locus-tag	class	description
BV504_RS00050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BV504_RS00065	COG0189	ligase activity
BV504_RS00065	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BV504_RS00080	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BV504_RS00090	COG0425	Belongs to the sulfur carrier protein TusA family
BV504_RS00100	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BV504_RS00105	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BV504_RS00115	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BV504_RS00120	COG0745	RESPONSE REGULATOR receiver
BV504_RS00125	COG2826	transposase and inactivated derivatives, IS30 family
BV504_RS00135	COG2205	protein histidine kinase activity
BV504_RS00140	COG1720	tRNA m6t6A37 methyltransferase activity
BV504_RS00170	COG0563	adenylate kinase activity
BV504_RS00180	COG0742	ribosomal rna small subunit methyltransferase
BV504_RS00195	COG3091	SprT-like family
BV504_RS00200	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BV504_RS00210	COG0784	Response regulator, receiver
BV504_RS00210	COG2198	Histidine kinase
BV504_RS00210	COG2205	protein histidine kinase activity
BV504_RS00220	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BV504_RS00240	COG0037	tRNA processing
BV504_RS00245	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BV504_RS00275	COG0348	domain, Protein
BV504_RS00280	COG2010	Cytochrome c
BV504_RS00295	COG3278	Belongs to the heme-copper respiratory oxidase family
BV504_RS00330	COG3193	protein, possibly involved in utilization of glycolate and propanediol
BV504_RS00335	COG0247	lactate metabolic process
BV504_RS00340	COG0277	FAD linked oxidase domain protein
BV504_RS00345	COG0277	FAD linked oxidase domain protein
BV504_RS00350	COG2186	Transcriptional regulator
BV504_RS00360	COG1620	l-lactate permease
BV504_RS00380	COG2351	hydroxyisourate hydrolase activity
BV504_RS00395	COG0601	transmembrane transport
BV504_RS00400	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BV504_RS00410	COG0444	Belongs to the ABC transporter superfamily
BV504_RS00425	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BV504_RS00435	COG1953	Uracil, thiamine, allantoin
BV504_RS00470	COG0765	amino acid transport
BV504_RS00480	COG1288	antiporter activity
BV504_RS00485	COG0469	pyruvate kinase activity
BV504_RS00500	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BV504_RS00510	COG0697	spore germination
BV504_RS00550	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BV504_RS00560	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BV504_RS00560	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BV504_RS00595	COG0446	pyridine nucleotide-disulphide oxidoreductase
BV504_RS00625	COG0784	Response regulator, receiver
BV504_RS00625	COG2205	protein histidine kinase activity
BV504_RS00645	COG0659	secondary active sulfate transmembrane transporter activity
BV504_RS00650	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BV504_RS00690	COG0745	RESPONSE REGULATOR receiver
BV504_RS00695	COG2207	Transcriptional regulator
BV504_RS00705	COG0745	RESPONSE REGULATOR receiver
BV504_RS00710	COG2205	protein histidine kinase activity
BV504_RS00730	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BV504_RS00735	COG1309	transcriptional regulator
BV504_RS00740	COG1115	amino acid carrier protein
BV504_RS00745	COG0252	asparaginase activity
BV504_RS00750	COG1309	transcriptional regulator
BV504_RS00755	COG1028	Short-chain dehydrogenase reductase Sdr
BV504_RS00765	COG1570	exodeoxyribonuclease VII activity
BV504_RS00775	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BV504_RS00775	COG0519	Catalyzes the synthesis of GMP from XMP
BV504_RS00780	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BV504_RS00785	COG0732	type I restriction modification DNA specificity domain
BV504_RS00800	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BV504_RS00815	COG1917	Cupin 2, conserved barrel domain protein
BV504_RS00820	COG0456	acetyltransferase
BV504_RS00825	COG0583	DNA-binding transcription factor activity
BV504_RS00855	COG2814	Major facilitator Superfamily
BV504_RS00905	COG2814	Major facilitator Superfamily
BV504_RS00915	COG0640	Transcriptional regulator
BV504_RS00925	COG1854	S-ribosylhomocysteine lyase activity
BV504_RS00935	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BV504_RS00940	COG0798	PFAM Bile acid sodium symporter
BV504_RS00950	COG0215	cysteine-tRNA ligase activity
BV504_RS00955	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BV504_RS00980	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BV504_RS01015	COG4771	TonB-dependent receptor
BV504_RS01020	COG1429	ligase activity, forming nitrogen-metal bonds
BV504_RS01035	COG2814	Major facilitator Superfamily
BV504_RS01045	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
BV504_RS01050	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BV504_RS01055	COG5002	protein histidine kinase activity
BV504_RS01060	COG0745	RESPONSE REGULATOR receiver
BV504_RS01085	COG0583	DNA-binding transcription factor activity
BV504_RS01090	COG1335	isochorismatase
BV504_RS01105	COG1741	Belongs to the pirin family
BV504_RS01170	COG2274	protein secretion by the type I secretion system
BV504_RS01200	COG2226	methyltransferase
BV504_RS01215	COG4221	oxidoreductase activity
BV504_RS01220	COG2207	Transcriptional regulator
BV504_RS01225	COG1278	Cold shock
BV504_RS01230	COG4772	TonB-dependent receptor
BV504_RS01240	COG2130	NADP-dependent
BV504_RS01245	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BV504_RS01265	COG0583	DNA-binding transcription factor activity
BV504_RS01290	COG0254	rRNA binding
BV504_RS01295	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BV504_RS01300	COG1120	ATPase activity
BV504_RS01305	COG0483	inositol monophosphate 1-phosphatase activity
BV504_RS01320	COG1595	DNA-templated transcription, initiation
BV504_RS01350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BV504_RS01360	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BV504_RS01370	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BV504_RS01380	COG0657	acetylesterase activity
BV504_RS01410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BV504_RS01420	COG4615	Cyclic peptide transporter
BV504_RS01430	COG4771	TonB-dependent receptor
BV504_RS01435	COG0500	methyltransferase
BV504_RS01445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BV504_RS01450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BV504_RS01460	COG1132	(ABC) transporter
BV504_RS01465	COG1132	(ABC) transporter
BV504_RS01480	COG1609	Transcriptional regulator
BV504_RS01480	COG2207	Transcriptional regulator
BV504_RS01505	COG4774	siderophore transport
BV504_RS01515	COG1595	DNA-templated transcription, initiation
BV504_RS01520	COG3712	iron ion homeostasis
BV504_RS01540	COG1595	DNA-templated transcription, initiation
BV504_RS01550	COG4772	TonB-dependent receptor
BV504_RS01565	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
BV504_RS01585	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BV504_RS01590	COG0028	Belongs to the TPP enzyme family
BV504_RS01605	COG2133	pyrroloquinoline quinone binding
BV504_RS01610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BV504_RS01630	COG3501	Rhs element vgr protein
BV504_RS01720	COG2146	nitrite reductase [NAD(P)H] activity
BV504_RS01720	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BV504_RS01725	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BV504_RS01730	COG0243	molybdopterin cofactor binding
BV504_RS01735	COG1648	precorrin-2 dehydrogenase activity
BV504_RS01735	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BV504_RS01755	COG4948	Mandelate Racemase Muconate Lactonizing
BV504_RS01765	COG1012	belongs to the aldehyde dehydrogenase family
BV504_RS01770	COG2610	gluconate transmembrane transporter activity
BV504_RS01800	COG3181	Tripartite tricarboxylate transporter family receptor
BV504_RS01805	COG2059	Chromate
BV504_RS01810	COG2059	Chromate
BV504_RS01815	COG1802	Transcriptional regulator
BV504_RS01830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BV504_RS01840	COG3707	response regulator
BV504_RS01845	COG2223	nitrite transmembrane transporter activity
BV504_RS01860	COG2989	Protein conserved in bacteria
BV504_RS01865	COG0739	heme binding
BV504_RS01870	COG0583	DNA-binding transcription factor activity
BV504_RS01875	COG0435	Glutathione S-transferase
BV504_RS01885	COG3237	CsbD-like
BV504_RS01900	COG1515	deoxyribonuclease V activity
BV504_RS01905	COG0519	Catalyzes the synthesis of GMP from XMP
BV504_RS01905	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BV504_RS01915	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BV504_RS01925	COG0668	transmembrane transport
BV504_RS01935	COG0484	heat shock protein binding
BV504_RS01945	COG0516	GMP reductase activity
BV504_RS01945	COG0517	IMP dehydrogenase activity
BV504_RS01955	COG0673	inositol 2-dehydrogenase activity
BV504_RS01960	COG1653	transport
BV504_RS01965	COG1609	Transcriptional regulator
BV504_RS01975	COG0813	purine-nucleoside phosphorylase activity
BV504_RS01980	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BV504_RS01985	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BV504_RS01995	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BV504_RS02005	COG1349	DNA-binding transcription factor activity
BV504_RS02010	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BV504_RS02015	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BV504_RS02020	COG1845	cytochrome c oxidase, subunit III
BV504_RS02025	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BV504_RS02030	COG0109	protoheme IX farnesyltransferase activity
BV504_RS02035	COG0505	Belongs to the CarA family
BV504_RS02050	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BV504_RS02055	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BV504_RS02060	COG0857	belongs to the CobB CobQ family
BV504_RS02060	COG0280	phosphate acetyltransferase
BV504_RS02065	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BV504_RS02080	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BV504_RS02095	COG1566	PFAM secretion protein HlyD family protein
BV504_RS02115	COG2826	transposase and inactivated derivatives, IS30 family
BV504_RS02120	COG1288	antiporter activity
BV504_RS02130	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BV504_RS02140	COG0786	glutamate:sodium symporter activity
BV504_RS02145	COG1063	alcohol dehydrogenase
BV504_RS02160	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BV504_RS02210	COG0697	spore germination
BV504_RS02220	COG0656	L-ascorbic acid biosynthetic process
BV504_RS02235	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BV504_RS02240	COG0583	DNA-binding transcription factor activity
BV504_RS02255	COG0789	Transcriptional regulator
BV504_RS02295	COG1757	Na H antiporter
BV504_RS02320	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BV504_RS02325	COG3938	Belongs to the proline racemase family
BV504_RS02335	COG1120	ATPase activity
BV504_RS02345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BV504_RS02350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BV504_RS02355	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BV504_RS02360	COG1522	sequence-specific DNA binding
BV504_RS02365	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BV504_RS02370	COG2072	flavoprotein involved in K transport
BV504_RS02395	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BV504_RS02410	COG1396	sequence-specific DNA binding
BV504_RS02415	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
BV504_RS02425	COG3459	Glycosyltransferase 36 associated
BV504_RS02430	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BV504_RS02435	COG0471	metal ion transport
BV504_RS02440	COG0420	3'-5' exonuclease activity
BV504_RS02445	COG0419	ATPase involved in DNA repair
BV504_RS02455	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BV504_RS02460	COG1012	belongs to the aldehyde dehydrogenase family
BV504_RS02465	COG1454	alcohol dehydrogenase
BV504_RS02470	COG0659	secondary active sulfate transmembrane transporter activity
BV504_RS02480	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BV504_RS02485	COG0583	DNA-binding transcription factor activity
BV504_RS02500	COG1278	Cold shock
BV504_RS02505	COG0471	metal ion transport
BV504_RS02505	COG3273	potassium ion transport
BV504_RS02520	COG0651	ATP synthesis coupled electron transport
BV504_RS02525	COG0651	ATP synthesis coupled electron transport
BV504_RS02530	COG2111	Na H antiporter
BV504_RS02530	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BV504_RS02535	COG1295	ribonuclease BN
BV504_RS02540	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BV504_RS02565	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BV504_RS02570	COG0513	Belongs to the DEAD box helicase family
BV504_RS02580	COG3180	Ammonia monooxygenase
BV504_RS02585	COG1132	(ABC) transporter
BV504_RS02590	COG0604	alcohol dehydrogenase
BV504_RS02595	COG0494	nUDIX hydrolase
BV504_RS02615	COG0217	transcriptional regulatory protein
BV504_RS02620	COG1280	lysine exporter protein (LysE YggA)
BV504_RS02625	COG0386	Belongs to the glutathione peroxidase family
BV504_RS02635	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BV504_RS02650	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BV504_RS02660	COG3138	arginine N-succinyltransferase
BV504_RS02665	COG1012	belongs to the aldehyde dehydrogenase family
BV504_RS02670	COG3724	N-succinylarginine dihydrolase activity
BV504_RS02675	COG1683	Conserved Protein
BV504_RS02685	COG1846	Transcriptional regulator
BV504_RS02695	COG0384	phenazine biosynthesis protein PhzF
BV504_RS02705	COG0583	DNA-binding transcription factor activity
BV504_RS02715	COG1733	regulation of RNA biosynthetic process
BV504_RS02720	COG2910	NAD(P)H-binding
BV504_RS02730	COG0778	Nitroreductase
BV504_RS02745	COG5654	RES domain protein
BV504_RS02750	COG5642	Protein of unknown function (DUF2384)
BV504_RS02760	COG0154	amidase activity
BV504_RS02785	COG0477	Major facilitator Superfamily
BV504_RS02790	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BV504_RS02795	COG1595	DNA-templated transcription, initiation
BV504_RS02810	COG1183	phosphatidylcholine synthase activity
BV504_RS02825	COG0438	transferase activity, transferring glycosyl groups
BV504_RS02840	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BV504_RS02855	COG2943	transferase activity, transferring hexosyl groups
BV504_RS02860	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
BV504_RS02910	COG1960	acyl-CoA dehydrogenase activity
BV504_RS02920	COG0318	PFAM AMP-dependent synthetase and ligase
BV504_RS02925	COG1250	3-hydroxyacyl-CoA dehydrogenase
BV504_RS02930	COG1024	Enoyl-CoA hydratase
BV504_RS02935	COG0625	glutathione transferase activity
BV504_RS02950	COG0625	glutathione transferase activity
BV504_RS02955	COG1794	racemase activity, acting on amino acids and derivatives
BV504_RS02960	COG1764	response to oxidative stress
BV504_RS02965	COG1846	Transcriptional regulator
BV504_RS02970	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BV504_RS02980	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BV504_RS02985	COG3265	gluconokinase activity
BV504_RS02990	COG1609	Transcriptional regulator
BV504_RS03005	COG1764	response to oxidative stress
BV504_RS03020	COG4566	intracellular signal transduction
