locus-tag	class	description
K751_RS00035	COG0582	viral genome integration into host DNA
K751_RS00040	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
K751_RS00045	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
K751_RS00060	COG1053	succinate dehydrogenase
K751_RS00065	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
K751_RS00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K751_RS00120	COG0815	Transfers the fatty acyl group on membrane lipoproteins
K751_RS00125	COG1136	(ABC) transporter
K751_RS00130	COG2089	acid synthase
K751_RS00140	COG0191	fructose-bisphosphate aldolase activity
K751_RS00145	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
K751_RS00175	COG0826	peptidase U32
K751_RS00190	COG0745	RESPONSE REGULATOR receiver
K751_RS00195	COG0642	Histidine kinase
K751_RS00200	COG0113	porphobilinogen synthase activity
K751_RS00210	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
K751_RS00240	COG0148	phosphopyruvate hydratase activity
K751_RS00290	COG3278	Belongs to the heme-copper respiratory oxidase family
K751_RS00295	COG0471	metal ion transport
K751_RS00300	COG1194	a g-specific adenine glycosylase
K751_RS00305	COG1620	l-lactate permease
K751_RS00310	COG1620	l-lactate permease
K751_RS00315	COG0247	lactate metabolic process
K751_RS00320	COG1139	Iron-sulfur cluster binding protein
K751_RS00330	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
K751_RS00340	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
K751_RS00345	COG0814	amino acid
K751_RS00350	COG1760	l-serine dehydratase
K751_RS00390	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
K751_RS00405	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
K751_RS00405	COG0574	Belongs to the PEP-utilizing enzyme family
K751_RS00420	COG0731	radical SAM domain protein
K751_RS00425	COG0551	DNA topoisomerase type I activity
K751_RS00425	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
K751_RS00430	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K751_RS00450	COG1420	regulation of RNA biosynthetic process
K751_RS00470	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K751_RS00475	COG0626	cystathionine gamma-synthase activity
K751_RS00485	COG0737	Belongs to the 5'-nucleotidase family
K751_RS00505	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
K751_RS00510	COG0840	transmembrane signaling receptor activity
K751_RS00515	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
K751_RS00525	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
K751_RS00560	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
K751_RS00565	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
K751_RS00570	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
K751_RS00600	COG0840	transmembrane signaling receptor activity
K751_RS00625	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
K751_RS00640	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
K751_RS00650	COG0831	urea catabolic process
K751_RS00650	COG0832	Belongs to the urease beta subunit family
K751_RS00670	COG0830	nickel cation binding
K751_RS00740	COG0506	proline dehydrogenase activity
K751_RS00740	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
K751_RS00740	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
K751_RS00745	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K751_RS00775	COG0861	Integral membrane protein TerC family
K751_RS00780	COG0598	Magnesium transport protein CorA
K751_RS00785	COG0126	phosphoglycerate kinase activity
K751_RS00790	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
K751_RS00800	COG0204	Acyl-transferase
K751_RS00810	COG0793	Belongs to the peptidase S41A family
K751_RS00835	COG0157	Belongs to the NadC ModD family
K751_RS00840	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
K751_RS00860	COG0109	protoheme IX farnesyltransferase activity
K751_RS00870	COG0305	Participates in initiation and elongation during chromosome replication
K751_RS00875	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
K751_RS00875	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
K751_RS00880	COG0642	Histidine kinase
K751_RS00885	COG0745	RESPONSE REGULATOR receiver
K751_RS00890	COG1792	Involved in formation and maintenance of cell shape
K751_RS00895	COG1077	Cell shape determining protein MreB Mrl
K751_RS00900	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
K751_RS00905	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
K751_RS00910	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
K751_RS00920	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
K751_RS00925	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
K751_RS00930	COG0287	Prephenate dehydrogenase
K751_RS00950	COG2194	sulfuric ester hydrolase activity
K751_RS00955	COG0671	phosphoesterase, PA-phosphatase related
K751_RS00965	COG0784	Response regulator, receiver
K751_RS00965	COG0835	chemotaxis
K751_RS00995	COG0482	sulfurtransferase activity
K751_RS01000	COG0358	DNA primase activity
K751_RS01005	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
K751_RS01080	COG4735	regulation of single-species biofilm formation
K751_RS01090	COG4786	Flagellar basal body rod
K751_RS01120	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
K751_RS01125	COG0671	phosphoesterase, PA-phosphatase related
K751_RS01135	COG2011	ABC-type metal ion transport system permease component
K751_RS01150	COG0307	riboflavin synthase, alpha
K751_RS01155	COG0084	hydrolase, TatD family'
K751_RS01160	COG1388	LysM domain
K751_RS01160	COG0741	lytic transglycosylase activity
K751_RS01165	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
K751_RS01170	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
K751_RS01195	COG0768	penicillin binding
K751_RS01205	COG0450	alkyl hydroperoxide reductase
K751_RS01215	COG0772	Belongs to the SEDS family
K751_RS01220	COG1815	bacterial-type flagellum-dependent cell motility
K751_RS01225	COG1558	bacterial-type flagellum-dependent cell motility
K751_RS01235	COG0768	penicillin binding
K751_RS01240	COG1106	Psort location Cytoplasmic, score
K751_RS01260	COG0723	plastoquinol--plastocyanin reductase activity
K751_RS01265	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
K751_RS01275	COG0739	heme binding
K751_RS01285	COG0285	dihydrofolate synthase activity
K751_RS01295	COG0495	leucyl-tRNA aminoacylation
K751_RS01305	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K751_RS01310	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K751_RS01315	COG1862	Preprotein translocase
K751_RS01325	COG1074	ATP-dependent DNA helicase activity
K751_RS01370	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
K751_RS01415	COG0497	DNA recombination
K751_RS01435	COG0686	Belongs to the AlaDH PNT family
K751_RS01440	COG0833	amino acid
K751_RS01445	COG0010	Belongs to the arginase family
K751_RS01475	COG3451	type IV secretory pathway VirB4
K751_RS01515	COG4962	Type ii secretion system protein e
K751_RS01535	COG1192	Involved in chromosome partitioning
K751_RS01560	COG3041	Addiction module toxin RelE StbE family
K751_RS01585	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
K751_RS01620	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
K751_RS01625	COG3451	type IV secretory pathway VirB4
K751_RS01675	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K751_RS01700	COG0489	protein tyrosine kinase activity
K751_RS01715	COG0326	Molecular chaperone. Has ATPase activity
K751_RS01720	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
K751_RS01735	COG0471	metal ion transport
K751_RS01740	COG0575	Belongs to the CDS family
K751_RS01760	COG1881	PFAM PEBP family protein
K751_RS01770	COG1104	cysteine desulfurase activity
K751_RS01785	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
K751_RS01790	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K751_RS01790	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K751_RS01795	COG0730	response to heat
K751_RS01805	COG0659	secondary active sulfate transmembrane transporter activity
K751_RS01835	COG0754	glutathionylspermidine amidase activity
K751_RS01845	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
K751_RS01885	COG0783	Belongs to the Dps family
K751_RS01890	COG0642	Histidine kinase
K751_RS01895	COG3951	Flagellar rod assembly protein muramidase FlgJ
K751_RS01920	COG4172	Belongs to the ABC transporter superfamily
K751_RS01925	COG4239	(ABC) transporter, permease
K751_RS01960	COG0750	zinc metalloprotease
K751_RS01985	COG0542	response to heat
K751_RS01990	COG0785	Cytochrome C biogenesis protein
K751_RS01995	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
K751_RS02000	COG0402	S-adenosylhomocysteine deaminase activity
K751_RS02035	COG0727	PFAM Uncharacterised protein family (UPF0153)
K751_RS02045	COG0134	indole-3-glycerol-phosphate synthase activity
K751_RS02055	COG0248	Ppx GppA phosphatase
K751_RS02060	COG0859	PFAM glycosyl transferase family 9
K751_RS02090	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
K751_RS02095	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
K751_RS02115	COG0019	diaminopimelate decarboxylase activity
K751_RS02130	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
K751_RS02155	COG0747	negative chemotaxis
K751_RS02160	COG0601	transmembrane transport
K751_RS02165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K751_RS02170	COG0444	Belongs to the ABC transporter superfamily
K751_RS02175	COG4608	Belongs to the ABC transporter superfamily
K751_RS02210	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
K751_RS02225	COG0523	cobalamin synthesis protein
K751_RS02240	COG0748	coenzyme F420 binding
K751_RS02275	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
K751_RS02280	COG3980	spore coat polysaccharide biosynthesis protein
K751_RS02285	COG3980	spore coat polysaccharide biosynthesis protein
K751_RS02290	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K751_RS02295	COG1663	tetraacyldisaccharide 4'-kinase activity
K751_RS02315	COG2894	cell division
K751_RS02320	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
K751_RS02325	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
K751_RS02325	COG0758	DNA mediated transformation
K751_RS02375	COG0564	pseudouridine synthase activity
K751_RS02380	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
K751_RS02380	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
K751_RS02385	COG0504	CTP synthase activity
K751_RS02395	COG1766	The M ring may be actively involved in energy transduction
K751_RS02400	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K751_RS02410	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
K751_RS02425	COG4786	Flagellar basal body rod
K751_RS02430	COG0477	Major facilitator Superfamily
K751_RS02435	COG1674	ftsk spoiiie
K751_RS02445	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
K751_RS02450	COG0196	riboflavin kinase activity
K751_RS02455	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
K751_RS02475	COG1132	(ABC) transporter
K751_RS02495	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
K751_RS02515	COG2608	mercury ion transmembrane transporter activity
K751_RS02520	COG2217	Heavy metal translocating P-type atpase
K751_RS02525	COG1183	phosphatidylcholine synthase activity
K751_RS02535	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
K751_RS02545	COG0745	RESPONSE REGULATOR receiver
K751_RS02570	COG0357	Ribosomal RNA small subunit methyltransferase G
K751_RS02580	COG0805	protein transport
K751_RS02625	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
K751_RS02635	COG0083	homoserine kinase activity
K751_RS02655	COG0779	Required for maturation of 30S ribosomal subunits
K751_RS02665	COG1408	metallophosphoesterase
K751_RS02670	COG0745	RESPONSE REGULATOR receiver
K751_RS02675	COG2404	hydrolase activity, acting on ester bonds
K751_RS02680	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
K751_RS02700	COG0006	proline dipeptidase activity
K751_RS02705	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
K751_RS02710	COG1419	protein localization to endoplasmic reticulum
K751_RS02715	COG0455	bacterial-type flagellum organization
K751_RS02730	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K751_RS02735	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K751_RS02735	COG1776	CheC inhibitor of MCP methylation
K751_RS02750	COG0735	belongs to the Fur family
K751_RS02755	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
K751_RS02755	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
K751_RS02760	COG0789	Transcriptional regulator
K751_RS02765	COG0484	heat shock protein binding
K751_RS02780	COG0745	RESPONSE REGULATOR receiver
K751_RS02795	COG0833	amino acid
K751_RS02800	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
K751_RS02810	COG1028	Short-chain dehydrogenase reductase Sdr
K751_RS02830	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
K751_RS02940	COG1217	gtp-binding protein TYPA
K751_RS03005	COG0753	catalase activity
K751_RS03020	COG2824	Alkylphosphonate utilization operon protein PhnA
K751_RS03025	COG2134	cdp-diacylglycerol pyrophosphatase
K751_RS03030	COG1749	Flagellar hook protein flgE
K751_RS03035	COG0375	protein maturation
K751_RS03050	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
K751_RS03055	COG0756	dUTP diphosphatase activity
K751_RS03070	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
K751_RS03080	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
K751_RS03085	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K751_RS03105	COG0488	(ABC) transporter
K751_RS03115	COG0671	phosphoesterase, PA-phosphatase related
K751_RS03140	COG0351	phosphomethylpyrimidine kinase
K751_RS03155	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
K751_RS03160	COG1086	Polysaccharide biosynthesis protein
K751_RS03185	COG0776	regulation of translation
K751_RS03205	COG0237	dephospho-CoA kinase activity
K751_RS03215	COG0516	GMP reductase activity
K751_RS03215	COG0517	IMP dehydrogenase activity
K751_RS03225	COG0724	RNA recognition motif
K751_RS03235	COG0492	ferredoxin-NADP+ reductase activity
K751_RS03240	COG3118	belongs to the thioredoxin family
K751_RS03250	COG0460	homoserine dehydrogenase
K751_RS03270	COG0517	IMP dehydrogenase activity
K751_RS03270	COG1125	glycine betaine transport
K751_RS03275	COG1732	Glycine betaine
K751_RS03300	COG2189	Belongs to the N(4) N(6)-methyltransferase family
K751_RS03315	COG1360	Flagellar Motor Protein
K751_RS03320	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
K751_RS03325	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K751_RS03330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K751_RS03350	COG1580	Controls the rotational direction of flagella during chemotaxis
K751_RS03355	COG0736	holo-[acyl-carrier-protein] synthase activity
K751_RS03380	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
K751_RS03380	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
K751_RS03400	COG0314	molybdopterin synthase activity
K751_RS03405	COG0521	Mo-molybdopterin cofactor biosynthetic process
K751_RS03440	COG0606	chelatase, subunit chli
K751_RS03445	COG2217	Heavy metal translocating P-type atpase
K751_RS03470	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
K751_RS03500	COG1049	propionate catabolic process, 2-methylcitrate cycle
K751_RS03515	COG1758	RNA polymerase activity
K751_RS03520	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
K751_RS03525	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
K751_RS03530	COG0126	phosphoglycerate kinase activity
K751_RS03535	COG0860	N-Acetylmuramoyl-L-alanine amidase
K751_RS03545	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
K751_RS03575	COG0552	protein localization to endoplasmic reticulum
K751_RS03595	COG0534	Mate efflux family protein
K751_RS03600	COG2056	Na+-H+ antiporter family
K751_RS03630	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
K751_RS03650	COG2884	Cell division ATP-binding protein ftsE
K751_RS03655	COG0220	tRNA (guanine-N7-)-methyltransferase activity
K751_RS03665	COG0564	pseudouridine synthase activity
K751_RS03670	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
K751_RS03680	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
K751_RS03690	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
K751_RS03705	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
K751_RS03710	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
K751_RS03715	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
K751_RS03745	COG0037	tRNA processing
K751_RS03750	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
K751_RS03765	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
K751_RS03770	COG0252	asparaginase activity
K751_RS03785	COG1279	arginine transmembrane transporter activity
K751_RS03790	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
K751_RS03800	COG1137	ATPase activity
K751_RS03805	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
K751_RS03820	COG0617	tRNA 3'-terminal CCA addition
K751_RS03835	COG0778	Nitroreductase
K751_RS03870	COG1027	Aspartate ammonia-lyase
K751_RS03885	COG0560	Phosphoserine phosphatase
K751_RS03890	COG1528	Iron-storage protein
K751_RS03895	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
K751_RS03900	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
K751_RS03905	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
K751_RS03915	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
K751_RS03930	COG0328	RNA-DNA hybrid ribonuclease activity
K751_RS03935	COG0571	ribonuclease III activity
K751_RS03940	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
K751_RS03950	COG0635	Involved in the biosynthesis of porphyrin-containing compound
K751_RS03985	COG4974	Belongs to the 'phage' integrase family
K751_RS03995	COG0730	response to heat
K751_RS04005	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
K751_RS04030	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
K751_RS04040	COG1338	Plays a role in the flagellum-specific transport system
K751_RS04050	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
K751_RS04060	COG0183	Belongs to the thiolase family
K751_RS04065	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
K751_RS04070	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
K751_RS04075	COG2031	fatty acid transporter
K751_RS04085	COG0145	ligase activity
K751_RS04090	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
K751_RS04095	COG4647	ligase activity
K751_RS04110	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
K751_RS04115	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
K751_RS04125	COG2204	response regulator
K751_RS04130	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
K751_RS04150	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
K751_RS04180	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
K751_RS04185	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
K751_RS04190	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
K751_RS04195	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
K751_RS04200	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
K751_RS04205	COG2249	NAD(P)H dehydrogenase (quinone) activity
K751_RS04220	COG2171	N-acyltransferase activity
K751_RS04230	COG0436	Aminotransferase
K751_RS04245	COG1193	negative regulation of DNA recombination
K751_RS04250	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
K751_RS04265	COG3306	glycosyltransferase involved in LPS biosynthesis
K751_RS04280	COG0784	Response regulator, receiver
K751_RS04280	COG0835	chemotaxis
K751_RS04305	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
K751_RS04345	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K751_RS04355	COG0840	transmembrane signaling receptor activity
K751_RS04360	COG0156	8-amino-7-oxononanoate synthase activity
K751_RS04365	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
K751_RS04395	COG1013	pyruvate-flavodoxin oxidoreductase activity
K751_RS04400	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
K751_RS04400	COG0674	pyruvate-flavodoxin oxidoreductase activity
K751_RS04420	COG1918	ferrous iron import across plasma membrane
K751_RS04425	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
K751_RS04430	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K751_RS04430	COG1776	CheC inhibitor of MCP methylation
K751_RS04470	COG0681	Belongs to the peptidase S26 family
K751_RS04475	COG1994	Peptidase M50
K751_RS04480	COG0698	ribose 5-phosphate isomerase
K751_RS04505	COG0012	GTP binding
K751_RS04515	COG0628	permease
K751_RS04545	COG1028	Short-chain dehydrogenase reductase Sdr
K751_RS04555	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
K751_RS04580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K751_RS04585	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
K751_RS04595	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
K751_RS04605	COG1842	Phage shock protein A
K751_RS04625	COG3451	type IV secretory pathway VirB4
K751_RS04790	COG3586	endonuclease activity
K751_RS04795	COG0174	glutamine synthetase
K751_RS04815	COG0277	FAD linked oxidase domain protein
K751_RS04830	COG0739	heme binding
K751_RS04830	COG0741	lytic transglycosylase activity
K751_RS04830	COG1196	nuclear chromosome segregation
K751_RS04845	COG0187	DNA topoisomerase II activity
K751_RS04850	COG0592	DNA-directed DNA polymerase activity
K751_RS04860	COG0733	neurotransmitter:sodium symporter activity
K751_RS04865	COG0733	neurotransmitter:sodium symporter activity
K751_RS04870	COG0824	Thioesterase
K751_RS04880	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
K751_RS04930	COG0728	peptidoglycan biosynthetic process
K751_RS04950	COG1120	ATPase activity
K751_RS04955	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K751_RS04960	COG0300	oxidoreductase activity
K751_RS04965	COG1607	acyl-coa hydrolase
K751_RS04970	COG3041	Addiction module toxin RelE StbE family
K751_RS05005	COG0409	Hydrogenase expression formation protein
K751_RS05010	COG0298	carbon dioxide binding
K751_RS05015	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
K751_RS05035	COG0280	phosphate acetyltransferase
K751_RS05045	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
K751_RS05050	COG1749	Flagellar hook protein flgE
K751_RS05050	COG1749	Flagellar hook protein flgE
K751_RS05095	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
K751_RS05100	COG0670	Belongs to the BI1 family
K751_RS05105	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
K751_RS05120	COG1942	4-Oxalocrotonate Tautomerase
K751_RS05145	COG0142	geranyltranstransferase activity
K751_RS05160	COG0720	synthase
K751_RS05165	COG0602	queuosine metabolic process
K751_RS05195	COG0765	amino acid transport
K751_RS05200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K751_RS05205	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
K751_RS05210	COG1115	amino acid carrier protein
K751_RS05215	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K751_RS05220	COG0251	oxidation-reduction process
K751_RS05250	COG1757	Na H antiporter
K751_RS05275	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
K751_RS05285	COG1546	Belongs to the CinA family
K751_RS05285	COG1058	Belongs to the CinA family
K751_RS05305	COG0564	pseudouridine synthase activity
K751_RS05310	COG1519	Transferase
K751_RS05310	COG0220	tRNA (guanine-N7-)-methyltransferase activity
K751_RS05320	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
K751_RS05325	COG0752	glycyl-tRNA synthetase alpha subunit
K751_RS05380	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
K751_RS05385	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
K751_RS05390	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K751_RS05400	COG0849	cell division
K751_RS05405	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
K751_RS05415	COG0668	transmembrane transport
K751_RS05460	COG1166	arginine decarboxylase activity
K751_RS05475	COG0500	methyltransferase
K751_RS05485	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K751_RS05485	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K751_RS05490	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
K751_RS05495	COG0668	transmembrane transport
K751_RS05550	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
K751_RS05555	COG0537	adenosine 5'-monophosphoramidase activity
K751_RS05565	COG0072	phenylalanine-tRNA ligase activity
K751_RS05565	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K751_RS05580	COG1185	polyribonucleotide nucleotidyltransferase activity
K751_RS05580	COG0539	negative regulation of cytoplasmic translation
K751_RS05590	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
K751_RS05595	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
K751_RS05600	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
K751_RS05610	COG0784	Response regulator, receiver
K751_RS05610	COG0835	chemotaxis
K751_RS05615	COG2198	Histidine kinase
K751_RS05615	COG0784	Response regulator, receiver
K751_RS05615	COG0643	Histidine kinase
K751_RS05620	COG0835	chemotaxis
K751_RS05625	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
K751_RS05630	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
K751_RS05640	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
K751_RS05665	COG0501	Belongs to the peptidase M48B family
K751_RS05670	COG2890	protein-(glutamine-N5) methyltransferase activity
K751_RS05675	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
K751_RS05685	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
K751_RS05685	COG1333	cytochrome c biogenesis protein
K751_RS05705	COG1385	rRNA (uridine-N3-)-methyltransferase activity
K751_RS05720	COG0511	ligase activity, forming carbon-carbon bonds
K751_RS05725	COG0439	Biotin carboxylase
K751_RS05745	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
K751_RS05755	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
K751_RS05760	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
K751_RS05795	COG4221	oxidoreductase activity
K751_RS05800	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
K751_RS05805	COG0800	Aldolase
K751_RS05810	COG0129	dihydroxy-acid dehydratase activity
K751_RS05815	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
K751_RS05820	COG0363	glucosamine-6-phosphate deaminase activity
K751_RS05830	COG1064	alcohol dehydrogenase
K751_RS05855	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
K751_RS05865	COG0674	pyruvate-flavodoxin oxidoreductase activity
K751_RS05870	COG1013	pyruvate-flavodoxin oxidoreductase activity
K751_RS05875	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
K751_RS05900	COG0405	Gamma-glutamyltransferase
K751_RS05930	COG1047	Peptidyl-prolyl cis-trans
K751_RS05940	COG2885	chlorophyll binding
K751_RS05945	COG0823	Involved in the tonB-independent uptake of proteins
K751_RS05955	COG0848	biopolymer transport protein
K751_RS05960	COG0811	peptide transport
K751_RS06000	COG1475	DNA binding
K751_RS06005	COG1192	Involved in chromosome partitioning
K751_RS06015	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
K751_RS06070	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
K751_RS06075	COG0525	valine-tRNA ligase activity
K751_RS06100	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
K751_RS06105	COG2184	nucleotidyltransferase activity
K751_RS06125	COG0716	FMN binding
K751_RS06140	COG0492	ferredoxin-NADP+ reductase activity
K751_RS06160	COG1966	Carbon starvation protein
K751_RS06170	COG0765	amino acid transport
K751_RS06175	COG1126	abc transporter atp-binding protein
K751_RS06190	COG0738	Major facilitator superfamily
K751_RS06195	COG2252	PERMEase
K751_RS06230	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K751_RS06240	COG2814	Major facilitator Superfamily
K751_RS06245	COG0037	tRNA processing
K751_RS06250	COG0475	glutathione-regulated potassium exporter activity
K751_RS06250	COG0569	domain protein
K751_RS06260	COG2814	Major facilitator Superfamily
K751_RS06275	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
K751_RS06285	COG0859	PFAM glycosyl transferase family 9
K751_RS06335	COG0250	Participates in transcription elongation, termination and antitermination
K751_RS06380	COG1132	(ABC) transporter
K751_RS06400	COG1045	serine acetyltransferase
K751_RS06430	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
K751_RS06440	COG0151	Belongs to the GarS family
K751_RS06450	COG1131	(ABC) transporter
K751_RS06455	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
K751_RS06480	COG0635	Involved in the biosynthesis of porphyrin-containing compound
K751_RS06485	COG2863	cytochrome
K751_RS06495	COG0527	aspartate kinase activity
K751_RS06510	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
K751_RS06520	COG0697	spore germination
K751_RS06535	COG0505	Belongs to the CarA family
K751_RS06550	COG0424	maF-like protein
K751_RS06575	COG0629	single-stranded DNA binding
K751_RS06585	COG1466	dna polymerase III delta subunit
K751_RS06590	COG0557	exoribonuclease II activity
K751_RS06605	COG4174	ABC transporter (Permease)
K751_RS06610	COG4166	transmembrane transport
K751_RS06615	COG0180	Tryptophanyl-tRNA synthetase
K751_RS06625	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
K751_RS06645	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
K751_RS06650	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K751_RS06660	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K751_RS06695	COG0839	Belongs to the complex I subunit 6 family
K751_RS06705	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
K751_RS06715	COG1007	ATP synthesis coupled electron transport
K751_RS06740	COG0133	tryptophan synthase activity
K751_RS06745	COG0134	indole-3-glycerol-phosphate synthase activity
K751_RS06745	COG0135	phosphoribosylanthranilate isomerase activity
K751_RS06755	COG0512	Glutamine amidotransferase of anthranilate synthase
K751_RS06760	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
K751_RS06765	COG0859	PFAM glycosyl transferase family 9
K751_RS06775	COG2353	YceI-like domain
K751_RS06780	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
K751_RS06800	COG0202	RNA polymerase activity
K751_RS06805	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
K751_RS06825	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
K751_RS06830	COG0024	Methionine aminopeptidase
K751_RS06835	COG0201	protein transport
K751_RS06870	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
K751_RS06890	COG0255	Belongs to the universal ribosomal protein uL29 family
K751_RS06905	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
K751_RS06930	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
K751_RS06960	COG0114	fumarate hydratase activity
K751_RS06980	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K751_RS06985	COG1687	branched-chain amino acid
K751_RS06990	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
K751_RS06995	COG0484	heat shock protein binding
K751_RS07005	COG0482	sulfurtransferase activity
K751_RS07025	COG0811	peptide transport
K751_RS07030	COG0848	biopolymer transport protein
K751_RS07035	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
K751_RS07050	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
K751_RS07065	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
K751_RS07115	COG0542	response to heat
K751_RS07120	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
K751_RS07125	COG0589	response to stress
K751_RS07145	COG0538	isocitrate dehydrogenase activity
K751_RS07150	COG0372	Belongs to the citrate synthase family
K751_RS07160	COG2189	Belongs to the N(4) N(6)-methyltransferase family
K751_RS07165	COG3421	Type III restriction
K751_RS07175	COG1295	ribonuclease BN
K751_RS07215	COG0799	negative regulation of ribosome biogenesis
K751_RS07235	COG2194	sulfuric ester hydrolase activity
K751_RS07240	COG0812	UDP-N-acetylmuramate dehydrogenase activity
K751_RS07245	COG1987	bacterial-type flagellum assembly
K751_RS07250	COG1157	protein secretion by the type III secretion system
K751_RS07255	COG4962	Type ii secretion system protein e
K751_RS07265	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
K751_RS07285	COG0517	IMP dehydrogenase activity
K751_RS07285	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
K751_RS07290	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
K751_RS07310	COG0788	formyltetrahydrofolate deformylase activity
K751_RS07355	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
K751_RS07375	COG0811	peptide transport
K751_RS07380	COG0848	biopolymer transport protein
K751_RS07400	COG0706	membrane insertase activity
K751_RS07410	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
K751_RS07445	COG3118	belongs to the thioredoxin family
K751_RS07450	COG1187	pseudouridine synthase activity
K751_RS07455	COG0587	DNA-directed DNA polymerase activity
K751_RS07480	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
K751_RS07485	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
K751_RS07495	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K751_RS07505	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K751_RS07505	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K751_RS07530	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
K751_RS07535	COG0163	prenyltransferase activity
K751_RS07570	COG2226	methyltransferase
K751_RS07575	COG1981	membrane
K751_RS07580	COG1739	Uncharacterized protein family UPF0029
K751_RS07595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K751_RS07605	COG1253	flavin adenine dinucleotide binding
K751_RS07610	COG0306	phosphate transporter
K751_RS07615	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
K751_RS07625	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
K751_RS07680	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
K751_RS07690	COG0786	glutamate:sodium symporter activity
K751_RS07700	COG0348	domain, Protein
K751_RS07705	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
K751_RS07725	COG1921	L-seryl-tRNASec selenium transferase activity
K751_RS07730	COG0195	Participates in both transcription termination and antitermination
K751_RS07760	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
K751_RS07775	COG0708	Exodeoxyribonuclease III
K751_RS07810	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
K751_RS07815	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
K751_RS07820	COG0732	type I restriction modification DNA specificity domain
K751_RS07835	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
K751_RS07850	COG3550	peptidyl-serine autophosphorylation
K751_RS07915	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone