EY643_RS12790	ENOG4105C26	Dehydrogenase
EY643_RS12850	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
EY643_RS12900	ENOG4108UAU	isochorismatase
EY643_RS12905	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
EY643_RS12910	ENOG4105C26	Dehydrogenase
EY643_RS12915	ENOG4105C1G	acyl-Coa dehydrogenase
EY643_RS12965	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
EY643_RS12980	ENOG4108J2P	Alpha beta hydrolase fold
EY643_RS13005	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
EY643_RS13010	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
EY643_RS13025	ENOG4105DFM	M18 family aminopeptidase
EY643_RS13030	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
EY643_RS13035	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
EY643_RS13040	ENOG41072GX	Peptidase M22 Glycoprotease
EY643_RS13045	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
EY643_RS13055	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
EY643_RS13060	ENOG4105DXN	mazG family
EY643_RS13065	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
EY643_RS13070	ENOG4105C6T	cysteine synthase
EY643_RS13075	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
EY643_RS13080	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
EY643_RS13085	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
EY643_RS13095	ENOG4105C3F	Signal peptidase i
EY643_RS13100	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
EY643_RS13105	ENOG4105C0H	protease
EY643_RS13115	ENOG4105VQK	sigma E regulatory protein, MucB RseB
EY643_RS13120	ENOG41069E1	anti sigma-E protein RseA
EY643_RS13125	ENOG4105EMN	RNA polymerase sigma factor
EY643_RS13130	ENOG4108IYU	L-aspartate oxidase
EY643_RS13140	ENOG4105Y75	tpr repeat protein
EY643_RS13165	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
EY643_RS13190	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
EY643_RS13200	ENOG4105BZU	Histidine kinase
EY643_RS13210	ENOG4105D4P	Coproporphyrinogen iii oxidase
EY643_RS13215	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
EY643_RS13225	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
EY643_RS13240	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
EY643_RS13275	ENOG4105EIF	outer membrane protein W
EY643_RS13285	ENOG4105FR1	rard protein
EY643_RS13320	ENOG4108KC1	acyl-Coa dehydrogenase
EY643_RS13325	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
EY643_RS13335	ENOG4105C72	UPF0176 protein
EY643_RS13340	ENOG4105M85	Bola protein
EY643_RS13345	ENOG4105EQD	regulatoR
EY643_RS13360	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
EY643_RS13370	ENOG4108K5H	permease YjgP YjgQ family protein
EY643_RS13375	ENOG4108M8S	permease YjgP YjgQ family protein
EY643_RS13380	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
EY643_RS13385	ENOG4105MYG	DNA polymerase iii, chi subunit
EY643_RS13390	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
EY643_RS13395	ENOG4105VEQ	Cold shock protein
EY643_RS13400	ENOG4105VEQ	Cold shock protein
EY643_RS13450	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
EY643_RS13455	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
EY643_RS13460	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
EY643_RS13465	ENOG4108UHU	Aldolase
EY643_RS13470	ENOG4106KNT	transcriptional regulator
EY643_RS13480	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
EY643_RS13485	ENOG4105X23	Endonuclease Exonuclease phosphatase
EY643_RS13490	ENOG4105J5T	Amp-dependent synthetase and ligase
EY643_RS13495	ENOG4105C1J	atp-dependent rna helicase
EY643_RS13515	ENOG4105DHI	Methyltransferase
EY643_RS13520	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
EY643_RS13535	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
EY643_RS13540	ENOG4107S6Z	Na H antiporter
EY643_RS13545	ENOG4105DG4	malate L-lactate dehydrogenase
EY643_RS13555	ENOG4105GNX	MltA-interacting MipA family protein
EY643_RS13575	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
EY643_RS13585	ENOG4105ED2	Beta-lactamase
EY643_RS13595	ENOG4105CYC	Transferase
EY643_RS13640	ENOG4105CPQ	Dehydrogenase
EY643_RS13645	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
EY643_RS13655	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
EY643_RS13675	ENOG4105CDY	transcriptional regulatory protein
EY643_RS13695	ENOG4107QX3	carboxylase
EY643_RS13710	ENOG4105EGS	Mechanosensitive ion channel
EY643_RS13720	ENOG4105EQD	regulatoR
