locus-tag	class	description
RC54_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
RC54_RS00120	COG1475	DNA binding
RC54_RS00150	COG5001	Diguanylate cyclase
RC54_RS00150	COG3300	MHYT domain
RC54_RS00175	COG2733	membrane
RC54_RS00180	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RC54_RS00205	COG0840	transmembrane signaling receptor activity
RC54_RS00215	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
RC54_RS00225	COG2814	Major facilitator Superfamily
RC54_RS00230	COG0583	DNA-binding transcription factor activity
RC54_RS00240	COG0840	transmembrane signaling receptor activity
RC54_RS00255	COG0427	acetyl-CoA hydrolase
RC54_RS00260	COG0583	DNA-binding transcription factor activity
RC54_RS00285	COG0505	Belongs to the CarA family
RC54_RS00290	COG0583	DNA-binding transcription factor activity
RC54_RS00325	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
RC54_RS00345	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
RC54_RS00350	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RC54_RS00370	COG3158	transport of potassium into the cell
RC54_RS00385	COG0765	amino acid transport
RC54_RS00415	COG5000	phosphorelay sensor kinase activity
RC54_RS00440	COG1297	OPT oligopeptide transporter protein
RC54_RS00445	COG4589	Belongs to the CDS family
RC54_RS00455	COG0671	phosphoesterase, PA-phosphatase related
RC54_RS00455	COG2453	phosphatase
RC54_RS00460	COG2267	carboxylic ester hydrolase activity
RC54_RS00465	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
RC54_RS00485	COG0347	Belongs to the P(II) protein family
RC54_RS00490	COG0004	ammonium transporteR
RC54_RS00500	COG0189	ligase activity
RC54_RS00510	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
RC54_RS00515	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
RC54_RS00520	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
RC54_RS00530	COG2814	Major facilitator Superfamily
RC54_RS00550	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
RC54_RS00570	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
RC54_RS00575	COG0081	regulation of translation
RC54_RS00585	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
RC54_RS00590	COG0222	ribosome binding
RC54_RS00595	COG0085	RNA polymerase activity
RC54_RS00600	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
RC54_RS00610	COG3720	iron ion transport
RC54_RS00615	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
RC54_RS00620	COG0049	tRNA binding
RC54_RS00625	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
RC54_RS00630	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
RC54_RS00635	COG0051	transcription antitermination factor activity, RNA binding
RC54_RS00640	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
RC54_RS00645	COG0088	Forms part of the polypeptide exit tunnel
RC54_RS00650	COG0089	rRNA binding
RC54_RS00655	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
RC54_RS00660	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
RC54_RS00665	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
RC54_RS00670	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
RC54_RS00675	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
RC54_RS00680	COG0255	Belongs to the universal ribosomal protein uL29 family
RC54_RS00685	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
RC54_RS00690	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
RC54_RS00695	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
RC54_RS00700	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
RC54_RS00705	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
RC54_RS00710	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
RC54_RS00715	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
RC54_RS00720	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
RC54_RS00725	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
RC54_RS00730	COG1841	ribosomal large subunit assembly
RC54_RS00735	COG0200	Binds to the 23S rRNA
RC54_RS00740	COG0201	protein transport
RC54_RS00745	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
RC54_RS00750	COG0257	Belongs to the bacterial ribosomal protein bL36 family
RC54_RS00755	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
RC54_RS00760	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
RC54_RS00765	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
RC54_RS00770	COG0202	RNA polymerase activity
RC54_RS00775	COG0203	ribosomal protein L17
RC54_RS00780	COG1324	tolerance protein
RC54_RS00785	COG4232	protein-disulfide reductase activity
RC54_RS00790	COG0450	alkyl hydroperoxide reductase
RC54_RS00810	COG1012	belongs to the aldehyde dehydrogenase family
RC54_RS00820	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RC54_RS00825	COG1595	DNA-templated transcription, initiation
RC54_RS00835	COG0218	Necessary for normal cell division and for the maintenance of normal septation
RC54_RS00845	COG1333	cytochrome c biogenesis protein
RC54_RS00850	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RC54_RS00855	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RC54_RS00870	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
RC54_RS00880	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
RC54_RS00890	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
RC54_RS00895	COG0588	phosphoglycerate mutase activity
RC54_RS00900	COG4942	peptidase
RC54_RS00905	COG0793	Belongs to the peptidase S41A family
RC54_RS00910	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
RC54_RS00935	COG4977	sequence-specific DNA binding
RC54_RS00935	COG1917	Cupin 2, conserved barrel domain protein
RC54_RS00965	COG0559	Belongs to the binding-protein-dependent transport system permease family
RC54_RS01000	COG3179	chitinase
RC54_RS01010	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
RC54_RS01010	COG0506	proline dehydrogenase activity
RC54_RS01010	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
RC54_RS01015	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
RC54_RS01020	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
RC54_RS01050	COG2165	general secretion pathway protein
RC54_RS01055	COG1965	Belongs to the frataxin family
RC54_RS01080	COG1877	trehalose-phosphatase activity
RC54_RS01085	COG3387	PFAM Glycoside hydrolase 15-related
RC54_RS01090	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
RC54_RS01105	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
RC54_RS01120	COG0494	nUDIX hydrolase
RC54_RS01125	COG3568	Endonuclease Exonuclease Phosphatase
RC54_RS01130	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RC54_RS01135	COG0183	Belongs to the thiolase family
RC54_RS01150	COG0765	amino acid transport
RC54_RS01155	COG0765	amino acid transport
RC54_RS01160	COG1304	FMN binding
RC54_RS01165	COG2186	Transcriptional regulator
RC54_RS01190	COG1960	acyl-CoA dehydrogenase activity
RC54_RS01195	COG1250	3-hydroxyacyl-CoA dehydrogenase
RC54_RS01195	COG1024	Enoyl-CoA hydratase
RC54_RS01200	COG0183	Belongs to the thiolase family
RC54_RS01205	COG1024	Enoyl-CoA hydratase
RC54_RS01210	COG1522	sequence-specific DNA binding
RC54_RS01215	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
RC54_RS01245	COG2199	diguanylate cyclase activity
RC54_RS01260	COG0280	phosphate acetyltransferase
RC54_RS01265	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
RC54_RS01275	COG1309	transcriptional regulator
RC54_RS01280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RC54_RS01285	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RC54_RS01295	COG0395	ABC-type sugar transport system, permease component
RC54_RS01305	COG1653	transport
RC54_RS01335	COG2203	Gaf domain
RC54_RS01335	COG3706	GGDEF domain
RC54_RS01335	COG4251	negative regulation of phosphorylation
RC54_RS01335	COG5001	Diguanylate cyclase
RC54_RS01365	COG0811	peptide transport
RC54_RS01395	COG0443	Heat shock 70 kDa protein
RC54_RS01400	COG0656	L-ascorbic acid biosynthetic process
RC54_RS01410	COG2831	hemolysin activation secretion protein
RC54_RS01430	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
RC54_RS01440	COG0659	secondary active sulfate transmembrane transporter activity
RC54_RS01450	COG1538	Outer membrane efflux protein
RC54_RS01460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RC54_RS01465	COG0657	acetylesterase activity
RC54_RS01475	COG2207	Transcriptional regulator
RC54_RS01480	COG0667	Aldo Keto reductase
RC54_RS01490	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RC54_RS01515	COG2001	Belongs to the MraZ family
RC54_RS01520	COG0275	rRNA processing
RC54_RS01525	COG3116	cell division
RC54_RS01535	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
RC54_RS01540	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
RC54_RS01545	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
RC54_RS01550	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
RC54_RS01560	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
RC54_RS01565	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
RC54_RS01570	COG1181	Belongs to the D-alanine--D-alanine ligase family
RC54_RS01575	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
RC54_RS01585	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
RC54_RS01590	COG0678	peroxiredoxin activity
RC54_RS01595	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
RC54_RS01600	COG0243	molybdopterin cofactor binding
RC54_RS01610	COG0739	heme binding
RC54_RS01610	COG1196	nuclear chromosome segregation
RC54_RS01610	COG0741	lytic transglycosylase activity
RC54_RS01615	COG0653	protein targeting
RC54_RS01625	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
RC54_RS01635	COG0494	nUDIX hydrolase
RC54_RS01640	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
RC54_RS01645	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
RC54_RS01655	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
RC54_RS01660	COG1459	type II secretion system
RC54_RS01670	COG4536	flavin adenine dinucleotide binding
RC54_RS01680	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
RC54_RS01715	COG2755	lipolytic protein G-D-S-L family
RC54_RS01715	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
RC54_RS01725	COG0142	geranyltranstransferase activity
RC54_RS01730	COG0261	This protein binds to 23S rRNA in the presence of protein L20
RC54_RS01735	COG0211	Belongs to the bacterial ribosomal protein bL27 family
RC54_RS01740	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
RC54_RS01745	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
RC54_RS01755	COG0494	nUDIX hydrolase
RC54_RS01760	COG0442	prolyl-tRNA aminoacylation
RC54_RS01775	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
RC54_RS01780	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RC54_RS01785	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RC54_RS01790	COG1116	anion transmembrane transporter activity
RC54_RS01805	COG3023	N-Acetylmuramoyl-L-alanine amidase
RC54_RS01825	COG0762	integral membrane protein
RC54_RS01835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RC54_RS01845	COG2264	protein methyltransferase activity
RC54_RS01850	COG0439	Biotin carboxylase
RC54_RS01855	COG0511	ligase activity, forming carbon-carbon bonds
RC54_RS01860	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
RC54_RS01865	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RC54_RS01880	COG0840	transmembrane signaling receptor activity
RC54_RS01890	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
RC54_RS01895	COG3150	esterase
RC54_RS01900	COG3161	chorismate lyase activity
RC54_RS01905	COG0557	exoribonuclease II activity
RC54_RS01915	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
RC54_RS01920	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RC54_RS01935	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
RC54_RS01950	COG1490	D-aminoacyl-tRNA deacylase activity
RC54_RS01970	COG3550	peptidyl-serine autophosphorylation
RC54_RS01980	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
RC54_RS01985	COG0138	bifunctional purine biosynthesis protein purh
RC54_RS02020	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
RC54_RS02025	COG2354	Protein conserved in bacteria
RC54_RS02030	COG0632	four-way junction helicase activity
RC54_RS02035	COG2255	four-way junction helicase activity
RC54_RS02045	COG1671	Belongs to the UPF0178 family
RC54_RS02055	COG0525	valine-tRNA ligase activity
RC54_RS02060	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
RC54_RS02070	COG2022	thiamine diphosphate biosynthetic process
RC54_RS02075	COG0352	thiamine-phosphate diphosphorylase activity
RC54_RS02075	COG0351	phosphomethylpyrimidine kinase
RC54_RS02075	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
RC54_RS02080	COG0352	thiamine-phosphate diphosphorylase activity
RC54_RS02085	COG0783	Belongs to the Dps family
RC54_RS02100	COG0210	DNA helicase
RC54_RS02105	COG2831	hemolysin activation secretion protein
RC54_RS02115	COG3210	domain, Protein
RC54_RS02115	COG3210	domain, Protein
RC54_RS02155	COG1175	transmembrane transport
RC54_RS02170	COG3842	ATPase activity
RC54_RS02175	COG0246	Mannitol dehydrogenase
RC54_RS02180	COG1070	Carbohydrate kinase
RC54_RS02185	COG0840	transmembrane signaling receptor activity
RC54_RS02195	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
RC54_RS02210	COG1611	Belongs to the LOG family
RC54_RS02220	COG0840	transmembrane signaling receptor activity
RC54_RS02230	COG0412	Dienelactone hydrolase
RC54_RS02250	COG3491	Belongs to the iron ascorbate-dependent oxidoreductase family
RC54_RS02265	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RC54_RS02275	COG1678	Uncharacterized ACR, COG1678
RC54_RS02280	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
RC54_RS02285	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
RC54_RS02290	COG0540	Belongs to the ATCase OTCase family
RC54_RS02305	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
RC54_RS02310	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
RC54_RS02315	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RC54_RS02325	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
RC54_RS02355	COG1215	transferase activity, transferring glycosyl groups
RC54_RS02365	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
RC54_RS02395	COG0463	Glycosyl transferase, family 2
RC54_RS02415	COG1215	transferase activity, transferring glycosyl groups
RC54_RS02420	COG0438	transferase activity, transferring glycosyl groups
RC54_RS02425	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
RC54_RS02495	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RC54_RS02500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RC54_RS02505	COG1309	transcriptional regulator
RC54_RS02510	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
RC54_RS02515	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
RC54_RS02535	COG1968	undecaprenyl-diphosphatase activity
RC54_RS02540	COG1968	undecaprenyl-diphosphatase activity
RC54_RS02545	COG0514	ATP-dependent DNA helicase (RecQ)
RC54_RS02585	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
RC54_RS02595	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
RC54_RS02600	COG1278	Cold shock
RC54_RS02615	COG0518	GMP synthase (glutamine-hydrolyzing) activity
RC54_RS02615	COG0519	Catalyzes the synthesis of GMP from XMP
RC54_RS02625	COG0840	transmembrane signaling receptor activity
RC54_RS02640	COG0500	methyltransferase
RC54_RS02675	COG0583	DNA-binding transcription factor activity
RC54_RS02710	COG1971	Probably functions as a manganese efflux pump
RC54_RS02715	COG0129	dihydroxy-acid dehydratase activity
RC54_RS02720	COG0628	permease
RC54_RS02725	COG0346	lactoylglutathione lyase activity
RC54_RS02735	COG2814	Major facilitator Superfamily
RC54_RS02740	COG0840	transmembrane signaling receptor activity
RC54_RS02785	COG4191	Histidine kinase
RC54_RS02785	COG0784	Response regulator, receiver
RC54_RS02790	COG5001	Diguanylate cyclase
RC54_RS02790	COG3300	MHYT domain
RC54_RS02800	COG3685	Protein conserved in bacteria
RC54_RS02805	COG3546	catalase activity
RC54_RS02825	COG1063	alcohol dehydrogenase
RC54_RS02835	COG2203	Gaf domain
RC54_RS02835	COG2199	diguanylate cyclase activity
RC54_RS02835	COG2200	EAL domain
RC54_RS02850	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
RC54_RS02870	COG0004	ammonium transporteR
RC54_RS02890	COG0583	DNA-binding transcription factor activity
RC54_RS02895	COG3384	dioxygenase
RC54_RS02915	COG1981	membrane
RC54_RS02920	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
RC54_RS02935	COG0495	leucyl-tRNA aminoacylation
RC54_RS02940	COG1609	Transcriptional regulator
RC54_RS02950	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
RC54_RS02955	COG1177	transmembrane transport
RC54_RS02960	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
RC54_RS02965	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
RC54_RS02985	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
RC54_RS02990	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
RC54_RS02995	COG0735	belongs to the Fur family
RC54_RS03000	COG1420	regulation of RNA biosynthetic process
RC54_RS03015	COG0497	DNA recombination
RC54_RS03020	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
RC54_RS03030	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
RC54_RS03035	COG0443	Heat shock 70 kDa protein
RC54_RS03040	COG0484	heat shock protein binding
RC54_RS03045	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
RC54_RS03065	COG1366	Belongs to the anti-sigma-factor antagonist family
RC54_RS03075	COG3290	protein histidine kinase activity
RC54_RS03075	COG0840	transmembrane signaling receptor activity
RC54_RS03080	COG0835	chemotaxis
RC54_RS03090	COG2201	protein-glutamate methylesterase activity
RC54_RS03095	COG4251	negative regulation of phosphorylation
RC54_RS03095	COG2203	Gaf domain
RC54_RS03095	COG3706	GGDEF domain
RC54_RS03095	COG5001	Diguanylate cyclase
RC54_RS03105	COG0617	tRNA 3'-terminal CCA addition
RC54_RS03115	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
RC54_RS03120	COG0628	permease
RC54_RS03140	COG2308	Evidence 4 Homologs of previously reported genes of
RC54_RS03165	COG2308	Evidence 4 Homologs of previously reported genes of
RC54_RS03165	COG2307	Protein conserved in bacteria
RC54_RS03175	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RC54_RS03185	COG0642	Histidine kinase
RC54_RS03205	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RC54_RS03210	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RC54_RS03240	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
RC54_RS03245	COG0861	Integral membrane protein TerC family
RC54_RS03250	COG4969	Belongs to the N-Me-Phe pilin family
RC54_RS03255	COG0315	cyclic pyranopterin monophosphate synthase activity
RC54_RS03260	COG4783	chaperone-mediated protein folding
RC54_RS03290	COG0126	phosphoglycerate kinase activity
RC54_RS03295	COG0469	pyruvate kinase activity
RC54_RS03305	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
RC54_RS03310	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
RC54_RS03315	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
RC54_RS03320	COG0009	L-threonylcarbamoyladenylate synthase
RC54_RS03325	COG3047	cAMP biosynthetic process
RC54_RS03330	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RC54_RS03335	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
RC54_RS03340	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
RC54_RS03345	COG0259	pyridoxamine-phosphate oxidase activity
RC54_RS03355	COG2353	YceI-like domain
RC54_RS03420	COG0482	sulfurtransferase activity
RC54_RS03435	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
RC54_RS03455	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RC54_RS03460	COG0006	proline dipeptidase activity
RC54_RS03475	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
RC54_RS03480	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
RC54_RS03485	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
RC54_RS03490	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
RC54_RS03500	COG5001	Diguanylate cyclase
RC54_RS03535	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
RC54_RS03540	COG0751	glycine-tRNA ligase activity
RC54_RS03545	COG0752	glycyl-tRNA synthetase alpha subunit
RC54_RS03550	COG0815	Transfers the fatty acyl group on membrane lipoproteins
RC54_RS03555	COG4535	Mg2 and Co2 transporter CorC
RC54_RS03560	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
RC54_RS03565	COG1702	phosphate starvation-inducible protein PhoH
RC54_RS03570	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
RC54_RS03580	COG1335	isochorismatase
RC54_RS03585	COG0572	uridine kinase
RC54_RS03590	COG1879	ABC-type sugar transport system periplasmic component
RC54_RS03595	COG1129	ABC transporter
RC54_RS03600	COG1172	Belongs to the binding-protein-dependent transport system permease family
RC54_RS03610	COG5001	Diguanylate cyclase
RC54_RS03610	COG3706	GGDEF domain
RC54_RS03610	COG2203	Gaf domain
RC54_RS03610	COG4251	negative regulation of phosphorylation
RC54_RS03620	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
RC54_RS03625	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
RC54_RS03635	COG2199	diguanylate cyclase activity
RC54_RS03635	COG2202	Pas domain
RC54_RS03635	COG2200	EAL domain
RC54_RS03640	COG0586	Pfam SNARE associated Golgi protein
RC54_RS03645	COG0860	N-Acetylmuramoyl-L-alanine amidase
RC54_RS03650	COG0802	atpase or kinase
RC54_RS03655	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
RC54_RS03665	COG4566	intracellular signal transduction
RC54_RS03695	COG4974	Belongs to the 'phage' integrase family
RC54_RS03700	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
RC54_RS03705	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
RC54_RS03710	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
RC54_RS03715	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
RC54_RS03730	COG0534	Mate efflux family protein
RC54_RS03740	COG0254	rRNA binding
RC54_RS03745	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
RC54_RS03760	COG1074	ATP-dependent DNA helicase activity
RC54_RS03770	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
RC54_RS03775	COG2081	HI0933 family
RC54_RS03780	COG0828	Belongs to the bacterial ribosomal protein bS21 family
RC54_RS03795	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
RC54_RS03805	COG0582	viral genome integration into host DNA
RC54_RS04060	COG0154	amidase activity
RC54_RS04095	COG0583	DNA-binding transcription factor activity
RC54_RS04115	COG3829	transcription factor binding
RC54_RS04125	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RC54_RS04140	COG1172	Belongs to the binding-protein-dependent transport system permease family
RC54_RS04155	COG0410	ABC transporter
RC54_RS04160	COG0471	metal ion transport
RC54_RS04185	COG3842	ATPase activity
RC54_RS04190	COG3842	ATPase activity
RC54_RS04200	COG0395	ABC-type sugar transport system, permease component
RC54_RS04215	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
RC54_RS04230	COG2223	nitrite transmembrane transporter activity
RC54_RS04235	COG2207	Transcriptional regulator
RC54_RS04250	COG1960	acyl-CoA dehydrogenase activity
RC54_RS04255	COG2755	lipolytic protein G-D-S-L family
RC54_RS04255	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
RC54_RS04280	COG4681	YaeQ
RC54_RS04295	COG2951	lytic endotransglycosylase activity
RC54_RS04300	COG0123	including yeast histone deacetylase and acetoin utilization protein
RC54_RS04310	COG0477	Major facilitator Superfamily
RC54_RS04315	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
RC54_RS04325	COG2011	ABC-type metal ion transport system permease component
RC54_RS04330	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
RC54_RS04335	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
RC54_RS04340	COG0459	protein refolding
RC54_RS04345	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
RC54_RS04350	COG2207	Transcriptional regulator
RC54_RS04360	COG1960	acyl-CoA dehydrogenase activity
RC54_RS04405	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RC54_RS04430	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RC54_RS04435	COG3300	MHYT domain
RC54_RS04435	COG5001	Diguanylate cyclase
RC54_RS04440	COG1172	Belongs to the binding-protein-dependent transport system permease family
RC54_RS04445	COG1129	ABC transporter
RC54_RS04455	COG1172	Belongs to the binding-protein-dependent transport system permease family
RC54_RS04465	COG4154	Belongs to the RbsD FucU family
RC54_RS04470	COG1012	belongs to the aldehyde dehydrogenase family
RC54_RS04480	COG1349	DNA-binding transcription factor activity
RC54_RS04485	COG0024	Methionine aminopeptidase
RC54_RS04490	COG0697	spore germination
RC54_RS04495	COG1846	Transcriptional regulator
RC54_RS04500	COG2223	nitrite transmembrane transporter activity
RC54_RS04505	COG4948	Mandelate Racemase Muconate Lactonizing
RC54_RS04510	COG0800	Aldolase
RC54_RS04515	COG3734	2-keto-3-deoxy-galactonokinase
RC54_RS04525	COG1879	ABC-type sugar transport system periplasmic component
RC54_RS04530	COG1129	ABC transporter
RC54_RS04535	COG1172	Belongs to the binding-protein-dependent transport system permease family
RC54_RS04540	COG1172	Belongs to the binding-protein-dependent transport system permease family
RC54_RS04545	COG4213	ABC transporter substrate-binding protein
RC54_RS04555	COG4214	carbohydrate transport
RC54_RS04590	COG4948	Mandelate Racemase Muconate Lactonizing
RC54_RS04595	COG1028	Short-chain dehydrogenase reductase Sdr
RC54_RS04600	COG3254	rhamnose metabolic process
RC54_RS04610	COG1172	Belongs to the binding-protein-dependent transport system permease family
RC54_RS04615	COG1879	ABC-type sugar transport system periplasmic component
RC54_RS04620	COG3618	amidohydrolase
RC54_RS04625	COG1309	transcriptional regulator
RC54_RS04640	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
RC54_RS04650	COG0300	oxidoreductase activity
RC54_RS04670	COG1879	ABC-type sugar transport system periplasmic component
RC54_RS04675	COG1129	ABC transporter
RC54_RS04680	COG1172	Belongs to the binding-protein-dependent transport system permease family
RC54_RS04690	COG1069	ribulokinase activity
RC54_RS04695	COG1028	Short-chain dehydrogenase reductase Sdr
RC54_RS04715	COG0518	GMP synthase (glutamine-hydrolyzing) activity
RC54_RS04715	COG0519	Catalyzes the synthesis of GMP from XMP
RC54_RS04720	COG4774	siderophore transport
RC54_RS04730	COG1595	DNA-templated transcription, initiation
RC54_RS04735	COG0583	DNA-binding transcription factor activity
RC54_RS04745	COG0477	Major facilitator Superfamily
RC54_RS04755	COG1177	transmembrane transport
RC54_RS04760	COG1176	ABC-type spermidine putrescine transport system, permease component I
RC54_RS04770	COG3842	ATPase activity
RC54_RS04775	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
RC54_RS04785	COG0540	Belongs to the ATCase OTCase family
RC54_RS04795	COG1253	flavin adenine dinucleotide binding
RC54_RS04805	COG0405	Gamma-glutamyltransferase
RC54_RS04810	COG1609	Transcriptional regulator
RC54_RS04820	COG1070	Carbohydrate kinase
RC54_RS04825	COG1028	Short-chain dehydrogenase reductase Sdr
RC54_RS04830	COG1063	alcohol dehydrogenase
RC54_RS04835	COG0840	transmembrane signaling receptor activity
RC54_RS04840	COG1063	alcohol dehydrogenase
RC54_RS04845	COG1461	Dihydroxyacetone kinase
RC54_RS04850	COG2376	Dihydroxyacetone kinase
RC54_RS04855	COG1028	Short-chain dehydrogenase reductase Sdr
RC54_RS04860	COG1879	ABC-type sugar transport system periplasmic component
RC54_RS04865	COG1172	Belongs to the binding-protein-dependent transport system permease family
RC54_RS04870	COG1129	ABC transporter
RC54_RS04875	COG0698	ribose 5-phosphate isomerase
RC54_RS04880	COG2390	Transcriptional regulator
RC54_RS04885	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
RC54_RS04890	COG1737	Transcriptional regulator
RC54_RS04895	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
RC54_RS04905	COG0129	dihydroxy-acid dehydratase activity
RC54_RS04910	COG0800	Aldolase
RC54_RS04935	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
RC54_RS04940	COG0583	DNA-binding transcription factor activity
RC54_RS04945	COG4654	Cytochrome c, class I
RC54_RS04955	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RC54_RS04960	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
RC54_RS04975	COG2814	Major facilitator Superfamily
RC54_RS04980	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
RC54_RS05005	COG1522	sequence-specific DNA binding
RC54_RS05010	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RC54_RS05020	COG0454	-acetyltransferase
RC54_RS05025	COG1012	belongs to the aldehyde dehydrogenase family
RC54_RS05030	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RC54_RS05035	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RC54_RS05050	COG0747	negative chemotaxis
RC54_RS05055	COG0601	transmembrane transport
RC54_RS05060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RC54_RS05075	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RC54_RS05080	COG0583	DNA-binding transcription factor activity
RC54_RS05085	COG0251	oxidation-reduction process
RC54_RS05095	COG1473	amidohydrolase
RC54_RS05105	COG0583	DNA-binding transcription factor activity
RC54_RS05115	COG0840	transmembrane signaling receptor activity
RC54_RS05120	COG0280	phosphate acetyltransferase
RC54_RS05120	COG0281	malic enzyme
RC54_RS05140	COG0811	peptide transport
RC54_RS05180	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RC54_RS05190	COG1609	Transcriptional regulator
RC54_RS05220	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
RC54_RS05225	COG1570	exodeoxyribonuclease VII activity
RC54_RS05230	COG0811	peptide transport
RC54_RS05235	COG0848	biopolymer transport protein
RC54_RS05240	COG1663	tetraacyldisaccharide 4'-kinase activity
RC54_RS05245	COG2835	tetraacyldisaccharide 4'-kinase activity
RC54_RS05250	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
RC54_RS05255	COG0563	adenylate kinase activity
RC54_RS05260	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
RC54_RS05280	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
RC54_RS05285	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RC54_RS05285	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
RC54_RS05290	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RC54_RS05295	COG0668	transmembrane transport
RC54_RS05305	COG0267	Belongs to the bacterial ribosomal protein bL33 family
RC54_RS05310	COG0227	Belongs to the bacterial ribosomal protein bL28 family
RC54_RS05315	COG2003	Belongs to the UPF0758 family
RC54_RS05320	COG1047	Peptidyl-prolyl cis-trans
RC54_RS05325	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
RC54_RS05330	COG0559	Belongs to the binding-protein-dependent transport system permease family
RC54_RS05365	COG2193	ferroxidase activity
RC54_RS05370	COG3237	CsbD-like
RC54_RS05380	COG2823	Periplasmic or secreted lipoprotein
RC54_RS05390	COG2201	protein-glutamate methylesterase activity
RC54_RS05425	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RC54_RS05430	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RC54_RS05435	COG1116	anion transmembrane transporter activity
RC54_RS05445	COG2363	Small membrane protein
RC54_RS05465	COG2186	Transcriptional regulator
RC54_RS05470	COG1304	FMN binding
RC54_RS05520	COG2885	chlorophyll binding
RC54_RS05525	COG0823	Involved in the tonB-independent uptake of proteins
RC54_RS05545	COG0824	Thioesterase
RC54_RS05550	COG4221	oxidoreductase activity
RC54_RS05555	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
RC54_RS05560	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
RC54_RS05585	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
RC54_RS05590	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
RC54_RS05595	COG0343	queuine tRNA-ribosyltransferase activity
RC54_RS05600	COG0784	Response regulator, receiver
RC54_RS05600	COG2205	protein histidine kinase activity
RC54_RS05600	COG2198	Histidine kinase
RC54_RS05605	COG2197	response regulator
RC54_RS05620	COG2205	protein histidine kinase activity
RC54_RS05620	COG0784	Response regulator, receiver
RC54_RS05620	COG5002	protein histidine kinase activity
RC54_RS05630	COG1862	Preprotein translocase
RC54_RS05640	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RC54_RS05645	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
RC54_RS05650	COG0697	spore germination
RC54_RS05675	COG1028	Short-chain dehydrogenase reductase Sdr
RC54_RS05690	COG0438	transferase activity, transferring glycosyl groups
RC54_RS05690	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
RC54_RS05695	COG0840	transmembrane signaling receptor activity
RC54_RS05700	COG0840	transmembrane signaling receptor activity
RC54_RS05725	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
RC54_RS05730	COG0573	inorganic phosphate transmembrane transporter activity
RC54_RS05740	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
RC54_RS05745	COG0704	Plays a role in the regulation of phosphate uptake
RC54_RS05760	COG0840	transmembrane signaling receptor activity
RC54_RS05765	COG1028	Short-chain dehydrogenase reductase Sdr
RC54_RS05775	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RC54_RS05825	COG0477	Major facilitator Superfamily
RC54_RS05845	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
RC54_RS05850	COG2200	EAL domain
RC54_RS05865	COG2831	hemolysin activation secretion protein
RC54_RS05870	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
RC54_RS05880	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RC54_RS05885	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RC54_RS05900	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RC54_RS05950	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
RC54_RS05960	COG1902	pentaerythritol trinitrate reductase activity
RC54_RS05970	COG0776	regulation of translation
RC54_RS06070	COG1215	transferase activity, transferring glycosyl groups
RC54_RS06075	COG1215	transferase activity, transferring glycosyl groups
RC54_RS06080	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
RC54_RS06085	COG0457	Tetratricopeptide repeat
RC54_RS06120	COG1196	nuclear chromosome segregation
RC54_RS06130	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
RC54_RS06135	COG4829	muconolactone delta-isomerase
RC54_RS06150	COG3485	protocatechuate 3,4-dioxygenase
RC54_RS06170	COG1028	Short-chain dehydrogenase reductase Sdr
RC54_RS06175	COG0251	oxidation-reduction process
RC54_RS06180	COG2814	Major facilitator Superfamily
RC54_RS06185	COG3135	benzoate transporter
RC54_RS06190	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
RC54_RS06195	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
RC54_RS06210	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
RC54_RS06215	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
RC54_RS06220	COG0840	transmembrane signaling receptor activity
RC54_RS06225	COG4566	intracellular signal transduction
RC54_RS06245	COG4638	Rieske (2fe-2S)
RC54_RS06265	COG4191	Histidine kinase
RC54_RS06280	COG1028	Short-chain dehydrogenase reductase Sdr
RC54_RS06305	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
RC54_RS06335	COG1309	transcriptional regulator
RC54_RS06340	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RC54_RS06345	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RC54_RS06355	COG1309	transcriptional regulator
RC54_RS06360	COG2271	Major facilitator Superfamily
RC54_RS06365	COG0154	amidase activity
RC54_RS06380	COG5001	Diguanylate cyclase
RC54_RS06380	COG3706	GGDEF domain
RC54_RS06380	COG4251	negative regulation of phosphorylation
RC54_RS06380	COG2203	Gaf domain
RC54_RS06400	COG2200	EAL domain
RC54_RS06400	COG2199	diguanylate cyclase activity
RC54_RS06400	COG2203	Gaf domain
RC54_RS06405	COG0583	DNA-binding transcription factor activity
RC54_RS06425	COG3292	Two component regulator propeller
RC54_RS06425	COG0745	RESPONSE REGULATOR receiver
RC54_RS06425	COG2205	protein histidine kinase activity
RC54_RS06455	COG1739	Uncharacterized protein family UPF0029
RC54_RS06465	COG1752	Esterase of the alpha-beta hydrolase superfamily
RC54_RS06475	COG0791	NLP P60 protein
RC54_RS06480	COG3193	protein, possibly involved in utilization of glycolate and propanediol
RC54_RS06485	COG0505	Belongs to the CarA family
RC54_RS06490	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
RC54_RS06495	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
RC54_RS06500	COG1534	Rna-binding protein
RC54_RS06505	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
RC54_RS06510	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RC54_RS06520	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
RC54_RS06530	COG1529	Aldehyde oxidase and xanthine dehydrogenase
RC54_RS06530	COG2010	Cytochrome c
RC54_RS06545	COG0488	(ABC) transporter
RC54_RS06555	COG0728	peptidoglycan biosynthetic process
RC54_RS06560	COG0268	Binds directly to 16S ribosomal RNA
RC54_RS06585	COG1278	Cold shock
RC54_RS06590	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
RC54_RS06595	COG0542	response to heat
RC54_RS06605	COG0756	dUTP diphosphatase activity
RC54_RS06610	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
RC54_RS06615	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
RC54_RS06620	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
RC54_RS06625	COG0196	riboflavin kinase activity
RC54_RS06630	COG1802	Transcriptional regulator
RC54_RS06645	COG3845	ABC transporter
RC54_RS06650	COG1335	isochorismatase
RC54_RS06655	COG1079	Belongs to the binding-protein-dependent transport system permease family
RC54_RS06670	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
RC54_RS06675	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RC54_RS06680	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RC54_RS06690	COG1385	rRNA (uridine-N3-)-methyltransferase activity
RC54_RS06705	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
RC54_RS06715	COG2226	methyltransferase
RC54_RS06720	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
RC54_RS06730	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RC54_RS06735	COG0312	modulator of DNA gyrase
RC54_RS06740	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
RC54_RS06745	COG1666	GTP binding
RC54_RS06750	COG0812	UDP-N-acetylmuramate dehydrogenase activity
RC54_RS06760	COG3123	guanosine phosphorylase activity
RC54_RS06765	COG0137	argininosuccinate synthase activity
RC54_RS06770	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
RC54_RS06775	COG1162	GTPase activity
RC54_RS06780	COG2154	pterin-4-alpha-carbinolamine dehydratase
RC54_RS06785	COG0501	Belongs to the peptidase M48B family
RC54_RS06790	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
RC54_RS06795	COG3318	Belongs to the UPF0149 family
RC54_RS06795	COG3012	SEC-C Motif Domain Protein
RC54_RS06805	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
RC54_RS06865	COG0840	transmembrane signaling receptor activity
RC54_RS06870	COG0519	Catalyzes the synthesis of GMP from XMP
RC54_RS06875	COG1674	ftsk spoiiie
RC54_RS06885	COG1295	ribonuclease BN
RC54_RS06910	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RC54_RS06940	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
RC54_RS06945	COG2918	glutathione biosynthetic process
RC54_RS06950	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
RC54_RS06955	COG0508	dehydrogenase complex catalyzes the overall conversion of
RC54_RS06960	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RC54_RS06965	COG0277	FAD linked oxidase domain protein
RC54_RS06980	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RC54_RS06985	COG1028	Short-chain dehydrogenase reductase Sdr
RC54_RS07010	COG0765	amino acid transport
RC54_RS07015	COG0765	amino acid transport
RC54_RS07020	COG1116	anion transmembrane transporter activity
RC54_RS07025	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RC54_RS07030	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RC54_RS07035	COG1028	Short-chain dehydrogenase reductase Sdr
RC54_RS07050	COG1414	Transcriptional regulator
RC54_RS07055	COG1028	Short-chain dehydrogenase reductase Sdr
RC54_RS07065	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
RC54_RS07070	COG1012	belongs to the aldehyde dehydrogenase family
RC54_RS07080	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RC54_RS07105	COG0840	transmembrane signaling receptor activity
RC54_RS07120	COG0583	DNA-binding transcription factor activity
RC54_RS07140	COG0583	DNA-binding transcription factor activity
RC54_RS07150	COG3842	ATPase activity
RC54_RS07215	COG0473	3-isopropylmalate dehydrogenase activity
RC54_RS07220	COG0676	glucose-6-phosphate 1-epimerase activity
RC54_RS07225	COG0583	DNA-binding transcription factor activity
RC54_RS07235	COG1910	domain protein
RC54_RS07240	COG2223	nitrite transmembrane transporter activity
RC54_RS07255	COG3383	formate dehydrogenase (NAD+) activity
RC54_RS07260	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
RC54_RS07270	COG0583	DNA-binding transcription factor activity
RC54_RS07275	COG2329	Antibiotic biosynthesis monooxygenase
RC54_RS07280	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
RC54_RS07295	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RC54_RS07300	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RC54_RS07300	COG1116	anion transmembrane transporter activity
RC54_RS07325	COG1609	Transcriptional regulator
RC54_RS07335	COG0765	amino acid transport
RC54_RS07340	COG0765	amino acid transport
RC54_RS07355	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RC54_RS07360	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
RC54_RS07375	COG1960	acyl-CoA dehydrogenase activity
RC54_RS07385	COG0228	four-way junction DNA binding
RC54_RS07390	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
RC54_RS07395	COG0336	Belongs to the RNA methyltransferase TrmD family
RC54_RS07400	COG0335	large ribosomal subunit rRNA binding
RC54_RS07405	COG0494	nUDIX hydrolase
RC54_RS07410	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
RC54_RS07420	COG0114	fumarate hydratase activity
RC54_RS07440	COG2205	protein histidine kinase activity
RC54_RS07460	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RC54_RS07465	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RC54_RS07475	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
RC54_RS07475	COG0512	Glutamine amidotransferase of anthranilate synthase
RC54_RS07480	COG0477	Major facilitator Superfamily
RC54_RS07485	COG0697	spore germination
RC54_RS07490	COG0598	Magnesium transport protein CorA
RC54_RS07505	COG0601	transmembrane transport
RC54_RS07510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RC54_RS07515	COG4172	Belongs to the ABC transporter superfamily
RC54_RS07525	COG5001	Diguanylate cyclase
RC54_RS07525	COG4251	negative regulation of phosphorylation
RC54_RS07525	COG2203	Gaf domain
RC54_RS07525	COG3706	GGDEF domain
RC54_RS07530	COG2911	Protein conserved in bacteria
RC54_RS07555	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
RC54_RS07570	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RC54_RS07585	COG2205	protein histidine kinase activity
RC54_RS07585	COG0784	Response regulator, receiver
RC54_RS07590	COG2197	response regulator
RC54_RS07600	COG3121	Chaperone
RC54_RS07610	COG3121	Chaperone
RC54_RS07675	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RC54_RS07715	COG0840	transmembrane signaling receptor activity
RC54_RS07750	COG1104	cysteine desulfurase activity
RC54_RS07755	COG0583	DNA-binding transcription factor activity
RC54_RS07760	COG2072	flavoprotein involved in K transport
RC54_RS07765	COG0601	transmembrane transport
RC54_RS07775	COG0444	Belongs to the ABC transporter superfamily
RC54_RS07780	COG4608	Belongs to the ABC transporter superfamily
RC54_RS07785	COG0747	negative chemotaxis
RC54_RS07810	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RC54_RS07815	COG0583	DNA-binding transcription factor activity
RC54_RS07825	COG1045	serine acetyltransferase
RC54_RS07840	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RC54_RS07875	COG0318	PFAM AMP-dependent synthetase and ligase
RC54_RS07885	COG2132	Multicopper oxidase
RC54_RS07910	COG2267	carboxylic ester hydrolase activity
RC54_RS07915	COG0789	Transcriptional regulator
RC54_RS07920	COG2217	Heavy metal translocating P-type atpase
RC54_RS07940	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RC54_RS07970	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
RC54_RS07975	COG2878	Part of a membrane complex involved in electron transport
RC54_RS07985	COG0492	ferredoxin-NADP+ reductase activity
RC54_RS07990	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
RC54_RS08000	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
RC54_RS08055	COG0123	including yeast histone deacetylase and acetoin utilization protein
RC54_RS08070	COG2226	methyltransferase
RC54_RS08090	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
RC54_RS08095	COG0431	NADPH-dependent FMN reductase
RC54_RS08100	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RC54_RS08105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RC54_RS08110	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RC54_RS08115	COG1116	anion transmembrane transporter activity
RC54_RS08120	COG3585	molybdate ion transport
RC54_RS08135	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
RC54_RS08140	COG4208	sulfate ABC transporter
RC54_RS08145	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
RC54_RS08150	COG0583	DNA-binding transcription factor activity
RC54_RS08200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RC54_RS08205	COG2814	Major facilitator Superfamily
RC54_RS08220	COG1522	sequence-specific DNA binding
RC54_RS08225	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
RC54_RS08225	COG2169	Transcriptional regulator
RC54_RS08230	COG3145	DNA-N1-methyladenine dioxygenase activity
RC54_RS08235	COG3210	domain, Protein
RC54_RS08255	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RC54_RS08265	COG0243	molybdopterin cofactor binding
RC54_RS08275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RC54_RS08300	COG1477	protein flavinylation
RC54_RS08305	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
RC54_RS08310	COG1253	flavin adenine dinucleotide binding
RC54_RS08355	COG0583	DNA-binding transcription factor activity
RC54_RS08370	COG0513	Belongs to the DEAD box helicase family
RC54_RS08385	COG0483	inositol monophosphate 1-phosphatase activity
RC54_RS08400	COG1187	pseudouridine synthase activity
RC54_RS08410	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
RC54_RS08420	COG2833	Protein of unknown function (DUF455)
RC54_RS08430	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
RC54_RS08455	COG0028	Belongs to the TPP enzyme family
RC54_RS08465	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
RC54_RS08480	COG0688	phosphatidylethanolamine metabolic process
RC54_RS08485	COG1183	phosphatidylcholine synthase activity
RC54_RS08505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RC54_RS08530	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
RC54_RS08550	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
RC54_RS08555	COG1185	polyribonucleotide nucleotidyltransferase activity
RC54_RS08560	COG1252	NADH dehydrogenase
RC54_RS08580	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
RC54_RS08585	COG1984	allophanate hydrolase subunit 2
RC54_RS08590	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
RC54_RS08600	COG1028	Short-chain dehydrogenase reductase Sdr
RC54_RS08600	COG3321	synthase
RC54_RS08600	COG0604	alcohol dehydrogenase
RC54_RS08605	COG0149	triose-phosphate isomerase activity
RC54_RS08610	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
RC54_RS08620	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RC54_RS08625	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RC54_RS08630	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RC54_RS08635	COG0649	NAD binding
RC54_RS08650	COG1034	ATP synthesis coupled electron transport
RC54_RS08655	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
RC54_RS08660	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RC54_RS08670	COG0713	ATP synthesis coupled electron transport
RC54_RS08685	COG1007	ATP synthesis coupled electron transport
RC54_RS08695	COG0494	nUDIX hydrolase
RC54_RS08730	COG2267	carboxylic ester hydrolase activity
RC54_RS08755	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
RC54_RS08770	COG4115	mRNA cleavage
RC54_RS08780	COG1028	Short-chain dehydrogenase reductase Sdr
RC54_RS08815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RC54_RS08840	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
RC54_RS08850	COG0697	spore germination
RC54_RS08860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RC54_RS08875	COG1942	4-Oxalocrotonate Tautomerase
RC54_RS08900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RC54_RS08905	COG0842	Transport permease protein
RC54_RS08905	COG1129	ABC transporter
RC54_RS08910	COG0842	Transport permease protein
RC54_RS08945	COG0583	DNA-binding transcription factor activity
RC54_RS08960	COG4172	Belongs to the ABC transporter superfamily
RC54_RS08965	COG0747	negative chemotaxis
RC54_RS08990	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
RC54_RS09000	COG0405	Gamma-glutamyltransferase
RC54_RS09005	COG4608	Belongs to the ABC transporter superfamily
RC54_RS09010	COG0444	Belongs to the ABC transporter superfamily
RC54_RS09015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RC54_RS09030	COG1846	Transcriptional regulator
RC54_RS09040	COG0400	carboxylic ester hydrolase activity
RC54_RS09050	COG0521	Mo-molybdopterin cofactor biosynthetic process
RC54_RS09055	COG3028	Belongs to the UPF0307 family
RC54_RS09060	COG0312	modulator of DNA gyrase
RC54_RS09065	COG0477	Major facilitator Superfamily
RC54_RS09075	COG0415	Belongs to the DNA photolyase family
RC54_RS09080	COG0840	transmembrane signaling receptor activity
RC54_RS09090	COG0557	exoribonuclease II activity
RC54_RS09095	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RC54_RS09100	COG1045	serine acetyltransferase
RC54_RS09105	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
RC54_RS09110	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
RC54_RS09130	COG0215	cysteine-tRNA ligase activity
RC54_RS09140	COG0825	malonyl-CoA metabolic process
RC54_RS09145	COG0037	tRNA processing
RC54_RS09160	COG1280	lysine exporter protein (LysE YggA)
RC54_RS09185	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
RC54_RS09200	COG0303	'Molybdopterin
RC54_RS09205	COG0746	molybdenum cofactor guanylyltransferase activity
RC54_RS09210	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
RC54_RS09215	COG1530	ribonuclease E activity
RC54_RS09245	COG0248	Ppx GppA phosphatase
RC54_RS09250	COG1840	ABC-type Fe3 transport system, periplasmic component
RC54_RS09260	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
RC54_RS09260	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RC54_RS09265	COG0347	Belongs to the P(II) protein family
RC54_RS09270	COG1012	belongs to the aldehyde dehydrogenase family
RC54_RS09280	COG3284	Transcriptional regulator
RC54_RS09295	COG2840	Smr protein MutS2
RC54_RS09305	COG0492	ferredoxin-NADP+ reductase activity
RC54_RS09310	COG1674	ftsk spoiiie
RC54_RS09315	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
RC54_RS09320	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
RC54_RS09325	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
RC54_RS09360	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
RC54_RS09365	COG5001	Diguanylate cyclase
RC54_RS09365	COG3300	MHYT domain
RC54_RS09380	COG1609	Transcriptional regulator
RC54_RS09400	COG0424	maF-like protein
RC54_RS09410	COG0333	Belongs to the bacterial ribosomal protein bL32 family
RC54_RS09415	COG0416	fatty acid biosynthetic process
RC54_RS09420	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
RC54_RS09430	COG1028	Short-chain dehydrogenase reductase Sdr
RC54_RS09435	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RC54_RS09440	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
RC54_RS09465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RC54_RS09475	COG0481	GTPase activity
RC54_RS09480	COG0681	Belongs to the peptidase S26 family
RC54_RS09485	COG0571	ribonuclease III activity
RC54_RS09490	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
RC54_RS09495	COG1381	Involved in DNA repair and RecF pathway recombination
RC54_RS09500	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
RC54_RS09505	COG0736	holo-[acyl-carrier-protein] synthase activity
RC54_RS09515	COG0322	excinuclease ABC activity
RC54_RS09550	COG0835	chemotaxis
RC54_RS09550	COG0784	Response regulator, receiver
RC54_RS09555	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
RC54_RS09560	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
RC54_RS09565	COG0406	alpha-ribazole phosphatase activity
RC54_RS09585	COG2879	small protein
RC54_RS09600	COG4251	negative regulation of phosphorylation
RC54_RS09600	COG5001	Diguanylate cyclase
RC54_RS09600	COG2203	Gaf domain
RC54_RS09600	COG3706	GGDEF domain
RC54_RS09610	COG0501	Belongs to the peptidase M48B family
RC54_RS09615	COG4651	solute:proton antiporter activity
RC54_RS09615	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
RC54_RS09620	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
RC54_RS09665	COG0251	oxidation-reduction process
RC54_RS09670	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
RC54_RS09695	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
RC54_RS09700	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
RC54_RS09705	COG0291	Belongs to the bacterial ribosomal protein bL35 family
RC54_RS09710	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
RC54_RS09715	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
RC54_RS09720	COG0072	phenylalanine-tRNA ligase activity
RC54_RS09720	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RC54_RS09725	COG0776	regulation of translation
RC54_RS09790	COG0438	transferase activity, transferring glycosyl groups
RC54_RS09800	COG2755	lipolytic protein G-D-S-L family
RC54_RS09800	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
RC54_RS09820	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
RC54_RS09850	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
RC54_RS09850	COG0517	IMP dehydrogenase activity
RC54_RS09860	COG1045	serine acetyltransferase
RC54_RS09875	COG1929	Belongs to the glycerate kinase type-1 family
RC54_RS09925	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
RC54_RS09930	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
RC54_RS09935	COG2201	protein-glutamate methylesterase activity
RC54_RS09940	COG0745	RESPONSE REGULATOR receiver
RC54_RS09950	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
RC54_RS09955	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
RC54_RS09970	COG1191	sigma factor activity
RC54_RS09990	COG1815	bacterial-type flagellum-dependent cell motility
RC54_RS10000	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
RC54_RS10010	COG4787	bacterial-type flagellum-dependent cell motility
RC54_RS10020	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
RC54_RS10025	COG1706	bacterial-type flagellum-dependent cell motility
RC54_RS10030	COG3951	Flagellar rod assembly protein muramidase FlgJ
RC54_RS10030	COG1705	Flagellar rod assembly protein muramidase FlgJ
RC54_RS10055	COG1338	Plays a role in the flagellum-specific transport system
RC54_RS10060	COG3190	flagellar
RC54_RS10065	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
RC54_RS10075	COG1580	Controls the rotational direction of flagella during chemotaxis
RC54_RS10105	COG1766	The M ring may be actively involved in energy transduction
RC54_RS10110	COG1677	Flagellar hook-basal body complex protein FliE
RC54_RS10115	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
RC54_RS10120	COG2257	FlhB HrpN YscU SpaS Family
RC54_RS10140	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
RC54_RS10160	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
RC54_RS10165	COG0360	Binds together with S18 to 16S ribosomal RNA
RC54_RS10175	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
RC54_RS10180	COG0359	binds to the 23S rRNA
RC54_RS10185	COG0305	Participates in initiation and elongation during chromosome replication
RC54_RS10195	COG0306	phosphate transporter
RC54_RS10200	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
RC54_RS10205	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
RC54_RS10210	COG0726	polysaccharide deacetylase
RC54_RS10220	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
RC54_RS10220	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RC54_RS10225	COG0463	Glycosyl transferase, family 2
RC54_RS10230	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
RC54_RS10235	COG2076	Multidrug Resistance protein
RC54_RS10250	COG0436	Aminotransferase
RC54_RS10280	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
RC54_RS10295	COG0314	molybdopterin synthase activity
RC54_RS10300	COG1914	H( )-stimulated, divalent metal cation uptake system
RC54_RS10315	COG1566	PFAM secretion protein HlyD family protein
RC54_RS10335	COG0583	DNA-binding transcription factor activity
RC54_RS10340	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
RC54_RS10345	COG0542	response to heat
RC54_RS10355	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
RC54_RS10360	COG1289	transmembrane transporter activity
RC54_RS10365	COG2224	Isocitrate lyase
RC54_RS10375	COG4149	molybdate abc transporter
RC54_RS10380	COG0725	ABC transporter, periplasmic molybdate-binding protein
RC54_RS10390	COG0038	chloride channel
RC54_RS10395	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
RC54_RS10400	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
RC54_RS10425	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
RC54_RS10430	COG0583	DNA-binding transcription factor activity
RC54_RS10435	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
RC54_RS10440	COG1758	RNA polymerase activity
RC54_RS10445	COG0194	GDP metabolic process
RC54_RS10450	COG1561	YicC-like family, N-terminal region
RC54_RS10455	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
RC54_RS10460	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
RC54_RS10465	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RC54_RS10520	COG1475	DNA binding
RC54_RS10645	COG4386	tail sheath protein
RC54_RS10675	COG4384	Bacteriophage Mu Gp45 protein
RC54_RS10690	COG3778	Protein conserved in bacteria
RC54_RS10735	COG0582	viral genome integration into host DNA
RC54_RS10745	COG0527	aspartate kinase activity
RC54_RS10755	COG0583	DNA-binding transcription factor activity
RC54_RS10765	COG1214	PFAM Peptidase M22, glycoprotease
RC54_RS10775	COG1573	uracil-dna glycosylase
RC54_RS10785	COG0477	Major facilitator Superfamily
RC54_RS10790	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
RC54_RS10820	COG0765	amino acid transport
RC54_RS10825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RC54_RS10830	COG0488	(ABC) transporter
RC54_RS10835	COG2890	protein-(glutamine-N5) methyltransferase activity
RC54_RS10840	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RC54_RS10845	COG1393	Belongs to the ArsC family
RC54_RS10850	COG2171	N-acyltransferase activity
RC54_RS10855	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
RC54_RS10860	COG0840	transmembrane signaling receptor activity
RC54_RS10875	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
RC54_RS10880	COG1210	Utp--glucose-1-phosphate uridylyltransferase
RC54_RS10885	COG0242	peptide deformylase activity
RC54_RS10890	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
RC54_RS10890	COG0189	ligase activity
RC54_RS10895	COG1181	Belongs to the D-alanine--D-alanine ligase family
RC54_RS10895	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
RC54_RS10900	COG1132	(ABC) transporter
RC54_RS10915	COG1187	pseudouridine synthase activity
RC54_RS10920	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
RC54_RS10925	COG0024	Methionine aminopeptidase
RC54_RS10930	COG0052	Belongs to the universal ribosomal protein uS2 family
RC54_RS10935	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
RC54_RS10940	COG0528	UMP kinase activity
RC54_RS10945	COG0233	cytoplasmic translational termination
RC54_RS10950	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
RC54_RS10955	COG0575	Belongs to the CDS family
RC54_RS10960	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
RC54_RS10965	COG0750	zinc metalloprotease
RC54_RS10980	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
RC54_RS10985	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
RC54_RS10990	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
RC54_RS11000	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
RC54_RS11005	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RC54_RS11015	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
RC54_RS11045	COG2205	protein histidine kinase activity
RC54_RS11050	COG0745	RESPONSE REGULATOR receiver
RC54_RS11060	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
RC54_RS11070	COG2914	Belongs to the UPF0125 (RnfH) family
RC54_RS11075	COG0516	GMP reductase activity
RC54_RS11075	COG0517	IMP dehydrogenase activity
RC54_RS11080	COG0519	Catalyzes the synthesis of GMP from XMP
RC54_RS11080	COG0518	GMP synthase (glutamine-hydrolyzing) activity
RC54_RS11100	COG0602	queuosine metabolic process
RC54_RS11105	COG0720	synthase
RC54_RS11115	COG1619	proteins homologs of microcin C7 resistance protein MccF
RC54_RS11125	COG0488	(ABC) transporter
RC54_RS11130	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
RC54_RS11145	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
RC54_RS11150	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
RC54_RS11165	COG2851	Citrate transporter
RC54_RS11170	COG0583	DNA-binding transcription factor activity
RC54_RS11175	COG0477	Major facilitator Superfamily
RC54_RS11185	COG1840	ABC-type Fe3 transport system, periplasmic component
RC54_RS11190	COG4149	molybdate abc transporter
RC54_RS11195	COG3842	ATPase activity
RC54_RS11205	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
RC54_RS11220	COG4181	ATPase activity
RC54_RS11230	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
RC54_RS11230	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
RC54_RS11235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RC54_RS11240	COG0047	phosphoribosylformylglycinamidine synthase activity
RC54_RS11240	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
RC54_RS11250	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
RC54_RS11260	COG2917	probably involved in intracellular septation
RC54_RS11265	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
RC54_RS11270	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
RC54_RS11320	COG2271	Major facilitator Superfamily
RC54_RS11330	COG1012	belongs to the aldehyde dehydrogenase family
RC54_RS11350	COG3706	GGDEF domain
RC54_RS11355	COG0166	Belongs to the GPI family
RC54_RS11365	COG4251	negative regulation of phosphorylation
RC54_RS11370	COG0784	Response regulator, receiver
RC54_RS11375	COG2205	protein histidine kinase activity
RC54_RS11390	COG4191	Histidine kinase
RC54_RS11390	COG0784	Response regulator, receiver
RC54_RS11420	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RC54_RS11435	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RC54_RS11440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RC54_RS11450	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RC54_RS11455	COG0681	Belongs to the peptidase S26 family
RC54_RS11460	COG1309	transcriptional regulator
RC54_RS11475	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RC54_RS11480	COG2198	Histidine kinase
RC54_RS11480	COG0643	Histidine kinase
RC54_RS11500	COG0745	RESPONSE REGULATOR receiver
RC54_RS11520	COG0038	chloride channel
RC54_RS11560	COG0477	Major facilitator Superfamily
RC54_RS11565	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
RC54_RS11570	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
RC54_RS11575	COG1845	cytochrome c oxidase, subunit III
RC54_RS11580	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
RC54_RS11595	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
RC54_RS11620	COG0784	Response regulator, receiver
RC54_RS11620	COG4191	Histidine kinase
RC54_RS11625	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
RC54_RS11635	COG0156	8-amino-7-oxononanoate synthase activity
RC54_RS11645	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
RC54_RS11660	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RC54_RS11665	COG0583	DNA-binding transcription factor activity
RC54_RS11670	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RC54_RS11690	COG0417	DNA replication proofreading
RC54_RS11700	COG2814	Major facilitator Superfamily
RC54_RS11705	COG0840	transmembrane signaling receptor activity
RC54_RS11745	COG0642	Histidine kinase
RC54_RS11755	COG0642	Histidine kinase
RC54_RS11765	COG1309	transcriptional regulator
RC54_RS11775	COG1595	DNA-templated transcription, initiation
RC54_RS11785	COG4774	siderophore transport
RC54_RS11790	COG1595	DNA-templated transcription, initiation
RC54_RS11800	COG4774	siderophore transport
RC54_RS11825	COG1132	(ABC) transporter
RC54_RS11830	COG2375	cellular response to nickel ion
RC54_RS11830	COG1132	(ABC) transporter
RC54_RS11840	COG4771	TonB-dependent receptor
RC54_RS11850	COG2226	methyltransferase
RC54_RS11865	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RC54_RS11865	COG2226	methyltransferase
RC54_RS11865	COG3433	isochorismatase activity
RC54_RS11870	COG3433	isochorismatase activity
RC54_RS11870	COG2226	methyltransferase
RC54_RS11870	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RC54_RS11875	COG2977	Belongs to the P-Pant transferase superfamily
RC54_RS11880	COG2963	transposase activity
RC54_RS11890	COG0735	belongs to the Fur family
RC54_RS11915	COG0318	PFAM AMP-dependent synthetase and ligase
RC54_RS11930	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RC54_RS11960	COG2091	lysine biosynthetic process via aminoadipic acid
RC54_RS12120	COG4128	Pfam Zonular occludens toxin
RC54_RS12290	COG0312	modulator of DNA gyrase
RC54_RS12295	COG0312	modulator of DNA gyrase
RC54_RS12325	COG1522	sequence-specific DNA binding
RC54_RS12330	COG1595	DNA-templated transcription, initiation
RC54_RS12340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RC54_RS12375	COG0583	DNA-binding transcription factor activity
RC54_RS12395	COG2814	Major facilitator Superfamily
RC54_RS12520	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
RC54_RS12525	COG0864	Transcriptional regulator
RC54_RS12540	COG1276	copper resistance
RC54_RS12545	COG2372	response to copper ion
RC54_RS12575	COG1045	serine acetyltransferase
RC54_RS12585	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RC54_RS12590	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
RC54_RS12600	COG2223	nitrite transmembrane transporter activity
RC54_RS12645	COG0402	S-adenosylhomocysteine deaminase activity
RC54_RS12650	COG1104	cysteine desulfurase activity
RC54_RS12655	COG0822	iron-sulfur transferase activity
RC54_RS12660	COG0316	Belongs to the HesB IscA family
RC54_RS12670	COG0443	Heat shock 70 kDa protein
RC54_RS12675	COG0633	Ferredoxin
RC54_RS12730	COG4231	catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates
RC54_RS12735	COG5420	small protein containing a coiled-coil domain
RC54_RS12750	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
RC54_RS12755	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
RC54_RS12760	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
RC54_RS12775	COG0745	RESPONSE REGULATOR receiver
RC54_RS12805	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
RC54_RS12815	COG5554	nitrogen fixation
RC54_RS12820	COG1104	cysteine desulfurase activity
RC54_RS12835	COG5554	nitrogen fixation
RC54_RS12850	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
RC54_RS12870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RC54_RS12900	COG1957	nucleoside hydrolase
RC54_RS12905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RC54_RS12920	COG4603	Belongs to the binding-protein-dependent transport system permease family
RC54_RS12925	COG3845	ABC transporter
RC54_RS12935	COG2188	Transcriptional regulator
RC54_RS12940	COG0811	peptide transport
RC54_RS12965	COG0840	transmembrane signaling receptor activity
RC54_RS13085	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
RC54_RS13095	COG4794	Type iii secretion
RC54_RS13140	COG4789	Type iii secretion
RC54_RS13185	COG0500	methyltransferase
RC54_RS13240	COG2843	Capsule synthesis protein
RC54_RS13255	COG4608	Belongs to the ABC transporter superfamily
RC54_RS13265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RC54_RS13270	COG0601	transmembrane transport
RC54_RS13275	COG0747	negative chemotaxis
RC54_RS13300	COG1028	Short-chain dehydrogenase reductase Sdr
RC54_RS13320	COG1454	alcohol dehydrogenase
RC54_RS13330	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
RC54_RS13335	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
RC54_RS13340	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RC54_RS13350	COG0765	amino acid transport
RC54_RS13355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RC54_RS13365	COG1012	belongs to the aldehyde dehydrogenase family
RC54_RS13375	COG0174	glutamine synthetase
RC54_RS13380	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
RC54_RS13405	COG1309	transcriptional regulator
RC54_RS13410	COG0154	amidase activity
RC54_RS13415	COG0531	amino acid
RC54_RS13420	COG2011	ABC-type metal ion transport system permease component
RC54_RS13425	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
RC54_RS13430	COG1464	Belongs to the NlpA lipoprotein family
RC54_RS13445	COG2204	response regulator
RC54_RS13465	COG0730	response to heat
RC54_RS13475	COG3002	Belongs to the UPF0753 family
RC54_RS13480	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
RC54_RS13485	COG0583	DNA-binding transcription factor activity
RC54_RS13495	COG0640	Transcriptional regulator
RC54_RS13545	COG2982	Protein involved in outer membrane biogenesis
RC54_RS13555	COG1869	D-ribose catabolic process
RC54_RS13560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RC54_RS13565	COG1609	Transcriptional regulator
RC54_RS13570	COG1172	Belongs to the binding-protein-dependent transport system permease family
RC54_RS13575	COG1129	ABC transporter
RC54_RS13580	COG1879	ABC-type sugar transport system periplasmic component
RC54_RS13585	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
RC54_RS13610	COG0402	S-adenosylhomocysteine deaminase activity
RC54_RS13620	COG1126	abc transporter atp-binding protein
RC54_RS13625	COG0765	amino acid transport
RC54_RS13630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RC54_RS13640	COG1802	Transcriptional regulator
RC54_RS13655	COG0277	FAD linked oxidase domain protein
RC54_RS13660	COG1172	Belongs to the binding-protein-dependent transport system permease family
RC54_RS13665	COG1129	ABC transporter
RC54_RS13690	COG1070	Carbohydrate kinase
RC54_RS13695	COG1012	belongs to the aldehyde dehydrogenase family
RC54_RS13700	COG1028	Short-chain dehydrogenase reductase Sdr
RC54_RS13725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RC54_RS13755	COG0322	excinuclease ABC activity
RC54_RS13765	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
RC54_RS13770	COG0028	Belongs to the TPP enzyme family
RC54_RS13805	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
RC54_RS13835	COG1640	4-alpha-glucanotransferase
RC54_RS13840	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
RC54_RS13850	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
RC54_RS13855	COG0297	glycogen (starch) synthase activity
RC54_RS13865	COG3604	Transcriptional regulator
RC54_RS13880	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
RC54_RS13905	COG4302	ethanolamine ammonia-lyase activity
RC54_RS13915	COG0531	amino acid
RC54_RS13920	COG2207	Transcriptional regulator
RC54_RS13930	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
RC54_RS13955	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RC54_RS13960	COG1116	anion transmembrane transporter activity
RC54_RS13960	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RC54_RS13970	COG0642	Histidine kinase
RC54_RS13980	COG2264	protein methyltransferase activity
RC54_RS13990	COG1741	Belongs to the pirin family
RC54_RS14005	COG0583	DNA-binding transcription factor activity
RC54_RS14015	COG2814	Major facilitator Superfamily
RC54_RS14025	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RC54_RS14030	COG0671	phosphoesterase, PA-phosphatase related
RC54_RS14055	COG0523	cobalamin synthesis protein
RC54_RS14060	COG1469	GTP cyclohydrolase I activity
RC54_RS14080	COG1024	Enoyl-CoA hydratase
RC54_RS14085	COG1960	acyl-CoA dehydrogenase activity
RC54_RS14095	COG2203	Gaf domain
RC54_RS14095	COG5001	Diguanylate cyclase
RC54_RS14095	COG3706	GGDEF domain
RC54_RS14095	COG4251	negative regulation of phosphorylation
RC54_RS14125	COG0625	glutathione transferase activity
RC54_RS14140	COG0436	Aminotransferase
RC54_RS14180	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RC54_RS14190	COG2197	response regulator
RC54_RS14195	COG4585	Histidine kinase
RC54_RS14200	COG3852	Histidine kinase
RC54_RS14205	COG0567	Dehydrogenase, E1 component
RC54_RS14210	COG0840	transmembrane signaling receptor activity
RC54_RS14225	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RC54_RS14235	COG0765	amino acid transport
RC54_RS14240	COG1126	abc transporter atp-binding protein
RC54_RS14270	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
RC54_RS14275	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
RC54_RS14280	COG0740	serine-type endopeptidase activity
RC54_RS14285	COG0544	peptidyl-prolyl cis-trans isomerase activity
RC54_RS14290	COG3045	CreA protein
RC54_RS14335	COG2273	Hydrolase Family 16
RC54_RS14335	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
RC54_RS14345	COG1562	ergosterol biosynthetic process
RC54_RS14365	COG1304	FMN binding
RC54_RS14375	COG0084	hydrolase, TatD family'
RC54_RS14380	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
RC54_RS14395	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
RC54_RS14400	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
RC54_RS14420	COG0584	glycerophosphoryl diester phosphodiesterase
RC54_RS14425	COG3511	phospholipase C
RC54_RS14430	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
RC54_RS14435	COG0848	biopolymer transport protein
RC54_RS14440	COG0811	peptide transport
RC54_RS14450	COG1609	Transcriptional regulator
RC54_RS14460	COG1175	transmembrane transport
RC54_RS14465	COG0395	ABC-type sugar transport system, permease component
RC54_RS14480	COG1301	dicarboxylic acid transport
RC54_RS14485	COG0840	transmembrane signaling receptor activity
RC54_RS14505	COG0583	DNA-binding transcription factor activity
RC54_RS14520	COG2814	Major facilitator Superfamily
RC54_RS14525	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
RC54_RS14590	COG2205	protein histidine kinase activity
RC54_RS14590	COG0784	Response regulator, receiver
RC54_RS14610	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RC54_RS14615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RC54_RS14625	COG1492	cobalamin metabolic process
RC54_RS14645	COG0778	Nitroreductase
RC54_RS14685	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
RC54_RS14690	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
RC54_RS14695	COG1648	precorrin-2 dehydrogenase activity
RC54_RS14695	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
RC54_RS14710	COG3411	Ferredoxin
RC54_RS14755	COG1210	Utp--glucose-1-phosphate uridylyltransferase
RC54_RS14765	COG3217	Mosc domain protein beta barrel domain protein
RC54_RS14765	COG0633	Ferredoxin
RC54_RS14775	COG1607	acyl-coa hydrolase
RC54_RS14780	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
RC54_RS14820	COG3052	prosthetic group binding
RC54_RS14840	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
RC54_RS14845	COG1802	Transcriptional regulator
RC54_RS14850	COG0564	pseudouridine synthase activity
RC54_RS14855	COG3550	peptidyl-serine autophosphorylation
RC54_RS14920	COG1566	PFAM secretion protein HlyD family protein
RC54_RS14925	COG2814	Major facilitator Superfamily
RC54_RS14930	COG0583	DNA-binding transcription factor activity
RC54_RS14935	COG0667	Aldo Keto reductase
RC54_RS14945	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
RC54_RS14950	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
RC54_RS14965	COG0667	Aldo Keto reductase
RC54_RS14975	COG2824	Alkylphosphonate utilization operon protein PhnA
RC54_RS14985	COG0672	)-iron permease
RC54_RS14990	COG4633	Protein conserved in bacteria
RC54_RS15035	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
RC54_RS15040	COG0148	phosphopyruvate hydratase activity
RC54_RS15045	COG0504	CTP synthase activity
RC54_RS15050	COG0596	Alpha beta hydrolase
RC54_RS15060	COG0084	hydrolase, TatD family'
RC54_RS15070	COG1136	(ABC) transporter
RC54_RS15075	COG4591	ABC-type transport system involved in lipoprotein release permease component
RC54_RS15080	COG0210	DNA helicase
RC54_RS15090	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
RC54_RS15115	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
RC54_RS15140	COG0583	DNA-binding transcription factor activity
RC54_RS15145	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
RC54_RS15175	COG1960	acyl-CoA dehydrogenase activity
RC54_RS15180	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
RC54_RS15185	COG0583	DNA-binding transcription factor activity
RC54_RS15195	COG1028	Short-chain dehydrogenase reductase Sdr
RC54_RS15260	COG1960	acyl-CoA dehydrogenase activity
RC54_RS15265	COG0183	Belongs to the thiolase family
RC54_RS15275	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RC54_RS15290	COG2072	flavoprotein involved in K transport
RC54_RS15300	COG0438	transferase activity, transferring glycosyl groups
RC54_RS15305	COG2144	transferase activity, transferring acyl groups
RC54_RS15330	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RC54_RS15340	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RC54_RS15345	COG2274	protein secretion by the type I secretion system
RC54_RS15355	COG1538	Outer membrane efflux protein
RC54_RS15360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RC54_RS15365	COG2274	protein secretion by the type I secretion system
RC54_RS15410	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
RC54_RS15415	COG1127	ABC transporter
RC54_RS15430	COG0583	DNA-binding transcription factor activity
RC54_RS15435	COG1346	cytolysis
RC54_RS15450	COG1881	PFAM PEBP family protein
RC54_RS15460	COG1285	pathogenesis
RC54_RS15465	COG2223	nitrite transmembrane transporter activity
RC54_RS15470	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RC54_RS15475	COG2146	nitrite reductase [NAD(P)H] activity
RC54_RS15480	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RC54_RS15485	COG0243	molybdopterin cofactor binding
RC54_RS15525	COG3064	Membrane
RC54_RS15535	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
RC54_RS15545	COG2959	enzyme of heme biosynthesis
RC54_RS15555	COG0181	hydroxymethylbilane synthase activity
RC54_RS15560	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
RC54_RS15580	COG0165	Argininosuccinate lyase
RC54_RS15640	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RC54_RS15650	COG0583	DNA-binding transcription factor activity
RC54_RS15655	COG2814	Major facilitator Superfamily
RC54_RS15670	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
RC54_RS15675	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
RC54_RS15680	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
RC54_RS15685	COG0330	HflC and HflK could
RC54_RS15690	COG0330	HflC and HflK could
RC54_RS15695	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
RC54_RS15700	COG1923	regulation of RNA biosynthetic process
RC54_RS15705	COG1160	GTP binding
RC54_RS15720	COG0124	histidyl-tRNA synthetase
RC54_RS15725	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
RC54_RS15735	COG0820	rRNA (adenine-C2-)-methyltransferase activity
RC54_RS15740	COG0105	UTP biosynthetic process
RC54_RS15745	COG0670	Belongs to the BI1 family
RC54_RS15750	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
RC54_RS15755	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
RC54_RS15760	COG4942	peptidase
RC54_RS15760	COG1388	LysM domain
RC54_RS15765	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
RC54_RS15770	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
RC54_RS15780	COG1199	ATP-dependent helicase activity
RC54_RS15795	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
RC54_RS15800	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RC54_RS15805	COG0508	dehydrogenase complex catalyzes the overall conversion of
RC54_RS15810	COG0567	Dehydrogenase, E1 component
RC54_RS15815	COG0372	Belongs to the citrate synthase family
RC54_RS15820	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
RC54_RS15825	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
RC54_RS15830	COG1053	succinate dehydrogenase
RC54_RS15845	COG2188	Transcriptional regulator
RC54_RS15850	COG0039	L-malate dehydrogenase activity
RC54_RS15865	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
RC54_RS15875	COG0835	chemotaxis
RC54_RS15885	COG0745	RESPONSE REGULATOR receiver
RC54_RS15920	COG0626	cystathionine gamma-synthase activity
RC54_RS15930	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
RC54_RS15940	COG1028	Short-chain dehydrogenase reductase Sdr
RC54_RS15945	COG3243	poly(R)-hydroxyalkanoic acid synthase
RC54_RS15975	COG0564	pseudouridine synthase activity
RC54_RS15985	COG3022	response to hydroperoxide
RC54_RS16000	COG0436	Aminotransferase
RC54_RS16005	COG0625	glutathione transferase activity
RC54_RS16010	COG3447	MASE1 domain protein
RC54_RS16010	COG5001	Diguanylate cyclase
RC54_RS16010	COG5002	protein histidine kinase activity
RC54_RS16020	COG5001	Diguanylate cyclase
RC54_RS16020	COG2203	Gaf domain
RC54_RS16020	COG3706	GGDEF domain
RC54_RS16020	COG4251	negative regulation of phosphorylation
RC54_RS16050	COG0840	transmembrane signaling receptor activity
RC54_RS16060	COG0560	Phosphoserine phosphatase
RC54_RS16065	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
RC54_RS16070	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
RC54_RS16075	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
RC54_RS16080	COG1278	Cold shock
RC54_RS16085	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
RC54_RS16090	COG0583	DNA-binding transcription factor activity
RC54_RS16115	COG2814	Major facilitator Superfamily
RC54_RS16155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RC54_RS16165	COG4943	cyclic-guanylate-specific phosphodiesterase activity
RC54_RS16180	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
RC54_RS16185	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
RC54_RS16190	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
RC54_RS16220	COG1294	oxidase, subunit
RC54_RS16235	COG1764	response to oxidative stress
RC54_RS16240	COG1846	Transcriptional regulator
RC54_RS16250	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
RC54_RS16255	COG2186	Transcriptional regulator
RC54_RS16260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RC54_RS16280	COG0583	DNA-binding transcription factor activity
RC54_RS16285	COG0693	protein deglycase activity
RC54_RS16305	COG1024	Enoyl-CoA hydratase
RC54_RS16335	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
RC54_RS16340	COG0489	protein tyrosine kinase activity
RC54_RS16345	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RC54_RS16345	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RC54_RS16355	COG2390	Transcriptional regulator
RC54_RS16360	COG3842	ATPase activity
RC54_RS16375	COG0395	ABC-type sugar transport system, permease component
RC54_RS16390	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
RC54_RS16395	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
RC54_RS16400	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RC54_RS16410	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
RC54_RS16415	COG4139	cobalamin transport
RC54_RS16420	COG4774	siderophore transport
RC54_RS16425	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
RC54_RS16430	COG0784	Response regulator, receiver
RC54_RS16430	COG2198	Histidine kinase
RC54_RS16430	COG0643	Histidine kinase
RC54_RS16435	COG0583	DNA-binding transcription factor activity
RC54_RS16440	COG0730	response to heat
RC54_RS16445	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RC54_RS16455	COG0175	sulfate reduction
RC54_RS16465	COG2895	sulfate adenylyltransferase (ATP) activity
RC54_RS16480	COG0795	lipopolysaccharide-transporting ATPase activity
RC54_RS16485	COG0795	lipopolysaccharide-transporting ATPase activity
RC54_RS16490	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
RC54_RS16500	COG1902	pentaerythritol trinitrate reductase activity
RC54_RS16515	COG0708	Exodeoxyribonuclease III
RC54_RS16525	COG1247	-acetyltransferase
RC54_RS16560	COG0840	transmembrane signaling receptor activity
RC54_RS16575	COG0583	DNA-binding transcription factor activity
RC54_RS16590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RC54_RS16595	COG2204	response regulator
RC54_RS16600	COG3852	Histidine kinase
RC54_RS16605	COG0174	glutamine synthetase
RC54_RS16615	COG2205	protein histidine kinase activity
RC54_RS16615	COG0784	Response regulator, receiver
RC54_RS16660	COG2975	iron-sulfur cluster assembly
RC54_RS16670	COG0443	Heat shock 70 kDa protein
RC54_RS16680	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
RC54_RS16685	COG0316	Belongs to the HesB IscA family
RC54_RS16690	COG0822	iron-sulfur transferase activity
RC54_RS16695	COG1104	cysteine desulfurase activity
RC54_RS16705	COG2186	Transcriptional regulator
RC54_RS16710	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RC54_RS16720	COG2706	6-phosphogluconolactonase activity
RC54_RS16725	COG2721	sulfolactate sulfo-lyase activity
RC54_RS16730	COG2271	Major facilitator Superfamily
RC54_RS16735	COG0701	Predicted permease
RC54_RS16740	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
RC54_RS16745	COG0709	Synthesizes selenophosphate from selenide and ATP
RC54_RS16765	COG0556	nucleotide-excision repair
RC54_RS16785	COG0583	DNA-binding transcription factor activity
RC54_RS16800	COG1108	ABC-type Mn2 Zn2 transport systems permease components
RC54_RS16815	COG1136	(ABC) transporter
RC54_RS16845	COG1473	amidohydrolase
RC54_RS16850	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RC54_RS16855	COG4608	Belongs to the ABC transporter superfamily
RC54_RS16860	COG0444	Belongs to the ABC transporter superfamily
RC54_RS16865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RC54_RS16875	COG0747	negative chemotaxis
RC54_RS16880	COG0583	DNA-binding transcription factor activity
RC54_RS16920	COG2515	1-aminocyclopropane-1-carboxylate deaminase
RC54_RS16925	COG3047	cAMP biosynthetic process
RC54_RS16935	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RC54_RS16970	COG3278	Belongs to the heme-copper respiratory oxidase family
RC54_RS16980	COG2217	Heavy metal translocating P-type atpase
RC54_RS16990	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RC54_RS17015	COG0697	spore germination
RC54_RS17020	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
RC54_RS17025	COG2814	Major facilitator Superfamily
RC54_RS17030	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RC54_RS17045	COG0784	Response regulator, receiver
RC54_RS17080	COG4251	negative regulation of phosphorylation
RC54_RS17080	COG3706	GGDEF domain
RC54_RS17080	COG2203	Gaf domain
RC54_RS17080	COG5001	Diguanylate cyclase
RC54_RS17140	COG1051	belongs to the nudix hydrolase family
RC54_RS17145	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
RC54_RS17150	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
RC54_RS17155	COG0167	dihydroorotate dehydrogenase activity
RC54_RS17180	COG1434	Gram-negative-bacterium-type cell wall biogenesis
RC54_RS17185	COG0840	transmembrane signaling receptor activity
RC54_RS17190	COG4944	Protein of unknown function (DUF1109)
RC54_RS17195	COG1595	DNA-templated transcription, initiation
RC54_RS17210	COG3220	belongs to the UPF0276 family
RC54_RS17225	COG2226	methyltransferase
RC54_RS17250	COG4774	siderophore transport
RC54_RS17255	COG4774	siderophore transport
RC54_RS17260	COG3128	pkhd-type hydroxylase
RC54_RS17295	COG2252	PERMEase
RC54_RS17305	COG1529	Aldehyde oxidase and xanthine dehydrogenase
RC54_RS17315	COG0402	S-adenosylhomocysteine deaminase activity
RC54_RS17330	COG1566	PFAM secretion protein HlyD family protein
RC54_RS17335	COG2814	Major facilitator Superfamily
RC54_RS17350	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
RC54_RS17360	COG1047	Peptidyl-prolyl cis-trans
RC54_RS17365	COG2850	peptidyl-arginine hydroxylation
RC54_RS17375	COG1234	tRNA 3'-trailer cleavage
RC54_RS17380	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
RC54_RS17385	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RC54_RS17390	COG0180	Tryptophanyl-tRNA synthetase
RC54_RS17395	COG1994	Peptidase M50
RC54_RS17400	COG0009	L-threonylcarbamoyladenylate synthase
RC54_RS17405	COG0501	Belongs to the peptidase M48B family
RC54_RS17410	COG0613	PHP domain protein
RC54_RS17415	COG0596	Alpha beta hydrolase
RC54_RS17430	COG0626	cystathionine gamma-synthase activity
RC54_RS17440	COG1286	toxin biosynthetic process
RC54_RS17450	COG0285	dihydrofolate synthase activity
RC54_RS17455	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
RC54_RS17460	COG0159	tryptophan synthase activity
RC54_RS17465	COG0133	tryptophan synthase activity
RC54_RS17470	COG0135	phosphoribosylanthranilate isomerase activity
RC54_RS17475	COG0101	tRNA pseudouridine synthase activity
RC54_RS17490	COG0473	3-isopropylmalate dehydrogenase activity
RC54_RS17495	COG0066	3-isopropylmalate dehydratase activity
RC54_RS17505	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
RC54_RS17515	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
RC54_RS17520	COG2814	Major facilitator Superfamily
RC54_RS17535	COG1295	ribonuclease BN
RC54_RS17550	COG0277	FAD linked oxidase domain protein
RC54_RS17570	COG1178	ABC-type Fe3 transport system permease component
RC54_RS17575	COG3842	ATPase activity
RC54_RS17630	COG2186	Transcriptional regulator
RC54_RS17640	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
RC54_RS17645	COG0583	DNA-binding transcription factor activity
RC54_RS17650	COG4336	lyase activity
RC54_RS17655	COG2814	Major facilitator Superfamily
RC54_RS17660	COG0025	NhaP-type Na H and K H
RC54_RS17720	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
RC54_RS17725	COG0791	NLP P60 protein
RC54_RS17730	COG2186	Transcriptional regulator
RC54_RS17735	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
RC54_RS17750	COG3842	ATPase activity
RC54_RS17765	COG3833	ABC-type maltose transport systems, permease component
RC54_RS17810	COG4269	membrane
RC54_RS17830	COG0789	Transcriptional regulator
RC54_RS17835	COG0667	Aldo Keto reductase
RC54_RS17860	COG2204	response regulator
RC54_RS17870	COG0477	Major facilitator Superfamily
RC54_RS17885	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
RC54_RS17890	COG1546	Belongs to the CinA family
RC54_RS17895	COG0284	orotidine-5'-phosphate decarboxylase activity
RC54_RS17900	COG1704	LemA family
RC54_RS17920	COG2027	D-alanyl-D-alanine carboxypeptidase
RC54_RS17925	COG3706	GGDEF domain
RC54_RS17935	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
RC54_RS17955	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
RC54_RS17975	COG0642	Histidine kinase
RC54_RS17985	COG4774	siderophore transport
RC54_RS17990	COG3128	pkhd-type hydroxylase
RC54_RS17995	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RC54_RS18005	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RC54_RS18010	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RC54_RS18035	COG3833	ABC-type maltose transport systems, permease component
RC54_RS18040	COG1063	alcohol dehydrogenase
RC54_RS18045	COG3842	ATPase activity
RC54_RS18050	COG1917	Cupin 2, conserved barrel domain protein
RC54_RS18050	COG4977	sequence-specific DNA binding
RC54_RS18055	COG1070	Carbohydrate kinase
RC54_RS18115	COG0328	RNA-DNA hybrid ribonuclease activity
RC54_RS18125	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RC54_RS18130	COG0741	lytic transglycosylase activity
RC54_RS18130	COG1388	LysM domain
RC54_RS18135	COG4172	Belongs to the ABC transporter superfamily
RC54_RS18140	COG4239	(ABC) transporter, permease
RC54_RS18145	COG4174	ABC transporter (Permease)
RC54_RS18150	COG4166	transmembrane transport
RC54_RS18160	COG0513	Belongs to the DEAD box helicase family
RC54_RS18190	COG3009	Protein conserved in bacteria
RC54_RS18195	COG3008	intermembrane lipid transfer
RC54_RS18195	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
RC54_RS18200	COG2995	paraquat-inducible protein a
RC54_RS18205	COG2995	paraquat-inducible protein a
RC54_RS18210	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RC54_RS18225	COG1262	PFAM Formylglycine-generating sulfatase enzyme
RC54_RS18230	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
RC54_RS18235	COG1132	(ABC) transporter
RC54_RS18240	COG1902	pentaerythritol trinitrate reductase activity
RC54_RS18245	COG0586	Pfam SNARE associated Golgi protein
RC54_RS18275	COG1028	Short-chain dehydrogenase reductase Sdr
RC54_RS18280	COG1250	3-hydroxyacyl-CoA dehydrogenase
RC54_RS18285	COG3246	L-lysine catabolic process to acetate
RC54_RS18310	COG3416	Protein conserved in bacteria
RC54_RS18310	COG2943	transferase activity, transferring hexosyl groups
RC54_RS18315	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
RC54_RS18340	COG0583	DNA-binding transcription factor activity
RC54_RS18345	COG0640	Transcriptional regulator
RC54_RS18360	COG0717	Belongs to the dCTP deaminase family
RC54_RS18395	COG1643	Atp-dependent helicase
RC54_RS18400	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
RC54_RS18400	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
RC54_RS18405	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
RC54_RS18410	COG0612	Peptidase, M16
RC54_RS18420	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
RC54_RS18425	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
RC54_RS18425	COG4651	solute:proton antiporter activity
RC54_RS18430	COG1522	sequence-specific DNA binding
RC54_RS18470	COG0582	viral genome integration into host DNA
RC54_RS18495	COG4128	Pfam Zonular occludens toxin
RC54_RS18610	COG2031	fatty acid transporter
RC54_RS18615	COG0840	transmembrane signaling receptor activity
RC54_RS18625	COG1280	lysine exporter protein (LysE YggA)
RC54_RS18645	COG0840	transmembrane signaling receptor activity
RC54_RS18665	COG3706	GGDEF domain
RC54_RS18665	COG5001	Diguanylate cyclase
RC54_RS18665	COG4251	negative regulation of phosphorylation
RC54_RS18665	COG2203	Gaf domain
RC54_RS18675	COG0308	aminopeptidase N
RC54_RS18700	COG0697	spore germination
RC54_RS18705	COG0433	COG0433 Predicted ATPase
RC54_RS18710	COG0217	transcriptional regulatory protein
RC54_RS18715	COG0151	Belongs to the GarS family
RC54_RS18720	COG0668	transmembrane transport
RC54_RS18725	COG0408	coproporphyrinogen oxidase activity
RC54_RS18730	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
RC54_RS18735	COG0799	negative regulation of ribosome biogenesis
RC54_RS18740	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
RC54_RS18745	COG0424	maF-like protein
RC54_RS18765	COG1132	(ABC) transporter
RC54_RS18775	COG1442	glycosyl transferase family 8
RC54_RS18795	COG1054	Belongs to the UPF0176 family
RC54_RS18805	COG1741	Belongs to the pirin family
RC54_RS18810	COG0583	DNA-binding transcription factor activity
RC54_RS18815	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
RC54_RS18820	COG0513	Belongs to the DEAD box helicase family
RC54_RS18835	COG1737	Transcriptional regulator
RC54_RS18835	COG0837	glucose binding
RC54_RS18845	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
RC54_RS18860	COG0436	Aminotransferase
RC54_RS18865	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RC54_RS18870	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
RC54_RS18935	COG3778	Protein conserved in bacteria
RC54_RS18940	COG3299	homolog of phage Mu protein gp47
RC54_RS18985	COG4386	tail sheath protein
RC54_RS19125	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
RC54_RS19130	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
RC54_RS19135	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
RC54_RS19145	COG0779	Required for maturation of 30S ribosomal subunits
RC54_RS19150	COG1187	pseudouridine synthase activity
RC54_RS19155	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
RC54_RS19165	COG0069	glutamate synthase activity
RC54_RS19170	COG0425	Belongs to the sulfur carrier protein TusA family
RC54_RS19175	COG0494	nUDIX hydrolase
RC54_RS19180	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
RC54_RS19190	COG0584	glycerophosphoryl diester phosphodiesterase
RC54_RS19205	COG3279	Response regulator of the LytR AlgR family
RC54_RS19210	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
RC54_RS19230	COG2233	PERMEase
RC54_RS19235	COG2329	Antibiotic biosynthesis monooxygenase
RC54_RS19250	COG2925	Exonuclease
RC54_RS19260	COG1695	Transcriptional regulator
RC54_RS19275	COG2321	neutral zinc metallopeptidase
RC54_RS19290	COG2223	nitrite transmembrane transporter activity
RC54_RS19295	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
RC54_RS19305	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
RC54_RS19310	COG2181	nitrate reductase activity
RC54_RS19315	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
RC54_RS19320	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
RC54_RS19325	COG3850	Histidine kinase
RC54_RS19330	COG2197	response regulator
RC54_RS19335	COG2501	S4 domain
RC54_RS19370	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RC54_RS19370	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RC54_RS19390	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RC54_RS19405	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
RC54_RS19430	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RC54_RS19440	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RC54_RS19445	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RC54_RS19450	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
RC54_RS19460	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
RC54_RS19465	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
RC54_RS19470	COG3706	GGDEF domain
RC54_RS19480	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
RC54_RS19490	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
RC54_RS19500	COG0776	regulation of translation
RC54_RS19510	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
RC54_RS19525	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
RC54_RS19540	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
RC54_RS19545	COG0546	phosphoglycolate phosphatase activity
RC54_RS19580	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RC54_RS19605	COG2986	histidine ammonia-lyase
RC54_RS19630	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
RC54_RS19640	COG1028	Short-chain dehydrogenase reductase Sdr
RC54_RS19645	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
RC54_RS19670	COG3485	protocatechuate 3,4-dioxygenase
RC54_RS19675	COG0583	DNA-binding transcription factor activity
RC54_RS19690	COG3046	protein related to deoxyribodipyrimidine photolyase
RC54_RS19695	COG2204	response regulator
RC54_RS19700	COG0784	Response regulator, receiver
RC54_RS19700	COG2205	protein histidine kinase activity
RC54_RS19710	COG3850	Histidine kinase
RC54_RS19710	COG4999	Histidine kinase
RC54_RS19710	COG2205	protein histidine kinase activity
RC54_RS19710	COG3437	response regulator, receiver
RC54_RS19720	COG0835	chemotaxis
RC54_RS19720	COG0784	Response regulator, receiver
RC54_RS19730	COG4943	cyclic-guanylate-specific phosphodiesterase activity
RC54_RS19735	COG0840	transmembrane signaling receptor activity
RC54_RS19750	COG4566	intracellular signal transduction
RC54_RS19775	COG1028	Short-chain dehydrogenase reductase Sdr
RC54_RS19795	COG0840	transmembrane signaling receptor activity
RC54_RS19805	COG0745	RESPONSE REGULATOR receiver
RC54_RS19820	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
RC54_RS19825	COG0477	Major facilitator Superfamily
RC54_RS19835	COG1082	Xylose isomerase domain protein TIM barrel
RC54_RS19835	COG3185	4-Hydroxyphenylpyruvate dioxygenase
RC54_RS19850	COG1414	Transcriptional regulator
RC54_RS19855	COG1414	Transcriptional regulator
RC54_RS19860	COG0778	Nitroreductase
RC54_RS19865	COG0583	DNA-binding transcription factor activity
RC54_RS19885	COG1116	anion transmembrane transporter activity
RC54_RS19900	COG2186	Transcriptional regulator
RC54_RS19905	COG1024	Enoyl-CoA hydratase
RC54_RS19950	COG0745	RESPONSE REGULATOR receiver
RC54_RS19955	COG2205	protein histidine kinase activity
RC54_RS19960	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
RC54_RS19965	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
RC54_RS19970	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
RC54_RS19990	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RC54_RS19995	COG2130	NADP-dependent
RC54_RS20000	COG1309	transcriptional regulator
RC54_RS20010	COG4977	sequence-specific DNA binding
RC54_RS20015	COG1408	metallophosphoesterase
RC54_RS20030	COG0583	DNA-binding transcription factor activity
RC54_RS20040	COG0395	ABC-type sugar transport system, permease component
RC54_RS20045	COG1175	transmembrane transport
RC54_RS20050	COG1653	transport
RC54_RS20055	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
RC54_RS20060	COG0500	methyltransferase
RC54_RS20080	COG4942	peptidase
RC54_RS20100	COG0386	Belongs to the glutathione peroxidase family
RC54_RS20105	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
RC54_RS20115	COG3284	Transcriptional regulator
RC54_RS20120	COG0583	DNA-binding transcription factor activity
RC54_RS20130	COG1028	Short-chain dehydrogenase reductase Sdr
RC54_RS20150	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
RC54_RS20160	COG1301	dicarboxylic acid transport
RC54_RS20170	COG0247	lactate metabolic process
RC54_RS20175	COG0277	FAD linked oxidase domain protein
RC54_RS20180	COG0277	FAD linked oxidase domain protein
RC54_RS20185	COG0583	DNA-binding transcription factor activity
RC54_RS20190	COG0277	FAD linked oxidase domain protein
RC54_RS20195	COG2096	Adenosyltransferase
RC54_RS20205	COG0142	geranyltranstransferase activity
RC54_RS20210	COG1722	exodeoxyribonuclease VII activity
RC54_RS20230	COG0643	Histidine kinase
RC54_RS20230	COG2198	Histidine kinase
RC54_RS20235	COG0840	transmembrane signaling receptor activity
RC54_RS20245	COG1773	rubredoxin
RC54_RS20255	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
RC54_RS20260	COG0316	Belongs to the HesB IscA family
RC54_RS20275	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
RC54_RS20280	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
RC54_RS20285	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
RC54_RS20300	COG0418	dihydroorotase activity
RC54_RS20305	COG1126	abc transporter atp-binding protein
RC54_RS20310	COG0765	amino acid transport
RC54_RS20315	COG0765	amino acid transport
RC54_RS20325	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
RC54_RS20335	COG5265	(ABC) transporter
RC54_RS20345	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
RC54_RS20370	COG0318	PFAM AMP-dependent synthetase and ligase
RC54_RS20375	COG0243	molybdopterin cofactor binding
RC54_RS20390	COG1473	amidohydrolase
RC54_RS20430	COG0765	amino acid transport
RC54_RS20445	COG2721	sulfolactate sulfo-lyase activity
RC54_RS20455	COG1028	Short-chain dehydrogenase reductase Sdr
RC54_RS20465	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
RC54_RS20500	COG1024	Enoyl-CoA hydratase
RC54_RS20510	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
RC54_RS20515	COG2967	ApaG domain
RC54_RS20520	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
RC54_RS20525	COG0546	phosphoglycolate phosphatase activity
RC54_RS20535	COG0512	Glutamine amidotransferase of anthranilate synthase
RC54_RS20540	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
RC54_RS20545	COG0134	indole-3-glycerol-phosphate synthase activity
RC54_RS20550	COG0477	Major facilitator Superfamily
RC54_RS20555	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
RC54_RS20570	COG2226	methyltransferase
RC54_RS20590	COG1238	metal cluster binding
RC54_RS20595	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
RC54_RS20600	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
RC54_RS20600	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
RC54_RS20615	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
RC54_RS20620	COG1660	Displays ATPase and GTPase activities
RC54_RS20625	COG1194	a g-specific adenine glycosylase
RC54_RS20630	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
RC54_RS20640	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
RC54_RS20645	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
RC54_RS20655	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
RC54_RS20660	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
RC54_RS20675	COG0067	glutamate synthase
RC54_RS20675	COG0069	glutamate synthase activity
RC54_RS20675	COG0070	glutamate synthase
RC54_RS20685	COG0861	Integral membrane protein TerC family
RC54_RS20695	COG0583	DNA-binding transcription factor activity
RC54_RS20705	COG0477	Major facilitator Superfamily
RC54_RS20710	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
RC54_RS20720	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
RC54_RS20735	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RC54_RS20770	COG0629	single-stranded DNA binding
RC54_RS20775	COG2814	Major facilitator Superfamily
RC54_RS20780	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
RC54_RS20790	COG5285	phytanoyl-CoA dioxygenase
RC54_RS20795	COG0840	transmembrane signaling receptor activity
RC54_RS20800	COG0840	transmembrane signaling receptor activity
RC54_RS20815	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
RC54_RS20825	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
RC54_RS20830	COG1137	ATPase activity
RC54_RS20835	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
RC54_RS20840	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
RC54_RS20845	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
RC54_RS20855	COG1028	Short-chain dehydrogenase reductase Sdr
RC54_RS20865	COG1522	sequence-specific DNA binding
RC54_RS20875	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
RC54_RS20895	COG1414	Transcriptional regulator
RC54_RS20900	COG3485	protocatechuate 3,4-dioxygenase
RC54_RS20905	COG3485	protocatechuate 3,4-dioxygenase
RC54_RS20910	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
RC54_RS20915	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RC54_RS20920	COG3041	Addiction module toxin RelE StbE family
RC54_RS20925	COG3077	Addiction module antitoxin, RelB DinJ family
RC54_RS20935	COG2249	NAD(P)H dehydrogenase (quinone) activity
RC54_RS20970	COG0683	leucine binding
RC54_RS20980	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RC54_RS21005	COG0183	Belongs to the thiolase family
RC54_RS21010	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
RC54_RS21020	COG1414	Transcriptional regulator
RC54_RS21030	COG0683	leucine binding
RC54_RS21035	COG1024	Enoyl-CoA hydratase
RC54_RS21040	COG1022	Amp-dependent synthetase and ligase
RC54_RS21045	COG0183	Belongs to the thiolase family
RC54_RS21080	COG1960	acyl-CoA dehydrogenase activity
RC54_RS21095	COG0840	transmembrane signaling receptor activity
RC54_RS21220	COG3179	chitinase
RC54_RS21235	COG1944	ATP diphosphatase activity
RC54_RS21240	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
RC54_RS21250	COG0747	negative chemotaxis
RC54_RS21260	COG2969	positive regulation of protein catabolic process
RC54_RS21265	COG0625	glutathione transferase activity
RC54_RS21270	COG2857	Cytochrome c1
RC54_RS21275	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
RC54_RS21280	COG0723	plastoquinol--plastocyanin reductase activity
RC54_RS21285	COG1970	mechanosensitive ion channel activity
RC54_RS21290	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
RC54_RS21305	COG0805	protein transport
RC54_RS21310	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
RC54_RS21315	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
RC54_RS21325	COG0140	phosphoribosyl-ATP diphosphatase activity
RC54_RS21330	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
RC54_RS21335	COG0107	imidazoleglycerol-phosphate synthase activity
RC54_RS21340	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
RC54_RS21350	COG0131	Imidazoleglycerol-phosphate dehydratase
RC54_RS21355	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
RC54_RS21365	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
RC54_RS21370	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
RC54_RS21375	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
RC54_RS21380	COG0271	Belongs to the BolA IbaG family
RC54_RS21385	COG0842	Transport permease protein
RC54_RS21390	COG1131	(ABC) transporter
RC54_RS21405	COG2853	Lipoprotein
RC54_RS21410	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
RC54_RS21415	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
RC54_RS21420	COG1127	ABC transporter
RC54_RS21425	COG0012	GTP binding
RC54_RS21430	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
RC54_RS21450	COG0511	ligase activity, forming carbon-carbon bonds
RC54_RS21455	COG0439	Biotin carboxylase
RC54_RS21465	COG1984	allophanate hydrolase subunit 2
RC54_RS21505	COG1012	belongs to the aldehyde dehydrogenase family
RC54_RS21505	COG2030	dehydratase
RC54_RS21510	COG0683	leucine binding
RC54_RS21525	COG3396	Phenylacetate-CoA oxygenase
RC54_RS21530	COG3460	Phenylacetate-CoA oxygenase
RC54_RS21535	COG3396	Phenylacetate-CoA oxygenase
RC54_RS21540	COG2151	metal-sulfur cluster biosynthetic enzyme
RC54_RS21545	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RC54_RS21550	COG1024	Enoyl-CoA hydratase
RC54_RS21555	COG1250	3-hydroxyacyl-CoA dehydrogenase
RC54_RS21560	COG2050	protein possibly involved in aromatic compounds catabolism
RC54_RS21570	COG0183	Belongs to the thiolase family
RC54_RS21575	COG1024	Enoyl-CoA hydratase
RC54_RS21595	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
RC54_RS21600	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
RC54_RS21605	COG0742	ribosomal rna small subunit methyltransferase
RC54_RS21610	COG0612	Peptidase, M16
RC54_RS21620	COG0612	Peptidase, M16
RC54_RS21630	COG2884	Cell division ATP-binding protein ftsE
RC54_RS21645	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
RC54_RS21650	COG1999	signal sequence binding
RC54_RS21655	COG0109	protoheme IX farnesyltransferase activity
RC54_RS21660	COG1612	heme a metabolic process
RC54_RS21690	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
RC54_RS21710	COG2226	methyltransferase
RC54_RS21715	COG1040	competence protein
RC54_RS21725	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
RC54_RS21735	COG2984	ABC transporter substrate binding protein
RC54_RS21750	COG2847	Copper chaperone PCu(A)C
RC54_RS21755	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
RC54_RS21770	COG0683	leucine binding
RC54_RS21785	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
RC54_RS21835	COG0232	Belongs to the dGTPase family. Type 2 subfamily
RC54_RS21845	COG2183	response to ionizing radiation
RC54_RS21850	COG0193	aminoacyl-tRNA hydrolase activity
RC54_RS21860	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RC54_RS21880	COG4128	Pfam Zonular occludens toxin
RC54_RS21900	COG0582	viral genome integration into host DNA
RC54_RS21980	COG1216	Glycosyl transferase, family 2
RC54_RS21990	COG0562	UDP-galactopyranose mutase
RC54_RS21995	COG1210	Utp--glucose-1-phosphate uridylyltransferase
RC54_RS22015	COG1028	Short-chain dehydrogenase reductase Sdr
RC54_RS22050	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
RC54_RS22055	COG3622	Belongs to the hyi family
RC54_RS22060	COG2271	Major facilitator Superfamily
RC54_RS22065	COG0235	Class ii aldolase
RC54_RS22070	COG3395	kinase activity
RC54_RS22075	COG2084	Dehydrogenase
RC54_RS22080	COG2186	Transcriptional regulator
RC54_RS22100	COG2807	transmembrane transport
RC54_RS22105	COG2207	Transcriptional regulator
RC54_RS22110	COG3025	triphosphatase activity
RC54_RS22120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RC54_RS22130	COG0765	amino acid transport
RC54_RS22135	COG1126	abc transporter atp-binding protein
RC54_RS22140	COG1073	alpha beta
RC54_RS22145	COG1280	lysine exporter protein (LysE YggA)
RC54_RS22160	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
RC54_RS22165	COG1609	Transcriptional regulator
RC54_RS22170	COG1953	Uracil, thiamine, allantoin
RC54_RS22205	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RC54_RS22210	COG3845	ABC transporter
RC54_RS22215	COG4603	Belongs to the binding-protein-dependent transport system permease family
RC54_RS22220	COG1079	Belongs to the binding-protein-dependent transport system permease family
RC54_RS22235	COG1196	nuclear chromosome segregation
RC54_RS22245	COG3093	addiction module antidote protein HigA
RC54_RS22250	COG0850	regulation of cytokinetic process
RC54_RS22260	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
RC54_RS22270	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
RC54_RS22275	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
RC54_RS22280	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
RC54_RS22285	COG2890	protein-(glutamine-N5) methyltransferase activity
RC54_RS22295	COG3186	Phenylalanine-4-hydroxylase
RC54_RS22305	COG0617	tRNA 3'-terminal CCA addition
RC54_RS22325	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
RC54_RS22335	COG1950	PFAM Membrane protein of
RC54_RS22340	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
RC54_RS22345	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
RC54_RS22355	COG1560	Kdo2-lipid A biosynthetic process
RC54_RS22360	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
RC54_RS22370	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
RC54_RS22380	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
RC54_RS22400	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
RC54_RS22410	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
RC54_RS22430	COG2945	thiolester hydrolase activity
RC54_RS22435	COG1686	Belongs to the peptidase S11 family
RC54_RS22440	COG3634	alkyl hydroperoxide reductase activity
RC54_RS22445	COG0450	alkyl hydroperoxide reductase
RC54_RS22450	COG0824	Thioesterase
RC54_RS22455	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
RC54_RS22460	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RC54_RS22470	COG0252	asparaginase activity
RC54_RS22475	COG0583	DNA-binding transcription factor activity
RC54_RS22490	COG0210	DNA helicase
RC54_RS22535	COG0765	amino acid transport
RC54_RS22540	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
RC54_RS22540	COG0493	'glutamate synthase
RC54_RS22550	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
RC54_RS22555	COG0587	DNA-directed DNA polymerase activity
RC54_RS22580	COG2974	May be involved in recombination
RC54_RS22585	COG0579	oxidoreductase
RC54_RS22590	COG1309	transcriptional regulator
RC54_RS22595	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
RC54_RS22610	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
RC54_RS22615	COG0706	membrane insertase activity
RC54_RS22620	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
RC54_RS22625	COG0594	ribonuclease P activity
RC54_RS22630	COG0230	Belongs to the bacterial ribosomal protein bL34 family
RC54_RS22635	COG2766	serine protein kinase
RC54_RS22640	COG2718	Belongs to the UPF0229 family
RC54_RS22645	COG2719	SpoVR family
RC54_RS22670	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
RC54_RS22675	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
RC54_RS22680	COG0300	oxidoreductase activity
RC54_RS22685	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
RC54_RS22695	COG0018	arginyl-trna synthetase
RC54_RS22700	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
RC54_RS22705	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
RC54_RS22715	COG2326	polyphosphate kinase activity
RC54_RS22720	COG1832	CoA-binding protein
RC54_RS22725	COG0355	proton-transporting ATP synthase activity, rotational mechanism
RC54_RS22730	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
RC54_RS22735	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
RC54_RS22740	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
RC54_RS22745	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
RC54_RS22750	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
RC54_RS22760	COG0356	it plays a direct role in the translocation of protons across the membrane
RC54_RS22775	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
RC54_RS22780	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
RC54_RS22810	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
RC54_RS22825	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RC54_RS22830	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
RC54_RS22835	COG1088	dTDP-glucose 4,6-dehydratase activity
RC54_RS22840	COG3959	Transketolase, thiamine diphosphate binding domain
RC54_RS22845	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
RC54_RS22885	COG1028	Short-chain dehydrogenase reductase Sdr
RC54_RS22890	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
RC54_RS22890	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
RC54_RS22925	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
RC54_RS22940	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RC54_RS22945	COG0642	Histidine kinase
RC54_RS22975	COG4680	protein conserved in bacteria
RC54_RS22990	COG1448	Aminotransferase
RC54_RS22995	COG0037	tRNA processing
RC54_RS23010	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
RC54_RS23020	COG1522	sequence-specific DNA binding
RC54_RS23040	COG1012	belongs to the aldehyde dehydrogenase family
RC54_RS23050	COG2207	Transcriptional regulator
RC54_RS23060	COG1538	Outer membrane efflux protein
RC54_RS23065	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RC54_RS23070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RC54_RS23075	COG4773	Receptor
RC54_RS23115	COG3707	response regulator
RC54_RS23130	COG4770	biotin carboxylase activity
RC54_RS23145	COG3842	ATPase activity
RC54_RS23185	COG0179	Fumarylacetoacetate (FAA) hydrolase
RC54_RS23215	COG2207	Transcriptional regulator
RC54_RS23220	COG1233	COG1233 Phytoene dehydrogenase and related
RC54_RS23225	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
RC54_RS23230	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RC54_RS23250	COG0840	transmembrane signaling receptor activity
RC54_RS23260	COG1064	alcohol dehydrogenase
RC54_RS23285	COG1609	Transcriptional regulator
RC54_RS23285	COG2207	Transcriptional regulator
RC54_RS23290	COG4213	ABC transporter substrate-binding protein
RC54_RS23295	COG1129	ABC transporter
RC54_RS23300	COG4214	carbohydrate transport
RC54_RS23310	COG0129	dihydroxy-acid dehydratase activity
RC54_RS23320	COG2203	Gaf domain
RC54_RS23320	COG3706	GGDEF domain
RC54_RS23320	COG4251	negative regulation of phosphorylation
RC54_RS23320	COG5001	Diguanylate cyclase
RC54_RS23325	COG1686	Belongs to the peptidase S11 family
RC54_RS23355	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
RC54_RS23360	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
RC54_RS23380	COG0583	DNA-binding transcription factor activity
RC54_RS23405	COG4566	intracellular signal transduction
RC54_RS23425	COG0783	Belongs to the Dps family
RC54_RS23445	COG1335	isochorismatase
RC54_RS23465	COG4191	Histidine kinase
RC54_RS23470	COG2207	Transcriptional regulator
RC54_RS23485	COG0583	DNA-binding transcription factor activity
RC54_RS23490	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
RC54_RS23495	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
RC54_RS23500	COG3842	ATPase activity
RC54_RS23510	COG1840	ABC-type Fe3 transport system, periplasmic component
RC54_RS23535	COG0840	transmembrane signaling receptor activity
RC54_RS23540	COG2986	histidine ammonia-lyase
RC54_RS23550	COG1301	dicarboxylic acid transport
RC54_RS23560	COG0840	transmembrane signaling receptor activity
RC54_RS23575	COG0667	Aldo Keto reductase
RC54_RS23590	COG1653	transport
RC54_RS23595	COG0583	DNA-binding transcription factor activity
RC54_RS23600	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
RC54_RS23605	COG3064	Membrane
RC54_RS23610	COG1247	-acetyltransferase
RC54_RS23625	COG2010	Cytochrome c
RC54_RS23635	COG0640	Transcriptional regulator
RC54_RS23655	COG0583	DNA-binding transcription factor activity
RC54_RS23660	COG1051	belongs to the nudix hydrolase family
RC54_RS23660	COG1056	cytidyltransferase-related domain
RC54_RS23665	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
RC54_RS23665	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RC54_RS23670	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
RC54_RS23715	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
RC54_RS23725	COG2271	Major facilitator Superfamily
RC54_RS23745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RC54_RS23750	COG2194	sulfuric ester hydrolase activity
RC54_RS23760	COG0840	transmembrane signaling receptor activity
RC54_RS23770	COG2814	Major facilitator Superfamily
RC54_RS23790	COG0625	glutathione transferase activity
RC54_RS23795	COG2271	Major facilitator Superfamily
RC54_RS23800	COG2186	Transcriptional regulator
RC54_RS23805	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RC54_RS23815	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RC54_RS23825	COG2205	protein histidine kinase activity
RC54_RS23830	COG0745	RESPONSE REGULATOR receiver
RC54_RS23910	COG4221	oxidoreductase activity
RC54_RS23915	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
RC54_RS23920	COG2814	Major facilitator Superfamily
RC54_RS23930	COG4191	Histidine kinase
RC54_RS23935	COG4251	negative regulation of phosphorylation
RC54_RS23935	COG3706	GGDEF domain
RC54_RS23935	COG2203	Gaf domain
RC54_RS23935	COG5001	Diguanylate cyclase
RC54_RS23950	COG4566	intracellular signal transduction
RC54_RS23955	COG0583	DNA-binding transcription factor activity
RC54_RS23960	COG2910	NAD(P)H-binding
RC54_RS24005	COG0252	asparaginase activity
RC54_RS24030	COG0702	epimerase
RC54_RS24045	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
RC54_RS24070	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RC54_RS24090	COG0559	Belongs to the binding-protein-dependent transport system permease family
RC54_RS24095	COG4177	L-phenylalanine transmembrane transporter activity
RC54_RS24120	COG0840	transmembrane signaling receptor activity
RC54_RS24125	COG2175	clavaminate synthase activity
RC54_RS24155	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
RC54_RS24160	COG0154	amidase activity
RC54_RS24165	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
RC54_RS24170	COG1077	Cell shape determining protein MreB Mrl
RC54_RS24175	COG1792	Involved in formation and maintenance of cell shape
RC54_RS24185	COG0768	penicillin binding
RC54_RS24190	COG0772	Belongs to the SEDS family
RC54_RS24205	COG3107	peptidoglycan biosynthetic process
RC54_RS24210	COG0792	nuclease activity
RC54_RS24215	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
RC54_RS24220	COG2823	Periplasmic or secreted lipoprotein
RC54_RS24235	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
RC54_RS24240	COG0708	Exodeoxyribonuclease III
RC54_RS24250	COG2922	Belongs to the Smg family
RC54_RS24255	COG0758	DNA mediated transformation
RC54_RS24260	COG0242	peptide deformylase activity
RC54_RS24275	COG1960	acyl-CoA dehydrogenase activity
RC54_RS24285	COG3012	SEC-C Motif Domain Protein
RC54_RS24290	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
RC54_RS24345	COG3210	domain, Protein
RC54_RS24345	COG3210	domain, Protein
RC54_RS24350	COG2831	hemolysin activation secretion protein
RC54_RS24355	COG2070	2-Nitropropane dioxygenase
RC54_RS24370	COG2223	nitrite transmembrane transporter activity
RC54_RS24385	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
RC54_RS24400	COG0318	PFAM AMP-dependent synthetase and ligase
RC54_RS24420	COG0488	(ABC) transporter
RC54_RS24430	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
RC54_RS24435	COG0154	amidase activity
RC54_RS24440	COG0444	Belongs to the ABC transporter superfamily
RC54_RS24445	COG4608	Belongs to the ABC transporter superfamily
RC54_RS24450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RC54_RS24460	COG0747	negative chemotaxis
RC54_RS24470	COG2814	Major facilitator Superfamily
RC54_RS24485	COG2203	Gaf domain
RC54_RS24485	COG3706	GGDEF domain
RC54_RS24485	COG4251	negative regulation of phosphorylation
RC54_RS24485	COG5001	Diguanylate cyclase
RC54_RS24510	COG0411	ABC transporter
RC54_RS24520	COG0829	nickel cation binding
RC54_RS24525	COG0831	urea catabolic process
RC54_RS24530	COG0832	Belongs to the urease beta subunit family
RC54_RS24535	COG0804	urea catabolic process
RC54_RS24540	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
RC54_RS24545	COG0830	nickel cation binding
RC54_RS24550	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
RC54_RS24585	COG2823	Periplasmic or secreted lipoprotein
RC54_RS24590	COG2204	response regulator
RC54_RS24600	COG2205	protein histidine kinase activity
RC54_RS24605	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RC54_RS24610	COG2814	Major facilitator Superfamily
RC54_RS24625	COG0302	gtp cyclohydrolase
RC54_RS24650	COG0765	amino acid transport
RC54_RS24655	COG1126	abc transporter atp-binding protein
RC54_RS24695	COG0697	spore germination
RC54_RS24730	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
RC54_RS24745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RC54_RS24745	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
RC54_RS24755	COG0523	cobalamin synthesis protein
RC54_RS24760	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RC54_RS24780	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
RC54_RS24785	COG0321	lipoyl(octanoyl) transferase activity
RC54_RS24795	COG0583	DNA-binding transcription factor activity
RC54_RS24800	COG2921	Belongs to the UPF0250 family
RC54_RS24820	COG4178	(ABC) transporter
RC54_RS24825	COG0840	transmembrane signaling receptor activity
RC54_RS24830	COG1132	(ABC) transporter
RC54_RS24840	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
RC54_RS24850	COG1192	Involved in chromosome partitioning
RC54_RS24860	COG3040	lipid binding
RC54_RS24865	COG0357	Ribosomal RNA small subunit methyltransferase G
RC54_RS24870	COG0445	tRNA wobble uridine modification
RC54_RS24880	COG4214	carbohydrate transport
RC54_RS24900	COG0411	ABC transporter
RC54_RS24925	COG2982	Protein involved in outer membrane biogenesis
RC54_RS24945	COG0121	glutamine amidotransferase