locus-tag	class	description
CNX73_RS00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CNX73_RS00025	COG0708	Exodeoxyribonuclease III
CNX73_RS00040	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CNX73_RS00070	COG0195	Participates in both transcription termination and antitermination
CNX73_RS00095	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CNX73_RS00100	COG0348	domain, Protein
CNX73_RS00110	COG0786	glutamate:sodium symporter activity
CNX73_RS00120	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CNX73_RS00125	COG2217	Heavy metal translocating P-type atpase
CNX73_RS00170	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CNX73_RS00175	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CNX73_RS00185	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CNX73_RS00190	COG0306	phosphate transporter
CNX73_RS00195	COG1253	flavin adenine dinucleotide binding
CNX73_RS00205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CNX73_RS00220	COG1739	Uncharacterized protein family UPF0029
CNX73_RS00225	COG1981	membrane
CNX73_RS00230	COG2226	methyltransferase
CNX73_RS00265	COG0163	prenyltransferase activity
CNX73_RS00270	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CNX73_RS00300	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CNX73_RS00300	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CNX73_RS00310	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CNX73_RS00320	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CNX73_RS00325	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CNX73_RS00350	COG0587	DNA-directed DNA polymerase activity
CNX73_RS00355	COG1187	pseudouridine synthase activity
CNX73_RS00360	COG3118	belongs to the thioredoxin family
CNX73_RS00395	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CNX73_RS00405	COG0706	membrane insertase activity
CNX73_RS00425	COG0848	biopolymer transport protein
CNX73_RS00430	COG0811	peptide transport
CNX73_RS00440	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CNX73_RS00445	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CNX73_RS00450	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CNX73_RS00490	COG0616	signal peptide processing
CNX73_RS00495	COG0788	formyltetrahydrofolate deformylase activity
CNX73_RS00500	COG0732	type I restriction modification DNA specificity domain
CNX73_RS00520	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CNX73_RS00520	COG0517	IMP dehydrogenase activity
CNX73_RS00545	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CNX73_RS00555	COG4962	Type ii secretion system protein e
CNX73_RS00560	COG1157	protein secretion by the type III secretion system
CNX73_RS00565	COG1987	bacterial-type flagellum assembly
CNX73_RS00570	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CNX73_RS00590	COG0793	Belongs to the peptidase S41A family
CNX73_RS00600	COG0204	Acyl-transferase
CNX73_RS00610	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CNX73_RS00615	COG0126	phosphoglycerate kinase activity
CNX73_RS00620	COG0598	Magnesium transport protein CorA
CNX73_RS00625	COG0861	Integral membrane protein TerC family
CNX73_RS00635	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CNX73_RS00640	COG0848	biopolymer transport protein
CNX73_RS00645	COG0811	peptide transport
CNX73_RS00675	COG0484	heat shock protein binding
CNX73_RS00680	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CNX73_RS00685	COG1687	branched-chain amino acid
CNX73_RS00690	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CNX73_RS00695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CNX73_RS00710	COG0114	fumarate hydratase activity
CNX73_RS00740	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CNX73_RS00780	COG0255	Belongs to the universal ribosomal protein uL29 family
CNX73_RS00825	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CNX73_RS00835	COG0201	protein transport
CNX73_RS00840	COG0024	Methionine aminopeptidase
CNX73_RS00845	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CNX73_RS00865	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CNX73_RS00870	COG0202	RNA polymerase activity
CNX73_RS00905	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CNX73_RS00910	COG2353	YceI-like domain
CNX73_RS00920	COG0859	PFAM glycosyl transferase family 9
CNX73_RS00925	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CNX73_RS00930	COG0512	Glutamine amidotransferase of anthranilate synthase
CNX73_RS00935	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CNX73_RS00940	COG0134	indole-3-glycerol-phosphate synthase activity
CNX73_RS00940	COG0135	phosphoribosylanthranilate isomerase activity
CNX73_RS00945	COG0133	tryptophan synthase activity
CNX73_RS00970	COG1007	ATP synthesis coupled electron transport
CNX73_RS00980	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CNX73_RS00990	COG0839	Belongs to the complex I subunit 6 family
CNX73_RS00995	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CNX73_RS01000	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CNX73_RS01035	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CNX73_RS01040	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CNX73_RS01055	COG0233	cytoplasmic translational termination
CNX73_RS01060	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CNX73_RS01070	COG0180	Tryptophanyl-tRNA synthetase
CNX73_RS01075	COG4166	transmembrane transport
CNX73_RS01080	COG4174	ABC transporter (Permease)
CNX73_RS01095	COG0557	exoribonuclease II activity
CNX73_RS01100	COG1466	dna polymerase III delta subunit
CNX73_RS01115	COG0629	single-stranded DNA binding
CNX73_RS01135	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CNX73_RS01155	COG0505	Belongs to the CarA family
CNX73_RS01170	COG0697	spore germination
CNX73_RS01180	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CNX73_RS01195	COG0527	aspartate kinase activity
CNX73_RS01205	COG2863	cytochrome
CNX73_RS01210	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CNX73_RS01235	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CNX73_RS01240	COG1131	(ABC) transporter
CNX73_RS01260	COG0151	Belongs to the GarS family
CNX73_RS01270	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CNX73_RS01300	COG1045	serine acetyltransferase
CNX73_RS01325	COG1132	(ABC) transporter
CNX73_RS01350	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CNX73_RS01370	COG0250	Participates in transcription elongation, termination and antitermination
CNX73_RS01400	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CNX73_RS01400	COG0085	RNA polymerase activity
CNX73_RS01420	COG0667	Aldo Keto reductase
CNX73_RS01430	COG0859	PFAM glycosyl transferase family 9
CNX73_RS01435	COG0124	histidyl-tRNA synthetase
CNX73_RS01440	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CNX73_RS01455	COG2814	Major facilitator Superfamily
CNX73_RS01465	COG0569	domain protein
CNX73_RS01465	COG0475	glutathione-regulated potassium exporter activity
CNX73_RS01470	COG0037	tRNA processing
CNX73_RS01475	COG2814	Major facilitator Superfamily
CNX73_RS01485	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CNX73_RS01495	COG0813	purine-nucleoside phosphorylase activity
CNX73_RS01515	COG2252	PERMEase
CNX73_RS01520	COG0738	Major facilitator superfamily
CNX73_RS01535	COG1126	abc transporter atp-binding protein
CNX73_RS01540	COG0765	amino acid transport
CNX73_RS01550	COG1966	Carbon starvation protein
CNX73_RS01560	COG0166	Belongs to the GPI family
CNX73_RS01570	COG0492	ferredoxin-NADP+ reductase activity
CNX73_RS01585	COG0716	FMN binding
CNX73_RS01600	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CNX73_RS01615	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CNX73_RS01625	COG0525	valine-tRNA ligase activity
CNX73_RS01630	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CNX73_RS01635	COG0228	four-way junction DNA binding
CNX73_RS01645	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CNX73_RS01650	COG0336	Belongs to the RNA methyltransferase TrmD family
CNX73_RS01655	COG0335	large ribosomal subunit rRNA binding
CNX73_RS01710	COG1192	Involved in chromosome partitioning
CNX73_RS01715	COG1475	DNA binding
CNX73_RS01740	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CNX73_RS01750	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CNX73_RS01755	COG0811	peptide transport
CNX73_RS01760	COG0848	biopolymer transport protein
CNX73_RS01770	COG0823	Involved in the tonB-independent uptake of proteins
CNX73_RS01775	COG2885	chlorophyll binding
CNX73_RS01785	COG1047	Peptidyl-prolyl cis-trans
CNX73_RS01815	COG0405	Gamma-glutamyltransferase
CNX73_RS01855	COG0556	nucleotide-excision repair
CNX73_RS01865	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CNX73_RS01870	COG1013	pyruvate-flavodoxin oxidoreductase activity
CNX73_RS01875	COG0674	pyruvate-flavodoxin oxidoreductase activity
CNX73_RS01885	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CNX73_RS01905	COG1064	alcohol dehydrogenase
CNX73_RS01915	COG0363	glucosamine-6-phosphate deaminase activity
CNX73_RS01920	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CNX73_RS01925	COG0129	dihydroxy-acid dehydratase activity
CNX73_RS01930	COG0800	Aldolase
CNX73_RS01935	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CNX73_RS01940	COG4221	oxidoreductase activity
CNX73_RS01980	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CNX73_RS01990	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CNX73_RS02010	COG0439	Biotin carboxylase