EY643_RS13730	ENOG4105CHU	acetyl-coa acetyltransferase
EY643_RS13735	ENOG4107QWG	2-Nitropropane dioxygenase
EY643_RS13780	ENOG4105CC9	acyl-Coa dehydrogenase
EY643_RS13785	ENOG4108J2P	Alpha beta hydrolase fold
EY643_RS13805	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
EY643_RS13840	ENOG4105EA8	2-Nitropropane dioxygenase
EY643_RS13860	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
EY643_RS13870	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
EY643_RS13890	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
EY643_RS13895	ENOG4105CFH	Aspartokinase
EY643_RS13900	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
EY643_RS13910	ENOG4105W49	UPF0434 protein
EY643_RS13920	ENOG4108RRZ	Transcription elongation factor GreB
EY643_RS13940	ENOG4108RG0	uracil-dna glycosylase
EY643_RS13945	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EY643_RS14000	ENOG41061MV	Arylsulfatase
EY643_RS14015	ENOG4105C0B	DNA polymerase III (alpha subunit)
EY643_RS14020	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
EY643_RS14030	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
EY643_RS14035	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
EY643_RS14040	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
EY643_RS14045	ENOG4105X4K	outer membrane chaperone skp
EY643_RS14050	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EY643_RS14055	ENOG4105DZP	Membrane-associated zinc metalloprotease
EY643_RS14060	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
EY643_RS14065	ENOG4105KNE	Phosphatidate cytidylyltransferase
EY643_RS14070	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
EY643_RS14075	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
EY643_RS14080	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
EY643_RS14090	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
EY643_RS14100	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
EY643_RS14105	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
EY643_RS14120	ENOG41080UX	Methyltransferase
EY643_RS14130	ENOG4105EYM	Major Facilitator superfamily
EY643_RS14145	ENOG4108RT7	Glycosyl transferase, family 2
EY643_RS14150	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
EY643_RS14165	ENOG4105GVR	general secretion pathway protein D
EY643_RS14205	ENOG4108VAU	general secretion pathway protein G
EY643_RS14210	ENOG4105D7Q	type ii secretion system
EY643_RS14215	ENOG4107QHF	type ii secretion system protein e
EY643_RS14220	ENOG4105CHU	acetyl-coa acetyltransferase
EY643_RS14230	ENOG4105D2B	acyl-CoA dehydrogenase
EY643_RS14245	ENOG4105F2C	Acetyl-CoA acetyltransferase
EY643_RS14250	ENOG4105D2B	acyl-CoA dehydrogenase
EY643_RS14255	ENOG4105CC9	acyl-Coa dehydrogenase
EY643_RS14260	ENOG4105E39	Enoyl-CoA hydratase
EY643_RS14265	ENOG4105EA8	2-Nitropropane dioxygenase
EY643_RS14290	ENOG4105CEY	Amp-dependent synthetase and ligase
EY643_RS14310	ENOG4105C3Q	Glycosyl transferase, family 2
EY643_RS14315	ENOG4108ZFX	Mannosyl-3-phosphoglycerate phosphatase
EY643_RS14325	ENOG4107QSN	dihydrolipoamide acetyltransferase
EY643_RS14330	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
EY643_RS14335	ENOG4107QXK	peptidase
EY643_RS14345	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
EY643_RS14350	ENOG4105ERG	peptidase m48, ste24p
EY643_RS14355	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
EY643_RS14370	ENOG4106YT9	Enoyl-CoA hydratase
EY643_RS14375	ENOG4105BZU	Histidine kinase
EY643_RS14385	ENOG4105BZU	Histidine kinase
EY643_RS14390	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
EY643_RS14400	ENOG4105BZU	Histidine kinase
EY643_RS14415	ENOG4105E39	Enoyl-CoA hydratase
EY643_RS14420	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
EY643_RS14425	ENOG4105UQX	Mate efflux family protein
EY643_RS14440	ENOG4105DYW	oxidoreductase
EY643_RS14445	ENOG4105C1G	acyl-Coa dehydrogenase
EY643_RS14450	ENOG4105X7H	acyl-CoA dehydrogenase
EY643_RS14455	ENOG4107QR8	Thioredoxin
EY643_RS14460	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
EY643_RS14465	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
EY643_RS14470	ENOG4105CFG	Acts as a chaperone (By similarity)
EY643_RS14475	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EY643_RS14480	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
EY643_RS14485	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
EY643_RS14490	ENOG41090R7	Ferric uptake
EY643_RS14495	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
EY643_RS14500	ENOG4105VDB	UPF0125 protein
EY643_RS14505	ENOG4108Z1B	Cyclase dehydrase
EY643_RS14510	ENOG4105C8J	)-transporter
EY643_RS14515	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
EY643_RS14520	ENOG4105HF0	Membrane
EY643_RS14575	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
EY643_RS14580	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
EY643_RS14600	ENOG4105Z6S	cytochrome C, class I
EY643_RS14610	ENOG4108RVA	ribokinase
EY643_RS14615	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
EY643_RS14620	ENOG4105C2J	ABC transporter
EY643_RS14625	ENOG4105CNN	ABC, transporter
EY643_RS14630	ENOG4105CB2	alcohol dehydrogenase
EY643_RS14635	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
EY643_RS14640	ENOG4105C5Q	Transcriptional regulator
EY643_RS14675	ENOG4107T6V	glycerophosphoryl diester phosphodiesterase
EY643_RS14705	ENOG4105C7B	Threonine dehydratase
EY643_RS14720	ENOG4105CKU	formyltetrahydrofolate synthetase
EY643_RS14735	ENOG4105ETE	Transcriptional regulator (LacI family
EY643_RS14740	ENOG4105CE4	GlcNAc 6-P deacetylase
EY643_RS14745	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
EY643_RS14750	ENOG4105RD7	BadF BadG BcrA BcrD
EY643_RS14755	ENOG4105E2D	ec 3.2.1.52
EY643_RS14760	ENOG4105CK7	Sodium proline symporter
EY643_RS14775	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
EY643_RS14785	ENOG410690C	hydroxylamine oxidase
EY643_RS14820	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
EY643_RS14870	ENOG4108RFG	Tetr family transcriptional regulator
EY643_RS14880	ENOG4105CT4	transporter
EY643_RS14900	ENOG4108RU0	short-chain dehydrogenase reductase
EY643_RS14905	ENOG4105CHR	reductase
EY643_RS14935	ENOG4105DJG	MaoC domain protein dehydratase
EY643_RS14990	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
EY643_RS14995	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
EY643_RS15000	ENOG4105CHR	reductase
EY643_RS15010	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
EY643_RS15030	ENOG4105VMP	Transcriptional regulator
EY643_RS15080	ENOG4107RZC	phospholipase d
EY643_RS15095	ENOG4105E6M	Sulphatase-modifying factor protein
EY643_RS15100	ENOG41067HS	methyltransferase
EY643_RS15180	ENOG4105C7N	Xanthine uracil vitamin C permease
EY643_RS15205	ENOG4105WD1	Membrane
EY643_RS15210	ENOG4105CD5	CoA-binding domain protein
EY643_RS15225	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
EY643_RS15230	ENOG4108ZX5	transcriptional regulator
EY643_RS15240	ENOG4105DZG	Dehydrogenase
EY643_RS15270	ENOG4105CDV	Ompa motb domain protein
EY643_RS15280	ENOG4105BZU	Histidine kinase
EY643_RS15295	ENOG4105WH1	Two component transcriptional regulator luxr family
EY643_RS15315	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
EY643_RS15320	ENOG4105DUM	transcriptional regulator, lysR family
EY643_RS15325	ENOG4105D6N	CoA-transferase, subunit a
EY643_RS15330	ENOG4107QNJ	CoA-transferase subunit B
EY643_RS15335	ENOG4105CHU	acetyl-coa acetyltransferase
EY643_RS15340	ENOG4105C5H	ABC transporter
EY643_RS15350	ENOG4105CGF	Aromatic amino acid aminotransferase
EY643_RS15355	ENOG4105CIN	aminoacyl-histidine dipeptidase
EY643_RS15370	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
EY643_RS15375	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
EY643_RS15380	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
EY643_RS15395	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
EY643_RS15410	ENOG4108UYB	regulatoR
EY643_RS15415	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
EY643_RS15420	ENOG41084BA	UPF0250 protein
EY643_RS15425	ENOG4105DZ1	carboxypeptidase
EY643_RS15435	ENOG4105CVE	Lytic murein transglycosylase
EY643_RS15440	ENOG4105CNI	cell division protein FtsW
EY643_RS15445	ENOG4105CJN	penicillin-binding protein
EY643_RS15450	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
EY643_RS15460	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
EY643_RS15465	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
EY643_RS15470	ENOG4105D3R	alkyl hydroperoxide reductase
EY643_RS15480	ENOG4105M2J	Glutaredoxin
EY643_RS15485	ENOG4105C8Y	Acetylornithine aminotransferase
EY643_RS15490	ENOG4105DBV	ornithine carbamoyltransferase
EY643_RS15495	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
EY643_RS15500	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
EY643_RS15530	ENOG4105CHU	acetyl-coa acetyltransferase
EY643_RS15545	ENOG4108RPX	mosc domain containing protein
EY643_RS15550	ENOG4105DVT	helicase
EY643_RS15570	ENOG4105M2Z	protein tyrosine serine phosphatase
EY643_RS15575	ENOG4105MKU	Transcriptional regulator
EY643_RS15580	ENOG41080IJ	Diacylglycerol kinase
EY643_RS15585	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
EY643_RS15595	ENOG4108ZX5	transcriptional regulator
EY643_RS15620	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
EY643_RS15625	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
EY643_RS15640	ENOG41062JF	Transcriptional regulator
EY643_RS15670	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
EY643_RS15705	ENOG4105D9M	gamma-glutamylcysteine synthetase
EY643_RS15715	ENOG4105PBF	Anti-RNA polymerase sigma 70 factor
EY643_RS15720	ENOG4108V1T	peptidylprolyl cis-trans isomerase
EY643_RS15730	ENOG4105K56	Transcriptional regulator
EY643_RS15735	ENOG4105C5H	ABC transporter
EY643_RS15740	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
EY643_RS15755	ENOG4105K63	Thioredoxin
EY643_RS15760	ENOG4105CSR	polyphosphate kinase 2
EY643_RS15765	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
EY643_RS15770	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
EY643_RS15775	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
EY643_RS15780	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
EY643_RS15790	ENOG4105ENH	Sulfatase
EY643_RS15800	ENOG4107RDB	Major Facilitator
EY643_RS15805	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
EY643_RS15810	ENOG4108NEV	two component transcriptional regulator, LytTR family
EY643_RS15825	ENOG4105X0D	Fimbrial protein
EY643_RS15850	ENOG4106855	Competence protein
EY643_RS15860	ENOG4108ZT0	50S ribosomal protein l17
EY643_RS15865	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
EY643_RS15870	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
EY643_RS15875	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
EY643_RS15880	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EY643_RS15885	ENOG41067V7	50S ribosomal protein L36
EY643_RS15890	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
EY643_RS15895	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
EY643_RS15900	ENOG4105VPB	50S ribosomal protein L30
EY643_RS15905	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
EY643_RS15910	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
EY643_RS15915	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
EY643_RS15920	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
EY643_RS15925	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
EY643_RS15930	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EY643_RS15935	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
EY643_RS15940	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
EY643_RS15945	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
EY643_RS15950	ENOG41083MP	50s ribosomal protein l29
EY643_RS15955	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
EY643_RS15960	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
EY643_RS15965	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
EY643_RS15970	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
EY643_RS15975	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EY643_RS15985	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
EY643_RS15990	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
EY643_RS15995	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
EY643_RS16000	ENOG4105SCY	DNAK suppressor
EY643_RS16015	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
EY643_RS16020	ENOG4105XT2	Transcriptional regulator
EY643_RS16030	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
EY643_RS16035	ENOG4105C9A	Phoh family
EY643_RS16040	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
EY643_RS16045	ENOG4108JU5	Magnesium and cobalt efflux protein
EY643_RS16055	ENOG4105C8T	Leucyl-tRNA synthetase
EY643_RS16065	ENOG4105DJF	DNA polymerase III, delta' subunit
EY643_RS16090	ENOG4105Q9Y	Universal stress protein
EY643_RS16095	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
EY643_RS16100	ENOG4108R6G	acetyltransferase
EY643_RS16185	ENOG4105QNF	Outer membrane lipoprotein
EY643_RS16245	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
EY643_RS16250	ENOG4105C0B	DNA polymerase III (alpha subunit)
EY643_RS16255	ENOG4105I9P	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)
EY643_RS16270	ENOG4105CDH	Citrulline--aspartate ligase
EY643_RS16275	ENOG4105EKE	dihydroorotase
EY643_RS16290	ENOG4108MGY	Histidine kinase
EY643_RS16295	ENOG4108ZGA	chew protein
EY643_RS16335	ENOG4105DFU	Cell wall formation (By similarity)
EY643_RS16340	ENOG4105CTQ	phosphohexokinase
EY643_RS16345	ENOG4107YDW	inorganic pyrophosphatase EC 3.6.1.1
EY643_RS16355	ENOG4105PW4	Sugar fermentation stimulation protein homolog
EY643_RS16360	ENOG4105CHM	Aminotransferase
EY643_RS16365	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EY643_RS16370	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
EY643_RS16385	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
EY643_RS16390	ENOG4105DJ0	Poly(A) Polymerase
EY643_RS16395	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EY643_RS16405	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
EY643_RS16410	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
EY643_RS16415	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
EY643_RS16420	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EY643_RS16425	ENOG4105K46	50S ribosomal protein l27
EY643_RS16430	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
EY643_RS16435	ENOG4105EAH	synthase
EY643_RS16440	ENOG4107QP8	phosphohexose isomerase
EY643_RS16450	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
EY643_RS16460	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
EY643_RS16475	ENOG4105ECF	c-methyltransferase
EY643_RS16480	ENOG41076E6	Uroporphyrinogen-III Synthase
EY643_RS16490	ENOG4105CH7	arginosuccinase
EY643_RS16500	ENOG4105XQ6	frataxin-like protein
EY643_RS16510	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
EY643_RS16515	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
EY643_RS16525	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
EY643_RS16530	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
EY643_RS16535	ENOG4108YZA	Nitrogen regulatory protein pii
EY643_RS16550	ENOG4108YZA	Nitrogen regulatory protein pii
EY643_RS16560	ENOG4105W0Z	cytoplasmic protein
EY643_RS16565	ENOG4105C0P	Mg chelatase subunit ChlI
EY643_RS16570	ENOG4106A3M	Cytochrome p-450
EY643_RS16575	ENOG4105CTD	carboxy-peptidase
EY643_RS16580	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
EY643_RS16585	ENOG4105CHU	acetyl-coa acetyltransferase
EY643_RS16595	ENOG4105C4R	Atp-dependent dna helicase
EY643_RS16615	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
EY643_RS16625	ENOG4108K3A	Glutathione S-transferase
EY643_RS16635	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
EY643_RS16670	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
EY643_RS16685	ENOG4107SM8	Adenylate Guanylate cyclase
EY643_RS16715	ENOG4105BZU	Histidine kinase
EY643_RS16725	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
EY643_RS16740	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
EY643_RS16775	ENOG4105D3Q	Sugar transferase
EY643_RS16815	ENOG4108Q5F	Tetr family transcriptional regulator
EY643_RS16845	ENOG4105CHR	reductase
EY643_RS16880	ENOG4108KC1	acyl-Coa dehydrogenase
EY643_RS16930	ENOG4107S73	homocitrate synthase
EY643_RS16945	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
EY643_RS16950	ENOG4107QSN	dihydrolipoamide acetyltransferase
EY643_RS17055	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EY643_RS17070	ENOG4105CJ2	(LipO)protein
EY643_RS17075	ENOG4107QM2	Aldo Keto reductase
EY643_RS17080	ENOG4108R85	Short chain dehydrogenase
EY643_RS17085	ENOG4108J2P	Alpha beta hydrolase fold
EY643_RS17105	ENOG4105HDK	L-asparaginase
EY643_RS17125	ENOG4107RBR	Receptor
EY643_RS17130	ENOG4107RZC	phospholipase d
EY643_RS17135	ENOG4105HMD	
EY643_RS17140	ENOG4107RZC	phospholipase d
EY643_RS17145	ENOG4105CHR	reductase
EY643_RS17160	ENOG4107S6Z	Na H antiporter
EY643_RS17175	ENOG4105JKW	Valine--pyruvate aminotransferase
EY643_RS17215	ENOG4105DQU	oxidoreductase, subunit beta
EY643_RS17220	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
EY643_RS17230	ENOG4105CNG	UPF0061 protein
EY643_RS17235	ENOG4105KWI	UPF0339 protein
EY643_RS17255	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
EY643_RS17265	ENOG4105H3G	oxidoreductase
EY643_RS17280	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
EY643_RS17300	ENOG4105BZG	amino acid carrier protein
EY643_RS17315	ENOG4105CPC	Aldo Keto reductase
EY643_RS17330	ENOG4105ENH	Sulfatase
EY643_RS17350	ENOG4105X7H	acyl-CoA dehydrogenase
EY643_RS17380	ENOG4105XA0	heptosyltransferase ii
EY643_RS17390	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
EY643_RS17400	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
EY643_RS17405	ENOG41061WM	D-Alanyl-D-Alanine
EY643_RS17430	ENOG4105ENH	Sulfatase
EY643_RS17445	ENOG4105ENH	Sulfatase
EY643_RS17455	ENOG4105EFX	secretion protein, HlyD family
EY643_RS17505	ENOG4105E6M	Sulphatase-modifying factor protein
EY643_RS17560	ENOG4105CHU	acetyl-coa acetyltransferase
EY643_RS17570	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
EY643_RS17580	ENOG4105DCF	alanine dehydrogenase
EY643_RS17590	ENOG4105C1G	acyl-Coa dehydrogenase
EY643_RS17595	ENOG4105DND	Transcriptional regulator
EY643_RS17605	ENOG4107RDJ	Sulfotransferase
EY643_RS17615	ENOG4105CFQ	glutamine synthetase
EY643_RS17620	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
EY643_RS17625	ENOG4105E5D	amino acid
EY643_RS17630	ENOG4105D3P	Mannan endo-1,4-beta-mannosidase
EY643_RS17635	ENOG4105DFY	n-acylglucosamine 2-epimerase
EY643_RS17640	ENOG4105HY2	Glycosidase related protein
EY643_RS17645	ENOG4105ETE	Transcriptional regulator (LacI family
EY643_RS17660	ENOG4105ETE	Transcriptional regulator (LacI family
EY643_RS17675	ENOG4105QV4	Tryptophan halogenase
EY643_RS17685	ENOG4105CK7	Sodium proline symporter
EY643_RS17690	ENOG4105E2V	Glycosyltransferase 36
EY643_RS17700	ENOG4105CT4	transporter
EY643_RS17705	ENOG4105E2V	Glycosyltransferase 36
EY643_RS17710	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
EY643_RS17720	ENOG4105D25	secreted protein
EY643_RS17730	ENOG4105DUM	transcriptional regulator, lysR family
EY643_RS17735	ENOG4105DP0	ferredoxin-NADP reductase
EY643_RS17765	ENOG4108UQY	Iron-storage protein
EY643_RS17770	ENOG4105HMD	
EY643_RS17815	ENOG4105CHH	sulfate transporter
EY643_RS17830	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
EY643_RS17840	ENOG4105ERG	peptidase m48, ste24p
EY643_RS17855	ENOG4105C5Q	Transcriptional regulator
EY643_RS17860	ENOG4105BZN	citrate synthase
EY643_RS17870	ENOG4105CJ1	ABC, transporter
EY643_RS17875	ENOG4107QWP	ABC-2 type transporter
EY643_RS17890	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
EY643_RS17905	ENOG4108XM1	transcriptional regulator AsnC family
EY643_RS17930	ENOG4108J59	Extracellular solute-binding protein, family 5
EY643_RS17940	ENOG4107QSI	ABC, transporter
EY643_RS17945	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
EY643_RS17950	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
EY643_RS17955	ENOG4108JQ6	ABC transporter
EY643_RS17975	ENOG4105CPN	adenine deaminase
EY643_RS17985	ENOG4105CI2	imidazolone-5-propionate hydrolase
EY643_RS18005	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
EY643_RS18015	ENOG4108MWI	inositol mono-phosphatase
EY643_RS18020	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
EY643_RS18030	ENOG4105CEY	Amp-dependent synthetase and ligase
EY643_RS18050	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
EY643_RS18055	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
EY643_RS18060	ENOG4105C01	Dihydroxy-acid dehydratase
EY643_RS18065	ENOG4105C0A	alcohol dehydrogenase
EY643_RS18085	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
EY643_RS18125	ENOG410846T	CoA-transferase family III
EY643_RS18135	ENOG4106A3M	Cytochrome p-450
EY643_RS18150	ENOG4105CM2	brancheD-chain amino acid aminotransferase
EY643_RS18165	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
EY643_RS18195	ENOG4105CA0	peroxidase
EY643_RS18210	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
EY643_RS18220	ENOG4105DC8	reductase
EY643_RS18225	ENOG4105DA5	(ABC) transporter
EY643_RS18285	ENOG4107ENK	receptor
EY643_RS18295	ENOG4105D6U	Sodium Glutamate Symporter
EY643_RS18315	ENOG4105CNM	Receptor
EY643_RS18325	ENOG4105F2Z	3-oxoadipate enol-lactonase
EY643_RS18335	ENOG4108ESX	Receptor
EY643_RS18340	ENOG4108IA2	Sodium pantothenate symporter
EY643_RS18395	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
EY643_RS18400	ENOG4105CA9	Pyruvate kinase
EY643_RS18405	ENOG4105CHC	glucokinase (EC 2.7.1.2)
EY643_RS18410	ENOG4105DHQ	Histidine kinase
EY643_RS18415	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
EY643_RS18420	ENOG4105VEQ	Cold shock protein
EY643_RS18435	ENOG4109015	Biopolymer transport protein exbD tolR
EY643_RS18440	ENOG4109015	Biopolymer transport protein exbD tolR
EY643_RS18465	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
EY643_RS18470	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
EY643_RS18480	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
EY643_RS18485	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
EY643_RS18500	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
EY643_RS18505	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
EY643_RS18510	ENOG4105D0A	hydroxylase
EY643_RS18515	ENOG4107RAQ	aminopeptidase
EY643_RS18530	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
EY643_RS18540	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
EY643_RS18550	ENOG4105C7B	Threonine dehydratase
EY643_RS18555	ENOG4105E66	phosphoriboisomerase A
EY643_RS18565	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
EY643_RS18570	ENOG4105D7W	serine acetyltransferase
EY643_RS18575	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
EY643_RS18580	ENOG4105BZ8	glutamate synthase
EY643_RS18585	ENOG4105CBC	glutamate synthase
EY643_RS18595	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
EY643_RS18600	ENOG4105E4G	Type IV pilus
EY643_RS18625	ENOG4108JQC	penicillin-binding protein 1A
EY643_RS18630	ENOG4105C6K	Malic enzyme
EY643_RS18645	ENOG4105C25	Primosomal protein n'
EY643_RS18650	ENOG4105C75	arginyL-tRNA synthetase
EY643_RS18660	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
EY643_RS18665	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
EY643_RS18675	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
EY643_RS18685	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
EY643_RS18690	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
EY643_RS18695	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
EY643_RS18700	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
EY643_RS18705	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
EY643_RS18715	ENOG4105D64	Mechanosensitive ion channel
EY643_RS18720	ENOG4105BZ1	(ABC) transporter
EY643_RS18730	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
EY643_RS18735	ENOG4105W8H	transhydrogenase (subunit alpha
EY643_RS18740	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
EY643_RS18750	ENOG4105F2V	VRR-NUC domain-containing protein
EY643_RS18755	ENOG4105D8V	Glucose sorbosone dehydrogenase
EY643_RS18760	ENOG4105DFD	Na H antiporter
EY643_RS18770	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
EY643_RS18775	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
EY643_RS18785	ENOG4105EAC	phosphoserine phosphatase
EY643_RS18795	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
EY643_RS18810	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
EY643_RS18815	ENOG4105CI3	gtp-binding protein typa
EY643_RS18820	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
EY643_RS18825	ENOG4105C5F	glutamine synthetase
EY643_RS18835	ENOG4105CUX	Signal transduction histidine kinase
EY643_RS18840	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
EY643_RS18845	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
EY643_RS18850	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
EY643_RS18855	ENOG4105VW4	glutaredoxin 3
EY643_RS18860	ENOG4105C72	UPF0176 protein
EY643_RS18870	ENOG41063SB	peptidase
EY643_RS18875	ENOG4105CN1	protease
EY643_RS18885	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
EY643_RS18890	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
EY643_RS18895	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
EY643_RS18900	ENOG4105CEN	a g-specific adenine glycosylase
EY643_RS18905	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
EY643_RS18940	ENOG4108J2P	Alpha beta hydrolase fold
EY643_RS18950	ENOG4105CH2	amidohydrolase
EY643_RS18965	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
EY643_RS18970	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
EY643_RS18975	ENOG4105DH7	May be involved in recombination (By similarity)
EY643_RS18980	ENOG4107EFR	Flavocytochrome c
EY643_RS18995	ENOG41083UI	stage II sporulation protein
EY643_RS19000	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
EY643_RS19025	ENOG4105D2N	Aldolase
EY643_RS19030	ENOG4105BZA	Phosphoglycerate kinase
EY643_RS19035	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
EY643_RS19040	ENOG4105CV1	Transketolase (EC 2.2.1.1)
EY643_RS19050	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
EY643_RS19055	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
EY643_RS19060	ENOG4105SYT	Methylenetetrahydrofolate reductase
EY643_RS19065	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
EY643_RS19080	ENOG4105D7Z	glutathione synthase
EY643_RS19090	ENOG4108UJU	UPF0301 protein
EY643_RS19095	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
EY643_RS19100	ENOG4105CZX	twitching motility protein
EY643_RS19105	ENOG4105CZX	twitching motility protein
EY643_RS19110	ENOG4105DFA	alanine racemase domain protein
EY643_RS19115	ENOG4105II7	pyrroline-5-carboxylate reductase
EY643_RS19120	ENOG4108VIA	integral membrane protein
EY643_RS19125	ENOG4105DWV	Homoserine O-trans-acetylase
EY643_RS19130	ENOG4105DWV	Homoserine O-trans-acetylase
EY643_RS19140	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
EY643_RS19145	ENOG4105CSA	Coproporphyrinogen iii oxidase
EY643_RS19150	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
EY643_RS19155	ENOG4105M08	Membrane
EY643_RS19160	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
EY643_RS19165	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
EY643_RS19170	ENOG4105CAK	Cell division ATP-binding protein ftsE
EY643_RS19175	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
EY643_RS19180	ENOG4106H78	methyltransferase
EY643_RS19185	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
EY643_RS19195	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
EY643_RS19200	ENOG4105W0E	50S ribosomal protein L33
EY643_RS19205	ENOG4105KDC	50s ribosomal protein l28
EY643_RS19210	ENOG4105W5Q	DNA repair protein (RadC
EY643_RS19220	ENOG4107QKV	phosphomannomutase
EY643_RS19225	ENOG4105CAS	nag kinase
EY643_RS19230	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
EY643_RS19240	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
EY643_RS19250	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
EY643_RS19255	ENOG4105DSJ	YicC domain protein
EY643_RS19260	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
EY643_RS19265	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
EY643_RS19270	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
EY643_RS19275	ENOG4105KME	endoribonuclease L-psp
EY643_RS19280	ENOG4105C5Q	Transcriptional regulator
EY643_RS19285	ENOG4105CB5	ATP-dependent DNA helicase recG
EY643_RS19295	ENOG4107QZF	nitrite reductase NADPH large subunit
EY643_RS19300	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
EY643_RS19305	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
EY643_RS19320	ENOG4105D1Q	UPF0246 protein
EY643_RS19330	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
EY643_RS19335	ENOG4105NAU	thioesterase Superfamily protein
EY643_RS19340	ENOG4105CH5	extracellular solute-binding protein, family 7
EY643_RS19345	ENOG4105C4R	Atp-dependent dna helicase
EY643_RS19370	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
EY643_RS19375	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
EY643_RS19410	ENOG4105K64	Glycosyl transferase, family 2
EY643_RS19415	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
EY643_RS19445	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
EY643_RS19450	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
EY643_RS19455	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
EY643_RS19460	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
EY643_RS19465	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
EY643_RS19470	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
EY643_RS19475	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
EY643_RS19480	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
EY643_RS19485	ENOG41064MJ	ATP synthase, subunit I
EY643_RS19490	ENOG4105FA0	parb-like partition protein
EY643_RS19495	ENOG4107QJE	Chromosome Partitioning Protein
EY643_RS19505	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
EY643_RS19515	ENOG4105E5G	Alpha beta hydrolase fold
EY643_RS19525	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
EY643_RS19535	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
EY643_RS19540	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EY643_RS19545	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
EY643_RS19550	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
EY643_RS19555	ENOG4105VG0	50S ribosomal protein l34