BV504_RS03025	COG4191	Histidine kinase
BV504_RS03055	COG1653	transport
BV504_RS03060	COG1175	transmembrane transport
BV504_RS03070	COG3842	ATPase activity
BV504_RS03085	COG1072	(Pantothenic acid kinase))
BV504_RS03095	COG1070	Carbohydrate kinase
BV504_RS03100	COG1538	Outer membrane efflux protein
BV504_RS03105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BV504_RS03140	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BV504_RS03155	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BV504_RS03175	COG2009	succinate dehydrogenase
BV504_RS03180	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BV504_RS03185	COG1053	succinate dehydrogenase
BV504_RS03225	COG2188	Transcriptional regulator
BV504_RS03230	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BV504_RS03240	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BV504_RS03240	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BV504_RS03280	COG1175	transmembrane transport
BV504_RS03285	COG0395	ABC-type sugar transport system, permease component
BV504_RS03290	COG3842	ATPase activity
BV504_RS03295	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BV504_RS03300	COG3119	arylsulfatase activity
BV504_RS03305	COG0583	DNA-binding transcription factor activity
BV504_RS03310	COG3768	UPF0283 membrane protein
BV504_RS03315	COG3106	COG3106 Predicted ATPase
BV504_RS03325	COG0676	glucose-6-phosphate 1-epimerase activity
BV504_RS03340	COG0791	NLP P60 protein
BV504_RS03345	COG2814	Major facilitator Superfamily
BV504_RS03350	COG1124	(ABC) transporter
BV504_RS03355	COG1136	(ABC) transporter
BV504_RS03355	COG0577	efflux transmembrane transporter activity
BV504_RS03360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BV504_RS03365	COG0601	transmembrane transport
BV504_RS03370	COG0747	negative chemotaxis
BV504_RS03390	COG3133	Outer membrane lipoprotein
BV504_RS03405	COG2850	peptidyl-arginine hydroxylation
BV504_RS03415	COG2915	High frequency lysogenization protein hflD homolog
BV504_RS03420	COG0482	sulfurtransferase activity
BV504_RS03430	COG1187	pseudouridine synthase activity
BV504_RS03445	COG0542	response to heat
BV504_RS03450	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BV504_RS03455	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BV504_RS03460	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BV504_RS03465	COG1674	ftsk spoiiie
BV504_RS03470	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BV504_RS03475	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BV504_RS03485	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BV504_RS03490	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BV504_RS03495	COG2902	Dehydrogenase
BV504_RS03500	COG0167	dihydroorotate dehydrogenase activity
BV504_RS03505	COG3130	regulation of translation
BV504_RS03510	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BV504_RS03510	COG0116	Belongs to the methyltransferase superfamily
BV504_RS03525	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BV504_RS03535	COG5001	Diguanylate cyclase
BV504_RS03535	COG3706	GGDEF domain
BV504_RS03535	COG2203	Gaf domain
BV504_RS03535	COG4251	negative regulation of phosphorylation
BV504_RS03540	COG0501	Belongs to the peptidase M48B family
BV504_RS03545	COG0436	Aminotransferase
BV504_RS03555	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BV504_RS03565	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BV504_RS03575	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BV504_RS03610	COG1131	(ABC) transporter
BV504_RS03615	COG0842	Transport permease protein
BV504_RS03620	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BV504_RS03620	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BV504_RS03640	COG0702	epimerase
BV504_RS03645	COG1090	epimerase
BV504_RS03685	COG0583	DNA-binding transcription factor activity
BV504_RS03710	COG0477	Major facilitator Superfamily
BV504_RS03715	COG0733	neurotransmitter:sodium symporter activity
BV504_RS03720	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BV504_RS03725	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BV504_RS03745	COG2840	Smr protein MutS2
BV504_RS03755	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BV504_RS03770	COG3243	poly(R)-hydroxyalkanoic acid synthase
BV504_RS03775	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BV504_RS03785	COG4535	Mg2 and Co2 transporter CorC
BV504_RS03790	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BV504_RS03795	COG1702	phosphate starvation-inducible protein PhoH
BV504_RS03800	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BV504_RS03820	COG0640	Transcriptional regulator
BV504_RS03830	COG1362	aminopeptidase activity
BV504_RS03840	COG0012	GTP binding
BV504_RS03845	COG0193	aminoacyl-tRNA hydrolase activity
BV504_RS03850	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BV504_RS03855	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BV504_RS03865	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BV504_RS03870	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BV504_RS03880	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BV504_RS03885	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BV504_RS03890	COG2890	protein-(glutamine-N5) methyltransferase activity
BV504_RS03900	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BV504_RS03920	COG3842	ATPase activity
BV504_RS03925	COG1176	ABC-type spermidine putrescine transport system, permease component I
BV504_RS03930	COG1177	transmembrane transport
BV504_RS03945	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BV504_RS03955	COG2081	HI0933 family
BV504_RS03970	COG4575	ribosome binding
BV504_RS03980	COG3264	Mechanosensitive ion channel
BV504_RS03980	COG1196	nuclear chromosome segregation
BV504_RS03985	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BV504_RS04005	COG4991	sh3 domain protein
BV504_RS04010	COG0500	methyltransferase
BV504_RS04030	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BV504_RS04035	COG4208	sulfate ABC transporter
BV504_RS04050	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BV504_RS04055	COG1252	NADH dehydrogenase
BV504_RS04060	COG0546	phosphoglycolate phosphatase activity
BV504_RS04070	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BV504_RS04080	COG0039	L-malate dehydrogenase activity
BV504_RS04120	COG0730	response to heat
BV504_RS04125	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BV504_RS04140	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
BV504_RS04170	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BV504_RS04175	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BV504_RS04180	COG3307	-O-antigen
BV504_RS04205	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BV504_RS04215	COG1088	dTDP-glucose 4,6-dehydratase activity
BV504_RS04230	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BV504_RS04270	COG2826	transposase and inactivated derivatives, IS30 family
BV504_RS04285	COG2826	transposase and inactivated derivatives, IS30 family
BV504_RS04290	COG1181	Belongs to the D-alanine--D-alanine ligase family
BV504_RS04295	COG1254	Belongs to the acylphosphatase family
BV504_RS04300	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BV504_RS04300	COG0189	ligase activity
BV504_RS04335	COG0463	Glycosyl transferase, family 2
BV504_RS04340	COG0438	transferase activity, transferring glycosyl groups
BV504_RS04350	COG0438	transferase activity, transferring glycosyl groups
BV504_RS04350	COG1216	Glycosyl transferase, family 2
BV504_RS04395	COG0033	Phosphoglucomutase
BV504_RS04400	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BV504_RS04435	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BV504_RS04440	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BV504_RS04450	COG0156	8-amino-7-oxononanoate synthase activity
BV504_RS04455	COG0604	alcohol dehydrogenase
BV504_RS04455	COG1028	Short-chain dehydrogenase reductase Sdr
BV504_RS04455	COG3321	synthase
BV504_RS04460	COG1368	sulfuric ester hydrolase activity
BV504_RS04480	COG5001	Diguanylate cyclase
BV504_RS04480	COG3300	MHYT domain
BV504_RS04495	COG2153	protein acetylation
BV504_RS04540	COG0318	PFAM AMP-dependent synthetase and ligase
BV504_RS04560	COG2056	Na+-H+ antiporter family
BV504_RS04565	COG2986	histidine ammonia-lyase
BV504_RS04575	COG0010	Belongs to the arginase family
BV504_RS04580	COG1228	amidohydrolase
BV504_RS04585	COG3314	Sporulation integral membrane protein YlbJ
BV504_RS04615	COG3246	L-lysine catabolic process to acetate
BV504_RS04625	COG1802	Transcriptional regulator
BV504_RS04630	COG4948	Mandelate Racemase Muconate Lactonizing
BV504_RS04635	COG1063	alcohol dehydrogenase
BV504_RS04640	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BV504_RS04645	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BV504_RS04650	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BV504_RS04655	COG0246	Mannitol dehydrogenase
BV504_RS04660	COG1312	Catalyzes the dehydration of D-mannonate
BV504_RS04665	COG4145	pantothenate transmembrane transporter activity
BV504_RS04675	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BV504_RS04680	COG1737	Transcriptional regulator
BV504_RS04690	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BV504_RS04695	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BV504_RS04700	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BV504_RS04705	COG1609	Transcriptional regulator
BV504_RS04710	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BV504_RS04715	COG2813	Specifically methylates the guanine in position
BV504_RS04720	COG2186	Transcriptional regulator
BV504_RS04725	COG1028	Short-chain dehydrogenase reductase Sdr
BV504_RS04735	COG1063	alcohol dehydrogenase
BV504_RS04740	COG2721	sulfolactate sulfo-lyase activity
BV504_RS04745	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BV504_RS04765	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BV504_RS04775	COG0494	nUDIX hydrolase
BV504_RS04780	COG3151	Protein conserved in bacteria
BV504_RS04785	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BV504_RS04790	COG0175	sulfate reduction
BV504_RS04795	COG2895	sulfate adenylyltransferase (ATP) activity
BV504_RS04800	COG1410	methionine synthase
BV504_RS04800	COG0646	methionine synthase
BV504_RS04805	COG0747	negative chemotaxis
BV504_RS04815	COG1126	abc transporter atp-binding protein
BV504_RS04830	COG2738	Putative neutral zinc metallopeptidase
BV504_RS04840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BV504_RS04845	COG1120	ATPase activity
BV504_RS04850	COG0500	methyltransferase
BV504_RS04855	COG4106	trans-aconitate 2-methyltransferase activity
BV504_RS04860	COG0166	Belongs to the GPI family
BV504_RS04875	COG0560	Phosphoserine phosphatase
BV504_RS04900	COG1509	lysine 2,3-aminomutase activity
BV504_RS04905	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BV504_RS04910	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
BV504_RS04915	COG0688	phosphatidylethanolamine metabolic process
BV504_RS04925	COG1162	GTPase activity
BV504_RS04940	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BV504_RS04940	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BV504_RS04945	COG0802	atpase or kinase
BV504_RS04950	COG0860	N-Acetylmuramoyl-L-alanine amidase
BV504_RS04955	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BV504_RS04960	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BV504_RS04965	COG1923	regulation of RNA biosynthetic process
BV504_RS04970	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BV504_RS04975	COG0330	HflC and HflK could
BV504_RS04980	COG0330	HflC and HflK could
BV504_RS04985	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BV504_RS04990	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BV504_RS04995	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
BV504_RS05000	COG1666	GTP binding
BV504_RS05005	COG0308	aminopeptidase N
BV504_RS05010	COG1597	lipid kinase activity
BV504_RS05025	COG0741	lytic transglycosylase activity
BV504_RS05035	COG0326	Molecular chaperone. Has ATPase activity
BV504_RS05040	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BV504_RS05045	COG2062	phosphohistidine phosphatase, SixA
BV504_RS05050	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BV504_RS05055	COG0154	amidase activity
BV504_RS05060	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BV504_RS05065	COG1077	Cell shape determining protein MreB Mrl
BV504_RS05070	COG1792	Involved in formation and maintenance of cell shape
BV504_RS05075	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BV504_RS05080	COG0424	maF-like protein
BV504_RS05095	COG0312	modulator of DNA gyrase
BV504_RS05100	COG3028	Belongs to the UPF0307 family
BV504_RS05105	COG0312	modulator of DNA gyrase
BV504_RS05110	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BV504_RS05115	COG1660	Displays ATPase and GTPase activities
BV504_RS05135	COG1137	ATPase activity
BV504_RS05150	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BV504_RS05160	COG1127	ABC transporter
BV504_RS05165	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BV504_RS05170	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BV504_RS05185	COG5007	Belongs to the BolA IbaG family
BV504_RS05190	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BV504_RS05195	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BV504_RS05200	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BV504_RS05205	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BV504_RS05220	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BV504_RS05225	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BV504_RS05230	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BV504_RS05235	COG0723	plastoquinol--plastocyanin reductase activity
BV504_RS05240	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BV504_RS05245	COG2857	Cytochrome c1
BV504_RS05250	COG0625	glutathione transferase activity
BV504_RS05255	COG2969	positive regulation of protein catabolic process
BV504_RS05260	COG2823	Periplasmic or secreted lipoprotein
BV504_RS05265	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BV504_RS05270	COG0792	nuclease activity
BV504_RS05290	COG0275	rRNA processing
BV504_RS05295	COG3116	cell division
BV504_RS05305	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BV504_RS05310	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BV504_RS05315	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BV504_RS05320	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BV504_RS05330	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BV504_RS05335	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BV504_RS05340	COG1181	Belongs to the D-alanine--D-alanine ligase family
BV504_RS05360	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BV504_RS05375	COG0653	protein targeting
BV504_RS05385	COG0352	thiamine-phosphate diphosphorylase activity
BV504_RS05390	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BV504_RS05395	COG2957	Belongs to the agmatine deiminase family
BV504_RS05405	COG1136	(ABC) transporter
BV504_RS05420	COG1132	(ABC) transporter
BV504_RS05425	COG1663	tetraacyldisaccharide 4'-kinase activity
BV504_RS05430	COG2835	tetraacyldisaccharide 4'-kinase activity
BV504_RS05435	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BV504_RS05440	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BV504_RS05445	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BV504_RS05450	COG1530	ribonuclease E activity