CNX73_RS02015	COG0511	ligase activity, forming carbon-carbon bonds
CNX73_RS02030	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CNX73_RS02040	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CNX73_RS02050	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CNX73_RS02050	COG1333	cytochrome c biogenesis protein
CNX73_RS02060	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CNX73_RS02065	COG2890	protein-(glutamine-N5) methyltransferase activity
CNX73_RS02070	COG0501	Belongs to the peptidase M48B family
CNX73_RS02095	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CNX73_RS02100	COG2226	methyltransferase
CNX73_RS02105	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CNX73_RS02110	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CNX73_RS02115	COG0835	chemotaxis
CNX73_RS02120	COG0784	Response regulator, receiver
CNX73_RS02120	COG0643	Histidine kinase
CNX73_RS02120	COG2198	Histidine kinase
CNX73_RS02135	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CNX73_RS02140	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CNX73_RS02145	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CNX73_RS02155	COG1185	polyribonucleotide nucleotidyltransferase activity
CNX73_RS02155	COG0539	negative regulation of cytoplasmic translation
CNX73_RS02165	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CNX73_RS02170	COG0072	phenylalanine-tRNA ligase activity
CNX73_RS02170	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CNX73_RS02180	COG0537	adenosine 5'-monophosphoramidase activity
CNX73_RS02185	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CNX73_RS02240	COG0668	transmembrane transport
CNX73_RS02245	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CNX73_RS02250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CNX73_RS02250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CNX73_RS02275	COG1166	arginine decarboxylase activity
CNX73_RS02285	COG1598	PFAM Uncharacterised protein family UPF0150
CNX73_RS02350	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CNX73_RS02350	COG0551	DNA topoisomerase type I activity
CNX73_RS02390	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
CNX73_RS02425	COG1192	Involved in chromosome partitioning
CNX73_RS02485	COG0675	Transposase, IS605 OrfB family
CNX73_RS02505	COG4974	Belongs to the 'phage' integrase family
CNX73_RS02510	COG3550	peptidyl-serine autophosphorylation
CNX73_RS02560	COG1192	Involved in chromosome partitioning
CNX73_RS02585	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CNX73_RS02600	COG4962	Type ii secretion system protein e
CNX73_RS02640	COG3451	type IV secretory pathway VirB4
CNX73_RS02700	COG0668	transmembrane transport
CNX73_RS02725	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CNX73_RS02730	COG0849	cell division
CNX73_RS02740	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CNX73_RS02760	COG0751	glycine-tRNA ligase activity
CNX73_RS02785	COG3309	Virulence-associated protein D
CNX73_RS02795	COG1160	GTP binding
CNX73_RS02815	COG0752	glycyl-tRNA synthetase alpha subunit
CNX73_RS02820	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CNX73_RS02830	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CNX73_RS02830	COG1519	Transferase
CNX73_RS02835	COG0564	pseudouridine synthase activity
CNX73_RS02855	COG1546	Belongs to the CinA family
CNX73_RS02855	COG1058	Belongs to the CinA family
CNX73_RS02865	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CNX73_RS02890	COG1757	Na H antiporter
CNX73_RS02915	COG0251	oxidation-reduction process
CNX73_RS02920	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CNX73_RS02925	COG1115	amino acid carrier protein
CNX73_RS02935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CNX73_RS02940	COG0765	amino acid transport
CNX73_RS02970	COG0602	queuosine metabolic process
CNX73_RS02975	COG0720	synthase
CNX73_RS02985	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CNX73_RS02990	COG0142	geranyltranstransferase activity
CNX73_RS03000	COG0501	Belongs to the peptidase M48B family
CNX73_RS03015	COG1942	4-Oxalocrotonate Tautomerase
CNX73_RS03030	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CNX73_RS03035	COG0670	Belongs to the BI1 family
CNX73_RS03040	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CNX73_RS03090	COG1749	Flagellar hook protein flgE
CNX73_RS03090	COG1749	Flagellar hook protein flgE
CNX73_RS03095	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CNX73_RS03105	COG0280	phosphate acetyltransferase
CNX73_RS03125	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CNX73_RS03130	COG0298	carbon dioxide binding
CNX73_RS03135	COG0409	Hydrogenase expression formation protein
CNX73_RS03170	COG3041	Addiction module toxin RelE StbE family
CNX73_RS03175	COG1607	acyl-coa hydrolase
CNX73_RS03180	COG0300	oxidoreductase activity
CNX73_RS03185	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CNX73_RS03190	COG1120	ATPase activity
CNX73_RS03200	COG0215	cysteine-tRNA ligase activity
CNX73_RS03205	COG0728	peptidoglycan biosynthetic process
CNX73_RS03215	COG0632	four-way junction helicase activity
CNX73_RS03265	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CNX73_RS03280	COG0824	Thioesterase
CNX73_RS03285	COG0733	neurotransmitter:sodium symporter activity
CNX73_RS03290	COG0733	neurotransmitter:sodium symporter activity
CNX73_RS03300	COG0592	DNA-directed DNA polymerase activity
CNX73_RS03305	COG0187	DNA topoisomerase II activity
CNX73_RS03320	COG0739	heme binding
CNX73_RS03320	COG0741	lytic transglycosylase activity
CNX73_RS03320	COG1196	nuclear chromosome segregation
CNX73_RS03335	COG0277	FAD linked oxidase domain protein
CNX73_RS03340	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CNX73_RS03360	COG3451	type IV secretory pathway VirB4
CNX73_RS03500	COG0174	glutamine synthetase
CNX73_RS03505	COG3586	endonuclease activity
CNX73_RS03510	COG0359	binds to the 23S rRNA
CNX73_RS03570	COG1842	Phage shock protein A
CNX73_RS03585	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CNX73_RS03595	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CNX73_RS03625	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CNX73_RS03635	COG1028	Short-chain dehydrogenase reductase Sdr
CNX73_RS03660	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CNX73_RS03665	COG0628	permease
CNX73_RS03675	COG0012	GTP binding
CNX73_RS03680	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CNX73_RS03700	COG0698	ribose 5-phosphate isomerase
CNX73_RS03705	COG1994	Peptidase M50
CNX73_RS03710	COG0681	Belongs to the peptidase S26 family
CNX73_RS03715	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CNX73_RS03735	COG0418	dihydroorotase activity
CNX73_RS03750	COG1776	CheC inhibitor of MCP methylation
CNX73_RS03750	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CNX73_RS03755	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CNX73_RS03760	COG1918	ferrous iron import across plasma membrane
CNX73_RS03780	COG0674	pyruvate-flavodoxin oxidoreductase activity
CNX73_RS03780	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CNX73_RS03785	COG1013	pyruvate-flavodoxin oxidoreductase activity
CNX73_RS03820	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CNX73_RS03825	COG0156	8-amino-7-oxononanoate synthase activity
CNX73_RS03830	COG0840	transmembrane signaling receptor activity
CNX73_RS03845	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CNX73_RS03895	COG1131	(ABC) transporter
CNX73_RS03905	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CNX73_RS03910	COG0835	chemotaxis
CNX73_RS03910	COG0784	Response regulator, receiver
CNX73_RS03920	COG0563	adenylate kinase activity
CNX73_RS03925	COG3306	glycosyltransferase involved in LPS biosynthesis
CNX73_RS03935	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CNX73_RS03940	COG1193	negative regulation of DNA recombination
CNX73_RS03955	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CNX73_RS03965	COG2171	N-acyltransferase activity
CNX73_RS03980	COG2249	NAD(P)H dehydrogenase (quinone) activity
CNX73_RS03985	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CNX73_RS03990	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CNX73_RS03995	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
CNX73_RS04000	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CNX73_RS04005	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CNX73_RS04030	COG0617	tRNA 3'-terminal CCA addition
CNX73_RS04045	COG0778	Nitroreductase
CNX73_RS04080	COG1027	Aspartate ammonia-lyase
CNX73_RS04095	COG0560	Phosphoserine phosphatase
CNX73_RS04100	COG1528	Iron-storage protein
CNX73_RS04105	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CNX73_RS04110	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CNX73_RS04115	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CNX73_RS04125	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CNX73_RS04140	COG0328	RNA-DNA hybrid ribonuclease activity
CNX73_RS04160	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CNX73_RS04195	COG4974	Belongs to the 'phage' integrase family
CNX73_RS04205	COG0730	response to heat
CNX73_RS04215	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CNX73_RS04240	COG1338	Plays a role in the flagellum-specific transport system
