locus-tag	class	description
E8A47_RS00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
E8A47_RS00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
E8A47_RS00015	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
E8A47_RS00020	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E8A47_RS00025	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
E8A47_RS00030	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
E8A47_RS00035	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
E8A47_RS00040	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
E8A47_RS00045	ENOG4105XA0	heptosyltransferase ii
E8A47_RS00050	ENOG4107RES	phosphoglycerol transferase I
E8A47_RS00055	ENOG4108JMC	lipopolysaccharide core biosynthesis protein
E8A47_RS00060	ENOG4107TYR	Glycosyl Transferase
E8A47_RS00065	ENOG4106WTF	Glycosyl transferase, family 2
E8A47_RS00070	ENOG4105CG5	Glycosyl transferase (Group 1
E8A47_RS00075	ENOG4105X1N	Glycosyl transferase family 8
E8A47_RS00080	ENOG4105PF3	O-Antigen polymerase
E8A47_RS00095	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
E8A47_RS00100	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
E8A47_RS00105	ENOG4105E66	phosphoriboisomerase A
E8A47_RS00110	ENOG4105C7B	Threonine dehydratase
E8A47_RS00115	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
E8A47_RS00125	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
E8A47_RS00135	ENOG4107RAQ	aminopeptidase
E8A47_RS00145	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
E8A47_RS00150	ENOG4105CN1	protease
E8A47_RS00155	ENOG41063SB	peptidase
E8A47_RS00160	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
E8A47_RS00165	ENOG4107YZP	Rhodanese domain protein
E8A47_RS00170	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
E8A47_RS00175	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
E8A47_RS00185	ENOG4107RJ1	sodium solute
E8A47_RS00190	ENOG4105QNR	S1 RNA binding domain protein
E8A47_RS00195	ENOG4105D7Z	glutathione synthase
E8A47_RS00200	ENOG4108UJU	UPF0301 protein
E8A47_RS00205	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
E8A47_RS00210	ENOG4105CXT	aspartate transcarbamylase
E8A47_RS00240	ENOG4108ZJT	translation initiation factor, Sui1
E8A47_RS00245	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
E8A47_RS00260	ENOG4105D2N	Aldolase
E8A47_RS00265	ENOG4105BZA	Phosphoglycerate kinase
E8A47_RS00270	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
E8A47_RS00275	ENOG41067MG	lrgb family
E8A47_RS00285	ENOG4105CV1	Transketolase (EC 2.2.1.1)
E8A47_RS00290	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
E8A47_RS00295	ENOG410649J	Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction (By similarity)
E8A47_RS00305	ENOG4105SYT	Methylenetetrahydrofolate reductase
E8A47_RS00325	ENOG4105DGW	oligopeptidase A
E8A47_RS00330	ENOG4105C8J	)-transporter
E8A47_RS00335	ENOG4108Z0R	Transferase
E8A47_RS00345	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E8A47_RS00350	ENOG4105CQZ	Histidine kinase
E8A47_RS00360	ENOG4105DMF	Dehydrogenase
E8A47_RS00410	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
E8A47_RS00415	ENOG4108ZC9	flagellar basal-body rod protein flgc
E8A47_RS00420	ENOG4105W00	Flagellar hook capping protein
E8A47_RS00425	ENOG4105BZE	flagellar hook protein, FlgE
E8A47_RS00430	ENOG4108KPB	Flagellar basal-body rod protein FlgF
E8A47_RS00435	ENOG4105CGA	flagellar basal-body rod protein FlgG
E8A47_RS00445	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
E8A47_RS00450	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
E8A47_RS00455	ENOG4105E1Q	flagellar hook-associated protein
E8A47_RS00460	ENOG4105DTJ	flagellar hook-associated protein
E8A47_RS00465	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
E8A47_RS00470	ENOG4105VS8	Flagellar biosynthetic protein fliq
E8A47_RS00475	ENOG4105CN7	Flagellar biosynthetic protein FliP
E8A47_RS00480	ENOG4105K0P	flagellar biosynthesis protein
E8A47_RS00485	ENOG4105DD5	Flagellar motor switch protein
E8A47_RS00490	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
E8A47_RS00495	ENOG4107ZI8	flagellar basal body-associated protein flil
E8A47_RS00505	ENOG4105GSA	Flagellar export protein flij
E8A47_RS00510	ENOG4108JIR	Flagellum-specific ATP synthase
E8A47_RS00520	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
E8A47_RS00525	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
E8A47_RS00535	ENOG41063QE	flagellar protein FlaG
E8A47_RS00540	ENOG4106825	Type iv pilus assembly
E8A47_RS00545	ENOG4105MQ3	flagellar protein FliS
E8A47_RS00560	ENOG4105D00	flagellar biosynthetic protein flhB
E8A47_RS00565	ENOG4105GEH	Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity)
E8A47_RS00570	ENOG4106CIA	Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region
E8A47_RS00575	ENOG4107RD7	Flagellar Motor Protein, MotA
E8A47_RS00580	ENOG4105ER2	Ompa motb domain protein
E8A47_RS00585	ENOG4105CBS	Chea signal transduction histidine kinase
E8A47_RS00590	ENOG4108V3W	Chemotaxis protein, CheW
E8A47_RS00595	ENOG4105C8Q	Methyl-accepting chemotaxis
E8A47_RS00600	ENOG4105C8Q	Methyl-accepting chemotaxis
E8A47_RS00605	ENOG4105BZU	Histidine kinase
E8A47_RS00610	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
E8A47_RS00615	ENOG4105C8Q	Methyl-accepting chemotaxis
E8A47_RS00620	ENOG4108VYJ	response regulator receiver protein
E8A47_RS00625	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
E8A47_RS00630	ENOG4105D00	flagellar biosynthetic protein flhB
E8A47_RS00635	ENOG4105D7B	Flagellar biosynthesis protein flha
E8A47_RS00640	ENOG4105FZW	flagellar biosynthesis regulator FlhF
E8A47_RS00655	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E8A47_RS00660	ENOG4107R0U	MotA TolQ exbB proton channel
E8A47_RS00665	ENOG4106VK6	Flagellar motor protein
E8A47_RS00690	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
E8A47_RS00695	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
E8A47_RS00700	ENOG4107RDB	Major Facilitator
E8A47_RS00705	ENOG4108UUM	single-stranded DNA-binding protein
E8A47_RS00735	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
E8A47_RS00740	ENOG4105BZU	Histidine kinase
E8A47_RS00765	ENOG4107FW0	short-chain dehydrogenase reductase
E8A47_RS00775	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
E8A47_RS00785	ENOG4105ECP	epimerase
E8A47_RS00790	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
E8A47_RS00795	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E8A47_RS00810	ENOG4107R3N	Filamentation induced by cAMP protein fic
E8A47_RS00820	ENOG4105C32	Amino acid ABC transporter (Permease)
E8A47_RS00825	ENOG4108IV0	ABC, transporter
E8A47_RS00830	ENOG4105C0Z	ABC transporter
E8A47_RS00835	ENOG4105C8J	)-transporter
E8A47_RS00840	ENOG4105CI3	gtp-binding protein typa
E8A47_RS00845	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
E8A47_RS00850	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
E8A47_RS00875	ENOG4105PM1	preprotein translocase subunit SecE
E8A47_RS00880	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
E8A47_RS00885	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
E8A47_RS00890	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
E8A47_RS00895	ENOG4108VZM	50s ribosomal protein L10
E8A47_RS00900	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
E8A47_RS00905	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
E8A47_RS00910	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
E8A47_RS00915	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
E8A47_RS00920	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
E8A47_RS00930	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
E8A47_RS00935	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
E8A47_RS00940	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
E8A47_RS00945	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
E8A47_RS00950	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
E8A47_RS00955	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
E8A47_RS00960	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
E8A47_RS00965	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
E8A47_RS00970	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
E8A47_RS00975	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
E8A47_RS00980	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
E8A47_RS00985	ENOG41083MP	50s ribosomal protein l29
E8A47_RS00990	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
E8A47_RS00995	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
E8A47_RS01000	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
E8A47_RS01005	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
E8A47_RS01010	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
E8A47_RS01015	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
E8A47_RS01020	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
E8A47_RS01025	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
E8A47_RS01030	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
E8A47_RS01035	ENOG4105VPB	50S ribosomal protein L30
E8A47_RS01040	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
E8A47_RS01045	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
E8A47_RS01050	ENOG41067V7	50S ribosomal protein L36
E8A47_RS01055	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
E8A47_RS01060	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
E8A47_RS01065	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
E8A47_RS01070	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
E8A47_RS01075	ENOG4108ZT0	50S ribosomal protein l17
E8A47_RS01080	ENOG4105DZ1	carboxypeptidase
E8A47_RS01090	ENOG4105CFP	Peptidase U32
E8A47_RS01095	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
E8A47_RS01105	ENOG4105CC0	LysR family Transcriptional regulator
E8A47_RS01110	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
E8A47_RS01145	ENOG4105ETT	transcriptional Regulator, LysR family
E8A47_RS01150	ENOG4105DSE	periplasmic solute binding protein
E8A47_RS01155	ENOG4105CC5	ABC transporter
E8A47_RS01160	ENOG4105DIK	(ABC) transporter
E8A47_RS01195	ENOG4108Y1S	CRISPR-associated protein, Csy4 family
E8A47_RS01215	ENOG4105D0M	Protease HtpX homolog
E8A47_RS01240	ENOG4105C5F	glutamine synthetase
E8A47_RS01250	ENOG4105CUX	Signal transduction histidine kinase
E8A47_RS01255	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E8A47_RS01270	ENOG4106BSU	Entericidin B
E8A47_RS01275	ENOG410841Q	phosphoesterase PA-phosphatase related protein
E8A47_RS01290	ENOG4105CGH	5'-nucleotidase
E8A47_RS01295	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
E8A47_RS01300	ENOG4105GRZ	Ycii-related protein
E8A47_RS01310	ENOG410642W	LysR family Transcriptional regulator
E8A47_RS01315	ENOG4105CPC	Aldo Keto reductase
E8A47_RS01320	ENOG4105CHP	RNA polymerase
E8A47_RS01330	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
E8A47_RS01340	ENOG4105BZ7	extracellular solute-binding protein family 1
E8A47_RS01345	ENOG4105CWC	Acetylornithine deacetylase
E8A47_RS01355	ENOG4105K5B	UPF0225 protein
E8A47_RS01365	ENOG41067B5	Histone deacetylase superfamily protein
E8A47_RS01375	ENOG4108JQ6	ABC transporter
E8A47_RS01380	ENOG4105DEF	Extracellular solute-binding protein, family 5
E8A47_RS01385	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
E8A47_RS01390	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
E8A47_RS01400	ENOG4105F2V	VRR-NUC domain-containing protein
E8A47_RS01420	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
E8A47_RS01425	ENOG4105C2D	reductase
E8A47_RS01435	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
E8A47_RS01465	ENOG4105C84	Histidine ammonia-lyase
E8A47_RS01520	ENOG4107RCC	Major Facilitator Superfamily
E8A47_RS01530	ENOG41071TK	Uncharacterised protein family (UPF0150)
E8A47_RS01555	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
E8A47_RS01595	ENOG4105KT5	UmuD protein
E8A47_RS01640	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
E8A47_RS01660	ENOG4105EAH	synthase
E8A47_RS01665	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
E8A47_RS01670	ENOG4105K46	50S ribosomal protein l27
E8A47_RS01675	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
E8A47_RS01680	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
E8A47_RS01700	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
E8A47_RS01715	ENOG4105BZU	Histidine kinase
E8A47_RS01725	ENOG4105D5T	phosphonate abc transporter
E8A47_RS01730	ENOG4105S7S	phosphonate abc transporter
E8A47_RS01745	ENOG4105K4H	Nlp p60 protein
E8A47_RS01750	ENOG4108N3W	hemolysin secretion protein
E8A47_RS01755	ENOG4105BZU	Histidine kinase
E8A47_RS01785	ENOG4105BZU	Histidine kinase
E8A47_RS01790	ENOG4105DN9	Na H antiporter
E8A47_RS01815	ENOG4105VEQ	Cold shock protein
E8A47_RS01820	ENOG4108MEK	Metal-binding protein YodA
E8A47_RS01835	ENOG4105CUB	amino acid
E8A47_RS01865	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
E8A47_RS01890	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
E8A47_RS01895	ENOG4108Z1B	Cyclase dehydrase
E8A47_RS01900	ENOG4105VDB	UPF0125 protein
E8A47_RS01905	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
E8A47_RS01910	ENOG41090R7	Ferric uptake
E8A47_RS01915	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
E8A47_RS01920	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
E8A47_RS01925	ENOG4105CFG	Acts as a chaperone (By similarity)
E8A47_RS01930	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
E8A47_RS01945	ENOG4105E0A	ABC, transporter
E8A47_RS01950	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
E8A47_RS01965	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
E8A47_RS01980	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
E8A47_RS01985	ENOG4105HBR	Rna-binding protein
E8A47_RS01990	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
E8A47_RS01995	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
E8A47_RS02000	ENOG4105EEI	dihydropteroate synthase
E8A47_RS02005	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
E8A47_RS02010	ENOG4105CP7	Triose-phosphate isomerase
E8A47_RS02015	ENOG4105NTZ	Preprotein translocase subunit SecG
E8A47_RS02030	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
E8A47_RS02035	ENOG4105CHV	Transcription elongation factor NusA
E8A47_RS02040	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
E8A47_RS02045	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
E8A47_RS02050	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
E8A47_RS02055	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
E8A47_RS02060	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
E8A47_RS02065	ENOG4107RTG	Major Facilitator superfamily
E8A47_RS02070	ENOG4105ETT	transcriptional Regulator, LysR family
E8A47_RS02075	ENOG4105CM2	brancheD-chain amino acid aminotransferase
E8A47_RS02090	ENOG410846T	CoA-transferase family III
E8A47_RS02100	ENOG4105CHU	acetyl-coa acetyltransferase
E8A47_RS02105	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
E8A47_RS02110	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
E8A47_RS02115	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
E8A47_RS02125	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
E8A47_RS02130	ENOG4105DJ0	Poly(A) Polymerase
E8A47_RS02135	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E8A47_RS02140	ENOG4105BZU	Histidine kinase
E8A47_RS02145	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
E8A47_RS02160	ENOG4105PW4	Sugar fermentation stimulation protein homolog
E8A47_RS02170	ENOG4105DWV	Homoserine O-trans-acetylase
E8A47_RS02180	ENOG4108VIA	integral membrane protein
E8A47_RS02185	ENOG4105II7	pyrroline-5-carboxylate reductase
E8A47_RS02190	ENOG4105DFA	alanine racemase domain protein
E8A47_RS02195	ENOG4105CZX	twitching motility protein
E8A47_RS02200	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
E8A47_RS02205	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
E8A47_RS02235	ENOG4105D1Q	UPF0246 protein
E8A47_RS02240	ENOG4105CPC	Aldo Keto reductase
E8A47_RS02255	ENOG4108URH	decarboxylase
E8A47_RS02285	ENOG4105C87	Aminotransferase class I and II
E8A47_RS02300	ENOG4105CC0	LysR family Transcriptional regulator
E8A47_RS02310	ENOG4105CHR	reductase
E8A47_RS02320	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
E8A47_RS02325	ENOG4107QMS	site-determining protein
E8A47_RS02330	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
E8A47_RS02335	ENOG4105CJB	Exodeoxyribonuclease I
E8A47_RS02340	ENOG4107QXK	peptidase
E8A47_RS02360	ENOG4108JU6	CBS domain protein
E8A47_RS02365	ENOG4106KVJ	cytochrome C assembly protein
E8A47_RS02370	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
E8A47_RS02375	ENOG4105K5M	30s ribosomal protein S16
E8A47_RS02380	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
E8A47_RS02385	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
E8A47_RS02390	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
E8A47_RS02395	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
E8A47_RS02400	ENOG4105T95	Thiol disulfide interChange protein
E8A47_RS02405	ENOG4105D6E	homoserine dehydrogenase
E8A47_RS02410	ENOG4105D98	threonine synthase
E8A47_RS02415	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
E8A47_RS02425	ENOG4105C59	p-type ATPase
E8A47_RS02430	ENOG4105W1Y	Transcriptional regulator
E8A47_RS02445	ENOG4105CRK	lysyL-tRNA synthetase
E8A47_RS02455	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
E8A47_RS02460	ENOG4105M85	Bola protein
E8A47_RS02470	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
E8A47_RS02475	ENOG4105N4M	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
E8A47_RS02480	ENOG4106H78	methyltransferase
E8A47_RS02485	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
E8A47_RS02490	ENOG4105CAK	Cell division ATP-binding protein ftsE
E8A47_RS02495	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
E8A47_RS02500	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E8A47_RS02505	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
E8A47_RS02510	ENOG4105CAS	nag kinase
E8A47_RS02515	ENOG4107QKV	phosphomannomutase
E8A47_RS02520	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
E8A47_RS02525	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
E8A47_RS02530	ENOG4105W5Q	DNA repair protein (RadC
E8A47_RS02535	ENOG4105KDC	50s ribosomal protein l28
E8A47_RS02540	ENOG4105W0E	50S ribosomal protein L33
E8A47_RS02545	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
E8A47_RS02550	ENOG4105DR4	Methyltransferase
E8A47_RS02560	ENOG4105DCF	alanine dehydrogenase
E8A47_RS02570	ENOG4105VEQ	Cold shock protein
E8A47_RS02580	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
E8A47_RS02595	ENOG4105CHM	Aminotransferase