BV504_RS05460	COG0546	phosphoglycolate phosphatase activity
BV504_RS05470	COG0424	maF-like protein
BV504_RS05475	COG1399	metal-binding, possibly nucleic acid-binding protein
BV504_RS05480	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BV504_RS05485	COG0416	fatty acid biosynthetic process
BV504_RS05500	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BV504_RS05505	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BV504_RS05510	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BV504_RS05515	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BV504_RS05520	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BV504_RS05535	COG0084	hydrolase, TatD family'
BV504_RS05565	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BV504_RS05575	COG1780	Probably involved in ribonucleotide reductase function
BV504_RS05580	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BV504_RS05600	COG0811	peptide transport
BV504_RS05605	COG0811	peptide transport
BV504_RS05610	COG0848	biopolymer transport protein
BV504_RS05625	COG0708	Exodeoxyribonuclease III
BV504_RS05640	COG1199	ATP-dependent helicase activity
BV504_RS05645	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BV504_RS05670	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BV504_RS05675	COG0481	GTPase activity
BV504_RS05680	COG0681	Belongs to the peptidase S26 family
BV504_RS05685	COG0571	ribonuclease III activity
BV504_RS05700	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BV504_RS05710	COG2205	protein histidine kinase activity
BV504_RS05710	COG5002	protein histidine kinase activity
BV504_RS05710	COG0784	Response regulator, receiver
BV504_RS05720	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BV504_RS05725	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BV504_RS05730	COG3956	TIGRFAM MazG family protein
BV504_RS05735	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BV504_RS05780	COG2226	methyltransferase
BV504_RS05785	COG0318	PFAM AMP-dependent synthetase and ligase
BV504_RS05800	COG1024	Enoyl-CoA hydratase
BV504_RS05805	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BV504_RS05810	COG1960	acyl-CoA dehydrogenase activity
BV504_RS05850	COG1960	acyl-CoA dehydrogenase activity
BV504_RS05855	COG1250	3-hydroxyacyl-CoA dehydrogenase
BV504_RS05855	COG1024	Enoyl-CoA hydratase
BV504_RS05865	COG0625	glutathione transferase activity
BV504_RS05915	COG0583	DNA-binding transcription factor activity
BV504_RS05925	COG2423	ornithine cyclodeaminase activity
BV504_RS05930	COG2031	fatty acid transporter
BV504_RS05940	COG0662	Cupin 2, conserved barrel domain protein
BV504_RS05940	COG2207	Transcriptional regulator
BV504_RS06010	COG1028	Short-chain dehydrogenase reductase Sdr
BV504_RS06025	COG0579	oxidoreductase
BV504_RS06035	COG1280	lysine exporter protein (LysE YggA)
BV504_RS06055	COG4122	O-methyltransferase activity
BV504_RS06070	COG1704	LemA family
BV504_RS06075	COG0501	Belongs to the peptidase M48B family
BV504_RS06080	COG1073	alpha beta
BV504_RS06090	COG3483	tryptophan 2,3-dioxygenase activity
BV504_RS06100	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BV504_RS06100	COG0456	acetyltransferase
BV504_RS06105	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BV504_RS06110	COG0583	DNA-binding transcription factor activity
BV504_RS06125	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BV504_RS06130	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BV504_RS06140	COG0653	protein targeting
BV504_RS06145	COG2211	Major facilitator Superfamily
BV504_RS06150	COG1047	Peptidyl-prolyl cis-trans
BV504_RS06160	COG2199	diguanylate cyclase activity
BV504_RS06175	COG0442	prolyl-tRNA aminoacylation
BV504_RS06185	COG3135	benzoate transporter
BV504_RS06190	COG1396	sequence-specific DNA binding
BV504_RS06200	COG0584	glycerophosphoryl diester phosphodiesterase
BV504_RS06210	COG1737	Transcriptional regulator
BV504_RS06215	COG1024	Enoyl-CoA hydratase
BV504_RS06225	COG1024	Enoyl-CoA hydratase
BV504_RS06230	COG3273	potassium ion transport
BV504_RS06230	COG0471	metal ion transport
BV504_RS06235	COG1349	DNA-binding transcription factor activity
BV504_RS06240	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BV504_RS06250	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BV504_RS06265	COG0395	ABC-type sugar transport system, permease component
BV504_RS06275	COG3842	ATPase activity
BV504_RS06280	COG3842	ATPase activity
BV504_RS06460	COG3706	GGDEF domain
BV504_RS06465	COG3706	GGDEF domain
BV504_RS06490	COG1321	iron dependent repressor
BV504_RS06500	COG1121	(ABC) transporter
BV504_RS06505	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BV504_RS06525	COG2610	gluconate transmembrane transporter activity
BV504_RS06530	COG2056	Na+-H+ antiporter family
BV504_RS06540	COG0459	protein refolding
BV504_RS06545	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BV504_RS06555	COG1028	Short-chain dehydrogenase reductase Sdr
BV504_RS06585	COG0302	gtp cyclohydrolase
BV504_RS06600	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BV504_RS06610	COG2264	protein methyltransferase activity
BV504_RS06620	COG0511	ligase activity, forming carbon-carbon bonds
BV504_RS06630	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BV504_RS06635	COG0515	serine threonine protein kinase
BV504_RS06635	COG2815	serine threonine protein kinase
BV504_RS06640	COG0205	6-phosphofructokinase activity
BV504_RS06645	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BV504_RS06650	COG0137	argininosuccinate synthase activity
BV504_RS06665	COG5002	protein histidine kinase activity
BV504_RS06675	COG2176	DNA-directed DNA polymerase activity
BV504_RS06675	COG5002	protein histidine kinase activity
BV504_RS06690	COG1966	Carbon starvation protein
BV504_RS06700	COG0003	Pfam Anion-transporting ATPase
BV504_RS06715	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BV504_RS06720	COG4660	Part of a membrane complex involved in electron transport
BV504_RS06725	COG4659	FMN binding
BV504_RS06730	COG4658	electron transport chain
BV504_RS06740	COG2878	Part of a membrane complex involved in electron transport
BV504_RS06745	COG4657	Part of a membrane complex involved in electron transport
BV504_RS06750	COG1283	sodium-dependent phosphate transmembrane transporter activity
BV504_RS06760	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BV504_RS06765	COG5001	Diguanylate cyclase
BV504_RS06765	COG3300	MHYT domain
BV504_RS06770	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BV504_RS06770	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BV504_RS06790	COG0824	Thioesterase
BV504_RS06800	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BV504_RS06805	COG1605	Chorismate mutase
BV504_RS06805	COG0077	Prephenate dehydratase
BV504_RS06810	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BV504_RS06850	COG0237	dephospho-CoA kinase activity
BV504_RS06855	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BV504_RS06910	COG1611	Belongs to the LOG family
BV504_RS06915	COG0583	DNA-binding transcription factor activity
BV504_RS06925	COG0509	glycine decarboxylation via glycine cleavage system
BV504_RS06935	COG1115	amino acid carrier protein
BV504_RS06945	COG4942	peptidase
BV504_RS06955	COG0583	DNA-binding transcription factor activity
BV504_RS06960	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BV504_RS06985	COG1028	Short-chain dehydrogenase reductase Sdr
BV504_RS06990	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BV504_RS06995	COG2205	protein histidine kinase activity
BV504_RS07005	COG0418	dihydroorotase activity
BV504_RS07010	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BV504_RS07015	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BV504_RS07050	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BV504_RS07055	COG0084	hydrolase, TatD family'
BV504_RS07060	COG0354	folic acid binding
BV504_RS07075	COG0556	nucleotide-excision repair
BV504_RS07090	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BV504_RS07095	COG0583	DNA-binding transcription factor activity
BV504_RS07100	COG1056	cytidyltransferase-related domain
BV504_RS07100	COG1051	belongs to the nudix hydrolase family
BV504_RS07105	COG1295	ribonuclease BN
BV504_RS07110	COG1254	Belongs to the acylphosphatase family
BV504_RS07115	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BV504_RS07125	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BV504_RS07130	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BV504_RS07135	COG0632	four-way junction helicase activity
BV504_RS07140	COG2255	four-way junction helicase activity
BV504_RS07145	COG0824	Thioesterase
BV504_RS07165	COG0823	Involved in the tonB-independent uptake of proteins
BV504_RS07170	COG2885	chlorophyll binding
BV504_RS07180	COG1028	Short-chain dehydrogenase reductase Sdr
BV504_RS07190	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BV504_RS07205	COG0729	surface antigen
BV504_RS07210	COG2911	Protein conserved in bacteria
BV504_RS07215	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BV504_RS07225	COG0288	reversible hydration of carbon dioxide
BV504_RS07235	COG0456	acetyltransferase
BV504_RS07240	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BV504_RS07245	COG1917	Cupin 2, conserved barrel domain protein
BV504_RS07255	COG0583	DNA-binding transcription factor activity
BV504_RS07260	COG0625	glutathione transferase activity
BV504_RS07265	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BV504_RS07265	COG1017	nitric oxide dioxygenase activity
BV504_RS07280	COG4067	protein conserved in archaea
BV504_RS07280	COG0189	ligase activity
BV504_RS07295	COG0735	belongs to the Fur family
BV504_RS07300	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BV504_RS07305	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BV504_RS07310	COG2166	iron-sulfur cluster assembly
BV504_RS07325	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BV504_RS07325	COG0316	Belongs to the HesB IscA family
BV504_RS07335	COG0534	Mate efflux family protein
BV504_RS07340	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BV504_RS07350	COG2840	Smr protein MutS2
BV504_RS07375	COG0259	pyridoxamine-phosphate oxidase activity
BV504_RS07385	COG0123	including yeast histone deacetylase and acetoin utilization protein
BV504_RS07395	COG2920	part of a sulfur-relay system
BV504_RS07405	COG2923	Belongs to the DsrF TusC family
BV504_RS07420	COG0667	Aldo Keto reductase
BV504_RS07425	COG0582	viral genome integration into host DNA
BV504_RS07440	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BV504_RS07470	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BV504_RS07480	COG3311	Transcriptional regulator
BV504_RS07495	COG4983	Phage plasmid primase, P4 family domain protein
BV504_RS07540	COG2003	Belongs to the UPF0758 family
BV504_RS07545	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BV504_RS07575	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BV504_RS07585	COG0596	Alpha beta hydrolase
BV504_RS07590	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BV504_RS07600	COG0640	Transcriptional regulator
BV504_RS07605	COG0616	signal peptide processing
BV504_RS07615	COG2816	NAD+ diphosphatase activity
BV504_RS07620	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BV504_RS07625	COG0328	RNA-DNA hybrid ribonuclease activity
BV504_RS07635	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BV504_RS07640	COG0741	lytic transglycosylase activity
BV504_RS07640	COG1388	LysM domain
BV504_RS07645	COG4166	transmembrane transport
BV504_RS07650	COG4174	ABC transporter (Permease)
BV504_RS07655	COG4239	(ABC) transporter, permease
BV504_RS07660	COG4172	Belongs to the ABC transporter superfamily
BV504_RS07675	COG2962	Rard protein
BV504_RS07685	COG0659	secondary active sulfate transmembrane transporter activity
BV504_RS07700	COG0318	PFAM AMP-dependent synthetase and ligase
BV504_RS07715	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BV504_RS07735	COG0515	serine threonine protein kinase
BV504_RS07745	COG0022	dehydrogenase e1 component
BV504_RS07750	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BV504_RS07755	COG1174	glycine betaine transport
BV504_RS07760	COG1125	glycine betaine transport
BV504_RS07765	COG1174	glycine betaine transport
BV504_RS07770	COG1732	Glycine betaine
BV504_RS07775	COG0215	cysteine-tRNA ligase activity
BV504_RS07780	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BV504_RS07785	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BV504_RS07790	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BV504_RS07795	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BV504_RS07805	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BV504_RS07810	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BV504_RS07815	COG0740	serine-type endopeptidase activity
BV504_RS07820	COG0544	peptidyl-prolyl cis-trans isomerase activity
BV504_RS07840	COG0776	regulation of translation
BV504_RS07845	COG0072	phenylalanine-tRNA ligase activity
BV504_RS07850	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BV504_RS07855	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BV504_RS07860	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BV504_RS07865	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BV504_RS07870	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BV504_RS07875	COG2885	chlorophyll binding
BV504_RS07885	COG1612	heme a metabolic process
BV504_RS07910	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
BV504_RS07915	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BV504_RS07920	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BV504_RS07945	COG1643	Atp-dependent helicase
BV504_RS07950	COG1309	transcriptional regulator
BV504_RS07960	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BV504_RS07970	COG0402	S-adenosylhomocysteine deaminase activity
BV504_RS08000	COG1858	cytochrome C peroxidase
BV504_RS08005	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BV504_RS08010	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BV504_RS08015	COG4988	ABC transporter
BV504_RS08020	COG1294	oxidase, subunit
BV504_RS08025	COG1271	oxidase subunit
BV504_RS08035	COG2995	paraquat-inducible protein a
BV504_RS08040	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BV504_RS08040	COG3008	intermembrane lipid transfer
BV504_RS08045	COG3009	Protein conserved in bacteria
BV504_RS08055	COG0513	Belongs to the DEAD box helicase family
BV504_RS08065	COG2807	transmembrane transport
BV504_RS08070	COG0252	asparaginase activity
BV504_RS08090	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BV504_RS08095	COG0602	queuosine metabolic process
BV504_RS08125	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BV504_RS08130	COG0584	glycerophosphoryl diester phosphodiesterase
BV504_RS08135	COG0405	Gamma-glutamyltransferase
BV504_RS08145	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BV504_RS08150	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BV504_RS08160	COG1388	LysM domain
BV504_RS08160	COG1376	ErfK ybiS ycfS ynhG family protein
BV504_RS08165	COG1309	transcriptional regulator
BV504_RS08170	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BV504_RS08180	COG0788	formyltetrahydrofolate deformylase activity
BV504_RS08190	COG0314	molybdopterin synthase activity
BV504_RS08195	COG0315	cyclic pyranopterin monophosphate synthase activity
BV504_RS08200	COG1763	Mo-molybdopterin cofactor biosynthetic process
BV504_RS08210	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BV504_RS08215	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BV504_RS08220	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
BV504_RS08225	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BV504_RS08230	COG2252	PERMEase
BV504_RS08235	COG0307	riboflavin synthase, alpha
BV504_RS08240	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BV504_RS08245	COG2011	ABC-type metal ion transport system permease component
BV504_RS08250	COG1464	Belongs to the NlpA lipoprotein family
BV504_RS08255	COG1956	GAF domain-containing protein
BV504_RS08280	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BV504_RS08285	COG0628	permease
BV504_RS08290	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BV504_RS08295	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BV504_RS08300	COG0717	Belongs to the dCTP deaminase family
BV504_RS08305	COG0489	protein tyrosine kinase activity
BV504_RS08320	COG2154	pterin-4-alpha-carbinolamine dehydratase
BV504_RS08335	COG0534	Mate efflux family protein
BV504_RS08340	COG2353	YceI-like domain
BV504_RS08345	COG3038	cytochrome b561
BV504_RS08370	COG0285	dihydrofolate synthase activity
BV504_RS08375	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BV504_RS08380	COG0159	tryptophan synthase activity
BV504_RS08390	COG0135	phosphoribosylanthranilate isomerase activity
BV504_RS08410	COG0473	3-isopropylmalate dehydrogenase activity
BV504_RS08415	COG0066	3-isopropylmalate dehydratase activity
BV504_RS08420	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BV504_RS08510	COG0456	acetyltransferase
BV504_RS08570	COG1028	Short-chain dehydrogenase reductase Sdr
BV504_RS08580	COG4115	mRNA cleavage
BV504_RS08585	COG1280	lysine exporter protein (LysE YggA)
BV504_RS08660	COG0497	DNA recombination
BV504_RS08680	COG0495	leucyl-tRNA aminoacylation
BV504_RS08705	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BV504_RS08720	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BV504_RS08725	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BV504_RS08730	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BV504_RS08735	COG1805	sodium ion transport
BV504_RS08740	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BV504_RS08750	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BV504_RS08755	COG1376	ErfK ybiS ycfS ynhG family protein
BV504_RS08790	COG0583	DNA-binding transcription factor activity
BV504_RS08795	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BV504_RS08800	COG0321	lipoyl(octanoyl) transferase activity
BV504_RS08805	COG2921	Belongs to the UPF0250 family
BV504_RS08810	COG1686	Belongs to the peptidase S11 family
BV504_RS08820	COG2951	lytic endotransglycosylase activity
BV504_RS08825	COG0772	Belongs to the SEDS family
BV504_RS08830	COG0768	penicillin binding
BV504_RS08835	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BV504_RS08845	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BV504_RS08850	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BV504_RS08865	COG0586	Pfam SNARE associated Golgi protein
BV504_RS08870	COG1280	lysine exporter protein (LysE YggA)
BV504_RS08880	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BV504_RS08890	COG0747	negative chemotaxis
BV504_RS08895	COG0601	transmembrane transport
BV504_RS08900	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BV504_RS08910	COG4608	Belongs to the ABC transporter superfamily
BV504_RS08915	COG0583	DNA-binding transcription factor activity
BV504_RS08920	COG0006	proline dipeptidase activity
BV504_RS08930	COG1063	alcohol dehydrogenase
BV504_RS08935	COG2072	flavoprotein involved in K transport
BV504_RS08940	COG3284	Transcriptional regulator
BV504_RS08945	COG0542	response to heat
BV504_RS08980	COG2828	Protein conserved in bacteria
BV504_RS08985	COG0583	DNA-binding transcription factor activity
BV504_RS08990	COG1492	cobalamin metabolic process
BV504_RS08995	COG2066	Belongs to the glutaminase family
BV504_RS09010	COG1176	ABC-type spermidine putrescine transport system, permease component I
BV504_RS09015	COG1177	transmembrane transport
BV504_RS09020	COG3842	ATPase activity
BV504_RS09025	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BV504_RS09030	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BV504_RS09045	COG1522	sequence-specific DNA binding
BV504_RS09060	COG1030	water channel activity
BV504_RS09075	COG2226	methyltransferase
BV504_RS09105	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BV504_RS09110	COG0456	acetyltransferase
BV504_RS09120	COG1280	lysine exporter protein (LysE YggA)
BV504_RS09160	COG1051	belongs to the nudix hydrolase family
BV504_RS09175	COG0655	NAD(P)H dehydrogenase (quinone) activity
BV504_RS09195	COG4106	trans-aconitate 2-methyltransferase activity
BV504_RS09245	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
BV504_RS09265	COG0625	glutathione transferase activity
BV504_RS09270	COG1819	glycosyl
BV504_RS09285	COG0534	Mate efflux family protein
BV504_RS09295	COG0513	Belongs to the DEAD box helicase family
BV504_RS09300	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BV504_RS09380	COG2875	Belongs to the precorrin methyltransferase family
BV504_RS09395	COG2099	Precorrin-6x reductase
BV504_RS09430	COG1797	cobyrinic acid a,c-diamide synthase activity
BV504_RS09450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BV504_RS09460	COG2207	Transcriptional regulator
BV504_RS09465	COG0697	spore germination
BV504_RS09470	COG0183	Belongs to the thiolase family
BV504_RS09480	COG0113	porphobilinogen synthase activity
BV504_RS09485	COG3246	L-lysine catabolic process to acetate
BV504_RS09490	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BV504_RS09495	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BV504_RS09505	COG4206	TonB-dependent receptor
BV504_RS09520	COG0406	alpha-ribazole phosphatase activity
BV504_RS09525	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BV504_RS09535	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BV504_RS09540	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BV504_RS09545	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BV504_RS09550	COG1538	Outer membrane efflux protein
BV504_RS09570	COG0837	glucose binding
BV504_RS09580	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BV504_RS09585	COG1621	beta-fructofuranosidase activity
BV504_RS09625	COG2182	Extracellular solute-binding protein
BV504_RS09635	COG3833	ABC-type maltose transport systems, permease component
BV504_RS09645	COG0366	Alpha amylase catalytic
BV504_RS09650	COG2909	trisaccharide binding
BV504_RS09660	COG1653	transport
BV504_RS09675	COG0366	Alpha amylase catalytic
BV504_RS09680	COG3842	ATPase activity
BV504_RS09685	COG1609	Transcriptional regulator
BV504_RS09695	COG0469	pyruvate kinase activity
BV504_RS09700	COG1803	Methylglyoxal synthase
BV504_RS09710	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BV504_RS09710	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BV504_RS09715	COG1105	Belongs to the carbohydrate kinase PfkB family
BV504_RS09720	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BV504_RS09720	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
BV504_RS09720	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BV504_RS09725	COG0166	Belongs to the GPI family
BV504_RS09750	COG0640	Transcriptional regulator
BV504_RS09765	COG1335	isochorismatase
BV504_RS09770	COG1028	Short-chain dehydrogenase reductase Sdr
BV504_RS09780	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BV504_RS09805	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BV504_RS09810	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BV504_RS09810	COG2010	Cytochrome c
BV504_RS09845	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BV504_RS09860	COG0517	IMP dehydrogenase activity
BV504_RS09860	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BV504_RS09860	COG0617	tRNA 3'-terminal CCA addition
BV504_RS09880	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BV504_RS09885	COG0506	proline dehydrogenase activity
BV504_RS09885	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BV504_RS09885	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BV504_RS09890	COG3047	cAMP biosynthetic process
BV504_RS09895	COG3098	single-species biofilm formation
BV504_RS09910	COG0189	ligase activity
BV504_RS09920	COG2949	membrane
BV504_RS09930	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BV504_RS09935	COG0719	Fe-S assembly protein
BV504_RS09940	COG0396	ATPase activity
BV504_RS09945	COG0719	Fe-S assembly protein
BV504_RS09960	COG2824	Alkylphosphonate utilization operon protein PhnA
BV504_RS10000	COG0183	Belongs to the thiolase family
BV504_RS10025	COG0589	response to stress
BV504_RS10030	COG0488	(ABC) transporter
BV504_RS10040	COG0318	PFAM AMP-dependent synthetase and ligase
BV504_RS10045	COG0183	Belongs to the thiolase family
BV504_RS10050	COG1960	acyl-CoA dehydrogenase activity
BV504_RS10055	COG0318	PFAM AMP-dependent synthetase and ligase
BV504_RS10065	COG0084	hydrolase, TatD family'
BV504_RS10075	COG3101	peptidyl-lysine hydroxylation
BV504_RS10105	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
BV504_RS10130	COG1960	acyl-CoA dehydrogenase activity
BV504_RS10145	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BV504_RS10150	COG1309	transcriptional regulator
BV504_RS10155	COG0183	Belongs to the thiolase family
BV504_RS10160	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BV504_RS10170	COG0798	PFAM Bile acid sodium symporter
BV504_RS10200	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BV504_RS10205	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BV504_RS10215	COG0573	inorganic phosphate transmembrane transporter activity
BV504_RS10230	COG2814	Major facilitator Superfamily
BV504_RS10235	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BV504_RS10250	COG2853	Lipoprotein
BV504_RS10260	COG1643	Atp-dependent helicase
BV504_RS10265	COG0318	PFAM AMP-dependent synthetase and ligase
BV504_RS10270	COG0121	glutamine amidotransferase
BV504_RS10285	COG2983	Belongs to the UPF0260 family
BV504_RS10295	COG3100	YcgL domain-containing protein
BV504_RS10305	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BV504_RS10310	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BV504_RS10315	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BV504_RS10320	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BV504_RS10325	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BV504_RS10340	COG0322	excinuclease ABC activity
BV504_RS10365	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BV504_RS10380	COG0776	regulation of translation
BV504_RS10390	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BV504_RS10395	COG0284	orotidine-5'-phosphate decarboxylase activity
BV504_RS10400	COG1555	photosystem II stabilization
BV504_RS10400	COG1596	polysaccharide export
BV504_RS10415	COG0372	Belongs to the citrate synthase family
BV504_RS10420	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BV504_RS10425	COG1802	Transcriptional regulator
BV504_RS10435	COG0175	sulfate reduction
BV504_RS10445	COG3118	belongs to the thioredoxin family
BV504_RS10450	COG0628	permease
BV504_RS10460	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BV504_RS10475	COG0247	lactate metabolic process
BV504_RS10475	COG0277	FAD linked oxidase domain protein
BV504_RS10490	COG5002	protein histidine kinase activity
BV504_RS10495	COG0134	indole-3-glycerol-phosphate synthase activity
BV504_RS10500	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BV504_RS10505	COG0512	Glutamine amidotransferase of anthranilate synthase
BV504_RS10520	COG1028	Short-chain dehydrogenase reductase Sdr
BV504_RS10530	COG1250	3-hydroxyacyl-CoA dehydrogenase
BV504_RS10530	COG1024	Enoyl-CoA hydratase
BV504_RS10535	COG1960	acyl-CoA dehydrogenase activity
BV504_RS10550	COG0559	Belongs to the binding-protein-dependent transport system permease family
BV504_RS10575	COG0251	oxidation-reduction process
BV504_RS10585	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BV504_RS10590	COG2918	glutathione biosynthetic process
BV504_RS10605	COG0583	DNA-binding transcription factor activity
BV504_RS10610	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BV504_RS10615	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BV504_RS10620	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BV504_RS10625	COG1011	Hydrolase
BV504_RS10630	COG0494	nUDIX hydrolase
BV504_RS10635	COG0673	inositol 2-dehydrogenase activity
BV504_RS10640	COG0129	dihydroxy-acid dehydratase activity
BV504_RS10645	COG0840	transmembrane signaling receptor activity
BV504_RS10645	COG0840	transmembrane signaling receptor activity
BV504_RS10650	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BV504_RS10660	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BV504_RS10670	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BV504_RS10675	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BV504_RS10685	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BV504_RS10685	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BV504_RS10690	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BV504_RS10695	COG0366	Alpha amylase catalytic
BV504_RS10705	COG2391	methyltransferase activity
BV504_RS10725	COG0840	transmembrane signaling receptor activity
BV504_RS10730	COG1215	transferase activity, transferring glycosyl groups
BV504_RS10740	COG2885	chlorophyll binding
BV504_RS10755	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BV504_RS10760	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BV504_RS10765	COG4181	ATPase activity
BV504_RS10800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BV504_RS10805	COG2274	protein secretion by the type I secretion system
BV504_RS10810	COG1538	Outer membrane efflux protein
BV504_RS10815	COG0697	spore germination
BV504_RS10825	COG1366	Belongs to the anti-sigma-factor antagonist family
BV504_RS10835	COG0488	(ABC) transporter
BV504_RS10845	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
BV504_RS10850	COG0537	adenosine 5'-monophosphoramidase activity
BV504_RS10855	COG3954	Phosphoribulokinase
BV504_RS10865	COG0151	Belongs to the GarS family
BV504_RS10870	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
BV504_RS10875	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BV504_RS10880	COG4067	protein conserved in archaea
BV504_RS10880	COG0189	ligase activity
BV504_RS10885	COG2951	lytic endotransglycosylase activity
BV504_RS10890	COG1320	monovalent cation:proton antiporter activity
BV504_RS10895	COG2212	antiporter activity
BV504_RS10900	COG1863	multisubunit Na H antiporter MnhE subunit
BV504_RS10905	COG0651	ATP synthesis coupled electron transport
BV504_RS10910	COG1006	Multisubunit Na H antiporter MnhC subunit
BV504_RS10915	COG2111	Na H antiporter
BV504_RS10920	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BV504_RS10920	COG2111	Na H antiporter
BV504_RS10925	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BV504_RS10925	COG2111	Na H antiporter
BV504_RS10930	COG1006	Multisubunit Na H antiporter MnhC subunit
BV504_RS10935	COG0651	ATP synthesis coupled electron transport
BV504_RS10940	COG1863	multisubunit Na H antiporter MnhE subunit
BV504_RS10945	COG2212	antiporter activity
BV504_RS10950	COG1320	monovalent cation:proton antiporter activity
BV504_RS10960	COG3046	protein related to deoxyribodipyrimidine photolyase
BV504_RS10980	COG0305	Participates in initiation and elongation during chromosome replication
BV504_RS10985	COG0359	binds to the 23S rRNA
BV504_RS10995	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BV504_RS11000	COG0360	Binds together with S18 to 16S ribosomal RNA
BV504_RS11005	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BV504_RS11010	COG0557	exoribonuclease II activity
BV504_RS11050	COG2719	SpoVR family
BV504_RS11055	COG2718	Belongs to the UPF0229 family
BV504_RS11060	COG2766	serine protein kinase
BV504_RS11070	COG1902	pentaerythritol trinitrate reductase activity
BV504_RS11070	COG0446	pyridine nucleotide-disulphide oxidoreductase
BV504_RS11075	COG0697	spore germination
BV504_RS11080	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BV504_RS11080	COG3153	acetyltransferase
BV504_RS11095	COG1115	amino acid carrier protein
BV504_RS11100	COG0432	Pfam Uncharacterised protein family UPF0047
BV504_RS11105	COG3040	lipid binding
BV504_RS11110	COG0583	DNA-binding transcription factor activity
BV504_RS11115	COG0473	3-isopropylmalate dehydrogenase activity
BV504_RS11120	COG0655	NAD(P)H dehydrogenase (quinone) activity
BV504_RS11140	COG4160	amino acid transport
BV504_RS11145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BV504_RS11150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BV504_RS11160	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BV504_RS11175	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BV504_RS11185	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BV504_RS11190	COG1012	belongs to the aldehyde dehydrogenase family
BV504_RS11195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BV504_RS11220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BV504_RS11230	COG0129	dihydroxy-acid dehydratase activity
BV504_RS11235	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BV504_RS11240	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BV504_RS11245	COG1074	ATP-dependent DNA helicase activity
BV504_RS11250	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BV504_RS11285	COG0697	spore germination
BV504_RS11290	COG0583	DNA-binding transcription factor activity
BV504_RS11305	COG5265	(ABC) transporter
BV504_RS11335	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
BV504_RS11350	COG3070	regulator of competence-specific genes
BV504_RS11365	COG2226	methyltransferase
BV504_RS11375	COG2824	Alkylphosphonate utilization operon protein PhnA
BV504_RS11385	COG2271	Major facilitator Superfamily
BV504_RS11395	COG0488	(ABC) transporter
BV504_RS11405	COG0583	DNA-binding transcription factor activity
BV504_RS11440	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BV504_RS11455	COG0583	DNA-binding transcription factor activity
BV504_RS11460	COG0300	oxidoreductase activity
BV504_RS11505	COG0159	tryptophan synthase activity
BV504_RS11530	COG0583	DNA-binding transcription factor activity
BV504_RS11540	COG0693	protein deglycase activity
BV504_RS11545	COG0583	DNA-binding transcription factor activity
BV504_RS11550	COG0667	Aldo Keto reductase
BV504_RS11570	COG5002	protein histidine kinase activity
BV504_RS11570	COG5001	Diguanylate cyclase
BV504_RS11570	COG3447	MASE1 domain protein
BV504_RS11590	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BV504_RS11620	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BV504_RS11635	COG3938	Belongs to the proline racemase family
BV504_RS11640	COG3321	synthase
BV504_RS11640	COG0604	alcohol dehydrogenase
BV504_RS11640	COG1028	Short-chain dehydrogenase reductase Sdr
BV504_RS11655	COG0598	Magnesium transport protein CorA
BV504_RS11690	COG2308	Evidence 4 Homologs of previously reported genes of
BV504_RS11705	COG1305	Transglutaminase-like
BV504_RS11880	COG4373	Mu-like prophage FluMu protein gp28
BV504_RS11885	COG4383	Mu-like prophage protein gp29
BV504_RS11920	COG4397	Mu-like prophage major head subunit gpT
BV504_RS11990	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
BV504_RS12035	COG0210	DNA helicase
BV504_RS12040	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BV504_RS12045	COG1061	Type III restriction enzyme res subunit
BV504_RS12055	COG1002	Type II restriction enzyme, methylase subunits
BV504_RS12070	COG1132	(ABC) transporter
BV504_RS12080	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BV504_RS12085	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BV504_RS12090	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BV504_RS12095	COG4771	TonB-dependent receptor
BV504_RS12100	COG4771	TonB-dependent receptor
BV504_RS12105	COG0583	DNA-binding transcription factor activity
BV504_RS12115	COG2133	pyrroloquinoline quinone binding
BV504_RS12140	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BV504_RS12160	COG0697	spore germination
BV504_RS12165	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BV504_RS12175	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BV504_RS12180	COG0583	DNA-binding transcription factor activity
BV504_RS12185	COG1760	l-serine dehydratase
BV504_RS12195	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BV504_RS12210	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BV504_RS12215	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BV504_RS12220	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BV504_RS12235	COG0617	tRNA 3'-terminal CCA addition
BV504_RS12240	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BV504_RS12245	COG2967	ApaG domain
BV504_RS12250	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BV504_RS12255	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BV504_RS12260	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BV504_RS12265	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BV504_RS12270	COG3178	'Phosphotransferase
BV504_RS12275	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BV504_RS12280	COG1765	OsmC-like protein
BV504_RS12285	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BV504_RS12290	COG1560	Kdo2-lipid A biosynthetic process
BV504_RS12295	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BV504_RS12315	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BV504_RS12320	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BV504_RS12325	COG0585	pseudouridine synthase activity
BV504_RS12330	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BV504_RS12335	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BV504_RS12340	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BV504_RS12355	COG1737	Transcriptional regulator
BV504_RS12370	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BV504_RS12380	COG0589	response to stress
BV504_RS12385	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BV504_RS12390	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BV504_RS12400	COG0589	response to stress
BV504_RS12405	COG0659	secondary active sulfate transmembrane transporter activity
BV504_RS12410	COG0473	3-isopropylmalate dehydrogenase activity
BV504_RS12415	COG0450	alkyl hydroperoxide reductase
BV504_RS12420	COG1469	GTP cyclohydrolase I activity
BV504_RS12425	COG0523	cobalamin synthesis protein
BV504_RS12445	COG1854	S-ribosylhomocysteine lyase activity
BV504_RS12460	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BV504_RS12465	COG1012	belongs to the aldehyde dehydrogenase family
BV504_RS12470	COG1522	sequence-specific DNA binding
BV504_RS12475	COG3608	succinylglutamate desuccinylase aspartoacylase
BV504_RS12480	COG0006	proline dipeptidase activity
BV504_RS12485	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BV504_RS12495	COG2431	L-lysine efflux transmembrane transporter activity
BV504_RS12500	COG0700	Nucleoside recognition
BV504_RS12515	COG1944	ATP diphosphatase activity
BV504_RS12520	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BV504_RS12520	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BV504_RS12525	COG0306	phosphate transporter
BV504_RS12530	COG1392	Phosphate transport regulator
BV504_RS12540	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BV504_RS12545	COG0009	L-threonylcarbamoyladenylate synthase
BV504_RS12550	COG0613	PHP domain protein
BV504_RS12555	COG2350	Protein conserved in bacteria
BV504_RS12560	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BV504_RS12560	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BV504_RS12570	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BV504_RS12575	COG3115	cell septum assembly
BV504_RS12580	COG1196	nuclear chromosome segregation
BV504_RS12590	COG3088	subunit of a heme lyase
BV504_RS12600	COG1138	Cytochrome C-type biogenesis protein
BV504_RS12605	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
BV504_RS12625	COG4133	protoheme IX ABC transporter activity
BV504_RS12635	COG1739	Uncharacterized protein family UPF0029
BV504_RS12640	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
BV504_RS12675	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BV504_RS12680	COG0527	aspartate kinase activity
BV504_RS12685	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BV504_RS12690	COG2137	regulation of response to DNA damage stimulus
BV504_RS12695	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BV504_RS12700	COG1546	Belongs to the CinA family
BV504_RS12705	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BV504_RS12710	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BV504_RS12720	COG0148	phosphopyruvate hydratase activity
BV504_RS12730	COG0504	CTP synthase activity
BV504_RS12735	COG0493	'glutamate synthase
BV504_RS12740	COG0069	glutamate synthase activity
BV504_RS12740	COG0067	glutamate synthase
BV504_RS12740	COG0070	glutamate synthase
BV504_RS12745	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BV504_RS12750	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BV504_RS12800	COG0579	oxidoreductase
BV504_RS12805	COG1802	Transcriptional regulator
BV504_RS12810	COG1960	acyl-CoA dehydrogenase activity
BV504_RS12815	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BV504_RS12820	COG5001	Diguanylate cyclase
BV504_RS12820	COG3300	MHYT domain
BV504_RS12840	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BV504_RS12845	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BV504_RS12855	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BV504_RS12860	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BV504_RS12865	COG2161	toxin-antitoxin pair type II binding
BV504_RS12870	COG4115	mRNA cleavage
BV504_RS12875	COG1234	tRNA 3'-trailer cleavage
BV504_RS12880	COG4115	mRNA cleavage
BV504_RS12885	COG2161	toxin-antitoxin pair type II binding
BV504_RS12925	COG0747	negative chemotaxis
BV504_RS12930	COG0601	transmembrane transport
BV504_RS12935	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BV504_RS12940	COG4172	Belongs to the ABC transporter superfamily
BV504_RS12945	COG0277	FAD linked oxidase domain protein
BV504_RS12950	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BV504_RS12965	COG2423	ornithine cyclodeaminase activity
BV504_RS12970	COG0251	oxidation-reduction process
BV504_RS12980	COG0438	transferase activity, transferring glycosyl groups
BV504_RS12990	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BV504_RS13065	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BV504_RS13070	COG0343	queuine tRNA-ribosyltransferase activity
BV504_RS13075	COG1862	Preprotein translocase
BV504_RS13110	COG1104	cysteine desulfurase activity
BV504_RS13120	COG0105	UTP biosynthetic process
BV504_RS13125	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BV504_RS13140	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BV504_RS13145	COG0124	histidyl-tRNA synthetase
BV504_RS13160	COG1160	GTP binding
BV504_RS13185	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BV504_RS13190	COG0408	coproporphyrinogen oxidase activity
BV504_RS13195	COG0009	L-threonylcarbamoyladenylate synthase
BV504_RS13200	COG0758	DNA mediated transformation
BV504_RS13210	COG0242	peptide deformylase activity
BV504_RS13215	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BV504_RS13225	COG3360	Dodecin
BV504_RS13230	COG0569	domain protein
BV504_RS13235	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BV504_RS13250	COG3148	PFAM DTW domain containing protein
BV504_RS13255	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BV504_RS13260	COG0156	8-amino-7-oxononanoate synthase activity
BV504_RS13265	COG2267	carboxylic ester hydrolase activity
BV504_RS13270	COG2226	methyltransferase
BV504_RS13275	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BV504_RS13285	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BV504_RS13290	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
BV504_RS13295	COG0531	amino acid
BV504_RS13300	COG4302	ethanolamine ammonia-lyase activity
BV504_RS13315	COG2226	methyltransferase
BV504_RS13330	COG0523	cobalamin synthesis protein
BV504_RS13345	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BV504_RS13350	COG0564	pseudouridine synthase activity
BV504_RS13370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BV504_RS13375	COG0444	Belongs to the ABC transporter superfamily
BV504_RS13380	COG4608	Belongs to the ABC transporter superfamily
BV504_RS13400	COG1966	Carbon starvation protein
BV504_RS13405	COG0444	Belongs to the ABC transporter superfamily
BV504_RS13420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BV504_RS13440	COG4139	cobalamin transport
BV504_RS13465	COG0795	lipopolysaccharide-transporting ATPase activity
BV504_RS13470	COG0795	lipopolysaccharide-transporting ATPase activity
BV504_RS13475	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BV504_RS13480	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BV504_RS13505	COG0525	valine-tRNA ligase activity
BV504_RS13510	COG1073	alpha beta
BV504_RS13525	COG0583	DNA-binding transcription factor activity
BV504_RS13550	COG4134	Bacterial extracellular solute-binding protein
BV504_RS13555	COG4135	transport system, permease component
BV504_RS13560	COG4136	ATPase activity
BV504_RS13575	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BV504_RS13585	COG3706	GGDEF domain
BV504_RS13600	COG0346	lactoylglutathione lyase activity
BV504_RS13640	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BV504_RS13650	COG0248	Ppx GppA phosphatase
BV504_RS13655	COG0037	tRNA processing
BV504_RS13660	COG0825	malonyl-CoA metabolic process
BV504_RS13665	COG0587	DNA-directed DNA polymerase activity
BV504_RS13670	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BV504_RS13675	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BV504_RS13680	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BV504_RS13685	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BV504_RS13690	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BV504_RS13710	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BV504_RS13725	COG0233	cytoplasmic translational termination
BV504_RS13730	COG0528	UMP kinase activity
BV504_RS13735	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BV504_RS13740	COG0052	Belongs to the universal ribosomal protein uS2 family
BV504_RS13745	COG0024	Methionine aminopeptidase
BV504_RS13750	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BV504_RS13755	COG0436	Aminotransferase