CNX73_RS04250	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CNX73_RS04260	COG0183	Belongs to the thiolase family
CNX73_RS04265	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CNX73_RS04270	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CNX73_RS04275	COG2031	fatty acid transporter
CNX73_RS04290	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
CNX73_RS04295	COG4647	ligase activity
CNX73_RS04305	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CNX73_RS04310	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CNX73_RS04320	COG2204	response regulator
CNX73_RS04340	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CNX73_RS04360	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
CNX73_RS04385	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CNX73_RS04390	COG1137	ATPase activity
CNX73_RS04400	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CNX73_RS04405	COG1279	arginine transmembrane transporter activity
CNX73_RS04425	COG0252	asparaginase activity
CNX73_RS04430	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CNX73_RS04445	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CNX73_RS04450	COG0037	tRNA processing
CNX73_RS04490	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CNX73_RS04495	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CNX73_RS04500	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CNX73_RS04505	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CNX73_RS04520	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CNX73_RS04530	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CNX73_RS04540	COG0772	Belongs to the SEDS family
CNX73_RS04550	COG0564	pseudouridine synthase activity
CNX73_RS04560	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CNX73_RS04565	COG2884	Cell division ATP-binding protein ftsE
CNX73_RS04615	COG2056	Na+-H+ antiporter family
CNX73_RS04620	COG0534	Mate efflux family protein
CNX73_RS04640	COG0552	protein localization to endoplasmic reticulum
CNX73_RS04675	COG0746	molybdenum cofactor guanylyltransferase activity
CNX73_RS04680	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CNX73_RS04690	COG0860	N-Acetylmuramoyl-L-alanine amidase
CNX73_RS04700	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CNX73_RS04710	COG1758	RNA polymerase activity
CNX73_RS04715	COG0528	UMP kinase activity
CNX73_RS04725	COG1049	propionate catabolic process, 2-methylcitrate cycle
CNX73_RS04780	COG2217	Heavy metal translocating P-type atpase
CNX73_RS04785	COG0606	chelatase, subunit chli
CNX73_RS04795	COG0740	serine-type endopeptidase activity
CNX73_RS04815	COG0315	cyclic pyranopterin monophosphate synthase activity
CNX73_RS04820	COG0521	Mo-molybdopterin cofactor biosynthetic process
CNX73_RS04825	COG0314	molybdopterin synthase activity
CNX73_RS04845	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CNX73_RS04845	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CNX73_RS04865	COG0736	holo-[acyl-carrier-protein] synthase activity
CNX73_RS04870	COG1580	Controls the rotational direction of flagella during chemotaxis
CNX73_RS04890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CNX73_RS04895	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CNX73_RS04900	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CNX73_RS04905	COG1360	Flagellar Motor Protein
CNX73_RS04915	COG1732	Glycine betaine
CNX73_RS04920	COG1125	glycine betaine transport
CNX73_RS04920	COG0517	IMP dehydrogenase activity
CNX73_RS04935	COG0322	excinuclease ABC activity
CNX73_RS04940	COG0460	homoserine dehydrogenase
CNX73_RS04945	COG0792	nuclease activity
CNX73_RS04950	COG3118	belongs to the thioredoxin family
CNX73_RS04955	COG0492	ferredoxin-NADP+ reductase activity
CNX73_RS04965	COG0724	RNA recognition motif
CNX73_RS04975	COG0516	GMP reductase activity
CNX73_RS04975	COG0517	IMP dehydrogenase activity
CNX73_RS04985	COG0237	dephospho-CoA kinase activity
CNX73_RS05005	COG0776	regulation of translation
CNX73_RS05030	COG1086	Polysaccharide biosynthesis protein
CNX73_RS05035	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CNX73_RS05050	COG0351	phosphomethylpyrimidine kinase
CNX73_RS05055	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CNX73_RS05090	COG0671	phosphoesterase, PA-phosphatase related
CNX73_RS05100	COG0488	(ABC) transporter
CNX73_RS05105	COG0516	GMP reductase activity
CNX73_RS05120	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CNX73_RS05125	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CNX73_RS05135	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CNX73_RS05170	COG0375	protein maturation
CNX73_RS05175	COG1749	Flagellar hook protein flgE
CNX73_RS05185	COG2824	Alkylphosphonate utilization operon protein PhnA
CNX73_RS05200	COG0753	catalase activity
CNX73_RS05210	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CNX73_RS05270	COG1217	gtp-binding protein TYPA
CNX73_RS05375	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CNX73_RS05395	COG1028	Short-chain dehydrogenase reductase Sdr
CNX73_RS05405	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CNX73_RS05410	COG0833	amino acid
CNX73_RS05425	COG0745	RESPONSE REGULATOR receiver
CNX73_RS05445	COG0484	heat shock protein binding
CNX73_RS05450	COG0789	Transcriptional regulator
CNX73_RS05455	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CNX73_RS05455	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CNX73_RS05460	COG0735	belongs to the Fur family
CNX73_RS05475	COG1776	CheC inhibitor of MCP methylation
CNX73_RS05475	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CNX73_RS05480	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CNX73_RS05495	COG0455	bacterial-type flagellum organization
CNX73_RS05500	COG1419	protein localization to endoplasmic reticulum
CNX73_RS05505	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CNX73_RS05510	COG0006	proline dipeptidase activity
CNX73_RS05530	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CNX73_RS05535	COG2404	hydrolase activity, acting on ester bonds
CNX73_RS05545	COG0745	RESPONSE REGULATOR receiver
CNX73_RS05550	COG1408	metallophosphoesterase
CNX73_RS05570	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CNX73_RS05580	COG0083	homoserine kinase activity
CNX73_RS05635	COG0805	protein transport
CNX73_RS05640	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CNX73_RS05645	COG0357	Ribosomal RNA small subunit methyltransferase G
CNX73_RS05670	COG0745	RESPONSE REGULATOR receiver
CNX73_RS05675	COG2264	protein methyltransferase activity
CNX73_RS05680	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CNX73_RS05690	COG1183	phosphatidylcholine synthase activity
CNX73_RS05700	COG2608	mercury ion transmembrane transporter activity
CNX73_RS05720	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CNX73_RS05730	COG1106	Psort location Cytoplasmic, score
CNX73_RS05745	COG1132	(ABC) transporter
CNX73_RS05755	COG0540	Belongs to the ATCase OTCase family
CNX73_RS05765	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CNX73_RS05770	COG0196	riboflavin kinase activity
CNX73_RS05775	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CNX73_RS05785	COG1674	ftsk spoiiie
CNX73_RS05795	COG0477	Major facilitator Superfamily
CNX73_RS05800	COG4786	Flagellar basal body rod
CNX73_RS05830	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CNX73_RS05840	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CNX73_RS05845	COG1766	The M ring may be actively involved in energy transduction
CNX73_RS05855	COG0504	CTP synthase activity
CNX73_RS05860	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CNX73_RS05860	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CNX73_RS05865	COG0564	pseudouridine synthase activity
CNX73_RS05880	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CNX73_RS05890	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CNX73_RS05890	COG0758	DNA mediated transformation
CNX73_RS05900	COG2894	cell division
CNX73_RS05905	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CNX73_RS05925	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CNX73_RS05935	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CNX73_RS05960	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CNX73_RS05970	COG0748	coenzyme F420 binding
CNX73_RS05980	COG0523	cobalamin synthesis protein
CNX73_RS05990	COG0726	polysaccharide deacetylase
CNX73_RS05995	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CNX73_RS06030	COG4608	Belongs to the ABC transporter superfamily
CNX73_RS06035	COG0444	Belongs to the ABC transporter superfamily
CNX73_RS06040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CNX73_RS06045	COG0601	transmembrane transport
CNX73_RS06050	COG0747	negative chemotaxis
CNX73_RS06075	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CNX73_RS06090	COG0019	diaminopimelate decarboxylase activity
CNX73_RS06110	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CNX73_RS06115	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CNX73_RS06145	COG0859	PFAM glycosyl transferase family 9
CNX73_RS06150	COG0248	Ppx GppA phosphatase
CNX73_RS06160	COG0134	indole-3-glycerol-phosphate synthase activity
CNX73_RS06170	COG0727	PFAM Uncharacterised protein family (UPF0153)
CNX73_RS06195	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CNX73_RS06205	COG0402	S-adenosylhomocysteine deaminase activity
CNX73_RS06210	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CNX73_RS06215	COG0785	Cytochrome C biogenesis protein
