locus-tag	class	description
HG564_RS00020	COG0288	reversible hydration of carbon dioxide
HG564_RS00070	COG0358	DNA primase activity
HG564_RS00075	COG0482	sulfurtransferase activity
HG564_RS00110	COG0784	Response regulator, receiver
HG564_RS00110	COG0835	chemotaxis
HG564_RS00120	COG0671	phosphoesterase, PA-phosphatase related
HG564_RS00125	COG2194	sulfuric ester hydrolase activity
HG564_RS00135	COG0372	Belongs to the citrate synthase family
HG564_RS00140	COG0538	isocitrate dehydrogenase activity
HG564_RS00160	COG0589	response to stress
HG564_RS00165	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
HG564_RS00220	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HG564_RS00235	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
HG564_RS00240	COG2957	Belongs to the agmatine deiminase family
HG564_RS00280	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HG564_RS00285	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HG564_RS00285	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HG564_RS00285	COG0506	proline dehydrogenase activity
HG564_RS00325	COG0830	nickel cation binding
HG564_RS00345	COG0831	urea catabolic process
HG564_RS00345	COG0832	Belongs to the urease beta subunit family
HG564_RS00355	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HG564_RS00365	COG0268	Binds directly to 16S ribosomal RNA
HG564_RS00370	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HG564_RS00390	COG0840	transmembrane signaling receptor activity
HG564_RS00420	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HG564_RS00425	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HG564_RS00430	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HG564_RS00465	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HG564_RS00475	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HG564_RS00480	COG0840	transmembrane signaling receptor activity
HG564_RS00485	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HG564_RS00495	COG1216	Glycosyl transferase, family 2
HG564_RS00505	COG0737	Belongs to the 5'-nucleotidase family
HG564_RS00515	COG0626	cystathionine gamma-synthase activity
HG564_RS00520	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HG564_RS00540	COG1420	regulation of RNA biosynthetic process
HG564_RS00560	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HG564_RS00565	COG0551	DNA topoisomerase type I activity
HG564_RS00565	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HG564_RS00570	COG0731	radical SAM domain protein
HG564_RS00585	COG0574	Belongs to the PEP-utilizing enzyme family
HG564_RS00585	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HG564_RS00595	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HG564_RS00630	COG1760	l-serine dehydratase
HG564_RS00635	COG0814	amino acid
HG564_RS00640	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
HG564_RS00645	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HG564_RS00655	COG1139	Iron-sulfur cluster binding protein
HG564_RS00660	COG0247	lactate metabolic process
HG564_RS00665	COG1620	l-lactate permease
HG564_RS00670	COG1620	l-lactate permease
HG564_RS00675	COG1194	a g-specific adenine glycosylase
HG564_RS00680	COG0471	metal ion transport
HG564_RS00685	COG3278	Belongs to the heme-copper respiratory oxidase family
HG564_RS00765	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HG564_RS00775	COG0113	porphobilinogen synthase activity
HG564_RS00780	COG0642	Histidine kinase
HG564_RS00785	COG0745	RESPONSE REGULATOR receiver
HG564_RS00800	COG0826	peptidase U32
HG564_RS00815	COG0303	'Molybdopterin
HG564_RS00830	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HG564_RS00835	COG0191	fructose-bisphosphate aldolase activity
HG564_RS00845	COG2089	acid synthase
HG564_RS00850	COG1136	(ABC) transporter
HG564_RS00855	COG0815	Transfers the fatty acyl group on membrane lipoproteins
HG564_RS00900	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HG564_RS00905	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HG564_RS00910	COG1053	succinate dehydrogenase
HG564_RS00925	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HG564_RS00980	COG0489	protein tyrosine kinase activity
HG564_RS01015	COG3451	type IV secretory pathway VirB4
HG564_RS01020	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HG564_RS01055	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
HG564_RS01080	COG3041	Addiction module toxin RelE StbE family
HG564_RS01105	COG1192	Involved in chromosome partitioning
HG564_RS01140	COG0582	viral genome integration into host DNA
HG564_RS01145	COG0326	Molecular chaperone. Has ATPase activity
HG564_RS01150	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HG564_RS01165	COG0471	metal ion transport
HG564_RS01170	COG0575	Belongs to the CDS family
HG564_RS01190	COG1881	PFAM PEBP family protein
HG564_RS01200	COG1104	cysteine desulfurase activity
HG564_RS01215	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HG564_RS01220	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HG564_RS01220	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HG564_RS01225	COG0730	response to heat
HG564_RS01235	COG0659	secondary active sulfate transmembrane transporter activity
HG564_RS01265	COG0754	glutathionylspermidine amidase activity
HG564_RS01275	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HG564_RS01315	COG0783	Belongs to the Dps family
HG564_RS01320	COG0642	Histidine kinase
HG564_RS01325	COG3951	Flagellar rod assembly protein muramidase FlgJ
HG564_RS01350	COG4172	Belongs to the ABC transporter superfamily
HG564_RS01355	COG4239	(ABC) transporter, permease
HG564_RS01390	COG0750	zinc metalloprotease
HG564_RS01420	COG0542	response to heat
HG564_RS01425	COG0785	Cytochrome C biogenesis protein
HG564_RS01430	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HG564_RS01435	COG0402	S-adenosylhomocysteine deaminase activity
HG564_RS01470	COG0727	PFAM Uncharacterised protein family (UPF0153)
HG564_RS01480	COG0134	indole-3-glycerol-phosphate synthase activity
HG564_RS01490	COG0248	Ppx GppA phosphatase
HG564_RS01495	COG0859	PFAM glycosyl transferase family 9
HG564_RS01525	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HG564_RS01530	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HG564_RS01550	COG0019	diaminopimelate decarboxylase activity
HG564_RS01565	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HG564_RS01590	COG0747	negative chemotaxis
HG564_RS01595	COG0601	transmembrane transport
HG564_RS01600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HG564_RS01605	COG0444	Belongs to the ABC transporter superfamily
HG564_RS01610	COG4608	Belongs to the ABC transporter superfamily
HG564_RS01645	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HG564_RS01650	COG0726	polysaccharide deacetylase
HG564_RS01670	COG0523	cobalamin synthesis protein
HG564_RS01680	COG0748	coenzyme F420 binding
HG564_RS01715	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
HG564_RS01720	COG3980	spore coat polysaccharide biosynthesis protein
HG564_RS01725	COG3980	spore coat polysaccharide biosynthesis protein
HG564_RS01730	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HG564_RS01735	COG1663	tetraacyldisaccharide 4'-kinase activity
HG564_RS01755	COG2894	cell division
HG564_RS01765	COG0758	DNA mediated transformation
HG564_RS01765	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HG564_RS01810	COG0564	pseudouridine synthase activity
HG564_RS01815	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HG564_RS01815	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
HG564_RS01820	COG0504	CTP synthase activity
HG564_RS01830	COG1766	The M ring may be actively involved in energy transduction
HG564_RS01835	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HG564_RS01845	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HG564_RS01865	COG4786	Flagellar basal body rod
HG564_RS01870	COG0477	Major facilitator Superfamily
HG564_RS01875	COG1674	ftsk spoiiie
HG564_RS01885	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HG564_RS01890	COG0196	riboflavin kinase activity
HG564_RS01895	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HG564_RS01915	COG1132	(ABC) transporter
HG564_RS01930	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
HG564_RS01950	COG2608	mercury ion transmembrane transporter activity
HG564_RS01955	COG2217	Heavy metal translocating P-type atpase
HG564_RS01960	COG1183	phosphatidylcholine synthase activity
HG564_RS01970	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HG564_RS01980	COG0745	RESPONSE REGULATOR receiver
HG564_RS02005	COG0357	Ribosomal RNA small subunit methyltransferase G
HG564_RS02015	COG0805	protein transport
HG564_RS02070	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
HG564_RS02080	COG0083	homoserine kinase activity
HG564_RS02110	COG1408	metallophosphoesterase
HG564_RS02115	COG0745	RESPONSE REGULATOR receiver
HG564_RS02120	COG2404	hydrolase activity, acting on ester bonds
HG564_RS02125	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HG564_RS02145	COG0006	proline dipeptidase activity
HG564_RS02150	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HG564_RS02155	COG1419	protein localization to endoplasmic reticulum
HG564_RS02160	COG0455	bacterial-type flagellum organization
HG564_RS02175	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HG564_RS02180	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HG564_RS02180	COG1776	CheC inhibitor of MCP methylation
HG564_RS02195	COG0735	belongs to the Fur family
HG564_RS02200	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HG564_RS02200	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HG564_RS02205	COG0789	Transcriptional regulator
HG564_RS02210	COG0484	heat shock protein binding
HG564_RS02225	COG0745	RESPONSE REGULATOR receiver
HG564_RS02240	COG0833	amino acid
HG564_RS02245	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HG564_RS02255	COG1028	Short-chain dehydrogenase reductase Sdr
HG564_RS02275	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HG564_RS02295	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HG564_RS02300	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HG564_RS02395	COG1217	gtp-binding protein TYPA
HG564_RS02460	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HG564_RS02470	COG0824	Thioesterase
HG564_RS02475	COG0733	neurotransmitter:sodium symporter activity
HG564_RS02480	COG0733	neurotransmitter:sodium symporter activity
HG564_RS02490	COG0592	DNA-directed DNA polymerase activity
HG564_RS02495	COG0187	DNA topoisomerase II activity
HG564_RS02510	COG0739	heme binding
HG564_RS02510	COG0741	lytic transglycosylase activity
HG564_RS02510	COG1196	nuclear chromosome segregation
HG564_RS02525	COG0277	FAD linked oxidase domain protein
HG564_RS02540	COG0174	glutamine synthetase
HG564_RS02695	COG3451	type IV secretory pathway VirB4
HG564_RS02715	COG1842	Phage shock protein A
HG564_RS02730	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HG564_RS02740	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HG564_RS02745	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HG564_RS02770	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HG564_RS02780	COG1028	Short-chain dehydrogenase reductase Sdr
HG564_RS02810	COG0628	permease
HG564_RS02820	COG0012	GTP binding
HG564_RS02845	COG0698	ribose 5-phosphate isomerase
HG564_RS02850	COG1994	Peptidase M50
HG564_RS02855	COG0681	Belongs to the peptidase S26 family
HG564_RS02895	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HG564_RS02895	COG1776	CheC inhibitor of MCP methylation
HG564_RS02900	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HG564_RS02905	COG1918	ferrous iron import across plasma membrane
HG564_RS02925	COG0674	pyruvate-flavodoxin oxidoreductase activity
HG564_RS02925	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HG564_RS02930	COG1013	pyruvate-flavodoxin oxidoreductase activity
HG564_RS02965	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HG564_RS02970	COG0156	8-amino-7-oxononanoate synthase activity
HG564_RS02985	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HG564_RS03025	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HG564_RS03035	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
HG564_RS03050	COG0784	Response regulator, receiver
HG564_RS03050	COG0835	chemotaxis
HG564_RS03065	COG3306	glycosyltransferase involved in LPS biosynthesis
HG564_RS03075	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HG564_RS03080	COG1193	negative regulation of DNA recombination
HG564_RS03095	COG0436	Aminotransferase
HG564_RS03105	COG2171	N-acyltransferase activity
HG564_RS03120	COG2249	NAD(P)H dehydrogenase (quinone) activity
HG564_RS03125	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
HG564_RS03130	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
HG564_RS03135	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
HG564_RS03140	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HG564_RS03145	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
HG564_RS03170	COG0617	tRNA 3'-terminal CCA addition
HG564_RS03175	COG0778	Nitroreductase
HG564_RS03185	COG0762	integral membrane protein
HG564_RS03210	COG1027	Aspartate ammonia-lyase
HG564_RS03225	COG0560	Phosphoserine phosphatase
HG564_RS03230	COG1528	Iron-storage protein
HG564_RS03235	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
HG564_RS03240	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HG564_RS03245	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
HG564_RS03255	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HG564_RS03270	COG0328	RNA-DNA hybrid ribonuclease activity
HG564_RS03290	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HG564_RS03320	COG4974	Belongs to the 'phage' integrase family
HG564_RS03330	COG0730	response to heat
HG564_RS03340	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HG564_RS03355	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HG564_RS03360	COG1338	Plays a role in the flagellum-specific transport system
HG564_RS03400	COG0183	Belongs to the thiolase family
HG564_RS03405	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HG564_RS03410	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HG564_RS03415	COG2031	fatty acid transporter
HG564_RS03425	COG0145	ligase activity
HG564_RS03430	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
HG564_RS03435	COG4647	ligase activity
HG564_RS03445	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HG564_RS03450	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HG564_RS03460	COG2204	response regulator
HG564_RS03470	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HG564_RS03490	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
HG564_RS03510	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HG564_RS03515	COG1137	ATPase activity
HG564_RS03525	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HG564_RS03530	COG1279	arginine transmembrane transporter activity
HG564_RS03550	COG0252	asparaginase activity
HG564_RS03555	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HG564_RS03570	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HG564_RS03575	COG0037	tRNA processing
HG564_RS03605	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
HG564_RS03610	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HG564_RS03615	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HG564_RS03630	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HG564_RS03640	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HG564_RS03650	COG0772	Belongs to the SEDS family
HG564_RS03665	COG0564	pseudouridine synthase activity
HG564_RS03675	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HG564_RS03680	COG1136	(ABC) transporter
HG564_RS03700	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HG564_RS03730	COG2056	Na+-H+ antiporter family
HG564_RS03735	COG0534	Mate efflux family protein
HG564_RS03755	COG0552	protein localization to endoplasmic reticulum
HG564_RS03770	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HG564_RS03780	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HG564_RS03790	COG0860	N-Acetylmuramoyl-L-alanine amidase
HG564_RS03795	COG0126	phosphoglycerate kinase activity
HG564_RS03800	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HG564_RS03805	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HG564_RS03825	COG1049	propionate catabolic process, 2-methylcitrate cycle
HG564_RS03855	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
HG564_RS03880	COG2217	Heavy metal translocating P-type atpase
HG564_RS03885	COG0606	chelatase, subunit chli
HG564_RS03920	COG0521	Mo-molybdopterin cofactor biosynthetic process
HG564_RS03925	COG0314	molybdopterin synthase activity
HG564_RS03945	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HG564_RS03945	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HG564_RS03965	COG0736	holo-[acyl-carrier-protein] synthase activity
HG564_RS03970	COG1580	Controls the rotational direction of flagella during chemotaxis
HG564_RS03990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HG564_RS03995	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HG564_RS04000	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HG564_RS04005	COG1360	Flagellar Motor Protein
HG564_RS04015	COG1732	Glycine betaine
HG564_RS04020	COG1125	glycine betaine transport
HG564_RS04020	COG0517	IMP dehydrogenase activity
HG564_RS04040	COG0460	homoserine dehydrogenase
HG564_RS04050	COG3118	belongs to the thioredoxin family
HG564_RS04055	COG0492	ferredoxin-NADP+ reductase activity
HG564_RS04065	COG0724	RNA recognition motif
HG564_RS04075	COG0517	IMP dehydrogenase activity
HG564_RS04075	COG0516	GMP reductase activity
HG564_RS04085	COG0237	dephospho-CoA kinase activity
HG564_RS04105	COG0776	regulation of translation
HG564_RS04130	COG1086	Polysaccharide biosynthesis protein
HG564_RS04135	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HG564_RS04155	COG1083	cytidylyl-transferase
HG564_RS04165	COG2089	acid synthase
HG564_RS04195	COG0671	phosphoesterase, PA-phosphatase related
HG564_RS04205	COG0488	(ABC) transporter
HG564_RS04225	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HG564_RS04230	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HG564_RS04240	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HG564_RS04275	COG0375	protein maturation
HG564_RS04280	COG1749	Flagellar hook protein flgE
HG564_RS04285	COG2134	cdp-diacylglycerol pyrophosphatase
HG564_RS04290	COG2824	Alkylphosphonate utilization operon protein PhnA
HG564_RS04305	COG0753	catalase activity
HG564_RS04345	COG0728	peptidoglycan biosynthetic process
HG564_RS04360	COG1120	ATPase activity
HG564_RS04365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HG564_RS04370	COG0300	oxidoreductase activity
HG564_RS04375	COG1607	acyl-coa hydrolase
HG564_RS04380	COG3041	Addiction module toxin RelE StbE family
HG564_RS04415	COG0298	carbon dioxide binding
HG564_RS04420	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HG564_RS04430	COG0280	phosphate acetyltransferase
HG564_RS04440	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
HG564_RS04445	COG1749	Flagellar hook protein flgE
HG564_RS04445	COG1749	Flagellar hook protein flgE
HG564_RS04485	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HG564_RS04490	COG0670	Belongs to the BI1 family
HG564_RS04495	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HG564_RS04515	COG1942	4-Oxalocrotonate Tautomerase
HG564_RS04540	COG0142	geranyltranstransferase activity
HG564_RS04555	COG0720	synthase
HG564_RS04560	COG0602	queuosine metabolic process
HG564_RS04590	COG0765	amino acid transport
HG564_RS04595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HG564_RS04605	COG1115	amino acid carrier protein
HG564_RS04610	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HG564_RS04615	COG0251	oxidation-reduction process
HG564_RS04645	COG1757	Na H antiporter
HG564_RS04665	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HG564_RS04675	COG1058	Belongs to the CinA family
HG564_RS04675	COG1546	Belongs to the CinA family
HG564_RS04695	COG0564	pseudouridine synthase activity
HG564_RS04700	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HG564_RS04700	COG1519	Transferase
HG564_RS04710	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HG564_RS04750	COG3309	Virulence-associated protein D
HG564_RS04785	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HG564_RS04795	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HG564_RS04805	COG0849	cell division
HG564_RS04810	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HG564_RS04835	COG0668	transmembrane transport
HG564_RS04845	COG1570	exodeoxyribonuclease VII activity
HG564_RS04915	COG1166	arginine decarboxylase activity
HG564_RS04940	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HG564_RS04940	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HG564_RS04945	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HG564_RS04950	COG0668	transmembrane transport
HG564_RS05000	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HG564_RS05005	COG0537	adenosine 5'-monophosphoramidase activity
HG564_RS05015	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HG564_RS05015	COG0072	phenylalanine-tRNA ligase activity
HG564_RS05030	COG1185	polyribonucleotide nucleotidyltransferase activity
HG564_RS05030	COG0539	negative regulation of cytoplasmic translation
HG564_RS05040	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HG564_RS05045	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HG564_RS05050	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HG564_RS05060	COG0835	chemotaxis
HG564_RS05060	COG0784	Response regulator, receiver
HG564_RS05065	COG0784	Response regulator, receiver
HG564_RS05065	COG0643	Histidine kinase
HG564_RS05065	COG2198	Histidine kinase
HG564_RS05070	COG0835	chemotaxis
HG564_RS05075	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HG564_RS05080	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HG564_RS05090	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HG564_RS05115	COG0501	Belongs to the peptidase M48B family
HG564_RS05120	COG2890	protein-(glutamine-N5) methyltransferase activity
HG564_RS05135	COG1333	cytochrome c biogenesis protein
HG564_RS05135	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HG564_RS05155	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HG564_RS05170	COG0511	ligase activity, forming carbon-carbon bonds
HG564_RS05175	COG0439	Biotin carboxylase
HG564_RS05195	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HG564_RS05205	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HG564_RS05210	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HG564_RS05245	COG4221	oxidoreductase activity
HG564_RS05250	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HG564_RS05255	COG0800	Aldolase
HG564_RS05260	COG0129	dihydroxy-acid dehydratase activity
HG564_RS05265	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HG564_RS05270	COG0363	glucosamine-6-phosphate deaminase activity
HG564_RS05280	COG1064	alcohol dehydrogenase
HG564_RS05305	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HG564_RS05315	COG0674	pyruvate-flavodoxin oxidoreductase activity
HG564_RS05320	COG1013	pyruvate-flavodoxin oxidoreductase activity
HG564_RS05325	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HG564_RS05355	COG0405	Gamma-glutamyltransferase
HG564_RS05385	COG1047	Peptidyl-prolyl cis-trans
HG564_RS05395	COG2885	chlorophyll binding
HG564_RS05400	COG0823	Involved in the tonB-independent uptake of proteins
HG564_RS05410	COG0848	biopolymer transport protein
HG564_RS05415	COG0811	peptide transport
HG564_RS05425	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HG564_RS05455	COG1475	DNA binding
HG564_RS05460	COG1192	Involved in chromosome partitioning
HG564_RS05470	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HG564_RS05520	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HG564_RS05525	COG0525	valine-tRNA ligase activity
HG564_RS05550	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HG564_RS05555	COG2184	nucleotidyltransferase activity
HG564_RS05565	COG0716	FMN binding
HG564_RS05600	COG1966	Carbon starvation protein
HG564_RS05610	COG0765	amino acid transport
HG564_RS05615	COG1126	abc transporter atp-binding protein
HG564_RS05630	COG0738	Major facilitator superfamily
HG564_RS05635	COG2252	PERMEase
HG564_RS05655	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HG564_RS05665	COG2814	Major facilitator Superfamily
HG564_RS05670	COG0037	tRNA processing
HG564_RS05675	COG0569	domain protein
HG564_RS05675	COG0475	glutathione-regulated potassium exporter activity
HG564_RS05680	COG0534	Mate efflux family protein
HG564_RS05700	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HG564_RS05710	COG0859	PFAM glycosyl transferase family 9
HG564_RS05760	COG0250	Participates in transcription elongation, termination and antitermination
HG564_RS05805	COG1132	(ABC) transporter
HG564_RS05825	COG1045	serine acetyltransferase
HG564_RS05855	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HG564_RS05865	COG0151	Belongs to the GarS family
HG564_RS05870	COG1131	(ABC) transporter
HG564_RS05875	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HG564_RS05900	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HG564_RS05905	COG2863	cytochrome
HG564_RS05915	COG0527	aspartate kinase activity
HG564_RS05930	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HG564_RS05940	COG0697	spore germination
HG564_RS05955	COG0505	Belongs to the CarA family
HG564_RS05995	COG0629	single-stranded DNA binding
HG564_RS06005	COG1466	dna polymerase III delta subunit
HG564_RS06010	COG0557	exoribonuclease II activity
HG564_RS06025	COG4174	ABC transporter (Permease)
HG564_RS06030	COG4166	transmembrane transport
HG564_RS06035	COG0180	Tryptophanyl-tRNA synthetase
HG564_RS06045	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HG564_RS06065	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HG564_RS06070	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HG564_RS06080	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HG564_RS06115	COG0839	Belongs to the complex I subunit 6 family
HG564_RS06125	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HG564_RS06135	COG1007	ATP synthesis coupled electron transport
HG564_RS06160	COG0133	tryptophan synthase activity
HG564_RS06165	COG0135	phosphoribosylanthranilate isomerase activity
HG564_RS06165	COG0134	indole-3-glycerol-phosphate synthase activity
HG564_RS06175	COG0512	Glutamine amidotransferase of anthranilate synthase
HG564_RS06180	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HG564_RS06185	COG0859	PFAM glycosyl transferase family 9
HG564_RS06195	COG2353	YceI-like domain
HG564_RS06200	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HG564_RS06220	COG0202	RNA polymerase activity
HG564_RS06245	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HG564_RS06250	COG0024	Methionine aminopeptidase
HG564_RS06255	COG0201	protein transport
HG564_RS06290	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HG564_RS06310	COG0255	Belongs to the universal ribosomal protein uL29 family
HG564_RS06350	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HG564_RS06380	COG0114	fumarate hydratase activity
HG564_RS06400	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HG564_RS06405	COG1687	branched-chain amino acid
HG564_RS06410	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HG564_RS06415	COG0484	heat shock protein binding
HG564_RS06445	COG0811	peptide transport
HG564_RS06450	COG0848	biopolymer transport protein
HG564_RS06455	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HG564_RS06465	COG0861	Integral membrane protein TerC family
HG564_RS06470	COG0598	Magnesium transport protein CorA
HG564_RS06475	COG0126	phosphoglycerate kinase activity
HG564_RS06480	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HG564_RS06490	COG0204	Acyl-transferase
HG564_RS06500	COG0793	Belongs to the peptidase S41A family
HG564_RS06530	COG0157	Belongs to the NadC ModD family
HG564_RS06535	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HG564_RS06555	COG0109	protoheme IX farnesyltransferase activity
HG564_RS06565	COG0305	Participates in initiation and elongation during chromosome replication
HG564_RS06570	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HG564_RS06570	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HG564_RS06575	COG0642	Histidine kinase
HG564_RS06580	COG0745	RESPONSE REGULATOR receiver
HG564_RS06600	COG2189	Belongs to the N(4) N(6)-methyltransferase family
HG564_RS06605	COG2189	Belongs to the N(4) N(6)-methyltransferase family
HG564_RS06620	COG1077	Cell shape determining protein MreB Mrl
HG564_RS06625	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HG564_RS06645	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HG564_RS06650	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HG564_RS06655	COG0287	Prephenate dehydrogenase
HG564_RS06670	COG3421	Type III restriction
HG564_RS06680	COG1295	ribonuclease BN
HG564_RS06730	COG0799	negative regulation of ribosome biogenesis
HG564_RS06735	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HG564_RS06755	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HG564_RS06760	COG1987	bacterial-type flagellum assembly
HG564_RS06765	COG1157	protein secretion by the type III secretion system
HG564_RS06770	COG4962	Type ii secretion system protein e
HG564_RS06780	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HG564_RS06800	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HG564_RS06800	COG0517	IMP dehydrogenase activity
HG564_RS06805	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HG564_RS06830	COG0788	formyltetrahydrofolate deformylase activity
HG564_RS06835	COG0616	signal peptide processing
HG564_RS06875	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HG564_RS06880	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HG564_RS06895	COG0811	peptide transport
HG564_RS06900	COG0848	biopolymer transport protein
HG564_RS06920	COG0706	membrane insertase activity
HG564_RS06965	COG3118	belongs to the thioredoxin family
HG564_RS06970	COG1187	pseudouridine synthase activity
HG564_RS06975	COG0587	DNA-directed DNA polymerase activity
HG564_RS07000	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HG564_RS07005	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HG564_RS07015	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HG564_RS07025	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HG564_RS07025	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HG564_RS07055	COG0163	prenyltransferase activity
HG564_RS07090	COG2226	methyltransferase
HG564_RS07095	COG1981	membrane
HG564_RS07100	COG1739	Uncharacterized protein family UPF0029
HG564_RS07115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HG564_RS07125	COG1253	flavin adenine dinucleotide binding
HG564_RS07130	COG0306	phosphate transporter
HG564_RS07135	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
HG564_RS07145	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HG564_RS07185	COG2217	Heavy metal translocating P-type atpase
HG564_RS07190	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
HG564_RS07200	COG0786	glutamate:sodium symporter activity
HG564_RS07210	COG0348	domain, Protein
HG564_RS07215	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
HG564_RS07235	COG1921	L-seryl-tRNASec selenium transferase activity
HG564_RS07240	COG0195	Participates in both transcription termination and antitermination
HG564_RS07260	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HG564_RS07275	COG0708	Exodeoxyribonuclease III
HG564_RS07305	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HG564_RS07310	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
HG564_RS07315	COG0732	type I restriction modification DNA specificity domain
HG564_RS07330	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HG564_RS07340	COG4772	TonB-dependent receptor
HG564_RS07345	COG0010	Belongs to the arginase family
HG564_RS07350	COG0686	Belongs to the AlaDH PNT family
HG564_RS07370	COG0497	DNA recombination
HG564_RS07405	COG2176	DNA-directed DNA polymerase activity
HG564_RS07410	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HG564_RS07460	COG1862	Preprotein translocase
HG564_RS07465	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HG564_RS07470	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HG564_RS07480	COG0495	leucyl-tRNA aminoacylation
HG564_RS07490	COG0285	dihydrofolate synthase activity
HG564_RS07500	COG0739	heme binding
HG564_RS07510	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HG564_RS07515	COG0723	plastoquinol--plastocyanin reductase activity
HG564_RS07535	COG0768	penicillin binding
HG564_RS07550	COG1558	bacterial-type flagellum-dependent cell motility
HG564_RS07555	COG1815	bacterial-type flagellum-dependent cell motility
HG564_RS07560	COG0772	Belongs to the SEDS family
HG564_RS07575	COG0450	alkyl hydroperoxide reductase
HG564_RS07585	COG0768	penicillin binding
HG564_RS07610	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HG564_RS07615	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HG564_RS07620	COG1388	LysM domain
HG564_RS07620	COG0741	lytic transglycosylase activity
HG564_RS07625	COG0084	hydrolase, TatD family'
HG564_RS07630	COG0307	riboflavin synthase, alpha
HG564_RS07645	COG2011	ABC-type metal ion transport system permease component
HG564_RS07655	COG0671	phosphoesterase, PA-phosphatase related
HG564_RS07660	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HG564_RS07680	COG4786	Flagellar basal body rod
HG564_RS07690	COG4735	regulation of single-species biofilm formation