BV504_RS13770	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BV504_RS13790	COG0686	Belongs to the AlaDH PNT family
BV504_RS13800	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BV504_RS13805	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BV504_RS13810	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BV504_RS13815	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BV504_RS13820	COG2003	Belongs to the UPF0758 family
BV504_RS13825	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BV504_RS13830	COG0756	dUTP diphosphatase activity
BV504_RS13840	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BV504_RS13845	COG1309	transcriptional regulator
BV504_RS13855	COG2177	Part of the ABC transporter FtsEX involved in
BV504_RS13860	COG2884	Cell division ATP-binding protein ftsE
BV504_RS13865	COG0552	protein localization to endoplasmic reticulum
BV504_RS13870	COG0742	ribosomal rna small subunit methyltransferase
BV504_RS13890	COG0271	Belongs to the BolA IbaG family
BV504_RS13895	COG2814	Major facilitator Superfamily
BV504_RS13905	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BV504_RS13925	COG2217	Heavy metal translocating P-type atpase
BV504_RS13935	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BV504_RS13950	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BV504_RS13960	COG0335	large ribosomal subunit rRNA binding
BV504_RS13965	COG0336	Belongs to the RNA methyltransferase TrmD family
BV504_RS13970	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BV504_RS13975	COG0228	four-way junction DNA binding
BV504_RS13980	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BV504_RS13985	COG4137	Cytochrome C assembly protein
BV504_RS13990	COG4536	flavin adenine dinucleotide binding
BV504_RS14010	COG1025	Belongs to the peptidase M16 family
BV504_RS14015	COG2925	Exonuclease
BV504_RS14020	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BV504_RS14025	COG2894	cell division
BV504_RS14030	COG0850	regulation of cytokinetic process
BV504_RS14040	COG1028	Short-chain dehydrogenase reductase Sdr
BV504_RS14075	COG3501	Rhs element vgr protein
BV504_RS14105	COG3829	transcription factor binding
BV504_RS14165	COG0180	Tryptophanyl-tRNA synthetase
BV504_RS14190	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BV504_RS14195	COG1047	Peptidyl-prolyl cis-trans
BV504_RS14205	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BV504_RS14210	COG0196	riboflavin kinase activity
BV504_RS14220	COG0268	Binds directly to 16S ribosomal RNA
BV504_RS14230	COG3118	belongs to the thioredoxin family
BV504_RS14235	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BV504_RS14275	COG0667	Aldo Keto reductase
BV504_RS14280	COG3022	response to hydroperoxide
BV504_RS14315	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BV504_RS14320	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BV504_RS14345	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BV504_RS14360	COG1489	DNA binding
BV504_RS14365	COG0436	Aminotransferase
BV504_RS14370	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BV504_RS14375	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BV504_RS14380	COG3852	Histidine kinase
BV504_RS14385	COG2204	response regulator
BV504_RS14390	COG0617	tRNA 3'-terminal CCA addition
BV504_RS14395	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BV504_RS14400	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BV504_RS14405	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BV504_RS14410	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BV504_RS14425	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BV504_RS14435	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BV504_RS14445	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BV504_RS14450	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BV504_RS14455	COG1012	belongs to the aldehyde dehydrogenase family
BV504_RS14460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BV504_RS14465	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BV504_RS14475	COG3314	Sporulation integral membrane protein YlbJ
BV504_RS14500	COG1175	transmembrane transport
BV504_RS14505	COG0395	ABC-type sugar transport system, permease component
BV504_RS14525	COG0235	Class ii aldolase
BV504_RS14530	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
BV504_RS14535	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BV504_RS14545	COG0583	DNA-binding transcription factor activity
BV504_RS14560	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BV504_RS14565	COG1349	DNA-binding transcription factor activity
BV504_RS14580	COG3842	ATPase activity
BV504_RS14585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BV504_RS14595	COG2814	Major facilitator Superfamily
BV504_RS14600	COG4977	sequence-specific DNA binding
BV504_RS14620	COG3766	membrane
BV504_RS14630	COG0754	glutathionylspermidine amidase activity
BV504_RS14635	COG0840	transmembrane signaling receptor activity
BV504_RS14645	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BV504_RS14655	COG0745	RESPONSE REGULATOR receiver
BV504_RS14680	COG0521	Mo-molybdopterin cofactor biosynthetic process
BV504_RS14695	COG0437	4 iron, 4 sulfur cluster binding
BV504_RS14700	COG3383	formate dehydrogenase (NAD+) activity
BV504_RS14730	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BV504_RS14735	COG0746	molybdenum cofactor guanylyltransferase activity
BV504_RS14740	COG0303	'Molybdopterin
BV504_RS14745	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BV504_RS14750	COG0523	cobalamin synthesis protein
BV504_RS14770	COG1953	Uracil, thiamine, allantoin
BV504_RS14800	COG0840	transmembrane signaling receptor activity
BV504_RS14805	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BV504_RS14810	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BV504_RS14815	COG1116	anion transmembrane transporter activity
BV504_RS14820	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BV504_RS14825	COG0402	S-adenosylhomocysteine deaminase activity
BV504_RS14840	COG0456	acetyltransferase
BV504_RS14855	COG2818	Glycosylase
BV504_RS14860	COG1063	alcohol dehydrogenase
BV504_RS14865	COG1522	sequence-specific DNA binding
BV504_RS14870	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BV504_RS14875	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BV504_RS14900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BV504_RS14905	COG1120	ATPase activity
BV504_RS14935	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BV504_RS14940	COG1522	sequence-specific DNA binding
BV504_RS14945	COG1309	transcriptional regulator
BV504_RS14970	COG2188	Transcriptional regulator
BV504_RS14985	COG0318	PFAM AMP-dependent synthetase and ligase
BV504_RS14990	COG1441	menaquinone biosynthetic process
BV504_RS15000	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
BV504_RS15010	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BV504_RS15015	COG1053	succinate dehydrogenase
BV504_RS15025	COG0596	Alpha beta hydrolase
BV504_RS15030	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BV504_RS15035	COG1169	isochorismate synthase
BV504_RS15045	COG1575	Belongs to the MenA family. Type 1 subfamily
BV504_RS15065	COG2329	Antibiotic biosynthesis monooxygenase
BV504_RS15070	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BV504_RS15080	COG0303	'Molybdopterin
BV504_RS15085	COG0521	Mo-molybdopterin cofactor biosynthetic process
BV504_RS15095	COG2181	nitrate reductase activity
BV504_RS15100	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BV504_RS15105	COG1140	nitrate reductase beta subunit
BV504_RS15110	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BV504_RS15115	COG0826	peptidase U32
BV504_RS15120	COG0826	peptidase U32
BV504_RS15135	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BV504_RS15140	COG1959	2 iron, 2 sulfur cluster binding
BV504_RS15150	COG1017	nitric oxide dioxygenase activity
BV504_RS15150	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BV504_RS15155	COG3154	lipid carrier protein
BV504_RS15175	COG3850	Histidine kinase
BV504_RS15180	COG2197	response regulator
BV504_RS15185	COG2223	nitrite transmembrane transporter activity
BV504_RS15195	COG2223	nitrite transmembrane transporter activity
BV504_RS15220	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BV504_RS15225	COG1012	belongs to the aldehyde dehydrogenase family
BV504_RS15230	COG0531	amino acid
BV504_RS15235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BV504_RS15250	COG1396	sequence-specific DNA binding
BV504_RS15250	COG1917	Cupin 2, conserved barrel domain protein
BV504_RS15255	COG1757	Na H antiporter
BV504_RS15260	COG1012	belongs to the aldehyde dehydrogenase family
BV504_RS15270	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BV504_RS15275	COG0174	glutamine synthetase
BV504_RS15280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BV504_RS15285	COG0006	proline dipeptidase activity
BV504_RS15295	COG1902	pentaerythritol trinitrate reductase activity
BV504_RS15300	COG2957	Belongs to the agmatine deiminase family
BV504_RS15305	COG1757	Na H antiporter
BV504_RS15310	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BV504_RS15320	COG1012	belongs to the aldehyde dehydrogenase family
BV504_RS15335	COG0488	(ABC) transporter
BV504_RS15360	COG1012	belongs to the aldehyde dehydrogenase family
BV504_RS15365	COG1028	Short-chain dehydrogenase reductase Sdr
BV504_RS15375	COG1250	3-hydroxyacyl-CoA dehydrogenase
BV504_RS15385	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BV504_RS15390	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BV504_RS15390	COG0519	Catalyzes the synthesis of GMP from XMP
BV504_RS15410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BV504_RS15420	COG4221	oxidoreductase activity
BV504_RS15425	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BV504_RS15440	COG2084	Dehydrogenase
BV504_RS15445	COG1012	belongs to the aldehyde dehydrogenase family
BV504_RS15450	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BV504_RS15450	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BV504_RS15460	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BV504_RS15465	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BV504_RS15470	COG3622	Belongs to the hyi family
BV504_RS15475	COG0235	Class ii aldolase
BV504_RS15480	COG3395	kinase activity
BV504_RS15485	COG2084	Dehydrogenase
BV504_RS15490	COG1609	Transcriptional regulator
BV504_RS15505	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BV504_RS15515	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BV504_RS15525	COG2186	Transcriptional regulator
BV504_RS15535	COG0583	DNA-binding transcription factor activity
BV504_RS15550	COG4771	TonB-dependent receptor
BV504_RS15555	COG3720	iron ion transport
BV504_RS15560	COG4558	Periplasmic binding protein
BV504_RS15565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BV504_RS15575	COG1595	DNA-templated transcription, initiation
BV504_RS15600	COG1595	DNA-templated transcription, initiation
BV504_RS15610	COG4771	TonB-dependent receptor
BV504_RS15640	COG2832	Protein of unknown function (DUF454)
BV504_RS15660	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BV504_RS15675	COG1802	Transcriptional regulator
BV504_RS15700	COG3395	kinase activity
BV504_RS15705	COG0235	Class ii aldolase
BV504_RS15710	COG1522	sequence-specific DNA binding
BV504_RS15715	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BV504_RS15720	COG0673	inositol 2-dehydrogenase activity
BV504_RS15730	COG3962	Belongs to the TPP enzyme family
BV504_RS15735	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BV504_RS15745	COG1172	Belongs to the binding-protein-dependent transport system permease family
BV504_RS15760	COG0673	inositol 2-dehydrogenase activity
BV504_RS15765	COG3718	enzyme involved in inositol metabolism
BV504_RS15785	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BV504_RS15790	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BV504_RS15795	COG3833	ABC-type maltose transport systems, permease component
BV504_RS15800	COG3842	ATPase activity
BV504_RS15805	COG1840	ABC-type Fe3 transport system, periplasmic component
BV504_RS15830	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BV504_RS15840	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BV504_RS15845	COG0583	DNA-binding transcription factor activity
BV504_RS15850	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BV504_RS15855	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BV504_RS15860	COG1984	allophanate hydrolase subunit 2
BV504_RS15870	COG2309	aminopeptidase activity
BV504_RS15875	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BV504_RS15885	COG2010	Cytochrome c
BV504_RS15885	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BV504_RS15890	COG2080	2 iron, 2 sulfur cluster binding
BV504_RS15900	COG0596	Alpha beta hydrolase
BV504_RS15905	COG3473	Maleate cis-trans isomerase
BV504_RS15910	COG1335	isochorismatase
BV504_RS15915	COG1846	Transcriptional regulator
BV504_RS15920	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BV504_RS15920	COG2010	Cytochrome c
BV504_RS15935	COG0840	transmembrane signaling receptor activity
BV504_RS15950	COG1704	LemA family
BV504_RS15955	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
BV504_RS15980	COG0535	radical SAM domain protein
BV504_RS16095	COG2205	protein histidine kinase activity
BV504_RS16105	COG2873	o-acetylhomoserine
BV504_RS16110	COG1760	l-serine dehydratase
BV504_RS16125	COG0446	pyridine nucleotide-disulphide oxidoreductase
BV504_RS16125	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BV504_RS16140	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BV504_RS16160	COG1902	pentaerythritol trinitrate reductase activity
BV504_RS16160	COG0446	pyridine nucleotide-disulphide oxidoreductase
BV504_RS16165	COG3383	formate dehydrogenase (NAD+) activity
BV504_RS16175	COG1063	alcohol dehydrogenase
BV504_RS16180	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BV504_RS16190	COG0697	spore germination
BV504_RS16200	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BV504_RS16205	COG2181	nitrate reductase activity
BV504_RS16205	COG0247	lactate metabolic process
BV504_RS16210	COG1902	pentaerythritol trinitrate reductase activity
BV504_RS16210	COG0446	pyridine nucleotide-disulphide oxidoreductase
BV504_RS16250	COG0501	Belongs to the peptidase M48B family
BV504_RS16260	COG0596	Alpha beta hydrolase
BV504_RS16280	COG0583	DNA-binding transcription factor activity
BV504_RS16310	COG1024	Enoyl-CoA hydratase
BV504_RS16325	COG2079	MmgE PrpD family protein
BV504_RS16345	COG0745	RESPONSE REGULATOR receiver
BV504_RS16350	COG2205	protein histidine kinase activity
BV504_RS16360	COG1538	Outer membrane efflux protein
BV504_RS16365	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BV504_RS16370	COG1129	ABC transporter
BV504_RS16370	COG0842	Transport permease protein
BV504_RS16375	COG0842	Transport permease protein
BV504_RS16380	COG0348	domain, Protein
BV504_RS16385	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BV504_RS16390	COG1271	oxidase subunit
BV504_RS16395	COG1294	oxidase, subunit
BV504_RS16410	COG2910	NAD(P)H-binding
BV504_RS16425	COG1473	amidohydrolase
BV504_RS16430	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BV504_RS16435	COG0583	DNA-binding transcription factor activity
BV504_RS16445	COG1278	Cold shock
BV504_RS16450	COG0583	DNA-binding transcription factor activity
BV504_RS16455	COG1012	belongs to the aldehyde dehydrogenase family
BV504_RS16460	COG1757	Na H antiporter
BV504_RS16465	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BV504_RS16470	COG5383	Protein conserved in bacteria
BV504_RS16475	COG0247	lactate metabolic process
BV504_RS16475	COG0277	FAD linked oxidase domain protein
BV504_RS16480	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BV504_RS16485	COG2358	TRAP transporter, solute receptor (TAXI family
BV504_RS16495	COG0583	DNA-binding transcription factor activity
BV504_RS16505	COG3195	allantoin biosynthetic process
BV504_RS16505	COG3648	Uricase
BV504_RS16535	COG2084	Dehydrogenase
BV504_RS16540	COG3622	Belongs to the hyi family
BV504_RS16545	COG3960	tartronate-semialdehyde synthase activity
BV504_RS16550	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
BV504_RS16555	COG3257	ureidoglycine aminohydrolase activity
BV504_RS16560	COG1414	Transcriptional regulator
BV504_RS16585	COG2351	hydroxyisourate hydrolase activity
BV504_RS16625	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BV504_RS16630	COG1960	acyl-CoA dehydrogenase activity
BV504_RS16635	COG0583	DNA-binding transcription factor activity
BV504_RS16640	COG3327	negative regulation of DNA-templated transcription, initiation
BV504_RS16655	COG1024	Enoyl-CoA hydratase
BV504_RS16660	COG1024	Enoyl-CoA hydratase
BV504_RS16665	COG1250	3-hydroxyacyl-CoA dehydrogenase
BV504_RS16670	COG2050	protein possibly involved in aromatic compounds catabolism
BV504_RS16675	COG0183	Belongs to the thiolase family
BV504_RS16685	COG3396	Phenylacetate-CoA oxygenase
BV504_RS16690	COG3460	Phenylacetate-CoA oxygenase
BV504_RS16695	COG3396	Phenylacetate-CoA oxygenase
BV504_RS16700	COG2151	metal-sulfur cluster biosynthetic enzyme
BV504_RS16705	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BV504_RS16710	COG2030	dehydratase
BV504_RS16710	COG1012	belongs to the aldehyde dehydrogenase family
BV504_RS16750	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
BV504_RS16760	COG0625	glutathione transferase activity
BV504_RS16770	COG1522	sequence-specific DNA binding
BV504_RS16785	COG0733	neurotransmitter:sodium symporter activity
BV504_RS16800	COG1522	sequence-specific DNA binding
BV504_RS16815	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BV504_RS16825	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BV504_RS16830	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
BV504_RS16840	COG1288	antiporter activity
BV504_RS16845	COG1473	amidohydrolase
BV504_RS16850	COG0583	DNA-binding transcription factor activity
BV504_RS16855	COG1280	lysine exporter protein (LysE YggA)
BV504_RS16875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BV504_RS16880	COG1120	ATPase activity
BV504_RS16910	COG2204	response regulator
BV504_RS16915	COG4191	Histidine kinase
BV504_RS16920	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BV504_RS16935	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BV504_RS16945	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BV504_RS16945	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BV504_RS16950	COG0028	Belongs to the TPP enzyme family
BV504_RS16960	COG1012	belongs to the aldehyde dehydrogenase family
BV504_RS16965	COG0583	DNA-binding transcription factor activity
BV504_RS16970	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BV504_RS16980	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BV504_RS16985	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BV504_RS16985	COG0473	3-isopropylmalate dehydrogenase activity
BV504_RS16990	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BV504_RS16995	COG2186	Transcriptional regulator
BV504_RS17000	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BV504_RS17010	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BV504_RS17020	COG1028	Short-chain dehydrogenase reductase Sdr
BV504_RS17025	COG1028	Short-chain dehydrogenase reductase Sdr
BV504_RS17030	COG0022	dehydrogenase e1 component
BV504_RS17040	COG0508	dehydrogenase complex catalyzes the overall conversion of
BV504_RS17045	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BV504_RS17055	COG2897	thiosulfate sulfurtransferase activity
BV504_RS17060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BV504_RS17085	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BV504_RS17095	COG0277	FAD linked oxidase domain protein
BV504_RS17100	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BV504_RS17105	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BV504_RS17105	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BV504_RS17110	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BV504_RS17110	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BV504_RS17140	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BV504_RS17145	COG0830	nickel cation binding
BV504_RS17150	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
BV504_RS17155	COG0804	urea catabolic process
BV504_RS17160	COG0832	Belongs to the urease beta subunit family
BV504_RS17165	COG0831	urea catabolic process
BV504_RS17185	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BV504_RS17190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BV504_RS17210	COG0829	nickel cation binding
BV504_RS17220	COG1999	signal sequence binding
BV504_RS17240	COG2375	cellular response to nickel ion
BV504_RS17240	COG1132	(ABC) transporter
BV504_RS17245	COG1132	(ABC) transporter
BV504_RS17250	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BV504_RS17255	COG4605	iron ion homeostasis
BV504_RS17265	COG4607	ABC-type enterochelin transport system periplasmic component
BV504_RS17270	COG4774	siderophore transport
BV504_RS17275	COG1024	Enoyl-CoA hydratase
BV504_RS17295	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BV504_RS17300	COG0318	PFAM AMP-dependent synthetase and ligase
BV504_RS17325	COG0183	Belongs to the thiolase family
BV504_RS17360	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
BV504_RS17380	COG4565	transcriptional regulatory protein
BV504_RS17385	COG3290	protein histidine kinase activity
BV504_RS17395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BV504_RS17405	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BV504_RS17410	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BV504_RS17415	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BV504_RS17430	COG0668	transmembrane transport
BV504_RS17435	COG1238	metal cluster binding
BV504_RS17450	COG1054	Belongs to the UPF0176 family
BV504_RS17455	COG1741	Belongs to the pirin family
BV504_RS17460	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BV504_RS17470	COG0142	geranyltranstransferase activity
BV504_RS17475	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BV504_RS17480	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BV504_RS17490	COG1272	protein, Hemolysin III
BV504_RS17510	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BV504_RS17515	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BV504_RS17520	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BV504_RS17525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BV504_RS17535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BV504_RS17540	COG4597	amino acid ABC transporter
BV504_RS17545	COG0765	amino acid transport
BV504_RS17550	COG1126	abc transporter atp-binding protein
BV504_RS17555	COG0251	oxidation-reduction process
BV504_RS17575	COG3639	organic phosphonate transmembrane transporter activity
BV504_RS17590	COG0840	transmembrane signaling receptor activity
BV504_RS17595	COG0840	transmembrane signaling receptor activity
BV504_RS17600	COG0840	transmembrane signaling receptor activity
BV504_RS17605	COG0583	DNA-binding transcription factor activity
BV504_RS17620	COG0004	ammonium transporteR
BV504_RS17655	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BV504_RS17660	COG0606	chelatase, subunit chli
BV504_RS17675	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BV504_RS17685	COG1879	ABC-type sugar transport system periplasmic component
BV504_RS17690	COG1172	Belongs to the binding-protein-dependent transport system permease family
BV504_RS17695	COG1129	ABC transporter
BV504_RS17700	COG0673	inositol 2-dehydrogenase activity
BV504_RS17710	COG1609	Transcriptional regulator
BV504_RS17715	COG2363	Small membrane protein
BV504_RS17725	COG2022	thiamine diphosphate biosynthetic process
BV504_RS17730	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BV504_RS17735	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BV504_RS17740	COG0679	Auxin Efflux Carrier
BV504_RS17760	COG0545	Peptidyl-prolyl cis-trans isomerase
BV504_RS17765	COG0589	response to stress
BV504_RS17770	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BV504_RS17775	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BV504_RS17780	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BV504_RS17790	COG0488	(ABC) transporter
BV504_RS17795	COG1490	D-aminoacyl-tRNA deacylase activity
BV504_RS17810	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BV504_RS17825	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BV504_RS17835	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BV504_RS17840	COG1011	Hydrolase
BV504_RS17845	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BV504_RS17855	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BV504_RS17860	COG0019	diaminopimelate decarboxylase activity
BV504_RS17870	COG0165	Argininosuccinate lyase
BV504_RS17880	COG0181	hydroxymethylbilane synthase activity
BV504_RS17900	COG1970	mechanosensitive ion channel activity
BV504_RS17905	COG0589	response to stress
BV504_RS17915	COG3135	benzoate transporter
BV504_RS17925	COG0411	ABC transporter
BV504_RS17940	COG0683	leucine binding
BV504_RS17980	COG4829	muconolactone delta-isomerase
BV504_RS17985	COG4948	Mandelate Racemase Muconate Lactonizing
BV504_RS18005	COG3246	L-lysine catabolic process to acetate
BV504_RS18025	COG1289	transmembrane transporter activity
BV504_RS18045	COG0076	glutamate decarboxylase activity
BV504_RS18050	COG2985	domain, Protein
BV504_RS18055	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BV504_RS18065	COG0662	Cupin 2, conserved barrel domain protein
BV504_RS18080	COG1024	Enoyl-CoA hydratase
BV504_RS18090	COG1960	acyl-CoA dehydrogenase activity
BV504_RS18115	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BV504_RS18155	COG0318	PFAM AMP-dependent synthetase and ligase
BV504_RS18165	COG1012	belongs to the aldehyde dehydrogenase family
BV504_RS18180	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BV504_RS18200	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BV504_RS18205	COG3485	protocatechuate 3,4-dioxygenase
BV504_RS18210	COG3485	protocatechuate 3,4-dioxygenase
BV504_RS18215	COG0583	DNA-binding transcription factor activity
BV504_RS18220	COG0596	Alpha beta hydrolase
BV504_RS18225	COG0183	Belongs to the thiolase family
BV504_RS18230	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BV504_RS18235	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BV504_RS18260	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BV504_RS18265	COG3185	4-Hydroxyphenylpyruvate dioxygenase
BV504_RS18265	COG1082	Xylose isomerase domain protein TIM barrel
BV504_RS18270	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BV504_RS18275	COG0679	Auxin Efflux Carrier
BV504_RS18280	COG1028	Short-chain dehydrogenase reductase Sdr
BV504_RS18295	COG3181	Tripartite tricarboxylate transporter family receptor
BV504_RS18300	COG1414	Transcriptional regulator
BV504_RS18310	COG1801	Protein of unknown function DUF72
BV504_RS18315	COG0733	neurotransmitter:sodium symporter activity
BV504_RS18325	COG1737	Transcriptional regulator
BV504_RS18330	COG0210	DNA helicase
BV504_RS18335	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BV504_RS18355	COG0581	inorganic phosphate transmembrane transporter activity
BV504_RS18360	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BV504_RS18365	COG0704	Plays a role in the regulation of phosphate uptake
BV504_RS18370	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
BV504_RS18390	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BV504_RS18395	COG3161	chorismate lyase activity
BV504_RS18415	COG0583	DNA-binding transcription factor activity
BV504_RS18420	COG1012	belongs to the aldehyde dehydrogenase family
BV504_RS18430	COG1473	amidohydrolase
BV504_RS18445	COG1289	transmembrane transporter activity
BV504_RS18450	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BV504_RS18455	COG0583	DNA-binding transcription factor activity
BV504_RS18485	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BV504_RS18490	COG1758	RNA polymerase activity
BV504_RS18495	COG0194	GDP metabolic process
BV504_RS18510	COG2814	Major facilitator Superfamily
BV504_RS18570	COG1561	YicC-like family, N-terminal region
BV504_RS18575	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BV504_RS18585	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BV504_RS18590	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BV504_RS18595	COG0210	DNA helicase
BV504_RS18610	COG0456	acetyltransferase
BV504_RS18630	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BV504_RS18640	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BV504_RS18645	COG1477	protein flavinylation
BV504_RS18650	COG1968	undecaprenyl-diphosphatase activity
BV504_RS18655	COG2239	Acts as a magnesium transporter
BV504_RS18670	COG0671	phosphoesterase, PA-phosphatase related
BV504_RS18675	COG2239	Acts as a magnesium transporter
BV504_RS18680	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BV504_RS18685	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BV504_RS18690	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BV504_RS18695	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BV504_RS18700	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BV504_RS18705	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BV504_RS18715	COG0356	it plays a direct role in the translocation of protons across the membrane
BV504_RS18725	COG1475	DNA binding
BV504_RS18730	COG1192	Involved in chromosome partitioning
BV504_RS18735	COG0357	Ribosomal RNA small subunit methyltransferase G
BV504_RS18740	COG0445	tRNA wobble uridine modification
BV504_RS18745	COG1126	abc transporter atp-binding protein
BV504_RS18750	COG0765	amino acid transport
BV504_RS18755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BV504_RS18760	COG0316	Belongs to the HesB IscA family
BV504_RS18765	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BV504_RS18770	COG0038	chloride channel
BV504_RS18775	COG1981	membrane
BV504_RS18780	COG0351	phosphomethylpyrimidine kinase
BV504_RS18785	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BV504_RS18830	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BV504_RS18835	COG2885	chlorophyll binding
BV504_RS18840	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BV504_RS18845	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BV504_RS18850	COG0706	membrane insertase activity
BV504_RS18855	COG0594	ribonuclease P activity
BV504_RS18860	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BV504_RS18865	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BV504_RS18875	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BV504_RS18885	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BV504_RS18895	COG0751	glycine-tRNA ligase activity
BV504_RS18900	COG0752	glycyl-tRNA synthetase alpha subunit
BV504_RS18905	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BV504_RS18915	COG1368	sulfuric ester hydrolase activity
BV504_RS18920	COG2826	transposase and inactivated derivatives, IS30 family
BV504_RS18935	COG0463	Glycosyl transferase, family 2
BV504_RS18940	COG0859	PFAM glycosyl transferase family 9
BV504_RS18950	COG3642	lipopolysaccharide core region biosynthetic process
BV504_RS18960	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BV504_RS18960	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BV504_RS18965	COG1519	Transferase
BV504_RS18970	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BV504_RS18975	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BV504_RS18980	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BV504_RS19000	COG0006	proline dipeptidase activity
BV504_RS19005	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BV504_RS19010	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BV504_RS19015	COG0793	Belongs to the peptidase S41A family
BV504_RS19020	COG4942	peptidase
BV504_RS19025	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BV504_RS19030	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BV504_RS19035	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BV504_RS19040	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BV504_RS19045	COG2996	Protein conserved in bacteria
BV504_RS19050	COG0189	ligase activity
BV504_RS19055	COG1678	Uncharacterized ACR, COG1678
BV504_RS19060	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BV504_RS19065	COG0540	Belongs to the ATCase OTCase family
BV504_RS19110	COG0023	Translation Initiation Factor
BV504_RS19115	COG0546	phosphoglycolate phosphatase activity
BV504_RS19125	COG0126	phosphoglycerate kinase activity
BV504_RS19130	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BV504_RS19135	COG1346	cytolysis
BV504_RS19145	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BV504_RS19150	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BV504_RS19155	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BV504_RS19185	COG0339	signal peptide processing
BV504_RS19190	COG0733	neurotransmitter:sodium symporter activity
BV504_RS19195	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BV504_RS19220	COG1304	FMN binding
BV504_RS19250	COG2747	anti-sigma28 factor FlgM
BV504_RS19265	COG1558	bacterial-type flagellum-dependent cell motility
BV504_RS19295	COG1706	bacterial-type flagellum-dependent cell motility
BV504_RS19300	COG3951	Flagellar rod assembly protein muramidase FlgJ
BV504_RS19300	COG1705	Flagellar rod assembly protein muramidase FlgJ
BV504_RS19305	COG1256	bacterial-type flagellum assembly
BV504_RS19335	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BV504_RS19355	COG2882	bacterial-type flagellum organization
BV504_RS19375	COG1766	The M ring may be actively involved in energy transduction
BV504_RS19385	COG1334	flagellar protein FlaG
BV504_RS19390	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BV504_RS19430	COG1360	Flagellar Motor Protein
BV504_RS19440	COG0835	chemotaxis
BV504_RS19445	COG0840	transmembrane signaling receptor activity
BV504_RS19450	COG0840	transmembrane signaling receptor activity
BV504_RS19450	COG0840	transmembrane signaling receptor activity
BV504_RS19455	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BV504_RS19460	COG2201	protein-glutamate methylesterase activity
BV504_RS19465	COG0840	transmembrane signaling receptor activity
BV504_RS19470	COG0745	RESPONSE REGULATOR receiver
BV504_RS19485	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BV504_RS19510	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BV504_RS19520	COG3706	GGDEF domain
BV504_RS19555	COG2814	Major facilitator Superfamily
BV504_RS19560	COG0629	single-stranded DNA binding
BV504_RS19580	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BV504_RS19595	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BV504_RS19610	COG0300	oxidoreductase activity
BV504_RS19630	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
BV504_RS19635	COG1090	epimerase
BV504_RS19640	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BV504_RS19645	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BV504_RS19655	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BV504_RS19685	COG0733	neurotransmitter:sodium symporter activity
BV504_RS19705	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BV504_RS19705	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BV504_RS19710	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BV504_RS19745	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BV504_RS19750	COG0081	regulation of translation
BV504_RS19755	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BV504_RS19760	COG0222	ribosome binding
BV504_RS19765	COG0085	RNA polymerase activity
BV504_RS19770	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BV504_RS19775	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BV504_RS19780	COG0049	tRNA binding
BV504_RS19785	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BV504_RS19790	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BV504_RS19795	COG0051	transcription antitermination factor activity, RNA binding
BV504_RS19800	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BV504_RS19805	COG0088	Forms part of the polypeptide exit tunnel
BV504_RS19810	COG0089	rRNA binding
BV504_RS19815	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BV504_RS19820	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BV504_RS19825	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BV504_RS19830	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BV504_RS19835	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BV504_RS19840	COG0255	Belongs to the universal ribosomal protein uL29 family
BV504_RS19845	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BV504_RS19850	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BV504_RS19855	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BV504_RS19860	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BV504_RS19865	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BV504_RS19870	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BV504_RS19875	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BV504_RS19880	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BV504_RS19885	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BV504_RS19890	COG1841	ribosomal large subunit assembly
BV504_RS19895	COG0200	Binds to the 23S rRNA
BV504_RS19905	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BV504_RS19910	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BV504_RS19915	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BV504_RS19920	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BV504_RS19925	COG0202	RNA polymerase activity
BV504_RS19930	COG0203	ribosomal protein L17
BV504_RS19935	COG1686	Belongs to the peptidase S11 family
BV504_RS19945	COG0826	peptidase U32
BV504_RS19950	COG3384	dioxygenase
BV504_RS19960	COG0583	DNA-binding transcription factor activity
BV504_RS19965	COG0352	thiamine-phosphate diphosphorylase activity
BV504_RS19970	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BV504_RS20005	COG0803	Belongs to the bacterial solute-binding protein 9 family
BV504_RS20015	COG1121	(ABC) transporter
BV504_RS20065	COG1518	maintenance of DNA repeat elements
BV504_RS20080	COG1012	belongs to the aldehyde dehydrogenase family
BV504_RS20095	COG1960	acyl-CoA dehydrogenase activity
BV504_RS20105	COG1960	acyl-CoA dehydrogenase activity
BV504_RS20110	COG1960	acyl-CoA dehydrogenase activity
BV504_RS20155	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BV504_RS20155	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BV504_RS20160	COG0318	PFAM AMP-dependent synthetase and ligase
BV504_RS20180	COG1028	Short-chain dehydrogenase reductase Sdr
BV504_RS20220	COG2204	response regulator
BV504_RS20270	COG0671	phosphoesterase, PA-phosphatase related
BV504_RS20285	COG4149	molybdate abc transporter
BV504_RS20290	COG1840	ABC-type Fe3 transport system, periplasmic component
BV504_RS20295	COG3842	ATPase activity
BV504_RS20305	COG0737	Belongs to the 5'-nucleotidase family
BV504_RS20310	COG5507	3-demethylubiquinone-9 3-methyltransferase
BV504_RS20315	COG3795	YCII-related domain
BV504_RS20325	COG0583	DNA-binding transcription factor activity
BV504_RS20330	COG0667	Aldo Keto reductase
BV504_RS20335	COG4941	Belongs to the sigma-70 factor family
BV504_RS20340	COG3842	ATPase activity
BV504_RS20350	COG1175	transmembrane transport
BV504_RS20415	COG0142	geranyltranstransferase activity
BV504_RS20420	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BV504_RS20425	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BV504_RS20430	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BV504_RS20435	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BV504_RS20450	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BV504_RS20465	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BV504_RS20470	COG3639	organic phosphonate transmembrane transporter activity
BV504_RS20485	COG0791	NLP P60 protein
BV504_RS20510	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BV504_RS20525	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BV504_RS20530	COG0601	transmembrane transport
BV504_RS20540	COG0546	phosphoglycolate phosphatase activity
BV504_RS20545	COG0583	DNA-binding transcription factor activity
BV504_RS20570	COG3443	Belongs to the bacterial solute-binding protein 9 family
BV504_RS20585	COG2249	NAD(P)H dehydrogenase (quinone) activity
BV504_RS20590	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
BV504_RS20600	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BV504_RS20605	COG2867	negative regulation of translational initiation
BV504_RS20610	COG2914	Belongs to the UPF0125 (RnfH) family
BV504_RS20615	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BV504_RS20635	COG0497	DNA recombination
BV504_RS20640	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BV504_RS20645	COG0443	Heat shock 70 kDa protein
BV504_RS20650	COG0484	heat shock protein binding
BV504_RS20670	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BV504_RS20675	COG0402	S-adenosylhomocysteine deaminase activity
BV504_RS20680	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BV504_RS20690	COG2252	PERMEase
BV504_RS20715	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BV504_RS20720	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BV504_RS20725	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BV504_RS20730	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BV504_RS20735	COG0149	triose-phosphate isomerase activity
BV504_RS20755	COG0779	Required for maturation of 30S ribosomal subunits
BV504_RS20760	COG0195	Participates in both transcription termination and antitermination
BV504_RS20765	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BV504_RS20770	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BV504_RS20775	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BV504_RS20780	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BV504_RS20785	COG1185	polyribonucleotide nucleotidyltransferase activity
BV504_RS20800	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BV504_RS20805	COG1131	(ABC) transporter
BV504_RS20810	COG0842	Transport permease protein
BV504_RS20835	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BV504_RS20860	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BV504_RS20875	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BV504_RS20895	COG1126	abc transporter atp-binding protein
BV504_RS20900	COG2391	methyltransferase activity
BV504_RS20905	COG0281	malic enzyme
BV504_RS20915	COG0492	ferredoxin-NADP+ reductase activity
BV504_RS20935	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BV504_RS20935	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BV504_RS20960	COG0028	Belongs to the TPP enzyme family
BV504_RS20965	COG0440	acetolactate synthase activity
BV504_RS20975	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BV504_RS20980	COG1183	phosphatidylcholine synthase activity
BV504_RS21000	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BV504_RS21010	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BV504_RS21015	COG0709	Synthesizes selenophosphate from selenide and ATP
BV504_RS21025	COG3068	Protein conserved in bacteria
BV504_RS21035	COG0107	imidazoleglycerol-phosphate synthase activity
BV504_RS21040	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BV504_RS21045	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BV504_RS21050	COG0131	Imidazoleglycerol-phosphate dehydratase
BV504_RS21070	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
BV504_RS21205	COG1598	PFAM Uncharacterised protein family UPF0150
BV504_RS21310	COG3772	lysozyme
BV504_RS21350	COG4695	Portal protein
BV504_RS21360	COG1360	Flagellar Motor Protein
BV504_RS21370	COG5285	phytanoyl-CoA dioxygenase
BV504_RS21375	COG0179	Fumarylacetoacetate (FAA) hydrolase
BV504_RS21380	COG1166	arginine decarboxylase activity
BV504_RS21395	COG1840	ABC-type Fe3 transport system, periplasmic component
BV504_RS21400	COG3842	ATPase activity
BV504_RS21410	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BV504_RS21420	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BV504_RS21425	COG1444	tRNA N-acetyltransferase activity
BV504_RS21430	COG2195	Cleaves the N-terminal amino acid of tripeptides
BV504_RS21435	COG0783	Belongs to the Dps family
BV504_RS21440	COG1929	Belongs to the glycerate kinase type-1 family
BV504_RS21485	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BV504_RS21495	COG1607	acyl-coa hydrolase
BV504_RS21500	COG2031	fatty acid transporter
BV504_RS21505	COG0534	Mate efflux family protein
BV504_RS21510	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BV504_RS21515	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BV504_RS21525	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BV504_RS21540	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BV504_RS21570	COG3577	Aspartyl protease
BV504_RS21580	COG0745	RESPONSE REGULATOR receiver
BV504_RS21585	COG2205	protein histidine kinase activity
BV504_RS21590	COG0583	DNA-binding transcription factor activity
BV504_RS21595	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BV504_RS21610	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
BV504_RS21620	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BV504_RS21625	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BV504_RS21630	COG0140	phosphoribosyl-ATP diphosphatase activity
BV504_RS21635	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BV504_RS21655	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BV504_RS21660	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BV504_RS21670	COG0018	arginyl-trna synthetase
BV504_RS21675	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BV504_RS21680	COG0254	rRNA binding
BV504_RS21685	COG0281	malic enzyme
BV504_RS21690	COG1946	Acyl-CoA thioesterase
BV504_RS21700	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BV504_RS21710	COG1024	Enoyl-CoA hydratase
BV504_RS21715	COG1061	Type III restriction enzyme res subunit
BV504_RS21720	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BV504_RS21725	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves