locus-tag	class	description
FDY98_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FDY98_RS00030	COG0751	glycine-tRNA ligase activity
FDY98_RS00035	COG0752	glycyl-tRNA synthetase alpha subunit
FDY98_RS00060	COG0438	transferase activity, transferring glycosyl groups
FDY98_RS00065	COG0463	Glycosyl transferase, family 2
FDY98_RS00070	COG0438	transferase activity, transferring glycosyl groups
FDY98_RS00075	COG1442	glycosyl transferase family 8
FDY98_RS00080	COG3307	-O-antigen
FDY98_RS00095	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FDY98_RS00095	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FDY98_RS00100	COG1519	Transferase
FDY98_RS00110	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FDY98_RS00115	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FDY98_RS00135	COG0006	proline dipeptidase activity
FDY98_RS00140	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FDY98_RS00145	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FDY98_RS00150	COG0793	Belongs to the peptidase S41A family
FDY98_RS00155	COG4942	peptidase
FDY98_RS00165	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FDY98_RS00170	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FDY98_RS00175	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FDY98_RS00185	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FDY98_RS00190	COG2996	Protein conserved in bacteria
FDY98_RS00195	COG0189	ligase activity
FDY98_RS00200	COG1678	Uncharacterized ACR, COG1678
FDY98_RS00205	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FDY98_RS00210	COG0540	Belongs to the ATCase OTCase family
FDY98_RS00240	COG0023	Translation Initiation Factor
FDY98_RS00245	COG0546	phosphoglycolate phosphatase activity
FDY98_RS00290	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FDY98_RS00295	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FDY98_RS00305	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FDY98_RS00325	COG0339	signal peptide processing
FDY98_RS00330	COG0733	neurotransmitter:sodium symporter activity
FDY98_RS00335	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FDY98_RS00360	COG1304	FMN binding
FDY98_RS00415	COG1558	bacterial-type flagellum-dependent cell motility
FDY98_RS00425	COG1749	Flagellar hook protein flgE
FDY98_RS00445	COG1706	bacterial-type flagellum-dependent cell motility
FDY98_RS00450	COG3951	Flagellar rod assembly protein muramidase FlgJ
FDY98_RS00450	COG1705	Flagellar rod assembly protein muramidase FlgJ
FDY98_RS00470	COG1987	bacterial-type flagellum assembly
FDY98_RS00480	COG3190	flagellar
FDY98_RS00505	COG2882	bacterial-type flagellum organization
FDY98_RS00525	COG1766	The M ring may be actively involved in energy transduction
FDY98_RS00530	COG1677	Flagellar hook-basal body complex protein FliE
FDY98_RS00535	COG1334	flagellar protein FlaG
FDY98_RS00560	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FDY98_RS00580	COG1360	Flagellar Motor Protein
FDY98_RS00590	COG0835	chemotaxis
FDY98_RS00600	COG0840	transmembrane signaling receptor activity
FDY98_RS00610	COG2201	protein-glutamate methylesterase activity
FDY98_RS00615	COG0840	transmembrane signaling receptor activity
FDY98_RS00620	COG0745	RESPONSE REGULATOR receiver
FDY98_RS00635	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FDY98_RS00690	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FDY98_RS00705	COG0629	single-stranded DNA binding
FDY98_RS00775	COG0300	oxidoreductase activity
FDY98_RS00795	COG1090	epimerase
FDY98_RS00800	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FDY98_RS00805	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FDY98_RS00855	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FDY98_RS00855	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FDY98_RS00860	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FDY98_RS00895	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FDY98_RS00900	COG0081	regulation of translation
FDY98_RS00905	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FDY98_RS00910	COG0222	ribosome binding
FDY98_RS00915	COG0085	RNA polymerase activity
FDY98_RS00920	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FDY98_RS00925	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FDY98_RS00930	COG0049	tRNA binding
FDY98_RS00940	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FDY98_RS00945	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FDY98_RS00950	COG0051	transcription antitermination factor activity, RNA binding
FDY98_RS00955	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FDY98_RS00960	COG0088	Forms part of the polypeptide exit tunnel
FDY98_RS00965	COG0089	rRNA binding
FDY98_RS00970	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FDY98_RS00980	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FDY98_RS00995	COG0255	Belongs to the universal ribosomal protein uL29 family
FDY98_RS01000	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FDY98_RS01010	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FDY98_RS01015	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FDY98_RS01020	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FDY98_RS01025	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FDY98_RS01030	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FDY98_RS01035	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FDY98_RS01040	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FDY98_RS01045	COG1841	ribosomal large subunit assembly
FDY98_RS01050	COG0200	Binds to the 23S rRNA
FDY98_RS01060	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FDY98_RS01065	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FDY98_RS01070	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FDY98_RS01075	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FDY98_RS01085	COG0203	ribosomal protein L17
FDY98_RS01090	COG1686	Belongs to the peptidase S11 family
FDY98_RS01120	COG0352	thiamine-phosphate diphosphorylase activity
FDY98_RS01170	COG1121	(ABC) transporter
FDY98_RS01200	COG1857	crispr-associated protein
FDY98_RS01215	COG1518	maintenance of DNA repeat elements
FDY98_RS01220	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FDY98_RS01230	COG0501	Belongs to the peptidase M48B family
FDY98_RS01270	COG2204	response regulator
FDY98_RS01285	COG5510	response to toxic substance
FDY98_RS01290	COG0671	phosphoesterase, PA-phosphatase related
FDY98_RS01305	COG0737	Belongs to the 5'-nucleotidase family
FDY98_RS01310	COG5507	3-demethylubiquinone-9 3-methyltransferase
FDY98_RS01315	COG3795	YCII-related domain
FDY98_RS01325	COG0583	DNA-binding transcription factor activity
FDY98_RS01330	COG0667	Aldo Keto reductase
FDY98_RS01350	COG1175	transmembrane transport
FDY98_RS01380	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FDY98_RS01465	COG2814	Major facilitator Superfamily
FDY98_RS01470	COG4948	Mandelate Racemase Muconate Lactonizing
FDY98_RS01475	COG1454	alcohol dehydrogenase
FDY98_RS01480	COG1012	belongs to the aldehyde dehydrogenase family
FDY98_RS01485	COG0583	DNA-binding transcription factor activity
FDY98_RS01490	COG0583	DNA-binding transcription factor activity
FDY98_RS01500	COG0006	proline dipeptidase activity
FDY98_RS01515	COG0142	geranyltranstransferase activity
FDY98_RS01520	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FDY98_RS01525	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FDY98_RS01530	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FDY98_RS01535	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FDY98_RS01585	COG3639	organic phosphonate transmembrane transporter activity
FDY98_RS01645	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FDY98_RS01670	COG1278	Cold shock
FDY98_RS01675	COG3443	Belongs to the bacterial solute-binding protein 9 family
FDY98_RS01690	COG0531	amino acid
FDY98_RS01710	COG1028	Short-chain dehydrogenase reductase Sdr
FDY98_RS01715	COG1733	regulation of RNA biosynthetic process
FDY98_RS01750	COG4191	Histidine kinase
FDY98_RS01790	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FDY98_RS01795	COG2867	negative regulation of translational initiation
FDY98_RS01800	COG2914	Belongs to the UPF0125 (RnfH) family
FDY98_RS01805	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FDY98_RS01815	COG0497	DNA recombination
FDY98_RS01820	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FDY98_RS01830	COG0484	heat shock protein binding
FDY98_RS01840	COG1120	ATPase activity
FDY98_RS01845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FDY98_RS01895	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FDY98_RS01905	COG0149	triose-phosphate isomerase activity
FDY98_RS01910	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FDY98_RS01925	COG0779	Required for maturation of 30S ribosomal subunits
FDY98_RS01930	COG0195	Participates in both transcription termination and antitermination
FDY98_RS01935	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FDY98_RS01940	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FDY98_RS01945	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FDY98_RS01950	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FDY98_RS01955	COG1185	polyribonucleotide nucleotidyltransferase activity
FDY98_RS01965	COG0583	DNA-binding transcription factor activity
FDY98_RS01970	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FDY98_RS01985	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FDY98_RS02000	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FDY98_RS02005	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FDY98_RS02010	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FDY98_RS02025	COG0617	tRNA 3'-terminal CCA addition
FDY98_RS02030	COG2204	response regulator
FDY98_RS02045	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FDY98_RS02055	COG1489	DNA binding
FDY98_RS02065	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FDY98_RS02065	COG2813	Specifically methylates the guanine in position
FDY98_RS02070	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FDY98_RS02095	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FDY98_RS02225	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FDY98_RS02230	COG2925	Exonuclease
FDY98_RS02260	COG4137	Cytochrome C assembly protein
FDY98_RS02265	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FDY98_RS02270	COG0228	four-way junction DNA binding
FDY98_RS02275	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FDY98_RS02280	COG0336	Belongs to the RNA methyltransferase TrmD family
FDY98_RS02285	COG0335	large ribosomal subunit rRNA binding
FDY98_RS02310	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FDY98_RS02325	COG0789	Transcriptional regulator
FDY98_RS02395	COG0742	ribosomal rna small subunit methyltransferase
FDY98_RS02410	COG2177	Part of the ABC transporter FtsEX involved in
FDY98_RS02420	COG1309	transcriptional regulator
FDY98_RS02445	COG2003	Belongs to the UPF0758 family
FDY98_RS02450	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FDY98_RS02455	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FDY98_RS02460	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FDY98_RS02475	COG0686	Belongs to the AlaDH PNT family
FDY98_RS02495	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FDY98_RS02530	COG0052	Belongs to the universal ribosomal protein uS2 family
FDY98_RS02535	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FDY98_RS02545	COG0233	cytoplasmic translational termination
FDY98_RS02550	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FDY98_RS02560	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FDY98_RS02580	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FDY98_RS02585	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FDY98_RS02595	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FDY98_RS02600	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FDY98_RS02610	COG0825	malonyl-CoA metabolic process
FDY98_RS02615	COG0037	tRNA processing
FDY98_RS02630	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FDY98_RS02660	COG0346	lactoylglutathione lyase activity
FDY98_RS02675	COG2199	diguanylate cyclase activity
FDY98_RS02675	COG2203	Gaf domain
FDY98_RS02685	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FDY98_RS02700	COG4136	ATPase activity
FDY98_RS02705	COG4135	transport system, permease component
FDY98_RS02710	COG4134	Bacterial extracellular solute-binding protein
FDY98_RS02770	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FDY98_RS02775	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FDY98_RS02780	COG0795	lipopolysaccharide-transporting ATPase activity
FDY98_RS02785	COG0795	lipopolysaccharide-transporting ATPase activity
FDY98_RS02810	COG1966	Carbon starvation protein
FDY98_RS02835	COG0444	Belongs to the ABC transporter superfamily
FDY98_RS02840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FDY98_RS02865	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FDY98_RS02885	COG1473	amidohydrolase
FDY98_RS02930	COG2943	transferase activity, transferring hexosyl groups
FDY98_RS02945	COG4302	ethanolamine ammonia-lyase activity
FDY98_RS02950	COG0531	amino acid
FDY98_RS02965	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FDY98_RS02975	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FDY98_RS02980	COG1073	alpha beta
FDY98_RS02980	COG2226	methyltransferase
FDY98_RS03000	COG3148	PFAM DTW domain containing protein
FDY98_RS03010	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FDY98_RS03020	COG3360	Dodecin
FDY98_RS03035	COG0242	peptide deformylase activity
FDY98_RS03045	COG0758	DNA mediated transformation
FDY98_RS03050	COG0009	L-threonylcarbamoyladenylate synthase
FDY98_RS03080	COG1160	GTP binding
FDY98_RS03090	COG2976	Protein conserved in bacteria
FDY98_RS03095	COG0124	histidyl-tRNA synthetase
FDY98_RS03115	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FDY98_RS03120	COG0105	UTP biosynthetic process
FDY98_RS03125	COG0316	Belongs to the HesB IscA family
FDY98_RS03130	COG1104	cysteine desulfurase activity
FDY98_RS03165	COG1862	Preprotein translocase
FDY98_RS03170	COG0343	queuine tRNA-ribosyltransferase activity
FDY98_RS03195	COG0251	oxidation-reduction process
FDY98_RS03200	COG2423	ornithine cyclodeaminase activity
FDY98_RS03250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FDY98_RS03255	COG0601	transmembrane transport
FDY98_RS03260	COG0747	negative chemotaxis
FDY98_RS03285	COG0006	proline dipeptidase activity
FDY98_RS03335	COG1234	tRNA 3'-trailer cleavage
FDY98_RS03345	COG3093	addiction module antidote protein HigA
FDY98_RS03365	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FDY98_RS03370	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FDY98_RS03375	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FDY98_RS03385	COG1028	Short-chain dehydrogenase reductase Sdr
FDY98_RS03435	COG2200	EAL domain
FDY98_RS03435	COG2199	diguanylate cyclase activity
FDY98_RS03440	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FDY98_RS03445	COG1960	acyl-CoA dehydrogenase activity
FDY98_RS03450	COG1802	Transcriptional regulator
FDY98_RS03515	COG0493	'glutamate synthase
FDY98_RS03520	COG0504	CTP synthase activity
FDY98_RS03525	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FDY98_RS03545	COG1546	Belongs to the CinA family
FDY98_RS03550	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FDY98_RS03565	COG0527	aspartate kinase activity
FDY98_RS03570	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FDY98_RS03600	COG5016	pyruvate
FDY98_RS03600	COG0511	ligase activity, forming carbon-carbon bonds
FDY98_RS03605	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
FDY98_RS03610	COG1739	Uncharacterized protein family UPF0029
FDY98_RS03620	COG4133	protoheme IX ABC transporter activity
FDY98_RS03640	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FDY98_RS03655	COG3088	subunit of a heme lyase
FDY98_RS03670	COG3115	cell septum assembly
FDY98_RS03685	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FDY98_RS03685	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FDY98_RS03690	COG2350	Protein conserved in bacteria
FDY98_RS03695	COG0613	PHP domain protein
FDY98_RS03710	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FDY98_RS03720	COG1392	Phosphate transport regulator
FDY98_RS03725	COG0306	phosphate transporter
FDY98_RS03750	COG1028	Short-chain dehydrogenase reductase Sdr
FDY98_RS03760	COG1570	exodeoxyribonuclease VII activity
FDY98_RS03775	COG3842	ATPase activity
FDY98_RS03790	COG1349	DNA-binding transcription factor activity
FDY98_RS03835	COG2197	response regulator
FDY98_RS03885	COG2207	Transcriptional regulator
FDY98_RS03905	COG1309	transcriptional regulator
FDY98_RS03910	COG1028	Short-chain dehydrogenase reductase Sdr
FDY98_RS03930	COG0583	DNA-binding transcription factor activity
FDY98_RS03990	COG0456	acetyltransferase
FDY98_RS03990	COG1846	Transcriptional regulator
FDY98_RS04025	COG1733	regulation of RNA biosynthetic process
FDY98_RS04035	COG0456	acetyltransferase
FDY98_RS04035	COG1846	Transcriptional regulator
FDY98_RS04045	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FDY98_RS04055	COG2205	protein histidine kinase activity
FDY98_RS04060	COG0745	RESPONSE REGULATOR receiver
FDY98_RS04080	COG0583	DNA-binding transcription factor activity
FDY98_RS04085	COG2195	Cleaves the N-terminal amino acid of tripeptides
FDY98_RS04090	COG1288	antiporter activity
FDY98_RS04125	COG0583	DNA-binding transcription factor activity
FDY98_RS04130	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FDY98_RS04140	COG2814	Major facilitator Superfamily
FDY98_RS04145	COG4774	siderophore transport
FDY98_RS04195	COG2807	transmembrane transport
FDY98_RS04240	COG0642	Histidine kinase
FDY98_RS04285	COG1028	Short-chain dehydrogenase reductase Sdr
FDY98_RS04290	COG0667	Aldo Keto reductase
FDY98_RS04295	COG0667	Aldo Keto reductase
FDY98_RS04305	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FDY98_RS04335	COG2259	Doxx family
FDY98_RS04340	COG2207	Transcriptional regulator
FDY98_RS04350	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FDY98_RS04355	COG2080	2 iron, 2 sulfur cluster binding
FDY98_RS04395	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FDY98_RS04400	COG2207	Transcriptional regulator
FDY98_RS04410	COG4221	oxidoreductase activity
FDY98_RS04415	COG0583	DNA-binding transcription factor activity
FDY98_RS04450	COG0110	maltose O-acetyltransferase activity
FDY98_RS04455	COG0251	oxidation-reduction process
FDY98_RS04470	COG1566	PFAM secretion protein HlyD family protein
FDY98_RS04500	COG0583	DNA-binding transcription factor activity
FDY98_RS04525	COG2249	NAD(P)H dehydrogenase (quinone) activity
FDY98_RS04530	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FDY98_RS04540	COG0069	glutamate synthase activity
FDY98_RS04565	COG5499	transcription regulator containing HTH domain
FDY98_RS04570	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FDY98_RS04645	COG2207	Transcriptional regulator
FDY98_RS04650	COG1301	dicarboxylic acid transport
FDY98_RS04670	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FDY98_RS04765	COG1120	ATPase activity
FDY98_RS04770	COG0483	inositol monophosphate 1-phosphatase activity
FDY98_RS04845	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FDY98_RS04875	COG4607	ABC-type enterochelin transport system periplasmic component
FDY98_RS04880	COG4774	siderophore transport
FDY98_RS04885	COG0657	acetylesterase activity
FDY98_RS04915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FDY98_RS04970	COG4774	siderophore transport
FDY98_RS04980	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FDY98_RS05010	COG3250	beta-galactosidase activity
FDY98_RS05030	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FDY98_RS05035	COG0723	plastoquinol--plastocyanin reductase activity
FDY98_RS05035	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FDY98_RS05040	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FDY98_RS05045	COG0501	Belongs to the peptidase M48B family
FDY98_RS05055	COG4948	Mandelate Racemase Muconate Lactonizing
FDY98_RS05080	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FDY98_RS05100	COG2721	sulfolactate sulfo-lyase activity
FDY98_RS05125	COG0028	Belongs to the TPP enzyme family
FDY98_RS05135	COG2186	Transcriptional regulator
FDY98_RS05230	COG2146	nitrite reductase [NAD(P)H] activity
FDY98_RS05230	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FDY98_RS05235	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FDY98_RS05240	COG0243	molybdopterin cofactor binding
FDY98_RS05260	COG0656	L-ascorbic acid biosynthetic process
FDY98_RS05320	COG3181	Tripartite tricarboxylate transporter family receptor
FDY98_RS05325	COG2059	Chromate
FDY98_RS05330	COG2059	Chromate
FDY98_RS05360	COG4221	oxidoreductase activity
FDY98_RS05400	COG0583	DNA-binding transcription factor activity
FDY98_RS05405	COG0435	Glutathione S-transferase
FDY98_RS05430	COG1515	deoxyribonuclease V activity
FDY98_RS05435	COG0519	Catalyzes the synthesis of GMP from XMP
FDY98_RS05435	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FDY98_RS05490	COG0673	inositol 2-dehydrogenase activity
FDY98_RS05515	COG0813	purine-nucleoside phosphorylase activity
FDY98_RS05520	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FDY98_RS05525	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FDY98_RS05530	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FDY98_RS05535	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FDY98_RS05545	COG1349	DNA-binding transcription factor activity
FDY98_RS05550	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FDY98_RS05555	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FDY98_RS05560	COG1845	cytochrome c oxidase, subunit III
FDY98_RS05565	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FDY98_RS05570	COG0109	protoheme IX farnesyltransferase activity
FDY98_RS05620	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FDY98_RS05625	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FDY98_RS05655	COG1309	transcriptional regulator
FDY98_RS05685	COG4115	mRNA cleavage
FDY98_RS05690	COG2161	toxin-antitoxin pair type II binding
FDY98_RS05700	COG0583	DNA-binding transcription factor activity
FDY98_RS05705	COG0604	alcohol dehydrogenase
FDY98_RS05720	COG1609	Transcriptional regulator
FDY98_RS05725	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FDY98_RS05730	COG1914	H( )-stimulated, divalent metal cation uptake system
FDY98_RS05755	COG2207	Transcriptional regulator
FDY98_RS05755	COG0662	Cupin 2, conserved barrel domain protein
FDY98_RS05765	COG0454	-acetyltransferase
FDY98_RS05785	COG4977	sequence-specific DNA binding
FDY98_RS05790	COG0697	spore germination
FDY98_RS05805	COG0656	L-ascorbic acid biosynthetic process
FDY98_RS05810	COG2942	2-epimerase
FDY98_RS05825	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FDY98_RS05880	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FDY98_RS05885	COG0583	DNA-binding transcription factor activity
FDY98_RS05890	COG2814	Major facilitator Superfamily
FDY98_RS05895	COG0667	Aldo Keto reductase
FDY98_RS05915	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FDY98_RS05925	COG0583	DNA-binding transcription factor activity
FDY98_RS05940	COG3070	regulator of competence-specific genes
FDY98_RS05955	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FDY98_RS05960	COG0583	DNA-binding transcription factor activity
FDY98_RS05970	COG0789	Transcriptional regulator
FDY98_RS05990	COG0477	Major facilitator Superfamily
FDY98_RS05995	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FDY98_RS06005	COG1595	DNA-templated transcription, initiation
FDY98_RS06010	COG1971	Probably functions as a manganese efflux pump
FDY98_RS06015	COG4977	sequence-specific DNA binding
FDY98_RS06035	COG0583	DNA-binding transcription factor activity
FDY98_RS06040	COG3791	Glutathione-dependent formaldehyde-activating
FDY98_RS06060	COG0438	transferase activity, transferring glycosyl groups
FDY98_RS06130	COG1960	acyl-CoA dehydrogenase activity
FDY98_RS06135	COG0318	PFAM AMP-dependent synthetase and ligase
FDY98_RS06140	COG1250	3-hydroxyacyl-CoA dehydrogenase
FDY98_RS06145	COG1024	Enoyl-CoA hydratase
FDY98_RS06155	COG0625	glutathione transferase activity
FDY98_RS06180	COG0625	glutathione transferase activity
FDY98_RS06190	COG1764	response to oxidative stress
FDY98_RS06195	COG1846	Transcriptional regulator
FDY98_RS06215	COG3265	gluconokinase activity
FDY98_RS06220	COG1609	Transcriptional regulator
FDY98_RS06235	COG1764	response to oxidative stress
FDY98_RS06280	COG1175	transmembrane transport
FDY98_RS06305	COG1072	(Pantothenic acid kinase))
FDY98_RS06315	COG1070	Carbohydrate kinase
FDY98_RS06330	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
FDY98_RS06350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDY98_RS06385	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FDY98_RS06400	COG3561	AntA/AntB antirepressor
FDY98_RS06485	COG1598	PFAM Uncharacterised protein family UPF0150
FDY98_RS06640	COG3772	lysozyme
FDY98_RS06680	COG4695	Portal protein
FDY98_RS06710	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FDY98_RS06735	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FDY98_RS06740	COG1053	succinate dehydrogenase
FDY98_RS06810	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FDY98_RS06850	COG1175	transmembrane transport
FDY98_RS06855	COG0395	ABC-type sugar transport system, permease component
FDY98_RS06860	COG3842	ATPase activity
FDY98_RS06870	COG3768	UPF0283 membrane protein
FDY98_RS06885	COG0676	glucose-6-phosphate 1-epimerase activity
FDY98_RS06900	COG0791	NLP P60 protein
FDY98_RS06910	COG1124	(ABC) transporter
FDY98_RS06915	COG0577	efflux transmembrane transporter activity
FDY98_RS06915	COG1136	(ABC) transporter
FDY98_RS06920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FDY98_RS06925	COG0601	transmembrane transport
FDY98_RS06965	COG2850	peptidyl-arginine hydroxylation
FDY98_RS06980	COG0482	sulfurtransferase activity
FDY98_RS07005	COG0542	response to heat
FDY98_RS07010	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FDY98_RS07015	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FDY98_RS07020	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FDY98_RS07035	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FDY98_RS07045	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FDY98_RS07065	COG3130	regulation of translation
FDY98_RS07070	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FDY98_RS07070	COG0116	Belongs to the methyltransferase superfamily
FDY98_RS07085	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FDY98_RS07090	COG0501	Belongs to the peptidase M48B family
FDY98_RS07100	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FDY98_RS07105	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FDY98_RS07115	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FDY98_RS07125	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FDY98_RS07160	COG1012	belongs to the aldehyde dehydrogenase family
FDY98_RS07170	COG0842	Transport permease protein
FDY98_RS07175	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FDY98_RS07175	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FDY98_RS07225	COG2003	Belongs to the UPF0758 family
FDY98_RS07270	COG3311	Transcriptional regulator
FDY98_RS07285	COG2194	sulfuric ester hydrolase activity
FDY98_RS07295	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FDY98_RS07340	COG2391	methyltransferase activity
FDY98_RS07380	COG0583	DNA-binding transcription factor activity
FDY98_RS07385	COG1960	acyl-CoA dehydrogenase activity
FDY98_RS07425	COG0583	DNA-binding transcription factor activity
FDY98_RS07450	COG0477	Major facilitator Superfamily
FDY98_RS07545	COG0463	Glycosyl transferase, family 2
FDY98_RS07625	COG1215	transferase activity, transferring glycosyl groups
FDY98_RS07695	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FDY98_RS07695	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FDY98_RS07705	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FDY98_RS07715	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FDY98_RS07720	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FDY98_RS07735	COG0840	transmembrane signaling receptor activity
FDY98_RS07735	COG0840	transmembrane signaling receptor activity
FDY98_RS07740	COG0840	transmembrane signaling receptor activity
FDY98_RS07740	COG0840	transmembrane signaling receptor activity
FDY98_RS07755	COG0494	nUDIX hydrolase
FDY98_RS07760	COG1011	Hydrolase
FDY98_RS07765	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FDY98_RS07770	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FDY98_RS07775	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FDY98_RS07790	COG0583	DNA-binding transcription factor activity
FDY98_RS07820	COG0251	oxidation-reduction process
FDY98_RS07835	COG1129	ABC transporter
FDY98_RS07875	COG1028	Short-chain dehydrogenase reductase Sdr
FDY98_RS07940	COG0730	response to heat
FDY98_RS07945	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FDY98_RS08010	COG1088	dTDP-glucose 4,6-dehydratase activity
FDY98_RS08080	COG0438	transferase activity, transferring glycosyl groups
FDY98_RS08080	COG1216	Glycosyl transferase, family 2
FDY98_RS08085	COG0438	transferase activity, transferring glycosyl groups
FDY98_RS08085	COG1216	Glycosyl transferase, family 2
FDY98_RS08105	COG0033	Phosphoglucomutase
FDY98_RS08110	COG0471	metal ion transport
FDY98_RS08110	COG3273	potassium ion transport
FDY98_RS08125	COG0175	sulfate reduction
FDY98_RS08135	COG1218	3'(2'),5'-bisphosphate nucleotidase
FDY98_RS08165	COG0156	8-amino-7-oxononanoate synthase activity
FDY98_RS08210	COG2153	protein acetylation
FDY98_RS08255	COG1228	amidohydrolase
FDY98_RS08270	COG2986	histidine ammonia-lyase
FDY98_RS08275	COG2056	Na+-H+ antiporter family
FDY98_RS08325	COG3871	stress protein (general stress protein 26)
FDY98_RS08345	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FDY98_RS08375	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FDY98_RS08390	COG0657	acetylesterase activity
FDY98_RS08405	COG3246	L-lysine catabolic process to acetate
FDY98_RS08430	COG1802	Transcriptional regulator
FDY98_RS08435	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FDY98_RS08460	COG1063	alcohol dehydrogenase
FDY98_RS08470	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FDY98_RS08470	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FDY98_RS08515	COG1028	Short-chain dehydrogenase reductase Sdr
FDY98_RS08540	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FDY98_RS08555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FDY98_RS08560	COG1609	Transcriptional regulator
FDY98_RS08575	COG2813	Specifically methylates the guanine in position
FDY98_RS08580	COG2186	Transcriptional regulator
FDY98_RS08585	COG1028	Short-chain dehydrogenase reductase Sdr
FDY98_RS08620	COG3151	Protein conserved in bacteria
FDY98_RS08625	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FDY98_RS08630	COG0175	sulfate reduction
FDY98_RS08635	COG2895	sulfate adenylyltransferase (ATP) activity
FDY98_RS08660	COG0693	protein deglycase activity
FDY98_RS08670	COG2738	Putative neutral zinc metallopeptidase
FDY98_RS08715	COG0500	methyltransferase
FDY98_RS08725	COG0166	Belongs to the GPI family
FDY98_RS08745	COG0560	Phosphoserine phosphatase
FDY98_RS08745	COG3830	Belongs to the UPF0237 family
FDY98_RS08750	COG1320	monovalent cation:proton antiporter activity
FDY98_RS08755	COG2212	antiporter activity
FDY98_RS08760	COG1863	multisubunit Na H antiporter MnhE subunit
FDY98_RS08765	COG0651	ATP synthesis coupled electron transport
FDY98_RS08770	COG1006	Multisubunit Na H antiporter MnhC subunit
FDY98_RS08775	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FDY98_RS08775	COG2111	Na H antiporter
FDY98_RS08795	COG4993	Dehydrogenase
FDY98_RS08815	COG1509	lysine 2,3-aminomutase activity
FDY98_RS08820	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FDY98_RS08825	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FDY98_RS08840	COG1309	transcriptional regulator
FDY98_RS08855	COG1162	GTPase activity
FDY98_RS08865	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FDY98_RS08870	COG4948	Mandelate Racemase Muconate Lactonizing
FDY98_RS08875	COG1028	Short-chain dehydrogenase reductase Sdr
FDY98_RS08890	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FDY98_RS08895	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FDY98_RS08910	COG0802	atpase or kinase
FDY98_RS08915	COG0860	N-Acetylmuramoyl-L-alanine amidase
FDY98_RS08920	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FDY98_RS08925	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FDY98_RS08930	COG1923	regulation of RNA biosynthetic process
FDY98_RS08935	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FDY98_RS08940	COG0330	HflC and HflK could
FDY98_RS08945	COG0330	HflC and HflK could
FDY98_RS08950	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FDY98_RS08955	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FDY98_RS08960	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
FDY98_RS08965	COG1666	GTP binding
FDY98_RS08970	COG0308	aminopeptidase N
FDY98_RS08975	COG1597	lipid kinase activity
FDY98_RS08985	COG1278	Cold shock
FDY98_RS09015	COG2062	phosphohistidine phosphatase, SixA
FDY98_RS09020	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FDY98_RS09025	COG0154	amidase activity
FDY98_RS09075	COG0312	modulator of DNA gyrase
FDY98_RS09080	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FDY98_RS09085	COG1660	Displays ATPase and GTPase activities
FDY98_RS09105	COG1137	ATPase activity
FDY98_RS09110	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FDY98_RS09120	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FDY98_RS09130	COG1127	ABC transporter
FDY98_RS09135	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FDY98_RS09140	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FDY98_RS09165	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FDY98_RS09185	COG3105	Protein conserved in bacteria
FDY98_RS09190	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FDY98_RS09195	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FDY98_RS09205	COG0723	plastoquinol--plastocyanin reductase activity
FDY98_RS09215	COG2857	Cytochrome c1
FDY98_RS09220	COG0625	glutathione transferase activity
FDY98_RS09225	COG2969	positive regulation of protein catabolic process
FDY98_RS09230	COG2823	Periplasmic or secreted lipoprotein
FDY98_RS09235	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FDY98_RS09240	COG0792	nuclease activity
FDY98_RS09250	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FDY98_RS09260	COG0275	rRNA processing
FDY98_RS09265	COG3116	cell division
FDY98_RS09280	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FDY98_RS09290	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FDY98_RS09295	COG0772	Belongs to the SEDS family
FDY98_RS09300	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FDY98_RS09305	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FDY98_RS09310	COG1181	Belongs to the D-alanine--D-alanine ligase family
FDY98_RS09350	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FDY98_RS09360	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FDY98_RS09365	COG2957	Belongs to the agmatine deiminase family
FDY98_RS09370	COG4591	ABC-type transport system involved in lipoprotein release permease component
FDY98_RS09375	COG1136	(ABC) transporter
FDY98_RS09400	COG2835	tetraacyldisaccharide 4'-kinase activity
FDY98_RS09415	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FDY98_RS09430	COG0546	phosphoglycolate phosphatase activity
FDY98_RS09440	COG0424	maF-like protein
FDY98_RS09450	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FDY98_RS09455	COG0416	fatty acid biosynthetic process
FDY98_RS09470	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FDY98_RS09475	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FDY98_RS09485	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FDY98_RS09490	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FDY98_RS09505	COG0084	hydrolase, TatD family'
FDY98_RS09515	COG0210	DNA helicase
FDY98_RS09530	COG4251	negative regulation of phosphorylation
FDY98_RS09530	COG3706	GGDEF domain
FDY98_RS09530	COG2203	Gaf domain
FDY98_RS09530	COG5001	Diguanylate cyclase
FDY98_RS09560	COG1780	Probably involved in ribonucleotide reductase function
FDY98_RS09585	COG0494	nUDIX hydrolase
FDY98_RS09595	COG0811	peptide transport
FDY98_RS09600	COG0811	peptide transport
FDY98_RS09605	COG0848	biopolymer transport protein
FDY98_RS09620	COG0708	Exodeoxyribonuclease III
FDY98_RS09635	COG1199	ATP-dependent helicase activity
FDY98_RS09665	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FDY98_RS09670	COG0481	GTPase activity
FDY98_RS09680	COG0571	ribonuclease III activity
FDY98_RS09690	COG1381	Involved in DNA repair and RecF pathway recombination
FDY98_RS09695	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FDY98_RS09700	COG0736	holo-[acyl-carrier-protein] synthase activity
FDY98_RS09720	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FDY98_RS09725	COG3956	TIGRFAM MazG family protein
FDY98_RS09760	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
FDY98_RS09800	COG3209	COG3209 Rhs family protein
FDY98_RS09835	COG1024	Enoyl-CoA hydratase
FDY98_RS09840	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FDY98_RS09845	COG1960	acyl-CoA dehydrogenase activity
FDY98_RS09870	COG0559	Belongs to the binding-protein-dependent transport system permease family
FDY98_RS09880	COG1960	acyl-CoA dehydrogenase activity
FDY98_RS09885	COG1250	3-hydroxyacyl-CoA dehydrogenase
FDY98_RS09885	COG1024	Enoyl-CoA hydratase
FDY98_RS09935	COG2814	Major facilitator Superfamily
FDY98_RS09990	COG0765	amino acid transport
FDY98_RS09995	COG0765	amino acid transport
FDY98_RS10000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FDY98_RS10015	COG1349	DNA-binding transcription factor activity
FDY98_RS10020	COG0494	nUDIX hydrolase
FDY98_RS10095	COG3706	GGDEF domain
FDY98_RS10135	COG3706	GGDEF domain
FDY98_RS10150	COG3483	tryptophan 2,3-dioxygenase activity
FDY98_RS10155	COG1704	LemA family
FDY98_RS10165	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FDY98_RS10165	COG0456	acetyltransferase
FDY98_RS10185	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FDY98_RS10190	COG0583	DNA-binding transcription factor activity
FDY98_RS10195	COG1285	pathogenesis
FDY98_RS10235	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FDY98_RS10240	COG0653	protein targeting
FDY98_RS10245	COG2807	transmembrane transport
FDY98_RS10250	COG1047	Peptidyl-prolyl cis-trans
FDY98_RS10265	COG5001	Diguanylate cyclase
FDY98_RS10265	COG4251	negative regulation of phosphorylation
FDY98_RS10265	COG3706	GGDEF domain
FDY98_RS10265	COG2203	Gaf domain
FDY98_RS10295	COG0442	prolyl-tRNA aminoacylation
FDY98_RS10325	COG3273	potassium ion transport
FDY98_RS10325	COG0471	metal ion transport
FDY98_RS10330	COG1349	DNA-binding transcription factor activity
FDY98_RS10345	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FDY98_RS10360	COG0395	ABC-type sugar transport system, permease component
FDY98_RS10370	COG3842	ATPase activity
FDY98_RS10375	COG3842	ATPase activity
FDY98_RS10415	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDY98_RS10420	COG0842	Transport permease protein
FDY98_RS10420	COG1129	ABC transporter
FDY98_RS10455	COG1063	alcohol dehydrogenase
FDY98_RS10470	COG0045	succinate-CoA ligase (ADP-forming) activity
FDY98_RS10470	COG1042	CoA-binding domain protein
FDY98_RS10470	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FDY98_RS10485	COG3243	poly(R)-hydroxyalkanoic acid synthase
FDY98_RS10490	COG0071	Belongs to the small heat shock protein (HSP20) family
FDY98_RS10505	COG3307	-O-antigen
FDY98_RS10510	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FDY98_RS10570	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FDY98_RS10575	COG1216	Glycosyl transferase, family 2
FDY98_RS10585	COG1216	Glycosyl transferase, family 2
FDY98_RS10585	COG0463	Glycosyl transferase, family 2
FDY98_RS10595	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FDY98_RS10595	COG2755	lipolytic protein G-D-S-L family
FDY98_RS10605	COG1216	Glycosyl transferase, family 2
FDY98_RS10610	COG4451	ribulose bisphosphate carboxylase, small
FDY98_RS10610	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FDY98_RS10615	COG1321	iron dependent repressor
FDY98_RS10655	COG0459	protein refolding
FDY98_RS10660	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FDY98_RS10670	COG1028	Short-chain dehydrogenase reductase Sdr
FDY98_RS10720	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FDY98_RS10740	COG0511	ligase activity, forming carbon-carbon bonds
FDY98_RS10750	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FDY98_RS10765	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FDY98_RS10785	COG2199	diguanylate cyclase activity
FDY98_RS10785	COG2200	EAL domain
FDY98_RS10785	COG2202	Pas domain
FDY98_RS10800	COG5002	protein histidine kinase activity
FDY98_RS10800	COG2176	DNA-directed DNA polymerase activity
FDY98_RS10815	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FDY98_RS10820	COG4660	Part of a membrane complex involved in electron transport
FDY98_RS10825	COG4659	FMN binding
FDY98_RS10830	COG4658	electron transport chain
FDY98_RS10845	COG4657	Part of a membrane complex involved in electron transport
FDY98_RS10850	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FDY98_RS10850	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FDY98_RS10870	COG0824	Thioesterase
FDY98_RS10880	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FDY98_RS10935	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FDY98_RS10975	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FDY98_RS10980	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FDY98_RS11005	COG0129	dihydroxy-acid dehydratase activity
FDY98_RS11030	COG1028	Short-chain dehydrogenase reductase Sdr
FDY98_RS11040	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FDY98_RS11060	COG0640	Transcriptional regulator
FDY98_RS11080	COG0028	Belongs to the TPP enzyme family
FDY98_RS11100	COG1012	belongs to the aldehyde dehydrogenase family
FDY98_RS11120	COG0583	DNA-binding transcription factor activity
FDY98_RS11130	COG0583	DNA-binding transcription factor activity
FDY98_RS11135	COG1335	isochorismatase
FDY98_RS11160	COG3850	Histidine kinase
FDY98_RS11165	COG2197	response regulator
FDY98_RS11170	COG2207	Transcriptional regulator
FDY98_RS11200	COG0655	NAD(P)H dehydrogenase (quinone) activity
FDY98_RS11215	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FDY98_RS11290	COG2186	Transcriptional regulator
FDY98_RS11310	COG1764	response to oxidative stress
FDY98_RS11320	COG1733	regulation of RNA biosynthetic process
FDY98_RS11350	COG2223	nitrite transmembrane transporter activity
FDY98_RS11365	COG2197	response regulator
FDY98_RS11395	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FDY98_RS11425	COG3189	MarR family transcriptional regulator
FDY98_RS11445	COG0714	Associated with various cellular activities
FDY98_RS11465	COG1845	cytochrome c oxidase, subunit III
FDY98_RS11470	COG3154	lipid carrier protein
FDY98_RS11475	COG1017	nitric oxide dioxygenase activity
FDY98_RS11475	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FDY98_RS11490	COG1959	2 iron, 2 sulfur cluster binding
FDY98_RS11495	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FDY98_RS11515	COG0826	peptidase U32
FDY98_RS11530	COG1140	nitrate reductase beta subunit
FDY98_RS11535	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FDY98_RS11540	COG2181	nitrate reductase activity
FDY98_RS11545	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FDY98_RS11555	COG0303	'Molybdopterin
FDY98_RS11565	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FDY98_RS11585	COG1611	Belongs to the LOG family
FDY98_RS11590	COG0583	DNA-binding transcription factor activity
FDY98_RS11600	COG0509	glycine decarboxylation via glycine cleavage system
FDY98_RS11630	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FDY98_RS11655	COG1028	Short-chain dehydrogenase reductase Sdr
FDY98_RS11660	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FDY98_RS11665	COG4191	Histidine kinase
FDY98_RS11670	COG0418	dihydroorotase activity
FDY98_RS11675	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FDY98_RS11680	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FDY98_RS11725	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FDY98_RS11730	COG0084	hydrolase, TatD family'
FDY98_RS11735	COG0354	folic acid binding
FDY98_RS11755	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FDY98_RS11765	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FDY98_RS11770	COG0583	DNA-binding transcription factor activity
FDY98_RS11790	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FDY98_RS11810	COG0632	four-way junction helicase activity
FDY98_RS11815	COG2255	four-way junction helicase activity
FDY98_RS11820	COG0824	Thioesterase
FDY98_RS11840	COG0823	Involved in the tonB-independent uptake of proteins
FDY98_RS11845	COG2885	chlorophyll binding
FDY98_RS11855	COG1028	Short-chain dehydrogenase reductase Sdr
FDY98_RS11865	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FDY98_RS11870	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FDY98_RS11895	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FDY98_RS11905	COG0288	reversible hydration of carbon dioxide
FDY98_RS11915	COG0456	acetyltransferase
FDY98_RS11920	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FDY98_RS11925	COG1917	Cupin 2, conserved barrel domain protein
FDY98_RS11930	COG0189	ligase activity
FDY98_RS11930	COG4067	protein conserved in archaea
FDY98_RS11945	COG0735	belongs to the Fur family
FDY98_RS11950	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FDY98_RS11955	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FDY98_RS11960	COG2166	iron-sulfur cluster assembly
FDY98_RS11975	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FDY98_RS11975	COG0316	Belongs to the HesB IscA family
FDY98_RS11985	COG0534	Mate efflux family protein
FDY98_RS12055	COG2923	Belongs to the DsrF TusC family
FDY98_RS12130	COG2204	response regulator
FDY98_RS12245	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FDY98_RS12280	COG1172	Belongs to the binding-protein-dependent transport system permease family
FDY98_RS12285	COG1028	Short-chain dehydrogenase reductase Sdr
FDY98_RS12295	COG1609	Transcriptional regulator
FDY98_RS12305	COG0450	alkyl hydroperoxide reductase
FDY98_RS12310	COG3453	Protein conserved in bacteria
FDY98_RS12310	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FDY98_RS12415	COG1028	Short-chain dehydrogenase reductase Sdr
FDY98_RS12450	COG0318	PFAM AMP-dependent synthetase and ligase
FDY98_RS12460	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FDY98_RS12465	COG1960	acyl-CoA dehydrogenase activity
FDY98_RS12470	COG1846	Transcriptional regulator
FDY98_RS12480	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FDY98_RS12495	COG1063	alcohol dehydrogenase
FDY98_RS12500	COG1028	Short-chain dehydrogenase reductase Sdr
FDY98_RS12510	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FDY98_RS12525	COG1414	Transcriptional regulator
FDY98_RS12545	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FDY98_RS12615	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FDY98_RS12700	COG0596	Alpha beta hydrolase
FDY98_RS12705	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FDY98_RS12715	COG0640	Transcriptional regulator
FDY98_RS12720	COG0616	signal peptide processing
FDY98_RS12730	COG2816	NAD+ diphosphatase activity
FDY98_RS12735	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FDY98_RS12740	COG0328	RNA-DNA hybrid ribonuclease activity
FDY98_RS12750	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FDY98_RS12755	COG1388	LysM domain
FDY98_RS12755	COG0741	lytic transglycosylase activity
FDY98_RS12790	COG2962	Rard protein
FDY98_RS12815	COG1024	Enoyl-CoA hydratase
FDY98_RS12820	COG1960	acyl-CoA dehydrogenase activity
FDY98_RS12830	COG1024	Enoyl-CoA hydratase
FDY98_RS12860	COG0318	PFAM AMP-dependent synthetase and ligase
FDY98_RS12865	COG1960	acyl-CoA dehydrogenase activity
FDY98_RS12885	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FDY98_RS12905	COG0515	serine threonine protein kinase
FDY98_RS12915	COG0508	dehydrogenase complex catalyzes the overall conversion of
FDY98_RS12920	COG0022	dehydrogenase e1 component
FDY98_RS12930	COG1174	glycine betaine transport
FDY98_RS12935	COG1125	glycine betaine transport
FDY98_RS12940	COG1174	glycine betaine transport
FDY98_RS12945	COG1732	Glycine betaine
FDY98_RS12950	COG0215	cysteine-tRNA ligase activity
FDY98_RS12960	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FDY98_RS12965	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FDY98_RS12970	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FDY98_RS12985	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FDY98_RS12990	COG0740	serine-type endopeptidase activity
FDY98_RS12995	COG0544	peptidyl-prolyl cis-trans isomerase activity
FDY98_RS13005	COG0716	FMN binding
FDY98_RS13015	COG0776	regulation of translation
FDY98_RS13020	COG0072	phenylalanine-tRNA ligase activity
FDY98_RS13025	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FDY98_RS13030	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FDY98_RS13035	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FDY98_RS13040	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FDY98_RS13045	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FDY98_RS13060	COG0109	protoheme IX farnesyltransferase activity
FDY98_RS13090	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FDY98_RS13120	COG1309	transcriptional regulator
FDY98_RS13175	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FDY98_RS13210	COG3009	Protein conserved in bacteria
FDY98_RS13220	COG0513	Belongs to the DEAD box helicase family
FDY98_RS13230	COG2807	transmembrane transport
FDY98_RS13235	COG0252	asparaginase activity
FDY98_RS13255	COG0602	queuosine metabolic process
FDY98_RS13285	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FDY98_RS13290	COG0584	glycerophosphoryl diester phosphodiesterase
FDY98_RS13310	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FDY98_RS13320	COG1376	ErfK ybiS ycfS ynhG family protein
FDY98_RS13325	COG1309	transcriptional regulator
FDY98_RS13330	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FDY98_RS13350	COG0314	molybdopterin synthase activity
FDY98_RS13355	COG0315	cyclic pyranopterin monophosphate synthase activity
FDY98_RS13360	COG1763	Mo-molybdopterin cofactor biosynthetic process
FDY98_RS13370	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FDY98_RS13375	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FDY98_RS13380	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FDY98_RS13385	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FDY98_RS13395	COG0307	riboflavin synthase, alpha
FDY98_RS13400	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FDY98_RS13405	COG2011	ABC-type metal ion transport system permease component
FDY98_RS13410	COG1464	Belongs to the NlpA lipoprotein family
FDY98_RS13415	COG1956	GAF domain-containing protein
FDY98_RS13450	COG0628	permease
FDY98_RS13460	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FDY98_RS13465	COG0717	Belongs to the dCTP deaminase family
FDY98_RS13470	COG0489	protein tyrosine kinase activity
FDY98_RS13480	COG1648	precorrin-2 dehydrogenase activity
FDY98_RS13480	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FDY98_RS13490	COG2154	pterin-4-alpha-carbinolamine dehydratase
FDY98_RS13505	COG0534	Mate efflux family protein
FDY98_RS13510	COG2353	YceI-like domain
FDY98_RS13515	COG3038	cytochrome b561
FDY98_RS13555	COG0159	tryptophan synthase activity
FDY98_RS13565	COG0135	phosphoribosylanthranilate isomerase activity
FDY98_RS13570	COG0101	tRNA pseudouridine synthase activity
FDY98_RS13585	COG0473	3-isopropylmalate dehydrogenase activity
FDY98_RS13590	COG0066	3-isopropylmalate dehydratase activity
FDY98_RS13595	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FDY98_RS13605	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FDY98_RS13680	COG2818	Glycosylase
FDY98_RS13710	COG0456	acetyltransferase
FDY98_RS13715	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
FDY98_RS13785	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FDY98_RS13790	COG0583	DNA-binding transcription factor activity
FDY98_RS13810	COG4974	Belongs to the 'phage' integrase family
FDY98_RS13830	COG0495	leucyl-tRNA aminoacylation
FDY98_RS13910	COG1388	LysM domain
FDY98_RS13910	COG1376	ErfK ybiS ycfS ynhG family protein
FDY98_RS13945	COG0583	DNA-binding transcription factor activity
FDY98_RS13950	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FDY98_RS13960	COG2921	Belongs to the UPF0250 family
FDY98_RS13965	COG1686	Belongs to the peptidase S11 family
FDY98_RS13975	COG2951	lytic endotransglycosylase activity
FDY98_RS13980	COG0772	Belongs to the SEDS family
FDY98_RS13985	COG0768	penicillin binding
FDY98_RS13990	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FDY98_RS14000	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FDY98_RS14005	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FDY98_RS14020	COG0586	Pfam SNARE associated Golgi protein
FDY98_RS14025	COG1280	lysine exporter protein (LysE YggA)
FDY98_RS14035	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FDY98_RS14075	COG0583	DNA-binding transcription factor activity
FDY98_RS14090	COG1063	alcohol dehydrogenase
FDY98_RS14105	COG0542	response to heat
FDY98_RS14135	COG1609	Transcriptional regulator
FDY98_RS14150	COG1177	transmembrane transport
FDY98_RS14160	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FDY98_RS14165	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FDY98_RS14190	COG2329	Antibiotic biosynthesis monooxygenase
FDY98_RS14225	COG0456	acetyltransferase
FDY98_RS14225	COG1846	Transcriptional regulator
FDY98_RS14410	COG2875	Belongs to the precorrin methyltransferase family
FDY98_RS14460	COG1797	cobyrinic acid a,c-diamide synthase activity
FDY98_RS14480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FDY98_RS14485	COG1120	ATPase activity
FDY98_RS14505	COG0113	porphobilinogen synthase activity
FDY98_RS14515	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FDY98_RS14520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FDY98_RS14530	COG4206	TonB-dependent receptor
FDY98_RS14545	COG0406	alpha-ribazole phosphatase activity
FDY98_RS14550	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FDY98_RS14560	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FDY98_RS14565	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FDY98_RS14570	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FDY98_RS14580	COG0837	glucose binding
FDY98_RS14590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FDY98_RS14600	COG4948	Mandelate Racemase Muconate Lactonizing
FDY98_RS14605	COG3734	2-keto-3-deoxy-galactonokinase
FDY98_RS14620	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FDY98_RS14645	COG0569	domain protein
FDY98_RS14655	COG2182	Extracellular solute-binding protein
FDY98_RS14665	COG3833	ABC-type maltose transport systems, permease component
FDY98_RS14680	COG2205	protein histidine kinase activity
FDY98_RS14685	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FDY98_RS14710	COG1595	DNA-templated transcription, initiation
FDY98_RS14755	COG0366	Alpha amylase catalytic
FDY98_RS14760	COG3842	ATPase activity
FDY98_RS14780	COG1803	Methylglyoxal synthase
FDY98_RS14790	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FDY98_RS14790	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FDY98_RS14795	COG1105	Belongs to the carbohydrate kinase PfkB family
FDY98_RS14805	COG0166	Belongs to the GPI family
FDY98_RS14825	COG1028	Short-chain dehydrogenase reductase Sdr
FDY98_RS14900	COG0401	homolog of Blt101
FDY98_RS14905	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FDY98_RS14905	COG0617	tRNA 3'-terminal CCA addition
FDY98_RS14905	COG0517	IMP dehydrogenase activity
FDY98_RS14945	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FDY98_RS14945	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FDY98_RS14950	COG0739	heme binding
FDY98_RS14960	COG0789	Transcriptional regulator
FDY98_RS14965	COG2217	Heavy metal translocating P-type atpase
FDY98_RS14975	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FDY98_RS15000	COG1959	2 iron, 2 sulfur cluster binding
FDY98_RS15035	COG0655	NAD(P)H dehydrogenase (quinone) activity
FDY98_RS15040	COG0583	DNA-binding transcription factor activity
FDY98_RS15080	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FDY98_RS15095	COG2363	Small membrane protein
FDY98_RS15110	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FDY98_RS15135	COG1999	signal sequence binding
FDY98_RS15145	COG0545	Peptidyl-prolyl cis-trans isomerase
FDY98_RS15150	COG0589	response to stress
FDY98_RS15165	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FDY98_RS15180	COG1490	D-aminoacyl-tRNA deacylase activity
FDY98_RS15225	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FDY98_RS15230	COG1011	Hydrolase
FDY98_RS15235	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FDY98_RS15250	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FDY98_RS15260	COG0165	Argininosuccinate lyase
FDY98_RS15290	COG1970	mechanosensitive ion channel activity
FDY98_RS15295	COG0589	response to stress
FDY98_RS15310	COG3135	benzoate transporter
FDY98_RS15320	COG0411	ABC transporter
FDY98_RS15335	COG0683	leucine binding
FDY98_RS15385	COG4829	muconolactone delta-isomerase
FDY98_RS15390	COG4948	Mandelate Racemase Muconate Lactonizing
FDY98_RS15415	COG3246	L-lysine catabolic process to acetate
FDY98_RS15420	COG0471	metal ion transport
FDY98_RS15425	COG3039	Transposase
FDY98_RS15430	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FDY98_RS15445	COG1335	isochorismatase
FDY98_RS15480	COG0179	Fumarylacetoacetate (FAA) hydrolase
FDY98_RS15495	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FDY98_RS15505	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FDY98_RS15535	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FDY98_RS15550	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FDY98_RS15570	COG1012	belongs to the aldehyde dehydrogenase family
FDY98_RS15585	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FDY98_RS15590	COG3485	protocatechuate 3,4-dioxygenase
FDY98_RS15595	COG3485	protocatechuate 3,4-dioxygenase
FDY98_RS15600	COG0583	DNA-binding transcription factor activity
FDY98_RS15605	COG0596	Alpha beta hydrolase
FDY98_RS15610	COG0183	Belongs to the thiolase family
FDY98_RS15615	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FDY98_RS15620	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FDY98_RS15635	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FDY98_RS15645	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FDY98_RS15650	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FDY98_RS15650	COG1082	Xylose isomerase domain protein TIM barrel
FDY98_RS15655	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FDY98_RS15670	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FDY98_RS15680	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FDY98_RS15695	COG1028	Short-chain dehydrogenase reductase Sdr
FDY98_RS15735	COG3181	Tripartite tricarboxylate transporter family receptor
FDY98_RS15740	COG0673	inositol 2-dehydrogenase activity
FDY98_RS15745	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FDY98_RS15750	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FDY98_RS15780	COG1414	Transcriptional regulator
FDY98_RS15790	COG0733	neurotransmitter:sodium symporter activity
FDY98_RS15800	COG1737	Transcriptional regulator
FDY98_RS15805	COG0210	DNA helicase
FDY98_RS15810	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FDY98_RS15835	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FDY98_RS15840	COG0704	Plays a role in the regulation of phosphate uptake
FDY98_RS15880	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FDY98_RS15885	COG3161	chorismate lyase activity
FDY98_RS15905	COG0583	DNA-binding transcription factor activity
FDY98_RS15910	COG1012	belongs to the aldehyde dehydrogenase family
FDY98_RS15920	COG1473	amidohydrolase
FDY98_RS15935	COG1289	transmembrane transporter activity
FDY98_RS15945	COG0583	DNA-binding transcription factor activity
FDY98_RS15965	COG1758	RNA polymerase activity
FDY98_RS15970	COG0194	GDP metabolic process
FDY98_RS16020	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
FDY98_RS16030	COG3039	Transposase
FDY98_RS16060	COG1561	YicC-like family, N-terminal region
FDY98_RS16080	COG1172	Belongs to the binding-protein-dependent transport system permease family
FDY98_RS16095	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FDY98_RS16125	COG1177	transmembrane transport
FDY98_RS16130	COG1176	ABC-type spermidine putrescine transport system, permease component I
FDY98_RS16165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FDY98_RS16175	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FDY98_RS16180	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FDY98_RS16185	COG0210	DNA helicase
FDY98_RS16195	COG0456	acetyltransferase
FDY98_RS16215	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FDY98_RS16225	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FDY98_RS16235	COG1968	undecaprenyl-diphosphatase activity
FDY98_RS16250	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FDY98_RS16255	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FDY98_RS16260	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FDY98_RS16265	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FDY98_RS16270	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FDY98_RS16275	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FDY98_RS16285	COG0356	it plays a direct role in the translocation of protons across the membrane
FDY98_RS16295	COG1475	DNA binding
FDY98_RS16300	COG1192	Involved in chromosome partitioning
FDY98_RS16305	COG0357	Ribosomal RNA small subunit methyltransferase G
FDY98_RS16310	COG0445	tRNA wobble uridine modification
FDY98_RS16320	COG0765	amino acid transport
FDY98_RS16325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FDY98_RS16330	COG0316	Belongs to the HesB IscA family
FDY98_RS16335	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FDY98_RS16345	COG1981	membrane
FDY98_RS16350	COG0351	phosphomethylpyrimidine kinase
FDY98_RS16355	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FDY98_RS16410	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FDY98_RS16430	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FDY98_RS16435	COG1192	Involved in chromosome partitioning
FDY98_RS16445	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FDY98_RS16460	COG0469	pyruvate kinase activity
FDY98_RS16470	COG3257	ureidoglycine aminohydrolase activity
FDY98_RS16520	COG1953	Uracil, thiamine, allantoin
FDY98_RS16540	COG3609	addiction module antidote protein, CC2985 family
FDY98_RS16560	COG2351	hydroxyisourate hydrolase activity
FDY98_RS16580	COG0625	glutathione transferase activity
FDY98_RS16600	COG0247	lactate metabolic process
FDY98_RS16600	COG0277	FAD linked oxidase domain protein
FDY98_RS16615	COG1024	Enoyl-CoA hydratase
FDY98_RS16640	COG1802	Transcriptional regulator
FDY98_RS16645	COG2186	Transcriptional regulator
FDY98_RS16650	COG0277	FAD linked oxidase domain protein
FDY98_RS16655	COG0277	FAD linked oxidase domain protein
FDY98_RS16660	COG0247	lactate metabolic process
FDY98_RS16665	COG3193	protein, possibly involved in utilization of glycolate and propanediol
FDY98_RS16700	COG3278	Belongs to the heme-copper respiratory oxidase family
FDY98_RS16720	COG0348	domain, Protein
FDY98_RS16750	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FDY98_RS16755	COG0037	tRNA processing
FDY98_RS16775	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FDY98_RS16825	COG0563	adenylate kinase activity
FDY98_RS16840	COG3023	N-Acetylmuramoyl-L-alanine amidase
FDY98_RS16860	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FDY98_RS16875	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FDY98_RS16885	COG0425	Belongs to the sulfur carrier protein TusA family
FDY98_RS16895	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FDY98_RS16910	COG1187	pseudouridine synthase activity
FDY98_RS16920	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FDY98_RS16940	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FDY98_RS16950	COG1946	Acyl-CoA thioesterase
FDY98_RS16955	COG0281	malic enzyme
FDY98_RS16960	COG0254	rRNA binding
FDY98_RS16970	COG0018	arginyl-trna synthetase
FDY98_RS16980	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FDY98_RS16985	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FDY98_RS17015	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FDY98_RS17020	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FDY98_RS17045	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FDY98_RS17060	COG0745	RESPONSE REGULATOR receiver
FDY98_RS17090	COG3706	GGDEF domain
FDY98_RS17120	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FDY98_RS17135	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FDY98_RS17145	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FDY98_RS17150	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FDY98_RS17155	COG0534	Mate efflux family protein
FDY98_RS17160	COG2031	fatty acid transporter
FDY98_RS17165	COG1607	acyl-coa hydrolase
FDY98_RS17175	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FDY98_RS17225	COG0783	Belongs to the Dps family
FDY98_RS17240	COG1444	tRNA N-acetyltransferase activity
FDY98_RS17290	COG1294	oxidase, subunit
FDY98_RS17320	COG0179	Fumarylacetoacetate (FAA) hydrolase
FDY98_RS17355	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FDY98_RS17375	COG0131	Imidazoleglycerol-phosphate dehydratase
FDY98_RS17390	COG0107	imidazoleglycerol-phosphate synthase activity
FDY98_RS17400	COG3068	Protein conserved in bacteria
FDY98_RS17410	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
FDY98_RS17415	COG0709	Synthesizes selenophosphate from selenide and ATP
FDY98_RS17420	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FDY98_RS17430	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FDY98_RS17450	COG1183	phosphatidylcholine synthase activity
FDY98_RS17455	COG0440	acetolactate synthase activity
FDY98_RS17460	COG0028	Belongs to the TPP enzyme family
FDY98_RS17490	COG0840	transmembrane signaling receptor activity
FDY98_RS17530	COG0281	malic enzyme
FDY98_RS17535	COG2391	methyltransferase activity
FDY98_RS17585	COG5444	nuclease activity
FDY98_RS17700	COG0180	Tryptophanyl-tRNA synthetase
FDY98_RS17715	COG4966	pilus assembly protein PilW
FDY98_RS17730	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FDY98_RS17735	COG1047	Peptidyl-prolyl cis-trans
FDY98_RS17745	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FDY98_RS17750	COG0196	riboflavin kinase activity
FDY98_RS17760	COG0268	Binds directly to 16S ribosomal RNA
FDY98_RS17805	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FDY98_RS17810	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FDY98_RS17905	COG0395	ABC-type sugar transport system, permease component
FDY98_RS17920	COG1028	Short-chain dehydrogenase reductase Sdr
FDY98_RS17925	COG0673	inositol 2-dehydrogenase activity
FDY98_RS17935	COG1879	ABC-type sugar transport system periplasmic component
FDY98_RS17940	COG1172	Belongs to the binding-protein-dependent transport system permease family
FDY98_RS18045	COG2084	Dehydrogenase
FDY98_RS18075	COG0129	dihydroxy-acid dehydratase activity
FDY98_RS18080	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FDY98_RS18085	COG2186	Transcriptional regulator
FDY98_RS18090	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FDY98_RS18095	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FDY98_RS18100	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FDY98_RS18105	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FDY98_RS18110	COG3395	kinase activity
FDY98_RS18115	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FDY98_RS18120	COG1028	Short-chain dehydrogenase reductase Sdr
FDY98_RS18135	COG0277	FAD linked oxidase domain protein
FDY98_RS18145	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FDY98_RS18155	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FDY98_RS18160	COG0583	DNA-binding transcription factor activity
FDY98_RS18165	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FDY98_RS18170	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FDY98_RS18195	COG3829	transcription factor binding
FDY98_RS18195	COG3290	protein histidine kinase activity
FDY98_RS18210	COG1175	transmembrane transport
FDY98_RS18250	COG1309	transcriptional regulator
FDY98_RS18255	COG2814	Major facilitator Superfamily
FDY98_RS18270	COG0235	Class ii aldolase
FDY98_RS18280	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
FDY98_RS18300	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FDY98_RS18325	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FDY98_RS18335	COG2814	Major facilitator Superfamily
FDY98_RS18340	COG4977	sequence-specific DNA binding
FDY98_RS18370	COG0318	PFAM AMP-dependent synthetase and ligase
FDY98_RS18405	COG0840	transmembrane signaling receptor activity
FDY98_RS18415	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FDY98_RS18470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FDY98_RS18475	COG0521	Mo-molybdopterin cofactor biosynthetic process
FDY98_RS18490	COG0437	4 iron, 4 sulfur cluster binding
FDY98_RS18525	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FDY98_RS18530	COG0746	molybdenum cofactor guanylyltransferase activity
FDY98_RS18545	COG0523	cobalamin synthesis protein
FDY98_RS18560	COG1953	Uracil, thiamine, allantoin
FDY98_RS18585	COG4607	ABC-type enterochelin transport system periplasmic component
FDY98_RS18590	COG0840	transmembrane signaling receptor activity
FDY98_RS18610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FDY98_RS18620	COG3300	MHYT domain
FDY98_RS18620	COG5001	Diguanylate cyclase
FDY98_RS18635	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FDY98_RS18640	COG0456	acetyltransferase
FDY98_RS18655	COG2818	Glycosylase
FDY98_RS18670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FDY98_RS18680	COG0384	phenazine biosynthesis protein PhzF
FDY98_RS18685	COG0071	Belongs to the small heat shock protein (HSP20) family
FDY98_RS18700	COG1830	Aldolase
FDY98_RS18710	COG1120	ATPase activity
FDY98_RS18745	COG1280	lysine exporter protein (LysE YggA)
FDY98_RS18750	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FDY98_RS18755	COG1522	sequence-specific DNA binding
FDY98_RS18760	COG1309	transcriptional regulator
FDY98_RS18780	COG0318	PFAM AMP-dependent synthetase and ligase
FDY98_RS18795	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FDY98_RS18805	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FDY98_RS18810	COG1053	succinate dehydrogenase
FDY98_RS18825	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FDY98_RS18840	COG1575	Belongs to the MenA family. Type 1 subfamily
FDY98_RS18845	COG2329	Antibiotic biosynthesis monooxygenase
FDY98_RS18860	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FDY98_RS18915	COG0174	glutamine synthetase
FDY98_RS18920	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FDY98_RS18935	COG1288	antiporter activity
FDY98_RS18955	COG1902	pentaerythritol trinitrate reductase activity
FDY98_RS18960	COG2957	Belongs to the agmatine deiminase family
FDY98_RS18970	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FDY98_RS18980	COG1012	belongs to the aldehyde dehydrogenase family
FDY98_RS19000	COG0488	(ABC) transporter
FDY98_RS19030	COG1960	acyl-CoA dehydrogenase activity
FDY98_RS19045	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FDY98_RS19055	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FDY98_RS19060	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
FDY98_RS19070	COG4215	(ABC) transporter
FDY98_RS19075	COG0765	amino acid transport
FDY98_RS19095	COG4221	oxidoreductase activity
FDY98_RS19100	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FDY98_RS19135	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FDY98_RS19140	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FDY98_RS19145	COG3622	Belongs to the hyi family
FDY98_RS19150	COG0235	Class ii aldolase
FDY98_RS19155	COG3395	kinase activity
FDY98_RS19165	COG1609	Transcriptional regulator
FDY98_RS19180	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FDY98_RS19190	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FDY98_RS19200	COG2186	Transcriptional regulator
FDY98_RS19205	COG0583	DNA-binding transcription factor activity
FDY98_RS19210	COG0702	epimerase
FDY98_RS19220	COG0583	DNA-binding transcription factor activity
FDY98_RS19240	COG4771	TonB-dependent receptor
FDY98_RS19245	COG3720	iron ion transport
FDY98_RS19250	COG4558	Periplasmic binding protein
FDY98_RS19255	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FDY98_RS19260	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FDY98_RS19265	COG2832	Protein of unknown function (DUF454)
FDY98_RS19270	COG1522	sequence-specific DNA binding
FDY98_RS19275	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FDY98_RS19285	COG2239	Acts as a magnesium transporter
FDY98_RS19290	COG0673	inositol 2-dehydrogenase activity
FDY98_RS19310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FDY98_RS19340	COG0673	inositol 2-dehydrogenase activity
FDY98_RS19345	COG3718	enzyme involved in inositol metabolism
FDY98_RS19360	COG3209	COG3209 Rhs family protein
FDY98_RS19365	COG3209	COG3209 Rhs family protein
FDY98_RS19390	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FDY98_RS19410	COG1840	ABC-type Fe3 transport system, periplasmic component
FDY98_RS19415	COG2188	Transcriptional regulator
FDY98_RS19455	COG0583	DNA-binding transcription factor activity
FDY98_RS19460	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FDY98_RS19465	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FDY98_RS19470	COG1984	allophanate hydrolase subunit 2
FDY98_RS19475	COG2309	aminopeptidase activity
FDY98_RS19480	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FDY98_RS19495	COG2080	2 iron, 2 sulfur cluster binding
FDY98_RS19505	COG0596	Alpha beta hydrolase
FDY98_RS19510	COG3473	Maleate cis-trans isomerase
FDY98_RS19515	COG1335	isochorismatase
FDY98_RS19520	COG1846	Transcriptional regulator
FDY98_RS19525	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FDY98_RS19525	COG2010	Cytochrome c
FDY98_RS19580	COG0583	DNA-binding transcription factor activity
FDY98_RS19600	COG3473	Maleate cis-trans isomerase
FDY98_RS19605	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FDY98_RS19625	COG3842	ATPase activity
FDY98_RS19645	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FDY98_RS19650	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FDY98_RS19670	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FDY98_RS19715	COG5002	protein histidine kinase activity
FDY98_RS19720	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FDY98_RS19735	COG0010	Belongs to the arginase family
FDY98_RS19740	COG2873	o-acetylhomoserine
FDY98_RS19755	COG0348	domain, Protein
FDY98_RS19760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FDY98_RS19780	COG0446	pyridine nucleotide-disulphide oxidoreductase
FDY98_RS19780	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FDY98_RS19795	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FDY98_RS19830	COG1063	alcohol dehydrogenase
FDY98_RS19835	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FDY98_RS19915	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FDY98_RS19920	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FDY98_RS19935	COG1024	Enoyl-CoA hydratase
FDY98_RS19945	COG2050	protein possibly involved in aromatic compounds catabolism
FDY98_RS19955	COG3396	Phenylacetate-CoA oxygenase
FDY98_RS19960	COG3460	Phenylacetate-CoA oxygenase
FDY98_RS19970	COG2151	metal-sulfur cluster biosynthetic enzyme
FDY98_RS19975	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FDY98_RS19980	COG1012	belongs to the aldehyde dehydrogenase family
FDY98_RS19980	COG2030	dehydratase
FDY98_RS20000	COG1846	Transcriptional regulator
FDY98_RS20010	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FDY98_RS20010	COG0446	pyridine nucleotide-disulphide oxidoreductase
FDY98_RS20020	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FDY98_RS20030	COG0625	glutathione transferase activity
FDY98_RS20035	COG2814	Major facilitator Superfamily
FDY98_RS20060	COG1522	sequence-specific DNA binding
FDY98_RS20085	COG1414	Transcriptional regulator
FDY98_RS20095	COG1053	succinate dehydrogenase
FDY98_RS20105	COG1012	belongs to the aldehyde dehydrogenase family
FDY98_RS20120	COG2084	Dehydrogenase
FDY98_RS20125	COG3386	PFAM SMP-30 Gluconolaconase
FDY98_RS20135	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FDY98_RS20145	COG1028	Short-chain dehydrogenase reductase Sdr
FDY98_RS20150	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FDY98_RS20155	COG0625	glutathione transferase activity
FDY98_RS20185	COG4791	protein targeting
FDY98_RS20190	COG4794	Type iii secretion
FDY98_RS20195	COG4790	Type iii secretion
FDY98_RS20200	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FDY98_RS20260	COG4789	Type iii secretion
FDY98_RS20285	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FDY98_RS20320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FDY98_RS20325	COG0583	DNA-binding transcription factor activity
FDY98_RS20330	COG2801	Transposase and inactivated derivatives
FDY98_RS20350	COG3195	allantoin biosynthetic process
FDY98_RS20350	COG3648	Uricase
FDY98_RS20370	COG0469	pyruvate kinase activity
FDY98_RS20380	COG2084	Dehydrogenase
FDY98_RS20385	COG3622	Belongs to the hyi family
FDY98_RS20390	COG3960	tartronate-semialdehyde synthase activity
FDY98_RS20395	COG3257	ureidoglycine aminohydrolase activity
FDY98_RS20400	COG1414	Transcriptional regulator
FDY98_RS20440	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FDY98_RS20445	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FDY98_RS20525	COG2188	Transcriptional regulator
FDY98_RS20540	COG1028	Short-chain dehydrogenase reductase Sdr
FDY98_RS20545	COG1028	Short-chain dehydrogenase reductase Sdr
FDY98_RS20560	COG2188	Transcriptional regulator
FDY98_RS20580	COG0523	cobalamin synthesis protein
FDY98_RS20590	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FDY98_RS20645	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FDY98_RS20655	COG0277	FAD linked oxidase domain protein
FDY98_RS20660	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FDY98_RS20665	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FDY98_RS20665	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FDY98_RS20690	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FDY98_RS20710	COG3383	formate dehydrogenase (NAD+) activity
FDY98_RS20715	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FDY98_RS20730	COG1959	2 iron, 2 sulfur cluster binding
FDY98_RS20730	COG1295	ribonuclease BN
FDY98_RS20735	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FDY98_RS20745	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FDY98_RS20755	COG0832	Belongs to the urease beta subunit family
FDY98_RS20760	COG0831	urea catabolic process
FDY98_RS20765	COG0829	nickel cation binding
FDY98_RS20775	COG0803	Belongs to the bacterial solute-binding protein 9 family
FDY98_RS20780	COG1121	(ABC) transporter
FDY98_RS20785	COG1321	iron dependent repressor
FDY98_RS20785	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FDY98_RS20835	COG4565	transcriptional regulatory protein
FDY98_RS20840	COG3290	protein histidine kinase activity
FDY98_RS20850	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FDY98_RS20855	COG1116	anion transmembrane transporter activity
FDY98_RS20865	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FDY98_RS20875	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FDY98_RS20880	COG1028	Short-chain dehydrogenase reductase Sdr
FDY98_RS20885	COG0668	transmembrane transport
FDY98_RS20890	COG1238	metal cluster binding
FDY98_RS20915	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FDY98_RS20920	COG1722	exodeoxyribonuclease VII activity
FDY98_RS20925	COG0142	geranyltranstransferase activity
FDY98_RS20930	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FDY98_RS20935	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FDY98_RS20940	COG4221	oxidoreductase activity
FDY98_RS20945	COG2207	Transcriptional regulator
FDY98_RS20960	COG1272	protein, Hemolysin III
FDY98_RS20980	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FDY98_RS20990	COG1129	ABC transporter
FDY98_RS21020	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FDY98_RS21025	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FDY98_RS21030	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FDY98_RS21035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FDY98_RS21040	COG4597	amino acid ABC transporter
FDY98_RS21050	COG1126	abc transporter atp-binding protein
FDY98_RS21055	COG0251	oxidation-reduction process
FDY98_RS21080	COG3639	organic phosphonate transmembrane transporter activity
FDY98_RS21095	COG0840	transmembrane signaling receptor activity
FDY98_RS21100	COG0840	transmembrane signaling receptor activity
FDY98_RS21105	COG0583	DNA-binding transcription factor activity
FDY98_RS21120	COG0004	ammonium transporteR
FDY98_RS21175	COG2002	toxin-antitoxin pair type II binding
FDY98_RS21195	COG1230	cation diffusion facilitator family transporter
FDY98_RS21200	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FDY98_RS21200	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FDY98_RS21205	COG0739	heme binding
FDY98_RS21215	COG0789	Transcriptional regulator
FDY98_RS21255	COG1959	2 iron, 2 sulfur cluster binding
FDY98_RS21280	COG2161	toxin-antitoxin pair type II binding
FDY98_RS21310	COG3098	single-species biofilm formation
FDY98_RS21335	COG2949	membrane
FDY98_RS21355	COG0396	ATPase activity
FDY98_RS21375	COG2824	Alkylphosphonate utilization operon protein PhnA
FDY98_RS21400	COG0183	Belongs to the thiolase family
FDY98_RS21415	COG1846	Transcriptional regulator
FDY98_RS21465	COG0084	hydrolase, TatD family'
FDY98_RS21475	COG3101	peptidyl-lysine hydroxylation
FDY98_RS21500	COG2329	Antibiotic biosynthesis monooxygenase
FDY98_RS21505	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
FDY98_RS21550	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FDY98_RS21555	COG0840	transmembrane signaling receptor activity
FDY98_RS21565	COG0431	NADPH-dependent FMN reductase
FDY98_RS21570	COG0798	PFAM Bile acid sodium symporter
FDY98_RS21590	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FDY98_RS21670	COG2983	Belongs to the UPF0260 family
FDY98_RS21680	COG3100	YcgL domain-containing protein
FDY98_RS21690	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FDY98_RS21695	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FDY98_RS21700	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FDY98_RS21705	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FDY98_RS21725	COG0322	excinuclease ABC activity
FDY98_RS21760	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FDY98_RS21765	COG0776	regulation of translation
FDY98_RS21775	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FDY98_RS21780	COG0284	orotidine-5'-phosphate decarboxylase activity
FDY98_RS21805	COG0372	Belongs to the citrate synthase family
FDY98_RS21810	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FDY98_RS21815	COG1802	Transcriptional regulator
FDY98_RS21820	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FDY98_RS21835	COG3118	belongs to the thioredoxin family
FDY98_RS21840	COG0628	permease
FDY98_RS21850	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FDY98_RS21875	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FDY98_RS21880	COG0512	Glutamine amidotransferase of anthranilate synthase
FDY98_RS21885	COG0803	Belongs to the bacterial solute-binding protein 9 family
FDY98_RS21890	COG0546	phosphoglycolate phosphatase activity
FDY98_RS21900	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FDY98_RS21930	COG0697	spore germination
FDY98_RS21940	COG0500	methyltransferase
FDY98_RS21945	COG4991	sh3 domain protein
FDY98_RS21965	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FDY98_RS21980	COG4575	ribosome binding
FDY98_RS22000	COG1063	alcohol dehydrogenase
FDY98_RS22005	COG1028	Short-chain dehydrogenase reductase Sdr
FDY98_RS22025	COG2081	HI0933 family
FDY98_RS22050	COG1177	transmembrane transport
FDY98_RS22080	COG3243	poly(R)-hydroxyalkanoic acid synthase
FDY98_RS22095	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FDY98_RS22125	COG4181	ATPase activity
FDY98_RS22255	COG1366	Belongs to the anti-sigma-factor antagonist family
FDY98_RS22275	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
FDY98_RS22295	COG0151	Belongs to the GarS family
FDY98_RS22300	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
FDY98_RS22310	COG0189	ligase activity
FDY98_RS22310	COG4067	protein conserved in archaea
FDY98_RS22315	COG2951	lytic endotransglycosylase activity
FDY98_RS22335	COG2212	antiporter activity
FDY98_RS22345	COG0651	ATP synthesis coupled electron transport
FDY98_RS22355	COG2111	Na H antiporter
FDY98_RS22360	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FDY98_RS22360	COG2111	Na H antiporter
FDY98_RS22390	COG0305	Participates in initiation and elongation during chromosome replication
FDY98_RS22405	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FDY98_RS22410	COG0360	Binds together with S18 to 16S ribosomal RNA
FDY98_RS22420	COG0557	exoribonuclease II activity
FDY98_RS22440	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FDY98_RS22450	COG0583	DNA-binding transcription factor activity
FDY98_RS22490	COG0446	pyridine nucleotide-disulphide oxidoreductase
FDY98_RS22490	COG1902	pentaerythritol trinitrate reductase activity
FDY98_RS22495	COG0697	spore germination
FDY98_RS22500	COG3153	acetyltransferase
FDY98_RS22500	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FDY98_RS22515	COG1115	amino acid carrier protein
FDY98_RS22550	COG3040	lipid binding
FDY98_RS22560	COG0473	3-isopropylmalate dehydrogenase activity
FDY98_RS22570	COG0655	NAD(P)H dehydrogenase (quinone) activity
FDY98_RS22580	COG2988	succinylglutamate desuccinylase activity
FDY98_RS22635	COG0129	dihydroxy-acid dehydratase activity
FDY98_RS22640	COG3657	addiction module killer protein
FDY98_RS22645	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FDY98_RS22650	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FDY98_RS22665	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FDY98_RS22680	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FDY98_RS22685	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FDY98_RS22700	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FDY98_RS22710	COG1278	Cold shock
FDY98_RS22725	COG2040	homocysteine
FDY98_RS22750	COG0583	DNA-binding transcription factor activity
FDY98_RS22770	COG0546	phosphoglycolate phosphatase activity
FDY98_RS22775	COG2271	Major facilitator Superfamily
FDY98_RS22785	COG2824	Alkylphosphonate utilization operon protein PhnA
FDY98_RS22820	COG1733	regulation of RNA biosynthetic process
FDY98_RS22845	COG0300	oxidoreductase activity
FDY98_RS22865	COG0640	Transcriptional regulator
FDY98_RS22900	COG0159	tryptophan synthase activity
FDY98_RS22920	COG2249	NAD(P)H dehydrogenase (quinone) activity
FDY98_RS22930	COG4115	mRNA cleavage
FDY98_RS22935	COG2226	methyltransferase
FDY98_RS22940	COG0583	DNA-binding transcription factor activity
FDY98_RS22945	COG0667	Aldo Keto reductase
FDY98_RS22985	COG0584	glycerophosphoryl diester phosphodiesterase
FDY98_RS22990	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FDY98_RS23035	COG4106	trans-aconitate 2-methyltransferase activity
FDY98_RS23065	COG2890	protein-(glutamine-N5) methyltransferase activity
FDY98_RS23070	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FDY98_RS23075	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FDY98_RS23085	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FDY98_RS23105	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FDY98_RS23110	COG0193	aminoacyl-tRNA hydrolase activity
FDY98_RS23115	COG0012	GTP binding
FDY98_RS23125	COG1362	aminopeptidase activity
FDY98_RS23130	COG0793	Belongs to the peptidase S41A family
FDY98_RS23135	COG0640	Transcriptional regulator
FDY98_RS23155	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FDY98_RS23160	COG1702	phosphate starvation-inducible protein PhoH
FDY98_RS23165	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FDY98_RS23170	COG4535	Mg2 and Co2 transporter CorC
FDY98_RS23175	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FDY98_RS23180	COG1064	alcohol dehydrogenase
FDY98_RS23185	COG2207	Transcriptional regulator
FDY98_RS23195	COG0583	DNA-binding transcription factor activity
FDY98_RS23200	COG3530	Putative quorum-sensing-regulated virulence factor
FDY98_RS23235	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FDY98_RS23240	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FDY98_RS23255	COG3938	Belongs to the proline racemase family
FDY98_RS23260	COG0604	alcohol dehydrogenase
FDY98_RS23260	COG1028	Short-chain dehydrogenase reductase Sdr
FDY98_RS23260	COG3321	synthase
FDY98_RS23270	COG0598	Magnesium transport protein CorA
FDY98_RS23380	COG0154	amidase activity
FDY98_RS23405	COG3706	GGDEF domain
FDY98_RS23410	COG0778	Nitroreductase
FDY98_RS23435	COG2910	NAD(P)H-binding
FDY98_RS23460	COG1288	antiporter activity
FDY98_RS23465	COG2235	arginine
FDY98_RS23480	COG3724	N-succinylarginine dihydrolase activity
FDY98_RS23485	COG1012	belongs to the aldehyde dehydrogenase family
FDY98_RS23500	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FDY98_RS23505	COG1028	Short-chain dehydrogenase reductase Sdr
FDY98_RS23520	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FDY98_RS23530	COG0386	Belongs to the glutathione peroxidase family
FDY98_RS23540	COG0217	transcriptional regulatory protein
FDY98_RS23560	COG0604	alcohol dehydrogenase
FDY98_RS23610	COG1879	ABC-type sugar transport system periplasmic component
FDY98_RS23620	COG1129	ABC transporter
FDY98_RS23630	COG1063	alcohol dehydrogenase
FDY98_RS23645	COG0698	ribose 5-phosphate isomerase
FDY98_RS23650	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FDY98_RS23665	COG0513	Belongs to the DEAD box helicase family
FDY98_RS23670	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FDY98_RS23700	COG1295	ribonuclease BN
FDY98_RS23710	COG0651	ATP synthesis coupled electron transport
FDY98_RS23715	COG1007	ATP synthesis coupled electron transport
FDY98_RS23735	COG1278	Cold shock
FDY98_RS23750	COG0583	DNA-binding transcription factor activity
FDY98_RS23755	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FDY98_RS23760	COG1012	belongs to the aldehyde dehydrogenase family
FDY98_RS23765	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FDY98_RS23780	COG0420	3'-5' exonuclease activity
FDY98_RS23785	COG0471	metal ion transport
FDY98_RS23800	COG1396	sequence-specific DNA binding
FDY98_RS23820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FDY98_RS23825	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FDY98_RS23835	COG1120	ATPase activity
FDY98_RS23860	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FDY98_RS23870	COG1802	Transcriptional regulator
FDY98_RS23890	COG0765	amino acid transport
FDY98_RS23905	COG4774	siderophore transport
FDY98_RS23920	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FDY98_RS23930	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FDY98_RS24080	COG1132	(ABC) transporter
FDY98_RS24085	COG1120	ATPase activity
FDY98_RS24090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FDY98_RS24100	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FDY98_RS24105	COG4771	TonB-dependent receptor
FDY98_RS24110	COG4771	TonB-dependent receptor
FDY98_RS24115	COG0583	DNA-binding transcription factor activity
FDY98_RS24125	COG2133	pyrroloquinoline quinone binding
FDY98_RS24130	COG4191	Histidine kinase
FDY98_RS24200	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FDY98_RS24210	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FDY98_RS24220	COG0583	DNA-binding transcription factor activity
FDY98_RS24225	COG1760	l-serine dehydratase
FDY98_RS24245	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FDY98_RS24250	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FDY98_RS24270	COG0617	tRNA 3'-terminal CCA addition
FDY98_RS24275	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FDY98_RS24295	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FDY98_RS24300	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FDY98_RS24305	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FDY98_RS24320	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FDY98_RS24330	COG1765	OsmC-like protein
FDY98_RS24335	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FDY98_RS24340	COG1560	Kdo2-lipid A biosynthetic process
FDY98_RS24345	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FDY98_RS24365	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FDY98_RS24380	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FDY98_RS24385	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FDY98_RS24390	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FDY98_RS24405	COG1737	Transcriptional regulator
FDY98_RS24420	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FDY98_RS24430	COG0589	response to stress
FDY98_RS24435	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FDY98_RS24440	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FDY98_RS24445	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FDY98_RS24450	COG0589	response to stress
FDY98_RS24465	COG0473	3-isopropylmalate dehydrogenase activity
FDY98_RS24470	COG2217	Heavy metal translocating P-type atpase
FDY98_RS24475	COG0789	Transcriptional regulator
FDY98_RS24485	COG1595	DNA-templated transcription, initiation
FDY98_RS24495	COG0450	alkyl hydroperoxide reductase
FDY98_RS24500	COG1253	flavin adenine dinucleotide binding
FDY98_RS24510	COG1854	S-ribosylhomocysteine lyase activity
FDY98_RS24525	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FDY98_RS24530	COG1012	belongs to the aldehyde dehydrogenase family
FDY98_RS24535	COG1522	sequence-specific DNA binding
FDY98_RS24540	COG3608	succinylglutamate desuccinylase aspartoacylase
FDY98_RS24550	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FDY98_RS24560	COG2431	L-lysine efflux transmembrane transporter activity
FDY98_RS24575	COG0252	asparaginase activity
FDY98_RS24580	COG1115	amino acid carrier protein
FDY98_RS24595	COG1944	ATP diphosphatase activity
FDY98_RS24645	COG2205	protein histidine kinase activity
FDY98_RS24650	COG0745	RESPONSE REGULATOR receiver
FDY98_RS24655	COG0745	RESPONSE REGULATOR receiver
FDY98_RS24660	COG2205	protein histidine kinase activity
FDY98_RS24725	COG2205	protein histidine kinase activity
FDY98_RS24725	COG0784	Response regulator, receiver
FDY98_RS24845	COG0697	spore germination
FDY98_RS24850	COG1192	Involved in chromosome partitioning
FDY98_RS24855	COG1475	DNA binding
FDY98_RS24870	COG4974	Belongs to the 'phage' integrase family
FDY98_RS25125	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FDY98_RS25130	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FDY98_RS25135	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FDY98_RS25215	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FDY98_RS25220	COG5642	Protein of unknown function (DUF2384)
FDY98_RS25225	COG5654	RES domain protein
FDY98_RS25230	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FDY98_RS25235	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FDY98_RS25265	COG1024	Enoyl-CoA hydratase
FDY98_RS25265	COG1250	3-hydroxyacyl-CoA dehydrogenase
FDY98_RS25280	COG1024	Enoyl-CoA hydratase
FDY98_RS25285	COG1250	3-hydroxyacyl-CoA dehydrogenase
FDY98_RS25290	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FDY98_RS25315	COG3181	Tripartite tricarboxylate transporter family receptor
FDY98_RS25350	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FDY98_RS25370	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
FDY98_RS25410	COG0444	Belongs to the ABC transporter superfamily
FDY98_RS25415	COG4172	Belongs to the ABC transporter superfamily
FDY98_RS25435	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FDY98_RS25440	COG0583	DNA-binding transcription factor activity
FDY98_RS25470	COG4172	Belongs to the ABC transporter superfamily
FDY98_RS25485	COG2608	mercury ion transmembrane transporter activity
FDY98_RS25595	COG0583	DNA-binding transcription factor activity
FDY98_RS25605	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
FDY98_RS25840	COG2974	May be involved in recombination