locus-tag	class	description
HG566_RS00020	COG0288	reversible hydration of carbon dioxide
HG566_RS00070	COG0358	DNA primase activity
HG566_RS00075	COG0482	sulfurtransferase activity
HG566_RS00110	COG0835	chemotaxis
HG566_RS00110	COG0784	Response regulator, receiver
HG566_RS00120	COG0671	phosphoesterase, PA-phosphatase related
HG566_RS00125	COG2194	sulfuric ester hydrolase activity
HG566_RS00135	COG0372	Belongs to the citrate synthase family
HG566_RS00140	COG0538	isocitrate dehydrogenase activity
HG566_RS00160	COG0589	response to stress
HG566_RS00165	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
HG566_RS00220	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HG566_RS00235	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
HG566_RS00240	COG2957	Belongs to the agmatine deiminase family
HG566_RS00260	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HG566_RS00265	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HG566_RS00265	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HG566_RS00265	COG0506	proline dehydrogenase activity
HG566_RS00315	COG1674	ftsk spoiiie
HG566_RS00330	COG0830	nickel cation binding
HG566_RS00345	COG0804	urea catabolic process
HG566_RS00350	COG0832	Belongs to the urease beta subunit family
HG566_RS00350	COG0831	urea catabolic process
HG566_RS00370	COG0268	Binds directly to 16S ribosomal RNA
HG566_RS00375	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HG566_RS00395	COG0840	transmembrane signaling receptor activity
HG566_RS00425	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HG566_RS00430	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HG566_RS00435	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HG566_RS00470	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HG566_RS00480	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HG566_RS00510	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HG566_RS00525	COG0840	transmembrane signaling receptor activity
HG566_RS00530	COG0737	Belongs to the 5'-nucleotidase family
HG566_RS00540	COG0626	cystathionine gamma-synthase activity
HG566_RS00545	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HG566_RS00565	COG1420	regulation of RNA biosynthetic process
HG566_RS00585	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HG566_RS00590	COG0551	DNA topoisomerase type I activity
HG566_RS00590	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HG566_RS00595	COG0731	radical SAM domain protein
HG566_RS00605	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HG566_RS00605	COG0574	Belongs to the PEP-utilizing enzyme family
HG566_RS00615	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HG566_RS00645	COG1760	l-serine dehydratase
HG566_RS00650	COG0814	amino acid
HG566_RS00655	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
HG566_RS00660	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HG566_RS00670	COG1139	Iron-sulfur cluster binding protein
HG566_RS00675	COG0247	lactate metabolic process
HG566_RS00680	COG1620	l-lactate permease
HG566_RS00685	COG1620	l-lactate permease
HG566_RS00690	COG1194	a g-specific adenine glycosylase
HG566_RS00695	COG0471	metal ion transport
HG566_RS00700	COG3278	Belongs to the heme-copper respiratory oxidase family
HG566_RS00780	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HG566_RS00790	COG0113	porphobilinogen synthase activity
HG566_RS00795	COG0642	Histidine kinase
HG566_RS00800	COG0745	RESPONSE REGULATOR receiver
HG566_RS00815	COG0826	peptidase U32
HG566_RS00830	COG0303	'Molybdopterin
HG566_RS00845	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HG566_RS00850	COG0191	fructose-bisphosphate aldolase activity
HG566_RS00860	COG2089	acid synthase
HG566_RS00865	COG1136	(ABC) transporter
HG566_RS00870	COG0815	Transfers the fatty acyl group on membrane lipoproteins
HG566_RS00915	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HG566_RS00920	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HG566_RS00925	COG1053	succinate dehydrogenase
HG566_RS00940	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HG566_RS00945	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HG566_RS00995	COG0489	protein tyrosine kinase activity
HG566_RS01010	COG0326	Molecular chaperone. Has ATPase activity
HG566_RS01015	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HG566_RS01030	COG0471	metal ion transport
HG566_RS01035	COG0575	Belongs to the CDS family
HG566_RS01055	COG1881	PFAM PEBP family protein
HG566_RS01065	COG1104	cysteine desulfurase activity
HG566_RS01080	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HG566_RS01085	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HG566_RS01085	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HG566_RS01095	COG0730	response to heat
HG566_RS01105	COG0659	secondary active sulfate transmembrane transporter activity
HG566_RS01135	COG0754	glutathionylspermidine amidase activity
HG566_RS01145	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HG566_RS01185	COG0783	Belongs to the Dps family
HG566_RS01190	COG0642	Histidine kinase
HG566_RS01195	COG3951	Flagellar rod assembly protein muramidase FlgJ
HG566_RS01225	COG4239	(ABC) transporter, permease
HG566_RS01260	COG0750	zinc metalloprotease
HG566_RS01280	COG0542	response to heat
HG566_RS01285	COG0785	Cytochrome C biogenesis protein
HG566_RS01290	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HG566_RS01295	COG0402	S-adenosylhomocysteine deaminase activity
HG566_RS01330	COG0727	PFAM Uncharacterised protein family (UPF0153)
HG566_RS01340	COG0134	indole-3-glycerol-phosphate synthase activity
HG566_RS01350	COG0248	Ppx GppA phosphatase
HG566_RS01355	COG0859	PFAM glycosyl transferase family 9
HG566_RS01365	COG0343	queuine tRNA-ribosyltransferase activity
HG566_RS01385	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HG566_RS01390	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HG566_RS01410	COG0019	diaminopimelate decarboxylase activity
HG566_RS01425	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HG566_RS01450	COG0747	negative chemotaxis
HG566_RS01455	COG0601	transmembrane transport
HG566_RS01460	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HG566_RS01465	COG0444	Belongs to the ABC transporter superfamily
HG566_RS01470	COG4608	Belongs to the ABC transporter superfamily
HG566_RS01490	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HG566_RS01505	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HG566_RS01510	COG0726	polysaccharide deacetylase
HG566_RS01520	COG0523	cobalamin synthesis protein
HG566_RS01535	COG0748	coenzyme F420 binding
HG566_RS01570	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
HG566_RS01575	COG3980	spore coat polysaccharide biosynthesis protein
HG566_RS01580	COG3980	spore coat polysaccharide biosynthesis protein
HG566_RS01585	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HG566_RS01590	COG1663	tetraacyldisaccharide 4'-kinase activity
HG566_RS01610	COG2894	cell division
HG566_RS01615	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
HG566_RS01620	COG0758	DNA mediated transformation
HG566_RS01620	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HG566_RS01625	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HG566_RS01630	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HG566_RS01665	COG0564	pseudouridine synthase activity
HG566_RS01670	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
HG566_RS01670	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HG566_RS01675	COG0504	CTP synthase activity
HG566_RS01685	COG1766	The M ring may be actively involved in energy transduction
HG566_RS01690	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HG566_RS01700	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HG566_RS01720	COG4786	Flagellar basal body rod
HG566_RS01725	COG0477	Major facilitator Superfamily
HG566_RS01730	COG1674	ftsk spoiiie
HG566_RS01740	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HG566_RS01745	COG0196	riboflavin kinase activity
HG566_RS01750	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
HG566_RS01770	COG1132	(ABC) transporter
HG566_RS01785	COG1106	Psort location Cytoplasmic, score
HG566_RS01795	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
HG566_RS01815	COG2608	mercury ion transmembrane transporter activity
HG566_RS01825	COG1183	phosphatidylcholine synthase activity
HG566_RS01835	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HG566_RS01845	COG0745	RESPONSE REGULATOR receiver
HG566_RS01870	COG0357	Ribosomal RNA small subunit methyltransferase G
HG566_RS01880	COG0805	protein transport
HG566_RS01935	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
HG566_RS01945	COG0083	homoserine kinase activity
HG566_RS01975	COG1408	metallophosphoesterase
HG566_RS01980	COG0745	RESPONSE REGULATOR receiver
HG566_RS01985	COG2404	hydrolase activity, acting on ester bonds
HG566_RS01990	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HG566_RS02010	COG0006	proline dipeptidase activity
HG566_RS02015	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HG566_RS02020	COG1419	protein localization to endoplasmic reticulum
HG566_RS02025	COG0455	bacterial-type flagellum organization
HG566_RS02040	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HG566_RS02045	COG1776	CheC inhibitor of MCP methylation
HG566_RS02045	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HG566_RS02060	COG0735	belongs to the Fur family
HG566_RS02065	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HG566_RS02065	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HG566_RS02070	COG0789	Transcriptional regulator
HG566_RS02075	COG0484	heat shock protein binding
HG566_RS02090	COG0745	RESPONSE REGULATOR receiver
HG566_RS02105	COG0833	amino acid
HG566_RS02110	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HG566_RS02120	COG1028	Short-chain dehydrogenase reductase Sdr
HG566_RS02140	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HG566_RS02160	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HG566_RS02165	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HG566_RS02245	COG1217	gtp-binding protein TYPA
HG566_RS02325	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HG566_RS02335	COG0824	Thioesterase
HG566_RS02340	COG0733	neurotransmitter:sodium symporter activity
HG566_RS02345	COG0733	neurotransmitter:sodium symporter activity
HG566_RS02355	COG0592	DNA-directed DNA polymerase activity
HG566_RS02360	COG0187	DNA topoisomerase II activity
HG566_RS02375	COG1196	nuclear chromosome segregation
HG566_RS02375	COG0739	heme binding
HG566_RS02375	COG0741	lytic transglycosylase activity
HG566_RS02390	COG0277	FAD linked oxidase domain protein
HG566_RS02405	COG0174	glutamine synthetase
HG566_RS02410	COG3586	endonuclease activity
HG566_RS02560	COG3451	type IV secretory pathway VirB4
HG566_RS02580	COG1842	Phage shock protein A
HG566_RS02590	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HG566_RS02600	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HG566_RS02630	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HG566_RS02670	COG0628	permease
HG566_RS02680	COG0012	GTP binding
HG566_RS02705	COG0698	ribose 5-phosphate isomerase
HG566_RS02710	COG1994	Peptidase M50
HG566_RS02715	COG0681	Belongs to the peptidase S26 family
HG566_RS02755	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HG566_RS02755	COG1776	CheC inhibitor of MCP methylation
HG566_RS02760	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HG566_RS02765	COG1918	ferrous iron import across plasma membrane
HG566_RS02785	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HG566_RS02785	COG0674	pyruvate-flavodoxin oxidoreductase activity
HG566_RS02790	COG1013	pyruvate-flavodoxin oxidoreductase activity
HG566_RS02825	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HG566_RS02830	COG0156	8-amino-7-oxononanoate synthase activity
HG566_RS02835	COG0840	transmembrane signaling receptor activity
HG566_RS02845	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HG566_RS02885	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HG566_RS02895	COG1131	(ABC) transporter
HG566_RS02910	COG0784	Response regulator, receiver
HG566_RS02910	COG0835	chemotaxis
HG566_RS02925	COG3306	glycosyltransferase involved in LPS biosynthesis
HG566_RS02940	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HG566_RS02945	COG1193	negative regulation of DNA recombination
HG566_RS02960	COG0436	Aminotransferase
HG566_RS02970	COG2171	N-acyltransferase activity
HG566_RS02985	COG2249	NAD(P)H dehydrogenase (quinone) activity
HG566_RS02990	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
HG566_RS02995	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
HG566_RS03000	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
HG566_RS03005	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HG566_RS03010	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
HG566_RS03035	COG0617	tRNA 3'-terminal CCA addition
HG566_RS03040	COG0778	Nitroreductase
HG566_RS03045	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HG566_RS03075	COG1027	Aspartate ammonia-lyase
HG566_RS03090	COG0560	Phosphoserine phosphatase
HG566_RS03095	COG1528	Iron-storage protein
HG566_RS03100	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
HG566_RS03105	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HG566_RS03110	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
HG566_RS03120	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HG566_RS03155	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HG566_RS03190	COG4974	Belongs to the 'phage' integrase family
HG566_RS03200	COG0730	response to heat
HG566_RS03210	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HG566_RS03230	COG1338	Plays a role in the flagellum-specific transport system
HG566_RS03240	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
HG566_RS03250	COG0183	Belongs to the thiolase family
HG566_RS03255	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HG566_RS03260	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HG566_RS03265	COG2031	fatty acid transporter
HG566_RS03275	COG0145	ligase activity
HG566_RS03280	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
HG566_RS03285	COG4647	ligase activity
HG566_RS03300	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HG566_RS03305	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HG566_RS03315	COG2204	response regulator
HG566_RS03325	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HG566_RS03360	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HG566_RS03365	COG1137	ATPase activity
HG566_RS03375	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HG566_RS03380	COG1279	arginine transmembrane transporter activity
HG566_RS03395	COG0252	asparaginase activity
HG566_RS03400	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HG566_RS03415	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HG566_RS03420	COG0037	tRNA processing
HG566_RS03455	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
HG566_RS03460	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HG566_RS03465	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HG566_RS03490	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HG566_RS03500	COG0772	Belongs to the SEDS family
HG566_RS03505	COG1160	GTP binding
HG566_RS03510	COG0564	pseudouridine synthase activity
HG566_RS03520	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HG566_RS03525	COG1136	(ABC) transporter
HG566_RS03545	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HG566_RS03575	COG2056	Na+-H+ antiporter family
HG566_RS03580	COG0534	Mate efflux family protein
HG566_RS03600	COG0552	protein localization to endoplasmic reticulum
HG566_RS03625	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HG566_RS03635	COG0746	molybdenum cofactor guanylyltransferase activity
HG566_RS03640	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HG566_RS03650	COG0860	N-Acetylmuramoyl-L-alanine amidase
HG566_RS03660	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HG566_RS03670	COG1758	RNA polymerase activity
HG566_RS03675	COG0528	UMP kinase activity
HG566_RS03715	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
HG566_RS03735	COG0732	type I restriction modification DNA specificity domain
HG566_RS03740	COG2217	Heavy metal translocating P-type atpase
HG566_RS03745	COG0606	chelatase, subunit chli
HG566_RS03775	COG0315	cyclic pyranopterin monophosphate synthase activity
HG566_RS03780	COG0521	Mo-molybdopterin cofactor biosynthetic process
HG566_RS03785	COG0314	molybdopterin synthase activity
HG566_RS03805	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HG566_RS03805	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HG566_RS03825	COG0736	holo-[acyl-carrier-protein] synthase activity
HG566_RS03830	COG1580	Controls the rotational direction of flagella during chemotaxis
HG566_RS03850	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HG566_RS03855	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HG566_RS03860	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HG566_RS03865	COG1360	Flagellar Motor Protein
HG566_RS03875	COG1732	Glycine betaine
HG566_RS03880	COG0517	IMP dehydrogenase activity
HG566_RS03880	COG1125	glycine betaine transport
HG566_RS03900	COG0460	homoserine dehydrogenase
HG566_RS03910	COG3118	belongs to the thioredoxin family
HG566_RS03915	COG0492	ferredoxin-NADP+ reductase activity
HG566_RS03925	COG0724	RNA recognition motif
HG566_RS03935	COG0517	IMP dehydrogenase activity
HG566_RS03935	COG0516	GMP reductase activity
HG566_RS03945	COG0237	dephospho-CoA kinase activity
HG566_RS03965	COG0776	regulation of translation
HG566_RS03990	COG1086	Polysaccharide biosynthesis protein
HG566_RS03995	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HG566_RS04015	COG1083	cytidylyl-transferase
HG566_RS04025	COG2089	acid synthase
HG566_RS04055	COG0671	phosphoesterase, PA-phosphatase related
HG566_RS04070	COG0488	(ABC) transporter
HG566_RS04090	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HG566_RS04095	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HG566_RS04140	COG0375	protein maturation
HG566_RS04145	COG1749	Flagellar hook protein flgE
HG566_RS04150	COG2134	cdp-diacylglycerol pyrophosphatase
HG566_RS04155	COG2824	Alkylphosphonate utilization operon protein PhnA
HG566_RS04170	COG0753	catalase activity
HG566_RS04210	COG0728	peptidoglycan biosynthetic process
HG566_RS04225	COG1120	ATPase activity
HG566_RS04230	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HG566_RS04235	COG0300	oxidoreductase activity
HG566_RS04275	COG0409	Hydrogenase expression formation protein
HG566_RS04280	COG0298	carbon dioxide binding
HG566_RS04285	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HG566_RS04295	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HG566_RS04300	COG0280	phosphate acetyltransferase
HG566_RS04310	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
HG566_RS04315	COG1749	Flagellar hook protein flgE
HG566_RS04315	COG1749	Flagellar hook protein flgE
HG566_RS04355	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HG566_RS04360	COG0670	Belongs to the BI1 family
HG566_RS04365	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HG566_RS04380	COG1942	4-Oxalocrotonate Tautomerase
HG566_RS04405	COG0142	geranyltranstransferase activity
HG566_RS04420	COG0720	synthase
HG566_RS04425	COG0602	queuosine metabolic process
HG566_RS04450	COG0765	amino acid transport
HG566_RS04455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HG566_RS04465	COG1115	amino acid carrier protein
HG566_RS04470	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HG566_RS04475	COG0251	oxidation-reduction process
HG566_RS04505	COG1757	Na H antiporter
HG566_RS04525	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HG566_RS04535	COG1058	Belongs to the CinA family
HG566_RS04535	COG1546	Belongs to the CinA family
HG566_RS04560	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HG566_RS04560	COG1519	Transferase
HG566_RS04570	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HG566_RS04590	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HG566_RS04600	COG3309	Virulence-associated protein D
HG566_RS04635	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HG566_RS04640	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HG566_RS04645	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HG566_RS04655	COG0849	cell division
HG566_RS04660	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HG566_RS04675	COG0668	transmembrane transport
HG566_RS04715	COG1166	arginine decarboxylase activity
HG566_RS04745	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HG566_RS04750	COG0668	transmembrane transport
HG566_RS04800	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HG566_RS04805	COG0537	adenosine 5'-monophosphoramidase activity
HG566_RS04815	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HG566_RS04815	COG0072	phenylalanine-tRNA ligase activity
HG566_RS04830	COG1185	polyribonucleotide nucleotidyltransferase activity
HG566_RS04830	COG0539	negative regulation of cytoplasmic translation
HG566_RS04840	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HG566_RS04845	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HG566_RS04850	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HG566_RS04860	COG0784	Response regulator, receiver
HG566_RS04860	COG0835	chemotaxis
HG566_RS04870	COG0835	chemotaxis
HG566_RS04875	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HG566_RS04880	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HG566_RS04890	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HG566_RS04915	COG0501	Belongs to the peptidase M48B family
HG566_RS04920	COG2890	protein-(glutamine-N5) methyltransferase activity
HG566_RS04925	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HG566_RS04935	COG1333	cytochrome c biogenesis protein
HG566_RS04935	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HG566_RS04955	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HG566_RS04970	COG0511	ligase activity, forming carbon-carbon bonds
HG566_RS04975	COG0439	Biotin carboxylase
HG566_RS05005	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HG566_RS05015	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HG566_RS05020	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HG566_RS05055	COG4221	oxidoreductase activity
HG566_RS05060	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HG566_RS05065	COG0800	Aldolase
HG566_RS05070	COG0129	dihydroxy-acid dehydratase activity
HG566_RS05075	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HG566_RS05080	COG0363	glucosamine-6-phosphate deaminase activity
HG566_RS05090	COG1064	alcohol dehydrogenase
HG566_RS05115	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HG566_RS05125	COG0674	pyruvate-flavodoxin oxidoreductase activity
HG566_RS05130	COG1013	pyruvate-flavodoxin oxidoreductase activity
HG566_RS05135	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HG566_RS05160	COG0405	Gamma-glutamyltransferase
HG566_RS05190	COG1047	Peptidyl-prolyl cis-trans
HG566_RS05200	COG2885	chlorophyll binding
HG566_RS05205	COG0823	Involved in the tonB-independent uptake of proteins
HG566_RS05215	COG0848	biopolymer transport protein
HG566_RS05220	COG0811	peptide transport
HG566_RS05230	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HG566_RS05235	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HG566_RS05260	COG1475	DNA binding
HG566_RS05265	COG1192	Involved in chromosome partitioning
HG566_RS05270	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
HG566_RS05270	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
HG566_RS05275	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HG566_RS05305	COG0336	Belongs to the RNA methyltransferase TrmD family
HG566_RS05325	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HG566_RS05330	COG0525	valine-tRNA ligase activity
HG566_RS05340	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HG566_RS05355	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HG566_RS05360	COG2184	nucleotidyltransferase activity
HG566_RS05380	COG0716	FMN binding
HG566_RS05405	COG0166	Belongs to the GPI family
HG566_RS05415	COG1966	Carbon starvation protein
HG566_RS05425	COG0765	amino acid transport
HG566_RS05430	COG1126	abc transporter atp-binding protein
HG566_RS05445	COG0738	Major facilitator superfamily
HG566_RS05450	COG2252	PERMEase
HG566_RS05470	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HG566_RS05480	COG2814	Major facilitator Superfamily
HG566_RS05485	COG0037	tRNA processing
HG566_RS05490	COG0475	glutathione-regulated potassium exporter activity
HG566_RS05490	COG0569	domain protein
HG566_RS05500	COG2814	Major facilitator Superfamily
HG566_RS05515	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HG566_RS05525	COG0859	PFAM glycosyl transferase family 9
HG566_RS05535	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HG566_RS05575	COG0250	Participates in transcription elongation, termination and antitermination
HG566_RS05620	COG1132	(ABC) transporter
HG566_RS05640	COG1045	serine acetyltransferase
HG566_RS05675	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HG566_RS05685	COG0151	Belongs to the GarS family
HG566_RS05690	COG1131	(ABC) transporter
HG566_RS05695	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HG566_RS05720	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HG566_RS05725	COG2863	cytochrome
HG566_RS05735	COG0527	aspartate kinase activity
HG566_RS05750	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HG566_RS05760	COG0697	spore germination
HG566_RS05775	COG0505	Belongs to the CarA family
HG566_RS05790	COG0424	maF-like protein
HG566_RS05815	COG0629	single-stranded DNA binding
HG566_RS05825	COG1466	dna polymerase III delta subunit
HG566_RS05830	COG0557	exoribonuclease II activity
HG566_RS05845	COG4174	ABC transporter (Permease)
HG566_RS05850	COG4166	transmembrane transport
HG566_RS05855	COG0180	Tryptophanyl-tRNA synthetase
HG566_RS05865	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HG566_RS05885	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HG566_RS05890	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HG566_RS05900	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HG566_RS05935	COG0839	Belongs to the complex I subunit 6 family
HG566_RS05945	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HG566_RS05955	COG1007	ATP synthesis coupled electron transport
HG566_RS05985	COG0133	tryptophan synthase activity
HG566_RS05990	COG0135	phosphoribosylanthranilate isomerase activity
HG566_RS05990	COG0134	indole-3-glycerol-phosphate synthase activity
HG566_RS06000	COG0512	Glutamine amidotransferase of anthranilate synthase
HG566_RS06005	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HG566_RS06010	COG0859	PFAM glycosyl transferase family 9
HG566_RS06020	COG2353	YceI-like domain
HG566_RS06025	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HG566_RS06045	COG0202	RNA polymerase activity
HG566_RS06070	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HG566_RS06075	COG0024	Methionine aminopeptidase
HG566_RS06080	COG0201	protein transport
HG566_RS06115	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HG566_RS06175	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HG566_RS06205	COG0114	fumarate hydratase activity
HG566_RS06225	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HG566_RS06230	COG1687	branched-chain amino acid
HG566_RS06235	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HG566_RS06240	COG0484	heat shock protein binding
HG566_RS06270	COG0811	peptide transport
HG566_RS06275	COG0848	biopolymer transport protein
HG566_RS06280	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HG566_RS06295	COG0861	Integral membrane protein TerC family
HG566_RS06300	COG0598	Magnesium transport protein CorA
HG566_RS06305	COG0126	phosphoglycerate kinase activity
HG566_RS06310	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HG566_RS06320	COG0204	Acyl-transferase
HG566_RS06330	COG0793	Belongs to the peptidase S41A family
HG566_RS06365	COG0157	Belongs to the NadC ModD family
HG566_RS06370	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HG566_RS06390	COG0109	protoheme IX farnesyltransferase activity
HG566_RS06400	COG0305	Participates in initiation and elongation during chromosome replication
HG566_RS06405	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HG566_RS06405	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HG566_RS06410	COG0642	Histidine kinase
HG566_RS06415	COG0745	RESPONSE REGULATOR receiver
HG566_RS06425	COG2189	Belongs to the N(4) N(6)-methyltransferase family
HG566_RS06440	COG1077	Cell shape determining protein MreB Mrl
HG566_RS06445	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HG566_RS06455	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HG566_RS06460	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HG566_RS06465	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HG566_RS06470	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HG566_RS06475	COG0287	Prephenate dehydrogenase
HG566_RS06490	COG3421	Type III restriction
HG566_RS06500	COG1295	ribonuclease BN
HG566_RS06535	COG0799	negative regulation of ribosome biogenesis
HG566_RS06540	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HG566_RS06555	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HG566_RS06560	COG1987	bacterial-type flagellum assembly
HG566_RS06565	COG1157	protein secretion by the type III secretion system
HG566_RS06570	COG4962	Type ii secretion system protein e
HG566_RS06580	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HG566_RS06600	COG0517	IMP dehydrogenase activity
HG566_RS06600	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HG566_RS06605	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HG566_RS06620	COG0732	type I restriction modification DNA specificity domain
HG566_RS06625	COG0788	formyltetrahydrofolate deformylase activity
HG566_RS06670	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HG566_RS06675	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HG566_RS06690	COG0811	peptide transport
HG566_RS06695	COG0848	biopolymer transport protein
HG566_RS06715	COG0706	membrane insertase activity
HG566_RS06725	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HG566_RS06755	COG3118	belongs to the thioredoxin family
HG566_RS06760	COG1187	pseudouridine synthase activity
HG566_RS06765	COG0587	DNA-directed DNA polymerase activity
HG566_RS06790	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HG566_RS06795	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HG566_RS06805	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HG566_RS06815	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HG566_RS06815	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HG566_RS06845	COG0163	prenyltransferase activity
HG566_RS06880	COG2226	methyltransferase
HG566_RS06885	COG1981	membrane
HG566_RS06890	COG1739	Uncharacterized protein family UPF0029
HG566_RS06905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HG566_RS06915	COG1253	flavin adenine dinucleotide binding
HG566_RS06920	COG0306	phosphate transporter
HG566_RS06925	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
HG566_RS06935	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HG566_RS06965	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HG566_RS06985	COG2217	Heavy metal translocating P-type atpase
HG566_RS06990	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
HG566_RS07000	COG0786	glutamate:sodium symporter activity
HG566_RS07010	COG0348	domain, Protein
HG566_RS07015	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
HG566_RS07040	COG0195	Participates in both transcription termination and antitermination
HG566_RS07080	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HG566_RS07095	COG0708	Exodeoxyribonuclease III
HG566_RS07125	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HG566_RS07130	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
HG566_RS07140	COG0732	type I restriction modification DNA specificity domain
HG566_RS07165	COG4772	TonB-dependent receptor
HG566_RS07170	COG0010	Belongs to the arginase family
HG566_RS07175	COG0833	amino acid
HG566_RS07180	COG0686	Belongs to the AlaDH PNT family
HG566_RS07200	COG0497	DNA recombination
HG566_RS07225	COG2176	DNA-directed DNA polymerase activity
HG566_RS07230	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HG566_RS07275	COG1074	ATP-dependent DNA helicase activity
HG566_RS07285	COG1862	Preprotein translocase
HG566_RS07290	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HG566_RS07295	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HG566_RS07305	COG0495	leucyl-tRNA aminoacylation
HG566_RS07315	COG0285	dihydrofolate synthase activity
HG566_RS07325	COG0739	heme binding
HG566_RS07335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HG566_RS07340	COG0723	plastoquinol--plastocyanin reductase activity
HG566_RS07360	COG1106	Psort location Cytoplasmic, score
HG566_RS07365	COG0768	penicillin binding
HG566_RS07380	COG1558	bacterial-type flagellum-dependent cell motility
HG566_RS07385	COG1815	bacterial-type flagellum-dependent cell motility
HG566_RS07390	COG0772	Belongs to the SEDS family
HG566_RS07400	COG0450	alkyl hydroperoxide reductase
HG566_RS07410	COG0768	penicillin binding
HG566_RS07435	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HG566_RS07440	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HG566_RS07445	COG1388	LysM domain
HG566_RS07445	COG0741	lytic transglycosylase activity
HG566_RS07450	COG0084	hydrolase, TatD family'
HG566_RS07455	COG0307	riboflavin synthase, alpha
HG566_RS07470	COG2011	ABC-type metal ion transport system permease component
HG566_RS07480	COG0671	phosphoesterase, PA-phosphatase related
HG566_RS07485	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HG566_RS07505	COG4786	Flagellar basal body rod
HG566_RS07520	COG4735	regulation of single-species biofilm formation