locus-tag	class	description
G3568_RS00010	COG2267	carboxylic ester hydrolase activity
G3568_RS00015	COG0300	oxidoreductase activity
G3568_RS00030	COG2814	Major facilitator Superfamily
G3568_RS00035	COG0583	DNA-binding transcription factor activity
G3568_RS00055	COG3706	GGDEF domain
G3568_RS00080	COG3177	Filamentation induced by cAMP protein fic
G3568_RS00095	COG4948	Mandelate Racemase Muconate Lactonizing
G3568_RS00115	COG2186	Transcriptional regulator
G3568_RS00125	COG0129	dihydroxy-acid dehydratase activity
G3568_RS00130	COG1472	Belongs to the glycosyl hydrolase 3 family
G3568_RS00135	COG0477	Major facilitator Superfamily
G3568_RS00160	COG0395	ABC-type sugar transport system, permease component
G3568_RS00165	COG1175	transmembrane transport
G3568_RS00170	COG1653	transport
G3568_RS00175	COG1028	Short-chain dehydrogenase reductase Sdr
G3568_RS00195	COG0673	inositol 2-dehydrogenase activity
G3568_RS00205	COG1879	ABC-type sugar transport system periplasmic component
G3568_RS00210	COG1172	Belongs to the binding-protein-dependent transport system permease family
G3568_RS00220	COG1028	Short-chain dehydrogenase reductase Sdr
G3568_RS00280	COG0129	dihydroxy-acid dehydratase activity
G3568_RS00290	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G3568_RS00300	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G3568_RS00320	COG1609	Transcriptional regulator
G3568_RS00330	COG4149	molybdate abc transporter
G3568_RS00335	COG1177	transmembrane transport
G3568_RS00340	COG3842	ATPase activity
G3568_RS00345	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
G3568_RS00355	COG1609	Transcriptional regulator
G3568_RS00365	COG0673	inositol 2-dehydrogenase activity
G3568_RS00370	COG1129	ABC transporter
G3568_RS00375	COG1172	Belongs to the binding-protein-dependent transport system permease family
G3568_RS00380	COG1879	ABC-type sugar transport system periplasmic component
G3568_RS00385	COG0435	Glutathione S-transferase
G3568_RS00395	COG1741	Belongs to the pirin family
G3568_RS00400	COG0739	heme binding
G3568_RS00405	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
G3568_RS00410	COG1953	Uracil, thiamine, allantoin
G3568_RS00440	COG1309	transcriptional regulator
G3568_RS00445	COG2223	nitrite transmembrane transporter activity
G3568_RS00450	COG3707	response regulator
G3568_RS00455	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G3568_RS00460	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3568_RS00465	COG1116	anion transmembrane transporter activity
G3568_RS00495	COG2186	Transcriptional regulator
G3568_RS00500	COG0179	Fumarylacetoacetate (FAA) hydrolase
G3568_RS00515	COG0678	peroxiredoxin activity
G3568_RS00525	COG2815	serine threonine protein kinase
G3568_RS00525	COG0515	serine threonine protein kinase
G3568_RS00535	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G3568_RS00535	COG1648	precorrin-2 dehydrogenase activity
G3568_RS00540	COG0243	molybdopterin cofactor binding
G3568_RS00545	COG3707	response regulator
G3568_RS00550	COG1116	anion transmembrane transporter activity
G3568_RS00550	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G3568_RS00555	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G3568_RS00560	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G3568_RS00560	COG2146	nitrite reductase [NAD(P)H] activity
G3568_RS00625	COG3788	relative of glutathione S-transferase, MAPEG superfamily
G3568_RS00640	COG2814	Major facilitator Superfamily
G3568_RS00665	COG0028	Belongs to the TPP enzyme family
G3568_RS00675	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
G3568_RS00690	COG2010	Cytochrome c
G3568_RS00700	COG0651	ATP synthesis coupled electron transport
G3568_RS00705	COG0651	ATP synthesis coupled electron transport
G3568_RS00710	COG0651	ATP synthesis coupled electron transport
G3568_RS00725	COG0400	carboxylic ester hydrolase activity
G3568_RS00730	COG1278	Cold shock
G3568_RS00735	COG2989	Protein conserved in bacteria
G3568_RS00755	COG0412	Dienelactone hydrolase
G3568_RS00765	COG1396	sequence-specific DNA binding
G3568_RS00780	COG1487	ribonuclease activity
G3568_RS00795	COG0385	Bile acid
G3568_RS00800	COG0471	metal ion transport
G3568_RS00805	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G3568_RS00815	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G3568_RS00825	COG1250	3-hydroxyacyl-CoA dehydrogenase
G3568_RS00830	COG3246	L-lysine catabolic process to acetate
G3568_RS00835	COG1609	Transcriptional regulator
G3568_RS00850	COG1028	Short-chain dehydrogenase reductase Sdr
G3568_RS00865	COG1116	anion transmembrane transporter activity
G3568_RS00870	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3568_RS00945	COG3181	Tripartite tricarboxylate transporter family receptor
G3568_RS00950	COG4948	Mandelate Racemase Muconate Lactonizing
G3568_RS00955	COG1802	Transcriptional regulator
G3568_RS00970	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G3568_RS00980	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G3568_RS01015	COG0582	viral genome integration into host DNA
G3568_RS01030	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G3568_RS01035	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G3568_RS01040	COG1780	Probably involved in ribonucleotide reductase function
G3568_RS01045	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
G3568_RS01050	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
G3568_RS01065	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G3568_RS01070	COG4615	Cyclic peptide transporter
G3568_RS01090	COG1120	ATPase activity
G3568_RS01130	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G3568_RS01140	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
G3568_RS01140	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G3568_RS01155	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G3568_RS01170	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
G3568_RS01240	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
G3568_RS01255	COG2133	pyrroloquinoline quinone binding
G3568_RS01280	COG2855	membrane
G3568_RS01290	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
G3568_RS01310	COG2188	Transcriptional regulator
G3568_RS01320	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3568_RS01335	COG0446	pyridine nucleotide-disulphide oxidoreductase
G3568_RS01335	COG1902	pentaerythritol trinitrate reductase activity
G3568_RS01350	COG4191	Histidine kinase
G3568_RS01375	COG3383	formate dehydrogenase (NAD+) activity
G3568_RS01385	COG3237	CsbD-like
G3568_RS01395	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
G3568_RS01425	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
G3568_RS01440	COG0247	lactate metabolic process
G3568_RS01440	COG2181	nitrate reductase activity
G3568_RS01445	COG0446	pyridine nucleotide-disulphide oxidoreductase
G3568_RS01445	COG1902	pentaerythritol trinitrate reductase activity
G3568_RS01460	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G3568_RS01475	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
G3568_RS01480	COG0583	DNA-binding transcription factor activity
G3568_RS01490	COG1760	l-serine dehydratase
G3568_RS01495	COG0583	DNA-binding transcription factor activity
G3568_RS01510	COG0358	DNA primase activity
G3568_RS01515	COG0828	Belongs to the bacterial ribosomal protein bS21 family
G3568_RS01520	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
G3568_RS01525	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
G3568_RS01535	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
G3568_RS01535	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
G3568_RS01540	COG0617	tRNA 3'-terminal CCA addition
G3568_RS01545	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G3568_RS01550	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
G3568_RS01555	COG2967	ApaG domain
G3568_RS01560	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
G3568_RS01565	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
G3568_RS01570	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G3568_RS01585	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
G3568_RS01595	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
G3568_RS01600	COG0537	adenosine 5'-monophosphoramidase activity
G3568_RS01605	COG3954	Phosphoribulokinase
G3568_RS01610	COG0151	Belongs to the GarS family
G3568_RS01635	COG2186	Transcriptional regulator
G3568_RS01650	COG1012	belongs to the aldehyde dehydrogenase family
G3568_RS01660	COG1309	transcriptional regulator
G3568_RS01665	COG0604	alcohol dehydrogenase
G3568_RS01685	COG1024	Enoyl-CoA hydratase
G3568_RS01695	COG1024	Enoyl-CoA hydratase
G3568_RS01700	COG0583	DNA-binding transcription factor activity
G3568_RS01710	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G3568_RS01715	COG4948	Mandelate Racemase Muconate Lactonizing
G3568_RS01720	COG4948	Mandelate Racemase Muconate Lactonizing
G3568_RS01750	COG2951	lytic endotransglycosylase activity
G3568_RS01760	COG1320	monovalent cation:proton antiporter activity
G3568_RS01765	COG2212	antiporter activity
G3568_RS01795	COG2111	Na H antiporter
G3568_RS01795	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
G3568_RS01800	COG1006	Multisubunit Na H antiporter MnhC subunit
G3568_RS01805	COG0651	ATP synthesis coupled electron transport
G3568_RS01810	COG1863	multisubunit Na H antiporter MnhE subunit
G3568_RS01815	COG2212	antiporter activity
G3568_RS01820	COG1320	monovalent cation:proton antiporter activity
G3568_RS01845	COG0305	Participates in initiation and elongation during chromosome replication
G3568_RS01855	COG0800	Aldolase
G3568_RS01860	COG3734	2-keto-3-deoxy-galactonokinase
G3568_RS01865	COG4948	Mandelate Racemase Muconate Lactonizing
G3568_RS01875	COG0359	binds to the 23S rRNA
G3568_RS01885	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
G3568_RS01890	COG0360	Binds together with S18 to 16S ribosomal RNA
G3568_RS01895	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G3568_RS01900	COG0557	exoribonuclease II activity
G3568_RS01940	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G3568_RS01970	COG2719	SpoVR family
G3568_RS01975	COG2718	Belongs to the UPF0229 family
G3568_RS01980	COG2766	serine protein kinase
G3568_RS01985	COG1902	pentaerythritol trinitrate reductase activity
G3568_RS01985	COG0446	pyridine nucleotide-disulphide oxidoreductase
G3568_RS02025	COG3278	Belongs to the heme-copper respiratory oxidase family
G3568_RS02040	COG2010	Cytochrome c
G3568_RS02045	COG0348	domain, Protein
G3568_RS02055	COG2217	Heavy metal translocating P-type atpase
G3568_RS02075	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G3568_RS02080	COG0037	tRNA processing
G3568_RS02100	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G3568_RS02110	COG2205	protein histidine kinase activity
G3568_RS02110	COG2198	Histidine kinase
G3568_RS02110	COG0784	Response regulator, receiver
G3568_RS02120	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G3568_RS02125	COG3091	SprT-like family
G3568_RS02140	COG2937	Belongs to the GPAT DAPAT family
G3568_RS02145	COG0742	ribosomal rna small subunit methyltransferase
G3568_RS02155	COG0563	adenylate kinase activity
G3568_RS02180	COG1720	tRNA m6t6A37 methyltransferase activity
G3568_RS02195	COG3135	benzoate transporter
G3568_RS02200	COG1250	3-hydroxyacyl-CoA dehydrogenase
G3568_RS02200	COG1024	Enoyl-CoA hydratase
G3568_RS02225	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
G3568_RS02245	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G3568_RS02255	COG0425	Belongs to the sulfur carrier protein TusA family
G3568_RS02260	COG4783	chaperone-mediated protein folding
G3568_RS02265	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
G3568_RS02335	COG0582	viral genome integration into host DNA
G3568_RS02355	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
G3568_RS02360	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
G3568_RS02365	COG1061	Type III restriction enzyme res subunit
G3568_RS02375	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
G3568_RS02380	COG2199	diguanylate cyclase activity
G3568_RS02390	COG1946	Acyl-CoA thioesterase
G3568_RS02405	COG0217	transcriptional regulatory protein
G3568_RS02410	COG0006	proline dipeptidase activity
G3568_RS02430	COG1402	creatininase
G3568_RS02435	COG0840	transmembrane signaling receptor activity
G3568_RS02445	COG0513	Belongs to the DEAD box helicase family
G3568_RS02460	COG5001	Diguanylate cyclase
G3568_RS02460	COG4251	negative regulation of phosphorylation
G3568_RS02460	COG3706	GGDEF domain
G3568_RS02460	COG2203	Gaf domain
G3568_RS02465	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
G3568_RS02470	COG0625	glutathione transferase activity
G3568_RS02475	COG3284	Transcriptional regulator
G3568_RS02485	COG1278	Cold shock
G3568_RS02505	COG1028	Short-chain dehydrogenase reductase Sdr
G3568_RS02520	COG0667	Aldo Keto reductase
G3568_RS02525	COG0667	Aldo Keto reductase
G3568_RS02530	COG3443	Belongs to the bacterial solute-binding protein 9 family
G3568_RS02535	COG4773	Receptor
G3568_RS02540	COG1278	Cold shock
G3568_RS02600	COG1280	lysine exporter protein (LysE YggA)
G3568_RS02610	COG0642	Histidine kinase
G3568_RS02615	COG0745	RESPONSE REGULATOR receiver
G3568_RS02625	COG1028	Short-chain dehydrogenase reductase Sdr
G3568_RS02640	COG1028	Short-chain dehydrogenase reductase Sdr
G3568_RS02650	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
G3568_RS02665	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
G3568_RS02670	COG2207	Transcriptional regulator
G3568_RS02690	COG0583	DNA-binding transcription factor activity
G3568_RS02695	COG0625	glutathione transferase activity
G3568_RS02710	COG0656	L-ascorbic acid biosynthetic process
G3568_RS02730	COG1280	lysine exporter protein (LysE YggA)
G3568_RS02760	COG1396	sequence-specific DNA binding
G3568_RS02795	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G3568_RS02815	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
G3568_RS02830	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
G3568_RS02845	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G3568_RS02845	COG0519	Catalyzes the synthesis of GMP from XMP
G3568_RS02855	COG1570	exodeoxyribonuclease VII activity
G3568_RS02860	COG2204	response regulator
G3568_RS02870	COG2205	protein histidine kinase activity
G3568_RS02875	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
G3568_RS02875	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
G3568_RS02880	COG0306	phosphate transporter
G3568_RS02885	COG1392	Phosphate transport regulator
G3568_RS02890	COG3025	triphosphatase activity
G3568_RS02895	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G3568_RS02900	COG0009	L-threonylcarbamoyladenylate synthase
G3568_RS02905	COG0613	PHP domain protein
G3568_RS02910	COG2350	Protein conserved in bacteria
G3568_RS02915	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
G3568_RS02915	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G3568_RS02925	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
G3568_RS02930	COG3115	cell septum assembly
G3568_RS02935	COG1196	nuclear chromosome segregation
G3568_RS02945	COG3088	subunit of a heme lyase
G3568_RS02960	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
G3568_RS02965	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G3568_RS02980	COG4133	protoheme IX ABC transporter activity
G3568_RS02985	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
G3568_RS02990	COG1739	Uncharacterized protein family UPF0029
G3568_RS03040	COG2059	Chromate
G3568_RS03045	COG2059	Chromate
G3568_RS03060	COG3181	Tripartite tricarboxylate transporter family receptor
G3568_RS03065	COG0179	Fumarylacetoacetate (FAA) hydrolase
G3568_RS03070	COG2059	Chromate
G3568_RS03075	COG2059	Chromate
G3568_RS03100	COG3181	Tripartite tricarboxylate transporter family receptor
G3568_RS03115	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
G3568_RS03120	COG0511	ligase activity, forming carbon-carbon bonds
G3568_RS03120	COG5016	pyruvate
G3568_RS03150	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
G3568_RS03155	COG0527	aspartate kinase activity
G3568_RS03160	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
G3568_RS03165	COG2137	regulation of response to DNA damage stimulus
G3568_RS03170	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
G3568_RS03175	COG1546	Belongs to the CinA family
G3568_RS03180	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
G3568_RS03185	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
G3568_RS03190	COG0148	phosphopyruvate hydratase activity
G3568_RS03195	COG2877	3-deoxy-8-phosphooctulonate synthase activity
G3568_RS03200	COG0504	CTP synthase activity
G3568_RS03205	COG0493	'glutamate synthase
G3568_RS03215	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
G3568_RS03220	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
G3568_RS03255	COG3137	Salt-induced outer membrane protein
G3568_RS03260	COG0281	malic enzyme
G3568_RS03265	COG0254	rRNA binding
G3568_RS03270	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
G3568_RS03275	COG0018	arginyl-trna synthetase
G3568_RS03285	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
G3568_RS03290	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
G3568_RS03310	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
G3568_RS03315	COG0140	phosphoribosyl-ATP diphosphatase activity
G3568_RS03320	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G3568_RS03325	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G3568_RS03335	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
G3568_RS03355	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G3568_RS03370	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
G3568_RS03380	COG0248	Ppx GppA phosphatase
G3568_RS03385	COG0037	tRNA processing
G3568_RS03390	COG0825	malonyl-CoA metabolic process
G3568_RS03395	COG0587	DNA-directed DNA polymerase activity
G3568_RS03400	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
G3568_RS03405	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G3568_RS03410	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G3568_RS03415	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
G3568_RS03420	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G3568_RS03440	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
G3568_RS03455	COG0233	cytoplasmic translational termination
G3568_RS03460	COG0528	UMP kinase activity
G3568_RS03465	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
G3568_RS03470	COG0052	Belongs to the universal ribosomal protein uS2 family
G3568_RS03480	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
G3568_RS03485	COG0436	Aminotransferase
G3568_RS03490	COG1393	Belongs to the ArsC family
G3568_RS03500	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G3568_RS03520	COG0492	ferredoxin-NADP+ reductase activity
G3568_RS03525	COG0450	alkyl hydroperoxide reductase
G3568_RS03545	COG2391	methyltransferase activity
G3568_RS03555	COG0686	Belongs to the AlaDH PNT family
G3568_RS03575	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
G3568_RS03580	COG0267	Belongs to the bacterial ribosomal protein bL33 family
G3568_RS03585	COG0227	Belongs to the bacterial ribosomal protein bL28 family
G3568_RS03590	COG2003	Belongs to the UPF0758 family
G3568_RS03595	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
G3568_RS03600	COG0756	dUTP diphosphatase activity
G3568_RS03610	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
G3568_RS03615	COG1309	transcriptional regulator
G3568_RS03630	COG2177	Part of the ABC transporter FtsEX involved in
G3568_RS03635	COG2884	Cell division ATP-binding protein ftsE
G3568_RS03645	COG0742	ribosomal rna small subunit methyltransferase
G3568_RS03665	COG0271	Belongs to the BolA IbaG family
G3568_RS03670	COG2814	Major facilitator Superfamily
G3568_RS03680	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
G3568_RS03695	COG0789	Transcriptional regulator
G3568_RS03700	COG2217	Heavy metal translocating P-type atpase
G3568_RS03710	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
G3568_RS03725	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G3568_RS03735	COG0335	large ribosomal subunit rRNA binding
G3568_RS03740	COG0336	Belongs to the RNA methyltransferase TrmD family
G3568_RS03745	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
G3568_RS03750	COG0228	four-way junction DNA binding
G3568_RS03755	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
G3568_RS03765	COG4536	flavin adenine dinucleotide binding
G3568_RS03770	COG2814	Major facilitator Superfamily
G3568_RS03785	COG1025	Belongs to the peptidase M16 family
G3568_RS03790	COG2925	Exonuclease
G3568_RS03795	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
G3568_RS03800	COG2894	cell division
G3568_RS03805	COG0850	regulation of cytokinetic process
G3568_RS03815	COG1028	Short-chain dehydrogenase reductase Sdr
G3568_RS03825	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
G3568_RS03845	COG0521	Mo-molybdopterin cofactor biosynthetic process
G3568_RS03860	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
G3568_RS03865	COG1140	nitrate reductase beta subunit
G3568_RS03885	COG2197	response regulator
G3568_RS03945	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
G3568_RS03960	COG0826	peptidase U32
G3568_RS03975	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
G3568_RS03990	COG3154	lipid carrier protein
G3568_RS04000	COG2832	Protein of unknown function (DUF454)
G3568_RS04040	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
G3568_RS04085	COG0667	Aldo Keto reductase
G3568_RS04090	COG3022	response to hydroperoxide
G3568_RS04110	COG2433	Pfam Transposase IS66
G3568_RS04150	COG1183	phosphatidylcholine synthase activity
G3568_RS04155	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
G3568_RS04165	COG0440	acetolactate synthase activity
G3568_RS04170	COG0028	Belongs to the TPP enzyme family
G3568_RS04195	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
G3568_RS04195	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G3568_RS04205	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G3568_RS04260	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
G3568_RS04265	COG1047	Peptidyl-prolyl cis-trans
G3568_RS04270	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
G3568_RS04275	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
G3568_RS04280	COG0196	riboflavin kinase activity
G3568_RS04290	COG0268	Binds directly to 16S ribosomal RNA
G3568_RS04295	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
G3568_RS04300	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
G3568_RS04305	COG0211	Belongs to the bacterial ribosomal protein bL27 family
G3568_RS04310	COG0261	This protein binds to 23S rRNA in the presence of protein L20
G3568_RS04315	COG0142	geranyltranstransferase activity
G3568_RS04335	COG2205	protein histidine kinase activity
G3568_RS04360	COG2223	nitrite transmembrane transporter activity
G3568_RS04365	COG3246	L-lysine catabolic process to acetate
G3568_RS04395	COG2175	clavaminate synthase activity
G3568_RS04430	COG4215	(ABC) transporter
G3568_RS04445	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G3568_RS04455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G3568_RS04460	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
G3568_RS04465	COG1090	epimerase
G3568_RS04470	COG0789	Transcriptional regulator
G3568_RS04475	COG0415	Belongs to the DNA photolyase family
G3568_RS04490	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
G3568_RS04510	COG0629	single-stranded DNA binding
G3568_RS04515	COG2814	Major facilitator Superfamily
G3568_RS04525	COG0203	ribosomal protein L17
G3568_RS04530	COG0202	RNA polymerase activity
G3568_RS04535	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
G3568_RS04540	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
G3568_RS04545	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
G3568_RS04550	COG0257	Belongs to the bacterial ribosomal protein bL36 family
G3568_RS04560	COG0200	Binds to the 23S rRNA
G3568_RS04565	COG1841	ribosomal large subunit assembly
G3568_RS04570	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
G3568_RS04575	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
G3568_RS04580	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
G3568_RS04585	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
G3568_RS04590	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
G3568_RS04595	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
G3568_RS04600	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
G3568_RS04605	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
G3568_RS04610	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
G3568_RS04615	COG0255	Belongs to the universal ribosomal protein uL29 family
G3568_RS04620	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
G3568_RS04625	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
G3568_RS04630	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
G3568_RS04635	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
G3568_RS04640	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
G3568_RS04645	COG0089	rRNA binding
G3568_RS04650	COG0088	Forms part of the polypeptide exit tunnel
G3568_RS04655	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
G3568_RS04660	COG0051	transcription antitermination factor activity, RNA binding
G3568_RS04665	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G3568_RS04670	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
G3568_RS04675	COG0049	tRNA binding
G3568_RS04680	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
G3568_RS04685	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
G3568_RS04690	COG0085	RNA polymerase activity
G3568_RS04695	COG0222	ribosome binding
G3568_RS04700	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
G3568_RS04705	COG0081	regulation of translation
G3568_RS04710	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
G3568_RS04745	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
G3568_RS04790	COG1139	Iron-sulfur cluster binding protein
G3568_RS04795	COG0247	lactate metabolic process
G3568_RS04800	COG2186	Transcriptional regulator
G3568_RS04810	COG2204	response regulator
G3568_RS04825	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
G3568_RS04830	COG0733	neurotransmitter:sodium symporter activity
G3568_RS04835	COG0339	signal peptide processing
G3568_RS04880	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
G3568_RS04885	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
G3568_RS04890	COG1830	Aldolase
G3568_RS04900	COG1346	cytolysis
G3568_RS04910	COG0126	phosphoglycerate kinase activity
G3568_RS04940	COG0546	phosphoglycolate phosphatase activity
G3568_RS04945	COG0023	Translation Initiation Factor
G3568_RS04975	COG2204	response regulator
G3568_RS04980	COG3852	Histidine kinase
G3568_RS05045	COG1063	alcohol dehydrogenase
G3568_RS05050	COG0156	8-amino-7-oxononanoate synthase activity
G3568_RS05060	COG0733	neurotransmitter:sodium symporter activity
G3568_RS05100	COG0583	DNA-binding transcription factor activity
G3568_RS05120	COG0583	DNA-binding transcription factor activity
G3568_RS05125	COG2855	membrane
G3568_RS05155	COG2161	toxin-antitoxin pair type II binding
G3568_RS05160	COG4115	mRNA cleavage
G3568_RS05165	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
G3568_RS05170	COG1518	maintenance of DNA repeat elements
G3568_RS05185	COG1857	crispr-associated protein
G3568_RS05200	COG1203	CRISPR-associated helicase, Cas3
G3568_RS05205	COG0584	glycerophosphoryl diester phosphodiesterase
G3568_RS05215	COG1283	sodium-dependent phosphate transmembrane transporter activity
G3568_RS05220	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G3568_RS05230	COG1121	(ABC) transporter
G3568_RS05235	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G3568_RS05240	COG0803	Belongs to the bacterial solute-binding protein 9 family
G3568_RS05255	COG4181	ATPase activity
G3568_RS05295	COG0791	NLP P60 protein
G3568_RS05300	COG1321	iron dependent repressor
G3568_RS05310	COG1121	(ABC) transporter
G3568_RS05315	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G3568_RS05325	COG1840	ABC-type Fe3 transport system, periplasmic component
G3568_RS05330	COG4149	molybdate abc transporter
G3568_RS05335	COG0697	spore germination
G3568_RS05390	COG0583	DNA-binding transcription factor activity
G3568_RS05395	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
G3568_RS05400	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
G3568_RS05405	COG1984	allophanate hydrolase subunit 2
G3568_RS05410	COG0411	ABC transporter
G3568_RS05450	COG5441	Belongs to the UPF0261 family
G3568_RS05455	COG5564	TIM-barrel signal transduction protein
G3568_RS05460	COG0559	Belongs to the binding-protein-dependent transport system permease family
G3568_RS05485	COG3530	Putative quorum-sensing-regulated virulence factor
G3568_RS05490	COG0730	response to heat
G3568_RS05500	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
G3568_RS05510	COG3181	Tripartite tricarboxylate transporter family receptor
G3568_RS05515	COG0028	Belongs to the TPP enzyme family
G3568_RS05530	COG0210	DNA helicase
G3568_RS05535	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
G3568_RS05545	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
G3568_RS05550	COG0708	Exodeoxyribonuclease III
G3568_RS05555	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
G3568_RS05570	COG1172	Belongs to the binding-protein-dependent transport system permease family
G3568_RS05575	COG1172	Belongs to the binding-protein-dependent transport system permease family
G3568_RS05595	COG1561	YicC-like family, N-terminal region
G3568_RS05640	COG2003	Belongs to the UPF0758 family
G3568_RS05645	COG1477	protein flavinylation
G3568_RS05650	COG0569	domain protein
G3568_RS05660	COG2205	protein histidine kinase activity
G3568_RS05665	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
G3568_RS05670	COG1376	ErfK ybiS ycfS ynhG family protein
G3568_RS05670	COG1388	LysM domain
G3568_RS05675	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
G3568_RS05685	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G3568_RS05705	COG2132	Multicopper oxidase
G3568_RS05715	COG2217	Heavy metal translocating P-type atpase
G3568_RS05780	COG0725	ABC transporter, periplasmic molybdate-binding protein
G3568_RS05790	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
G3568_RS05795	COG4208	sulfate ABC transporter
G3568_RS05805	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
G3568_RS05810	COG0583	DNA-binding transcription factor activity
G3568_RS05825	COG2814	Major facilitator Superfamily
G3568_RS05830	COG3454	Phosphonate metabolism
G3568_RS05835	COG3639	organic phosphonate transmembrane transporter activity
G3568_RS05840	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
G3568_RS05850	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
G3568_RS05855	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
G3568_RS05860	COG3454	Phosphonate metabolism
G3568_RS05865	COG4778	phosphonate C-P lyase system protein PhnL
G3568_RS05870	COG4107	phosphonate C-P lyase system protein PhnK
G3568_RS05875	COG3627	carbon phosphorus lyase activity
G3568_RS05880	COG3626	phosphonate metabolism
G3568_RS05890	COG3624	Phosphonate C-P lyase system protein PhnG
G3568_RS05895	COG2188	Transcriptional regulator
G3568_RS05900	COG3639	organic phosphonate transmembrane transporter activity
G3568_RS05905	COG3639	organic phosphonate transmembrane transporter activity
G3568_RS05915	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
G3568_RS05920	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G3568_RS05925	COG0194	GDP metabolic process
G3568_RS05930	COG1758	RNA polymerase activity
G3568_RS05935	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G3568_RS05960	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
G3568_RS05965	COG1289	transmembrane transporter activity
G3568_RS05985	COG3161	chorismate lyase activity
G3568_RS05990	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
G3568_RS06005	COG4166	transmembrane transport
G3568_RS06015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G3568_RS06020	COG0444	Belongs to the ABC transporter superfamily
G3568_RS06025	COG4608	Belongs to the ABC transporter superfamily
G3568_RS06040	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G3568_RS06045	COG0573	inorganic phosphate transmembrane transporter activity
G3568_RS06050	COG0573	inorganic phosphate transmembrane transporter activity
G3568_RS06060	COG1607	acyl-coa hydrolase
G3568_RS06065	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
G3568_RS06070	COG0210	DNA helicase
G3568_RS06075	COG1737	Transcriptional regulator
G3568_RS06085	COG1801	Protein of unknown function DUF72
G3568_RS06095	COG1349	DNA-binding transcription factor activity
G3568_RS06100	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
G3568_RS06105	COG1477	protein flavinylation
G3568_RS06110	COG1968	undecaprenyl-diphosphatase activity
G3568_RS06115	COG2239	Acts as a magnesium transporter
G3568_RS06120	COG0355	proton-transporting ATP synthase activity, rotational mechanism
G3568_RS06130	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
G3568_RS06135	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
G3568_RS06140	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
G3568_RS06145	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
G3568_RS06155	COG0356	it plays a direct role in the translocation of protons across the membrane
G3568_RS06165	COG1475	DNA binding
G3568_RS06170	COG1192	Involved in chromosome partitioning
G3568_RS06175	COG0357	Ribosomal RNA small subunit methyltransferase G
G3568_RS06180	COG0445	tRNA wobble uridine modification
G3568_RS06185	COG1126	abc transporter atp-binding protein
G3568_RS06190	COG0765	amino acid transport
G3568_RS06195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G3568_RS06200	COG0316	Belongs to the HesB IscA family
G3568_RS06205	COG0038	chloride channel
G3568_RS06215	COG0351	phosphomethylpyrimidine kinase
G3568_RS06225	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
G3568_RS06265	COG2204	response regulator
G3568_RS06275	COG2197	response regulator
G3568_RS06285	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G3568_RS06290	COG2885	chlorophyll binding
G3568_RS06295	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
G3568_RS06305	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
G3568_RS06310	COG0706	membrane insertase activity
G3568_RS06315	COG0594	ribonuclease P activity
G3568_RS06320	COG0230	Belongs to the bacterial ribosomal protein bL34 family
G3568_RS06325	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
G3568_RS06330	COG0592	DNA-directed DNA polymerase activity
G3568_RS06335	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
G3568_RS06350	COG0751	glycine-tRNA ligase activity
G3568_RS06355	COG0752	glycyl-tRNA synthetase alpha subunit
G3568_RS06360	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G3568_RS06375	COG0463	Glycosyl transferase, family 2
G3568_RS06380	COG0859	PFAM glycosyl transferase family 9
G3568_RS06400	COG0859	PFAM glycosyl transferase family 9
G3568_RS06405	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
G3568_RS06405	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
G3568_RS06410	COG1519	Transferase
G3568_RS06415	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
G3568_RS06425	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
G3568_RS06445	COG0006	proline dipeptidase activity
G3568_RS06450	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G3568_RS06460	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G3568_RS06475	COG1176	ABC-type spermidine putrescine transport system, permease component I
G3568_RS06485	COG3842	ATPase activity
G3568_RS06495	COG0793	Belongs to the peptidase S41A family
G3568_RS06500	COG4942	peptidase
G3568_RS06505	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
G3568_RS06510	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G3568_RS06515	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
G3568_RS06520	COG1385	rRNA (uridine-N3-)-methyltransferase activity
G3568_RS06530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G3568_RS06550	COG0745	RESPONSE REGULATOR receiver
G3568_RS06555	COG2205	protein histidine kinase activity
G3568_RS06560	COG2186	Transcriptional regulator
G3568_RS06565	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G3568_RS06585	COG4948	Mandelate Racemase Muconate Lactonizing
G3568_RS06600	COG0189	ligase activity
G3568_RS06605	COG1678	Uncharacterized ACR, COG1678
G3568_RS06610	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
G3568_RS06620	COG0540	Belongs to the ATCase OTCase family
G3568_RS06625	COG1028	Short-chain dehydrogenase reductase Sdr
G3568_RS06635	COG3648	Uricase
G3568_RS06635	COG3195	allantoin biosynthetic process
G3568_RS06640	COG2351	hydroxyisourate hydrolase activity
G3568_RS06665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G3568_RS06675	COG0444	Belongs to the ABC transporter superfamily
G3568_RS06685	COG1953	Uracil, thiamine, allantoin
G3568_RS06705	COG1288	antiporter activity
G3568_RS06710	COG3257	ureidoglycine aminohydrolase activity
G3568_RS06715	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
G3568_RS06720	COG3960	tartronate-semialdehyde synthase activity
G3568_RS06725	COG3622	Belongs to the hyi family
G3568_RS06730	COG2084	Dehydrogenase
G3568_RS06745	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3568_RS06785	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G3568_RS06795	COG4948	Mandelate Racemase Muconate Lactonizing
G3568_RS06815	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G3568_RS06820	COG1722	exodeoxyribonuclease VII activity
G3568_RS06825	COG0142	geranyltranstransferase activity
G3568_RS06830	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
G3568_RS06885	COG2204	response regulator
G3568_RS06940	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
G3568_RS06945	COG0625	glutathione transferase activity
G3568_RS06950	COG1272	protein, Hemolysin III
G3568_RS06955	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G3568_RS06960	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
G3568_RS06970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G3568_RS06975	COG4597	amino acid ABC transporter
G3568_RS06980	COG0765	amino acid transport
G3568_RS06985	COG1126	abc transporter atp-binding protein
G3568_RS06990	COG3706	GGDEF domain
G3568_RS07010	COG3639	organic phosphonate transmembrane transporter activity
G3568_RS07035	COG0583	DNA-binding transcription factor activity
G3568_RS07045	COG0347	Belongs to the P(II) protein family
G3568_RS07050	COG0004	ammonium transporteR
G3568_RS07080	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
G3568_RS07090	COG2363	Small membrane protein
G3568_RS07100	COG2022	thiamine diphosphate biosynthetic process
G3568_RS07105	COG0220	tRNA (guanine-N7-)-methyltransferase activity
G3568_RS07120	COG1999	signal sequence binding
G3568_RS07130	COG0545	Peptidyl-prolyl cis-trans isomerase
G3568_RS07135	COG0589	response to stress
G3568_RS07140	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G3568_RS07145	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
G3568_RS07150	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G3568_RS07160	COG0488	(ABC) transporter
G3568_RS07165	COG1490	D-aminoacyl-tRNA deacylase activity
G3568_RS07175	COG0351	phosphomethylpyrimidine kinase
G3568_RS07180	COG1238	metal cluster binding
G3568_RS07185	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G3568_RS07200	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G3568_RS07210	COG0218	Necessary for normal cell division and for the maintenance of normal septation
G3568_RS07215	COG1011	Hydrolase
G3568_RS07220	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
G3568_RS07235	COG0019	diaminopimelate decarboxylase activity
G3568_RS07245	COG0165	Argininosuccinate lyase
G3568_RS07250	COG0181	hydroxymethylbilane synthase activity
G3568_RS07260	COG2959	enzyme of heme biosynthesis
G3568_RS07270	COG2252	PERMEase
G3568_RS07275	COG0668	transmembrane transport
G3568_RS07285	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
G3568_RS07290	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
G3568_RS07295	COG0189	ligase activity
G3568_RS07295	COG4067	protein conserved in archaea
G3568_RS07305	COG3718	enzyme involved in inositol metabolism
G3568_RS07310	COG0673	inositol 2-dehydrogenase activity
G3568_RS07325	COG4214	carbohydrate transport
G3568_RS07340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G3568_RS07345	COG3962	Belongs to the TPP enzyme family
G3568_RS07375	COG1748	Saccharopine dehydrogenase
G3568_RS07400	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G3568_RS07410	COG1136	(ABC) transporter
G3568_RS07410	COG0577	efflux transmembrane transporter activity
G3568_RS07445	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
G3568_RS07450	COG2867	negative regulation of translational initiation
G3568_RS07460	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G3568_RS07470	COG0497	DNA recombination
G3568_RS07475	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
G3568_RS07480	COG0443	Heat shock 70 kDa protein
G3568_RS07485	COG0484	heat shock protein binding
G3568_RS07490	COG2433	Pfam Transposase IS66
G3568_RS07500	COG2963	transposase activity
G3568_RS07520	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
G3568_RS07545	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
G3568_RS07550	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G3568_RS07555	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
G3568_RS07560	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G3568_RS07565	COG0149	triose-phosphate isomerase activity
G3568_RS07570	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
G3568_RS07585	COG0779	Required for maturation of 30S ribosomal subunits
G3568_RS07590	COG0195	Participates in both transcription termination and antitermination
G3568_RS07595	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
G3568_RS07600	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
G3568_RS07605	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
G3568_RS07610	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
G3568_RS07615	COG1185	polyribonucleotide nucleotidyltransferase activity
G3568_RS07645	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
G3568_RS07650	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
G3568_RS07660	COG0617	tRNA 3'-terminal CCA addition
G3568_RS07670	COG4191	Histidine kinase
G3568_RS07680	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G3568_RS07685	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
G3568_RS07690	COG0436	Aminotransferase
G3568_RS07695	COG1489	DNA binding
G3568_RS07710	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G3568_RS07735	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
G3568_RS07740	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
G3568_RS07770	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G3568_RS07780	COG1902	pentaerythritol trinitrate reductase activity
G3568_RS07790	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
G3568_RS07795	COG0709	Synthesizes selenophosphate from selenide and ATP
G3568_RS07800	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
G3568_RS07805	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G3568_RS07805	COG0519	Catalyzes the synthesis of GMP from XMP
G3568_RS07825	COG0107	imidazoleglycerol-phosphate synthase activity
G3568_RS07830	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
G3568_RS07835	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
G3568_RS07840	COG0131	Imidazoleglycerol-phosphate dehydratase
G3568_RS07855	COG1194	a g-specific adenine glycosylase
G3568_RS07860	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
G3568_RS07915	COG2433	Pfam Transposase IS66
G3568_RS07935	COG5285	phytanoyl-CoA dioxygenase
G3568_RS07940	COG0179	Fumarylacetoacetate (FAA) hydrolase
G3568_RS07945	COG1166	arginine decarboxylase activity
G3568_RS07970	COG0402	S-adenosylhomocysteine deaminase activity
G3568_RS07975	COG2233	PERMEase
G3568_RS07980	COG0583	DNA-binding transcription factor activity
G3568_RS07985	COG3842	ATPase activity
G3568_RS07990	COG1178	ABC-type Fe3 transport system permease component
G3568_RS07995	COG1840	ABC-type Fe3 transport system, periplasmic component
G3568_RS08000	COG1444	tRNA N-acetyltransferase activity
G3568_RS08005	COG2195	Cleaves the N-terminal amino acid of tripeptides
G3568_RS08015	COG0783	Belongs to the Dps family
G3568_RS08020	COG1929	Belongs to the glycerate kinase type-1 family
G3568_RS08085	COG1607	acyl-coa hydrolase
G3568_RS08090	COG2031	fatty acid transporter
G3568_RS08095	COG0534	Mate efflux family protein
G3568_RS08100	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
G3568_RS08105	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
G3568_RS08115	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G3568_RS08130	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
G3568_RS08165	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G3568_RS08170	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
G3568_RS08175	COG4459	periplasmic nitrate reductase
G3568_RS08190	COG0243	molybdopterin cofactor binding
G3568_RS08200	COG3005	denitrification pathway
G3568_RS08210	COG0679	Auxin Efflux Carrier
G3568_RS08220	COG1414	Transcriptional regulator
G3568_RS08225	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
G3568_RS08230	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
G3568_RS08235	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G3568_RS08245	COG0596	Alpha beta hydrolase
G3568_RS08260	COG1819	glycosyl
G3568_RS08270	COG3153	acetyltransferase
G3568_RS08275	COG4453	Protein conserved in bacteria
G3568_RS08295	COG0596	Alpha beta hydrolase
G3568_RS08325	COG0583	DNA-binding transcription factor activity
G3568_RS08335	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G3568_RS08350	COG0583	DNA-binding transcription factor activity
G3568_RS08355	COG2856	Zn peptidase
G3568_RS08365	COG3485	protocatechuate 3,4-dioxygenase
G3568_RS08370	COG3485	protocatechuate 3,4-dioxygenase
G3568_RS08375	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G3568_RS08395	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G3568_RS08410	COG1012	belongs to the aldehyde dehydrogenase family
G3568_RS08435	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G3568_RS08475	COG1012	belongs to the aldehyde dehydrogenase family
G3568_RS08495	COG4948	Mandelate Racemase Muconate Lactonizing
G3568_RS08515	COG1802	Transcriptional regulator
G3568_RS08520	COG1024	Enoyl-CoA hydratase
G3568_RS08530	COG4948	Mandelate Racemase Muconate Lactonizing
G3568_RS08535	COG4829	muconolactone delta-isomerase
G3568_RS08560	COG1028	Short-chain dehydrogenase reductase Sdr
G3568_RS08570	COG3135	benzoate transporter
G3568_RS08580	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
G3568_RS08585	COG1025	Belongs to the peptidase M16 family
G3568_RS08590	COG0535	radical SAM domain protein
G3568_RS08600	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
G3568_RS08645	COG1131	(ABC) transporter
G3568_RS08655	COG3474	cytochrome
G3568_RS08680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G3568_RS08700	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
G3568_RS08705	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3568_RS08705	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3568_RS08715	COG0583	DNA-binding transcription factor activity
G3568_RS08735	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G3568_RS08750	COG2197	response regulator
G3568_RS08760	COG1757	Na H antiporter
G3568_RS08765	COG2957	Belongs to the agmatine deiminase family
G3568_RS08810	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G3568_RS08815	COG3577	Aspartyl protease
G3568_RS08820	COG1295	ribonuclease BN
G3568_RS08845	COG3706	GGDEF domain
G3568_RS08855	COG0494	nUDIX hydrolase
G3568_RS08870	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
G3568_RS08870	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G3568_RS08875	COG0745	RESPONSE REGULATOR receiver
G3568_RS08880	COG2205	protein histidine kinase activity
G3568_RS08885	COG0583	DNA-binding transcription factor activity
G3568_RS08890	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
G3568_RS08905	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
G3568_RS08915	COG1176	ABC-type spermidine putrescine transport system, permease component I
G3568_RS08925	COG3842	ATPase activity
G3568_RS08945	COG0519	Catalyzes the synthesis of GMP from XMP
G3568_RS08955	COG0346	lactoylglutathione lyase activity
G3568_RS08960	COG4221	oxidoreductase activity
G3568_RS08975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G3568_RS08985	COG0765	amino acid transport
G3568_RS08990	COG0765	amino acid transport
G3568_RS09000	COG2259	Doxx family
G3568_RS09010	COG0671	phosphoesterase, PA-phosphatase related
G3568_RS09020	COG1028	Short-chain dehydrogenase reductase Sdr
G3568_RS09025	COG0525	valine-tRNA ligase activity
G3568_RS09035	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G3568_RS09040	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
G3568_RS09045	COG0795	lipopolysaccharide-transporting ATPase activity
G3568_RS09050	COG0795	lipopolysaccharide-transporting ATPase activity
G3568_RS09070	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G3568_RS09075	COG1116	anion transmembrane transporter activity
G3568_RS09080	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3568_RS09090	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
G3568_RS09100	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
G3568_RS09105	COG0406	alpha-ribazole phosphatase activity
G3568_RS09115	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
G3568_RS09130	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G3568_RS09140	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G3568_RS09145	COG0402	S-adenosylhomocysteine deaminase activity
G3568_RS09185	COG0402	S-adenosylhomocysteine deaminase activity
G3568_RS09200	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
G3568_RS09220	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
G3568_RS09230	COG3360	Dodecin
G3568_RS09245	COG0242	peptide deformylase activity
G3568_RS09250	COG1652	LysM domain
G3568_RS09255	COG0758	DNA mediated transformation
G3568_RS09260	COG0009	L-threonylcarbamoyladenylate synthase
G3568_RS09265	COG0408	coproporphyrinogen oxidase activity
G3568_RS09270	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G3568_RS09275	COG2130	NADP-dependent
G3568_RS09285	COG1850	ribulose-bisphosphate carboxylase activity
G3568_RS09295	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
G3568_RS09300	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G3568_RS09305	COG0287	Prephenate dehydrogenase
G3568_RS09310	COG2186	Transcriptional regulator
G3568_RS09320	COG0601	transmembrane transport
G3568_RS09325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G3568_RS09340	COG0501	Belongs to the peptidase M48B family
G3568_RS09360	COG2133	pyrroloquinoline quinone binding
G3568_RS09365	COG1160	GTP binding
G3568_RS09375	COG2976	Protein conserved in bacteria
G3568_RS09380	COG0124	histidyl-tRNA synthetase
G3568_RS09385	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
G3568_RS09400	COG0820	rRNA (adenine-C2-)-methyltransferase activity
G3568_RS09405	COG0105	UTP biosynthetic process
G3568_RS09415	COG1104	cysteine desulfurase activity
G3568_RS09445	COG3263	regulation of cellular component size
G3568_RS09460	COG1862	Preprotein translocase
G3568_RS09465	COG0343	queuine tRNA-ribosyltransferase activity
G3568_RS09470	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
G3568_RS09480	COG0582	viral genome integration into host DNA
G3568_RS09525	COG1454	alcohol dehydrogenase
G3568_RS09530	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
G3568_RS09570	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
G3568_RS09585	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G3568_RS09600	COG0179	Fumarylacetoacetate (FAA) hydrolase
G3568_RS09620	COG4948	Mandelate Racemase Muconate Lactonizing
G3568_RS09655	COG2003	Belongs to the UPF0758 family
G3568_RS09660	COG4691	Plasmid stability protein
G3568_RS09685	COG1061	Type III restriction enzyme res subunit
G3568_RS09690	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
G3568_RS09730	COG1609	Transcriptional regulator
G3568_RS09740	COG0129	dihydroxy-acid dehydratase activity
G3568_RS09745	COG2358	TRAP transporter, solute receptor (TAXI family
G3568_RS09780	COG1737	Transcriptional regulator
G3568_RS09785	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G3568_RS09795	COG1028	Short-chain dehydrogenase reductase Sdr
G3568_RS09800	COG1063	alcohol dehydrogenase
G3568_RS09810	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G3568_RS09815	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G3568_RS09835	COG3038	cytochrome b561
G3568_RS09845	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G3568_RS09860	COG1960	acyl-CoA dehydrogenase activity
G3568_RS09870	COG0714	Associated with various cellular activities
G3568_RS09885	COG0386	Belongs to the glutathione peroxidase family
G3568_RS09895	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
G3568_RS09915	COG2226	methyltransferase
G3568_RS09935	COG1012	belongs to the aldehyde dehydrogenase family
G3568_RS09940	COG3724	N-succinylarginine dihydrolase activity
G3568_RS09975	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
G3568_RS09990	COG2182	Extracellular solute-binding protein
G3568_RS09995	COG1175	transmembrane transport
G3568_RS10000	COG3833	ABC-type maltose transport systems, permease component
G3568_RS10010	COG0366	Alpha amylase catalytic
G3568_RS10015	COG2909	trisaccharide binding
G3568_RS10025	COG0149	triose-phosphate isomerase activity
G3568_RS10030	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
G3568_RS10035	COG1172	Belongs to the binding-protein-dependent transport system permease family
G3568_RS10040	COG1129	ABC transporter
G3568_RS10050	COG1879	ABC-type sugar transport system periplasmic component
G3568_RS10055	COG1028	Short-chain dehydrogenase reductase Sdr
G3568_RS10070	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
G3568_RS10075	COG3958	Transketolase
G3568_RS10080	COG3959	Transketolase, thiamine diphosphate binding domain
G3568_RS10115	COG2382	esterase
G3568_RS10125	COG0840	transmembrane signaling receptor activity
G3568_RS10130	COG0598	Magnesium transport protein CorA
G3568_RS10145	COG1028	Short-chain dehydrogenase reductase Sdr
G3568_RS10175	COG1063	alcohol dehydrogenase
G3568_RS10180	COG3938	Belongs to the proline racemase family
G3568_RS10190	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
G3568_RS10215	COG1902	pentaerythritol trinitrate reductase activity
G3568_RS10235	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G3568_RS10260	COG0778	Nitroreductase
G3568_RS10265	COG2207	Transcriptional regulator
G3568_RS10305	COG1917	Cupin 2, conserved barrel domain protein
G3568_RS10305	COG2207	Transcriptional regulator
G3568_RS10330	COG1028	Short-chain dehydrogenase reductase Sdr
G3568_RS10335	COG0583	DNA-binding transcription factor activity
G3568_RS10355	COG4948	Mandelate Racemase Muconate Lactonizing
G3568_RS10375	COG1609	Transcriptional regulator
G3568_RS10405	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G3568_RS10420	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
G3568_RS10430	COG0384	phenazine biosynthesis protein PhzF
G3568_RS10485	COG1595	DNA-templated transcription, initiation
G3568_RS10510	COG1595	DNA-templated transcription, initiation
G3568_RS10520	COG4774	siderophore transport
G3568_RS10530	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G3568_RS10535	COG1120	ATPase activity
G3568_RS10545	COG1132	(ABC) transporter
G3568_RS10585	COG2032	superoxide dismutase activity
G3568_RS10630	COG0662	Cupin 2, conserved barrel domain protein
G3568_RS10635	COG5654	RES domain protein
G3568_RS10650	COG1132	(ABC) transporter
G3568_RS10660	COG1802	Transcriptional regulator
G3568_RS10695	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G3568_RS10700	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G3568_RS10720	COG3257	ureidoglycine aminohydrolase activity
G3568_RS10745	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
G3568_RS10755	COG2826	transposase and inactivated derivatives, IS30 family
G3568_RS10775	COG4608	Belongs to the ABC transporter superfamily
G3568_RS10780	COG0444	Belongs to the ABC transporter superfamily
G3568_RS10790	COG0601	transmembrane transport
G3568_RS10795	COG0747	negative chemotaxis
G3568_RS10800	COG0583	DNA-binding transcription factor activity
G3568_RS10815	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G3568_RS10820	COG1074	ATP-dependent DNA helicase activity
G3568_RS10825	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
G3568_RS10870	COG5642	Protein of unknown function (DUF2384)
G3568_RS10880	COG0583	DNA-binding transcription factor activity
G3568_RS10890	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
G3568_RS10895	COG1595	DNA-templated transcription, initiation
G3568_RS10910	COG1487	ribonuclease activity
G3568_RS10925	COG4206	TonB-dependent receptor
G3568_RS10925	COG1629	transport
G3568_RS10965	COG2832	Protein of unknown function (DUF454)
G3568_RS10980	COG4221	oxidoreductase activity
G3568_RS10985	COG2207	Transcriptional regulator
G3568_RS11000	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
G3568_RS11005	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G3568_RS11015	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G3568_RS11055	COG0129	dihydroxy-acid dehydratase activity
G3568_RS11060	COG3639	organic phosphonate transmembrane transporter activity
G3568_RS11070	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
G3568_RS11105	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
G3568_RS11135	COG2105	PFAM AIG2 family protein
G3568_RS11140	COG0583	DNA-binding transcription factor activity
G3568_RS11160	COG0174	glutamine synthetase
G3568_RS11165	COG1012	belongs to the aldehyde dehydrogenase family
G3568_RS11175	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G3568_RS11175	COG0519	Catalyzes the synthesis of GMP from XMP
G3568_RS11190	COG0789	Transcriptional regulator
G3568_RS11195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G3568_RS11200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G3568_RS11205	COG4160	amino acid transport
G3568_RS11225	COG0655	NAD(P)H dehydrogenase (quinone) activity
G3568_RS11230	COG0473	3-isopropylmalate dehydrogenase activity
G3568_RS11235	COG0583	DNA-binding transcription factor activity
G3568_RS11255	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
G3568_RS11265	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G3568_RS11265	COG3153	acetyltransferase
G3568_RS11275	COG1653	transport
G3568_RS11285	COG0395	ABC-type sugar transport system, permease component
G3568_RS11290	COG0583	DNA-binding transcription factor activity
G3568_RS11295	COG3842	ATPase activity
G3568_RS11320	COG1177	transmembrane transport
G3568_RS11340	COG2721	sulfolactate sulfo-lyase activity
G3568_RS11355	COG3181	Tripartite tricarboxylate transporter family receptor
G3568_RS11380	COG0697	spore germination
G3568_RS11385	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
G3568_RS11390	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
G3568_RS11395	COG3119	arylsulfatase activity
G3568_RS11400	COG0583	DNA-binding transcription factor activity
G3568_RS11405	COG3193	protein, possibly involved in utilization of glycolate and propanediol
G3568_RS11410	COG0247	lactate metabolic process
G3568_RS11415	COG0277	FAD linked oxidase domain protein
G3568_RS11420	COG0277	FAD linked oxidase domain protein
G3568_RS11425	COG2186	Transcriptional regulator
G3568_RS11430	COG1802	Transcriptional regulator
G3568_RS11440	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G3568_RS11455	COG1024	Enoyl-CoA hydratase
G3568_RS11465	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
G3568_RS11470	COG0247	lactate metabolic process
G3568_RS11470	COG0277	FAD linked oxidase domain protein
G3568_RS11475	COG3618	amidohydrolase
G3568_RS11485	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G3568_RS11495	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G3568_RS11505	COG4948	Mandelate Racemase Muconate Lactonizing
G3568_RS11530	COG1802	Transcriptional regulator
G3568_RS11535	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G3568_RS11555	COG4948	Mandelate Racemase Muconate Lactonizing
G3568_RS11560	COG1063	alcohol dehydrogenase
G3568_RS11565	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G3568_RS11570	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
G3568_RS11575	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G3568_RS11580	COG0246	Mannitol dehydrogenase
G3568_RS11585	COG1312	Catalyzes the dehydration of D-mannonate
G3568_RS11590	COG4145	pantothenate transmembrane transporter activity
G3568_RS11600	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
G3568_RS11605	COG1737	Transcriptional regulator
G3568_RS11615	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G3568_RS11620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G3568_RS11645	COG0390	transport system, permease component
G3568_RS11650	COG3842	ATPase activity
G3568_RS11665	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
G3568_RS11685	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G3568_RS11705	COG1509	lysine 2,3-aminomutase activity
G3568_RS11735	COG0446	pyridine nucleotide-disulphide oxidoreductase
G3568_RS11740	COG2863	cytochrome
G3568_RS11790	COG1609	Transcriptional regulator
G3568_RS11795	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
G3568_RS11795	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G3568_RS11800	COG1105	Belongs to the carbohydrate kinase PfkB family
G3568_RS11830	COG2205	protein histidine kinase activity
G3568_RS11830	COG0784	Response regulator, receiver
G3568_RS11835	COG2133	pyrroloquinoline quinone binding
G3568_RS11845	COG1012	belongs to the aldehyde dehydrogenase family
G3568_RS11850	COG0659	secondary active sulfate transmembrane transporter activity
G3568_RS11855	COG1376	ErfK ybiS ycfS ynhG family protein
G3568_RS11860	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
G3568_RS11865	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
G3568_RS11885	COG0745	RESPONSE REGULATOR receiver
G3568_RS11895	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G3568_RS11905	COG1609	Transcriptional regulator
G3568_RS11910	COG3842	ATPase activity
G3568_RS11915	COG0366	Alpha amylase catalytic
G3568_RS11930	COG1653	transport
G3568_RS11935	COG2431	L-lysine efflux transmembrane transporter activity
G3568_RS11950	COG1335	isochorismatase
G3568_RS11955	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G3568_RS11960	COG0006	proline dipeptidase activity
G3568_RS11965	COG3608	succinylglutamate desuccinylase aspartoacylase
G3568_RS11970	COG1522	sequence-specific DNA binding
G3568_RS11995	COG1012	belongs to the aldehyde dehydrogenase family
G3568_RS12000	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G3568_RS12015	COG4136	ATPase activity
G3568_RS12020	COG4135	transport system, permease component
G3568_RS12025	COG4134	Bacterial extracellular solute-binding protein
G3568_RS12030	COG1030	water channel activity
G3568_RS12040	COG0659	secondary active sulfate transmembrane transporter activity
G3568_RS12045	COG0589	response to stress
G3568_RS12070	COG1737	Transcriptional regulator
G3568_RS12090	COG0583	DNA-binding transcription factor activity
G3568_RS12095	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G3568_RS12120	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
G3568_RS12125	COG1053	succinate dehydrogenase
G3568_RS12160	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
G3568_RS12170	COG3706	GGDEF domain
G3568_RS12195	COG0702	epimerase
G3568_RS12205	COG0745	RESPONSE REGULATOR receiver
G3568_RS12220	COG1175	transmembrane transport
G3568_RS12225	COG0395	ABC-type sugar transport system, permease component
G3568_RS12230	COG3842	ATPase activity
G3568_RS12240	COG3768	UPF0283 membrane protein
G3568_RS12245	COG3106	COG3106 Predicted ATPase
G3568_RS12250	COG2814	Major facilitator Superfamily
G3568_RS12255	COG4977	sequence-specific DNA binding
G3568_RS12260	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G3568_RS12290	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
G3568_RS12305	COG0791	NLP P60 protein
G3568_RS12310	COG0583	DNA-binding transcription factor activity
G3568_RS12315	COG2814	Major facilitator Superfamily
G3568_RS12320	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G3568_RS12325	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G3568_RS12330	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
G3568_RS12340	COG0444	Belongs to the ABC transporter superfamily
G3568_RS12345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G3568_RS12360	COG0864	Transcriptional regulator
G3568_RS12365	COG1047	Peptidyl-prolyl cis-trans
G3568_RS12390	COG2850	peptidyl-arginine hydroxylation
G3568_RS12400	COG2915	High frequency lysogenization protein hflD homolog
G3568_RS12405	COG0482	sulfurtransferase activity
G3568_RS12420	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G3568_RS12430	COG1187	pseudouridine synthase activity
G3568_RS12440	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
G3568_RS12445	COG0542	response to heat
G3568_RS12450	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
G3568_RS12455	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
G3568_RS12460	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
G3568_RS12465	COG1674	ftsk spoiiie
G3568_RS12470	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
G3568_RS12475	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
G3568_RS12485	COG0583	DNA-binding transcription factor activity
G3568_RS12490	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
G3568_RS12495	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G3568_RS12500	COG2902	Dehydrogenase
G3568_RS12505	COG0167	dihydroorotate dehydrogenase activity
G3568_RS12510	COG3130	regulation of translation
G3568_RS12515	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
G3568_RS12515	COG0116	Belongs to the methyltransferase superfamily
G3568_RS12535	COG0673	inositol 2-dehydrogenase activity
G3568_RS12550	COG3181	Tripartite tricarboxylate transporter family receptor
G3568_RS12580	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G3568_RS12585	COG0501	Belongs to the peptidase M48B family
G3568_RS12590	COG0436	Aminotransferase
G3568_RS12595	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
G3568_RS12600	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G3568_RS12635	COG1131	(ABC) transporter
G3568_RS12640	COG0842	Transport permease protein
G3568_RS12645	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
G3568_RS12645	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
G3568_RS12690	COG2217	Heavy metal translocating P-type atpase
G3568_RS12710	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G3568_RS12715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G3568_RS12720	COG2081	HI0933 family
G3568_RS12735	COG4575	ribosome binding
G3568_RS12745	COG1196	nuclear chromosome segregation
G3568_RS12745	COG3264	Mechanosensitive ion channel
G3568_RS12755	COG1335	isochorismatase
G3568_RS12765	COG0583	DNA-binding transcription factor activity
G3568_RS12770	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
G3568_RS12795	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
G3568_RS12800	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
G3568_RS12805	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
G3568_RS12815	COG3100	YcgL domain-containing protein
G3568_RS12820	COG2983	Belongs to the UPF0260 family
G3568_RS12830	COG1770	oligopeptidase
G3568_RS12845	COG0121	glutamine amidotransferase
G3568_RS12850	COG0318	PFAM AMP-dependent synthetase and ligase
G3568_RS12855	COG1643	Atp-dependent helicase
G3568_RS12865	COG2853	Lipoprotein
G3568_RS12880	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
G3568_RS12885	COG2814	Major facilitator Superfamily
G3568_RS12900	COG0573	inorganic phosphate transmembrane transporter activity
G3568_RS12910	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G3568_RS12915	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G3568_RS12925	COG0640	Transcriptional regulator
G3568_RS12940	COG0640	Transcriptional regulator
G3568_RS12945	COG1047	Peptidyl-prolyl cis-trans
G3568_RS12960	COG0437	4 iron, 4 sulfur cluster binding
G3568_RS12965	COG0243	molybdopterin cofactor binding
G3568_RS12980	COG0798	PFAM Bile acid sodium symporter
G3568_RS12985	COG0183	Belongs to the thiolase family
G3568_RS12990	COG1309	transcriptional regulator
G3568_RS12995	COG1960	acyl-CoA dehydrogenase activity
G3568_RS13000	COG3384	dioxygenase
G3568_RS13005	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G3568_RS13010	COG1321	iron dependent repressor
G3568_RS13010	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G3568_RS13015	COG1121	(ABC) transporter
G3568_RS13020	COG0803	Belongs to the bacterial solute-binding protein 9 family
G3568_RS13025	COG2832	Protein of unknown function (DUF454)
G3568_RS13030	COG0308	aminopeptidase N
G3568_RS13040	COG1704	LemA family
G3568_RS13045	COG0501	Belongs to the peptidase M48B family
G3568_RS13050	COG1597	lipid kinase activity
G3568_RS13060	COG1278	Cold shock
G3568_RS13065	COG1280	lysine exporter protein (LysE YggA)
G3568_RS13070	COG0741	lytic transglycosylase activity
G3568_RS13085	COG0326	Molecular chaperone. Has ATPase activity
G3568_RS13090	COG1335	isochorismatase
G3568_RS13100	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
G3568_RS13105	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
G3568_RS13110	COG2062	phosphohistidine phosphatase, SixA
G3568_RS13140	COG2721	sulfolactate sulfo-lyase activity
G3568_RS13145	COG4948	Mandelate Racemase Muconate Lactonizing
G3568_RS13150	COG2186	Transcriptional regulator
G3568_RS13170	COG0596	Alpha beta hydrolase
G3568_RS13190	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
G3568_RS13205	COG3243	poly(R)-hydroxyalkanoic acid synthase
G3568_RS13215	COG4535	Mg2 and Co2 transporter CorC
G3568_RS13220	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
G3568_RS13225	COG1702	phosphate starvation-inducible protein PhoH
G3568_RS13230	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G3568_RS13240	COG4991	sh3 domain protein
G3568_RS13245	COG0500	methyltransferase
G3568_RS13255	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
G3568_RS13260	COG4208	sulfate ABC transporter
G3568_RS13270	COG4150	thiosulfate binding
G3568_RS13285	COG2827	Endonuclease containing a URI domain
G3568_RS13290	COG0668	transmembrane transport
G3568_RS13295	COG1252	NADH dehydrogenase
G3568_RS13300	COG0546	phosphoglycolate phosphatase activity
G3568_RS13315	COG3501	Rhs element vgr protein
G3568_RS13360	COG3549	Plasmid maintenance system killer
G3568_RS13380	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G3568_RS13385	COG0134	indole-3-glycerol-phosphate synthase activity
G3568_RS13455	COG1192	Involved in chromosome partitioning
G3568_RS13480	COG3344	reverse transcriptase
G3568_RS13570	COG0454	-acetyltransferase
G3568_RS13580	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
G3568_RS13605	COG1917	Cupin 2, conserved barrel domain protein
G3568_RS13610	COG0456	acetyltransferase
G3568_RS13615	COG0583	DNA-binding transcription factor activity
G3568_RS13645	COG0247	lactate metabolic process
G3568_RS13645	COG0277	FAD linked oxidase domain protein
G3568_RS13650	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
G3568_RS13660	COG0628	permease
G3568_RS13675	COG0175	sulfate reduction
G3568_RS13685	COG1802	Transcriptional regulator
G3568_RS13690	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
G3568_RS13695	COG0372	Belongs to the citrate synthase family
G3568_RS13705	COG2828	Protein conserved in bacteria
G3568_RS13720	COG1132	(ABC) transporter
G3568_RS13760	COG2267	carboxylic ester hydrolase activity
G3568_RS13765	COG2130	NADP-dependent
G3568_RS13785	COG1028	Short-chain dehydrogenase reductase Sdr
G3568_RS13820	COG1396	sequence-specific DNA binding
G3568_RS13830	COG0604	alcohol dehydrogenase
G3568_RS13850	COG0456	acetyltransferase
G3568_RS13850	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
G3568_RS13865	COG1794	racemase activity, acting on amino acids and derivatives
G3568_RS13885	COG0640	Transcriptional regulator
G3568_RS13900	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
G3568_RS13910	COG0778	Nitroreductase
G3568_RS13920	COG1846	Transcriptional regulator
G3568_RS13935	COG0583	DNA-binding transcription factor activity
G3568_RS13940	COG5285	phytanoyl-CoA dioxygenase
G3568_RS13960	COG0384	phenazine biosynthesis protein PhzF
G3568_RS13985	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G3568_RS14000	COG1522	sequence-specific DNA binding
G3568_RS14025	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
G3568_RS14040	COG0583	DNA-binding transcription factor activity
G3568_RS14045	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
G3568_RS14050	COG0583	DNA-binding transcription factor activity
G3568_RS14055	COG1595	DNA-templated transcription, initiation
G3568_RS14065	COG2764	glyoxalase bleomycin resistance protein dioxygenase
G3568_RS14100	COG1028	Short-chain dehydrogenase reductase Sdr
G3568_RS14105	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
G3568_RS14105	COG2169	Transcriptional regulator
G3568_RS14130	COG0477	Major facilitator Superfamily
G3568_RS14135	COG1309	transcriptional regulator
G3568_RS14140	COG1028	Short-chain dehydrogenase reductase Sdr
G3568_RS14145	COG0563	adenylate kinase activity
G3568_RS14150	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
G3568_RS14155	COG0583	DNA-binding transcription factor activity
G3568_RS14165	COG1280	lysine exporter protein (LysE YggA)
G3568_RS14175	COG3795	YCII-related domain
G3568_RS14180	COG4941	Belongs to the sigma-70 factor family
G3568_RS14185	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
G3568_RS14195	COG1362	aminopeptidase activity
G3568_RS14200	COG0583	DNA-binding transcription factor activity
G3568_RS14215	COG0012	GTP binding
G3568_RS14220	COG0193	aminoacyl-tRNA hydrolase activity
G3568_RS14225	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
G3568_RS14240	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
G3568_RS14245	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
G3568_RS14255	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
G3568_RS14260	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
G3568_RS14265	COG2890	protein-(glutamine-N5) methyltransferase activity
G3568_RS14285	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G3568_RS14290	COG0174	glutamine synthetase
G3568_RS14300	COG3842	ATPase activity
G3568_RS14305	COG1176	ABC-type spermidine putrescine transport system, permease component I
G3568_RS14310	COG1177	transmembrane transport
G3568_RS14315	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G3568_RS14320	COG2759	Belongs to the formate--tetrahydrofolate ligase family
G3568_RS14330	COG0404	The glycine cleavage system catalyzes the degradation of glycine
G3568_RS14335	COG0404	The glycine cleavage system catalyzes the degradation of glycine
G3568_RS14350	COG0174	glutamine synthetase
G3568_RS14355	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
G3568_RS14365	COG1012	belongs to the aldehyde dehydrogenase family
G3568_RS14370	COG1322	Protein conserved in bacteria
G3568_RS14380	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G3568_RS14385	COG0154	amidase activity
G3568_RS14390	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G3568_RS14395	COG1077	Cell shape determining protein MreB Mrl
G3568_RS14400	COG1792	Involved in formation and maintenance of cell shape
G3568_RS14405	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
G3568_RS14410	COG0424	maF-like protein
G3568_RS14415	COG1530	ribonuclease E activity
G3568_RS14430	COG0312	modulator of DNA gyrase
G3568_RS14445	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G3568_RS14450	COG1660	Displays ATPase and GTPase activities
G3568_RS14470	COG1137	ATPase activity
G3568_RS14475	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
G3568_RS14495	COG0530	calcium, potassium:sodium antiporter activity
G3568_RS14500	COG1127	ABC transporter
G3568_RS14505	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G3568_RS14510	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G3568_RS14530	COG5007	Belongs to the BolA IbaG family
G3568_RS14535	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
G3568_RS14540	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
G3568_RS14550	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G3568_RS14565	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
G3568_RS14570	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
G3568_RS14575	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
G3568_RS14580	COG0723	plastoquinol--plastocyanin reductase activity
G3568_RS14585	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
G3568_RS14590	COG2857	Cytochrome c1
G3568_RS14595	COG0625	glutathione transferase activity
G3568_RS14600	COG2969	positive regulation of protein catabolic process
G3568_RS14605	COG2823	Periplasmic or secreted lipoprotein
G3568_RS14610	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
G3568_RS14615	COG0792	nuclease activity
G3568_RS14635	COG0275	rRNA processing
G3568_RS14640	COG3116	cell division
G3568_RS14655	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
G3568_RS14660	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G3568_RS14665	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
G3568_RS14670	COG0772	Belongs to the SEDS family
G3568_RS14675	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
G3568_RS14680	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G3568_RS14685	COG1181	Belongs to the D-alanine--D-alanine ligase family
G3568_RS14705	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
G3568_RS14725	COG0352	thiamine-phosphate diphosphorylase activity
G3568_RS14730	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G3568_RS14735	COG2957	Belongs to the agmatine deiminase family
G3568_RS14740	COG4591	ABC-type transport system involved in lipoprotein release permease component
G3568_RS14745	COG1136	(ABC) transporter
G3568_RS14760	COG1132	(ABC) transporter
G3568_RS14765	COG1663	tetraacyldisaccharide 4'-kinase activity
G3568_RS14770	COG2835	tetraacyldisaccharide 4'-kinase activity
G3568_RS14775	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
G3568_RS14780	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G3568_RS14785	COG0812	UDP-N-acetylmuramate dehydrogenase activity
G3568_RS14790	COG1530	ribonuclease E activity
G3568_RS14795	COG0564	pseudouridine synthase activity
G3568_RS14805	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G3568_RS14805	COG0616	signal peptide processing
G3568_RS14810	COG0424	maF-like protein
G3568_RS14815	COG1399	metal-binding, possibly nucleic acid-binding protein
G3568_RS14820	COG0333	Belongs to the bacterial ribosomal protein bL32 family
G3568_RS14825	COG0416	fatty acid biosynthetic process
G3568_RS14830	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
G3568_RS14840	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G3568_RS14845	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G3568_RS14855	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
G3568_RS14860	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
G3568_RS14875	COG0084	hydrolase, TatD family'
G3568_RS14885	COG0210	DNA helicase
G3568_RS14920	COG4771	TonB-dependent receptor
G3568_RS14925	COG0583	DNA-binding transcription factor activity
G3568_RS14930	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G3568_RS14935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G3568_RS14940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G3568_RS14945	COG1120	ATPase activity
G3568_RS14955	COG0811	peptide transport
G3568_RS14960	COG0811	peptide transport
G3568_RS14965	COG0848	biopolymer transport protein
G3568_RS14990	COG0513	Belongs to the DEAD box helicase family
G3568_RS14995	COG1199	ATP-dependent helicase activity
G3568_RS15000	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G3568_RS15025	COG0481	GTPase activity
G3568_RS15030	COG0681	Belongs to the peptidase S26 family
G3568_RS15035	COG0571	ribonuclease III activity
G3568_RS15040	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
G3568_RS15045	COG1381	Involved in DNA repair and RecF pathway recombination
G3568_RS15060	COG5002	protein histidine kinase activity
G3568_RS15060	COG0784	Response regulator, receiver
G3568_RS15060	COG2205	protein histidine kinase activity
G3568_RS15070	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G3568_RS15075	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G3568_RS15080	COG3956	TIGRFAM MazG family protein
G3568_RS15085	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
G3568_RS15095	COG0745	RESPONSE REGULATOR receiver
G3568_RS15100	COG0642	Histidine kinase
G3568_RS15105	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G3568_RS15110	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G3568_RS15115	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
G3568_RS15120	COG0653	protein targeting
G3568_RS15125	COG2211	Major facilitator Superfamily
G3568_RS15135	COG1047	Peptidyl-prolyl cis-trans
G3568_RS15160	COG0741	lytic transglycosylase activity
G3568_RS15165	COG0442	prolyl-tRNA aminoacylation
G3568_RS15180	COG3023	N-Acetylmuramoyl-L-alanine amidase
G3568_RS15200	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G3568_RS15205	COG2084	Dehydrogenase
G3568_RS15225	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
G3568_RS15230	COG1132	(ABC) transporter
G3568_RS15260	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G3568_RS15270	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G3568_RS15280	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G3568_RS15285	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
G3568_RS15290	COG1609	Transcriptional regulator
G3568_RS15300	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
G3568_RS15320	COG3038	cytochrome b561
G3568_RS15325	COG2353	YceI-like domain
G3568_RS15340	COG0534	Mate efflux family protein
G3568_RS15355	COG2154	pterin-4-alpha-carbinolamine dehydratase
G3568_RS15375	COG0514	ATP-dependent DNA helicase (RecQ)
G3568_RS15410	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G3568_RS15425	COG1279	arginine transmembrane transporter activity
G3568_RS15440	COG0625	glutathione transferase activity
G3568_RS15460	COG0733	neurotransmitter:sodium symporter activity
G3568_RS15465	COG1648	precorrin-2 dehydrogenase activity
G3568_RS15465	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G3568_RS15470	COG3290	protein histidine kinase activity
G3568_RS15475	COG4565	transcriptional regulatory protein
G3568_RS15495	COG1960	acyl-CoA dehydrogenase activity
G3568_RS15525	COG0829	nickel cation binding
G3568_RS15530	COG0831	urea catabolic process
G3568_RS15535	COG0832	Belongs to the urease beta subunit family
G3568_RS15540	COG0804	urea catabolic process
G3568_RS15545	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
G3568_RS15550	COG0830	nickel cation binding
G3568_RS15555	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
G3568_RS15560	COG3706	GGDEF domain
G3568_RS15575	COG0038	chloride channel
G3568_RS15585	COG5507	3-demethylubiquinone-9 3-methyltransferase
G3568_RS15590	COG0840	transmembrane signaling receptor activity
G3568_RS15605	COG2207	Transcriptional regulator
G3568_RS15605	COG1917	Cupin 2, conserved barrel domain protein
G3568_RS15610	COG1280	lysine exporter protein (LysE YggA)
G3568_RS15615	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
G3568_RS15615	COG0069	glutamate synthase activity
G3568_RS15635	COG1944	ATP diphosphatase activity
G3568_RS15640	COG0625	glutathione transferase activity
G3568_RS15655	COG0583	DNA-binding transcription factor activity
G3568_RS15665	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G3568_RS15680	COG1231	oxidoreductase activity
G3568_RS15715	COG3153	acetyltransferase
G3568_RS15725	COG2249	NAD(P)H dehydrogenase (quinone) activity
G3568_RS15735	COG3214	Protein conserved in bacteria
G3568_RS15755	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G3568_RS15760	COG1960	acyl-CoA dehydrogenase activity
G3568_RS15765	COG2226	methyltransferase
G3568_RS15800	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G3568_RS15820	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G3568_RS15830	COG4172	Belongs to the ABC transporter superfamily
G3568_RS15835	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G3568_RS15840	COG0601	transmembrane transport
G3568_RS15845	COG0747	negative chemotaxis
G3568_RS15855	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G3568_RS15865	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3568_RS15870	COG4221	oxidoreductase activity
G3568_RS15875	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G3568_RS15895	COG0251	oxidation-reduction process
G3568_RS15900	COG2423	ornithine cyclodeaminase activity
G3568_RS15945	COG0459	protein refolding
G3568_RS15950	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
G3568_RS15960	COG1028	Short-chain dehydrogenase reductase Sdr
G3568_RS15970	COG0284	orotidine-5'-phosphate decarboxylase activity
G3568_RS15975	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
G3568_RS15985	COG0776	regulation of translation
G3568_RS16000	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
G3568_RS16030	COG2197	response regulator
G3568_RS16040	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
G3568_RS16045	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
G3568_RS16050	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
G3568_RS16055	COG0137	argininosuccinate synthase activity
G3568_RS16075	COG5002	protein histidine kinase activity
G3568_RS16090	COG0745	RESPONSE REGULATOR receiver
G3568_RS16105	COG1966	Carbon starvation protein
G3568_RS16115	COG0003	Pfam Anion-transporting ATPase
G3568_RS16125	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
G3568_RS16130	COG2878	Part of a membrane complex involved in electron transport
G3568_RS16135	COG2203	Gaf domain
G3568_RS16135	COG4251	negative regulation of phosphorylation
G3568_RS16135	COG3706	GGDEF domain
G3568_RS16135	COG5001	Diguanylate cyclase
G3568_RS16140	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G3568_RS16140	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G3568_RS16150	COG0417	DNA replication proofreading
G3568_RS16165	COG0625	glutathione transferase activity
G3568_RS16190	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G3568_RS16200	COG1131	(ABC) transporter
G3568_RS16205	COG0842	Transport permease protein
G3568_RS16235	COG1959	2 iron, 2 sulfur cluster binding
G3568_RS16235	COG1295	ribonuclease BN
G3568_RS16260	COG0489	protein tyrosine kinase activity
G3568_RS16265	COG0717	Belongs to the dCTP deaminase family
G3568_RS16270	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
G3568_RS16275	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
G3568_RS16280	COG0628	permease
G3568_RS16285	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
G3568_RS16300	COG1349	DNA-binding transcription factor activity
G3568_RS16305	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
G3568_RS16320	COG1956	GAF domain-containing protein
G3568_RS16325	COG1464	Belongs to the NlpA lipoprotein family
G3568_RS16330	COG2011	ABC-type metal ion transport system permease component
G3568_RS16335	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
G3568_RS16340	COG0307	riboflavin synthase, alpha
G3568_RS16345	COG2252	PERMEase
G3568_RS16350	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
G3568_RS16355	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
G3568_RS16360	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
G3568_RS16365	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
G3568_RS16375	COG1917	Cupin 2, conserved barrel domain protein
G3568_RS16375	COG1396	sequence-specific DNA binding
G3568_RS16380	COG0746	molybdenum cofactor guanylyltransferase activity
G3568_RS16385	COG1763	Mo-molybdopterin cofactor biosynthetic process
G3568_RS16395	COG0315	cyclic pyranopterin monophosphate synthase activity
G3568_RS16405	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
G3568_RS16430	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G3568_RS16435	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
G3568_RS16440	COG1309	transcriptional regulator
G3568_RS16465	COG1024	Enoyl-CoA hydratase
G3568_RS16465	COG1250	3-hydroxyacyl-CoA dehydrogenase
G3568_RS16470	COG1960	acyl-CoA dehydrogenase activity
G3568_RS16475	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3568_RS16480	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
G3568_RS16490	COG0405	Gamma-glutamyltransferase
G3568_RS16495	COG0584	glycerophosphoryl diester phosphodiesterase
G3568_RS16500	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G3568_RS16535	COG0602	queuosine metabolic process
G3568_RS16540	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
G3568_RS16565	COG3706	GGDEF domain
G3568_RS16570	COG3418	PFAM FlgN family protein
G3568_RS16575	COG2747	anti-sigma28 factor FlgM
G3568_RS16585	COG1815	bacterial-type flagellum-dependent cell motility
G3568_RS16590	COG1558	bacterial-type flagellum-dependent cell motility
G3568_RS16595	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
G3568_RS16605	COG4787	bacterial-type flagellum-dependent cell motility
G3568_RS16615	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
G3568_RS16620	COG1706	bacterial-type flagellum-dependent cell motility
G3568_RS16625	COG1705	Flagellar rod assembly protein muramidase FlgJ
G3568_RS16625	COG3951	Flagellar rod assembly protein muramidase FlgJ
G3568_RS16640	COG0583	DNA-binding transcription factor activity
G3568_RS16660	COG5383	Protein conserved in bacteria
G3568_RS16670	COG1987	bacterial-type flagellum assembly
G3568_RS16675	COG1338	Plays a role in the flagellum-specific transport system
G3568_RS16690	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
G3568_RS16695	COG1580	Controls the rotational direction of flagella during chemotaxis
G3568_RS16725	COG1766	The M ring may be actively involved in energy transduction
G3568_RS16730	COG1677	Flagellar hook-basal body complex protein FliE
G3568_RS16740	COG0252	asparaginase activity
G3568_RS16745	COG1334	flagellar protein FlaG
G3568_RS16750	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
G3568_RS16755	COG1854	S-ribosylhomocysteine lyase activity
G3568_RS16760	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
G3568_RS16785	COG0544	peptidyl-prolyl cis-trans isomerase activity
G3568_RS16790	COG0740	serine-type endopeptidase activity
G3568_RS16795	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
G3568_RS16800	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
G3568_RS16810	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G3568_RS16820	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G3568_RS16825	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
G3568_RS16830	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G3568_RS16835	COG0215	cysteine-tRNA ligase activity
G3568_RS16845	COG4251	negative regulation of phosphorylation
G3568_RS16845	COG3706	GGDEF domain
G3568_RS16845	COG5001	Diguanylate cyclase
G3568_RS16845	COG2203	Gaf domain
G3568_RS16870	COG1732	Glycine betaine
G3568_RS16875	COG1174	glycine betaine transport
G3568_RS16880	COG1125	glycine betaine transport
G3568_RS16885	COG1174	glycine betaine transport
G3568_RS16895	COG0022	dehydrogenase e1 component
G3568_RS16915	COG1802	Transcriptional regulator
G3568_RS16920	COG0579	oxidoreductase
G3568_RS16925	COG0659	secondary active sulfate transmembrane transporter activity
G3568_RS16930	COG1363	Peptidase, m42
G3568_RS16935	COG4993	Dehydrogenase
G3568_RS16940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G3568_RS16945	COG4608	Belongs to the ABC transporter superfamily
G3568_RS16950	COG0444	Belongs to the ABC transporter superfamily
G3568_RS16960	COG0747	negative chemotaxis
G3568_RS16980	COG0840	transmembrane signaling receptor activity
G3568_RS16985	COG3300	MHYT domain
G3568_RS16985	COG5001	Diguanylate cyclase
G3568_RS16995	COG2962	Rard protein
G3568_RS17005	COG1187	pseudouridine synthase activity
G3568_RS17035	COG4172	Belongs to the ABC transporter superfamily
G3568_RS17045	COG4174	ABC transporter (Permease)
G3568_RS17050	COG4166	transmembrane transport
G3568_RS17060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G3568_RS17070	COG0328	RNA-DNA hybrid ribonuclease activity
G3568_RS17080	COG2816	NAD+ diphosphatase activity
G3568_RS17090	COG0616	signal peptide processing
G3568_RS17095	COG0640	Transcriptional regulator
G3568_RS17105	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
G3568_RS17110	COG0596	Alpha beta hydrolase
G3568_RS17115	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G3568_RS17120	COG3263	regulation of cellular component size
G3568_RS17145	COG1346	cytolysis
G3568_RS17160	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
G3568_RS17165	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G3568_RS17170	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
G3568_RS17175	COG1845	cytochrome c oxidase, subunit III
G3568_RS17200	COG0109	protoheme IX farnesyltransferase activity
G3568_RS17215	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
G3568_RS17220	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
G3568_RS17225	COG0291	Belongs to the bacterial ribosomal protein bL35 family
G3568_RS17230	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
G3568_RS17235	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
G3568_RS17240	COG0072	phenylalanine-tRNA ligase activity
G3568_RS17245	COG0776	regulation of translation
G3568_RS17255	COG0716	FMN binding
G3568_RS17265	COG1611	Belongs to the LOG family
G3568_RS17270	COG0583	DNA-binding transcription factor activity
G3568_RS17280	COG0509	glycine decarboxylation via glycine cleavage system
G3568_RS17285	COG1115	amino acid carrier protein
G3568_RS17290	COG0404	The glycine cleavage system catalyzes the degradation of glycine
G3568_RS17300	COG0671	phosphoesterase, PA-phosphatase related
G3568_RS17340	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
G3568_RS17345	COG2205	protein histidine kinase activity
G3568_RS17355	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
G3568_RS17380	COG0556	nucleotide-excision repair
G3568_RS17385	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
G3568_RS17395	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G3568_RS17400	COG0583	DNA-binding transcription factor activity
G3568_RS17405	COG1056	cytidyltransferase-related domain
G3568_RS17405	COG1051	belongs to the nudix hydrolase family
G3568_RS17410	COG1295	ribonuclease BN
G3568_RS17415	COG1254	Belongs to the acylphosphatase family
G3568_RS17425	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G3568_RS17430	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G3568_RS17440	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
G3568_RS17445	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
G3568_RS17450	COG0632	four-way junction helicase activity
G3568_RS17455	COG2255	four-way junction helicase activity
G3568_RS17460	COG0824	Thioesterase
G3568_RS17480	COG0823	Involved in the tonB-independent uptake of proteins
G3568_RS17485	COG2885	chlorophyll binding
G3568_RS17495	COG1028	Short-chain dehydrogenase reductase Sdr
G3568_RS17510	COG1210	Utp--glucose-1-phosphate uridylyltransferase
G3568_RS17520	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
G3568_RS17540	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G3568_RS17545	COG0429	hydrolase of the alpha beta-hydrolase fold
G3568_RS17550	COG0006	proline dipeptidase activity
G3568_RS17555	COG0288	reversible hydration of carbon dioxide
G3568_RS17565	COG0456	acetyltransferase
G3568_RS17570	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
G3568_RS17575	COG1917	Cupin 2, conserved barrel domain protein
G3568_RS17580	COG0189	ligase activity
G3568_RS17580	COG4067	protein conserved in archaea
G3568_RS17595	COG0735	belongs to the Fur family
G3568_RS17600	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
G3568_RS17605	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
G3568_RS17625	COG2166	iron-sulfur cluster assembly
G3568_RS17640	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
G3568_RS17640	COG0316	Belongs to the HesB IscA family
G3568_RS17650	COG0534	Mate efflux family protein
G3568_RS17665	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G3568_RS17675	COG2840	Smr protein MutS2
G3568_RS17685	COG1393	Belongs to the ArsC family
G3568_RS17700	COG0259	pyridoxamine-phosphate oxidase activity
G3568_RS17720	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
G3568_RS17750	COG3383	formate dehydrogenase (NAD+) activity
G3568_RS17755	COG0437	4 iron, 4 sulfur cluster binding
G3568_RS17770	COG0521	Mo-molybdopterin cofactor biosynthetic process
G3568_RS17775	COG0303	'Molybdopterin
G3568_RS17800	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
G3568_RS17810	COG1643	Atp-dependent helicase
G3568_RS17820	COG1309	transcriptional regulator
G3568_RS17830	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G3568_RS17840	COG0402	S-adenosylhomocysteine deaminase activity
G3568_RS17860	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
G3568_RS17865	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
G3568_RS17870	COG4988	ABC transporter
G3568_RS17875	COG1294	oxidase, subunit
G3568_RS17880	COG1271	oxidase subunit
G3568_RS17890	COG3639	organic phosphonate transmembrane transporter activity
G3568_RS17895	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
G3568_RS17910	COG2995	paraquat-inducible protein a
G3568_RS17915	COG3008	intermembrane lipid transfer
G3568_RS17915	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G3568_RS17930	COG0513	Belongs to the DEAD box helicase family
G3568_RS17965	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
G3568_RS17975	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
G3568_RS17980	COG0745	RESPONSE REGULATOR receiver
G3568_RS17985	COG0840	transmembrane signaling receptor activity
G3568_RS17995	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
G3568_RS18000	COG0840	transmembrane signaling receptor activity
G3568_RS18005	COG0840	transmembrane signaling receptor activity
G3568_RS18010	COG0835	chemotaxis
G3568_RS18015	COG0643	Histidine kinase
G3568_RS18015	COG2198	Histidine kinase
G3568_RS18020	COG1360	Flagellar Motor Protein
G3568_RS18070	COG1177	transmembrane transport
G3568_RS18075	COG1176	ABC-type spermidine putrescine transport system, permease component I
G3568_RS18095	COG2807	transmembrane transport
G3568_RS18100	COG0418	dihydroorotase activity
G3568_RS18130	COG2188	Transcriptional regulator
G3568_RS18150	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
G3568_RS18155	COG0066	3-isopropylmalate dehydratase activity
G3568_RS18170	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G3568_RS18185	COG1473	amidohydrolase
G3568_RS18195	COG1012	belongs to the aldehyde dehydrogenase family
G3568_RS18215	COG2188	Transcriptional regulator
G3568_RS18225	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G3568_RS18235	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G3568_RS18250	COG3706	GGDEF domain
G3568_RS18270	COG1304	FMN binding
G3568_RS18310	COG0129	dihydroxy-acid dehydratase activity
G3568_RS18355	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
G3568_RS18370	COG0438	transferase activity, transferring glycosyl groups
G3568_RS18380	COG2244	polysaccharide biosynthetic process
G3568_RS18390	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
G3568_RS18400	COG0438	transferase activity, transferring glycosyl groups
G3568_RS18420	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
G3568_RS18425	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G3568_RS18450	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
G3568_RS18455	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
G3568_RS18460	COG2895	sulfate adenylyltransferase (ATP) activity
G3568_RS18470	COG0175	sulfate reduction
G3568_RS18490	COG1218	3'(2'),5'-bisphosphate nucleotidase
G3568_RS18495	COG3273	potassium ion transport
G3568_RS18495	COG0471	metal ion transport
G3568_RS18535	COG1484	DNA-dependent DNA replication
G3568_RS18540	COG4584	PFAM Integrase catalytic
G3568_RS18600	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G3568_RS18625	COG3547	Transposase (IS116 IS110 IS902 family)
G3568_RS18645	COG3604	Transcriptional regulator
G3568_RS18665	COG1012	belongs to the aldehyde dehydrogenase family
G3568_RS18680	COG1028	Short-chain dehydrogenase reductase Sdr
G3568_RS18690	COG2721	sulfolactate sulfo-lyase activity
G3568_RS18700	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
G3568_RS18705	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G3568_RS18715	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G3568_RS18720	COG3395	kinase activity
G3568_RS18725	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
G3568_RS18730	COG1028	Short-chain dehydrogenase reductase Sdr
G3568_RS18755	COG1012	belongs to the aldehyde dehydrogenase family
G3568_RS18770	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G3568_RS18775	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G3568_RS18780	COG3622	Belongs to the hyi family
G3568_RS18785	COG0235	Class ii aldolase
G3568_RS18790	COG3395	kinase activity
G3568_RS18795	COG2084	Dehydrogenase
G3568_RS18800	COG1609	Transcriptional regulator
G3568_RS18810	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
G3568_RS18815	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
G3568_RS18835	COG2974	May be involved in recombination
G3568_RS18855	COG5001	Diguanylate cyclase
G3568_RS18880	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G3568_RS18885	COG2274	protein secretion by the type I secretion system
G3568_RS18890	COG2885	chlorophyll binding
G3568_RS18940	COG0237	dephospho-CoA kinase activity
G3568_RS18945	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
G3568_RS18955	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G3568_RS18970	COG2871	sodium ion transport
G3568_RS18975	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
G3568_RS18980	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
G3568_RS18985	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
G3568_RS18990	COG1805	sodium ion transport
G3568_RS19005	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
G3568_RS19010	COG1376	ErfK ybiS ycfS ynhG family protein
G3568_RS19025	COG0488	(ABC) transporter
G3568_RS19075	COG1803	Methylglyoxal synthase
G3568_RS19085	COG5016	pyruvate
G3568_RS19085	COG0511	ligase activity, forming carbon-carbon bonds
G3568_RS19090	COG0439	Biotin carboxylase
G3568_RS19100	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
G3568_RS19105	COG0321	lipoyl(octanoyl) transferase activity
G3568_RS19110	COG2921	Belongs to the UPF0250 family
G3568_RS19115	COG1686	Belongs to the peptidase S11 family
G3568_RS19125	COG2951	lytic endotransglycosylase activity
G3568_RS19130	COG0772	Belongs to the SEDS family
G3568_RS19135	COG0768	penicillin binding
G3568_RS19140	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
G3568_RS19150	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
G3568_RS19155	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
G3568_RS19170	COG0586	Pfam SNARE associated Golgi protein
G3568_RS19175	COG1280	lysine exporter protein (LysE YggA)
G3568_RS19190	COG0205	6-phosphofructokinase activity
G3568_RS19200	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
G3568_RS19215	COG0511	ligase activity, forming carbon-carbon bonds
G3568_RS19225	COG2264	protein methyltransferase activity
G3568_RS19240	COG0138	bifunctional purine biosynthesis protein purh
G3568_RS19255	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
G3568_RS19260	COG0302	gtp cyclohydrolase
G3568_RS19280	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
G3568_RS19285	COG0156	8-amino-7-oxononanoate synthase activity
G3568_RS19300	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
G3568_RS19310	COG4974	Belongs to the 'phage' integrase family
G3568_RS19370	COG0840	transmembrane signaling receptor activity
G3568_RS19375	COG5001	Diguanylate cyclase
G3568_RS19375	COG3300	MHYT domain
G3568_RS19455	COG0582	viral genome integration into host DNA
G3568_RS19475	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
G3568_RS19480	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
G3568_RS19485	COG3706	GGDEF domain
G3568_RS19510	COG0285	dihydrofolate synthase activity
G3568_RS19515	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
G3568_RS19520	COG0159	tryptophan synthase activity
G3568_RS19555	COG0135	phosphoribosylanthranilate isomerase activity
G3568_RS19575	COG0473	3-isopropylmalate dehydrogenase activity
G3568_RS19580	COG0066	3-isopropylmalate dehydratase activity
G3568_RS19585	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
G3568_RS19635	COG0367	asparagine synthase
G3568_RS19680	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
G3568_RS19685	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G3568_RS19700	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
G3568_RS19705	COG0438	transferase activity, transferring glycosyl groups
G3568_RS19715	COG0438	transferase activity, transferring glycosyl groups
G3568_RS19735	COG0463	Glycosyl transferase, family 2
G3568_RS19740	COG2895	sulfate adenylyltransferase (ATP) activity
G3568_RS19745	COG0175	sulfate reduction
G3568_RS19755	COG2244	polysaccharide biosynthetic process
G3568_RS19775	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
G3568_RS19805	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G3568_RS19820	COG0495	leucyl-tRNA aminoacylation
G3568_RS19835	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G3568_RS19840	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
G3568_RS19865	COG1845	cytochrome c oxidase, subunit III
G3568_RS19875	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
G3568_RS19900	COG1228	amidohydrolase
G3568_RS19905	COG0010	Belongs to the arginase family
G3568_RS19915	COG2986	histidine ammonia-lyase
G3568_RS19920	COG2056	Na+-H+ antiporter family
G3568_RS19960	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G3568_RS19975	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G3568_RS19980	COG1881	PFAM PEBP family protein
G3568_RS19995	COG0432	Pfam Uncharacterised protein family UPF0047
G3568_RS20000	COG2824	Alkylphosphonate utilization operon protein PhnA
G3568_RS20030	COG3118	belongs to the thioredoxin family
G3568_RS20045	COG0006	proline dipeptidase activity
G3568_RS20055	COG0583	DNA-binding transcription factor activity
G3568_RS20060	COG3189	MarR family transcriptional regulator
G3568_RS20065	COG1115	amino acid carrier protein
G3568_RS20075	COG0183	Belongs to the thiolase family
G3568_RS20100	COG0589	response to stress
G3568_RS20120	COG3101	peptidyl-lysine hydroxylation
G3568_RS20140	COG0425	Belongs to the sulfur carrier protein TusA family
G3568_RS20150	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
G3568_RS20155	COG2433	Pfam Transposase IS66
G3568_RS20220	COG1309	transcriptional regulator
G3568_RS20240	COG0517	IMP dehydrogenase activity
G3568_RS20240	COG4175	Glycine betaine
G3568_RS20255	COG0471	metal ion transport
G3568_RS20255	COG3273	potassium ion transport
G3568_RS20260	COG1024	Enoyl-CoA hydratase
G3568_RS20270	COG1024	Enoyl-CoA hydratase
G3568_RS20275	COG1737	Transcriptional regulator
G3568_RS20300	COG1492	cobalamin metabolic process
G3568_RS20315	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
G3568_RS20320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G3568_RS20325	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G3568_RS20330	COG4206	TonB-dependent receptor
G3568_RS20340	COG0588	phosphoglycerate mutase activity
G3568_RS20345	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
G3568_RS20355	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G3568_RS20360	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
G3568_RS20365	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
G3568_RS20395	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
G3568_RS20420	COG0395	ABC-type sugar transport system, permease component
G3568_RS20425	COG3842	ATPase activity
G3568_RS20430	COG0438	transferase activity, transferring glycosyl groups
G3568_RS20440	COG0483	inositol monophosphate 1-phosphatase activity
G3568_RS20445	COG0737	Belongs to the 5'-nucleotidase family
G3568_RS20455	COG3842	ATPase activity
G3568_RS20490	COG1028	Short-chain dehydrogenase reductase Sdr
G3568_RS20520	COG1414	Transcriptional regulator
G3568_RS20550	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G3568_RS20560	COG1335	isochorismatase
G3568_RS20570	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
G3568_RS20590	COG0745	RESPONSE REGULATOR receiver
G3568_RS20595	COG2205	protein histidine kinase activity
G3568_RS20605	COG0154	amidase activity
G3568_RS20610	COG0730	response to heat
G3568_RS20620	COG1666	GTP binding
G3568_RS20630	COG0189	ligase activity
G3568_RS20655	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
G3568_RS20680	COG0395	ABC-type sugar transport system, permease component
G3568_RS20695	COG3842	ATPase activity
G3568_RS20710	COG0617	tRNA 3'-terminal CCA addition
G3568_RS20710	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
G3568_RS20710	COG0517	IMP dehydrogenase activity
G3568_RS20720	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
G3568_RS20735	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
G3568_RS20735	COG0506	proline dehydrogenase activity
G3568_RS20735	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
G3568_RS20740	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G3568_RS20750	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G3568_RS20770	COG3098	single-species biofilm formation
G3568_RS20780	COG0189	ligase activity
G3568_RS20780	COG4067	protein conserved in archaea
G3568_RS20785	COG0189	ligase activity
G3568_RS20795	COG2949	membrane
G3568_RS20805	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G3568_RS20810	COG0719	Fe-S assembly protein
G3568_RS20815	COG0396	ATPase activity
G3568_RS20820	COG0719	Fe-S assembly protein
G3568_RS20825	COG1959	2 iron, 2 sulfur cluster binding
G3568_RS20865	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
G3568_RS20870	COG0330	HflC and HflK could
G3568_RS20875	COG0330	HflC and HflK could
G3568_RS20880	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
G3568_RS20885	COG1923	regulation of RNA biosynthetic process
G3568_RS20890	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
G3568_RS20895	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
G3568_RS20900	COG0860	N-Acetylmuramoyl-L-alanine amidase
G3568_RS20905	COG0802	atpase or kinase
G3568_RS20910	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
G3568_RS20910	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
G3568_RS20920	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
G3568_RS20925	COG1162	GTPase activity
G3568_RS20935	COG0688	phosphatidylethanolamine metabolic process
G3568_RS20945	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
G3568_RS20950	COG1509	lysine 2,3-aminomutase activity
G3568_RS20960	COG2084	Dehydrogenase
G3568_RS20965	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
G3568_RS20970	COG3395	kinase activity
G3568_RS20975	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G3568_RS21010	COG2199	diguanylate cyclase activity
G3568_RS21010	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
G3568_RS21020	COG0560	Phosphoserine phosphatase
G3568_RS21020	COG3830	Belongs to the UPF0237 family
G3568_RS21040	COG0166	Belongs to the GPI family
G3568_RS21045	COG4106	trans-aconitate 2-methyltransferase activity
G3568_RS21055	COG0500	methyltransferase
G3568_RS21060	COG2738	Putative neutral zinc metallopeptidase
G3568_RS21080	COG4558	Periplasmic binding protein
G3568_RS21085	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G3568_RS21100	COG2895	sulfate adenylyltransferase (ATP) activity
G3568_RS21105	COG0175	sulfate reduction
G3568_RS21110	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
G3568_RS21115	COG3151	Protein conserved in bacteria
G3568_RS21120	COG0494	nUDIX hydrolase
G3568_RS21135	COG2813	Specifically methylates the guanine in position
G3568_RS21140	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G3568_RS21155	COG5001	Diguanylate cyclase
G3568_RS21155	COG3706	GGDEF domain
G3568_RS21155	COG4251	negative regulation of phosphorylation
G3568_RS21155	COG2203	Gaf domain
G3568_RS21165	COG3706	GGDEF domain
G3568_RS21175	COG1177	transmembrane transport
G3568_RS21180	COG1176	ABC-type spermidine putrescine transport system, permease component I
G3568_RS21185	COG3842	ATPase activity
G3568_RS21200	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
G3568_RS21210	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
G3568_RS21215	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
G3568_RS21220	COG3279	Response regulator of the LytR AlgR family
G3568_RS21235	COG0494	nUDIX hydrolase
G3568_RS21245	COG0579	oxidoreductase
G3568_RS21255	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G3568_RS21270	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
G3568_RS21275	COG2918	glutathione biosynthetic process
G3568_RS21280	COG2183	response to ionizing radiation
G3568_RS21290	COG0583	DNA-binding transcription factor activity
G3568_RS21300	COG1053	succinate dehydrogenase
G3568_RS21310	COG1012	belongs to the aldehyde dehydrogenase family
G3568_RS21320	COG2175	clavaminate synthase activity
G3568_RS21325	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G3568_RS21355	COG1028	Short-chain dehydrogenase reductase Sdr
G3568_RS21370	COG2826	transposase and inactivated derivatives, IS30 family
G3568_RS21380	COG0625	glutathione transferase activity
G3568_RS21390	COG0583	DNA-binding transcription factor activity
G3568_RS21405	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G3568_RS21410	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
G3568_RS21415	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
G3568_RS21420	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
G3568_RS21425	COG1011	Hydrolase
G3568_RS21430	COG0494	nUDIX hydrolase
G3568_RS21435	COG0673	inositol 2-dehydrogenase activity
G3568_RS21440	COG0129	dihydroxy-acid dehydratase activity
G3568_RS21460	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
G3568_RS21470	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G3568_RS21475	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
G3568_RS21485	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G3568_RS21485	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G3568_RS21490	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
G3568_RS21495	COG0366	Alpha amylase catalytic
G3568_RS21500	COG2217	Heavy metal translocating P-type atpase
G3568_RS21505	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G3568_RS21515	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G3568_RS21525	COG0642	Histidine kinase
G3568_RS21535	COG2391	methyltransferase activity
G3568_RS21565	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
G3568_RS21570	COG1215	transferase activity, transferring glycosyl groups
G3568_RS21580	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
G3568_RS21585	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
G3568_RS21590	COG4181	ATPase activity
G3568_RS21625	COG1366	Belongs to the anti-sigma-factor antagonist family
G3568_RS21645	COG1560	Kdo2-lipid A biosynthetic process
G3568_RS21650	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G3568_RS21655	COG1538	Outer membrane efflux protein
G3568_RS21675	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
G3568_RS21680	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
G3568_RS21685	COG0585	pseudouridine synthase activity
G3568_RS21690	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
G3568_RS21695	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
G3568_RS21700	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
G3568_RS21720	COG0837	glucose binding
G3568_RS21730	COG4989	oxidoreductase activity
G3568_RS21735	COG0166	Belongs to the GPI family
G3568_RS21740	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G3568_RS21755	COG2203	Gaf domain
G3568_RS21755	COG3706	GGDEF domain
G3568_RS21755	COG4251	negative regulation of phosphorylation
G3568_RS21755	COG5001	Diguanylate cyclase
G3568_RS21870	COG1309	transcriptional regulator
G3568_RS21890	COG3604	Transcriptional regulator
G3568_RS21895	COG1116	anion transmembrane transporter activity
G3568_RS21895	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G3568_RS21900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3568_RS21905	COG1116	anion transmembrane transporter activity
G3568_RS21915	COG3001	Fructosamine kinase
G3568_RS21920	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
G3568_RS21925	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
G3568_RS21930	COG1070	Carbohydrate kinase
G3568_RS21940	COG1072	(Pantothenic acid kinase))
G3568_RS21945	COG1028	Short-chain dehydrogenase reductase Sdr
G3568_RS21955	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G3568_RS21965	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G3568_RS21970	COG3842	ATPase activity
G3568_RS21980	COG1175	transmembrane transport
G3568_RS21990	COG2390	Transcriptional regulator
G3568_RS21995	COG4221	oxidoreductase activity
G3568_RS22000	COG0583	DNA-binding transcription factor activity
G3568_RS22015	COG0765	amino acid transport
G3568_RS22025	COG3665	Urea carboxylase-associated protein
G3568_RS22085	COG1063	alcohol dehydrogenase
G3568_RS22095	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
G3568_RS22105	COG0583	DNA-binding transcription factor activity
G3568_RS22115	COG2207	Transcriptional regulator
G3568_RS22120	COG1064	alcohol dehydrogenase
G3568_RS22135	COG3608	succinylglutamate desuccinylase aspartoacylase
G3568_RS22135	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
G3568_RS22145	COG0235	Class ii aldolase
G3568_RS22150	COG3395	kinase activity
G3568_RS22180	COG0473	3-isopropylmalate dehydrogenase activity
G3568_RS22210	COG1024	Enoyl-CoA hydratase
G3568_RS22245	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
G3568_RS22250	COG2943	transferase activity, transferring hexosyl groups
G3568_RS22280	COG0438	transferase activity, transferring glycosyl groups
G3568_RS22300	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
G3568_RS22320	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G3568_RS22340	COG0318	PFAM AMP-dependent synthetase and ligase
G3568_RS22355	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
G3568_RS22365	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
G3568_RS22375	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
G3568_RS22390	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
G3568_RS22395	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
G3568_RS22405	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
G3568_RS22410	COG0813	purine-nucleoside phosphorylase activity
G3568_RS22450	COG3210	domain, Protein
G3568_RS22450	COG3210	domain, Protein
G3568_RS22450	COG3210	domain, Protein
G3568_RS22455	COG2831	hemolysin activation secretion protein
G3568_RS22480	COG0668	transmembrane transport
G3568_RS22490	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
G3568_RS22495	COG1764	response to oxidative stress
G3568_RS22500	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
G3568_RS22510	COG0656	L-ascorbic acid biosynthetic process
G3568_RS22515	COG1515	deoxyribonuclease V activity