locus-tag	class	description
AXW69_RS00010	COG1295	ribonuclease BN
AXW69_RS00020	COG3421	Type III restriction
AXW69_RS00025	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AXW69_RS00035	COG0372	Belongs to the citrate synthase family
AXW69_RS00040	COG0538	isocitrate dehydrogenase activity
AXW69_RS00060	COG0589	response to stress
AXW69_RS00065	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AXW69_RS00070	COG0542	response to heat
AXW69_RS00115	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AXW69_RS00130	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AXW69_RS00135	COG2957	Belongs to the agmatine deiminase family
AXW69_RS00145	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AXW69_RS00150	COG0848	biopolymer transport protein
AXW69_RS00155	COG0811	peptide transport
AXW69_RS00160	COG0864	Transcriptional regulator
AXW69_RS00190	COG0484	heat shock protein binding
AXW69_RS00195	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AXW69_RS00200	COG1687	branched-chain amino acid
AXW69_RS00205	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AXW69_RS00225	COG0114	fumarate hydratase activity
AXW69_RS00255	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AXW69_RS00280	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AXW69_RS00295	COG0255	Belongs to the universal ribosomal protein uL29 family
AXW69_RS00315	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AXW69_RS00350	COG0201	protein transport
AXW69_RS00355	COG0024	Methionine aminopeptidase
AXW69_RS00360	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AXW69_RS00385	COG0202	RNA polymerase activity
AXW69_RS00405	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AXW69_RS00410	COG2353	YceI-like domain
AXW69_RS00420	COG0859	PFAM glycosyl transferase family 9
AXW69_RS00425	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AXW69_RS00430	COG0512	Glutamine amidotransferase of anthranilate synthase
AXW69_RS00435	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AXW69_RS00440	COG0135	phosphoribosylanthranilate isomerase activity
AXW69_RS00440	COG0134	indole-3-glycerol-phosphate synthase activity
AXW69_RS00445	COG0133	tryptophan synthase activity
AXW69_RS00470	COG1007	ATP synthesis coupled electron transport
AXW69_RS00480	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AXW69_RS00485	COG0713	ATP synthesis coupled electron transport
AXW69_RS00490	COG0839	Belongs to the complex I subunit 6 family
AXW69_RS00525	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AXW69_RS00535	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AXW69_RS00540	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AXW69_RS00560	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AXW69_RS00570	COG0180	Tryptophanyl-tRNA synthetase
AXW69_RS00575	COG4166	transmembrane transport
AXW69_RS00580	COG4174	ABC transporter (Permease)
AXW69_RS00600	COG1466	dna polymerase III delta subunit
AXW69_RS00610	COG0629	single-stranded DNA binding
AXW69_RS00660	COG0505	Belongs to the CarA family
AXW69_RS00675	COG0697	spore germination
AXW69_RS00685	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AXW69_RS00700	COG0527	aspartate kinase activity
AXW69_RS00710	COG2863	cytochrome
AXW69_RS00715	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AXW69_RS00740	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AXW69_RS00745	COG1131	(ABC) transporter
AXW69_RS00755	COG0151	Belongs to the GarS family
AXW69_RS00765	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AXW69_RS00795	COG1045	serine acetyltransferase
AXW69_RS00815	COG1132	(ABC) transporter
AXW69_RS00860	COG0250	Participates in transcription elongation, termination and antitermination
AXW69_RS00910	COG0859	PFAM glycosyl transferase family 9
AXW69_RS00920	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AXW69_RS00935	COG2814	Major facilitator Superfamily
AXW69_RS00945	COG0475	glutathione-regulated potassium exporter activity
AXW69_RS00945	COG0569	domain protein
AXW69_RS00950	COG0037	tRNA processing
AXW69_RS00955	COG2814	Major facilitator Superfamily
AXW69_RS00965	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AXW69_RS00985	COG2252	PERMEase
AXW69_RS00990	COG0738	Major facilitator superfamily
AXW69_RS01005	COG1126	abc transporter atp-binding protein
AXW69_RS01010	COG0765	amino acid transport
AXW69_RS01020	COG1966	Carbon starvation protein
AXW69_RS01030	COG0166	Belongs to the GPI family
AXW69_RS01040	COG0492	ferredoxin-NADP+ reductase activity
AXW69_RS01055	COG0716	FMN binding
AXW69_RS01075	COG2184	nucleotidyltransferase activity
AXW69_RS01080	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AXW69_RS01105	COG0525	valine-tRNA ligase activity
AXW69_RS01130	COG0336	Belongs to the RNA methyltransferase TrmD family
AXW69_RS01165	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AXW69_RS01175	COG1192	Involved in chromosome partitioning
AXW69_RS01180	COG1475	DNA binding
AXW69_RS01210	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AXW69_RS01220	COG0811	peptide transport
AXW69_RS01225	COG0848	biopolymer transport protein
AXW69_RS01235	COG0823	Involved in the tonB-independent uptake of proteins
AXW69_RS01240	COG2885	chlorophyll binding
AXW69_RS01250	COG1047	Peptidyl-prolyl cis-trans
AXW69_RS01280	COG0405	Gamma-glutamyltransferase
AXW69_RS01310	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AXW69_RS01320	COG0674	pyruvate-flavodoxin oxidoreductase activity
AXW69_RS01330	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AXW69_RS01355	COG1064	alcohol dehydrogenase
AXW69_RS01365	COG0363	glucosamine-6-phosphate deaminase activity
AXW69_RS01370	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AXW69_RS01375	COG0129	dihydroxy-acid dehydratase activity
AXW69_RS01380	COG0800	Aldolase
AXW69_RS01385	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AXW69_RS01390	COG4221	oxidoreductase activity
AXW69_RS01415	COG0101	tRNA pseudouridine synthase activity
AXW69_RS01425	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AXW69_RS01430	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AXW69_RS01440	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AXW69_RS01460	COG0439	Biotin carboxylase
AXW69_RS01465	COG0511	ligase activity, forming carbon-carbon bonds
AXW69_RS01480	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AXW69_RS01500	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AXW69_RS01500	COG1333	cytochrome c biogenesis protein
AXW69_RS01510	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AXW69_RS01515	COG2890	protein-(glutamine-N5) methyltransferase activity
AXW69_RS01520	COG0501	Belongs to the peptidase M48B family
AXW69_RS01545	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AXW69_RS01555	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AXW69_RS01560	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AXW69_RS01565	COG0835	chemotaxis
AXW69_RS01570	COG0784	Response regulator, receiver
AXW69_RS01570	COG2198	Histidine kinase
AXW69_RS01570	COG0643	Histidine kinase
AXW69_RS01575	COG0784	Response regulator, receiver
AXW69_RS01575	COG0835	chemotaxis
AXW69_RS01585	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AXW69_RS01590	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AXW69_RS01595	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AXW69_RS01620	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AXW69_RS01620	COG0072	phenylalanine-tRNA ligase activity
AXW69_RS01630	COG0537	adenosine 5'-monophosphoramidase activity
AXW69_RS01635	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AXW69_RS01700	COG0668	transmembrane transport
AXW69_RS01705	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AXW69_RS01710	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AXW69_RS01710	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AXW69_RS01735	COG1166	arginine decarboxylase activity
AXW69_RS01785	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AXW69_RS01790	COG0849	cell division
AXW69_RS01800	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AXW69_RS01805	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AXW69_RS01810	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AXW69_RS01875	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AXW69_RS01890	COG0564	pseudouridine synthase activity
AXW69_RS01910	COG1058	Belongs to the CinA family
AXW69_RS01910	COG1546	Belongs to the CinA family
AXW69_RS01920	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AXW69_RS01940	COG1757	Na H antiporter
AXW69_RS01970	COG0251	oxidation-reduction process
AXW69_RS01975	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXW69_RS01980	COG1115	amino acid carrier protein
AXW69_RS01990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXW69_RS01995	COG0765	amino acid transport
AXW69_RS02025	COG0602	queuosine metabolic process
AXW69_RS02030	COG0720	synthase
AXW69_RS02045	COG0142	geranyltranstransferase activity
AXW69_RS02070	COG1942	4-Oxalocrotonate Tautomerase
AXW69_RS02090	COG0670	Belongs to the BI1 family
AXW69_RS02095	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AXW69_RS02140	COG1749	Flagellar hook protein flgE
AXW69_RS02140	COG1749	Flagellar hook protein flgE
AXW69_RS02145	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AXW69_RS02155	COG0280	phosphate acetyltransferase
AXW69_RS02175	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AXW69_RS02180	COG0298	carbon dioxide binding
AXW69_RS02185	COG0409	Hydrogenase expression formation protein
AXW69_RS02215	COG3041	Addiction module toxin RelE StbE family
AXW69_RS02220	COG1607	acyl-coa hydrolase
AXW69_RS02225	COG0300	oxidoreductase activity
AXW69_RS02230	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AXW69_RS02235	COG1120	ATPase activity
AXW69_RS02250	COG0728	peptidoglycan biosynthetic process
AXW69_RS02290	COG0753	catalase activity
AXW69_RS02305	COG2824	Alkylphosphonate utilization operon protein PhnA
AXW69_RS02310	COG2134	cdp-diacylglycerol pyrophosphatase
AXW69_RS02315	COG1749	Flagellar hook protein flgE
AXW69_RS02320	COG0375	protein maturation
AXW69_RS02335	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AXW69_RS02340	COG0756	dUTP diphosphatase activity
AXW69_RS02355	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AXW69_RS02365	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AXW69_RS02370	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AXW69_RS02375	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AXW69_RS02375	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AXW69_RS02380	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AXW69_RS02390	COG0488	(ABC) transporter
AXW69_RS02400	COG0671	phosphoesterase, PA-phosphatase related
AXW69_RS02425	COG0351	phosphomethylpyrimidine kinase
AXW69_RS02440	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AXW69_RS02445	COG1086	Polysaccharide biosynthesis protein
AXW69_RS02470	COG0776	regulation of translation
AXW69_RS02490	COG0237	dephospho-CoA kinase activity
AXW69_RS02500	COG0517	IMP dehydrogenase activity
AXW69_RS02500	COG0516	GMP reductase activity
AXW69_RS02510	COG0724	RNA recognition motif
AXW69_RS02520	COG0492	ferredoxin-NADP+ reductase activity
AXW69_RS02525	COG3118	belongs to the thioredoxin family
AXW69_RS02535	COG0460	homoserine dehydrogenase
AXW69_RS02555	COG1125	glycine betaine transport
AXW69_RS02555	COG0517	IMP dehydrogenase activity
AXW69_RS02570	COG1360	Flagellar Motor Protein
AXW69_RS02575	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AXW69_RS02580	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AXW69_RS02585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AXW69_RS02605	COG1580	Controls the rotational direction of flagella during chemotaxis
AXW69_RS02610	COG0736	holo-[acyl-carrier-protein] synthase activity
AXW69_RS02635	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AXW69_RS02635	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AXW69_RS02660	COG0521	Mo-molybdopterin cofactor biosynthetic process
AXW69_RS02695	COG0606	chelatase, subunit chli
AXW69_RS02700	COG2217	Heavy metal translocating P-type atpase
AXW69_RS02730	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AXW69_RS02760	COG1049	propionate catabolic process, 2-methylcitrate cycle
AXW69_RS02775	COG1758	RNA polymerase activity
AXW69_RS02780	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AXW69_RS02785	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AXW69_RS02790	COG0126	phosphoglycerate kinase activity
AXW69_RS02795	COG0860	N-Acetylmuramoyl-L-alanine amidase
AXW69_RS02805	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AXW69_RS02820	COG0552	protein localization to endoplasmic reticulum
AXW69_RS02845	COG2056	Na+-H+ antiporter family
AXW69_RS02875	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AXW69_RS02895	COG2884	Cell division ATP-binding protein ftsE
AXW69_RS02900	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AXW69_RS02920	COG0772	Belongs to the SEDS family
AXW69_RS02930	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AXW69_RS02940	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AXW69_RS02955	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AXW69_RS02960	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AXW69_RS02965	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AXW69_RS03000	COG0037	tRNA processing
AXW69_RS03005	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AXW69_RS03020	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AXW69_RS03025	COG0252	asparaginase activity
AXW69_RS03040	COG1279	arginine transmembrane transporter activity
AXW69_RS03045	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AXW69_RS03055	COG1137	ATPase activity
AXW69_RS03060	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AXW69_RS03075	COG0617	tRNA 3'-terminal CCA addition
AXW69_RS03090	COG0778	Nitroreductase
AXW69_RS03100	COG0762	integral membrane protein
AXW69_RS03125	COG1027	Aspartate ammonia-lyase
AXW69_RS03140	COG0560	Phosphoserine phosphatase
AXW69_RS03145	COG1528	Iron-storage protein
AXW69_RS03150	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AXW69_RS03155	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AXW69_RS03160	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AXW69_RS03185	COG0328	RNA-DNA hybrid ribonuclease activity
AXW69_RS03190	COG0571	ribonuclease III activity
AXW69_RS03205	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AXW69_RS03240	COG4974	Belongs to the 'phage' integrase family
AXW69_RS03260	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AXW69_RS03280	COG1338	Plays a role in the flagellum-specific transport system
AXW69_RS03290	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AXW69_RS03300	COG0183	Belongs to the thiolase family
AXW69_RS03305	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AXW69_RS03310	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AXW69_RS03315	COG2031	fatty acid transporter
AXW69_RS03325	COG0145	ligase activity
AXW69_RS03330	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
AXW69_RS03335	COG4647	ligase activity
AXW69_RS03350	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AXW69_RS03355	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AXW69_RS03370	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AXW69_RS03390	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
AXW69_RS03415	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AXW69_RS03420	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AXW69_RS03425	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
AXW69_RS03430	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AXW69_RS03440	COG2249	NAD(P)H dehydrogenase (quinone) activity
AXW69_RS03455	COG2171	N-acyltransferase activity
AXW69_RS03465	COG0436	Aminotransferase
AXW69_RS03485	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AXW69_RS03500	COG3306	glycosyltransferase involved in LPS biosynthesis
AXW69_RS03510	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AXW69_RS03515	COG0784	Response regulator, receiver
AXW69_RS03515	COG0835	chemotaxis
AXW69_RS03530	COG1136	(ABC) transporter
AXW69_RS03580	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AXW69_RS03590	COG0840	transmembrane signaling receptor activity
AXW69_RS03595	COG0156	8-amino-7-oxononanoate synthase activity
AXW69_RS03600	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AXW69_RS03630	COG1013	pyruvate-flavodoxin oxidoreductase activity
AXW69_RS03635	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AXW69_RS03635	COG0674	pyruvate-flavodoxin oxidoreductase activity
AXW69_RS03655	COG1918	ferrous iron import across plasma membrane
AXW69_RS03660	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AXW69_RS03665	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AXW69_RS03665	COG1776	CheC inhibitor of MCP methylation
AXW69_RS03705	COG0681	Belongs to the peptidase S26 family
AXW69_RS03710	COG1994	Peptidase M50
AXW69_RS03715	COG0698	ribose 5-phosphate isomerase
AXW69_RS03740	COG0012	GTP binding
AXW69_RS03750	COG0628	permease
AXW69_RS03780	COG1028	Short-chain dehydrogenase reductase Sdr
AXW69_RS03790	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AXW69_RS03820	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AXW69_RS03830	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AXW69_RS03840	COG1842	Phage shock protein A
AXW69_RS03860	COG3451	type IV secretory pathway VirB4
AXW69_RS04035	COG0174	glutamine synthetase
AXW69_RS04050	COG0277	FAD linked oxidase domain protein
AXW69_RS04065	COG0739	heme binding
AXW69_RS04065	COG0741	lytic transglycosylase activity
AXW69_RS04065	COG1196	nuclear chromosome segregation
AXW69_RS04080	COG0187	DNA topoisomerase II activity
AXW69_RS04085	COG0592	DNA-directed DNA polymerase activity
AXW69_RS04095	COG0733	neurotransmitter:sodium symporter activity
AXW69_RS04100	COG0733	neurotransmitter:sodium symporter activity
AXW69_RS04105	COG0824	Thioesterase
AXW69_RS04175	COG1217	gtp-binding protein TYPA
AXW69_RS04275	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AXW69_RS04295	COG1028	Short-chain dehydrogenase reductase Sdr
AXW69_RS04305	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AXW69_RS04310	COG0833	amino acid
AXW69_RS04325	COG0745	RESPONSE REGULATOR receiver
AXW69_RS04340	COG0484	heat shock protein binding
AXW69_RS04345	COG0789	Transcriptional regulator
AXW69_RS04350	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AXW69_RS04350	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AXW69_RS04355	COG0735	belongs to the Fur family
AXW69_RS04370	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AXW69_RS04370	COG1776	CheC inhibitor of MCP methylation
AXW69_RS04375	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AXW69_RS04390	COG0455	bacterial-type flagellum organization
AXW69_RS04395	COG1419	protein localization to endoplasmic reticulum
AXW69_RS04400	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AXW69_RS04405	COG0006	proline dipeptidase activity
AXW69_RS04425	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AXW69_RS04430	COG2404	hydrolase activity, acting on ester bonds
AXW69_RS04435	COG0745	RESPONSE REGULATOR receiver
AXW69_RS04470	COG0083	homoserine kinase activity
AXW69_RS04480	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AXW69_RS04525	COG0805	protein transport
AXW69_RS04535	COG0357	Ribosomal RNA small subunit methyltransferase G
AXW69_RS04560	COG0745	RESPONSE REGULATOR receiver
AXW69_RS04570	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AXW69_RS04580	COG1183	phosphatidylcholine synthase activity
AXW69_RS04585	COG2217	Heavy metal translocating P-type atpase
AXW69_RS04590	COG2217	Heavy metal translocating P-type atpase
AXW69_RS04595	COG2608	mercury ion transmembrane transporter activity
AXW69_RS04615	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
AXW69_RS04635	COG1132	(ABC) transporter
AXW69_RS04655	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AXW69_RS04660	COG0196	riboflavin kinase activity
AXW69_RS04665	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AXW69_RS04675	COG1674	ftsk spoiiie
AXW69_RS04680	COG0477	Major facilitator Superfamily
AXW69_RS04685	COG4786	Flagellar basal body rod
AXW69_RS04705	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AXW69_RS04715	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AXW69_RS04730	COG0504	CTP synthase activity
AXW69_RS04735	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AXW69_RS04735	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AXW69_RS04740	COG0564	pseudouridine synthase activity
AXW69_RS04790	COG0758	DNA mediated transformation
AXW69_RS04790	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AXW69_RS04795	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AXW69_RS04800	COG2894	cell division
AXW69_RS04820	COG1663	tetraacyldisaccharide 4'-kinase activity
AXW69_RS04825	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AXW69_RS04830	COG3980	spore coat polysaccharide biosynthesis protein
AXW69_RS04835	COG3980	spore coat polysaccharide biosynthesis protein
AXW69_RS04840	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AXW69_RS04875	COG0748	coenzyme F420 binding
AXW69_RS04885	COG0523	cobalamin synthesis protein
AXW69_RS04905	COG0726	polysaccharide deacetylase
AXW69_RS04910	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AXW69_RS04945	COG4608	Belongs to the ABC transporter superfamily
AXW69_RS04950	COG0444	Belongs to the ABC transporter superfamily
AXW69_RS04955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXW69_RS04960	COG0601	transmembrane transport
AXW69_RS04965	COG0747	negative chemotaxis
AXW69_RS04990	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AXW69_RS05005	COG0019	diaminopimelate decarboxylase activity
AXW69_RS05025	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AXW69_RS05030	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AXW69_RS05060	COG0859	PFAM glycosyl transferase family 9
AXW69_RS05065	COG0248	Ppx GppA phosphatase
AXW69_RS05075	COG0134	indole-3-glycerol-phosphate synthase activity
AXW69_RS05085	COG0727	PFAM Uncharacterised protein family (UPF0153)
AXW69_RS05120	COG0402	S-adenosylhomocysteine deaminase activity
AXW69_RS05125	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AXW69_RS05130	COG0785	Cytochrome C biogenesis protein
AXW69_RS05135	COG0542	response to heat
AXW69_RS05165	COG0750	zinc metalloprotease
AXW69_RS05200	COG4239	(ABC) transporter, permease
AXW69_RS05205	COG4172	Belongs to the ABC transporter superfamily
AXW69_RS05230	COG3951	Flagellar rod assembly protein muramidase FlgJ
AXW69_RS05235	COG0642	Histidine kinase
AXW69_RS05240	COG0783	Belongs to the Dps family
AXW69_RS05280	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AXW69_RS05290	COG0754	glutathionylspermidine amidase activity
AXW69_RS05320	COG0659	secondary active sulfate transmembrane transporter activity
AXW69_RS05330	COG0730	response to heat
AXW69_RS05340	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AXW69_RS05340	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AXW69_RS05345	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AXW69_RS05360	COG1104	cysteine desulfurase activity
AXW69_RS05370	COG1881	PFAM PEBP family protein
AXW69_RS05390	COG0575	Belongs to the CDS family
AXW69_RS05395	COG0471	metal ion transport
AXW69_RS05410	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AXW69_RS05415	COG0326	Molecular chaperone. Has ATPase activity
AXW69_RS05435	COG0489	protein tyrosine kinase activity
AXW69_RS05450	COG4974	Belongs to the 'phage' integrase family
AXW69_RS05530	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AXW69_RS05555	COG4962	Type ii secretion system protein e
AXW69_RS05670	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AXW69_RS05675	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AXW69_RS05690	COG1053	succinate dehydrogenase
AXW69_RS05695	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AXW69_RS05700	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AXW69_RS05745	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AXW69_RS05750	COG1136	(ABC) transporter
AXW69_RS05755	COG2089	acid synthase
AXW69_RS05765	COG0191	fructose-bisphosphate aldolase activity
AXW69_RS05770	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AXW69_RS05800	COG0826	peptidase U32
AXW69_RS05815	COG0745	RESPONSE REGULATOR receiver
AXW69_RS05825	COG0113	porphobilinogen synthase activity
AXW69_RS05835	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AXW69_RS05920	COG0471	metal ion transport
AXW69_RS05930	COG1620	l-lactate permease
AXW69_RS05935	COG1620	l-lactate permease
AXW69_RS05940	COG0247	lactate metabolic process
AXW69_RS05945	COG1139	Iron-sulfur cluster binding protein
AXW69_RS05955	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AXW69_RS05970	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AXW69_RS05975	COG0814	amino acid
AXW69_RS05980	COG1760	l-serine dehydratase
AXW69_RS06020	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AXW69_RS06035	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AXW69_RS06035	COG0574	Belongs to the PEP-utilizing enzyme family
AXW69_RS06050	COG0731	radical SAM domain protein
AXW69_RS06055	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AXW69_RS06055	COG0551	DNA topoisomerase type I activity
AXW69_RS06060	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AXW69_RS06080	COG1420	regulation of RNA biosynthetic process
AXW69_RS06095	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AXW69_RS06100	COG0626	cystathionine gamma-synthase activity
AXW69_RS06110	COG0737	Belongs to the 5'-nucleotidase family
AXW69_RS06120	COG1216	Glycosyl transferase, family 2
AXW69_RS06130	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AXW69_RS06135	COG0840	transmembrane signaling receptor activity
AXW69_RS06140	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AXW69_RS06150	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AXW69_RS06185	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AXW69_RS06190	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AXW69_RS06195	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AXW69_RS06225	COG0840	transmembrane signaling receptor activity
AXW69_RS06260	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AXW69_RS06270	COG0832	Belongs to the urease beta subunit family
AXW69_RS06270	COG0831	urea catabolic process
AXW69_RS06290	COG0830	nickel cation binding
AXW69_RS06360	COG0506	proline dehydrogenase activity
AXW69_RS06360	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AXW69_RS06360	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AXW69_RS06365	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AXW69_RS06535	COG0861	Integral membrane protein TerC family
AXW69_RS06540	COG0598	Magnesium transport protein CorA
AXW69_RS06545	COG0126	phosphoglycerate kinase activity
AXW69_RS06550	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AXW69_RS06560	COG0204	Acyl-transferase
AXW69_RS06570	COG0793	Belongs to the peptidase S41A family
AXW69_RS06595	COG0157	Belongs to the NadC ModD family
AXW69_RS06600	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AXW69_RS06620	COG0109	protoheme IX farnesyltransferase activity
AXW69_RS06630	COG0305	Participates in initiation and elongation during chromosome replication
AXW69_RS06635	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AXW69_RS06635	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AXW69_RS06640	COG0642	Histidine kinase
AXW69_RS06645	COG0745	RESPONSE REGULATOR receiver
AXW69_RS06650	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AXW69_RS06665	COG1077	Cell shape determining protein MreB Mrl
AXW69_RS06670	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AXW69_RS06680	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AXW69_RS06685	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
AXW69_RS06695	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AXW69_RS06700	COG0287	Prephenate dehydrogenase
AXW69_RS06720	COG2194	sulfuric ester hydrolase activity
AXW69_RS06725	COG0671	phosphoesterase, PA-phosphatase related
AXW69_RS06735	COG0835	chemotaxis
AXW69_RS06735	COG0784	Response regulator, receiver
AXW69_RS06770	COG0482	sulfurtransferase activity
AXW69_RS06775	COG0358	DNA primase activity
AXW69_RS06785	COG0459	protein refolding
AXW69_RS06830	COG0288	reversible hydration of carbon dioxide
AXW69_RS06850	COG4735	regulation of single-species biofilm formation
AXW69_RS06855	COG4786	Flagellar basal body rod
AXW69_RS06890	COG0671	phosphoesterase, PA-phosphatase related
AXW69_RS06900	COG2011	ABC-type metal ion transport system permease component
AXW69_RS06915	COG0307	riboflavin synthase, alpha
AXW69_RS06920	COG0084	hydrolase, TatD family'
AXW69_RS06925	COG1388	LysM domain
AXW69_RS06925	COG0741	lytic transglycosylase activity
AXW69_RS06930	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AXW69_RS06935	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AXW69_RS06960	COG0768	penicillin binding
AXW69_RS06970	COG0450	alkyl hydroperoxide reductase
AXW69_RS06985	COG0772	Belongs to the SEDS family
AXW69_RS06990	COG1815	bacterial-type flagellum-dependent cell motility
AXW69_RS06995	COG1558	bacterial-type flagellum-dependent cell motility
AXW69_RS07005	COG0768	penicillin binding
AXW69_RS07030	COG0723	plastoquinol--plastocyanin reductase activity
AXW69_RS07035	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AXW69_RS07045	COG0739	heme binding
AXW69_RS07055	COG0285	dihydrofolate synthase activity
AXW69_RS07065	COG0495	leucyl-tRNA aminoacylation
AXW69_RS07075	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AXW69_RS07080	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AXW69_RS07085	COG1862	Preprotein translocase
AXW69_RS07095	COG1074	ATP-dependent DNA helicase activity
AXW69_RS07135	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AXW69_RS07160	COG0497	DNA recombination
AXW69_RS07190	COG0010	Belongs to the arginase family
AXW69_RS07205	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AXW69_RS07215	COG0732	type I restriction modification DNA specificity domain
AXW69_RS07220	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
AXW69_RS07225	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AXW69_RS07255	COG0708	Exodeoxyribonuclease III
AXW69_RS07270	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AXW69_RS07300	COG0195	Participates in both transcription termination and antitermination
AXW69_RS07305	COG1921	L-seryl-tRNASec selenium transferase activity
AXW69_RS07325	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AXW69_RS07340	COG0786	glutamate:sodium symporter activity
AXW69_RS07350	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AXW69_RS07400	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AXW69_RS07410	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AXW69_RS07420	COG1253	flavin adenine dinucleotide binding
AXW69_RS07430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXW69_RS07445	COG1739	Uncharacterized protein family UPF0029
AXW69_RS07450	COG1981	membrane
AXW69_RS07455	COG2226	methyltransferase
AXW69_RS07490	COG0163	prenyltransferase activity
AXW69_RS07495	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AXW69_RS07525	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AXW69_RS07525	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AXW69_RS07535	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AXW69_RS07545	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AXW69_RS07550	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AXW69_RS07575	COG0587	DNA-directed DNA polymerase activity
AXW69_RS07580	COG1187	pseudouridine synthase activity
AXW69_RS07585	COG3118	belongs to the thioredoxin family
AXW69_RS07625	COG0706	membrane insertase activity
AXW69_RS07645	COG0848	biopolymer transport protein
AXW69_RS07650	COG0811	peptide transport
AXW69_RS07660	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AXW69_RS07670	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AXW69_RS07715	COG0616	signal peptide processing
AXW69_RS07720	COG0788	formyltetrahydrofolate deformylase activity
AXW69_RS07750	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AXW69_RS07755	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AXW69_RS07755	COG0517	IMP dehydrogenase activity
AXW69_RS07775	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AXW69_RS07785	COG4962	Type ii secretion system protein e
AXW69_RS07790	COG1157	protein secretion by the type III secretion system
AXW69_RS07795	COG1987	bacterial-type flagellum assembly
AXW69_RS07800	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AXW69_RS07825	COG0799	negative regulation of ribosome biogenesis