CNX73_RS06220	COG0542	response to heat
CNX73_RS06250	COG0750	zinc metalloprotease
CNX73_RS06285	COG4239	(ABC) transporter, permease
CNX73_RS06290	COG4172	Belongs to the ABC transporter superfamily
CNX73_RS06310	COG1706	bacterial-type flagellum-dependent cell motility
CNX73_RS06315	COG3951	Flagellar rod assembly protein muramidase FlgJ
CNX73_RS06320	COG0642	Histidine kinase
CNX73_RS06325	COG0783	Belongs to the Dps family
CNX73_RS06365	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CNX73_RS06375	COG0754	glutathionylspermidine amidase activity
CNX73_RS06390	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CNX73_RS06405	COG0659	secondary active sulfate transmembrane transporter activity
CNX73_RS06415	COG0730	response to heat
CNX73_RS06420	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CNX73_RS06420	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CNX73_RS06425	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CNX73_RS06455	COG1881	PFAM PEBP family protein
CNX73_RS06465	COG0575	Belongs to the CDS family
CNX73_RS06470	COG0471	metal ion transport
CNX73_RS06480	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CNX73_RS06485	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CNX73_RS06490	COG0326	Molecular chaperone. Has ATPase activity
CNX73_RS06505	COG0489	protein tyrosine kinase activity
CNX73_RS06530	COG0416	fatty acid biosynthetic process
CNX73_RS06550	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CNX73_RS06560	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CNX73_RS06575	COG1053	succinate dehydrogenase
CNX73_RS06580	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CNX73_RS06585	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CNX73_RS06635	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CNX73_RS06640	COG1136	(ABC) transporter
CNX73_RS06645	COG2089	acid synthase
CNX73_RS06655	COG0191	fructose-bisphosphate aldolase activity
CNX73_RS06660	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CNX73_RS06680	COG0303	'Molybdopterin
CNX73_RS06695	COG0826	peptidase U32
CNX73_RS06710	COG0745	RESPONSE REGULATOR receiver
CNX73_RS06720	COG0113	porphobilinogen synthase activity
CNX73_RS06725	COG0217	transcriptional regulatory protein
CNX73_RS06730	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CNX73_RS06760	COG0148	phosphopyruvate hydratase activity
CNX73_RS06810	COG3278	Belongs to the heme-copper respiratory oxidase family
CNX73_RS06815	COG0471	metal ion transport
CNX73_RS06820	COG1194	a g-specific adenine glycosylase
CNX73_RS06825	COG1620	l-lactate permease
CNX73_RS06830	COG1620	l-lactate permease
CNX73_RS06835	COG0247	lactate metabolic process
CNX73_RS06840	COG1139	Iron-sulfur cluster binding protein
CNX73_RS06850	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CNX73_RS06860	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CNX73_RS06865	COG0814	amino acid
CNX73_RS06870	COG1760	l-serine dehydratase
CNX73_RS06925	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CNX73_RS06940	COG0574	Belongs to the PEP-utilizing enzyme family
CNX73_RS06940	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CNX73_RS06950	COG0731	radical SAM domain protein
CNX73_RS06955	COG0551	DNA topoisomerase type I activity
CNX73_RS06955	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CNX73_RS06960	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CNX73_RS06980	COG1420	regulation of RNA biosynthetic process
CNX73_RS06985	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CNX73_RS07000	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CNX73_RS07005	COG0626	cystathionine gamma-synthase activity
CNX73_RS07010	COG1854	S-ribosylhomocysteine lyase activity
CNX73_RS07015	COG0737	Belongs to the 5'-nucleotidase family
CNX73_RS07035	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CNX73_RS07040	COG0840	transmembrane signaling receptor activity
CNX73_RS07045	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CNX73_RS07055	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CNX73_RS07085	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CNX73_RS07090	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CNX73_RS07095	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CNX73_RS07105	COG0579	oxidoreductase
CNX73_RS07130	COG0840	transmembrane signaling receptor activity
CNX73_RS07155	COG0268	Binds directly to 16S ribosomal RNA
CNX73_RS07160	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CNX73_RS07165	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CNX73_RS07265	COG0506	proline dehydrogenase activity
CNX73_RS07265	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CNX73_RS07265	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CNX73_RS07270	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CNX73_RS07320	COG0157	Belongs to the NadC ModD family
CNX73_RS07345	COG0109	protoheme IX farnesyltransferase activity
CNX73_RS07355	COG0305	Participates in initiation and elongation during chromosome replication
CNX73_RS07360	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CNX73_RS07360	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CNX73_RS07365	COG0642	Histidine kinase
CNX73_RS07370	COG0745	RESPONSE REGULATOR receiver
CNX73_RS07385	COG1792	Involved in formation and maintenance of cell shape
CNX73_RS07390	COG1077	Cell shape determining protein MreB Mrl
CNX73_RS07395	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CNX73_RS07400	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CNX73_RS07405	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CNX73_RS07420	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CNX73_RS07425	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CNX73_RS07430	COG0287	Prephenate dehydrogenase
CNX73_RS07440	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CNX73_RS07445	COG3421	Type III restriction
CNX73_RS07455	COG1295	ribonuclease BN
CNX73_RS07495	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CNX73_RS07500	COG0799	negative regulation of ribosome biogenesis
CNX73_RS07505	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CNX73_RS07525	COG2957	Belongs to the agmatine deiminase family
CNX73_RS07530	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CNX73_RS07545	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CNX73_RS07595	COG0542	response to heat
CNX73_RS07600	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CNX73_RS07605	COG0589	response to stress
CNX73_RS07615	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CNX73_RS07625	COG0538	isocitrate dehydrogenase activity
CNX73_RS07630	COG0372	Belongs to the citrate synthase family
CNX73_RS07650	COG2194	sulfuric ester hydrolase activity
CNX73_RS07655	COG0671	phosphoesterase, PA-phosphatase related
CNX73_RS07665	COG0784	Response regulator, receiver
CNX73_RS07665	COG0835	chemotaxis
CNX73_RS07700	COG0482	sulfurtransferase activity
CNX73_RS07705	COG0358	DNA primase activity
CNX73_RS07715	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CNX73_RS07720	COG0459	protein refolding
CNX73_RS07765	COG0288	reversible hydration of carbon dioxide
CNX73_RS07770	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CNX73_RS07790	COG4735	regulation of single-species biofilm formation
CNX73_RS07810	COG4786	Flagellar basal body rod
CNX73_RS07815	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CNX73_RS07825	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CNX73_RS07830	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CNX73_RS07835	COG0671	phosphoesterase, PA-phosphatase related
CNX73_RS07845	COG2011	ABC-type metal ion transport system permease component
CNX73_RS07860	COG0307	riboflavin synthase, alpha
CNX73_RS07865	COG0084	hydrolase, TatD family'
CNX73_RS07870	COG0741	lytic transglycosylase activity
CNX73_RS07870	COG1388	LysM domain
CNX73_RS07875	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CNX73_RS07880	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CNX73_RS07905	COG0768	penicillin binding
CNX73_RS07915	COG0450	alkyl hydroperoxide reductase
CNX73_RS07930	COG0772	Belongs to the SEDS family
CNX73_RS07935	COG1815	bacterial-type flagellum-dependent cell motility
CNX73_RS07940	COG1558	bacterial-type flagellum-dependent cell motility
CNX73_RS07955	COG0768	penicillin binding
CNX73_RS07980	COG0723	plastoquinol--plastocyanin reductase activity
CNX73_RS07985	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CNX73_RS07995	COG0739	heme binding
CNX73_RS08005	COG0285	dihydrofolate synthase activity
CNX73_RS08025	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CNX73_RS08030	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CNX73_RS08035	COG1862	Preprotein translocase
CNX73_RS08040	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CNX73_RS08045	COG1074	ATP-dependent DNA helicase activity
CNX73_RS08080	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CNX73_RS08090	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CNX73_RS08105	COG0497	DNA recombination
CNX73_RS08125	COG0686	Belongs to the AlaDH PNT family
CNX73_RS08130	COG0010	Belongs to the arginase family
CNX73_RS08145	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CNX73_RS08170	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
CNX73_RS08175	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity