locus-tag	class	description
AA973_RS00015	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AA973_RS00020	COG0288	reversible hydration of carbon dioxide
AA973_RS00070	COG0358	DNA primase activity
AA973_RS00075	COG0482	sulfurtransferase activity
AA973_RS00110	COG0835	chemotaxis
AA973_RS00110	COG0784	Response regulator, receiver
AA973_RS00120	COG0671	phosphoesterase, PA-phosphatase related
AA973_RS00125	COG2194	sulfuric ester hydrolase activity
AA973_RS00135	COG0372	Belongs to the citrate synthase family
AA973_RS00140	COG0538	isocitrate dehydrogenase activity
AA973_RS00170	COG0589	response to stress
AA973_RS00175	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AA973_RS00180	COG0542	response to heat
AA973_RS00225	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AA973_RS00240	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AA973_RS00245	COG2957	Belongs to the agmatine deiminase family
AA973_RS00265	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AA973_RS00335	COG0830	nickel cation binding
AA973_RS00350	COG0804	urea catabolic process
AA973_RS00365	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AA973_RS00435	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AA973_RS00440	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AA973_RS00445	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AA973_RS00480	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AA973_RS00495	COG0840	transmembrane signaling receptor activity
AA973_RS00500	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AA973_RS00510	COG1216	Glycosyl transferase, family 2
AA973_RS00520	COG0737	Belongs to the 5'-nucleotidase family
AA973_RS00530	COG0626	cystathionine gamma-synthase activity
AA973_RS00535	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AA973_RS00555	COG1420	regulation of RNA biosynthetic process
AA973_RS00575	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AA973_RS00580	COG0551	DNA topoisomerase type I activity
AA973_RS00580	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AA973_RS00585	COG0731	radical SAM domain protein
AA973_RS00595	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AA973_RS00595	COG0574	Belongs to the PEP-utilizing enzyme family
AA973_RS00610	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AA973_RS00620	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AA973_RS00645	COG1760	l-serine dehydratase
AA973_RS00650	COG0814	amino acid
AA973_RS00655	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AA973_RS00670	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AA973_RS00680	COG1139	Iron-sulfur cluster binding protein
AA973_RS00685	COG0247	lactate metabolic process
AA973_RS00690	COG1620	l-lactate permease
AA973_RS00695	COG1620	l-lactate permease
AA973_RS00700	COG1194	a g-specific adenine glycosylase
AA973_RS00705	COG0471	metal ion transport
AA973_RS00710	COG3278	Belongs to the heme-copper respiratory oxidase family
AA973_RS00735	COG0443	Heat shock 70 kDa protein
AA973_RS00760	COG0148	phosphopyruvate hydratase activity
AA973_RS00790	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AA973_RS00795	COG0217	transcriptional regulatory protein
AA973_RS00800	COG0113	porphobilinogen synthase activity
AA973_RS00805	COG0642	Histidine kinase
AA973_RS00810	COG0745	RESPONSE REGULATOR receiver
AA973_RS00825	COG0826	peptidase U32
AA973_RS00840	COG0303	'Molybdopterin
AA973_RS00860	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AA973_RS00865	COG0191	fructose-bisphosphate aldolase activity
AA973_RS00875	COG2089	acid synthase
AA973_RS00880	COG1136	(ABC) transporter
AA973_RS00885	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AA973_RS00900	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AA973_RS00920	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AA973_RS00925	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AA973_RS00930	COG1053	succinate dehydrogenase
AA973_RS00940	COG0149	triose-phosphate isomerase activity
AA973_RS00945	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AA973_RS00950	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AA973_RS00980	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AA973_RS01005	COG0489	protein tyrosine kinase activity
AA973_RS01030	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AA973_RS01045	COG0471	metal ion transport
AA973_RS01050	COG0575	Belongs to the CDS family
AA973_RS01070	COG1881	PFAM PEBP family protein
AA973_RS01080	COG1104	cysteine desulfurase activity
AA973_RS01095	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AA973_RS01100	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AA973_RS01100	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AA973_RS01105	COG0730	response to heat
AA973_RS01115	COG0659	secondary active sulfate transmembrane transporter activity
AA973_RS01145	COG0754	glutathionylspermidine amidase activity
AA973_RS01155	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AA973_RS01180	COG0142	geranyltranstransferase activity
AA973_RS01195	COG0783	Belongs to the Dps family
