locus-tag	class	description
DOM78_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DOM78_RS00015	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DOM78_RS00020	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DOM78_RS00025	COG0300	oxidoreductase activity
DOM78_RS00040	COG2855	membrane
DOM78_RS00060	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DOM78_RS00065	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DOM78_RS00070	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DOM78_RS00080	COG1028	Short-chain dehydrogenase reductase Sdr
DOM78_RS00085	COG3959	Transketolase, thiamine diphosphate binding domain
DOM78_RS00090	COG3958	Transketolase
DOM78_RS00100	COG0318	PFAM AMP-dependent synthetase and ligase
DOM78_RS00175	COG1064	alcohol dehydrogenase
DOM78_RS00190	COG0730	response to heat
DOM78_RS00200	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DOM78_RS00205	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DOM78_RS00250	COG4771	TonB-dependent receptor
DOM78_RS00255	COG1419	protein localization to endoplasmic reticulum
DOM78_RS00260	COG0455	bacterial-type flagellum organization
DOM78_RS00270	COG1191	sigma factor activity
DOM78_RS00275	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DOM78_RS00280	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DOM78_RS00280	COG1776	CheC inhibitor of MCP methylation
DOM78_RS00285	COG0492	ferredoxin-NADP+ reductase activity
DOM78_RS00295	COG0840	transmembrane signaling receptor activity
DOM78_RS00310	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DOM78_RS00320	COG1271	oxidase subunit
DOM78_RS00325	COG1294	oxidase, subunit
DOM78_RS00330	COG0814	amino acid
DOM78_RS00335	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DOM78_RS00345	COG2189	Belongs to the N(4) N(6)-methyltransferase family
DOM78_RS00375	COG2217	Heavy metal translocating P-type atpase
DOM78_RS00380	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DOM78_RS00385	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DOM78_RS00390	COG0746	molybdenum cofactor guanylyltransferase activity
DOM78_RS00395	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DOM78_RS00405	COG0850	regulation of cytokinetic process
DOM78_RS00410	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
DOM78_RS00420	COG0083	homoserine kinase activity
DOM78_RS00430	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DOM78_RS00440	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DOM78_RS00445	COG1663	tetraacyldisaccharide 4'-kinase activity
DOM78_RS00450	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DOM78_RS00455	COG0723	plastoquinol--plastocyanin reductase activity
DOM78_RS00460	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DOM78_RS00470	COG2353	YceI-like domain
DOM78_RS00475	COG1136	(ABC) transporter
DOM78_RS00485	COG1696	Membrane protein involved in D-alanine export
DOM78_RS00510	COG4786	Flagellar basal body rod
DOM78_RS00515	COG2860	membrane
DOM78_RS00520	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DOM78_RS00525	COG0802	atpase or kinase
DOM78_RS00530	COG1137	ATPase activity
DOM78_RS00535	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DOM78_RS00550	COG0052	Belongs to the universal ribosomal protein uS2 family
DOM78_RS00555	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DOM78_RS00560	COG0367	asparagine synthase
DOM78_RS00590	COG1696	Membrane protein involved in D-alanine export
DOM78_RS00600	COG1696	Membrane protein involved in D-alanine export
DOM78_RS00605	COG0281	malic enzyme
DOM78_RS00605	COG0280	phosphate acetyltransferase
DOM78_RS00610	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DOM78_RS00615	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DOM78_RS00625	COG4786	Flagellar basal body rod
DOM78_RS00635	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DOM78_RS00635	COG1333	cytochrome c biogenesis protein
DOM78_RS00645	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DOM78_RS00655	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DOM78_RS00660	COG0287	Prephenate dehydrogenase
DOM78_RS00665	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DOM78_RS00670	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DOM78_RS00675	COG0612	Peptidase, M16
DOM78_RS00715	COG0134	indole-3-glycerol-phosphate synthase activity
DOM78_RS00720	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DOM78_RS00770	COG0438	transferase activity, transferring glycosyl groups
DOM78_RS00775	COG1216	Glycosyl transferase, family 2
DOM78_RS00790	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DOM78_RS00800	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DOM78_RS00805	COG0247	lactate metabolic process
DOM78_RS00825	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DOM78_RS00830	COG1338	Plays a role in the flagellum-specific transport system
DOM78_RS00835	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DOM78_RS00850	COG0328	RNA-DNA hybrid ribonuclease activity
DOM78_RS00855	COG0571	ribonuclease III activity
DOM78_RS00860	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DOM78_RS00865	COG0154	amidase activity
DOM78_RS00870	COG0516	GMP reductase activity
DOM78_RS00870	COG0517	IMP dehydrogenase activity
DOM78_RS00890	COG0587	DNA-directed DNA polymerase activity
DOM78_RS00895	COG0195	Participates in both transcription termination and antitermination
DOM78_RS00900	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DOM78_RS00905	COG0006	proline dipeptidase activity
DOM78_RS00920	COG0335	large ribosomal subunit rRNA binding
DOM78_RS00925	COG0336	Belongs to the RNA methyltransferase TrmD family
DOM78_RS00940	COG0228	four-way junction DNA binding
DOM78_RS00945	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DOM78_RS00950	COG0735	belongs to the Fur family
DOM78_RS00960	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DOM78_RS00965	COG0525	valine-tRNA ligase activity
DOM78_RS00970	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
DOM78_RS00990	COG0727	PFAM Uncharacterised protein family (UPF0153)
DOM78_RS01005	COG0708	Exodeoxyribonuclease III
DOM78_RS01025	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DOM78_RS01030	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DOM78_RS01035	COG3585	molybdate ion transport
DOM78_RS01050	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DOM78_RS01065	COG1058	Belongs to the CinA family
DOM78_RS01065	COG1546	Belongs to the CinA family
DOM78_RS01090	COG1420	regulation of RNA biosynthetic process
DOM78_RS01095	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DOM78_RS01105	COG0443	Heat shock 70 kDa protein
DOM78_RS01110	COG0252	asparaginase activity
DOM78_RS01115	COG3069	C4-dicarboxylate transmembrane transporter activity
DOM78_RS01120	COG0753	catalase activity
DOM78_RS01130	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DOM78_RS01175	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
DOM78_RS01185	COG4771	TonB-dependent receptor
DOM78_RS01190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DOM78_RS01195	COG1120	ATPase activity
DOM78_RS01305	COG0673	inositol 2-dehydrogenase activity
DOM78_RS01315	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DOM78_RS01330	COG0148	phosphopyruvate hydratase activity
DOM78_RS01335	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DOM78_RS01340	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
DOM78_RS01345	COG0628	permease
DOM78_RS01355	COG2192	nodulation
DOM78_RS01375	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
DOM78_RS01380	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DOM78_RS01390	COG1519	Transferase
DOM78_RS01395	COG0564	pseudouridine synthase activity
DOM78_RS01435	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DOM78_RS01450	COG0527	aspartate kinase activity
DOM78_RS01455	COG0494	nUDIX hydrolase
DOM78_RS01460	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DOM78_RS01465	COG0438	transferase activity, transferring glycosyl groups
DOM78_RS01505	COG1487	ribonuclease activity
DOM78_RS01525	COG0826	peptidase U32
DOM78_RS01530	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
DOM78_RS01555	COG1556	Lactate utilization protein
DOM78_RS01560	COG1139	Iron-sulfur cluster binding protein
DOM78_RS01565	COG0247	lactate metabolic process
DOM78_RS01580	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DOM78_RS01590	COG1233	COG1233 Phytoene dehydrogenase and related
DOM78_RS01610	COG0438	transferase activity, transferring glycosyl groups
DOM78_RS01650	COG1487	ribonuclease activity
DOM78_RS01670	COG0826	peptidase U32
DOM78_RS01675	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
DOM78_RS01700	COG1556	Lactate utilization protein
DOM78_RS01705	COG1139	Iron-sulfur cluster binding protein
DOM78_RS01710	COG0247	lactate metabolic process
DOM78_RS01725	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DOM78_RS01735	COG1233	COG1233 Phytoene dehydrogenase and related
DOM78_RS01755	COG1216	Glycosyl transferase, family 2
DOM78_RS01765	COG0418	dihydroorotase activity
DOM78_RS01775	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DOM78_RS01785	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DOM78_RS01795	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DOM78_RS01805	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DOM78_RS01810	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DOM78_RS01815	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DOM78_RS01830	COG0101	tRNA pseudouridine synthase activity
DOM78_RS01855	COG1185	polyribonucleotide nucleotidyltransferase activity
DOM78_RS01860	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DOM78_RS01875	COG1757	Na H antiporter
DOM78_RS01880	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DOM78_RS01885	COG0552	protein localization to endoplasmic reticulum
DOM78_RS01900	COG1418	mRNA catabolic process
DOM78_RS01915	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DOM78_RS01925	COG0784	Response regulator, receiver
DOM78_RS01925	COG0835	chemotaxis
DOM78_RS01930	COG1183	phosphatidylcholine synthase activity
DOM78_RS01940	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DOM78_RS01945	COG2264	protein methyltransferase activity
DOM78_RS01950	COG0745	RESPONSE REGULATOR receiver
DOM78_RS01955	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DOM78_RS01975	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DOM78_RS01985	COG1758	RNA polymerase activity
DOM78_RS01990	COG0528	UMP kinase activity
DOM78_RS02000	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DOM78_RS02005	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DOM78_RS02005	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DOM78_RS02010	COG0779	Required for maturation of 30S ribosomal subunits
DOM78_RS02015	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DOM78_RS02020	COG0343	queuine tRNA-ribosyltransferase activity
DOM78_RS02025	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DOM78_RS02030	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
DOM78_RS02035	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DOM78_RS02040	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DOM78_RS02055	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DOM78_RS02080	COG0129	dihydroxy-acid dehydratase activity
DOM78_RS02095	COG0174	glutamine synthetase
DOM78_RS02100	COG0574	Belongs to the PEP-utilizing enzyme family
DOM78_RS02100	COG3848	Pyruvate phosphate dikinase
DOM78_RS02110	COG0180	Tryptophanyl-tRNA synthetase
DOM78_RS02115	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DOM78_RS02125	COG0674	pyruvate-flavodoxin oxidoreductase activity
DOM78_RS02130	COG1013	pyruvate-flavodoxin oxidoreductase activity
DOM78_RS02135	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DOM78_RS02145	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DOM78_RS02155	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DOM78_RS02160	COG0629	single-stranded DNA binding
DOM78_RS02165	COG0360	Binds together with S18 to 16S ribosomal RNA
DOM78_RS02170	COG1466	dna polymerase III delta subunit
DOM78_RS02175	COG0557	exoribonuclease II activity
DOM78_RS02190	COG0752	glycyl-tRNA synthetase alpha subunit
DOM78_RS02205	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DOM78_RS02210	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DOM78_RS02225	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DOM78_RS02250	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DOM78_RS02270	COG1937	Protein conserved in bacteria
DOM78_RS02275	COG0606	chelatase, subunit chli
DOM78_RS02280	COG0242	peptide deformylase activity
DOM78_RS02290	COG0740	serine-type endopeptidase activity
DOM78_RS02295	COG0544	peptidyl-prolyl cis-trans isomerase activity
DOM78_RS02300	COG1157	protein secretion by the type III secretion system
DOM78_RS02305	COG0840	transmembrane signaling receptor activity
DOM78_RS02310	COG2050	protein possibly involved in aromatic compounds catabolism
DOM78_RS02310	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
DOM78_RS02315	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DOM78_RS02325	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DOM78_RS02325	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DOM78_RS02335	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
DOM78_RS02345	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DOM78_RS02350	COG2176	DNA-directed DNA polymerase activity
DOM78_RS02355	COG2890	protein-(glutamine-N5) methyltransferase activity
DOM78_RS02360	COG0501	Belongs to the peptidase M48B family
DOM78_RS02365	COG0504	CTP synthase activity
DOM78_RS02375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DOM78_RS02380	COG0825	malonyl-CoA metabolic process
DOM78_RS02385	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DOM78_RS02390	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DOM78_RS02395	COG1028	Short-chain dehydrogenase reductase Sdr
DOM78_RS02400	COG4953	penicillin-binding protein 1C
DOM78_RS02405	COG2373	Large extracellular alpha-helical protein
DOM78_RS02410	COG0564	pseudouridine synthase activity
DOM78_RS02430	COG0573	inorganic phosphate transmembrane transporter activity
DOM78_RS02435	COG0581	inorganic phosphate transmembrane transporter activity
DOM78_RS02440	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DOM78_RS02455	COG5002	protein histidine kinase activity
DOM78_RS02485	COG0471	metal ion transport
DOM78_RS02495	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DOM78_RS02515	COG0372	Belongs to the citrate synthase family
DOM78_RS02520	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DOM78_RS02525	COG0193	aminoacyl-tRNA hydrolase activity
DOM78_RS02535	COG0356	it plays a direct role in the translocation of protons across the membrane
DOM78_RS02540	COG0352	thiamine-phosphate diphosphorylase activity
DOM78_RS02580	COG0489	protein tyrosine kinase activity
DOM78_RS02595	COG0019	diaminopimelate decarboxylase activity
DOM78_RS02600	COG0077	Prephenate dehydratase
DOM78_RS02600	COG1605	Chorismate mutase
DOM78_RS02615	COG2267	carboxylic ester hydrolase activity
DOM78_RS02625	COG1960	acyl-CoA dehydrogenase activity
DOM78_RS02635	COG0585	pseudouridine synthase activity
DOM78_RS02640	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DOM78_RS02655	COG0484	heat shock protein binding
DOM78_RS02665	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
DOM78_RS02670	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DOM78_RS02670	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DOM78_RS02675	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DOM78_RS02680	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DOM78_RS02700	COG0450	alkyl hydroperoxide reductase
DOM78_RS02705	COG3162	membrane
DOM78_RS02710	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DOM78_RS02720	COG0556	nucleotide-excision repair
DOM78_RS02735	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DOM78_RS02750	COG0736	holo-[acyl-carrier-protein] synthase activity
DOM78_RS02755	COG0799	negative regulation of ribosome biogenesis
DOM78_RS02760	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DOM78_RS02765	COG0864	Transcriptional regulator
DOM78_RS02770	COG0811	peptide transport
DOM78_RS02775	COG0848	biopolymer transport protein
DOM78_RS02785	COG1126	abc transporter atp-binding protein
DOM78_RS02790	COG0765	amino acid transport
DOM78_RS02825	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DOM78_RS02830	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
DOM78_RS02835	COG0142	geranyltranstransferase activity
DOM78_RS02845	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DOM78_RS02850	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DOM78_RS02885	COG2833	Protein of unknown function (DUF455)
DOM78_RS02895	COG0126	phosphoglycerate kinase activity
DOM78_RS02930	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DOM78_RS02935	COG0298	carbon dioxide binding
DOM78_RS02945	COG0409	Hydrogenase expression formation protein
DOM78_RS02955	COG0309	Hydrogenase expression formation protein (HypE)
DOM78_RS02960	COG0724	RNA recognition motif
DOM78_RS02970	COG0653	protein targeting
DOM78_RS02975	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DOM78_RS02985	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DOM78_RS02985	COG0512	Glutamine amidotransferase of anthranilate synthase
DOM78_RS02995	COG0359	binds to the 23S rRNA
DOM78_RS03000	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DOM78_RS03005	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DOM78_RS03020	COG0318	PFAM AMP-dependent synthetase and ligase
DOM78_RS03020	COG0204	Acyl-transferase
DOM78_RS03025	COG0051	transcription antitermination factor activity, RNA binding
DOM78_RS03030	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DOM78_RS03035	COG0088	Forms part of the polypeptide exit tunnel
DOM78_RS03040	COG0089	rRNA binding
DOM78_RS03045	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DOM78_RS03050	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DOM78_RS03055	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DOM78_RS03060	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DOM78_RS03065	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DOM78_RS03070	COG0255	Belongs to the universal ribosomal protein uL29 family
DOM78_RS03075	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DOM78_RS03080	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DOM78_RS03085	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DOM78_RS03090	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DOM78_RS03095	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DOM78_RS03100	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DOM78_RS03105	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DOM78_RS03110	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DOM78_RS03115	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DOM78_RS03120	COG0200	Binds to the 23S rRNA
DOM78_RS03125	COG0201	protein transport
DOM78_RS03130	COG0024	Methionine aminopeptidase
DOM78_RS03135	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DOM78_RS03145	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DOM78_RS03150	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DOM78_RS03155	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DOM78_RS03160	COG0202	RNA polymerase activity
DOM78_RS03165	COG0203	ribosomal protein L17
DOM78_RS03170	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DOM78_RS03200	COG3383	formate dehydrogenase (NAD+) activity
DOM78_RS03205	COG0437	4 iron, 4 sulfur cluster binding
DOM78_RS03215	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DOM78_RS03225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DOM78_RS03245	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DOM78_RS03255	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
DOM78_RS03305	COG0783	Belongs to the Dps family
DOM78_RS03310	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DOM78_RS03330	COG1215	transferase activity, transferring glycosyl groups
DOM78_RS03340	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DOM78_RS03350	COG1007	ATP synthesis coupled electron transport
DOM78_RS03360	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DOM78_RS03365	COG0713	ATP synthesis coupled electron transport
DOM78_RS03370	COG0839	Belongs to the complex I subunit 6 family
DOM78_RS03375	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DOM78_RS03380	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DOM78_RS03400	COG0649	NAD binding
DOM78_RS03405	COG0649	NAD binding
DOM78_RS03410	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DOM78_RS03425	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DOM78_RS03435	COG1160	GTP binding
DOM78_RS03450	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DOM78_RS03450	COG0140	phosphoribosyl-ATP diphosphatase activity
DOM78_RS03455	COG0330	HflC and HflK could
DOM78_RS03465	COG0488	(ABC) transporter
DOM78_RS03475	COG1674	ftsk spoiiie
DOM78_RS03490	COG2201	protein-glutamate methylesterase activity
DOM78_RS03520	COG0357	Ribosomal RNA small subunit methyltransferase G
DOM78_RS03525	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DOM78_RS03530	COG0805	protein transport
DOM78_RS03535	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DOM78_RS03540	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DOM78_RS03550	COG1408	metallophosphoesterase
DOM78_RS03555	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DOM78_RS03560	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DOM78_RS03565	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DOM78_RS03570	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DOM78_RS03575	COG0233	cytoplasmic translational termination
DOM78_RS03580	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DOM78_RS03600	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DOM78_RS03605	COG1987	bacterial-type flagellum assembly
DOM78_RS03610	COG1047	Peptidyl-prolyl cis-trans
DOM78_RS03620	COG2885	chlorophyll binding
DOM78_RS03625	COG0823	Involved in the tonB-independent uptake of proteins
DOM78_RS03635	COG0848	biopolymer transport protein
DOM78_RS03640	COG0811	peptide transport
DOM78_RS03645	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DOM78_RS03650	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DOM78_RS03655	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DOM78_RS03660	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DOM78_RS03665	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DOM78_RS03670	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DOM78_RS03680	COG1475	DNA binding
DOM78_RS03685	COG1192	Involved in chromosome partitioning
DOM78_RS03695	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DOM78_RS03700	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DOM78_RS03705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DOM78_RS03715	COG1696	Membrane protein involved in D-alanine export
DOM78_RS03725	COG1696	Membrane protein involved in D-alanine export
DOM78_RS03730	COG0747	negative chemotaxis
DOM78_RS03735	COG0601	transmembrane transport
DOM78_RS03740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DOM78_RS03750	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
DOM78_RS03775	COG0463	Glycosyl transferase, family 2
DOM78_RS03785	COG0463	Glycosyl transferase, family 2
DOM78_RS03790	COG0840	transmembrane signaling receptor activity
DOM78_RS03825	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DOM78_RS03835	COG2346	COG2346, Truncated hemoglobins
DOM78_RS03840	COG2819	hydrolase of the alpha beta superfamily
DOM78_RS03860	COG3043	anaerobic respiration
DOM78_RS03865	COG0348	domain, Protein
DOM78_RS03870	COG0437	4 iron, 4 sulfur cluster binding
DOM78_RS03875	COG0243	molybdopterin cofactor binding
DOM78_RS03885	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DOM78_RS03890	COG0756	dUTP diphosphatase activity
DOM78_RS03905	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DOM78_RS03910	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DOM78_RS03940	COG0217	transcriptional regulatory protein
DOM78_RS03950	COG0113	porphobilinogen synthase activity
DOM78_RS03955	COG0642	Histidine kinase
DOM78_RS03960	COG0745	RESPONSE REGULATOR receiver
DOM78_RS03975	COG0037	tRNA processing
DOM78_RS03985	COG2814	Major facilitator Superfamily
DOM78_RS03990	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DOM78_RS04000	COG0793	Belongs to the peptidase S41A family
DOM78_RS04005	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DOM78_RS04010	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DOM78_RS04015	COG0047	phosphoribosylformylglycinamidine synthase activity
DOM78_RS04025	COG0204	Acyl-transferase
DOM78_RS04040	COG0124	histidyl-tRNA synthetase
DOM78_RS04065	COG3959	Transketolase, thiamine diphosphate binding domain
DOM78_RS04070	COG3959	Transketolase, thiamine diphosphate binding domain
DOM78_RS04075	COG3958	Transketolase
DOM78_RS04080	COG4221	oxidoreductase activity
DOM78_RS04090	COG4106	trans-aconitate 2-methyltransferase activity
DOM78_RS04120	COG1028	Short-chain dehydrogenase reductase Sdr
DOM78_RS04135	COG0859	PFAM glycosyl transferase family 9
DOM78_RS04140	COG0167	dihydroorotate dehydrogenase activity
DOM78_RS04145	COG0612	Peptidase, M16
DOM78_RS04150	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DOM78_RS04155	COG1028	Short-chain dehydrogenase reductase Sdr
DOM78_RS04160	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DOM78_RS04175	COG1115	amino acid carrier protein
DOM78_RS04185	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DOM78_RS04190	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
DOM78_RS04195	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DOM78_RS04200	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DOM78_RS04205	COG0811	peptide transport
DOM78_RS04210	COG0848	biopolymer transport protein
DOM78_RS04225	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DOM78_RS04230	COG0594	ribonuclease P activity
DOM78_RS04235	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DOM78_RS04240	COG0706	membrane insertase activity
DOM78_RS04250	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DOM78_RS04265	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DOM78_RS04270	COG1815	bacterial-type flagellum-dependent cell motility
DOM78_RS04275	COG1558	bacterial-type flagellum-dependent cell motility
DOM78_RS04280	COG1677	Flagellar hook-basal body complex protein FliE
DOM78_RS04300	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
DOM78_RS04340	COG1028	Short-chain dehydrogenase reductase Sdr
DOM78_RS04345	COG0534	Mate efflux family protein
DOM78_RS04355	COG0537	adenosine 5'-monophosphoramidase activity
DOM78_RS04360	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DOM78_RS04365	COG0072	phenylalanine-tRNA ligase activity
DOM78_RS04365	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DOM78_RS04370	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DOM78_RS04390	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DOM78_RS04395	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DOM78_RS04400	COG2207	Transcriptional regulator
DOM78_RS04400	COG4753	response regulator
DOM78_RS04415	COG0322	excinuclease ABC activity
DOM78_RS04430	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DOM78_RS04435	COG1322	Protein conserved in bacteria
DOM78_RS04440	COG0315	cyclic pyranopterin monophosphate synthase activity
DOM78_RS04445	COG0521	Mo-molybdopterin cofactor biosynthetic process
DOM78_RS04455	COG0314	molybdopterin synthase activity
DOM78_RS04465	COG0303	'Molybdopterin
DOM78_RS04470	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DOM78_RS04475	COG0586	Pfam SNARE associated Golgi protein
DOM78_RS04480	COG0288	reversible hydration of carbon dioxide
DOM78_RS04485	COG2877	3-deoxy-8-phosphooctulonate synthase activity
DOM78_RS04490	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DOM78_RS04495	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DOM78_RS04500	COG0284	orotidine-5'-phosphate decarboxylase activity
DOM78_RS04505	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DOM78_RS04540	COG0302	gtp cyclohydrolase
DOM78_RS04560	COG0745	RESPONSE REGULATOR receiver
DOM78_RS04565	COG0642	Histidine kinase
DOM78_RS04570	COG0305	Participates in initiation and elongation during chromosome replication
DOM78_RS04580	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
DOM78_RS04605	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DOM78_RS04610	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DOM78_RS04665	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DOM78_RS04670	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DOM78_RS04670	COG0551	DNA topoisomerase type I activity
DOM78_RS04675	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DOM78_RS04685	COG1739	Uncharacterized protein family UPF0029
DOM78_RS04690	COG1981	membrane
DOM78_RS04695	COG0165	Argininosuccinate lyase
DOM78_RS04705	COG0579	oxidoreductase
DOM78_RS04710	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DOM78_RS04730	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DOM78_RS04735	COG0442	prolyl-tRNA aminoacylation
DOM78_RS04740	COG0181	hydroxymethylbilane synthase activity
DOM78_RS04745	COG1295	ribonuclease BN
DOM78_RS04750	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DOM78_RS04755	COG1570	exodeoxyribonuclease VII activity
DOM78_RS04765	COG0709	Synthesizes selenophosphate from selenide and ATP
DOM78_RS04775	COG1049	propionate catabolic process, 2-methylcitrate cycle
DOM78_RS04785	COG1217	gtp-binding protein TYPA
DOM78_RS04790	COG0778	Nitroreductase
DOM78_RS04795	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DOM78_RS04810	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DOM78_RS04815	COG0268	Binds directly to 16S ribosomal RNA
DOM78_RS04820	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DOM78_RS04825	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DOM78_RS04850	COG2056	Na+-H+ antiporter family
DOM78_RS04860	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DOM78_RS04865	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DOM78_RS04870	COG1253	flavin adenine dinucleotide binding
DOM78_RS04875	COG0306	phosphate transporter
DOM78_RS04905	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DOM78_RS04915	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DOM78_RS04920	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DOM78_RS04930	COG0791	NLP P60 protein
DOM78_RS04940	COG0574	Belongs to the PEP-utilizing enzyme family
DOM78_RS04940	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DOM78_RS04945	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DOM78_RS04955	COG0352	thiamine-phosphate diphosphorylase activity
DOM78_RS04970	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
DOM78_RS04980	COG0731	radical SAM domain protein
DOM78_RS04985	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DOM78_RS04990	COG0157	Belongs to the NadC ModD family
DOM78_RS05000	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DOM78_RS05005	COG2885	chlorophyll binding
DOM78_RS05030	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DOM78_RS05035	COG2957	Belongs to the agmatine deiminase family
DOM78_RS05045	COG4974	Belongs to the 'phage' integrase family
DOM78_RS05070	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DOM78_RS05075	COG0439	Biotin carboxylase
DOM78_RS05080	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DOM78_RS05080	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DOM78_RS05085	COG2022	thiamine diphosphate biosynthetic process
DOM78_RS05090	COG2226	methyltransferase
DOM78_RS05115	COG1696	Membrane protein involved in D-alanine export
DOM78_RS05125	COG0577	efflux transmembrane transporter activity
DOM78_RS05125	COG1136	(ABC) transporter
DOM78_RS05130	COG0577	efflux transmembrane transporter activity
DOM78_RS05130	COG1136	(ABC) transporter
DOM78_RS05135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DOM78_RS05200	COG0124	histidyl-tRNA synthetase
DOM78_RS05210	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DOM78_RS05215	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DOM78_RS05225	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DOM78_RS05230	COG0784	Response regulator, receiver
DOM78_RS05230	COG0835	chemotaxis
DOM78_RS05235	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DOM78_RS05245	COG0563	adenylate kinase activity
DOM78_RS05265	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DOM78_RS05275	COG0513	Belongs to the DEAD box helicase family
DOM78_RS05280	COG0785	Cytochrome C biogenesis protein
DOM78_RS05285	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DOM78_RS05290	COG0668	transmembrane transport
DOM78_RS05295	COG0402	S-adenosylhomocysteine deaminase activity
DOM78_RS05300	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DOM78_RS05320	COG1121	(ABC) transporter
DOM78_RS05325	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DOM78_RS05335	COG0792	nuclease activity
DOM78_RS05340	COG0460	homoserine dehydrogenase
DOM78_RS05345	COG0436	Aminotransferase
DOM78_RS05360	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DOM78_RS05365	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DOM78_RS05370	COG0254	rRNA binding
DOM78_RS05395	COG0326	Molecular chaperone. Has ATPase activity
DOM78_RS05400	COG0840	transmembrane signaling receptor activity
DOM78_RS05405	COG0840	transmembrane signaling receptor activity
DOM78_RS05425	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DOM78_RS05430	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DOM78_RS05435	COG0163	prenyltransferase activity
DOM78_RS05460	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DOM78_RS05480	COG0765	amino acid transport
DOM78_RS05485	COG0765	amino acid transport
DOM78_RS05490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DOM78_RS05495	COG1126	abc transporter atp-binding protein
DOM78_RS05525	COG0133	tryptophan synthase activity
DOM78_RS05530	COG0159	tryptophan synthase activity
DOM78_RS05545	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DOM78_RS05555	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DOM78_RS05555	COG0519	Catalyzes the synthesis of GMP from XMP
DOM78_RS05580	COG0617	tRNA 3'-terminal CCA addition
DOM78_RS05585	COG0644	oxidoreductase
DOM78_RS05590	COG1454	alcohol dehydrogenase
DOM78_RS05595	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
DOM78_RS05595	COG0028	Belongs to the TPP enzyme family
DOM78_RS05620	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DOM78_RS05630	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DOM78_RS05635	COG0574	Belongs to the PEP-utilizing enzyme family
DOM78_RS05635	COG3848	Pyruvate phosphate dikinase
DOM78_RS05640	COG0500	methyltransferase
DOM78_RS05645	COG0706	membrane insertase activity
DOM78_RS05665	COG1749	Flagellar hook protein flgE
DOM78_RS05675	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DOM78_RS05690	COG0237	dephospho-CoA kinase activity
DOM78_RS05695	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DOM78_RS05715	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DOM78_RS05730	COG0788	formyltetrahydrofolate deformylase activity
DOM78_RS05735	COG0616	signal peptide processing
DOM78_RS05740	COG0251	oxidation-reduction process
DOM78_RS05755	COG5016	pyruvate
DOM78_RS05755	COG0511	ligase activity, forming carbon-carbon bonds
DOM78_RS05760	COG3022	response to hydroperoxide
DOM78_RS05775	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DOM78_RS05780	COG0750	zinc metalloprotease
DOM78_RS05785	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DOM78_RS05790	COG0598	Magnesium transport protein CorA
DOM78_RS05795	COG0861	Integral membrane protein TerC family
DOM78_RS05840	COG4172	Belongs to the ABC transporter superfamily
DOM78_RS05845	COG4239	(ABC) transporter, permease
DOM78_RS05850	COG4174	ABC transporter (Permease)
DOM78_RS05855	COG2879	small protein
DOM78_RS05870	COG1966	Carbon starvation protein
DOM78_RS05880	COG0134	indole-3-glycerol-phosphate synthase activity
DOM78_RS05885	COG2843	Capsule synthesis protein
DOM78_RS05895	COG2703	oxygen carrier activity
DOM78_RS05900	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DOM78_RS05905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DOM78_RS05910	COG0765	amino acid transport
DOM78_RS05925	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DOM78_RS05930	COG1216	Glycosyl transferase, family 2
DOM78_RS05930	COG1442	glycosyl transferase family 8
DOM78_RS05940	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DOM78_RS05945	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DOM78_RS05955	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DOM78_RS05965	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DOM78_RS05995	COG1028	Short-chain dehydrogenase reductase Sdr
DOM78_RS06025	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DOM78_RS06040	COG1028	Short-chain dehydrogenase reductase Sdr
DOM78_RS06060	COG2089	acid synthase
DOM78_RS06070	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DOM78_RS06085	COG1028	Short-chain dehydrogenase reductase Sdr
DOM78_RS06115	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DOM78_RS06125	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DOM78_RS06135	COG0445	tRNA wobble uridine modification
DOM78_RS06145	COG0754	glutathionylspermidine amidase activity
DOM78_RS06150	COG2194	sulfuric ester hydrolase activity
DOM78_RS06155	COG3118	belongs to the thioredoxin family
DOM78_RS06160	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
DOM78_RS06165	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
DOM78_RS06170	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
DOM78_RS06175	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
DOM78_RS06190	COG0626	cystathionine gamma-synthase activity
DOM78_RS06210	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DOM78_RS06295	COG0481	GTPase activity
DOM78_RS06305	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DOM78_RS06320	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DOM78_RS06325	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DOM78_RS06330	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DOM78_RS06360	COG1083	cytidylyl-transferase
DOM78_RS06365	COG4221	oxidoreductase activity
DOM78_RS06420	COG0772	Belongs to the SEDS family
DOM78_RS06435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DOM78_RS06440	COG0191	fructose-bisphosphate aldolase activity
DOM78_RS06445	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DOM78_RS06470	COG0542	response to heat
DOM78_RS06490	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DOM78_RS06500	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DOM78_RS06510	COG0698	ribose 5-phosphate isomerase
DOM78_RS06515	COG0681	Belongs to the peptidase S26 family
DOM78_RS06520	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DOM78_RS06530	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DOM78_RS06535	COG1607	acyl-coa hydrolase
DOM78_RS06555	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DOM78_RS06560	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DOM78_RS06565	COG1862	Preprotein translocase
DOM78_RS06570	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DOM78_RS06575	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DOM78_RS06590	COG0789	Transcriptional regulator
DOM78_RS06595	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DOM78_RS06610	COG2204	response regulator
DOM78_RS06620	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DOM78_RS06640	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DOM78_RS06645	COG1254	Belongs to the acylphosphatase family
DOM78_RS06655	COG1181	Belongs to the D-alanine--D-alanine ligase family
DOM78_RS06660	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DOM78_RS06675	COG1185	polyribonucleotide nucleotidyltransferase activity
DOM78_RS06675	COG0539	negative regulation of cytoplasmic translation
DOM78_RS06680	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DOM78_RS06685	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DOM78_RS06690	COG1760	l-serine dehydratase
DOM78_RS06695	COG0642	Histidine kinase
DOM78_RS06700	COG3951	Flagellar rod assembly protein muramidase FlgJ
DOM78_RS06705	COG1706	bacterial-type flagellum-dependent cell motility
DOM78_RS06785	COG4735	regulation of single-species biofilm formation
DOM78_RS06825	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DOM78_RS06835	COG0739	heme binding
DOM78_RS06860	COG0495	leucyl-tRNA aminoacylation
DOM78_RS06935	COG0582	viral genome integration into host DNA
DOM78_RS07015	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DOM78_RS07025	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
DOM78_RS07280	COG2189	Belongs to the N(4) N(6)-methyltransferase family
DOM78_RS07935	COG3177	Filamentation induced by cAMP protein fic
DOM78_RS08150	COG2095	MarC family integral membrane protein
DOM78_RS08155	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DOM78_RS08160	COG2404	hydrolase activity, acting on ester bonds
DOM78_RS08170	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DOM78_RS08175	COG0569	domain protein
DOM78_RS08175	COG0475	glutathione-regulated potassium exporter activity
DOM78_RS08180	COG0733	neurotransmitter:sodium symporter activity
DOM78_RS08185	COG4166	transmembrane transport
DOM78_RS08190	COG1132	(ABC) transporter
DOM78_RS08195	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DOM78_RS08205	COG0138	bifunctional purine biosynthesis protein purh
DOM78_RS08220	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DOM78_RS08225	COG0492	ferredoxin-NADP+ reductase activity
DOM78_RS08230	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DOM78_RS08235	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DOM78_RS08240	COG1242	4 iron, 4 sulfur cluster binding
DOM78_RS08245	COG0166	Belongs to the GPI family
DOM78_RS08260	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DOM78_RS08270	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
DOM78_RS08275	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DOM78_RS08280	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DOM78_RS08290	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DOM78_RS08295	COG1360	Flagellar Motor Protein
DOM78_RS08310	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DOM78_RS08315	COG0049	tRNA binding
DOM78_RS08320	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DOM78_RS08325	COG0085	RNA polymerase activity
DOM78_RS08325	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DOM78_RS08330	COG0222	ribosome binding
DOM78_RS08335	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DOM78_RS08340	COG0081	regulation of translation
DOM78_RS08345	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DOM78_RS08350	COG0250	Participates in transcription elongation, termination and antitermination
DOM78_RS08365	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DOM78_RS08370	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DOM78_RS08425	COG0436	Aminotransferase
DOM78_RS08440	COG1193	negative regulation of DNA recombination
DOM78_RS08455	COG0840	transmembrane signaling receptor activity
DOM78_RS08460	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DOM78_RS08470	COG0439	Biotin carboxylase
DOM78_RS08475	COG0511	ligase activity, forming carbon-carbon bonds
DOM78_RS08480	COG0717	Belongs to the dCTP deaminase family
DOM78_RS08500	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
DOM78_RS08505	COG1749	Flagellar hook protein flgE
DOM78_RS08525	COG1598	PFAM Uncharacterised protein family UPF0150
DOM78_RS08600	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
DOM78_RS08610	COG2079	MmgE PrpD family protein
DOM78_RS08615	COG0372	Belongs to the citrate synthase family
DOM78_RS08635	COG1741	Belongs to the pirin family
DOM78_RS08645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DOM78_RS08650	COG1854	S-ribosylhomocysteine lyase activity
DOM78_RS08660	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DOM78_RS08665	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DOM78_RS08675	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
DOM78_RS08680	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DOM78_RS08690	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DOM78_RS08690	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DOM78_RS08695	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DOM78_RS08725	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DOM78_RS08730	COG1918	ferrous iron import across plasma membrane
DOM78_RS08760	COG0674	pyruvate-flavodoxin oxidoreductase activity
DOM78_RS08760	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DOM78_RS08765	COG1013	pyruvate-flavodoxin oxidoreductase activity
DOM78_RS08775	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DOM78_RS08780	COG0542	response to heat
DOM78_RS08800	COG4221	oxidoreductase activity
DOM78_RS08805	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
DOM78_RS08815	COG2255	four-way junction helicase activity
DOM78_RS08820	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DOM78_RS08825	COG2076	Multidrug Resistance protein
DOM78_RS08835	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DOM78_RS08855	COG0632	four-way junction helicase activity
DOM78_RS08865	COG0728	peptidoglycan biosynthetic process
DOM78_RS08870	COG0215	cysteine-tRNA ligase activity
DOM78_RS08875	COG0196	riboflavin kinase activity
DOM78_RS08890	COG0540	Belongs to the ATCase OTCase family
DOM78_RS08900	COG0575	Belongs to the CDS family
DOM78_RS08905	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DOM78_RS08910	COG1473	amidohydrolase
DOM78_RS09095	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DOM78_RS09100	COG1921	L-seryl-tRNASec selenium transferase activity
DOM78_RS09115	COG0303	'Molybdopterin
DOM78_RS09120	COG0589	response to stress
DOM78_RS09150	COG2194	sulfuric ester hydrolase activity
DOM78_RS09155	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DOM78_RS09175	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DOM78_RS09180	COG0849	cell division
DOM78_RS09195	COG0772	Belongs to the SEDS family
DOM78_RS09200	COG0564	pseudouridine synthase activity
DOM78_RS09210	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DOM78_RS09215	COG1136	(ABC) transporter
DOM78_RS09235	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
DOM78_RS09250	COG0776	regulation of translation
DOM78_RS09255	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DOM78_RS09265	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DOM78_RS09310	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DOM78_RS09315	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DOM78_RS09320	COG0375	protein maturation
DOM78_RS09335	COG1215	transferase activity, transferring glycosyl groups
DOM78_RS09370	COG0733	neurotransmitter:sodium symporter activity
DOM78_RS09395	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DOM78_RS09415	COG0477	Major facilitator Superfamily
DOM78_RS09420	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DOM78_RS09425	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
DOM78_RS09435	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DOM78_RS09480	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DOM78_RS09485	COG0671	phosphoesterase, PA-phosphatase related
DOM78_RS09490	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DOM78_RS09495	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DOM78_RS09500	COG0440	acetolactate synthase activity
DOM78_RS09505	COG0028	Belongs to the TPP enzyme family
DOM78_RS09510	COG2807	transmembrane transport
DOM78_RS09535	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DOM78_RS09545	COG0277	FAD linked oxidase domain protein
DOM78_RS09560	COG1196	nuclear chromosome segregation
DOM78_RS09560	COG0739	heme binding
DOM78_RS09560	COG0741	lytic transglycosylase activity
DOM78_RS09595	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DOM78_RS09600	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DOM78_RS09610	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DOM78_RS09630	COG0824	Thioesterase
DOM78_RS09690	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DOM78_RS09700	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DOM78_RS09710	COG0733	neurotransmitter:sodium symporter activity
DOM78_RS09715	COG0505	Belongs to the CarA family
DOM78_RS09725	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DOM78_RS09735	COG0735	belongs to the Fur family
DOM78_RS09755	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DOM78_RS09760	COG0697	spore germination
DOM78_RS09765	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
DOM78_RS09770	COG1083	cytidylyl-transferase
DOM78_RS09785	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DOM78_RS09790	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DOM78_RS09795	COG2089	acid synthase
DOM78_RS09800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DOM78_RS09805	COG0352	thiamine-phosphate diphosphorylase activity
DOM78_RS09810	COG0670	Belongs to the BI1 family
DOM78_RS09815	COG0348	domain, Protein
DOM78_RS09825	COG0488	(ABC) transporter
DOM78_RS09850	COG2195	Cleaves the N-terminal amino acid of tripeptides
DOM78_RS09855	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DOM78_RS09865	COG0784	Response regulator, receiver
DOM78_RS09865	COG0835	chemotaxis
DOM78_RS09870	COG2198	Histidine kinase
DOM78_RS09870	COG0784	Response regulator, receiver
DOM78_RS09870	COG0643	Histidine kinase
DOM78_RS09875	COG0835	chemotaxis
DOM78_RS09895	COG0560	Phosphoserine phosphatase
DOM78_RS09900	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
DOM78_RS09900	COG0662	Cupin 2, conserved barrel domain protein
DOM78_RS09905	COG1793	dna ligase
DOM78_RS09910	COG0105	UTP biosynthetic process
DOM78_RS09920	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DOM78_RS09925	COG0416	fatty acid biosynthetic process
DOM78_RS09930	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DOM78_RS09935	COG2217	Heavy metal translocating P-type atpase
DOM78_RS09940	COG2608	mercury ion transmembrane transporter activity
DOM78_RS09950	COG0343	queuine tRNA-ribosyltransferase activity
DOM78_RS09965	COG2217	Heavy metal translocating P-type atpase
DOM78_RS09970	COG2608	mercury ion transmembrane transporter activity
DOM78_RS09975	COG1132	(ABC) transporter
DOM78_RS09985	COG1053	succinate dehydrogenase
DOM78_RS09990	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DOM78_RS09995	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DOM78_RS10010	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DOM78_RS10020	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DOM78_RS10025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DOM78_RS10055	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DOM78_RS10060	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DOM78_RS10080	COG0275	rRNA processing
DOM78_RS10105	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DOM78_RS10115	COG0243	molybdopterin cofactor binding
DOM78_RS10135	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DOM78_RS10140	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
DOM78_RS10145	COG0482	sulfurtransferase activity
DOM78_RS10150	COG4771	TonB-dependent receptor
DOM78_RS10155	COG1027	Aspartate ammonia-lyase
DOM78_RS10160	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
DOM78_RS10185	COG0194	GDP metabolic process
DOM78_RS10195	COG0018	arginyl-trna synthetase
DOM78_RS10200	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DOM78_RS10205	COG1687	branched-chain amino acid
DOM78_RS10210	COG0716	FMN binding
DOM78_RS10215	COG4771	TonB-dependent receptor
DOM78_RS10245	COG2011	ABC-type metal ion transport system permease component
DOM78_RS10250	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DOM78_RS10255	COG1187	pseudouridine synthase activity
DOM78_RS10270	COG2171	N-acyltransferase activity
DOM78_RS10285	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DOM78_RS10305	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DOM78_RS10315	COG0840	transmembrane signaling receptor activity
DOM78_RS10320	COG1293	RNA-binding protein homologous to eukaryotic snRNP
DOM78_RS10325	COG0497	DNA recombination
DOM78_RS10330	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DOM78_RS10360	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DOM78_RS10365	COG0280	phosphate acetyltransferase
DOM78_RS10370	COG0840	transmembrane signaling receptor activity
DOM78_RS10375	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DOM78_RS10380	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DOM78_RS10385	COG0149	triose-phosphate isomerase activity
DOM78_RS10395	COG2189	Belongs to the N(4) N(6)-methyltransferase family
DOM78_RS10400	COG3421	Type III restriction
DOM78_RS10585	COG0629	single-stranded DNA binding
DOM78_RS10590	COG0582	viral genome integration into host DNA
DOM78_RS10620	COG2249	NAD(P)H dehydrogenase (quinone) activity
DOM78_RS10625	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DOM78_RS10635	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DOM78_RS10645	COG0084	hydrolase, TatD family'
DOM78_RS10650	COG0741	lytic transglycosylase activity
DOM78_RS10650	COG0739	heme binding
DOM78_RS10650	COG1196	nuclear chromosome segregation
DOM78_RS10655	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DOM78_RS10660	COG0131	Imidazoleglycerol-phosphate dehydratase
DOM78_RS10665	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DOM78_RS10680	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DOM78_RS10695	COG0768	penicillin binding
DOM78_RS10700	COG1086	Polysaccharide biosynthesis protein
DOM78_RS10705	COG1528	Iron-storage protein
DOM78_RS10710	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DOM78_RS10725	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DOM78_RS10725	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DOM78_RS10780	COG0037	tRNA processing
DOM78_RS10790	COG2851	Citrate transporter
DOM78_RS10795	COG0748	coenzyme F420 binding
DOM78_RS10805	COG1408	metallophosphoesterase
DOM78_RS10815	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DOM78_RS10820	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DOM78_RS10825	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DOM78_RS10850	COG1194	a g-specific adenine glycosylase
DOM78_RS10860	COG0004	ammonium transporteR
DOM78_RS10865	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DOM78_RS10880	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DOM78_RS10885	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DOM78_RS10900	COG1045	serine acetyltransferase
DOM78_RS10905	COG1166	arginine decarboxylase activity
DOM78_RS10910	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DOM78_RS10920	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DOM78_RS10935	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
DOM78_RS10940	COG2894	cell division
DOM78_RS10955	COG0137	argininosuccinate synthase activity
DOM78_RS10960	COG2076	Multidrug Resistance protein
DOM78_RS11045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DOM78_RS11055	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DOM78_RS11060	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DOM78_RS11075	COG0459	protein refolding
DOM78_RS11080	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DOM78_RS11085	COG0482	sulfurtransferase activity
DOM78_RS11090	COG0358	DNA primase activity
DOM78_RS11110	COG2824	Alkylphosphonate utilization operon protein PhnA
DOM78_RS11125	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DOM78_RS11130	COG0179	Fumarylacetoacetate (FAA) hydrolase
DOM78_RS11150	COG1077	Cell shape determining protein MreB Mrl
DOM78_RS11155	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DOM78_RS11165	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DOM78_RS11170	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DOM78_RS11175	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DOM78_RS11185	COG0107	imidazoleglycerol-phosphate synthase activity
DOM78_RS11190	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DOM78_RS11195	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DOM78_RS11200	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DOM78_RS11200	COG0517	IMP dehydrogenase activity
DOM78_RS11210	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DOM78_RS11235	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DOM78_RS11245	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DOM78_RS11250	COG0066	3-isopropylmalate dehydratase activity
DOM78_RS11265	COG0473	3-isopropylmalate dehydrogenase activity
DOM78_RS11295	COG0187	DNA topoisomerase II activity
DOM78_RS11300	COG0592	DNA-directed DNA polymerase activity
DOM78_RS11305	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DOM78_RS11310	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DOM78_RS11340	COG1459	type II secretion system
DOM78_RS11345	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DOM78_RS11370	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group