E8A47_RS02605	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
E8A47_RS02615	ENOG4105CE9	30S ribosomal protein S2
E8A47_RS02620	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
E8A47_RS02625	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
E8A47_RS02630	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
E8A47_RS02635	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
E8A47_RS02640	ENOG4105KNE	Phosphatidate cytidylyltransferase
E8A47_RS02645	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
E8A47_RS02650	ENOG4105DZP	Membrane-associated zinc metalloprotease
E8A47_RS02665	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
E8A47_RS02670	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
E8A47_RS02675	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
E8A47_RS02680	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
E8A47_RS02685	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
E8A47_RS02690	ENOG4105C0B	DNA polymerase III (alpha subunit)
E8A47_RS02695	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
E8A47_RS02700	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
E8A47_RS02705	ENOG4105C9X	ppx gppa phosphatase
E8A47_RS02710	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
E8A47_RS02715	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
E8A47_RS02720	ENOG4107QK7	reductase
E8A47_RS02725	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
E8A47_RS02740	ENOG4105S2T	inner membrane protein YbcI
E8A47_RS02745	ENOG4108UYE	Lactoylglutathione lyase
E8A47_RS02760	ENOG4105BZU	Histidine kinase
E8A47_RS02770	ENOG4107QN2	dihydrolipoyl dehydrogenase
E8A47_RS02785	ENOG4108VGW	abc transporter atp-binding protein
E8A47_RS02790	ENOG4105CXZ	ABC transporter, permease
E8A47_RS02795	ENOG4105VNH	ABC transporter solute-binding protein
E8A47_RS02825	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
E8A47_RS02850	ENOG4105CM2	brancheD-chain amino acid aminotransferase
E8A47_RS02855	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
E8A47_RS02860	ENOG4108M8S	permease YjgP YjgQ family protein
E8A47_RS02865	ENOG4108K5H	permease YjgP YjgQ family protein
E8A47_RS02880	ENOG4108UQY	Iron-storage protein
E8A47_RS02895	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
E8A47_RS02910	ENOG4108JQ7	(ABC) transporter
E8A47_RS02915	ENOG4105C3U	ABC transporter
E8A47_RS02920	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
E8A47_RS02960	ENOG4105DR9	pseudouridine synthase
E8A47_RS02965	ENOG4105CUZ	uba thif-type nad fad binding protein
E8A47_RS02975	ENOG4105C9U	ATP-dependent DNA helicase RecQ
E8A47_RS02980	ENOG4105CFC	Transporter
E8A47_RS02985	ENOG4105CH2	amidohydrolase
E8A47_RS03000	ENOG4108D1Y	Polypeptide-transport-associated domain protein, ShlB-type
E8A47_RS03030	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
E8A47_RS03040	ENOG4105BZU	Histidine kinase
E8A47_RS03050	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
E8A47_RS03055	ENOG4108K3Z	AraC family transcriptional regulator
E8A47_RS03060	ENOG4105CPD	ethanolamine ammonia-lyase
E8A47_RS03065	ENOG4107FQ9	ethanolamine ammonia-lyase
E8A47_RS03070	ENOG4105CUB	amino acid
E8A47_RS03080	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
E8A47_RS03085	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
E8A47_RS03095	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
E8A47_RS03100	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
E8A47_RS03105	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
E8A47_RS03110	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
E8A47_RS03115	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
E8A47_RS03120	ENOG4106IUH	DTW domain containing protein
E8A47_RS03130	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
E8A47_RS03135	ENOG4105C1A	potassium transporter peripheral membrane
E8A47_RS03140	ENOG4105WKW	Pfam:DUF1458
E8A47_RS03145	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
E8A47_RS03150	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
E8A47_RS03155	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
E8A47_RS03165	ENOG4105C79	DNA protecting protein DprA
E8A47_RS03170	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
E8A47_RS03180	ENOG4105E2X	shikimate dehydrogenase
E8A47_RS03205	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
E8A47_RS03210	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
E8A47_RS03215	ENOG4105N21	Membrane
E8A47_RS03220	ENOG4105CUT	histidyl-tRNA synthetase
E8A47_RS03225	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
E8A47_RS03240	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
E8A47_RS03245	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
E8A47_RS03250	ENOG4108Z4V	iron-sulfur cluster assembly
E8A47_RS03255	ENOG4105C3J	Cysteine desulfurase
E8A47_RS03260	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
E8A47_RS03275	ENOG4105ECY	inositol monophosphatase
E8A47_RS03280	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
E8A47_RS03285	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
E8A47_RS03290	ENOG4105VIE	preprotein translocase, subunit YajC
E8A47_RS03295	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
E8A47_RS03300	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
E8A47_RS03310	ENOG4105BZF	Glycosyl transferase (Group 1
E8A47_RS03320	ENOG4105M4H	endoribonuclease L-psp
E8A47_RS03325	ENOG4105CIF	Ornithine Cyclodeaminase
E8A47_RS03340	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E8A47_RS03350	ENOG4105DGU	Histone deacetylase
E8A47_RS03355	ENOG4105CM2	brancheD-chain amino acid aminotransferase
E8A47_RS03360	ENOG4105CIH	Imidazole acetol-phosphate transaminase
E8A47_RS03365	ENOG4105CQB	FAD linked oxidase domain protein
E8A47_RS03375	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
E8A47_RS03385	ENOG4105DEF	Extracellular solute-binding protein, family 5
E8A47_RS03410	ENOG4105H1N	peptidase, M24
E8A47_RS03485	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
E8A47_RS03495	ENOG41082AG	Plasmid maintenance system antidote protein
E8A47_RS03515	ENOG4105DWV	Homoserine O-trans-acetylase
E8A47_RS03520	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
E8A47_RS03525	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
E8A47_RS03530	ENOG4105ECQ	AraC Family Transcriptional Regulator
E8A47_RS03535	ENOG4105CHR	reductase
E8A47_RS03540	ENOG4105CNG	UPF0061 protein
E8A47_RS03545	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
E8A47_RS03570	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E8A47_RS03575	ENOG4108JPW	Aminotransferase
E8A47_RS03580	ENOG4105BZU	Histidine kinase
E8A47_RS03585	ENOG4105BZU	Histidine kinase
E8A47_RS03590	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
E8A47_RS03595	ENOG4105C1G	acyl-Coa dehydrogenase
E8A47_RS03600	ENOG4108PVQ	transcriptional regulator
E8A47_RS03620	ENOG4108JQC	penicillin-binding protein 1A
E8A47_RS03645	ENOG4105E4G	Type IV pilus
E8A47_RS03650	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
E8A47_RS03655	ENOG4105D49	3-dehydroquinate synthase
E8A47_RS03660	ENOG4105CBC	glutamate synthase
E8A47_RS03665	ENOG4105BZ8	glutamate synthase
E8A47_RS03670	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
E8A47_RS03675	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
E8A47_RS03680	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
E8A47_RS03685	ENOG4108Z4U	Ferredoxin
E8A47_RS03690	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
E8A47_RS03695	ENOG4107TH8	cina domain protein
E8A47_RS03700	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
E8A47_RS03705	ENOG4105Y3E	Modulates RecA activity (By similarity)
E8A47_RS03710	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
E8A47_RS03715	ENOG4105CFH	Aspartokinase
E8A47_RS03720	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
E8A47_RS03740	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
E8A47_RS03750	ENOG4107QSA	Oxaloacetate decarboxylase
E8A47_RS03755	ENOG4105D9Q	decarboxylase (Beta subunit)
E8A47_RS03760	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
E8A47_RS03770	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
E8A47_RS03775	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
E8A47_RS03780	ENOG41060IM	Heme exporter protein
E8A47_RS03785	ENOG41067VX	Heme exporter protein
E8A47_RS03790	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
E8A47_RS03795	ENOG4105DA4	cytochrome c-type biogenesis protein
E8A47_RS03800	ENOG4107QX9	Thiol disulfide interChange protein
E8A47_RS03805	ENOG4105KWW	Biogenesis protein
E8A47_RS03810	ENOG4108M1T	Cytochrome c-type biogenesis protein
E8A47_RS03815	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
E8A47_RS03820	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
E8A47_RS03830	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
E8A47_RS03880	ENOG4105DHQ	Histidine kinase
E8A47_RS03885	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
E8A47_RS03895	ENOG41080IJ	Diacylglycerol kinase
E8A47_RS03905	ENOG4105DIJ	Phosphoethanolamine transferase
E8A47_RS03920	ENOG4105F2I	Transposase
E8A47_RS03935	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
E8A47_RS03940	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
E8A47_RS03950	ENOG4105C59	p-type ATPase
E8A47_RS03955	ENOG4105W1Y	Transcriptional regulator
E8A47_RS03975	ENOG4105W1Y	Transcriptional regulator
E8A47_RS03980	ENOG4108K5P	(LipO)protein
E8A47_RS03985	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
E8A47_RS04020	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
E8A47_RS04030	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
E8A47_RS04035	ENOG4105K9H	YciI-like protein
E8A47_RS04040	ENOG4105DB7	PHP domain protein
E8A47_RS04045	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
E8A47_RS04055	ENOG4105EYW	Ion transport protein
E8A47_RS04065	ENOG4107IX6	phosphate transport regulator
E8A47_RS04070	ENOG4105CJ3	phosphate transporter
E8A47_RS04075	ENOG4108EKC	n-acetylglutamate synthase
E8A47_RS04085	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
E8A47_RS04105	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
E8A47_RS04120	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
E8A47_RS04140	ENOG4105F04	LysR family Transcriptional regulator
E8A47_RS04150	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
E8A47_RS04155	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
E8A47_RS04180	ENOG4105CKW	Inner membrane protein yedI
E8A47_RS04190	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
E8A47_RS04195	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
E8A47_RS04200	ENOG4105GZI	Transcriptional regulator
E8A47_RS04210	ENOG4108I0N	Transporter, RarD family, DMT superfamily protein
E8A47_RS04215	ENOG4105ETT	transcriptional Regulator, LysR family
E8A47_RS04275	ENOG4105CR8	Transcriptional regulator
E8A47_RS04290	ENOG4105CHR	reductase
E8A47_RS04295	ENOG4105CKW	Inner membrane protein yedI
E8A47_RS04315	ENOG4105DZG	Dehydrogenase
E8A47_RS04320	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
E8A47_RS04325	ENOG4105C5Q	Transcriptional regulator
E8A47_RS04335	ENOG4105JAB	phenazine biosynthesis protein, phzf family
E8A47_RS04350	ENOG4105KVH	Transcriptional regulator
E8A47_RS04360	ENOG410645S	MarR family Transcriptional regulator
E8A47_RS04370	ENOG4105C1Q	protoporphyrinogen oxidase
E8A47_RS04380	ENOG4105BZU	Histidine kinase
E8A47_RS04385	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
E8A47_RS04395	ENOG4105BZS	acriflavin resistance protein
E8A47_RS04405	ENOG4105DND	Transcriptional regulator
E8A47_RS04410	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
E8A47_RS04420	ENOG4105DC7	peptidase M24
E8A47_RS04430	ENOG4107RSM	transcriptional regulator
E8A47_RS04440	ENOG4105C2C	drug resistance transporter, Bcr CflA
E8A47_RS04465	ENOG4105E0K	tonB-dependent siderophore receptor
E8A47_RS04475	ENOG4105JAB	phenazine biosynthesis protein, phzf family
E8A47_RS04495	ENOG4108XTP	Transcriptional regulator
E8A47_RS04520	ENOG4105DJ2	Major Facilitator Superfamily
E8A47_RS04530	ENOG4105BZS	acriflavin resistance protein
E8A47_RS04560	ENOG4105DHQ	Histidine kinase
E8A47_RS04590	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
E8A47_RS04595	ENOG4105E68	Sulfatase
E8A47_RS04600	ENOG4108UW5	maltose o-acetyltransferase
E8A47_RS04625	ENOG4105E0F	Histidine kinase
E8A47_RS04630	ENOG4105MGM	doxx family
E8A47_RS04635	ENOG4105CF7	AraC family transcriptional regulator
E8A47_RS04655	ENOG4108VHC	Short-chain dehydrogenase reductase Sdr
E8A47_RS04660	ENOG4108UQ8	endoribonuclease L-psp
E8A47_RS04675	ENOG4105Y49	secretion protein, HlyD family
E8A47_RS04695	ENOG4105F27	Major Facilitator
E8A47_RS04705	ENOG4105CBN	LysR family transcriptional regulator
E8A47_RS04710	ENOG4105CVN	desaturase
E8A47_RS04725	ENOG4105HEI	LysR family (Transcriptional regulator
E8A47_RS04730	ENOG4105NF4	modulator of drug activity
E8A47_RS04735	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
E8A47_RS04740	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
E8A47_RS04745	ENOG4105CBC	glutamate synthase
E8A47_RS04770	ENOG4108Z3N	Transcriptional regulator
E8A47_RS04775	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
E8A47_RS04790	ENOG4105CEY	Amp-dependent synthetase and ligase
E8A47_RS04810	ENOG4105DHI	Methyltransferase
E8A47_RS04815	ENOG4105VEQ	Cold shock protein
E8A47_RS04820	ENOG4105EMU	Dehydrogenase
E8A47_RS04825	ENOG4105CF7	AraC family transcriptional regulator
E8A47_RS04840	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E8A47_RS04850	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
E8A47_RS04855	ENOG4105ECQ	AraC Family Transcriptional Regulator
E8A47_RS04865	ENOG4105CHB	tonB-dependent Receptor
E8A47_RS04870	ENOG4105DZG	Dehydrogenase
E8A47_RS04875	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
E8A47_RS04880	ENOG4105K6T	rare lipoprotein A
E8A47_RS04905	ENOG4105BZU	Histidine kinase
E8A47_RS04910	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
E8A47_RS04935	ENOG4105IBP	Cyclic peptide transporter
E8A47_RS04945	ENOG4105E0A	ABC, transporter
E8A47_RS04950	ENOG4105ECY	inositol monophosphatase
E8A47_RS04965	ENOG4108KPJ	rna polymerase sigma factor
E8A47_RS05010	ENOG4105J76	Periplasmic binding protein
E8A47_RS05015	ENOG4105E0K	tonB-dependent siderophore receptor
E8A47_RS05025	ENOG4105F1Y	L-lysine 6-monooxygenase (NADPH)
E8A47_RS05030	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
E8A47_RS05035	ENOG4105F1Y	L-lysine 6-monooxygenase (NADPH)
E8A47_RS05045	ENOG4105IBP	Cyclic peptide transporter
E8A47_RS05055	ENOG41082AG	Plasmid maintenance system antidote protein
E8A47_RS05080	ENOG4105E7D	Protein of unknown function (DUF3375)
E8A47_RS05095	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
E8A47_RS05100	ENOG4105IBP	Cyclic peptide transporter
E8A47_RS05135	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
E8A47_RS05145	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E8A47_RS05150	ENOG4108JQ1	Dehydrogenase
E8A47_RS05155	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
E8A47_RS05175	ENOG4105E0K	tonB-dependent siderophore receptor
E8A47_RS05180	ENOG4105J76	Periplasmic binding protein
E8A47_RS05185	ENOG4108SF5	RNA Polymerase
E8A47_RS05190	ENOG4108S3W	Anti-feci sigma factor, fecr
E8A47_RS05200	ENOG4105J76	Periplasmic binding protein
E8A47_RS05210	ENOG4105D2H	Uronic isomerase
E8A47_RS05215	ENOG4105CJQ	hydrolase, family 31
E8A47_RS05220	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E8A47_RS05230	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
E8A47_RS05240	ENOG4107YCY	Transcriptional regulator
E8A47_RS05245	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
E8A47_RS05250	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
E8A47_RS05255	ENOG4105C5W	Aldolase
E8A47_RS05265	ENOG4108HK0	-acetyltransferase
E8A47_RS05270	ENOG4108K0D	peptidase, M48
E8A47_RS05280	ENOG4105EQX	glucarate dehydratase
E8A47_RS05325	ENOG4105CTX	dehydratase
E8A47_RS05335	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
E8A47_RS05350	ENOG4105C7K	acetolactate synthase
E8A47_RS05360	ENOG4105JXH	GntR family transcriptional regulator
E8A47_RS05370	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
E8A47_RS05375	ENOG4105C54	Major Facilitator superfamily
E8A47_RS05385	ENOG4105CS6	Rhs element vgr protein
E8A47_RS05425	ENOG4107QZF	nitrite reductase NADPH large subunit
E8A47_RS05430	ENOG4108IFG	nitrite reductase, (NAD(P)H)
E8A47_RS05440	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
E8A47_RS05455	ENOG4105CV8	reductase
E8A47_RS05470	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
E8A47_RS05480	ENOG4105BZU	Histidine kinase
E8A47_RS05490	ENOG4105C8Q	Methyl-accepting chemotaxis
E8A47_RS05500	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
E8A47_RS05520	ENOG4105FGV	Chromate
E8A47_RS05525	ENOG4105FGV	Chromate
E8A47_RS05540	ENOG4105BZU	Histidine kinase
E8A47_RS05545	ENOG4105C8Q	Methyl-accepting chemotaxis
E8A47_RS05555	ENOG4105DEN	Luciferase family
E8A47_RS05560	ENOG4105EMU	Dehydrogenase
E8A47_RS05590	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
E8A47_RS05595	ENOG4105DR5	peptidase
E8A47_RS05600	ENOG4105C5Q	Transcriptional regulator
E8A47_RS05605	ENOG4105CHF	Glutathione S-transferase
E8A47_RS05630	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
E8A47_RS05635	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
E8A47_RS05640	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
E8A47_RS05645	ENOG4108Z86	Glutamine amidotransferase
E8A47_RS05655	ENOG4105D8X	mechanosensitive ion channel
E8A47_RS05665	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
E8A47_RS05675	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
E8A47_RS05690	ENOG4107TYG	Oxidoreductase domain-containing protein
E8A47_RS05695	ENOG4105ETE	Transcriptional regulator (LacI family
E8A47_RS05705	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
E8A47_RS05720	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
E8A47_RS05725	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
E8A47_RS05730	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
E8A47_RS05735	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
E8A47_RS05740	ENOG4105D9N	nucleoside
E8A47_RS05745	ENOG4108NFH	Sugar hydrolase
E8A47_RS05750	ENOG4107FB0	transcriptional regulator DeoR family
E8A47_RS05755	ENOG4105E2S	oxidase) subunit II
E8A47_RS05760	ENOG4105BZ9	Cytochrome C oxidase, subunit I
E8A47_RS05765	ENOG4105CCU	oxidase (Subunit III)
E8A47_RS05770	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
E8A47_RS05775	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
E8A47_RS05780	ENOG4108DNC	Involved in acetate metabolism (By similarity)
E8A47_RS05785	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
E8A47_RS05800	ENOG4105Y49	secretion protein, HlyD family
E8A47_RS05815	ENOG4107QPK	)-transporter
E8A47_RS05820	ENOG4105CPQ	Dehydrogenase
E8A47_RS05835	ENOG41081QV	Universal stress protein
E8A47_RS05845	ENOG4105CHR	reductase
E8A47_RS05855	ENOG4105CMI	transporter
E8A47_RS05860	ENOG4105CJ1	ABC, transporter
E8A47_RS05865	ENOG4105D0S	secretion protein (HlyD
E8A47_RS05875	ENOG4105ETU	transcriptional activator (TenA
E8A47_RS05880	ENOG4105KHC	sulfurtransferase
E8A47_RS05915	ENOG4105CV8	reductase
E8A47_RS05930	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
E8A47_RS05955	ENOG4108MAJ	Membrane
E8A47_RS05975	ENOG4106JUT	Streptomycin 3''-adenylyltransferase
E8A47_RS05985	ENOG4105D9U	N-acetyltransferase
E8A47_RS05990	ENOG4105EJC	lysr family transcriptional regulator
E8A47_RS05995	ENOG4105F27	Major Facilitator
E8A47_RS06000	ENOG4105CPC	Aldo Keto reductase
E8A47_RS06015	ENOG4105DKW	ABC transporter
E8A47_RS06020	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
E8A47_RS06025	ENOG4105EMY	transcriptional regulator
E8A47_RS06030	ENOG4105DUM	transcriptional regulator, lysR family
E8A47_RS06050	ENOG4105HP8	regulator of competence-specific genes
E8A47_RS06065	ENOG4107U5X	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
E8A47_RS06085	ENOG4107RTG	Major Facilitator superfamily
E8A47_RS06100	ENOG4105C57	major facilitator superfamily
E8A47_RS06105	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
E8A47_RS06115	ENOG4108KPJ	rna polymerase sigma factor
E8A47_RS06120	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
E8A47_RS06130	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
E8A47_RS06150	ENOG4108Y50	Glutathione-dependent formaldehyde-activating Gfa
E8A47_RS06180	ENOG4105JNK	Glycosyl transferase (Group 1
E8A47_RS06190	ENOG4107QJN	gtp cyclohydrolase ii
E8A47_RS06205	ENOG4105DJ9	glucan biosynthesis protein
E8A47_RS06215	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
E8A47_RS06235	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
E8A47_RS06250	ENOG4105CSU	acyl-Coa dehydrogenase
E8A47_RS06255	ENOG4105CEY	Amp-dependent synthetase and ligase
E8A47_RS06260	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
E8A47_RS06265	ENOG4105E39	Enoyl-CoA hydratase
E8A47_RS06275	ENOG4108TGY	Glutathione S-transferase
E8A47_RS06280	ENOG4108VWS	Yaeq family
E8A47_RS06300	ENOG4105CYM	Glutathione S-transferase
E8A47_RS06310	ENOG4108ZHJ	Organic hydroperoxide resistance protein
E8A47_RS06315	ENOG4105K56	Transcriptional regulator
E8A47_RS06320	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
E8A47_RS06330	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E8A47_RS06335	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
E8A47_RS06340	ENOG4105DIQ	Transcriptional regulator
E8A47_RS06350	ENOG4108TVT	permease
E8A47_RS06355	ENOG4108Z9K	Osmotically inducible protein
E8A47_RS06365	ENOG4108PXI	ErfK YbiS YcfS YnhG
E8A47_RS06390	ENOG4105DKT	Transcriptional regulator
E8A47_RS06400	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
E8A47_RS06410	ENOG4108IJ9	(ABC) transporter
E8A47_RS06420	ENOG4105CHR	reductase
E8A47_RS06425	ENOG4107Z1W	Fructose transport system kinase
E8A47_RS06430	ENOG4105DEI	Mannitol dehydrogenase
E8A47_RS06435	ENOG4105CMG	Carbohydrate kinase
E8A47_RS06440	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
E8A47_RS06450	ENOG4108V7B	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity)
E8A47_RS06455	ENOG4105TMB	Formate nitrite transporter
E8A47_RS06460	ENOG4108JUA	Transcriptional regulator
E8A47_RS06465	ENOG4105DFG	type I secretion outer membrane protein
E8A47_RS06470	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
E8A47_RS06500	ENOG4105CH6	catalase
E8A47_RS06505	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
E8A47_RS06525	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
E8A47_RS06540	ENOG4105BZN	citrate synthase
E8A47_RS06545	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
E8A47_RS06550	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
E8A47_RS06555	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
E8A47_RS06560	ENOG4105E33	succinate dehydrogenase
E8A47_RS06565	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
E8A47_RS06570	ENOG4105C7S	Dehydrogenase
E8A47_RS06575	ENOG4107QN2	dihydrolipoyl dehydrogenase
E8A47_RS06585	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
E8A47_RS06605	ENOG4105C8Q	Methyl-accepting chemotaxis
E8A47_RS06615	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
E8A47_RS06635	ENOG4108AZI	Catalyzes the hydrolysis of 4-amino-2-methyl-5- hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2- methyl-5-hydroxymethylpyrimidine phosphate (HMP-P) (By similarity)
E8A47_RS06660	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
E8A47_RS06665	ENOG4107R39	(ABC) transporter
E8A47_RS06695	ENOG4105E0F	Histidine kinase
E8A47_RS06715	ENOG4108IJ9	(ABC) transporter
E8A47_RS06720	ENOG4105C94	Transporter
E8A47_RS06730	ENOG4105CM6	amino acid regulated cytosolic protein
E8A47_RS06740	ENOG4105DSB	aldose 1-epimerase
E8A47_RS06755	ENOG4107TT5	NLP P60 protein
E8A47_RS06760	ENOG4105D94	Major Facilitator Superfamily
E8A47_RS06765	ENOG4105EFJ	Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity)
E8A47_RS06770	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
E8A47_RS06775	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
E8A47_RS06785	ENOG4105DEF	Extracellular solute-binding protein, family 5
E8A47_RS06790	ENOG4105MRR	Transcriptional regulator (By similarity)
E8A47_RS06795	ENOG4108YZY	peptidylprolyl cis-trans isomerase
E8A47_RS06805	ENOG4108XTF	Outer Membrane Lipoprotein
E8A47_RS06810	ENOG4107RET	Isocitrate lyase
E8A47_RS06820	ENOG4105EZE	Cupin 4 family protein
E8A47_RS06825	ENOG4107QTF	adenylosuccinate lyase
E8A47_RS06830	ENOG41075W9	High frequency lysogenization protein HflD homolog
E8A47_RS06835	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
E8A47_RS06845	ENOG4108R99	pseudouridine synthase
E8A47_RS06850	ENOG4105E9K	Isocitrate dehydrogenase
E8A47_RS06855	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
E8A47_RS06860	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
E8A47_RS06865	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
E8A47_RS06870	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
E8A47_RS06875	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
E8A47_RS06880	ENOG4105CNU	cell division protein FtsK
E8A47_RS06885	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
E8A47_RS06890	ENOG4105D1H	recombination factor protein RarA
E8A47_RS06900	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
E8A47_RS06905	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
E8A47_RS06910	ENOG4105C7I	Dehydrogenase
E8A47_RS06915	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
E8A47_RS06920	ENOG4105WFT	During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity)
E8A47_RS06925	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
E8A47_RS06940	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
E8A47_RS06945	ENOG4105D0M	Protease HtpX homolog
E8A47_RS06950	ENOG4105CHM	Aminotransferase
E8A47_RS06955	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
E8A47_RS06960	ENOG4105E0X	reductase
E8A47_RS06965	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
E8A47_RS06970	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E8A47_RS06980	ENOG4105CH5	extracellular solute-binding protein, family 7
E8A47_RS07015	ENOG4105DA5	(ABC) transporter
E8A47_RS07020	ENOG4105E3A	(ABC) transporter
E8A47_RS07025	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
E8A47_RS07125	ENOG4105F04	LysR family Transcriptional regulator
E8A47_RS07150	ENOG4105CBP	Major Facilitator
E8A47_RS07155	ENOG4105C8J	)-transporter
E8A47_RS07170	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
E8A47_RS07175	ENOG4108JJ6	Type I secretion system ATPase
E8A47_RS07190	ENOG4105D3Q	Sugar transferase
E8A47_RS07195	ENOG4108KBE	Glycosyl transferase, family 2
E8A47_RS07215	ENOG4105EY8	ABC transporter
E8A47_RS07300	ENOG4105ER2	Ompa motb domain protein
E8A47_RS07305	ENOG4108ZFX	Mannosyl-3-phosphoglycerate phosphatase
E8A47_RS07310	ENOG4105C3Q	Glycosyl transferase, family 2
E8A47_RS07320	ENOG4105C8Q	Methyl-accepting chemotaxis
E8A47_RS07335	ENOG4105KFG	YeeE YedE family protein
E8A47_RS07340	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
E8A47_RS07345	ENOG4105DHQ	Histidine kinase
E8A47_RS07350	ENOG41090Y2	cytochrome C
E8A47_RS07360	ENOG4108KHN	disulfide isomerase, thiol-disulfide oxidase
E8A47_RS07365	ENOG4107QW3	Sucrose phosphorylase
E8A47_RS07370	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
E8A47_RS07375	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
E8A47_RS07380	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
E8A47_RS07385	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
E8A47_RS07390	ENOG4107YIM	Involved in the transcription termination process (By similarity)
E8A47_RS07395	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
E8A47_RS07400	ENOG4108ZAI	phosphatidylglycerophosphatase a
E8A47_RS07410	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
E8A47_RS07415	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
E8A47_RS07415	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
E8A47_RS07420	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
E8A47_RS07420	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
E8A47_RS07425	ENOG4105C01	Dihydroxy-acid dehydratase
E8A47_RS07430	ENOG4105D9R	oxidoreductase
E8A47_RS07435	ENOG4107RK2	ADP-ribose diphosphatase NudE
E8A47_RS07440	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
E8A47_RS07445	ENOG4105VEJ	Heat shock protein
E8A47_RS07450	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
E8A47_RS07455	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
E8A47_RS07480	ENOG4105BZM	domain protein
E8A47_RS07490	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
E8A47_RS07500	ENOG4105KME	endoribonuclease L-psp
E8A47_RS07510	ENOG4108IV0	ABC, transporter
E8A47_RS07515	ENOG4105C2J	ABC transporter
E8A47_RS07525	ENOG4105C32	Amino acid ABC transporter (Permease)
E8A47_RS07540	ENOG4105C1G	acyl-Coa dehydrogenase
E8A47_RS07545	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
E8A47_RS07555	ENOG4105DTD	Dehydrogenase
E8A47_RS07565	ENOG4105PBF	Anti-RNA polymerase sigma 70 factor
E8A47_RS07580	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
E8A47_RS07595	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
E8A47_RS07605	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
E8A47_RS07610	ENOG4105HF0	Membrane
E8A47_RS07615	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
E8A47_RS07660	ENOG4107V1M	polysaccharide export protein
E8A47_RS07685	ENOG4105CY0	Metallo-Beta-Lactamase
E8A47_RS07695	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
E8A47_RS07700	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
E8A47_RS07705	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
E8A47_RS07720	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
E8A47_RS07740	ENOG4105K64	Glycosyl transferase, family 2
E8A47_RS07760	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
E8A47_RS07775	ENOG4105K64	Glycosyl transferase, family 2
E8A47_RS07805	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
E8A47_RS07825	ENOG4105C11	sulfate adenylyltransferase), subunit 2
E8A47_RS07835	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
E8A47_RS07840	ENOG4108UK5	Transposase
E8A47_RS07860	ENOG4107T7U	Sulfatase
E8A47_RS07870	ENOG41084CK	capsule polysaccharide
E8A47_RS07880	ENOG4105BZU	Histidine kinase
E8A47_RS07895	ENOG4105DFP	Integrase
E8A47_RS07950	ENOG4105F2I	Transposase
E8A47_RS08020	ENOG4105CZE	histidine utilization repressor
E8A47_RS08025	ENOG4105DWD	nucleoside recognition domain protein
E8A47_RS08030	ENOG4105CI2	imidazolone-5-propionate hydrolase
E8A47_RS08035	ENOG41088SP	formiminoglutamate hydrolase
E8A47_RS08045	ENOG4105C84	Histidine ammonia-lyase
E8A47_RS08050	ENOG4105D3Y	Na H antiporter
E8A47_RS08070	ENOG4108RH0	Crea protein
E8A47_RS08075	ENOG4106UY4	Inherit from COG: Scp-like extracellular
E8A47_RS08080	ENOG410606W	general stress protein
E8A47_RS08100	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
E8A47_RS08125	ENOG4105CHW	UPF0052 protein
E8A47_RS08130	ENOG4105ECQ	AraC Family Transcriptional Regulator
E8A47_RS08155	ENOG4105DE9	3-keto-5-aminohexanoate cleavage enzyme
E8A47_RS08170	ENOG4108I0Y	(ABC) transporter
E8A47_RS08180	ENOG4107XBN	GntR Family Transcriptional Regulator
E8A47_RS08185	ENOG4108ERU	trap dicarboxylate transporter subunit DctP
E8A47_RS08195	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E8A47_RS08205	ENOG4105CXK	mandelate racemase muconate lactonizing
E8A47_RS08210	ENOG4105CPQ	Dehydrogenase
E8A47_RS08215	ENOG4105GQU	Trap dicarboxylate transporter, dctp subunit
E8A47_RS08220	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
E8A47_RS08225	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E8A47_RS08230	ENOG4105DEI	Mannitol dehydrogenase
E8A47_RS08235	ENOG4108IA2	Sodium pantothenate symporter
E8A47_RS08250	ENOG4106KNT	transcriptional regulator
E8A47_RS08265	ENOG4105CHR	reductase
E8A47_RS08270	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
E8A47_RS08275	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E8A47_RS08285	ENOG4108ERU	trap dicarboxylate transporter subunit DctP
E8A47_RS08290	ENOG4107UB3	HAD-superfamily hydrolase subfamily IA variant 3
E8A47_RS08300	ENOG4105D7K	pfkb domain protein
E8A47_RS08305	ENOG4108M60	Transcriptional regulator
E8A47_RS08330	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
E8A47_RS08335	ENOG4105C6F	GntR Family Transcriptional Regulator
E8A47_RS08340	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
E8A47_RS08350	ENOG4105CPQ	Dehydrogenase
E8A47_RS08360	ENOG4108RRZ	Transcription elongation factor GreB
E8A47_RS08370	ENOG41087AY	ADP-Ribose pyrophosphatase
E8A47_RS08375	ENOG4108SX3	cytoplasmic protein
E8A47_RS08380	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
E8A47_RS08385	ENOG4105C11	sulfate adenylyltransferase), subunit 2
E8A47_RS08390	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
E8A47_RS08400	ENOG4105CDA	abc transporter atp-binding protein
E8A47_RS08415	ENOG4108Z0Z	intracellular protease Pfpi family
E8A47_RS08435	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
E8A47_RS08445	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
E8A47_RS08450	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
E8A47_RS08455	ENOG4107QP8	phosphohexose isomerase
E8A47_RS08460	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E8A47_RS08465	ENOG4105C8Q	Methyl-accepting chemotaxis
E8A47_RS08470	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E8A47_RS08475	ENOG4105EAC	phosphoserine phosphatase
E8A47_RS08480	ENOG4105KJM	monovalent cation h antiporter subunit g
E8A47_RS08485	ENOG4105W4C	monovalent cation H antiporter subunit F
E8A47_RS08490	ENOG4105SC1	monovalent cation H antiporter subunit E
E8A47_RS08495	ENOG4107R4Z	monovalent cation h antiporter subunit d
E8A47_RS08500	ENOG4108ZE9	Monovalent cation H antiporter subunit C
E8A47_RS08505	ENOG4105D65	subunit l
E8A47_RS08525	ENOG4105DZG	Dehydrogenase
E8A47_RS08535	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
E8A47_RS08540	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
E8A47_RS08545	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
E8A47_RS08560	ENOG4105XEA	Tetr family transcriptional regulator
E8A47_RS08565	ENOG4105DJ4	phosphatidylserine decarboxylase
E8A47_RS08570	ENOG4105KHC	sulfurtransferase
E8A47_RS08575	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
E8A47_RS08590	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E8A47_RS08595	ENOG4105CXK	mandelate racemase muconate lactonizing
E8A47_RS08600	ENOG4105CHR	reductase
E8A47_RS08605	ENOG4105CPQ	Dehydrogenase
E8A47_RS08620	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
E8A47_RS08625	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
E8A47_RS08630	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
E8A47_RS08635	ENOG4105K8N	protein family UPF0079, ATPase
E8A47_RS08640	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
E8A47_RS08645	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
E8A47_RS08650	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
E8A47_RS08655	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
E8A47_RS08660	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
E8A47_RS08665	ENOG4107QJR	hflk protein
E8A47_RS08670	ENOG4105EPW	hflc protein
E8A47_RS08675	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
E8A47_RS08680	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
E8A47_RS08685	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
E8A47_RS08690	ENOG4108VPT	UPF0234 protein
E8A47_RS08695	ENOG4105CD8	aminopeptidase N
E8A47_RS08700	ENOG4107TE5	Lipid kinase
E8A47_RS08710	ENOG4105VEQ	Cold shock protein
E8A47_RS08720	ENOG4107SC1	transglycosylase
E8A47_RS08730	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
E8A47_RS08740	ENOG4108BY2	phosphohistidine phosphatase
E8A47_RS08745	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
E8A47_RS08750	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
E8A47_RS08755	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
E8A47_RS08765	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
E8A47_RS08775	ENOG4108Z03	MAF-like protein
E8A47_RS08780	ENOG4105C03	ribonuclease
E8A47_RS08790	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
E8A47_RS08795	ENOG4105N42	UPF0307 protein
E8A47_RS08800	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
E8A47_RS08805	ENOG41080Z8	PHOSPHOCARRIER protein
E8A47_RS08810	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
E8A47_RS08815	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
E8A47_RS08820	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
E8A47_RS08825	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E8A47_RS08830	ENOG4108IUZ	ABC transporter
E8A47_RS08835	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
E8A47_RS08850	ENOG4105C2X	Arabinose 5-phosphate isomerase
E8A47_RS08855	ENOG4105DHJ	ABC, transporter
E8A47_RS08860	ENOG4105CY3	ABC transporter, permease
E8A47_RS08865	ENOG4107PE3	Mammalian cell entry related domain protein
E8A47_RS08880	ENOG4105VFK	BolA family
E8A47_RS08885	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
E8A47_RS08890	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
E8A47_RS08895	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
E8A47_RS08900	ENOG4105C0H	protease
E8A47_RS08905	ENOG4107QNR	UPF0135 protein
E8A47_RS08910	ENOG4108W2Q	Cytochrome d ubiquinol oxidase subunit III
E8A47_RS08915	ENOG4105D6Z	AFG1 family ATPase
E8A47_RS08920	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
E8A47_RS08930	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
E8A47_RS08935	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
E8A47_RS08940	ENOG4105EIX	cytochrome c1
E8A47_RS08945	ENOG4107MKT	Stringent starvation protein a
E8A47_RS08950	ENOG4105KB2	stringent starvation protein b
E8A47_RS08955	ENOG4105W4M	Transport-associated protein
E8A47_RS08960	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
E8A47_RS08965	ENOG41082RQ	UPF0102 protein
E8A47_RS08970	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
E8A47_RS08975	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
E8A47_RS08985	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
E8A47_RS08990	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
E8A47_RS08995	ENOG4105CJN	penicillin-binding protein
E8A47_RS09000	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
E8A47_RS09005	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
E8A47_RS09010	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
E8A47_RS09015	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
E8A47_RS09020	ENOG4105CNI	cell division protein FtsW
E8A47_RS09025	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
E8A47_RS09030	ENOG4105DFU	Cell wall formation (By similarity)
E8A47_RS09035	ENOG4105CPF	Cell wall formation (By similarity)
E8A47_RS09040	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
E8A47_RS09045	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
E8A47_RS09050	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
E8A47_RS09055	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
E8A47_RS09070	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
E8A47_RS09075	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
E8A47_RS09080	ENOG4108UB3	Thiamine monophosphate
E8A47_RS09090	ENOG4105DWY	Agmatine deiminase
E8A47_RS09095	ENOG4105D60	lipoprotein releasing system transmembrane protein
E8A47_RS09100	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
E8A47_RS09110	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
E8A47_RS09115	ENOG4105BZ1	(ABC) transporter
E8A47_RS09120	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
E8A47_RS09125	ENOG4105W49	UPF0434 protein
E8A47_RS09130	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
E8A47_RS09135	ENOG4105KJF	protein tyrosine phosphatase
E8A47_RS09145	ENOG4105C03	ribonuclease
E8A47_RS09150	ENOG4105EI2	Pseudouridine synthase
E8A47_RS09155	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
E8A47_RS09165	ENOG4108UHJ	MAF-like protein
E8A47_RS09170	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
E8A47_RS09175	ENOG4105VGS	50s ribosomal protein l32
E8A47_RS09180	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
E8A47_RS09185	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
E8A47_RS09190	ENOG4105CHR	reductase
E8A47_RS09195	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
E8A47_RS09200	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
E8A47_RS09210	ENOG4105HHA	aminodeoxychorismate lyase
E8A47_RS09215	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
E8A47_RS09220	ENOG4107QRG	dna polymerase iii
E8A47_RS09230	ENOG4105F8V	Hydrolase, tatD family
E8A47_RS09240	ENOG4105C4R	Atp-dependent dna helicase
E8A47_RS09260	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
E8A47_RS09265	ENOG4105BZJ	Electron transfer flavoprotein
E8A47_RS09270	ENOG4105C10	Electron transfer flavoprotein
E8A47_RS09275	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
E8A47_RS09285	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
E8A47_RS09290	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
E8A47_RS09300	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
E8A47_RS09310	ENOG4105FDR	Membrane
E8A47_RS09330	ENOG4109015	Biopolymer transport protein exbD tolR
E8A47_RS09345	ENOG4105CGK	Exodeoxyribonuclease III
E8A47_RS09360	ENOG4105DVT	helicase
E8A47_RS09365	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
E8A47_RS09370	ENOG4105EMN	RNA polymerase sigma factor
E8A47_RS09390	ENOG4105C0H	protease
E8A47_RS09395	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
E8A47_RS09400	ENOG4105C3F	Signal peptidase i
E8A47_RS09405	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
E8A47_RS09415	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
E8A47_RS09420	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
E8A47_RS09425	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
E8A47_RS09430	ENOG4105BZU	Histidine kinase
E8A47_RS09435	ENOG4105C6T	cysteine synthase
E8A47_RS09440	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
E8A47_RS09445	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
E8A47_RS09450	ENOG4105DXN	mazG family
E8A47_RS09455	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
E8A47_RS09465	ENOG4105FE9	pseudouridine synthase
E8A47_RS09485	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
E8A47_RS09520	ENOG4105CS6	Rhs element vgr protein
E8A47_RS09530	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
E8A47_RS09535	ENOG4105CEY	Amp-dependent synthetase and ligase
E8A47_RS09540	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
E8A47_RS09550	ENOG4105CGU	Enoyl-CoA hydratase
E8A47_RS09555	ENOG4107QX3	carboxylase
E8A47_RS09560	ENOG4105C1G	acyl-Coa dehydrogenase
E8A47_RS09570	ENOG4105C0Z	ABC transporter
E8A47_RS09575	ENOG4108IV0	ABC, transporter
E8A47_RS09585	ENOG4105C32	Amino acid ABC transporter (Permease)
E8A47_RS09595	ENOG4105C1G	acyl-Coa dehydrogenase
E8A47_RS09600	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
E8A47_RS09605	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
E8A47_RS09610	ENOG4108TGY	Glutathione S-transferase
E8A47_RS09615	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
E8A47_RS09625	ENOG4108MIB	
E8A47_RS09665	ENOG410841Q	phosphoesterase PA-phosphatase related protein
E8A47_RS09695	ENOG4105U3E	Transcriptional regulator
E8A47_RS09705	ENOG410829K	Lysine exporter protein (Lyse ygga)
E8A47_RS09735	ENOG4105ERG	peptidase m48, ste24p
E8A47_RS09740	ENOG4105BZU	Histidine kinase
E8A47_RS09760	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
E8A47_RS09780	ENOG4105BZU	Histidine kinase
E8A47_RS09795	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
E8A47_RS09800	ENOG4108V0P	LemA family
E8A47_RS09805	ENOG4105D0M	Protease HtpX homolog
E8A47_RS09820	ENOG410829K	Lysine exporter protein (Lyse ygga)
E8A47_RS09830	ENOG4107U5X	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
E8A47_RS09835	ENOG4105ETT	transcriptional Regulator, LysR family
E8A47_RS09840	ENOG4105KT7	mgtC SapB transporter
E8A47_RS09845	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
E8A47_RS09850	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
E8A47_RS09855	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
E8A47_RS09865	ENOG4108YZY	peptidylprolyl cis-trans isomerase
E8A47_RS09890	ENOG4105BZU	Histidine kinase
E8A47_RS09905	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
E8A47_RS09915	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
E8A47_RS09920	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
E8A47_RS09925	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
E8A47_RS09930	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
E8A47_RS09940	ENOG4105E98	transcriptional regulator DeoR family
E8A47_RS09945	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
E8A47_RS09955	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
E8A47_RS09980	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
E8A47_RS09985	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
E8A47_RS09990	ENOG4107QPN	acyl-Coa dehydrogenase
E8A47_RS10025	ENOG4105D0S	secretion protein (HlyD
E8A47_RS10030	ENOG4105CJ1	ABC, transporter
E8A47_RS10035	ENOG4105CMI	transporter
E8A47_RS10065	ENOG4105CPQ	Dehydrogenase
E8A47_RS10080	ENOG4105CD5	CoA-binding domain protein
E8A47_RS10095	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
E8A47_RS10100	ENOG4105VN1	Heat shock protein
E8A47_RS10115	ENOG4105D3Q	Sugar transferase
E8A47_RS10120	ENOG4105PF3	O-Antigen polymerase
E8A47_RS10125	ENOG4107S90	membrAne
E8A47_RS10140	ENOG4105DAY	polysaccharide export protein
E8A47_RS10150	ENOG4105BZ1	(ABC) transporter
E8A47_RS10175	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
E8A47_RS10185	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
E8A47_RS10190	ENOG4105K64	Glycosyl transferase, family 2
E8A47_RS10200	ENOG4105K64	Glycosyl transferase, family 2
E8A47_RS10220	ENOG4105EXC	Acyl-transferase
E8A47_RS10225	ENOG4107QRS	glycosyltransferase group 2 family protein
E8A47_RS10235	ENOG4105KST	dependent repressor
E8A47_RS10245	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
E8A47_RS10260	ENOG4105D3Y	Na H antiporter
E8A47_RS10270	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
E8A47_RS10275	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
E8A47_RS10320	ENOG4105MJ2	Competence protein
E8A47_RS10325	ENOG4105E27	serine threonine protein kinase
E8A47_RS10335	ENOG4105EUJ	GTP cyclohydrolase i
E8A47_RS10340	ENOG4105C26	Dehydrogenase
E8A47_RS10345	ENOG4105DC1	bifunctional purine biosynthesis protein purh
E8A47_RS10350	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
E8A47_RS10355	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
E8A47_RS10360	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
E8A47_RS10365	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
E8A47_RS10370	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
E8A47_RS10375	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
E8A47_RS10380	ENOG4105EMU	Dehydrogenase
E8A47_RS10385	ENOG4105CF7	AraC family transcriptional regulator
E8A47_RS10390	ENOG4105EQ2	LysR family Transcriptional regulator
E8A47_RS10395	ENOG4105CB2	alcohol dehydrogenase
E8A47_RS10400	ENOG4105C26	Dehydrogenase
E8A47_RS10405	ENOG4105F0N	pyrophosphate phospho-hydrolase
E8A47_RS10415	ENOG4105CTQ	phosphohexokinase
E8A47_RS10420	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
E8A47_RS10425	ENOG4105CDH	Citrulline--aspartate ligase
E8A47_RS10440	ENOG4105BZU	Histidine kinase
E8A47_RS10445	ENOG4105BZU	Histidine kinase
E8A47_RS10455	ENOG4108IRC	dna polymerase iii
E8A47_RS10460	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
E8A47_RS10470	ENOG4105CSM	endonuclease III
E8A47_RS10475	ENOG4105DZB	Electron transport complex
E8A47_RS10480	ENOG4108UQQ	Electron transport complex
E8A47_RS10485	ENOG4105D6A	Electron transport complex
E8A47_RS10495	ENOG4108R3D	Electron transport complex
E8A47_RS10500	ENOG4105DGN	Electron transport complex
E8A47_RS10505	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
E8A47_RS10520	ENOG4105DH7	May be involved in recombination (By similarity)
E8A47_RS10525	ENOG4108TGP	Thioesterase superfamily protein
E8A47_RS10530	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E8A47_RS10535	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
E8A47_RS10545	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
E8A47_RS10555	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
E8A47_RS10580	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
E8A47_RS10600	ENOG4107QHF	type ii secretion system protein e
E8A47_RS10630	ENOG4105C5I	Dehydrogenase
E8A47_RS10650	ENOG4105EUB	pirin domain protein
E8A47_RS10655	ENOG410829K	Lysine exporter protein (Lyse ygga)
E8A47_RS10660	ENOG4107YCY	Transcriptional regulator
E8A47_RS10680	ENOG4108ZHJ	Organic hydroperoxide resistance protein
E8A47_RS10690	ENOG4105KVH	Transcriptional regulator
E8A47_RS10720	ENOG4107R3J	Transporter
E8A47_RS10735	ENOG4105WH1	Two component transcriptional regulator luxr family
E8A47_RS10740	ENOG4105BZU	Histidine kinase
E8A47_RS10765	ENOG4108T0W	nitrous oxide maturation protein NosY
E8A47_RS10770	ENOG4105CIG	ABC transporter
E8A47_RS10775	ENOG4105DH4	Periplasmic copper-binding protein
E8A47_RS10795	ENOG4105K78	MarR family Transcriptional regulator
E8A47_RS10810	ENOG4105DSQ	Nitric oxide reductase
E8A47_RS10815	ENOG4105GMT	ATPase associated with various cellular activities aaa_5
E8A47_RS10845	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
E8A47_RS10860	ENOG4105KPV	Transcriptional regulator
E8A47_RS10865	ENOG4105F1A	Pyruvate formate-lyase
E8A47_RS10880	ENOG4105N1P	Ferredoxin-type protein
E8A47_RS10885	ENOG4108NEM	leader-binding protein dmsD
E8A47_RS10890	ENOG4107KGK	dmso reductase anchor subunit
E8A47_RS10895	ENOG4105QAX	Iron-sulfur
E8A47_RS10900	ENOG4107QY8	reductase
E8A47_RS10915	ENOG4105D4P	Coproporphyrinogen iii oxidase
E8A47_RS10920	ENOG4105CRU	nitrate reductase, alpha subunit
E8A47_RS10925	ENOG4108IUE	nitrate reductase beta subunit
E8A47_RS10930	ENOG4105R3A	Nitrate reductase
E8A47_RS10935	ENOG41076YT	nitrate reductase, gamma subunit
E8A47_RS10940	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
E8A47_RS10945	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
E8A47_RS10950	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
E8A47_RS10960	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
E8A47_RS10980	ENOG4105EWT	decarboxylase family
E8A47_RS10985	ENOG4105DUM	transcriptional regulator, lysR family
E8A47_RS10995	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
E8A47_RS11000	ENOG4105BZG	amino acid carrier protein
E8A47_RS11005	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
E8A47_RS11020	ENOG4105GZI	Transcriptional regulator
E8A47_RS11025	ENOG4107QP7	CoA-transferase subunit A
E8A47_RS11040	ENOG41090BQ	Glutaredoxin
E8A47_RS11055	ENOG4108UYB	regulatoR
E8A47_RS11060	ENOG4105BZU	Histidine kinase
E8A47_RS11070	ENOG4105EKE	dihydroorotase
E8A47_RS11075	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
E8A47_RS11080	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
E8A47_RS11125	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
E8A47_RS11130	ENOG4105EYA	deoxyribonuclease
E8A47_RS11135	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
E8A47_RS11150	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
E8A47_RS11155	ENOG4108S0J	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'- phosphates (By similarity)
E8A47_RS11165	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
E8A47_RS11170	ENOG4107YNJ	LysR family Transcriptional regulator
E8A47_RS11180	ENOG4107S2Z	UPF0761 membrane protein
E8A47_RS11185	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
E8A47_RS11190	ENOG4105C5I	Dehydrogenase
E8A47_RS11200	ENOG4105C9M	aspartyl-trna synthetase
E8A47_RS11205	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
E8A47_RS11210	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
E8A47_RS11215	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
E8A47_RS11220	ENOG4107YD3	Thioesterase
E8A47_RS11225	ENOG4105E02	MotA TolQ exbB proton channel
E8A47_RS11230	ENOG4105M8F	Biopolymer transport protein exbD tolR
E8A47_RS11240	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
E8A47_RS11245	ENOG4105KCK	Peptidoglycan-associated lipoprotein
E8A47_RS11255	ENOG4105UBK	short-chain dehydrogenase reductase
E8A47_RS11260	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
E8A47_RS11265	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
E8A47_RS11270	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
E8A47_RS11275	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
E8A47_RS11285	ENOG4105CFU	surface antigen
E8A47_RS11290	ENOG4105MA0	exported protein
E8A47_RS11295	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
E8A47_RS11305	ENOG41077A9	carbonic anhydrase
E8A47_RS11310	ENOG4105DC8	reductase
E8A47_RS11315	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
E8A47_RS11320	ENOG4108JPW	Aminotransferase
E8A47_RS11325	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
E8A47_RS11330	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
E8A47_RS11345	ENOG4105MYN	Zinc uptake regulation protein
E8A47_RS11350	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
E8A47_RS11355	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
E8A47_RS11360	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
E8A47_RS11375	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
E8A47_RS11380	ENOG4105C3R	Methionine synthase
E8A47_RS11385	ENOG4107QI1	Mate efflux family protein
E8A47_RS11390	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
E8A47_RS11400	ENOG4108DG9	Smr protein MutS2
E8A47_RS11410	ENOG4105CS1	NAD(P)H quinone oxidoreductase
E8A47_RS11425	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
E8A47_RS11430	ENOG4105CD5	CoA-binding domain protein
E8A47_RS11455	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
E8A47_RS11465	ENOG4108MN8	Membrane
E8A47_RS11490	ENOG4105C94	Transporter
E8A47_RS11585	ENOG4105MEW	serine threonine protein phosphatase
E8A47_RS11610	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
E8A47_RS11615	ENOG4105C2J	ABC transporter
E8A47_RS11620	ENOG4105CNN	ABC, transporter
E8A47_RS11625	ENOG4108R85	Short chain dehydrogenase
E8A47_RS11630	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
E8A47_RS11635	ENOG4105ETE	Transcriptional regulator (LacI family
E8A47_RS11640	ENOG4105D3R	alkyl hydroperoxide reductase
E8A47_RS11645	ENOG4107QPB	Beta-lactamase domain protein
E8A47_RS11665	ENOG410829K	Lysine exporter protein (Lyse ygga)
E8A47_RS11670	ENOG4108YXU	transcriptional regulator AsnC family
E8A47_RS11690	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
E8A47_RS11695	ENOG4106WHD	Tetrathionate reductase
E8A47_RS11700	ENOG4105DB1	molybdopterin oxidoreductase
E8A47_RS11705	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
E8A47_RS11755	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
E8A47_RS11760	ENOG4107Z6I	Thiamine biosynthesis protein
E8A47_RS11770	ENOG4105EV9	Alpha Beta Hydrolase
E8A47_RS11775	ENOG4105EX9	Membrane
E8A47_RS11780	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
E8A47_RS11785	ENOG41080HT	Transcriptional regulator, arsr family
E8A47_RS11790	ENOG4105ERU	peptidase
E8A47_RS11800	ENOG4105E09	nadh pyrophosphatase
E8A47_RS11805	ENOG4107RZZ	dna polymerase iii epsilon subunit
E8A47_RS11810	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
E8A47_RS11820	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
E8A47_RS11825	ENOG4105E9H	Lytic Murein transglycosylase
E8A47_RS11835	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
E8A47_RS11840	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
E8A47_RS11845	ENOG4108JQ5	ABC transporter
E8A47_RS11850	ENOG4105I08	Pseudouridine synthase
E8A47_RS11860	ENOG4105FR1	rard protein
E8A47_RS11870	ENOG4105CHH	sulfate transporter
E8A47_RS11885	ENOG41060WC	Enoyl-CoA hydratase
E8A47_RS11890	ENOG4105CC9	acyl-Coa dehydrogenase
E8A47_RS11895	ENOG4105C1G	acyl-Coa dehydrogenase
E8A47_RS11900	ENOG4105CGU	Enoyl-CoA hydratase
E8A47_RS11910	ENOG4105C10	Electron transfer flavoprotein
E8A47_RS11915	ENOG4105BZJ	Electron transfer flavoprotein
E8A47_RS11930	ENOG4105CEY	Amp-dependent synthetase and ligase
E8A47_RS11935	ENOG4105C1G	acyl-Coa dehydrogenase
E8A47_RS11940	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
E8A47_RS11945	ENOG4105CHU	acetyl-coa acetyltransferase
E8A47_RS11950	ENOG4107HP6	Transcriptional regulator
E8A47_RS11980	ENOG4107QSN	dihydrolipoamide acetyltransferase
E8A47_RS11985	ENOG4105CPP	Dehydrogenase, E1 component
E8A47_RS11990	ENOG4107R0V	Pyruvate dehydrogenase
E8A47_RS11995	ENOG4105WJV	Binding-protein-dependent transport systems, inner membrane component
E8A47_RS12000	ENOG4108IJ8	ABC transporter
E8A47_RS12005	ENOG4107T5X	Binding-protein-dependent transport systems, inner membrane component
E8A47_RS12010	ENOG4107SI7	Substrate-binding region of abc-type glycine betaine transport system
E8A47_RS12015	ENOG4105C8N	cysteinyl-tRNA synthetase
E8A47_RS12020	ENOG4105CX6	glutaminyL-tRNA synthetase
E8A47_RS12025	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
E8A47_RS12030	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
E8A47_RS12035	ENOG4105EIN	peptidylprolyl cis-trans isomerase
E8A47_RS12040	ENOG4105K70	DNA-binding protein
E8A47_RS12045	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
E8A47_RS12050	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
E8A47_RS12055	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
E8A47_RS12060	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
E8A47_RS12070	ENOG4105QDK	Flavodoxin
E8A47_RS12080	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
E8A47_RS12085	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
E8A47_RS12090	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
E8A47_RS12095	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
E8A47_RS12100	ENOG41082NX	50s ribosomal protein l35
E8A47_RS12105	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
E8A47_RS12110	ENOG4105C22	threonyL-tRNA synthetase
E8A47_RS12115	ENOG4105CDV	Ompa motb domain protein
E8A47_RS12125	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
E8A47_RS12130	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
E8A47_RS12150	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
E8A47_RS12155	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
E8A47_RS12180	ENOG4105CQ7	ATP-dependent helicase
E8A47_RS12185	ENOG4108R86	Transcriptional regulator
E8A47_RS12195	ENOG4105C7W	Xanthine dehydrogenase
E8A47_RS12205	ENOG4107QUY	Guanine deaminase
E8A47_RS12240	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
E8A47_RS12245	ENOG4108JJ8	(ABC) transporter
E8A47_RS12250	ENOG4108JJ9	ABC, transporter
E8A47_RS12255	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
E8A47_RS12260	ENOG4105C4M	(Ubiquinol oxidase) subunit I
E8A47_RS12270	ENOG4105F1S	paraquat-inducible protein a
E8A47_RS12275	ENOG4105DY2	Paraquat-inducible protein b
E8A47_RS12280	ENOG4108Q2G	(LipO)protein
E8A47_RS12290	ENOG4105C1J	atp-dependent rna helicase
E8A47_RS12300	ENOG4105DJ2	Major Facilitator Superfamily
E8A47_RS12305	ENOG4105HDK	L-asparaginase
E8A47_RS12320	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
E8A47_RS12325	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
E8A47_RS12335	ENOG4105KRS	Proteinase inhibitor
E8A47_RS12345	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
E8A47_RS12350	ENOG4107QIJ	Aconitate hydratase 2
E8A47_RS12355	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
E8A47_RS12360	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
E8A47_RS12365	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
E8A47_RS12375	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
E8A47_RS12380	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
E8A47_RS12390	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
E8A47_RS12395	ENOG4105U5Y	Transcriptional regulator
E8A47_RS12400	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
E8A47_RS12420	ENOG4108ZAF	Molybdopterin
E8A47_RS12425	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
E8A47_RS12430	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
E8A47_RS12435	ENOG4105C2W	permease
E8A47_RS12440	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
E8A47_RS12445	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
E8A47_RS12450	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
E8A47_RS12455	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
E8A47_RS12460	ENOG4105C7N	Xanthine uracil vitamin C permease
E8A47_RS12465	ENOG4108R6K	riboflavin synthase, subunit alpha
E8A47_RS12470	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
E8A47_RS12475	ENOG4108UMI	ABC transporter, permease
E8A47_RS12480	ENOG4105D01	(LipO)protein
E8A47_RS12505	ENOG4105C9Q	fumarate hydratase class II
E8A47_RS12520	ENOG4105C02	permease
E8A47_RS12525	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
E8A47_RS12530	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
E8A47_RS12535	ENOG4105DHP	deoxycytidine triphosphate deaminase
E8A47_RS12550	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
E8A47_RS12555	ENOG4105BZU	Histidine kinase
E8A47_RS12560	ENOG41090A4	Pterin carbinolamine dehydratase
E8A47_RS12565	ENOG4105CGF	Aromatic amino acid aminotransferase
E8A47_RS12580	ENOG4108YYC	ycei family
E8A47_RS12585	ENOG4105DS1	cytochrome b561
E8A47_RS12595	ENOG4105C28	cystathionine
E8A47_RS12600	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
E8A47_RS12615	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
E8A47_RS12620	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
E8A47_RS12625	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
E8A47_RS12635	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
E8A47_RS12640	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
E8A47_RS12650	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
E8A47_RS12655	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
E8A47_RS12660	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
E8A47_RS12665	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
E8A47_RS12670	ENOG4108MP6	LysR family Transcriptional regulator
E8A47_RS12675	ENOG4108UVJ	appr-1-p processing domain protein
E8A47_RS12715	ENOG410829K	Lysine exporter protein (Lyse ygga)
E8A47_RS12745	ENOG4108R3E	Dna-3-methyladenine glycosylase i
E8A47_RS12755	ENOG41062JF	Transcriptional regulator
E8A47_RS12765	ENOG41090PH	Protease synthase and sporulation negative regulatory protein pai 1
E8A47_RS12775	ENOG4105K5X	acetyltransferase
E8A47_RS12780	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
E8A47_RS12800	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
E8A47_RS12870	ENOG4105C8T	Leucyl-tRNA synthetase
E8A47_RS12900	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
E8A47_RS12910	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
E8A47_RS12915	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
E8A47_RS12920	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
E8A47_RS12925	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
E8A47_RS12930	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
E8A47_RS12935	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
E8A47_RS12945	ENOG4108JA2	transcriptioN-repair coupling factor
E8A47_RS12950	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
E8A47_RS12975	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
E8A47_RS12990	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
E8A47_RS12995	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
E8A47_RS13000	ENOG41084BA	UPF0250 protein
E8A47_RS13005	ENOG4105DZ1	carboxypeptidase
E8A47_RS13015	ENOG4105CVE	Lytic murein transglycosylase
E8A47_RS13020	ENOG4105CNI	cell division protein FtsW
E8A47_RS13025	ENOG4105CJN	penicillin-binding protein
E8A47_RS13030	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
E8A47_RS13040	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
E8A47_RS13045	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
E8A47_RS13060	ENOG4108KF1	Membrane
E8A47_RS13065	ENOG410829K	Lysine exporter protein (Lyse ygga)
E8A47_RS13070	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
E8A47_RS13075	ENOG4105DFU	Cell wall formation (By similarity)
E8A47_RS13095	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
E8A47_RS13100	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
E8A47_RS13105	ENOG4105C3U	ABC transporter
E8A47_RS13110	ENOG4108JQ7	(ABC) transporter
E8A47_RS13115	ENOG4107YNJ	LysR family Transcriptional regulator
E8A47_RS13120	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
E8A47_RS13135	ENOG4105F95	Monooxygenase
E8A47_RS13140	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
E8A47_RS13145	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
E8A47_RS13165	ENOG4105KME	endoribonuclease L-psp
E8A47_RS13170	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
E8A47_RS13175	ENOG4105ETE	Transcriptional regulator (LacI family
E8A47_RS13185	ENOG4105E0C	molybdate abc transporter
E8A47_RS13190	ENOG4105NRK	Binding-protein-dependent transport systems, inner membrane component
E8A47_RS13195	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
E8A47_RS13200	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
E8A47_RS13205	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
E8A47_RS13210	ENOG4105CSV	Glutaminase
E8A47_RS13215	ENOG4108VP3	Lysine exporter protein (LysE YggA)
E8A47_RS13225	ENOG4108TM9	integral membrane protein
E8A47_RS13230	ENOG4105KAC	Antibiotic biosynthesis monooxygenase
E8A47_RS13240	ENOG4105F7J	membrane-bound serine protease
E8A47_RS13265	ENOG410645S	MarR family Transcriptional regulator
E8A47_RS13275	ENOG4105ECQ	AraC Family Transcriptional Regulator
E8A47_RS13310	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
E8A47_RS13320	ENOG4105K59	histidine triad (HIT) protein
E8A47_RS13340	ENOG410829K	Lysine exporter protein (Lyse ygga)
E8A47_RS13390	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
E8A47_RS13395	ENOG4107TXC	Transcriptional regulator
E8A47_RS13435	ENOG4108Z4X	TRANSCRIPTIONal
E8A47_RS13465	ENOG4105C1J	atp-dependent rna helicase
E8A47_RS13470	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
E8A47_RS13485	ENOG4108V0E	nucleoside 2-deoxyribosyltransferase YtoQ
E8A47_RS13495	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
E8A47_RS13510	ENOG4105QUC	reductase
E8A47_RS13535	ENOG4105CTK	cobaltochelatase, cobn subunit
E8A47_RS13540	ENOG4107QRP	cobalamin biosynthesis protein CobW
E8A47_RS13545	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
E8A47_RS13550	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
E8A47_RS13565	ENOG4105EHG	Permease protein
E8A47_RS13570	ENOG4105E0A	ABC, transporter
E8A47_RS13575	ENOG41069YE	inner membrane protein yohC
E8A47_RS13595	ENOG4105D52	delta-aminolevulinic acid dehydratase
E8A47_RS13605	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
E8A47_RS13610	ENOG4105EHG	Permease protein
E8A47_RS13615	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
E8A47_RS13620	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
E8A47_RS13635	ENOG4105CVJ	phosphoglycerate mutase
E8A47_RS13640	ENOG4107XPA	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
E8A47_RS13650	ENOG4105CIH	Imidazole acetol-phosphate transaminase
E8A47_RS13655	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
E8A47_RS13660	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
E8A47_RS13665	ENOG4105C01	Dihydroxy-acid dehydratase
E8A47_RS13670	ENOG4105CHC	glucokinase (EC 2.7.1.2)
E8A47_RS13680	ENOG4105D7K	pfkb domain protein
E8A47_RS13690	ENOG4105CXK	mandelate racemase muconate lactonizing
E8A47_RS13695	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
E8A47_RS13700	ENOG4108RTU	Aldolase
E8A47_RS13710	ENOG4107RUZ	Sss sodium solute transporter superfamily
E8A47_RS13715	ENOG4108UHU	Aldolase
E8A47_RS13720	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
E8A47_RS13725	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
E8A47_RS13730	ENOG4107FKK	extracellular solute-binding protein family 1
E8A47_RS13735	ENOG4105D56	permease protein
E8A47_RS13740	ENOG4105EG2	ABC transporter, permease
E8A47_RS13745	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
E8A47_RS13750	ENOG4105C08	Histidine kinase
E8A47_RS13755	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
E8A47_RS13760	ENOG4105C1A	potassium transporter peripheral membrane
E8A47_RS13770	ENOG4105K6V	RNA polymerase
E8A47_RS13785	ENOG4105CG3	alpha amylase, catalytic region
E8A47_RS13790	ENOG41061ZR	Transcriptional regulator
E8A47_RS13800	ENOG4107T3P	ABC, transporter
E8A47_RS13815	ENOG4105CG3	alpha amylase, catalytic region
E8A47_RS13820	ENOG4108IJ9	(ABC) transporter
E8A47_RS13830	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
E8A47_RS13835	ENOG4105CA9	Pyruvate kinase
E8A47_RS13840	ENOG4108Z5K	methylglyoxal synthase
E8A47_RS13845	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
E8A47_RS13850	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
E8A47_RS13855	ENOG4105DE4	1-phosphofructokinase
E8A47_RS13860	ENOG4105DM4	PTS System
E8A47_RS13865	ENOG4107QP8	phosphohexose isomerase
E8A47_RS13875	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
E8A47_RS13900	ENOG4105BZ9	Cytochrome C oxidase, subunit I
E8A47_RS13905	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
E8A47_RS13940	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
E8A47_RS13945	ENOG4105EMK	carboxylate amino acid amine transporter
E8A47_RS13950	ENOG4105VPI	YqaE family transport protein
E8A47_RS13970	ENOG4105C26	Dehydrogenase
E8A47_RS13975	ENOG4105CK7	Sodium proline symporter
E8A47_RS13980	ENOG4105C26	Dehydrogenase
E8A47_RS13990	ENOG41084HI	prevent-host-death family
E8A47_RS14020	ENOG4105EIF	outer membrane protein W
E8A47_RS14025	ENOG4105WP7	tRNA pseudouridine synthase C
E8A47_RS14040	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
E8A47_RS14050	ENOG4107GZ4	SanA protein
E8A47_RS14070	ENOG4105C3K	feS assembly ATPase SufC
E8A47_RS14090	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
E8A47_RS14110	ENOG4105DGU	Histone deacetylase
E8A47_RS14120	ENOG4105CHU	acetyl-coa acetyltransferase
E8A47_RS14135	ENOG4108US0	Transcription regulator that can specifically activate or repress expression of target genes (By similarity)
E8A47_RS14145	ENOG41081QV	Universal stress protein
E8A47_RS14150	ENOG4105C5H	ABC transporter
E8A47_RS14160	ENOG4105CEY	Amp-dependent synthetase and ligase
E8A47_RS14165	ENOG4105CHU	acetyl-coa acetyltransferase
E8A47_RS14170	ENOG4105C1G	acyl-Coa dehydrogenase
E8A47_RS14185	ENOG4105F8V	Hydrolase, tatD family
E8A47_RS14195	ENOG4108BPE	-transporting atpase
E8A47_RS14200	ENOG4107QI1	Mate efflux family protein
E8A47_RS14220	ENOG41061CK	Antibiotic biosynthesis monooxygenase
E8A47_RS14225	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
E8A47_RS14245	ENOG4105CSU	acyl-Coa dehydrogenase
E8A47_RS14265	ENOG4105CHU	acetyl-coa acetyltransferase
E8A47_RS14270	ENOG4105F4P	)-transporter
E8A47_RS14275	ENOG4105C8Q	Methyl-accepting chemotaxis
E8A47_RS14285	ENOG4105CAU	Arsenical resistance protein, ArsH
E8A47_RS14290	ENOG4105D6J	arsenicaL-resistance protein
E8A47_RS14315	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
E8A47_RS14325	ENOG4105C8U	phosphate abc transporter
E8A47_RS14340	ENOG4105C2C	drug resistance transporter, Bcr CflA
E8A47_RS14355	ENOG410903C	(LipO)protein
E8A47_RS14365	ENOG4105CQ7	ATP-dependent helicase
E8A47_RS14370	ENOG4105CEY	Amp-dependent synthetase and ligase
E8A47_RS14375	ENOG4105E7A	Glutamine amidotransferase
E8A47_RS14390	ENOG4108ZZ3	UPF0260 protein
E8A47_RS14400	ENOG4105VNG	YcgL domain-containing protein
E8A47_RS14410	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
E8A47_RS14415	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
E8A47_RS14420	ENOG4107QMP	dna polymerase iii subunits gamma and tau
E8A47_RS14425	ENOG4105M2J	Glutaredoxin
E8A47_RS14430	ENOG4105DBV	ornithine carbamoyltransferase
E8A47_RS14440	ENOG4105WH1	Two component transcriptional regulator luxr family
E8A47_RS14445	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
E8A47_RS14470	ENOG4108IYU	L-aspartate oxidase
E8A47_RS14480	ENOG4105Y75	tpr repeat protein
E8A47_RS14485	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
E8A47_RS14495	ENOG4105CFV	Tetratricopeptide repeat protein
E8A47_RS14500	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
E8A47_RS14510	ENOG4105DXD	2-methylcitrate dehydratase
E8A47_RS14515	ENOG4105C7F	AcnD-accessory protein PrpF
E8A47_RS14520	ENOG4108I0Z	Aconitate hydratase
E8A47_RS14525	ENOG4105BZN	citrate synthase
E8A47_RS14530	ENOG4105CR4	methylisocitrate lyase
E8A47_RS14535	ENOG4105DRR	Transcriptional regulator, GntR family
E8A47_RS14545	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
E8A47_RS14550	ENOG4107R11	Transcriptional regulator
E8A47_RS14555	ENOG4105K63	Thioredoxin
E8A47_RS14560	ENOG4105DSF	transport protein
E8A47_RS14570	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
E8A47_RS14585	ENOG4105CQB	FAD linked oxidase domain protein
E8A47_RS14590	ENOG4105DK0	Indole-3-glycerol phosphate synthase
E8A47_RS14595	ENOG4107QYG	anthranilate phosphoribosyltransferase
E8A47_RS14600	ENOG4105DDQ	anthranilate synthase
E8A47_RS14605	ENOG4105DSE	periplasmic solute binding protein
E8A47_RS14610	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
E8A47_RS14615	ENOG4105CEP	NADH dehydrogenase
E8A47_RS14625	ENOG4108J2H	Sulfate ABC transporter periplasmic sulfate-binding protein
E8A47_RS14630	ENOG4108I5D	sulfate abc transporter
E8A47_RS14635	ENOG4105ECW	sulfate abc transporter
E8A47_RS14640	ENOG4108IJ6	ABC transporter
E8A47_RS14660	ENOG4105FQ6	thiopurine methyltransferase
E8A47_RS14665	ENOG4106MWK	domain protein
E8A47_RS14685	ENOG4105DX0	Hemolysin A
E8A47_RS14690	ENOG4105EGS	Mechanosensitive ion channel
E8A47_RS14695	ENOG4105HDD	phospholipase
E8A47_RS14700	ENOG4105NE1	Conserved Protein
E8A47_RS14725	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
E8A47_RS14740	ENOG4105CBX	hi0933 family
E8A47_RS14750	ENOG4105BZS	acriflavin resistance protein
E8A47_RS14765	ENOG4105D38	putrescine abc transporter
E8A47_RS14770	ENOG4105F38	ABC transporter, permease
E8A47_RS14775	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
E8A47_RS14785	ENOG4105D3R	alkyl hydroperoxide reductase
E8A47_RS14790	ENOG4108JU3	Alkyl hydroperoxide reductase
E8A47_RS14795	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
E8A47_RS14810	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
E8A47_RS14815	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
E8A47_RS14820	ENOG4108DG9	Smr protein MutS2
E8A47_RS14835	ENOG4105CV6	ABC transporter, permease
E8A47_RS14840	ENOG4108I0Y	(ABC) transporter
E8A47_RS14845	ENOG4108UJV	acyl-CoA thioesterase i
E8A47_RS14880	ENOG4108JJA	ABC, transporter
E8A47_RS14885	ENOG4105DFG	type I secretion outer membrane protein
E8A47_RS14905	ENOG4105BZU	Histidine kinase
E8A47_RS14915	ENOG4105C5H	ABC transporter
E8A47_RS14925	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
E8A47_RS14930	ENOG4105K59	histidine triad (HIT) protein
E8A47_RS14935	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
E8A47_RS14945	ENOG4105C12	Phosphoribosylglycinamide synthetase
E8A47_RS14950	ENOG4108NVM	synthesis repressor PhaR
E8A47_RS14960	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
E8A47_RS14965	ENOG4105CVE	Lytic murein transglycosylase
E8A47_RS14970	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
E8A47_RS14980	ENOG4105KJM	monovalent cation h antiporter subunit g
E8A47_RS14985	ENOG41080TA	Multiple resistance and ph regulation protein f
E8A47_RS14990	ENOG4105SC1	monovalent cation H antiporter subunit E
E8A47_RS14995	ENOG4108JPZ	Monovalent cation H antiporter subunit D
E8A47_RS15000	ENOG4105MKQ	Monovalent cation H antiporter subunit C
E8A47_RS15005	ENOG4105GND	monovalent cation H antiporter subunit B
E8A47_RS15010	ENOG4105D65	subunit l
E8A47_RS15015	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
E8A47_RS15020	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
E8A47_RS15040	ENOG4105CDU	Replicative dna helicase
E8A47_RS15045	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
E8A47_RS15055	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
E8A47_RS15060	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
E8A47_RS15065	ENOG4105C2N	RNA methyltransferase TrmH family group 3
E8A47_RS15070	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
E8A47_RS15090	ENOG4105C94	Transporter
E8A47_RS15100	ENOG4108PZW	LysR family Transcriptional regulator
E8A47_RS15120	ENOG4105ED1	spovr family
E8A47_RS15125	ENOG4106AKX	UPF0229 protein
E8A47_RS15130	ENOG4105CYN	Serine protein kinase
E8A47_RS15140	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
E8A47_RS15145	ENOG4108IPJ	Membrane
E8A47_RS15150	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
E8A47_RS15160	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
E8A47_RS15170	ENOG4105ETT	transcriptional Regulator, LysR family
E8A47_RS15190	ENOG4107V8I	Glycosyl transferases group 1
E8A47_RS15195	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
E8A47_RS15200	ENOG4105QNF	Outer membrane lipoprotein
E8A47_RS15205	ENOG4105EJC	lysr family transcriptional regulator
E8A47_RS15210	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
E8A47_RS15220	ENOG4105CS1	NAD(P)H quinone oxidoreductase
E8A47_RS15230	ENOG4107UI5	Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity)
E8A47_RS15235	ENOG4108JEH	abc transporter atp-binding protein
E8A47_RS15240	ENOG4105DSP	amino acid AbC transporter
E8A47_RS15245	ENOG4106YG3	ABC transporter
E8A47_RS15260	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
E8A47_RS15265	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
E8A47_RS15280	ENOG4105C01	Dihydroxy-acid dehydratase
E8A47_RS15285	ENOG4105VUH	addiction module killer protein
E8A47_RS15290	ENOG4105YES	addiction module antidote protein
E8A47_RS15295	ENOG4105DSY	exodeoxyribonuclease V, gamma
E8A47_RS15305	ENOG4107RH7	Nicotinate phosphoribosyltransferase
E8A47_RS15320	ENOG4105ES4	Nitrilase
E8A47_RS15325	ENOG4105CK7	Sodium proline symporter
E8A47_RS15335	ENOG4105EJC	lysr family transcriptional regulator
E8A47_RS15340	ENOG4107QKA	exodeoxyribonuclease V beta
E8A47_RS15345	ENOG4107QYX	exodeoxyribonuclease v alpha
E8A47_RS15470	ENOG4105T38	integral membrane protein
E8A47_RS15475	ENOG4107NQ8	LysR family Transcriptional regulator
E8A47_RS15500	ENOG4105W5Z	
E8A47_RS15515	ENOG4108J5H	Homocysteine s-methyltransferase
E8A47_RS15520	ENOG4108IQI	permease
E8A47_RS15565	ENOG4105DJB	Major Facilitator Superfamily
E8A47_RS15570	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
E8A47_RS15585	ENOG4105C8Q	Methyl-accepting chemotaxis
E8A47_RS15590	ENOG4108R6G	acetyltransferase
E8A47_RS15595	ENOG4105KVH	Transcriptional regulator
E8A47_RS15605	ENOG4105CHR	reductase
E8A47_RS15620	ENOG4105CF7	AraC family transcriptional regulator
E8A47_RS15625	ENOG4108IXY	short-chain dehydrogenase reductase
E8A47_RS15630	ENOG4105ETT	transcriptional Regulator, LysR family
E8A47_RS15635	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
E8A47_RS15645	ENOG4105CJP	fad dependent oxidoreductase
E8A47_RS15655	ENOG4105F38	ABC transporter, permease
E8A47_RS15660	ENOG4105D38	putrescine abc transporter
E8A47_RS15665	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
E8A47_RS15670	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
E8A47_RS15675	ENOG4105C26	Dehydrogenase
E8A47_RS15695	ENOG4108ZHR	arsR family transcriptional regulator
E8A47_RS15730	ENOG41064T2	transcriptional regulator, lysR family
E8A47_RS15740	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
E8A47_RS15745	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
E8A47_RS15760	ENOG4108X0B	nad(p)h dehydrogenase (quinone)
E8A47_RS15770	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
E8A47_RS15780	ENOG4105EQ2	LysR family Transcriptional regulator
E8A47_RS15785	ENOG4105CPC	Aldo Keto reductase
E8A47_RS15790	ENOG4107RSM	transcriptional regulator
E8A47_RS15795	ENOG4105CH2	amidohydrolase
E8A47_RS15805	ENOG4105E1V	na solute symporter
E8A47_RS15835	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
E8A47_RS15840	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
E8A47_RS15855	ENOG4105BZU	Histidine kinase
E8A47_RS15885	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
E8A47_RS15890	ENOG4105C8Q	Methyl-accepting chemotaxis
E8A47_RS15905	ENOG4105D06	uba thif-type nad fad binding protein
E8A47_RS15910	ENOG4105EW9	transcriptional regulator AsnC family
E8A47_RS15915	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
E8A47_RS15920	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
E8A47_RS15925	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
E8A47_RS15930	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
E8A47_RS15935	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
E8A47_RS15940	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
E8A47_RS15950	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
E8A47_RS15955	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
E8A47_RS15960	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
E8A47_RS15965	ENOG4105C3G	gtp-binding protein
E8A47_RS15975	ENOG4105DFM	M18 family aminopeptidase
E8A47_RS15980	ENOG4105CN1	protease
E8A47_RS15985	ENOG41082YX	Transcriptional regulator, arsr family
E8A47_RS16005	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
E8A47_RS16010	ENOG4105C9A	Phoh family
E8A47_RS16015	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
E8A47_RS16020	ENOG4108JU5	Magnesium and cobalt efflux protein
E8A47_RS16025	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
E8A47_RS16030	ENOG4105DQ4	alcohol dehydrogenase
E8A47_RS16035	ENOG4105CF7	AraC family transcriptional regulator
E8A47_RS16045	ENOG4108M0I	Transcriptional regulator
E8A47_RS16050	ENOG4105VRT	cytoplasmic protein
E8A47_RS16070	ENOG4107R7Y	intracellular protease Pfpi family
E8A47_RS16075	ENOG4105C8Q	Methyl-accepting chemotaxis
E8A47_RS16085	ENOG4107XWI	flavin reductase domain protein, FMN-binding
E8A47_RS16090	ENOG4105C5I	Dehydrogenase
E8A47_RS16095	ENOG4108YZN	class I peptide chain release factor
E8A47_RS16105	ENOG4105CTU	Proline racemase
E8A47_RS16120	ENOG4105D7N	magnesium and cobalt transport protein CorA
E8A47_RS16140	ENOG4105C26	Dehydrogenase
E8A47_RS16180	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
E8A47_RS16195	ENOG4105EN6	Membrane
E8A47_RS16230	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
E8A47_RS16255	ENOG4105BZU	Histidine kinase
E8A47_RS16260	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
E8A47_RS16275	ENOG4108ZT1	Transcriptional regulator
E8A47_RS16285	ENOG4108RYK	Nad-dependent epimerase dehydratase
E8A47_RS16310	ENOG4105EY2	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity)
E8A47_RS16315	ENOG4105C26	Dehydrogenase
E8A47_RS16325	ENOG4108T2Z	Arginine
E8A47_RS16330	ENOG4105C8Y	Acetylornithine aminotransferase
E8A47_RS16335	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
E8A47_RS16340	ENOG4105ECQ	AraC Family Transcriptional Regulator
E8A47_RS16350	ENOG4105RKW	reductase (By
E8A47_RS16370	ENOG4105CDY	transcriptional regulatory protein
E8A47_RS16390	ENOG4105CB2	alcohol dehydrogenase
E8A47_RS16395	ENOG4105BZ1	(ABC) transporter
E8A47_RS16410	ENOG4105ETE	Transcriptional regulator (LacI family
E8A47_RS16430	ENOG4105CNV	Aldolase
E8A47_RS16440	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
E8A47_RS16445	ENOG4105CNN	ABC, transporter
E8A47_RS16450	ENOG4105C2J	ABC transporter
E8A47_RS16460	ENOG4105CPQ	Dehydrogenase
E8A47_RS16470	ENOG4105CMT	Dihydroxyacetone kinase
E8A47_RS16475	ENOG4108YZG	isomerase
E8A47_RS16480	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
E8A47_RS16485	ENOG4105CV1	Transketolase (EC 2.2.1.1)
E8A47_RS16495	ENOG4105C1J	atp-dependent rna helicase
E8A47_RS16500	ENOG4108Z66	YbaK ebsC protein
E8A47_RS16525	ENOG4108IAB	Phoh family
E8A47_RS16530	ENOG4107U9T	Pfam:Ribonuclease_BN
E8A47_RS16535	ENOG4105D65	subunit l
E8A47_RS16540	ENOG4108JPZ	Monovalent cation H antiporter subunit D
E8A47_RS16545	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
E8A47_RS16565	ENOG4105VEQ	Cold shock protein
E8A47_RS16575	ENOG4105C26	Dehydrogenase
E8A47_RS16580	ENOG4106KR7	LysR family Transcriptional regulator
E8A47_RS16590	ENOG4105C26	Dehydrogenase
E8A47_RS16595	ENOG4108ZAI	phosphatidylglycerophosphatase a
E8A47_RS16600	ENOG4108Q2J	Inner membrane protein YebE
E8A47_RS16605	ENOG4105EYH	Exonuclease
E8A47_RS16610	ENOG4107RFY	SbcCD D subunit
E8A47_RS16615	ENOG4105C8P	)-transporter
E8A47_RS16620	ENOG4105E2V	Glycosyltransferase 36
E8A47_RS16625	ENOG4108IYC	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
E8A47_RS16630	ENOG4108IMY	Transcriptional regulator
E8A47_RS16650	ENOG4105DQ5	transport system permease protein
E8A47_RS16655	ENOG4108IHU	transport system permease protein
E8A47_RS16665	ENOG4105E0A	ABC, transporter
E8A47_RS16670	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E8A47_RS16685	ENOG4105CTU	Proline racemase
E8A47_RS16690	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
E8A47_RS16695	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
E8A47_RS16700	ENOG4105G3Z	GntR family transcriptional regulator
E8A47_RS16715	ENOG4105E5Q	amino acid AbC transporter
E8A47_RS16720	ENOG4105E5Q	amino acid AbC transporter
E8A47_RS16730	ENOG4105CTU	Proline racemase
E8A47_RS16735	ENOG4105E0K	tonB-dependent siderophore receptor
E8A47_RS16750	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
E8A47_RS16765	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
E8A47_RS16785	ENOG4105ENA	helicase
E8A47_RS16805	ENOG4105X54	addiction module antidote protein
E8A47_RS16860	ENOG4105BZ1	(ABC) transporter
E8A47_RS16865	ENOG4105E0A	ABC, transporter
E8A47_RS16870	ENOG4108IHU	transport system permease protein
E8A47_RS16875	ENOG4105DQ5	transport system permease protein
E8A47_RS16880	ENOG4108MES	Periplasmic binding protein
E8A47_RS16885	ENOG4105D05	Receptor
E8A47_RS16890	ENOG4105D05	Receptor
E8A47_RS16895	ENOG4108R4R	Iron-regulated virulence regulatory protein
E8A47_RS16910	ENOG4105BZU	Histidine kinase
E8A47_RS16915	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E8A47_RS16925	ENOG4108IJ7	Glycine betaine
E8A47_RS16945	ENOG4105C94	Transporter
E8A47_RS16980	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
E8A47_RS17000	ENOG4105CC0	LysR family Transcriptional regulator
E8A47_RS17005	ENOG4105EJQ	L-serine dehydratase
E8A47_RS17010	ENOG4105DHQ	Histidine kinase
E8A47_RS17015	ENOG4105ETX	regulatoR
E8A47_RS17030	ENOG41080IJ	Diacylglycerol kinase
E8A47_RS17035	ENOG4105DIJ	Phosphoethanolamine transferase
E8A47_RS17045	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E8A47_RS17050	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
E8A47_RS17055	ENOG4105VCC	30S ribosomal protein S21
E8A47_RS17060	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
E8A47_RS17065	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
E8A47_RS17080	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
E8A47_RS17085	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
E8A47_RS17100	ENOG4105NWN	ApaG protein
E8A47_RS17105	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
E8A47_RS17110	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
E8A47_RS17115	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
E8A47_RS17120	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
E8A47_RS17125	ENOG4105EHM	Aminoglycoside phosphotransferase
E8A47_RS17130	ENOG4108S0S	Nucleotidyl transferase
E8A47_RS17140	ENOG4108UKZ	OsmC family
E8A47_RS17145	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
E8A47_RS17150	ENOG4105D1S	lipid A biosynthesis
E8A47_RS17155	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
E8A47_RS17160	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E8A47_RS17175	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
E8A47_RS17180	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
E8A47_RS17185	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
E8A47_RS17190	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
E8A47_RS17195	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
E8A47_RS17200	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
E8A47_RS17210	ENOG4107RGH	Aldehyde dehydrogenase
E8A47_RS17215	ENOG4106KNT	transcriptional regulator
E8A47_RS17225	ENOG4105EW9	transcriptional regulator AsnC family
E8A47_RS17230	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
E8A47_RS17250	ENOG4105WMR	Protein CrcB homolog
E8A47_RS17255	ENOG4105WMR	Protein CrcB homolog
E8A47_RS17265	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
E8A47_RS17275	ENOG4105CHH	sulfate transporter
E8A47_RS17280	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
E8A47_RS17285	ENOG4105C59	p-type ATPase
E8A47_RS17290	ENOG4105W1Y	Transcriptional regulator
E8A47_RS17300	ENOG4108WQI	RNA Polymerase
E8A47_RS17310	ENOG4105D3R	alkyl hydroperoxide reductase
E8A47_RS17325	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
E8A47_RS17340	ENOG4105C8Y	Acetylornithine aminotransferase
E8A47_RS17345	ENOG4105C26	Dehydrogenase
E8A47_RS17350	ENOG4108RYR	transcriptional regulator AsnC family
E8A47_RS17355	ENOG4105E5N	succinylglutamate desuccinylase aspartoacylase
E8A47_RS17360	ENOG4105ENR	peptidase, M24
E8A47_RS17365	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
E8A47_RS17375	ENOG4105DWU	Membrane
E8A47_RS17390	ENOG4105HDK	L-asparaginase
E8A47_RS17405	ENOG4105JQN	Transcriptional regulator
E8A47_RS17410	ENOG4105DDY	UPF0142 protein ycaO
E8A47_RS17415	ENOG41064MX	Tetr family transcriptional regulator
E8A47_RS17420	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
E8A47_RS17425	ENOG4105EBM	Alpha Beta Hydrolase Fold protein
E8A47_RS17430	ENOG4105CBN	LysR family transcriptional regulator
E8A47_RS17435	ENOG4105CIS	alcohol dehydrogenase
E8A47_RS17445	ENOG4108WUH	Transcriptional regulator, TetR family
E8A47_RS17460	ENOG4105EB3	Histidine kinase
E8A47_RS17465	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
E8A47_RS17470	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
E8A47_RS17475	ENOG41062D9	Histidine kinase
E8A47_RS17515	ENOG4105C94	Transporter
E8A47_RS17520	ENOG4105CHH	sulfate transporter
E8A47_RS17530	ENOG4105C26	Dehydrogenase
E8A47_RS17540	ENOG4105BZU	Histidine kinase
E8A47_RS17550	ENOG4105BZU	Histidine kinase
E8A47_RS17580	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E8A47_RS17590	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
E8A47_RS17595	ENOG4105ETE	Transcriptional regulator (LacI family
E8A47_RS17610	ENOG4105EAA	nucleoside
E8A47_RS17645	ENOG4108594	Permease of the drug metabolite transporter
E8A47_RS17650	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
E8A47_RS17660	ENOG4108IJ6	ABC transporter
E8A47_RS17665	ENOG4105E0C	molybdate abc transporter
E8A47_RS17670	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
E8A47_RS17675	ENOG4105CA9	Pyruvate kinase
E8A47_RS17680	ENOG4108Z2U	ureidoglycolate hydrolase
E8A47_RS17685	ENOG4105S0E	allantoin catabolism protein
E8A47_RS17700	ENOG4105E5Q	amino acid AbC transporter
E8A47_RS17710	ENOG4105F87	Dehydratase
E8A47_RS17725	ENOG410633P	Hydantoin racemase
E8A47_RS17735	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
E8A47_RS17775	ENOG4105CYM	Glutathione S-transferase
E8A47_RS17785	ENOG4105DAA	L-lactate
E8A47_RS17790	ENOG4108Z0R	Transferase
E8A47_RS17795	ENOG4105CQB	FAD linked oxidase domain protein
E8A47_RS17810	ENOG41060WC	Enoyl-CoA hydratase
E8A47_RS17815	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E8A47_RS17830	ENOG4105DRR	Transcriptional regulator, GntR family
E8A47_RS17835	ENOG4108KWP	DNA-binding transcriptional regulator GlcC
E8A47_RS17840	ENOG4105CQB	FAD linked oxidase domain protein
E8A47_RS17845	ENOG4105EU8	FAD linked oxidase domain protein
E8A47_RS17850	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
E8A47_RS17855	ENOG4108ZJF	Glcg protein
E8A47_RS17890	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
E8A47_RS17905	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
E8A47_RS17910	ENOG4105C58	cytochrome c oxidase accessory protein ccog
E8A47_RS17920	ENOG4105C59	p-type ATPase
E8A47_RS17935	ENOG4105D4P	Coproporphyrinogen iii oxidase
E8A47_RS17950	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
E8A47_RS17955	ENOG4105F5W	AtP-binding protein
E8A47_RS17960	ENOG4105D70	Integrase catalytic subunit
E8A47_RS17980	ENOG4105F2I	Transposase
E8A47_RS18015	ENOG4107Y80	Major Facilitator superfamily
E8A47_RS18060	ENOG4105BZU	Histidine kinase
E8A47_RS18100	ENOG4107QIV	Cytochrome c biogenesis protein
E8A47_RS18105	ENOG4105D3R	alkyl hydroperoxide reductase
E8A47_RS18120	ENOG4108KHN	disulfide isomerase, thiol-disulfide oxidase
E8A47_RS18125	ENOG4108N5C	SNARE associated Golgi protein-related protein
E8A47_RS18130	ENOG4107QX9	Thiol disulfide interChange protein
E8A47_RS18135	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
E8A47_RS18140	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
E8A47_RS18210	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
E8A47_RS18215	ENOG4108IJF	Heavy metal efflux pump, CzcA
E8A47_RS18235	ENOG4105EKQ	RNA-directed DNA polymerase
E8A47_RS18245	ENOG4105C5X	domain protein
E8A47_RS18250	ENOG4105C7H	Helicase, RecD TraA family
E8A47_RS18300	ENOG4107QN1	sodium solute
E8A47_RS18310	ENOG4105BZU	Histidine kinase
E8A47_RS18320	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
E8A47_RS18325	ENOG4105GPY	SprT protein
E8A47_RS18335	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
E8A47_RS18340	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
E8A47_RS18345	ENOG41072GX	Peptidase M22 Glycoprotease
E8A47_RS18350	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
E8A47_RS18355	ENOG4107QSN	dihydrolipoamide acetyltransferase
E8A47_RS18360	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
E8A47_RS18365	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
E8A47_RS18370	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
E8A47_RS18380	ENOG4108R96	Methyltransferase, YaeB family
E8A47_RS18385	ENOG4105C8V	SAICAR synthetase
E8A47_RS18395	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
E8A47_RS18400	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E8A47_RS18410	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
E8A47_RS18415	ENOG4105ERG	peptidase m48, ste24p
E8A47_RS18420	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
E8A47_RS18435	ENOG4105FE9	pseudouridine synthase
E8A47_RS18440	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
E8A47_RS18445	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
E8A47_RS18450	ENOG4105CFI	type iii restriction protein res subunit
E8A47_RS18460	ENOG4108ETH	Formylglycinamide ribotide synthetase
E8A47_RS18465	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
E8A47_RS18470	ENOG4108Z6B	deaminase
E8A47_RS18475	ENOG4105C29	acyl-CoA thioesterase
E8A47_RS18480	ENOG4105C6K	Malic enzyme
E8A47_RS18485	ENOG4105VFB	Binds the 23S rRNA (By similarity)
E8A47_RS18490	ENOG4105C25	Primosomal protein n'
E8A47_RS18495	ENOG4105C75	arginyL-tRNA synthetase
E8A47_RS18505	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
E8A47_RS18510	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
E8A47_RS18530	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
E8A47_RS18535	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
E8A47_RS18540	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
E8A47_RS18545	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
E8A47_RS18555	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
E8A47_RS18560	ENOG4105D52	delta-aminolevulinic acid dehydratase
E8A47_RS18570	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
E8A47_RS18575	ENOG4105DZ2	Transcriptional regulator
E8A47_RS18580	ENOG4105JJR	Histidine kinase
E8A47_RS18585	ENOG4107EXC	regulatoR
E8A47_RS18595	ENOG4108WIW	Aspartyl protease
E8A47_RS18615	ENOG4105BZU	Histidine kinase
E8A47_RS18635	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
E8A47_RS18640	ENOG41080IJ	Diacylglycerol kinase
E8A47_RS18655	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
E8A47_RS18660	ENOG4107RX2	synthase
E8A47_RS18665	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
E8A47_RS18670	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
E8A47_RS18675	ENOG4107R73	Mate efflux family protein
E8A47_RS18680	ENOG4105CRW	Short chain fatty acid transporter
E8A47_RS18685	ENOG4108S4H	thioesterase Superfamily protein
E8A47_RS18695	ENOG4107SQD	Transcriptional regulator, GntR family
E8A47_RS18740	ENOG4105BZW	Glycerate kinase
E8A47_RS18745	ENOG4108RMU	ferritin dps family protein
E8A47_RS18750	ENOG4105CIN	aminoacyl-histidine dipeptidase
E8A47_RS18755	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
E8A47_RS18760	ENOG4105CH5	extracellular solute-binding protein, family 7
E8A47_RS18770	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E8A47_RS18775	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
E8A47_RS18780	ENOG4108UCS	ABC, transporter
E8A47_RS18785	ENOG4107QKW	extracellular solute-binding protein family 1
E8A47_RS18790	ENOG4108JJ8	(ABC) transporter
E8A47_RS18795	ENOG4108JJ9	ABC, transporter
E8A47_RS18805	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
E8A47_RS18810	ENOG4105C4M	(Ubiquinol oxidase) subunit I
E8A47_RS18815	ENOG4105C2M	dna polymerase I
E8A47_RS18825	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
E8A47_RS18830	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
E8A47_RS18835	ENOG4105EV8	ectoine hydroxylase
E8A47_RS18845	ENOG4105N14	lysine exporter protein LysE YggA
E8A47_RS18865	ENOG4108IV0	ABC, transporter
E8A47_RS18870	ENOG4105C0Z	ABC transporter
E8A47_RS18880	ENOG4105C32	Amino acid ABC transporter (Permease)
E8A47_RS18895	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
E8A47_RS18915	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
E8A47_RS18920	ENOG4105CEN	a g-specific adenine glycosylase
E8A47_RS18935	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
E8A47_RS18940	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
E8A47_RS18945	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
E8A47_RS18950	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
E8A47_RS18960	ENOG4105R2J	Conserved Protein
E8A47_RS18970	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
E8A47_RS18975	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
E8A47_RS18980	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
E8A47_RS18990	ENOG4105CIH	Imidazole acetol-phosphate transaminase
E8A47_RS19010	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
E8A47_RS19015	ENOG4108ZP8	Acetolactate synthase small subunit
E8A47_RS19020	ENOG4105C7K	acetolactate synthase
E8A47_RS19030	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
E8A47_RS19035	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
E8A47_RS19040	ENOG4105C34	Pseudouridine synthase
E8A47_RS19045	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E8A47_RS19050	ENOG4105C8Q	Methyl-accepting chemotaxis
E8A47_RS19055	ENOG4105BZU	Histidine kinase
E8A47_RS19060	ENOG4105C4K	Nad synthetase
E8A47_RS19070	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
E8A47_RS19080	ENOG4105C3M	thioredoxin reductase
E8A47_RS19085	ENOG4107QM5	aconitate hydratase
E8A47_RS19090	ENOG4107R1I	NAD-dependent malic enzyme
E8A47_RS19095	ENOG41066VF	YeeE YedE family protein
E8A47_RS19175	ENOG4105CS6	Rhs element vgr protein
E8A47_RS19205	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E8A47_RS19210	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
E8A47_RS19260	ENOG4108WC9	type VI secretion system effector, hcp1 family
E8A47_RS19265	ENOG4105C31	Tryptophanyl-tRNA synthetase
E8A47_RS19290	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
E8A47_RS19295	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
E8A47_RS19305	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
E8A47_RS19310	ENOG4105DTN	riboflavin biosynthesis protein ribF
E8A47_RS19315	ENOG4105CJR	Integral membrane protein (MviN
E8A47_RS19320	ENOG41082GY	Binds directly to 16S ribosomal RNA (By similarity)
E8A47_RS19330	ENOG4105CDA	abc transporter atp-binding protein
E8A47_RS19335	ENOG4105E5Q	amino acid AbC transporter
E8A47_RS19340	ENOG4105EAB	amino acid AbC transporter
E8A47_RS19365	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
E8A47_RS19380	ENOG4105DTS	flagellar hook-associated
E8A47_RS19385	ENOG4105DTS	flagellar hook-associated
E8A47_RS19390	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
E8A47_RS19420	ENOG4108TPP	exopolysaccharide synthesis
E8A47_RS19440	ENOG4105E3A	(ABC) transporter
E8A47_RS19445	ENOG4105DA5	(ABC) transporter
E8A47_RS19450	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
E8A47_RS19475	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
E8A47_RS19485	ENOG4105DRS	transport system, permease
E8A47_RS19495	ENOG4105XN3	extracellular solute-binding protein family 1
E8A47_RS19500	ENOG4105FGE	Short-chain dehydrogenase reductase Sdr
E8A47_RS19505	ENOG4105CIB	oxidoreductase Domain protein
E8A47_RS19515	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
E8A47_RS19520	ENOG4105CNN	ABC, transporter
E8A47_RS19530	ENOG4105E2R	ROK family
E8A47_RS19540	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
E8A47_RS19555	ENOG4105C2J	ABC transporter
E8A47_RS19565	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
E8A47_RS19590	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E8A47_RS19620	ENOG4105C0A	alcohol dehydrogenase
E8A47_RS19625	ENOG4105CTX	dehydratase
E8A47_RS19635	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
E8A47_RS19640	ENOG4105DG4	malate L-lactate dehydrogenase
E8A47_RS19645	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
E8A47_RS19670	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
E8A47_RS19675	ENOG4108QBF	Transcriptional regulator
E8A47_RS19680	ENOG4105DG4	malate L-lactate dehydrogenase
E8A47_RS19685	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E8A47_RS19690	ENOG4108K1J	Transporter DctQ
E8A47_RS19695	ENOG4108ERU	trap dicarboxylate transporter subunit DctP
E8A47_RS19710	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
E8A47_RS19720	ENOG4105DIA	mandelate racemase muconate lactonizing
E8A47_RS19725	ENOG4105CQB	FAD linked oxidase domain protein
E8A47_RS19730	ENOG4105CNV	Aldolase
E8A47_RS19735	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E8A47_RS19745	ENOG4105GQU	Trap dicarboxylate transporter, dctp subunit
E8A47_RS19750	ENOG4108W5M	transcriptional regulator
E8A47_RS19755	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
E8A47_RS19760	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
E8A47_RS19770	ENOG4105C7K	acetolactate synthase
E8A47_RS19775	ENOG4105DWD	nucleoside recognition domain protein
E8A47_RS19780	ENOG4105CYW	agmatinase
E8A47_RS19785	ENOG4108JUB	Transcriptional regulator
E8A47_RS19795	ENOG4105BZ7	extracellular solute-binding protein family 1
E8A47_RS19805	ENOG4105DRS	transport system, permease
E8A47_RS19820	ENOG4105C9U	ATP-dependent DNA helicase RecQ
E8A47_RS19840	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
E8A47_RS19845	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
E8A47_RS19850	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
E8A47_RS19870	ENOG4105KSC	Transcriptional regulator, TraR DksA family
E8A47_RS19885	ENOG4108I5D	sulfate abc transporter
E8A47_RS19895	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
E8A47_RS19905	ENOG4105DXI	Major Facilitator superfamily
E8A47_RS19910	ENOG4105ECQ	AraC Family Transcriptional Regulator
E8A47_RS19915	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
E8A47_RS19925	ENOG41085JF	Trap dicarboxylate transporter-dctp subunit
E8A47_RS19935	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E8A47_RS19945	ENOG4105CEY	Amp-dependent synthetase and ligase
E8A47_RS19975	ENOG4106032	Glutathionylspermidine synthase
E8A47_RS19980	ENOG4105C8Q	Methyl-accepting chemotaxis
E8A47_RS19985	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
E8A47_RS19990	ENOG4105BZU	Histidine kinase
E8A47_RS19995	ENOG4105CBS	Chea signal transduction histidine kinase
E8A47_RS20005	ENOG4105BZU	Histidine kinase
E8A47_RS20020	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
E8A47_RS20030	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E8A47_RS20035	ENOG41069H7	transport system small permease component
E8A47_RS20045	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
E8A47_RS20050	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
E8A47_RS20065	ENOG4105QAX	Iron-sulfur
E8A47_RS20070	ENOG4108IEG	Formate dehydrogenase Alpha subunit
E8A47_RS20100	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
E8A47_RS20105	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
E8A47_RS20110	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
E8A47_RS20115	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
E8A47_RS20120	ENOG4105CKI	cobalamin synthesis protein
E8A47_RS20125	ENOG4105BZU	Histidine kinase
E8A47_RS20130	ENOG4105EVZ	LysR family transcriptional regulator
E8A47_RS20135	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
E8A47_RS20145	ENOG4105CD3	dihydroorotase
E8A47_RS20150	ENOG4105BZ8	glutamate synthase
E8A47_RS20155	ENOG4107SJI	Dehydrogenase
E8A47_RS20165	ENOG4105C8Q	Methyl-accepting chemotaxis
E8A47_RS20185	ENOG4105E89	ABC transporter
E8A47_RS20195	ENOG4105BZU	Histidine kinase
E8A47_RS20200	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
E8A47_RS20205	ENOG4105DZC	cytosine deaminase
E8A47_RS20210	ENOG4108UIN	ybak prolyl-trna synthetase associated region
E8A47_RS20230	ENOG4105VE1	Phosphatidylcholine synthase
E8A47_RS20235	ENOG4108R3E	Dna-3-methyladenine glycosylase i
E8A47_RS20250	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
E8A47_RS20265	ENOG4105VN1	Heat shock protein
E8A47_RS20280	ENOG4105EIE	fructose-bisphosphate aldolase
E8A47_RS20285	ENOG4105EHG	Permease protein
E8A47_RS20290	ENOG4105E0A	ABC, transporter
E8A47_RS20310	ENOG4105EXG	Transcriptional regulator
E8A47_RS20335	ENOG410829K	Lysine exporter protein (Lyse ygga)
E8A47_RS20340	ENOG4105HKU	nucleoside recognition domain-containing protein
E8A47_RS20350	ENOG4108R86	Transcriptional regulator
E8A47_RS20355	ENOG4105C26	Dehydrogenase
E8A47_RS20360	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
E8A47_RS20365	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
E8A47_RS20370	ENOG4105CEY	Amp-dependent synthetase and ligase
E8A47_RS20375	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
E8A47_RS20380	ENOG4108IPT	Naphthoate synthase
E8A47_RS20385	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
E8A47_RS20395	ENOG4105E33	succinate dehydrogenase
E8A47_RS20410	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
E8A47_RS20415	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
E8A47_RS20420	ENOG4105E4F	Isochorismate synthase
E8A47_RS20430	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
E8A47_RS20435	ENOG4106EQQ	Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity)
E8A47_RS20450	ENOG4108JPW	Aminotransferase
E8A47_RS20455	ENOG4105C26	Dehydrogenase
E8A47_RS20460	ENOG4107QTZ	amino acid
E8A47_RS20465	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
E8A47_RS20485	ENOG4105DFD	Na H antiporter
E8A47_RS20490	ENOG4105C26	Dehydrogenase
E8A47_RS20495	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
E8A47_RS20500	ENOG4108Z86	Glutamine amidotransferase
E8A47_RS20505	ENOG4105CFQ	glutamine synthetase
E8A47_RS20510	ENOG4105CJP	fad dependent oxidoreductase
E8A47_RS20515	ENOG4105ENR	peptidase, M24
E8A47_RS20545	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
E8A47_RS20555	ENOG4107S6Z	Na H antiporter
E8A47_RS20565	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
E8A47_RS20570	ENOG4105C26	Dehydrogenase
E8A47_RS20590	ENOG4105C5H	ABC transporter
E8A47_RS20620	ENOG4105CSU	acyl-Coa dehydrogenase
E8A47_RS20635	ENOG4108ERU	trap dicarboxylate transporter subunit DctP
E8A47_RS20645	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E8A47_RS20660	ENOG4105GBT	ABC transporter
E8A47_RS20665	ENOG4105E5Q	amino acid AbC transporter
E8A47_RS20670	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
E8A47_RS20675	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
E8A47_RS20680	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
E8A47_RS20685	ENOG4105EMU	Dehydrogenase
E8A47_RS20690	ENOG4105BZS	acriflavin resistance protein
E8A47_RS20700	ENOG41060BG	Tetr family transcriptional regulator
E8A47_RS20705	ENOG4105ZXK	Dehydrogenase
E8A47_RS20710	ENOG4105C26	Dehydrogenase
E8A47_RS20715	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E8A47_RS20725	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
E8A47_RS20730	ENOG4105EXW	epimerase dehydratase
E8A47_RS20735	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
E8A47_RS20740	ENOG4105FB2	class II Aldolase
E8A47_RS20750	ENOG4105ZXK	Dehydrogenase
E8A47_RS20755	ENOG4105DIQ	Transcriptional regulator
E8A47_RS20770	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E8A47_RS20780	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
E8A47_RS20785	ENOG4105HDK	L-asparaginase
E8A47_RS20790	ENOG4105JXH	GntR family transcriptional regulator
E8A47_RS20795	ENOG4105CC0	LysR family Transcriptional regulator
E8A47_RS20805	ENOG4108YI3	3-hydroxyacyl-CoA-acyl carrier protein transferase
E8A47_RS20830	ENOG4107ENK	receptor
E8A47_RS20835	ENOG4106QJH	hemin transport protein
E8A47_RS20840	ENOG4107R4I	Periplasmic binding protein
E8A47_RS20845	ENOG4105EHG	Permease protein
E8A47_RS20855	ENOG4105WD1	Membrane
E8A47_RS20860	ENOG4105EW9	transcriptional regulator AsnC family
E8A47_RS20865	ENOG4105K6H	D-cysteine desulfhydrase
E8A47_RS20870	ENOG4105CJW	magnesium transporter
E8A47_RS20880	ENOG4105EMU	Dehydrogenase
E8A47_RS20905	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
E8A47_RS20915	ENOG4105C26	Dehydrogenase
E8A47_RS20925	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
E8A47_RS20930	ENOG4105D7K	pfkb domain protein
E8A47_RS20940	ENOG4105C2J	ABC transporter
E8A47_RS20955	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
E8A47_RS20965	ENOG4105DH8	myo-inositol catabolism
E8A47_RS20975	ENOG4105CS6	Rhs element vgr protein
E8A47_RS20995	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
E8A47_RS21000	ENOG4107STF	Involved in phosphonate degradation (By similarity)
E8A47_RS21010	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
E8A47_RS21015	ENOG4105C4Y	ABC transporter
E8A47_RS21020	ENOG4108K85	Transcriptional regulator
E8A47_RS21030	ENOG4105BZU	Histidine kinase
E8A47_RS21040	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E8A47_RS21055	ENOG4105C5Q	Transcriptional regulator
E8A47_RS21060	ENOG4105E7W	lamb ycsf family protein
E8A47_RS21065	ENOG4105P4J	Allophanate hydrolase, subunit 1
E8A47_RS21070	ENOG4107R7A	Allophanate hydrolase subunit 2
E8A47_RS21080	ENOG4105CK7	Sodium proline symporter
E8A47_RS21090	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
E8A47_RS21095	ENOG4108XHQ	(2Fe-2S)-binding domain protein
E8A47_RS21110	ENOG4105RE0	Asp Glu hydantoin racemase
E8A47_RS21115	ENOG4108UAU	isochorismatase
E8A47_RS21120	ENOG4108VHT	MarR family transcriptional regulator
E8A47_RS21125	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
E8A47_RS21140	ENOG4105C8Q	Methyl-accepting chemotaxis
E8A47_RS21170	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
E8A47_RS21175	ENOG4107SET	aldo keto reductase
E8A47_RS21180	ENOG4105BZ1	(ABC) transporter
E8A47_RS21185	ENOG4105EQW	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
E8A47_RS21210	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
E8A47_RS21215	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
E8A47_RS21225	ENOG4105CYW	agmatinase
E8A47_RS21235	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
E8A47_RS21240	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E8A47_RS21275	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
E8A47_RS21280	ENOG4105CKI	cobalamin synthesis protein
E8A47_RS21295	ENOG4105FAV	ABC, transporter
E8A47_RS21300	ENOG4105FDK	ABC transporter
E8A47_RS21315	ENOG4105C58	cytochrome c oxidase accessory protein ccog
E8A47_RS21320	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
E8A47_RS21325	ENOG4105C4M	(Ubiquinol oxidase) subunit I
E8A47_RS21330	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
E8A47_RS21340	ENOG4105EJQ	L-serine dehydratase
E8A47_RS21355	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
E8A47_RS21370	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
E8A47_RS21375	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
E8A47_RS21380	ENOG4105DVW	rieske (2Fe-2S)
E8A47_RS21395	ENOG4108IEG	Formate dehydrogenase Alpha subunit
E8A47_RS21405	ENOG4105E2A	Dehydrogenase
E8A47_RS21410	ENOG4105C94	Transporter
E8A47_RS21420	ENOG4107Y9U	Membrane
E8A47_RS21430	ENOG4105C10	Electron transfer flavoprotein
E8A47_RS21435	ENOG4105DF6	Fe-S oxidoreductase
E8A47_RS21450	ENOG4108IGT	Dipeptidase
E8A47_RS21455	ENOG4105ECQ	AraC Family Transcriptional Regulator
E8A47_RS21465	ENOG4108NIW	Leucine export protein LeuE
E8A47_RS21475	ENOG4107S6Z	Na H antiporter
E8A47_RS21495	ENOG4105D82	Glutamate dehydrogenase
E8A47_RS21500	ENOG4105NXH	GreA GreB family elongation factor
E8A47_RS21505	ENOG4105V9J	phenylacetic acid degradation operon negative regulatory protein
E8A47_RS21510	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
E8A47_RS21545	ENOG4105I7I	quinohemoprotein amine dehydrogenase gamma subunit
E8A47_RS21570	ENOG4108UKI	Enoyl-CoA hydratase
E8A47_RS21580	ENOG4108ZJI	phenylacetic acid degradation protein
E8A47_RS21585	ENOG4105DZS	Phenylacetate-CoA ligase
E8A47_RS21590	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
E8A47_RS21595	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
E8A47_RS21600	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
E8A47_RS21605	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
E8A47_RS21610	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
E8A47_RS21615	ENOG4105DXM	phenylacetic acid degradation protein
E8A47_RS21620	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E8A47_RS21635	ENOG4108ZT1	Transcriptional regulator
E8A47_RS21645	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
E8A47_RS21655	ENOG4105F1J	Homogentisate 1,2-dioxygenase
E8A47_RS21665	ENOG4108RXX	maleylacetoacetate isomerase
E8A47_RS21670	ENOG4105C2C	drug resistance transporter, Bcr CflA
E8A47_RS21685	ENOG4105C8J	)-transporter
E8A47_RS21690	ENOG4108JU8	Transcriptional regulator
E8A47_RS21695	ENOG4105F7P	transcriptional regulator AsnC family
E8A47_RS21700	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
E8A47_RS21725	ENOG41079YP	Citrate utilization protein b
E8A47_RS21730	ENOG4107EFR	Flavocytochrome c
E8A47_RS21740	ENOG4105C26	Dehydrogenase
E8A47_RS21755	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
E8A47_RS21760	ENOG4108TY5	Exhibits lactonase activity. Acts in cells with perturbed membrane integrity and is possibly related to the membrane homeostasis
E8A47_RS21770	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E8A47_RS21805	ENOG4105EXG	Transcriptional regulator
E8A47_RS21920	ENOG4107ZQN	disulfide bond
E8A47_RS21925	ENOG4105PGM	cation diffusion facilitator family transporter
E8A47_RS21930	ENOG4105BZU	Histidine kinase
E8A47_RS21935	ENOG4105D44	asparaginase
E8A47_RS21940	ENOG4105CDA	abc transporter atp-binding protein
E8A47_RS21945	ENOG4105DRP	amino acid AbC transporter
E8A47_RS21950	ENOG4105EZ7	amino acid ABC transporter
E8A47_RS21960	ENOG4105DND	Transcriptional regulator
E8A47_RS21965	ENOG4105CMM	transposase
E8A47_RS21985	ENOG4105FFA	Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin (By similarity)
E8A47_RS21990	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
E8A47_RS21995	ENOG4107QSN	dihydrolipoamide acetyltransferase
E8A47_RS22005	ENOG4105CA9	Pyruvate kinase
E8A47_RS22015	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
E8A47_RS22020	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
E8A47_RS22025	ENOG41060W2	glyoxylate carboligase
E8A47_RS22030	ENOG4105S0E	allantoin catabolism protein
E8A47_RS22035	ENOG4108FUF	Transcriptional regulator, IclR family
E8A47_RS22060	ENOG4105C8Q	Methyl-accepting chemotaxis
E8A47_RS22065	ENOG4105IW1	AmiS UreI transporter
E8A47_RS22075	ENOG4108JQ1	Dehydrogenase
E8A47_RS22080	ENOG4105JSC	dimethylmenaquinone methyltransferase
E8A47_RS22100	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E8A47_RS22115	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
E8A47_RS22120	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
E8A47_RS22160	ENOG4108K85	Transcriptional regulator
E8A47_RS22165	ENOG4105J76	Periplasmic binding protein
E8A47_RS22205	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
E8A47_RS22215	ENOG4105CQB	FAD linked oxidase domain protein
E8A47_RS22220	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
E8A47_RS22225	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
E8A47_RS22230	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E8A47_RS22235	ENOG4105ECQ	AraC Family Transcriptional Regulator
E8A47_RS22250	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E8A47_RS22265	ENOG4107QIZ	NADH dehydrogenase
E8A47_RS22270	ENOG4108IEG	Formate dehydrogenase Alpha subunit
E8A47_RS22275	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
E8A47_RS22290	ENOG4107S2Z	UPF0761 membrane protein
E8A47_RS22295	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
E8A47_RS22300	ENOG4105IY8	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
E8A47_RS22305	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
E8A47_RS22310	ENOG4105CQM	Urea amidohydrolase subunit alpha
E8A47_RS22315	ENOG4105KI2	Urea amidohydrolase subunit beta
E8A47_RS22320	ENOG4108YZ9	Urea amidohydrolase subunit gamma
E8A47_RS22325	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
E8A47_RS22330	ENOG4105BZU	Histidine kinase
E8A47_RS22335	ENOG4105DSE	periplasmic solute binding protein
E8A47_RS22340	ENOG4105DIK	(ABC) transporter
E8A47_RS22345	ENOG4105CC5	ABC transporter
E8A47_RS22350	ENOG4105CC5	ABC transporter
E8A47_RS22355	ENOG4108IV0	ABC, transporter
E8A47_RS22360	ENOG4105C0Z	ABC transporter
E8A47_RS22370	ENOG4105C32	Amino acid ABC transporter (Permease)
E8A47_RS22395	ENOG4108V9W	transcriptional regulatory protein
E8A47_RS22400	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
E8A47_RS22410	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
E8A47_RS22415	ENOG4105D7T	ABC transporter
E8A47_RS22430	ENOG4105ETT	transcriptional Regulator, LysR family
E8A47_RS22435	ENOG4105C26	Dehydrogenase
E8A47_RS22440	ENOG4105DFD	Na H antiporter
E8A47_RS22445	ENOG4105CJP	fad dependent oxidoreductase
E8A47_RS22450	ENOG4105E32	cytoplasmic protein
E8A47_RS22455	ENOG4105CQB	FAD linked oxidase domain protein
E8A47_RS22460	ENOG4108JPW	Aminotransferase
E8A47_RS22465	ENOG4105ETT	transcriptional Regulator, LysR family
E8A47_RS22475	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E8A47_RS22485	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
E8A47_RS22510	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
E8A47_RS22515	ENOG410642E	Short chain dehydrogenase
E8A47_RS22520	ENOG4105D8X	mechanosensitive ion channel
E8A47_RS22525	ENOG4105W39	Membrane
E8A47_RS22540	ENOG4105C72	UPF0176 protein
E8A47_RS22550	ENOG4108JQ1	Dehydrogenase
E8A47_RS22555	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
E8A47_RS22560	ENOG4105CTB	Polyprenyl synthetase
E8A47_RS22565	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
E8A47_RS22570	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
E8A47_RS22590	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
E8A47_RS22595	ENOG4108UT2	hemolysin iii
E8A47_RS22600	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
E8A47_RS22605	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
E8A47_RS22610	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
E8A47_RS22620	ENOG4105EZ7	amino acid ABC transporter
E8A47_RS22625	ENOG4105DRP	amino acid AbC transporter
E8A47_RS22630	ENOG4105CDA	abc transporter atp-binding protein
E8A47_RS22640	ENOG4105BZU	Histidine kinase
E8A47_RS22660	ENOG4105S7S	phosphonate abc transporter
E8A47_RS22675	ENOG4105C8Q	Methyl-accepting chemotaxis
E8A47_RS22680	ENOG4105C8Q	Methyl-accepting chemotaxis
E8A47_RS22685	ENOG4105DUM	transcriptional regulator, lysR family
E8A47_RS22690	ENOG4105DP0	ferredoxin-NADP reductase
E8A47_RS22695	ENOG4108YZA	Nitrogen regulatory protein pii
E8A47_RS22705	ENOG4108YZA	Nitrogen regulatory protein pii
E8A47_RS22710	ENOG4105W0Z	cytoplasmic protein
E8A47_RS22730	ENOG4105J76	Periplasmic binding protein
E8A47_RS22740	ENOG4105ZEG	Suppressor protein
E8A47_RS22760	ENOG4105W1Y	Transcriptional regulator
E8A47_RS22775	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
E8A47_RS22815	ENOG4108YYH	Nadph-dependent fmn reductase
E8A47_RS22830	ENOG4105CS1	NAD(P)H quinone oxidoreductase
E8A47_RS22835	ENOG4105CC0	LysR family Transcriptional regulator
E8A47_RS22845	ENOG4107QP3	malate synthase g
E8A47_RS22860	ENOG4105DHQ	Histidine kinase
E8A47_RS22865	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
E8A47_RS22870	ENOG4105DKP	glycosyl transferase, family 9
E8A47_RS22875	ENOG41080IJ	Diacylglycerol kinase
E8A47_RS22885	ENOG4105DIJ	Phosphoethanolamine transferase
E8A47_RS22890	ENOG4105M08	Membrane
E8A47_RS22895	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
E8A47_RS22905	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
E8A47_RS22940	ENOG4105C5I	Dehydrogenase
E8A47_RS22960	ENOG4108ZX6	Electron transport protein SCO1 SenC
E8A47_RS22970	ENOG4108V1T	peptidylprolyl cis-trans isomerase
E8A47_RS22975	ENOG41080TK	Universal stress protein
E8A47_RS22980	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E8A47_RS22985	ENOG4108K1J	Transporter DctQ
E8A47_RS22990	ENOG4108KJ1	Trap dicarboxylate transporter, dctp subunit
E8A47_RS23000	ENOG4105C5H	ABC transporter
E8A47_RS23005	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
E8A47_RS23015	ENOG4105DWF	phosphomethylpyrimidine kinase
E8A47_RS23020	ENOG4105CH5	extracellular solute-binding protein, family 7
E8A47_RS23025	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E8A47_RS23040	ENOG4108Z33	Thiol disulfide Interchange Protein
E8A47_RS23045	ENOG4106RE7	Cytochrome
E8A47_RS23050	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
E8A47_RS23055	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
E8A47_RS23060	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
E8A47_RS23070	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
E8A47_RS23075	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
E8A47_RS23080	ENOG4105CH7	arginosuccinase
E8A47_RS23085	ENOG4105BZU	Histidine kinase
E8A47_RS23090	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
E8A47_RS23110	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
E8A47_RS23115	ENOG4108KB2	LysR family Transcriptional regulator
E8A47_RS23125	ENOG4105NN7	muconolactone delta-isomerase
E8A47_RS23130	ENOG4105DTQ	mandelate racemase muconate lactonizing
E8A47_RS23135	ENOG4105DE9	3-keto-5-aminohexanoate cleavage enzyme
E8A47_RS23140	ENOG4105C8P	)-transporter
E8A47_RS23145	ENOG4105K56	Transcriptional regulator
E8A47_RS23155	ENOG4105RD8	TRAP dicarboxylate transporter
E8A47_RS23160	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
E8A47_RS23175	ENOG4105C26	Dehydrogenase
E8A47_RS23180	ENOG4108K3Z	AraC family transcriptional regulator
E8A47_RS23190	ENOG4105C8Q	Methyl-accepting chemotaxis
E8A47_RS23215	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
E8A47_RS23245	ENOG4105CH5	extracellular solute-binding protein, family 7
E8A47_RS23250	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E8A47_RS23265	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
E8A47_RS23275	ENOG4108Q89	anthranilate 1,2-dioxygenase large subunit
E8A47_RS23290	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
E8A47_RS23295	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E8A47_RS23310	ENOG41072AC	4-hydroxybenzoate 3-monooxygenase
E8A47_RS23320	ENOG4105F04	LysR family Transcriptional regulator
E8A47_RS23325	ENOG4105C7F	AcnD-accessory protein PrpF
E8A47_RS23345	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E8A47_RS23355	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
E8A47_RS23365	ENOG4108NDG	TRAP dicarboxylate
E8A47_RS23370	ENOG4105FP9	thiamine pyrophosphate
E8A47_RS23380	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
E8A47_RS23385	ENOG4105RD8	TRAP dicarboxylate transporter
E8A47_RS23395	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
E8A47_RS23400	ENOG4108ERU	trap dicarboxylate transporter subunit DctP
E8A47_RS23410	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E8A47_RS23425	ENOG4105E4E	Thioester reductase domain-containing protein
E8A47_RS23435	ENOG4108WYP	Transcriptional regulator
E8A47_RS23450	ENOG4108NDG	TRAP dicarboxylate
E8A47_RS23505	ENOG4105CS6	Rhs element vgr protein
E8A47_RS23515	ENOG4105RM9	Protocatechuate 3,4-dioxygenase alpha
E8A47_RS23520	ENOG4105EU7	Protocatechuate 3,4-dioxygenase, beta
E8A47_RS23525	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
E8A47_RS23530	ENOG4105CHU	acetyl-coa acetyltransferase
E8A47_RS23545	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
E8A47_RS23555	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
E8A47_RS23565	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E8A47_RS23575	ENOG4105E2X	shikimate dehydrogenase
E8A47_RS23580	ENOG4105DRR	Transcriptional regulator, GntR family
E8A47_RS23595	ENOG4108KEZ	Dehydrogenase
E8A47_RS23600	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
E8A47_RS23605	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E8A47_RS23610	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
E8A47_RS23645	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
E8A47_RS23655	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E8A47_RS23670	ENOG4106517	Short-chain dehydrogenase reductase Sdr
E8A47_RS23685	ENOG4105RK9	auxin efflux carrier
E8A47_RS23690	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
E8A47_RS23710	ENOG4107HP6	Transcriptional regulator
E8A47_RS23720	ENOG4105E32	cytoplasmic protein
E8A47_RS23725	ENOG41081XQ	Conserved Protein
E8A47_RS23730	ENOG4105C8J	)-transporter
E8A47_RS23740	ENOG4106KNT	transcriptional regulator
E8A47_RS23745	ENOG4105C4R	Atp-dependent dna helicase
E8A47_RS23750	ENOG4105CH5	extracellular solute-binding protein, family 7
E8A47_RS23755	ENOG4105NAU	thioesterase Superfamily protein
E8A47_RS23760	ENOG4105DJH	phosphate
E8A47_RS23765	ENOG4105C8U	phosphate abc transporter
E8A47_RS23770	ENOG4105E2Z	phosphate ABC transporter (Permease
E8A47_RS23775	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
E8A47_RS23780	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
E8A47_RS23810	ENOG4105BZU	Histidine kinase
E8A47_RS23815	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
E8A47_RS23820	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
E8A47_RS23825	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
E8A47_RS23830	ENOG4107QZF	nitrite reductase NADPH large subunit
E8A47_RS23835	ENOG4105NYX	DNA-binding protein
E8A47_RS23845	ENOG41090KR	LysR family transcriptional Regulator
E8A47_RS23875	ENOG4105EM2	membrane
E8A47_RS23880	ENOG4105CB5	ATP-dependent DNA helicase recG
E8A47_RS23885	ENOG4105C5Q	Transcriptional regulator
E8A47_RS23895	ENOG4105KME	endoribonuclease L-psp
E8A47_RS23900	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
E8A47_RS23905	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
E8A47_RS23910	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
E8A47_RS23925	ENOG4105F27	Major Facilitator
E8A47_RS23945	ENOG4105EUB	pirin domain protein
E8A47_RS23965	ENOG4105HF0	Membrane
E8A47_RS23985	ENOG4105DSJ	YicC domain protein
E8A47_RS24000	ENOG4105C2J	ABC transporter
E8A47_RS24005	ENOG4105CNN	ABC, transporter
E8A47_RS24010	ENOG4105F5R	ABC transporter
E8A47_RS24015	ENOG4105CMG	Carbohydrate kinase
E8A47_RS24030	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
E8A47_RS24040	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
E8A47_RS24045	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
E8A47_RS24050	ENOG4105C4R	Atp-dependent dna helicase
E8A47_RS24060	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
E8A47_RS24065	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
E8A47_RS24080	ENOG4105DN9	Na H antiporter
E8A47_RS24085	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
E8A47_RS24090	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
E8A47_RS24100	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
E8A47_RS24110	ENOG4105CJW	magnesium transporter
E8A47_RS24115	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
E8A47_RS24120	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
E8A47_RS24125	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
E8A47_RS24130	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
E8A47_RS24135	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
E8A47_RS24140	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
E8A47_RS24145	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
E8A47_RS24150	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
E8A47_RS24160	ENOG4105FA0	parb-like partition protein
E8A47_RS24165	ENOG4107QJE	Chromosome Partitioning Protein
E8A47_RS24170	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
E8A47_RS24175	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
E8A47_RS24185	ENOG4105E5Q	amino acid AbC transporter
E8A47_RS24190	ENOG4107R0W	ABC transporter
E8A47_RS24195	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
E8A47_RS24200	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
E8A47_RS24210	ENOG4108YXA	Membrane
E8A47_RS24220	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
E8A47_RS24240	ENOG4105P8Q	Curli production assembly transport component CsgG
E8A47_RS24255	ENOG41086KC	Transcriptional regulator
E8A47_RS24260	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
E8A47_RS24265	ENOG4105CSA	Coproporphyrinogen iii oxidase
E8A47_RS24270	ENOG4108ZG0	Ompa motb domain protein
E8A47_RS24275	ENOG4105D6S	protein involved in catabolism of external DNA
E8A47_RS24280	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
E8A47_RS24285	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
E8A47_RS24290	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
E8A47_RS24295	ENOG4105VG0	50S ribosomal protein l34