AA973_RS01200	COG0642	Histidine kinase
AA973_RS01205	COG3951	Flagellar rod assembly protein muramidase FlgJ
AA973_RS01230	COG4172	Belongs to the ABC transporter superfamily
AA973_RS01235	COG4239	(ABC) transporter, permease
AA973_RS01270	COG0750	zinc metalloprotease
AA973_RS01295	COG0542	response to heat
AA973_RS01300	COG0785	Cytochrome C biogenesis protein
AA973_RS01305	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AA973_RS01310	COG0402	S-adenosylhomocysteine deaminase activity
AA973_RS01320	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AA973_RS01345	COG0727	PFAM Uncharacterised protein family (UPF0153)
AA973_RS01355	COG0134	indole-3-glycerol-phosphate synthase activity
AA973_RS01365	COG0248	Ppx GppA phosphatase
AA973_RS01370	COG0859	PFAM glycosyl transferase family 9
AA973_RS01400	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AA973_RS01405	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AA973_RS01425	COG0019	diaminopimelate decarboxylase activity
AA973_RS01440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AA973_RS01445	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AA973_RS01465	COG0747	negative chemotaxis
AA973_RS01470	COG0601	transmembrane transport
AA973_RS01475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AA973_RS01480	COG0444	Belongs to the ABC transporter superfamily
AA973_RS01485	COG4608	Belongs to the ABC transporter superfamily
AA973_RS01520	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AA973_RS01525	COG0726	polysaccharide deacetylase
AA973_RS01535	COG0523	cobalamin synthesis protein
AA973_RS01545	COG0748	coenzyme F420 binding
AA973_RS01580	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AA973_RS01585	COG3980	spore coat polysaccharide biosynthesis protein
AA973_RS01590	COG3980	spore coat polysaccharide biosynthesis protein
AA973_RS01595	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AA973_RS01600	COG1663	tetraacyldisaccharide 4'-kinase activity
AA973_RS01620	COG2894	cell division
AA973_RS01625	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AA973_RS01630	COG0758	DNA mediated transformation
AA973_RS01630	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AA973_RS01650	COG0564	pseudouridine synthase activity
AA973_RS01655	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AA973_RS01655	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AA973_RS01660	COG0504	CTP synthase activity
AA973_RS01670	COG1766	The M ring may be actively involved in energy transduction
AA973_RS01675	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AA973_RS01685	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AA973_RS01710	COG4786	Flagellar basal body rod
AA973_RS01715	COG0477	Major facilitator Superfamily
AA973_RS01720	COG1674	ftsk spoiiie
AA973_RS01730	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AA973_RS01735	COG0196	riboflavin kinase activity
AA973_RS01760	COG1132	(ABC) transporter
AA973_RS01775	COG1106	Psort location Cytoplasmic, score
AA973_RS01785	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
AA973_RS01805	COG2608	mercury ion transmembrane transporter activity
AA973_RS01815	COG1183	phosphatidylcholine synthase activity
AA973_RS01825	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AA973_RS01835	COG0745	RESPONSE REGULATOR receiver
AA973_RS01860	COG0357	Ribosomal RNA small subunit methyltransferase G
AA973_RS01870	COG0805	protein transport
AA973_RS01925	COG0083	homoserine kinase activity
AA973_RS01950	COG1408	metallophosphoesterase
AA973_RS01955	COG0745	RESPONSE REGULATOR receiver
AA973_RS01960	COG2404	hydrolase activity, acting on ester bonds
AA973_RS01965	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AA973_RS01985	COG0006	proline dipeptidase activity
AA973_RS01990	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AA973_RS01995	COG1419	protein localization to endoplasmic reticulum
AA973_RS02000	COG0455	bacterial-type flagellum organization
AA973_RS02015	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AA973_RS02020	COG1776	CheC inhibitor of MCP methylation
AA973_RS02020	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AA973_RS02035	COG0735	belongs to the Fur family
AA973_RS02040	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AA973_RS02040	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AA973_RS02045	COG0789	Transcriptional regulator
AA973_RS02050	COG0484	heat shock protein binding
AA973_RS02065	COG0745	RESPONSE REGULATOR receiver
AA973_RS02070	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AA973_RS02070	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AA973_RS02080	COG0833	amino acid
AA973_RS02085	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AA973_RS02095	COG1028	Short-chain dehydrogenase reductase Sdr
AA973_RS02100	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AA973_RS02115	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AA973_RS02135	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AA973_RS02190	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AA973_RS02195	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AA973_RS02215	COG1217	gtp-binding protein TYPA
AA973_RS02285	COG0753	catalase activity
AA973_RS02300	COG2824	Alkylphosphonate utilization operon protein PhnA
AA973_RS02305	COG2134	cdp-diacylglycerol pyrophosphatase
AA973_RS02310	COG1749	Flagellar hook protein flgE
AA973_RS02315	COG0375	protein maturation
AA973_RS02330	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AA973_RS02360	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AA973_RS02365	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AA973_RS02375	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AA973_RS02385	COG0488	(ABC) transporter
AA973_RS02395	COG0671	phosphoesterase, PA-phosphatase related
AA973_RS02415	COG0732	type I restriction modification DNA specificity domain
AA973_RS02430	COG0351	phosphomethylpyrimidine kinase
AA973_RS02435	COG0352	thiamine-phosphate diphosphorylase activity
AA973_RS02445	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AA973_RS02450	COG1086	Polysaccharide biosynthesis protein
AA973_RS02475	COG0776	regulation of translation
AA973_RS02480	COG1160	GTP binding
AA973_RS02495	COG0237	dephospho-CoA kinase activity
AA973_RS02505	COG0517	IMP dehydrogenase activity
AA973_RS02505	COG0516	GMP reductase activity
AA973_RS02515	COG0724	RNA recognition motif
AA973_RS02525	COG0492	ferredoxin-NADP+ reductase activity
AA973_RS02530	COG3118	belongs to the thioredoxin family
AA973_RS02540	COG0460	homoserine dehydrogenase
AA973_RS02545	COG0322	excinuclease ABC activity
AA973_RS02560	COG0517	IMP dehydrogenase activity
AA973_RS02560	COG1125	glycine betaine transport
AA973_RS02565	COG1732	Glycine betaine
AA973_RS02575	COG1360	Flagellar Motor Protein
AA973_RS02580	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AA973_RS02585	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AA973_RS02615	COG1580	Controls the rotational direction of flagella during chemotaxis
AA973_RS02620	COG0736	holo-[acyl-carrier-protein] synthase activity
AA973_RS02640	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AA973_RS02640	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AA973_RS02660	COG0314	molybdopterin synthase activity
AA973_RS02665	COG0521	Mo-molybdopterin cofactor biosynthetic process
AA973_RS02700	COG0606	chelatase, subunit chli
AA973_RS02705	COG2217	Heavy metal translocating P-type atpase
AA973_RS02735	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AA973_RS02765	COG1049	propionate catabolic process, 2-methylcitrate cycle
AA973_RS02775	COG0528	UMP kinase activity
AA973_RS02780	COG1758	RNA polymerase activity
AA973_RS02785	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AA973_RS02790	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AA973_RS02800	COG0860	N-Acetylmuramoyl-L-alanine amidase
AA973_RS02810	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AA973_RS02820	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AA973_RS02845	COG0552	protein localization to endoplasmic reticulum
AA973_RS02865	COG0534	Mate efflux family protein
AA973_RS02870	COG2056	Na+-H+ antiporter family
AA973_RS02900	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AA973_RS02920	COG2884	Cell division ATP-binding protein ftsE
AA973_RS02925	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AA973_RS02935	COG0564	pseudouridine synthase activity
AA973_RS02945	COG0772	Belongs to the SEDS family
AA973_RS02955	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AA973_RS02965	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AA973_RS02975	COG1181	Belongs to the D-alanine--D-alanine ligase family
AA973_RS02980	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AA973_RS02985	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AA973_RS02990	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AA973_RS03020	COG0037	tRNA processing
AA973_RS03025	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AA973_RS03040	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AA973_RS03045	COG0252	asparaginase activity
AA973_RS03060	COG1279	arginine transmembrane transporter activity
AA973_RS03065	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AA973_RS03075	COG1137	ATPase activity
AA973_RS03080	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AA973_RS03095	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
AA973_RS03115	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AA973_RS03125	COG2204	response regulator
AA973_RS03135	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AA973_RS03140	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AA973_RS03155	COG4647	ligase activity
AA973_RS03160	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
AA973_RS03175	COG2031	fatty acid transporter
AA973_RS03180	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AA973_RS03185	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AA973_RS03190	COG0183	Belongs to the thiolase family
AA973_RS03200	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AA973_RS03210	COG1338	Plays a role in the flagellum-specific transport system
AA973_RS03230	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AA973_RS03240	COG0730	response to heat
AA973_RS03245	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AA973_RS03250	COG4974	Belongs to the 'phage' integrase family
AA973_RS03280	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AA973_RS03295	COG0571	ribonuclease III activity
AA973_RS03300	COG0328	RNA-DNA hybrid ribonuclease activity
AA973_RS03315	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AA973_RS03325	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AA973_RS03330	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AA973_RS03335	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AA973_RS03340	COG1528	Iron-storage protein
AA973_RS03345	COG0560	Phosphoserine phosphatase
AA973_RS03355	COG1027	Aspartate ammonia-lyase
AA973_RS03380	COG0762	integral membrane protein
AA973_RS03395	COG0617	tRNA 3'-terminal CCA addition
AA973_RS03420	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AA973_RS03425	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AA973_RS03430	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
AA973_RS03435	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AA973_RS03440	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AA973_RS03445	COG2249	NAD(P)H dehydrogenase (quinone) activity
AA973_RS03460	COG2171	N-acyltransferase activity
AA973_RS03470	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AA973_RS03485	COG1193	negative regulation of DNA recombination
AA973_RS03490	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AA973_RS03505	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AA973_RS03510	COG0835	chemotaxis
AA973_RS03510	COG0784	Response regulator, receiver
AA973_RS03540	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AA973_RS03580	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AA973_RS03585	COG0840	transmembrane signaling receptor activity
AA973_RS03590	COG0156	8-amino-7-oxononanoate synthase activity
AA973_RS03595	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AA973_RS03635	COG1013	pyruvate-flavodoxin oxidoreductase activity
AA973_RS03640	COG0674	pyruvate-flavodoxin oxidoreductase activity
AA973_RS03640	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AA973_RS03660	COG1918	ferrous iron import across plasma membrane
AA973_RS03665	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AA973_RS03670	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AA973_RS03670	COG1776	CheC inhibitor of MCP methylation
AA973_RS03705	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AA973_RS03710	COG0681	Belongs to the peptidase S26 family
AA973_RS03715	COG1994	Peptidase M50
AA973_RS03720	COG0698	ribose 5-phosphate isomerase
AA973_RS03745	COG0012	GTP binding
AA973_RS03755	COG0628	permease
AA973_RS03785	COG1028	Short-chain dehydrogenase reductase Sdr
AA973_RS03795	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AA973_RS03815	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AA973_RS03820	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AA973_RS03830	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AA973_RS03850	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AA973_RS03855	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AA973_RS03860	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AA973_RS03870	COG3586	endonuclease activity
AA973_RS03875	COG0174	glutamine synthetase
AA973_RS03890	COG0277	FAD linked oxidase domain protein
AA973_RS03905	COG0741	lytic transglycosylase activity
AA973_RS03905	COG1196	nuclear chromosome segregation
AA973_RS03905	COG0739	heme binding
AA973_RS03920	COG0187	DNA topoisomerase II activity
AA973_RS03925	COG0592	DNA-directed DNA polymerase activity
AA973_RS03935	COG0733	neurotransmitter:sodium symporter activity
AA973_RS03940	COG0733	neurotransmitter:sodium symporter activity
AA973_RS03945	COG0824	Thioesterase
AA973_RS03955	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AA973_RS03995	COG0632	four-way junction helicase activity
AA973_RS04005	COG0728	peptidoglycan biosynthetic process
AA973_RS04010	COG0215	cysteine-tRNA ligase activity
AA973_RS04020	COG1120	ATPase activity
AA973_RS04025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AA973_RS04030	COG0300	oxidoreductase activity
AA973_RS04035	COG1607	acyl-coa hydrolase
AA973_RS04075	COG0298	carbon dioxide binding
AA973_RS04080	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AA973_RS04095	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AA973_RS04100	COG0280	phosphate acetyltransferase
AA973_RS04110	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AA973_RS04115	COG1749	Flagellar hook protein flgE
AA973_RS04115	COG1749	Flagellar hook protein flgE
AA973_RS04155	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AA973_RS04160	COG0670	Belongs to the BI1 family
AA973_RS04165	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AA973_RS04180	COG1942	4-Oxalocrotonate Tautomerase
AA973_RS04205	COG0142	geranyltranstransferase activity
AA973_RS04220	COG0720	synthase
AA973_RS04225	COG0602	queuosine metabolic process
AA973_RS04240	COG0477	Major facilitator Superfamily
AA973_RS04255	COG0765	amino acid transport
AA973_RS04260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AA973_RS04270	COG1115	amino acid carrier protein
AA973_RS04275	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AA973_RS04280	COG0251	oxidation-reduction process
AA973_RS04305	COG1757	Na H antiporter
AA973_RS04325	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AA973_RS04335	COG1058	Belongs to the CinA family
AA973_RS04335	COG1546	Belongs to the CinA family
AA973_RS04350	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AA973_RS04355	COG0564	pseudouridine synthase activity
AA973_RS04360	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AA973_RS04360	COG1519	Transferase
AA973_RS04370	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AA973_RS04380	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AA973_RS04390	COG1160	GTP binding
AA973_RS04400	COG3309	Virulence-associated protein D
AA973_RS04440	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AA973_RS04455	COG0849	cell division
AA973_RS04460	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AA973_RS04475	COG0668	transmembrane transport
AA973_RS04515	COG1166	arginine decarboxylase activity
AA973_RS04540	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AA973_RS04540	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AA973_RS04545	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AA973_RS04550	COG0668	transmembrane transport
AA973_RS04615	COG0537	adenosine 5'-monophosphoramidase activity
AA973_RS04625	COG0072	phenylalanine-tRNA ligase activity
AA973_RS04625	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AA973_RS04640	COG0539	negative regulation of cytoplasmic translation
AA973_RS04640	COG1185	polyribonucleotide nucleotidyltransferase activity
AA973_RS04650	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AA973_RS04655	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AA973_RS04660	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AA973_RS04670	COG0784	Response regulator, receiver
AA973_RS04670	COG0835	chemotaxis
AA973_RS04675	COG0784	Response regulator, receiver
AA973_RS04675	COG2198	Histidine kinase
AA973_RS04675	COG0643	Histidine kinase
AA973_RS04680	COG0835	chemotaxis
AA973_RS04685	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AA973_RS04690	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AA973_RS04700	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AA973_RS04725	COG0501	Belongs to the peptidase M48B family
AA973_RS04730	COG2890	protein-(glutamine-N5) methyltransferase activity
AA973_RS04735	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AA973_RS04745	COG1333	cytochrome c biogenesis protein
AA973_RS04745	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AA973_RS04765	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AA973_RS04780	COG0511	ligase activity, forming carbon-carbon bonds
AA973_RS04785	COG0439	Biotin carboxylase
AA973_RS04795	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AA973_RS04805	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AA973_RS04810	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AA973_RS04845	COG4221	oxidoreductase activity
AA973_RS04850	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AA973_RS04855	COG0800	Aldolase
AA973_RS04860	COG0129	dihydroxy-acid dehydratase activity
AA973_RS04865	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AA973_RS04870	COG0363	glucosamine-6-phosphate deaminase activity
AA973_RS04880	COG1064	alcohol dehydrogenase
AA973_RS04900	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AA973_RS04910	COG0674	pyruvate-flavodoxin oxidoreductase activity
AA973_RS04915	COG1013	pyruvate-flavodoxin oxidoreductase activity
AA973_RS04920	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AA973_RS04955	COG0405	Gamma-glutamyltransferase
AA973_RS04985	COG1047	Peptidyl-prolyl cis-trans
AA973_RS04995	COG2885	chlorophyll binding
AA973_RS05000	COG0823	Involved in the tonB-independent uptake of proteins
AA973_RS05010	COG0848	biopolymer transport protein
AA973_RS05015	COG0811	peptide transport
AA973_RS05055	COG1475	DNA binding
AA973_RS05060	COG1192	Involved in chromosome partitioning
AA973_RS05065	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AA973_RS05065	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AA973_RS05095	COG0336	Belongs to the RNA methyltransferase TrmD family
AA973_RS05115	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AA973_RS05120	COG0525	valine-tRNA ligase activity
AA973_RS05145	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AA973_RS05150	COG2184	nucleotidyltransferase activity
AA973_RS05170	COG0716	FMN binding
AA973_RS05185	COG0492	ferredoxin-NADP+ reductase activity
AA973_RS05205	COG1966	Carbon starvation protein
AA973_RS05220	COG1126	abc transporter atp-binding protein
AA973_RS05235	COG0738	Major facilitator superfamily
AA973_RS05240	COG2252	PERMEase
AA973_RS05260	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AA973_RS05270	COG2814	Major facilitator Superfamily
AA973_RS05275	COG0037	tRNA processing
AA973_RS05280	COG0475	glutathione-regulated potassium exporter activity
AA973_RS05280	COG0569	domain protein
AA973_RS05290	COG2814	Major facilitator Superfamily
AA973_RS05305	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AA973_RS05310	COG0124	histidyl-tRNA synthetase
AA973_RS05315	COG0859	PFAM glycosyl transferase family 9
AA973_RS05320	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AA973_RS05335	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AA973_RS05335	COG0085	RNA polymerase activity
AA973_RS05360	COG0250	Participates in transcription elongation, termination and antitermination
AA973_RS05405	COG1132	(ABC) transporter
AA973_RS05425	COG1045	serine acetyltransferase
AA973_RS05440	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AA973_RS05455	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AA973_RS05465	COG0151	Belongs to the GarS family
AA973_RS05475	COG1131	(ABC) transporter
AA973_RS05480	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AA973_RS05505	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AA973_RS05510	COG2863	cytochrome
AA973_RS05520	COG0527	aspartate kinase activity
AA973_RS05535	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AA973_RS05545	COG0697	spore germination
AA973_RS05560	COG0505	Belongs to the CarA family
AA973_RS05575	COG0424	maF-like protein
AA973_RS05600	COG0629	single-stranded DNA binding
AA973_RS05610	COG1466	dna polymerase III delta subunit
AA973_RS05615	COG0557	exoribonuclease II activity
AA973_RS05620	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AA973_RS05630	COG4174	ABC transporter (Permease)
AA973_RS05635	COG4166	transmembrane transport
AA973_RS05640	COG0180	Tryptophanyl-tRNA synthetase
AA973_RS05650	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AA973_RS05670	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AA973_RS05675	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AA973_RS05685	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AA973_RS05720	COG0839	Belongs to the complex I subunit 6 family
AA973_RS05730	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AA973_RS05740	COG1007	ATP synthesis coupled electron transport
AA973_RS05760	COG0133	tryptophan synthase activity
AA973_RS05765	COG0134	indole-3-glycerol-phosphate synthase activity
AA973_RS05765	COG0135	phosphoribosylanthranilate isomerase activity
AA973_RS05770	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AA973_RS05775	COG0512	Glutamine amidotransferase of anthranilate synthase
AA973_RS05780	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AA973_RS05785	COG0859	PFAM glycosyl transferase family 9
AA973_RS05800	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AA973_RS05820	COG0202	RNA polymerase activity
AA973_RS05845	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AA973_RS05850	COG0024	Methionine aminopeptidase
AA973_RS05855	COG0201	protein transport
AA973_RS05890	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AA973_RS05910	COG0255	Belongs to the universal ribosomal protein uL29 family
AA973_RS05930	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AA973_RS05945	COG0088	Forms part of the polypeptide exit tunnel
AA973_RS05950	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AA973_RS05980	COG0114	fumarate hydratase activity
AA973_RS05995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AA973_RS06000	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AA973_RS06005	COG1687	branched-chain amino acid
AA973_RS06010	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AA973_RS06015	COG0484	heat shock protein binding
AA973_RS06035	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AA973_RS06040	COG0864	Transcriptional regulator
AA973_RS06045	COG0811	peptide transport
AA973_RS06050	COG0848	biopolymer transport protein
AA973_RS06055	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AA973_RS06060	COG0861	Integral membrane protein TerC family
AA973_RS06065	COG0598	Magnesium transport protein CorA
AA973_RS06070	COG0126	phosphoglycerate kinase activity
AA973_RS06075	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AA973_RS06080	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AA973_RS06085	COG0204	Acyl-transferase
AA973_RS06095	COG0793	Belongs to the peptidase S41A family
AA973_RS06115	COG0157	Belongs to the NadC ModD family
AA973_RS06120	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AA973_RS06140	COG0109	protoheme IX farnesyltransferase activity
AA973_RS06150	COG0305	Participates in initiation and elongation during chromosome replication
AA973_RS06155	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AA973_RS06155	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AA973_RS06160	COG0642	Histidine kinase
AA973_RS06165	COG0745	RESPONSE REGULATOR receiver
AA973_RS06190	COG1077	Cell shape determining protein MreB Mrl
AA973_RS06195	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AA973_RS06205	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AA973_RS06215	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
AA973_RS06220	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AA973_RS06225	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AA973_RS06230	COG0287	Prephenate dehydrogenase
AA973_RS06240	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AA973_RS06260	COG1295	ribonuclease BN
AA973_RS06280	COG4786	Flagellar basal body rod
AA973_RS06300	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AA973_RS06305	COG0671	phosphoesterase, PA-phosphatase related
AA973_RS06315	COG2011	ABC-type metal ion transport system permease component
AA973_RS06320	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AA973_RS06330	COG0307	riboflavin synthase, alpha
AA973_RS06335	COG0084	hydrolase, TatD family'
AA973_RS06340	COG1388	LysM domain
AA973_RS06340	COG0741	lytic transglycosylase activity
AA973_RS06345	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AA973_RS06350	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AA973_RS06375	COG0768	penicillin binding
AA973_RS06385	COG0450	alkyl hydroperoxide reductase
AA973_RS06400	COG0772	Belongs to the SEDS family
AA973_RS06405	COG1815	bacterial-type flagellum-dependent cell motility
AA973_RS06410	COG1558	bacterial-type flagellum-dependent cell motility
AA973_RS06420	COG0768	penicillin binding
AA973_RS06435	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AA973_RS06440	COG0723	plastoquinol--plastocyanin reductase activity
AA973_RS06445	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AA973_RS06455	COG0739	heme binding
AA973_RS06465	COG0285	dihydrofolate synthase activity
AA973_RS06475	COG0495	leucyl-tRNA aminoacylation
AA973_RS06485	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AA973_RS06490	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AA973_RS06495	COG1862	Preprotein translocase
AA973_RS06505	COG1074	ATP-dependent DNA helicase activity
AA973_RS06550	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AA973_RS06555	COG2176	DNA-directed DNA polymerase activity
AA973_RS06570	COG0497	DNA recombination
AA973_RS06590	COG0686	Belongs to the AlaDH PNT family
AA973_RS06600	COG4772	TonB-dependent receptor
AA973_RS06610	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AA973_RS06630	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
AA973_RS06635	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AA973_RS06665	COG0708	Exodeoxyribonuclease III
AA973_RS06680	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AA973_RS06705	COG0195	Participates in both transcription termination and antitermination
AA973_RS06710	COG1921	L-seryl-tRNASec selenium transferase activity
AA973_RS06730	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AA973_RS06735	COG0348	domain, Protein
AA973_RS06745	COG0786	glutamate:sodium symporter activity
AA973_RS06755	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AA973_RS06810	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AA973_RS06820	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AA973_RS06825	COG0306	phosphate transporter
AA973_RS06830	COG1253	flavin adenine dinucleotide binding
AA973_RS06840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AA973_RS06855	COG1739	Uncharacterized protein family UPF0029
AA973_RS06860	COG1981	membrane
AA973_RS06865	COG2226	methyltransferase
AA973_RS06900	COG0163	prenyltransferase activity
AA973_RS06910	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AA973_RS06935	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AA973_RS06935	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AA973_RS06945	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AA973_RS06955	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AA973_RS06960	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AA973_RS06985	COG0587	DNA-directed DNA polymerase activity
AA973_RS06990	COG1187	pseudouridine synthase activity
AA973_RS06995	COG3118	belongs to the thioredoxin family
AA973_RS07035	COG0706	membrane insertase activity
AA973_RS07055	COG0848	biopolymer transport protein
AA973_RS07060	COG0811	peptide transport
AA973_RS07070	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AA973_RS07080	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AA973_RS07110	COG0616	signal peptide processing
AA973_RS07115	COG0788	formyltetrahydrofolate deformylase activity
AA973_RS07120	COG0732	type I restriction modification DNA specificity domain
AA973_RS07140	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AA973_RS07140	COG0517	IMP dehydrogenase activity
AA973_RS07160	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AA973_RS07170	COG4962	Type ii secretion system protein e
AA973_RS07175	COG1157	protein secretion by the type III secretion system
AA973_RS07180	COG1987	bacterial-type flagellum assembly
AA973_RS07185	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AA973_RS07215	COG0799	negative regulation of ribosome biogenesis
AA973_RS07220	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AA973_RS07225	COG4735	regulation of single-species biofilm formation