locus-tag	class	description
HMSLTHF_RS00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
HMSLTHF_RS00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
HMSLTHF_RS00015	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
HMSLTHF_RS00020	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HMSLTHF_RS00025	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
HMSLTHF_RS00030	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
HMSLTHF_RS00035	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
HMSLTHF_RS00040	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
HMSLTHF_RS00045	ENOG4105XA0	heptosyltransferase ii
HMSLTHF_RS00050	ENOG4107RES	phosphoglycerol transferase I
HMSLTHF_RS00055	ENOG4106WTF	Glycosyl transferase, family 2
HMSLTHF_RS00060	ENOG4105M5K	heptosyltransferase
HMSLTHF_RS00065	ENOG4105CPK	Glycosyl transferase (Group 1
HMSLTHF_RS00070	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
HMSLTHF_RS00080	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
HMSLTHF_RS00085	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
HMSLTHF_RS00090	ENOG4105E66	phosphoriboisomerase A
HMSLTHF_RS00095	ENOG4105C7B	Threonine dehydratase
HMSLTHF_RS00100	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
HMSLTHF_RS00110	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
HMSLTHF_RS00120	ENOG4107RAQ	aminopeptidase
HMSLTHF_RS00130	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
HMSLTHF_RS00135	ENOG4105CN1	protease
HMSLTHF_RS00140	ENOG41063SB	peptidase
HMSLTHF_RS00145	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HMSLTHF_RS00150	ENOG4107YZP	Rhodanese domain protein
HMSLTHF_RS00155	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
HMSLTHF_RS00160	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
HMSLTHF_RS00165	ENOG4105QNR	S1 RNA binding domain protein
HMSLTHF_RS00170	ENOG4105D7Z	glutathione synthase
HMSLTHF_RS00175	ENOG4108UJU	UPF0301 protein
HMSLTHF_RS00180	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
HMSLTHF_RS00185	ENOG4105CXT	aspartate transcarbamylase
HMSLTHF_RS00220	ENOG4108ZJT	translation initiation factor, Sui1
HMSLTHF_RS00225	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HMSLTHF_RS00240	ENOG4105D2N	Aldolase
HMSLTHF_RS00245	ENOG4105BZA	Phosphoglycerate kinase
HMSLTHF_RS00250	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HMSLTHF_RS00255	ENOG41067MG	lrgb family
HMSLTHF_RS00265	ENOG4105CV1	Transketolase (EC 2.2.1.1)
HMSLTHF_RS00270	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
HMSLTHF_RS00275	ENOG410649J	Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction (By similarity)
HMSLTHF_RS00285	ENOG4105SYT	Methylenetetrahydrofolate reductase
HMSLTHF_RS00305	ENOG4105DGW	oligopeptidase A
HMSLTHF_RS00310	ENOG4105C8J	)-transporter
HMSLTHF_RS00315	ENOG4108Z0R	Transferase
HMSLTHF_RS00325	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HMSLTHF_RS00330	ENOG4105CQZ	Histidine kinase
HMSLTHF_RS00340	ENOG4105DMF	Dehydrogenase
HMSLTHF_RS00365	ENOG4105M9M	anti-sigma28 factor FlgM
HMSLTHF_RS00370	ENOG4105CKS	Flagella basal body P-ring formation protein flgA
HMSLTHF_RS00375	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
HMSLTHF_RS00380	ENOG4108ZC9	flagellar basal-body rod protein flgc
HMSLTHF_RS00385	ENOG4105W00	Flagellar hook capping protein
HMSLTHF_RS00390	ENOG4105BZE	flagellar hook protein, FlgE
HMSLTHF_RS00395	ENOG4108KPB	Flagellar basal-body rod protein FlgF
HMSLTHF_RS00400	ENOG4105CGA	flagellar basal-body rod protein FlgG
HMSLTHF_RS00410	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
HMSLTHF_RS00415	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
HMSLTHF_RS00420	ENOG4105E1Q	flagellar hook-associated protein
HMSLTHF_RS00425	ENOG4105DTJ	flagellar hook-associated protein
HMSLTHF_RS00430	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
HMSLTHF_RS00440	ENOG4105CN7	Flagellar biosynthetic protein FliP
HMSLTHF_RS00450	ENOG4105DD5	Flagellar motor switch protein
HMSLTHF_RS00455	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
HMSLTHF_RS00460	ENOG4107ZI8	flagellar basal body-associated protein flil
HMSLTHF_RS00475	ENOG4108JIR	Flagellum-specific ATP synthase
HMSLTHF_RS00485	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
HMSLTHF_RS00490	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
HMSLTHF_RS00495	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
HMSLTHF_RS00500	ENOG41063QE	flagellar protein FlaG
HMSLTHF_RS00505	ENOG4106825	Type iv pilus assembly
HMSLTHF_RS00510	ENOG4105MQ3	flagellar protein FliS
HMSLTHF_RS00530	ENOG4105GEH	Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity)
HMSLTHF_RS00535	ENOG4106CIA	Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region
HMSLTHF_RS00540	ENOG4107RD7	Flagellar Motor Protein, MotA
HMSLTHF_RS00545	ENOG4105ER2	Ompa motb domain protein
HMSLTHF_RS00550	ENOG4105CBS	Chea signal transduction histidine kinase
HMSLTHF_RS00555	ENOG4108V3W	Chemotaxis protein, CheW
HMSLTHF_RS00565	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
HMSLTHF_RS00565	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
HMSLTHF_RS00570	ENOG4105BZU	Histidine kinase
HMSLTHF_RS00575	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
HMSLTHF_RS00580	ENOG4105C8Q	Methyl-accepting chemotaxis
HMSLTHF_RS00585	ENOG4108VYJ	response regulator receiver protein
HMSLTHF_RS00590	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
HMSLTHF_RS00595	ENOG4105D00	flagellar biosynthetic protein flhB
HMSLTHF_RS00600	ENOG4105D7B	Flagellar biosynthesis protein flha
HMSLTHF_RS00605	ENOG4105FZW	flagellar biosynthesis regulator FlhF
HMSLTHF_RS00620	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HMSLTHF_RS00625	ENOG4107R0U	MotA TolQ exbB proton channel
HMSLTHF_RS00630	ENOG4106VK6	Flagellar motor protein
HMSLTHF_RS00665	ENOG4105PGM	cation diffusion facilitator family transporter
HMSLTHF_RS00670	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
HMSLTHF_RS00675	ENOG4105FAA	peptidase M23
HMSLTHF_RS00685	ENOG4105W1Y	Transcriptional regulator
HMSLTHF_RS00690	ENOG4105C59	p-type ATPase
HMSLTHF_RS00700	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
HMSLTHF_RS00705	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
HMSLTHF_RS00735	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HMSLTHF_RS00740	ENOG4107RDB	Major Facilitator
HMSLTHF_RS00745	ENOG4108UUM	single-stranded DNA-binding protein
HMSLTHF_RS00765	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
HMSLTHF_RS00770	ENOG4105BZU	Histidine kinase
HMSLTHF_RS00775	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
HMSLTHF_RS00780	ENOG4107X2D	transcriptional regulator, merr family
HMSLTHF_RS00785	ENOG4105ECP	epimerase
HMSLTHF_RS00790	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
HMSLTHF_RS00795	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HMSLTHF_RS00815	ENOG4105C32	Amino acid ABC transporter (Permease)
HMSLTHF_RS00820	ENOG4108IV0	ABC, transporter
HMSLTHF_RS00825	ENOG4105C0Z	ABC transporter
HMSLTHF_RS00830	ENOG4105CI3	gtp-binding protein typa
HMSLTHF_RS00835	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
HMSLTHF_RS00840	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
HMSLTHF_RS00865	ENOG4105PM1	preprotein translocase subunit SecE
HMSLTHF_RS00870	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
HMSLTHF_RS00875	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
HMSLTHF_RS00880	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
HMSLTHF_RS00885	ENOG4108VZM	50s ribosomal protein L10
HMSLTHF_RS00890	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
HMSLTHF_RS00895	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HMSLTHF_RS00900	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HMSLTHF_RS00905	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
HMSLTHF_RS00910	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
HMSLTHF_RS00915	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
HMSLTHF_RS00920	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HMSLTHF_RS00925	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
HMSLTHF_RS00930	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
HMSLTHF_RS00935	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
HMSLTHF_RS00940	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
HMSLTHF_RS00945	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HMSLTHF_RS00950	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
HMSLTHF_RS00955	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
HMSLTHF_RS00960	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
HMSLTHF_RS00965	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
HMSLTHF_RS00970	ENOG41083MP	50s ribosomal protein l29
HMSLTHF_RS00975	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
HMSLTHF_RS00980	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
HMSLTHF_RS00985	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
HMSLTHF_RS00990	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HMSLTHF_RS00995	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
HMSLTHF_RS01000	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
HMSLTHF_RS01005	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
HMSLTHF_RS01010	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
HMSLTHF_RS01015	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
HMSLTHF_RS01020	ENOG4105VPB	50S ribosomal protein L30
HMSLTHF_RS01025	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
HMSLTHF_RS01030	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
HMSLTHF_RS01035	ENOG41067V7	50S ribosomal protein L36
HMSLTHF_RS01040	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HMSLTHF_RS01045	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
HMSLTHF_RS01050	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
HMSLTHF_RS01055	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HMSLTHF_RS01060	ENOG4108ZT0	50S ribosomal protein l17
HMSLTHF_RS01065	ENOG4105DZ1	carboxypeptidase
HMSLTHF_RS01070	ENOG4105DFI	Membrane
HMSLTHF_RS01075	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
HMSLTHF_RS01085	ENOG4105CC0	LysR family Transcriptional regulator
HMSLTHF_RS01090	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
HMSLTHF_RS01095	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
HMSLTHF_RS01100	ENOG4107XDR	Lactoylglutathione lyase
HMSLTHF_RS01115	ENOG4105DSE	periplasmic solute binding protein
HMSLTHF_RS01120	ENOG4105CC5	ABC transporter
HMSLTHF_RS01125	ENOG4105DIK	(ABC) transporter
HMSLTHF_RS01145	ENOG4105C5F	glutamine synthetase
HMSLTHF_RS01155	ENOG4105CUX	Signal transduction histidine kinase
HMSLTHF_RS01160	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HMSLTHF_RS01175	ENOG4106BSU	Entericidin B
HMSLTHF_RS01210	ENOG4105BZ7	extracellular solute-binding protein family 1
HMSLTHF_RS01225	ENOG4105K5B	UPF0225 protein
HMSLTHF_RS01235	ENOG4105BZU	Histidine kinase
HMSLTHF_RS01240	ENOG4105VC4	domain protein
HMSLTHF_RS01255	ENOG4105F2V	VRR-NUC domain-containing protein
HMSLTHF_RS01270	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HMSLTHF_RS01405	ENOG4105EAH	synthase
HMSLTHF_RS01410	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
HMSLTHF_RS01415	ENOG4105K46	50S ribosomal protein l27
HMSLTHF_RS01420	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HMSLTHF_RS01425	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
HMSLTHF_RS01445	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HMSLTHF_RS01450	ENOG41062D9	Histidine kinase
HMSLTHF_RS01460	ENOG4105BZU	Histidine kinase
HMSLTHF_RS01475	ENOG4105S7S	phosphonate abc transporter
HMSLTHF_RS01495	ENOG4105C8Q	Methyl-accepting chemotaxis
HMSLTHF_RS01500	ENOG4105BZU	Histidine kinase
HMSLTHF_RS01525	ENOG4105DN9	Na H antiporter
HMSLTHF_RS01535	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
HMSLTHF_RS01540	ENOG4108Z1B	Cyclase dehydrase
HMSLTHF_RS01545	ENOG4105VDB	UPF0125 protein
HMSLTHF_RS01550	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HMSLTHF_RS01555	ENOG41090R7	Ferric uptake
HMSLTHF_RS01560	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
HMSLTHF_RS01565	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HMSLTHF_RS01570	ENOG4105CFG	Acts as a chaperone (By similarity)
HMSLTHF_RS01575	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HMSLTHF_RS01585	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
HMSLTHF_RS01600	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
HMSLTHF_RS01605	ENOG4105HBR	Rna-binding protein
HMSLTHF_RS01610	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
HMSLTHF_RS01615	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HMSLTHF_RS01620	ENOG4105EEI	dihydropteroate synthase
HMSLTHF_RS01625	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
HMSLTHF_RS01630	ENOG4105CP7	Triose-phosphate isomerase
HMSLTHF_RS01635	ENOG4105NTZ	Preprotein translocase subunit SecG
HMSLTHF_RS01650	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
HMSLTHF_RS01655	ENOG4105CHV	Transcription elongation factor NusA
HMSLTHF_RS01660	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
HMSLTHF_RS01665	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
HMSLTHF_RS01670	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
HMSLTHF_RS01675	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
HMSLTHF_RS01680	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
HMSLTHF_RS01685	ENOG4107RTG	Major Facilitator superfamily
HMSLTHF_RS01690	ENOG4105CHU	acetyl-coa acetyltransferase
HMSLTHF_RS01695	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
HMSLTHF_RS01700	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
HMSLTHF_RS01705	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
HMSLTHF_RS01710	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HMSLTHF_RS01715	ENOG4105DJ0	Poly(A) Polymerase
HMSLTHF_RS01720	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HMSLTHF_RS01725	ENOG4105BZU	Histidine kinase
HMSLTHF_RS01735	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
HMSLTHF_RS01750	ENOG4105PW4	Sugar fermentation stimulation protein homolog
HMSLTHF_RS01770	ENOG4108VIA	integral membrane protein
HMSLTHF_RS01775	ENOG4105II7	pyrroline-5-carboxylate reductase
HMSLTHF_RS01780	ENOG4105DFA	alanine racemase domain protein
HMSLTHF_RS01785	ENOG4105CZX	twitching motility protein
HMSLTHF_RS01790	ENOG4105CZX	twitching motility protein
HMSLTHF_RS01795	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
HMSLTHF_RS01800	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
HMSLTHF_RS01835	ENOG4105D1Q	UPF0246 protein
HMSLTHF_RS01840	ENOG4105CPC	Aldo Keto reductase
HMSLTHF_RS01855	ENOG4108URH	decarboxylase
HMSLTHF_RS01890	ENOG4105C87	Aminotransferase class I and II
HMSLTHF_RS01895	ENOG4107QR8	Thioredoxin
HMSLTHF_RS01925	ENOG4105KPV	Transcriptional regulator
HMSLTHF_RS01930	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
HMSLTHF_RS01945	ENOG4108YY7	Invasion gene expression up-regulator SirB
HMSLTHF_RS01955	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
HMSLTHF_RS01960	ENOG4105CVR	type I restriction-modification system
HMSLTHF_RS01965	ENOG4107XZC	Restriction modification system DNA (Specificity
HMSLTHF_RS01975	ENOG4105CHR	reductase
HMSLTHF_RS01985	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
HMSLTHF_RS01990	ENOG4107QMS	site-determining protein
HMSLTHF_RS01995	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
HMSLTHF_RS02000	ENOG4105CJB	Exodeoxyribonuclease I
HMSLTHF_RS02005	ENOG4107QXK	peptidase
HMSLTHF_RS02025	ENOG4108JU6	CBS domain protein
HMSLTHF_RS02030	ENOG4106KVJ	cytochrome C assembly protein
HMSLTHF_RS02035	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HMSLTHF_RS02040	ENOG4105K5M	30s ribosomal protein S16
HMSLTHF_RS02045	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
HMSLTHF_RS02050	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
HMSLTHF_RS02055	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
HMSLTHF_RS02060	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HMSLTHF_RS02065	ENOG4105T95	Thiol disulfide interChange protein
HMSLTHF_RS02070	ENOG4105D6E	homoserine dehydrogenase
HMSLTHF_RS02075	ENOG4105D98	threonine synthase
HMSLTHF_RS02080	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
HMSLTHF_RS02090	ENOG4105C59	p-type ATPase
HMSLTHF_RS02100	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
HMSLTHF_RS02110	ENOG4105CRK	lysyL-tRNA synthetase
HMSLTHF_RS02120	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HMSLTHF_RS02125	ENOG4105M85	Bola protein
HMSLTHF_RS02140	ENOG4105N4M	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
HMSLTHF_RS02145	ENOG4106H78	methyltransferase
HMSLTHF_RS02150	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HMSLTHF_RS02155	ENOG4105CAK	Cell division ATP-binding protein ftsE
HMSLTHF_RS02160	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
HMSLTHF_RS02165	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HMSLTHF_RS02170	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
HMSLTHF_RS02175	ENOG4105CAS	nag kinase
HMSLTHF_RS02180	ENOG4107QKV	phosphomannomutase
HMSLTHF_RS02190	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
HMSLTHF_RS02195	ENOG4105W5Q	DNA repair protein (RadC
HMSLTHF_RS02200	ENOG4105KDC	50s ribosomal protein l28
HMSLTHF_RS02205	ENOG4105W0E	50S ribosomal protein L33
HMSLTHF_RS02210	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
HMSLTHF_RS02215	ENOG4105DR4	Methyltransferase
HMSLTHF_RS02225	ENOG4105VEQ	Cold shock protein
HMSLTHF_RS02235	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
HMSLTHF_RS02250	ENOG4107QSS	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli (By similarity)
HMSLTHF_RS02255	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
HMSLTHF_RS02260	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HMSLTHF_RS02265	ENOG4105CE9	30S ribosomal protein S2
HMSLTHF_RS02270	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
HMSLTHF_RS02275	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
HMSLTHF_RS02280	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
HMSLTHF_RS02285	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
HMSLTHF_RS02290	ENOG4105KNE	Phosphatidate cytidylyltransferase
HMSLTHF_RS02295	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
HMSLTHF_RS02300	ENOG4105DZP	Membrane-associated zinc metalloprotease
HMSLTHF_RS02315	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HMSLTHF_RS02320	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
HMSLTHF_RS02325	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HMSLTHF_RS02330	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HMSLTHF_RS02335	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HMSLTHF_RS02340	ENOG4105C0B	DNA polymerase III (alpha subunit)
HMSLTHF_RS02345	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
HMSLTHF_RS02350	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
HMSLTHF_RS02355	ENOG4105C9X	ppx gppa phosphatase
HMSLTHF_RS02360	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
HMSLTHF_RS02365	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
HMSLTHF_RS02370	ENOG4107QK7	reductase
HMSLTHF_RS02380	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HMSLTHF_RS02395	ENOG4105S2T	inner membrane protein YbcI
HMSLTHF_RS02410	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
HMSLTHF_RS02425	ENOG4105CM2	brancheD-chain amino acid aminotransferase
HMSLTHF_RS02430	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HMSLTHF_RS02435	ENOG4108M8S	permease YjgP YjgQ family protein
HMSLTHF_RS02440	ENOG4108K5H	permease YjgP YjgQ family protein
HMSLTHF_RS02455	ENOG4108UQY	Iron-storage protein
HMSLTHF_RS02465	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HMSLTHF_RS02475	ENOG4105DR9	pseudouridine synthase
HMSLTHF_RS02480	ENOG4105CUZ	uba thif-type nad fad binding protein
HMSLTHF_RS02490	ENOG4107QPB	Beta-lactamase domain protein
HMSLTHF_RS02505	ENOG4105CKI	cobalamin synthesis protein
HMSLTHF_RS02515	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HMSLTHF_RS02525	ENOG4105CPD	ethanolamine ammonia-lyase
HMSLTHF_RS02535	ENOG4105CUB	amino acid
HMSLTHF_RS02545	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
HMSLTHF_RS02550	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
HMSLTHF_RS02560	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
HMSLTHF_RS02565	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
HMSLTHF_RS02570	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
HMSLTHF_RS02575	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HMSLTHF_RS02580	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
HMSLTHF_RS02590	ENOG4106IUH	DTW domain containing protein
HMSLTHF_RS02605	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
HMSLTHF_RS02610	ENOG4105C1A	potassium transporter peripheral membrane
HMSLTHF_RS02615	ENOG4105WKW	Pfam:DUF1458
HMSLTHF_RS02620	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HMSLTHF_RS02625	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
HMSLTHF_RS02630	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HMSLTHF_RS02640	ENOG4105D7V	transposase
HMSLTHF_RS02645	ENOG4105C79	DNA protecting protein DprA
HMSLTHF_RS02650	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HMSLTHF_RS02655	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
HMSLTHF_RS02660	ENOG4105E2X	shikimate dehydrogenase
HMSLTHF_RS02685	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
HMSLTHF_RS02690	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HMSLTHF_RS02695	ENOG4105N21	Membrane
HMSLTHF_RS02700	ENOG4105CUT	histidyl-tRNA synthetase
HMSLTHF_RS02705	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
HMSLTHF_RS02715	ENOG4105CFV	Tetratricopeptide repeat protein
HMSLTHF_RS02720	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HMSLTHF_RS02725	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
HMSLTHF_RS02735	ENOG4105C3J	Cysteine desulfurase
HMSLTHF_RS02740	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
HMSLTHF_RS02745	ENOG4105D7W	serine acetyltransferase
HMSLTHF_RS02755	ENOG4105ECY	inositol monophosphatase
HMSLTHF_RS02760	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HMSLTHF_RS02765	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HMSLTHF_RS02770	ENOG4105VIE	preprotein translocase, subunit YajC
HMSLTHF_RS02775	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
HMSLTHF_RS02780	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
HMSLTHF_RS02790	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HMSLTHF_RS02830	ENOG4108UW5	maltose o-acetyltransferase
HMSLTHF_RS02835	ENOG4106H3A	restriction
HMSLTHF_RS02910	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
HMSLTHF_RS02915	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
HMSLTHF_RS02920	ENOG4105CNG	UPF0061 protein
HMSLTHF_RS02925	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HMSLTHF_RS02940	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HMSLTHF_RS02945	ENOG4105C58	cytochrome c oxidase accessory protein ccog
HMSLTHF_RS02955	ENOG4108JPW	Aminotransferase
HMSLTHF_RS02965	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HMSLTHF_RS02970	ENOG4105C1G	acyl-Coa dehydrogenase
HMSLTHF_RS02975	ENOG4108PVQ	transcriptional regulator
HMSLTHF_RS02980	ENOG4105D5U	fad dependent oxidoreductase
HMSLTHF_RS03000	ENOG4108JQC	penicillin-binding protein 1A
HMSLTHF_RS03025	ENOG4105E4G	Type IV pilus
HMSLTHF_RS03030	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HMSLTHF_RS03035	ENOG4105D49	3-dehydroquinate synthase
HMSLTHF_RS03040	ENOG4105CBC	glutamate synthase
HMSLTHF_RS03045	ENOG4105BZ8	glutamate synthase
HMSLTHF_RS03050	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
HMSLTHF_RS03055	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
HMSLTHF_RS03060	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
HMSLTHF_RS03065	ENOG4108Z4U	Ferredoxin
HMSLTHF_RS03070	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
HMSLTHF_RS03075	ENOG4107TH8	cina domain protein
HMSLTHF_RS03080	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
HMSLTHF_RS03165	ENOG4108IJF	Heavy metal efflux pump, CzcA
HMSLTHF_RS03170	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
HMSLTHF_RS03245	ENOG4107QIV	Cytochrome c biogenesis protein
HMSLTHF_RS03255	ENOG4107ZT5	Thiol disulfide interchange protein
HMSLTHF_RS03285	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
HMSLTHF_RS03315	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
HMSLTHF_RS03320	ENOG4107QX9	Thiol disulfide interChange protein
HMSLTHF_RS03325	ENOG4108N5C	SNARE associated Golgi protein-related protein
HMSLTHF_RS03330	ENOG4108KHN	disulfide isomerase, thiol-disulfide oxidase
HMSLTHF_RS03345	ENOG4105D3R	alkyl hydroperoxide reductase
HMSLTHF_RS03350	ENOG4107QIV	Cytochrome c biogenesis protein
HMSLTHF_RS03385	ENOG4105BZU	Histidine kinase
HMSLTHF_RS03450	ENOG4107Y80	Major Facilitator superfamily
HMSLTHF_RS03505	ENOG4105Y3E	Modulates RecA activity (By similarity)
HMSLTHF_RS03510	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HMSLTHF_RS03515	ENOG4105CFH	Aspartokinase
HMSLTHF_RS03520	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
HMSLTHF_RS03540	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
HMSLTHF_RS03550	ENOG4107QSA	Oxaloacetate decarboxylase
HMSLTHF_RS03555	ENOG4105D9Q	decarboxylase (Beta subunit)
HMSLTHF_RS03560	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
HMSLTHF_RS03570	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
HMSLTHF_RS03575	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
HMSLTHF_RS03580	ENOG41060IM	Heme exporter protein
HMSLTHF_RS03590	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
HMSLTHF_RS03595	ENOG4105DA4	cytochrome c-type biogenesis protein
HMSLTHF_RS03600	ENOG4107QX9	Thiol disulfide interChange protein
HMSLTHF_RS03605	ENOG4105KWW	Biogenesis protein
HMSLTHF_RS03615	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
HMSLTHF_RS03620	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
HMSLTHF_RS03625	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
HMSLTHF_RS03630	ENOG4106851	UPF0270 protein
HMSLTHF_RS03635	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
HMSLTHF_RS03640	ENOG4105K9H	YciI-like protein
HMSLTHF_RS03645	ENOG4105DB7	PHP domain protein
HMSLTHF_RS03650	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
HMSLTHF_RS03655	ENOG4105EYW	Ion transport protein
HMSLTHF_RS03665	ENOG4107IX6	phosphate transport regulator
HMSLTHF_RS03670	ENOG4105CJ3	phosphate transporter
HMSLTHF_RS03700	ENOG4107QZM	n-acetylglutamate synthase
HMSLTHF_RS03710	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HMSLTHF_RS03725	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HMSLTHF_RS03730	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HMSLTHF_RS03735	ENOG4105EQ2	LysR family Transcriptional regulator
HMSLTHF_RS03740	ENOG4105W1Y	Transcriptional regulator
HMSLTHF_RS03745	ENOG4105PGM	cation diffusion facilitator family transporter
HMSLTHF_RS03805	ENOG4105CKW	Inner membrane protein yedI
HMSLTHF_RS03840	ENOG4105HEI	LysR family (Transcriptional regulator
HMSLTHF_RS03845	ENOG4105NF4	modulator of drug activity
HMSLTHF_RS03860	ENOG4105CEY	Amp-dependent synthetase and ligase
HMSLTHF_RS03865	ENOG4105DHI	Methyltransferase
HMSLTHF_RS03870	ENOG4105VEQ	Cold shock protein
HMSLTHF_RS03895	ENOG4105CHB	tonB-dependent Receptor
HMSLTHF_RS03900	ENOG4105DZG	Dehydrogenase
HMSLTHF_RS03905	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
HMSLTHF_RS03910	ENOG4105K6T	rare lipoprotein A
HMSLTHF_RS03925	ENOG4105D7V	transposase
HMSLTHF_RS03945	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
HMSLTHF_RS03950	ENOG4105IBP	Cyclic peptide transporter
HMSLTHF_RS03955	ENOG4105E0A	ABC, transporter
HMSLTHF_RS03965	ENOG4108KPJ	rna polymerase sigma factor
HMSLTHF_RS04015	ENOG4105J76	Periplasmic binding protein
HMSLTHF_RS04025	ENOG4105F1Y	L-lysine 6-monooxygenase (NADPH)
HMSLTHF_RS04035	ENOG4105IBP	Cyclic peptide transporter
HMSLTHF_RS04060	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
HMSLTHF_RS04070	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
HMSLTHF_RS04075	ENOG4105C5W	Aldolase
HMSLTHF_RS04080	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
HMSLTHF_RS04085	ENOG4108HK0	-acetyltransferase
HMSLTHF_RS04125	ENOG4107QZF	nitrite reductase NADPH large subunit
HMSLTHF_RS04130	ENOG4108IFG	nitrite reductase, (NAD(P)H)
HMSLTHF_RS04160	ENOG4105FGV	Chromate
HMSLTHF_RS04165	ENOG4105FGV	Chromate
HMSLTHF_RS04170	ENOG4108WYP	Transcriptional regulator
HMSLTHF_RS04190	ENOG4105DEN	Luciferase family
HMSLTHF_RS04195	ENOG4105EMU	Dehydrogenase
HMSLTHF_RS04225	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
HMSLTHF_RS04230	ENOG4105DR5	peptidase
HMSLTHF_RS04235	ENOG4105C5Q	Transcriptional regulator
HMSLTHF_RS04240	ENOG4105CHF	Glutathione S-transferase
HMSLTHF_RS04255	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
HMSLTHF_RS04260	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HMSLTHF_RS04265	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
HMSLTHF_RS04270	ENOG4108Z86	Glutamine amidotransferase
HMSLTHF_RS04280	ENOG4105D8X	mechanosensitive ion channel
HMSLTHF_RS04310	ENOG4107TYG	Oxidoreductase domain-containing protein
HMSLTHF_RS04315	ENOG4107T3P	ABC, transporter
HMSLTHF_RS04320	ENOG4105ETE	Transcriptional regulator (LacI family
HMSLTHF_RS04330	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
HMSLTHF_RS04335	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
HMSLTHF_RS04340	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
HMSLTHF_RS04350	ENOG4105D9N	nucleoside
HMSLTHF_RS04355	ENOG4108NFH	Sugar hydrolase
HMSLTHF_RS04360	ENOG4107FB0	transcriptional regulator DeoR family
HMSLTHF_RS04365	ENOG4105E2S	oxidase) subunit II
HMSLTHF_RS04370	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HMSLTHF_RS04375	ENOG4105CCU	oxidase (Subunit III)
HMSLTHF_RS04380	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
HMSLTHF_RS04385	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
HMSLTHF_RS04390	ENOG4108DNC	Involved in acetate metabolism (By similarity)
HMSLTHF_RS04395	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
HMSLTHF_RS04410	ENOG4105EFX	secretion protein, HlyD family
HMSLTHF_RS04445	ENOG4105CBP	Major Facilitator
HMSLTHF_RS04455	ENOG4105ETU	transcriptional activator (TenA
HMSLTHF_RS04545	ENOG41084HI	prevent-host-death family
HMSLTHF_RS04555	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
HMSLTHF_RS04570	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
HMSLTHF_RS04590	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
HMSLTHF_RS04605	ENOG4105CSU	acyl-Coa dehydrogenase
HMSLTHF_RS04610	ENOG4105CEY	Amp-dependent synthetase and ligase
HMSLTHF_RS04615	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HMSLTHF_RS04620	ENOG4105E39	Enoyl-CoA hydratase
HMSLTHF_RS04630	ENOG4108TGY	Glutathione S-transferase
HMSLTHF_RS04635	ENOG4108VWS	Yaeq family
HMSLTHF_RS04655	ENOG4105E0K	tonB-dependent siderophore receptor
HMSLTHF_RS04665	ENOG4105CYM	Glutathione S-transferase
HMSLTHF_RS04670	ENOG4105K56	Transcriptional regulator
HMSLTHF_RS04675	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
HMSLTHF_RS04685	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HMSLTHF_RS04690	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
HMSLTHF_RS04695	ENOG4105DIQ	Transcriptional regulator
HMSLTHF_RS04710	ENOG4108Z9K	Osmotically inducible protein
HMSLTHF_RS04715	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
HMSLTHF_RS04720	ENOG4108ZXC	Two component transcriptional regulator, luxr family
HMSLTHF_RS04725	ENOG4105BZU	Histidine kinase
HMSLTHF_RS04745	ENOG4105EGD	dinuclear metal center protein, YbgI family
HMSLTHF_RS04755	ENOG4108V7B	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity)
HMSLTHF_RS04775	ENOG4108JUA	Transcriptional regulator
HMSLTHF_RS04780	ENOG4105DFG	type I secretion outer membrane protein
HMSLTHF_RS04785	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HMSLTHF_RS04815	ENOG4105CH6	catalase
HMSLTHF_RS04820	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HMSLTHF_RS04835	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
HMSLTHF_RS04850	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HMSLTHF_RS04855	ENOG4105BZN	citrate synthase
HMSLTHF_RS04860	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
HMSLTHF_RS04865	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
HMSLTHF_RS04870	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
HMSLTHF_RS04875	ENOG4105E33	succinate dehydrogenase
HMSLTHF_RS04880	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
HMSLTHF_RS04885	ENOG4105C7S	Dehydrogenase
HMSLTHF_RS04890	ENOG4107QN2	dihydrolipoyl dehydrogenase
HMSLTHF_RS04895	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
HMSLTHF_RS04900	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
HMSLTHF_RS04910	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HMSLTHF_RS04920	ENOG4108AZI	Catalyzes the hydrolysis of 4-amino-2-methyl-5- hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2- methyl-5-hydroxymethylpyrimidine phosphate (HMP-P) (By similarity)
HMSLTHF_RS04935	ENOG4105CM6	amino acid regulated cytosolic protein
HMSLTHF_RS04945	ENOG4105DSB	aldose 1-epimerase
HMSLTHF_RS04960	ENOG4107TT5	NLP P60 protein
HMSLTHF_RS04965	ENOG4105D94	Major Facilitator Superfamily
HMSLTHF_RS04970	ENOG4105EFJ	Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity)
HMSLTHF_RS04980	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HMSLTHF_RS04990	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
HMSLTHF_RS04995	ENOG4105MRR	Transcriptional regulator (By similarity)
HMSLTHF_RS05000	ENOG4108YZY	peptidylprolyl cis-trans isomerase
HMSLTHF_RS05010	ENOG4108XTF	Outer Membrane Lipoprotein
HMSLTHF_RS05015	ENOG4107RET	Isocitrate lyase
HMSLTHF_RS05020	ENOG4108HPG	-acetyltransferase
HMSLTHF_RS05025	ENOG4105EZE	Cupin 4 family protein
HMSLTHF_RS05030	ENOG4107QTF	adenylosuccinate lyase
HMSLTHF_RS05035	ENOG41075W9	High frequency lysogenization protein HflD homolog
HMSLTHF_RS05040	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
HMSLTHF_RS05055	ENOG4105E9K	Isocitrate dehydrogenase
HMSLTHF_RS05060	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
HMSLTHF_RS05065	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HMSLTHF_RS05070	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
HMSLTHF_RS05075	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
HMSLTHF_RS05080	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
HMSLTHF_RS05085	ENOG4105CNU	cell division protein FtsK
HMSLTHF_RS05090	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
HMSLTHF_RS05095	ENOG4105D1H	recombination factor protein RarA
HMSLTHF_RS05105	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
HMSLTHF_RS05110	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
HMSLTHF_RS05115	ENOG4105C7I	Dehydrogenase
HMSLTHF_RS05120	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
HMSLTHF_RS05125	ENOG4105WFT	During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity)
HMSLTHF_RS05130	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
HMSLTHF_RS05145	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
HMSLTHF_RS05150	ENOG4105D0M	Protease HtpX homolog
HMSLTHF_RS05155	ENOG4105CHM	Aminotransferase
HMSLTHF_RS05160	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
HMSLTHF_RS05165	ENOG4105E0X	reductase
HMSLTHF_RS05170	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HMSLTHF_RS05175	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HMSLTHF_RS05185	ENOG4105CH5	extracellular solute-binding protein, family 7
HMSLTHF_RS05225	ENOG4105DA5	(ABC) transporter
HMSLTHF_RS05230	ENOG4105E3A	(ABC) transporter
HMSLTHF_RS05235	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
HMSLTHF_RS05240	ENOG41069NU	Nitroreductase
HMSLTHF_RS05255	ENOG4105BZU	Histidine kinase
HMSLTHF_RS05270	ENOG4105CBP	Major Facilitator
HMSLTHF_RS05275	ENOG4105C8J	)-transporter
HMSLTHF_RS05290	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
HMSLTHF_RS05300	ENOG4108DG9	Smr protein MutS2
HMSLTHF_RS05305	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
HMSLTHF_RS05310	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
HMSLTHF_RS05325	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
HMSLTHF_RS05335	ENOG4108JU5	Magnesium and cobalt efflux protein
HMSLTHF_RS05340	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
HMSLTHF_RS05345	ENOG4105C9A	Phoh family
HMSLTHF_RS05350	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
HMSLTHF_RS05370	ENOG41082YX	Transcriptional regulator, arsr family
HMSLTHF_RS05375	ENOG4105CN1	protease
HMSLTHF_RS05380	ENOG4105DFM	M18 family aminopeptidase
HMSLTHF_RS05390	ENOG4105C3G	gtp-binding protein
HMSLTHF_RS05395	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
HMSLTHF_RS05400	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
HMSLTHF_RS05405	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HMSLTHF_RS05415	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
HMSLTHF_RS05420	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
HMSLTHF_RS05425	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
HMSLTHF_RS05430	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
HMSLTHF_RS05435	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
HMSLTHF_RS05440	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HMSLTHF_RS05445	ENOG4105EW9	transcriptional regulator AsnC family
HMSLTHF_RS05450	ENOG4105D06	uba thif-type nad fad binding protein
HMSLTHF_RS05455	ENOG4108JU3	Alkyl hydroperoxide reductase
HMSLTHF_RS05460	ENOG4105D3R	alkyl hydroperoxide reductase
HMSLTHF_RS05465	ENOG4108HM4	ABC transporter
HMSLTHF_RS05470	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HMSLTHF_RS05475	ENOG4105F38	ABC transporter, permease
HMSLTHF_RS05480	ENOG4105D38	putrescine abc transporter
HMSLTHF_RS05495	ENOG4105BZS	acriflavin resistance protein
HMSLTHF_RS05505	ENOG4105CBX	hi0933 family
HMSLTHF_RS05520	ENOG4105NE1	Conserved Protein
HMSLTHF_RS05525	ENOG4105HDD	phospholipase
HMSLTHF_RS05530	ENOG4105EGS	Mechanosensitive ion channel
HMSLTHF_RS05535	ENOG4105DX0	Hemolysin A
HMSLTHF_RS05545	ENOG4106MWK	domain protein
HMSLTHF_RS05550	ENOG4105FQ6	thiopurine methyltransferase
HMSLTHF_RS05560	ENOG4108IJ6	ABC transporter
HMSLTHF_RS05565	ENOG4105ECW	sulfate abc transporter
HMSLTHF_RS05570	ENOG4108I5D	sulfate abc transporter
HMSLTHF_RS05575	ENOG4108J2H	Sulfate ABC transporter periplasmic sulfate-binding protein
HMSLTHF_RS05580	ENOG4105DJV	ribulose-phosphate 3-epimerase
HMSLTHF_RS05585	ENOG4105CEP	NADH dehydrogenase
HMSLTHF_RS05595	ENOG4105DSE	periplasmic solute binding protein
HMSLTHF_RS05605	ENOG4108IEG	Formate dehydrogenase Alpha subunit
HMSLTHF_RS05610	ENOG4105DDQ	anthranilate synthase
HMSLTHF_RS05615	ENOG4107QYG	anthranilate phosphoribosyltransferase
HMSLTHF_RS05620	ENOG4105DK0	Indole-3-glycerol phosphate synthase
HMSLTHF_RS05625	ENOG4105CQB	FAD linked oxidase domain protein
HMSLTHF_RS05640	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
HMSLTHF_RS05665	ENOG4105BZU	Histidine kinase
HMSLTHF_RS05705	ENOG4105DSF	transport protein
HMSLTHF_RS05710	ENOG4105K63	Thioredoxin
HMSLTHF_RS05715	ENOG4107R11	Transcriptional regulator
HMSLTHF_RS05720	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
HMSLTHF_RS05730	ENOG4105DRR	Transcriptional regulator, GntR family
HMSLTHF_RS05735	ENOG4105CR4	methylisocitrate lyase
HMSLTHF_RS05740	ENOG4105BZN	citrate synthase
HMSLTHF_RS05745	ENOG4108I0Z	Aconitate hydratase
HMSLTHF_RS05750	ENOG4105C7F	AcnD-accessory protein PrpF
HMSLTHF_RS05760	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
HMSLTHF_RS05765	ENOG4105CFV	Tetratricopeptide repeat protein
HMSLTHF_RS05775	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HMSLTHF_RS05780	ENOG4105Y75	tpr repeat protein
HMSLTHF_RS05785	ENOG4108IYU	L-aspartate oxidase
HMSLTHF_RS05810	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
HMSLTHF_RS05835	ENOG4105DBV	ornithine carbamoyltransferase
HMSLTHF_RS05840	ENOG4105M2J	Glutaredoxin
HMSLTHF_RS05845	ENOG4107QMP	dna polymerase iii subunits gamma and tau
HMSLTHF_RS05850	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
HMSLTHF_RS05855	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
HMSLTHF_RS05865	ENOG4105VNG	YcgL domain-containing protein
HMSLTHF_RS05870	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
HMSLTHF_RS05875	ENOG4108ZZ3	UPF0260 protein
HMSLTHF_RS05890	ENOG4105E7A	Glutamine amidotransferase
HMSLTHF_RS05895	ENOG4105CEY	Amp-dependent synthetase and ligase
HMSLTHF_RS05900	ENOG4105CQ7	ATP-dependent helicase
HMSLTHF_RS05910	ENOG410903C	(LipO)protein
HMSLTHF_RS05925	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HMSLTHF_RS05930	ENOG4105C2C	drug resistance transporter, Bcr CflA
HMSLTHF_RS05945	ENOG4105C8U	phosphate abc transporter
HMSLTHF_RS05955	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
HMSLTHF_RS05960	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HMSLTHF_RS05980	ENOG4108YYH	Nadph-dependent fmn reductase
HMSLTHF_RS05985	ENOG4105D6J	arsenicaL-resistance protein
HMSLTHF_RS05990	ENOG4105CAU	Arsenical resistance protein, ArsH
HMSLTHF_RS06000	ENOG4105C8Q	Methyl-accepting chemotaxis
HMSLTHF_RS06005	ENOG4105CHU	acetyl-coa acetyltransferase
HMSLTHF_RS06010	ENOG4108RZE	Tetr family transcriptional regulator
HMSLTHF_RS06025	ENOG4105CSU	acyl-Coa dehydrogenase
HMSLTHF_RS06045	ENOG4105NXH	GreA GreB family elongation factor
HMSLTHF_RS06050	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
HMSLTHF_RS06060	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
HMSLTHF_RS06070	ENOG4107QI1	Mate efflux family protein
HMSLTHF_RS06075	ENOG4108BPE	-transporting atpase
HMSLTHF_RS06085	ENOG4105F8V	Hydrolase, tatD family
HMSLTHF_RS06100	ENOG4105C1G	acyl-Coa dehydrogenase
HMSLTHF_RS06105	ENOG4105CHU	acetyl-coa acetyltransferase
HMSLTHF_RS06110	ENOG4105CEY	Amp-dependent synthetase and ligase
HMSLTHF_RS06120	ENOG4105C5H	ABC transporter
HMSLTHF_RS06125	ENOG41081QV	Universal stress protein
HMSLTHF_RS06150	ENOG4105CHU	acetyl-coa acetyltransferase
HMSLTHF_RS06165	ENOG4108V1U	phospholipid-binding protein
HMSLTHF_RS06170	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
HMSLTHF_RS06185	ENOG4105C3K	feS assembly ATPase SufC
HMSLTHF_RS06195	ENOG4105C9B	Cysteine desulfurase
HMSLTHF_RS06205	ENOG4107GZ4	SanA protein
HMSLTHF_RS06215	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
HMSLTHF_RS06230	ENOG4105WP7	tRNA pseudouridine synthase C
HMSLTHF_RS06235	ENOG4105EIF	outer membrane protein W
HMSLTHF_RS06240	ENOG4105CK7	Sodium proline symporter
HMSLTHF_RS06245	ENOG4105C26	Dehydrogenase
HMSLTHF_RS06270	ENOG4105EMK	carboxylate amino acid amine transporter
HMSLTHF_RS06275	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
HMSLTHF_RS06310	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
HMSLTHF_RS06315	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HMSLTHF_RS06365	ENOG4105C0D	helicase
HMSLTHF_RS06370	ENOG4107QMH	DNA methylase
HMSLTHF_RS06380	ENOG4107QP8	phosphohexose isomerase
HMSLTHF_RS06385	ENOG4105DM4	PTS System
HMSLTHF_RS06390	ENOG4105DE4	1-phosphofructokinase
HMSLTHF_RS06395	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
HMSLTHF_RS06400	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
HMSLTHF_RS06405	ENOG4108Z5K	methylglyoxal synthase
HMSLTHF_RS06410	ENOG4105CA9	Pyruvate kinase
HMSLTHF_RS06415	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HMSLTHF_RS06430	ENOG4105CG3	alpha amylase, catalytic region
HMSLTHF_RS06445	ENOG4107T3P	ABC, transporter
HMSLTHF_RS06455	ENOG41061ZR	Transcriptional regulator
HMSLTHF_RS06460	ENOG4105CG3	alpha amylase, catalytic region
HMSLTHF_RS06470	ENOG4105KSC	Transcriptional regulator, TraR DksA family
HMSLTHF_RS06475	ENOG4105EG2	ABC transporter, permease
HMSLTHF_RS06480	ENOG4105D56	permease protein
HMSLTHF_RS06485	ENOG4107FKK	extracellular solute-binding protein family 1
HMSLTHF_RS06490	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
HMSLTHF_RS06495	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
HMSLTHF_RS06500	ENOG4108UHU	Aldolase
HMSLTHF_RS06505	ENOG4108HKT	sucrose-6-phosphate hydrolase
HMSLTHF_RS06510	ENOG4105D7K	pfkb domain protein
HMSLTHF_RS06520	ENOG4105CHC	glucokinase (EC 2.7.1.2)
HMSLTHF_RS06525	ENOG4105C01	Dihydroxy-acid dehydratase
HMSLTHF_RS06545	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
HMSLTHF_RS06550	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
HMSLTHF_RS06555	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HMSLTHF_RS06565	ENOG4107XPA	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
HMSLTHF_RS06570	ENOG4105CVJ	phosphoglycerate mutase
HMSLTHF_RS06580	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HMSLTHF_RS06585	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
HMSLTHF_RS06590	ENOG4105EHG	Permease protein
HMSLTHF_RS06595	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
HMSLTHF_RS06600	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
HMSLTHF_RS06605	ENOG4108V0E	nucleoside 2-deoxyribosyltransferase YtoQ
HMSLTHF_RS06610	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
HMSLTHF_RS06760	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HMSLTHF_RS06765	ENOG4105CSV	Glutaminase
HMSLTHF_RS06775	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
HMSLTHF_RS06780	ENOG4105KME	endoribonuclease L-psp
HMSLTHF_RS06785	ENOG4105EJC	lysr family transcriptional regulator
HMSLTHF_RS06795	ENOG4105BZW	Glycerate kinase
HMSLTHF_RS06820	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HMSLTHF_RS06825	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
HMSLTHF_RS06840	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
HMSLTHF_RS06850	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
HMSLTHF_RS06855	ENOG4107YNJ	LysR family Transcriptional regulator
HMSLTHF_RS06860	ENOG4108JQ7	(ABC) transporter
HMSLTHF_RS06870	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HMSLTHF_RS06875	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HMSLTHF_RS06895	ENOG4105DFU	Cell wall formation (By similarity)
HMSLTHF_RS06900	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HMSLTHF_RS06905	ENOG410829K	Lysine exporter protein (Lyse ygga)
HMSLTHF_RS06910	ENOG4108KF1	Membrane
HMSLTHF_RS06925	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
HMSLTHF_RS06930	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
HMSLTHF_RS06940	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
HMSLTHF_RS06945	ENOG4105CJN	penicillin-binding protein
HMSLTHF_RS06950	ENOG4105CNI	cell division protein FtsW
HMSLTHF_RS06955	ENOG4105CVE	Lytic murein transglycosylase
HMSLTHF_RS06965	ENOG4105DZ1	carboxypeptidase
HMSLTHF_RS06970	ENOG41084BA	UPF0250 protein
HMSLTHF_RS06975	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
HMSLTHF_RS06980	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
HMSLTHF_RS06995	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HMSLTHF_RS07020	ENOG4105EKQ	RNA-directed DNA polymerase
HMSLTHF_RS07025	ENOG4108PXI	ErfK YbiS YcfS YnhG
HMSLTHF_RS07030	ENOG4108JA2	transcriptioN-repair coupling factor
HMSLTHF_RS07040	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HMSLTHF_RS07045	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HMSLTHF_RS07050	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HMSLTHF_RS07060	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HMSLTHF_RS07065	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
HMSLTHF_RS07075	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
HMSLTHF_RS07100	ENOG4105C8T	Leucyl-tRNA synthetase
HMSLTHF_RS07115	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HMSLTHF_RS07125	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
HMSLTHF_RS07130	ENOG4105EYM	Major Facilitator superfamily
HMSLTHF_RS07135	ENOG4108YZY	peptidylprolyl cis-trans isomerase
HMSLTHF_RS07150	ENOG4105E4C	Lytic transglycosylase catalytic
HMSLTHF_RS07155	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
HMSLTHF_RS07170	ENOG4108JCI	Transcriptional regulator
HMSLTHF_RS07175	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
HMSLTHF_RS07180	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
HMSLTHF_RS07185	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
HMSLTHF_RS07190	ENOG4108Q3X	Transcriptional regulator
HMSLTHF_RS07195	ENOG4105E39	Enoyl-CoA hydratase
HMSLTHF_RS07205	ENOG4105E39	Enoyl-CoA hydratase
HMSLTHF_RS07215	ENOG4105E98	transcriptional regulator DeoR family
HMSLTHF_RS07220	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
HMSLTHF_RS07230	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
HMSLTHF_RS07255	ENOG4108IJ9	(ABC) transporter
HMSLTHF_RS07265	ENOG4107QPN	acyl-Coa dehydrogenase
HMSLTHF_RS07300	ENOG4105KST	dependent repressor
HMSLTHF_RS07315	ENOG4105CC5	ABC transporter
HMSLTHF_RS07345	ENOG4105CY2	Citrate transporter
HMSLTHF_RS07350	ENOG4105D3Y	Na H antiporter
HMSLTHF_RS07360	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
HMSLTHF_RS07365	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
HMSLTHF_RS07395	ENOG4105E27	serine threonine protein kinase
HMSLTHF_RS07405	ENOG4105EUJ	GTP cyclohydrolase i
HMSLTHF_RS07410	ENOG4105C26	Dehydrogenase
HMSLTHF_RS07415	ENOG4105DC1	bifunctional purine biosynthesis protein purh
HMSLTHF_RS07420	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
HMSLTHF_RS07425	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HMSLTHF_RS07430	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
HMSLTHF_RS07435	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HMSLTHF_RS07440	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
HMSLTHF_RS07445	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
HMSLTHF_RS07450	ENOG4105F0N	pyrophosphate phospho-hydrolase
HMSLTHF_RS07455	ENOG4108DT4	serine threonine protein kinase
HMSLTHF_RS07460	ENOG4105CTQ	phosphohexokinase
HMSLTHF_RS07465	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
HMSLTHF_RS07470	ENOG4105CDH	Citrulline--aspartate ligase
HMSLTHF_RS07480	ENOG4105BZU	Histidine kinase
HMSLTHF_RS07490	ENOG4108IRC	dna polymerase iii
HMSLTHF_RS07495	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HMSLTHF_RS07505	ENOG4105CSM	endonuclease III
HMSLTHF_RS07510	ENOG4105DZB	Electron transport complex
HMSLTHF_RS07520	ENOG4105D6A	Electron transport complex
HMSLTHF_RS07530	ENOG4108R3D	Electron transport complex
HMSLTHF_RS07535	ENOG4105DGN	Electron transport complex
HMSLTHF_RS07545	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
HMSLTHF_RS07560	ENOG4105DH7	May be involved in recombination (By similarity)
HMSLTHF_RS07565	ENOG4108TGP	Thioesterase superfamily protein
HMSLTHF_RS07570	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HMSLTHF_RS07575	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
HMSLTHF_RS07585	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
HMSLTHF_RS07595	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HMSLTHF_RS07605	ENOG4108DMH	HTH_ARAC
HMSLTHF_RS07620	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
HMSLTHF_RS07640	ENOG4107QHF	type ii secretion system protein e
HMSLTHF_RS07685	ENOG4105EWT	decarboxylase family
HMSLTHF_RS07700	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
HMSLTHF_RS07710	ENOG4105BZG	amino acid carrier protein
HMSLTHF_RS07715	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
HMSLTHF_RS07720	ENOG41063SB	peptidase
HMSLTHF_RS07730	ENOG4105GZI	Transcriptional regulator
HMSLTHF_RS07735	ENOG4105D6N	CoA-transferase, subunit a
HMSLTHF_RS07745	ENOG41090BQ	Glutaredoxin
HMSLTHF_RS07765	ENOG41065SU	Two-component system sensor kinase
HMSLTHF_RS07775	ENOG4105EKE	dihydroorotase
HMSLTHF_RS07780	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
HMSLTHF_RS07785	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
HMSLTHF_RS07825	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
HMSLTHF_RS07830	ENOG4105EYA	deoxyribonuclease
HMSLTHF_RS07835	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
HMSLTHF_RS07850	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
HMSLTHF_RS07860	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
HMSLTHF_RS07865	ENOG4107YNJ	LysR family Transcriptional regulator
HMSLTHF_RS07875	ENOG4107S2Z	UPF0761 membrane protein
HMSLTHF_RS07880	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
HMSLTHF_RS07885	ENOG4105C5I	Dehydrogenase
HMSLTHF_RS07895	ENOG4105C9M	aspartyl-trna synthetase
HMSLTHF_RS07900	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
HMSLTHF_RS07905	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
HMSLTHF_RS07910	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
HMSLTHF_RS07915	ENOG4107YD3	Thioesterase
HMSLTHF_RS07920	ENOG4105E02	MotA TolQ exbB proton channel
HMSLTHF_RS07925	ENOG4105M8F	Biopolymer transport protein exbD tolR
HMSLTHF_RS07935	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
HMSLTHF_RS07940	ENOG4105KCK	Peptidoglycan-associated lipoprotein
HMSLTHF_RS07950	ENOG4105UBK	short-chain dehydrogenase reductase
HMSLTHF_RS07955	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HMSLTHF_RS07960	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
HMSLTHF_RS07965	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
HMSLTHF_RS07985	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HMSLTHF_RS07995	ENOG41077A9	carbonic anhydrase
HMSLTHF_RS08000	ENOG4105DC8	reductase
HMSLTHF_RS08005	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
HMSLTHF_RS08010	ENOG4108JPW	Aminotransferase
HMSLTHF_RS08015	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
HMSLTHF_RS08025	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
HMSLTHF_RS08040	ENOG4105MYN	Zinc uptake regulation protein
HMSLTHF_RS08045	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
HMSLTHF_RS08050	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
HMSLTHF_RS08055	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
HMSLTHF_RS08060	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HMSLTHF_RS08070	ENOG4105C94	Transporter
HMSLTHF_RS08075	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
HMSLTHF_RS08080	ENOG4105C3R	Methionine synthase
HMSLTHF_RS08085	ENOG4107QI1	Mate efflux family protein
HMSLTHF_RS08090	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
HMSLTHF_RS08100	ENOG4108DG9	Smr protein MutS2
HMSLTHF_RS08110	ENOG4105CS1	NAD(P)H quinone oxidoreductase
HMSLTHF_RS08125	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
HMSLTHF_RS08130	ENOG4105CD5	CoA-binding domain protein
HMSLTHF_RS08145	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
HMSLTHF_RS08155	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
HMSLTHF_RS08165	ENOG4108MN8	Membrane
HMSLTHF_RS08175	ENOG4105EVH	UPF0753 protein
HMSLTHF_RS08180	ENOG4105D65	subunit l
HMSLTHF_RS08385	ENOG4106CVF	DNA replication protein
HMSLTHF_RS08405	ENOG4108XTP	Transcriptional regulator
HMSLTHF_RS08460	ENOG4108UUM	single-stranded DNA-binding protein
HMSLTHF_RS08510	ENOG4107Z6I	Thiamine biosynthesis protein
HMSLTHF_RS08515	ENOG4105EV9	Alpha Beta Hydrolase
HMSLTHF_RS08520	ENOG4105EX9	Membrane
HMSLTHF_RS08525	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HMSLTHF_RS08530	ENOG41080HT	Transcriptional regulator, arsr family
HMSLTHF_RS08535	ENOG4105ERU	peptidase
HMSLTHF_RS08545	ENOG4105E09	nadh pyrophosphatase
HMSLTHF_RS08550	ENOG4107RZZ	dna polymerase iii epsilon subunit
HMSLTHF_RS08555	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HMSLTHF_RS08565	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
HMSLTHF_RS08570	ENOG4105E9H	Lytic Murein transglycosylase
HMSLTHF_RS08580	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
HMSLTHF_RS08585	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
HMSLTHF_RS08590	ENOG4108JQ5	ABC transporter
HMSLTHF_RS08595	ENOG4105I08	Pseudouridine synthase
HMSLTHF_RS08605	ENOG4105FR1	rard protein
HMSLTHF_RS08615	ENOG4105CHH	sulfate transporter
HMSLTHF_RS08635	ENOG41060WC	Enoyl-CoA hydratase
HMSLTHF_RS08640	ENOG4105CC9	acyl-Coa dehydrogenase
HMSLTHF_RS08645	ENOG4105C1G	acyl-Coa dehydrogenase
HMSLTHF_RS08650	ENOG4105CGU	Enoyl-CoA hydratase
HMSLTHF_RS08665	ENOG4105BZJ	Electron transfer flavoprotein
HMSLTHF_RS08680	ENOG4105CEY	Amp-dependent synthetase and ligase
HMSLTHF_RS08685	ENOG4105C1G	acyl-Coa dehydrogenase
HMSLTHF_RS08690	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HMSLTHF_RS08695	ENOG4105CHU	acetyl-coa acetyltransferase
HMSLTHF_RS08700	ENOG4107HP6	Transcriptional regulator
HMSLTHF_RS08730	ENOG4107QSN	dihydrolipoamide acetyltransferase
HMSLTHF_RS08735	ENOG4105CPP	Dehydrogenase, E1 component
HMSLTHF_RS08740	ENOG4107R0V	Pyruvate dehydrogenase
HMSLTHF_RS08745	ENOG4105WJV	Binding-protein-dependent transport systems, inner membrane component
HMSLTHF_RS08750	ENOG4108IJ8	ABC transporter
HMSLTHF_RS08755	ENOG4107T5X	Binding-protein-dependent transport systems, inner membrane component
HMSLTHF_RS08765	ENOG4105C8N	cysteinyl-tRNA synthetase
HMSLTHF_RS08770	ENOG4105CX6	glutaminyL-tRNA synthetase
HMSLTHF_RS08775	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
HMSLTHF_RS08780	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
HMSLTHF_RS08785	ENOG4105EIN	peptidylprolyl cis-trans isomerase
HMSLTHF_RS08790	ENOG4105K70	DNA-binding protein
HMSLTHF_RS08795	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HMSLTHF_RS08800	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
HMSLTHF_RS08805	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HMSLTHF_RS08810	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
HMSLTHF_RS08820	ENOG4105QDK	Flavodoxin
HMSLTHF_RS08830	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HMSLTHF_RS08835	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
HMSLTHF_RS08840	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
HMSLTHF_RS08845	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
HMSLTHF_RS08850	ENOG41082NX	50s ribosomal protein l35
HMSLTHF_RS08855	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
HMSLTHF_RS08860	ENOG4105C22	threonyL-tRNA synthetase
HMSLTHF_RS08865	ENOG4105CDV	Ompa motb domain protein
HMSLTHF_RS08875	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
HMSLTHF_RS08895	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
HMSLTHF_RS08900	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
HMSLTHF_RS08935	ENOG4105CQ7	ATP-dependent helicase
HMSLTHF_RS08940	ENOG4108R86	Transcriptional regulator
HMSLTHF_RS08950	ENOG4105C7W	Xanthine dehydrogenase
HMSLTHF_RS08960	ENOG4107QUY	Guanine deaminase
HMSLTHF_RS08965	ENOG4105EKQ	RNA-directed DNA polymerase
HMSLTHF_RS08995	ENOG4105CA0	peroxidase
HMSLTHF_RS09000	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
HMSLTHF_RS09005	ENOG4108JJ8	(ABC) transporter
HMSLTHF_RS09010	ENOG4108JJ9	ABC, transporter
HMSLTHF_RS09015	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
HMSLTHF_RS09020	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HMSLTHF_RS09030	ENOG4105F1S	paraquat-inducible protein a
HMSLTHF_RS09035	ENOG4105DY2	Paraquat-inducible protein b
HMSLTHF_RS09040	ENOG4108Q2G	(LipO)protein
HMSLTHF_RS09045	ENOG4105C1J	atp-dependent rna helicase
HMSLTHF_RS09055	ENOG4105DJ2	Major Facilitator Superfamily
HMSLTHF_RS09060	ENOG4105HDK	L-asparaginase
HMSLTHF_RS09080	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
HMSLTHF_RS09085	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
HMSLTHF_RS09105	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
HMSLTHF_RS09110	ENOG4107QIJ	Aconitate hydratase 2
HMSLTHF_RS09115	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
HMSLTHF_RS09120	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
HMSLTHF_RS09125	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HMSLTHF_RS09135	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
HMSLTHF_RS09140	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
HMSLTHF_RS09150	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
HMSLTHF_RS09155	ENOG4105U5Y	Transcriptional regulator
HMSLTHF_RS09160	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
HMSLTHF_RS09180	ENOG4108ZAF	Molybdopterin
HMSLTHF_RS09185	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HMSLTHF_RS09190	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
HMSLTHF_RS09195	ENOG4105C2W	permease
HMSLTHF_RS09200	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
HMSLTHF_RS09205	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
HMSLTHF_RS09210	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
HMSLTHF_RS09215	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
HMSLTHF_RS09220	ENOG4105C7N	Xanthine uracil vitamin C permease
HMSLTHF_RS09225	ENOG4108R6K	riboflavin synthase, subunit alpha
HMSLTHF_RS09230	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
HMSLTHF_RS09235	ENOG4108UMI	ABC transporter, permease
HMSLTHF_RS09240	ENOG4105D01	(LipO)protein
HMSLTHF_RS09245	ENOG4108ZGC	gaf domain protein
HMSLTHF_RS09265	ENOG4105C9Q	fumarate hydratase class II
HMSLTHF_RS09275	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
HMSLTHF_RS09280	ENOG4105C02	permease
HMSLTHF_RS09285	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
HMSLTHF_RS09290	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
HMSLTHF_RS09295	ENOG4105DHP	deoxycytidine triphosphate deaminase
HMSLTHF_RS09310	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HMSLTHF_RS09315	ENOG4105BZU	Histidine kinase
HMSLTHF_RS09320	ENOG41090A4	Pterin carbinolamine dehydratase
HMSLTHF_RS09325	ENOG4105CGF	Aromatic amino acid aminotransferase
HMSLTHF_RS09340	ENOG4108YYC	ycei family
HMSLTHF_RS09345	ENOG4105DS1	cytochrome b561
HMSLTHF_RS09355	ENOG4105C28	cystathionine
HMSLTHF_RS09360	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
HMSLTHF_RS09375	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HMSLTHF_RS09380	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
HMSLTHF_RS09385	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
HMSLTHF_RS09395	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
HMSLTHF_RS09410	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HMSLTHF_RS09415	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HMSLTHF_RS09420	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HMSLTHF_RS09425	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HMSLTHF_RS09430	ENOG4108MP6	LysR family Transcriptional regulator
HMSLTHF_RS09435	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
HMSLTHF_RS09440	ENOG4108TGY	Glutathione S-transferase
HMSLTHF_RS09445	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HMSLTHF_RS09450	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HMSLTHF_RS09455	ENOG4105C1G	acyl-Coa dehydrogenase
HMSLTHF_RS09465	ENOG4105C32	Amino acid ABC transporter (Permease)
HMSLTHF_RS09475	ENOG4108IV0	ABC, transporter
HMSLTHF_RS09480	ENOG4105C0Z	ABC transporter
HMSLTHF_RS09490	ENOG4105C1G	acyl-Coa dehydrogenase
HMSLTHF_RS09495	ENOG4107QX3	carboxylase
HMSLTHF_RS09500	ENOG4108IPT	Naphthoate synthase
HMSLTHF_RS09510	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
HMSLTHF_RS09515	ENOG4105CEY	Amp-dependent synthetase and ligase
HMSLTHF_RS09520	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HMSLTHF_RS09530	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
HMSLTHF_RS09550	ENOG4105FE9	pseudouridine synthase
HMSLTHF_RS09560	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
HMSLTHF_RS09565	ENOG4105DXN	mazG family
HMSLTHF_RS09570	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HMSLTHF_RS09575	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
HMSLTHF_RS09580	ENOG4105C6T	cysteine synthase
HMSLTHF_RS09585	ENOG4105BZU	Histidine kinase
HMSLTHF_RS09590	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
HMSLTHF_RS09600	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
HMSLTHF_RS09605	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
HMSLTHF_RS09610	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
HMSLTHF_RS09615	ENOG4105C3F	Signal peptidase i
HMSLTHF_RS09620	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
HMSLTHF_RS09625	ENOG4105C0H	protease
HMSLTHF_RS09635	ENOG4105VQK	sigma E regulatory protein, MucB RseB
HMSLTHF_RS09640	ENOG41069E1	anti sigma-E protein RseA
HMSLTHF_RS09645	ENOG4105EMN	RNA polymerase sigma factor
HMSLTHF_RS09650	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HMSLTHF_RS09655	ENOG4105DVT	helicase
HMSLTHF_RS09670	ENOG4105CGK	Exodeoxyribonuclease III
HMSLTHF_RS09685	ENOG4109015	Biopolymer transport protein exbD tolR
HMSLTHF_RS09715	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HMSLTHF_RS09720	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
HMSLTHF_RS09735	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HMSLTHF_RS09740	ENOG4105C10	Electron transfer flavoprotein
HMSLTHF_RS09745	ENOG4105BZJ	Electron transfer flavoprotein
HMSLTHF_RS09750	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
HMSLTHF_RS09755	ENOG4105ENA	helicase
HMSLTHF_RS09765	ENOG4105F8V	Hydrolase, tatD family
HMSLTHF_RS09775	ENOG4107QRG	dna polymerase iii
HMSLTHF_RS09780	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
HMSLTHF_RS09785	ENOG4105HHA	aminodeoxychorismate lyase
HMSLTHF_RS09790	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
HMSLTHF_RS09795	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HMSLTHF_RS09800	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HMSLTHF_RS09805	ENOG4105CHR	reductase
HMSLTHF_RS09810	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
HMSLTHF_RS09815	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
HMSLTHF_RS09820	ENOG4105VGS	50s ribosomal protein l32
HMSLTHF_RS09825	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
HMSLTHF_RS09830	ENOG4108UHJ	MAF-like protein
HMSLTHF_RS09840	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HMSLTHF_RS09845	ENOG4105EI2	Pseudouridine synthase
HMSLTHF_RS09850	ENOG4107QQB	Ribonuclease E
HMSLTHF_RS09855	ENOG4105D4A	Cell wall formation (By similarity)
HMSLTHF_RS09865	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
HMSLTHF_RS09870	ENOG4105W49	UPF0434 protein
HMSLTHF_RS09875	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
HMSLTHF_RS09880	ENOG4105BZ1	(ABC) transporter
HMSLTHF_RS09895	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HMSLTHF_RS09900	ENOG4105D60	lipoprotein releasing system transmembrane protein
HMSLTHF_RS09905	ENOG4105DWY	Agmatine deiminase
HMSLTHF_RS09915	ENOG4108UB3	Thiamine monophosphate
HMSLTHF_RS09920	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
HMSLTHF_RS09925	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
HMSLTHF_RS09935	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HMSLTHF_RS09940	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
HMSLTHF_RS09945	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
HMSLTHF_RS09950	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
HMSLTHF_RS09955	ENOG4105CPF	Cell wall formation (By similarity)
HMSLTHF_RS09960	ENOG4105DFU	Cell wall formation (By similarity)
HMSLTHF_RS09965	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
HMSLTHF_RS09970	ENOG4105CNI	cell division protein FtsW
HMSLTHF_RS09975	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
HMSLTHF_RS09980	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
HMSLTHF_RS09985	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
HMSLTHF_RS09990	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
HMSLTHF_RS09995	ENOG4105CJN	penicillin-binding protein
HMSLTHF_RS10000	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
HMSLTHF_RS10005	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
HMSLTHF_RS10015	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
HMSLTHF_RS10020	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
HMSLTHF_RS10030	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
HMSLTHF_RS10035	ENOG4105W4M	Transport-associated protein
HMSLTHF_RS10040	ENOG4105KB2	stringent starvation protein b
HMSLTHF_RS10045	ENOG4107MKT	Stringent starvation protein a
HMSLTHF_RS10050	ENOG4105EIX	cytochrome c1
HMSLTHF_RS10055	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
HMSLTHF_RS10060	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
HMSLTHF_RS10065	ENOG4108UJD	30S ribosomal protein S9
HMSLTHF_RS10070	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
HMSLTHF_RS10075	ENOG4105D6Z	AFG1 family ATPase
HMSLTHF_RS10080	ENOG4108W2Q	Cytochrome d ubiquinol oxidase subunit III
HMSLTHF_RS10085	ENOG4107QNR	UPF0135 protein
HMSLTHF_RS10090	ENOG4105C0H	protease
HMSLTHF_RS10095	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
HMSLTHF_RS10100	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
HMSLTHF_RS10105	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HMSLTHF_RS10110	ENOG4105VFK	BolA family
HMSLTHF_RS10125	ENOG4107PE3	Mammalian cell entry related domain protein
HMSLTHF_RS10130	ENOG4105CY3	ABC transporter, permease
HMSLTHF_RS10135	ENOG4105DHJ	ABC, transporter
HMSLTHF_RS10140	ENOG4105C2X	Arabinose 5-phosphate isomerase
HMSLTHF_RS10160	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
HMSLTHF_RS10165	ENOG4108IUZ	ABC transporter
HMSLTHF_RS10170	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HMSLTHF_RS10175	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
HMSLTHF_RS10180	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
HMSLTHF_RS10185	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
HMSLTHF_RS10195	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
HMSLTHF_RS10200	ENOG4105N42	UPF0307 protein
HMSLTHF_RS10205	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
HMSLTHF_RS10215	ENOG4105C03	ribonuclease
HMSLTHF_RS10220	ENOG4108Z03	MAF-like protein
HMSLTHF_RS10230	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
HMSLTHF_RS10240	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HMSLTHF_RS10245	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HMSLTHF_RS10250	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HMSLTHF_RS10255	ENOG4108BY2	phosphohistidine phosphatase
HMSLTHF_RS10260	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
HMSLTHF_RS10265	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
HMSLTHF_RS10275	ENOG4107SC1	transglycosylase
HMSLTHF_RS10280	ENOG410829K	Lysine exporter protein (Lyse ygga)
HMSLTHF_RS10285	ENOG4105W1Y	Transcriptional regulator
HMSLTHF_RS10300	ENOG4105W1Y	Transcriptional regulator
HMSLTHF_RS10350	ENOG4105EKQ	RNA-directed DNA polymerase
HMSLTHF_RS10395	ENOG4105VEQ	Cold shock protein
HMSLTHF_RS10405	ENOG4107TE5	Lipid kinase
HMSLTHF_RS10410	ENOG4105CD8	aminopeptidase N
HMSLTHF_RS10415	ENOG4108VPT	UPF0234 protein
HMSLTHF_RS10420	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
HMSLTHF_RS10425	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
HMSLTHF_RS10430	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
HMSLTHF_RS10435	ENOG4105EPW	hflc protein
HMSLTHF_RS10440	ENOG4107QJR	hflk protein
HMSLTHF_RS10445	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HMSLTHF_RS10450	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
HMSLTHF_RS10455	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
HMSLTHF_RS10460	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
HMSLTHF_RS10465	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HMSLTHF_RS10470	ENOG4105K8N	protein family UPF0079, ATPase
HMSLTHF_RS10475	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
HMSLTHF_RS10480	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
HMSLTHF_RS10485	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
HMSLTHF_RS10490	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
HMSLTHF_RS10495	ENOG4105KHC	sulfurtransferase
HMSLTHF_RS10500	ENOG4105DJ4	phosphatidylserine decarboxylase
HMSLTHF_RS10505	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
HMSLTHF_RS10510	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HMSLTHF_RS10515	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
HMSLTHF_RS10525	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
HMSLTHF_RS10540	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
HMSLTHF_RS10550	ENOG4105D65	subunit l
HMSLTHF_RS10555	ENOG4108ZE9	Monovalent cation H antiporter subunit C
HMSLTHF_RS10560	ENOG4107R4Z	monovalent cation h antiporter subunit d
HMSLTHF_RS10565	ENOG4105SC1	monovalent cation H antiporter subunit E
HMSLTHF_RS10570	ENOG4105W4C	monovalent cation H antiporter subunit F
HMSLTHF_RS10575	ENOG4105KJM	monovalent cation h antiporter subunit g
HMSLTHF_RS10585	ENOG4105EAC	phosphoserine phosphatase
HMSLTHF_RS10590	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HMSLTHF_RS10595	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HMSLTHF_RS10600	ENOG4107QP8	phosphohexose isomerase
HMSLTHF_RS10605	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
HMSLTHF_RS10610	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
HMSLTHF_RS10625	ENOG4108Z0Z	intracellular protease Pfpi family
HMSLTHF_RS10630	ENOG4105HD0	Transcriptional regulator of molybdate metabolism, LysR family
HMSLTHF_RS10650	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
HMSLTHF_RS10655	ENOG4105C11	sulfate adenylyltransferase), subunit 2
HMSLTHF_RS10660	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
HMSLTHF_RS10665	ENOG4108SX3	cytoplasmic protein
HMSLTHF_RS10670	ENOG41087AY	ADP-Ribose pyrophosphatase
HMSLTHF_RS10680	ENOG4108RRZ	Transcription elongation factor GreB
HMSLTHF_RS10685	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
HMSLTHF_RS10690	ENOG4106371	Methyltransferase
HMSLTHF_RS10695	ENOG4105BZU	Histidine kinase
HMSLTHF_RS10720	ENOG4105BZU	Histidine kinase
HMSLTHF_RS10725	ENOG4105BZU	Histidine kinase
HMSLTHF_RS10740	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
HMSLTHF_RS10745	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
HMSLTHF_RS10755	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
HMSLTHF_RS10765	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
HMSLTHF_RS10770	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
HMSLTHF_RS10775	ENOG4105HF0	Membrane
HMSLTHF_RS10780	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HMSLTHF_RS10790	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
HMSLTHF_RS10805	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
HMSLTHF_RS10820	ENOG4105PBF	Anti-RNA polymerase sigma 70 factor
HMSLTHF_RS10825	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
HMSLTHF_RS10830	ENOG4105D9M	gamma-glutamylcysteine synthetase
HMSLTHF_RS10835	ENOG4105BZM	domain protein
HMSLTHF_RS10850	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
HMSLTHF_RS10855	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
HMSLTHF_RS10860	ENOG4105VEJ	Heat shock protein
HMSLTHF_RS10865	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
HMSLTHF_RS10870	ENOG4107RK2	ADP-ribose diphosphatase NudE
HMSLTHF_RS10875	ENOG4105D9R	oxidoreductase
HMSLTHF_RS10880	ENOG4105C01	Dihydroxy-acid dehydratase
HMSLTHF_RS10885	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
HMSLTHF_RS10885	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
HMSLTHF_RS10890	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HMSLTHF_RS10900	ENOG4108ZAI	phosphatidylglycerophosphatase a
HMSLTHF_RS10905	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
HMSLTHF_RS10910	ENOG4107YIM	Involved in the transcription termination process (By similarity)
HMSLTHF_RS10915	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
HMSLTHF_RS10920	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
HMSLTHF_RS10925	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
HMSLTHF_RS10930	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
HMSLTHF_RS10935	ENOG4107QW3	Sucrose phosphorylase
HMSLTHF_RS10940	ENOG4107ZT5	Thiol disulfide interchange protein
HMSLTHF_RS10945	ENOG4108KHN	disulfide isomerase, thiol-disulfide oxidase
HMSLTHF_RS10975	ENOG4105EQR	Transposase IS116 IS110 IS902
HMSLTHF_RS10995	ENOG4105KFG	YeeE YedE family protein
HMSLTHF_RS11015	ENOG4105C8Q	Methyl-accepting chemotaxis
HMSLTHF_RS11020	ENOG4105D7V	transposase
HMSLTHF_RS11025	ENOG4105C3Q	Glycosyl transferase, family 2
HMSLTHF_RS11030	ENOG4108ZFX	Mannosyl-3-phosphoglycerate phosphatase
HMSLTHF_RS11035	ENOG4108ZG0	Ompa motb domain protein
HMSLTHF_RS11050	ENOG4108ST3	glycosyltransferase
HMSLTHF_RS11055	ENOG4105PF3	O-Antigen polymerase
HMSLTHF_RS11060	ENOG4105CY0	Metallo-Beta-Lactamase
HMSLTHF_RS11075	ENOG4105RVE	Uncharacterized protein conserved in bacteria (DUF2136)
HMSLTHF_RS11080	ENOG4108Z3N	Transcriptional regulator
HMSLTHF_RS11110	ENOG4108KQJ	Type 11 methyltransferase
HMSLTHF_RS11115	ENOG4105EY8	ABC transporter
HMSLTHF_RS11125	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HMSLTHF_RS11130	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HMSLTHF_RS11140	ENOG4105D3Q	Sugar transferase
HMSLTHF_RS11155	ENOG4108JJ6	Type I secretion system ATPase
HMSLTHF_RS11165	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
HMSLTHF_RS11175	ENOG4105CV6	ABC transporter, permease
HMSLTHF_RS11180	ENOG4108I0Y	(ABC) transporter
HMSLTHF_RS11185	ENOG4108UJV	acyl-CoA thioesterase i
HMSLTHF_RS11190	ENOG4105VUH	addiction module killer protein
HMSLTHF_RS11195	ENOG4105YES	addiction module antidote protein
HMSLTHF_RS11215	ENOG4105BZU	Histidine kinase
HMSLTHF_RS11225	ENOG4105C5H	ABC transporter
HMSLTHF_RS11230	ENOG4105K59	histidine triad (HIT) protein
HMSLTHF_RS11235	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
HMSLTHF_RS11245	ENOG4105C12	Phosphoribosylglycinamide synthetase
HMSLTHF_RS11250	ENOG4108NVM	synthesis repressor PhaR
HMSLTHF_RS11265	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
HMSLTHF_RS11270	ENOG4105CVE	Lytic murein transglycosylase
HMSLTHF_RS11275	ENOG4105KJM	monovalent cation h antiporter subunit g
HMSLTHF_RS11280	ENOG41080TA	Multiple resistance and ph regulation protein f
HMSLTHF_RS11285	ENOG4105SC1	monovalent cation H antiporter subunit E
HMSLTHF_RS11290	ENOG4108JPZ	Monovalent cation H antiporter subunit D
HMSLTHF_RS11295	ENOG4105MKQ	Monovalent cation H antiporter subunit C
HMSLTHF_RS11300	ENOG4105GND	monovalent cation H antiporter subunit B
HMSLTHF_RS11305	ENOG4105D65	subunit l
HMSLTHF_RS11310	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
HMSLTHF_RS11335	ENOG4105CDU	Replicative dna helicase
HMSLTHF_RS11340	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
HMSLTHF_RS11350	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
HMSLTHF_RS11355	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
HMSLTHF_RS11360	ENOG4105C2N	RNA methyltransferase TrmH family group 3
HMSLTHF_RS11365	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
HMSLTHF_RS11400	ENOG4105ED1	spovr family
HMSLTHF_RS11405	ENOG4106AKX	UPF0229 protein
HMSLTHF_RS11410	ENOG4105CYN	Serine protein kinase
HMSLTHF_RS11420	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HMSLTHF_RS11425	ENOG4108IPJ	Membrane
HMSLTHF_RS11430	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
HMSLTHF_RS11440	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
HMSLTHF_RS11445	ENOG4105BZG	amino acid carrier protein
HMSLTHF_RS11470	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
HMSLTHF_RS11475	ENOG4105D7V	transposase
HMSLTHF_RS11485	ENOG4105EJC	lysr family transcriptional regulator
HMSLTHF_RS11490	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HMSLTHF_RS11495	ENOG4105D7V	transposase
HMSLTHF_RS11500	ENOG4105CS1	NAD(P)H quinone oxidoreductase
HMSLTHF_RS11510	ENOG4108JEH	abc transporter atp-binding protein
HMSLTHF_RS11515	ENOG4105DSP	amino acid AbC transporter
HMSLTHF_RS11520	ENOG4106YG3	ABC transporter
HMSLTHF_RS11525	ENOG4107R0W	ABC transporter
HMSLTHF_RS11540	ENOG4105BZU	Histidine kinase
HMSLTHF_RS11545	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
HMSLTHF_RS11550	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
HMSLTHF_RS11560	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
HMSLTHF_RS11565	ENOG4106WHD	Tetrathionate reductase
HMSLTHF_RS11570	ENOG4105DB1	molybdopterin oxidoreductase
HMSLTHF_RS11580	ENOG4105C01	Dihydroxy-acid dehydratase
HMSLTHF_RS11590	ENOG4105MRD	Phage derived protein Gp49-like (DUF891)
HMSLTHF_RS11595	ENOG4105DSY	exodeoxyribonuclease V, gamma
HMSLTHF_RS11600	ENOG4107RH7	Nicotinate phosphoribosyltransferase
HMSLTHF_RS11605	ENOG4107QKA	exodeoxyribonuclease V beta
HMSLTHF_RS11610	ENOG4107QYX	exodeoxyribonuclease v alpha
HMSLTHF_RS11635	ENOG4105EQR	Transposase IS116 IS110 IS902
HMSLTHF_RS11650	ENOG4105EJC	lysr family transcriptional regulator
HMSLTHF_RS11655	ENOG4105EMU	Dehydrogenase
HMSLTHF_RS11695	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
HMSLTHF_RS11700	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
HMSLTHF_RS11705	ENOG4108MGI	Transcriptional regulator
HMSLTHF_RS11725	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
HMSLTHF_RS11740	ENOG4105BZU	Histidine kinase
HMSLTHF_RS11760	ENOG4105S64	Formate nitrite transporter
HMSLTHF_RS11765	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
HMSLTHF_RS11775	ENOG4105DQ4	alcohol dehydrogenase
HMSLTHF_RS11780	ENOG4105CF7	AraC family transcriptional regulator
HMSLTHF_RS11790	ENOG4105DUM	transcriptional regulator, lysR family
HMSLTHF_RS11795	ENOG4105DWT	malate dehydrogenase (quinone)
HMSLTHF_RS11800	ENOG4105VRT	cytoplasmic protein
HMSLTHF_RS11820	ENOG4107R7Y	intracellular protease Pfpi family
HMSLTHF_RS11830	ENOG4105C8Q	Methyl-accepting chemotaxis
HMSLTHF_RS11840	ENOG4107XC4	flavin reductase domain protein, FMN-binding
HMSLTHF_RS11845	ENOG4108YZN	class I peptide chain release factor
HMSLTHF_RS11855	ENOG4105CTU	Proline racemase
HMSLTHF_RS11860	ENOG4105CPQ	Dehydrogenase
HMSLTHF_RS11870	ENOG4105D7N	magnesium and cobalt transport protein CorA
HMSLTHF_RS11875	ENOG4105BZU	Histidine kinase
HMSLTHF_RS11895	ENOG4105C26	Dehydrogenase
HMSLTHF_RS11930	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HMSLTHF_RS11940	ENOG41062YB	Trap dicarboxylate transporter, dctp subunit
HMSLTHF_RS11955	ENOG4105EN6	Membrane
HMSLTHF_RS11995	ENOG4105EY2	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity)
HMSLTHF_RS12000	ENOG4105C26	Dehydrogenase
HMSLTHF_RS12010	ENOG4105F4X	arginine
HMSLTHF_RS12015	ENOG4105C8Y	Acetylornithine aminotransferase
HMSLTHF_RS12020	ENOG4105ECQ	AraC Family Transcriptional Regulator
HMSLTHF_RS12030	ENOG4105RKW	reductase (By
HMSLTHF_RS12050	ENOG4105CDY	transcriptional regulatory protein
HMSLTHF_RS12070	ENOG4105CB2	alcohol dehydrogenase
HMSLTHF_RS12075	ENOG4105BZ1	(ABC) transporter
HMSLTHF_RS12090	ENOG4105C1J	atp-dependent rna helicase
HMSLTHF_RS12095	ENOG4108Z66	YbaK ebsC protein
HMSLTHF_RS12105	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HMSLTHF_RS12115	ENOG4108X4D	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
HMSLTHF_RS12125	ENOG4105DRS	transport system, permease
HMSLTHF_RS12145	ENOG4108IJ9	(ABC) transporter
HMSLTHF_RS12160	ENOG4105E5H	Transposase
HMSLTHF_RS12175	ENOG4105ETE	Transcriptional regulator (LacI family
HMSLTHF_RS12190	ENOG4105C5Q	Transcriptional regulator
HMSLTHF_RS12195	ENOG4108IAB	Phoh family
HMSLTHF_RS12200	ENOG4107U9T	Pfam:Ribonuclease_BN
HMSLTHF_RS12205	ENOG4105C8S	subunit m
HMSLTHF_RS12210	ENOG4108JPZ	Monovalent cation H antiporter subunit D
HMSLTHF_RS12215	ENOG4108JPZ	Monovalent cation H antiporter subunit D
HMSLTHF_RS12235	ENOG4105EKQ	RNA-directed DNA polymerase
HMSLTHF_RS12240	ENOG4105VEQ	Cold shock protein
HMSLTHF_RS12250	ENOG4105C26	Dehydrogenase
HMSLTHF_RS12255	ENOG4105DUM	transcriptional regulator, lysR family
HMSLTHF_RS12265	ENOG4105C26	Dehydrogenase
HMSLTHF_RS12270	ENOG4108JUB	Transcriptional regulator
HMSLTHF_RS12280	ENOG4105C0A	alcohol dehydrogenase
HMSLTHF_RS12285	ENOG4105C26	Dehydrogenase
HMSLTHF_RS12290	ENOG4108ZAI	phosphatidylglycerophosphatase a
HMSLTHF_RS12300	ENOG4105EYH	Exonuclease
HMSLTHF_RS12305	ENOG4107RFY	SbcCD D subunit
HMSLTHF_RS12310	ENOG4105C8P	)-transporter
HMSLTHF_RS12320	ENOG4108IYC	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
HMSLTHF_RS12345	ENOG4105E0K	tonB-dependent siderophore receptor
HMSLTHF_RS12350	ENOG4105D82	Glutamate dehydrogenase
HMSLTHF_RS12355	ENOG4105NXH	GreA GreB family elongation factor
HMSLTHF_RS12360	ENOG4105BZU	Histidine kinase
HMSLTHF_RS12365	ENOG4105W2W	Cytotoxic translational repressor of toxin-antitoxin stability system
HMSLTHF_RS12420	ENOG4105DZR	Type I site-specific deoxyribonuclease
HMSLTHF_RS12440	ENOG4105EKX	Restriction modification system DNA (Specificity
HMSLTHF_RS12445	ENOG4105CVR	type I restriction-modification system
HMSLTHF_RS12515	ENOG4105BZ1	(ABC) transporter
HMSLTHF_RS12520	ENOG4105E0A	ABC, transporter
HMSLTHF_RS12525	ENOG4105TVJ	transport system, permease
HMSLTHF_RS12530	ENOG4105DQ5	transport system permease protein
HMSLTHF_RS12540	ENOG4105D05	Receptor
HMSLTHF_RS12550	ENOG4105D05	Receptor
HMSLTHF_RS12555	ENOG4108R4R	Iron-regulated virulence regulatory protein
HMSLTHF_RS12575	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HMSLTHF_RS12590	ENOG4108IJ7	Glycine betaine
HMSLTHF_RS12595	ENOG4107SQ8	Glycine betaine
HMSLTHF_RS12605	ENOG4105C94	Transporter
HMSLTHF_RS12640	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
HMSLTHF_RS12660	ENOG4105CC0	LysR family Transcriptional regulator
HMSLTHF_RS12665	ENOG4105EJQ	L-serine dehydratase
HMSLTHF_RS12685	ENOG4105CFC	Transporter
HMSLTHF_RS12690	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HMSLTHF_RS12695	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
HMSLTHF_RS12700	ENOG4105VCC	30S ribosomal protein S21
HMSLTHF_RS12705	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HMSLTHF_RS12710	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
HMSLTHF_RS12725	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HMSLTHF_RS12730	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
HMSLTHF_RS12735	ENOG4105NWN	ApaG protein
HMSLTHF_RS12740	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
HMSLTHF_RS12745	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
HMSLTHF_RS12750	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
HMSLTHF_RS12755	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
HMSLTHF_RS12760	ENOG4105EHM	Aminoglycoside phosphotransferase
HMSLTHF_RS12765	ENOG4108S0S	Nucleotidyl transferase
HMSLTHF_RS12770	ENOG4108UKZ	OsmC family
HMSLTHF_RS12775	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
HMSLTHF_RS12780	ENOG4105D1S	lipid A biosynthesis
HMSLTHF_RS12785	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HMSLTHF_RS12790	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HMSLTHF_RS12795	ENOG4108K5P	(LipO)protein
HMSLTHF_RS12805	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
HMSLTHF_RS12810	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
HMSLTHF_RS12815	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
HMSLTHF_RS12820	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
HMSLTHF_RS12825	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
HMSLTHF_RS12830	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
HMSLTHF_RS12840	ENOG4107RGH	Aldehyde dehydrogenase
HMSLTHF_RS12845	ENOG4105BZU	Histidine kinase
HMSLTHF_RS12855	ENOG4106KNT	transcriptional regulator
HMSLTHF_RS12865	ENOG4105EW9	transcriptional regulator AsnC family
HMSLTHF_RS12870	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
HMSLTHF_RS12880	ENOG4105WMR	Protein CrcB homolog
HMSLTHF_RS12885	ENOG4105WMR	Protein CrcB homolog
HMSLTHF_RS12890	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
HMSLTHF_RS12900	ENOG4105CHH	sulfate transporter
HMSLTHF_RS12905	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HMSLTHF_RS12920	ENOG4105D3R	alkyl hydroperoxide reductase
HMSLTHF_RS12945	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
HMSLTHF_RS12960	ENOG4105EKQ	RNA-directed DNA polymerase
HMSLTHF_RS12965	ENOG4105C8Y	Acetylornithine aminotransferase
HMSLTHF_RS12970	ENOG4105C26	Dehydrogenase
HMSLTHF_RS12975	ENOG4108RYR	transcriptional regulator AsnC family
HMSLTHF_RS12980	ENOG4105E5N	succinylglutamate desuccinylase aspartoacylase
HMSLTHF_RS12985	ENOG4105ENR	peptidase, M24
HMSLTHF_RS12990	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
HMSLTHF_RS13000	ENOG4105DWU	Membrane
HMSLTHF_RS13010	ENOG4105DDY	UPF0142 protein ycaO
HMSLTHF_RS13020	ENOG4105CR8	Transcriptional regulator
HMSLTHF_RS13035	ENOG4108WUH	Transcriptional regulator, TetR family
HMSLTHF_RS13050	ENOG4105EB3	Histidine kinase
HMSLTHF_RS13055	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
HMSLTHF_RS13070	ENOG4108VSE	mercuric transport protein
HMSLTHF_RS13075	ENOG4105XIV	Mercuric transport protein, periplasmic component
HMSLTHF_RS13145	ENOG4108C33	Resolvase
HMSLTHF_RS13165	ENOG4105C94	Transporter
HMSLTHF_RS13175	ENOG4105C26	Dehydrogenase
HMSLTHF_RS13185	ENOG4105BZU	Histidine kinase
HMSLTHF_RS13195	ENOG4105BZU	Histidine kinase
HMSLTHF_RS13225	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HMSLTHF_RS13235	ENOG4105GQU	Trap dicarboxylate transporter, dctp subunit
HMSLTHF_RS13245	ENOG4108594	Permease of the drug metabolite transporter
HMSLTHF_RS13255	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HMSLTHF_RS13260	ENOG4105E0C	molybdate abc transporter
HMSLTHF_RS13265	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
HMSLTHF_RS13270	ENOG4105CA9	Pyruvate kinase
HMSLTHF_RS13275	ENOG4108Z2U	ureidoglycolate hydrolase
HMSLTHF_RS13280	ENOG4105S0E	allantoin catabolism protein
HMSLTHF_RS13290	ENOG410633P	Hydantoin racemase
HMSLTHF_RS13300	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
HMSLTHF_RS13320	ENOG4105FFA	Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin (By similarity)
HMSLTHF_RS13340	ENOG4105CYM	Glutathione S-transferase
HMSLTHF_RS13350	ENOG4105DAA	L-lactate
HMSLTHF_RS13355	ENOG4105CQB	FAD linked oxidase domain protein
HMSLTHF_RS13360	ENOG4105EU8	FAD linked oxidase domain protein
HMSLTHF_RS13365	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
HMSLTHF_RS13370	ENOG4108ZJF	Glcg protein
HMSLTHF_RS13405	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
HMSLTHF_RS13420	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
HMSLTHF_RS13425	ENOG4105C58	cytochrome c oxidase accessory protein ccog
HMSLTHF_RS13435	ENOG4105C59	p-type ATPase
HMSLTHF_RS13450	ENOG4105D4P	Coproporphyrinogen iii oxidase
HMSLTHF_RS13460	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
HMSLTHF_RS13480	ENOG4107QN1	sodium solute
HMSLTHF_RS13490	ENOG4105BZU	Histidine kinase
HMSLTHF_RS13500	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HMSLTHF_RS13520	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
HMSLTHF_RS13525	ENOG41072GX	Peptidase M22 Glycoprotease
HMSLTHF_RS13530	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
HMSLTHF_RS13535	ENOG4107QSN	dihydrolipoamide acetyltransferase
HMSLTHF_RS13540	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
HMSLTHF_RS13545	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
HMSLTHF_RS13550	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
HMSLTHF_RS13560	ENOG4108R96	Methyltransferase, YaeB family
HMSLTHF_RS13565	ENOG4105C8V	SAICAR synthetase
HMSLTHF_RS13575	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HMSLTHF_RS13580	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HMSLTHF_RS13590	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
HMSLTHF_RS13595	ENOG4105ERG	peptidase m48, ste24p
HMSLTHF_RS13600	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
HMSLTHF_RS13615	ENOG4105FE9	pseudouridine synthase
HMSLTHF_RS13620	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
HMSLTHF_RS13625	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
HMSLTHF_RS13630	ENOG4105CFI	type iii restriction protein res subunit
HMSLTHF_RS13635	ENOG4108ETH	Formylglycinamide ribotide synthetase
HMSLTHF_RS13640	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
HMSLTHF_RS13645	ENOG4108Z6B	deaminase
HMSLTHF_RS13650	ENOG4105C29	acyl-CoA thioesterase
HMSLTHF_RS13655	ENOG4105C6K	Malic enzyme
HMSLTHF_RS13660	ENOG4105VFB	Binds the 23S rRNA (By similarity)
HMSLTHF_RS13665	ENOG4105C25	Primosomal protein n'
HMSLTHF_RS13670	ENOG4105C75	arginyL-tRNA synthetase
HMSLTHF_RS13680	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
HMSLTHF_RS13685	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
HMSLTHF_RS13695	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HMSLTHF_RS13705	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
HMSLTHF_RS13710	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
HMSLTHF_RS13715	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
HMSLTHF_RS13720	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
HMSLTHF_RS13730	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
HMSLTHF_RS13735	ENOG4105D52	delta-aminolevulinic acid dehydratase
HMSLTHF_RS13745	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
HMSLTHF_RS13750	ENOG4105DZ2	Transcriptional regulator
HMSLTHF_RS13755	ENOG4105JJR	Histidine kinase
HMSLTHF_RS13760	ENOG4107EXC	regulatoR
HMSLTHF_RS13775	ENOG4108WIW	Aspartyl protease
HMSLTHF_RS13810	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
HMSLTHF_RS13815	ENOG41080IJ	Diacylglycerol kinase
HMSLTHF_RS13820	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
HMSLTHF_RS13825	ENOG410814C	multidrug resistance protein
HMSLTHF_RS13835	ENOG4107RX2	synthase
HMSLTHF_RS13840	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
HMSLTHF_RS13845	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
HMSLTHF_RS13850	ENOG4107R73	Mate efflux family protein
HMSLTHF_RS13855	ENOG4105CRW	Short chain fatty acid transporter
HMSLTHF_RS13860	ENOG4108S4H	thioesterase Superfamily protein
HMSLTHF_RS13880	ENOG4105D7V	transposase
HMSLTHF_RS13885	ENOG4108RS6	transposase
HMSLTHF_RS13915	ENOG4105BZW	Glycerate kinase
HMSLTHF_RS13920	ENOG4108RMU	ferritin dps family protein
HMSLTHF_RS13925	ENOG4105CIN	aminoacyl-histidine dipeptidase
HMSLTHF_RS13930	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
HMSLTHF_RS13935	ENOG4105CH5	extracellular solute-binding protein, family 7
HMSLTHF_RS13945	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HMSLTHF_RS13950	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
HMSLTHF_RS13955	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HMSLTHF_RS13960	ENOG4107QKW	extracellular solute-binding protein family 1
HMSLTHF_RS13965	ENOG4105C2M	dna polymerase I
HMSLTHF_RS13970	ENOG4105CUV	Homoserine Kinase
HMSLTHF_RS13975	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
HMSLTHF_RS13980	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
HMSLTHF_RS13985	ENOG4105EV8	ectoine hydroxylase
HMSLTHF_RS13995	ENOG4105C0D	helicase
HMSLTHF_RS14000	ENOG4105VN1	Heat shock protein
HMSLTHF_RS14035	ENOG4105MEH	
HMSLTHF_RS14100	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
HMSLTHF_RS14105	ENOG4105CEN	a g-specific adenine glycosylase
HMSLTHF_RS14120	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
HMSLTHF_RS14125	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
HMSLTHF_RS14130	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
HMSLTHF_RS14135	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
HMSLTHF_RS14145	ENOG4105R2J	Conserved Protein
HMSLTHF_RS14155	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
HMSLTHF_RS14160	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
HMSLTHF_RS14165	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
HMSLTHF_RS14175	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HMSLTHF_RS14205	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
HMSLTHF_RS14210	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
HMSLTHF_RS14215	ENOG4105EMY	transcriptional regulator
HMSLTHF_RS14220	ENOG4108ZP8	Acetolactate synthase small subunit
HMSLTHF_RS14225	ENOG4105C7K	acetolactate synthase
HMSLTHF_RS14230	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HMSLTHF_RS14235	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
HMSLTHF_RS14240	ENOG4105C34	Pseudouridine synthase
HMSLTHF_RS14245	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HMSLTHF_RS14250	ENOG4105C4K	Nad synthetase
HMSLTHF_RS14260	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
HMSLTHF_RS14270	ENOG4105C3M	thioredoxin reductase
HMSLTHF_RS14275	ENOG4107QM5	aconitate hydratase
HMSLTHF_RS14300	ENOG4108RS6	transposase
HMSLTHF_RS14305	ENOG41066VF	YeeE YedE family protein
HMSLTHF_RS14310	ENOG4105C31	Tryptophanyl-tRNA synthetase
HMSLTHF_RS14335	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
HMSLTHF_RS14340	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
HMSLTHF_RS14350	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
HMSLTHF_RS14355	ENOG4105DTN	riboflavin biosynthesis protein ribF
HMSLTHF_RS14360	ENOG4105CJR	Integral membrane protein (MviN
HMSLTHF_RS14365	ENOG41082GY	Binds directly to 16S ribosomal RNA (By similarity)
HMSLTHF_RS14375	ENOG4105VT3	DNA binding domain protein, excisionase family
HMSLTHF_RS14450	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
HMSLTHF_RS14455	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
HMSLTHF_RS14465	ENOG4108UT6	Transferase hexapeptide repeat containing protein
HMSLTHF_RS14485	ENOG4105I03	Flagellin
HMSLTHF_RS14490	ENOG4105DTS	flagellar hook-associated
HMSLTHF_RS14500	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
HMSLTHF_RS14510	ENOG4108TPP	exopolysaccharide synthesis
HMSLTHF_RS14520	ENOG4105E3A	(ABC) transporter
HMSLTHF_RS14525	ENOG4105DA5	(ABC) transporter
HMSLTHF_RS14535	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
HMSLTHF_RS14550	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HMSLTHF_RS14560	ENOG4105GQU	Trap dicarboxylate transporter, dctp subunit
HMSLTHF_RS14570	ENOG4105EMU	Dehydrogenase
HMSLTHF_RS14580	ENOG4105C5X	domain protein
HMSLTHF_RS14585	ENOG4105ETS	cytosine purines uracil thiamine allantoin
HMSLTHF_RS14590	ENOG4105C7K	acetolactate synthase
HMSLTHF_RS14595	ENOG4105DWD	nucleoside recognition domain protein
HMSLTHF_RS14600	ENOG4105CYW	agmatinase
HMSLTHF_RS14605	ENOG4108JUB	Transcriptional regulator
HMSLTHF_RS14615	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HMSLTHF_RS14635	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
HMSLTHF_RS14640	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
HMSLTHF_RS14645	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
HMSLTHF_RS14650	ENOG4105CT5	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity)
HMSLTHF_RS14655	ENOG4107RUZ	Sss sodium solute transporter superfamily
HMSLTHF_RS14660	ENOG4105Z6B	inner membrane protein yjfl
HMSLTHF_RS14670	ENOG4106032	Glutathionylspermidine synthase
HMSLTHF_RS14675	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
HMSLTHF_RS14680	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
HMSLTHF_RS14695	ENOG4105QAX	Iron-sulfur
HMSLTHF_RS14700	ENOG4108IEG	Formate dehydrogenase Alpha subunit
HMSLTHF_RS14730	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
HMSLTHF_RS14735	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
HMSLTHF_RS14740	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
HMSLTHF_RS14745	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HMSLTHF_RS14750	ENOG4105CKI	cobalamin synthesis protein
HMSLTHF_RS14755	ENOG4105BZU	Histidine kinase
HMSLTHF_RS14760	ENOG4105EVZ	LysR family transcriptional regulator
HMSLTHF_RS14765	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
HMSLTHF_RS14775	ENOG4105CD3	dihydroorotase
HMSLTHF_RS14780	ENOG4105BZ8	glutamate synthase
HMSLTHF_RS14785	ENOG4107SJI	Dehydrogenase
HMSLTHF_RS14805	ENOG4105F35	Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity)
HMSLTHF_RS14810	ENOG4105DE9	3-keto-5-aminohexanoate cleavage enzyme
HMSLTHF_RS14835	ENOG4105BZU	Histidine kinase
HMSLTHF_RS14840	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
HMSLTHF_RS14845	ENOG4105DZC	cytosine deaminase
HMSLTHF_RS14850	ENOG4108UIN	ybak prolyl-trna synthetase associated region
HMSLTHF_RS14855	ENOG4105KD7	acetyltransferase
HMSLTHF_RS14860	ENOG4105VE1	Phosphatidylcholine synthase
HMSLTHF_RS14865	ENOG4108R3E	Dna-3-methyladenine glycosylase i
HMSLTHF_RS14870	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HMSLTHF_RS14885	ENOG4105CC0	LysR family Transcriptional regulator
HMSLTHF_RS14895	ENOG4105E5Q	amino acid AbC transporter
HMSLTHF_RS14900	ENOG4105E5Q	amino acid AbC transporter
HMSLTHF_RS14915	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
HMSLTHF_RS14920	ENOG4105CYW	agmatinase
HMSLTHF_RS14925	ENOG4108R86	Transcriptional regulator
HMSLTHF_RS14930	ENOG4105C26	Dehydrogenase
HMSLTHF_RS14935	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
HMSLTHF_RS14950	ENOG4105DRR	Transcriptional regulator, GntR family
HMSLTHF_RS14955	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
HMSLTHF_RS14960	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HMSLTHF_RS14965	ENOG4105CEY	Amp-dependent synthetase and ligase
HMSLTHF_RS14970	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
HMSLTHF_RS14975	ENOG4108IPT	Naphthoate synthase
HMSLTHF_RS14980	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
HMSLTHF_RS14990	ENOG4105E33	succinate dehydrogenase
HMSLTHF_RS15010	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
HMSLTHF_RS15015	ENOG4105E4F	Isochorismate synthase
HMSLTHF_RS15025	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
HMSLTHF_RS15030	ENOG4106EQQ	Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity)
HMSLTHF_RS15035	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HMSLTHF_RS15040	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
HMSLTHF_RS15070	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HMSLTHF_RS15085	ENOG4105C5H	ABC transporter
HMSLTHF_RS15100	ENOG4105D7V	transposase
HMSLTHF_RS15130	ENOG4105BZS	acriflavin resistance protein
HMSLTHF_RS15140	ENOG4105ZXK	Dehydrogenase
HMSLTHF_RS15150	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HMSLTHF_RS15160	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
HMSLTHF_RS15165	ENOG4105EXW	epimerase dehydratase
HMSLTHF_RS15170	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
HMSLTHF_RS15175	ENOG4105FB2	class II Aldolase
HMSLTHF_RS15185	ENOG4105ZXK	Dehydrogenase
HMSLTHF_RS15190	ENOG4105DIQ	Transcriptional regulator
HMSLTHF_RS15205	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HMSLTHF_RS15215	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
HMSLTHF_RS15220	ENOG4105HDK	L-asparaginase
HMSLTHF_RS15225	ENOG4105JXH	GntR family transcriptional regulator
HMSLTHF_RS15245	ENOG4105CJW	magnesium transporter
HMSLTHF_RS15280	ENOG4108RS6	transposase
HMSLTHF_RS15285	ENOG4105E54	alpha-amylase
HMSLTHF_RS15290	ENOG4105BZU	Histidine kinase
HMSLTHF_RS15295	ENOG4105BZU	Histidine kinase
HMSLTHF_RS15300	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HMSLTHF_RS15315	ENOG4105C5Q	Transcriptional regulator
HMSLTHF_RS15320	ENOG4105E7W	lamb ycsf family protein
HMSLTHF_RS15325	ENOG4105P4J	Allophanate hydrolase, subunit 1
HMSLTHF_RS15330	ENOG4107R7A	Allophanate hydrolase subunit 2
HMSLTHF_RS15335	ENOG4105CK7	Sodium proline symporter
HMSLTHF_RS15345	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
HMSLTHF_RS15350	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HMSLTHF_RS15355	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HMSLTHF_RS15365	ENOG4105CYW	agmatinase
HMSLTHF_RS15425	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
HMSLTHF_RS15450	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HMSLTHF_RS15465	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
HMSLTHF_RS15475	ENOG4105C30	Nad-dependent epimerase dehydratase
HMSLTHF_RS15480	ENOG4105CMR	udp-glucose 4-epimerase
HMSLTHF_RS15490	ENOG4105CMR	udp-glucose 4-epimerase
HMSLTHF_RS15510	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
HMSLTHF_RS15515	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
HMSLTHF_RS15520	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
HMSLTHF_RS15530	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
HMSLTHF_RS15550	ENOG4105D7V	transposase
HMSLTHF_RS15570	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
HMSLTHF_RS15580	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HMSLTHF_RS15585	ENOG4105C8Q	Methyl-accepting chemotaxis
HMSLTHF_RS15590	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
HMSLTHF_RS15595	ENOG4105IY8	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
HMSLTHF_RS15600	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
HMSLTHF_RS15605	ENOG4105CQM	Urea amidohydrolase subunit alpha
HMSLTHF_RS15610	ENOG4105KI2	Urea amidohydrolase subunit beta
HMSLTHF_RS15615	ENOG4108YZ9	Urea amidohydrolase subunit gamma
HMSLTHF_RS15620	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
HMSLTHF_RS15635	ENOG4105BZU	Histidine kinase
HMSLTHF_RS15640	ENOG4108IV0	ABC, transporter
HMSLTHF_RS15645	ENOG4105C0Z	ABC transporter
HMSLTHF_RS15655	ENOG4105C32	Amino acid ABC transporter (Permease)
HMSLTHF_RS15680	ENOG4108V9W	transcriptional regulatory protein
HMSLTHF_RS15685	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
HMSLTHF_RS15700	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
HMSLTHF_RS15705	ENOG4105D7T	ABC transporter
HMSLTHF_RS15710	ENOG4107XKF	NMT1 THI5 Like Domain Protein
HMSLTHF_RS15720	ENOG4105I03	Flagellin
HMSLTHF_RS15725	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HMSLTHF_RS15730	ENOG410642E	Short chain dehydrogenase
HMSLTHF_RS15735	ENOG4105D8X	mechanosensitive ion channel
HMSLTHF_RS15740	ENOG4105W39	Membrane
HMSLTHF_RS15745	ENOG41069M3	Transcriptional regulator
HMSLTHF_RS15750	ENOG4105C72	UPF0176 protein
HMSLTHF_RS15760	ENOG4108JQ1	Dehydrogenase
HMSLTHF_RS15765	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HMSLTHF_RS15770	ENOG4105CTB	Polyprenyl synthetase
HMSLTHF_RS15775	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
HMSLTHF_RS15780	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
HMSLTHF_RS15785	ENOG4108RXX	maleylacetoacetate isomerase
HMSLTHF_RS15810	ENOG4106H31	ATP-dependent protease ATP-binding subunit-like protein
HMSLTHF_RS15815	ENOG4105DCY	Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide (By similarity)
HMSLTHF_RS15820	ENOG4108IV0	ABC, transporter
HMSLTHF_RS15825	ENOG4105C0Z	ABC transporter
HMSLTHF_RS15840	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
HMSLTHF_RS15845	ENOG4105BZU	Histidine kinase
HMSLTHF_RS15855	ENOG4105BZU	Histidine kinase
HMSLTHF_RS15865	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
HMSLTHF_RS15870	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
HMSLTHF_RS15875	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
HMSLTHF_RS15885	ENOG4107QXX	ABC transporter
HMSLTHF_RS15890	ENOG4105EZ7	amino acid ABC transporter
HMSLTHF_RS15895	ENOG4105DRP	amino acid AbC transporter
HMSLTHF_RS15900	ENOG4105CDA	abc transporter atp-binding protein
HMSLTHF_RS15915	ENOG4105C8Q	Methyl-accepting chemotaxis
HMSLTHF_RS15925	ENOG4105DUM	transcriptional regulator, lysR family
HMSLTHF_RS15930	ENOG4105DP0	ferredoxin-NADP reductase
HMSLTHF_RS15935	ENOG4108YZA	Nitrogen regulatory protein pii
HMSLTHF_RS15945	ENOG4108YZA	Nitrogen regulatory protein pii
HMSLTHF_RS15950	ENOG4105W0Z	cytoplasmic protein
HMSLTHF_RS15955	ENOG4105J76	Periplasmic binding protein
HMSLTHF_RS15960	ENOG4105C0P	Mg chelatase subunit ChlI
HMSLTHF_RS15985	ENOG4105ZEG	Suppressor protein
HMSLTHF_RS15990	ENOG4105C0P	Mg chelatase subunit ChlI
HMSLTHF_RS16000	ENOG4107QP3	malate synthase g
HMSLTHF_RS16010	ENOG4105C7W	Xanthine dehydrogenase
HMSLTHF_RS16015	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
HMSLTHF_RS16020	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
HMSLTHF_RS16045	ENOG4105M08	Membrane
HMSLTHF_RS16050	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
HMSLTHF_RS16060	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
HMSLTHF_RS16080	ENOG4108ZX6	Electron transport protein SCO1 SenC
HMSLTHF_RS16090	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HMSLTHF_RS16095	ENOG41080TK	Universal stress protein
HMSLTHF_RS16100	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HMSLTHF_RS16105	ENOG4108K1J	Transporter DctQ
HMSLTHF_RS16110	ENOG4108KJ1	Trap dicarboxylate transporter, dctp subunit
HMSLTHF_RS16120	ENOG4105C5H	ABC transporter
HMSLTHF_RS16125	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
HMSLTHF_RS16135	ENOG4105DWF	phosphomethylpyrimidine kinase
HMSLTHF_RS16140	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HMSLTHF_RS16155	ENOG4108Z33	Thiol disulfide Interchange Protein
HMSLTHF_RS16160	ENOG4106RE7	Cytochrome
HMSLTHF_RS16165	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
HMSLTHF_RS16170	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
HMSLTHF_RS16175	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HMSLTHF_RS16185	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
HMSLTHF_RS16190	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
HMSLTHF_RS16200	ENOG4105CH7	arginosuccinase
HMSLTHF_RS16205	ENOG4105BZU	Histidine kinase
HMSLTHF_RS16220	ENOG4105ECF	c-methyltransferase
HMSLTHF_RS16235	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
HMSLTHF_RS16240	ENOG4105E32	cytoplasmic protein
HMSLTHF_RS16245	ENOG41081XQ	Conserved Protein
HMSLTHF_RS16250	ENOG4105C8J	)-transporter
HMSLTHF_RS16260	ENOG4106KNT	transcriptional regulator
HMSLTHF_RS16265	ENOG4105C4R	Atp-dependent dna helicase
HMSLTHF_RS16270	ENOG4105CH5	extracellular solute-binding protein, family 7
HMSLTHF_RS16275	ENOG4105NAU	thioesterase Superfamily protein
HMSLTHF_RS16285	ENOG4105C8U	phosphate abc transporter
HMSLTHF_RS16290	ENOG4105E2Z	phosphate ABC transporter (Permease
HMSLTHF_RS16295	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
HMSLTHF_RS16300	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
HMSLTHF_RS16320	ENOG4105BZU	Histidine kinase
HMSLTHF_RS16325	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HMSLTHF_RS16330	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
HMSLTHF_RS16335	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
HMSLTHF_RS16340	ENOG4107QZF	nitrite reductase NADPH large subunit
HMSLTHF_RS16345	ENOG4105NYX	DNA-binding protein
HMSLTHF_RS16355	ENOG41090KR	LysR family transcriptional Regulator
HMSLTHF_RS16385	ENOG4105EM2	membrane
HMSLTHF_RS16390	ENOG4105CB5	ATP-dependent DNA helicase recG
HMSLTHF_RS16395	ENOG4105C5Q	Transcriptional regulator
HMSLTHF_RS16405	ENOG4105KME	endoribonuclease L-psp
HMSLTHF_RS16410	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HMSLTHF_RS16415	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
HMSLTHF_RS16420	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
HMSLTHF_RS16435	ENOG4105F27	Major Facilitator
HMSLTHF_RS16460	ENOG4105EUB	pirin domain protein
HMSLTHF_RS16475	ENOG4105J0Q	Transcriptional regulator
HMSLTHF_RS16535	ENOG4105C0D	helicase
HMSLTHF_RS16540	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
HMSLTHF_RS16555	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
HMSLTHF_RS16595	ENOG4105DSJ	YicC domain protein
HMSLTHF_RS16600	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
HMSLTHF_RS16610	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
HMSLTHF_RS16615	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
HMSLTHF_RS16620	ENOG4105C4R	Atp-dependent dna helicase
HMSLTHF_RS16635	ENOG4105DN9	Na H antiporter
HMSLTHF_RS16640	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HMSLTHF_RS16645	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HMSLTHF_RS16650	ENOG4105CJ2	(LipO)protein
HMSLTHF_RS16655	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
HMSLTHF_RS16665	ENOG4105CJW	magnesium transporter
HMSLTHF_RS16670	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
HMSLTHF_RS16675	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
HMSLTHF_RS16680	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
HMSLTHF_RS16685	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
HMSLTHF_RS16690	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HMSLTHF_RS16695	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HMSLTHF_RS16705	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
HMSLTHF_RS16715	ENOG4105FA0	parb-like partition protein
HMSLTHF_RS16720	ENOG4107QJE	Chromosome Partitioning Protein
HMSLTHF_RS16725	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
HMSLTHF_RS16730	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
HMSLTHF_RS16735	ENOG4105CDA	abc transporter atp-binding protein
HMSLTHF_RS16740	ENOG4105E5Q	amino acid AbC transporter
HMSLTHF_RS16745	ENOG4107R0W	ABC transporter
HMSLTHF_RS16750	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
HMSLTHF_RS16755	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
HMSLTHF_RS16765	ENOG4108YXA	Membrane
HMSLTHF_RS16770	ENOG4105DWF	phosphomethylpyrimidine kinase
HMSLTHF_RS16775	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
HMSLTHF_RS16795	ENOG4105P8Q	Curli production assembly transport component CsgG
HMSLTHF_RS16810	ENOG41086KC	Transcriptional regulator
HMSLTHF_RS16815	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
HMSLTHF_RS16820	ENOG4105CSA	Coproporphyrinogen iii oxidase
HMSLTHF_RS16825	ENOG4108ZG0	Ompa motb domain protein
HMSLTHF_RS16830	ENOG4105D6S	protein involved in catabolism of external DNA
HMSLTHF_RS16835	ENOG41080ET	plasmid maintenance system killer protein
HMSLTHF_RS16840	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
HMSLTHF_RS16850	ENOG4105DS1	cytochrome b561
HMSLTHF_RS16855	ENOG4105CPC	Aldo Keto reductase
HMSLTHF_RS16860	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
HMSLTHF_RS16865	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
HMSLTHF_RS16870	ENOG410642W	LysR family Transcriptional regulator
HMSLTHF_RS16890	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
HMSLTHF_RS16895	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HMSLTHF_RS16900	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
HMSLTHF_RS16905	ENOG4105VG0	50S ribosomal protein l34