locus-tag	class	description
GKS42_RS00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
GKS42_RS00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
GKS42_RS00015	ENOG4108J5G	6-phosphogluconate dehydrogenase
GKS42_RS00020	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
GKS42_RS00030	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GKS42_RS00035	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GKS42_RS00065	ENOG4105ME7	Membrane
GKS42_RS00075	ENOG4105C75	arginyL-tRNA synthetase
GKS42_RS00090	ENOG4107U91	Rhomboid family
GKS42_RS00095	ENOG4105ZJT	Cell division protein CrgA
GKS42_RS00105	ENOG4108U4N	(sortase) family
GKS42_RS00120	ENOG4107TPY	serine threonine protein kinase
GKS42_RS00125	ENOG4105CJN	penicillin-binding protein
GKS42_RS00140	ENOG4105HZM	Fha domain containing protein
GKS42_RS00145	ENOG4105TV9	FHA Domain-Containing protein
GKS42_RS00170	ENOG4105I82	acetyl xylan esterase
GKS42_RS00195	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
GKS42_RS00205	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
GKS42_RS00210	ENOG4105DDV	Transcriptional regulator (LacI family
GKS42_RS00235	ENOG4105DKQ	ROK family
GKS42_RS00240	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
GKS42_RS00245	ENOG4105DCG	PHP domain protein
GKS42_RS00250	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
GKS42_RS00285	ENOG4105CQB	FAD linked oxidase domain protein
GKS42_RS00325	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
GKS42_RS00340	ENOG4105ETE	Transcriptional regulator (LacI family
GKS42_RS00345	ENOG4108KJ0	anaerobic glycerol-3-phosphate dehydrogenase, subunit B
GKS42_RS00360	ENOG4105CXK	mandelate racemase muconate lactonizing
GKS42_RS00385	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
GKS42_RS00390	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GKS42_RS00395	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GKS42_RS00405	ENOG4107SCK	Monooxygenase
GKS42_RS00420	ENOG4105DWT	malate dehydrogenase (quinone)
GKS42_RS00430	ENOG4105DFD	Na H antiporter
GKS42_RS00455	ENOG4105TMB	Formate nitrite transporter
GKS42_RS00475	ENOG4105E2D	ec 3.2.1.52
GKS42_RS00485	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
GKS42_RS00490	ENOG41079KZ	Major Facilitator Superfamily
GKS42_RS00510	ENOG4107S5I	aldo keto reductase
GKS42_RS00525	ENOG4105DYW	oxidoreductase
GKS42_RS00545	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
GKS42_RS00560	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
GKS42_RS00570	ENOG4105D7B	Flagellar biosynthesis protein flha
GKS42_RS00575	ENOG4105D00	flagellar biosynthetic protein flhB
GKS42_RS00580	ENOG4108TN6	type iii secretion
GKS42_RS00585	ENOG4105VS8	Flagellar biosynthetic protein fliq
GKS42_RS00590	ENOG4105CN7	Flagellar biosynthetic protein FliP
GKS42_RS00600	ENOG4105DD5	Flagellar motor switch protein
GKS42_RS00610	ENOG4106VK6	Flagellar motor protein
GKS42_RS00615	ENOG4105E14	MotA TolQ exbB proton channel
GKS42_RS00625	ENOG4105BZE	flagellar hook protein, FlgE
GKS42_RS00660	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
GKS42_RS00665	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
GKS42_RS00670	ENOG41084Q6	flagellar hook-basal body complex protein fliE
GKS42_RS00675	ENOG4108ZC9	flagellar basal-body rod protein flgc
GKS42_RS00680	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
GKS42_RS00695	ENOG4107V1F	Flagellar hook-associated 2 domain-containing protein
GKS42_RS00700	ENOG4105I03	Flagellin
GKS42_RS00715	ENOG4105E1Q	flagellar hook-associated protein
GKS42_RS00755	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
GKS42_RS00760	ENOG4105CE4	GlcNAc 6-P deacetylase
GKS42_RS00770	ENOG4105ETE	Transcriptional regulator (LacI family
GKS42_RS00775	ENOG4105DDC	Oxidoreductase domain protein
GKS42_RS00785	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GKS42_RS00790	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GKS42_RS00795	ENOG4108JQ6	ABC transporter
GKS42_RS00805	ENOG4105DDC	Oxidoreductase domain protein
GKS42_RS00810	ENOG4105DK7	lysyl-tRNA synthetase
GKS42_RS00815	ENOG4105E2R	ROK family
GKS42_RS00830	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
GKS42_RS00835	ENOG4108JE9	extracellular solute-binding protein family 1
GKS42_RS00840	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
GKS42_RS00895	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
GKS42_RS00920	ENOG4108Z5K	methylglyoxal synthase
GKS42_RS00940	ENOG4108JE9	extracellular solute-binding protein family 1
GKS42_RS00945	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
GKS42_RS00990	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
GKS42_RS01010	ENOG4105DKQ	ROK family
GKS42_RS01025	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
GKS42_RS01060	ENOG4105CQB	FAD linked oxidase domain protein
GKS42_RS01090	ENOG4108KE4	O-methyltransferase
GKS42_RS01105	ENOG4105CQ7	ATP-dependent helicase
GKS42_RS01150	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
GKS42_RS01220	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
GKS42_RS01230	ENOG4105ETE	Transcriptional regulator (LacI family
GKS42_RS01235	ENOG4105C2C	drug resistance transporter, Bcr CflA
GKS42_RS01245	ENOG4108ZGX	Histidine kinase
GKS42_RS01250	ENOG4105WH1	Two component transcriptional regulator luxr family
GKS42_RS01270	ENOG4105CGU	Enoyl-CoA hydratase
GKS42_RS01275	ENOG4105BZN	citrate synthase
GKS42_RS01280	ENOG4105BZN	citrate synthase
GKS42_RS01285	ENOG4105C5X	domain protein
GKS42_RS01300	ENOG4105CJ1	ABC, transporter
GKS42_RS01330	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
GKS42_RS01345	ENOG4107HP6	Transcriptional regulator
GKS42_RS01360	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
GKS42_RS01370	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
GKS42_RS01400	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
GKS42_RS01430	ENOG4105WH1	Two component transcriptional regulator luxr family
GKS42_RS01435	ENOG4105ENE	Histidine kinase
GKS42_RS01440	ENOG4105DUX	Transporter
GKS42_RS01465	ENOG4105C26	Dehydrogenase
GKS42_RS01480	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
GKS42_RS01490	ENOG4105D9R	oxidoreductase
GKS42_RS01495	ENOG4105ETE	Transcriptional regulator (LacI family
GKS42_RS01500	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
GKS42_RS01530	ENOG4105CIS	alcohol dehydrogenase
GKS42_RS01535	ENOG4105E0X	reductase
GKS42_RS01540	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
GKS42_RS01555	ENOG4105CXK	mandelate racemase muconate lactonizing
GKS42_RS01585	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
GKS42_RS01590	ENOG4105DRS	transport system, permease
GKS42_RS01595	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
GKS42_RS01620	ENOG4105I82	acetyl xylan esterase
GKS42_RS01660	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
GKS42_RS01685	ENOG4105BZ1	(ABC) transporter
GKS42_RS01725	ENOG4105C7I	Dehydrogenase
GKS42_RS01730	ENOG4108YYC	ycei family
GKS42_RS01740	ENOG4105DEN	Luciferase family
GKS42_RS01800	ENOG4105E0A	ABC, transporter
GKS42_RS01805	ENOG4105TVJ	transport system, permease
GKS42_RS01810	ENOG4105DQ5	transport system permease protein
GKS42_RS01820	ENOG4105PEC	Iron-enterobactin transporter periplasmic binding protein
GKS42_RS01840	ENOG4105CPN	adenine deaminase
GKS42_RS01860	ENOG41073TP	transcriptional regulator
GKS42_RS01870	ENOG4108478	ec 3.2.1.18
GKS42_RS01885	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
GKS42_RS01890	ENOG4108478	ec 3.2.1.18
GKS42_RS01905	ENOG4105BZ1	(ABC) transporter
GKS42_RS01945	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
GKS42_RS01950	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
GKS42_RS01980	ENOG4108VK3	Cupin 2 Conserved Barrel Domain Protein
GKS42_RS01990	ENOG4105BZU	Histidine kinase
GKS42_RS01995	ENOG4105KCT	ABC transporter
GKS42_RS02000	ENOG4108M15	ABC transporter
GKS42_RS02020	ENOG4105EYF	MMPL domain protein
GKS42_RS02035	ENOG4105HS2	Arsenate reductase
GKS42_RS02045	ENOG4105DDI	hemolysin-type calcium-binding region
GKS42_RS02050	ENOG4105CXK	mandelate racemase muconate lactonizing
GKS42_RS02055	ENOG4105EG2	ABC transporter, permease
GKS42_RS02060	ENOG4105HS6	binding-protein-dependent transport systems inner membrane Component
GKS42_RS02075	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
GKS42_RS02100	ENOG4105CVK	Glutamate decarboxylase
GKS42_RS02145	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
GKS42_RS02155	ENOG4105FKQ	transcriptional regulator
GKS42_RS02180	ENOG4105CK5	oxidoreductase
GKS42_RS02195	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
GKS42_RS02210	ENOG4105CV8	reductase
GKS42_RS02215	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
GKS42_RS02235	ENOG4108EIM	Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities (By similarity)
GKS42_RS02245	ENOG4105CMT	Dihydroxyacetone kinase
GKS42_RS02250	ENOG4107YVI	ribose 5-phosphate isomerase
GKS42_RS02255	ENOG4108MKX	Triose-phosphate isomerase
GKS42_RS02290	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
GKS42_RS02305	ENOG4105ETE	Transcriptional regulator (LacI family
GKS42_RS02320	ENOG41063TF	transcriptional regulator (AraC
GKS42_RS02335	ENOG4105CQB	FAD linked oxidase domain protein
GKS42_RS02345	ENOG4108YZG	isomerase
GKS42_RS02360	ENOG4105ETE	Transcriptional regulator (LacI family
GKS42_RS02365	ENOG4105CHR	reductase
GKS42_RS02370	ENOG4105E39	Enoyl-CoA hydratase
GKS42_RS02375	ENOG4108IIG	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity)
GKS42_RS02400	ENOG4105C0A	alcohol dehydrogenase
GKS42_RS02405	ENOG4105DG4	malate L-lactate dehydrogenase
GKS42_RS02410	ENOG4107HP6	Transcriptional regulator
GKS42_RS02420	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
GKS42_RS02425	ENOG4105CXK	mandelate racemase muconate lactonizing
GKS42_RS02435	ENOG4105DIA	mandelate racemase muconate lactonizing
GKS42_RS02445	ENOG4107S9F	NmrA family
GKS42_RS02465	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GKS42_RS02470	ENOG4105MKU	Transcriptional regulator
GKS42_RS02475	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
GKS42_RS02485	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
GKS42_RS02495	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
GKS42_RS02505	ENOG4105CHR	reductase
GKS42_RS02510	ENOG4105CPQ	Dehydrogenase
GKS42_RS02515	ENOG4107EJG	GntR family transcriptional regulator
GKS42_RS02520	ENOG4105DIA	mandelate racemase muconate lactonizing
GKS42_RS02525	ENOG4105JXH	GntR family transcriptional regulator
GKS42_RS02540	ENOG4105KT7	mgtC SapB transporter
GKS42_RS02555	ENOG4105CZN	Potassium uptake protein
GKS42_RS02560	ENOG4107ZYR	domain protein
GKS42_RS02610	ENOG4105RWF	major outer membrane protein OmpA
GKS42_RS02670	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
GKS42_RS02710	ENOG4105CI2	imidazolone-5-propionate hydrolase
GKS42_RS02715	ENOG4105CGP	Urocanate hydratase
GKS42_RS02725	ENOG4105C84	Histidine ammonia-lyase
GKS42_RS02730	ENOG4105NAE	bifunctional deaminase-reductase domain protein
GKS42_RS02750	ENOG4105CHP	RNA polymerase
GKS42_RS02755	ENOG4108YRB	methyltransferase
GKS42_RS02775	ENOG41066UZ	arginase EC 3.5.3.1
GKS42_RS02800	ENOG4105HRU	Glyoxalase Bleomycin resistance protein (Dioxygenase
GKS42_RS02820	ENOG41082BM	Transcriptional regulator, arsr family
GKS42_RS02835	ENOG4105ETE	Transcriptional regulator (LacI family
GKS42_RS02845	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
GKS42_RS02850	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
GKS42_RS02855	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
GKS42_RS02895	ENOG4105BZU	Histidine kinase
GKS42_RS02915	ENOG4105ETE	Transcriptional regulator (LacI family
GKS42_RS02925	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
GKS42_RS02930	ENOG4105DRS	transport system, permease
GKS42_RS02970	ENOG4105CHR	reductase
GKS42_RS02975	ENOG41073TP	transcriptional regulator
GKS42_RS02990	ENOG4105HS6	binding-protein-dependent transport systems inner membrane Component
GKS42_RS02995	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
GKS42_RS03000	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
GKS42_RS03005	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
GKS42_RS03010	ENOG4105CXK	mandelate racemase muconate lactonizing
GKS42_RS03020	ENOG4105ETE	Transcriptional regulator (LacI family
GKS42_RS03025	ENOG4105WH1	Two component transcriptional regulator luxr family
GKS42_RS03030	ENOG4105BZU	Histidine kinase
GKS42_RS03050	ENOG4108JNI	Alpha beta hydrolase
GKS42_RS03065	ENOG4105CH2	amidohydrolase
GKS42_RS03070	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
GKS42_RS03075	ENOG4108IJG	ABC transporter substrate-binding protein
GKS42_RS03090	ENOG4105E98	transcriptional regulator DeoR family
GKS42_RS03095	ENOG4105DZC	cytosine deaminase
GKS42_RS03120	ENOG4108HHA	Transketolase
GKS42_RS03125	ENOG4108IUS	Transketolase
GKS42_RS03130	ENOG4105C5I	Dehydrogenase
GKS42_RS03145	ENOG4105DTQ	mandelate racemase muconate lactonizing
GKS42_RS03160	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
GKS42_RS03165	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
GKS42_RS03180	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
GKS42_RS03185	ENOG4107Z96	xylose isomerase
GKS42_RS03190	ENOG4105DKT	Transcriptional regulator
GKS42_RS03255	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
GKS42_RS03260	ENOG4108JP0	extracellular solute-binding protein family 1
GKS42_RS03280	ENOG4107SET	aldo keto reductase
GKS42_RS03310	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
GKS42_RS03320	ENOG4105QNJ	serralysin (EC 3.4.24.40)
GKS42_RS03335	ENOG4108JQ7	(ABC) transporter
GKS42_RS03345	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GKS42_RS03370	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
GKS42_RS03380	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
GKS42_RS03390	ENOG410804X	Transcriptional regulator
GKS42_RS03395	ENOG4105CV8	reductase
GKS42_RS03400	ENOG4105ETE	Transcriptional regulator (LacI family
GKS42_RS03405	ENOG4106Z5D	Glycoside Hydrolase Family 43
GKS42_RS03415	ENOG4105E0A	ABC, transporter
GKS42_RS03420	ENOG4105TVJ	transport system, permease
GKS42_RS03425	ENOG4105DQ5	transport system permease protein
GKS42_RS03440	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
GKS42_RS03480	ENOG4105BZU	Histidine kinase
GKS42_RS03500	ENOG4105F27	Major Facilitator
GKS42_RS03550	ENOG4105CPQ	Dehydrogenase
GKS42_RS03565	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
GKS42_RS03570	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
GKS42_RS03575	ENOG4105DEF	Extracellular solute-binding protein, family 5
GKS42_RS03585	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GKS42_RS03640	ENOG4105CWX	Alpha-1,2-mannosidase
GKS42_RS03660	ENOG41060NJ	transcriptional regulator
GKS42_RS03675	ENOG4107HP6	Transcriptional regulator
GKS42_RS03685	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GKS42_RS03695	ENOG4108JQ7	(ABC) transporter
GKS42_RS03705	ENOG4105CVJ	phosphoglycerate mutase
GKS42_RS03715	ENOG4105DEF	Extracellular solute-binding protein, family 5
GKS42_RS03720	ENOG4108MDK	Dehydrogenase
GKS42_RS03725	ENOG4105EF1	ribulokinase
GKS42_RS03730	ENOG4108KD5	ADP-ribosylation crystallin J1
GKS42_RS03735	ENOG4107TE5	Lipid kinase
GKS42_RS03740	ENOG4108YZN	class I peptide chain release factor
GKS42_RS03775	ENOG4108DNI	pyridine nucleotide-disulfide oxidoreductase
GKS42_RS03790	ENOG4108RFG	Tetr family transcriptional regulator
GKS42_RS03800	ENOG4105C7K	acetolactate synthase
GKS42_RS03820	ENOG4105D78	K07001 NTE family protein
GKS42_RS03830	ENOG4107VXZ	Hydrolase
GKS42_RS03890	ENOG4105EC2	ftsk spoIIIe
GKS42_RS03900	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
GKS42_RS03915	ENOG4105HHS	UPF0256 protein
GKS42_RS03925	ENOG4105CUV	Homoserine Kinase
GKS42_RS03940	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
GKS42_RS03945	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
GKS42_RS03960	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
GKS42_RS03970	ENOG4107TFQ	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
GKS42_RS03990	ENOG4105ENH	Sulfatase
GKS42_RS04000	ENOG4105E6M	Sulphatase-modifying factor protein
GKS42_RS04005	ENOG4105C7Z	Conserved Protein
GKS42_RS04015	ENOG4105C32	Amino acid ABC transporter (Permease)
GKS42_RS04020	ENOG4105C0Z	ABC transporter
GKS42_RS04025	ENOG4108IV0	ABC, transporter
GKS42_RS04060	ENOG4105VEQ	Cold shock protein
GKS42_RS04065	ENOG4107TE5	Lipid kinase
GKS42_RS04070	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
GKS42_RS04075	ENOG4108KP7	hydrolase
GKS42_RS04080	ENOG4105ETE	Transcriptional regulator (LacI family
GKS42_RS04085	ENOG4105EPJ	extracellular solute-binding protein family 1
GKS42_RS04090	ENOG4105S9S	Binding-protein-dependent transport systems, inner membrane component
GKS42_RS04095	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
GKS42_RS04100	ENOG4108VC7	Protein of unknown function (DUF2587)
GKS42_RS04105	ENOG4107QKS	N-acylglucosamine 2-epimerase
GKS42_RS04115	ENOG4105DRS	transport system, permease
GKS42_RS04120	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
GKS42_RS04130	ENOG4105ETE	Transcriptional regulator (LacI family
GKS42_RS04160	ENOG4105CPQ	Dehydrogenase
GKS42_RS04165	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
GKS42_RS04170	ENOG4105CPC	Aldo Keto reductase
GKS42_RS04175	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
GKS42_RS04185	ENOG4105KV4	Transcriptional regulator
GKS42_RS04225	ENOG4105DHU	Bile acid
GKS42_RS04240	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
GKS42_RS04260	ENOG4105Y3U	Transglycosylase-associated protein
GKS42_RS04275	ENOG4105DJ2	Major Facilitator Superfamily
GKS42_RS04285	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
GKS42_RS04315	ENOG4105CHP	RNA polymerase
GKS42_RS04320	ENOG4105GRZ	Ycii-related protein
GKS42_RS04325	ENOG4105CUV	Homoserine Kinase
GKS42_RS04360	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GKS42_RS04410	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
GKS42_RS04430	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
GKS42_RS04435	ENOG4107TTD	cytosine deaminase
GKS42_RS04445	ENOG4108I05	Binding-protein-dependent transport systems, inner membrane component
GKS42_RS04465	ENOG4107SCA	Formamidase (EC 3.5.1.49)
GKS42_RS04475	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
GKS42_RS04480	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
GKS42_RS04495	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
GKS42_RS04505	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
GKS42_RS04510	ENOG4108UMI	ABC transporter, permease
GKS42_RS04515	ENOG4105D01	(LipO)protein
GKS42_RS04570	ENOG4105C9B	Cysteine desulfurase
GKS42_RS04575	ENOG4107SM8	Adenylate Guanylate cyclase
GKS42_RS04600	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
GKS42_RS04605	ENOG4108Z6B	deaminase
GKS42_RS04625	ENOG4105ETE	Transcriptional regulator (LacI family
GKS42_RS04645	ENOG4105ETE	Transcriptional regulator (LacI family
GKS42_RS04650	ENOG4105DDC	Oxidoreductase domain protein
GKS42_RS04680	ENOG4105CHR	reductase
GKS42_RS04685	ENOG4107S3R	L-aspartate oxidase
GKS42_RS04690	ENOG4105CT3	Monooxygenase
GKS42_RS04770	ENOG4105C93	Xylose Isomerase
GKS42_RS04790	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
GKS42_RS04795	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
GKS42_RS04805	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
GKS42_RS04815	ENOG4105E4I	Glycoside hydrolase family 28
GKS42_RS04820	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
GKS42_RS04825	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
GKS42_RS04830	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
GKS42_RS04835	ENOG4105DKT	Transcriptional regulator
GKS42_RS04870	ENOG4105E59	Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity)
GKS42_RS04875	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
GKS42_RS04880	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
GKS42_RS04890	ENOG4105II7	pyrroline-5-carboxylate reductase
GKS42_RS04895	ENOG4107ZYR	domain protein
GKS42_RS04905	ENOG4105DGU	Histone deacetylase
GKS42_RS04930	ENOG4108YYC	ycei family
GKS42_RS04940	ENOG4108RH7	phosphoglycerate mutase
GKS42_RS04960	ENOG4105CRE	cytochrome C
GKS42_RS04995	ENOG4105EEQ	Na H antiporter
GKS42_RS05005	ENOG4107SIQ	Naphthoate synthase
GKS42_RS05010	ENOG4107TCW	O-succinylbenzoate synthase
GKS42_RS05015	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
GKS42_RS05025	ENOG4105E4F	Isochorismate synthase
GKS42_RS05030	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
GKS42_RS05045	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GKS42_RS05050	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GKS42_RS05055	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GKS42_RS05065	ENOG4107QIZ	NADH dehydrogenase
GKS42_RS05070	ENOG4108IEH	NADH dehydrogenase subunit g
GKS42_RS05075	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
GKS42_RS05080	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GKS42_RS05085	ENOG4107UFS	subunit j
GKS42_RS05090	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GKS42_RS05095	ENOG4105D65	subunit l
GKS42_RS05105	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GKS42_RS05115	ENOG4105EC2	ftsk spoIIIe
GKS42_RS05165	ENOG4108PZM	peptidase S8 and S53, subtilisin, kexin, sedolisin
GKS42_RS05185	ENOG4105D0M	Protease HtpX homolog
GKS42_RS05190	ENOG4108VPT	UPF0234 protein
GKS42_RS05210	ENOG4105WDJ	50S ribosomal protein L33
GKS42_RS05215	ENOG410900P	UPF0336 protein
GKS42_RS05225	ENOG4105ETE	Transcriptional regulator (LacI family
GKS42_RS05230	ENOG4106UW1	Major Facilitator superfamily
GKS42_RS05235	ENOG4107R4N	Cell wall formation (By similarity)
GKS42_RS05275	ENOG4105ETX	regulatoR
GKS42_RS05280	ENOG41062D9	Histidine kinase
GKS42_RS05290	ENOG410683Z	Preprotein translocase SecE subunit
GKS42_RS05300	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
GKS42_RS05305	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
GKS42_RS05310	ENOG4108VZM	50s ribosomal protein L10
GKS42_RS05315	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
GKS42_RS05320	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GKS42_RS05325	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GKS42_RS05335	ENOG4105CJ1	ABC, transporter
GKS42_RS05360	ENOG4105CT4	transporter
GKS42_RS05365	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
GKS42_RS05370	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
GKS42_RS05375	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
GKS42_RS05380	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
GKS42_RS05390	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
GKS42_RS05395	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
GKS42_RS05400	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
GKS42_RS05405	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
GKS42_RS05410	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GKS42_RS05415	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
GKS42_RS05420	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
GKS42_RS05425	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
GKS42_RS05430	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
GKS42_RS05435	ENOG41082SA	50s ribosomal protein l29
GKS42_RS05440	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
GKS42_RS05445	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
GKS42_RS05450	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
GKS42_RS05455	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GKS42_RS05460	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
GKS42_RS05465	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
GKS42_RS05470	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
GKS42_RS05480	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
GKS42_RS05485	ENOG410849U	50S ribosomal protein L30
GKS42_RS05490	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
GKS42_RS05495	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
GKS42_RS05500	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
GKS42_RS05510	ENOG4105D3Q	Sugar transferase
GKS42_RS05515	ENOG4108RM3	Phosphatase with a broad specificity. Its primary physiological function is to dephosphorylate 3'-phosphoadenosine 5'-phosphate (PAP) and 3'-phosphoadenosine 5'-phosphosulfate (PAPS). Thus, plays a role in mycobacterial sulfur metabolism, since it can serve as a key regulator of the sulfate assimilation pathway by controlling the pools of PAP and PAPS in the cell. To a lesser extent, is also able to hydrolyze inositol 1-phosphate (I- 1-P), fructose 1,6-bisphosphate (FBP) (to fructose 6-phosphate (F- 6-P)) and AMP in vitro, but this might has no significance in vivo
GKS42_RS05520	ENOG41061ZR	Transcriptional regulator
GKS42_RS05530	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
GKS42_RS05540	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GKS42_RS05545	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
GKS42_RS05550	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GKS42_RS05555	ENOG4108ZT0	50S ribosomal protein l17
GKS42_RS05560	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
GKS42_RS05570	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
GKS42_RS05580	ENOG4105C5H	ABC transporter
GKS42_RS05585	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
GKS42_RS05590	ENOG4108UJD	30S ribosomal protein S9
GKS42_RS05595	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
GKS42_RS05600	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
GKS42_RS05635	ENOG4105EBR	Carboxylesterase
GKS42_RS05640	ENOG4105CS9	pantothenic acid kinase
GKS42_RS05645	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
GKS42_RS05650	ENOG41082KK	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
GKS42_RS05685	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GKS42_RS05700	ENOG4105VUN	Transcriptional regulator
GKS42_RS05710	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
GKS42_RS05725	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
GKS42_RS05730	ENOG4105KIU	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
GKS42_RS05735	ENOG4107X2D	transcriptional regulator, merr family
GKS42_RS05740	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
GKS42_RS05755	ENOG4107QVP	Dehydrogenase
GKS42_RS05775	ENOG4105C5I	Dehydrogenase
GKS42_RS05780	ENOG4105CMD	Transcriptional regulator, GntR family
GKS42_RS05790	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
GKS42_RS05795	ENOG4105DRS	transport system, permease
GKS42_RS05815	ENOG4105C9Q	fumarate hydratase class II
GKS42_RS05830	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
GKS42_RS05850	ENOG4105BZ1	(ABC) transporter
GKS42_RS05855	ENOG4105BZ1	(ABC) transporter
GKS42_RS05870	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
GKS42_RS05875	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
GKS42_RS05900	ENOG4105WH1	Two component transcriptional regulator luxr family
GKS42_RS05915	ENOG4105CPC	Aldo Keto reductase
GKS42_RS05920	ENOG4105VUF	Transcriptional regulator
GKS42_RS05955	ENOG4105EXC	Acyl-transferase
GKS42_RS05960	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
GKS42_RS05995	ENOG4105DC1	bifunctional purine biosynthesis protein purh
GKS42_RS06025	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
GKS42_RS06055	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
GKS42_RS06070	ENOG4105CGK	Exodeoxyribonuclease III
GKS42_RS06090	ENOG4107RBB	ABC transporter, permease
GKS42_RS06095	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GKS42_RS06115	ENOG4105CFG	Acts as a chaperone (By similarity)
GKS42_RS06125	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
GKS42_RS06140	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
GKS42_RS06145	ENOG4105DU0	nucleoside hydrolase
GKS42_RS06165	ENOG4108RVA	ribokinase
GKS42_RS06170	ENOG4105ETE	Transcriptional regulator (LacI family
GKS42_RS06175	ENOG4107RM1	amidohydrolase
GKS42_RS06180	ENOG4105DIH	basic membrane
GKS42_RS06185	ENOG4108JQ9	ABC transporter
GKS42_RS06190	ENOG4105UIB	(ABC) transporter
GKS42_RS06225	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
GKS42_RS06235	ENOG4106PMH	Extracellular solute-binding protein family 3
GKS42_RS06240	ENOG4105E5Q	amino acid AbC transporter
GKS42_RS06270	ENOG4105C26	Dehydrogenase
GKS42_RS06275	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
GKS42_RS06290	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
GKS42_RS06310	ENOG4108IV0	ABC, transporter
GKS42_RS06315	ENOG4105C0Z	ABC transporter
GKS42_RS06320	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
GKS42_RS06325	ENOG4105C32	Amino acid ABC transporter (Permease)
GKS42_RS06345	ENOG4107R4C	succinyl-diaminopimelate desuccinylase
GKS42_RS06350	ENOG4108URH	decarboxylase
GKS42_RS06365	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
GKS42_RS06380	ENOG4105DU6	RNA polymerase
GKS42_RS06395	ENOG4105UTW	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
GKS42_RS06400	ENOG4105D1F	ATP-binding protein
GKS42_RS06410	ENOG4105CJW	magnesium transporter
GKS42_RS06425	ENOG4107T6F	Xaa-Pro aminopeptidase
GKS42_RS06430	ENOG4105DB7	PHP domain protein
GKS42_RS06435	ENOG41081FY	multiple antibiotic resistance (MarC)-related
GKS42_RS06440	ENOG4105C1J	atp-dependent rna helicase
GKS42_RS06465	ENOG4105C4R	Atp-dependent dna helicase
GKS42_RS06475	ENOG4105E09	nadh pyrophosphatase
GKS42_RS06490	ENOG4105WBQ	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
GKS42_RS06520	ENOG4105DJZ	UPF0182 protein
GKS42_RS06545	ENOG4105QE3	oxidoreductase
GKS42_RS06560	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
GKS42_RS06580	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
GKS42_RS06620	ENOG4105C26	Dehydrogenase
GKS42_RS06630	ENOG4105CJ1	ABC, transporter
GKS42_RS06645	ENOG4105E2A	Dehydrogenase
GKS42_RS06660	ENOG4105ECQ	AraC Family Transcriptional Regulator
GKS42_RS06680	ENOG4105ETE	Transcriptional regulator (LacI family
GKS42_RS06685	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
GKS42_RS06720	ENOG4105EC2	ftsk spoIIIe
GKS42_RS06735	ENOG4105C9U	ATP-dependent DNA helicase RecQ
GKS42_RS06750	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GKS42_RS06755	ENOG4105WH1	Two component transcriptional regulator luxr family
GKS42_RS06765	ENOG4107T4Z	adenosine kinase
GKS42_RS06770	ENOG4108RAV	Conserved protein
GKS42_RS06810	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
GKS42_RS06830	ENOG4108HKT	sucrose-6-phosphate hydrolase
GKS42_RS06835	ENOG4105DRS	transport system, permease
GKS42_RS06840	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
GKS42_RS06890	ENOG4105CVK	Glutamate decarboxylase
GKS42_RS06910	ENOG4105DRP	amino acid AbC transporter
GKS42_RS06925	ENOG4105C2C	drug resistance transporter, Bcr CflA
GKS42_RS06930	ENOG4105CK7	Sodium proline symporter
GKS42_RS06935	ENOG4107RGH	Aldehyde dehydrogenase
GKS42_RS06950	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
GKS42_RS06955	ENOG4105E8G	Major facilitator Superfamily
GKS42_RS06960	ENOG4108J2P	Alpha beta hydrolase fold
GKS42_RS06975	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
GKS42_RS06980	ENOG4105CAK	Cell division ATP-binding protein ftsE
GKS42_RS06985	ENOG4107RYD	Part of the ABC transporter FtsEX involved in cellular division (By similarity)
GKS42_RS06995	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
GKS42_RS07045	ENOG4107UNZ	domain protein
GKS42_RS07350	ENOG41084I7	Alpha-galactosidase. Removes both branched alpha-1,3- linked galactose residues of blood group B antigens and linear alpha-1,3-linked galactose structures
GKS42_RS07365	ENOG41082YX	Transcriptional regulator, arsr family
GKS42_RS07370	ENOG4105EFJ	Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity)
GKS42_RS07375	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
GKS42_RS07380	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
GKS42_RS07400	ENOG4108426	dNA-binding protein
GKS42_RS07435	ENOG4105KEN	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
GKS42_RS07455	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
GKS42_RS07460	ENOG4105DEN	Luciferase family
GKS42_RS07465	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
GKS42_RS07470	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
GKS42_RS07480	ENOG4105DEI	Mannitol dehydrogenase
GKS42_RS07485	ENOG4105DKT	Transcriptional regulator
GKS42_RS07515	ENOG4105K5X	acetyltransferase
GKS42_RS07530	ENOG4105CSM	endonuclease III
GKS42_RS07545	ENOG4108V06	Glutathione peroxidase
GKS42_RS07690	ENOG4105E4C	Lytic transglycosylase catalytic
GKS42_RS07835	ENOG4105E4C	Lytic transglycosylase catalytic
GKS42_RS07855	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GKS42_RS07900	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
GKS42_RS07945	ENOG4105DQ5	transport system permease protein
GKS42_RS07950	ENOG4105EHG	Permease protein
GKS42_RS07955	ENOG4105E0A	ABC, transporter
GKS42_RS07985	ENOG4108ZHJ	Organic hydroperoxide resistance protein
GKS42_RS08030	ENOG4105H3G	oxidoreductase
GKS42_RS08070	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
GKS42_RS08075	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GKS42_RS08080	ENOG4106KNT	transcriptional regulator
GKS42_RS08090	ENOG4105ETE	Transcriptional regulator (LacI family
GKS42_RS08105	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
GKS42_RS08110	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
GKS42_RS08125	ENOG4105C29	acyl-CoA thioesterase
GKS42_RS08135	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
GKS42_RS08145	ENOG4105D8X	mechanosensitive ion channel
GKS42_RS08155	ENOG4105C5Y	PTS System
GKS42_RS08165	ENOG4105JAB	phenazine biosynthesis protein, phzf family
GKS42_RS08180	ENOG4105MC2	DSBA oxidoreductase
GKS42_RS08205	ENOG4105C9K	Endothelin-converting enzyme 1
GKS42_RS08215	ENOG4108YZG	isomerase
GKS42_RS08235	ENOG4105D7W	serine acetyltransferase
GKS42_RS08265	ENOG41080FR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
GKS42_RS08270	ENOG4105NRA	50s ribosomal protein l31 type b
GKS42_RS08310	ENOG4107QWG	2-Nitropropane dioxygenase
GKS42_RS08330	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
GKS42_RS08335	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
GKS42_RS08340	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
GKS42_RS08345	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
GKS42_RS08360	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GKS42_RS08370	ENOG4108JQ6	ABC transporter
GKS42_RS08375	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
GKS42_RS08385	ENOG4105FBW	Monooxygenase
GKS42_RS08485	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
GKS42_RS08490	ENOG4107QND	Nitrite extrusion protein
GKS42_RS08495	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
GKS42_RS08500	ENOG4108IFG	nitrite reductase, (NAD(P)H)
GKS42_RS08505	ENOG4107QZF	nitrite reductase NADPH large subunit
GKS42_RS08510	ENOG4107QZF	nitrite reductase NADPH large subunit
GKS42_RS08535	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
GKS42_RS08540	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
GKS42_RS08550	ENOG410905P	Pyridoxamine 5-phosphate
GKS42_RS08575	ENOG4105CPF	Cell wall formation (By similarity)
GKS42_RS08600	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
GKS42_RS08610	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
GKS42_RS08615	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
GKS42_RS08625	ENOG4105EDK	PfkB domain protein
GKS42_RS08630	ENOG4105F8D	glycoside hydrolase family 4
GKS42_RS08640	ENOG4105W0E	50S ribosomal protein L33
GKS42_RS08645	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
GKS42_RS08665	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
GKS42_RS08670	ENOG4105E0A	ABC, transporter
GKS42_RS08675	ENOG4108IHU	transport system permease protein
GKS42_RS08710	ENOG4107RNN	dihydropyrimidinase (EC 3.5.2.2)
GKS42_RS08720	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
GKS42_RS08740	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
GKS42_RS08750	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
GKS42_RS08770	ENOG4105WH1	Two component transcriptional regulator luxr family
GKS42_RS08780	ENOG4105C1G	acyl-Coa dehydrogenase
GKS42_RS08790	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
GKS42_RS08805	ENOG4105KVH	Transcriptional regulator
GKS42_RS08815	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
GKS42_RS08830	ENOG4105D03	DNA-3-methyladenine glycosylase II
GKS42_RS08835	ENOG4105CPQ	Dehydrogenase
GKS42_RS08870	ENOG4105ECQ	AraC Family Transcriptional Regulator
GKS42_RS08880	ENOG4108IXY	short-chain dehydrogenase reductase
GKS42_RS08900	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
GKS42_RS08905	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
GKS42_RS08965	ENOG4105CMT	Dihydroxyacetone kinase
GKS42_RS08970	ENOG4108UTZ	Dihydroxyacetone kinase
GKS42_RS08975	ENOG4105VDH	Dihydroxyacetone kinase
GKS42_RS08990	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
GKS42_RS09005	ENOG4105N2W	Transcriptional regulator
GKS42_RS09015	ENOG4105C26	Dehydrogenase
GKS42_RS09020	ENOG4105WH1	Two component transcriptional regulator luxr family
GKS42_RS09025	ENOG4108ZGX	Histidine kinase
GKS42_RS09030	ENOG4105CJ1	ABC, transporter
GKS42_RS09040	ENOG4105CQC	Prephenate dehydratase
GKS42_RS09060	ENOG4105C19	ABC transporter
GKS42_RS09085	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
GKS42_RS09110	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GKS42_RS09125	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
GKS42_RS09145	ENOG4105CZV	ABC transporter
GKS42_RS09155	ENOG4105CJ1	ABC, transporter
GKS42_RS09165	ENOG4105K5M	30s ribosomal protein S16
GKS42_RS09170	ENOG41082KU	UPF0109 protein
GKS42_RS09175	ENOG4107XUM	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
GKS42_RS09180	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
GKS42_RS09185	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
GKS42_RS09190	ENOG4107QYR	Signal peptidase i
GKS42_RS09195	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GKS42_RS09205	ENOG41080R2	UPF0102 protein
GKS42_RS09220	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GKS42_RS09235	ENOG4105CE9	30S ribosomal protein S2
GKS42_RS09240	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
GKS42_RS09245	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
GKS42_RS09250	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
GKS42_RS09255	ENOG4105KNE	Phosphatidate cytidylyltransferase
GKS42_RS09265	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
GKS42_RS09275	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
GKS42_RS09280	ENOG4105DZP	Membrane-associated zinc metalloprotease
GKS42_RS09285	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
GKS42_RS09300	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
GKS42_RS09310	ENOG4107Z1I	Required for maturation of 30S ribosomal subunits (By similarity)
GKS42_RS09325	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
GKS42_RS09330	ENOG4107ZPY	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
GKS42_RS09335	ENOG4105C57	major facilitator superfamily
GKS42_RS09345	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
GKS42_RS09365	ENOG4105NTW	Transcriptional regulator
GKS42_RS09370	ENOG4105DTN	riboflavin biosynthesis protein ribF
GKS42_RS09375	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
GKS42_RS09380	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
GKS42_RS09385	ENOG4105C1V	Peptidase, M16
GKS42_RS09390	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
GKS42_RS09405	ENOG4108TEB	UPF0114 protein
GKS42_RS09410	ENOG4105BZ1	(ABC) transporter
GKS42_RS09430	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
GKS42_RS09440	ENOG4105CK5	oxidoreductase
GKS42_RS09455	ENOG4105CN5	Metallo-Beta-Lactamase
GKS42_RS09480	ENOG4105VMP	Transcriptional regulator
GKS42_RS09495	ENOG4105CEV	competence damage-inducible protein
GKS42_RS09510	ENOG4105CXK	mandelate racemase muconate lactonizing
GKS42_RS09515	ENOG4105ETE	Transcriptional regulator (LacI family
GKS42_RS09520	ENOG4108S0J	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'- phosphates (By similarity)
GKS42_RS09525	ENOG4107QRT	dEAD DEAH box helicase
GKS42_RS09550	ENOG4105E9Z	Nad-dependent epimerase dehydratase
GKS42_RS09580	ENOG4107RUY	(E1 component), alpha subunit
GKS42_RS09585	ENOG4105CPP	Dehydrogenase, E1 component
GKS42_RS09610	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
GKS42_RS09620	ENOG4105ETE	Transcriptional regulator (LacI family
GKS42_RS09635	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
GKS42_RS09640	ENOG4105KC9	Modulates RecA activity (By similarity)
GKS42_RS09650	ENOG4105DRP	amino acid AbC transporter
GKS42_RS09655	ENOG4108Q1T	ABC transporter
GKS42_RS09660	ENOG4107UBR	Extracellular solute-binding protein family 3
GKS42_RS09665	ENOG4105CDA	abc transporter atp-binding protein
GKS42_RS09670	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
GKS42_RS09685	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
GKS42_RS09690	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
GKS42_RS09695	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
GKS42_RS09700	ENOG4107Y49	methyltransferase
GKS42_RS09705	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
GKS42_RS09730	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
GKS42_RS09740	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
GKS42_RS09745	ENOG4105CPC	Aldo Keto reductase
GKS42_RS09750	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
GKS42_RS09765	ENOG4108JQ1	Dehydrogenase
GKS42_RS09780	ENOG4105VEQ	Cold shock protein
GKS42_RS09815	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
GKS42_RS09820	ENOG4108V6E	Cell division protein mraZ
GKS42_RS09825	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
GKS42_RS09835	ENOG4105CJN	penicillin-binding protein
GKS42_RS09840	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
GKS42_RS09850	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
GKS42_RS09855	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
GKS42_RS09865	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
GKS42_RS09870	ENOG4105DFU	Cell wall formation (By similarity)
GKS42_RS09880	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
GKS42_RS09885	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
GKS42_RS09890	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
GKS42_RS09900	ENOG4105XWG	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (By similarity)
GKS42_RS09915	ENOG4108HPG	-acetyltransferase
GKS42_RS09920	ENOG4108Z4X	TRANSCRIPTIONal
GKS42_RS09955	ENOG4105C0B	DNA polymerase III (alpha subunit)
GKS42_RS09975	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
GKS42_RS09990	ENOG4105C9U	ATP-dependent DNA helicase RecQ
GKS42_RS10015	ENOG4105CIH	Imidazole acetol-phosphate transaminase
GKS42_RS10020	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
GKS42_RS10030	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
GKS42_RS10035	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
GKS42_RS10045	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
GKS42_RS10050	ENOG4108BNZ	Ribosomal protein L35
GKS42_RS10055	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
GKS42_RS10060	ENOG4105C2N	RNA methyltransferase TrmH family group 3
GKS42_RS10105	ENOG4107104	thymidine kinase
GKS42_RS10150	ENOG4108Z0R	Transferase
GKS42_RS10165	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
GKS42_RS10170	ENOG4108MGF	sugar kinase
GKS42_RS10175	ENOG4107T5V	SNARE associated Golgi
GKS42_RS10195	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
GKS42_RS10200	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
GKS42_RS10220	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
GKS42_RS10250	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
GKS42_RS10275	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
GKS42_RS10280	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
GKS42_RS10285	ENOG4105CAS	nag kinase
GKS42_RS10290	ENOG4105C8Y	Acetylornithine aminotransferase
GKS42_RS10300	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
GKS42_RS10305	ENOG4105CDH	Citrulline--aspartate ligase
GKS42_RS10310	ENOG4105CH7	arginosuccinase
GKS42_RS10315	ENOG4105CAT	Cytidine monophosphate kinase
GKS42_RS10320	ENOG4108VX5	3-methyladenine DNA glycosylase
GKS42_RS10325	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
GKS42_RS10350	ENOG4105DSU	hydrolase
GKS42_RS10365	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
GKS42_RS10370	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
GKS42_RS10395	ENOG4105E2K	Glycosyl transferase (Group 1
GKS42_RS10400	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
GKS42_RS10405	ENOG4108YZ4	nudix hydrolase
GKS42_RS10435	ENOG4105JRK	feS assembly protein SufD
GKS42_RS10445	ENOG4105C3K	feS assembly ATPase SufC
GKS42_RS10455	ENOG4107YH3	SUF system FeS assembly protein, NifU family
GKS42_RS10460	ENOG4105VG1	fes assembly suf system protein
GKS42_RS10475	ENOG4105C5H	ABC transporter
GKS42_RS10480	ENOG4106NZI	LysR family Transcriptional regulator
GKS42_RS10485	ENOG4105UVJ	5-dehydro-4-deoxyglucarate dehydratase
GKS42_RS10510	ENOG4105CHR	reductase
GKS42_RS10525	ENOG4105EAC	phosphoserine phosphatase
GKS42_RS10535	ENOG4107QPH	glycogen) synthase
GKS42_RS10545	ENOG4105DKW	ABC transporter
GKS42_RS10570	ENOG4105BZF	Glycosyl transferase (Group 1
GKS42_RS10590	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GKS42_RS10600	ENOG4105HFS	5'-3' exonuclease
GKS42_RS10605	ENOG4105C3R	Methionine synthase
GKS42_RS10610	ENOG4105ETE	Transcriptional regulator (LacI family
GKS42_RS10650	ENOG4108V1U	phospholipid-binding protein
GKS42_RS10670	ENOG4105PEC	Iron-enterobactin transporter periplasmic binding protein
GKS42_RS10675	ENOG4105DQ5	transport system permease protein
GKS42_RS10680	ENOG4105TVJ	transport system, permease
GKS42_RS10685	ENOG4105E0A	ABC, transporter
GKS42_RS10705	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
GKS42_RS10710	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
GKS42_RS10720	ENOG4105C0B	DNA polymerase III (alpha subunit)
GKS42_RS10745	ENOG4105DDN	Pentapeptide repeat-containing protein
GKS42_RS10755	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
GKS42_RS10765	ENOG4105DSB	aldose 1-epimerase
GKS42_RS10770	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
GKS42_RS10800	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
GKS42_RS10805	ENOG4105DGW	oligopeptidase A
GKS42_RS10810	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
GKS42_RS10825	ENOG4105CPC	Aldo Keto reductase
GKS42_RS10830	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
GKS42_RS10835	ENOG4105C8N	cysteinyl-tRNA synthetase
GKS42_RS10845	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
GKS42_RS10860	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
GKS42_RS10865	ENOG4105E5F	proteasome
GKS42_RS10875	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
GKS42_RS10880	ENOG4105F7N	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
GKS42_RS10885	ENOG4105DVV	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine (By similarity)
GKS42_RS10895	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
GKS42_RS10905	ENOG4105BZ1	(ABC) transporter
GKS42_RS10910	ENOG4105BZ1	(ABC) transporter
GKS42_RS10915	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
GKS42_RS10945	ENOG4105DK0	Indole-3-glycerol phosphate synthase
GKS42_RS10950	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
GKS42_RS10955	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
GKS42_RS10960	ENOG4107TBN	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
GKS42_RS10965	ENOG4105CBC	glutamate synthase
GKS42_RS11090	ENOG4108W9H	Tetr family transcriptional regulator
GKS42_RS11095	ENOG4107S9B	Shikimate dehydrogenase
GKS42_RS11100	ENOG4107258	Transcriptional regulator
GKS42_RS11105	ENOG4107HP6	Transcriptional regulator
GKS42_RS11110	ENOG4105GQU	Trap dicarboxylate transporter, dctp subunit
GKS42_RS11115	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
GKS42_RS11125	ENOG4105C0A	alcohol dehydrogenase
GKS42_RS11130	ENOG4105BZN	citrate synthase
GKS42_RS11135	ENOG4105C7K	acetolactate synthase
GKS42_RS11160	ENOG4108TZA	Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules (By similarity)
GKS42_RS11180	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
GKS42_RS11185	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
GKS42_RS11190	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
GKS42_RS11205	ENOG4105Y7M	Transcriptional regulator, TetR family
GKS42_RS11210	ENOG4108Z9K	Osmotically inducible protein
GKS42_RS11220	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
GKS42_RS11235	ENOG4105QEK	Transcriptional regulator
GKS42_RS11240	ENOG4108SU4	UPF0309 protein
GKS42_RS11260	ENOG4106PVI	ATP-dependent carboxylate-amine ligase (By similarity)
GKS42_RS11290	ENOG4105BZP	glycoside hydrolase 15-related
GKS42_RS11300	ENOG4108YYH	Nadph-dependent fmn reductase
GKS42_RS11315	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
GKS42_RS11320	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
GKS42_RS11330	ENOG4105CIE	May be required for sporulation (By similarity)
GKS42_RS11340	ENOG4105BZA	Phosphoglycerate kinase
GKS42_RS11345	ENOG4105CP7	Triose-phosphate isomerase
GKS42_RS11395	ENOG4107TPY	serine threonine protein kinase
GKS42_RS11405	ENOG4107XU2	6-phosphogluconolactonase (EC 3.1.1.31)
GKS42_RS11420	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
GKS42_RS11430	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
GKS42_RS11485	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
GKS42_RS11490	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
GKS42_RS11510	ENOG4105CAT	Cytidine monophosphate kinase
GKS42_RS11525	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
GKS42_RS11535	ENOG4107RSM	transcriptional regulator
GKS42_RS11540	ENOG4105ETE	Transcriptional regulator (LacI family
GKS42_RS11550	ENOG4107W19	lmbE family
GKS42_RS11605	ENOG4105CXK	mandelate racemase muconate lactonizing
GKS42_RS11625	ENOG4105WBN	Transcriptional regulator (LacI family
GKS42_RS11650	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
GKS42_RS11655	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
GKS42_RS11665	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
GKS42_RS11675	ENOG4105DQV	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
GKS42_RS11705	ENOG4107U9T	Pfam:Ribonuclease_BN
GKS42_RS11745	ENOG4106PVI	ATP-dependent carboxylate-amine ligase (By similarity)
GKS42_RS11750	ENOG4108Z0Z	intracellular protease Pfpi family
GKS42_RS11790	ENOG4105D17	glycoside hydrolase, family 3 domain protein
GKS42_RS11795	ENOG4105EHZ	conserved protein UCP016719
GKS42_RS11805	ENOG4105D74	hydrolase
GKS42_RS11810	ENOG4108IG5	Transcriptional regulator
GKS42_RS11815	ENOG4105CHH	sulfate transporter
GKS42_RS11825	ENOG4108IG5	Transcriptional regulator
GKS42_RS11835	ENOG4105CV8	reductase
GKS42_RS11860	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
GKS42_RS11875	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
GKS42_RS11885	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
GKS42_RS11890	ENOG4108JE9	extracellular solute-binding protein family 1
GKS42_RS11895	ENOG4105HS6	binding-protein-dependent transport systems inner membrane Component
GKS42_RS11915	ENOG4105CXK	mandelate racemase muconate lactonizing
GKS42_RS11920	ENOG4108JQ1	Dehydrogenase
GKS42_RS11925	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
GKS42_RS11930	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
GKS42_RS11935	ENOG4105CHR	reductase
GKS42_RS11950	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
GKS42_RS11960	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
GKS42_RS11965	ENOG4107QM2	Aldo Keto reductase
GKS42_RS11980	ENOG4105C57	major facilitator superfamily
GKS42_RS11990	ENOG4105CIR	epoxide hydrolase
GKS42_RS12000	ENOG4107SI7	Substrate-binding region of abc-type glycine betaine transport system
GKS42_RS12005	ENOG4105E90	ABC transporter
GKS42_RS12010	ENOG4105E90	ABC transporter
GKS42_RS12015	ENOG4108IJ8	ABC transporter
GKS42_RS12040	ENOG4105CPC	Aldo Keto reductase
GKS42_RS12050	ENOG4105W2C	Glycosyl transferase
GKS42_RS12065	ENOG4105CZM	Major Facilitator
GKS42_RS12090	ENOG4105WH1	Two component transcriptional regulator luxr family
GKS42_RS12095	ENOG4105BZU	Histidine kinase
GKS42_RS12135	ENOG4108IUX	(ABC) transporter
GKS42_RS12140	ENOG4105WH1	Two component transcriptional regulator luxr family
GKS42_RS12145	ENOG4105BZU	Histidine kinase
GKS42_RS12185	ENOG4105WKW	Pfam:DUF1458
GKS42_RS12210	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
GKS42_RS12220	ENOG4105C26	Dehydrogenase
GKS42_RS12230	ENOG4105DH8	myo-inositol catabolism
GKS42_RS12240	ENOG4105EDK	PfkB domain protein
GKS42_RS12255	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
GKS42_RS12260	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
GKS42_RS12325	ENOG4105CMD	Transcriptional regulator, GntR family
GKS42_RS12350	ENOG4108JE9	extracellular solute-binding protein family 1
GKS42_RS12355	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
GKS42_RS12370	ENOG4105ETE	Transcriptional regulator (LacI family
GKS42_RS12375	ENOG4105F38	ABC transporter, permease
GKS42_RS12385	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GKS42_RS12395	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
GKS42_RS12415	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
GKS42_RS12455	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
GKS42_RS12465	ENOG4105F8D	glycoside hydrolase family 4
GKS42_RS12470	ENOG4108HYG	acetyltransferase
GKS42_RS12530	ENOG4105WWK	YheO domain protein
GKS42_RS12535	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
GKS42_RS12540	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GKS42_RS12545	ENOG4105CI2	imidazolone-5-propionate hydrolase
GKS42_RS12575	ENOG4105DRS	transport system, permease
GKS42_RS12595	ENOG4105FKQ	transcriptional regulator
GKS42_RS12625	ENOG4105DQ5	transport system permease protein
GKS42_RS12630	ENOG4105TVJ	transport system, permease
GKS42_RS12635	ENOG4105E0A	ABC, transporter
GKS42_RS12655	ENOG41088YA	Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives (By similarity)
GKS42_RS12670	ENOG4105NPE	arsR family transcriptional regulator
GKS42_RS12700	ENOG4108KPJ	rna polymerase sigma factor
GKS42_RS12725	ENOG4107SFS	Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA (By similarity)
GKS42_RS12740	ENOG4105CQ7	ATP-dependent helicase
GKS42_RS12775	ENOG4105EQP	Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (By similarity)
GKS42_RS12790	ENOG4108UKJ	Cdp-alcohol phosphatidyltransferase
GKS42_RS12830	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
GKS42_RS12840	ENOG4105E98	transcriptional regulator DeoR family
GKS42_RS12860	ENOG4105D2N	Aldolase
GKS42_RS12865	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
GKS42_RS12915	ENOG4105DMQ	Methyltransferase
GKS42_RS12930	ENOG4105RHY	Pfam:UPF0157
GKS42_RS12940	ENOG4108U3T	pfkb domain protein
GKS42_RS12960	ENOG41090KQ	Glyoxalase Bleomycin resistance protein (Dioxygenase
GKS42_RS12980	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
GKS42_RS13000	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
GKS42_RS13015	ENOG4105CPC	Aldo Keto reductase
GKS42_RS13025	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
GKS42_RS13045	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
GKS42_RS13050	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
GKS42_RS13065	ENOG4108FFZ	Transcriptional regulator
GKS42_RS13090	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
GKS42_RS13095	ENOG4105M0N	phosphoribosyl-ATP pyrophosphatase
GKS42_RS13100	ENOG4107XKF	NMT1 THI5 Like Domain Protein
GKS42_RS13105	ENOG4108I05	Binding-protein-dependent transport systems, inner membrane component
GKS42_RS13110	ENOG4105DJV	ribulose-phosphate 3-epimerase
GKS42_RS13120	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
GKS42_RS13130	ENOG4107RSZ	Primosomal protein n'
GKS42_RS13135	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
GKS42_RS13145	ENOG4105MTQ	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
GKS42_RS13150	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
GKS42_RS13160	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
GKS42_RS13165	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
GKS42_RS13170	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
GKS42_RS13175	ENOG4105CD3	dihydroorotase
GKS42_RS13180	ENOG4105CXT	aspartate transcarbamylase
GKS42_RS13185	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
GKS42_RS13190	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
GKS42_RS13205	ENOG410803B	Involved in the transcription termination process (By similarity)
GKS42_RS13210	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
GKS42_RS13225	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
GKS42_RS13230	ENOG4105D49	3-dehydroquinate synthase
GKS42_RS13235	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
GKS42_RS13240	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
GKS42_RS13250	ENOG4105E2X	shikimate dehydrogenase
GKS42_RS13260	ENOG41080G3	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
GKS42_RS13265	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
GKS42_RS13280	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
GKS42_RS13295	ENOG4107R13	MMPL domain protein
GKS42_RS13305	ENOG4105C9M	aspartyl-trna synthetase
GKS42_RS13310	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
GKS42_RS13325	ENOG4105CUT	histidyl-tRNA synthetase
GKS42_RS13335	ENOG4105C99	atpase involved in dna repair
GKS42_RS13340	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
GKS42_RS13345	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
GKS42_RS13350	ENOG4107RTU	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GKS42_RS13355	ENOG4107RSV	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GKS42_RS13365	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
GKS42_RS13370	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
GKS42_RS13375	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
GKS42_RS13380	ENOG4105CDY	transcriptional regulatory protein
GKS42_RS13385	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
GKS42_RS13390	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
GKS42_RS13395	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
GKS42_RS13410	ENOG4105E2K	Glycosyl transferase (Group 1
GKS42_RS13415	ENOG4107YQ3	lipid a biosynthesis lauroyl acyltransferase
GKS42_RS13430	ENOG4105C22	threonyL-tRNA synthetase
GKS42_RS13490	ENOG4108IUE	nitrate reductase beta subunit
GKS42_RS13515	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
GKS42_RS13520	ENOG4107VZS	Nicotinamide-nucleotide adenylyltransferase
GKS42_RS13595	ENOG4105CM4	permease protein
GKS42_RS13600	ENOG4108IPW	abc transporter atp-binding protein
GKS42_RS13645	ENOG4105CHU	acetyl-coa acetyltransferase
GKS42_RS13650	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
GKS42_RS13655	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
GKS42_RS13660	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
GKS42_RS13675	ENOG4107P2S	Transcriptional regulator
GKS42_RS13690	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
GKS42_RS13700	ENOG4105CEY	Amp-dependent synthetase and ligase
GKS42_RS13720	ENOG4107QM5	aconitate hydratase
GKS42_RS13730	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
GKS42_RS13735	ENOG4105C0X	amino acid
GKS42_RS13745	ENOG4107VEG	TrkA-N domain protein
GKS42_RS13770	ENOG4107ZFB	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
GKS42_RS13790	ENOG4107W53	thymidine kinase
GKS42_RS13810	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GKS42_RS13830	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GKS42_RS13860	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GKS42_RS13865	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
GKS42_RS13870	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
GKS42_RS13875	ENOG4105SHT	UspA domain-containing protein
GKS42_RS13900	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
GKS42_RS13910	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
GKS42_RS13915	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
GKS42_RS13920	ENOG4107RJF	diphosphate--fructose-6-phosphate 1-phosphotransferase (EC 2.7.1.90)
GKS42_RS13935	ENOG4108IQE	Amp-dependent synthetase and ligase
GKS42_RS13950	ENOG4108I0Q	anthranilate phosphoribosyltransferase
GKS42_RS13960	ENOG4105CCU	oxidase (Subunit III)
GKS42_RS13965	ENOG4107UDY	cytochrome C
GKS42_RS13970	ENOG4107EUI	c reductase, iron-sulfur
GKS42_RS13975	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
GKS42_RS13990	ENOG4105BZ9	Cytochrome C oxidase, subunit I
GKS42_RS13995	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
GKS42_RS14025	ENOG4105CPC	Aldo Keto reductase
GKS42_RS14030	ENOG4108DNI	pyridine nucleotide-disulfide oxidoreductase
GKS42_RS14035	ENOG4108KPJ	rna polymerase sigma factor
GKS42_RS14050	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
GKS42_RS14065	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
GKS42_RS14080	ENOG4105ECP	epimerase
GKS42_RS14085	ENOG4105CEP	NADH dehydrogenase
GKS42_RS14090	ENOG4107TPY	serine threonine protein kinase
GKS42_RS14125	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
GKS42_RS14135	ENOG4105ETE	Transcriptional regulator (LacI family
GKS42_RS14145	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
GKS42_RS14155	ENOG4105DRS	transport system, permease
GKS42_RS14175	ENOG410633P	Hydantoin racemase
GKS42_RS14180	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
GKS42_RS14185	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
GKS42_RS14195	ENOG4105CEP	NADH dehydrogenase
GKS42_RS14200	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
GKS42_RS14210	ENOG4105C5F	glutamine synthetase
GKS42_RS14220	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
GKS42_RS14225	ENOG4108UW5	maltose o-acetyltransferase
GKS42_RS14230	ENOG4105C5Q	Transcriptional regulator
GKS42_RS14235	ENOG4108FN7	Aldo keto reductase
GKS42_RS14240	ENOG4107QM2	Aldo Keto reductase
GKS42_RS14245	ENOG4105CPC	Aldo Keto reductase
GKS42_RS14290	ENOG4105WH1	Two component transcriptional regulator luxr family
GKS42_RS14300	ENOG4105BZU	Histidine kinase
GKS42_RS14315	ENOG4105WH1	Two component transcriptional regulator luxr family
GKS42_RS14320	ENOG4108JQ6	ABC transporter
GKS42_RS14325	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GKS42_RS14335	ENOG4105DEF	Extracellular solute-binding protein, family 5
GKS42_RS14350	ENOG4105XEA	Tetr family transcriptional regulator
GKS42_RS14375	ENOG4108MUZ	hydrolase
GKS42_RS14415	ENOG4105ETE	Transcriptional regulator (LacI family
GKS42_RS14425	ENOG4105C1G	acyl-Coa dehydrogenase
GKS42_RS14445	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
GKS42_RS14455	ENOG4105WEM	extracellular solute-binding protein
GKS42_RS14460	ENOG4107R0K	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity)
GKS42_RS14475	ENOG4105IIU	Aminopeptidase
GKS42_RS14485	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
GKS42_RS14490	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
GKS42_RS14510	ENOG410769Z	extracellular solute-binding protein family 1
GKS42_RS14515	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
GKS42_RS14540	ENOG41061ZR	Transcriptional regulator
GKS42_RS14595	ENOG4105EQX	glucarate dehydratase
GKS42_RS14600	ENOG4105JSC	dimethylmenaquinone methyltransferase
GKS42_RS14605	ENOG4105CHR	reductase
GKS42_RS14615	ENOG4105T16	Transcriptional regulator (AraC family)
GKS42_RS14625	ENOG4108KFM	Xylose Isomerase Domain-Containing protein
GKS42_RS14635	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
GKS42_RS14640	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
GKS42_RS14645	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
GKS42_RS14650	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
GKS42_RS14655	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
GKS42_RS14660	ENOG4107SET	aldo keto reductase
GKS42_RS14670	ENOG4105C9F	isomerase
GKS42_RS14675	ENOG4105DET	Rhamnulokinase
GKS42_RS14685	ENOG4105ETE	Transcriptional regulator (LacI family
GKS42_RS14695	ENOG4105ETE	Transcriptional regulator (LacI family
GKS42_RS14700	ENOG4107QWR	cellulase (EC 3.2.1.4)
GKS42_RS14725	ENOG4105DEF	Extracellular solute-binding protein, family 5
GKS42_RS14730	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GKS42_RS14735	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GKS42_RS14740	ENOG4108JQ6	ABC transporter
GKS42_RS14750	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
GKS42_RS14775	ENOG4105QNJ	serralysin (EC 3.4.24.40)
GKS42_RS14790	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
GKS42_RS14820	ENOG4108JQ6	ABC transporter
GKS42_RS14880	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
GKS42_RS14885	ENOG4105C5F	glutamine synthetase
GKS42_RS14890	ENOG4105C4K	Nad synthetase
GKS42_RS14895	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
GKS42_RS14910	ENOG4105FDF	Could be involved in DNA repair (By similarity)
GKS42_RS14920	ENOG4105E2R	ROK family
GKS42_RS14930	ENOG4105DRS	transport system, permease
GKS42_RS14940	ENOG4105CJQ	hydrolase, family 31
GKS42_RS14960	ENOG4108MR6	WD40-like Beta Propeller Repeat
GKS42_RS14970	ENOG4105KME	endoribonuclease L-psp
GKS42_RS15000	ENOG4108RU2	n-acetylmuramoyl-l-alanine amidase
GKS42_RS15030	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
GKS42_RS15035	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
GKS42_RS15040	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
GKS42_RS15075	ENOG4105E0Y	RtcB Protein
GKS42_RS15120	ENOG4106PMH	Extracellular solute-binding protein family 3
GKS42_RS15125	ENOG4105DRP	amino acid AbC transporter
GKS42_RS15140	ENOG4107XFJ	UPF0246 protein
GKS42_RS15170	ENOG4105M4E	phosphohistidine phosphatase, SixA
GKS42_RS15185	ENOG4105DRP	amino acid AbC transporter
GKS42_RS15190	ENOG4105DRP	amino acid AbC transporter
GKS42_RS15245	ENOG4105BZU	Histidine kinase
GKS42_RS15250	ENOG4105WH1	Two component transcriptional regulator luxr family
GKS42_RS15290	ENOG4105GRZ	Ycii-related protein
GKS42_RS15295	ENOG4105CHP	RNA polymerase
GKS42_RS15305	ENOG4107RBJ	symporter
GKS42_RS15320	ENOG4107S1N	anthranilate phosphoribosyltransferase
GKS42_RS15360	ENOG4105D3R	alkyl hydroperoxide reductase
GKS42_RS15370	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
GKS42_RS15400	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
GKS42_RS15405	ENOG41082KT	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
GKS42_RS15410	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
GKS42_RS15420	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
GKS42_RS15430	ENOG4105D5P	Methylmalonyl-coA mutase
GKS42_RS15460	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
GKS42_RS15465	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
GKS42_RS15470	ENOG4105CG3	alpha amylase, catalytic region
GKS42_RS15480	ENOG4105EG2	ABC transporter, permease
GKS42_RS15485	ENOG4105D56	permease protein
GKS42_RS15490	ENOG4107FKK	extracellular solute-binding protein family 1
GKS42_RS15515	ENOG4105DRS	transport system, permease
GKS42_RS15530	ENOG4105ETE	Transcriptional regulator (LacI family
GKS42_RS15540	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
GKS42_RS15555	ENOG4105DIK	(ABC) transporter
GKS42_RS15575	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
GKS42_RS15580	ENOG4106DBE	Involved in DNA repair and RecF pathway recombination (By similarity)
GKS42_RS15600	ENOG4108KPJ	rna polymerase sigma factor
GKS42_RS15625	ENOG4107QXN	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
GKS42_RS15650	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
GKS42_RS15685	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
GKS42_RS15695	ENOG4107VNR	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
GKS42_RS15730	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
GKS42_RS15735	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
GKS42_RS15755	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
GKS42_RS15810	ENOG4105CEY	Amp-dependent synthetase and ligase
GKS42_RS15820	ENOG4105C32	Amino acid ABC transporter (Permease)
GKS42_RS15825	ENOG4108IV0	ABC, transporter
GKS42_RS15830	ENOG4105C0Z	ABC transporter
GKS42_RS15840	ENOG4105CHU	acetyl-coa acetyltransferase
GKS42_RS15850	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
GKS42_RS15960	ENOG4105D7A	ATP-binding protein
GKS42_RS15965	ENOG4105DJB	Major Facilitator Superfamily
GKS42_RS15975	ENOG4105C8T	Leucyl-tRNA synthetase
GKS42_RS15980	ENOG4105ETE	Transcriptional regulator (LacI family
GKS42_RS15990	ENOG4105CBG	Sulfatase
GKS42_RS15995	ENOG4108UZX	fmn reductase
GKS42_RS16010	ENOG4105CMG	Carbohydrate kinase
GKS42_RS16015	ENOG4105DEI	Mannitol dehydrogenase
GKS42_RS16020	ENOG4105D2H	Uronic isomerase
GKS42_RS16025	ENOG4105ETE	Transcriptional regulator (LacI family
GKS42_RS16040	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
GKS42_RS16045	ENOG4105DVM	PP-loop domain protein
GKS42_RS16050	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
GKS42_RS16055	ENOG4105C37	(CBS) domain
GKS42_RS16065	ENOG4107R5H	iron (metal) dependent repressor, dtxr family
GKS42_RS16100	ENOG4105DRS	transport system, permease
GKS42_RS16125	ENOG4108RVA	ribokinase
GKS42_RS16130	ENOG4105C2X	Arabinose 5-phosphate isomerase
GKS42_RS16140	ENOG4105ETE	Transcriptional regulator (LacI family
GKS42_RS16160	ENOG4105BZ1	(ABC) transporter
GKS42_RS16165	ENOG4105BZ1	(ABC) transporter
GKS42_RS16170	ENOG4105FDF	Could be involved in DNA repair (By similarity)
GKS42_RS16175	ENOG4105NX3	Membrane
GKS42_RS16195	ENOG4105DUM	transcriptional regulator, lysR family
GKS42_RS16220	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
GKS42_RS16230	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
GKS42_RS16245	ENOG4106448	streptomycin biosynthesis protein strI
GKS42_RS16260	ENOG4105CEU	Arginine dihydrolase
GKS42_RS16315	ENOG4105CSV	Glutaminase
GKS42_RS16330	ENOG4105KVH	Transcriptional regulator
GKS42_RS16365	ENOG4105CVJ	phosphoglycerate mutase
GKS42_RS16380	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
GKS42_RS16385	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
GKS42_RS16400	ENOG4108UZX	fmn reductase
GKS42_RS16425	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
GKS42_RS16430	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GKS42_RS16435	ENOG4105K46	50S ribosomal protein l27
GKS42_RS16440	ENOG410826X	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
GKS42_RS16445	ENOG4105EC3	peptidase S51, dipeptidase E
GKS42_RS16455	ENOG4105C03	ribonuclease
GKS42_RS16460	ENOG4105C4M	(Ubiquinol oxidase) subunit I
GKS42_RS16465	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
GKS42_RS16470	ENOG4108JJ9	ABC, transporter
GKS42_RS16475	ENOG4108JJ8	(ABC) transporter
GKS42_RS16485	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
GKS42_RS16500	ENOG41060NJ	transcriptional regulator
GKS42_RS16505	ENOG4108UHU	Aldolase
GKS42_RS16510	ENOG4105D7K	pfkb domain protein
GKS42_RS16525	ENOG4107S1E	Beta-lactamase
GKS42_RS16540	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
GKS42_RS16545	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
GKS42_RS16560	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
GKS42_RS16565	ENOG4105CTX	dehydratase
GKS42_RS16605	ENOG4107V6K	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
GKS42_RS16610	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
GKS42_RS16615	ENOG4106H78	methyltransferase
GKS42_RS16625	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
GKS42_RS16630	ENOG4105CB5	ATP-dependent DNA helicase recG
GKS42_RS16635	ENOG4105VB9	50S ribosomal protein l28
GKS42_RS16650	ENOG4105NFX	aminoglycoside hydroxyurea antibiotic resistance kinase
GKS42_RS16660	ENOG4107RWR	Sodium hydrogen exchanger
GKS42_RS16670	ENOG4105CHR	reductase
GKS42_RS16705	ENOG41067QW	Transcriptional regulator
GKS42_RS16710	ENOG4105CPF	Cell wall formation (By similarity)
GKS42_RS16735	ENOG4108KX4	response regulator
GKS42_RS16740	ENOG4105BZU	Histidine kinase
GKS42_RS16750	ENOG4108M15	ABC transporter
GKS42_RS16755	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
GKS42_RS16770	ENOG4105DA5	(ABC) transporter
GKS42_RS16780	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
GKS42_RS16785	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
GKS42_RS16790	ENOG41069M3	Transcriptional regulator
GKS42_RS16825	ENOG4105BZU	Histidine kinase
GKS42_RS16830	ENOG4105DA5	(ABC) transporter
GKS42_RS16840	ENOG4105EMU	Dehydrogenase
GKS42_RS16855	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
GKS42_RS16865	ENOG4105DXB	Major Facilitator superfamily
GKS42_RS16895	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
GKS42_RS16905	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
GKS42_RS16930	ENOG4108R3E	Dna-3-methyladenine glycosylase i
GKS42_RS16955	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GKS42_RS16980	ENOG4107RYT	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair (By similarity)
GKS42_RS16985	ENOG4108Z4X	TRANSCRIPTIONal
GKS42_RS17035	ENOG4108KGH	TRANSCRIPTIONal
GKS42_RS17055	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
GKS42_RS17060	ENOG4105D52	delta-aminolevulinic acid dehydratase
GKS42_RS17070	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
GKS42_RS17075	ENOG4107QME	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
GKS42_RS17090	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
GKS42_RS17105	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
GKS42_RS17120	ENOG41060NJ	transcriptional regulator
GKS42_RS17130	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
GKS42_RS17160	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
GKS42_RS17165	ENOG4105C31	Tryptophanyl-tRNA synthetase
GKS42_RS17185	ENOG4108Z66	YbaK ebsC protein
GKS42_RS17205	ENOG4105DFA	alanine racemase domain protein
GKS42_RS17210	ENOG41080RH	Thioredoxin
GKS42_RS17230	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
GKS42_RS17260	ENOG4105CM2	brancheD-chain amino acid aminotransferase
GKS42_RS17265	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
GKS42_RS17285	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
GKS42_RS17290	ENOG4108ZP8	Acetolactate synthase small subunit
GKS42_RS17300	ENOG4105KZX	Pterin carbinolamine dehydratase
GKS42_RS17305	ENOG4105C01	Dihydroxy-acid dehydratase
GKS42_RS17350	ENOG4105BZW	Glycerate kinase
GKS42_RS17355	ENOG41060W2	glyoxylate carboligase
GKS42_RS17360	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
GKS42_RS17365	ENOG4107TFQ	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
GKS42_RS17385	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
GKS42_RS17415	ENOG41069M3	Transcriptional regulator
GKS42_RS17420	ENOG4105C2W	permease
GKS42_RS17435	ENOG41084YZ	Hydrolase
GKS42_RS17450	ENOG4107R9S	Malate synthase
GKS42_RS17470	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
GKS42_RS17480	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
GKS42_RS17485	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
GKS42_RS17490	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
GKS42_RS17505	ENOG4108CIP	transcriptional regulator
GKS42_RS17510	ENOG4107HQ7	repeat protein
GKS42_RS17570	ENOG4105CHH	sulfate transporter
GKS42_RS17580	ENOG41061ZR	Transcriptional regulator
GKS42_RS17615	ENOG4107R7A	Allophanate hydrolase subunit 2
GKS42_RS17625	ENOG4105E7W	lamb ycsf family protein
GKS42_RS17685	ENOG41061ZR	Transcriptional regulator
GKS42_RS17685	ENOG41061ZR	Transcriptional regulator
GKS42_RS17700	ENOG4105CBG	Sulfatase
GKS42_RS17720	ENOG4107RTG	Major Facilitator superfamily
GKS42_RS17730	ENOG4105BZ1	(ABC) transporter
GKS42_RS17755	ENOG4105CIB	oxidoreductase Domain protein
GKS42_RS17760	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
GKS42_RS17765	ENOG4105CNN	ABC, transporter
GKS42_RS17775	ENOG4105E2R	ROK family
GKS42_RS17790	ENOG4105CFC	Transporter
GKS42_RS17795	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
GKS42_RS17805	ENOG4107QWE	)-transporter
GKS42_RS17825	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
GKS42_RS17855	ENOG4107QRS	glycosyltransferase group 2 family protein
GKS42_RS17880	ENOG4105EWK	phytoene
GKS42_RS17895	ENOG4108ZEY	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
GKS42_RS17915	ENOG4105CGD	Nad-dependent epimerase dehydratase
GKS42_RS17955	ENOG4105QPS	Monooxygenase
GKS42_RS17975	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
GKS42_RS18000	ENOG4105H3G	oxidoreductase
GKS42_RS18020	ENOG4108KTG	Membrane protein, drug metabolite transporter
GKS42_RS18030	ENOG4105KVH	Transcriptional regulator
GKS42_RS18035	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
GKS42_RS18050	ENOG4105C10	Electron transfer flavoprotein
GKS42_RS18055	ENOG4105BZJ	Electron transfer flavoprotein
GKS42_RS18070	ENOG4105C31	Tryptophanyl-tRNA synthetase
GKS42_RS18085	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
GKS42_RS18095	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
GKS42_RS18105	ENOG4105K63	Thioredoxin
GKS42_RS18130	ENOG4107S9D	Alpha beta hydrolase
GKS42_RS18160	ENOG4105CJQ	hydrolase, family 31
GKS42_RS18175	ENOG4105ETE	Transcriptional regulator (LacI family
GKS42_RS18185	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
GKS42_RS18220	ENOG4107R4N	Cell wall formation (By similarity)
GKS42_RS18225	ENOG4105CE4	GlcNAc 6-P deacetylase
GKS42_RS18230	ENOG4105CYV	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures (By similarity)
GKS42_RS18240	ENOG410825K	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
GKS42_RS18245	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
GKS42_RS18250	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
GKS42_RS18255	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
GKS42_RS18260	ENOG4108T62	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GKS42_RS18265	ENOG4107Z0K	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
GKS42_RS18270	ENOG4105ZA1	atp synthase
GKS42_RS18275	ENOG4107UH5	it plays a direct role in the translocation of protons across the membrane (By similarity)
GKS42_RS18300	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
GKS42_RS18305	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
GKS42_RS18315	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
GKS42_RS18320	ENOG4107R5I	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
GKS42_RS18325	ENOG4105D6E	homoserine dehydrogenase
GKS42_RS18330	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
GKS42_RS18335	ENOG4105C75	arginyL-tRNA synthetase
GKS42_RS18350	ENOG4107WI4	Aldose-1-epimerase
GKS42_RS18355	ENOG4105E4C	Lytic transglycosylase catalytic
GKS42_RS18360	ENOG4107UAX	integral membrane protein
GKS42_RS18365	ENOG4105C37	(CBS) domain
GKS42_RS18370	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GKS42_RS18375	ENOG4105EB3	Histidine kinase
GKS42_RS18380	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
GKS42_RS18400	ENOG4105C8J	)-transporter
GKS42_RS18420	ENOG4105CK5	oxidoreductase
GKS42_RS18425	ENOG4105WMN	AntiSigma factor
GKS42_RS18430	ENOG4105EMN	RNA polymerase sigma factor
GKS42_RS18440	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
GKS42_RS18445	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
GKS42_RS18485	ENOG4105I82	acetyl xylan esterase
GKS42_RS18490	ENOG4105EQX	glucarate dehydratase
GKS42_RS18510	ENOG4108JE9	extracellular solute-binding protein family 1
GKS42_RS18525	ENOG4108FUF	Transcriptional regulator, IclR family
GKS42_RS18530	ENOG4107TK4	histidinol-phosphate phosphatase
GKS42_RS18545	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
GKS42_RS18565	ENOG4105D1F	ATP-binding protein
GKS42_RS18585	ENOG4107Y2X	deaminase
GKS42_RS18610	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
GKS42_RS18615	ENOG4105T0Z	Conserved Protein
GKS42_RS18620	ENOG4108S7Q	sigma 54 modulation protein ribosomal protein S30ea
GKS42_RS18625	ENOG4105MJ2	Competence protein
GKS42_RS18630	ENOG4105G3P	Lipoprotein lpqB
GKS42_RS18635	ENOG4105BZU	Histidine kinase
GKS42_RS18655	ENOG4108WQ6	secreted protein
GKS42_RS18660	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
GKS42_RS18670	ENOG4105DIA	mandelate racemase muconate lactonizing
GKS42_RS18675	ENOG4105JXH	GntR family transcriptional regulator
GKS42_RS18690	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
GKS42_RS18695	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
GKS42_RS18700	ENOG4107QPT	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
GKS42_RS18715	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
GKS42_RS18735	ENOG4105CKK	Glycosyl transferase, family 2
GKS42_RS18770	ENOG4105CTC	Lipopolysaccharide biosynthesis protein-like protein
GKS42_RS18785	ENOG4105EY8	ABC transporter
GKS42_RS18825	ENOG4105W49	UPF0434 protein
GKS42_RS18830	ENOG4107QKV	phosphomannomutase
GKS42_RS18855	ENOG4105K51	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
GKS42_RS18865	ENOG4105EIP	mannose-6-phosphate isomerase
GKS42_RS18870	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
GKS42_RS18880	ENOG4107QQG	Dehydrogenase
GKS42_RS18895	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
GKS42_RS18905	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
GKS42_RS18910	ENOG4105BZ1	(ABC) transporter
GKS42_RS18950	ENOG4108KGH	TRANSCRIPTIONal
GKS42_RS18955	ENOG4108KGH	TRANSCRIPTIONal
GKS42_RS18960	ENOG4108KGH	TRANSCRIPTIONal
GKS42_RS18965	ENOG4105K4P	CoA-binding domain protein
GKS42_RS18980	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
GKS42_RS18995	ENOG41065SU	Two-component system sensor kinase
GKS42_RS19000	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GKS42_RS19010	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
GKS42_RS19020	ENOG4107VMU	Membrane
GKS42_RS19025	ENOG4105D8K	carboxyl transferase
GKS42_RS19090	ENOG4107WR6	Maf-like protein
GKS42_RS19095	ENOG4108JIK	carboxylase
GKS42_RS19105	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
GKS42_RS19135	ENOG4108Z4U	Ferredoxin
GKS42_RS19160	ENOG4105CI3	gtp-binding protein typa
GKS42_RS19175	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GKS42_RS19190	ENOG4105E9K	Isocitrate dehydrogenase
GKS42_RS19220	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
GKS42_RS19245	ENOG4107TYG	Oxidoreductase domain-containing protein
GKS42_RS19280	ENOG4108J2P	Alpha beta hydrolase fold
GKS42_RS19295	ENOG4108JGH	Tetr family transcriptional regulator
GKS42_RS19310	ENOG4105WH1	Two component transcriptional regulator luxr family
GKS42_RS19315	ENOG4105BZU	Histidine kinase
GKS42_RS19320	ENOG41086D8	Transcriptional regulator
GKS42_RS19355	ENOG41068WN	
GKS42_RS19395	ENOG4105C3G	gtp-binding protein
GKS42_RS19425	ENOG4108IJG	ABC transporter substrate-binding protein
GKS42_RS19430	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
GKS42_RS19435	ENOG4105EVE	HAD-superfamily hydrolase subfamily IA variant 3
GKS42_RS19440	ENOG4105DKT	Transcriptional regulator
GKS42_RS19445	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
GKS42_RS19450	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
GKS42_RS19455	ENOG4105YX8	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
GKS42_RS19460	ENOG4105D7K	pfkb domain protein
GKS42_RS19490	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
GKS42_RS19495	ENOG4108IAB	Phoh family
GKS42_RS19500	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
GKS42_RS19510	ENOG4105CSR	polyphosphate kinase 2
GKS42_RS19525	ENOG4105T1M	mycothiol conjugate amidase mca
GKS42_RS19545	ENOG4107YD5	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
GKS42_RS19550	ENOG4105C7B	Threonine dehydratase
GKS42_RS19560	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
GKS42_RS19575	ENOG4105I82	acetyl xylan esterase
GKS42_RS19595	ENOG4105BZU	Histidine kinase
GKS42_RS19600	ENOG4105WH1	Two component transcriptional regulator luxr family
GKS42_RS19640	ENOG4105C7S	Dehydrogenase
GKS42_RS19645	ENOG4108JYK	Dehydrogenase
GKS42_RS19650	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
GKS42_RS19655	ENOG4105DRR	Transcriptional regulator, GntR family
GKS42_RS19665	ENOG4108IV0	ABC, transporter
GKS42_RS19670	ENOG4105C0Z	ABC transporter
GKS42_RS19680	ENOG4105C32	Amino acid ABC transporter (Permease)
GKS42_RS19705	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GKS42_RS19750	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
GKS42_RS19765	ENOG41081R7	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
GKS42_RS19785	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
GKS42_RS19790	ENOG4108IYU	L-aspartate oxidase
GKS42_RS19795	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
GKS42_RS19800	ENOG4105C3J	Cysteine desulfurase
GKS42_RS19825	ENOG4108KGH	TRANSCRIPTIONal
GKS42_RS19835	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
GKS42_RS19840	ENOG4107XT7	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
GKS42_RS19850	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
GKS42_RS19855	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
GKS42_RS19865	ENOG41067SE	Tetr family transcriptional regulator
GKS42_RS19870	ENOG4108IUX	(ABC) transporter
GKS42_RS19875	ENOG4105RHA	ABC transporter, permease
GKS42_RS19880	ENOG4108VHT	MarR family transcriptional regulator
GKS42_RS19885	ENOG4105C5H	ABC transporter
GKS42_RS19900	ENOG4107R13	MMPL domain protein
GKS42_RS19905	ENOG4107Z3H	Transcriptional regulator, TetR family
GKS42_RS19910	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
GKS42_RS19915	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
GKS42_RS19930	ENOG4105F8V	Hydrolase, tatD family
GKS42_RS19935	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
GKS42_RS19970	ENOG4105EUJ	GTP cyclohydrolase i
GKS42_RS19980	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
GKS42_RS19985	ENOG4105CHM	Aminotransferase
GKS42_RS19990	ENOG4108RWI	nicotinamidase
GKS42_RS19995	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
GKS42_RS20045	ENOG4105CV8	reductase
GKS42_RS20060	ENOG4105CIR	epoxide hydrolase
GKS42_RS20065	ENOG4105E2D	ec 3.2.1.52
GKS42_RS20075	ENOG4105ETE	Transcriptional regulator (LacI family
GKS42_RS20080	ENOG4105CHF	Glutathione S-transferase
GKS42_RS20090	ENOG4105RYD	Toxic component of a toxin-antitoxin (TA) module. A
GKS42_RS20125	ENOG4105EQK	-acetyltransferase
GKS42_RS20130	ENOG4105DUM	transcriptional regulator, lysR family
GKS42_RS20135	ENOG4105HMI	Membrane
GKS42_RS20145	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
GKS42_RS20155	ENOG4105CMR	udp-glucose 4-epimerase
GKS42_RS20160	ENOG4107W19	lmbE family
GKS42_RS20165	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
GKS42_RS20175	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
GKS42_RS20225	ENOG4105CKK	Glycosyl transferase, family 2
GKS42_RS20235	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
GKS42_RS20240	ENOG41076QQ	Glycosyl transferase, family 2
GKS42_RS20275	ENOG4105CMT	Dihydroxyacetone kinase
GKS42_RS20300	ENOG4108SKZ	Patatin-like phospholipase
GKS42_RS20320	ENOG4105D5U	fad dependent oxidoreductase
GKS42_RS20335	ENOG4105EFJ	Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity)
GKS42_RS20340	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GKS42_RS20360	ENOG4105C5Q	Transcriptional regulator
GKS42_RS20365	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
GKS42_RS20370	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
GKS42_RS20400	ENOG4105K6V	RNA polymerase
GKS42_RS20405	ENOG4105RNG	membrane
GKS42_RS20460	ENOG4106F60	Histidine kinase
GKS42_RS20465	ENOG4105F44	Two component transcriptional regulator, winged helix family
GKS42_RS20480	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
GKS42_RS20505	ENOG4107TXC	Transcriptional regulator
GKS42_RS20530	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
GKS42_RS20550	ENOG41080FJ	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
GKS42_RS20560	ENOG4105K78	MarR family Transcriptional regulator
GKS42_RS20565	ENOG4105WH1	Two component transcriptional regulator luxr family
GKS42_RS20570	ENOG4105BZU	Histidine kinase
GKS42_RS20580	ENOG4105CJ1	ABC, transporter
GKS42_RS20615	ENOG4105C8Y	Acetylornithine aminotransferase
GKS42_RS20640	ENOG4107R8H	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
GKS42_RS20645	ENOG4105CHR	reductase
GKS42_RS20655	ENOG4108JJB	ABC transporter
GKS42_RS20660	ENOG4105NSK	ABC superfamily ATP binding cassette transporter membrane protein
GKS42_RS20670	ENOG4107SFI	Major Facilitator superfamily
GKS42_RS20685	ENOG4105C7N	Xanthine uracil vitamin C permease
GKS42_RS20710	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
GKS42_RS20730	ENOG4105EIP	mannose-6-phosphate isomerase
GKS42_RS20740	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
GKS42_RS20770	ENOG4108I5G	Major Facilitator superfamily
GKS42_RS20790	ENOG4105VEQ	Cold shock protein
GKS42_RS20795	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
GKS42_RS20800	ENOG4105D3Q	Sugar transferase
GKS42_RS20820	ENOG4105JNK	Glycosyl transferase (Group 1
GKS42_RS20840	ENOG4107YJ4	chain length determinant protein
GKS42_RS20845	ENOG4107ZF2	Phosphatase
GKS42_RS20860	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
GKS42_RS20870	ENOG4105CPC	Aldo Keto reductase
GKS42_RS20915	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
GKS42_RS20960	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GKS42_RS20965	ENOG4105BZU	Histidine kinase
GKS42_RS20985	ENOG4105X1Q	TOBE domain protein
GKS42_RS21005	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
GKS42_RS21045	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
GKS42_RS21055	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
GKS42_RS21080	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
GKS42_RS21105	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
GKS42_RS21130	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
GKS42_RS21165	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
GKS42_RS21190	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
GKS42_RS21195	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
GKS42_RS21205	ENOG4105ETE	Transcriptional regulator (LacI family
GKS42_RS21215	ENOG4105C2N	RNA methyltransferase TrmH family group 3
GKS42_RS21220	ENOG4105C8N	cysteinyl-tRNA synthetase
GKS42_RS21225	ENOG4105ERH	Fumarylacetoacetate hydrolase
GKS42_RS21235	ENOG4105CXK	mandelate racemase muconate lactonizing
GKS42_RS21245	ENOG4105CXK	mandelate racemase muconate lactonizing
GKS42_RS21250	ENOG4105CYF	SMP-30 gluconolaconase LRE domain protein
GKS42_RS21260	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
GKS42_RS21270	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
GKS42_RS21275	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
GKS42_RS21300	ENOG4105BZ1	(ABC) transporter
GKS42_RS21320	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
GKS42_RS21325	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
GKS42_RS21330	ENOG4108VJ1	Transcriptional regulator (CarD family
GKS42_RS21345	ENOG4105BZU	Histidine kinase
GKS42_RS21355	ENOG4107RPC	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
GKS42_RS21370	ENOG4105CRK	lysyL-tRNA synthetase
GKS42_RS21375	ENOG4107QQT	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
GKS42_RS21405	ENOG4105EUJ	GTP cyclohydrolase i
GKS42_RS21410	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
GKS42_RS21415	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
GKS42_RS21420	ENOG4107RD1	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
GKS42_RS21435	ENOG4105F0N	pyrophosphate phospho-hydrolase
GKS42_RS21455	ENOG4105DWV	Homoserine O-trans-acetylase
GKS42_RS21475	ENOG4105CQB	FAD linked oxidase domain protein
GKS42_RS21495	ENOG4107PP3	Acetylornithine deacetylase
GKS42_RS21505	ENOG4105E5D	amino acid
GKS42_RS21570	ENOG4108WC5	Alpha Beta Hydrolase Fold protein
GKS42_RS21610	ENOG4105C6E	dna polymerase iii
GKS42_RS21615	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
GKS42_RS21635	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
GKS42_RS21640	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
GKS42_RS21675	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
GKS42_RS21695	ENOG41082W1	Cupin 2, conserved barrel domain protein
GKS42_RS21700	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
GKS42_RS21725	ENOG4105EMN	RNA polymerase sigma factor
GKS42_RS21745	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
GKS42_RS21750	ENOG4108RZE	Tetr family transcriptional regulator
GKS42_RS21755	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
GKS42_RS21770	ENOG4107W19	lmbE family
GKS42_RS21780	ENOG4107QJZ	Glycosyl transferase, family 2
GKS42_RS21785	ENOG4105C4K	Nad synthetase
GKS42_RS21795	ENOG4108IG5	Transcriptional regulator
GKS42_RS21850	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
GKS42_RS21885	ENOG4108JQC	penicillin-binding protein 1A
GKS42_RS21900	ENOG4105C2W	permease
GKS42_RS21905	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
GKS42_RS21910	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
GKS42_RS21920	ENOG4105ETE	Transcriptional regulator (LacI family
GKS42_RS21930	ENOG4105C3U	ABC transporter
GKS42_RS21935	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GKS42_RS21945	ENOG4105E43	Extracellular solute-binding protein, family 5
GKS42_RS21960	ENOG4105CR4	methylisocitrate lyase
GKS42_RS21990	ENOG4105CFH	Aspartokinase
GKS42_RS22000	ENOG4105DA5	(ABC) transporter
GKS42_RS22015	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
GKS42_RS22065	ENOG4108JJB	ABC transporter
GKS42_RS22085	ENOG4105CPQ	Dehydrogenase
GKS42_RS22115	ENOG41090K0	Transcriptional regulator, Crp Fnr family
GKS42_RS22175	ENOG4107QJE	Chromosome Partitioning Protein
GKS42_RS22230	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
GKS42_RS22275	ENOG4105JSC	dimethylmenaquinone methyltransferase
GKS42_RS22330	ENOG4105EGI	Transcriptional regulator
GKS42_RS22345	ENOG4105DET	Rhamnulokinase
GKS42_RS22355	ENOG4105C9F	isomerase
GKS42_RS22365	ENOG4105C01	Dihydroxy-acid dehydratase
GKS42_RS22370	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
GKS42_RS22375	ENOG410680H	amp-dependent synthetase and ligase
GKS42_RS22380	ENOG4105E2T	synthase III
GKS42_RS22385	ENOG4105CPQ	Dehydrogenase
GKS42_RS22410	ENOG4106KNT	transcriptional regulator
GKS42_RS22415	ENOG4107QK9	Beta-lactamase
GKS42_RS22420	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GKS42_RS22425	ENOG4105D17	glycoside hydrolase, family 3 domain protein
GKS42_RS22430	ENOG4108JQ7	(ABC) transporter
GKS42_RS22460	ENOG4105EHZ	conserved protein UCP016719
GKS42_RS22480	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
GKS42_RS22490	ENOG4105E0S	extracellular solute-binding protein family 1
GKS42_RS22510	ENOG4105ETE	Transcriptional regulator (LacI family
GKS42_RS22520	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
GKS42_RS22530	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
GKS42_RS22540	ENOG4105CPQ	Dehydrogenase
GKS42_RS22545	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
GKS42_RS22555	ENOG4105EF1	ribulokinase
GKS42_RS22560	ENOG4105ETE	Transcriptional regulator (LacI family
GKS42_RS22570	ENOG4105E0S	extracellular solute-binding protein family 1
GKS42_RS22580	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
GKS42_RS22585	ENOG4107TDE	lipolytic protein G-D-S-L family
GKS42_RS22590	ENOG4105EKC	
GKS42_RS22615	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
GKS42_RS22625	ENOG4105CPQ	Dehydrogenase
GKS42_RS22630	ENOG4105C1J	atp-dependent rna helicase
GKS42_RS22665	ENOG4108UVJ	appr-1-p processing domain protein
GKS42_RS22675	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
GKS42_RS22695	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
GKS42_RS22700	ENOG4108X6U	May play a role in the intracellular transport of hydrophobic ligands
GKS42_RS22710	ENOG4107NHD	transcriptional regulator
GKS42_RS22720	ENOG4105CJ3	phosphate transporter
GKS42_RS22735	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
GKS42_RS22760	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
GKS42_RS22765	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
GKS42_RS22805	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
GKS42_RS22820	ENOG4105D17	glycoside hydrolase, family 3 domain protein
GKS42_RS22865	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
GKS42_RS22870	ENOG4105Y3U	Transglycosylase-associated protein
GKS42_RS22885	ENOG4105E0X	reductase
GKS42_RS22895	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
GKS42_RS22925	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GKS42_RS22950	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
GKS42_RS22960	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
GKS42_RS22980	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
GKS42_RS22990	ENOG4105ETE	Transcriptional regulator (LacI family
GKS42_RS22995	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
GKS42_RS23005	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
GKS42_RS23025	ENOG4105D7N	magnesium and cobalt transport protein CorA
GKS42_RS23040	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
GKS42_RS23055	ENOG4105CIR	epoxide hydrolase
GKS42_RS23065	ENOG4106N3A	copper homeostasis protein cutc
GKS42_RS23070	ENOG4105D82	Glutamate dehydrogenase
GKS42_RS23090	ENOG4105DEN	Luciferase family
GKS42_RS23100	ENOG4108J59	Extracellular solute-binding protein, family 5
GKS42_RS23105	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
GKS42_RS23110	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
GKS42_RS23120	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GKS42_RS23125	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GKS42_RS23130	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
GKS42_RS23140	ENOG4105D64	Mechanosensitive ion channel
GKS42_RS23145	ENOG4105C8Q	Methyl-accepting chemotaxis
GKS42_RS23180	ENOG4107RT5	aminobenzoyl-glutamate utilization protein B
GKS42_RS23220	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
GKS42_RS23230	ENOG4105DSU	hydrolase
GKS42_RS23250	ENOG4107JBM	CrcB-like protein
GKS42_RS23255	ENOG4108680	CrcB-like protein
GKS42_RS23285	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GKS42_RS23300	ENOG4108JQ7	(ABC) transporter
GKS42_RS23310	ENOG4105JSC	dimethylmenaquinone methyltransferase
GKS42_RS23315	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
GKS42_RS23400	ENOG4107SET	aldo keto reductase
GKS42_RS23430	ENOG4105CHU	acetyl-coa acetyltransferase
GKS42_RS23435	ENOG4105CHR	reductase
GKS42_RS23450	ENOG410769Z	extracellular solute-binding protein family 1
GKS42_RS23455	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
GKS42_RS23460	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
GKS42_RS23475	ENOG4105ETE	Transcriptional regulator (LacI family
GKS42_RS23485	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
GKS42_RS23520	ENOG4105DSF	transport protein
GKS42_RS23530	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GKS42_RS23540	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
GKS42_RS23555	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
GKS42_RS23560	ENOG410839H	phosphoribosylformylglycinamidine synthase
GKS42_RS23570	ENOG4105C8V	SAICAR synthetase
GKS42_RS23605	ENOG4105D9U	N-acetyltransferase
GKS42_RS23640	ENOG4105CGH	5'-nucleotidase
GKS42_RS23645	ENOG4105C12	Phosphoribosylglycinamide synthetase
GKS42_RS23650	ENOG4107R9S	Malate synthase
GKS42_RS23670	ENOG4105EBR	Carboxylesterase
GKS42_RS23675	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
GKS42_RS23715	ENOG4108V0P	LemA family
GKS42_RS23720	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
GKS42_RS23725	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
GKS42_RS23745	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GKS42_RS23800	ENOG4108YZ9	Urea amidohydrolase subunit gamma
GKS42_RS23805	ENOG4105KI2	Urea amidohydrolase subunit beta
GKS42_RS23820	ENOG4107S16	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
GKS42_RS23825	ENOG4105MT3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
GKS42_RS23840	ENOG4105C22	threonyL-tRNA synthetase
GKS42_RS23850	ENOG4105C26	Dehydrogenase
GKS42_RS23855	ENOG4107RR1	TRANSCRIPTIONal
GKS42_RS23880	ENOG4105DZ6	Band 7 protein
GKS42_RS23905	ENOG4105CPQ	Dehydrogenase
GKS42_RS23910	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
GKS42_RS23915	ENOG4105CHP	RNA polymerase
GKS42_RS23925	ENOG4105EV8	ectoine hydroxylase
GKS42_RS23965	ENOG4105UNS	Pfam:DUF419
GKS42_RS24000	ENOG4107U5X	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
GKS42_RS24015	ENOG4105CS2	ec 3.2.1.21
GKS42_RS24020	ENOG4108JQ6	ABC transporter
GKS42_RS24025	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GKS42_RS24040	ENOG4105ETE	Transcriptional regulator (LacI family
GKS42_RS24050	ENOG4105KNI	merR family transcriptional Regulator
GKS42_RS24055	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
GKS42_RS24065	ENOG4105CFG	Acts as a chaperone (By similarity)
GKS42_RS24070	ENOG4108M15	ABC transporter
GKS42_RS24080	ENOG4105BZU	Histidine kinase
GKS42_RS24085	ENOG4105WH1	Two component transcriptional regulator luxr family
GKS42_RS24165	ENOG4105GRZ	Ycii-related protein
GKS42_RS24180	ENOG4108KPJ	rna polymerase sigma factor
GKS42_RS24185	ENOG4105ECP	epimerase
GKS42_RS24225	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GKS42_RS24230	ENOG4105I2S	Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity)
GKS42_RS24235	ENOG4105ENE	Histidine kinase
GKS42_RS24240	ENOG4105WH1	Two component transcriptional regulator luxr family
GKS42_RS24260	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
GKS42_RS24265	ENOG4108UCS	ABC, transporter
GKS42_RS24290	ENOG41080TA	Multiple resistance and ph regulation protein f
GKS42_RS24300	ENOG4108JPZ	Monovalent cation H antiporter subunit D
GKS42_RS24305	ENOG4108ZE9	Monovalent cation H antiporter subunit C
GKS42_RS24310	ENOG4105D65	subunit l
GKS42_RS24320	ENOG4105DHP	deoxycytidine triphosphate deaminase
GKS42_RS24330	ENOG4107SET	aldo keto reductase
GKS42_RS24340	ENOG4105D07	Signal peptide peptidase, SppA
GKS42_RS24345	ENOG4107QP8	phosphohexose isomerase
GKS42_RS24420	ENOG4105GRZ	Ycii-related protein
GKS42_RS24485	ENOG4105YIP	Tetr family transcriptional regulator
GKS42_RS24510	ENOG4108ETY	sodium dicarboxylate symporter
GKS42_RS24525	ENOG4105CHP	RNA polymerase
GKS42_RS24545	ENOG4106NZI	LysR family Transcriptional regulator
GKS42_RS24555	ENOG4105DTQ	mandelate racemase muconate lactonizing
GKS42_RS24570	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
GKS42_RS24580	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
GKS42_RS24615	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GKS42_RS24620	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GKS42_RS24625	ENOG4108J59	Extracellular solute-binding protein, family 5
GKS42_RS24645	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
GKS42_RS24665	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
GKS42_RS24695	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
GKS42_RS24700	ENOG4105CPP	Dehydrogenase, E1 component
GKS42_RS24710	ENOG4105CIH	Imidazole acetol-phosphate transaminase
GKS42_RS24715	ENOG41082T9	Membrane
GKS42_RS24740	ENOG4107ZCW	Low molecular weight phosphotyrosine protein phosphatase
GKS42_RS24760	ENOG4107QTF	adenylosuccinate lyase
GKS42_RS24770	ENOG4105C57	major facilitator superfamily
GKS42_RS24775	ENOG4107R33	ppx gppa phosphatase
GKS42_RS24785	ENOG4105VPX	protein, conserved in bacteria
GKS42_RS24805	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
GKS42_RS24825	ENOG4108M15	ABC transporter
GKS42_RS24875	ENOG4105CH6	catalase
GKS42_RS24890	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
GKS42_RS24915	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
GKS42_RS24920	ENOG4105EHG	Permease protein
GKS42_RS24925	ENOG4107R4I	Periplasmic binding protein
GKS42_RS24970	ENOG4107QKA	exodeoxyribonuclease V beta
GKS42_RS24975	ENOG4105DSY	exodeoxyribonuclease V, gamma
GKS42_RS24985	ENOG4105JDN	Copper resistance protein
GKS42_RS25040	ENOG4105WH1	Two component transcriptional regulator luxr family
GKS42_RS25055	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GKS42_RS25065	ENOG4105H3G	oxidoreductase
GKS42_RS25080	ENOG4108ZT1	Transcriptional regulator
GKS42_RS25090	ENOG4107SCK	Monooxygenase
GKS42_RS25105	ENOG4105ECR	NmrA family
GKS42_RS25145	ENOG4105CIG	ABC transporter
GKS42_RS25150	ENOG4108X07	Tetr family transcriptional regulator
GKS42_RS25160	ENOG4108ZGX	Histidine kinase
GKS42_RS25165	ENOG4105WH1	Two component transcriptional regulator luxr family
GKS42_RS25180	ENOG4105WH1	Two component transcriptional regulator luxr family
GKS42_RS25185	ENOG4105BZU	Histidine kinase
GKS42_RS25195	ENOG4107TZ2	Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity)
GKS42_RS25210	ENOG4107QX3	carboxylase
GKS42_RS25245	ENOG4105DA5	(ABC) transporter
GKS42_RS25255	ENOG4105BZU	Histidine kinase
GKS42_RS25260	ENOG4105WH1	Two component transcriptional regulator luxr family
GKS42_RS25270	ENOG4105ECR	NmrA family
GKS42_RS25275	ENOG4105KVH	Transcriptional regulator
GKS42_RS25305	ENOG4105N14	lysine exporter protein LysE YggA
GKS42_RS25330	ENOG4105E98	transcriptional regulator DeoR family
GKS42_RS25345	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
GKS42_RS25350	ENOG4105DRS	transport system, permease
GKS42_RS25370	ENOG4105F9F	transposase
GKS42_RS25390	ENOG4105CZM	Major Facilitator
GKS42_RS25420	ENOG4105ENH	Sulfatase
GKS42_RS25425	ENOG41061ZR	Transcriptional regulator
GKS42_RS25460	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GKS42_RS25515	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
GKS42_RS25540	ENOG4105PDP	Short chain dehydrogenase
GKS42_RS25545	ENOG4106JUT	Streptomycin 3''-adenylyltransferase
GKS42_RS25560	ENOG4108ZPQ	MazG nucleotide pyrophosphohydrolase
GKS42_RS25590	ENOG4105CDU	Replicative dna helicase
GKS42_RS25595	ENOG4107R73	Mate efflux family protein
GKS42_RS25670	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
GKS42_RS25700	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
GKS42_RS25705	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
GKS42_RS25715	ENOG410829C	Binds together with S18 to 16S ribosomal RNA (By similarity)
GKS42_RS25720	ENOG4105BZ4	penicillin-binding protein
GKS42_RS25730	ENOG4105CZA	synthase
GKS42_RS25735	ENOG4105CPQ	Dehydrogenase
GKS42_RS25750	ENOG4105CHP	RNA polymerase
GKS42_RS25760	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
GKS42_RS25765	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
GKS42_RS25770	ENOG4108IJG	ABC transporter substrate-binding protein
GKS42_RS25780	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
GKS42_RS25800	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GKS42_RS25820	ENOG4105C3M	thioredoxin reductase
GKS42_RS25825	ENOG4105K63	Thioredoxin
GKS42_RS25830	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
GKS42_RS25835	ENOG4105CPF	Cell wall formation (By similarity)
GKS42_RS25845	ENOG4107QJE	Chromosome Partitioning Protein
GKS42_RS25850	ENOG4107XUG	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
GKS42_RS25860	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GKS42_RS25865	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
GKS42_RS25870	ENOG4105XH8	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
GKS42_RS25875	ENOG41084CH	50S ribosomal protein l34
GKS42_RS25890	ENOG4105NPE	arsR family transcriptional regulator
GKS42_RS25965	ENOG4108097	ATP-binding protein